Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AACS "ACSF1, FLJ12389, SUR-5" ENSG00000081760 "Acetoacetyl-CoA synthetase" Q86V21 12 125065434-125143333 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 67.1;Excitatory neurons: 59.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058815 Approved Approved Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA058815: AB_2683826" "unprognostic (1.28e-1)" "unprognostic (9.78e-2)" "unprognostic (1.86e-1)" "unprognostic (1.06e-1)" "unprognostic (1.98e-3)" "unprognostic (9.46e-3)" "unprognostic (6.60e-6)" "unprognostic (3.03e-2)" "unprognostic (3.32e-2)" "unprognostic (2.45e-2)" "unprognostic (2.38e-2)" "unprognostic (3.04e-1)" "unprognostic (2.69e-2)" "unprognostic (1.69e-1)" "unprognostic (3.73e-2)" "unprognostic (7.71e-2)" "unprognostic (6.80e-2)" 31.7 7.8 6.4 5.6 8.2 3.7 43.4 2.8 11.0 14.6 3.2 12.7 17.9 6.3 8.7 30.9 8.5 7.6 7.4 9.1 3.7 10.3 3.9 6.2 5.8 6.1 3.1 6.0 12.8 9.6 8.5 6.1 6.0 8.6 11.3 6.2 48.2 7.5 5.5 40.4 10.4 5.8 2.4 5.2 16.9 13.5 5.0 10.4 10.0 7.6 10.2 6.1 14.3 6.5 26.8 26.2 11.2 15.3 40.3 26.1 18.7 21.2 20.1 24.6 21.8 34.0 17.4 16.5 21.3 25.7 10.6 28.4 21.0 22.8 13.2 17.8 19.2 13.1 16.9 26.2 33.5 9.4 12.8 29.1 18.2 21.0 21.0 30.8 18.1 9.5 9.4 9.9 15.9 49.1 10.8 12.7 14.2 28.0 30.4 2.1 28.2 23.0 25.0 40.2 29.7 8.6 22.4 35.0 16.6 10.8 26.2 20.7 17.4 11.8 18.7 13.4 16.4 22.0 13.6 18.0 14.8 15.4 13.2 7.7 2.1 5.9 3.3 0.6 4.4 2.4 3.1 2.5 2.4 1.2 4.4 3.0 0.3 5.4 0.7 9.9 2.1 3.4 6.4 8.2 2.8 11.0 9.1 3.7 6.1 3.1 6.0 2.4 5.0 6.5 4.2 6.4 17.3 16.3 4.5 16.6 5.6 14.1 9.1 20.9 23.6 16.9 9.4 17.2 12.0 5.5 27.1 2.1 6.5 14.0 7.9 11.0 67.1 6.3 15.3 6.5 25.2 0.8 59.4 10.7 8.7 11.8 13.3 12.3 2.5 13.1 2.2 4.2 4.8 6.7 28.6 22.0 16.2 4.1 9.0 22.5 9.3 3.9 5.4 5.6 5.4 5.6 5.2 12.1 12.5 9.9 7.4 5.3 12.1 8.2 10.7 6.5 5.7 21.8 0.0 8.6 7.7 22.0 5.3 25.3 28.1 2.5 8.1 20.8 15.8 5.6 AADAT "KAT2, KATII, KYAT2" ENSG00000109576 "Aminoadipate aminotransferase" Q8N5Z0 4 170060222-170091699 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 67.1" "Cell type enhanced" "Detected in many" "Astrocytes: 22.2;Extravillous trophoblasts: 71.3;Hepatocytes: 29.3;Spermatogonia: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA037502 Enhanced Approved "Vesicles,Plasma membrane" NA NA "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" Vesicles "HPA037502: AB_10671759" "unprognostic (1.90e-1)" "unprognostic (1.82e-2)" "prognostic favorable (5.59e-4)" "unprognostic (4.21e-2)" "unprognostic (1.30e-1)" "unprognostic (1.06e-1)" "unprognostic (7.41e-2)" "unprognostic (1.03e-2)" "unprognostic (2.97e-2)" "unprognostic (3.38e-2)" "unprognostic (1.23e-2)" "unprognostic (3.55e-1)" "unprognostic (1.35e-1)" "unprognostic (1.23e-2)" "unprognostic (1.39e-1)" "unprognostic (7.28e-3)" "unprognostic (1.17e-2)" 3.3 2.8 6.2 1.9 6.8 0.3 4.7 3.8 9.8 9.8 11.3 6.2 1.6 10.5 5.9 2.6 6.3 3.9 2.7 6.5 6.7 6.8 67.1 4.9 0.7 5.8 5.6 4.7 5.6 6.0 6.1 1.9 6.5 14.4 5.0 11.8 1.7 5.3 4.0 1.4 2.3 7.3 4.8 1.7 3.6 8.2 6.1 1.5 7.5 2.4 0.8 6.4 5.7 8.7 3.5 8.5 25.0 0.0 4.9 18.9 9.0 8.7 4.2 4.9 5.0 8.4 1.0 0.1 1.4 9.8 6.5 2.9 11.3 4.1 3.4 0.0 9.7 0.0 10.0 14.0 3.9 0.1 3.8 7.7 2.5 4.0 5.1 13.5 4.7 11.4 1.5 0.1 19.0 8.9 4.3 0.1 19.0 9.6 7.6 0.0 7.8 0.0 4.4 15.3 20.1 23.5 7.0 1.7 8.5 8.0 0.1 1.7 3.2 12.5 13.4 14.3 13.9 0.1 0.0 0.1 12.5 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 6.8 3.8 9.8 6.5 6.7 5.8 5.6 6.5 4.8 6.1 8.7 0.9 0.0 5.9 22.2 0.3 0.9 2.8 0.9 6.2 6.0 3.9 1.0 1.2 1.5 2.1 0.0 2.1 2.8 0.0 0.7 0.0 1.6 0.5 3.7 7.4 0.7 6.7 0.0 15.4 2.2 71.3 3.2 3.1 6.0 0.0 6.2 0.7 29.3 1.6 0.0 13.6 2.8 0.0 0.3 0.9 1.4 1.2 0.4 1.8 5.6 0.0 2.7 0.0 17.6 14.0 1.1 1.6 2.2 0.0 4.0 0.2 8.4 8.5 9.1 6.6 3.9 4.2 14.5 27.1 3.0 0.4 5.6 0.3 3.3 3.1 1.8 AAK1 "DKFZp686K16132, KIAA1048" ENSG00000115977 "AP2 associated kinase 1" Q2M2I8 2 69457997-69674349 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 89.7" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 777.7;Rod photoreceptor cells: 640.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 6 "cerebral cortex: 31.0" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017931, HPA020289" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA No "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "Vesicles, Plasma membrane" Cytosol "HPA017931: AB_1844406, HPA020289: AB_1844407" "unprognostic (2.11e-3)" "unprognostic (3.18e-2)" "unprognostic (3.67e-1)" "unprognostic (1.01e-3)" "unprognostic (5.06e-2)" "unprognostic (4.04e-2)" "unprognostic (4.23e-2)" "unprognostic (1.14e-1)" "unprognostic (3.52e-1)" "prognostic unfavorable (3.19e-4)" "unprognostic (1.24e-1)" "unprognostic (7.65e-2)" "unprognostic (4.18e-2)" "unprognostic (1.30e-1)" "unprognostic (5.40e-2)" "unprognostic (6.76e-3)" "unprognostic (1.18e-1)" 9.1 12.6 0.3 8.1 0.6 12.0 8.1 0.9 31.0 7.1 0.0 7.0 4.6 9.9 9.9 7.4 7.5 5.4 20.4 2.9 0.0 10.5 5.1 10.3 9.0 4.7 2.9 5.5 13.1 89.7 13.7 9.9 3.5 8.6 6.3 28.2 6.7 8.2 13.0 6.3 8.5 7.6 0.0 8.6 12.6 6.7 4.8 13.2 23.4 6.7 7.7 7.8 7.1 4.8 25.1 15.3 14.6 12.3 13.7 14.3 41.0 19.4 16.8 12.0 11.3 15.6 10.0 0.9 4.6 27.6 16.5 11.4 11.7 11.4 27.1 20.6 4.4 13.3 9.0 10.0 11.7 9.5 31.3 12.9 9.6 23.7 30.9 10.2 27.4 12.3 3.2 14.1 22.5 3.7 8.8 5.6 6.4 4.9 8.3 5.8 13.8 2.2 10.0 51.0 4.2 6.6 12.0 8.8 10.2 9.9 5.3 12.9 25.6 26.4 17.5 19.7 19.4 12.9 3.9 1.5 23.0 16.0 19.1 1.4 0.5 0.2 1.4 0.2 1.4 0.1 1.3 1.0 0.3 0.3 1.7 1.5 1.5 1.1 2.2 0.2 1.0 0.5 0.3 0.6 0.9 31.0 2.9 0.0 4.7 2.9 3.5 0.0 4.8 4.8 54.6 35.3 34.2 77.7 13.4 15.9 20.8 15.9 32.5 254.4 42.2 40.9 86.7 102.9 19.3 143.5 777.7 81.6 149.1 130.6 43.0 46.0 23.9 36.6 67.4 56.0 72.1 35.3 265.8 67.4 56.3 29.5 44.9 65.7 21.0 24.4 118.2 38.2 62.4 306.2 327.7 31.6 12.2 128.8 23.5 32.7 38.2 67.1 10.6 156.4 72.7 53.2 252.4 147.8 113.9 55.9 76.3 46.6 57.4 42.1 56.0 90.0 10.7 640.8 19.7 26.7 45.5 46.9 59.3 23.3 9.9 213.3 158.1 33.6 21.7 49.0 AASS "LKRSDH, LORSDH" ENSG00000008311 "Aminoadipate-semialdehyde synthase" Q9UDR5 7 122064583-122144308 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 44.3" "Cell type enhanced" "Detected in many" "Astrocytes: 145.9;Hepatocytes: 113.9;Oligodendrocyte precursor cells: 106.1;Oligodendrocytes: 132.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 41.5;NTERA-2: 55.3;SuSa: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020637, HPA020728, HPA020734" Enhanced Approved Nucleoplasm,Vesicles,Mitochondria Yes No 19000 "Cluster 15: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "Nucleoplasm, Vesicles" "HPA020637: AB_1844415, HPA020728: AB_1844416, HPA020734: AB_1844417" "unprognostic (4.84e-2)" "unprognostic (2.29e-1)" "unprognostic (7.91e-4)" "unprognostic (6.08e-2)" "unprognostic (1.49e-2)" "unprognostic (8.00e-2)" "prognostic favorable (9.81e-4)" "unprognostic (4.48e-3)" "unprognostic (2.38e-1)" "unprognostic (1.47e-1)" "unprognostic (1.98e-1)" "unprognostic (1.99e-1)" "unprognostic (7.76e-3)" "unprognostic (8.56e-3)" "unprognostic (1.55e-1)" "unprognostic (6.50e-2)" "unprognostic (2.67e-1)" 9.7 5.9 10.0 1.8 12.2 0.2 8.4 10.3 14.4 8.2 15.5 5.2 0.9 9.5 7.5 3.2 11.7 2.1 9.2 9.4 10.6 13.9 44.3 6.3 1.4 11.6 11.0 25.2 4.8 7.1 3.5 3.2 11.4 5.4 1.4 3.7 3.5 4.8 8.6 2.8 3.6 4.4 10.1 2.9 5.5 2.2 11.0 1.5 4.7 6.2 1.4 6.9 6.2 11.8 0.1 0.0 21.9 41.5 27.3 13.5 9.4 5.4 8.0 7.3 9.1 12.6 0.1 0.0 0.2 6.6 8.3 4.1 33.5 16.8 9.6 0.0 12.2 9.4 4.3 12.5 22.0 0.0 2.9 12.2 0.5 9.2 7.1 18.9 19.8 12.1 2.7 15.5 5.1 0.1 0.9 0.0 55.3 0.1 1.7 11.8 16.3 0.3 5.3 2.4 2.7 0.7 1.5 0.0 5.3 37.8 0.5 0.0 8.1 13.6 3.4 7.0 8.3 3.5 3.0 0.0 4.9 0.8 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.0 12.2 10.3 14.4 9.4 10.6 11.6 11.0 11.4 10.1 11.0 11.8 16.0 9.6 37.8 145.9 2.1 6.2 9.0 2.8 14.8 7.0 8.7 6.3 9.7 14.3 5.6 14.7 16.7 11.6 1.5 0.6 0.0 2.7 12.2 4.1 24.0 11.7 3.0 5.2 5.0 1.8 3.3 14.4 5.6 7.7 3.8 18.1 24.7 113.9 1.5 11.8 4.4 2.6 2.0 2.2 2.5 7.4 19.0 1.4 12.4 35.6 0.0 8.9 0.0 106.1 132.5 2.3 2.5 24.5 1.6 4.7 5.4 8.6 0.9 3.3 19.7 38.9 15.8 12.4 2.4 7.8 4.7 5.1 2.1 8.0 1.9 4.8 ABCA1 "ABC1, HDLDT1, TGD" ENSG00000165029 "ATP binding cassette subfamily A member 1" O95477 9 104781006-104928155 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transport" Translocase "Atherosclerosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 105.8;Hepatocytes: 175.5;Kupffer cells: 169.1;Langerhans cells: 109.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 13.1;neutrophil: 10.6" "Lineage enriched" "Detected in many" 8 "granulocytes: 13.1" "Cell line enhanced" "Detected in many" "HSkMC: 34.1;U-87 MG: 79.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057283, CAB069889" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Vesicles" "CAB069889: AB_10002789, HPA057283: AB_2683396" "unprognostic (1.58e-2)" "unprognostic (2.54e-1)" "unprognostic (1.46e-1)" "unprognostic (2.80e-1)" "unprognostic (7.47e-3)" "unprognostic (1.85e-1)" "unprognostic (9.22e-2)" "unprognostic (9.80e-2)" "unprognostic (2.04e-1)" "unprognostic (7.28e-3)" "unprognostic (2.14e-1)" "unprognostic (4.78e-2)" "unprognostic (1.04e-2)" "unprognostic (2.00e-3)" "unprognostic (2.51e-2)" "unprognostic (6.71e-2)" "unprognostic (2.57e-1)" 24.7 36.5 12.0 11.0 29.1 20.7 13.3 14.4 12.5 7.4 4.1 16.3 4.5 5.6 8.2 4.9 8.0 15.0 4.6 10.4 13.7 7.2 38.7 12.3 8.9 19.5 26.2 8.9 4.0 1.8 2.5 22.7 19.0 4.1 9.9 3.7 5.7 5.0 10.9 13.4 8.1 7.6 16.4 7.1 6.7 3.6 27.3 11.0 5.1 3.4 5.4 19.7 7.6 20.7 0.0 5.6 4.6 0.0 13.1 4.9 4.1 5.9 22.6 1.9 2.1 0.8 0.8 8.2 6.4 5.9 21.7 0.0 2.5 0.3 1.7 0.0 0.0 0.9 1.9 20.3 23.5 0.0 13.8 34.1 1.5 22.7 0.4 21.6 2.2 0.7 0.0 20.2 0.5 0.8 5.2 11.1 6.5 1.2 1.7 0.1 0.0 0.4 3.7 3.9 0.7 0.2 6.2 1.0 1.2 8.7 0.1 4.1 2.1 6.0 0.4 8.0 6.5 7.9 4.0 4.8 79.0 0.0 0.1 2.4 0.8 13.1 0.1 1.0 0.2 1.2 0.3 0.0 0.2 1.5 0.6 0.0 10.6 0.1 1.7 0.1 0.1 0.2 12.0 29.1 14.4 12.5 10.4 13.7 19.5 26.2 19.0 16.4 27.3 20.7 35.8 105.8 9.3 71.5 21.1 29.7 5.9 6.3 61.5 18.4 4.6 7.0 8.9 22.8 11.7 11.0 47.9 31.1 2.4 8.4 0.0 4.5 1.9 17.1 76.0 18.7 9.1 1.3 8.1 1.5 6.9 44.0 14.3 29.4 46.9 3.6 31.4 175.5 75.0 0.0 22.5 2.2 8.2 169.1 109.5 2.5 31.1 74.8 26.6 38.4 6.4 0.5 0.0 57.8 7.7 4.9 5.0 28.2 2.2 2.6 0.1 18.0 8.4 6.7 46.0 24.3 23.4 1.0 1.8 17.1 19.5 8.9 6.5 39.5 3.2 13.3 ABCA12 "DKFZP434G232, ICR2B, LI2" ENSG00000144452 "ATP binding cassette subfamily A member 12" Q86UK0 2 214931542-215138626 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 5.7;skin 1: 20.7" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 12.9;Suprabasal keratinocytes: 38.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "hTCEpi: 38.7;SK-BR-3: 18.3;T-47d: 9.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "cerebral cortex: 1.0;hippocampal formation: 1.1" HPA078239 Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Vesicles, Plasma membrane" "Nucleoli, Cytosol" "HPA078239: AB_2732373" "unprognostic (6.12e-2)" "unprognostic (4.33e-2)" "unprognostic (1.43e-1)" "unprognostic (2.03e-1)" "unprognostic (2.49e-1)" "unprognostic (2.13e-1)" "unprognostic (2.09e-4)" "unprognostic (6.52e-3)" "unprognostic (3.75e-2)" "unprognostic (1.11e-1)" "unprognostic (6.35e-4)" "unprognostic (2.50e-2)" "unprognostic (7.69e-2)" "unprognostic (5.92e-2)" "unprognostic (2.64e-2)" "unprognostic (2.36e-1)" "unprognostic (5.08e-2)" 0.0 0.0 0.0 0.1 0.1 0.0 5.7 0.0 0.1 1.3 0.0 0.3 0.0 0.0 0.7 1.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.3 0.2 0.2 0.0 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 2.8 0.3 3.9 0.1 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 38.7 0.0 2.8 0.0 0.0 0.0 0.0 0.2 0.2 0.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.4 0.5 0.1 2.7 0.0 18.3 0.0 0.2 9.7 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.3 0.0 12.9 0.9 6.0 0.0 0.2 1.0 0.5 0.5 0.0 5.1 0.0 0.0 1.1 0.0 3.0 0.0 0.1 2.2 2.6 0.3 0.1 0.0 0.0 1.4 0.0 2.7 0.1 1.5 3.7 0.0 0.5 0.0 0.0 0.4 1.7 2.9 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.5 0.6 1.9 0.0 0.7 0.0 1.0 0.0 0.1 3.1 0.2 0.0 0.0 0.2 0.7 0.4 2.2 38.6 3.4 0.0 0.1 0.9 2.7 ABCA13 "FLJ33876, FLJ33951" ENSG00000179869 "ATP binding cassette subfamily A member 13" 7 48171458-48647497 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 15 "bone marrow: 44.6" "Group enriched" "Detected in some" 5 "Basal respiratory cells: 33.8;Club cells: 25.8;Respiratory ciliated cells: 101.5" "Cancer enhanced" "Detected in some" "lung cancer: 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 5.8;LHCN-M2: 2.4;U-2 OS: 6.4;U-266/84: 2.9" "Not detected" "Not detected" HPA063601 Approved Vesicles,Centrosome,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "Centrosome, Cytosol" "HPA063601: AB_2685057" "unprognostic (8.97e-2)" "unprognostic (5.82e-2)" "unprognostic (3.18e-1)" "unprognostic (6.48e-2)" "unprognostic (2.65e-2)" "unprognostic (5.59e-2)" "unprognostic (5.19e-2)" "unprognostic (2.33e-3)" "unprognostic (1.90e-1)" "unprognostic (1.86e-3)" "unprognostic (6.03e-3)" "unprognostic (3.26e-1)" "unprognostic (1.89e-2)" "unprognostic (1.99e-1)" "unprognostic (1.25e-1)" "unprognostic (2.04e-1)" "unprognostic (3.62e-2)" 0.0 0.0 0.1 0.1 0.3 44.6 0.6 0.1 0.2 0.3 0.3 0.2 0.2 0.1 1.1 1.2 1.2 0.3 0.0 0.3 0.1 0.9 0.3 1.3 0.1 0.1 0.3 0.0 0.7 0.0 1.2 0.0 0.1 0.0 0.3 0.4 0.9 0.2 0.0 0.9 0.1 0.0 0.0 0.5 0.0 1.6 0.1 0.6 3.0 0.0 1.7 0.1 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.2 0.7 0.0 0.2 0.0 0.0 0.0 1.3 0.0 1.2 0.3 0.7 1.4 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.5 0.0 0.2 0.0 0.1 2.4 0.0 0.0 0.0 0.1 0.0 1.3 0.2 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.4 6.4 0.3 1.0 1.9 2.9 0.0 0.8 0.3 0.2 0.9 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.1 0.2 0.3 0.1 0.1 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.5 0.3 0.0 0.0 0.1 33.8 0.0 0.0 1.2 0.3 10.5 0.0 25.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 10.2 1.8 0.5 0.2 0.0 0.8 0.6 0.4 0.0 0.4 0.0 0.9 0.0 0.0 0.0 0.9 0.2 0.0 0.5 0.2 6.1 0.0 0.0 6.1 0.0 0.4 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 101.5 0.0 0.0 0.1 1.8 3.6 3.7 1.7 0.0 0.0 0.1 0.1 0.5 0.2 ABCA2 ABC2 ENSG00000107331 "ATP binding cassette subfamily A member 2" Q9BZC7 9 137007234-137028922 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "brain: 543.0" "Cell type enriched" "Detected in many" 10 "Oligodendrocytes: 388.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 66.4" "Low region specificity" "Detected in all" HPA042886 Approved Supported Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 6: T47d - Mammary gland" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA042886: AB_2678213" "unprognostic (1.01e-2)" "unprognostic (9.21e-3)" "unprognostic (9.59e-2)" "unprognostic (6.15e-2)" "unprognostic (1.02e-1)" "unprognostic (8.08e-2)" "unprognostic (2.20e-2)" "unprognostic (1.13e-2)" "unprognostic (5.61e-3)" "unprognostic (1.76e-1)" "unprognostic (2.93e-2)" "unprognostic (2.74e-2)" "unprognostic (6.78e-3)" "unprognostic (3.14e-3)" "unprognostic (1.37e-1)" "unprognostic (2.80e-1)" "unprognostic (1.36e-1)" 9.0 6.0 90.2 4.2 269.7 6.7 6.3 194.3 189.0 5.9 0.0 7.9 3.0 4.3 4.5 3.3 6.2 5.9 9.1 92.4 101.3 7.1 7.4 6.2 4.6 284.9 211.4 3.2 9.3 13.4 23.4 3.1 255.1 7.1 2.2 2.7 8.4 4.7 7.3 6.6 6.5 2.4 135.7 9.5 11.6 2.9 204.9 2.9 15.2 3.5 1.8 5.6 5.3 543.0 8.6 9.2 4.5 18.2 11.1 11.8 7.9 9.5 3.8 4.2 1.5 2.8 10.3 0.4 26.2 10.2 4.1 14.4 2.9 6.9 0.8 6.4 5.9 0.8 26.2 3.5 5.5 13.3 14.5 5.0 6.3 3.0 0.9 15.3 2.4 2.7 2.2 1.5 5.3 25.7 0.1 29.1 2.4 10.9 9.5 13.3 4.6 13.0 2.9 2.0 17.4 20.0 10.1 19.6 7.2 0.3 66.4 17.4 11.9 11.2 6.1 16.0 3.9 0.3 0.2 0.1 19.0 2.6 5.8 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.6 0.2 0.3 90.2 269.7 194.3 189.0 92.4 101.3 284.9 211.4 255.1 135.7 204.9 543.0 7.2 0.0 0.0 26.1 2.3 3.3 1.5 7.1 3.4 12.6 6.2 9.1 5.1 17.2 2.3 1.8 14.6 1.0 24.0 15.2 1.9 2.9 1.0 6.7 4.8 4.7 34.7 6.6 23.4 1.5 1.2 6.4 5.1 6.9 0.0 12.6 6.1 8.6 1.2 37.0 20.8 7.0 2.0 3.5 4.6 1.6 22.1 2.7 5.4 4.7 0.9 12.8 24.7 12.5 388.7 2.3 7.1 23.7 6.7 2.4 11.6 1.4 4.9 7.9 0.0 11.4 4.7 0.5 4.7 1.7 2.7 0.8 13.2 2.8 11.0 1.3 ABCB9 EST122234 ENSG00000150967 "ATP binding cassette subfamily B member 9" Q9NP78 12 122920951-122981649 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peptide transport, Protein transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.4;testis: 17.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 46.3;Inhibitory neurons: 41.7;Plasma cells: 92.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6;memory B-cell: 2.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "GAMG: 25.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033052, HPA035113, HPA035114" Approved Supported Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "CAB033052: AB_2273463, HPA035113: AB_2674470, HPA035114: AB_10601329" "unprognostic (1.47e-2)" "unprognostic (6.46e-4)" "unprognostic (3.96e-2)" "unprognostic (2.73e-1)" "prognostic unfavorable (5.65e-4)" "unprognostic (1.46e-1)" "unprognostic (2.67e-2)" "unprognostic (2.35e-1)" "unprognostic (4.08e-2)" "unprognostic (6.07e-2)" "unprognostic (2.28e-1)" "unprognostic (1.24e-1)" "unprognostic (1.37e-2)" "unprognostic (6.97e-2)" "unprognostic (1.70e-1)" "unprognostic (3.58e-3)" "unprognostic (2.71e-2)" 3.0 3.1 11.9 1.6 10.4 3.4 3.9 19.7 20.4 3.1 0.0 2.4 2.7 3.0 4.9 2.9 2.9 2.5 4.9 8.2 7.5 3.6 1.2 1.6 1.6 7.3 9.1 4.0 3.2 2.8 11.6 1.8 6.0 3.5 2.1 7.3 5.6 2.8 1.6 3.3 3.4 2.0 2.1 3.6 3.4 17.8 16.0 1.3 3.0 1.2 1.9 1.9 3.1 10.6 4.7 8.6 4.7 4.5 2.0 3.8 2.2 3.0 4.3 5.1 3.2 3.7 5.3 5.2 3.4 2.8 25.9 4.3 3.5 7.2 2.0 1.0 7.0 22.9 7.7 5.9 2.2 1.1 9.0 5.3 2.8 7.5 2.3 12.5 5.7 5.1 4.6 3.8 2.9 10.6 1.7 2.2 1.5 5.0 8.4 6.4 1.3 5.0 2.6 3.1 5.0 1.5 1.5 10.7 10.7 1.8 12.6 1.6 2.5 3.6 12.2 11.5 8.8 12.3 7.4 1.5 6.3 2.5 20.2 2.6 0.3 0.3 0.3 0.1 0.8 2.5 0.3 0.3 0.2 0.5 0.6 0.6 0.7 0.2 0.1 0.1 0.2 0.8 11.9 10.4 19.7 20.4 8.2 7.5 7.3 9.1 6.0 2.1 16.0 10.6 9.7 6.4 4.6 13.4 15.9 3.2 2.8 1.5 8.6 10.7 3.9 5.0 2.0 0.0 2.5 3.7 14.6 5.2 3.4 1.9 0.0 3.8 8.9 2.6 2.6 4.0 1.2 2.1 46.3 1.5 1.8 2.0 4.1 5.6 2.5 3.0 2.9 1.2 1.1 6.7 41.7 1.1 0.0 1.0 2.1 23.2 2.8 1.8 5.4 7.5 0.3 20.0 2.1 4.0 18.1 2.5 0.1 2.6 92.2 2.1 4.1 0.9 0.7 5.3 6.6 2.1 3.7 9.6 3.5 3.3 3.1 1.4 3.9 2.9 2.6 1.8 ABCG1 ABC8 ENSG00000160179 "ATP binding cassette subfamily G member 1" P45844 21 42199689-42297244 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 122.6;Syncytiotrophoblasts: 63.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 35.5;neutrophil: 36.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 36.6" "Cell line enhanced" "Detected in many" "hTCEpi: 25.5;JURKAT: 38.4;MCF7: 33.2;MOLT-4: 31.5;OE19: 54.9;RPMI-8226: 25.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031470, HPA031471" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus, Vesicles" "HPA031470: AB_10599188, HPA031471: AB_10600201" "unprognostic (2.89e-2)" "unprognostic (2.53e-2)" "unprognostic (9.96e-2)" "unprognostic (4.20e-3)" "unprognostic (2.87e-1)" "unprognostic (3.09e-2)" "unprognostic (5.74e-2)" "unprognostic (2.07e-1)" "unprognostic (1.54e-1)" "unprognostic (1.66e-3)" "unprognostic (3.66e-3)" "unprognostic (6.37e-2)" "prognostic favorable (7.16e-6)" "unprognostic (1.40e-2)" "unprognostic (2.00e-2)" "unprognostic (1.66e-1)" "unprognostic (2.42e-2)" 17.2 37.7 18.3 12.1 25.5 8.1 15.2 14.4 20.2 8.1 20.0 14.1 17.5 4.9 3.9 4.1 6.3 13.8 10.5 15.5 17.0 10.2 6.3 29.4 18.1 12.0 19.9 6.3 5.3 24.4 10.7 13.7 13.3 6.2 15.0 29.1 16.1 7.0 19.6 16.8 22.0 4.0 12.2 31.2 15.9 1.1 20.3 18.9 8.5 6.2 12.1 12.9 5.0 24.7 0.0 6.0 4.6 2.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 3.1 1.9 0.8 0.0 0.7 0.9 0.0 8.8 0.0 8.5 0.5 10.2 19.2 0.0 17.4 0.0 0.4 2.0 25.5 0.1 3.9 0.0 18.2 38.4 0.0 0.1 0.0 33.2 31.5 0.2 1.4 54.9 10.3 0.4 0.0 25.8 0.0 2.8 22.3 5.8 3.7 13.5 0.0 0.4 5.7 0.9 11.8 0.0 4.7 0.1 0.0 13.1 4.2 0.0 0.1 3.3 0.5 1.7 1.7 35.5 3.0 0.5 5.6 5.5 6.1 6.0 1.1 7.0 5.8 5.0 36.6 7.4 0.3 2.5 7.4 2.1 18.3 25.5 14.4 20.2 15.5 17.0 12.0 19.9 13.3 12.2 20.3 24.7 38.2 6.4 8.2 0.3 21.3 8.9 6.9 3.2 5.7 48.4 4.1 6.9 9.5 4.3 5.9 25.8 50.1 7.0 7.0 33.4 3.9 2.6 4.5 21.6 6.3 33.8 3.5 5.7 13.2 1.2 1.8 7.5 11.2 45.3 0.0 1.2 42.8 0.6 16.0 11.8 17.8 12.1 8.2 44.5 23.4 7.6 0.3 20.9 3.6 7.5 4.3 16.1 3.1 43.2 40.6 2.3 8.3 1.9 4.0 3.0 36.6 1.1 4.5 122.6 6.6 1.6 3.5 0.6 0.5 1.0 6.7 63.1 21.4 10.4 1.1 9.1 ABCG8 GBD4 ENSG00000143921 "ATP binding cassette subfamily G member 8" Q9H221 2 43831942-43882988 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 40 "intestine: 31.5;liver: 63.4" "Group enriched" "Detected in some" 4 "Hepatocytes: 32.0;Proximal enterocytes: 13.8" "Cancer enriched" "Detected in some" 30 "liver cancer: 21.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 44 "Hep G2: 5.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA019556 Uncertain Approved Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA019556: AB_1844444" "unprognostic (1.99e-1)" "unprognostic (4.49e-1)" "unprognostic (3.22e-1)" "unprognostic (1.37e-1)" "unprognostic (3.09e-2)" "unprognostic (2.43e-1)" "unprognostic (1.99e-3)" "unprognostic (1.27e-1)" "unprognostic (6.28e-1)" "unprognostic (6.14e-3)" "unprognostic (4.69e-1)" "unprognostic (1.76e-1)" "unprognostic (2.68e-1)" "unprognostic (7.86e-3)" "unprognostic (5.03e-1)" "unprognostic (1.50e-1)" 0.1 0.0 0.4 0.1 0.3 0.1 0.0 0.2 1.1 0.0 0.0 0.2 29.8 0.1 0.0 0.0 0.2 0.9 0.0 0.2 0.4 0.3 63.4 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.1 31.5 0.0 0.0 0.1 0.3 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 1.1 0.2 0.4 0.3 0.1 0.4 0.0 0.7 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 2.8 0.6 1.8 0.0 0.0 0.1 0.0 1.9 0.1 0.0 0.2 0.7 0.6 0.0 2.7 3.6 0.0 0.0 0.2 0.0 0.5 0.0 0.2 0.4 32.0 0.0 0.0 2.8 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 5.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.2 0.0 ABHD14A "DKFZP564O243, DORZ1" ENSG00000248487 "Abhydrolase domain containing 14A" Q9BUJ0 3 51971426-51981199 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 124.3;Rod photoreceptor cells: 115.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 79.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038153, HPA056913" Approved Enhanced Vesicles NA NA 420000 "Cluster 20: T-cells - T-cell receptor" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA038153: AB_2675868, HPA056913: AB_2683275" "unprognostic (4.15e-3)" "unprognostic (6.73e-2)" "unprognostic (1.98e-1)" "unprognostic (3.34e-2)" "unprognostic (2.71e-1)" "unprognostic (1.08e-2)" "unprognostic (8.92e-2)" "prognostic favorable (4.72e-4)" "unprognostic (3.96e-1)" "unprognostic (2.46e-2)" "unprognostic (5.52e-3)" "unprognostic (1.51e-2)" "unprognostic (1.97e-2)" "unprognostic (9.74e-2)" "unprognostic (2.17e-1)" "unprognostic (1.33e-1)" "unprognostic (1.30e-2)" 23.5 48.6 65.2 8.3 64.5 13.5 18.4 72.3 78.0 25.1 67.6 18.1 10.6 15.0 28.3 8.4 24.2 12.1 36.1 64.8 69.3 35.3 26.1 14.3 11.4 59.6 60.0 27.1 26.6 27.1 49.6 8.9 59.7 19.0 6.9 43.5 23.2 14.5 34.8 7.6 12.9 7.5 59.2 14.6 17.7 13.2 69.4 11.5 32.8 39.1 8.4 19.4 16.7 59.8 6.9 12.9 8.2 24.7 79.8 39.9 4.5 9.0 14.8 10.6 14.3 14.8 27.0 7.8 6.0 22.4 12.1 6.2 9.0 10.0 3.4 25.1 10.0 22.7 37.4 50.0 22.4 31.4 29.0 37.9 6.6 9.0 4.6 23.7 13.8 14.6 9.3 25.4 16.8 7.8 14.5 31.8 4.7 32.4 30.4 10.3 4.2 73.9 20.7 10.6 16.8 26.1 22.5 4.7 13.5 1.7 7.1 33.7 8.2 9.6 10.4 23.4 10.7 37.0 37.4 6.6 18.1 49.6 14.1 6.9 20.3 15.2 94.0 12.7 96.5 49.0 80.9 83.5 36.2 41.5 73.7 79.0 2.1 45.5 8.6 46.0 88.4 54.9 65.2 64.5 72.3 78.0 64.8 69.3 59.6 60.0 59.7 59.2 69.4 59.8 15.9 6.4 21.7 0.0 20.2 9.7 25.1 29.0 4.0 90.8 21.0 22.9 24.3 20.0 20.8 33.1 25.0 10.3 29.6 7.1 33.2 15.5 4.7 23.5 18.0 14.1 40.2 2.5 0.0 12.4 15.3 36.9 4.6 14.9 15.2 12.8 17.2 16.2 29.3 58.9 0.0 14.0 24.4 14.2 18.5 24.9 88.0 14.6 12.4 0.0 7.4 59.9 41.2 0.0 0.0 17.1 5.6 33.1 16.3 17.0 13.8 124.3 29.5 115.2 19.7 24.7 16.8 18.2 57.8 1.8 5.5 4.9 28.9 20.6 15.3 19.5 ABHD14A-ACY1 ENSG00000114786 "ABHD14A-ACY1 readthrough" 3 51974706-51989183 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 4.8;Collecting duct cells: 5.5;Distal tubular cells: 3.9;Proximal tubular cells: 16.8;Theca cells: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA036174, HPA036175, HPA038153" Approved Uncertain Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA036174: AB_2674988, HPA036175: AB_2674989, HPA038153: AB_2675868" "unprognostic (8.40e-2)" "unprognostic (1.37e-1)" "unprognostic (4.90e-2)" "unprognostic (7.22e-3)" "unprognostic (3.83e-2)" "unprognostic (1.43e-1)" "unprognostic (1.82e-1)" "unprognostic (1.35e-1)" "unprognostic (6.23e-2)" "unprognostic (2.71e-1)" "unprognostic (1.10e-1)" "unprognostic (1.29e-2)" "unprognostic (9.02e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-1)" "unprognostic (1.02e-1)" "unprognostic (7.11e-4)" 0.5 0.8 0.1 0.1 0.1 0.0 0.4 0.6 0.4 0.2 0.2 0.2 0.0 0.6 0.0 0.2 0.5 0.1 0.2 0.1 0.2 0.3 0.3 0.2 0.0 0.2 0.1 0.1 0.3 0.0 0.4 0.0 0.2 0.2 0.0 0.0 0.4 0.0 0.7 0.2 0.2 0.0 0.2 0.2 0.4 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.1 0.0 0.5 0.2 0.0 0.0 0.4 0.1 0.1 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.2 0.3 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.1 0.4 0.5 1.2 0.9 0.8 0.6 0.7 1.1 1.0 0.5 0.7 1.0 0.0 1.1 0.6 0.6 1.0 0.5 0.1 0.1 0.6 0.4 0.1 0.2 0.2 0.1 0.2 0.2 0.1 0.2 1.4 0.0 4.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 3.2 3.2 0.0 0.0 1.8 5.5 0.0 0.0 0.9 0.1 3.9 1.5 0.0 0.4 1.4 0.6 0.0 0.8 1.0 1.2 0.0 1.0 2.0 0.8 0.0 1.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.0 0.5 1.2 2.0 0.0 0.0 0.0 0.0 0.2 16.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.8 6.3 0.0 0.0 ABHD17A "C19orf27, FAM108A1, MGC5244" ENSG00000129968 "Abhydrolase domain containing 17A, depalmitoylase" Q96GS6 19 1876810-1885496 "Enzymes, Predicted intracellular proteins, Transporters" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 338.2;NK-cells: 383.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 90.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043270, HPA047226, HPA069225" Uncertain Approved "Nuclear speckles,Vesicles" NA NA "Cluster 37: B-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Nuclear speckles" "HPA043270: AB_2678401, HPA047226: AB_2679991, HPA069225: " "unprognostic (3.77e-2)" "unprognostic (1.85e-1)" "unprognostic (3.57e-2)" "prognostic favorable (1.73e-4)" "unprognostic (3.70e-2)" "prognostic favorable (6.46e-4)" "unprognostic (1.69e-2)" "unprognostic (1.92e-2)" "unprognostic (5.09e-1)" "unprognostic (1.44e-1)" "prognostic favorable (1.76e-5)" "unprognostic (1.29e-2)" "unprognostic (1.85e-3)" "unprognostic (1.17e-1)" "unprognostic (2.71e-1)" "unprognostic (3.17e-1)" "unprognostic (1.60e-2)" 49.8 51.5 61.3 8.8 50.0 13.4 44.1 53.0 104.9 43.9 16.0 50.3 13.6 46.5 2.1 63.6 42.3 4.1 79.9 70.8 36.6 47.3 42.9 52.7 10.7 66.9 54.2 41.7 42.9 7.5 45.1 11.6 60.6 52.5 2.0 1.9 40.4 8.2 56.9 73.3 41.8 3.2 56.3 69.3 45.4 33.4 61.4 8.6 43.0 10.7 3.9 45.3 45.9 56.9 43.0 14.7 6.0 16.7 7.8 9.6 32.5 28.6 8.8 8.4 7.7 7.4 7.5 21.1 11.3 8.3 1.9 26.9 3.0 11.8 1.2 48.9 61.8 15.9 6.7 19.2 10.7 16.4 50.9 10.5 8.8 4.9 3.4 5.5 16.2 20.6 27.6 23.9 6.1 24.1 28.3 31.0 31.2 8.3 32.3 32.8 14.3 32.0 5.9 9.4 19.4 43.9 14.8 16.0 29.8 2.4 16.6 28.3 31.3 9.4 21.4 38.1 28.3 90.8 58.8 18.2 20.6 21.0 15.5 1.6 1.0 4.2 5.2 0.6 3.8 3.7 2.3 3.5 1.0 1.4 2.5 2.7 1.1 3.1 0.6 1.0 2.4 0.9 61.3 50.0 53.0 104.9 70.8 36.6 66.9 54.2 60.6 56.3 61.4 56.9 125.3 3.2 5.8 13.4 35.6 32.2 21.5 10.4 12.5 41.2 43.9 35.6 4.0 24.3 12.1 14.7 39.6 77.8 338.2 61.8 9.8 31.0 6.4 28.4 43.7 67.6 30.5 22.3 12.8 37.8 43.2 29.8 29.6 37.8 10.2 31.6 65.0 21.5 66.3 55.5 12.5 34.9 12.2 36.1 28.7 6.4 30.1 42.8 26.6 19.7 35.0 66.0 383.1 5.0 63.1 42.7 31.9 36.5 58.7 25.9 38.6 19.5 7.5 35.5 13.1 31.0 44.1 16.3 20.7 21.2 45.9 65.7 117.1 66.1 34.0 32.3 ABHD3 LABH3 ENSG00000158201 "Abhydrolase domain containing 3, phospholipase" Q8WU67 18 21650901-21704780 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 187.7;Paneth cells: 126.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "REH: 209.6;RPMI-8226: 233.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010729 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" Vesicles "HPA010729: AB_1844449" "unprognostic (1.46e-1)" "unprognostic (4.61e-2)" "unprognostic (2.37e-2)" "unprognostic (3.52e-1)" "unprognostic (8.46e-2)" "unprognostic (3.14e-3)" "unprognostic (3.54e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (8.52e-4)" "unprognostic (6.21e-2)" "unprognostic (1.98e-1)" "unprognostic (6.37e-2)" "unprognostic (1.73e-1)" "unprognostic (2.15e-2)" "unprognostic (1.00e-1)" "unprognostic (3.98e-2)" "unprognostic (4.58e-2)" 17.1 7.3 13.3 25.2 13.8 17.6 15.7 16.8 21.9 12.6 23.2 63.5 44.1 8.1 9.1 18.1 12.0 20.8 7.5 13.2 14.0 14.5 39.3 15.7 29.8 14.2 15.6 12.5 12.3 16.0 11.4 19.8 16.2 11.1 65.7 5.8 14.5 6.2 14.4 6.3 56.3 9.7 13.2 24.0 35.6 6.3 16.2 21.4 22.9 7.9 25.8 15.3 12.8 15.9 29.0 20.6 19.8 12.7 12.3 8.2 0.1 18.6 7.6 13.1 17.6 21.6 29.1 82.3 33.2 6.2 58.6 93.6 32.5 15.3 18.1 52.1 21.9 9.0 35.7 37.5 18.7 39.6 28.9 7.3 17.7 19.2 8.8 6.5 8.7 28.0 23.4 47.9 11.6 11.7 38.5 43.6 9.7 92.1 47.8 209.6 15.0 233.5 36.4 27.6 16.6 7.5 42.5 37.6 11.2 21.3 11.7 68.9 6.9 12.7 18.2 22.6 29.3 53.1 37.5 84.9 16.1 50.9 29.4 89.3 24.7 29.3 25.3 44.4 19.8 16.2 22.7 24.8 15.2 12.6 18.2 23.2 81.6 18.6 61.8 10.2 44.9 24.3 13.3 13.8 16.8 21.9 13.2 14.0 14.2 15.6 16.2 13.2 16.2 15.9 8.4 9.6 9.3 42.4 22.8 33.4 40.8 21.6 18.2 14.3 12.9 6.2 4.6 40.0 25.4 3.7 47.9 30.6 24.4 187.7 1.9 52.9 4.1 32.6 9.9 9.5 36.4 10.3 27.2 27.5 22.7 10.6 32.1 49.4 11.4 1.2 10.4 31.6 68.5 0.0 30.9 57.9 52.9 31.9 47.2 1.5 7.5 26.4 32.0 33.7 29.6 7.8 26.8 17.1 10.7 51.1 126.6 6.4 45.5 32.0 93.8 8.8 40.8 15.7 13.1 6.8 13.2 4.1 9.7 22.4 15.2 94.3 38.3 5.4 36.8 36.8 ABHD5 "CGI-58, NCIE2" ENSG00000011198 "Abhydrolase domain containing 5, lysophosphatidic acid acyltransferase" Q8WTS1 3 43690108-43734371 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Cataract, Deafness, Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 205.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 67.8;neutrophil: 42.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 67.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020685, HPA035851, HPA035852" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Cytosol" Nucleoplasm "CAB020685: , HPA035851: AB_10671942, HPA035852: AB_10672073" "unprognostic (2.58e-1)" "unprognostic (2.73e-1)" "prognostic favorable (8.89e-4)" "unprognostic (1.07e-1)" "unprognostic (1.75e-2)" "unprognostic (2.26e-1)" "unprognostic (6.13e-2)" "unprognostic (2.40e-2)" "unprognostic (5.33e-2)" "unprognostic (3.50e-3)" "unprognostic (2.56e-2)" "unprognostic (4.13e-3)" "prognostic favorable (9.17e-5)" "unprognostic (2.48e-1)" "unprognostic (8.87e-2)" "unprognostic (4.18e-2)" "unprognostic (4.18e-2)" 38.8 12.5 6.7 8.5 8.6 39.6 27.9 10.5 8.9 9.8 6.0 12.3 9.9 5.7 4.1 31.1 5.1 11.6 13.4 6.8 7.4 12.0 21.7 16.4 3.4 9.2 8.2 4.6 16.0 12.2 5.6 10.2 9.1 7.1 7.5 6.3 27.4 8.4 15.0 38.0 10.5 9.3 9.3 9.4 12.1 10.8 8.4 6.8 15.5 18.5 7.9 16.7 16.9 11.9 18.9 6.8 8.2 9.7 32.0 12.8 17.1 77.4 27.1 18.8 14.9 9.4 6.4 16.2 10.9 23.2 15.8 5.8 16.5 18.5 22.6 58.4 13.2 36.6 24.4 7.5 15.7 9.2 13.2 13.0 64.6 31.3 28.5 18.8 33.3 10.8 23.9 14.2 46.9 11.0 7.6 6.9 22.8 16.7 20.4 3.1 24.1 8.6 27.9 40.4 10.6 13.6 36.9 20.5 9.8 9.8 18.9 8.9 19.3 18.1 13.6 35.0 34.5 11.1 34.0 7.7 20.3 17.3 16.0 67.8 14.7 9.5 2.3 7.9 1.7 3.5 1.7 2.7 6.8 4.0 1.6 2.5 42.5 2.0 5.7 1.9 4.8 5.3 6.7 8.6 10.5 8.9 6.8 7.4 9.2 8.2 9.1 9.3 8.4 11.9 117.5 25.6 51.8 12.7 44.8 39.9 27.5 25.9 88.8 11.9 149.9 116.2 10.3 14.3 49.6 27.6 27.1 16.7 80.3 65.0 33.2 57.5 19.5 47.5 49.0 34.6 36.2 69.0 24.1 61.5 24.9 53.7 67.8 114.0 16.5 8.8 18.2 12.7 18.0 3.3 24.1 23.7 34.6 44.1 17.4 17.1 5.3 79.8 7.2 11.2 35.9 11.0 12.3 18.1 28.8 75.2 49.8 5.7 41.8 25.5 98.5 39.8 19.1 17.4 0.0 32.0 46.4 47.3 41.9 111.7 40.9 205.4 42.6 15.2 21.9 71.6 ABHD6 ENSG00000163686 "Abhydrolase domain containing 6, acylglycerol lipase" Q9BV23 3 58237532-58295693 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 64.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 60.6;Oligodendrocytes: 88.6;Proximal enterocytes: 55.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017283, HPA073225" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 45: Intestine - Brush border" "Cluster 3: HMC-1 - Innate immune response" "Cluster 2: Hepatocytes - Metabolism" Vesicles Nucleoplasm "HPA017283: AB_1844452, HPA073225: AB_2686583" "unprognostic (4.20e-2)" "unprognostic (7.92e-2)" "prognostic favorable (1.13e-4)" "unprognostic (2.35e-2)" "unprognostic (1.16e-2)" "unprognostic (3.00e-1)" "unprognostic (5.45e-2)" "unprognostic (1.15e-2)" "unprognostic (9.54e-2)" "unprognostic (1.11e-3)" "unprognostic (1.34e-2)" "unprognostic (1.94e-1)" "prognostic favorable (1.11e-11)" "unprognostic (1.94e-1)" "unprognostic (2.41e-1)" "unprognostic (2.72e-1)" "unprognostic (6.31e-2)" 12.2 12.9 24.0 6.4 33.9 0.9 8.9 34.1 32.4 4.4 19.4 12.7 39.5 6.1 14.7 6.4 9.1 5.8 5.7 31.6 26.9 35.6 64.9 8.5 8.0 31.7 32.3 5.0 2.7 8.9 16.6 6.4 31.7 5.5 11.1 9.2 4.0 14.3 4.6 25.5 52.3 9.2 28.8 35.0 12.9 3.9 35.5 5.5 9.1 5.4 7.6 5.8 5.9 49.8 3.5 12.0 1.8 8.5 23.2 4.2 21.2 8.9 8.1 9.2 12.5 6.9 4.8 6.6 0.8 4.7 28.5 9.9 8.3 3.9 8.4 11.3 4.2 5.7 8.1 9.7 7.8 1.7 28.1 3.9 18.4 8.8 3.8 10.6 5.0 10.6 6.8 15.0 7.2 2.6 11.7 0.7 6.1 28.5 27.3 4.2 3.8 14.8 14.5 4.8 10.8 4.4 9.9 5.1 19.0 3.7 3.6 4.5 5.8 6.6 7.0 16.6 10.8 4.2 13.5 0.3 17.1 16.9 9.3 0.0 2.2 1.7 1.6 7.4 1.5 3.6 0.9 1.9 3.7 2.5 0.9 1.1 0.0 0.7 5.2 5.4 1.2 1.0 24.0 33.9 34.1 32.4 31.6 26.9 31.7 32.3 31.7 28.8 35.5 49.8 27.1 0.0 1.8 11.4 13.6 8.7 3.0 2.7 6.2 13.3 2.1 1.5 5.6 5.7 4.9 3.7 4.2 2.0 7.7 11.2 1.9 3.0 1.0 9.8 7.9 14.1 0.0 5.7 33.6 1.9 0.9 2.9 7.7 1.5 11.4 10.1 21.4 60.6 8.9 15.2 34.3 4.0 0.0 16.7 20.0 0.7 6.8 12.1 3.6 11.2 11.5 11.2 6.2 37.7 88.6 1.9 1.4 8.2 2.0 1.8 55.1 17.4 13.8 3.3 0.0 2.9 3.9 0.5 2.2 6.9 24.6 0.5 5.1 16.0 5.8 2.0 ABI2 "ABI-2, ABI2B, AblBP3, AIP-1, argBPIA, SSH3BP2" ENSG00000138443 "Abl interactor 2" Q9NYB9 2 203328280-203447728 "Predicted intracellular proteins" "Host-virus interaction, Neurogenesis" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070567 Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Vesicles, Cytosol" "HPA070567: AB_2686281" "unprognostic (5.26e-3)" "unprognostic (5.26e-3)" "unprognostic (1.86e-1)" "unprognostic (4.11e-3)" "unprognostic (2.13e-1)" "unprognostic (1.97e-2)" "unprognostic (1.81e-3)" "unprognostic (7.05e-2)" "unprognostic (8.03e-2)" "unprognostic (8.56e-3)" "unprognostic (6.19e-3)" "unprognostic (1.95e-1)" "unprognostic (4.47e-2)" "unprognostic (4.24e-2)" "unprognostic (2.94e-1)" "unprognostic (9.21e-2)" "unprognostic (1.73e-1)" 10.5 13.2 31.0 9.5 41.9 3.3 15.2 22.9 38.4 19.0 10.0 18.7 5.7 28.0 18.7 11.9 22.5 13.4 32.7 40.4 33.0 20.9 7.4 16.1 8.2 16.3 24.1 27.9 7.5 20.4 20.5 19.4 17.3 18.7 10.7 30.0 8.6 23.0 7.4 7.6 8.9 25.2 21.3 12.9 9.3 27.5 36.0 22.2 26.5 15.8 8.7 14.6 11.9 22.5 19.3 29.4 102.5 64.4 23.9 40.5 22.6 33.0 29.0 27.9 32.2 27.3 35.5 0.0 22.0 39.0 38.8 20.9 47.1 34.6 54.8 9.5 27.4 47.9 30.9 21.4 36.3 20.6 21.1 28.8 16.5 51.2 39.5 80.5 52.6 54.1 34.7 41.8 49.7 35.0 52.8 20.4 53.5 18.2 64.8 34.5 51.4 3.5 29.3 19.6 43.2 55.3 6.2 19.2 37.4 76.8 25.0 23.9 39.9 50.4 43.0 27.8 36.2 29.3 28.7 26.6 54.7 8.5 33.2 0.2 1.4 0.0 3.3 1.6 3.6 1.4 3.7 3.7 4.0 1.3 4.4 3.9 0.2 3.9 3.8 12.7 4.4 3.2 31.0 41.9 22.9 38.4 40.4 33.0 16.3 24.1 17.3 21.3 36.0 22.5 39.7 54.5 26.5 123.4 14.7 30.1 55.7 37.7 34.1 111.9 39.5 38.7 56.7 28.6 32.8 53.3 162.6 23.7 33.1 10.1 33.2 24.3 128.2 62.3 68.4 43.6 49.2 30.3 201.3 13.1 15.7 54.1 25.0 72.3 15.8 100.0 65.7 12.3 16.7 102.6 128.6 10.9 20.3 11.4 62.3 81.6 46.6 22.1 49.8 57.1 18.6 67.6 26.8 114.1 94.2 15.5 19.4 63.2 18.3 44.2 11.1 38.5 83.1 89.6 26.3 70.5 67.9 89.0 52.4 22.0 26.1 19.7 21.7 69.9 17.0 37.5 ABL2 "ABLL, ARG" ENSG00000143322 "ABL proto-oncogene 2, non-receptor tyrosine kinase" P42684 1 179099330-179229684 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 166.8;Langerhans cells: 188.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "hTERT-HME1: 73.5;TIME: 70.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001866, CAB017106, HPA072754" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" Nucleoplasm Vesicles "CAB017106: , HPA001866: AB_1078082, HPA072754: AB_2732212" "unprognostic (3.05e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (1.07e-1)" "unprognostic (4.71e-2)" "unprognostic (9.45e-2)" "unprognostic (8.23e-3)" "unprognostic (1.91e-2)" "unprognostic (4.81e-3)" "unprognostic (1.26e-1)" "unprognostic (6.98e-2)" "unprognostic (1.12e-1)" "unprognostic (3.73e-1)" "prognostic unfavorable (1.78e-7)" "unprognostic (4.76e-2)" "unprognostic (4.14e-2)" "unprognostic (6.08e-2)" "prognostic unfavorable (8.40e-4)" 9.3 3.2 5.9 4.9 6.7 2.7 5.7 6.1 6.1 5.4 2.0 4.6 2.8 3.7 2.7 2.5 3.2 11.8 3.9 7.4 5.0 3.6 2.7 6.5 2.7 3.8 4.4 3.5 5.7 4.2 3.8 4.1 3.9 3.5 3.3 9.2 3.5 2.6 3.1 4.2 3.2 4.5 3.0 2.7 3.7 4.4 5.6 4.1 3.8 4.2 2.5 6.4 4.0 4.8 24.2 13.1 8.7 5.8 7.3 16.8 5.3 26.3 21.6 31.9 23.1 9.9 7.2 13.7 18.9 19.2 21.7 11.0 12.6 9.1 44.6 8.5 11.4 6.7 12.4 4.9 13.3 7.5 2.1 15.6 11.6 45.3 73.5 13.9 36.2 7.0 16.1 3.8 42.6 6.5 5.9 4.0 8.3 5.0 4.3 8.6 14.4 6.5 10.8 4.0 5.2 11.9 22.0 7.0 53.8 13.2 6.2 6.4 70.7 33.3 24.5 15.7 42.8 7.0 9.3 14.1 15.6 4.0 32.4 1.4 0.3 0.0 0.5 0.1 0.2 0.5 0.3 0.3 0.2 0.7 0.4 0.5 0.6 0.5 0.1 0.5 0.2 0.1 5.9 6.7 6.1 6.1 7.4 5.0 3.8 4.4 3.9 3.0 5.6 4.8 33.5 22.4 24.0 44.1 14.4 46.9 43.6 16.3 12.5 40.0 18.7 9.5 8.9 22.8 10.8 11.0 166.8 9.3 7.7 15.5 11.7 14.3 15.6 12.3 23.4 67.2 27.0 9.9 81.6 13.9 8.2 67.6 10.2 21.5 17.1 19.5 31.1 15.3 22.9 25.2 62.0 11.0 10.2 34.9 188.1 32.2 15.2 67.7 69.4 45.0 13.9 11.3 8.2 72.4 57.1 45.5 16.0 13.5 10.3 42.6 9.9 9.4 11.0 35.7 6.6 32.3 30.5 17.8 30.5 11.5 38.4 10.4 12.4 11.6 14.9 25.3 ABT1 Esf2 ENSG00000146109 "Activator of basal transcription 1" Q9ULW3 6 26596953-26600739 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077039 Approved Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA077039: AB_2732328" "unprognostic (1.32e-1)" "unprognostic (3.94e-2)" "unprognostic (3.05e-1)" "unprognostic (1.15e-3)" "unprognostic (1.77e-1)" "unprognostic (7.74e-2)" "unprognostic (2.55e-2)" "unprognostic (2.36e-2)" "unprognostic (1.85e-2)" "prognostic favorable (1.89e-4)" "unprognostic (2.30e-3)" "unprognostic (2.93e-2)" "unprognostic (7.25e-3)" "unprognostic (7.20e-2)" "unprognostic (9.57e-2)" "unprognostic (1.49e-1)" "prognostic favorable (3.80e-4)" 9.3 8.0 6.5 9.5 6.7 23.2 9.3 7.8 7.7 8.9 6.5 10.1 10.0 10.8 6.3 13.9 9.2 5.9 8.7 6.5 6.4 8.2 13.0 7.9 15.8 6.4 6.4 9.2 9.4 8.3 7.3 10.7 6.4 8.2 6.7 4.7 9.0 6.7 9.6 14.3 11.6 5.7 6.4 14.8 9.9 8.0 6.6 13.0 7.3 7.1 10.5 9.3 9.7 6.8 23.3 11.9 16.3 28.4 8.9 9.3 23.9 13.4 13.6 20.0 19.5 21.6 10.0 33.8 30.0 11.1 15.9 14.5 19.0 19.5 11.7 18.9 38.7 22.2 11.2 40.6 14.3 30.6 21.7 12.4 17.9 15.9 9.4 9.3 17.5 26.2 39.3 22.1 11.2 23.6 35.6 39.1 16.8 14.9 15.9 21.4 13.2 35.8 12.5 18.7 21.4 17.2 8.3 21.6 32.9 8.6 20.8 24.6 15.1 15.2 11.2 12.2 27.3 25.8 40.9 30.9 7.2 37.6 23.8 76.1 41.6 53.8 66.1 40.2 63.3 66.5 63.8 66.2 39.7 70.2 67.4 60.8 37.2 57.5 41.7 37.1 76.3 88.1 6.5 6.7 7.8 7.7 6.5 6.4 6.4 6.4 6.4 6.4 6.6 6.8 22.4 16.0 15.5 3.3 41.8 59.9 35.8 65.2 34.1 16.2 23.1 22.2 7.1 21.5 31.8 11.0 2.1 96.0 50.8 16.1 41.1 39.4 39.7 12.1 14.0 31.6 34.0 26.9 4.4 38.7 97.5 21.1 16.8 17.3 29.1 17.7 25.4 21.2 42.2 15.2 4.3 25.3 50.8 21.2 22.6 81.8 27.7 22.2 16.0 2.8 32.3 22.0 78.2 3.5 4.5 35.9 19.5 23.7 29.4 31.6 27.9 24.4 21.8 17.2 19.7 15.1 23.4 29.6 41.2 28.3 59.8 109.5 44.3 24.5 29.5 33.6 ABTB2 "ABTB2A, BTBD22, DKFZP586C1619" ENSG00000166016 "Ankyrin repeat and BTB domain containing 2" Q8N961 11 34150987-34358010 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.1" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 50.3;Oligodendrocytes: 126.2;Syncytiotrophoblasts: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "eosinophil: 5.0;plasmacytoid DC: 1.6" "Group enriched" "Detected in many" 14 "dendritic cells: 1.6;granulocytes: 5.0" "Cell line enhanced" "Detected in many" "SK-BR-3: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020065, HPA030699" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Vesicles "HPA020065: AB_1844459, HPA030699: AB_2673576" "unprognostic (3.00e-1)" "prognostic unfavorable (5.70e-5)" "unprognostic (2.61e-1)" "unprognostic (9.09e-2)" "unprognostic (3.17e-2)" "unprognostic (2.40e-2)" "unprognostic (1.34e-1)" "unprognostic (1.23e-2)" "unprognostic (2.04e-1)" "unprognostic (2.09e-1)" "unprognostic (1.24e-3)" "unprognostic (2.86e-1)" "prognostic favorable (3.51e-5)" "unprognostic (1.50e-1)" "unprognostic (1.42e-1)" "unprognostic (3.81e-2)" "unprognostic (6.58e-2)" 2.3 13.0 7.9 2.0 12.6 2.5 2.0 18.1 6.7 8.1 1.2 3.4 8.8 6.1 4.4 4.1 4.6 2.1 12.8 5.3 8.5 9.4 11.6 2.9 2.1 24.1 16.3 2.5 2.3 0.5 3.5 3.2 16.7 4.9 2.5 2.6 6.7 4.3 16.9 6.8 7.0 2.5 12.7 0.9 2.5 2.7 15.9 2.4 2.0 7.2 2.0 3.6 5.6 20.3 5.6 16.2 6.4 1.8 1.7 0.1 6.4 3.2 2.5 2.8 5.3 4.0 4.0 0.2 5.3 4.1 16.5 10.5 3.6 3.7 2.3 0.2 8.8 0.1 9.8 17.4 1.0 8.9 1.2 0.9 2.0 5.6 2.4 10.1 0.0 0.7 1.9 0.5 1.8 13.8 0.3 10.7 8.0 8.1 8.8 1.7 3.8 6.3 10.0 13.0 8.1 6.6 8.1 24.6 6.5 4.2 5.3 3.8 0.9 3.1 0.5 9.8 5.8 0.9 0.4 0.1 7.1 2.5 9.7 0.0 0.1 5.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.0 7.9 12.6 18.1 6.7 5.3 8.5 24.1 16.3 16.7 12.7 15.9 20.3 0.7 0.0 2.3 18.9 1.1 4.7 3.2 1.3 1.2 2.1 3.0 3.3 10.0 2.8 1.1 12.9 0.0 2.7 2.5 12.2 5.9 4.6 1.2 3.4 4.5 0.9 7.2 0.0 4.0 4.5 1.1 5.8 4.6 10.7 1.3 0.3 0.0 6.8 0.8 0.0 8.9 2.3 4.1 0.8 6.1 0.3 1.2 1.2 1.8 6.5 9.3 7.5 0.0 50.3 126.2 10.5 9.1 6.0 2.1 9.3 15.5 2.0 0.3 0.6 0.0 4.3 2.4 0.5 1.1 1.0 4.8 28.3 2.9 0.4 2.9 7.5 AC000120.3 ENSG00000285953 "Novel protein" 7 92131774-92245924 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 1.1;granulocytes: 1.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" HPA049606 Uncertain Approved Vesicles NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 1: K-562 - Erythropoiesis" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA049606: AB_2680832" 2.1 1.0 0.5 1.1 1.0 0.4 2.0 1.8 0.9 3.6 0.0 1.0 0.4 1.8 0.0 1.2 2.1 1.6 1.4 0.1 0.9 2.5 2.1 2.1 1.7 0.8 0.7 2.6 1.4 3.2 2.9 0.8 1.5 1.3 2.2 0.9 2.0 3.2 0.2 1.1 1.7 0.5 0.7 0.4 5.9 0.5 1.8 2.5 3.7 2.5 1.2 2.0 3.2 2.7 4.2 2.8 4.3 9.2 4.3 5.2 4.9 7.8 7.8 2.2 4.4 5.7 3.2 4.1 4.4 2.6 6.4 5.0 10.9 3.9 3.1 4.9 4.3 1.3 4.2 6.9 2.9 2.1 3.9 5.7 6.7 2.8 5.4 3.3 12.8 3.7 6.0 1.8 4.4 1.1 3.6 4.3 5.0 2.5 7.0 4.8 1.9 2.3 3.3 2.3 8.0 3.0 3.1 8.4 2.9 2.4 2.0 2.6 3.0 7.1 2.5 2.1 3.9 7.6 2.9 3.0 4.6 0.0 0.1 0.2 0.1 0.1 0.5 0.5 0.2 0.2 0.4 0.2 0.3 0.3 0.0 0.3 0.1 0.2 0.2 0.3 0.5 1.0 1.8 0.9 0.1 0.9 0.8 0.7 0.8 0.5 0.5 2.0 0.0 3.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC005726.1 ENSG00000258472 "Novel protein" 17 28455752-28614185 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 13.2;Club cells: 5.6;granulocytes: 6.3;Proximal tubular cells: 20.4;Respiratory ciliated cells: 5.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.0" HPA046590 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" Nucleoplasm "HPA046590: AB_2679710" "unprognostic (1.26e-2)" "unprognostic (1.82e-1)" "unprognostic (6.04e-3)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "unprognostic (2.23e-3)" "unprognostic (2.76e-3)" "unprognostic (7.25e-2)" "unprognostic (5.96e-2)" "unprognostic (4.58e-2)" "unprognostic (9.22e-3)" "unprognostic (3.17e-3)" "unprognostic (1.49e-4)" "unprognostic (1.25e-1)" "unprognostic (2.65e-1)" "unprognostic (7.50e-2)" "unprognostic (3.79e-4)" 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 9.6 13.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.3 2.4 0.0 0.0 5.6 3.7 0.0 1.7 0.5 0.0 1.9 1.2 0.0 1.7 2.4 1.4 0.0 0.0 0.0 2.0 0.8 1.6 0.0 3.2 6.3 2.6 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 20.4 5.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 5.3 1.1 1.2 0.0 0.0 AC007325.2 ENSG00000277196 "Proline dehydrogenase 1, mitochondrial" Unmapped 138082-161852 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "brain: 113.8;choroid plexus: 218.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 5.9;Distal tubular cells: 7.9;Endometrial ciliated cells: 2.5;Proximal enterocytes: 5.6;Squamous epithelial cells: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "OE19: 345.1;RPTEC TERT1: 183.1" HPA020361 Uncertain Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Mitochondria "Nucleoplasm, Vesicles" "HPA020361: AB_10963116" 2.2 0.6 83.9 0.8 83.5 0.7 3.3 75.2 113.8 1.0 218.6 1.1 28.9 0.5 0.1 6.8 1.4 0.4 9.5 90.0 76.6 12.3 6.0 18.8 1.0 87.3 82.6 0.0 0.1 0.1 0.9 72.0 0.9 1.4 1.9 0.7 2.4 10.2 32.6 33.2 0.2 74.5 0.7 0.8 1.9 85.0 5.6 4.5 24.0 6.4 1.9 72.3 0.0 8.3 0.3 2.5 5.0 0.0 1.6 0.0 0.0 0.0 0.0 5.3 1.8 0.0 0.5 0.0 0.2 10.0 18.8 0.5 0.0 0.0 0.7 0.0 0.2 0.9 3.6 0.0 0.1 0.4 18.5 0.0 1.0 0.0 0.0 0.3 0.0 0.1 0.0 1.5 0.2 0.0 17.5 345.1 0.0 0.1 0.1 0.0 183.1 0.7 0.4 0.5 0.0 6.9 1.5 18.8 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.9 83.5 75.2 113.8 90.0 76.6 87.3 82.6 72.0 74.5 85.0 72.3 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 2.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.6 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.2 2.3 0.0 0.0 0.0 0.0 0.2 0.1 AC011455.2 ENSG00000269547 "Novel protein" 19 38915404-38949855 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "A549: 1.0" "HPA052730, HPA056957" Uncertain Uncertain Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 6: T47d - Mammary gland" "Nucleoplasm, Mitochondria" Vesicles "HPA052730: AB_2681929, HPA056957: AB_2683286" "unprognostic (6.10e-2)" "unprognostic (3.79e-2)" 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.2 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC024598.1 ENSG00000285837 "Novel protein" 10 62374192-62672011 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "gallbladder: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.1;TIME: 2.5" HPA052446 Uncertain Approved Vesicles,Centrosome NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Vesicles, Centrosome" "HPA052446: AB_2681836" 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.3 0.7 0.0 0.3 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 2.5 0.3 0.7 0.1 0.4 0.0 0.0 0.1 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.1 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC092718.2 ENSG00000260643 "Novel protein" 16 81053587-81096296 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NB-4: 13.4" HPA041368 Approved Approved Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 15: Liver - Metabolism" "Cluster 14: REH - Unknown function" Vesicles "HPA041368: AB_10804001" "unprognostic (3.87e-2)" "unprognostic (1.79e-1)" "unprognostic (1.95e-1)" "unprognostic (2.12e-2)" "unprognostic (8.06e-2)" "unprognostic (1.08e-1)" "unprognostic (3.95e-2)" "unprognostic (8.11e-2)" "unprognostic (2.85e-1)" "unprognostic (2.42e-1)" "unprognostic (3.94e-2)" "unprognostic (3.19e-1)" "unprognostic (2.69e-2)" "unprognostic (2.11e-1)" "unprognostic (1.95e-1)" "unprognostic (9.56e-3)" "unprognostic (3.03e-1)" 4.4 2.9 12.8 1.1 14.6 0.5 3.5 12.7 15.5 3.1 12.8 2.5 0.3 2.5 5.0 1.7 4.8 1.3 4.8 13.5 13.6 6.5 9.6 2.6 0.9 13.8 14.4 3.2 2.9 3.2 8.1 2.8 13.8 4.5 0.8 5.7 2.6 1.7 6.4 1.2 1.4 1.6 12.1 1.3 2.2 6.2 14.0 1.3 14.2 2.9 0.6 3.6 2.7 14.1 4.1 3.1 4.8 3.4 11.1 3.9 5.0 2.1 0.9 1.8 0.3 0.3 4.7 0.6 4.1 0.9 4.1 3.3 3.0 1.3 2.7 1.4 5.3 0.7 1.5 3.1 3.9 3.0 2.6 4.7 5.9 2.8 2.6 5.3 1.9 5.9 3.6 0.3 2.5 4.5 4.1 13.4 2.3 3.2 1.7 11.7 1.0 1.9 7.3 1.6 3.8 3.7 2.4 1.0 4.1 5.1 1.1 4.7 2.1 0.8 1.7 2.2 1.7 2.6 3.3 5.4 2.4 2.1 2.0 0.9 0.4 0.3 1.2 0.3 1.3 1.6 0.8 0.4 1.1 1.5 1.2 0.7 0.3 1.7 0.4 1.8 0.2 1.0 12.8 14.6 12.7 15.5 13.5 13.6 13.8 14.4 13.8 12.1 14.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC092718.7 ENSG00000284512 "Novel protein" 16 81022316-81096284 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.9;testis: 6.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" HPA041368 Uncertain Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 78: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" Vesicles "HPA041368: AB_10804001" 0.1 0.2 2.7 0.3 3.5 1.1 0.2 2.9 3.5 0.2 2.1 0.1 0.1 0.3 0.2 0.1 0.2 0.1 0.1 2.4 2.5 0.2 0.2 0.1 0.2 2.9 3.0 0.3 0.2 0.3 0.3 0.2 2.8 1.3 0.0 0.7 0.1 0.1 0.1 0.2 0.1 0.0 2.7 0.1 0.1 6.5 2.8 0.0 0.5 0.0 0.0 0.1 0.1 3.9 0.4 0.2 0.6 0.5 0.1 0.0 0.5 0.8 0.1 0.1 0.0 0.4 0.6 0.6 0.3 0.2 0.3 0.9 0.0 0.0 0.1 0.1 0.4 0.3 1.0 0.6 0.0 0.6 1.1 0.2 0.0 0.1 0.0 0.3 0.0 0.7 0.3 1.0 0.0 1.3 0.6 1.4 0.6 0.2 0.4 0.5 0.4 0.1 0.0 0.3 0.9 0.2 0.6 0.3 0.1 0.3 0.4 0.2 0.1 0.5 0.6 0.4 0.3 0.5 0.3 1.2 0.2 0.3 0.2 0.3 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.3 0.1 0.2 0.2 0.2 0.1 0.4 0.3 0.1 2.7 3.5 2.9 3.5 2.4 2.5 2.9 3.0 2.8 2.7 2.8 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC118553.2 ENSG00000283761 "Novel protein" 1 99970011-100083321 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 4.1;Collecting duct cells: 1.8;Respiratory ciliated cells: 5.1" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA073681 Approved Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Vesicles "HPA073681: AB_2686625" 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.2 0.2 0.5 0.2 0.2 0.2 0.1 0.6 0.2 0.1 0.1 0.2 0.3 0.3 0.2 0.7 0.0 0.3 0.2 0.3 0.0 1.0 0.0 0.2 0.4 0.2 0.3 1.0 0.2 0.5 0.1 0.1 0.1 0.4 0.1 0.0 0.2 0.4 0.2 0.7 0.1 0.3 0.2 0.6 0.1 0.3 0.5 0.7 0.9 0.2 0.0 0.6 0.8 1.3 0.5 1.3 2.7 0.5 2.0 0.1 3.3 2.0 2.7 2.1 2.6 0.9 1.7 0.9 1.3 2.2 3.7 0.1 0.2 0.5 0.5 0.0 0.8 2.5 2.2 0.7 1.6 0.3 1.8 1.2 0.7 1.2 2.3 0.1 0.1 2.1 1.1 0.5 2.0 0.9 0.7 1.1 0.6 0.7 1.1 0.6 0.5 0.8 0.6 0.1 0.5 0.8 1.3 0.7 1.4 0.7 2.9 0.3 1.0 1.0 0.3 8.4 5.1 3.5 4.4 5.2 5.0 2.8 4.5 5.2 5.8 1.9 4.2 3.6 0.8 6.7 3.2 4.6 5.9 5.0 0.0 0.3 0.1 0.2 0.2 0.3 0.3 0.2 0.4 0.1 0.2 0.3 0.3 6.4 4.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 1.3 1.8 0.0 0.0 0.6 0.0 0.0 0.2 0.0 1.2 1.3 0.4 0.0 0.0 0.0 0.7 0.0 0.4 0.0 1.4 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.8 1.2 0.0 0.0 ACBD4 FLJ13322 ENSG00000181513 "Acyl-CoA binding domain containing 4" Q8NC06 17 45132600-45144181 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 93.0" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051772 Approved Approved Nucleoplasm,Vesicles Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Vesicles" "HPA051772: AB_2681603" "unprognostic (1.57e-2)" "unprognostic (1.45e-1)" "unprognostic (2.59e-2)" "unprognostic (1.54e-1)" "unprognostic (5.33e-3)" "unprognostic (1.60e-2)" "prognostic favorable (4.76e-4)" "unprognostic (2.27e-2)" "unprognostic (9.06e-2)" "unprognostic (4.86e-2)" "prognostic favorable (4.64e-4)" "unprognostic (8.24e-2)" "unprognostic (2.04e-3)" "unprognostic (1.97e-1)" "unprognostic (2.12e-1)" "unprognostic (1.27e-1)" "prognostic favorable (6.53e-4)" 11.1 17.2 14.4 6.3 14.1 4.1 12.9 13.9 16.6 19.1 13.1 21.2 29.9 14.4 4.0 7.1 22.3 6.6 11.8 13.4 13.9 24.6 93.0 9.6 9.9 14.2 14.0 19.3 20.0 14.5 15.8 4.3 13.4 21.6 5.7 10.3 14.1 12.2 6.8 9.0 25.9 5.7 14.5 16.2 14.7 4.2 14.2 5.4 21.1 5.1 6.4 15.7 13.6 13.2 7.9 15.4 1.9 4.2 3.5 6.4 5.1 2.9 6.1 4.7 9.2 6.0 10.8 8.4 7.4 4.3 2.8 7.3 2.6 4.8 1.9 12.2 5.9 4.2 11.3 12.0 7.5 1.6 11.1 6.4 4.6 1.7 2.4 16.1 4.6 7.7 2.7 13.1 2.3 5.3 6.0 2.1 0.3 8.3 4.2 4.8 0.5 18.8 11.8 5.1 3.1 1.4 2.1 3.1 8.9 1.0 20.1 3.0 1.7 1.2 3.6 1.8 1.8 20.4 5.9 2.6 6.8 2.1 2.0 4.4 2.3 3.5 2.9 2.6 3.2 3.7 3.4 3.2 2.0 5.0 3.7 4.3 0.5 4.0 1.7 1.3 4.3 3.2 14.4 14.1 13.9 16.6 13.4 13.9 14.2 14.0 13.4 14.5 14.2 13.2 5.7 3.2 3.0 12.4 7.8 1.9 5.9 3.9 2.8 16.6 7.4 6.9 9.7 14.3 2.6 3.7 22.9 6.3 5.9 9.6 7.9 7.3 1.4 2.0 2.7 5.3 6.0 2.1 7.2 7.1 1.3 7.3 4.6 3.6 8.2 7.4 5.0 21.8 5.3 11.8 8.5 7.8 6.1 1.9 2.6 5.0 6.8 3.1 3.6 2.8 4.5 14.7 5.2 4.5 1.9 5.6 12.5 7.5 5.2 3.1 56.8 25.6 2.6 16.8 6.6 8.7 7.7 2.5 5.2 3.1 1.8 6.3 6.4 4.4 9.1 2.8 ACBD7 "bA455B2.2, FLJ38219" ENSG00000176244 "Acyl-CoA binding domain containing 7" Q8N6N7 10 15075475-15088776 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 37.8;choroid plexus: 17.1" "Cell type enriched" "Detected in some" 5 "Astrocytes: 28.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "JURKAT: 28.7;MOLT-4: 29.2;U-698: 21.8" "Region enriched" "Detected in all" 5 "olfactory bulb: 17.6" "Low region specificity" "Detected in all" "HPA043326, HPA062478" Approved Vesicles,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Vesicles, Cytosol" "HPA043326: AB_2678429, HPA062478: AB_2684777" "unprognostic (2.15e-1)" "unprognostic (8.94e-2)" "unprognostic (7.79e-3)" "unprognostic (6.53e-3)" "unprognostic (7.30e-2)" "unprognostic (6.89e-3)" "unprognostic (1.10e-2)" "unprognostic (1.58e-1)" "unprognostic (1.32e-1)" "unprognostic (6.34e-2)" "unprognostic (3.59e-3)" "unprognostic (3.06e-1)" "unprognostic (2.18e-4)" "unprognostic (9.72e-2)" "unprognostic (2.95e-1)" "unprognostic (2.14e-1)" "unprognostic (6.90e-2)" 0.3 0.3 34.9 0.4 36.0 1.4 4.2 28.8 37.8 0.2 17.1 0.4 0.9 0.3 0.8 0.4 1.9 0.4 0.2 31.6 29.7 0.4 0.4 0.4 0.7 33.7 37.1 0.4 0.4 0.3 0.6 0.3 26.3 0.4 0.4 7.7 2.3 0.5 0.9 1.3 0.5 0.2 27.2 0.4 0.5 3.0 35.1 6.7 1.7 0.0 0.5 0.3 0.1 23.2 3.4 0.8 12.7 7.0 1.0 0.6 1.8 0.8 0.7 1.9 3.0 3.8 4.2 2.9 4.3 2.5 2.6 0.6 6.9 1.8 2.9 6.0 10.2 3.4 1.1 2.3 0.1 0.4 1.3 0.3 0.1 1.0 0.1 3.2 2.9 28.7 2.4 3.6 2.5 10.5 29.2 4.5 6.3 1.0 2.0 16.4 4.3 6.9 1.6 1.0 9.7 6.6 2.7 8.6 1.1 4.7 10.9 0.6 1.6 0.7 6.6 1.3 2.8 10.4 19.1 21.8 2.1 0.5 0.7 0.8 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.8 0.3 0.1 0.3 0.1 0.0 34.9 36.0 28.8 37.8 31.6 29.7 33.7 37.1 26.3 27.2 35.1 23.2 0.1 0.0 0.6 28.1 0.1 0.1 0.1 0.0 0.6 0.2 0.5 0.6 0.0 0.0 0.0 0.0 2.1 0.0 0.5 0.2 0.0 0.0 5.3 2.6 0.1 0.4 1.8 0.0 0.3 0.0 0.1 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 2.3 0.0 0.1 0.0 1.0 0.0 0.6 0.0 1.5 0.1 0.0 1.1 0.0 0.0 0.1 0.0 0.1 1.6 0.8 0.0 0.3 0.3 2.9 0.4 0.5 0.0 0.1 0.2 0.1 0.1 0.1 ACE "ACE1, CD143, DCP1" ENSG00000159640 "Angiotensin I converting enzyme" P12821 17 63477061-63498380 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 265.1;testis: 101.9" "Group enriched" "Detected in many" 20 "Early spermatids: 543.6;Late spermatids: 1322.9;Proximal enterocytes: 1172.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 8.1" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "ASC TERT1: 63.3;HUVEC TERT2: 33.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002426, CAB002921, HPA029298, HPA069790" Enhanced Approved Vesicles "Secreted to blood" NA NA 104000000 170000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB002426: AB_442052, CAB002921: , HPA029298: AB_10960255, HPA069790: AB_2686197" "unprognostic (4.72e-2)" "unprognostic (4.16e-1)" "unprognostic (1.93e-3)" "unprognostic (6.06e-2)" "unprognostic (2.78e-1)" "unprognostic (1.35e-2)" "unprognostic (4.37e-1)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-2)" "unprognostic (3.13e-2)" "unprognostic (2.38e-1)" "unprognostic (7.66e-2)" "unprognostic (9.07e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (2.76e-2)" 13.4 4.9 1.7 4.8 8.1 0.1 8.1 0.2 2.5 18.1 0.5 11.2 176.4 8.1 3.5 4.1 6.3 8.2 10.4 1.3 1.0 10.8 1.9 49.0 4.9 1.3 0.9 1.9 6.2 18.7 9.2 11.6 1.3 8.9 6.1 0.4 7.6 23.8 16.1 3.8 265.1 9.6 0.8 2.8 8.3 101.9 2.0 0.8 19.2 10.0 2.1 5.5 3.8 1.1 0.0 0.0 0.0 0.0 2.6 63.3 0.6 2.4 4.7 0.0 0.0 0.9 5.1 1.3 1.8 11.4 0.1 0.0 3.1 0.0 0.0 0.0 1.4 6.6 0.0 0.0 1.4 0.0 0.0 4.2 0.0 0.1 0.0 1.2 33.8 0.0 5.8 0.0 0.1 1.1 0.0 1.4 0.4 11.7 0.7 0.1 0.5 0.9 0.0 0.0 8.2 5.6 0.0 0.0 0.0 1.3 2.9 0.4 0.0 0.1 0.2 0.5 0.1 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.1 0.1 0.2 1.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.7 8.1 0.2 2.5 1.3 1.0 1.3 0.9 1.3 0.8 2.0 1.1 50.0 0.0 3.3 0.0 0.5 1.5 2.6 0.1 1.2 4.0 3.6 1.9 2.1 1.5 0.7 0.0 0.0 0.1 0.3 11.9 0.0 5.9 543.6 10.8 8.0 34.7 18.0 0.0 4.7 0.4 0.1 11.5 2.0 36.3 7.0 24.1 3.6 0.8 4.2 0.0 1.8 39.8 0.0 33.7 3.5 1322.9 4.4 13.6 3.6 4.7 0.0 1.8 0.0 1.0 0.2 0.7 40.9 2.6 0.1 4.2 1172.8 21.7 0.0 1.1 0.0 2.0 4.2 13.5 6.4 0.2 0.1 0.1 2.2 0.3 26.2 2.1 ACHE YT ENSG00000087085 "Acetylcholinesterase (Cartwright blood group)" P22303 7 100889994-100896974 "Blood group antigen proteins, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter degradation" "Blood group antigen, Hydrolase, Serine esterase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 98.2;skeletal muscle: 163.2;tongue: 48.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 86.2;Erythroid cells: 37.7;Exocrine glandular cells: 39.7;Horizontal cells: 55.5;Paneth cells: 118.3;Proximal enterocytes: 45.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 7.9;CACO-2: 13.0;K-562: 13.9;Karpas-707: 19.7;U-2 OS: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027098 Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 990000 "Cluster 80: Striated muscle - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Vesicles "HPA027098: AB_2672111" "unprognostic (2.23e-1)" "unprognostic (9.44e-2)" "unprognostic (2.71e-2)" "unprognostic (5.80e-3)" "prognostic unfavorable (5.27e-4)" "unprognostic (2.49e-1)" "unprognostic (2.54e-1)" "unprognostic (1.36e-2)" "unprognostic (2.48e-2)" "unprognostic (8.92e-2)" "unprognostic (2.65e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.88e-5)" "unprognostic (2.95e-1)" "unprognostic (2.59e-2)" "unprognostic (9.28e-2)" "unprognostic (8.38e-2)" 1.4 4.7 20.9 2.2 16.8 7.9 2.0 37.1 32.5 5.0 0.0 7.6 4.9 2.6 0.2 2.3 3.2 1.3 12.5 8.0 98.2 8.8 4.1 4.4 3.5 66.1 54.2 4.6 4.3 4.7 8.3 0.7 72.7 8.1 1.8 5.7 7.1 1.6 163.2 1.3 9.1 0.5 26.2 3.5 2.4 3.9 58.1 3.6 2.3 48.0 1.5 1.4 3.7 10.5 0.0 0.2 0.2 0.2 0.3 0.0 7.9 0.3 0.0 0.1 0.2 13.0 0.1 0.0 0.6 0.0 1.2 0.6 2.0 0.1 0.0 4.6 0.5 0.2 0.1 0.2 0.1 0.0 0.4 0.5 0.1 0.1 0.0 0.0 0.0 0.1 13.9 19.7 0.1 4.3 0.0 0.2 1.1 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.8 1.5 0.1 0.8 0.0 2.9 0.0 0.0 0.2 0.5 6.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.9 16.8 37.1 32.5 8.0 98.2 66.1 54.2 72.7 26.2 58.1 10.5 0.5 0.0 0.0 3.3 0.5 0.8 20.9 0.9 6.2 13.5 2.9 1.1 6.4 5.7 0.4 0.0 0.0 8.2 0.9 86.2 0.0 10.5 0.0 0.5 1.5 2.1 3.5 37.7 4.7 39.7 2.6 3.0 1.5 2.4 0.0 7.4 2.2 0.4 0.8 55.5 9.7 12.0 0.0 0.3 6.6 0.4 0.6 1.7 1.8 1.0 4.6 11.4 0.0 8.5 0.8 20.1 118.3 0.7 1.8 20.4 45.6 1.1 0.1 6.8 0.0 13.5 4.9 4.1 8.0 1.7 1.0 7.1 0.6 1.4 4.6 15.2 ACKR2 "CCBP2, CCR10, CCR9, CMKBR9, D6" ENSG00000144648 "Atypical chemokine receptor 2" O00590 3 42804752-42887974 "G-protein coupled receptors, Predicted membrane proteins" "Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 9.4;placenta: 16.0" "Group enriched" "Detected in many" 7 "Cytotrophoblasts: 33.0;Extravillous trophoblasts: 106.2;Syncytiotrophoblasts: 73.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 3.9;NK-cell: 1.1" "Group enriched" "Detected in many" 7 "granulocytes: 3.9;NK-cells: 1.1" "Cell line enhanced" "Detected in some" "BEWO: 51.2;HEL: 17.1;SK-BR-3: 28.0;U-937: 10.7" "Group enriched" "Detected in many" 5 "amygdala: 2.2;basal ganglia: 7.9;cerebral cortex: 4.9;hippocampal formation: 2.4" "Low region specificity" "Detected in all" "HPA013819, HPA073493" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Vesicles, Cytosol" Nucleoplasm "HPA013819: AB_1846126, HPA073493: AB_2686610" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (1.90e-2)" "unprognostic (8.15e-2)" "unprognostic (7.51e-2)" "unprognostic (1.54e-2)" "unprognostic (1.21e-3)" "unprognostic (1.74e-1)" "unprognostic (2.99e-1)" "unprognostic (6.20e-2)" "unprognostic (8.47e-2)" "unprognostic (8.45e-2)" "unprognostic (1.13e-4)" "unprognostic (5.13e-3)" "unprognostic (3.22e-1)" "unprognostic (5.58e-3)" "unprognostic (6.09e-2)" 6.7 1.0 1.5 1.0 1.0 0.7 2.8 1.5 1.3 1.7 0.9 1.9 0.9 0.9 2.8 1.6 2.3 1.3 1.3 1.0 0.5 1.5 9.4 1.6 1.1 1.4 1.4 0.4 0.9 0.4 0.5 16.0 1.3 0.6 2.1 0.7 2.2 0.4 0.6 2.6 1.1 1.1 0.6 0.7 1.1 0.8 1.1 0.4 2.9 0.9 2.1 1.8 2.3 1.3 0.1 0.0 0.2 0.4 2.4 0.2 51.2 0.1 0.0 0.0 0.0 0.5 0.1 1.2 0.1 0.1 0.2 0.4 0.0 0.2 0.1 0.1 0.2 17.1 0.4 3.1 0.1 0.2 1.9 0.5 0.5 0.0 0.1 0.0 0.1 0.5 2.2 0.4 0.3 0.3 0.0 0.2 0.1 0.7 0.2 0.1 0.0 0.1 0.7 7.5 0.3 0.1 1.3 28.0 0.1 2.9 2.8 0.3 0.1 0.1 0.1 0.2 0.1 0.6 0.1 0.1 0.1 10.7 0.1 0.4 0.1 3.9 0.2 0.2 0.0 0.1 0.0 0.0 0.2 0.3 0.1 0.1 0.4 1.1 0.3 0.1 0.0 0.1 1.5 1.0 1.5 1.3 1.0 0.5 1.4 1.4 1.3 0.6 1.1 1.3 1.0 0.0 0.0 9.8 0.1 0.1 0.1 0.3 0.0 0.7 1.2 0.3 0.8 1.5 3.3 0.0 2.1 33.0 0.3 3.0 1.9 0.1 3.0 3.7 0.8 3.3 1.8 0.0 2.0 0.0 106.2 2.1 0.0 5.9 2.5 2.5 4.6 7.0 5.3 1.7 1.2 0.6 0.0 0.6 0.4 1.8 0.3 0.4 0.0 5.6 0.1 2.6 0.0 1.0 4.5 0.8 0.5 1.2 0.1 0.4 1.6 0.5 3.4 1.0 0.0 0.4 0.3 4.8 5.4 0.0 0.0 73.6 0.5 0.5 1.1 0.6 ACKR3 "CMKOR1, CXCR7, GPR159, RDC1" ENSG00000144476 "Atypical chemokine receptor 3" P25106 2 236567787-236582354 "Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 39.6;Endothelial cells: 59.8;Fibroblasts: 171.2;Smooth muscle cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "NK-cells: 4.7;T-cells: 3.8" "Cell line enhanced" "Detected in many" "HeLa: 103.7;MCF7: 80.0;RT4: 312.3;SiHa: 97.0;U-2197: 328.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032003, HPA049718" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA032003: AB_2674107, HPA049718: AB_2680859" "unprognostic (1.65e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (2.50e-1)" "unprognostic (1.92e-3)" "unprognostic (2.10e-1)" "unprognostic (1.23e-1)" "unprognostic (7.34e-3)" "unprognostic (1.55e-2)" "unprognostic (1.85e-2)" "unprognostic (1.35e-1)" "unprognostic (9.70e-3)" "unprognostic (6.69e-2)" "prognostic unfavorable (1.76e-6)" "prognostic unfavorable (2.01e-4)" "unprognostic (9.71e-2)" "unprognostic (8.57e-3)" "prognostic unfavorable (2.93e-4)" 116.2 5.2 13.0 14.3 13.5 3.5 70.4 13.1 15.6 29.2 18.3 38.7 11.8 17.3 10.5 25.0 33.7 30.8 68.5 13.7 18.9 11.3 28.3 26.3 10.5 22.3 16.0 15.9 37.9 5.0 24.4 123.3 14.4 20.1 24.7 1.7 21.4 16.8 35.4 38.1 34.1 24.2 14.3 56.0 27.9 14.6 14.5 6.4 58.1 37.9 5.6 107.0 38.2 13.6 0.0 0.1 6.3 0.0 10.5 0.2 44.9 2.6 1.4 2.3 4.6 0.5 0.1 0.0 5.1 0.2 16.9 68.0 0.2 24.0 0.4 0.1 0.0 0.1 103.7 0.2 0.1 0.2 0.1 3.2 61.0 0.3 0.0 15.4 11.2 0.3 1.2 0.1 0.0 80.0 0.2 0.2 11.0 0.0 0.7 0.1 7.6 0.8 0.0 312.3 0.4 0.1 97.0 0.5 0.0 23.9 0.0 0.3 0.0 0.8 23.3 328.5 0.1 1.4 0.0 0.1 1.2 6.6 0.5 0.0 0.1 0.0 2.5 0.2 3.8 0.3 1.3 3.2 0.1 0.6 1.1 1.5 0.0 4.7 0.4 0.0 2.0 0.5 13.0 13.5 13.1 15.6 13.7 18.9 22.3 16.0 14.4 14.3 14.5 13.6 33.2 9.6 4.8 20.5 1.1 22.0 0.2 39.6 1.2 1.7 0.2 1.0 9.1 0.0 24.8 0.0 0.0 0.1 0.7 1.0 0.0 0.2 0.9 13.5 24.2 59.8 0.0 0.0 0.7 10.4 0.8 171.2 1.1 24.8 6.3 6.3 33.5 2.5 0.8 0.0 2.3 0.1 6.1 4.1 10.1 0.4 1.5 6.9 1.8 12.2 0.8 0.1 1.0 1.0 0.1 1.3 5.3 1.2 0.5 0.5 3.3 0.9 5.8 0.1 0.0 35.7 37.1 0.2 0.3 1.1 15.9 0.3 1.5 1.1 0.2 2.6 ACKR4 "CCBP2, CCR11, CCRL1, CCX-CKR, PPR1, VSHK1" ENSG00000129048 "Atypical chemokine receptor 4" Q9NPB9 3 132597270-132618967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Fibroblasts: 21.4;Proximal enterocytes: 19.1;Respiratory ciliated cells: 15.7" "Cancer enhanced" "Detected in many" "stomach cancer: 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "BJ hTERT+: 285.1" "Group enriched" "Detected in some" 7 "cerebellum: 4.7;pons and medulla: 1.5" "Low region specificity" "Detected in all" HPA054926 Approved Vesicles,Mitochondria NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Mitochondria" "HPA054926: " "unprognostic (1.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.62e-2)" "unprognostic (8.27e-2)" "unprognostic (5.17e-2)" "unprognostic (4.55e-3)" "unprognostic (8.93e-2)" "unprognostic (2.26e-1)" "unprognostic (4.85e-2)" "unprognostic (4.20e-3)" "unprognostic (1.03e-3)" "unprognostic (2.69e-3)" "unprognostic (1.95e-1)" "unprognostic (2.01e-1)" "unprognostic (1.86e-1)" "unprognostic (1.18e-1)" "unprognostic (1.22e-1)" 11.1 1.4 0.6 1.0 0.2 0.8 5.5 0.3 0.3 0.7 0.9 1.9 15.8 3.7 1.7 1.4 2.0 6.5 5.7 0.4 0.0 1.1 1.0 8.0 2.1 0.3 0.5 1.0 2.6 0.0 6.7 0.2 0.3 0.5 1.3 0.6 7.1 1.9 0.5 8.9 13.0 2.2 0.3 1.6 10.2 0.4 0.1 0.5 1.4 1.0 1.6 4.6 1.1 0.2 0.2 0.0 0.2 0.2 19.9 10.7 0.1 47.7 285.1 2.8 7.9 0.2 0.4 3.3 0.0 29.9 0.2 0.1 0.0 0.0 1.8 1.1 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.2 0.0 1.3 0.0 0.0 4.9 0.1 0.2 0.6 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 1.0 0.1 0.1 0.2 0.0 0.5 0.1 0.7 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.3 0.3 0.4 0.0 0.3 0.5 0.3 0.3 0.1 0.2 1.6 38.5 1.1 0.7 0.1 6.5 0.6 1.3 0.0 1.6 0.3 0.3 0.7 1.5 2.3 5.5 6.2 0.2 0.1 1.1 0.0 0.2 2.9 2.9 0.6 3.9 0.0 0.0 0.6 12.1 0.1 21.4 10.7 0.6 0.0 0.7 9.7 0.2 0.4 1.7 0.5 0.8 0.0 0.3 5.1 0.4 2.1 0.3 1.8 1.9 6.8 0.9 0.0 0.0 0.3 5.1 0.1 2.6 0.5 0.4 19.1 3.0 15.7 3.4 0.0 1.3 2.6 0.1 0.1 0.6 6.5 0.3 0.5 12.5 3.7 1.2 ACOT8 "hACTE-III, hTE, NAP1, PTE-2, PTE1" ENSG00000101473 "Acyl-CoA thioesterase 8" O14734 20 45841721-45857405 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Host-virus interaction, Lipid metabolism, Peroxisome biogenesis" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 104.2;Late spermatids: 90.3;Proximal enterocytes: 105.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010261 Approved Supported Vesicles,Mitochondria NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles Mitochondria "CAB010261: AB_2221664" "unprognostic (2.36e-2)" "unprognostic (6.95e-2)" "unprognostic (2.12e-1)" "unprognostic (1.28e-2)" "unprognostic (2.13e-1)" "unprognostic (4.27e-1)" "unprognostic (1.03e-3)" "unprognostic (2.92e-2)" "unprognostic (4.70e-1)" "unprognostic (1.72e-1)" "unprognostic (2.28e-2)" "unprognostic (2.03e-2)" "prognostic favorable (3.18e-4)" "unprognostic (2.79e-1)" "unprognostic (1.23e-1)" "unprognostic (4.61e-2)" "unprognostic (2.98e-1)" 8.3 31.7 27.8 8.6 29.8 18.1 7.6 28.2 35.2 9.3 24.3 18.5 21.1 8.5 11.0 17.5 10.7 9.2 28.1 29.8 28.6 21.3 26.0 11.0 12.6 27.0 28.5 8.0 15.6 15.1 15.4 7.1 28.7 12.7 12.8 9.2 12.8 5.9 28.7 17.0 20.5 6.4 26.0 12.3 21.3 20.2 28.7 13.1 11.4 17.8 9.7 11.0 10.4 28.1 16.8 20.2 6.8 13.4 18.3 11.0 11.7 11.1 9.5 15.1 13.7 29.2 22.7 20.8 48.2 16.3 35.4 32.3 13.0 27.8 6.6 15.5 22.3 21.2 25.1 28.5 16.9 19.9 19.3 12.9 21.3 15.1 10.9 22.6 9.4 23.6 18.8 24.2 11.0 47.4 28.7 27.0 11.8 32.4 52.2 14.0 12.2 37.6 16.5 19.1 23.1 10.8 24.9 61.7 39.5 10.6 34.4 48.8 11.6 37.9 8.5 19.5 18.9 20.7 33.8 14.0 46.3 21.2 20.8 34.3 34.3 43.6 24.8 34.6 21.8 27.5 23.2 21.9 36.7 27.9 20.0 21.6 25.0 16.3 34.2 23.3 31.9 26.7 27.8 29.8 28.2 35.2 29.8 28.6 27.0 28.5 28.7 26.0 28.7 28.1 8.2 35.3 14.1 5.9 17.9 6.1 12.3 21.9 8.6 19.2 9.8 10.9 9.3 11.5 17.7 12.9 16.7 34.2 11.8 104.2 64.6 21.6 38.5 14.2 10.4 10.9 19.2 17.0 12.3 21.0 20.9 11.4 19.9 14.0 14.0 27.6 11.4 25.5 27.8 8.4 12.0 37.3 10.2 18.6 7.1 90.3 9.9 17.5 10.6 3.7 27.5 17.8 34.0 5.0 9.6 21.6 68.4 8.6 21.3 11.3 105.4 81.5 27.1 22.8 13.1 5.8 12.8 27.0 10.2 16.1 8.0 19.4 13.9 37.6 30.3 16.0 ACOX2 "BRCACOX, BRCOX, THCCox" ENSG00000168306 "Acyl-CoA oxidase 2" Q99424 3 58505136-58537283 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 177.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 89.0;Proximal enterocytes: 27.9;Proximal tubular cells: 51.0" "Cancer enhanced" "Detected in many" "liver cancer: 25.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 16.4;ASC TERT1: 25.9;fHDF/TERT166: 9.2;Hep G2: 10.8;HSkMC: 17.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA038280, HPA064845" Enhanced Approved Vesicles,Cytosol No No 29000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Vesicles Cytosol "HPA038280: AB_10672623, HPA064845: AB_2685368" "unprognostic (6.62e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-1)" "unprognostic (2.51e-2)" "unprognostic (8.34e-2)" "unprognostic (1.48e-2)" "unprognostic (8.67e-3)" "unprognostic (6.45e-2)" "unprognostic (1.00e-1)" "unprognostic (1.85e-1)" "unprognostic (1.70e-3)" "unprognostic (1.26e-2)" "unprognostic (1.68e-3)" "unprognostic (4.00e-3)" "unprognostic (2.34e-1)" "unprognostic (1.26e-1)" "unprognostic (5.63e-3)" 8.8 8.3 4.1 2.1 4.6 0.1 5.8 4.4 4.5 9.3 16.8 12.9 25.4 9.4 5.8 6.3 10.8 8.2 16.7 4.3 4.5 42.1 177.3 6.2 1.7 5.3 4.8 11.2 4.6 9.6 4.6 3.4 4.4 10.8 8.3 1.8 7.2 9.8 8.2 2.9 21.6 11.2 4.5 1.4 4.0 4.9 4.9 4.0 16.1 17.0 1.2 8.7 6.0 4.1 0.0 0.0 0.2 0.0 16.4 25.9 4.7 3.1 0.2 0.0 0.4 0.8 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 2.3 0.0 0.0 17.4 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 4.6 4.4 4.5 4.3 4.5 5.3 4.8 4.4 4.5 4.9 4.1 1.9 3.2 5.8 11.1 0.6 0.6 7.6 0.5 5.7 0.3 1.3 3.8 14.3 4.3 0.9 3.7 0.0 0.7 0.0 4.2 15.6 0.3 0.1 0.4 1.3 1.6 3.0 2.7 0.6 1.9 0.4 8.6 2.0 0.2 1.3 8.6 6.1 89.0 5.2 1.7 0.6 5.1 0.0 1.9 0.4 1.8 10.8 1.7 0.0 1.0 0.5 10.8 0.0 0.5 0.0 0.4 0.8 8.6 0.1 0.6 27.9 51.0 0.0 0.8 6.6 7.0 5.2 0.4 0.4 3.0 0.3 0.8 0.3 9.6 4.6 3.8 ACRBP "CT23, OY-TES-1, SP32" ENSG00000111644 "Acrosin binding protein" Q8NEB7 12 6638075-6647433 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "testis: 283.5" "Cell type enhanced" "Detected in many" "Early spermatids: 1097.8;Late spermatids: 723.5;Macrophages: 220.0;Spermatocytes: 387.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "classical monocyte: 12.5;intermediate monocyte: 15.8;myeloid DC: 17.7;non-classical monocyte: 31.0" "Group enriched" "Detected in many" 9 "dendritic cells: 17.7;monocytes: 31.0" "Cell line enhanced" "Detected in some" "HEL: 5.3;HMC-1: 6.7;U-266/70: 15.0;U-266/84: 10.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039081, HPA039082" Enhanced Approved Nucleoplasm,Vesicles "Secreted in male reproductive system" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Vesicles" "HPA039081: AB_10670920, HPA039082: AB_10671036" "unprognostic (7.76e-3)" "unprognostic (2.27e-1)" "unprognostic (3.41e-3)" "unprognostic (2.31e-2)" "unprognostic (3.65e-2)" "unprognostic (2.13e-2)" "unprognostic (2.42e-1)" "unprognostic (3.40e-3)" "unprognostic (2.85e-1)" "unprognostic (5.47e-3)" "unprognostic (1.17e-2)" "unprognostic (1.43e-1)" "unprognostic (9.41e-3)" "unprognostic (1.25e-1)" "unprognostic (2.56e-1)" "unprognostic (1.44e-1)" "unprognostic (2.80e-4)" 2.2 0.9 0.9 3.8 1.3 10.7 1.1 1.9 1.4 1.9 1.1 2.9 8.4 1.4 14.2 0.9 2.1 4.1 0.6 0.9 1.0 1.8 2.2 2.8 5.5 1.3 1.2 0.7 2.9 0.3 0.9 2.3 1.3 2.0 2.1 1.8 1.3 1.1 0.4 1.7 8.1 2.1 1.1 9.2 1.9 283.5 1.2 3.0 13.8 0.4 3.6 2.4 0.9 1.5 0.2 0.1 0.8 2.5 0.8 1.2 1.3 0.0 0.0 0.1 0.1 0.0 1.8 0.3 0.8 0.2 0.1 0.0 0.4 0.0 0.2 0.8 0.0 5.3 0.6 0.0 1.8 0.1 6.7 0.1 3.3 0.9 0.1 0.6 0.6 1.7 3.5 0.0 0.1 0.3 0.2 1.9 1.5 4.3 0.0 0.3 0.1 0.3 0.5 0.1 1.0 0.3 0.0 0.7 1.1 1.2 0.0 1.9 0.7 0.1 0.8 0.5 0.0 15.0 10.5 0.5 0.5 2.0 0.0 1.5 12.5 1.2 0.2 15.8 0.0 1.3 0.0 0.0 17.7 1.9 0.2 0.1 2.6 0.7 31.0 4.5 0.0 10.6 0.9 1.3 1.9 1.4 0.9 1.0 1.3 1.2 1.3 1.1 1.2 1.5 0.3 0.0 1.3 0.7 1.5 0.1 0.1 0.0 1.2 1.7 0.5 0.5 1.0 0.0 0.1 0.0 0.0 0.1 1.9 0.9 0.0 0.2 1097.8 0.7 0.5 1.5 0.0 5.7 0.2 0.5 0.3 0.5 0.0 0.8 6.3 0.4 1.8 0.3 9.8 0.0 0.3 0.8 0.0 20.5 3.4 723.5 8.1 220.0 0.0 1.0 7.6 1.1 10.3 0.0 0.4 0.1 1.6 4.5 0.5 0.0 7.6 1.1 0.2 1.3 6.6 0.3 0.2 387.5 7.5 0.3 0.0 0.1 1.0 0.4 1.1 0.1 ACSBG1 "BG1, BGM, FLJ30320, hBG1, hsBG, KIAA0631, MGC14352" ENSG00000103740 "Acyl-CoA synthetase bubblegum family member 1" Q96GR2 15 78167468-78245688 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 56.6;skin 1: 14.3" "Cell type enriched" "Detected in some" 5 "Astrocytes: 158.0" "Cancer enriched" "Detected in some" 4 "glioma: 3.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "NTERA-2: 3.1;SK-MEL-30: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041642, CAB045955, HPA058869" Approved Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 5: NTERA-2 - Transcription" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "CAB045955: AB_11124196, HPA041642: AB_2677593, HPA058869: AB_2683840" "unprognostic (1.28e-1)" "unprognostic (1.63e-2)" "unprognostic (1.29e-2)" "unprognostic (2.28e-1)" "unprognostic (2.29e-2)" "unprognostic (4.18e-2)" "unprognostic (1.32e-2)" "unprognostic (1.58e-2)" "unprognostic (1.86e-1)" "unprognostic (5.64e-2)" "unprognostic (2.02e-1)" "unprognostic (4.13e-1)" "unprognostic (1.05e-1)" "unprognostic (1.40e-1)" "unprognostic (2.96e-1)" "unprognostic (4.19e-2)" "unprognostic (1.42e-2)" 0.1 5.5 23.0 0.4 42.6 2.4 1.6 30.5 24.0 0.5 0.0 1.1 0.4 0.2 0.7 0.3 2.8 0.2 0.8 19.6 35.9 0.5 0.4 0.5 0.4 46.0 39.9 0.3 0.2 0.0 0.5 0.1 47.7 0.8 0.1 0.6 0.3 0.2 0.2 14.3 0.5 0.2 45.8 0.3 0.3 3.7 36.6 3.4 0.2 0.0 0.1 0.3 0.5 56.6 0.3 0.0 0.6 0.9 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.2 0.2 0.3 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.1 0.5 0.3 0.6 0.3 0.0 0.2 0.6 0.2 0.0 0.1 0.1 0.2 0.0 0.4 0.2 0.4 0.0 0.1 0.2 0.5 3.1 0.2 0.1 0.1 0.4 0.2 0.0 0.4 0.2 0.3 0.1 0.4 1.5 0.3 0.1 0.2 0.4 0.2 0.2 0.1 0.1 0.3 0.1 0.3 0.1 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 1.0 0.0 0.3 23.0 42.6 30.5 24.0 19.6 35.9 46.0 39.9 47.7 45.8 36.6 56.6 0.1 0.0 2.0 158.0 0.6 1.1 0.6 0.3 0.6 1.9 0.2 0.1 3.0 0.0 2.7 0.0 4.2 0.2 0.5 0.3 0.0 0.0 1.8 4.4 0.3 0.2 0.0 4.6 0.7 0.0 0.2 0.7 0.5 0.3 0.0 0.1 0.0 0.0 0.1 0.0 1.0 0.2 0.0 0.0 0.0 1.7 0.3 4.0 1.8 2.8 0.1 0.2 1.0 7.5 26.9 0.2 0.0 0.0 0.9 0.3 0.1 0.2 19.1 3.3 0.0 0.3 1.0 2.0 10.0 0.4 0.6 0.4 0.5 1.6 0.1 0.7 ACSL1 "ACS1, FACL1, FACL2, LACS, LACS1, LACS2" ENSG00000151726 "Acyl-CoA synthetase long chain family member 1" P33121 4 184755595-184826818 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 770.4;liver: 1319.0;skeletal muscle: 731.8" "Cell type enhanced" "Detected in many" "Early spermatids: 355.8;Hepatocytes: 1170.0;Late spermatids: 456.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "neutrophil: 475.2" "Lineage enriched" "Detected in all" 9 "granulocytes: 475.2" "Cell line enhanced" "Detected in all" "ASC diff: 1124.0;ASC TERT1: 275.2;HSkMC: 609.5;RPTEC TERT1: 358.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011316, HPA011317, HPA011964" Enhanced Uncertain Vesicles NA NA 44000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA011316: AB_1844536, HPA011317: , HPA011964: AB_1844537" "unprognostic (1.10e-2)" "unprognostic (3.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.64e-3)" "unprognostic (2.93e-2)" "unprognostic (1.21e-2)" "unprognostic (1.82e-3)" "unprognostic (2.75e-2)" "unprognostic (1.79e-1)" "unprognostic (5.89e-2)" "unprognostic (9.83e-2)" "unprognostic (3.15e-1)" "prognostic favorable (1.25e-5)" "unprognostic (2.77e-1)" "unprognostic (4.38e-2)" "unprognostic (6.25e-3)" "unprognostic (3.13e-2)" 770.4 43.3 32.5 94.8 43.9 337.9 316.7 45.2 70.2 62.1 60.7 34.0 32.4 41.6 78.2 66.0 50.6 36.2 172.7 34.4 39.1 218.7 1319.0 173.7 20.7 63.2 44.4 15.5 49.3 57.0 39.6 30.0 56.2 91.3 16.3 28.4 84.2 30.1 731.8 173.0 34.5 42.8 45.2 132.8 54.2 41.9 63.2 12.2 51.3 442.0 24.7 73.2 57.7 70.8 51.6 15.9 9.7 24.6 1124.0 275.2 8.3 29.1 13.8 16.1 11.2 3.9 14.0 22.2 3.0 32.8 38.4 29.7 43.1 17.8 13.3 107.1 17.7 16.6 13.1 40.5 183.4 41.9 37.2 609.5 140.7 13.6 67.1 27.6 21.1 3.6 7.5 59.4 77.0 26.9 3.1 55.1 2.0 32.5 23.3 8.0 8.6 27.0 358.4 135.9 36.3 35.1 25.4 70.8 86.5 3.9 26.9 39.8 25.1 13.8 16.8 34.5 8.7 24.5 13.5 8.9 45.6 56.3 22.4 16.5 54.7 17.7 3.3 30.9 2.8 3.3 2.3 1.5 13.1 3.4 2.5 2.2 475.2 4.4 23.0 2.4 4.9 20.8 32.5 43.9 45.2 70.2 34.4 39.1 63.2 44.4 56.2 45.2 63.2 70.8 7.5 25.6 121.0 6.5 15.7 21.0 16.0 14.0 5.2 6.6 49.7 10.3 119.1 25.8 33.5 31.3 18.8 10.2 7.1 4.3 93.9 4.6 355.8 9.8 25.0 9.8 0.0 34.1 15.2 12.8 2.2 19.4 36.2 24.6 24.1 1.5 18.2 1170.0 41.8 3.3 22.8 4.7 85.5 140.7 14.6 456.6 19.3 170.1 32.0 6.5 40.5 3.1 1.0 8.5 89.8 8.6 1.6 16.6 8.6 51.3 1.5 111.1 26.8 11.4 13.1 11.1 12.4 10.5 16.7 26.4 41.1 3.4 10.6 1.8 3.2 23.1 ACSM5 FLJ20581 ENSG00000183549 "Acyl-CoA synthetase medium chain family member 5" Q6NUN0 16 20409534-20441336 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "liver: 276.6" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 237.8" "Group enriched" "Detected in some" 7 "liver cancer: 20.5;renal cancer: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 5.3;ASC TERT1: 11.5;HSkMC: 13.8;U-87 MG: 8.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA041435 Uncertain Uncertain Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA041435: AB_10961121" "unprognostic (1.01e-1)" "unprognostic (1.61e-3)" "unprognostic (3.73e-2)" "unprognostic (1.98e-2)" "unprognostic (1.03e-1)" "unprognostic (1.59e-2)" "unprognostic (1.84e-2)" "unprognostic (4.64e-3)" "unprognostic (1.64e-1)" "unprognostic (2.01e-2)" "unprognostic (2.15e-2)" "unprognostic (2.33e-1)" "unprognostic (5.11e-3)" "unprognostic (2.09e-2)" "unprognostic (3.85e-2)" "unprognostic (2.78e-2)" "unprognostic (1.57e-1)" 25.5 2.5 7.1 0.6 5.2 0.6 10.7 4.7 5.0 2.8 3.0 3.7 0.8 1.2 7.1 1.0 1.7 2.3 3.3 5.5 7.9 25.4 276.6 2.1 1.9 6.3 6.8 0.8 0.6 1.0 0.5 1.4 6.8 0.6 1.2 0.5 0.9 0.9 13.9 2.3 1.9 1.0 6.7 4.6 3.4 0.9 8.2 0.7 4.2 1.7 0.7 1.1 2.2 8.2 0.0 0.0 0.1 0.1 5.3 11.5 0.0 0.1 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.2 0.0 13.8 0.0 0.8 0.1 0.2 0.0 0.0 0.1 0.5 1.6 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 2.2 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 8.5 0.1 0.0 0.1 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 7.1 5.2 4.7 5.0 5.5 7.9 6.3 6.8 6.8 6.7 8.2 8.2 0.4 0.0 0.0 1.0 0.5 0.0 0.1 0.0 0.0 0.0 0.8 0.4 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.5 0.5 0.0 0.3 1.2 0.0 13.5 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.3 6.1 237.8 3.7 0.0 0.2 0.0 0.0 11.7 1.5 0.8 9.3 3.5 0.0 7.5 1.3 0.9 0.0 1.5 0.1 0.0 0.0 6.0 0.0 0.2 0.0 52.1 0.0 0.1 0.0 11.3 0.3 0.2 0.3 0.1 0.6 0.0 0.7 0.9 0.1 0.2 ACTR10 "ACTR11, Arp10, Arp11, HARP11" ENSG00000131966 "Actin related protein 10" Q9NZ32 14 58200080-58235636 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000699 Approved "Vesicles,Plasma membrane,Focal adhesion sites" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane, Focal adhesion sites" "HPA000699: " "prognostic unfavorable (3.24e-4)" "unprognostic (4.61e-2)" "unprognostic (6.22e-3)" "unprognostic (2.03e-2)" "unprognostic (4.42e-1)" "unprognostic (1.36e-2)" "prognostic unfavorable (2.71e-5)" "unprognostic (3.20e-1)" "unprognostic (9.30e-2)" "unprognostic (1.53e-1)" "unprognostic (4.86e-1)" "unprognostic (2.36e-1)" "prognostic favorable (8.48e-8)" "unprognostic (1.01e-2)" "unprognostic (2.39e-1)" "unprognostic (2.43e-2)" "unprognostic (8.48e-2)" 12.6 18.0 22.4 3.1 22.4 5.4 12.5 23.4 41.5 15.9 24.5 13.5 2.7 10.2 5.0 16.4 12.7 4.2 22.9 22.2 22.9 18.0 18.5 10.8 4.2 22.3 22.4 15.8 17.4 8.7 20.3 6.4 22.5 14.5 4.4 5.5 10.3 4.7 10.2 13.2 11.3 6.1 22.1 14.7 13.2 10.8 23.0 5.3 13.6 4.1 4.3 12.0 13.9 22.9 4.1 2.6 4.6 1.8 15.3 7.3 2.3 3.1 3.6 4.9 6.1 3.5 4.8 6.3 4.5 6.7 3.0 4.2 6.2 4.5 7.2 3.3 15.3 2.4 4.6 6.9 13.0 4.3 3.4 9.7 6.8 4.5 8.5 4.3 6.7 3.6 2.1 5.0 10.3 11.3 5.7 16.2 2.3 4.0 20.8 4.0 8.0 3.7 9.1 5.2 2.6 2.9 5.9 4.9 16.9 5.2 8.4 7.1 5.4 5.3 11.3 4.9 2.8 2.9 2.0 7.1 5.8 3.3 3.2 15.7 5.4 8.6 6.2 7.3 9.2 6.1 7.0 6.2 4.3 4.1 7.2 7.5 7.8 5.9 8.5 4.8 5.5 4.0 22.4 22.4 23.4 41.5 22.2 22.9 22.3 22.4 22.5 22.1 23.0 22.9 68.3 60.9 44.2 28.7 39.9 53.3 66.4 125.7 34.1 71.4 35.8 43.3 77.0 42.9 75.1 51.5 29.2 110.1 46.4 59.6 125.2 81.2 8.7 40.3 46.7 54.4 33.6 60.0 48.6 59.6 76.9 73.4 32.1 29.7 43.7 49.6 47.8 31.8 77.8 57.2 47.3 48.1 105.8 32.0 38.4 11.6 88.3 47.2 74.7 23.4 52.8 101.4 35.0 40.2 54.6 75.0 29.1 80.1 34.7 59.1 56.3 111.7 67.7 72.0 78.9 54.5 96.6 116.4 60.4 45.7 64.4 156.0 46.1 81.3 41.3 54.6 ADAL ENSG00000168803 "Adenosine deaminase like" Q6DHV7 15 43330672-43354569 "Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 81.3;Rod photoreceptor cells: 84.8;Spermatocytes: 99.5;Spermatogonia: 82.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039879, HPA048175, HPA058795" Approved Approved "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Nuclear speckles, Vesicles" "HPA039879: , HPA048175: AB_2680298, HPA058795: " "unprognostic (1.65e-2)" "unprognostic (1.53e-3)" "unprognostic (9.80e-2)" "unprognostic (3.15e-3)" "unprognostic (2.46e-3)" "unprognostic (1.86e-1)" "unprognostic (2.00e-1)" "unprognostic (5.83e-2)" "unprognostic (5.90e-2)" "unprognostic (2.68e-1)" "unprognostic (6.85e-3)" "unprognostic (1.69e-1)" "prognostic favorable (7.64e-9)" "unprognostic (2.37e-3)" "unprognostic (8.77e-2)" "unprognostic (5.31e-2)" "unprognostic (2.44e-2)" 6.2 6.6 6.7 4.2 7.1 4.4 5.9 7.6 9.6 3.6 10.2 5.7 5.8 4.3 8.4 4.1 3.3 3.8 20.9 6.3 7.4 11.9 8.2 3.5 4.8 6.7 7.2 3.6 3.6 10.4 6.1 2.7 7.0 6.2 4.8 21.2 4.2 6.4 20.4 2.6 4.6 4.7 6.9 3.8 4.0 11.1 7.1 5.4 10.9 23.4 4.8 4.6 3.0 7.4 6.8 3.4 13.3 15.1 5.5 7.1 6.3 8.1 8.2 12.6 19.3 14.2 3.5 8.0 13.0 8.9 16.7 7.5 0.0 5.7 10.8 8.5 8.0 19.0 23.1 12.0 6.9 0.0 14.8 9.1 10.3 8.5 8.7 8.1 2.7 19.4 21.1 16.2 13.2 4.6 12.3 9.7 5.5 7.8 4.6 15.9 19.9 12.7 11.0 4.1 16.3 11.6 13.1 11.7 12.4 7.2 12.5 12.5 3.7 21.9 10.6 16.6 16.5 16.6 29.9 3.4 12.2 21.2 18.1 5.9 1.4 3.8 2.4 2.0 1.8 2.0 2.2 1.9 2.0 1.6 2.3 2.9 1.1 2.3 1.9 2.9 4.5 1.3 6.7 7.1 7.6 9.6 6.3 7.4 6.7 7.2 7.0 6.9 7.1 7.4 5.9 9.6 10.3 32.7 10.0 7.0 7.4 9.3 7.4 40.7 9.2 9.9 51.2 10.0 6.9 18.4 81.3 7.1 13.3 7.0 58.7 8.9 17.6 10.6 10.3 8.2 7.7 19.1 24.4 8.5 7.0 10.4 5.1 6.8 7.6 15.7 11.0 30.8 8.9 42.1 26.7 7.2 10.2 8.8 7.0 12.7 9.6 8.9 8.8 10.3 5.4 35.5 24.7 19.1 18.3 5.7 1.3 8.6 6.9 7.1 13.0 29.0 10.9 84.8 6.6 11.6 7.3 99.5 82.5 8.8 4.4 2.6 7.0 12.6 11.6 4.4 ADAM10 "CD156C, HsT18717, kuz, MADM" ENSG00000137845 "ADAM metallopeptidase domain 10" O14672 15 58588809-58749791 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Metalloprotease, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 377.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 296.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001709, HPA050670" Approved Supported "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 690000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" "CAB001709: , HPA050670: " "unprognostic (1.43e-1)" "unprognostic (1.38e-1)" "unprognostic (2.77e-1)" "unprognostic (5.04e-2)" "unprognostic (3.09e-1)" "unprognostic (2.70e-3)" "unprognostic (7.48e-2)" "prognostic unfavorable (8.46e-5)" "unprognostic (3.99e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (6.69e-2)" "unprognostic (2.57e-2)" "unprognostic (2.57e-3)" "unprognostic (9.14e-2)" "unprognostic (2.09e-2)" "unprognostic (1.60e-2)" 14.9 8.7 11.4 19.0 18.6 18.7 15.2 20.2 15.0 16.0 9.7 22.2 15.9 16.3 7.7 15.4 13.9 18.9 12.1 12.2 12.7 18.0 16.1 21.0 22.2 18.2 17.6 14.1 8.8 7.9 8.2 29.0 17.5 25.2 17.2 10.8 9.3 12.2 6.1 16.9 17.5 13.3 13.7 29.0 20.3 8.5 15.5 42.7 28.6 7.1 16.4 28.0 10.4 25.2 48.4 88.5 27.6 31.2 34.8 49.8 70.0 39.0 116.0 28.6 39.1 39.9 62.6 22.7 118.0 35.2 49.2 95.9 16.8 43.5 37.0 30.1 19.3 38.7 35.1 42.1 40.8 25.0 103.8 44.4 30.0 19.9 29.2 41.1 55.6 45.0 24.5 57.9 50.4 15.4 89.5 32.0 40.2 15.4 14.6 36.4 91.6 57.1 66.6 121.4 29.9 20.3 44.0 52.8 73.1 60.0 30.4 55.0 41.4 37.1 41.2 296.6 39.6 30.7 70.7 23.5 54.1 50.8 67.3 30.9 36.2 19.2 12.8 41.1 19.2 8.3 12.7 11.6 23.6 9.6 12.7 10.8 51.5 17.7 48.6 10.2 18.2 25.8 11.4 18.6 20.2 15.0 12.2 12.7 18.2 17.6 17.5 13.7 15.5 25.2 60.1 83.3 50.8 83.2 37.9 26.6 30.7 33.3 33.0 22.7 61.6 30.9 40.0 30.0 46.7 80.9 27.1 35.6 69.4 79.0 1.9 56.0 21.2 39.5 56.4 72.5 36.1 20.8 106.1 31.8 57.8 36.1 53.0 74.0 30.3 31.5 71.4 36.2 63.8 45.4 96.2 43.6 36.7 90.1 28.9 19.4 18.0 77.9 46.2 147.1 69.0 30.6 44.3 75.9 377.6 48.9 48.1 17.0 51.0 89.1 45.1 23.7 41.2 33.4 13.1 34.4 42.8 20.3 17.8 39.5 22.3 26.5 51.3 34.1 39.5 83.9 ADAM15 MDC15 ENSG00000143537 "ADAM metallopeptidase domain 15" Q13444 1 155050566-155062775 "Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 164.5;Extravillous trophoblasts: 172.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 39.1;intermediate monocyte: 26.5;myeloid DC: 64.0" "Group enriched" "Detected in all" 5 "dendritic cells: 64.0;monocytes: 39.1" "Cell line enhanced" "Detected in many" "PC-3: 329.5;RPMI-8226: 361.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011633, HPA072878" Uncertain Uncertain Vesicles NA NA 640000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA011633: AB_1844574, HPA072878: " "unprognostic (6.35e-3)" "unprognostic (1.51e-1)" "unprognostic (1.60e-1)" "unprognostic (7.60e-2)" "prognostic unfavorable (5.83e-5)" "unprognostic (2.09e-1)" "prognostic unfavorable (3.49e-4)" "unprognostic (2.07e-2)" "unprognostic (1.09e-1)" "unprognostic (1.16e-1)" "unprognostic (1.06e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (5.64e-9)" "unprognostic (3.35e-2)" "unprognostic (6.20e-2)" "unprognostic (2.04e-2)" "unprognostic (7.40e-2)" 70.1 18.5 12.5 21.4 16.0 34.1 64.7 16.9 13.9 40.3 7.1 38.3 16.4 42.5 7.6 79.1 41.5 21.6 63.1 10.5 13.8 32.4 15.1 50.0 10.0 20.2 15.1 25.5 25.5 30.0 14.1 39.1 16.8 40.0 23.8 3.4 45.3 16.7 22.7 107.9 31.3 38.6 17.3 28.8 44.2 4.9 17.1 7.3 31.6 32.4 13.6 38.9 57.3 18.0 112.0 35.0 7.0 153.2 54.9 45.6 66.3 48.2 60.9 60.1 40.5 25.9 63.3 30.9 210.7 63.5 26.7 135.9 34.5 147.9 15.8 14.3 44.9 7.6 63.1 25.3 95.5 63.4 7.9 48.7 153.8 60.5 86.6 82.6 274.7 9.3 11.9 124.8 45.2 64.7 0.5 47.1 21.6 193.4 329.5 10.0 20.5 361.8 43.7 29.7 20.8 44.7 105.2 131.2 41.8 10.7 194.8 38.9 205.1 58.6 24.6 58.9 54.1 13.9 11.7 13.7 42.7 47.6 65.4 0.0 39.1 0.8 9.5 26.5 6.5 2.0 4.7 5.6 64.0 2.1 2.0 2.5 1.4 1.6 6.2 5.3 8.9 22.8 12.5 16.0 16.9 13.9 10.5 13.8 20.2 15.1 16.8 17.3 17.1 18.0 164.5 3.2 6.7 8.8 6.6 48.9 30.4 81.6 47.8 9.7 34.6 20.7 11.5 35.8 38.3 9.2 29.2 13.0 8.1 100.4 0.0 33.4 1.7 13.3 9.2 120.8 12.7 4.6 8.1 25.5 172.4 19.8 85.6 15.4 1.3 8.5 62.2 19.9 31.7 6.7 9.8 80.7 18.3 65.0 43.6 1.3 17.4 27.2 14.2 15.9 28.8 8.8 13.4 9.0 16.8 42.1 50.9 18.0 8.0 55.2 47.4 2.6 22.9 17.0 13.1 15.7 14.5 0.8 6.4 91.2 57.1 17.8 8.6 2.7 76.9 40.0 ADAM19 MLTNB ENSG00000135074 "ADAM metallopeptidase domain 19" Q9H013 5 157395534-157575775 "Plasma proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 56.7;Cone photoreceptor cells: 62.6;Extravillous trophoblasts: 81.8;Langerhans cells: 49.3;monocytes: 83.5;Plasma cells: 53.8;Rod photoreceptor cells: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 128.3;eosinophil: 139.9;memory B-cell: 50.8;naive B-cell: 53.5;neutrophil: 70.5;plasmacytoid DC: 66.8" "Group enriched" "Detected in many" 5 "B-cells: 53.5;dendritic cells: 66.8;granulocytes: 139.9" "Cell line enhanced" "Detected in many" "HDLM-2: 109.7;U-251 MG: 206.5" "Low region specificity" "Detected in all" HPA055537 Approved Vesicles NA NA 17000 "Cluster 2: Granulocytes - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" Vesicles "HPA055537: AB_2797253" "unprognostic (4.71e-1)" "unprognostic (1.01e-1)" "unprognostic (1.77e-1)" "unprognostic (4.64e-2)" "unprognostic (1.81e-3)" "unprognostic (2.63e-1)" "unprognostic (2.16e-2)" "unprognostic (1.82e-2)" "unprognostic (1.76e-2)" "unprognostic (2.80e-1)" "unprognostic (1.42e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.90e-12)" "unprognostic (1.44e-1)" "unprognostic (4.38e-2)" "unprognostic (2.22e-1)" "unprognostic (1.11e-2)" 4.9 3.6 2.6 24.0 3.3 7.7 2.7 5.3 4.6 4.9 0.4 22.8 5.8 8.0 2.6 5.1 7.4 8.9 24.7 3.1 3.8 2.1 9.6 13.2 29.0 5.1 4.5 3.5 0.9 0.1 1.8 13.1 4.7 7.6 6.7 22.6 1.9 6.3 6.5 1.4 18.7 16.3 3.1 22.6 9.6 1.6 4.5 7.4 4.2 2.8 30.2 18.8 5.2 3.9 38.8 6.0 11.5 0.1 0.8 0.7 73.7 45.0 16.0 27.5 20.5 19.9 30.7 19.9 2.4 23.4 5.7 32.4 1.8 2.9 24.9 109.7 1.1 0.1 3.3 2.7 6.5 0.1 0.0 5.2 0.1 21.5 4.3 32.7 31.5 0.0 5.7 2.8 59.4 0.0 0.0 0.1 12.3 0.0 19.3 0.6 65.9 16.8 2.9 0.6 5.2 3.5 0.0 15.9 2.3 45.3 0.2 0.6 48.7 29.6 31.7 6.8 206.5 11.8 0.4 69.6 6.7 0.1 13.5 128.3 13.1 139.9 1.5 1.2 3.5 50.8 14.4 3.3 4.2 53.5 0.4 0.4 70.5 0.4 0.1 66.8 16.6 9.2 2.6 3.3 5.3 4.6 3.1 3.8 5.1 4.5 4.7 3.1 4.5 3.9 1.5 6.4 0.6 2.0 56.7 2.2 0.1 1.2 0.0 37.7 0.5 0.4 5.6 0.0 0.7 3.7 62.6 1.1 22.0 0.1 0.0 0.5 4.1 0.5 6.8 5.6 0.0 1.7 24.2 1.5 81.8 6.5 0.5 0.2 0.0 0.3 4.2 7.5 1.7 15.2 21.2 0.1 0.0 9.0 49.3 1.3 5.6 12.4 1.8 10.3 83.5 2.4 1.0 13.0 28.7 2.2 0.1 7.9 53.8 0.2 0.0 0.1 0.1 43.9 6.6 12.3 13.3 0.0 1.1 2.5 1.4 8.3 24.0 1.7 0.3 0.2 ADAM32 ENSG00000197140 "ADAM metallopeptidase domain 32" Q8TC27 8 39106990-39284917 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 27.4" "Cell type enhanced" "Detected in many" "Early spermatids: 189.0;Excitatory neurons: 37.3;Late spermatids: 50.5;Spermatocytes: 99.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 1.0;MCF7: 1.1;U-2 OS: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA044156, HPA062151" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles Nucleoplasm "HPA044156: AB_10796798, HPA062151: AB_2684699" "unprognostic (2.13e-1)" "unprognostic (6.92e-2)" "unprognostic (4.63e-3)" "unprognostic (8.99e-2)" "unprognostic (1.48e-1)" "unprognostic (1.52e-2)" "unprognostic (5.66e-3)" "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" "unprognostic (1.12e-1)" "unprognostic (2.50e-1)" "unprognostic (3.38e-2)" "unprognostic (1.13e-7)" "unprognostic (3.42e-1)" "unprognostic (4.90e-2)" "unprognostic (8.34e-3)" "unprognostic (7.82e-2)" 1.0 1.0 1.0 0.2 0.9 0.4 1.0 3.2 1.5 0.6 0.0 0.5 0.0 0.4 0.6 0.2 0.5 0.4 0.7 0.9 1.3 0.2 0.0 0.3 0.1 0.1 0.5 0.6 1.8 0.0 0.4 0.1 0.4 0.6 0.4 0.9 0.5 0.3 0.2 0.7 0.2 0.1 0.1 0.7 0.3 27.4 1.0 0.0 0.3 0.1 0.1 0.5 0.4 1.3 0.2 0.4 0.0 0.2 0.6 0.0 0.0 0.4 0.1 0.4 0.2 0.1 0.9 0.0 0.1 0.7 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 1.0 0.1 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.2 0.5 1.1 0.1 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.7 1.3 0.0 0.5 0.0 0.1 0.0 0.2 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 1.0 0.9 3.2 1.5 0.9 1.3 0.1 0.5 0.4 0.1 1.0 1.3 1.0 0.0 0.0 11.8 0.0 0.9 1.1 0.7 0.6 8.2 2.5 2.3 1.7 1.5 0.4 1.8 18.8 0.3 0.1 0.4 0.0 0.4 189.0 5.7 3.6 1.0 4.2 0.0 37.3 1.3 0.2 2.4 0.0 9.8 0.0 3.3 0.7 0.4 0.5 0.0 29.8 1.1 0.0 0.0 1.0 50.5 2.8 0.6 0.0 9.4 0.1 1.0 0.0 18.6 17.6 2.8 0.1 3.0 0.1 1.7 0.0 0.2 1.4 3.8 0.0 3.4 0.9 99.9 2.9 0.5 0.0 0.1 0.2 3.7 1.4 1.5 ADAM9 "CORD9, KIAA0021, MCMP, MDC9, Mltng" ENSG00000168615 "ADAM metallopeptidase domain 9" Q13443 8 38996754-39105445 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Cone-rod dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 179.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 4.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004000 Approved "Endoplasmic reticulum,Vesicles" "Secreted - unknown location" NA NA 740000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "Endoplasmic reticulum" "HPA004000: AB_1844584" "prognostic unfavorable (1.14e-4)" "prognostic unfavorable (2.25e-4)" "unprognostic (1.32e-3)" "unprognostic (1.27e-1)" "unprognostic (2.86e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (7.21e-6)" "unprognostic (5.77e-2)" "unprognostic (1.55e-1)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.52e-5)" "unprognostic (5.83e-2)" "prognostic unfavorable (3.99e-4)" "unprognostic (2.80e-1)" "unprognostic (5.76e-2)" "unprognostic (2.27e-1)" "unprognostic (1.23e-2)" 34.2 28.0 7.1 28.8 8.2 2.1 21.5 8.5 8.3 34.8 11.4 32.9 24.5 29.7 15.2 29.7 19.3 47.1 32.1 6.0 8.4 34.9 13.5 51.4 9.7 10.2 7.5 16.8 12.7 52.5 7.8 47.4 9.0 34.9 41.7 18.5 54.9 34.8 24.1 16.1 23.0 51.6 9.4 24.0 44.2 11.1 10.6 5.9 39.9 25.0 13.2 56.1 24.3 11.5 188.3 163.6 63.5 32.6 117.2 374.0 67.0 259.6 382.4 191.7 177.9 82.7 147.1 10.1 86.1 247.2 156.7 79.5 30.8 249.7 373.2 6.9 21.5 12.1 102.8 73.0 226.4 8.9 19.1 287.5 139.2 193.3 212.7 341.0 268.9 15.2 21.5 53.2 406.2 25.0 7.2 4.4 8.3 175.2 46.7 3.8 106.3 27.6 299.3 62.4 6.4 11.5 78.4 90.9 57.8 72.9 67.3 12.0 374.2 109.9 97.9 213.9 124.1 12.9 29.5 7.7 175.8 12.0 72.1 0.3 4.0 0.5 0.1 1.3 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.1 0.5 0.8 0.6 0.3 0.1 0.9 7.1 8.2 8.5 8.3 6.0 8.4 10.2 7.5 9.0 9.4 10.6 11.5 14.4 48.1 37.0 16.0 3.8 35.9 66.6 78.3 26.7 19.3 23.4 9.8 49.7 24.3 82.1 35.0 20.9 24.1 8.9 44.4 3.9 90.2 14.4 42.1 35.3 20.5 10.7 2.5 47.5 115.4 85.1 42.0 80.5 82.1 5.1 26.4 25.0 7.5 125.9 5.0 38.0 32.2 44.7 60.2 44.8 7.8 28.6 54.7 21.4 33.7 21.8 17.5 1.0 30.7 26.7 179.4 30.6 24.8 5.2 108.7 24.9 41.1 51.9 25.1 13.1 31.3 31.9 4.3 2.5 20.2 21.5 34.3 5.6 11.2 32.7 103.8 ADAMTS13 "C9orf8, DKFZp434C2322, FLJ42993, MGC118899, MGC118900, TTP, vWF-CP, VWFCP" ENSG00000160323 "ADAM metallopeptidase with thrombospondin type 1 motif 13" Q76LX8 9 133414358-133459402 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 63.8" "Cell type enhanced" "Detected in many" "Astrocytes: 16.0;Early spermatids: 19.3;Excitatory neurons: 12.4;Inhibitory neurons: 12.4;Late spermatids: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042014, HPA042844, HPA052077" Approved Approved Vesicles "Secreted to blood" NA NA 1300000000 120000000 "Cluster 34: Basophils - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA042014: AB_2677798, HPA042844: AB_2678200, HPA052077: " "unprognostic (1.09e-1)" "unprognostic (1.45e-1)" "unprognostic (8.75e-4)" "unprognostic (1.49e-2)" "unprognostic (1.83e-1)" "unprognostic (3.02e-1)" "unprognostic (4.76e-2)" "unprognostic (2.54e-1)" "unprognostic (2.33e-2)" "unprognostic (1.88e-1)" "unprognostic (4.52e-5)" "unprognostic (1.11e-1)" "unprognostic (9.91e-2)" "unprognostic (4.78e-2)" "unprognostic (3.57e-1)" "unprognostic (1.82e-2)" "unprognostic (2.30e-3)" 2.5 2.8 6.9 0.5 7.3 0.6 2.8 7.6 10.0 5.0 5.3 4.3 3.2 4.2 2.9 2.4 5.7 1.2 6.0 7.1 6.2 9.6 63.8 2.8 0.9 7.0 6.7 6.7 6.2 1.5 12.5 0.8 7.1 6.4 0.9 1.1 2.5 1.4 4.3 2.6 4.4 0.6 6.3 2.6 9.8 13.5 7.2 0.8 6.1 1.4 0.5 4.4 3.1 7.1 0.0 0.8 1.9 2.6 1.5 1.3 0.8 0.7 0.5 0.2 0.3 0.3 2.1 0.2 0.9 0.4 0.6 0.3 0.1 0.4 0.1 1.2 1.7 0.2 0.9 0.4 1.1 0.0 0.7 3.6 0.9 0.2 0.7 1.2 0.1 1.3 0.0 0.8 0.3 3.3 0.0 0.9 2.0 1.1 1.1 0.2 0.2 0.9 0.8 0.8 1.3 4.0 1.4 0.6 1.2 3.9 3.7 0.4 0.5 1.5 0.8 0.9 0.0 1.7 0.3 0.3 1.1 0.2 1.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 7.3 7.6 10.0 7.1 6.2 7.0 6.7 7.1 6.3 7.2 7.1 0.9 0.0 2.0 16.0 1.2 0.3 0.3 0.9 0.0 1.7 1.4 1.9 4.2 4.3 2.4 0.0 0.0 0.2 0.2 1.0 1.9 0.6 19.3 3.6 1.6 0.9 1.2 0.0 12.4 0.4 0.3 1.5 4.6 3.3 0.0 3.0 5.0 1.6 0.2 3.3 12.4 1.3 0.0 0.6 0.0 13.6 0.9 0.3 0.0 7.5 0.0 1.7 0.0 2.0 5.5 0.3 3.0 1.5 0.4 0.4 1.5 0.9 0.7 1.8 0.0 0.4 0.7 6.0 3.9 0.3 0.4 0.1 0.5 1.7 0.9 0.3 ADAMTS19 ENSG00000145808 "ADAM metallopeptidase with thrombospondin type 1 motif 19" 5 129460281-129738683 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 10 "brain: 3.3;cervix: 10.2;endometrium 1: 9.8;placenta: 3.7;smooth muscle: 5.9" "Group enriched" "Detected in some" 4 "Excitatory neurons: 82.6;Inhibitory neurons: 79.7;Oligodendrocytes: 31.8" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.7;testis cancer: 1.2" "Region enhanced" "Detected in some" "basal ganglia: 3.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "MCF7: 15.9;SH-SY5Y: 34.8" "Region enriched" "Detected in single" 5 "olfactory bulb: 2.6" "Low region specificity" "Detected in many" "HPA056171, HPA058438" Uncertain Approved Vesicles,Midbody "Secreted to extracellular matrix" Yes NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Midbody" "HPA056171: AB_2683054, HPA058438: AB_2683718" "unprognostic (1.14e-1)" "unprognostic (1.42e-1)" "unprognostic (1.01e-1)" "unprognostic (1.10e-3)" "unprognostic (1.09e-1)" "unprognostic (6.49e-2)" "unprognostic (3.93e-2)" "unprognostic (4.17e-2)" "unprognostic (5.99e-3)" "unprognostic (5.17e-1)" "unprognostic (1.14e-1)" "unprognostic (5.88e-2)" "unprognostic (3.06e-2)" 0.0 0.6 1.0 0.0 3.3 0.0 0.0 0.0 1.5 10.2 0.1 0.2 0.1 9.8 0.0 0.2 0.2 0.0 0.2 0.8 0.2 0.3 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.1 0.0 3.7 0.0 0.1 0.3 0.5 0.3 0.0 0.5 0.0 0.1 5.9 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.3 0.1 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 15.9 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 34.8 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.3 0.0 1.5 0.8 0.2 0.0 0.5 0.0 0.0 0.3 0.6 0.1 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 1.4 0.0 0.0 1.8 0.0 15.6 0.0 0.3 0.0 0.0 1.5 0.5 8.9 0.2 0.0 0.0 82.6 0.2 0.7 1.0 0.0 0.7 0.0 0.0 0.0 0.0 1.7 0.0 79.7 0.1 0.0 0.0 0.3 0.7 0.0 0.1 0.0 1.0 0.0 1.1 0.0 12.5 31.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.4 0.1 0.1 0.0 5.2 0.1 0.1 0.3 0.0 ADAMTS2 "ADAM-TS2, ADAMTS-3, hPCPNI, NPI, PCINP" ENSG00000087116 "ADAM metallopeptidase with thrombospondin type 1 motif 2" O95450 5 179110853-179345461 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 32.2;Excitatory neurons: 17.9;Fibroblasts: 30.7;Hepatic stellate cells: 17.2;Kupffer cells: 71.4;Sertoli cells: 26.3;Smooth muscle cells: 20.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 36.0;ASC TERT1: 35.8;BJ: 31.4;fHDF/TERT166: 39.3;HHSteC: 115.5;HSkMC: 94.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028363, HPA028444" Uncertain Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA 2000000 "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Vesicles "HPA028363: , HPA028444: AB_10601964" "unprognostic (6.78e-2)" "unprognostic (7.83e-2)" "unprognostic (1.13e-1)" "unprognostic (5.50e-2)" "unprognostic (8.85e-3)" "unprognostic (4.80e-2)" "unprognostic (1.09e-1)" "unprognostic (2.22e-2)" "unprognostic (1.58e-1)" "unprognostic (1.91e-2)" "unprognostic (2.08e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.71e-8)" "unprognostic (1.32e-3)" "unprognostic (1.03e-2)" "unprognostic (7.16e-3)" "unprognostic (1.48e-2)" 36.9 10.9 0.8 2.4 4.2 0.3 22.7 0.9 3.5 20.6 0.9 10.5 1.4 21.7 0.5 5.5 15.5 6.1 22.3 0.5 0.9 7.5 15.8 29.6 1.8 4.5 3.3 12.1 5.8 0.4 15.1 9.7 4.2 9.0 1.4 0.2 5.3 1.8 2.9 9.4 11.6 9.1 0.2 38.4 9.3 3.9 2.5 0.4 6.8 0.8 0.6 15.0 16.7 2.2 0.0 0.0 0.1 0.7 36.0 35.8 0.0 31.4 5.4 11.5 12.4 0.1 0.0 0.0 0.2 39.3 0.7 0.1 1.8 0.0 5.1 0.0 1.5 0.0 0.1 2.3 115.5 0.0 0.0 94.4 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.1 0.8 0.8 0.0 0.1 0.0 0.0 0.3 0.0 0.0 5.9 1.2 0.1 0.0 0.4 1.9 0.0 10.7 0.0 19.1 3.0 24.5 0.0 0.3 0.0 0.0 0.9 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.8 4.2 0.9 3.5 0.5 0.9 4.5 3.3 4.2 0.2 2.5 2.2 3.3 0.0 1.1 1.6 0.1 2.2 0.4 0.0 2.2 0.3 0.2 5.2 1.5 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.3 0.9 32.2 1.4 0.0 0.0 17.9 0.0 0.3 30.7 0.0 0.8 1.3 6.5 17.2 0.5 5.1 0.0 8.5 0.0 0.0 71.4 4.4 3.4 5.0 10.4 0.0 4.7 0.3 0.1 0.0 3.0 2.4 0.5 0.0 12.8 0.1 0.4 0.0 0.2 0.0 0.0 26.3 4.7 20.4 2.1 4.8 0.2 2.7 0.0 0.4 0.6 0.0 0.1 ADAMTS7 "ADAM-TS7, DKFZp434H204" ENSG00000136378 "ADAM metallopeptidase with thrombospondin type 1 motif 7" Q9UKP4 15 78759206-78811464 "Plasma proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "heart muscle: 30.6" "Cell type enriched" "Detected in some" 4 "Theca cells: 44.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 9 "HMC-1: 259.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA045284, HPA048453" Uncertain Supported Vesicles "Secreted to extracellular matrix" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "HPA045284: AB_2679285, HPA048453: AB_2680399" "unprognostic (5.94e-3)" "unprognostic (9.94e-3)" "unprognostic (2.76e-2)" "unprognostic (7.09e-2)" "unprognostic (3.38e-1)" "unprognostic (1.93e-1)" "unprognostic (5.88e-4)" "unprognostic (3.34e-3)" "unprognostic (2.89e-2)" "unprognostic (3.31e-2)" "unprognostic (1.83e-2)" "unprognostic (3.79e-1)" "unprognostic (1.34e-2)" "prognostic unfavorable (9.53e-4)" "unprognostic (1.59e-1)" "unprognostic (2.66e-2)" "unprognostic (8.86e-2)" 6.6 5.3 0.5 1.8 0.4 0.1 3.8 0.3 0.5 6.0 0.6 4.2 1.1 7.2 0.1 0.9 2.2 2.3 30.6 0.4 0.5 2.2 1.1 6.3 0.9 0.5 0.5 6.1 0.5 0.4 0.8 2.1 0.4 1.8 0.2 0.5 1.3 0.4 1.1 1.8 2.6 1.4 0.2 5.2 2.2 4.1 0.7 0.1 2.1 0.5 0.2 3.0 2.5 0.6 0.0 1.1 16.5 7.5 6.9 8.2 20.9 3.7 1.3 1.0 0.6 0.0 0.1 0.0 4.8 0.4 1.0 0.4 0.4 2.0 0.0 0.3 0.6 2.1 0.5 0.1 6.9 0.0 259.9 3.3 2.0 1.9 1.0 5.3 24.0 0.0 0.3 0.7 5.6 0.0 0.1 4.9 4.7 0.0 1.4 17.3 7.7 0.3 0.5 0.9 0.3 23.9 4.8 0.0 0.6 4.0 3.2 0.4 29.8 9.4 1.0 3.3 0.0 0.1 0.0 0.0 1.6 0.1 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.3 0.5 0.4 0.5 0.5 0.5 0.4 0.2 0.7 0.6 7.5 0.0 0.0 3.6 0.3 0.4 0.2 0.7 0.0 0.3 0.1 0.5 9.8 0.0 0.3 0.0 0.0 0.3 0.2 0.1 0.0 0.1 4.9 0.8 7.5 10.5 0.0 0.0 0.1 0.0 0.3 10.1 0.5 0.9 3.8 7.2 2.9 0.3 0.7 0.0 0.2 0.0 2.0 0.0 0.8 2.7 1.5 0.1 1.8 1.0 0.1 1.3 0.0 9.5 1.4 0.3 0.0 1.9 0.0 0.3 0.0 0.1 0.3 0.1 0.0 3.7 5.0 2.6 2.0 0.2 0.1 0.3 0.5 44.9 0.1 0.3 ADAMTS9 KIAA1312 ENSG00000163638 "ADAM metallopeptidase with thrombospondin type 1 motif 9" Q9P2N4 3 64515654-64688000 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "ER-Golgi transport, Protein transport, Transport" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 41.2" "Cell type enhanced" "Detected in many" "Adipocytes: 166.3;Astrocytes: 84.2;Basal prostatic cells: 87.2;Endometrial stromal cells: 179.1;Endothelial cells: 221.0;Prostatic glandular cells: 115.7;Smooth muscle cells: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 23.6;RPTEC TERT1: 27.1;SH-SY5Y: 128.3;SuSa: 40.5;WM-115: 28.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028567, HPA028577, HPA028601" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" No NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "Endoplasmic reticulum" "HPA028567: AB_10599275, HPA028577: AB_10600330, HPA028601: AB_2672694" "unprognostic (2.21e-1)" "unprognostic (1.06e-1)" "unprognostic (1.41e-1)" "unprognostic (4.83e-2)" "unprognostic (3.08e-1)" "unprognostic (1.37e-2)" "unprognostic (7.80e-3)" "unprognostic (5.85e-2)" "unprognostic (2.77e-1)" "unprognostic (2.64e-1)" "unprognostic (1.11e-1)" "unprognostic (7.67e-2)" "unprognostic (3.16e-3)" "unprognostic (1.46e-2)" "unprognostic (3.01e-1)" "unprognostic (1.98e-3)" "unprognostic (5.00e-3)" 41.2 4.8 4.0 12.2 5.0 0.1 19.0 5.5 5.3 16.2 7.9 8.1 1.2 13.2 1.1 5.3 10.2 7.8 15.6 4.4 5.6 9.5 2.7 13.6 1.9 10.8 8.1 7.3 9.8 6.3 2.2 31.7 8.5 7.9 2.7 1.4 3.2 3.7 7.4 2.6 3.7 12.1 8.0 4.1 4.7 0.8 8.1 1.0 7.3 7.3 1.1 22.5 9.0 6.4 0.0 1.2 13.9 0.0 0.6 0.1 1.3 0.2 0.0 0.0 0.0 1.9 0.0 0.0 2.3 0.3 0.4 0.0 1.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.9 0.0 8.8 2.6 0.0 0.0 0.5 0.0 23.6 0.0 0.5 0.0 0.3 0.1 0.0 0.0 7.5 1.1 0.0 0.0 2.4 0.1 27.1 0.3 0.1 128.3 0.0 0.0 0.0 40.5 0.0 0.7 5.4 0.8 0.4 0.0 0.8 0.0 0.0 0.0 0.5 0.0 28.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 5.0 5.5 5.3 4.4 5.6 10.8 8.1 8.5 8.0 8.1 6.4 166.3 3.2 4.8 84.2 0.0 17.5 87.2 0.0 4.6 0.0 6.9 15.9 6.6 2.8 2.6 38.6 2.1 1.0 0.2 1.1 0.0 69.7 0.9 13.2 179.1 221.0 1.2 0.0 4.2 3.3 0.6 31.4 1.5 33.8 0.0 8.4 27.1 0.3 7.5 0.0 14.3 1.1 0.0 0.3 20.1 0.4 2.5 2.7 26.6 21.5 0.0 0.2 0.0 26.7 0.6 45.5 1.0 2.2 0.0 115.7 0.0 10.8 0.1 0.1 0.0 20.7 94.8 0.3 0.7 1.3 13.5 1.6 3.2 12.1 0.9 36.7 ADAMTSL1 "ADAMTSR1, C9orf94, FLJ35283" ENSG00000178031 "ADAMTS like 1" Q8N6G6 9 17906563-18910950 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 13.3" "Cell type enriched" "Detected in some" 6 "Excitatory neurons: 245.4" "Cancer enhanced" "Detected in many" "prostate cancer: 2.6" "Region enhanced" "Detected in many" "thalamus: 9.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 118.3;HSkMC: 61.2;hTEC/SVTERT24-B: 64.3;hTERT-RPE1: 55.8;LHCN-M2: 64.3;TIME: 207.9;U-138 MG: 96.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA057437, HPA074973" Uncertain Approved Vesicles "Secreted in other tissues" NA NA 28000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA057437: AB_2683440, HPA074973: " "unprognostic (4.64e-2)" "unprognostic (2.41e-1)" "unprognostic (3.95e-2)" "unprognostic (7.21e-2)" "unprognostic (2.45e-3)" "unprognostic (1.89e-1)" "unprognostic (1.52e-2)" "unprognostic (7.77e-2)" "unprognostic (2.01e-4)" "unprognostic (3.66e-2)" "unprognostic (1.21e-1)" "unprognostic (6.41e-2)" "unprognostic (7.29e-3)" "unprognostic (2.58e-2)" "unprognostic (1.87e-1)" "unprognostic (6.59e-2)" "unprognostic (1.50e-2)" 3.9 5.5 1.0 1.9 0.9 0.0 2.4 1.7 1.1 3.8 0.0 3.0 1.8 13.3 1.1 5.4 4.0 4.9 1.0 3.6 1.8 2.1 0.9 1.2 0.8 2.1 3.3 1.5 1.4 0.2 1.8 0.6 0.5 8.1 2.9 0.4 1.3 1.6 0.4 0.9 1.8 11.2 1.4 0.7 5.1 1.0 9.6 0.5 0.9 0.8 0.9 2.6 2.0 1.0 6.4 0.5 1.2 0.0 17.5 118.3 0.0 3.6 16.3 14.8 33.3 0.0 0.1 0.1 0.1 44.1 5.5 0.0 6.6 1.1 41.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 61.2 0.0 64.3 0.2 55.8 27.1 0.0 0.1 0.3 64.3 0.0 0.2 0.1 5.6 0.0 0.3 0.0 10.1 0.2 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 207.9 96.9 2.5 2.6 15.8 0.0 0.0 0.0 31.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 1.7 1.1 3.6 1.8 2.1 3.3 0.5 1.4 9.6 1.0 1.6 0.0 0.0 5.2 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.4 1.4 0.0 0.6 0.0 0.0 0.0 0.0 3.1 0.0 0.1 7.2 0.3 1.1 8.9 0.0 0.0 245.4 0.0 0.0 15.1 0.5 0.5 0.0 0.1 1.1 0.0 0.1 0.0 39.5 0.4 0.0 0.0 0.8 2.9 5.0 0.1 0.0 1.9 0.0 0.0 0.0 9.0 5.7 0.0 0.4 1.2 0.0 0.6 0.2 0.4 0.0 0.0 0.0 0.1 1.2 2.9 1.6 0.1 0.1 0.1 0.0 0.1 1.7 0.1 ADAMTSL2 KIAA0605 ENSG00000197859 "ADAMTS like 2" Q86TH1 9 133532164-133575519 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 73.2;liver: 35.8" "Cell type enhanced" "Detected in some" "Distal tubular cells: 5.9;Endothelial cells: 5.7;Fibroblasts: 8.5;Microglial cells: 12.2;Sertoli cells: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 7.4;RPMI-8226: 10.1;SH-SY5Y: 30.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045634, HPA053812" Approved Approved Vesicles "Secreted in other tissues" NA NA 170000000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA045634: AB_2679399, HPA053812: AB_2682271" "unprognostic (5.10e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (5.01e-4)" "unprognostic (8.35e-2)" "unprognostic (1.07e-1)" "unprognostic (5.50e-2)" "unprognostic (6.78e-3)" "unprognostic (1.31e-2)" "unprognostic (5.49e-2)" "unprognostic (1.35e-1)" "prognostic favorable (6.70e-4)" "unprognostic (5.17e-2)" "unprognostic (7.37e-2)" "unprognostic (1.56e-1)" "unprognostic (3.40e-1)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" 3.7 28.5 6.8 1.0 7.3 0.1 1.5 12.0 10.1 2.3 1.4 2.7 1.4 3.1 3.1 1.8 3.1 2.5 73.2 5.8 7.9 25.9 35.8 23.2 3.4 19.3 11.1 4.9 7.1 1.2 15.9 1.5 20.8 8.4 0.3 0.3 3.4 2.2 4.3 0.8 3.2 0.9 8.5 6.4 2.3 3.1 9.3 0.6 12.1 0.5 0.6 5.3 1.6 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.6 0.5 0.0 1.1 0.7 10.1 0.0 0.0 1.4 30.1 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 7.3 12.0 10.1 5.8 7.9 19.3 11.1 20.8 8.5 9.3 7.6 1.4 0.0 0.5 4.9 0.1 0.1 0.1 0.0 0.0 4.2 0.0 0.1 2.3 0.0 0.0 1.8 0.0 0.1 0.0 1.4 5.9 0.2 0.1 0.1 0.1 5.7 5.3 0.0 5.0 0.0 0.1 8.5 0.0 0.0 0.0 0.1 4.6 0.9 0.3 0.0 3.8 0.4 0.0 0.3 0.8 1.1 4.7 0.6 0.0 12.2 0.0 0.4 0.0 2.5 4.0 0.2 0.5 3.0 0.0 0.2 0.0 0.7 0.0 0.2 6.6 1.1 1.6 0.1 0.8 0.4 0.3 0.0 0.6 0.7 1.1 0.2 ADAMTSL3 "KIAA1233, punctin-2" ENSG00000156218 "ADAMTS like 3" P82987 15 83654088-84039842 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 141.1;Alveolar cells type 2: 111.8;Astrocytes: 86.5;Club cells: 61.7;granulocytes: 63.1;Inhibitory neurons: 91.6;Oligodendrocytes: 75.2;Respiratory ciliated cells: 56.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "EFO-21: 12.1;hTERT-RPE1: 3.6;RPTEC TERT1: 14.0;TIME: 13.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034773, HPA034774" Uncertain Uncertain Vesicles "Secreted in other tissues" NA NA 270000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA034773: AB_10601965, HPA034774: AB_2674326" "unprognostic (2.20e-1)" "unprognostic (1.37e-1)" "unprognostic (2.98e-2)" "unprognostic (1.07e-2)" "unprognostic (1.56e-1)" "unprognostic (9.89e-2)" "unprognostic (4.07e-2)" "unprognostic (3.27e-1)" "unprognostic (9.18e-3)" "unprognostic (5.92e-2)" "unprognostic (9.97e-2)" "unprognostic (3.85e-1)" "unprognostic (8.59e-3)" "unprognostic (5.00e-3)" "unprognostic (4.62e-1)" "unprognostic (8.64e-2)" "unprognostic (3.95e-5)" 6.3 4.2 1.1 1.0 1.7 0.0 1.7 1.4 1.0 3.1 4.4 10.6 1.4 6.9 1.5 3.3 4.4 1.1 10.7 1.1 1.1 3.3 10.4 7.4 1.1 1.4 1.5 1.2 7.3 0.8 1.4 10.4 1.7 6.6 3.2 0.3 2.4 7.1 2.6 1.4 1.8 4.7 1.5 1.9 4.6 2.7 1.1 1.0 2.6 4.8 0.5 5.2 2.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.9 0.0 14.0 0.0 0.0 0.0 0.2 0.2 0.0 1.3 0.0 0.0 13.3 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.7 1.4 1.0 1.1 1.1 1.4 1.5 1.7 1.5 1.1 3.0 8.7 141.1 111.8 86.5 0.1 7.0 5.2 1.7 0.6 0.2 0.2 0.3 9.4 0.0 61.7 1.8 0.0 0.1 0.8 0.0 0.0 0.5 14.9 0.6 0.4 10.6 0.0 0.0 31.3 2.4 0.2 29.0 1.5 1.2 63.1 0.1 1.1 10.2 0.2 6.7 91.6 0.0 0.0 0.6 0.5 16.9 49.4 5.9 0.0 5.6 0.0 0.1 1.0 4.5 75.2 1.0 0.0 17.0 0.4 2.4 0.0 0.6 56.4 0.2 26.3 13.0 8.3 2.1 2.8 0.6 1.1 0.1 5.0 0.4 0.0 2.3 ADCYAP1R1 "PAC1, PAC1R, PACAPR" ENSG00000078549 "ADCYAP receptor type I" P41586 7 31052308-31111479 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 148.0" "Group enriched" "Detected in some" 4 "Astrocytes: 57.1;Inhibitory neurons: 45.7" "Cancer enriched" "Detected in some" 11 "glioma: 45.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 3.7;NTERA-2: 4.8;SCLC-21H: 4.1;SH-SY5Y: 7.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030739, HPA049877" Enhanced Enhanced Vesicles NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA030739: AB_2732461, HPA049877: AB_2680928" "unprognostic (5.43e-2)" "unprognostic (1.16e-1)" "unprognostic (2.16e-2)" "prognostic favorable (5.78e-4)" "unprognostic (2.17e-1)" "unprognostic (8.36e-2)" "unprognostic (4.93e-2)" "unprognostic (5.75e-2)" "unprognostic (3.50e-2)" "unprognostic (3.88e-1)" "unprognostic (1.58e-1)" "unprognostic (6.67e-3)" "unprognostic (6.43e-4)" "unprognostic (1.09e-3)" "unprognostic (9.55e-2)" "unprognostic (3.85e-2)" "unprognostic (2.75e-4)" 7.4 11.4 91.8 2.3 79.8 0.0 4.0 53.4 57.6 13.1 3.5 7.1 0.8 5.3 1.5 2.9 29.5 1.3 3.8 69.7 106.5 0.1 0.2 0.8 0.1 96.0 102.7 1.8 1.6 1.6 9.8 0.0 88.9 1.8 1.3 2.7 2.2 3.2 1.3 1.1 2.2 3.7 67.9 0.5 3.5 1.6 148.0 0.8 2.1 8.0 0.8 1.8 4.3 43.7 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 7.4 0.0 0.0 0.0 1.4 0.0 0.0 0.2 0.6 0.8 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 91.8 79.8 53.4 57.6 69.7 106.5 96.0 102.7 88.9 67.9 148.0 43.7 4.2 0.0 0.0 57.1 0.0 0.5 0.0 0.0 0.0 1.7 0.2 0.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.2 0.7 0.0 0.0 10.8 0.0 0.0 4.6 0.0 6.3 0.0 1.2 0.0 0.0 0.0 0.0 45.7 0.0 0.0 0.0 0.7 0.9 11.5 0.0 1.8 2.8 0.0 0.0 0.0 11.6 1.5 0.0 0.0 5.7 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 5.8 0.3 1.5 0.0 0.3 0.0 0.2 0.1 0.0 0.1 ADGRE2 "CD312, EMR2" ENSG00000127507 "Adhesion G protein-coupled receptor E2" Q9UHX3 19 14732392-14778560 "CD markers, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Cell adhesion, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.4" "Group enriched" "Detected in many" 4 "granulocytes: 47.9;Kupffer cells: 69.4;Macrophages: 73.2;monocytes: 49.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 70.0;eosinophil: 74.7;intermediate monocyte: 46.9;neutrophil: 55.7;non-classical monocyte: 89.9" "Group enriched" "Detected in many" 9 "granulocytes: 74.7;monocytes: 89.9" "Cell line enhanced" "Detected in many" "HEL: 11.8;HMC-1: 18.3;NB-4: 11.5;RPMI-8226: 8.4;U-937: 14.9" "Low region specificity" "Detected in many" HPA055200 Uncertain Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles Cytosol "HPA055200: " "unprognostic (2.46e-2)" "unprognostic (3.58e-2)" "unprognostic (2.21e-1)" "unprognostic (1.66e-1)" "unprognostic (9.10e-2)" "unprognostic (3.58e-2)" "unprognostic (2.77e-2)" "unprognostic (3.88e-2)" "unprognostic (4.28e-1)" "unprognostic (1.22e-1)" "unprognostic (2.32e-1)" "unprognostic (2.70e-2)" "prognostic unfavorable (4.35e-6)" "unprognostic (1.46e-1)" "unprognostic (2.45e-3)" "unprognostic (2.50e-1)" "unprognostic (1.01e-1)" 4.9 1.5 1.0 19.4 1.3 6.9 1.8 1.2 2.1 0.9 1.3 1.4 1.9 0.7 0.7 0.9 0.9 2.5 0.5 1.0 1.5 2.1 2.0 4.2 3.0 2.5 1.6 0.1 0.8 1.1 0.5 1.6 2.2 1.1 1.9 0.6 1.0 2.8 0.6 2.0 2.3 1.6 1.1 15.6 1.5 0.4 1.8 2.4 0.6 0.9 2.2 5.4 0.9 2.4 0.3 1.2 0.1 0.2 0.0 0.3 1.2 0.9 1.3 0.0 0.0 0.2 0.2 0.1 0.1 0.7 2.3 1.9 0.3 0.1 0.0 0.2 0.2 11.8 3.8 0.2 0.5 4.3 18.3 0.9 1.6 4.1 0.6 0.1 0.1 1.0 2.7 0.4 1.3 0.5 1.5 11.5 0.4 0.8 0.2 0.1 1.5 8.4 0.0 0.3 0.0 0.2 2.4 2.0 0.4 0.2 0.3 5.4 0.3 0.3 0.2 0.2 0.1 0.2 0.1 0.2 1.1 14.9 0.6 70.0 13.9 74.7 0.2 46.9 0.2 0.2 0.2 0.1 9.3 0.3 0.1 0.2 55.7 3.3 89.9 1.9 0.1 7.3 1.0 1.3 1.2 2.1 1.0 1.5 2.5 1.6 2.2 1.1 1.8 2.4 0.6 3.2 7.7 0.7 1.9 0.0 4.8 0.0 0.6 0.8 1.6 1.5 0.8 0.0 2.5 0.0 0.0 0.2 12.8 0.0 0.0 0.0 2.0 0.7 3.5 1.8 1.2 3.8 0.9 0.0 0.5 1.9 1.1 0.9 47.9 0.1 0.7 0.5 12.8 0.0 1.2 0.1 0.0 69.4 0.0 2.5 0.0 73.2 0.0 0.0 49.2 0.0 2.1 0.5 12.0 0.0 0.2 0.4 2.1 2.4 0.1 0.1 2.2 0.9 0.0 2.0 1.5 0.3 0.5 0.6 0.0 0.4 3.0 0.1 0.1 3.0 ADGRG5 "GPR114, PGR27" ENSG00000159618 "Adhesion G protein-coupled receptor G5" Q8IZF4 16 57542643-57591681 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 3.9;lymphoid tissue: 10.5" "Cell type enhanced" "Detected in some" "dendritic cells: 32.0;Microglial cells: 11.2;NK-cells: 43.3;Plasma cells: 16.4;T-cells: 7.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "eosinophil: 125.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HMC-1: 39.4;OE19: 13.2;RPMI-8226: 6.2;THP-1: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA007133 Enhanced Approved "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear membrane, Vesicles" Nucleoplasm "HPA007133: AB_1849253" "unprognostic (6.11e-3)" "prognostic favorable (4.25e-4)" "unprognostic (2.70e-1)" "unprognostic (2.27e-2)" "unprognostic (6.14e-2)" "unprognostic (1.14e-2)" "unprognostic (6.43e-2)" "unprognostic (1.42e-2)" "unprognostic (8.09e-4)" "unprognostic (3.80e-3)" "unprognostic (3.02e-3)" "unprognostic (1.91e-1)" "unprognostic (4.37e-3)" "unprognostic (7.69e-3)" "unprognostic (4.52e-1)" "unprognostic (1.62e-3)" "unprognostic (6.32e-3)" 0.3 0.3 0.3 5.0 0.2 1.4 0.7 0.2 0.2 0.2 0.1 1.7 3.7 0.3 0.1 0.6 0.5 0.1 0.0 0.3 0.4 0.0 0.2 0.9 10.5 0.8 0.4 0.0 0.0 0.1 0.2 0.0 0.6 0.3 1.3 0.0 1.3 0.3 0.1 0.1 3.9 0.3 0.6 5.8 0.4 0.4 0.4 1.6 0.3 0.0 10.5 1.4 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 2.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.4 39.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.0 0.0 3.6 3.6 13.2 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.2 0.1 125.9 33.3 0.1 16.9 12.0 4.8 19.1 2.4 8.6 1.2 11.2 0.5 29.9 0.1 68.8 0.2 9.0 0.3 0.2 0.2 0.2 0.3 0.4 0.8 0.4 0.6 0.6 0.4 0.3 0.3 0.0 1.3 0.3 5.0 0.0 0.1 0.0 0.0 0.0 0.1 0.6 0.8 0.0 0.0 0.0 0.0 0.2 32.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.3 0.0 0.6 0.0 0.3 0.0 3.2 0.0 11.2 1.7 0.0 43.3 0.0 0.3 0.0 0.0 0.0 16.4 0.1 2.9 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.2 0.0 0.0 7.1 0.0 0.7 0.0 ADHFE1 FLJ32430 ENSG00000147576 "Alcohol dehydrogenase iron containing 1" Q8IWW8 8 66432492-66468907 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 31.2;skeletal muscle: 29.2;tongue: 31.3" "Cell type enhanced" "Detected in many" "Astrocytes: 76.4;Cardiomyocytes: 41.6;Syncytiotrophoblasts: 116.4" "Cancer enhanced" "Detected in many" "liver cancer: 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.2;RPTEC TERT1: 1.5" "Low region specificity" "Detected in all" HPA023062 Enhanced Approved Vesicles NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA023062: AB_1844611" "prognostic favorable (5.76e-5)" "unprognostic (8.69e-2)" "unprognostic (6.71e-2)" "unprognostic (2.70e-1)" "unprognostic (1.14e-1)" "unprognostic (1.22e-1)" "prognostic favorable (9.90e-5)" "unprognostic (7.76e-3)" "unprognostic (2.88e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (9.43e-2)" "prognostic favorable (4.55e-5)" "unprognostic (1.37e-2)" "unprognostic (2.06e-1)" "unprognostic (4.66e-2)" "unprognostic (5.94e-3)" 7.0 2.3 8.7 0.3 8.5 0.0 3.9 7.2 11.7 2.3 10.4 3.9 0.6 2.0 1.3 1.3 5.6 0.7 24.5 8.2 8.2 6.6 31.2 2.1 0.3 8.3 8.5 5.1 9.4 5.0 2.6 1.1 8.1 5.2 0.7 1.5 2.3 1.5 29.2 1.1 2.5 0.2 7.8 1.8 11.0 1.7 8.7 0.3 2.7 31.3 0.3 4.4 1.8 8.5 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.2 0.0 0.2 0.0 0.5 0.1 0.0 0.3 0.0 0.4 0.1 0.3 0.0 0.7 0.0 0.0 0.0 0.0 8.7 8.5 7.2 11.7 8.2 8.2 8.3 8.5 8.1 7.8 8.7 8.5 1.5 9.6 20.1 76.4 1.8 1.0 4.1 2.7 3.4 1.7 4.6 4.6 41.6 14.3 9.6 9.2 10.4 8.8 6.5 1.0 11.7 1.5 0.5 2.5 1.6 3.3 3.6 2.5 8.3 0.6 0.9 5.3 8.6 2.5 8.8 6.1 6.1 27.1 2.5 0.0 13.2 2.0 4.1 2.1 2.8 1.6 23.9 2.1 0.0 14.0 2.0 7.6 6.2 21.6 19.2 0.9 5.8 27.1 3.0 3.5 4.1 14.8 14.3 8.5 0.0 7.8 5.2 0.5 0.6 1.9 1.0 116.4 10.0 2.5 2.4 2.5 ADRA1A "ADRA1C, ADRA1L1" ENSG00000120907 "Adrenoceptor alpha 1A" P35348 8 26748150-26867278 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.6;liver: 60.1" "Cell type enhanced" "Detected in some" "Astrocytes: 105.4;Early spermatids: 51.3;Inhibitory neurons: 123.2;Late spermatids: 28.3;Oligodendrocyte precursor cells: 114.1" "Cancer enhanced" "Detected in some" "liver cancer: 0.9;prostate cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029678, HPA029679, HPA076693" Approved Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 15: Liver - Metabolism" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Vesicles" "HPA029678: AB_10602108, HPA029679: AB_2673143, HPA076693: " "unprognostic (1.27e-1)" "unprognostic (1.68e-2)" "unprognostic (1.99e-1)" "unprognostic (3.57e-1)" "unprognostic (5.04e-4)" "unprognostic (1.97e-1)" "unprognostic (9.55e-2)" "unprognostic (3.08e-1)" "unprognostic (1.58e-2)" "unprognostic (7.47e-2)" "unprognostic (1.71e-2)" "unprognostic (6.06e-3)" "unprognostic (7.41e-2)" "unprognostic (1.52e-2)" "unprognostic (1.30e-1)" 21.8 0.5 13.3 1.1 11.1 0.0 3.6 3.0 22.6 0.7 0.0 1.4 0.9 1.4 0.6 0.8 0.2 0.3 7.6 42.6 20.8 0.7 60.1 3.9 1.7 9.3 4.9 0.9 0.0 0.0 0.1 0.0 9.5 12.4 0.5 0.3 6.2 13.5 0.2 0.6 1.1 2.9 1.5 9.2 0.9 0.1 4.2 0.1 0.1 1.4 0.4 0.4 0.3 6.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 11.1 3.0 22.6 42.6 20.8 9.3 4.9 9.5 1.5 4.2 6.9 0.0 0.0 0.0 105.4 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 51.3 0.0 0.0 0.1 0.0 0.0 15.5 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.7 16.2 0.0 0.0 123.2 0.0 0.0 0.0 0.5 28.3 0.6 0.0 0.0 9.4 0.0 0.0 0.0 114.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 ADRA2B "ADRA2L1, ADRA2RL1, ADRARL1" ENSG00000274286 "Adrenoceptor alpha 2B" P18089 2 96112876-96116571 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 9.0;Langerhans cells: 8.0;Sertoli cells: 32.9;Smooth muscle cells: 13.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.5;EFO-21: 1.0" "Group enriched" "Detected in some" 6 "basal ganglia: 2.5;cerebellum: 1.0;thalamus: 3.2" "Low region specificity" "Detected in some" "HPA066029, HPA074948" Approved Supported Vesicles,Cytosol NA NA "Cluster 18: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles Cytosol "HPA066029: AB_2685599, HPA074948: " "unprognostic (6.16e-2)" "unprognostic (1.31e-2)" "unprognostic (1.76e-2)" "unprognostic (4.93e-4)" "unprognostic (1.84e-2)" "unprognostic (5.24e-2)" "unprognostic (6.80e-5)" "unprognostic (4.85e-2)" "unprognostic (1.69e-1)" "unprognostic (3.16e-2)" "unprognostic (8.34e-2)" "unprognostic (2.54e-1)" "unprognostic (2.21e-1)" "unprognostic (4.43e-2)" "unprognostic (3.39e-1)" "unprognostic (1.36e-1)" "unprognostic (6.55e-2)" 6.4 2.1 1.5 0.3 1.7 0.8 3.0 1.4 2.7 1.5 4.9 2.3 0.3 1.9 3.8 0.7 3.0 0.6 10.1 1.2 1.4 5.1 7.0 0.5 0.2 1.8 1.6 1.7 0.8 0.5 0.5 0.8 1.7 1.4 0.3 0.0 2.2 1.5 6.4 1.9 2.6 0.7 1.3 8.6 2.2 1.6 2.6 0.2 1.3 5.0 0.1 2.5 1.8 2.4 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.7 1.4 2.7 1.2 1.4 1.8 1.6 1.7 1.3 2.6 2.4 2.9 0.0 0.0 0.0 0.9 1.1 0.7 0.7 0.6 0.0 0.9 0.9 2.5 0.0 1.5 1.8 0.0 0.8 2.9 0.1 0.0 0.2 0.0 2.2 1.0 2.4 2.4 0.0 0.0 0.6 0.2 1.0 1.1 9.0 0.0 0.0 2.5 0.0 0.3 0.0 0.0 0.2 0.0 0.3 8.0 0.0 1.8 5.1 1.8 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.4 0.4 0.7 0.0 0.1 1.4 0.0 32.9 0.7 13.3 0.0 0.3 0.6 1.4 0.4 2.8 0.1 0.1 0.3 AEBP1 ACLP ENSG00000106624 "AE binding protein 1" Q8IUX7 7 44104345-44114562 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Calmodulin-binding, DNA-binding, Repressor" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 103.0;Fibroblasts: 263.2;Leydig cells: 151.6;Peritubular cells: 508.9;Smooth muscle cells: 173.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 7.6" "Lineage enriched" "Detected in many" 5 "dendritic cells: 7.6" "Cell line enhanced" "Detected in many" "ASC diff: 141.1;BJ: 193.0;BJ hTERT+: 126.0;fHDF/TERT166: 208.9;JURKAT: 145.0;WM-115: 117.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 57.6" "CAB009966, HPA047724, HPA063595, HPA064970" Supported Supported Nucleoplasm,Vesicles,Cytosol "Secreted - unknown location" NA NA 2700000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "CAB009966: AB_2225690, HPA047724: AB_2680132, HPA063595: AB_2685052, HPA064970: AB_2685394" "unprognostic (1.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.66e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.13e-1)" "unprognostic (7.00e-2)" "unprognostic (8.79e-2)" "unprognostic (2.52e-1)" "unprognostic (3.27e-2)" "unprognostic (1.26e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (9.31e-9)" "unprognostic (2.88e-3)" "unprognostic (9.58e-2)" "unprognostic (1.17e-2)" "unprognostic (6.28e-3)" 190.5 59.9 45.0 59.8 56.0 10.6 153.0 38.6 44.8 312.1 28.0 95.3 19.2 268.8 59.6 65.7 199.8 155.9 156.7 47.3 92.9 68.7 20.3 166.0 45.5 114.7 81.5 253.7 28.9 10.1 43.3 89.0 79.6 112.1 25.0 1.3 50.7 213.5 21.3 84.8 79.1 119.3 74.3 54.4 71.2 40.4 52.1 73.3 83.7 14.1 16.7 138.7 198.0 66.6 0.6 0.0 44.5 0.1 141.1 49.6 1.0 193.0 126.0 21.6 4.5 0.0 0.1 5.3 20.9 208.9 0.2 0.1 2.4 3.5 9.1 0.6 0.0 13.3 0.1 0.0 39.6 0.1 0.3 75.8 0.0 72.9 0.1 1.1 9.7 145.0 8.3 0.3 0.0 0.2 86.9 16.1 19.1 0.0 0.4 71.3 1.7 1.7 5.0 0.0 4.9 25.3 0.1 0.3 85.9 41.9 0.4 14.4 34.1 0.0 86.2 0.5 0.3 1.0 0.9 102.8 0.4 0.2 117.9 0.0 0.0 0.0 0.3 0.0 0.2 1.5 0.2 0.0 0.0 1.4 0.9 0.5 0.0 0.1 0.0 7.6 0.0 0.3 45.0 56.0 38.6 44.8 47.3 92.9 114.7 81.5 79.6 74.3 52.1 66.6 23.6 0.0 2.5 32.3 11.8 34.5 5.7 1.3 1.8 0.8 2.0 14.6 26.4 1.5 1.4 7.3 0.0 2.0 22.7 0.0 0.0 0.9 3.1 3.3 103.0 18.0 0.0 1.3 0.1 0.0 3.3 263.2 8.6 2.9 2.5 33.3 30.4 0.6 3.6 0.0 0.3 0.0 0.0 1.8 42.0 18.0 151.6 3.2 85.4 17.8 1.0 0.2 1.0 6.0 0.3 0.4 0.0 508.9 9.7 16.9 0.0 2.2 2.2 0.8 39.5 23.6 173.4 4.0 4.6 1.5 27.4 3.4 4.8 28.7 0.0 2.4 AFTPH "FLJ20080, FLJ23793, MGC33965, Nbla10388" ENSG00000119844 Aftiphilin Q6ULP2 2 64524305-64593005 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034990, HPA034991" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Cytosol "Golgi apparatus, Vesicles" "HPA034990: AB_2674398, HPA034991: AB_10603577" "unprognostic (7.30e-2)" "unprognostic (4.72e-2)" "unprognostic (9.16e-2)" "unprognostic (8.54e-2)" "unprognostic (3.24e-1)" "unprognostic (4.25e-2)" "unprognostic (2.54e-2)" "unprognostic (1.75e-2)" "unprognostic (1.52e-1)" "unprognostic (8.44e-2)" "unprognostic (3.42e-2)" "unprognostic (4.65e-2)" "prognostic favorable (2.37e-5)" "prognostic favorable (8.44e-4)" "unprognostic (3.12e-1)" "unprognostic (1.74e-1)" "prognostic favorable (1.83e-4)" 15.9 20.2 24.6 21.1 24.9 21.3 32.4 31.2 38.4 22.5 28.3 30.5 23.1 18.8 43.7 29.6 22.9 21.9 12.0 25.3 25.6 56.1 33.6 21.9 37.2 24.6 24.6 19.3 31.6 38.0 25.1 15.0 24.5 34.5 33.7 36.8 28.9 18.6 15.4 33.2 24.5 17.3 24.8 26.4 33.7 24.6 25.4 29.3 25.3 12.9 41.4 25.5 22.4 26.2 29.8 19.3 14.1 17.1 17.8 15.1 23.4 16.7 24.9 26.9 20.1 22.4 21.9 43.9 16.0 20.7 31.1 23.5 24.6 23.3 34.8 42.8 13.5 21.0 12.0 26.5 18.8 40.5 34.5 7.5 48.6 17.4 39.6 19.8 21.4 21.8 16.0 38.7 16.8 16.9 21.9 49.1 13.0 55.9 14.3 17.7 22.6 28.8 48.9 31.5 25.9 13.1 17.7 39.9 35.7 18.0 24.0 30.6 18.5 20.0 23.0 17.0 18.8 43.3 27.8 66.7 15.1 45.3 22.6 40.5 9.3 16.6 7.4 9.3 8.7 21.8 9.3 9.1 12.2 20.3 8.8 6.9 16.3 7.1 14.7 15.8 12.8 5.9 24.6 24.9 31.2 38.4 25.3 25.6 24.6 24.6 24.5 24.8 25.4 26.2 24.6 25.6 39.7 43.1 75.4 122.6 29.6 21.5 55.8 24.2 43.8 23.0 16.0 40.0 33.6 20.2 20.9 13.8 40.5 60.7 37.2 25.5 34.8 44.6 17.8 27.1 46.6 52.0 72.1 25.7 12.4 23.6 35.2 55.9 46.9 17.8 17.5 36.8 20.8 37.0 62.9 40.3 20.3 45.2 77.9 55.1 15.8 52.1 23.2 65.6 60.8 35.0 26.8 52.3 67.0 27.3 43.0 20.7 60.5 42.6 29.0 70.5 40.2 32.9 26.3 25.3 21.2 43.1 21.9 59.0 123.5 27.2 36.5 10.2 40.3 46.1 AGFG1 "HRB, RAB, RIP" ENSG00000173744 "ArfGAP with FG repeats 1" P52594 2 227472152-227561217 "Predicted intracellular proteins" "Differentiation, mRNA transport, Spermatogenesis, Transport" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 333.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008741 Approved Supported Vesicles NA NA 120000 "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA008741: AB_1850752" "unprognostic (5.76e-2)" "prognostic unfavorable (7.13e-4)" "unprognostic (8.73e-3)" "unprognostic (6.31e-3)" "prognostic favorable (6.10e-4)" "unprognostic (9.30e-3)" "prognostic unfavorable (7.31e-6)" "prognostic unfavorable (1.85e-4)" "unprognostic (1.30e-1)" "prognostic unfavorable (3.43e-5)" "unprognostic (2.03e-2)" "unprognostic (5.78e-2)" "prognostic unfavorable (6.92e-4)" "unprognostic (1.25e-1)" "unprognostic (2.37e-1)" "unprognostic (1.98e-1)" "unprognostic (4.24e-3)" 69.4 39.4 30.4 48.4 31.6 155.5 51.1 29.3 36.0 25.3 23.8 32.2 43.4 25.7 20.1 47.2 27.3 38.9 36.2 32.4 27.0 36.9 36.2 54.6 47.1 34.6 29.0 26.1 35.0 41.6 17.9 75.8 33.4 21.0 33.0 47.7 27.9 23.4 33.9 36.3 36.2 39.3 33.6 46.5 33.2 92.8 34.5 48.6 34.3 38.6 53.3 65.7 32.2 47.3 60.5 97.9 50.8 49.6 84.8 62.1 191.6 78.4 74.6 92.0 81.2 77.4 67.6 42.7 58.3 86.8 123.8 62.2 87.9 101.7 118.6 72.3 48.9 94.1 80.8 144.3 90.9 64.7 57.0 38.3 106.4 116.7 109.5 70.3 93.7 43.3 100.3 112.0 111.8 85.8 77.8 58.0 79.3 80.4 50.4 70.8 83.6 30.3 91.7 81.5 47.0 36.7 64.1 82.5 74.7 87.6 35.3 72.4 92.7 78.8 63.0 114.7 70.0 64.5 46.9 59.6 85.6 54.4 92.5 4.1 5.3 1.9 1.6 4.3 3.2 2.0 1.8 1.5 3.3 3.5 1.5 2.8 5.6 1.1 4.2 2.3 2.3 1.6 30.4 31.6 29.3 36.0 32.4 27.0 34.6 29.0 33.4 33.6 34.5 47.3 36.6 25.6 23.6 45.7 27.2 33.1 37.5 18.0 18.2 37.7 29.3 22.1 23.3 17.2 19.6 22.0 25.0 31.0 26.5 28.2 15.6 17.5 162.3 32.7 34.9 29.1 34.1 13.3 114.2 21.5 17.5 26.8 39.8 65.8 12.7 30.4 23.6 22.9 24.1 43.7 74.9 20.4 12.2 92.8 33.6 333.2 15.5 67.3 19.6 119.9 48.4 43.3 19.6 109.6 116.0 32.6 18.0 11.7 22.7 39.4 31.3 27.4 15.5 35.4 19.7 83.8 21.7 72.6 18.4 25.0 32.1 39.7 24.0 20.6 22.2 57.9 AGK "FLJ10842, MULK" ENSG00000006530 "Acylglycerol kinase" Q53H12 7 141551278-141655244 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Cardiomyopathy, Cataract, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 43.4;Inhibitory neurons: 43.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 97.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020959, HPA053471" Supported Supported Vesicles,Mitochondria "Intracellular and membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Mitochondria Vesicles "HPA020959: AB_1854206, HPA053471: AB_2682164" "unprognostic (1.11e-1)" "unprognostic (1.43e-1)" "unprognostic (2.79e-1)" "unprognostic (1.28e-2)" "unprognostic (9.47e-3)" "unprognostic (5.43e-2)" "unprognostic (2.15e-2)" "unprognostic (3.68e-2)" "unprognostic (2.03e-1)" "unprognostic (3.43e-2)" "unprognostic (1.14e-1)" "unprognostic (6.24e-3)" "unprognostic (7.90e-2)" "unprognostic (9.29e-2)" "unprognostic (9.65e-2)" "unprognostic (3.30e-1)" "unprognostic (1.18e-1)" 10.1 14.7 9.4 8.5 10.9 5.6 11.9 8.3 12.8 11.5 10.2 11.8 5.9 11.7 14.5 12.2 12.2 7.8 30.4 11.1 10.8 15.7 14.1 11.6 12.1 8.0 8.8 11.3 10.1 21.5 13.7 10.0 9.0 12.8 13.1 12.7 13.7 11.4 8.6 9.6 12.0 15.4 8.2 16.6 12.2 6.6 10.0 14.0 12.7 10.0 14.7 10.8 11.5 9.0 23.7 25.6 26.7 21.8 21.2 29.4 16.2 23.5 29.3 44.5 50.9 24.7 18.3 26.3 24.0 26.8 40.5 18.7 41.6 32.8 51.0 33.8 32.7 26.1 10.7 18.7 34.1 15.6 12.5 29.9 26.9 36.3 33.1 19.8 34.1 32.3 36.3 36.9 25.3 24.6 47.3 9.1 25.6 19.9 32.4 29.2 4.2 80.1 33.1 20.8 23.3 29.6 24.6 29.7 27.1 26.1 16.3 20.2 19.5 18.9 14.1 23.8 38.1 29.5 31.9 14.4 30.7 9.1 50.4 0.4 7.1 1.2 22.1 13.9 15.3 10.8 17.3 26.0 16.2 6.5 12.8 23.5 1.2 97.3 8.2 6.3 18.9 15.7 9.4 10.9 8.3 12.8 11.1 10.8 8.0 8.8 9.0 8.2 10.0 9.0 8.4 0.0 6.0 22.5 11.4 3.1 5.6 7.9 5.2 11.8 5.5 5.1 18.1 2.8 6.6 12.9 8.4 15.7 15.8 3.0 9.8 6.6 9.9 7.4 9.0 7.5 0.0 11.8 43.4 6.9 8.2 7.7 10.7 6.6 8.2 9.9 4.2 4.1 7.0 15.2 43.0 3.9 12.2 5.1 4.9 12.0 6.8 5.6 7.2 26.2 12.4 11.2 27.8 38.7 37.9 6.1 2.1 10.5 22.1 2.9 2.4 8.2 7.6 17.4 0.0 6.2 8.0 6.2 4.9 11.3 2.7 9.2 15.0 14.2 5.6 3.8 AGMO "FLJ16237, TMEM195" ENSG00000187546 "Alkylglycerol monooxygenase" Q6ZNB7 7 15200317-15562015 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 122.5" "Cell type enhanced" "Detected in some" "Hepatocytes: 83.0;Oligodendrocyte precursor cells: 33.7;Oligodendrocytes: 38.5;Proximal enterocytes: 30.5;Proximal tubular cells: 16.9" "Cancer enriched" "Detected in many" 5 "liver cancer: 15.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.4" "Cell line enhanced" "Detected in some" "HSkMC: 3.5;Karpas-707: 7.7;NTERA-2: 3.5;SCLC-21H: 3.2;TIME: 4.0;WM-115: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057900 Uncertain Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 17: WM-115 - Nervous system development" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA057900: " "unprognostic (2.82e-1)" "unprognostic (9.28e-2)" "unprognostic (5.60e-3)" "unprognostic (1.44e-4)" "unprognostic (7.52e-2)" "unprognostic (1.07e-2)" "unprognostic (3.61e-2)" "unprognostic (6.56e-2)" "unprognostic (3.31e-1)" "unprognostic (3.35e-1)" "unprognostic (4.18e-3)" "unprognostic (3.24e-1)" "unprognostic (1.64e-1)" "unprognostic (2.04e-2)" "unprognostic (3.45e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" 2.8 0.1 0.9 0.6 2.4 0.1 1.8 0.7 1.9 0.1 0.1 1.2 9.7 0.1 14.5 0.1 0.1 3.6 0.4 0.7 1.4 8.9 122.5 0.2 0.5 1.5 1.4 0.1 0.1 0.0 0.4 0.8 1.5 0.0 0.6 0.1 0.2 0.1 0.3 0.2 14.9 0.1 0.9 0.0 0.3 3.0 1.8 0.2 0.4 0.4 0.1 1.2 0.1 4.1 0.0 2.2 0.0 1.9 0.2 2.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.1 3.5 0.0 0.0 0.0 0.0 1.2 0.0 0.7 3.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 4.0 1.3 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 15.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.9 2.4 0.7 1.9 0.7 1.4 1.5 1.4 1.5 0.9 1.8 4.1 10.0 0.0 0.0 6.8 0.3 0.1 0.1 0.7 0.0 0.0 0.2 0.3 0.1 11.5 0.4 3.7 0.0 0.1 0.1 0.5 0.0 0.0 1.3 0.3 0.1 1.2 1.8 2.7 1.3 0.0 0.2 1.2 0.0 0.0 0.0 0.0 1.1 83.0 0.1 0.0 1.7 0.4 0.0 1.6 0.5 1.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 33.7 38.5 0.9 0.1 0.0 0.0 0.0 30.5 16.9 0.3 0.0 6.6 0.4 2.4 1.7 6.4 0.1 0.0 0.1 0.2 0.1 0.6 0.0 AGPAT4 "dJ473J16.2, LPAAT-delta" ENSG00000026652 "1-acylglycerol-3-phosphate O-acyltransferase 4" Q9NRZ5 6 161129967-161274061 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 51.3" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 407.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 25.5;HEL: 19.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053287, HPA060525" Approved Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "Nucleoli, Vesicles" "HPA053287: AB_2682101, HPA060525: AB_2684306" "unprognostic (5.69e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.73e-1)" "unprognostic (3.43e-2)" "unprognostic (4.14e-2)" "unprognostic (6.67e-3)" "unprognostic (1.94e-4)" "unprognostic (1.05e-1)" "unprognostic (3.42e-2)" "unprognostic (2.77e-2)" "unprognostic (1.76e-3)" "unprognostic (1.67e-1)" "prognostic unfavorable (4.08e-4)" "unprognostic (1.82e-2)" "unprognostic (8.87e-2)" "unprognostic (3.63e-4)" "unprognostic (5.51e-2)" 4.8 2.1 14.7 1.8 30.5 5.2 4.5 24.6 22.5 7.2 5.6 6.4 1.2 7.8 2.2 3.7 6.1 4.2 2.6 14.9 22.7 6.0 0.8 6.7 0.9 47.1 26.3 7.4 2.1 0.3 11.4 8.7 34.3 3.6 2.1 2.2 2.7 2.4 1.0 2.3 2.6 4.7 25.5 4.6 2.3 2.8 28.6 1.3 4.1 1.0 1.0 3.0 5.0 51.3 0.5 1.0 25.5 5.1 4.7 9.5 1.1 0.9 0.3 1.9 3.2 1.5 4.6 0.7 1.8 4.2 11.8 0.5 4.8 4.0 1.8 2.9 8.1 19.4 4.9 0.1 3.7 0.2 2.8 11.4 1.9 5.0 2.7 9.1 6.1 3.1 9.8 8.9 2.4 0.0 1.4 2.2 6.2 0.0 9.7 0.0 1.1 0.5 5.6 0.4 14.8 5.6 4.0 2.1 1.1 9.9 1.1 1.2 6.8 2.6 3.3 1.8 4.4 0.7 1.0 0.0 9.9 1.0 1.6 0.0 1.8 0.0 3.4 1.5 1.1 0.2 1.6 2.1 1.0 0.5 0.8 1.2 0.3 2.9 1.3 0.8 1.7 1.3 14.7 30.5 24.6 22.5 14.9 22.7 47.1 26.3 34.3 25.5 28.6 51.3 12.0 3.2 5.5 7.5 4.5 3.2 5.5 9.7 6.2 2.4 3.5 2.7 5.6 5.7 6.9 5.5 0.0 20.3 31.1 6.1 0.0 5.2 52.1 23.8 12.5 13.5 1.8 31.5 87.9 8.2 12.0 17.8 4.6 5.1 11.4 20.6 10.4 0.2 18.2 0.0 95.8 0.7 10.2 7.2 16.4 72.8 5.9 17.0 3.6 23.4 9.4 4.0 9.2 56.3 407.6 5.5 18.7 8.6 15.7 1.3 0.0 0.6 21.4 1.2 19.7 5.3 6.9 4.9 2.8 1.1 2.6 22.2 14.1 3.7 1.4 3.6 AGR3 "BCMP11, hAG-3, HAG3, PDIA18" ENSG00000173467 "Anterior gradient 3, protein disulphide isomerase family member" Q8TD06 7 16859412-16881987 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 225.2;intestine: 237.6;lung: 152.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 861.1;Intestinal goblet cells: 701.9;Paneth cells: 744.5;Proximal enterocytes: 1051.2;Respiratory ciliated cells: 1771.2;Undifferentiated cells: 495.4" "Cancer enhanced" "Detected in many" "breast cancer: 104.5" "Region enhanced" "Detected in some" "midbrain: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 28 "OE19: 109.8;T-47d: 339.3" "Region enriched" "Detected in some" 5 "olfactory bulb: 4.6" HPA053942 Enhanced Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" NA NA 67000 "Cluster 9: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Endoplasmic reticulum" Vesicles "HPA053942: AB_2682317" "unprognostic (2.18e-2)" "unprognostic (2.02e-1)" "unprognostic (2.13e-1)" "unprognostic (9.59e-2)" "unprognostic (3.32e-3)" "unprognostic (3.08e-2)" "unprognostic (1.49e-1)" "unprognostic (1.46e-1)" "unprognostic (7.29e-2)" "unprognostic (1.13e-1)" "unprognostic (8.56e-3)" "unprognostic (2.32e-1)" "unprognostic (2.96e-1)" "unprognostic (6.66e-2)" "unprognostic (1.57e-1)" 0.6 0.1 0.0 11.0 0.0 0.0 69.6 0.0 0.2 25.0 0.1 219.9 167.2 8.7 0.0 1.5 225.2 48.3 0.1 0.1 0.4 2.5 0.3 152.7 0.2 2.0 3.4 0.3 10.7 0.0 21.2 0.8 1.0 4.8 214.9 0.0 30.9 0.8 0.0 1.5 237.6 8.7 0.7 0.3 99.9 0.2 0.2 0.0 7.3 0.0 0.8 27.6 0.2 0.5 0.0 0.6 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.2 109.8 0.0 0.0 0.0 2.3 8.1 0.0 1.3 0.4 0.0 0.6 0.0 0.0 339.3 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 2.0 3.4 1.0 0.7 0.2 0.5 0.7 333.3 408.1 0.3 1.4 2.7 12.5 108.5 0.0 0.0 105.1 51.9 0.1 31.5 319.9 29.5 0.0 3.4 0.7 380.0 1.9 30.4 0.0 861.1 7.4 1.9 112.7 0.0 0.2 71.4 3.3 5.3 71.4 39.2 20.8 0.0 0.0 0.0 0.5 0.0 0.2 701.9 134.3 0.0 0.3 0.0 0.3 2.3 0.0 0.0 0.6 0.0 0.0 0.0 0.1 16.6 744.5 0.0 0.4 7.1 1051.2 0.0 1771.2 0.0 0.0 0.0 27.9 0.0 0.1 0.0 9.8 2.2 4.1 0.0 495.4 117.9 AGTPBP1 "CCP1, KIAA1035, Nna1" ENSG00000135049 "ATP/GTP binding protein 1" Q9UPW5 9 85546539-85742029 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 60.1;brain: 73.4;retina: 46.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 176.7;Inhibitory neurons: 163.0;Oligodendrocytes: 463.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057208, HPA071094" Approved Approved Nucleoli,Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoli, Vesicles" "HPA057208: AB_2683370, HPA071094: " "unprognostic (2.15e-1)" "unprognostic (3.78e-2)" "unprognostic (4.93e-3)" "unprognostic (6.12e-2)" "unprognostic (1.42e-1)" "unprognostic (8.95e-3)" "unprognostic (1.86e-2)" "unprognostic (1.65e-1)" "unprognostic (1.71e-1)" "unprognostic (8.26e-3)" "unprognostic (5.69e-3)" "unprognostic (6.31e-2)" "unprognostic (3.07e-2)" "unprognostic (1.11e-1)" "unprognostic (1.39e-1)" "unprognostic (9.60e-3)" "unprognostic (1.25e-1)" 8.4 5.5 31.1 9.5 44.3 60.1 6.2 23.2 36.3 4.7 0.0 5.1 3.7 4.9 3.9 5.3 4.6 5.3 12.2 20.1 30.3 6.9 4.6 14.4 9.4 30.5 28.6 3.6 6.7 7.5 5.3 6.1 31.5 4.7 5.8 46.5 4.1 3.0 16.5 6.2 5.1 6.5 32.0 14.8 5.5 14.1 34.3 12.4 5.8 20.5 8.4 5.7 4.3 73.4 5.1 9.6 27.9 11.1 5.6 6.0 10.6 7.4 6.4 7.4 8.4 5.2 8.6 31.3 6.2 7.7 13.2 2.9 13.0 9.4 6.9 33.6 11.8 5.3 11.5 9.3 11.8 24.5 6.2 5.8 10.8 7.0 23.5 4.8 11.9 15.9 6.7 24.5 3.3 8.0 19.3 14.5 19.3 18.1 6.8 17.3 10.2 9.8 12.8 5.4 33.5 23.7 8.4 9.1 15.4 26.1 3.5 7.8 12.0 4.8 8.5 30.4 8.9 16.7 14.8 14.3 10.1 23.5 9.8 37.4 14.4 12.7 9.0 8.4 8.8 2.3 4.4 7.0 15.6 1.7 3.7 7.0 21.2 6.8 6.7 2.5 5.1 9.6 31.1 44.3 23.2 36.3 20.1 30.3 30.5 28.6 31.5 32.0 34.3 73.4 22.3 64.1 12.8 46.0 14.3 7.9 2.6 2.9 8.0 38.0 4.7 4.8 48.3 0.0 13.8 3.7 102.2 4.1 41.8 4.3 7.9 5.7 52.5 29.3 8.6 12.0 7.7 16.8 176.7 4.0 4.3 6.9 9.2 22.0 27.1 9.2 8.2 3.7 8.1 35.3 163.0 5.6 6.1 35.4 24.1 53.9 1.8 42.8 3.6 61.8 46.6 16.7 47.4 82.9 463.5 5.1 1.2 2.6 26.2 3.8 3.2 9.8 14.7 59.1 13.1 9.3 10.4 46.6 29.2 9.2 10.7 2.9 26.3 6.4 4.7 2.3 AGTR1 "AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R" ENSG00000144891 "Angiotensin II receptor type 1" P30556 3 148697784-148743008 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 96.6;placenta: 141.6" "Cell type enhanced" "Detected in some" "Fibroblasts: 53.1;Hepatocytes: 30.9;Leydig cells: 145.1;Sertoli cells: 144.7;Smooth muscle cells: 71.2" "Group enriched" "Detected in many" 8 "breast cancer: 9.6;liver cancer: 9.8;prostate cancer: 6.8;renal cancer: 2.8" "Region enhanced" "Detected in some" "midbrain: 8.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 176.8;ASC TERT1: 24.4;BJ hTERT+ SV40 Large T+: 34.8;HBF TERT88: 53.9;HSkMC: 32.2" "Low region specificity" "Detected in all" HPA003596 Enhanced Uncertain Vesicles NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA003596: AB_1845163" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (8.78e-2)" "unprognostic (2.48e-4)" "unprognostic (5.28e-3)" "unprognostic (1.55e-1)" "unprognostic (3.46e-1)" "unprognostic (1.28e-2)" "unprognostic (3.26e-2)" "unprognostic (3.08e-2)" "unprognostic (9.25e-3)" "unprognostic (4.11e-2)" "unprognostic (4.79e-2)" "unprognostic (3.21e-3)" "unprognostic (1.46e-1)" "unprognostic (2.54e-1)" "unprognostic (5.41e-3)" 65.9 38.2 0.3 1.8 0.7 0.0 39.9 0.2 0.4 3.4 0.4 21.1 0.8 3.5 2.7 2.8 9.8 6.2 10.9 0.4 1.4 18.4 96.6 10.4 0.7 2.1 8.1 3.8 3.5 2.8 3.8 141.6 0.9 5.3 4.4 0.9 4.7 4.2 11.6 15.8 4.3 4.6 0.2 9.1 6.5 2.2 0.7 3.0 14.2 13.8 0.2 14.6 6.1 0.2 0.0 1.0 0.8 0.0 176.8 24.4 0.0 0.2 3.9 34.8 20.0 0.0 0.0 0.0 0.0 2.6 0.2 0.0 0.0 0.0 53.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 32.2 0.0 3.4 1.8 1.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.2 0.4 0.4 1.4 2.1 8.1 0.9 0.2 0.7 0.2 20.5 0.0 0.6 0.0 0.0 3.4 0.2 0.0 0.0 0.0 1.3 0.9 6.3 2.8 0.0 0.0 0.0 0.5 0.3 0.1 0.0 0.1 0.8 0.0 0.3 3.8 23.5 0.0 0.1 7.6 0.3 53.1 0.5 0.0 0.0 0.0 17.5 30.9 0.7 0.0 0.0 0.2 0.0 0.3 3.5 1.7 145.1 0.5 1.8 2.8 0.0 5.7 0.0 0.0 0.1 0.5 0.0 7.5 0.4 1.1 0.0 0.1 0.0 0.1 144.7 7.6 71.2 0.0 1.8 0.3 1.7 0.3 0.5 0.3 0.0 0.1 AGTRAP ATRAP ENSG00000177674 "Angiotensin II receptor associated protein" Q6RW13 1 11736084-11754802 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 446.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-937: 196.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044120 Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" Vesicles "Golgi apparatus" "HPA044120: AB_10960748" "unprognostic (1.08e-3)" "unprognostic (2.98e-3)" "unprognostic (6.10e-2)" "unprognostic (1.59e-1)" "unprognostic (1.69e-1)" "unprognostic (7.92e-3)" "prognostic unfavorable (6.57e-7)" "unprognostic (4.44e-2)" "unprognostic (7.96e-2)" "unprognostic (4.31e-2)" "unprognostic (1.61e-2)" "unprognostic (7.22e-2)" "unprognostic (1.61e-2)" "unprognostic (1.27e-1)" "unprognostic (1.44e-1)" "unprognostic (2.33e-3)" "unprognostic (5.89e-2)" 44.1 50.3 26.6 30.2 28.5 132.3 44.3 27.1 32.4 34.6 44.0 29.3 11.2 24.7 47.7 53.6 48.3 25.2 37.0 24.5 30.5 65.8 29.5 62.3 23.4 37.3 28.8 26.9 67.3 25.7 31.2 22.0 31.3 79.1 9.3 3.4 39.0 21.0 54.3 38.8 25.7 20.3 28.4 83.4 33.7 24.7 31.8 11.3 40.8 12.4 13.3 43.9 43.3 31.1 55.9 66.7 16.7 36.9 27.5 34.9 30.5 28.6 49.0 34.8 30.2 42.0 129.7 5.4 126.7 35.4 87.3 45.8 27.9 135.3 10.7 3.1 61.5 1.6 38.4 51.8 84.9 27.6 64.3 34.6 105.4 112.9 59.2 42.4 46.9 17.3 73.8 52.8 19.8 44.6 13.7 80.9 29.7 24.0 67.3 4.6 15.0 27.5 56.7 5.2 14.6 22.0 52.5 26.4 48.4 22.3 59.8 57.4 26.0 44.1 30.8 70.3 30.9 19.6 24.2 33.3 111.7 196.1 20.7 483.4 844.2 694.6 185.7 442.7 90.4 47.0 66.9 109.8 312.2 38.2 72.0 93.5 756.8 73.0 385.2 25.5 90.8 577.4 26.6 28.5 27.1 32.4 24.5 30.5 37.3 28.8 31.3 28.4 31.8 31.1 46.2 22.4 27.4 3.9 12.1 11.6 30.7 112.4 16.5 1.0 54.8 56.0 12.0 32.9 41.6 36.8 6.2 15.7 60.1 6.9 9.8 95.5 20.6 75.3 30.8 36.1 7.2 21.0 0.2 446.7 92.4 45.3 11.2 41.1 88.0 19.1 42.1 7.7 118.3 3.3 0.2 12.3 20.3 143.5 18.9 23.4 37.9 97.8 28.4 1.9 107.4 19.4 122.6 0.5 7.0 96.9 22.5 27.1 8.6 66.5 8.6 55.3 78.5 5.6 13.1 13.0 23.8 3.5 36.1 34.4 13.5 13.1 45.0 50.4 18.2 25.2 AGXT "AGT, AGT1, AGXT1, PH1, SPAT, SPT" ENSG00000172482 "Alanine--glyoxylate and serine--pyruvate aminotransferase" P21549 2 240868824-240880502 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 315 "liver: 2199.2" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 2037.9" "Cancer enriched" "Detected in some" 425 "liver cancer: 253.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Hep G2: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035370, HPA035371" Enhanced Supported Vesicles NA NA 4700000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA035370: AB_10673218, HPA035371: AB_2674593" "unprognostic (3.14e-2)" "unprognostic (2.58e-1)" "unprognostic (3.37e-4)" "unprognostic (1.04e-1)" "unprognostic (1.23e-2)" "unprognostic (9.56e-2)" "prognostic favorable (5.92e-5)" "unprognostic (8.28e-2)" "unprognostic (2.77e-1)" "unprognostic (5.39e-2)" "unprognostic (1.55e-1)" "unprognostic (7.57e-3)" "unprognostic (2.54e-1)" "unprognostic (9.22e-2)" "unprognostic (1.37e-1)" "unprognostic (3.26e-2)" 0.5 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 6.9 2199.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 2.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 5.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.3 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 44.3 0.1 7.3 0.0 0.7 0.0 7.6 23.5 0.1 0.1 0.2 0.0 2.8 9.0 128.4 0.0 1.7 26.7 0.4 0.0 0.4 0.0 0.0 52.5 2037.9 0.2 0.0 0.0 8.1 4.1 53.5 0.0 1.6 0.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 12.8 0.4 0.0 0.8 1.9 343.9 0.1 0.0 0.0 2.7 0.1 0.1 0.0 0.0 0.0 1.9 5.2 0.1 1.5 0.4 AIFM2 "AMID, FLJ14497, PRG3" ENSG00000042286 "Apoptosis inducing factor mitochondria associated 2" Q9BRQ8 10 70098223-70132934 "Predicted intracellular proteins" "DNA-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 173.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028961, HPA042309, HPA075576" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Plasma membrane, Cytosol" "HPA028961: AB_2672844, HPA042309: AB_10796575, HPA075576: " "unprognostic (6.62e-2)" "unprognostic (2.73e-1)" "unprognostic (4.29e-1)" "prognostic favorable (2.80e-4)" "unprognostic (7.26e-3)" "unprognostic (2.57e-2)" "unprognostic (7.95e-3)" "unprognostic (2.80e-1)" "unprognostic (5.31e-2)" "unprognostic (8.90e-2)" "unprognostic (2.23e-1)" "unprognostic (1.53e-1)" "unprognostic (4.49e-1)" "unprognostic (4.59e-3)" "unprognostic (2.17e-1)" "unprognostic (1.11e-1)" "prognostic favorable (2.92e-4)" 39.6 13.5 7.5 6.3 8.1 1.9 31.2 7.3 8.0 6.9 8.6 12.9 9.3 7.8 9.0 13.3 6.8 5.0 17.0 6.9 7.7 10.4 21.9 9.3 5.1 8.2 7.3 7.9 5.0 3.2 5.6 4.1 6.9 9.9 7.1 2.4 7.6 7.7 9.8 5.6 11.5 5.0 6.2 7.7 9.9 3.9 8.3 2.4 14.6 7.3 3.6 12.0 6.3 6.5 26.5 45.2 1.1 11.3 26.2 9.8 0.3 10.4 25.5 21.0 23.6 35.3 49.8 3.8 25.8 14.5 27.5 27.9 12.7 3.8 5.9 50.8 1.9 0.2 27.3 173.3 56.1 0.3 6.4 13.3 8.4 33.8 7.2 13.2 9.5 1.7 20.5 21.9 11.0 33.5 1.2 1.3 4.5 21.2 14.6 0.8 4.2 12.4 11.4 19.2 3.6 0.8 19.1 16.6 29.8 1.8 0.7 7.2 12.0 0.5 25.3 15.6 30.8 16.2 32.7 7.3 14.0 0.9 13.9 1.0 0.5 0.5 1.8 0.5 1.5 1.7 0.6 1.5 0.4 1.5 0.8 1.3 0.5 4.0 0.5 0.2 1.3 0.7 7.5 8.1 7.3 8.0 6.9 7.7 8.2 7.3 6.9 6.2 8.3 6.5 11.6 6.4 14.1 7.2 5.0 2.3 15.0 8.4 2.8 5.7 5.5 4.7 13.8 8.6 10.5 18.4 0.0 13.9 1.4 53.1 3.9 40.7 24.1 6.0 7.7 4.8 12.0 7.0 8.2 21.9 3.0 11.2 14.3 6.2 11.4 22.3 1.8 25.0 10.2 1.7 5.2 7.1 14.2 3.3 3.3 47.0 5.3 6.7 8.8 4.7 34.4 4.8 1.0 5.5 3.5 40.8 22.7 4.5 17.0 14.6 28.7 22.6 9.5 2.1 19.7 11.8 12.8 6.2 3.9 5.1 1.4 18.6 3.8 8.8 13.7 20.4 AKAP7 "AKAP15, AKAP18" ENSG00000118507 "A-kinase anchoring protein 7" "O43687, Q9P0M2" 6 131135467-131283535 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 56.6" "Cell type enhanced" "Detected in many" "Astrocytes: 88.8;Cholangiocytes: 177.3;Oligodendrocyte precursor cells: 123.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NTERA-2: 27.2;RPTEC TERT1: 23.5;RT4: 27.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027172, HPA027200, HPA028327" Approved Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" Vesicles "HPA027172: AB_1844689, HPA027200: , HPA028327: AB_10601353" "unprognostic (2.83e-2)" "unprognostic (2.70e-1)" "unprognostic (2.88e-2)" "unprognostic (1.45e-3)" "unprognostic (4.57e-2)" "unprognostic (1.24e-1)" "unprognostic (1.93e-1)" "unprognostic (2.70e-2)" "unprognostic (4.41e-1)" "unprognostic (1.18e-1)" "unprognostic (3.89e-1)" "unprognostic (1.54e-1)" "unprognostic (1.32e-3)" "unprognostic (2.52e-1)" "unprognostic (6.03e-3)" "unprognostic (2.53e-1)" "prognostic favorable (2.56e-4)" 9.0 56.6 15.8 6.4 16.3 10.9 6.7 17.7 20.7 8.1 11.5 19.1 29.8 6.4 5.7 4.2 6.8 9.9 6.7 16.0 16.7 8.1 24.4 6.6 11.2 15.3 16.2 9.8 42.0 4.0 4.3 4.0 15.3 14.0 18.9 7.6 4.6 6.4 15.9 2.8 16.5 5.9 16.7 9.6 5.3 8.8 17.0 11.9 5.9 14.4 7.6 8.7 5.6 15.8 1.2 2.1 7.8 3.8 4.4 9.0 5.4 3.3 5.3 5.5 7.3 2.8 2.2 0.1 6.1 5.7 4.1 0.1 2.3 3.6 4.0 0.0 3.3 8.0 2.7 12.2 6.1 0.4 2.5 7.8 2.4 3.6 4.6 5.1 5.8 4.6 1.4 11.7 5.3 2.1 3.6 2.1 27.2 0.8 2.9 7.3 5.1 0.1 23.5 27.2 0.1 2.7 4.5 0.4 11.1 4.5 1.8 17.1 2.1 2.5 3.5 7.5 8.3 10.5 0.1 2.0 6.3 8.1 5.9 15.2 1.9 0.3 8.1 3.8 12.8 3.7 11.1 11.0 2.4 5.5 17.6 11.0 0.5 4.4 4.7 0.1 4.3 6.0 15.8 16.3 17.7 20.7 16.0 16.7 15.3 16.2 15.3 16.7 17.0 15.8 11.7 19.2 9.1 88.8 16.4 6.2 6.5 0.8 6.8 22.3 10.1 13.2 10.4 177.3 1.6 5.5 16.7 8.2 18.0 22.1 19.6 35.7 8.2 31.6 13.4 6.5 1.2 63.8 44.7 4.2 10.2 7.4 6.1 35.6 10.8 22.9 9.7 39.9 8.6 8.4 79.1 14.8 10.2 20.8 9.9 2.7 8.4 12.9 1.8 68.4 9.8 38.2 25.7 123.6 62.7 2.2 33.2 5.7 3.4 8.2 13.6 26.5 1.4 13.2 0.0 12.6 6.9 4.6 10.0 7.0 4.1 4.7 23.9 26.0 22.0 4.9 AKAP9 "AKAP350, AKAP450, CG-NAP, HYPERION, KIAA0803, LQT11, MU-RMS-40.16A, PPP1R45, PRKA9, YOTIAO" ENSG00000127914 "A-kinase anchoring protein 9" Q99996 7 91940840-92110673 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 2230.9;Rod photoreceptor cells: 1279.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008548, CAB012909, HPA026109" Supported Enhanced "Golgi apparatus,Vesicles,Centrosome" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 54: Non-specific - Microtubule organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus" "Vesicles, Centrosome" "CAB012909: AB_2533235, HPA008548: AB_1078121, HPA026109: AB_1844688" "unprognostic (9.57e-2)" "unprognostic (1.66e-1)" "unprognostic (2.13e-1)" "unprognostic (5.97e-3)" "unprognostic (1.20e-1)" "unprognostic (1.47e-1)" "unprognostic (4.75e-2)" "unprognostic (1.31e-2)" "unprognostic (1.28e-1)" "unprognostic (6.59e-2)" "unprognostic (7.59e-2)" "unprognostic (6.32e-2)" "prognostic favorable (2.10e-6)" "unprognostic (8.89e-2)" "unprognostic (1.73e-1)" "unprognostic (7.77e-2)" "unprognostic (3.96e-2)" 7.1 8.3 8.6 6.2 9.0 8.6 11.0 15.3 14.1 6.5 15.5 16.0 16.5 6.4 3.9 7.9 8.4 10.4 6.5 8.6 11.0 13.2 16.2 7.8 5.8 8.8 9.6 11.9 9.5 12.7 8.6 5.4 9.0 7.5 14.6 31.4 9.6 3.8 16.2 6.8 18.6 4.0 7.7 5.0 9.4 4.1 11.9 9.3 9.3 10.0 5.3 5.5 7.2 9.7 11.7 8.1 9.6 5.8 11.6 11.3 6.2 8.7 6.3 4.9 5.9 10.3 8.0 9.2 12.5 7.3 7.5 8.3 10.5 5.6 9.2 9.8 8.2 10.9 11.6 7.3 4.0 18.5 9.6 6.2 6.2 9.1 8.8 7.7 10.3 10.6 19.3 13.0 7.4 14.1 10.4 7.0 8.3 6.5 8.4 7.6 18.2 6.2 4.9 11.5 13.3 11.0 19.0 16.9 10.1 11.1 5.1 9.8 17.5 9.5 11.2 14.5 12.6 7.3 13.0 13.6 6.2 7.8 9.4 1.1 0.6 0.9 1.3 0.6 0.9 1.9 1.1 1.1 0.4 1.6 1.2 1.0 0.7 1.2 0.6 3.2 1.0 0.2 8.6 9.0 15.3 14.1 8.6 11.0 8.8 9.6 9.0 7.7 11.9 9.7 123.3 525.6 357.0 141.3 143.3 103.5 126.5 112.6 170.8 273.5 165.4 150.9 253.2 297.4 208.4 176.6 2230.9 141.4 201.5 293.4 101.8 131.0 22.5 392.3 157.7 115.9 185.1 129.4 142.6 92.6 81.9 123.5 152.9 185.0 136.6 386.1 98.2 153.5 57.2 360.1 182.6 350.8 136.3 78.3 88.4 17.5 173.4 101.6 58.7 115.2 121.5 155.7 119.4 169.9 187.1 102.4 218.9 135.8 193.5 91.4 298.5 47.2 506.3 1279.6 138.1 206.1 116.1 83.0 129.0 87.3 111.8 333.8 145.7 135.8 171.4 97.6 AKT2 PKBβ ENSG00000105221 "AKT serine/threonine kinase 2" P31751 19 40230317-40285536 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Diabetes mellitus, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004204, HPA064521" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Vesicles, Cytosol" "CAB004204: AB_626659, HPA064521: AB_2685278" "unprognostic (6.13e-2)" "unprognostic (2.21e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.05e-6)" "unprognostic (2.85e-1)" "unprognostic (6.40e-3)" "unprognostic (9.59e-2)" "unprognostic (1.22e-2)" "unprognostic (2.98e-2)" "unprognostic (2.49e-2)" "unprognostic (3.02e-1)" "prognostic unfavorable (4.74e-4)" "unprognostic (1.30e-2)" "unprognostic (1.89e-1)" "unprognostic (3.28e-1)" "unprognostic (6.16e-2)" "unprognostic (2.00e-1)" 62.8 40.0 31.7 37.3 31.3 48.4 38.6 58.3 40.0 49.8 55.1 42.3 24.5 43.5 49.4 42.5 46.1 25.1 40.8 31.5 24.5 52.2 59.2 30.7 38.1 32.0 26.0 53.9 41.9 58.5 47.8 27.6 26.3 41.2 23.3 41.2 32.5 45.0 101.3 39.4 35.6 34.2 22.1 38.1 33.1 29.7 28.0 53.4 100.1 118.7 37.0 39.8 41.5 35.2 66.2 160.1 63.1 61.5 72.0 88.9 32.5 41.7 63.5 87.6 77.9 71.8 60.8 67.4 36.8 96.3 37.2 28.2 66.8 90.0 56.1 62.5 74.3 43.4 116.5 44.7 45.8 50.7 50.5 82.7 53.6 58.6 56.4 71.9 19.0 73.0 57.3 67.5 49.8 54.6 81.1 24.7 31.7 73.7 41.5 54.2 32.1 48.5 68.3 105.7 82.7 49.8 43.3 75.0 35.0 62.5 59.8 64.9 18.8 52.7 51.5 47.3 67.6 61.5 59.0 56.4 52.6 59.7 44.3 5.7 2.6 2.1 2.2 1.2 2.2 1.9 1.8 1.5 1.7 2.9 1.7 2.6 4.0 1.7 1.6 4.9 1.6 1.7 31.7 31.3 58.3 40.0 31.5 24.5 32.0 26.0 26.3 22.1 28.0 35.2 18.1 16.0 15.9 51.2 33.0 23.8 23.9 20.9 26.2 67.6 25.3 23.9 31.2 30.0 18.1 60.7 41.7 31.3 26.0 23.7 21.5 19.7 5.5 26.2 26.7 17.4 19.2 19.1 30.4 30.4 25.2 27.9 20.9 25.8 14.0 44.2 13.9 87.5 22.3 60.6 25.3 20.1 22.4 23.2 17.5 10.5 42.9 20.0 23.2 23.4 21.7 46.2 50.4 41.7 40.6 24.8 16.9 26.7 30.4 29.7 21.8 24.8 24.9 97.4 19.7 29.3 25.0 14.8 15.6 31.1 27.4 38.7 23.1 56.9 23.3 29.4 AL049629.2 ENSG00000284969 "Novel protein" 11 33698261-33722467 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Ductal cells: 9.1;Exocrine glandular cells: 14.4;Pancreatic endocrine cells: 44.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 42.8;HUVEC TERT2: 55.1;TIME: 66.2;U-2197: 57.6" HPA026494 Uncertain Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Golgi apparatus, Vesicles" "HPA026494: AB_1846321" 2.5 0.7 1.5 2.3 1.4 1.5 1.1 1.5 1.6 0.5 2.5 0.7 1.4 1.3 1.8 1.2 0.6 2.1 1.1 1.4 1.7 1.6 0.8 1.7 0.3 1.8 2.0 0.6 0.7 1.0 1.5 1.8 0.5 0.7 0.6 2.4 0.7 3.5 0.3 0.3 0.6 1.8 0.5 2.9 1.1 1.8 0.2 0.8 1.1 1.4 2.3 2.1 1.3 3.3 0.2 2.4 3.4 7.9 0.1 18.5 8.4 2.3 2.2 0.1 9.6 0.0 2.3 12.5 1.1 2.2 0.3 42.8 4.0 2.0 0.4 0.3 7.1 0.8 0.8 0.4 1.2 3.0 2.7 1.0 14.7 1.9 55.1 0.3 0.5 7.4 15.4 1.0 1.8 0.8 0.5 1.3 24.8 0.4 1.5 1.3 4.9 2.2 0.0 0.3 2.0 3.4 7.3 0.2 1.0 0.0 66.2 7.0 2.7 57.6 7.4 3.8 3.7 0.3 16.0 0.0 17.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.5 1.4 1.5 1.6 1.4 1.7 1.8 2.0 1.8 1.8 1.8 2.1 0.5 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.7 0.2 2.1 0.0 0.0 0.0 14.4 0.0 0.2 0.0 1.3 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.8 0.0 0.0 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 AL162231.1 ENSG00000187186 "Uncharacterized LOC730098" 9 34664163-34666112 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 292.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 24.5;Breast myoepithelial cells: 36.4;Collecting duct cells: 36.8;Distal tubular cells: 25.4;Proximal tubular cells: 37.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 18.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 51.4" HPA069617 Enhanced Approved "Nucleoli,Endoplasmic reticulum,Vesicles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 7: Non-specific - Mitochondria" Vesicles "Nucleoli, Endoplasmic reticulum" "HPA069617: AB_2686161" "unprognostic (8.20e-3)" "unprognostic (3.13e-1)" "unprognostic (1.17e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (6.63e-5)" "unprognostic (2.30e-1)" "unprognostic (2.46e-2)" "unprognostic (9.22e-2)" "unprognostic (2.11e-1)" "unprognostic (2.55e-2)" "unprognostic (5.99e-4)" "unprognostic (8.02e-2)" "unprognostic (1.39e-5)" "unprognostic (1.03e-1)" "unprognostic (1.07e-1)" "unprognostic (7.08e-3)" "unprognostic (2.00e-2)" 6.0 9.8 49.0 2.9 53.7 2.6 7.8 48.5 76.1 9.3 42.3 9.9 3.9 10.4 19.4 2.4 8.3 2.8 27.8 49.4 50.0 14.6 6.7 5.1 1.9 48.4 46.8 14.0 8.8 6.4 60.6 3.1 48.6 11.7 1.4 6.5 7.3 2.5 36.7 4.6 4.3 2.4 47.8 2.6 6.3 292.4 52.6 2.1 13.6 22.2 0.7 8.0 5.9 49.8 0.6 10.1 9.1 11.9 7.4 3.6 8.2 8.0 2.4 4.9 5.7 1.7 4.0 0.0 1.0 5.4 9.8 2.5 5.9 2.8 0.9 22.1 1.1 0.0 51.4 3.0 1.8 4.5 7.4 3.9 3.1 3.0 3.0 6.8 1.4 12.3 5.5 12.3 3.7 0.0 1.0 4.5 7.7 9.1 2.6 0.0 8.7 1.6 9.3 0.0 9.4 15.2 5.5 1.8 14.0 5.1 4.6 12.5 1.8 17.3 24.0 5.5 1.9 13.1 4.7 1.9 21.4 2.5 24.3 18.2 2.4 2.6 1.8 1.4 1.6 4.4 2.1 0.9 0.8 1.3 2.6 1.3 3.4 4.1 0.8 11.7 2.1 1.3 49.0 53.7 48.5 76.1 49.4 50.0 48.4 46.8 48.6 47.8 52.6 49.8 1.6 9.6 7.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 24.5 36.4 0.0 0.0 2.5 36.8 0.0 13.7 0.4 0.0 25.4 16.2 0.0 7.3 10.4 0.7 0.0 0.0 0.0 10.7 12.1 6.6 0.0 6.0 2.5 5.4 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 5.2 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 0.0 37.1 3.6 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 7.1 1.0 4.0 0.0 0.0 AL592490.1 ENSG00000197991 "Novel protein" 13 61409858-61427849 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Group enriched" "Detected in some" 25 "Alveolar cells type 1: 3.2;Alveolar cells type 2: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062669 Approved "Vesicles,Cytokinetic bridge" Yes NA "Cluster 11: Alveolar cells - Smell perception" Vesicles "Cytokinetic bridge" "HPA062669: AB_2732687" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL645922.1 ENSG00000244255 "Novel complement component 2 (C2) and complement factor B (CFB) protein" 6 31927698-31952048 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "liver: 2.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.5;Club cells: 3.1;Fibroblasts: 1.2;Respiratory ciliated cells: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000951, HPA001817, HPA001832" Approved Approved "Endoplasmic reticulum,Vesicles,Cell Junctions" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 49: Ciliated cells - Cilium organization" "Endoplasmic reticulum, Vesicles" "Cell Junctions" "HPA000951: AB_2797216, HPA001817: AB_1078779, HPA001832: AB_1078778" "unprognostic (7.68e-2)" "unprognostic (1.86e-2)" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALCAM "CD166, MEMD" ENSG00000170017 "Activated leukocyte cell adhesion molecule" Q13740 3 105366909-105576900 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Cell adhesion, Immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 438.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 737.2;Oligodendrocyte precursor cells: 680.1;Oligodendrocytes: 981.1;Respiratory ciliated cells: 318.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 29.6" "Lineage enriched" "Detected in many" 6 "dendritic cells: 29.6" "Cell line enhanced" "Detected in many" "hTERT-HME1: 393.4;U-138 MG: 473.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002148, HPA010926" Enhanced Uncertain Vesicles "Secreted to blood" NA NA 1600000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "CAB002148: AB_442053, HPA010926: AB_1078449" "unprognostic (6.82e-2)" "unprognostic (2.66e-1)" "unprognostic (2.13e-1)" "unprognostic (2.19e-1)" "unprognostic (9.48e-3)" "unprognostic (2.08e-2)" "unprognostic (1.63e-3)" "unprognostic (3.89e-2)" "unprognostic (1.75e-1)" "unprognostic (4.01e-2)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "prognostic favorable (3.15e-4)" "unprognostic (3.15e-1)" "unprognostic (4.47e-2)" "unprognostic (9.57e-2)" "unprognostic (7.76e-2)" 7.7 32.7 31.3 12.2 48.1 10.5 81.0 42.4 47.2 28.0 14.4 16.6 17.0 15.5 35.4 8.2 49.1 23.3 9.6 32.4 70.6 22.2 47.9 74.1 9.9 50.7 54.9 57.6 32.7 438.9 19.2 12.1 51.7 32.7 14.5 3.6 33.8 39.6 0.8 11.0 17.4 16.2 44.9 6.3 33.4 4.5 45.7 14.2 62.4 5.0 14.5 25.6 6.4 85.0 248.4 93.7 65.9 33.7 97.6 42.7 0.6 197.7 115.1 124.9 173.8 0.8 50.5 17.3 80.3 280.6 68.8 186.5 10.6 157.4 366.1 16.6 16.6 2.4 65.8 4.6 109.6 101.3 0.8 76.0 114.9 159.9 393.4 346.8 139.3 17.9 0.3 28.6 165.9 16.9 14.5 37.0 13.7 79.3 104.8 9.4 5.9 1.0 188.9 27.2 47.5 131.9 20.6 19.6 12.9 25.9 37.7 66.3 291.6 473.7 162.3 20.9 237.2 0.3 0.6 1.8 108.0 21.1 207.4 0.0 4.7 3.5 0.6 2.1 1.9 4.7 1.5 0.9 29.6 3.0 0.3 0.2 5.3 0.6 1.2 10.5 2.4 3.2 31.3 48.1 42.4 47.2 32.4 70.6 50.7 54.9 51.7 44.9 45.7 85.0 4.5 737.2 143.6 238.6 17.9 12.1 22.8 65.8 12.0 3.0 112.4 47.9 10.1 62.9 255.3 16.5 2.1 0.7 19.5 9.1 1.9 18.5 66.5 108.6 20.1 11.9 16.8 6.3 143.0 43.0 0.7 37.0 23.4 158.1 11.4 29.5 3.6 44.1 57.5 1.7 287.0 16.3 46.8 51.0 162.6 60.1 3.7 86.4 24.9 40.3 93.4 1.3 1.0 680.1 981.1 55.2 8.5 6.4 21.8 117.5 9.6 24.2 318.3 0.8 0.0 7.9 21.8 8.1 5.5 30.1 20.2 0.8 8.9 22.8 10.4 105.4 ALDH3A1 ALDH3 ENSG00000108602 "Aldehyde dehydrogenase 3 family member A1" P30838 17 19737984-19748943 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 496.1;salivary gland: 128.0;stomach 1: 224.8" "Group enriched" "Detected in many" 4 "Basal respiratory cells: 389.5;Basal squamous epithelial cells: 274.3;Club cells: 150.1;Gastric mucus-secreting cells: 437.9;Respiratory ciliated cells: 412.7;Squamous epithelial cells: 342.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.4;lung cancer: 60.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "A549: 5094.7;OE19: 6071.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB045957, HPA051150, HPA063783" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 52000 "Cluster 22: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB045957: AB_11127164, HPA051150: AB_2681364, HPA063783: AB_2685122" "unprognostic (3.11e-5)" "unprognostic (1.20e-2)" "unprognostic (1.08e-1)" "unprognostic (7.04e-3)" "unprognostic (4.36e-3)" "prognostic favorable (7.55e-5)" "unprognostic (3.12e-1)" "unprognostic (3.84e-1)" "unprognostic (2.10e-1)" "unprognostic (1.67e-1)" "unprognostic (2.69e-3)" "unprognostic (5.54e-2)" "unprognostic (1.72e-1)" "unprognostic (3.84e-2)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (7.23e-2)" 1.7 1.0 0.4 1.3 0.7 0.1 3.2 0.3 0.4 6.7 17.5 4.5 6.2 0.3 0.2 496.1 5.5 10.3 0.3 1.0 0.4 1.3 1.9 10.9 0.5 0.6 2.1 0.4 0.5 0.0 0.9 0.0 0.5 1.9 3.3 0.1 128.0 1.5 1.3 72.6 3.5 0.4 0.9 0.9 224.8 1.6 1.3 0.6 0.5 0.3 33.7 6.2 22.3 0.9 0.1 5094.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 10.7 246.5 0.0 2.7 0.5 2.0 29.3 0.7 12.8 0.0 0.0 0.8 0.1 116.6 1.0 0.3 0.1 0.5 0.0 14.9 0.5 0.4 0.2 0.5 0.0 0.0 0.0 0.0 9.7 0.1 0.3 0.4 6071.6 19.8 0.0 0.0 0.0 0.0 87.0 0.2 0.6 24.8 0.0 0.0 0.2 0.2 0.9 0.6 0.3 0.8 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.7 0.3 0.4 1.0 0.4 0.6 2.1 0.5 0.9 1.3 0.9 0.7 3.2 5.5 0.0 0.7 44.1 46.8 389.5 274.3 0.0 0.1 1.5 0.4 2.8 150.1 0.0 0.0 0.0 0.0 5.1 0.0 1.4 1.5 12.4 0.2 1.3 1.8 0.0 0.1 0.5 0.0 1.6 437.9 0.8 2.5 0.3 1.4 3.2 0.2 0.0 0.0 4.8 83.4 0.3 1.8 5.2 0.9 1.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 9.5 4.7 1.9 3.2 5.8 3.4 5.0 412.7 0.2 0.0 1.7 20.1 1.7 8.6 342.2 32.0 0.0 0.5 0.2 8.4 64.3 ALDOC ENSG00000109107 "Aldolase, fructose-bisphosphate C" P09972 17 28573115-28576948 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1384.6;choroid plexus: 589.6;retina: 1183.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 112.5;Horizontal cells: 274.2;Muller glia cells: 127.1;Proximal enterocytes: 120.0;Rod photoreceptor cells: 348.5" "Cancer enriched" "Detected in all" 6 "glioma: 128.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 250.9;U-266/70: 161.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003282, CAB020828, HPA067442" Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" Yes No 150000000 "Cluster 20: T-cells - T-cell receptor" "Cluster 77: Retina - Visual perception" "Cluster 25: RPMI-8226 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Nucleoli fibrillar center" "Vesicles, Cytosol" "CAB020828: , HPA003282: AB_1078130, HPA067442: " "unprognostic (2.90e-1)" "unprognostic (4.45e-3)" "unprognostic (5.69e-3)" "unprognostic (1.43e-1)" "unprognostic (3.56e-1)" "prognostic unfavorable (9.80e-4)" "unprognostic (1.03e-1)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" "unprognostic (6.03e-3)" "unprognostic (3.90e-1)" "unprognostic (3.24e-2)" "prognostic unfavorable (1.29e-7)" "unprognostic (1.28e-1)" "unprognostic (2.00e-1)" "unprognostic (2.74e-2)" "unprognostic (1.23e-1)" 87.0 24.3 953.6 12.7 909.7 23.6 42.5 1238.3 1162.3 39.3 589.6 18.5 18.7 17.9 10.9 40.8 14.3 10.9 285.5 955.7 958.0 16.8 98.3 13.7 19.3 1297.5 962.6 39.1 4.9 12.1 30.6 4.1 1384.6 18.9 14.7 1183.1 19.9 15.8 4.8 74.5 43.9 12.4 926.9 24.4 23.3 14.2 1090.2 9.6 7.4 8.1 30.5 19.0 47.0 886.1 29.9 2.1 13.7 55.7 29.9 32.9 2.9 16.7 37.7 12.9 76.0 17.9 3.0 14.9 17.3 15.5 3.3 36.9 10.3 102.3 23.4 12.4 8.9 28.3 11.6 30.4 25.8 10.0 29.2 27.8 13.9 1.5 24.0 1.7 5.3 29.7 19.3 71.9 10.7 15.1 11.9 32.0 20.8 6.7 15.3 9.5 1.6 250.9 1.9 4.3 36.2 61.9 9.1 67.3 0.5 20.8 36.6 21.2 3.5 1.2 5.3 2.1 2.4 161.0 51.4 10.9 105.2 28.0 1.9 0.5 7.4 3.0 21.6 8.7 30.6 24.0 29.5 17.8 9.4 25.1 37.7 28.4 18.0 29.4 5.3 4.6 40.9 19.0 953.6 909.7 1238.3 1162.3 955.7 958.0 1297.5 962.6 1384.6 926.9 1090.2 886.1 4.2 0.0 15.8 97.6 9.8 7.5 20.3 80.5 8.6 112.5 9.0 11.0 22.1 11.5 29.3 7.3 106.3 1.1 9.5 31.7 3.9 21.9 0.9 1.0 3.0 11.3 21.6 3.2 19.2 10.2 6.5 5.8 6.6 1.2 13.3 4.9 14.3 93.1 5.4 274.2 41.3 12.9 28.5 4.4 5.3 1.3 9.3 3.1 24.9 21.5 34.1 127.1 12.3 26.7 16.8 12.4 12.4 10.1 2.6 6.1 120.0 2.1 11.8 348.5 13.1 6.4 10.1 0.3 3.2 7.9 10.9 1.5 17.0 11.7 5.1 7.8 ALG13 "CDG1S, CXorf45, FLJ23018, GLT28D1, MDS031, TDRD13, YGL047W" ENSG00000101901 "ALG13 UDP-N-acetylglucosaminyltransferase subunit" Q9NP73 X 111665811-111760649 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Glycosyltransferase, Hydrolase, Multifunctional enzyme, Protease, Thiol protease, Transferase" "Congenital disorder of glycosylation, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002853, HPA005498" Approved Approved Vesicles,Cytosol NA NA 11000000 "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Vesicles Cytosol "HPA002853: AB_1078131, HPA005498: " "unprognostic (4.13e-1)" "unprognostic (1.80e-1)" "unprognostic (2.45e-2)" "unprognostic (1.51e-1)" "unprognostic (6.97e-2)" "unprognostic (6.14e-2)" "unprognostic (2.74e-1)" "unprognostic (6.55e-3)" "unprognostic (2.26e-2)" "unprognostic (3.39e-3)" "unprognostic (1.73e-2)" "unprognostic (4.62e-3)" "prognostic unfavorable (1.10e-6)" "unprognostic (1.19e-1)" "unprognostic (1.29e-2)" "unprognostic (9.70e-2)" "unprognostic (2.45e-2)" 15.1 17.9 10.5 18.8 11.7 16.6 18.3 11.5 19.0 17.2 12.3 18.2 13.7 16.1 20.5 14.7 15.4 16.4 13.2 10.2 13.8 21.0 23.8 13.8 23.4 12.6 12.1 15.8 14.7 23.4 17.9 14.1 13.3 17.7 19.4 11.8 15.6 13.4 9.2 19.4 17.3 17.5 11.4 18.5 15.5 17.4 11.8 17.3 18.2 9.9 20.1 21.3 14.7 16.6 22.3 24.4 21.8 13.8 13.8 19.6 12.3 17.7 18.3 22.4 27.5 24.9 23.1 19.5 33.0 24.7 46.5 12.6 26.1 12.5 23.5 14.4 17.6 10.7 26.1 28.4 20.3 19.5 40.5 23.6 22.8 18.0 38.6 23.3 24.8 21.8 23.9 53.5 22.5 55.8 16.4 17.6 19.9 66.3 33.6 12.8 13.9 26.7 36.6 34.0 13.1 19.1 25.2 15.2 16.3 21.7 13.6 18.5 16.7 19.2 9.7 24.9 34.4 25.8 47.1 31.5 20.5 25.5 15.2 39.5 15.8 16.6 9.5 16.3 9.3 10.6 10.6 9.2 18.5 12.1 13.0 10.8 3.0 4.6 12.9 9.5 14.6 9.6 10.5 11.7 11.5 19.0 10.2 13.8 12.6 12.1 13.3 11.4 11.8 16.6 50.9 16.0 30.8 33.6 127.9 35.2 65.8 53.5 33.6 15.1 33.9 31.6 18.7 22.8 36.0 18.4 10.4 27.3 73.9 39.2 45.0 37.4 21.1 48.2 31.1 37.4 26.5 27.1 64.7 52.1 39.1 34.6 37.2 47.9 109.8 15.7 28.2 28.4 42.5 11.8 57.4 49.0 46.8 39.2 52.3 9.4 21.5 56.1 28.4 83.4 41.8 16.0 29.9 41.7 77.5 58.0 55.6 16.1 60.4 46.9 38.5 55.5 35.3 16.5 26.3 38.7 46.2 32.6 22.4 26.5 35.4 48.7 71.1 28.8 32.8 64.6 ALOX12 12S-LOX ENSG00000108839 "Arachidonate 12-lipoxygenase, 12S type" P18054 17 6996049-7010754 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Hydrolase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 34.6;esophagus: 49.4;vagina: 105.7" "Cell type enriched" "Detected in some" 6 "Macrophages: 17.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 4.5" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "A-431: 25.5;HEL: 40.4" "Region enriched" "Detected in single" 5 "olfactory bulb: 4.4" "HPA010691, CAB019287, HPA064819" Enhanced Supported "Nuclear speckles,Vesicles,Cytosol" NA NA 49000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "Nuclear speckles, Vesicles" "CAB019287: , HPA010691: AB_1844756, HPA064819: " "unprognostic (3.61e-3)" "unprognostic (6.93e-2)" "unprognostic (7.17e-5)" "unprognostic (9.43e-2)" "unprognostic (6.06e-2)" "unprognostic (2.25e-3)" "unprognostic (2.45e-1)" "unprognostic (3.16e-1)" "unprognostic (3.02e-2)" "unprognostic (1.59e-2)" "unprognostic (3.96e-5)" "unprognostic (4.01e-3)" "unprognostic (2.25e-2)" "unprognostic (1.56e-1)" "unprognostic (2.87e-1)" "unprognostic (5.90e-2)" "unprognostic (3.47e-2)" 1.0 1.5 0.9 3.2 1.5 4.7 0.3 0.1 1.4 34.6 0.6 0.4 1.8 2.2 0.0 49.4 1.2 3.1 1.4 0.4 0.4 0.5 0.2 1.1 3.9 1.3 0.7 1.3 1.9 0.0 0.1 1.1 1.0 0.8 0.1 3.1 20.2 0.0 1.6 21.7 2.0 0.2 0.1 3.3 1.1 1.3 1.2 0.0 1.9 0.1 3.8 1.5 105.7 3.4 25.5 4.2 1.9 1.4 0.0 0.0 1.7 1.6 0.0 0.0 0.0 3.7 0.9 1.3 0.9 0.0 1.4 3.2 0.0 0.1 0.0 2.8 3.2 40.4 6.8 2.8 0.1 0.4 6.5 0.0 0.1 0.0 0.0 2.4 0.0 2.8 2.7 1.4 0.0 0.3 0.5 0.9 1.3 0.2 0.8 1.4 0.8 0.7 0.0 3.2 0.1 0.9 0.7 0.8 0.4 2.4 1.5 1.1 4.6 2.2 1.2 2.1 1.1 0.8 0.3 0.7 1.2 3.0 1.0 2.1 0.9 1.8 0.7 0.4 0.5 1.1 0.5 0.7 0.7 0.6 0.2 0.3 4.5 0.7 0.4 1.3 0.3 13.6 0.9 1.5 0.1 1.4 0.4 0.4 1.3 0.7 1.0 0.1 1.2 3.4 0.0 0.0 0.0 2.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 1.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 17.3 0.0 1.0 0.8 0.0 0.0 2.5 2.4 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 2.5 1.1 0.0 0.1 0.1 0.0 2.0 ALOX12B 12R-LOX ENSG00000179477 "Arachidonate 12-lipoxygenase, 12R type" O75342 17 8072636-8087716 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Isomerase, Lyase, Oxidoreductase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 90.2" "Cell type enhanced" "Detected in some" "Horizontal cells: 1.7;Rod photoreceptor cells: 1.2;Spermatogonia: 1.2;Suprabasal keratinocytes: 1.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 11.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "basophil: 4.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.3" "Cell line enhanced" "Detected in some" "A549: 1.1;HEK 293: 1.3;hTCEpi: 1.6;JURKAT: 2.7;OE19: 1.8" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA024002 Supported Supported Vesicles,Cytosol NA NA 7000 "Cluster 46: Basophils - DNA binding" "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 62: Horizontal cells - Visual perception" Cytosol Vesicles "HPA024002: AB_1844757" "unprognostic (1.27e-2)" "unprognostic (1.59e-2)" "unprognostic (4.28e-3)" "unprognostic (1.38e-2)" "unprognostic (3.94e-3)" "unprognostic (1.18e-2)" "unprognostic (1.26e-1)" "unprognostic (3.04e-1)" "unprognostic (4.40e-2)" "unprognostic (9.55e-2)" "unprognostic (6.66e-3)" "unprognostic (2.27e-1)" "unprognostic (1.79e-1)" "unprognostic (1.02e-1)" "unprognostic (8.01e-2)" "unprognostic (3.46e-2)" 0.0 0.0 0.4 0.1 0.5 0.1 2.1 0.4 0.6 5.7 0.0 0.1 0.3 0.0 0.0 5.6 0.2 0.0 0.0 0.4 0.2 0.2 0.0 0.0 0.5 0.4 0.2 0.0 0.2 1.2 0.1 0.0 0.5 0.4 0.1 0.6 0.8 0.0 0.4 90.2 0.2 0.0 0.1 0.2 0.2 0.2 0.4 0.6 0.0 0.0 19.1 0.0 15.0 0.1 0.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.4 0.2 0.3 0.0 0.0 0.0 1.3 0.0 0.4 0.1 0.0 0.2 0.0 0.0 1.6 0.1 0.5 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.1 0.0 0.2 1.8 0.0 0.9 0.0 0.4 0.4 0.0 0.4 0.5 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.2 0.0 0.4 0.6 0.1 0.2 0.0 0.1 0.5 0.7 0.0 0.1 0.0 0.1 0.0 0.1 0.4 0.5 0.4 0.6 0.4 0.2 0.4 0.2 0.5 0.1 0.4 0.1 0.0 0.0 0.0 0.3 0.3 0.1 0.2 0.5 0.0 0.2 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.4 0.3 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.7 0.5 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.8 0.0 1.2 0.0 0.0 0.0 0.8 1.2 0.0 1.8 0.0 0.0 0.0 0.1 0.1 AMACR "P504S, RACE" ENSG00000242110 "Alpha-methylacyl-CoA racemase" Q9UHK6 5 33986165-34008104 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 134.3;liver: 180.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.7;Hepatocytes: 21.6;Late spermatids: 21.6;Proximal tubular cells: 38.5" "Group enriched" "Detected in all" 4 "liver cancer: 8.8;prostate cancer: 34.5;renal cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 175.4;U-266/84: 98.0" "Low region specificity" "Detected in all" "CAB001809, HPA019527, HPA020912" Enhanced Supported "Vesicles,Plasma membrane" NA NA 70000 "Cluster 14: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" "CAB001809: AB_2305454, HPA019527: AB_10669651, HPA020912: AB_10670034" "unprognostic (8.96e-2)" "unprognostic (5.20e-3)" "prognostic favorable (7.11e-4)" "unprognostic (9.55e-2)" "unprognostic (1.39e-1)" "unprognostic (9.12e-3)" "unprognostic (1.68e-1)" "unprognostic (5.41e-2)" "unprognostic (1.50e-1)" "unprognostic (1.60e-1)" "unprognostic (5.59e-5)" "unprognostic (1.95e-2)" "unprognostic (5.52e-3)" "unprognostic (6.32e-2)" "unprognostic (3.41e-1)" "unprognostic (2.18e-1)" "unprognostic (1.50e-1)" 8.6 15.0 5.9 5.0 5.5 3.0 6.4 4.6 6.0 6.5 4.6 40.0 18.0 4.7 9.6 15.6 6.2 20.5 10.1 5.4 7.8 134.3 180.6 9.2 3.6 5.9 6.4 7.8 13.8 13.0 5.7 7.7 6.6 39.3 42.9 12.0 60.7 12.5 19.2 4.9 15.9 7.0 5.8 5.4 34.8 4.3 8.4 4.8 8.3 14.9 5.6 8.8 8.5 5.8 12.7 20.2 11.1 14.3 7.7 11.9 19.1 16.6 12.2 7.6 5.7 66.1 15.1 4.1 8.7 23.6 28.6 5.8 2.8 12.0 7.7 12.7 10.9 9.8 13.7 19.0 5.4 6.0 3.0 18.1 6.0 9.7 3.6 10.7 8.5 8.3 3.8 14.7 22.4 9.6 5.0 7.6 10.0 9.4 32.9 6.0 18.6 6.5 33.2 62.4 6.1 8.7 27.6 19.3 16.9 9.1 14.9 5.9 15.6 24.6 5.4 6.2 13.6 175.4 98.0 7.4 7.0 12.1 18.8 0.3 6.0 9.3 8.3 8.0 7.0 7.1 7.2 6.4 8.9 5.2 6.6 4.8 10.0 8.7 14.2 4.6 7.9 6.0 5.9 5.5 4.6 6.0 5.4 7.8 5.9 6.4 6.6 5.8 8.4 5.8 0.8 3.2 4.1 0.0 2.2 0.4 0.4 0.9 1.8 4.3 1.4 0.9 1.1 8.6 3.7 1.8 0.0 1.0 2.2 19.7 5.9 0.8 8.9 2.3 1.2 3.0 4.2 2.1 0.0 3.8 1.0 2.9 4.1 1.5 0.0 1.2 1.1 21.6 1.1 5.0 0.0 5.1 4.1 0.9 0.2 21.6 0.6 1.2 0.0 0.0 1.5 9.3 3.1 0.0 0.0 2.6 4.5 2.2 1.6 0.6 4.7 38.5 3.1 0.9 0.0 1.7 3.7 0.7 0.7 3.4 0.6 0.3 1.5 1.2 4.4 0.4 AMBN ENSG00000178522 Ameloblastin Q9NP70 4 70592256-70607288 "Disease related genes, Human disease related genes, Predicted secreted proteins" Biomineralization "Amelogenesis imperfecta" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Microglial cells: 1.9" "Group enriched" "Detected in some" 7 "cervical cancer: 2.6;endometrial cancer: 2.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "HEK 293: 6.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036099 Uncertain Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Nucleoplasm "HPA036099: " "unprognostic (3.22e-1)" 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.3 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AMBP "EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, UTI" ENSG00000106927 "Alpha-1-microglobulin/bikunin precursor" P02760 9 114060127-114078328 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "liver: 10947.9" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 10517.4" "Cancer enriched" "Detected in many" 115 "liver cancer: 2620.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 173 "Hep G2: 1398.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA001497, CAB069436, HPA075585" Approved Approved "Golgi apparatus,Vesicles,Cytosol" "Secreted to blood" NA NA 47000000000 "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Golgi apparatus, Cytosol" "CAB069436: AB_1611916, HPA001497: AB_1078144, HPA075585: " "unprognostic (6.92e-2)" "unprognostic (3.61e-1)" "unprognostic (4.95e-3)" "prognostic favorable (1.20e-4)" "unprognostic (9.79e-2)" "unprognostic (2.90e-1)" "unprognostic (1.04e-3)" "unprognostic (7.59e-2)" "unprognostic (2.83e-2)" "unprognostic (2.04e-1)" "unprognostic (2.14e-1)" "unprognostic (7.84e-2)" "unprognostic (4.36e-2)" "unprognostic (2.89e-3)" "unprognostic (4.66e-2)" "unprognostic (2.97e-3)" "unprognostic (9.45e-3)" 0.7 0.2 0.1 0.0 0.1 0.0 6.4 0.3 0.4 0.2 0.3 0.3 2.3 0.1 0.4 0.3 0.4 160.4 0.5 0.1 0.1 11.0 10947.9 0.3 0.0 0.1 0.1 0.2 125.3 0.0 0.2 0.4 0.1 0.2 0.5 0.2 0.1 0.0 0.2 0.3 0.7 0.0 0.1 3.1 2.6 1.0 0.1 0.1 0.4 0.0 0.2 0.1 0.2 0.0 0.0 6.7 0.1 0.0 0.2 0.1 0.0 0.0 0.5 0.0 0.0 1.8 0.0 1.8 2.1 0.2 0.9 0.5 0.0 0.0 0.0 3.2 0.0 3.0 1.0 1398.1 0.0 5.5 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.1 0.1 0.3 0.0 0.9 3.1 0.0 0.2 8.1 0.4 5.9 0.6 1.7 0.0 2.8 1.1 0.0 0.1 0.0 0.2 1.0 0.0 0.8 0.0 0.4 1.0 0.3 1.5 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 1.5 0.0 19.1 1.5 0.6 0.0 2.2 0.0 1.9 0.4 0.2 2585.0 0.6 1.8 0.0 0.1 0.0 0.6 3.9 216.5 30.4 0.2 0.1 10.0 2.4 219.2 0.1 28.2 0.8 0.1 0.0 1.0 0.0 0.0 181.3 10517.4 0.7 0.0 0.1 1.6 0.0 243.7 0.5 59.4 0.6 0.2 0.0 0.0 3.6 0.0 0.0 0.0 0.0 14.9 1.7 0.0 0.0 0.6 0.6 13.7 0.0 0.0 0.0 0.0 0.5 0.6 0.2 1.1 0.4 1.4 14.3 0.0 1.2 0.3 AMBRA1 "DCAF3, FLJ20294, KIAA1736, WDR94" ENSG00000110497 "Autophagy and beclin 1 regulator 1" Q9C0C7 11 46396414-46594125 "Predicted intracellular proteins" "Autophagy, Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 65.6;Excitatory neurons: 101.4;Inhibitory neurons: 101.9;Microglial cells: 84.3;Oligodendrocyte precursor cells: 84.9;Oligodendrocytes: 136.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 11.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017825, HPA038535" Approved Approved Vesicles,Mitochondria NA NA "Cluster 38: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Mitochondria "CAB017825: , HPA038535: AB_2676068" "unprognostic (1.76e-3)" "unprognostic (1.51e-1)" "unprognostic (1.95e-1)" "unprognostic (1.56e-1)" "unprognostic (6.00e-2)" "unprognostic (1.87e-1)" "unprognostic (1.46e-3)" "unprognostic (7.78e-2)" "unprognostic (1.32e-1)" "unprognostic (1.98e-2)" "unprognostic (5.53e-3)" "unprognostic (2.32e-1)" "prognostic favorable (1.61e-4)" "unprognostic (2.90e-1)" "unprognostic (8.17e-2)" "unprognostic (1.61e-2)" "unprognostic (7.98e-2)" 10.2 16.4 7.5 6.7 9.1 11.6 10.5 7.8 9.1 10.4 7.4 10.1 10.0 11.7 5.8 10.6 10.1 6.4 8.4 7.9 6.4 8.2 9.1 8.6 8.2 6.6 6.1 11.6 8.3 12.3 9.2 7.6 7.3 9.8 7.0 7.8 10.6 7.6 13.0 17.4 9.8 8.8 5.4 10.3 9.7 12.6 8.4 13.5 9.4 8.3 8.1 9.4 10.0 10.8 8.7 23.0 15.5 16.8 16.1 12.0 9.6 8.5 16.1 13.6 14.1 17.4 14.8 17.5 8.5 15.1 16.1 15.4 7.9 15.0 10.0 15.3 25.5 11.9 14.6 22.5 10.5 17.3 14.6 16.7 11.6 8.6 16.3 14.8 14.3 14.9 20.8 11.7 10.2 21.4 22.2 12.2 26.1 19.6 12.4 21.5 21.3 9.7 13.1 15.4 12.5 13.9 14.7 16.6 15.6 10.1 17.2 11.6 15.2 12.5 11.1 14.6 12.8 13.2 11.3 18.1 11.1 9.6 11.3 11.8 2.2 1.7 2.6 1.1 2.2 2.4 1.9 2.0 2.0 2.1 1.9 1.7 2.5 1.4 1.9 2.1 3.2 1.9 7.5 9.1 7.8 9.1 7.9 6.4 6.6 6.1 7.3 5.4 8.4 10.8 5.1 3.2 5.6 65.6 7.2 4.1 2.5 3.4 4.0 6.6 5.1 5.2 8.2 4.3 4.3 0.0 2.1 4.0 5.9 16.0 0.0 6.9 13.8 5.2 5.3 4.7 9.6 10.3 101.4 9.3 2.1 6.7 13.7 8.3 4.5 8.8 3.6 4.1 5.2 5.0 101.9 9.7 2.0 3.5 2.3 6.7 5.3 4.8 5.4 84.3 3.1 3.2 6.2 84.9 136.4 8.4 7.5 7.9 6.6 3.5 8.2 3.2 4.4 5.7 13.1 4.2 5.8 2.1 2.1 7.4 4.5 6.8 6.4 7.9 6.4 4.2 AMER1 "FAM123B, FLJ39827, RP11-403E24.2, WTX" ENSG00000184675 "APC membrane recruitment protein 1" Q5JTC6 X 64185117-64205708 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 15.3" "Cell type enhanced" "Detected in many" "Sertoli cells: 6.6;Theca cells: 6.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 15.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065214, HPA065265" Approved Supported "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" "Nuclear bodies" "Vesicles, Plasma membrane" "HPA065214: AB_2685435, HPA065265: AB_2685450" "unprognostic (1.56e-2)" "unprognostic (8.85e-2)" "unprognostic (6.86e-2)" "unprognostic (2.74e-1)" "unprognostic (2.12e-2)" "unprognostic (1.86e-1)" "unprognostic (3.57e-2)" "unprognostic (1.48e-1)" "unprognostic (8.02e-2)" "unprognostic (1.75e-1)" "unprognostic (6.31e-2)" "unprognostic (3.43e-1)" "unprognostic (4.69e-4)" "unprognostic (1.26e-1)" "unprognostic (1.13e-1)" "unprognostic (6.19e-2)" "unprognostic (2.89e-1)" 1.1 1.4 1.6 1.3 1.5 1.2 1.3 1.8 1.6 1.9 0.1 1.5 1.5 1.9 4.0 2.8 2.2 1.0 1.3 1.0 1.6 1.8 2.1 1.2 1.2 1.5 1.4 6.3 2.0 1.6 0.7 0.8 1.5 1.7 1.3 1.3 2.2 2.2 4.1 2.2 1.3 2.8 0.7 1.3 1.6 0.4 1.9 1.6 1.4 15.3 1.6 1.3 1.3 1.0 3.1 2.2 5.8 4.6 2.2 2.1 4.7 1.4 1.2 2.1 1.3 7.3 1.1 5.9 1.8 3.0 1.6 4.3 12.5 4.1 2.0 2.5 2.5 3.7 4.9 4.9 1.6 7.7 0.9 3.0 5.3 1.6 3.2 1.7 1.2 4.6 5.6 5.9 1.1 3.7 5.2 4.0 15.6 4.0 4.4 11.7 9.4 4.3 0.9 1.0 2.6 3.9 3.7 5.0 1.9 4.8 1.6 2.1 0.8 2.5 5.8 6.7 1.9 3.0 2.2 4.4 1.2 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 1.5 1.8 1.6 1.0 1.6 1.5 1.4 1.5 0.7 1.9 1.0 0.9 0.0 0.0 1.0 1.5 2.2 0.6 0.9 2.8 5.0 1.7 1.5 2.6 4.3 0.3 0.0 2.1 1.1 3.4 1.1 0.0 1.2 0.1 3.3 2.6 1.5 1.2 0.8 0.8 1.6 0.8 1.8 3.6 2.0 0.0 3.9 1.4 2.6 0.4 0.0 1.3 1.0 0.0 1.0 0.3 0.2 2.5 0.5 1.8 1.0 1.2 0.2 0.0 1.0 0.6 0.7 0.5 4.1 2.4 1.2 0.8 0.8 0.0 1.0 6.6 2.3 4.4 0.0 0.2 3.6 2.6 0.7 0.9 6.4 1.6 0.7 AMH MIS ENSG00000104899 "Anti-Mullerian hormone" P03971 19 2249309-2252073 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Differentiation, Gonadal differentiation" "Growth factor" "Disease variant, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "pituitary gland: 3.9;testis: 10.5" "Cell type enriched" "Detected in many" 61 "Granulosa cells: 1567.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 16.9;NTERA-2: 6.4;REH: 7.0;SH-SY5Y: 7.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA066973 Approved Vesicles,Aggresome "Secreted to blood" NA NA 1580000 280000 "Cluster 78: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Aggresome" "HPA066973: AB_2732754" "unprognostic (8.10e-5)" "unprognostic (1.15e-1)" "prognostic unfavorable (9.21e-5)" "unprognostic (8.73e-3)" "unprognostic (1.32e-1)" "unprognostic (1.32e-1)" "unprognostic (8.03e-2)" "unprognostic (8.99e-2)" "unprognostic (2.55e-1)" "unprognostic (3.53e-1)" "unprognostic (5.95e-3)" "unprognostic (1.34e-2)" "unprognostic (8.73e-8)" "unprognostic (4.64e-2)" "unprognostic (4.14e-2)" "unprognostic (2.15e-1)" "unprognostic (2.76e-1)" 0.2 0.2 0.7 0.0 1.2 0.0 0.2 1.2 1.3 0.4 0.0 0.8 0.0 0.3 0.0 0.3 0.4 0.0 0.2 0.2 0.4 0.5 0.3 0.3 0.0 0.4 0.5 1.1 1.2 0.0 3.9 0.0 0.4 0.5 0.0 0.0 0.2 0.0 1.5 0.2 0.4 0.0 0.6 0.2 0.2 10.5 0.6 0.0 0.3 0.0 0.0 0.2 0.3 0.4 2.8 0.2 0.1 0.4 0.0 0.0 4.3 0.6 0.0 0.0 0.0 0.1 0.2 0.5 1.7 0.0 0.0 0.0 0.0 0.0 0.0 3.0 16.9 0.1 0.8 0.0 0.0 0.2 2.7 0.0 0.0 0.0 0.0 0.0 0.0 1.0 2.6 0.4 0.0 0.5 0.1 1.3 6.4 0.0 1.5 7.0 1.4 0.9 0.0 0.2 0.4 7.7 0.1 0.0 1.7 0.0 0.8 0.0 0.7 0.6 1.3 0.9 2.5 4.7 3.7 0.8 0.3 1.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.2 1.2 1.3 0.2 0.4 0.4 0.5 0.4 0.6 0.6 0.4 0.3 0.0 0.0 2.0 0.0 0.1 0.2 0.1 0.6 12.1 1.6 2.2 1.1 1.5 0.0 0.0 2.1 0.3 0.4 1.1 0.0 0.3 2.0 0.7 0.8 0.5 1.2 0.4 1.6 0.2 0.3 0.4 0.0 1.5 0.0 1567.5 0.7 0.3 0.1 8.4 11.5 1.0 0.0 0.0 0.0 9.2 1.5 2.3 0.0 1.9 0.1 6.3 0.0 1.0 2.2 0.0 0.0 0.4 0.1 0.1 0.9 0.2 0.1 2.3 0.0 9.2 25.6 8.1 0.6 0.7 0.1 0.0 0.4 0.0 0.8 0.2 AMHR2 "MISR2, MISRII" ENSG00000135409 "Anti-Mullerian hormone receptor type 2" Q16671 12 53423855-53431672 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 41.5;ovary: 33.1" "Group enriched" "Detected in some" 4 "granulocytes: 26.0;Granulosa cells: 36.1;Theca cells: 94.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "HEL: 40.1;K-562: 22.2" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 11 "hippocampal formation: 9.4" "HPA060228, HPA069636" Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 52: Non-specific - Transcription" Vesicles "Nucleoplasm, Cytosol" "HPA060228: AB_2684227, HPA069636: AB_2686163" "unprognostic (5.79e-2)" "unprognostic (3.65e-1)" "unprognostic (3.98e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (4.61e-3)" "unprognostic (2.33e-1)" "unprognostic (1.44e-2)" "unprognostic (2.91e-1)" "unprognostic (4.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.32e-1)" "unprognostic (2.15e-2)" "unprognostic (3.34e-2)" "unprognostic (1.42e-1)" "unprognostic (2.04e-1)" "unprognostic (1.97e-1)" 0.6 41.5 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.3 0.4 0.1 0.5 0.0 0.3 0.0 0.9 0.4 0.0 0.0 0.2 33.1 12.5 0.4 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 4.2 0.1 0.1 0.0 0.0 5.7 0.7 9.1 0.5 0.0 0.0 1.8 0.0 0.2 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.6 40.1 0.0 0.8 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 22.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 3.5 2.6 0.0 0.1 1.5 0.0 4.2 0.1 2.1 0.1 2.7 0.0 0.1 26.0 36.1 11.4 0.3 0.1 0.0 0.0 0.0 0.0 1.2 0.0 2.5 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.1 0.3 0.0 0.0 0.3 0.8 94.9 0.1 0.0 ANAPC1 "APC1, MCPR, TSG24" ENSG00000153107 "Anaphase promoting complex subunit 1" Q9H1A4 2 111611639-111884690 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Cancer-related genes, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036329, HPA036330, HPA042998" Approved Approved Vesicles NA NA "Cluster 15: NK-cells - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 32: Non-specific - Translation" Vesicles "HPA036329: AB_10670714, HPA036330: AB_2675065, HPA042998: AB_2678263" "unprognostic (1.74e-1)" "unprognostic (5.04e-2)" "unprognostic (1.10e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.49e-1)" "unprognostic (2.15e-1)" "unprognostic (2.16e-4)" "unprognostic (1.23e-1)" "unprognostic (3.94e-2)" "unprognostic (2.59e-1)" "unprognostic (3.65e-2)" "unprognostic (1.23e-1)" "unprognostic (2.13e-2)" "unprognostic (1.94e-1)" "unprognostic (1.98e-1)" "unprognostic (1.15e-2)" "unprognostic (1.92e-1)" 6.4 4.8 4.1 9.5 5.1 8.3 9.2 4.8 5.1 6.9 9.8 9.9 8.3 8.0 4.9 8.1 7.8 5.8 5.8 4.7 3.6 6.2 5.6 5.4 12.1 4.1 4.1 8.4 6.3 10.4 4.6 7.7 5.1 6.4 10.5 7.9 5.4 6.2 12.2 6.8 6.5 7.6 3.7 7.8 6.6 10.2 4.0 12.6 6.3 9.4 12.4 8.4 5.8 5.2 42.4 31.0 33.1 23.9 14.9 18.4 32.6 25.0 18.8 30.3 26.5 60.4 26.6 72.7 19.9 23.0 36.0 35.4 51.0 28.4 40.4 31.7 31.9 81.6 27.6 37.1 14.3 85.0 27.4 13.8 14.3 44.9 40.8 15.4 29.5 34.9 75.8 30.8 21.5 20.2 51.9 25.5 50.3 18.3 26.1 51.1 39.4 41.1 19.1 41.6 26.2 16.0 26.2 23.9 22.8 21.8 14.1 30.1 20.9 26.5 28.5 21.7 26.9 23.0 52.5 67.1 21.5 36.9 21.9 0.0 2.1 0.6 4.2 2.2 6.1 4.0 3.8 3.6 3.9 3.1 5.4 5.2 0.4 4.8 1.9 1.8 1.8 3.3 4.1 5.1 4.8 5.1 4.7 3.6 4.1 4.1 5.1 3.7 4.0 5.2 14.5 3.2 8.2 17.0 20.3 14.3 20.5 7.6 22.2 11.2 12.1 11.8 7.5 8.6 6.0 3.7 14.6 12.2 25.4 7.2 5.9 5.9 6.6 13.5 13.4 11.0 11.4 17.9 32.5 5.9 12.7 12.0 12.2 11.7 8.2 19.2 8.6 12.8 9.0 20.2 32.6 11.1 14.2 8.4 11.8 8.6 10.2 12.2 7.2 12.2 8.8 7.7 13.4 21.6 31.3 7.1 5.4 9.4 14.4 24.6 5.6 8.8 8.2 16.0 13.1 15.9 11.5 17.3 21.0 18.0 20.2 6.7 21.2 12.2 14.5 23.4 ANAPC15 "APC15, C11orf51, DKFZP564M082, HSPC020" ENSG00000110200 "Anaphase promoting complex subunit 15" P60006 11 72106378-72112780 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036596 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm Vesicles "HPA036596: AB_10671961" "unprognostic (1.17e-1)" "unprognostic (5.83e-2)" "unprognostic (4.23e-2)" "unprognostic (3.05e-2)" "unprognostic (1.86e-2)" "unprognostic (2.09e-2)" "prognostic unfavorable (4.37e-4)" "unprognostic (9.18e-2)" "unprognostic (3.35e-2)" "prognostic favorable (2.55e-4)" "unprognostic (9.34e-3)" "unprognostic (1.76e-1)" "unprognostic (1.26e-3)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (2.77e-1)" "unprognostic (9.08e-2)" 28.9 44.2 47.0 30.0 47.5 95.9 30.0 47.8 61.1 24.3 45.8 67.1 30.7 43.4 38.3 53.2 30.4 18.3 62.2 47.2 47.7 48.8 44.0 30.0 43.5 46.4 46.8 22.4 39.2 25.4 32.8 19.2 47.2 52.0 40.6 42.8 39.9 38.8 95.2 39.6 40.1 31.9 46.4 41.2 46.5 72.0 46.3 72.6 44.7 64.3 44.3 41.6 29.5 49.0 74.0 109.4 87.5 55.8 25.5 41.2 41.4 77.1 70.1 121.3 80.2 128.8 78.4 98.8 72.9 110.3 59.0 122.6 133.4 144.0 113.9 64.0 63.3 113.1 124.9 84.5 30.2 110.8 101.3 43.2 56.2 68.9 91.6 45.4 80.7 136.7 83.3 66.6 80.0 127.2 214.5 102.9 70.9 155.3 62.3 89.6 217.4 67.2 106.1 50.5 61.9 53.8 79.0 76.5 127.0 46.8 89.6 58.6 73.4 55.5 72.9 110.5 82.8 68.0 71.5 125.3 34.0 87.8 31.7 29.7 168.5 136.3 73.3 114.2 78.0 94.5 93.4 86.3 148.8 71.4 110.9 101.5 68.4 72.4 107.4 119.1 153.0 124.1 47.0 47.5 47.8 61.1 47.2 47.7 46.4 46.8 47.2 46.4 46.3 49.0 20.1 16.0 16.5 2.9 36.1 41.8 71.2 83.5 44.3 32.9 43.2 55.6 3.9 12.8 50.6 23.9 27.1 84.7 40.5 82.9 123.3 49.4 15.4 38.8 21.3 22.8 49.6 34.1 7.1 102.7 78.8 18.3 36.7 27.8 30.4 27.2 15.0 44.1 82.8 13.5 7.3 66.2 61.1 48.5 47.5 13.4 6.8 48.0 26.6 1.0 58.8 44.1 36.0 5.5 5.2 53.1 61.4 23.0 47.1 43.8 56.2 123.6 45.6 43.3 19.7 16.0 35.3 115.9 139.9 53.8 41.1 46.7 41.1 32.3 71.5 61.7 ANGPTL4 "ARP4, FIAF, HFARP, NL2, PGAR, pp1158" ENSG00000167772 "Angiopoietin like 4" Q9BY76 19 8363289-8374370 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Lipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 195.8;breast: 165.0;liver: 183.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 318.9;Hepatocytes: 148.4;Pancreatic endocrine cells: 230.4;Proximal enterocytes: 146.3;Skeletal myocytes: 198.3" "Cancer enriched" "Detected in all" 4 "renal cancer: 212.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 3.3" "Lineage enriched" "Detected in single" 10 "granulocytes: 3.3" "Cell line enhanced" "Detected in many" "ASC diff: 54.6;HBEC3-KT: 226.5;LHCN-M2: 60.9;TIME: 114.6;U-138 MG: 65.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA007879, CAB033770" Approved Approved Nucleoplasm,Vesicles "Secreted to blood" NA NA 7750000 3100000 "Cluster 41: Basophils - Cellular respiration" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Vesicles" "CAB033770: AB_2057427, HPA007879: AB_1078158" "unprognostic (1.26e-1)" "unprognostic (5.29e-3)" "prognostic unfavorable (7.53e-4)" "unprognostic (1.88e-2)" "unprognostic (7.68e-3)" "unprognostic (3.58e-1)" "unprognostic (1.03e-2)" "prognostic unfavorable (9.50e-4)" "unprognostic (3.18e-1)" "unprognostic (3.90e-3)" "unprognostic (9.69e-3)" "unprognostic (2.87e-1)" "prognostic unfavorable (1.34e-5)" "unprognostic (1.18e-3)" "unprognostic (3.04e-1)" "unprognostic (7.68e-2)" "unprognostic (2.00e-2)" 195.8 23.0 25.2 15.4 31.8 1.4 165.0 26.2 32.6 18.8 14.0 25.6 11.5 6.8 0.1 41.2 7.9 9.4 45.4 27.7 27.0 51.9 183.7 46.6 2.0 30.1 37.6 9.1 70.8 1.0 16.1 18.3 27.2 30.4 0.9 3.2 19.1 2.6 24.8 30.2 28.0 6.0 27.3 13.1 21.7 6.7 33.8 0.7 34.1 6.2 2.8 26.6 32.1 33.7 0.1 2.2 1.2 3.3 54.6 12.0 0.7 4.4 0.5 0.7 0.2 0.0 20.9 0.2 30.6 8.8 4.5 3.0 0.0 226.5 0.4 1.9 0.4 0.3 0.9 0.9 1.2 0.1 0.2 5.6 1.0 34.0 0.7 6.2 17.4 0.6 1.1 0.5 60.9 1.8 0.2 2.1 0.3 0.0 1.8 1.3 0.1 1.0 11.1 4.0 0.2 0.5 26.2 2.7 4.3 1.5 6.8 0.4 114.6 65.1 0.3 33.3 0.0 0.3 0.1 0.2 44.9 0.0 12.4 3.3 0.1 0.4 0.1 0.0 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.9 0.3 0.0 0.1 0.2 0.1 25.2 31.8 26.2 32.6 27.7 27.0 30.1 37.6 27.2 27.3 33.8 33.7 53.5 38.5 5.8 128.0 1.2 14.0 39.8 318.9 17.1 0.2 71.8 49.0 5.3 1.5 85.7 14.7 0.0 7.4 2.5 17.1 0.0 107.1 0.7 4.2 6.9 28.9 0.0 0.0 0.4 18.0 111.2 89.1 46.9 13.8 2.5 1.5 17.9 148.4 8.3 0.0 0.6 14.2 16.2 1.6 10.3 2.2 88.0 5.0 8.8 2.8 2.0 2.7 0.0 1.0 4.5 230.4 8.4 131.7 1.0 38.3 146.3 4.5 19.0 0.1 32.9 198.3 121.5 0.0 3.1 21.8 11.5 40.1 2.3 20.7 6.7 77.7 ANKRD13B FLJ25555 ENSG00000198720 "Ankyrin repeat domain 13B" Q86YJ7 17 29589769-29614761 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 27.4;Endometrial stromal cells: 24.2;Excitatory neurons: 19.4;Horizontal cells: 16.8;Late spermatids: 44.7;Oligodendrocytes: 17.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 52.0;SH-SY5Y: 57.6;SK-BR-3: 48.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051886, HPA063748" Uncertain Supported Vesicles NA NA "Cluster 43: Testis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA051886: AB_2681652, HPA063748: AB_2685112" "unprognostic (1.61e-1)" "unprognostic (2.01e-1)" "unprognostic (1.27e-1)" "unprognostic (1.66e-2)" "unprognostic (1.53e-1)" "unprognostic (2.45e-1)" "unprognostic (3.10e-4)" "unprognostic (1.84e-1)" "unprognostic (1.84e-1)" "unprognostic (1.03e-2)" "prognostic favorable (7.58e-4)" "unprognostic (3.94e-2)" "prognostic unfavorable (5.92e-6)" "unprognostic (9.93e-2)" "unprognostic (1.18e-1)" "unprognostic (3.94e-2)" "unprognostic (5.36e-3)" 12.0 3.7 12.5 1.7 14.3 0.7 7.5 11.9 15.9 16.3 0.0 10.2 0.8 13.6 0.8 6.5 12.0 3.7 10.3 13.9 6.2 2.8 1.2 5.5 1.6 13.4 9.4 15.1 3.7 1.6 14.6 0.9 10.4 7.7 0.6 2.0 4.3 1.8 9.6 7.5 4.5 2.9 7.2 2.6 4.9 18.9 10.8 0.9 5.8 1.3 0.3 10.0 11.6 22.9 6.6 11.5 13.3 35.4 8.2 8.0 5.1 2.0 1.2 1.4 2.7 6.1 1.4 7.4 6.4 2.8 4.9 24.3 7.2 7.8 0.2 14.8 23.5 2.3 22.3 5.3 3.5 2.4 4.6 7.9 10.2 2.2 5.8 6.4 10.1 12.8 6.0 6.1 1.9 5.9 16.0 7.5 11.4 6.8 9.7 33.4 9.5 23.4 3.0 2.2 52.0 57.6 3.9 48.0 4.3 1.2 7.4 4.4 6.7 7.4 7.2 5.2 7.2 11.4 15.7 9.2 5.2 12.1 4.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 14.3 11.9 15.9 13.9 6.2 13.4 9.4 10.4 7.2 10.8 22.9 2.6 0.0 0.0 6.8 0.1 1.7 1.0 0.7 3.4 4.5 1.8 2.7 2.3 0.0 0.4 0.0 2.1 0.1 0.6 0.6 1.9 1.6 27.4 0.9 24.2 2.4 3.0 1.7 19.4 0.6 0.2 5.5 2.6 1.0 0.0 3.8 1.4 0.6 0.1 16.8 14.6 0.8 0.0 0.3 1.6 44.7 14.6 0.3 0.0 0.0 0.0 1.8 0.0 11.1 17.8 0.5 0.0 7.5 0.5 3.2 0.1 0.2 0.0 5.2 0.0 2.4 2.5 6.0 4.7 2.6 1.7 0.1 0.7 1.0 1.1 1.5 ANKRD2 ARPP ENSG00000165887 "Ankyrin repeat domain 2" Q9GZV1 10 97572499-97583884 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 63 "heart muscle: 437.1;skeletal muscle: 981.2;tongue: 823.8" "Cell type enriched" "Detected in some" 6 "Cardiomyocytes: 218.3" "Cancer enhanced" "Detected in many" "renal cancer: 4.9;testis cancer: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 17.6;BJ hTERT+ SV40 Large T+: 7.3;HaCaT: 13.0;RPTEC TERT1: 17.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA040842, HPA040884" Enhanced Enhanced Vesicles NA NA 110000 "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" Vesicles "HPA040842: AB_10963794, HPA040884: AB_10969453" "unprognostic (1.27e-2)" "unprognostic (9.99e-2)" "unprognostic (2.86e-1)" "unprognostic (1.39e-2)" "unprognostic (1.37e-1)" "unprognostic (1.61e-2)" "unprognostic (2.53e-1)" "unprognostic (5.60e-3)" "unprognostic (2.17e-1)" "unprognostic (3.12e-1)" "unprognostic (4.91e-2)" "unprognostic (2.22e-1)" "unprognostic (1.05e-2)" "unprognostic (3.69e-3)" "unprognostic (4.56e-2)" "unprognostic (1.39e-1)" "unprognostic (2.13e-1)" 0.4 0.8 2.5 0.1 2.3 0.0 0.5 2.5 3.7 0.2 2.0 0.3 0.0 0.3 0.3 1.0 0.1 0.3 437.1 2.5 2.7 11.8 0.3 0.8 0.2 2.5 2.4 0.1 0.9 0.0 0.6 0.0 2.5 2.9 0.0 0.3 3.4 0.9 981.2 2.7 0.2 0.2 1.9 0.1 0.2 0.5 2.7 0.0 0.5 823.8 0.1 0.1 0.4 2.5 17.6 5.4 0.0 0.0 0.2 0.0 0.4 0.9 0.0 7.3 4.7 0.3 5.3 0.0 0.6 0.2 0.4 13.0 0.0 4.7 5.0 0.2 0.2 0.0 0.3 0.0 0.5 0.0 0.0 0.8 2.1 4.3 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 17.4 0.8 0.0 0.0 0.0 4.4 0.0 0.4 2.1 0.3 0.0 0.1 1.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 2.3 2.5 3.7 2.5 2.7 2.5 2.4 2.5 1.9 2.7 2.5 0.1 0.0 0.0 1.3 0.0 0.1 0.7 1.7 1.2 0.0 0.2 0.4 218.3 2.8 0.2 3.7 0.0 0.2 0.0 0.0 31.3 1.2 0.6 0.1 0.3 1.6 0.0 0.0 1.3 0.2 0.4 1.0 0.0 0.1 0.0 0.7 0.4 0.2 0.1 0.0 1.5 0.0 0.0 0.0 0.4 0.2 0.0 0.3 0.0 0.0 1.6 0.0 0.0 0.5 0.4 0.9 0.0 1.9 0.0 0.1 0.0 19.1 0.0 0.1 0.0 13.6 1.1 2.5 3.5 0.6 0.3 0.3 0.2 0.1 0.0 0.5 ANKRD26 "KIAA1074, THC2" ENSG00000107890 "Ankyrin repeat domain 26" Q9UPS8 10 26973793-27100494 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 130.6;Cone photoreceptor cells: 200.1;Excitatory neurons: 136.8;Inhibitory neurons: 185.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "HPA040654, HPA041460" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 37: B-cells - Transcription" "Cluster 54: Non-specific - Microtubule organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus, Vesicles" "HPA040654: AB_10795370, HPA041460: AB_10795120" "unprognostic (1.92e-1)" "unprognostic (3.41e-1)" "unprognostic (2.99e-1)" "unprognostic (1.46e-1)" "unprognostic (1.02e-1)" "unprognostic (2.09e-2)" "unprognostic (1.86e-5)" "unprognostic (2.96e-2)" "unprognostic (1.01e-1)" "unprognostic (4.08e-2)" "unprognostic (1.53e-2)" "unprognostic (1.03e-2)" "unprognostic (2.53e-3)" "unprognostic (5.35e-2)" "unprognostic (1.04e-2)" "unprognostic (1.99e-2)" "unprognostic (2.99e-1)" 2.3 2.6 4.7 1.6 5.4 1.5 3.8 5.9 8.6 3.9 5.0 2.5 1.7 3.3 3.0 2.0 3.0 2.0 4.1 4.4 4.0 2.7 2.8 1.9 3.5 4.7 3.8 4.0 2.6 4.0 4.6 3.2 2.7 2.6 2.8 10.0 2.3 2.5 6.7 2.5 2.0 2.5 2.8 2.5 2.2 4.0 4.9 3.1 2.7 7.5 2.2 2.2 2.7 5.8 7.7 5.4 9.8 3.7 6.1 6.7 3.4 10.1 3.7 9.2 8.5 5.2 5.1 17.9 3.1 4.7 6.5 8.1 9.6 4.7 11.0 7.4 7.2 1.1 7.9 7.9 4.5 4.5 1.2 4.7 2.9 9.5 3.2 7.5 8.4 5.5 14.8 4.8 9.3 4.3 5.5 2.8 3.9 2.8 3.5 6.6 13.8 4.3 5.7 3.1 8.5 4.7 9.6 2.0 8.1 7.1 8.5 3.1 7.6 7.7 5.2 9.9 5.7 1.9 2.6 11.7 7.3 9.9 3.5 1.0 0.2 0.2 0.2 0.1 0.7 1.2 0.4 0.4 0.3 0.6 1.6 0.5 0.1 1.6 0.1 2.1 0.4 0.2 4.7 5.4 5.9 8.6 4.4 4.0 4.7 3.8 2.7 2.8 4.9 5.8 19.5 22.4 28.8 130.6 14.3 4.2 7.6 9.0 8.6 77.8 13.5 17.7 70.9 7.2 19.4 3.7 200.1 24.8 8.6 8.3 5.9 14.5 19.0 47.7 38.6 20.4 20.9 6.3 136.8 13.1 13.1 21.3 8.2 16.5 5.1 43.5 13.6 8.3 11.9 79.1 185.9 9.3 10.2 5.7 5.4 6.4 30.4 11.8 3.6 45.0 12.4 45.0 18.6 87.0 67.2 11.3 4.2 27.1 7.8 5.3 12.1 5.6 49.5 117.9 32.9 30.1 15.6 60.7 57.2 8.9 8.0 13.7 12.9 46.1 14.6 5.0 ANKRD27 "DKFZp434L0718, FLJ00040, VARP" ENSG00000105186 "Ankyrin repeat domain 27" Q96NW4 19 32597006-32676597 "Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 137.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042769 Approved Supported Vesicles,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 36: HEL - Hemostasis" "Cluster 59: Non-specific - Transcription" Vesicles Cytosol "HPA042769: AB_10796584" "unprognostic (2.16e-3)" "unprognostic (6.04e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (1.63e-1)" "unprognostic (1.21e-2)" "prognostic unfavorable (1.21e-5)" "unprognostic (9.02e-2)" "unprognostic (1.07e-1)" "unprognostic (1.61e-2)" "unprognostic (2.90e-2)" "unprognostic (6.22e-3)" "unprognostic (3.74e-2)" "unprognostic (2.14e-1)" "unprognostic (4.94e-2)" "unprognostic (4.07e-1)" "unprognostic (2.26e-2)" 8.9 7.4 10.8 8.9 12.9 10.4 8.7 12.1 12.6 10.3 21.5 17.2 7.6 10.0 8.8 14.3 8.0 7.7 9.6 11.8 9.8 9.7 4.4 10.3 11.1 12.0 12.9 8.3 7.2 9.3 6.8 13.6 12.4 12.3 11.9 11.7 9.7 13.5 20.7 12.4 10.7 11.6 8.9 9.0 11.0 17.3 12.1 16.7 13.3 10.8 11.5 16.9 11.1 11.8 32.0 36.0 11.5 20.8 23.5 18.0 28.1 18.0 18.0 19.4 25.4 28.8 19.0 34.7 16.5 23.0 20.4 19.4 29.6 22.3 32.0 47.3 15.1 137.9 13.7 23.9 29.4 53.5 47.6 13.1 28.8 20.9 33.8 13.5 19.7 25.3 37.5 76.3 15.1 31.5 20.8 46.2 6.0 40.2 13.8 30.6 15.6 12.7 15.6 30.5 21.3 8.6 17.6 29.6 21.0 15.2 12.4 25.7 18.5 21.1 22.4 19.6 28.0 19.7 12.7 23.8 21.0 51.8 13.8 36.5 11.1 28.5 13.9 15.7 17.5 7.5 14.3 15.6 12.6 6.9 10.9 11.7 9.0 30.6 13.3 6.2 13.2 13.3 10.8 12.9 12.1 12.6 11.8 9.8 12.0 12.9 12.4 8.9 12.1 11.8 6.8 16.0 9.4 18.3 10.0 15.6 5.5 5.6 14.2 9.4 9.0 5.1 9.2 7.2 5.7 9.2 20.9 14.9 9.7 9.3 0.0 3.3 5.1 7.5 9.4 7.1 9.1 26.5 35.5 5.9 10.6 7.6 5.6 11.6 12.0 10.1 4.6 4.8 8.4 11.8 16.3 9.6 8.2 12.0 12.1 16.2 10.8 8.7 16.0 12.2 6.0 5.8 9.2 11.1 18.7 7.1 10.3 9.4 8.0 10.0 10.8 7.7 7.1 14.7 0.0 6.8 9.3 4.1 17.1 14.7 15.5 15.2 14.0 7.2 8.9 8.4 ANKRD31 FLJ40191 ENSG00000145700 "Ankyrin repeat domain 31" Q8N7Z5 5 75068275-75236911 "Predicted intracellular proteins" "DNA recombination, Meiosis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 4.9" "Group enriched" "Detected in some" 7 "Spermatocytes: 148.9;Spermatogonia: 37.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA038028, HPA057566" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles,Centrosome NA NA "Cluster 35: T-regs - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Centrosome" "Nucleoli, Vesicles" "HPA038028: AB_10672615, HPA057566: AB_2683470" "unprognostic (1.37e-1)" "unprognostic (4.28e-2)" "unprognostic (5.25e-2)" "unprognostic (5.57e-2)" "unprognostic (1.65e-1)" "unprognostic (5.72e-2)" "unprognostic (4.81e-2)" "unprognostic (2.52e-2)" "unprognostic (3.63e-1)" "unprognostic (1.83e-1)" "unprognostic (1.02e-2)" "unprognostic (1.69e-1)" "unprognostic (3.00e-2)" "unprognostic (4.46e-2)" "unprognostic (5.48e-2)" "unprognostic (1.24e-2)" "unprognostic (1.40e-1)" 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.3 0.0 0.0 0.1 0.1 0.1 0.7 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.3 0.2 0.1 0.2 0.1 0.0 0.2 0.1 0.0 0.3 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 4.9 0.1 0.2 0.0 0.0 0.0 0.0 0.4 0.3 0.2 0.1 0.1 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.2 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.3 0.2 0.2 0.1 0.3 0.1 0.0 0.5 5.2 0.4 0.4 0.4 0.5 0.6 3.3 0.8 1.1 1.1 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.3 3.6 2.8 0.8 0.1 0.0 0.8 5.8 0.2 0.6 0.4 4.1 0.4 12.0 0.5 0.4 0.0 0.1 1.7 5.4 0.0 0.0 0.0 0.0 4.7 1.5 0.1 0.0 1.0 0.1 1.3 0.0 3.0 5.6 0.1 0.1 0.4 1.3 0.0 0.1 0.3 1.2 2.2 13.1 0.6 0.4 148.9 37.7 0.4 0.1 0.3 1.1 0.7 0.1 0.2 ANKRD39 MGC41816 ENSG00000213337 "Ankyrin repeat domain 39" Q53RE8 2 96836611-96858016 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 263.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042678 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm Vesicles "HPA042678: AB_10794532" "unprognostic (6.26e-2)" "unprognostic (1.32e-1)" "prognostic unfavorable (2.26e-4)" "unprognostic (9.53e-2)" "unprognostic (2.28e-2)" "unprognostic (2.09e-1)" "unprognostic (4.03e-2)" "unprognostic (1.68e-1)" "unprognostic (9.25e-2)" "unprognostic (3.12e-3)" "prognostic favorable (6.12e-5)" "unprognostic (6.15e-2)" "prognostic unfavorable (6.78e-9)" "unprognostic (3.16e-1)" "unprognostic (1.14e-1)" "unprognostic (5.03e-2)" "prognostic favorable (5.21e-4)" 6.8 14.1 13.1 7.2 13.4 10.5 7.3 15.9 18.7 6.9 8.9 11.0 8.3 10.2 2.9 7.5 10.2 5.9 14.9 13.2 13.2 7.9 14.8 6.2 11.0 13.0 12.5 6.6 8.3 12.3 16.0 5.5 13.4 8.2 4.0 5.3 7.4 6.8 7.9 8.7 7.4 6.2 12.3 9.7 8.3 4.1 12.5 7.4 5.8 4.5 6.5 8.5 6.8 14.5 24.0 15.7 8.8 19.2 2.9 5.7 21.1 18.1 8.4 22.5 17.3 38.8 9.9 15.2 26.4 13.2 17.7 10.3 11.2 17.3 5.0 17.6 34.1 11.0 14.4 53.5 14.8 24.9 25.6 11.0 10.2 20.5 7.9 8.4 16.3 31.1 23.5 263.1 8.4 37.9 23.3 19.5 11.1 8.1 35.8 17.8 6.2 85.3 11.8 12.3 20.3 13.3 13.1 30.6 23.7 8.0 9.3 13.5 8.2 14.0 13.8 16.0 32.5 13.4 16.2 25.3 14.0 28.5 14.9 20.1 16.0 13.4 44.4 20.8 37.7 41.6 43.6 39.3 16.6 33.2 24.0 29.2 8.3 37.6 23.5 70.4 71.0 21.1 13.1 13.4 15.9 18.7 13.2 13.2 13.0 12.5 13.4 12.3 12.5 14.5 14.0 6.4 8.9 2.6 16.9 9.4 17.2 25.7 9.1 25.2 14.9 23.2 19.5 18.6 17.6 9.2 4.2 44.9 28.1 15.1 25.4 28.8 6.1 18.1 18.7 12.9 18.6 13.5 4.6 32.0 38.6 14.9 11.7 11.8 12.7 12.7 10.8 32.0 31.6 33.7 5.3 19.9 18.3 11.1 10.4 2.9 12.5 13.8 28.4 1.0 9.3 15.9 37.0 4.5 5.9 41.3 11.3 14.7 26.2 12.5 23.4 29.4 35.0 29.8 26.3 24.9 18.8 13.6 14.3 18.9 17.8 21.6 24.4 33.5 16.9 15.7 ANKRD6 KIAA0957 ENSG00000135299 "Ankyrin repeat domain 6" Q9Y2G4 6 89433152-89633834 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 26.7" "Cell type enhanced" "Detected in many" "Astrocytes: 35.3;Granulosa cells: 53.9;Inhibitory neurons: 54.3;Oligodendrocyte precursor cells: 32.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 15.1;BEWO: 44.9;HAP1: 15.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020693, HPA035694, HPA064642" Approved Enhanced Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Vesicles "CAB020693: , HPA035694: AB_2674739, HPA064642: AB_2685310" "unprognostic (3.80e-1)" "unprognostic (3.16e-2)" "unprognostic (2.39e-3)" "unprognostic (2.03e-1)" "unprognostic (1.36e-1)" "unprognostic (3.06e-2)" "unprognostic (2.91e-2)" "unprognostic (3.29e-2)" "unprognostic (4.95e-2)" "unprognostic (2.09e-1)" "unprognostic (7.84e-2)" "unprognostic (2.26e-1)" "unprognostic (1.81e-1)" "unprognostic (1.43e-3)" "unprognostic (2.28e-1)" "unprognostic (3.01e-1)" "unprognostic (2.10e-1)" 3.5 1.8 15.3 2.6 16.5 1.4 3.6 24.7 14.8 5.0 10.5 2.8 0.7 5.2 1.8 4.1 9.1 4.7 7.8 13.6 17.6 4.9 4.1 4.9 2.3 11.2 9.7 12.8 3.8 6.5 3.4 3.7 9.5 2.6 0.9 3.0 5.1 1.7 3.8 1.6 1.5 4.0 8.8 1.8 2.2 5.3 26.7 3.8 4.7 3.1 1.7 3.5 2.8 6.7 0.0 2.0 15.1 6.6 0.1 0.7 44.9 0.2 0.2 0.1 1.0 0.5 1.2 0.0 1.5 0.0 7.0 0.0 15.2 8.2 0.6 0.1 10.0 5.5 0.0 0.5 0.2 0.0 2.0 1.0 2.3 0.0 0.0 0.0 1.6 1.4 0.4 3.6 0.0 1.9 0.2 0.6 4.4 0.6 1.5 5.7 0.0 0.0 2.9 8.0 9.5 3.6 1.2 10.7 4.6 9.0 3.1 3.5 0.0 2.3 0.9 0.2 1.3 0.5 0.1 0.0 0.4 0.0 1.8 0.0 0.1 0.9 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 15.3 16.5 24.7 14.8 13.6 17.6 11.2 9.7 9.5 8.8 26.7 6.7 6.8 16.0 19.4 35.3 1.6 0.9 5.6 4.7 10.2 0.9 4.4 4.6 5.7 11.5 6.4 1.8 12.5 3.6 1.3 0.1 11.7 5.9 2.6 12.0 2.9 5.7 1.8 1.7 23.8 11.2 10.8 7.2 5.6 3.9 10.8 53.9 5.0 2.8 2.6 0.0 54.3 0.0 8.2 2.6 2.1 6.1 9.6 2.5 3.6 25.3 2.9 7.2 3.1 32.6 6.6 5.1 0.1 27.8 4.0 2.5 0.0 4.1 8.2 1.7 6.6 3.4 5.2 5.3 5.3 4.3 1.1 1.9 1.5 4.3 0.0 4.9 ANO10 "FLJ10375, MGC47890, SCAR10, TMEM16K" ENSG00000160746 "Anoctamin 10" Q9NW15 3 43354859-43691594 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 123.3;Excitatory neurons: 77.4;Inhibitory neurons: 97.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016624, HPA051569" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Vesicles "HPA016624: , HPA051569: AB_2681537" "unprognostic (1.51e-3)" "unprognostic (1.38e-2)" "prognostic favorable (6.70e-4)" "prognostic favorable (1.11e-4)" "unprognostic (4.23e-1)" "unprognostic (2.69e-2)" "prognostic unfavorable (3.19e-4)" "unprognostic (7.99e-3)" "unprognostic (1.03e-2)" "unprognostic (1.56e-1)" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "prognostic favorable (6.41e-6)" "unprognostic (9.83e-3)" "unprognostic (1.22e-1)" "unprognostic (5.19e-3)" "unprognostic (5.71e-2)" 26.6 14.1 17.6 15.1 18.6 33.0 21.8 23.9 20.9 22.3 18.4 39.4 61.1 21.6 13.6 25.3 13.9 19.4 12.7 18.1 21.1 29.9 14.1 16.9 7.6 22.7 22.9 13.9 15.2 23.7 13.9 18.1 23.2 14.2 33.7 10.1 28.6 20.2 15.5 32.0 54.7 28.0 19.6 9.1 13.5 13.0 19.8 7.1 24.5 11.6 9.7 18.1 21.5 24.1 30.6 23.6 26.1 27.4 101.1 53.5 31.2 87.7 141.1 42.0 54.4 16.2 27.5 3.1 27.4 114.8 43.1 16.3 20.6 47.0 52.6 33.6 14.2 39.4 28.7 17.7 43.9 7.2 31.1 50.5 36.3 53.6 71.8 79.4 100.3 18.7 30.8 24.9 95.2 20.8 7.8 5.2 31.3 23.7 28.6 6.3 18.7 10.2 85.5 31.4 6.4 19.4 34.4 27.0 19.8 45.3 59.5 14.5 84.7 66.2 24.4 70.2 40.7 15.7 22.9 1.1 60.2 14.6 44.2 7.4 19.0 1.4 6.7 11.1 3.8 2.7 4.6 4.5 13.1 2.5 3.9 6.0 32.8 9.7 12.7 2.3 5.4 7.0 17.6 18.6 23.9 20.9 18.1 21.1 22.7 22.9 23.2 19.6 19.8 24.1 24.3 6.4 3.2 70.2 4.1 5.6 5.8 6.9 8.0 8.0 18.2 8.4 5.2 8.6 13.2 14.7 0.0 14.4 3.7 38.5 123.3 21.6 2.9 11.8 23.6 17.8 9.6 11.8 77.4 17.8 19.5 10.6 10.2 31.2 2.5 6.8 23.6 10.7 11.6 10.1 97.9 23.8 10.2 9.6 5.3 5.2 5.6 9.1 14.2 69.3 9.2 17.1 5.2 71.4 46.4 11.7 22.1 10.1 2.6 4.4 58.4 19.0 4.0 3.6 6.6 19.1 15.7 17.1 23.6 8.7 6.1 17.1 5.8 6.2 26.9 4.8 ANTXR1 "ATR, FLJ10601, FLJ21776, TEM8" ENSG00000169604 "ANTXR cell adhesion molecule 1" Q9H6X2 2 69013176-69249327 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor Hypotrichosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 130.6;Endometrial stromal cells: 78.1;Oligodendrocyte precursor cells: 141.8;Skeletal myocytes: 111.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 367.9;TIME: 240.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054785 Uncertain Vesicles "Intracellular and membrane" NA NA 11000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA054785: " "unprognostic (1.44e-1)" "prognostic unfavorable (5.76e-4)" "unprognostic (8.49e-2)" "unprognostic (4.77e-2)" "unprognostic (3.61e-1)" "unprognostic (4.34e-2)" "unprognostic (1.05e-1)" "unprognostic (6.93e-2)" "unprognostic (1.37e-1)" "unprognostic (4.15e-3)" "unprognostic (9.05e-3)" "unprognostic (1.15e-1)" "unprognostic (3.48e-3)" "unprognostic (2.26e-3)" "unprognostic (9.84e-2)" "prognostic unfavorable (1.22e-5)" "unprognostic (2.09e-2)" 38.7 63.1 25.7 20.3 24.1 0.2 32.7 26.6 16.1 77.8 70.2 32.7 12.9 81.4 25.2 33.9 44.1 114.6 39.9 27.9 69.2 11.0 8.2 44.8 12.1 42.5 49.5 107.2 6.7 35.4 14.6 78.8 45.6 47.9 21.4 9.5 28.6 55.4 11.3 39.3 20.2 62.1 36.5 28.3 14.5 11.7 38.3 10.5 43.3 24.0 13.0 52.3 42.4 36.6 36.8 39.5 36.4 33.9 162.7 78.8 0.6 57.1 115.6 63.2 51.5 0.4 3.0 0.0 31.6 147.4 41.7 31.7 30.7 33.8 59.9 0.1 24.4 9.5 90.5 11.9 71.1 7.6 5.1 129.7 13.4 55.5 36.4 140.9 17.3 19.4 6.7 0.1 367.9 15.2 22.1 0.5 35.8 0.0 26.5 0.1 186.3 0.6 13.8 27.9 21.1 91.0 104.3 0.5 37.5 23.7 11.0 2.3 240.4 71.3 61.6 72.1 59.6 0.2 0.1 0.2 37.3 6.7 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 25.7 24.1 26.6 16.1 27.9 69.2 42.5 49.5 45.6 36.5 38.3 36.6 4.7 6.4 20.0 130.6 0.0 49.5 21.1 15.4 17.6 1.7 7.9 13.8 6.8 0.0 8.3 0.0 0.0 0.7 0.1 0.0 0.0 1.5 37.9 5.5 78.1 4.3 0.0 0.0 61.9 2.6 1.9 68.2 0.0 11.7 1.3 22.1 3.3 0.1 4.0 0.0 64.3 0.0 4.1 0.8 19.8 33.9 42.6 2.9 24.9 40.3 0.6 13.6 0.0 141.8 1.3 1.1 0.0 67.7 1.2 10.1 0.0 0.1 9.9 0.8 19.7 111.7 59.6 5.2 2.7 4.6 23.4 1.4 1.7 26.4 0.0 8.9 ANXA10 ANX14 ENSG00000109511 "Annexin A10" Q9UJ72 4 168092537-168187736 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "stomach 1: 486.3" "Group enriched" "Detected in some" 5 "Exocrine glandular cells: 172.6;Gastric mucus-secreting cells: 667.7;Pancreatic endocrine cells: 315.0" "Group enriched" "Detected in many" 5 "pancreatic cancer: 62.4;stomach cancer: 42.2;urothelial cancer: 19.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "OE19: 284.8;PC-3: 125.5;RT4: 172.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005469, HPA074650" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Nucleoli" Vesicles "HPA005469: AB_1844849, HPA074650: " "unprognostic (2.29e-2)" "unprognostic (8.71e-3)" "unprognostic (2.48e-2)" "unprognostic (1.71e-1)" "unprognostic (4.69e-1)" "unprognostic (2.29e-2)" "prognostic favorable (3.64e-6)" "unprognostic (1.18e-3)" "unprognostic (2.88e-1)" "unprognostic (8.61e-4)" "unprognostic (3.43e-2)" "unprognostic (1.84e-1)" "unprognostic (1.69e-3)" "unprognostic (8.41e-2)" "unprognostic (4.01e-1)" "unprognostic (2.04e-1)" "unprognostic (8.89e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 19.6 0.0 0.0 0.3 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 486.3 0.9 0.0 0.0 0.0 0.0 0.0 89.6 0.1 0.0 0.0 4.6 0.0 0.0 0.3 0.1 0.0 0.1 0.2 0.6 0.5 0.0 0.1 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.4 0.0 0.0 0.0 22.5 0.0 0.0 0.0 0.0 0.4 0.1 9.7 0.0 4.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 284.8 125.5 0.0 0.6 0.0 0.0 172.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 7.3 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.5 0.0 1.5 0.0 0.5 15.5 0.0 0.4 0.1 0.0 0.2 7.2 3.2 0.0 2.1 0.0 0.0 0.1 0.0 21.1 11.0 0.1 0.1 0.3 0.0 2.7 0.2 172.6 0.0 0.4 667.7 0.1 0.0 0.0 1.8 72.6 0.0 0.0 0.2 0.5 0.0 2.8 0.0 0.8 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.5 0.0 315.0 1.1 0.0 1.4 0.6 0.0 0.2 0.3 0.6 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.1 14.7 AOAH ENSG00000136250 "Acyloxyacyl hydrolase" P28039 7 36512941-36724549 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.3;lymphoid tissue: 64.9" "Cell type enhanced" "Detected in many" "dendritic cells: 77.9;Kupffer cells: 119.7;Macrophages: 77.1;Microglial cells: 233.3;monocytes: 67.5;NK-cells: 90.6;T-cells: 54.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 298.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "GAMG: 4.8;NB-4: 26.5;THP-1: 20.2;U-937: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA021666, HPA026716" Approved Uncertain Vesicles "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA021666: AB_2670799, HPA026716: AB_2671960" "unprognostic (3.55e-2)" "unprognostic (4.03e-3)" "unprognostic (4.45e-2)" "unprognostic (3.58e-1)" "unprognostic (6.06e-2)" "unprognostic (4.78e-2)" "unprognostic (2.40e-1)" "unprognostic (3.14e-3)" "unprognostic (5.42e-2)" "unprognostic (6.02e-2)" "unprognostic (3.36e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-3)" "unprognostic (1.75e-1)" "unprognostic (1.92e-3)" "unprognostic (2.38e-1)" "unprognostic (1.35e-1)" 7.5 5.1 2.4 33.7 2.2 43.3 3.8 2.1 3.1 5.7 4.7 10.4 9.5 2.8 1.5 3.3 3.5 15.6 2.0 2.1 3.6 1.9 13.2 12.7 35.1 6.6 5.1 2.6 1.5 1.5 0.9 11.2 5.7 2.5 13.3 0.8 3.7 2.8 0.5 0.8 12.1 9.3 4.0 64.9 7.0 1.3 5.1 13.9 1.8 0.9 15.1 13.9 1.3 8.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.6 0.0 0.0 0.0 3.8 0.0 0.3 0.1 0.0 0.0 2.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.6 26.5 0.1 0.0 0.0 0.5 0.0 0.3 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 8.9 0.0 1.8 298.5 97.8 43.6 251.9 9.0 2.6 2.2 30.7 183.1 0.3 4.8 37.3 97.9 106.8 113.2 2.7 0.7 207.3 2.4 2.2 2.1 3.1 2.1 3.6 6.6 5.1 5.7 4.0 5.1 8.6 1.3 0.0 9.6 1.3 3.6 0.8 0.1 0.0 0.0 1.1 0.6 1.7 0.5 1.5 2.5 0.0 0.0 0.2 77.9 9.2 1.9 0.3 0.6 0.4 0.3 1.4 15.5 16.0 12.4 0.0 0.2 3.1 2.6 0.4 5.1 0.7 2.5 0.9 32.8 0.0 8.1 0.3 0.0 119.7 20.3 1.2 0.0 77.1 0.0 233.3 67.5 2.8 90.6 12.1 38.6 0.0 3.8 0.4 13.6 0.1 0.3 0.5 0.7 0.3 0.0 0.3 0.5 0.0 0.1 0.4 0.3 0.1 54.1 0.6 0.9 0.2 AP1B1 "ADTB1, AP105A, BAM22, CLAPB2" ENSG00000100280 "Adaptor related protein complex 1 subunit beta 1" Q10567 22 29327680-29388583 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Deafness, Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 138.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065226, HPA068520" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA 660000 "Cluster 39: Non-specific - mRNA processing" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" "Vesicles, Cytosol" "HPA065226: AB_2685438, HPA068520: AB_2685998" "unprognostic (1.78e-1)" "prognostic favorable (4.81e-4)" "unprognostic (2.40e-1)" "unprognostic (2.21e-2)" "unprognostic (2.37e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (5.55e-5)" "unprognostic (4.99e-2)" "unprognostic (1.59e-1)" "unprognostic (1.27e-1)" "unprognostic (4.98e-3)" "unprognostic (1.60e-1)" "prognostic favorable (7.24e-6)" "unprognostic (1.85e-2)" "unprognostic (3.78e-2)" "unprognostic (2.94e-2)" "unprognostic (3.76e-2)" 30.7 46.7 38.0 47.2 38.3 45.8 26.4 37.3 45.2 22.8 35.6 34.9 43.3 22.7 12.1 63.0 23.5 30.4 23.9 36.1 40.8 34.8 34.8 30.1 57.8 44.2 44.6 17.5 38.3 67.0 39.2 44.8 43.7 38.3 30.1 35.3 40.3 25.9 24.5 47.2 45.6 27.1 41.4 52.6 40.9 24.7 52.7 34.2 29.6 20.5 54.4 39.4 32.2 48.8 84.6 47.5 49.3 50.2 37.0 27.0 60.0 59.8 65.5 71.2 68.2 74.4 33.2 46.1 37.2 68.4 33.0 74.6 71.5 97.6 45.2 58.2 102.0 79.1 60.8 42.0 38.9 114.1 99.9 38.6 36.0 67.5 55.0 33.0 98.7 17.2 54.6 54.9 48.3 93.7 45.5 36.8 37.3 124.8 53.3 89.0 54.3 119.9 50.2 194.5 75.9 52.2 74.0 82.5 36.4 33.5 66.7 49.5 84.6 79.1 48.8 46.0 62.1 60.4 32.5 84.6 56.1 48.1 46.7 0.0 29.3 5.7 9.2 29.2 9.1 16.2 6.3 7.9 28.7 18.2 4.9 5.2 3.0 7.2 31.7 9.0 8.8 24.2 38.0 38.3 37.3 45.2 36.1 40.8 44.2 44.6 43.7 41.4 52.7 48.8 17.8 12.8 16.4 27.7 53.0 7.1 9.3 16.7 16.5 26.3 26.2 20.8 16.1 21.5 16.4 22.0 39.6 52.3 15.1 69.6 23.5 41.2 7.5 16.4 11.6 19.8 21.6 40.0 24.1 40.7 30.1 12.1 33.6 30.1 5.1 13.2 35.3 34.3 138.9 45.4 25.6 24.9 18.3 95.5 24.2 13.1 11.8 65.7 12.4 51.5 29.8 28.4 9.2 16.1 14.0 65.9 33.2 12.4 28.5 17.5 51.2 30.1 14.5 42.1 6.6 17.8 12.7 23.5 17.6 33.0 9.1 68.3 17.0 39.6 36.2 18.1 AP1G1 "ADTG, CLAPG1" ENSG00000166747 "Adaptor related protein complex 1 subunit gamma 1" O43747 16 71729000-71809201 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 268.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009049, HPA041224" Approved Enhanced Vesicles,Cytosol NA NA 62000 "Cluster 49: Eosinophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles Cytosol "CAB009049: AB_2058329, HPA041224: AB_2677370" "unprognostic (4.84e-2)" "unprognostic (5.07e-2)" "unprognostic (2.65e-2)" "unprognostic (2.91e-1)" "unprognostic (1.75e-1)" "unprognostic (2.22e-1)" "unprognostic (1.01e-1)" "unprognostic (8.90e-2)" "unprognostic (9.16e-2)" "unprognostic (2.72e-1)" "unprognostic (2.22e-2)" "unprognostic (4.30e-2)" "prognostic favorable (2.96e-8)" "unprognostic (1.27e-1)" "unprognostic (2.04e-1)" "unprognostic (5.68e-2)" "unprognostic (1.75e-1)" 19.0 25.7 15.4 23.4 16.4 76.7 24.8 19.6 20.8 20.3 26.9 23.6 22.6 17.8 25.5 26.7 18.0 18.9 13.6 16.8 14.9 36.4 33.2 21.4 24.6 14.4 14.5 15.3 24.2 40.4 16.8 17.5 15.8 22.5 25.7 52.8 22.6 16.3 28.2 26.6 23.6 16.1 13.5 22.4 29.3 30.7 15.6 24.9 24.0 36.5 30.4 20.6 18.4 24.3 43.9 62.4 46.3 48.1 48.2 45.4 41.0 44.6 42.1 56.8 54.5 64.3 47.1 55.0 41.9 60.4 41.5 55.4 62.7 49.3 74.4 21.6 33.8 36.2 31.7 46.5 28.9 44.7 114.1 39.1 33.4 76.0 46.9 36.1 50.2 35.8 47.8 23.0 56.1 80.0 39.2 35.3 43.7 34.6 26.8 62.9 37.3 59.3 53.7 49.3 42.5 25.5 55.7 34.8 24.5 46.6 61.0 33.7 60.2 49.4 37.9 27.3 32.9 35.1 50.2 109.2 40.3 34.4 43.3 5.7 6.9 10.0 6.7 7.6 6.8 5.4 5.9 7.5 7.5 5.7 4.6 5.8 14.9 6.7 6.4 5.2 6.6 4.2 15.4 16.4 19.6 20.8 16.8 14.9 14.4 14.5 15.8 13.5 15.6 24.3 32.6 32.1 31.1 42.4 34.2 28.8 27.4 17.3 22.8 26.8 47.6 25.4 13.4 35.8 25.2 36.8 73.0 14.4 40.6 39.3 19.6 21.1 268.8 55.8 37.9 26.0 23.4 9.9 54.2 21.8 13.3 24.0 46.4 84.8 21.0 26.2 21.4 58.5 16.7 30.3 59.0 25.7 12.2 30.4 27.2 130.7 17.7 32.4 23.2 36.5 25.1 16.4 24.7 53.8 79.2 30.5 24.2 19.9 30.6 36.9 30.5 46.4 31.7 66.6 19.7 33.0 26.4 35.8 37.1 32.4 38.6 24.5 33.4 23.0 26.4 47.8 AP1M2 "AP1-mu2, HSMU1B, mu2" ENSG00000129354 "Adaptor related protein complex 1 subunit mu 2" Q9Y6Q5 19 10572671-10587315 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 162.0;Proximal tubular cells: 373.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 4.3;neutrophil: 7.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 7.6" "Cell line enhanced" "Detected in many" "CACO-2: 172.8;Hep G2: 313.8;MCF7: 268.3;OE19: 156.7;RT4: 164.9;U-2 OS: 166.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA054999 Supported Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA054999: AB_2682666" "unprognostic (8.31e-2)" "unprognostic (2.38e-1)" "unprognostic (1.87e-1)" "prognostic favorable (2.07e-4)" "unprognostic (2.07e-1)" "unprognostic (7.76e-2)" "unprognostic (2.11e-3)" "unprognostic (4.83e-2)" "unprognostic (1.93e-1)" "unprognostic (2.49e-2)" "unprognostic (2.65e-1)" "unprognostic (2.23e-2)" "prognostic favorable (3.73e-6)" "unprognostic (1.80e-2)" "unprognostic (8.10e-2)" "unprognostic (2.05e-2)" "unprognostic (1.06e-1)" 3.4 0.1 0.8 6.4 0.3 0.9 32.9 0.6 0.8 27.1 0.3 67.1 64.0 6.6 61.8 51.9 46.6 22.7 0.4 0.5 0.4 76.3 1.5 19.2 0.4 0.7 0.6 0.3 55.9 62.4 34.8 16.2 0.4 30.8 63.4 0.1 41.5 24.0 0.3 42.1 54.8 3.0 0.3 0.6 59.1 9.6 0.7 4.2 58.8 0.3 9.5 23.4 19.1 0.6 144.2 71.1 0.4 10.4 0.0 0.0 65.0 0.2 0.0 2.3 1.6 172.8 82.1 0.4 64.7 1.2 43.4 97.6 0.1 109.0 3.2 0.6 1.0 6.7 48.5 313.8 1.3 0.3 0.8 0.2 81.6 3.9 0.1 5.0 0.0 0.4 0.3 0.6 1.2 268.3 0.6 1.8 31.4 156.7 0.0 2.4 9.3 0.7 2.7 164.9 67.3 0.2 0.0 120.0 0.6 34.6 123.3 0.4 0.0 0.4 166.7 0.9 2.2 0.4 0.9 1.4 0.2 0.4 0.2 4.3 0.4 2.7 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 7.6 0.0 1.4 0.2 0.0 2.7 0.8 0.3 0.6 0.8 0.5 0.4 0.7 0.6 0.4 0.3 0.7 0.6 0.4 28.9 34.8 0.0 1.9 6.9 19.2 68.9 13.1 0.0 49.3 30.0 0.5 47.1 64.2 86.5 0.0 123.0 0.5 112.2 137.0 141.3 43.4 52.4 5.4 1.7 74.4 0.0 0.3 115.8 101.0 1.5 73.4 57.7 2.5 0.0 0.7 0.0 9.8 0.0 0.2 95.5 97.6 0.8 0.0 19.9 1.5 2.6 3.6 0.0 1.7 0.0 0.0 0.0 0.2 130.2 125.6 0.7 0.0 37.6 162.0 373.6 61.5 0.0 0.0 0.0 6.2 16.9 4.1 39.1 13.1 66.1 2.8 0.0 131.4 48.3 AP1S1 "AP19, CLAPS1, EKV3, SIGMA1A, WUGSC:H_DJ0747G18.2" ENSG00000106367 "Adaptor related protein complex 1 subunit sigma 1" P61966 7 101154456-101161596 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Deafness, Ichthyosis, Mental retardation, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 344.4;Proximal enterocytes: 241.3;Proximal tubular cells: 304.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060945 Supported Supported "Golgi apparatus,Vesicles" NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus, Vesicles" "HPA060945: AB_2684393" "unprognostic (1.98e-2)" "unprognostic (5.41e-3)" "unprognostic (1.02e-1)" "unprognostic (3.34e-2)" "unprognostic (2.98e-3)" "unprognostic (8.70e-3)" "unprognostic (7.06e-3)" "unprognostic (1.12e-1)" "unprognostic (1.76e-1)" "unprognostic (7.79e-2)" "unprognostic (1.34e-1)" "unprognostic (3.75e-2)" "unprognostic (2.81e-2)" "unprognostic (2.14e-2)" "unprognostic (1.74e-1)" "unprognostic (1.49e-1)" "unprognostic (2.75e-1)" 14.4 24.6 72.2 13.9 75.7 5.8 17.2 43.7 82.6 18.3 34.6 28.6 39.0 16.9 17.0 34.2 13.8 12.8 11.8 85.2 59.6 41.2 36.2 14.7 11.9 53.6 51.9 13.5 21.9 22.8 31.0 15.9 53.4 22.2 22.4 14.6 20.3 9.3 6.4 39.2 30.3 12.7 46.1 20.2 22.0 16.4 62.5 19.1 15.2 8.5 13.6 20.1 19.5 62.7 121.0 87.3 63.3 118.4 42.8 70.4 138.2 76.8 51.1 50.8 52.8 47.3 147.5 24.9 127.5 84.6 97.1 59.0 35.3 116.0 45.6 57.0 56.6 16.8 52.0 61.4 54.2 46.8 87.7 79.1 91.0 49.4 20.6 76.7 76.8 54.1 56.7 103.2 129.9 292.1 40.4 107.8 97.8 177.0 188.2 24.9 27.2 54.6 127.8 88.8 47.5 157.7 40.4 121.1 151.4 101.6 50.7 46.8 79.0 74.1 132.3 27.6 55.2 21.4 51.4 48.4 195.2 50.1 152.9 0.5 3.3 0.3 2.3 3.1 2.2 2.6 3.2 2.5 4.6 2.0 1.9 1.8 1.2 1.3 1.8 5.0 3.3 2.4 72.2 75.7 43.7 82.6 85.2 59.6 53.6 51.9 53.4 46.1 62.5 62.7 34.4 6.4 0.0 2.3 17.9 38.7 29.7 173.0 46.7 30.7 54.8 49.0 1.1 45.8 72.9 55.2 8.4 170.7 19.8 88.4 344.4 128.2 2.5 28.8 34.2 36.7 90.3 16.2 21.2 111.7 101.3 27.7 42.8 31.9 5.7 85.3 28.9 43.0 95.2 30.3 10.3 96.5 116.0 24.8 21.6 3.4 35.1 27.3 53.4 7.5 58.0 34.1 17.5 2.5 9.8 183.3 86.1 21.8 17.4 34.9 241.3 304.8 34.9 22.3 19.7 11.4 38.4 13.1 70.9 51.4 45.5 60.5 19.5 157.4 119.9 38.2 AP1S2 "MRX59, MRXS5, PGS, SIGMA1B" ENSG00000182287 "Adaptor related protein complex 1 subunit sigma 2" P56377 X 15825806-15854931 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "epididymis: 663.3" "Cell type enhanced" "Detected in all" "Hofbauer cells: 259.8;Kupffer cells: 392.6;Langerhans cells: 609.2;Macrophages: 362.7;monocytes: 630.0" "Group enriched" "Detected in all" 4 "endometrial cancer: 13.1;glioma: 22.0;melanoma: 49.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 326.8;intermediate monocyte: 325.0;myeloid DC: 221.1;non-classical monocyte: 175.4;plasmacytoid DC: 82.2" "Group enriched" "Detected in all" 5 "dendritic cells: 221.1;monocytes: 326.8" "Cell line enhanced" "Detected in all" "Karpas-707: 298.0;SK-MEL-30: 442.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049894, HPA060945" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Vesicles" "HPA049894: AB_2680939, HPA060945: AB_2684393" "prognostic favorable (9.86e-4)" "unprognostic (4.62e-2)" "unprognostic (2.11e-1)" "unprognostic (1.68e-1)" "unprognostic (2.47e-3)" "unprognostic (3.85e-1)" "unprognostic (2.03e-3)" "unprognostic (5.76e-2)" "unprognostic (1.43e-2)" "prognostic favorable (5.53e-6)" "unprognostic (1.85e-2)" "unprognostic (5.61e-2)" "unprognostic (5.08e-2)" "unprognostic (6.35e-2)" "unprognostic (3.13e-1)" "unprognostic (9.34e-2)" "unprognostic (6.47e-2)" 28.3 21.4 24.6 36.7 28.4 38.3 15.0 32.0 36.9 31.6 27.3 42.1 11.9 52.2 663.3 21.4 13.5 20.1 74.8 25.1 48.0 13.1 15.9 25.8 33.2 42.7 35.8 8.8 7.8 16.7 19.4 42.0 47.0 11.6 22.0 43.7 9.5 30.5 70.1 14.0 20.1 76.3 34.4 43.0 19.5 23.4 29.6 28.7 12.5 93.7 28.8 26.1 12.7 33.8 12.0 14.2 130.1 78.4 29.5 19.1 5.0 47.1 22.7 31.1 41.1 9.6 11.1 22.6 183.0 72.6 50.4 16.1 31.7 10.8 57.0 30.1 64.9 15.3 16.7 14.7 24.2 63.1 16.9 12.2 11.2 36.0 33.1 50.4 78.1 19.1 14.3 298.0 72.4 8.7 12.9 39.5 171.0 6.4 42.5 29.5 116.7 50.6 37.4 2.5 14.8 69.2 18.4 4.8 442.2 84.1 52.7 69.2 43.9 67.8 21.2 92.5 41.9 25.5 58.7 37.3 33.6 28.0 159.7 50.9 326.8 34.6 21.1 325.0 24.8 30.8 25.5 20.6 221.1 28.0 18.5 18.1 52.8 27.9 175.4 82.2 38.1 228.0 24.6 28.4 32.0 36.9 25.1 48.0 42.7 35.8 47.0 34.4 29.6 33.8 130.8 3.2 13.1 37.2 77.0 55.2 12.7 9.1 8.6 34.7 12.0 11.4 195.6 12.8 3.2 9.2 12.5 5.3 114.2 9.2 33.2 13.7 5.1 50.4 32.6 166.3 26.9 32.6 15.1 6.4 18.9 38.0 7.7 78.0 78.6 15.6 147.4 8.6 259.8 11.8 73.2 8.4 12.2 392.6 609.2 17.5 17.4 362.7 149.4 31.9 630.0 21.1 62.8 19.1 85.0 10.3 14.0 7.2 26.0 19.0 6.5 9.0 1.6 39.3 39.5 26.7 39.1 55.7 28.8 10.6 51.6 5.6 58.3 4.0 8.5 6.7 AP1S3 ENSG00000152056 "Adaptor related protein complex 1 subunit sigma 3" Q96PC3 2 223751686-223838027 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 52.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Cytotrophoblasts: 48.2;Pancreatic endocrine cells: 44.2;Urothelial cells: 69.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 4.9;dendritic cells: 4.0;granulocytes: 4.9" "Cell line enhanced" "Detected in many" "CACO-2: 151.1;RPTEC TERT1: 56.8;RT4: 52.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA066782 Approved Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 39: CACO-2 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "HPA066782: AB_2685720" "unprognostic (9.45e-3)" "unprognostic (1.79e-1)" "unprognostic (7.52e-2)" "unprognostic (5.80e-2)" "unprognostic (4.37e-2)" "unprognostic (4.89e-1)" "unprognostic (1.65e-3)" "prognostic unfavorable (3.36e-5)" "unprognostic (1.81e-1)" "unprognostic (1.47e-1)" "prognostic unfavorable (2.08e-5)" "unprognostic (1.56e-1)" "unprognostic (2.33e-1)" "unprognostic (2.50e-2)" "unprognostic (1.90e-1)" "unprognostic (2.32e-2)" "unprognostic (4.61e-2)" 0.7 0.8 3.4 3.3 3.2 4.0 2.1 3.9 3.5 2.2 0.5 2.7 5.3 0.9 52.8 4.8 2.3 5.2 0.5 2.8 3.0 5.6 1.4 4.7 4.2 2.0 1.6 0.5 2.4 3.8 1.1 6.6 1.5 2.9 2.6 5.7 1.6 5.4 0.9 1.9 5.0 0.7 1.1 2.8 9.8 0.9 3.2 1.6 14.4 0.3 5.2 8.1 1.2 2.1 28.7 17.7 2.4 12.0 1.5 0.6 13.5 11.5 2.4 4.9 4.2 151.1 21.8 11.0 8.0 1.7 5.8 43.8 6.4 30.3 6.8 15.3 8.9 1.2 33.7 15.7 0.6 3.4 1.3 0.6 31.2 9.1 30.1 11.2 3.4 5.8 1.8 2.9 2.9 12.3 0.6 0.9 3.8 32.8 15.5 4.3 0.1 4.5 56.8 52.1 7.4 2.1 5.4 11.8 3.8 6.1 5.0 6.3 2.0 1.6 4.6 3.1 9.2 10.2 9.0 28.2 4.4 2.0 6.0 4.9 0.5 0.3 0.6 0.4 0.5 4.9 0.4 0.4 1.2 2.7 0.4 0.5 1.8 0.6 0.2 4.0 1.0 0.4 3.4 3.2 3.9 3.5 2.8 3.0 2.0 1.6 1.5 1.1 3.2 2.1 0.4 35.3 6.7 8.8 24.2 4.2 32.6 15.3 4.0 3.3 4.3 1.8 1.7 0.0 15.8 11.0 64.6 48.2 13.6 3.6 9.8 17.5 0.2 8.1 2.1 2.1 2.4 0.0 19.3 18.1 3.4 3.5 11.7 26.1 3.8 0.8 0.7 0.4 4.7 6.7 9.6 3.6 16.2 1.6 38.1 0.0 0.3 7.5 3.6 4.7 7.4 1.9 6.2 10.6 4.0 44.2 4.6 0.0 10.7 26.6 5.4 4.5 10.3 5.9 0.0 1.1 1.8 0.3 1.9 6.3 4.1 13.1 6.9 1.0 4.7 69.6 AP2A1 "ADTAA, CLAPA1" ENSG00000196961 "Adaptor related protein complex 2 subunit alpha 1" O95782 19 49767001-49807114 "Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 165.0;Syncytiotrophoblasts: 241.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 20.5" "Lineage enriched" "Detected in all" 4 "monocytes: 20.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB004306 Approved Supported Vesicles NA NA 61000 "Cluster 51: Monocytes - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "CAB004306: AB_2274034" "unprognostic (4.33e-2)" "unprognostic (1.52e-1)" "unprognostic (4.61e-1)" "unprognostic (7.18e-2)" "unprognostic (1.88e-1)" "unprognostic (1.23e-1)" "unprognostic (1.92e-2)" "unprognostic (5.85e-3)" "unprognostic (4.84e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (2.82e-2)" "unprognostic (2.38e-2)" "prognostic unfavorable (2.83e-9)" "unprognostic (2.63e-1)" "unprognostic (1.45e-1)" "unprognostic (7.90e-2)" "unprognostic (1.72e-3)" 47.0 87.4 37.4 25.2 47.9 54.4 41.2 20.6 49.2 48.1 9.0 42.2 24.7 56.6 7.4 46.5 48.2 19.6 52.2 44.2 31.8 33.3 51.1 37.2 19.5 45.8 31.4 57.1 33.8 13.9 34.3 31.4 45.3 33.0 9.9 13.9 28.9 18.6 89.6 54.2 34.0 21.4 17.8 47.6 36.3 88.8 50.0 15.4 30.5 26.9 13.2 46.0 43.6 35.8 70.9 100.3 33.8 78.7 59.5 72.2 69.0 82.0 55.3 49.7 51.8 52.0 43.5 31.5 30.6 85.2 41.9 62.8 25.7 59.0 21.1 50.1 58.4 46.6 66.1 56.8 65.3 37.7 75.0 113.6 42.3 55.4 28.7 44.2 59.5 51.3 118.5 42.7 47.6 55.8 41.6 50.2 34.6 66.6 101.8 46.6 79.7 40.4 29.6 88.1 25.7 34.7 90.1 61.1 34.3 36.1 52.1 52.9 82.9 128.4 70.6 54.6 59.3 63.1 83.5 33.1 90.5 54.8 55.1 0.3 5.3 3.4 2.0 12.8 1.4 1.2 1.2 1.2 4.6 1.0 0.9 1.3 4.0 2.3 20.5 1.4 1.6 4.8 37.4 47.9 20.6 49.2 44.2 31.8 45.8 31.4 45.3 17.8 50.0 35.8 22.9 0.0 2.3 19.6 18.5 13.8 19.0 18.5 14.8 45.1 26.7 19.0 2.9 14.3 11.7 14.7 43.8 90.8 21.8 39.1 11.7 16.1 129.9 23.0 57.1 22.4 2.4 106.5 24.2 29.4 35.3 36.0 22.4 16.0 8.9 33.2 39.3 36.6 31.3 50.5 25.5 17.4 8.2 56.2 21.3 165.0 53.4 34.0 19.6 14.0 40.4 31.5 63.8 14.1 21.8 27.3 19.0 61.7 28.1 16.3 41.2 50.4 14.9 30.2 59.2 23.2 28.5 54.7 59.2 22.1 13.9 241.6 23.2 48.6 23.9 24.3 AP2A2 "ADTAB, CLAPA2, DKFZP564D1864, HIP9, HYPJ, KIAA0899" ENSG00000183020 "Adaptor related protein complex 2 subunit alpha 2" O94973 11 924894-1012245 "Plasma proteins, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017514, HPA043040" Supported Supported Nucleoplasm,Vesicles NA NA 10000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoplasm "CAB017514: AB_2056344, HPA043040: AB_2678283" "unprognostic (1.90e-1)" "unprognostic (1.54e-1)" "unprognostic (2.20e-1)" "unprognostic (2.09e-2)" "unprognostic (1.28e-2)" "unprognostic (5.72e-2)" "prognostic unfavorable (9.27e-5)" "unprognostic (1.34e-2)" "unprognostic (4.09e-1)" "unprognostic (1.70e-1)" "prognostic favorable (4.57e-4)" "unprognostic (2.41e-1)" "unprognostic (2.86e-3)" "unprognostic (1.05e-1)" "unprognostic (1.58e-1)" "unprognostic (1.40e-1)" "unprognostic (2.08e-2)" 20.1 18.0 3.5 1.3 5.1 4.5 16.6 10.8 9.9 20.3 1.4 23.0 5.4 17.9 1.5 12.7 18.1 2.0 19.1 5.5 3.5 34.4 29.9 18.9 3.2 0.9 2.1 17.5 25.3 3.7 25.6 5.2 3.0 20.3 4.9 5.8 14.6 4.0 14.1 14.5 19.6 5.6 0.0 57.6 20.6 15.5 3.3 3.8 13.9 1.6 2.5 19.0 15.7 1.4 7.5 2.9 3.7 10.7 13.8 14.2 9.1 10.2 3.3 6.0 4.9 1.3 7.3 7.4 8.7 12.3 5.7 8.9 8.9 5.6 3.9 5.5 23.2 2.1 10.4 3.9 5.3 2.8 4.9 16.8 6.1 3.1 6.1 14.8 8.5 5.0 5.9 4.7 6.3 0.4 2.6 3.2 2.0 9.1 17.9 4.2 2.6 8.1 9.2 6.2 12.3 10.0 11.4 9.2 1.7 6.3 5.4 0.8 13.3 1.9 2.3 2.8 5.2 4.3 3.9 5.3 4.0 3.7 3.1 1.5 1.7 1.5 1.1 1.7 0.5 0.5 1.1 0.6 1.4 1.0 1.1 1.2 2.1 1.1 1.4 1.3 2.1 0.6 3.5 5.1 10.8 9.9 5.5 3.5 0.9 2.1 3.0 0.0 3.3 1.4 38.1 38.5 21.8 29.4 14.3 14.3 12.4 13.3 7.4 50.9 27.2 23.0 12.9 21.5 15.9 62.5 60.5 42.1 17.3 45.3 39.2 37.5 46.7 64.0 44.6 36.6 35.2 27.1 37.2 18.0 45.2 28.7 16.3 86.7 27.3 31.0 80.3 59.8 82.8 101.0 36.4 32.3 18.3 104.7 26.9 28.3 34.5 51.8 8.8 41.2 31.2 30.4 39.1 23.1 21.9 25.8 24.2 27.8 13.6 16.9 43.5 70.4 23.5 69.2 26.3 20.7 22.6 72.7 28.0 11.2 11.4 28.5 19.7 30.5 37.0 11.5 AP2B1 "ADTB2, CLAPB1" ENSG00000006125 "Adaptor related protein complex 2 subunit beta 1" P63010 17 35578046-35726413 "Cancer-related genes, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 503.9;Late spermatids: 739.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017631, HPA056733, HPA067983" Approved Supported Vesicles NA NA 380000 "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "CAB017631: AB_2058201, HPA056733: AB_2683219, HPA067983: AB_2732777" "unprognostic (1.49e-2)" "unprognostic (4.04e-3)" "unprognostic (2.15e-3)" "unprognostic (1.48e-1)" "unprognostic (1.16e-1)" "unprognostic (3.01e-2)" "unprognostic (1.51e-3)" "unprognostic (2.64e-2)" "unprognostic (1.06e-1)" "unprognostic (4.73e-2)" "unprognostic (2.58e-2)" "unprognostic (2.50e-1)" "prognostic favorable (2.62e-4)" "unprognostic (1.70e-1)" "unprognostic (1.10e-1)" "unprognostic (3.25e-2)" "unprognostic (1.57e-2)" 46.4 42.4 77.0 38.2 87.8 49.2 58.3 69.9 88.7 54.1 76.6 67.6 33.5 41.7 70.7 25.1 46.7 42.3 67.6 92.1 83.5 69.0 35.0 53.4 38.6 69.8 78.6 57.2 33.2 126.4 55.0 66.8 76.8 40.9 84.0 76.1 41.9 50.1 57.5 29.9 38.8 56.0 80.3 42.0 48.4 93.5 78.7 59.7 65.1 61.0 45.5 46.8 34.4 95.0 188.8 233.9 113.7 132.0 184.4 202.8 51.6 94.3 138.9 131.0 141.1 129.0 154.6 90.5 81.1 175.3 168.8 173.2 162.5 264.8 190.8 108.6 147.0 117.7 161.8 71.0 104.7 119.3 80.8 128.9 104.3 134.5 209.3 151.2 211.4 111.8 190.6 126.9 206.9 36.9 113.7 58.7 94.2 98.9 164.5 94.3 165.1 64.7 166.2 108.3 94.4 114.1 114.5 39.6 126.9 273.3 161.5 78.5 211.5 99.3 93.4 109.8 142.1 53.0 106.1 84.7 124.1 86.9 112.5 19.6 11.8 16.7 16.0 15.3 16.9 12.1 13.9 14.3 10.7 11.9 6.3 8.0 13.3 9.6 16.8 10.7 20.5 11.0 77.0 87.8 69.9 88.7 92.1 83.5 69.8 78.6 76.8 80.3 78.7 95.0 76.5 16.0 17.0 49.3 45.9 31.1 26.3 57.4 70.6 67.6 88.9 50.9 62.5 68.6 37.4 112.2 56.3 29.7 70.7 97.4 117.4 105.0 503.9 74.5 83.7 56.8 71.3 214.7 105.5 120.2 42.8 47.1 36.2 85.4 41.2 46.5 79.9 64.5 44.1 69.0 109.8 79.4 28.5 54.3 25.9 739.2 58.7 37.2 16.0 60.0 47.3 52.6 74.2 81.4 89.0 177.9 46.6 68.4 32.1 37.4 39.4 102.5 30.4 40.9 59.2 25.3 37.6 258.8 60.0 19.6 14.6 32.8 49.2 37.3 89.8 29.1 AP3S1 CLAPS3 ENSG00000177879 "Adaptor related protein complex 3 subunit sigma 1" Q92572 5 115841592-115914081 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049270 Uncertain Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA049270: AB_2680696" "prognostic unfavorable (1.22e-4)" "unprognostic (2.54e-2)" "unprognostic (8.05e-2)" "unprognostic (1.68e-2)" "prognostic unfavorable (3.33e-4)" "unprognostic (2.60e-2)" "unprognostic (3.83e-3)" "unprognostic (4.42e-3)" "unprognostic (1.36e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (1.13e-5)" "unprognostic (1.73e-1)" "prognostic unfavorable (9.57e-8)" "unprognostic (2.73e-2)" "unprognostic (3.62e-2)" "unprognostic (2.75e-1)" "unprognostic (1.64e-1)" 63.1 44.5 57.0 38.7 59.7 133.3 60.1 55.2 84.5 70.1 54.6 53.7 61.9 55.1 113.6 65.8 46.1 49.2 52.6 61.5 60.7 37.4 74.7 38.1 64.6 62.3 60.3 69.6 63.2 24.9 19.7 60.1 62.8 43.6 60.1 34.0 59.4 85.6 21.9 60.7 81.5 64.1 59.1 39.0 37.7 57.3 58.4 41.1 49.3 34.4 61.1 60.2 25.4 59.5 134.3 44.8 95.2 63.4 257.4 369.1 89.2 142.6 132.4 94.1 152.0 98.9 121.4 107.5 68.4 162.8 115.4 38.1 58.8 230.4 157.6 320.3 114.4 45.1 43.8 146.2 139.8 76.2 84.6 168.6 177.9 100.2 112.1 123.5 109.4 122.1 47.1 80.9 150.3 49.9 87.3 129.0 71.1 65.5 74.4 85.0 141.9 172.0 123.2 58.8 35.1 53.8 222.8 42.7 146.3 86.2 70.3 116.1 115.4 173.1 116.5 127.1 113.4 71.6 47.3 91.8 129.9 144.2 73.5 81.9 70.7 174.8 37.6 79.2 63.7 67.1 47.1 52.3 54.5 47.3 39.9 41.6 110.0 48.3 75.8 94.8 60.3 70.6 57.0 59.7 55.2 84.5 61.5 60.7 62.3 60.3 62.8 59.1 58.4 59.5 75.6 22.4 21.9 31.3 90.1 203.0 92.8 308.5 95.0 68.0 72.9 59.3 26.4 67.2 115.0 46.0 25.0 74.1 95.0 129.7 70.5 93.6 130.2 37.8 62.1 73.9 76.1 31.7 83.1 86.5 309.4 158.3 43.8 35.1 83.6 39.6 81.8 87.2 152.6 26.9 61.2 131.5 105.8 111.7 185.7 217.4 173.1 88.4 115.6 68.4 103.9 19.6 74.2 46.3 49.9 111.4 105.5 111.3 103.6 118.3 361.1 156.7 59.8 77.7 32.9 48.2 118.0 108.8 104.7 131.5 227.9 128.7 79.0 60.7 74.9 112.5 AP3S2 sigma3b ENSG00000157823 "Adaptor related protein complex 3 subunit sigma 2" P59780 15 89830599-89894638 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049270 Uncertain Approved Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA049270: AB_2680696" "unprognostic (1.46e-1)" "unprognostic (1.60e-2)" "unprognostic (1.18e-2)" "unprognostic (1.12e-1)" "unprognostic (2.28e-1)" "unprognostic (2.68e-1)" "unprognostic (3.78e-2)" "unprognostic (5.27e-2)" "unprognostic (3.03e-1)" "unprognostic (7.59e-2)" "unprognostic (1.22e-1)" "unprognostic (4.31e-2)" "prognostic favorable (5.55e-16)" "unprognostic (7.97e-2)" "unprognostic (1.13e-1)" "unprognostic (2.43e-1)" "unprognostic (8.67e-3)" 24.2 20.3 15.1 11.2 15.8 10.4 19.4 14.9 18.1 17.3 13.3 19.3 10.9 13.0 16.3 20.7 17.3 17.5 30.7 15.0 17.0 36.5 40.5 16.3 12.9 16.0 18.4 20.0 19.0 32.6 9.0 18.5 18.4 15.3 19.2 44.0 13.5 21.4 44.8 8.7 10.2 18.0 15.0 12.6 10.0 12.5 16.7 20.1 26.2 45.2 17.7 15.3 6.8 16.7 13.5 60.6 33.4 35.6 66.7 45.6 28.0 58.8 75.2 74.3 59.7 26.0 34.8 12.1 51.3 39.1 48.9 31.0 57.4 33.1 58.3 51.2 29.0 37.3 25.4 33.6 28.1 16.1 22.3 30.9 40.4 20.7 41.6 40.6 38.8 30.8 29.1 32.8 48.0 27.7 27.6 8.7 37.2 68.5 11.6 15.9 33.8 25.0 42.1 35.9 25.5 22.3 69.4 43.1 40.4 69.8 26.9 14.1 16.3 40.0 19.2 62.1 19.6 28.3 94.5 28.9 35.8 18.7 24.1 6.3 16.6 7.8 5.0 15.4 7.8 4.5 7.2 7.4 11.6 6.3 5.7 4.0 16.1 8.3 19.9 7.4 8.4 10.6 15.1 15.8 14.9 18.1 15.0 17.0 16.0 18.4 18.4 15.0 16.7 16.7 5.9 12.8 15.4 0.0 5.9 3.3 4.0 6.0 5.2 22.0 8.0 5.7 18.2 10.0 11.2 5.5 35.5 8.9 6.1 34.4 9.8 13.4 3.1 5.9 10.8 7.2 14.4 5.0 0.0 16.1 4.2 9.0 8.2 7.1 8.2 15.4 8.9 17.0 6.4 18.5 0.0 11.4 2.0 12.0 6.4 3.2 7.2 9.7 8.8 0.0 16.9 17.3 9.2 0.0 0.0 13.4 16.4 7.5 8.6 5.8 15.8 13.7 9.8 30.6 0.0 6.1 6.0 11.6 8.3 6.1 2.8 6.4 6.2 28.5 15.2 4.2 AP4B1 "BETA-4, SPG47" ENSG00000134262 "Adaptor related protein complex 4 subunit beta 1" Q9Y6B7 1 113894194-113905201 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 65.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028162, HPA028652" Approved Approved Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Transcription" Vesicles "HPA028162: AB_10610976, HPA028652: AB_10601451" "unprognostic (8.90e-2)" "unprognostic (2.25e-2)" "unprognostic (1.77e-1)" "unprognostic (2.40e-2)" "unprognostic (1.53e-1)" "unprognostic (5.01e-2)" "prognostic unfavorable (8.60e-7)" "unprognostic (3.45e-2)" "unprognostic (1.54e-2)" "unprognostic (8.34e-3)" "unprognostic (1.55e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (3.73e-6)" "unprognostic (5.08e-3)" "unprognostic (7.88e-2)" "unprognostic (3.12e-1)" "unprognostic (1.55e-2)" 9.7 8.5 12.5 11.1 13.1 20.5 9.3 14.6 14.6 11.9 10.9 11.5 10.6 9.7 14.2 12.1 11.0 7.0 11.2 13.0 13.0 9.7 8.4 9.5 14.3 11.6 11.4 13.7 14.0 4.8 13.7 5.9 11.8 9.6 12.7 20.0 7.6 6.2 11.7 11.5 12.8 9.1 11.5 20.1 10.4 11.1 13.3 16.1 11.0 9.1 13.9 9.2 10.0 13.3 11.0 9.8 10.0 11.8 15.7 14.1 6.4 10.1 9.8 13.0 14.0 6.8 7.7 21.5 15.9 12.4 6.5 9.7 11.3 13.4 16.5 16.6 9.8 17.6 13.6 8.3 9.5 19.6 17.3 16.1 6.7 25.5 15.3 7.8 22.7 20.9 12.3 18.5 17.6 65.2 15.6 21.6 9.4 7.7 19.0 15.0 19.5 13.3 13.2 5.5 10.2 8.5 10.1 19.1 7.8 9.5 5.7 15.4 21.8 15.0 13.9 17.4 20.8 15.2 15.8 21.3 24.6 26.0 25.1 15.9 10.5 8.6 14.7 10.8 15.6 9.5 11.7 12.6 12.9 11.9 12.7 11.1 1.2 12.2 8.5 9.1 10.4 9.5 12.5 13.1 14.6 14.6 13.0 13.0 11.6 11.4 11.8 11.5 13.3 13.3 7.2 3.2 6.7 7.5 12.3 3.6 3.3 5.4 4.6 6.8 3.2 4.3 8.7 5.7 11.9 3.7 31.3 3.8 12.0 7.8 1.9 7.7 3.6 4.6 4.7 7.6 3.0 18.1 11.4 26.8 3.5 7.0 11.2 5.2 2.5 4.5 7.5 4.1 5.2 8.4 11.6 5.3 6.1 7.3 4.9 2.3 2.8 6.9 7.2 7.5 6.1 4.7 3.1 11.6 10.0 10.9 6.9 4.9 7.4 2.8 6.5 3.3 5.2 21.0 13.1 6.1 6.2 16.4 11.5 5.7 3.7 1.6 14.8 6.4 9.0 3.3 AP4S1 "AP47B, CLA20, SPG52" ENSG00000100478 "Adaptor related protein complex 4 subunit sigma 1" Q9Y587 14 31025106-31130996 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 36.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039963 Approved Supported Vesicles NA NA "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA039963: AB_10795240" "unprognostic (4.03e-2)" "unprognostic (1.42e-1)" "unprognostic (1.65e-1)" "unprognostic (2.43e-1)" "unprognostic (1.14e-1)" "unprognostic (8.00e-3)" "unprognostic (1.03e-1)" "prognostic favorable (7.44e-4)" "unprognostic (3.79e-2)" "unprognostic (8.62e-3)" "unprognostic (1.15e-2)" "unprognostic (3.02e-1)" "prognostic favorable (2.87e-6)" "unprognostic (2.20e-3)" "unprognostic (5.44e-2)" "unprognostic (7.75e-2)" "unprognostic (5.59e-2)" 4.8 6.3 9.8 6.6 10.6 6.0 5.7 14.1 12.8 6.5 5.6 8.6 3.9 7.7 7.0 4.9 7.3 5.4 8.7 9.5 10.2 7.8 6.2 5.4 8.1 6.3 6.5 10.7 7.9 6.5 8.5 6.7 6.1 6.2 4.1 11.9 5.2 6.7 12.6 4.6 4.4 7.9 5.4 8.0 4.3 18.4 9.0 6.6 8.8 7.2 7.7 6.2 4.8 10.1 9.0 12.6 11.0 3.2 4.4 7.9 8.5 6.0 10.4 9.6 9.5 12.2 14.5 10.6 5.5 7.3 7.2 9.7 7.6 9.4 15.9 9.1 4.4 16.4 5.5 19.0 9.5 14.1 9.2 6.3 5.9 9.6 12.0 6.4 11.7 8.0 8.4 7.0 10.3 12.5 9.7 7.8 13.1 10.5 10.9 10.3 9.8 1.4 10.5 12.4 6.1 6.1 10.7 5.1 16.3 7.3 10.8 6.5 8.8 7.3 6.5 5.0 5.2 8.6 17.0 15.9 4.2 4.4 5.7 3.4 1.3 2.4 2.5 3.5 3.7 3.3 3.8 3.0 1.2 3.4 3.7 4.5 2.6 5.8 2.8 3.3 6.6 1.7 9.8 10.6 14.1 12.8 9.5 10.2 6.3 6.5 6.1 5.4 9.0 10.1 7.1 9.6 7.7 10.7 8.1 3.4 6.5 6.5 1.2 12.1 4.0 4.3 16.5 4.3 3.1 5.5 31.3 9.1 7.6 3.9 5.9 7.6 21.9 5.2 8.8 6.7 6.0 3.8 29.4 4.8 5.3 6.2 7.1 5.8 7.6 7.8 10.8 4.0 7.4 6.7 24.9 3.8 4.1 5.4 4.1 17.0 6.8 6.0 3.6 12.2 7.5 9.3 5.2 25.1 16.4 2.8 6.2 8.6 4.2 4.0 5.0 7.7 8.1 24.4 6.6 8.5 8.1 36.0 8.3 3.0 2.8 11.5 7.3 8.2 4.0 5.2 AP5B1 "AP-5, DKFZp761E198, PP1030" ENSG00000254470 "Adaptor related protein complex 5 subunit beta 1" Q2VPB7 11 65773898-65780976 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "bone marrow: 44.0" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 34.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 14 "neutrophil: 25.0" "Lineage enriched" "Detected in many" 14 "granulocytes: 25.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065739, HPA067880" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "Golgi apparatus" "HPA065739: AB_2685550, HPA067880: AB_2685914" "unprognostic (3.64e-1)" "unprognostic (9.40e-2)" "unprognostic (4.37e-3)" "unprognostic (1.45e-2)" "unprognostic (5.56e-3)" "unprognostic (1.09e-2)" "unprognostic (1.29e-2)" "unprognostic (3.26e-2)" "unprognostic (1.73e-1)" "unprognostic (1.62e-2)" "unprognostic (1.25e-1)" "unprognostic (2.15e-1)" "prognostic favorable (2.31e-5)" "unprognostic (2.03e-2)" "unprognostic (2.15e-2)" "unprognostic (2.45e-1)" "unprognostic (1.67e-1)" 8.3 4.8 3.2 6.9 2.6 44.0 6.6 5.8 3.6 5.4 1.3 6.0 5.7 7.1 2.0 10.2 5.2 3.1 5.0 3.6 1.2 5.7 5.8 8.7 4.7 3.9 1.5 2.9 10.3 6.4 3.5 3.8 3.0 5.0 3.0 2.5 7.0 4.5 9.6 9.1 6.8 3.2 1.1 10.0 6.0 2.5 1.8 4.8 4.9 3.4 4.3 6.6 5.1 1.6 12.8 9.8 2.8 14.3 8.6 4.1 16.4 5.3 6.2 6.1 4.7 7.7 6.0 7.8 9.4 6.3 12.4 15.8 8.7 4.3 2.9 12.1 10.1 7.0 12.0 3.8 5.8 9.9 13.3 7.0 10.1 4.0 2.9 6.0 5.2 13.6 15.6 9.7 3.6 9.2 5.5 10.5 4.6 4.4 10.1 17.3 0.5 16.8 5.9 15.8 2.7 5.4 4.1 2.6 26.0 3.7 4.4 14.1 7.6 10.2 8.6 13.6 6.0 10.0 11.2 8.1 7.5 8.5 10.5 1.1 1.7 0.6 0.5 1.0 0.2 0.3 0.2 0.2 0.5 0.3 0.3 0.2 25.0 0.4 1.3 0.3 0.2 0.8 3.2 2.6 5.8 3.6 3.6 1.2 3.9 1.5 3.0 1.1 1.8 1.6 2.0 0.0 8.8 6.2 3.9 2.4 12.3 4.3 7.4 5.0 4.2 2.0 1.6 2.8 3.7 7.3 14.6 7.6 5.9 12.8 1.9 8.9 1.4 6.3 2.9 3.0 3.0 0.0 3.6 13.6 18.2 2.9 6.6 10.7 2.5 5.3 1.4 7.1 14.0 11.8 3.2 3.8 6.1 12.4 2.1 0.7 0.6 11.6 7.2 3.7 17.8 3.0 6.2 1.0 2.2 9.4 6.9 3.8 3.6 5.6 10.1 8.8 2.9 8.0 0.0 3.7 3.0 0.6 4.7 6.0 2.3 34.9 4.3 2.0 4.5 10.0 APBA3 "mint3, X11L2" ENSG00000011132 "Amyloid beta precursor protein binding family A member 3" O96018 19 3750772-3761692 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045577 Approved Approved Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA045577: AB_10964881" "unprognostic (3.47e-2)" "unprognostic (3.58e-2)" "unprognostic (5.00e-2)" "prognostic favorable (5.97e-4)" "unprognostic (1.69e-1)" "prognostic favorable (4.91e-4)" "unprognostic (6.64e-2)" "unprognostic (7.60e-3)" "unprognostic (1.02e-1)" "unprognostic (3.01e-1)" "prognostic favorable (1.51e-4)" "unprognostic (5.58e-3)" "unprognostic (2.67e-3)" "unprognostic (1.31e-2)" "unprognostic (2.28e-1)" "unprognostic (6.12e-2)" "prognostic favorable (1.83e-4)" 6.7 6.7 3.1 3.5 4.0 2.0 7.1 3.8 5.3 8.0 2.8 8.0 3.5 7.9 0.1 7.5 6.9 1.1 7.6 2.9 3.2 8.3 10.3 6.7 3.7 4.4 3.7 9.4 7.9 1.5 7.1 2.0 4.1 7.5 0.6 0.4 8.4 2.5 15.4 7.5 8.4 1.4 3.4 11.2 8.3 3.2 3.7 2.8 8.3 2.7 1.9 7.5 6.8 5.6 8.0 6.0 1.3 2.3 2.4 1.8 6.4 5.1 3.0 2.7 3.7 5.8 2.7 5.4 4.4 2.0 6.3 3.8 1.4 4.3 0.6 20.5 4.5 3.1 4.9 4.6 8.1 1.9 11.2 3.6 5.3 3.4 2.2 2.2 3.7 5.5 5.2 8.4 1.2 4.7 6.1 7.8 3.5 2.6 8.9 6.3 2.6 8.9 1.9 5.0 4.6 4.8 3.2 4.6 7.9 0.8 2.0 4.6 6.4 4.5 4.6 7.9 6.3 17.0 6.8 4.9 4.1 6.2 4.8 11.3 7.3 11.4 13.0 5.6 11.9 9.5 12.9 12.9 8.3 11.6 8.2 10.0 10.2 6.9 5.1 7.8 19.8 8.4 3.1 4.0 3.8 5.3 2.9 3.2 4.4 3.7 4.1 3.4 3.7 5.6 4.9 6.4 5.6 2.9 12.1 4.2 6.5 18.1 4.0 3.9 7.0 6.2 4.7 4.3 7.9 7.3 8.4 10.6 9.0 8.0 7.9 14.2 0.9 2.9 4.8 6.4 4.8 1.3 3.4 9.0 10.0 7.6 13.3 5.4 2.5 5.4 5.3 8.2 8.6 3.3 3.2 9.1 10.2 6.7 9.3 0.5 6.2 5.9 5.4 1.0 16.4 3.3 13.4 3.0 5.2 12.6 5.8 3.0 13.4 9.3 19.5 11.3 3.8 6.4 6.6 4.0 5.1 2.5 6.2 7.7 7.5 15.3 12.4 3.5 7.5 6.4 APEX2 "APE2, APEXL2, XTH2, ZGRF2" ENSG00000169188 "Apurinic/apyrimidinic endodeoxyribonuclease 2" Q9UBZ4 X 55000363-55009057 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" "DNA-binding, Endonuclease, Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 52.7;Syncytiotrophoblasts: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048577 Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" Vesicles "HPA048577: AB_2680448" "unprognostic (2.90e-2)" "prognostic favorable (6.17e-4)" "unprognostic (4.32e-2)" "unprognostic (2.39e-1)" "unprognostic (1.62e-1)" "unprognostic (5.62e-2)" "prognostic unfavorable (6.13e-7)" "unprognostic (5.89e-2)" "unprognostic (4.87e-2)" "prognostic favorable (5.21e-4)" "unprognostic (7.46e-2)" "unprognostic (3.16e-1)" "unprognostic (6.86e-2)" "unprognostic (1.03e-2)" "unprognostic (3.17e-2)" "unprognostic (1.40e-1)" "prognostic favorable (6.63e-4)" 7.2 8.9 6.1 8.8 6.3 10.0 7.2 6.0 6.6 7.6 6.5 8.9 8.9 7.4 8.5 15.5 7.3 6.3 9.0 5.9 6.4 10.8 11.0 7.2 11.3 6.4 6.3 9.6 7.4 7.1 7.0 9.0 6.3 7.8 10.5 2.3 7.0 6.6 7.5 12.2 9.1 7.0 6.3 11.2 7.9 4.1 6.6 10.9 6.3 7.3 13.5 10.2 9.4 6.7 36.9 32.4 12.5 18.3 17.9 11.9 21.3 14.8 19.8 28.0 27.2 17.8 30.0 24.1 22.7 14.0 33.0 26.9 29.1 28.2 21.0 19.7 22.1 29.4 31.6 18.3 11.5 18.3 26.6 11.8 22.6 39.6 14.2 13.2 22.6 25.3 15.4 15.9 21.2 35.7 24.9 23.8 25.0 17.4 38.6 21.8 20.8 26.4 15.2 18.1 11.6 12.7 28.0 33.4 14.7 28.5 26.4 14.1 13.1 16.6 23.9 33.7 19.6 16.4 22.9 19.9 17.7 30.9 20.1 16.2 11.5 13.1 10.2 14.4 8.6 8.2 9.6 10.2 13.7 8.5 8.5 8.4 4.1 42.0 13.4 7.4 11.6 10.1 6.1 6.3 6.0 6.6 5.9 6.4 6.4 6.3 6.3 6.3 6.6 6.7 6.1 3.2 11.8 1.6 12.7 12.9 12.5 20.1 6.8 3.6 7.2 7.1 5.9 15.7 14.9 11.0 0.0 52.7 7.1 17.9 15.6 31.5 0.3 6.0 5.7 11.5 6.1 31.5 0.8 15.1 35.3 7.6 10.2 9.7 8.8 13.1 10.4 11.4 24.2 6.7 0.7 10.1 10.2 10.9 11.1 1.1 5.9 12.0 0.0 1.9 21.7 5.2 16.5 1.0 1.9 20.5 19.1 8.6 9.8 10.5 16.6 21.6 11.8 2.1 19.7 4.4 6.9 1.4 10.6 13.8 12.6 47.6 11.6 12.4 13.7 13.2 APLP2 "APPH, APPL2" ENSG00000084234 "Amyloid beta precursor like protein 2" Q06481 11 130068147-130144811 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "DNA-binding, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 249.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039319 Approved Approved Vesicles NA NA 1500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA039319: AB_10673141" "unprognostic (2.83e-2)" "unprognostic (1.29e-1)" "unprognostic (2.06e-1)" "unprognostic (3.18e-2)" "unprognostic (1.24e-2)" "unprognostic (1.10e-2)" "prognostic unfavorable (3.37e-4)" "unprognostic (3.86e-2)" "unprognostic (2.33e-1)" "unprognostic (2.70e-2)" "unprognostic (3.12e-3)" "unprognostic (7.44e-2)" "prognostic favorable (1.33e-9)" "unprognostic (3.20e-3)" "unprognostic (4.95e-2)" "prognostic favorable (2.90e-4)" "unprognostic (4.42e-2)" 217.2 130.2 125.6 144.0 126.0 196.5 192.3 164.7 157.9 170.4 252.6 209.9 272.4 176.6 138.6 134.2 167.6 201.8 271.6 131.0 153.2 359.9 334.8 391.4 77.5 130.9 137.5 180.8 136.0 291.5 87.1 324.8 133.1 287.7 176.7 540.8 135.3 291.0 65.9 113.3 226.6 211.5 135.4 95.7 149.7 54.9 157.9 81.5 607.8 85.2 56.8 199.1 129.6 152.8 216.7 170.3 307.1 281.2 1259.7 847.8 393.7 598.6 741.1 294.2 251.8 1300.5 1541.3 107.9 1515.3 1422.2 322.4 540.4 229.1 567.6 168.0 165.6 206.4 180.9 116.7 502.9 191.9 556.7 363.8 566.4 367.8 244.5 469.5 1520.2 912.7 34.1 180.7 228.9 495.2 205.7 26.9 245.3 182.8 256.8 301.1 70.0 69.8 105.5 758.9 589.6 109.9 239.0 706.9 368.0 92.0 535.8 582.2 489.5 1567.6 314.1 211.7 496.8 281.9 33.8 50.6 245.5 347.0 487.7 221.0 55.1 249.3 65.3 17.9 122.2 13.5 16.3 12.7 17.0 110.1 44.8 9.4 12.6 160.8 15.6 94.6 10.5 20.0 149.5 125.6 126.0 164.7 157.9 131.0 153.2 130.9 137.5 133.1 135.4 157.9 152.8 239.6 942.3 550.3 37.9 74.4 106.7 175.4 497.0 78.6 967.9 252.9 183.1 262.0 254.5 460.6 404.6 706.8 798.1 72.0 354.2 52.8 305.5 13.6 211.0 191.3 220.3 92.8 156.3 99.0 107.1 130.3 253.5 86.6 432.8 103.5 109.6 127.1 498.2 652.4 240.6 133.5 159.8 463.9 287.6 214.3 13.8 167.4 405.5 96.0 54.4 293.1 396.1 56.7 45.8 31.6 276.5 220.7 214.4 45.5 190.1 352.0 244.9 258.3 729.0 190.7 148.9 207.7 182.8 240.4 81.6 109.4 927.3 58.8 165.9 161.5 215.4 APOA1 ENSG00000118137 "Apolipoprotein A1" P02647 11 116835751-116837622 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Amyloidosis, Atherosclerosis, Cancer-related genes, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 19248.5" "Group enriched" "Detected in many" 21 "Hepatocytes: 27332.1;Proximal enterocytes: 18348.1" "Cancer enriched" "Detected in many" 48 "liver cancer: 4515.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in many" 17 "Hep G2: 3460.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB016778, HPA046715" Supported Approved Vesicles,Cytosol "Secreted to blood" NA NA 1450000000000 110000000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles Cytosol "CAB016778: , HPA046715: AB_2679768" "unprognostic (1.88e-3)" "unprognostic (4.53e-2)" "unprognostic (7.46e-2)" "unprognostic (4.00e-3)" "unprognostic (3.70e-2)" "unprognostic (1.41e-1)" "prognostic favorable (5.05e-4)" "unprognostic (5.40e-2)" "unprognostic (1.89e-1)" "unprognostic (9.60e-3)" "unprognostic (1.59e-3)" "unprognostic (7.02e-2)" "prognostic unfavorable (1.67e-8)" "unprognostic (3.46e-3)" "unprognostic (1.15e-1)" "unprognostic (6.24e-2)" "unprognostic (9.54e-2)" 3.2 1.4 1.2 3.6 1.2 0.0 2.1 1.1 1.4 0.8 0.8 7.4 1709.3 3.5 0.4 1.1 6.1 1.7 67.2 1.0 1.1 3.7 19248.5 2.7 3.2 1.1 1.1 23.1 2.5 0.0 4.2 1.6 1.1 1.1 0.2 0.1 0.7 1.0 0.8 1.0 4053.7 2.1 1.1 9.0 14.6 384.5 1.2 0.9 3.7 0.2 0.1 0.5 1.5 1.2 0.0 0.0 0.6 0.1 0.0 0.0 15.0 0.0 0.0 0.0 0.0 203.4 0.3 3.1 6.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.1 7.3 1.9 3460.4 0.0 16.6 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.3 0.0 0.2 0.3 15.0 1.2 1.2 0.1 0.5 15.0 20.3 0.0 2.6 5.7 20.7 8.9 0.0 0.0 3.9 0.0 0.1 2.6 0.0 0.4 2.1 0.1 1.2 0.2 4.9 0.0 5.5 0.2 0.0 0.0 0.0 0.8 0.2 0.0 0.0 0.0 0.5 0.2 0.1 0.2 0.5 0.0 0.2 0.0 1.2 0.6 0.1 1.2 1.2 1.1 1.4 1.0 1.1 1.1 1.1 1.1 1.1 1.2 1.2 2.0 3.2 3.3 0.3 49.7 0.1 0.5 0.2 0.6 0.5 0.9 0.9 37.0 479.0 1.3 0.0 0.0 0.6 5.1 0.4 0.0 0.1 36.9 15.2 4.3 50.3 1.8 541.9 0.5 1.1 4.2 5.8 17.9 1.7 2.5 419.2 458.7 27332.1 3.3 0.0 0.8 458.8 0.0 681.2 2.0 149.7 22.4 2.1 0.0 0.0 0.0 0.3 3.1 0.0 0.3 0.3 458.2 4.9 1.0 0.1 18348.1 9.0 0.4 0.6 6.6 1.6 13.0 39.8 11.2 0.0 0.6 4.2 35.7 1051.7 175.7 0.3 APOA4 ENSG00000110244 "Apolipoprotein A4" P06727 11 116820700-116823304 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "intestine: 3112.4" "Cell type enriched" "Detected in some" 44 "Proximal enterocytes: 10311.5" "Cancer enriched" "Detected in some" 29 "liver cancer: 291.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 7.7;CACO-2: 8.0;Hep G2: 7.7;NB-4: 7.3;RPMI-8226: 12.5;SH-SY5Y: 10.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001352, HPA002549, CAB068250, CAB068251, CAB068252" Enhanced Approved Vesicles "Secreted to blood" NA NA 61200000000 74000000000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB068250: AB_2665657, CAB068251: AB_2665659, CAB068252: AB_2665658, HPA001352: AB_1078179, HPA002549: AB_1078177" "unprognostic (8.81e-2)" "unprognostic (2.12e-2)" "unprognostic (1.75e-2)" "unprognostic (7.91e-2)" 0.3 0.0 0.0 2.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.9 2204.9 1.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 257.2 0.0 2.4 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 3112.4 3.0 0.0 0.1 4.6 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 3.1 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 77.5 0.0 0.0 0.0 234.3 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 221.5 0.0 0.0 0.0 10311.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 87.7 0.0 APOB ENSG00000084674 "Apolipoprotein B" P04114 2 21001429-21044073 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Atherosclerosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 143 "intestine: 304.3;liver: 1191.0" "Group enriched" "Detected in some" 8 "Hepatocytes: 2967.4;Proximal enterocytes: 1585.9" "Cancer enriched" "Detected in some" 99 "liver cancer: 295.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 30 "Hep G2: 1079.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016070, HPA049793" Supported Supported Vesicles,Cytosol "Secreted to blood" NA NA 1490000000000 100000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Vesicles, Cytosol" "CAB016070: AB_626690, HPA049793: AB_2680885" "unprognostic (1.63e-2)" "unprognostic (2.71e-2)" "unprognostic (1.75e-1)" "unprognostic (1.06e-1)" "unprognostic (1.04e-2)" "unprognostic (7.31e-2)" "unprognostic (1.46e-2)" "unprognostic (6.53e-3)" "unprognostic (4.43e-2)" "unprognostic (8.89e-3)" "unprognostic (3.01e-1)" "unprognostic (4.59e-3)" "unprognostic (3.60e-3)" "unprognostic (2.89e-2)" "unprognostic (2.38e-1)" "unprognostic (2.99e-1)" "unprognostic (6.23e-2)" 2.7 0.0 0.1 0.2 0.2 0.1 0.9 0.1 0.1 0.7 0.2 0.4 181.4 0.2 0.0 0.1 0.1 0.5 5.2 0.1 0.3 0.3 1191.0 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.3 0.2 0.1 0.0 0.0 0.1 0.1 0.5 304.3 0.2 0.2 0.5 0.3 0.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.0 35.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 1079.8 0.0 0.6 0.1 0.8 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.5 0.6 0.0 0.6 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.3 0.2 0.2 0.3 0.2 0.2 0.3 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 277.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 1.6 3.5 0.0 104.2 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.1 52.8 2967.4 0.1 0.0 0.2 30.8 0.0 69.4 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 32.5 1.5 0.0 0.0 1585.9 0.6 0.0 0.0 0.0 1.1 0.2 0.5 0.3 0.0 0.0 0.0 3.9 0.9 14.5 0.0 APOE AD2 ENSG00000130203 "Apolipoprotein E" P02649 19 44905791-44909393 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Hyperlipidemia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adrenal gland: 3453.9;liver: 6592.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 9363.4;Hofbauer cells: 6072.6;Muller glia cells: 9454.8;Peritubular cells: 4958.2;Proximal tubular cells: 8155.9;Theca cells: 7201.0" "Cancer enhanced" "Detected in all" "liver cancer: 3183.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1867.0;CACO-2: 466.1;Hep G2: 935.3;HSkMC: 1374.2;SK-MEL-30: 1956.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008363, HPA065539, HPA068768, CAB069921" Enhanced Approved Vesicles "Secreted to blood" NA NA 51800000000 29000000000 "Cluster 15: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB008363: AB_590560, CAB069921: AB_920623, HPA065539: AB_2685509, HPA068768: AB_2686029" "unprognostic (8.98e-2)" "unprognostic (2.32e-2)" "unprognostic (2.49e-2)" "unprognostic (5.28e-2)" "unprognostic (3.77e-2)" "unprognostic (7.25e-2)" "unprognostic (5.22e-3)" "unprognostic (6.13e-2)" "unprognostic (5.06e-2)" "unprognostic (4.13e-1)" "unprognostic (5.78e-2)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (7.76e-2)" "unprognostic (1.64e-1)" "unprognostic (1.12e-3)" "unprognostic (4.13e-2)" 522.1 3453.9 813.4 92.8 1164.2 66.5 325.1 775.0 943.2 271.2 329.2 130.9 40.3 81.5 20.0 37.2 72.2 100.2 176.3 606.1 841.6 1066.0 6592.5 258.8 352.2 1016.0 1037.0 508.2 41.9 34.5 110.9 102.2 1106.9 45.4 22.9 87.6 80.5 10.8 31.1 381.2 165.9 12.6 823.2 620.3 83.3 140.5 962.6 57.8 146.4 10.4 46.1 93.4 135.5 964.4 3.2 5.2 9.5 2.6 1867.0 76.3 69.4 1.5 4.3 8.4 1.4 466.1 2.8 2.0 9.9 0.3 9.1 6.4 12.6 2.1 0.7 1.7 4.0 3.3 1.7 935.3 192.4 6.8 2.3 1374.2 2.5 14.8 1.3 15.6 1.0 0.7 124.9 2.8 1.2 3.3 1.9 2.5 243.2 3.0 1.3 2.6 8.0 1.8 2.8 0.9 5.6 2.4 4.5 1.4 1956.0 131.6 165.3 52.8 3.3 13.2 3.1 1.4 1.6 5.9 8.6 3.8 5.9 4.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 813.4 1164.2 775.0 943.2 606.1 841.6 1016.0 1037.0 1106.9 823.2 962.6 964.4 136.7 0.0 8.2 444.0 66.1 935.2 12.3 18.3 67.7 81.7 86.7 565.8 2.2 450.4 5.2 228.1 41.7 46.3 6.0 2.2 682.9 1.8 73.6 33.8 936.6 140.2 0.0 331.6 1.1 0.7 43.8 860.7 3.6 22.9 174.4 103.6 208.9 9363.4 6072.6 38.7 2.1 0.6 4.1 718.0 292.6 355.3 2629.4 940.6 2481.3 60.9 70.3 9454.8 0.0 12.1 2.2 0.6 0.3 4958.2 7.2 15.0 0.2 8155.9 1.0 311.4 223.5 2958.4 345.5 14.8 12.8 15.1 1684.9 74.3 60.6 7201.0 1.7 4.7 APOL4 APOLIV ENSG00000100336 "Apolipoprotein L4" Q9BPW4 22 36189124-36204840 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 32.7;Enteroendocrine cells: 14.9;Glandular and luminal cells: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.6;myeloid DC: 1.5" "Group enriched" "Detected in many" 4 "dendritic cells: 1.5;monocytes: 1.6" "Cell line enhanced" "Detected in some" "BEWO: 18.7;HDLM-2: 109.9;HSkMC: 16.1;K-562: 23.7;SCLC-21H: 47.9" "HPA049797, HPA055435" Uncertain Supported Vesicles "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" Vesicles "HPA049797: AB_2680887, HPA055435: AB_2682816" "unprognostic (2.73e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" "unprognostic (1.51e-1)" "unprognostic (5.31e-1)" "unprognostic (3.39e-2)" "unprognostic (2.44e-2)" "unprognostic (1.55e-1)" "unprognostic (1.91e-1)" "prognostic favorable (3.45e-4)" "unprognostic (1.33e-2)" "unprognostic (2.24e-1)" "prognostic unfavorable (2.00e-5)" "unprognostic (4.26e-2)" "unprognostic (3.69e-1)" "unprognostic (4.18e-2)" "prognostic favorable (2.40e-6)" 13.5 1.0 0.8 6.0 0.8 1.5 14.7 0.9 2.2 4.6 0.5 3.3 4.8 3.9 1.6 4.3 5.9 6.3 5.3 0.9 1.6 8.1 2.0 12.8 4.7 2.5 1.3 3.9 1.0 0.3 9.4 3.3 1.9 14.7 3.4 0.1 5.8 3.4 1.1 4.1 3.8 2.4 1.0 3.2 4.9 0.7 1.1 2.9 3.2 1.3 1.8 12.1 3.6 0.8 0.0 0.0 0.0 0.0 0.2 2.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 109.9 0.0 5.7 0.0 0.0 0.1 0.0 0.2 16.1 0.0 0.0 0.0 0.0 0.8 0.0 23.7 0.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.0 1.0 47.9 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.3 0.1 0.2 1.6 0.0 0.0 0.9 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.8 0.8 0.9 2.2 0.9 1.6 2.5 1.3 1.9 1.0 1.1 0.8 7.0 0.0 6.7 0.3 0.2 1.3 0.7 1.5 0.0 0.3 4.6 2.2 1.1 1.5 3.4 0.0 0.0 0.5 0.1 0.0 3.9 0.2 0.0 32.7 12.4 6.6 14.9 4.2 0.0 0.7 1.0 10.4 0.0 52.6 2.5 0.0 2.5 0.4 2.3 1.7 0.1 0.8 0.0 6.2 6.5 0.0 2.8 8.8 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 1.2 0.2 0.3 4.2 0.0 0.0 9.0 1.9 0.0 0.0 0.0 1.1 6.2 1.3 0.5 0.4 1.9 APP AD1 ENSG00000142192 "Amyloid beta precursor protein" P05067 21 25880550-26171128 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Apoptosis, Cell adhesion, Endocytosis, Notch signaling pathway" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Alzheimer disease, Amyloidosis, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 870.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 38.1" "Lineage enriched" "Detected in many" 5 "dendritic cells: 38.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000157, HPA001462" Enhanced Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 26000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" Vesicles "CAB000157: AB_323833, HPA001462: AB_1078185" "unprognostic (3.30e-1)" "unprognostic (1.02e-2)" "unprognostic (1.90e-1)" "unprognostic (1.24e-1)" "unprognostic (1.92e-1)" "unprognostic (3.69e-3)" "unprognostic (2.54e-1)" "unprognostic (8.22e-2)" "unprognostic (1.28e-1)" "unprognostic (9.45e-2)" "unprognostic (4.28e-2)" "unprognostic (5.35e-2)" "prognostic favorable (2.79e-6)" "unprognostic (3.77e-2)" "unprognostic (2.46e-1)" "unprognostic (5.23e-2)" "unprognostic (2.08e-3)" 249.9 498.0 413.0 157.4 457.6 134.4 447.5 413.1 572.4 264.2 396.8 357.2 226.4 281.1 293.3 178.6 308.1 350.8 389.0 456.2 405.3 532.5 298.2 279.4 78.9 425.0 481.9 306.2 323.5 278.6 155.4 451.9 448.7 260.6 328.5 209.3 270.7 343.6 107.5 218.6 200.3 379.9 419.7 154.4 213.5 165.6 426.4 159.2 469.9 176.0 78.2 304.9 151.7 523.5 388.7 489.9 538.4 448.5 707.7 869.8 559.8 757.1 1029.2 386.6 449.3 286.4 941.0 0.9 848.3 614.8 505.1 255.6 326.4 921.6 324.4 14.7 253.1 0.8 275.6 204.1 688.0 372.0 19.6 790.4 990.7 456.8 823.0 1584.3 1750.7 158.6 0.8 39.0 614.5 433.1 6.5 4.0 416.2 644.9 418.6 241.2 505.2 325.3 1283.3 270.1 267.3 385.6 824.0 549.0 393.4 720.0 482.4 400.1 1837.1 850.8 350.2 310.4 371.6 232.3 3.1 4.8 690.4 1.6 836.3 1.1 7.5 0.0 0.2 2.2 0.3 0.8 2.2 0.7 5.6 2.2 2.3 0.6 1.5 0.5 1.6 38.1 0.6 3.3 413.0 457.6 413.1 572.4 456.2 405.3 425.0 481.9 448.7 419.7 426.4 523.5 330.2 109.0 39.6 70.5 47.6 181.6 215.6 449.0 306.7 45.2 280.3 199.6 143.2 296.0 214.0 502.1 29.2 472.6 180.7 395.2 56.7 398.7 46.1 78.8 162.2 416.0 162.6 29.2 481.6 180.4 141.2 309.5 164.7 110.7 8.2 100.3 539.7 125.7 76.3 84.1 525.5 303.1 256.3 61.6 79.9 61.8 242.6 69.9 161.9 189.3 89.9 329.9 4.1 423.2 870.8 205.4 223.1 296.8 24.0 187.5 95.2 165.8 164.7 24.5 118.3 336.5 198.5 38.3 86.9 85.9 106.1 552.1 27.0 111.4 283.5 133.6 APPL1 APPL ENSG00000157500 "Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1" Q9UKG1 3 57227726-57278105 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 28.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011138 Approved Approved "Vesicles,Plasma membrane,Actin filaments,Cytosol" NA No 10000 "Cluster 37: B-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" "Vesicles, Plasma membrane" "Actin filaments, Cytosol" "HPA011138: AB_1844959" "unprognostic (1.39e-1)" "unprognostic (3.45e-2)" "unprognostic (1.06e-2)" "unprognostic (2.01e-1)" "unprognostic (3.68e-2)" "unprognostic (2.31e-3)" "unprognostic (1.30e-3)" "unprognostic (1.81e-2)" "unprognostic (1.05e-1)" "unprognostic (8.36e-2)" "unprognostic (9.05e-3)" "unprognostic (5.55e-2)" "prognostic favorable (7.26e-5)" "unprognostic (3.99e-2)" "unprognostic (8.76e-2)" "unprognostic (1.12e-2)" "unprognostic (1.55e-1)" 15.6 11.6 9.5 14.8 9.7 15.1 18.9 12.9 11.3 17.1 6.8 14.2 12.6 17.1 10.6 16.9 11.7 13.0 24.7 9.7 11.3 16.5 12.9 13.6 16.7 9.8 10.1 22.7 29.6 25.1 7.8 14.3 10.1 15.0 14.0 13.5 15.2 14.4 44.2 20.1 14.6 15.3 10.4 15.8 15.2 8.0 10.2 18.9 19.8 26.6 19.6 13.4 11.9 10.7 30.2 12.9 12.2 45.4 21.2 29.7 26.2 15.5 9.5 15.4 17.8 14.9 17.5 47.3 6.2 24.6 24.7 5.9 33.7 27.3 26.6 36.1 15.0 27.6 19.5 16.1 22.7 59.6 19.1 21.8 24.3 19.3 21.3 31.3 25.3 30.2 9.0 30.0 17.8 10.4 48.7 15.4 19.5 21.6 21.7 1.7 49.1 26.1 27.7 16.7 12.5 26.5 21.1 32.3 21.0 16.7 15.7 39.6 23.4 25.1 17.5 37.4 29.9 27.0 41.8 33.2 27.4 29.1 17.1 2.0 5.3 3.8 3.7 4.5 4.9 17.9 3.8 3.3 10.9 28.3 3.3 2.5 1.4 7.4 3.6 18.0 1.9 2.7 9.5 9.7 12.9 11.3 9.7 11.3 9.8 10.1 10.1 10.4 10.2 10.7 82.9 51.3 45.5 19.6 106.6 52.9 47.3 46.9 83.6 40.5 67.2 92.8 100.1 47.1 47.4 42.3 31.3 46.9 70.9 29.0 58.7 58.6 42.5 35.4 92.8 66.2 45.6 20.0 49.7 60.3 44.7 68.6 40.2 59.4 23.4 60.8 40.0 44.1 52.2 52.2 50.4 36.2 42.7 68.6 50.6 22.1 73.0 71.0 19.6 33.7 87.8 56.6 56.7 43.2 62.2 51.7 25.5 76.0 62.8 38.7 41.0 58.8 18.1 55.4 52.6 94.3 61.2 64.9 44.2 105.7 69.6 28.0 45.4 73.7 49.1 25.8 AQP10 ENSG00000143595 "Aquaporin 10" Q96PS8 1 154321090-154325325 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "intestine: 68.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.5;Erythroid cells: 1.3;granulocytes: 5.7;Hepatic stellate cells: 1.4;Macrophages: 4.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 18.0;HMC-1: 7.1;K-562: 21.0;SH-SY5Y: 4.8" "Not detected" "Not detected" "HPA062621, HPA065947" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" Vesicles "HPA062621: , HPA065947: AB_2685584" "unprognostic (6.84e-2)" "unprognostic (4.97e-2)" "unprognostic (4.19e-2)" "unprognostic (1.87e-1)" "unprognostic (1.09e-1)" "unprognostic (8.45e-4)" "unprognostic (1.63e-1)" "unprognostic (3.07e-1)" "unprognostic (4.08e-2)" "unprognostic (3.99e-1)" "unprognostic (1.22e-1)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (1.68e-1)" "unprognostic (7.64e-3)" 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 68.5 0.0 0.1 0.1 4.6 0.1 0.4 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 49.7 0.0 0.0 0.7 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 21.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.1 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.4 1.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.3 0.5 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.1 5.7 0.2 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.2 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.1 0.4 0.4 0.0 0.1 0.0 0.4 0.1 0.0 0.1 AQP11 ENSG00000178301 "Aquaporin 11" Q8NBQ7 11 77589391-77610356 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 28.6;liver: 16.1" "Cell type enhanced" "Detected in many" "Early spermatids: 42.0;Hepatocytes: 35.9;Late spermatids: 65.0;Muller glia cells: 30.7;Proximal enterocytes: 33.2;Spermatocytes: 56.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 8.2;GAMG: 12.3;Hep G2: 13.6;OE19: 7.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042879 Approved Nucleoplasm,Vesicles NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Vesicles "HPA042879: AB_10794919" "unprognostic (4.95e-2)" "unprognostic (7.61e-2)" "unprognostic (2.15e-2)" "unprognostic (9.62e-5)" "unprognostic (2.42e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-1)" "unprognostic (3.48e-2)" "unprognostic (2.65e-1)" "prognostic favorable (9.89e-4)" "unprognostic (1.16e-1)" "unprognostic (1.00e-1)" "unprognostic (1.73e-1)" "unprognostic (1.73e-2)" "unprognostic (2.44e-1)" "unprognostic (6.46e-2)" "unprognostic (1.66e-3)" 1.0 13.2 3.4 0.7 3.0 0.6 1.2 4.6 3.3 0.8 1.0 2.3 28.6 0.8 1.0 0.4 0.8 1.2 0.8 2.6 3.4 6.0 16.1 0.5 0.8 3.3 3.1 6.0 4.0 0.5 1.5 0.8 3.5 4.0 2.1 5.6 0.7 0.4 0.9 0.9 25.3 0.4 2.7 0.9 2.4 8.1 3.0 0.1 1.5 0.2 0.1 0.8 0.6 3.0 1.0 3.4 1.4 2.2 3.1 0.8 1.3 1.6 0.8 1.6 0.7 8.2 1.6 1.6 0.7 0.8 12.3 0.9 0.6 0.1 0.8 4.7 1.2 1.3 1.3 13.6 1.0 2.8 1.4 0.8 0.3 0.9 0.2 1.9 0.3 0.4 0.9 1.0 1.9 1.7 0.9 2.0 1.4 7.8 3.1 1.3 3.3 0.6 0.9 1.2 1.3 0.9 2.1 0.5 0.8 1.1 1.5 0.3 0.9 1.2 3.7 2.4 1.0 1.0 0.8 1.3 0.4 0.2 1.8 0.0 0.0 0.1 0.5 0.0 0.3 0.0 0.2 0.4 0.0 0.5 0.6 0.2 0.0 0.7 0.0 0.0 0.0 0.2 3.4 3.0 4.6 3.3 2.6 3.4 3.3 3.1 3.5 2.7 3.0 3.0 0.6 0.0 0.0 3.9 0.8 0.1 0.9 0.4 1.8 7.5 2.1 1.3 0.7 7.2 0.2 1.8 0.0 7.5 0.6 10.8 0.0 1.1 42.0 1.2 0.8 0.5 4.2 0.0 13.5 4.0 11.4 1.5 3.6 0.8 4.5 17.1 0.4 35.9 1.2 0.0 14.6 2.9 0.0 0.6 0.4 65.0 15.5 0.5 1.8 1.0 0.0 30.7 0.0 9.0 9.9 2.5 5.5 11.3 0.3 1.4 33.2 19.9 0.2 5.0 0.0 0.5 1.2 56.0 6.4 0.4 0.1 15.9 0.7 21.4 6.4 0.4 ARAP1 CENTD2 ENSG00000186635 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1" Q96P48 11 72685069-72793599 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020703, HPA070383" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 36000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "CAB020703: , HPA070383: AB_2686262" "unprognostic (3.60e-2)" "unprognostic (7.68e-2)" "unprognostic (6.19e-2)" "unprognostic (5.98e-2)" "unprognostic (5.76e-2)" "unprognostic (1.64e-2)" "prognostic unfavorable (6.45e-4)" "unprognostic (4.01e-2)" "unprognostic (4.07e-1)" "unprognostic (5.95e-2)" "prognostic favorable (2.04e-5)" "unprognostic (1.84e-1)" "unprognostic (1.05e-3)" "unprognostic (6.93e-2)" "unprognostic (2.57e-2)" "prognostic favorable (6.41e-4)" "unprognostic (7.56e-3)" 41.5 63.5 40.0 58.6 48.6 97.5 33.4 37.9 50.4 44.1 62.9 35.5 29.6 38.9 14.0 37.7 48.3 44.2 42.9 42.2 38.5 47.8 40.2 71.8 53.4 50.6 42.3 49.4 37.1 20.4 48.9 35.5 45.9 44.9 18.2 8.6 33.3 25.7 20.1 47.1 43.3 28.7 40.1 117.5 31.3 16.4 50.8 32.2 46.6 20.1 25.2 39.7 37.5 56.8 19.7 41.9 15.2 18.5 63.4 42.9 23.1 26.2 46.5 29.8 29.3 56.0 50.8 42.9 51.3 44.4 40.7 64.5 23.2 64.4 12.5 50.9 28.4 36.6 40.3 81.9 43.7 25.1 98.7 47.5 65.4 48.7 23.4 36.2 33.2 31.3 31.5 17.4 13.9 40.3 38.9 89.3 9.5 35.1 25.9 36.8 23.2 21.3 27.5 61.1 15.7 32.0 19.1 27.9 84.8 19.5 25.1 56.8 37.5 41.0 28.5 42.8 16.4 27.4 14.3 23.0 21.8 37.4 22.3 19.3 24.8 30.7 8.9 39.4 5.2 6.6 5.9 6.8 15.9 4.7 4.5 5.4 50.8 13.4 51.3 5.3 6.7 17.6 40.0 48.6 37.9 50.4 42.2 38.5 50.6 42.3 45.9 40.1 50.8 56.8 8.9 28.9 32.3 33.6 16.1 7.4 7.5 14.3 15.4 4.3 8.7 7.9 2.6 7.2 9.0 16.5 33.3 9.2 18.3 16.5 9.8 13.5 50.1 14.1 11.7 7.8 23.3 9.9 7.7 7.5 8.9 22.4 16.3 9.1 10.8 36.9 9.7 10.8 43.0 0.0 7.0 12.8 12.2 45.6 25.1 6.4 20.8 57.3 8.8 30.0 29.0 7.4 21.6 17.6 31.5 12.1 10.9 15.1 12.3 4.8 20.9 5.3 20.2 2.8 0.0 8.6 8.8 0.4 2.8 10.8 5.4 4.9 12.4 10.5 15.1 7.4 ARC "Arg3.1, KIAA0278" ENSG00000198576 "Activity regulated cytoskeleton associated protein" Q7LC44 8 142611049-142614479 "Predicted intracellular proteins" "Endocytosis, Transport" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 122.9;pituitary gland: 67.6" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 57.0;Endometrial stromal cells: 47.8;Enteroendocrine cells: 164.2;Skeletal myocytes: 57.7" "Cancer enriched" "Detected in many" 12 "glioma: 36.1" "Group enriched" "Detected in all" 6 "cerebral cortex: 122.9;hippocampal formation: 34.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 8.1;HEK 293: 10.0;SCLC-21H: 23.6;U-2 OS: 11.5;U-87 MG: 12.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basal ganglia: 20.7;cerebral cortex: 75.1;hippocampal formation: 42.4;olfactory bulb: 22.9" "HPA056430, CAB079013" Supported Approved Vesicles,Microtubules NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 36: Stromal cells - Cell proliferation" "Vesicles, Microtubules" "CAB079013: , HPA056430: AB_2683130" "unprognostic (1.40e-3)" "unprognostic (2.95e-2)" "unprognostic (4.35e-3)" "unprognostic (4.87e-4)" "unprognostic (6.83e-2)" "unprognostic (8.12e-2)" "unprognostic (5.13e-2)" "unprognostic (1.77e-1)" "unprognostic (5.07e-2)" "unprognostic (9.43e-2)" "unprognostic (4.15e-3)" "unprognostic (1.40e-1)" "unprognostic (2.14e-2)" "unprognostic (1.01e-2)" "unprognostic (7.42e-2)" "unprognostic (1.54e-1)" "unprognostic (3.35e-2)" 14.2 10.2 6.6 0.4 8.2 0.2 1.2 4.5 122.9 3.3 2.7 1.6 0.2 0.9 0.9 1.6 1.9 2.0 2.1 34.2 14.1 4.0 0.3 8.1 0.0 6.4 4.0 0.6 4.0 0.0 67.6 0.9 4.8 0.8 0.1 0.8 0.8 3.8 0.4 10.9 1.1 0.3 3.6 0.7 8.7 0.6 8.9 0.1 1.0 0.4 0.1 0.7 4.5 13.4 0.0 0.1 0.4 8.1 0.1 0.8 0.0 1.7 0.0 0.4 0.2 0.2 0.0 0.0 1.1 0.3 0.3 0.1 0.5 0.0 0.0 0.0 10.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.4 0.1 0.0 0.0 0.1 3.5 0.0 0.0 3.7 1.4 1.8 0.0 0.8 0.0 0.0 0.0 23.6 5.5 0.6 0.0 0.3 0.0 0.1 0.1 0.0 1.3 11.5 0.9 0.2 2.2 0.1 0.0 12.8 0.0 3.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 8.2 4.5 122.9 34.2 14.1 6.4 4.0 4.8 3.6 8.9 13.4 19.7 0.0 3.0 1.6 1.9 5.1 16.6 2.6 1.2 8.4 33.2 57.0 4.5 4.3 0.8 0.0 0.0 0.1 5.8 6.0 0.0 1.6 0.1 9.2 47.8 9.8 164.2 0.0 17.0 0.0 0.4 24.1 21.9 10.3 0.0 0.5 7.5 0.0 1.6 3.3 0.8 6.2 4.1 0.8 7.0 0.0 0.3 8.2 7.2 1.0 0.1 15.2 0.0 3.5 0.8 0.1 0.0 1.9 1.1 10.3 0.3 0.0 0.3 2.8 0.0 57.7 27.0 0.2 0.6 4.7 6.5 0.1 4.2 0.5 4.1 2.7 ARCN1 COPD ENSG00000095139 "Archain 1" P48444 11 118572390-118603033 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037573, HPA044874" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA 140000 "Cluster 18: Basophils - Vesicular transport" "Cluster 29: Non-specific - Vesicular transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "Golgi apparatus, Cytosol" "HPA037573: AB_10696938, HPA044874: AB_2679126" "unprognostic (1.46e-2)" "unprognostic (4.97e-2)" "unprognostic (1.66e-1)" "unprognostic (3.20e-1)" "unprognostic (9.99e-2)" "unprognostic (2.30e-2)" "prognostic unfavorable (2.97e-5)" "unprognostic (3.10e-2)" "unprognostic (1.17e-1)" "unprognostic (1.31e-1)" "unprognostic (1.67e-3)" "unprognostic (9.39e-2)" "unprognostic (3.56e-2)" "unprognostic (7.99e-2)" "unprognostic (9.20e-2)" "unprognostic (4.14e-3)" "unprognostic (5.56e-3)" 75.4 67.7 47.5 53.8 51.0 30.4 67.5 52.0 60.5 78.0 61.2 65.0 59.2 69.2 111.1 72.5 60.5 51.6 75.6 46.8 50.9 58.3 91.6 62.6 53.2 51.2 51.3 65.5 119.7 61.9 88.7 54.7 51.1 68.8 67.1 39.2 79.6 64.5 51.1 60.9 64.9 71.0 50.0 57.9 71.8 46.2 50.5 58.8 65.2 55.0 62.2 66.4 60.9 57.2 90.9 72.6 135.3 98.9 174.0 172.7 66.6 244.8 208.5 102.4 120.7 239.4 116.6 96.4 199.7 275.7 148.0 123.7 160.5 139.5 151.5 128.0 66.3 211.6 56.7 151.4 197.1 140.4 121.8 157.8 117.6 175.0 168.7 149.3 162.2 95.0 106.8 139.2 201.3 157.0 123.2 130.8 85.3 207.7 92.4 107.9 134.2 147.4 137.3 107.0 88.3 86.6 130.2 129.0 70.1 132.5 155.9 111.4 144.0 129.4 65.1 118.4 109.5 79.9 78.5 147.6 74.3 122.6 161.4 118.1 49.8 50.7 52.7 59.8 69.0 39.5 51.7 51.3 54.0 35.4 48.0 44.7 41.5 64.5 64.5 44.9 53.9 55.8 47.5 51.0 52.0 60.5 46.8 50.9 51.2 51.3 51.1 50.0 50.5 57.2 43.6 35.3 47.9 12.4 32.2 31.6 38.5 31.5 23.9 22.4 39.4 27.9 46.5 24.3 41.9 31.3 4.2 17.2 45.6 68.4 9.8 34.3 11.1 38.4 72.2 43.1 40.2 14.9 15.4 37.8 36.1 44.9 39.3 50.4 39.3 31.9 31.4 55.7 30.3 18.5 17.7 80.2 22.4 36.0 37.6 8.5 48.1 35.3 23.2 11.2 49.0 17.3 26.8 17.1 20.2 46.9 35.8 41.3 68.3 51.5 56.2 30.5 46.2 13.6 19.7 52.7 45.7 44.8 47.6 30.4 34.7 30.2 38.4 43.9 42.6 51.6 ARFGAP1 "ARF1GAP, bA261N11.3, FLJ10767" ENSG00000101199 "ADP ribosylation factor GTPase activating protein 1" Q8N6T3 20 63272785-63289790 "Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051019, HPA056273" Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 71: Testis - DNA repair" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus, Vesicles" Cytosol "HPA051019: AB_2681313, HPA056273: AB_2683084" "unprognostic (1.81e-1)" "unprognostic (4.64e-2)" "unprognostic (1.27e-1)" "unprognostic (3.93e-1)" "unprognostic (1.38e-1)" "unprognostic (1.24e-1)" "unprognostic (1.57e-3)" "unprognostic (7.76e-2)" "unprognostic (8.86e-3)" "unprognostic (8.62e-2)" "prognostic favorable (4.57e-4)" "unprognostic (3.23e-2)" "prognostic unfavorable (3.48e-7)" "unprognostic (1.16e-1)" "unprognostic (7.59e-2)" "unprognostic (4.34e-2)" "unprognostic (2.86e-1)" 12.9 16.7 13.1 15.5 14.3 12.1 13.0 13.1 20.6 19.1 8.4 19.1 13.1 20.8 8.6 15.8 16.1 16.8 14.1 14.4 11.0 15.9 17.8 16.1 16.1 14.1 12.0 17.7 28.3 11.8 63.9 15.4 14.2 20.1 9.5 11.7 18.4 13.4 14.1 19.1 18.1 12.5 9.1 20.5 18.5 24.2 12.5 14.2 17.9 7.5 11.3 16.5 14.9 15.9 32.6 60.2 25.6 30.6 30.3 32.5 51.2 46.4 36.5 90.7 45.5 145.2 35.2 24.5 41.7 55.4 41.5 43.2 23.5 73.8 28.5 15.8 26.7 19.4 64.7 128.4 46.2 28.8 38.4 28.5 46.9 44.0 24.9 30.5 32.9 25.5 34.9 27.8 25.1 53.2 52.9 28.0 34.5 34.3 51.9 29.7 36.8 23.6 22.3 38.8 27.3 29.9 55.1 58.7 59.2 20.7 42.8 36.4 42.8 56.0 77.3 35.0 37.6 28.4 20.2 26.5 56.9 20.0 35.3 4.8 5.7 6.4 5.6 7.1 6.4 3.0 3.1 5.3 5.7 4.2 3.0 3.0 2.4 4.7 9.5 4.2 4.1 6.0 13.1 14.3 13.1 20.6 14.4 11.0 14.1 12.0 14.2 9.1 12.5 15.9 12.6 22.4 30.7 34.9 11.2 10.1 6.0 8.6 4.0 26.6 17.6 14.4 12.4 11.5 14.4 12.9 33.3 12.5 15.4 37.6 9.8 12.2 15.9 11.0 17.1 14.2 24.5 9.5 14.5 15.4 24.9 16.3 50.4 14.9 15.9 30.6 13.6 23.3 14.9 21.9 14.9 40.4 2.0 14.4 11.5 23.3 12.5 13.5 12.4 5.6 12.3 11.8 15.5 18.6 24.8 28.2 18.3 9.8 17.8 11.6 17.4 11.5 18.8 20.1 6.6 11.1 14.9 21.3 7.4 6.7 8.5 15.2 10.3 16.8 24.0 9.2 ARFGEF2 BIG2 ENSG00000124198 "ADP ribosylation factor guanine nucleotide exchange factor 2" Q9Y6D5 20 48921711-49036693 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 81.5" "Cell type enhanced" "Detected in all" "Excitatory neurons: 102.6;Inhibitory neurons: 96.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026078, CAB026382" Supported Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "Vesicles, Cytosol" "CAB026382: , HPA026078: AB_1844983" "unprognostic (1.50e-2)" "unprognostic (9.56e-3)" "unprognostic (4.14e-2)" "unprognostic (4.94e-3)" "unprognostic (5.30e-2)" "unprognostic (6.94e-2)" "unprognostic (1.57e-2)" "unprognostic (2.99e-1)" "unprognostic (8.47e-2)" "unprognostic (1.34e-1)" "unprognostic (1.12e-2)" "unprognostic (1.11e-1)" "prognostic favorable (6.15e-7)" "unprognostic (1.68e-1)" "unprognostic (1.56e-1)" "unprognostic (2.85e-1)" "unprognostic (3.90e-2)" 9.1 20.2 2.8 8.7 4.1 10.4 15.8 1.9 5.8 11.5 7.9 14.2 13.7 9.0 5.9 11.0 7.5 8.5 13.4 4.5 3.9 15.3 12.4 7.8 9.8 2.6 3.2 7.7 19.2 81.5 8.7 9.2 3.5 10.6 15.7 6.8 11.0 9.7 11.8 11.1 10.9 9.5 1.9 10.4 16.2 13.6 3.5 11.3 23.8 18.2 14.2 11.1 8.2 5.0 18.3 16.5 8.9 5.1 18.0 14.8 21.8 15.5 19.5 36.6 19.0 37.1 19.8 25.5 22.1 19.7 33.8 21.0 18.6 23.6 33.8 9.0 7.6 17.5 17.9 25.4 19.7 22.6 19.7 15.0 21.6 23.9 27.6 12.7 28.4 11.7 15.0 22.3 20.8 6.3 13.0 6.8 8.3 20.5 17.4 14.0 25.5 30.3 13.6 23.4 7.1 9.0 42.6 66.0 23.4 10.3 26.6 18.6 34.5 35.6 16.5 18.2 13.1 35.9 35.0 18.7 23.4 10.7 11.6 1.1 0.6 0.2 0.5 0.4 0.6 0.5 0.5 0.4 0.7 0.9 0.8 0.7 0.3 0.3 0.3 0.9 0.1 0.3 2.8 4.1 1.9 5.8 4.5 3.9 2.6 3.2 3.5 1.9 3.5 5.0 16.6 19.2 26.0 37.2 21.2 11.3 12.2 11.0 11.4 15.3 27.7 14.7 40.7 17.2 20.0 11.0 14.6 10.5 14.7 30.4 1.9 10.9 16.6 19.5 17.1 19.5 12.5 14.3 102.6 13.3 10.0 12.6 16.3 24.7 15.2 11.0 20.7 27.8 10.8 11.8 96.7 23.3 8.2 15.7 13.9 24.6 10.2 17.8 10.6 60.9 15.6 5.4 10.3 43.2 57.0 15.5 21.6 11.3 29.0 24.1 18.6 11.5 17.2 16.1 6.6 14.2 12.5 32.6 20.4 17.5 15.5 30.0 13.2 16.6 21.0 21.2 ARFIP1 HSU52521 ENSG00000164144 "ADP ribosylation factor interacting protein 1" P53367 4 152779937-152918463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005080, HPA037375, HPA063759" Enhanced Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Vesicles" Nucleoplasm "CAB005080: AB_2058797, HPA037375: AB_2675440, HPA063759: AB_2685114" "unprognostic (1.06e-1)" "unprognostic (1.19e-1)" "prognostic favorable (5.75e-5)" "unprognostic (1.49e-3)" "unprognostic (4.32e-1)" "unprognostic (1.24e-1)" "unprognostic (3.54e-2)" "unprognostic (5.34e-1)" "unprognostic (1.03e-2)" "unprognostic (3.56e-1)" "unprognostic (3.60e-2)" "unprognostic (1.82e-2)" "prognostic favorable (2.83e-10)" "unprognostic (1.83e-1)" "unprognostic (1.32e-1)" "unprognostic (7.02e-2)" "unprognostic (4.22e-3)" 16.8 14.8 7.9 15.8 8.7 3.7 23.4 9.9 10.8 22.5 9.9 28.1 23.2 21.7 20.5 20.9 18.5 19.9 10.2 7.3 9.3 19.8 15.4 16.8 15.1 9.3 8.0 17.6 10.5 22.4 10.5 18.0 9.5 21.1 27.8 20.2 13.7 17.2 6.6 17.3 21.3 19.8 9.4 18.3 22.7 12.1 8.3 12.0 20.1 10.4 14.8 23.5 15.2 11.4 25.8 18.4 25.1 25.7 37.2 37.9 30.6 29.5 40.5 28.7 26.9 21.3 51.3 20.6 9.9 40.5 22.7 18.1 26.3 29.1 35.3 16.9 16.2 20.0 18.0 20.5 26.1 38.2 41.7 26.6 30.9 24.8 23.8 30.7 26.4 11.8 23.5 43.3 39.8 28.6 22.7 19.8 21.8 29.9 18.5 12.6 14.7 19.2 50.7 32.1 32.8 26.0 22.1 40.7 30.2 23.5 37.7 19.6 17.3 27.8 20.1 26.8 21.4 48.2 42.8 28.1 35.3 38.2 40.0 31.5 27.3 42.2 14.5 31.1 14.6 19.0 11.2 12.2 24.8 17.7 8.7 11.8 81.6 29.1 30.7 3.1 18.5 18.7 7.9 8.7 9.9 10.8 7.3 9.3 9.3 8.0 9.5 9.4 8.3 11.4 28.5 6.4 31.8 40.5 20.3 29.6 18.4 30.7 34.1 17.2 26.2 19.7 10.2 20.0 29.1 38.6 0.0 28.6 15.6 40.9 27.4 27.4 46.3 42.2 33.0 23.8 38.9 12.0 44.5 18.3 27.0 28.8 40.2 50.7 22.8 14.2 17.2 19.8 22.1 18.5 42.8 39.1 34.6 23.8 18.0 21.6 22.4 24.5 21.4 89.9 19.5 35.9 23.7 76.4 75.6 24.4 28.2 21.8 11.8 23.6 23.8 34.2 31.9 24.2 32.9 20.6 27.8 31.7 29.5 31.9 34.0 43.9 17.7 89.2 31.7 30.3 ARHGAP1 "CDC42GAP, p50rhoGAP, RhoGAP" ENSG00000175220 "Rho GTPase activating protein 1" Q07960 11 46677080-46700619 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 92.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004689, HPA008285" Approved Approved Approved Vesicles NA NA 11000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA004689: AB_1078194, HPA008285: AB_1078195" "unprognostic (1.06e-1)" "unprognostic (2.73e-1)" "unprognostic (2.05e-3)" "unprognostic (5.19e-2)" "unprognostic (2.48e-2)" "unprognostic (9.07e-2)" "prognostic unfavorable (2.14e-4)" "unprognostic (1.34e-3)" "unprognostic (1.24e-1)" "unprognostic (7.96e-2)" "unprognostic (1.35e-2)" "unprognostic (4.94e-1)" "unprognostic (4.79e-2)" "unprognostic (4.13e-2)" "unprognostic (3.49e-2)" "unprognostic (2.55e-1)" "unprognostic (9.24e-2)" 84.5 49.2 40.9 38.0 48.3 33.4 61.8 33.4 46.1 71.3 31.2 62.8 25.7 93.7 21.5 75.0 68.4 50.7 112.3 39.1 41.0 41.5 46.2 38.4 30.7 45.7 43.2 46.4 36.5 24.7 36.8 39.0 39.0 64.9 32.6 9.6 46.1 62.6 30.0 65.3 46.7 80.6 38.0 58.4 49.0 15.8 49.8 23.2 44.6 20.5 34.6 107.9 63.4 57.4 23.0 56.7 27.9 39.8 135.4 99.6 32.9 50.3 50.7 45.3 41.2 34.2 29.5 33.1 26.7 102.3 40.7 55.8 22.4 76.0 33.5 23.3 24.6 36.8 27.7 40.4 44.5 31.3 52.3 131.9 46.7 34.5 42.9 46.8 39.1 27.1 24.3 30.3 55.9 82.6 21.2 30.9 72.1 78.5 29.4 25.0 39.9 49.3 42.3 85.2 10.0 31.6 45.8 69.8 19.1 40.1 88.0 35.4 49.1 82.1 25.5 98.7 51.0 32.0 38.2 24.8 77.4 52.0 39.3 27.6 33.0 33.1 26.7 56.9 19.3 14.3 20.8 22.8 32.3 14.7 17.9 20.8 37.3 23.7 72.0 34.1 27.4 24.9 40.9 48.3 33.4 46.1 39.1 41.0 45.7 43.2 39.0 38.0 49.8 57.4 25.2 19.2 18.7 16.6 18.3 8.5 13.4 24.6 10.8 11.9 22.3 24.6 50.2 10.0 18.1 29.5 27.1 25.1 35.2 35.2 3.9 22.2 0.4 17.9 26.9 19.6 19.4 15.3 13.0 27.9 31.0 29.2 31.6 27.6 19.6 21.3 25.7 32.1 30.4 16.8 15.3 36.0 14.2 30.7 8.4 1.7 23.6 19.1 8.8 11.2 28.2 11.0 36.0 23.1 92.3 27.3 19.2 35.3 10.1 11.4 22.4 13.3 10.9 14.2 59.2 28.0 55.9 3.1 3.5 24.7 13.1 16.6 19.9 9.4 21.5 18.7 ARHGAP11B "B'-T, FAM7B1" ENSG00000285077 "Rho GTPase activating protein 11B" Q3KRB8 15 30624494-30649529 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 2.6;lymphoid tissue: 1.4" "Cell type enhanced" "Detected in many" "Early spermatids: 22.6;Erythroid cells: 37.4;Late spermatids: 21.7;Muller glia cells: 17.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 8.9;Karpas-707: 7.1" HPA064479 Uncertain Uncertain Vesicles NA NA "Cluster 20: HeLa - Mitochondria" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "HPA064479: AB_2685272" 0.2 0.0 0.0 0.8 0.2 2.6 0.2 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 1.4 0.2 0.2 0.0 0.0 0.1 0.2 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.2 0.2 0.1 0.2 0.2 0.3 0.1 1.4 0.1 0.0 0.8 0.1 0.1 1.2 1.0 2.8 1.3 0.0 0.4 0.8 3.2 0.9 1.6 1.8 0.6 1.8 1.5 0.1 0.2 0.9 1.4 1.6 0.6 1.3 3.0 3.9 3.1 8.9 0.2 0.0 2.8 1.8 0.1 0.0 0.4 0.2 0.5 0.9 1.9 0.8 7.1 1.7 1.0 1.0 2.8 0.8 0.7 1.2 1.9 3.2 0.8 0.7 1.3 1.5 0.8 1.9 0.7 0.4 0.7 1.5 1.4 1.0 2.6 1.7 0.5 0.8 1.4 0.5 3.1 0.4 3.5 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.2 0.2 0.2 0.1 0.1 0.1 0.3 0.0 1.5 1.0 6.1 2.0 1.0 2.8 1.8 3.2 0.6 0.3 0.7 0.0 0.6 1.8 6.2 0.0 5.1 7.0 0.0 0.4 22.6 0.4 1.3 1.1 0.0 37.4 0.4 0.6 0.0 2.3 15.3 0.7 1.3 6.9 4.2 0.8 0.0 3.3 0.2 8.3 2.0 7.9 3.1 21.7 2.1 3.3 0.0 1.0 4.8 17.3 4.1 0.0 0.7 0.4 2.5 1.2 12.6 1.0 1.6 0.6 1.2 2.3 0.0 1.3 1.5 15.5 12.9 6.9 1.4 0.0 5.8 1.2 12.1 0.9 ARHGAP15 BM046 ENSG00000075884 "Rho GTPase activating protein 15" Q53QZ3 2 143091362-143768352 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 79.8;lymphoid tissue: 75.2" "Cell type enhanced" "Detected in many" "B-cells: 126.3;Early spermatids: 132.3;granulocytes: 88.5;Microglial cells: 250.1;NK-cells: 89.6;T-cells: 149.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 59.4;HEL: 75.8;HL-60: 124.3;MOLT-4: 82.0;NB-4: 100.4;THP-1: 131.0;U-698: 89.5;U-937: 63.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032125 Uncertain "Nucleoplasm,Golgi apparatus,Vesicles" NA NA 38000 "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "Golgi apparatus, Vesicles" Nucleoplasm "HPA032125: AB_10671370" "unprognostic (1.59e-2)" "unprognostic (2.40e-3)" "unprognostic (8.63e-2)" "unprognostic (2.19e-2)" "unprognostic (2.99e-1)" "unprognostic (6.62e-3)" "unprognostic (6.14e-2)" "unprognostic (2.18e-3)" "unprognostic (1.32e-2)" "unprognostic (3.58e-2)" "unprognostic (2.13e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (6.95e-5)" "unprognostic (4.40e-2)" "unprognostic (2.12e-2)" "unprognostic (4.58e-2)" "unprognostic (6.94e-2)" 6.9 5.9 1.4 27.1 1.3 79.8 7.6 2.3 2.3 4.1 1.9 7.3 6.8 2.6 9.7 4.0 2.8 11.4 5.6 1.2 2.2 4.4 10.2 9.8 59.3 3.0 1.9 1.8 1.3 1.7 1.0 4.0 2.7 4.3 7.7 1.3 4.2 5.1 1.2 2.0 15.1 3.9 1.9 44.9 7.5 7.4 2.1 75.2 4.5 2.2 46.3 11.4 4.3 4.0 0.3 0.1 4.9 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 59.4 0.2 0.1 0.1 0.1 0.2 0.1 0.3 14.6 0.0 75.8 0.5 0.1 0.0 124.3 1.2 0.0 0.0 0.2 0.2 0.1 0.0 47.0 0.3 4.4 0.0 0.1 82.0 100.4 0.3 0.0 0.1 44.7 0.6 22.7 0.0 0.1 0.2 0.4 0.3 0.2 1.0 0.1 4.5 131.0 0.6 0.4 1.2 0.1 0.2 1.0 0.3 89.5 0.7 63.9 3.9 181.8 32.0 140.1 97.7 34.3 161.6 94.3 172.8 125.7 56.3 86.2 119.0 101.7 207.2 121.4 40.5 54.3 147.7 99.9 1.4 1.3 2.3 2.3 1.2 2.2 3.0 1.9 2.7 1.9 2.1 4.0 8.2 0.0 9.6 2.0 126.3 5.6 0.1 0.0 0.0 0.3 1.8 2.0 3.9 1.5 2.5 0.0 0.0 0.2 78.9 0.3 0.0 0.1 132.3 1.8 2.3 4.3 0.0 26.3 12.2 0.0 0.3 9.7 8.6 3.5 88.5 0.0 8.6 0.8 21.3 1.7 6.8 0.0 0.0 39.9 30.9 17.5 14.9 43.0 8.8 250.1 34.9 0.4 89.6 20.6 3.2 0.0 0.0 3.4 65.8 0.2 0.0 0.7 2.2 0.3 46.0 2.7 31.6 68.4 1.2 0.4 4.5 0.3 149.2 0.1 0.2 0.2 ARHGAP25 KIAA0053 ENSG00000163219 "Rho GTPase activating protein 25" P42331 2 68679601-68826833 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 72.8" "Cell type enhanced" "Detected in many" "B-cells: 88.7;granulocytes: 210.8;Microglial cells: 88.1;NK-cells: 103.0;T-cells: 53.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 657.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 66.7;HMC-1: 256.1;NB-4: 47.3;U-266/70: 50.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035346, HPA061395" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Nucleoplasm, Vesicles" "HPA035346: AB_10601116, HPA061395: AB_2684501" "unprognostic (1.13e-3)" "prognostic favorable (7.72e-4)" "unprognostic (2.45e-2)" "unprognostic (4.44e-3)" "unprognostic (8.07e-2)" "unprognostic (1.36e-2)" "unprognostic (1.13e-1)" "unprognostic (6.16e-3)" "unprognostic (2.67e-2)" "unprognostic (3.51e-2)" "unprognostic (1.00e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (1.93e-4)" "unprognostic (3.10e-1)" "unprognostic (4.26e-2)" "unprognostic (3.61e-1)" "unprognostic (4.49e-2)" 11.1 5.2 5.2 38.8 5.4 37.4 8.0 5.6 7.9 6.0 5.1 7.2 6.2 6.7 22.7 4.3 4.7 11.7 6.7 5.2 5.6 7.1 10.1 21.3 71.4 7.6 6.0 16.7 2.1 2.3 3.5 10.7 6.7 5.0 9.6 0.6 5.1 3.8 3.2 6.2 23.3 8.3 7.1 72.8 8.8 2.5 7.0 27.3 5.1 8.4 67.3 11.9 4.7 8.4 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 20.8 0.5 0.0 0.1 2.5 0.0 20.5 0.0 2.3 0.0 66.7 0.0 0.0 1.0 14.8 256.1 0.2 2.4 0.4 8.1 0.0 0.0 22.2 0.4 23.6 0.0 0.0 17.2 47.3 1.2 0.2 0.0 18.7 4.3 0.8 0.0 5.4 4.1 0.6 0.2 0.0 1.4 1.4 0.0 12.3 3.5 0.1 0.9 0.1 0.5 50.8 29.0 16.8 0.2 33.3 0.3 234.8 60.8 528.7 171.3 75.9 107.0 156.4 76.2 150.0 37.4 100.8 54.2 95.2 657.3 170.6 94.8 52.3 102.0 132.0 5.2 5.4 5.6 7.9 5.2 5.6 7.6 6.0 6.7 7.1 7.0 8.4 14.1 3.2 15.0 0.3 88.7 5.6 12.4 2.9 5.7 0.8 0.7 6.1 1.4 1.5 2.0 0.0 0.0 0.5 35.1 0.1 1.9 0.1 1.8 0.7 0.6 16.6 3.0 11.6 15.5 0.2 0.4 3.5 2.0 0.4 210.8 0.1 15.4 1.0 48.6 0.0 0.9 0.5 2.0 27.3 12.8 3.6 1.5 22.6 1.8 88.1 40.9 0.5 103.0 0.5 0.9 0.0 0.1 2.6 34.7 1.2 0.0 0.2 5.2 0.2 6.6 0.8 2.1 0.6 1.3 2.5 1.4 0.3 53.7 1.8 0.2 2.5 ARHGAP30 FLJ00267 ENSG00000186517 "Rho GTPase activating protein 30" Q7Z6I6 1 161046946-161069970 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 57.6;lymphoid tissue: 77.0" "Cell type enhanced" "Detected in many" "B-cells: 71.6;dendritic cells: 103.4;Kupffer cells: 77.8;Macrophages: 79.1;monocytes: 133.0;NK-cells: 268.8;T-cells: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 118.2;HL-60: 92.5;HMC-1: 123.4;Karpas-707: 93.1;MOLT-4: 75.8;THP-1: 90.9;U-266/70: 138.6;U-266/84: 97.7;U-698: 97.9;U-937: 72.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA036300 Enhanced Supported Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA036300: AB_10601117" "unprognostic (7.31e-2)" "unprognostic (8.83e-3)" "unprognostic (7.46e-3)" "unprognostic (1.77e-3)" "unprognostic (7.41e-2)" "unprognostic (1.68e-3)" "unprognostic (3.05e-1)" "unprognostic (6.78e-3)" "unprognostic (1.94e-2)" "unprognostic (3.89e-2)" "unprognostic (7.91e-2)" "unprognostic (3.09e-1)" "prognostic unfavorable (9.78e-4)" "unprognostic (1.18e-1)" "unprognostic (1.08e-2)" "unprognostic (6.64e-2)" "unprognostic (2.65e-2)" 12.1 4.9 3.1 55.9 3.6 57.6 5.3 3.7 4.3 3.4 3.3 8.1 9.5 2.9 2.8 14.1 4.5 10.2 2.8 2.9 3.6 3.4 6.6 25.2 77.0 6.1 4.5 2.0 2.4 1.4 1.8 7.0 5.4 3.4 8.4 0.6 6.4 2.3 2.6 19.8 23.9 8.0 5.0 75.5 11.6 2.3 6.3 63.7 2.9 2.7 61.2 13.8 6.5 6.8 0.8 0.1 0.2 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.3 1.2 118.2 0.6 0.0 0.1 2.3 0.0 0.0 0.2 55.3 0.2 39.7 0.2 0.0 0.0 92.5 123.4 0.0 1.2 0.1 0.0 0.1 0.0 56.8 0.3 93.1 0.0 1.0 75.8 21.3 0.1 0.7 0.1 46.8 0.6 1.6 0.0 1.0 0.7 0.3 0.2 0.7 0.2 0.7 0.8 90.9 0.9 0.1 0.7 0.2 0.5 138.6 97.7 97.9 0.4 72.3 0.1 7.1 29.6 33.1 32.9 32.2 25.1 11.9 21.9 27.1 21.8 12.6 17.9 25.0 48.5 19.3 46.4 15.0 23.8 33.5 3.1 3.6 3.7 4.3 2.9 3.6 6.1 4.5 5.4 5.0 6.3 6.8 1.5 3.2 20.5 0.3 71.6 5.6 3.3 6.8 0.0 0.5 5.2 2.9 1.3 2.8 13.8 0.0 4.2 0.6 103.4 0.5 0.0 3.4 2.2 6.6 1.2 2.3 0.0 14.5 0.3 6.0 1.9 1.9 3.1 13.7 68.3 0.0 6.1 1.7 55.5 0.0 0.3 0.4 8.2 77.8 44.6 0.7 0.3 79.1 5.4 14.0 133.0 0.1 268.8 0.5 1.2 12.5 0.2 0.0 49.8 5.4 0.0 0.5 15.3 3.0 0.0 1.0 1.9 0.1 0.1 9.9 24.6 4.5 105.1 0.2 0.5 16.7 ARHGAP36 FLJ30058 ENSG00000147256 "Rho GTPase activating protein 36" Q6ZRI8 X 131058346-131089885 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 22 "adrenal gland: 105.4;brain: 144.3;pituitary gland: 176.9" "Cell type enhanced" "Detected in some" "Astrocytes: 1.0;Breast glandular cells: 2.7;Oligodendrocyte precursor cells: 1.0;Skeletal myocytes: 1.5" "Cancer enriched" "Detected in some" 21 "thyroid cancer: 62.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 161 "SH-SY5Y: 176.9" "Region enhanced" "Detected in many" "hypothalamus: 89.4" "Low region specificity" "Detected in many" "HPA002064, HPA076209" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" Yes NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm "Vesicles, Plasma membrane" "HPA002064: AB_1078891, HPA076209: " "unprognostic (2.92e-2)" "unprognostic (7.71e-9)" "unprognostic (2.19e-1)" "unprognostic (8.15e-2)" "unprognostic (1.67e-1)" "unprognostic (1.78e-1)" "unprognostic (2.73e-1)" "unprognostic (1.40e-2)" "unprognostic (1.34e-2)" "unprognostic (2.31e-1)" 0.2 105.4 20.1 0.0 3.7 0.0 1.4 0.8 3.2 1.6 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 13.5 132.5 0.0 0.0 0.0 0.0 35.0 46.1 0.0 0.0 0.0 176.9 0.1 144.3 0.2 0.1 0.0 0.2 0.0 6.6 0.1 0.0 0.0 4.7 0.0 0.1 0.8 52.1 0.4 0.1 1.1 0.0 0.0 0.1 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 176.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.1 3.7 0.8 3.2 13.5 132.5 35.0 46.1 144.3 4.7 52.1 10.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ARHGEF10L "FLJ10521, KIAA1626" ENSG00000074964 "Rho guanine nucleotide exchange factor 10 like" Q9HCE6 1 17539698-17697874 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 82.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 41 "classical monocyte: 18.8;intermediate monocyte: 18.0;myeloid DC: 13.4;non-classical monocyte: 4.8" "Group enriched" "Detected in many" 48 "dendritic cells: 13.4;monocytes: 18.8" "Cell line enhanced" "Detected in many" "Hep G2: 26.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026426, HPA026440, HPA028115" Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus, Vesicles, Cytosol" "HPA026426: AB_10599487, HPA026440: AB_10599422, HPA028115: AB_10602285" "unprognostic (4.34e-2)" "unprognostic (1.35e-1)" "unprognostic (1.13e-2)" "unprognostic (2.59e-1)" "unprognostic (1.03e-1)" "prognostic favorable (8.13e-5)" "unprognostic (3.61e-2)" "unprognostic (7.90e-2)" "unprognostic (2.10e-2)" "unprognostic (1.75e-3)" "unprognostic (1.94e-3)" "unprognostic (5.83e-2)" "prognostic favorable (5.65e-4)" "unprognostic (4.11e-2)" "unprognostic (1.66e-1)" "unprognostic (8.17e-2)" "unprognostic (5.21e-3)" 22.2 10.5 11.9 11.4 10.9 1.7 16.5 38.7 11.4 24.2 13.8 29.4 15.9 16.2 4.6 28.1 16.0 11.9 30.2 10.3 12.2 32.5 87.5 13.0 4.5 19.4 18.5 10.4 43.9 17.0 7.9 5.9 19.4 18.4 12.9 4.0 25.9 19.5 66.2 40.9 21.7 8.7 10.9 9.7 20.8 3.7 17.7 1.6 18.0 35.5 4.3 24.6 21.7 9.3 8.0 9.1 11.3 3.9 19.1 6.3 7.6 5.4 10.6 6.3 5.3 9.5 23.6 0.0 9.8 10.2 8.8 6.0 1.6 2.9 1.2 0.2 2.9 0.0 9.5 26.9 4.2 0.0 0.0 8.5 5.5 3.9 1.1 12.7 1.2 0.0 0.0 0.2 17.8 7.7 0.0 0.2 4.9 12.2 0.0 0.0 4.5 3.0 13.4 16.4 16.5 12.2 4.2 2.9 12.3 3.2 11.0 9.5 0.0 5.5 6.5 6.5 2.3 0.0 2.5 0.0 8.5 0.2 3.0 0.0 18.8 0.0 0.0 18.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.0 0.3 0.0 4.8 0.0 0.0 7.6 11.9 10.9 38.7 11.4 10.3 12.2 19.4 18.5 19.4 10.9 17.7 9.3 1.3 3.2 7.4 82.6 1.0 5.7 5.3 7.2 5.2 16.1 13.7 12.3 36.4 20.0 13.9 31.3 2.1 0.7 0.1 41.6 9.8 19.8 15.9 3.4 4.2 2.1 37.8 2.7 16.7 20.3 0.6 8.5 17.9 6.5 0.0 3.9 2.5 43.7 26.0 10.1 23.8 45.5 8.2 8.6 26.4 8.9 5.0 18.6 3.6 19.7 9.6 14.6 0.0 24.6 7.1 11.7 24.9 6.8 0.2 5.9 13.6 18.3 9.4 5.4 13.1 10.8 18.3 11.9 1.6 8.0 8.7 1.0 0.6 0.3 46.1 12.1 ARHGEF33 ENSG00000214694 "Rho guanine nucleotide exchange factor 33" A8MVX0 2 38889875-38975454 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.6" "Cell type enhanced" "Detected in many" "Early spermatids: 34.8;Excitatory neurons: 15.2;Late spermatids: 26.8;Spermatocytes: 34.7;Spermatogonia: 35.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "eosinophil: 3.6" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.6" "Group enriched" "Detected in some" 4 "BEWO: 5.6;HeLa: 2.6;SiHa: 7.2" "Region enriched" "Detected in many" 32 "cerebellum: 280.4" "Region enriched" "Detected in all" 6 "cerebellum: 23.1" "HPA034661, HPA041051" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Vesicles "Nucleoplasm, Cytosol" "HPA034661: AB_10669679, HPA041051: AB_2677274" "unprognostic (8.38e-2)" "unprognostic (7.05e-4)" "unprognostic (1.95e-1)" "unprognostic (4.67e-2)" "unprognostic (1.35e-1)" "unprognostic (1.49e-3)" "unprognostic (1.49e-1)" "unprognostic (3.66e-1)" "unprognostic (3.37e-1)" "unprognostic (5.82e-2)" "unprognostic (2.05e-3)" "unprognostic (4.99e-1)" "unprognostic (4.12e-2)" "unprognostic (6.14e-2)" "unprognostic (1.56e-1)" "unprognostic (2.42e-1)" "unprognostic (1.99e-1)" 0.4 2.1 4.9 0.6 5.2 0.0 0.9 22.6 5.8 1.5 4.4 1.0 0.1 1.5 2.6 0.4 1.4 0.8 0.5 4.9 4.1 0.9 0.2 0.7 0.3 4.1 5.4 3.5 0.4 0.7 3.4 0.5 4.0 0.9 0.3 4.0 0.5 0.7 0.3 0.8 0.4 0.5 3.1 0.3 0.5 5.7 7.2 0.1 1.1 0.0 0.2 0.7 0.7 5.0 0.2 0.0 0.2 0.1 0.1 0.1 5.6 0.5 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.2 0.6 0.1 2.6 0.1 0.4 0.2 0.1 0.5 0.6 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.3 0.3 0.2 7.2 0.3 0.0 0.6 0.0 0.2 0.4 0.1 0.9 0.0 0.1 0.3 0.2 0.0 0.1 0.1 0.1 0.0 0.2 3.6 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 4.9 5.2 22.6 5.8 4.9 4.1 4.1 5.4 4.0 3.1 7.2 5.0 0.4 0.0 1.5 7.8 0.1 0.0 0.1 0.0 0.6 2.5 0.3 0.6 0.8 1.5 0.6 0.0 0.0 1.1 0.0 0.1 0.0 0.1 34.8 1.8 1.2 0.4 0.0 2.7 15.2 0.0 1.9 1.2 0.0 0.2 0.0 1.4 0.0 0.2 1.0 0.0 11.4 0.4 0.0 0.0 0.0 26.8 1.2 0.2 0.0 1.9 0.1 3.6 0.0 5.5 3.4 0.0 0.0 3.4 0.0 0.1 0.0 0.4 3.9 2.9 0.0 0.3 1.5 34.7 35.6 0.1 0.1 0.5 0.0 2.0 0.1 0.2 ARL14EP "ARF7EP, C11orf46, FLJ38968" ENSG00000152219 "ADP ribosylation factor like GTPase 14 effector protein" Q8N8R7 11 30323104-30338223 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 130.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039634, HPA048127" Approved Supported "Nucleoplasm,Vesicles,Focal adhesion sites,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Vesicles, Focal adhesion sites, Cytosol" Nucleoplasm "HPA039634: AB_2676606, HPA048127: AB_2680277" "prognostic favorable (2.50e-5)" "unprognostic (8.93e-2)" "unprognostic (6.19e-3)" "unprognostic (1.34e-1)" "unprognostic (1.67e-1)" "unprognostic (3.09e-1)" "prognostic unfavorable (5.26e-4)" "unprognostic (2.50e-2)" "unprognostic (6.50e-3)" "unprognostic (5.76e-2)" "unprognostic (8.86e-2)" "unprognostic (1.04e-1)" "unprognostic (8.57e-3)" "unprognostic (1.60e-1)" "unprognostic (3.47e-1)" "unprognostic (4.50e-2)" "prognostic favorable (7.49e-4)" 13.9 22.5 13.5 13.2 15.6 8.0 20.0 15.9 17.3 17.0 14.9 11.8 9.5 18.9 23.2 11.6 16.4 13.1 22.9 15.7 14.2 17.4 19.7 10.9 22.5 12.4 13.3 20.5 12.9 26.1 12.0 11.5 12.1 19.7 10.8 15.9 19.1 19.9 20.6 12.6 9.7 14.5 13.9 20.8 15.7 14.6 13.3 15.6 24.7 20.8 21.4 14.5 8.1 13.8 10.8 15.4 16.9 14.8 27.1 29.2 8.5 20.8 26.0 18.4 20.2 8.5 4.1 43.8 13.9 15.0 20.5 17.8 24.8 17.5 25.9 35.2 30.7 13.3 12.0 15.0 42.6 24.0 14.7 30.5 34.7 8.7 32.8 26.7 20.6 17.9 21.4 23.2 32.5 10.4 21.9 19.6 19.6 24.1 21.3 18.8 41.2 18.0 24.7 14.8 19.2 20.4 16.2 21.4 25.8 15.0 22.8 13.4 18.1 20.8 11.2 41.7 20.1 36.0 21.9 28.5 20.0 14.8 20.4 12.7 19.2 6.4 23.3 20.0 55.5 35.9 28.2 25.9 26.3 28.9 25.7 25.0 3.5 52.9 15.5 18.9 20.3 23.1 13.5 15.6 15.9 17.3 15.7 14.2 12.4 13.3 12.1 13.9 13.3 13.8 27.3 28.9 33.6 14.4 39.7 12.4 46.6 35.1 8.0 34.0 19.9 30.4 68.1 24.3 23.8 25.8 14.6 19.1 29.2 5.9 76.3 27.3 130.1 25.8 41.0 29.2 14.5 13.2 31.1 22.5 12.7 33.4 12.8 19.0 27.8 33.5 15.4 29.8 25.7 32.0 26.4 11.7 32.6 27.1 29.3 66.3 27.4 28.4 26.6 18.7 45.4 36.1 38.1 27.6 19.9 21.9 8.4 25.2 25.4 46.0 9.4 42.1 27.5 32.4 13.1 33.1 29.8 111.4 37.6 13.8 11.1 11.1 29.6 33.0 12.6 28.4 ARL4D ARF4L ENSG00000175906 "ADP ribosylation factor like GTPase 4D" P49703 17 43398993-43401137 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 224.3;Early spermatids: 220.8;Rod photoreceptor cells: 259.6;Squamous epithelial cells: 223.4;Suprabasal keratinocytes: 254.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 32.3;naive B-cell: 36.1" "Lineage enriched" "Detected in all" 4 "B-cells: 36.1" "Cell line enhanced" "Detected in many" "HHSteC: 57.1;hTCEpi: 76.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basal ganglia: 8.7;cerebral cortex: 8.8;hippocampal formation: 5.7;olfactory bulb: 4.2;spinal cord: 5.4" HPA060379 Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "Golgi apparatus" "HPA060379: AB_2684269" "unprognostic (9.53e-3)" "unprognostic (1.65e-1)" "unprognostic (2.34e-2)" "prognostic favorable (1.16e-5)" "unprognostic (7.71e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (2.47e-1)" "unprognostic (4.59e-2)" "unprognostic (4.45e-1)" "unprognostic (1.25e-1)" "unprognostic (3.37e-2)" "unprognostic (7.87e-2)" "unprognostic (2.00e-3)" "unprognostic (3.49e-2)" "unprognostic (6.48e-2)" "unprognostic (1.27e-3)" "prognostic unfavorable (9.25e-4)" 21.0 4.3 7.9 2.2 8.7 0.9 7.2 9.1 11.6 29.3 12.6 27.9 2.0 20.2 4.7 82.2 22.1 7.3 12.7 8.1 7.1 30.5 56.4 16.2 1.6 5.6 5.7 9.7 2.2 8.1 21.6 7.7 5.7 11.0 3.5 85.1 16.9 15.2 1.9 44.9 6.0 14.8 5.4 16.7 7.6 32.1 5.7 1.6 38.3 3.4 3.0 28.5 39.5 9.3 8.7 10.9 6.7 5.2 12.5 17.2 3.1 21.0 21.5 14.6 18.8 9.7 37.7 0.1 10.3 22.6 10.0 23.4 4.5 32.0 10.0 1.9 7.5 0.7 8.7 22.5 57.1 2.4 2.1 19.2 76.1 21.3 45.8 13.2 6.3 2.3 1.4 0.4 14.3 0.5 5.4 5.0 7.1 0.8 10.1 9.1 1.5 1.0 24.9 18.8 7.9 5.6 16.5 0.4 15.8 14.4 30.6 8.5 1.3 21.0 6.7 27.2 6.4 2.1 1.1 0.0 25.8 1.9 7.1 0.1 2.8 2.1 5.1 4.3 3.2 32.3 4.2 4.7 8.4 36.1 4.6 5.2 0.0 2.1 1.4 2.5 1.0 4.6 7.9 8.7 9.1 11.6 8.1 7.1 5.6 5.7 5.7 5.4 5.7 9.3 28.8 0.0 1.7 0.7 37.9 224.3 41.4 142.2 132.1 155.5 35.3 60.6 12.7 5.7 49.5 132.4 116.7 39.9 37.4 1.5 76.3 2.3 220.8 55.5 33.3 32.2 11.9 4.0 9.1 1.8 24.1 52.3 5.6 69.6 0.0 20.7 22.9 29.7 8.1 16.8 9.3 5.4 26.4 4.1 77.9 55.3 15.8 16.6 26.6 1.0 1.4 70.1 2.1 2.5 1.3 3.7 0.9 22.6 1.4 9.5 0.3 17.6 7.6 259.6 13.1 11.1 45.1 25.0 9.2 223.4 254.6 105.5 31.7 19.3 4.6 78.1 ARMC8 "DKFZP434A043, GID5, HSPC056, VID28" ENSG00000114098 "Armadillo repeat containing 8" Q8IUR7 3 138187248-138298384 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 128.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036996, HPA044869" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "Vesicles, Cytosol" "HPA036996: AB_10672786, HPA044869: AB_2679123" "unprognostic (2.04e-1)" "unprognostic (1.60e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.05e-4)" "unprognostic (3.51e-2)" "unprognostic (2.39e-2)" "prognostic unfavorable (8.90e-5)" "unprognostic (1.96e-1)" "unprognostic (2.04e-2)" "unprognostic (7.48e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (2.15e-4)" "unprognostic (3.27e-2)" "unprognostic (2.03e-1)" "unprognostic (4.06e-2)" "unprognostic (5.51e-2)" "unprognostic (1.18e-1)" 20.8 14.3 14.6 18.0 16.6 60.6 16.4 41.2 18.5 14.7 25.6 16.8 12.0 17.6 12.2 21.0 15.7 15.3 17.4 13.3 16.9 18.9 16.9 16.3 21.2 16.0 15.8 16.0 14.2 21.3 12.3 19.8 17.5 16.5 18.3 26.2 12.5 17.5 38.7 12.8 13.5 24.4 15.9 15.9 15.4 18.4 16.7 22.2 21.3 34.8 22.9 22.2 13.4 19.4 46.2 22.0 28.5 23.2 35.2 30.7 37.9 34.8 33.4 46.7 45.3 34.3 23.7 43.2 35.0 30.2 54.6 23.5 37.1 33.9 57.4 29.3 25.7 77.2 14.3 23.9 44.3 60.6 82.5 46.2 21.2 30.0 42.9 25.4 37.0 37.0 29.3 23.8 58.6 40.5 42.7 28.6 39.2 34.8 19.1 33.0 45.7 34.6 30.7 42.3 33.0 24.0 50.0 17.2 29.1 36.8 33.8 31.6 40.4 24.8 20.2 33.1 25.9 45.0 37.5 65.2 22.4 28.4 25.2 79.7 39.7 74.8 38.6 43.5 44.6 48.8 35.2 41.1 45.9 43.3 41.1 40.6 27.9 48.8 46.0 20.3 50.4 37.4 14.6 16.6 41.2 18.5 13.3 16.9 16.0 15.8 17.5 15.9 16.7 19.4 25.0 28.9 14.1 56.2 38.2 31.0 31.9 29.0 25.0 34.9 17.7 14.9 23.1 24.3 27.2 12.9 33.3 29.9 35.6 25.1 11.7 20.2 7.3 16.2 22.3 23.4 23.4 59.6 101.9 14.6 27.6 23.4 31.1 19.5 35.4 24.1 24.3 24.6 22.5 43.7 93.6 16.9 30.5 32.7 39.2 7.3 30.4 35.2 19.6 70.3 27.2 25.0 39.1 128.2 120.8 14.8 17.2 22.2 26.8 28.1 17.0 26.1 17.4 47.0 13.1 30.2 31.5 43.4 32.2 22.3 28.4 34.1 30.9 19.6 17.4 28.3 ARMCX4 "CXorf35, GASP4, MGC40053" ENSG00000196440 "Armadillo repeat containing X-linked 4" Q5H9R4 X 101418287-101533459 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 66.6;Excitatory neurons: 59.1;Inhibitory neurons: 87.5;Microglial cells: 63.7;Oligodendrocyte precursor cells: 78.4;Oligodendrocytes: 75.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000429, HPA051930" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Vesicles "HPA000429: AB_1078210, HPA051930: AB_2681665" "unprognostic (1.92e-1)" "unprognostic (1.91e-1)" "unprognostic (1.07e-2)" "unprognostic (1.10e-2)" "unprognostic (6.91e-3)" "unprognostic (2.81e-3)" "unprognostic (7.28e-2)" "unprognostic (3.67e-4)" "unprognostic (2.33e-2)" "unprognostic (4.29e-1)" "prognostic favorable (8.20e-5)" "unprognostic (1.94e-2)" "unprognostic (1.40e-2)" "unprognostic (6.94e-3)" "unprognostic (1.69e-1)" "unprognostic (1.88e-1)" "unprognostic (4.92e-2)" 2.1 4.0 1.8 1.1 2.1 0.7 2.7 1.4 2.0 2.8 0.0 2.5 0.9 3.6 2.5 1.0 3.0 1.3 1.8 2.0 3.0 2.4 1.0 1.8 0.9 1.8 2.1 7.1 2.0 4.5 4.5 1.7 2.1 3.6 1.6 1.6 1.9 4.7 1.9 2.1 2.1 2.6 1.1 1.7 1.8 0.9 2.2 0.9 2.7 1.0 0.8 2.3 1.8 2.3 2.4 0.6 7.9 0.0 3.7 3.9 0.8 5.5 4.3 4.4 8.5 1.9 0.7 0.0 2.1 8.2 0.1 0.9 0.0 0.1 7.2 0.0 0.9 0.6 2.5 0.0 2.2 0.0 3.0 2.4 0.4 9.6 0.0 0.0 7.8 0.0 0.0 0.7 2.0 0.0 0.3 0.3 5.8 0.8 0.0 0.4 6.5 0.0 1.1 1.4 5.3 4.9 0.8 0.0 3.0 1.3 0.6 1.2 2.9 2.0 1.2 6.1 0.0 0.0 0.0 0.0 3.7 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.1 1.4 2.0 2.0 3.0 1.8 2.1 2.1 1.1 2.2 2.3 8.7 3.2 6.8 66.6 2.2 2.4 7.7 1.7 5.7 24.5 9.1 7.1 10.5 2.8 7.9 27.6 8.4 1.7 2.6 2.3 17.6 2.7 0.2 5.6 8.9 8.0 3.0 1.3 59.1 2.3 0.7 11.0 2.0 8.3 3.8 13.3 5.3 2.5 2.3 23.5 87.5 2.3 6.1 3.8 5.1 0.7 10.5 2.4 17.8 63.7 2.8 11.6 4.1 78.4 75.6 2.0 3.9 12.4 2.2 5.3 4.7 4.8 9.8 7.8 0.0 8.1 10.9 1.3 1.3 1.8 3.4 1.5 2.2 8.4 4.0 4.5 ARMH3 "C10orf76, FLJ13114" ENSG00000120029 "Armadillo like helical domain containing 3" Q5T2E6 10 101845599-102056193 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 11.2;dendritic cells: 10.5;Extravillous trophoblasts: 14.8;Granulosa cells: 11.5;Hofbauer cells: 12.6;Syncytiotrophoblasts: 16.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050913, HPA053580" Approved Approved Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 23: Testis - Cell cycle regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA050913: AB_2681270, HPA053580: AB_2682198" "unprognostic (5.88e-2)" "unprognostic (1.33e-1)" "unprognostic (1.62e-1)" "unprognostic (3.41e-2)" "unprognostic (9.41e-2)" "unprognostic (9.55e-2)" "unprognostic (5.28e-2)" "unprognostic (1.92e-2)" "unprognostic (1.18e-1)" "unprognostic (6.03e-3)" "unprognostic (1.40e-3)" "unprognostic (2.76e-1)" "unprognostic (1.86e-2)" "unprognostic (1.16e-1)" "unprognostic (2.48e-1)" "unprognostic (3.85e-1)" "unprognostic (4.87e-2)" 10.4 9.1 5.9 12.0 7.6 21.8 9.9 10.2 7.3 11.2 8.0 12.5 12.8 10.5 9.4 14.3 10.5 9.2 16.6 5.7 7.3 10.0 12.0 11.8 12.7 7.1 8.2 11.2 10.1 16.4 7.9 11.0 6.1 10.8 13.2 16.3 9.5 10.5 19.7 12.2 12.2 12.9 6.0 13.6 10.3 8.9 6.7 13.1 10.0 19.8 13.3 10.8 10.1 7.9 23.2 17.7 15.5 19.1 12.9 17.3 13.9 20.3 24.0 20.0 16.9 12.2 18.6 17.0 13.5 22.9 14.5 17.7 20.4 22.4 18.3 17.9 18.9 30.3 15.9 14.6 15.2 21.3 26.4 16.0 17.7 22.6 19.9 23.4 15.3 15.3 0.9 15.9 16.6 14.4 16.5 13.8 8.5 18.8 11.6 16.0 28.1 11.0 16.4 18.6 7.3 12.1 15.8 10.9 21.0 15.8 28.8 12.4 15.1 10.5 17.1 9.8 14.7 15.4 17.0 17.1 16.9 23.7 7.9 19.4 7.3 7.4 5.9 8.7 5.5 6.1 6.2 4.5 7.7 7.0 4.8 4.9 1.9 5.2 10.7 7.4 6.0 4.7 5.9 7.6 10.2 7.3 5.7 7.3 7.1 8.2 6.1 6.0 6.7 7.9 8.8 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 7.4 6.0 0.0 0.0 0.0 0.0 0.0 11.2 10.5 0.0 1.9 7.8 0.0 6.9 6.8 1.9 0.0 0.0 0.0 9.7 14.8 2.7 0.0 7.7 0.0 11.5 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 9.9 0.0 0.0 2.2 0.0 0.0 7.6 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 16.3 3.9 5.7 0.0 0.0 ARNTL "bHLHe5, BMAL1, JAP3, MOP3, PASD3" ENSG00000133794 "Aryl hydrocarbon receptor nuclear translocator like" O00327 11 13276652-13387266 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 63.6" "Cancer enhanced" "Detected in all" "thyroid cancer: 11.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB045962, HPA050938" Supported Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Vesicles "CAB045962: AB_11124144, HPA050938: AB_2681282" "unprognostic (1.89e-1)" "unprognostic (1.95e-1)" "unprognostic (1.95e-2)" "unprognostic (1.63e-1)" "unprognostic (9.00e-2)" "unprognostic (1.77e-1)" "unprognostic (3.72e-1)" "unprognostic (3.76e-2)" "unprognostic (8.92e-2)" "unprognostic (2.86e-2)" "unprognostic (3.16e-1)" "unprognostic (7.80e-2)" "unprognostic (1.34e-2)" "unprognostic (2.10e-1)" "unprognostic (2.77e-2)" "unprognostic (3.11e-2)" "unprognostic (7.08e-2)" 15.0 13.3 3.2 5.1 4.8 7.4 14.1 4.8 8.3 10.5 3.2 12.4 5.2 11.6 1.6 10.5 11.5 4.0 9.5 5.5 1.9 7.2 19.4 15.0 5.8 1.6 2.6 19.7 10.3 1.5 12.3 4.4 2.2 8.5 4.1 23.4 12.7 3.4 27.0 17.6 12.4 5.6 1.9 11.6 10.9 10.9 4.4 14.1 18.9 8.2 6.4 9.3 11.5 7.4 8.2 9.0 7.5 4.0 15.0 9.0 5.7 9.5 8.1 8.6 9.7 3.7 10.9 0.1 2.6 5.2 10.4 3.4 5.3 10.3 7.7 13.6 6.3 3.9 6.6 1.8 23.7 1.8 16.2 10.1 21.3 3.7 14.1 5.9 6.2 12.6 2.5 14.9 6.9 4.7 4.7 0.9 1.6 5.4 4.3 5.1 11.4 3.4 5.7 1.8 1.2 12.2 6.1 0.7 7.6 7.1 5.7 7.0 11.5 6.2 6.8 20.3 5.5 4.1 12.0 0.0 6.4 4.1 8.3 4.3 8.3 17.9 18.1 9.0 25.2 2.6 16.8 15.6 8.4 3.1 9.4 11.1 24.5 14.1 8.9 1.1 11.1 10.7 3.2 4.8 4.8 8.3 5.5 1.9 1.6 2.6 2.2 1.9 4.4 7.4 4.9 25.6 21.0 49.9 9.0 30.8 13.4 7.3 10.2 28.3 6.1 5.0 8.8 10.0 11.1 1.8 16.7 17.6 34.8 8.6 17.6 6.8 1.5 6.1 14.2 6.6 1.2 3.0 63.6 6.4 2.2 10.3 11.7 12.9 2.5 6.9 10.8 22.9 8.2 30.3 30.5 4.6 4.1 14.0 12.3 4.2 12.8 11.9 3.6 18.7 13.1 18.8 32.0 34.2 11.9 8.3 9.3 19.9 11.5 8.0 13.5 11.3 5.3 30.9 13.1 6.6 10.7 4.7 5.4 9.4 32.4 6.3 33.0 4.7 4.5 12.0 ARPC1B "ARC41, p40-ARC, p41-ARC" ENSG00000130429 "Actin related protein 2/3 complex subunit 1B" O15143 7 99374249-99394816 "Disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 317.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 948.7;Hofbauer cells: 1088.1;Kupffer cells: 1035.5;monocytes: 1029.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 899.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004832 Enhanced Supported Vesicles,Cytosol NA NA 13000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 51: Myeloid cells - Hemostasis" "Vesicles, Cytosol" "HPA004832: AB_1845044" "unprognostic (5.94e-2)" "unprognostic (2.40e-2)" "unprognostic (2.84e-3)" "unprognostic (2.47e-2)" "unprognostic (1.43e-2)" "unprognostic (2.69e-2)" "prognostic unfavorable (2.57e-4)" "unprognostic (4.37e-2)" "unprognostic (7.76e-2)" "unprognostic (1.02e-2)" "unprognostic (1.56e-1)" "unprognostic (4.86e-1)" "prognostic unfavorable (1.62e-6)" "unprognostic (1.18e-1)" "unprognostic (1.87e-2)" "unprognostic (1.24e-1)" "unprognostic (7.27e-2)" 132.2 71.6 19.6 173.3 20.4 209.8 99.1 20.5 25.9 71.7 23.9 104.4 106.6 71.0 14.2 51.6 73.9 48.9 70.1 18.2 21.7 84.4 81.7 169.5 202.1 28.9 23.5 30.1 51.4 14.3 52.4 66.4 26.8 67.4 32.5 1.1 72.4 30.1 18.6 43.2 160.2 39.4 27.3 317.3 66.2 20.4 33.3 62.2 90.1 19.5 95.5 85.1 57.5 28.4 124.3 219.3 16.1 47.5 62.9 225.0 167.9 165.8 170.5 68.7 60.5 146.3 477.8 215.4 308.2 188.5 146.9 93.1 22.4 152.5 27.5 175.5 59.9 157.0 61.6 98.4 179.7 159.5 515.8 125.7 77.3 96.2 94.3 134.6 181.5 113.3 177.9 508.0 100.2 574.5 158.8 332.5 59.6 148.9 435.5 139.5 14.6 536.2 141.2 59.7 13.2 42.1 116.4 506.3 899.5 54.4 119.7 322.4 262.0 190.1 155.8 339.0 216.6 91.4 190.1 263.5 189.9 411.0 350.4 1026.1 2400.1 1973.2 770.3 2458.8 723.9 786.7 883.0 857.2 2054.4 699.1 510.2 680.0 1963.4 633.5 2382.6 1172.9 1315.9 4198.2 19.6 20.4 20.5 25.9 18.2 21.7 28.9 23.5 26.8 27.3 33.3 28.4 182.2 41.7 86.6 1.0 279.2 60.5 141.3 587.9 58.1 9.6 50.8 34.3 9.1 107.2 260.2 130.6 8.4 588.4 416.3 264.9 25.4 407.1 3.2 37.7 37.2 265.5 112.7 84.9 3.2 414.5 948.7 99.7 62.7 41.3 192.2 31.0 226.3 54.5 1088.1 1.7 2.3 97.6 203.4 1035.5 422.8 8.4 37.3 789.1 179.7 28.1 1029.7 21.4 498.5 0.5 1.6 405.1 268.7 18.0 154.0 132.4 516.0 110.9 214.0 14.7 92.1 29.5 238.5 2.7 15.5 26.3 37.1 303.2 324.4 20.4 161.1 187.6 ARPC5 "ARC16, dJ127C7.3, p16-Arc" ENSG00000162704 "Actin related protein 2/3 complex subunit 5" O15511 1 183620846-183635783 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022013, HPA031972" Approved Approved "Vesicles,Plasma membrane,Cell Junctions,Cytosol" NA NA 3300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" "Vesicles, Plasma membrane, Cell Junctions, Cytosol" "HPA022013: AB_1845045, HPA031972: " "unprognostic (3.82e-1)" "unprognostic (8.78e-2)" "unprognostic (1.43e-1)" "unprognostic (2.36e-2)" "unprognostic (1.74e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (3.63e-4)" "unprognostic (5.90e-3)" "unprognostic (3.84e-2)" "unprognostic (3.17e-3)" "unprognostic (1.14e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.21e-10)" "unprognostic (3.03e-2)" "unprognostic (4.66e-2)" "unprognostic (1.49e-2)" "unprognostic (2.48e-1)" 86.1 49.2 17.4 148.2 22.5 69.1 48.8 23.7 23.8 46.5 13.0 104.7 99.5 69.5 15.7 77.8 52.0 52.9 35.7 20.0 22.3 39.0 64.3 103.1 158.9 35.2 22.8 30.6 51.7 29.9 19.7 108.2 29.7 46.0 68.9 8.0 45.9 35.9 18.7 42.6 117.4 78.9 24.0 120.8 88.6 38.4 24.1 130.5 46.0 22.5 131.3 75.9 51.8 37.8 313.4 167.7 141.0 98.1 114.0 161.5 338.7 419.7 317.9 176.3 143.0 150.9 215.9 284.9 463.9 241.7 114.6 211.2 101.1 141.6 93.9 413.6 87.1 172.9 212.6 132.6 185.2 254.8 325.0 197.6 148.2 215.7 170.3 201.2 213.7 196.1 133.3 229.1 233.9 125.6 238.5 67.9 133.7 238.5 63.0 219.2 126.3 278.6 97.3 158.7 61.1 164.7 435.8 186.1 167.3 147.1 185.2 222.5 480.9 259.0 134.5 293.8 410.1 270.1 321.8 196.2 204.5 179.6 204.6 1221.0 987.7 1563.7 395.7 1110.1 315.7 338.3 382.3 407.1 838.9 339.7 409.4 415.4 1852.1 392.6 1267.7 394.3 512.4 1913.3 17.4 22.5 23.7 23.8 20.0 22.3 35.2 22.8 29.7 24.0 24.1 37.8 148.7 375.0 188.9 8.1 163.3 249.1 178.3 275.9 91.0 34.2 79.9 118.9 30.2 150.2 197.6 82.8 14.6 475.1 227.4 283.5 166.3 344.3 35.5 78.8 211.4 186.7 202.0 90.0 21.6 280.2 734.2 166.2 87.1 119.8 258.8 147.7 181.7 87.4 608.5 38.7 13.8 146.6 238.0 556.3 740.8 24.2 125.9 558.5 254.3 20.6 635.1 56.7 423.3 7.5 51.5 381.6 234.5 183.6 132.1 182.6 213.6 152.0 95.2 25.4 243.3 83.9 286.8 151.9 137.3 161.5 244.9 199.5 234.4 144.4 155.4 234.6 ARPIN-AP3S2 C15orf38-AP3S2 ENSG00000250021 "ARPIN-AP3S2 readthrough" 15 89834308-89912882 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA040513, HPA047173, HPA049270, HPA052278" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" Vesicles "HPA040513: AB_2677015, HPA047173: AB_2679969, HPA049270: AB_2680696, HPA052278: AB_2681783" "unprognostic (1.27e-1)" "unprognostic (8.88e-2)" "unprognostic (4.94e-2)" "unprognostic (1.04e-1)" "unprognostic (3.25e-2)" "unprognostic (3.44e-1)" "unprognostic (2.56e-1)" "unprognostic (1.80e-1)" "unprognostic (1.84e-1)" "unprognostic (2.19e-1)" "unprognostic (1.82e-1)" "unprognostic (1.42e-1)" "unprognostic (1.44e-2)" "unprognostic (1.27e-1)" "unprognostic (8.35e-2)" "unprognostic (2.29e-1)" "unprognostic (4.49e-2)" 12.3 12.8 12.4 7.9 14.1 5.9 11.5 14.5 13.3 9.2 10.7 14.6 10.4 9.1 11.4 12.8 9.1 8.1 19.4 11.2 14.2 13.9 23.4 10.2 5.8 14.6 15.1 10.6 20.3 10.9 10.2 9.3 15.0 11.0 15.0 10.9 10.3 8.7 22.0 10.3 9.6 9.4 13.2 9.5 9.4 12.0 15.0 9.0 11.2 15.2 8.0 11.0 10.0 14.9 11.7 25.0 19.5 26.1 27.7 12.5 13.9 20.3 22.8 25.5 25.5 8.1 26.8 6.2 20.8 17.1 21.6 14.2 15.9 17.8 17.2 12.6 14.7 8.6 11.2 18.4 16.1 4.2 6.6 15.2 14.7 15.1 15.2 13.8 23.0 7.5 8.3 14.4 19.8 16.6 6.4 7.0 20.2 29.7 6.0 5.0 7.7 4.1 24.4 13.3 6.1 9.9 36.3 35.2 27.9 25.1 23.3 8.9 11.8 22.6 16.8 31.4 13.0 4.6 13.0 6.6 19.1 5.6 17.0 13.1 26.7 11.8 6.8 23.1 9.1 7.2 8.4 7.5 20.0 6.8 6.2 6.2 18.7 10.9 16.8 8.4 9.3 16.9 12.4 14.1 14.5 13.3 11.2 14.2 14.6 15.1 15.0 13.2 15.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ARRDC4 FLJ36045 ENSG00000140450 "Arrestin domain containing 4" Q8NCT1 15 97960703-97973833 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 82.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 105.7;Paneth cells: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 1.1;classical monocyte: 2.5;eosinophil: 1.5;intermediate monocyte: 1.7;myeloid DC: 1.1;neutrophil: 1.4" "Group enriched" "Detected in many" 8 "dendritic cells: 1.1;granulocytes: 1.5;monocytes: 2.5" "Cell line enhanced" "Detected in many" "BJ: 103.2;HSkMC: 55.8;hTCEpi: 86.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039934, HPA042109" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Vesicles "HPA039934: , HPA042109: AB_10795606" "unprognostic (2.13e-1)" "unprognostic (1.10e-1)" "unprognostic (2.32e-1)" "unprognostic (5.60e-3)" "unprognostic (4.49e-3)" "unprognostic (8.23e-2)" "unprognostic (1.16e-2)" "unprognostic (2.78e-1)" "unprognostic (7.65e-2)" "unprognostic (1.10e-1)" "unprognostic (1.01e-2)" "unprognostic (1.42e-2)" "unprognostic (2.02e-3)" "unprognostic (2.90e-2)" "unprognostic (1.65e-1)" "unprognostic (3.04e-2)" "unprognostic (6.77e-2)" 12.5 12.2 21.6 16.5 24.6 11.5 19.8 24.1 22.4 16.2 16.9 43.9 15.8 14.6 15.6 10.0 14.5 17.2 12.1 30.5 39.1 25.1 30.2 19.8 7.5 76.6 24.1 7.3 34.7 6.3 8.9 18.3 73.9 10.9 23.0 4.5 8.1 16.4 14.8 35.5 22.6 18.1 45.9 8.0 26.9 14.7 20.5 5.7 17.3 9.6 5.1 14.9 10.8 82.8 5.8 0.2 0.8 15.0 6.6 47.7 0.0 103.2 45.8 13.5 6.0 6.2 3.6 0.0 14.2 4.8 1.2 6.0 3.7 36.0 21.6 0.0 9.6 10.1 1.9 4.1 2.6 7.0 15.2 55.8 86.9 15.4 17.9 18.8 0.7 2.9 14.4 0.0 4.9 19.2 1.2 5.8 3.0 17.4 2.1 0.1 0.9 0.2 26.3 12.7 5.0 8.8 15.7 5.7 29.5 3.1 2.1 10.6 0.1 4.0 2.9 21.2 5.0 0.0 0.0 0.2 8.7 1.2 10.6 1.1 2.5 1.5 0.0 1.7 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.0 1.4 0.0 0.2 0.2 0.0 0.4 21.6 24.6 24.1 22.4 30.5 39.1 76.6 24.1 73.9 45.9 20.5 82.8 5.7 3.2 10.4 19.9 4.0 25.4 3.1 11.0 23.9 1.6 14.4 8.3 12.9 8.6 9.4 22.0 6.2 0.3 1.4 105.7 7.9 2.7 4.5 21.5 17.6 5.9 38.3 4.4 8.1 8.2 0.2 12.3 15.8 18.0 23.5 1.4 6.4 17.1 21.5 0.0 6.0 29.5 10.2 23.9 10.5 10.9 5.0 19.7 24.9 3.7 13.4 0.7 3.1 38.7 3.4 12.0 82.4 8.2 0.2 12.2 30.2 3.1 15.6 3.5 0.0 7.8 12.5 2.0 12.6 11.8 31.1 0.7 1.3 17.5 31.3 12.2 ARSD ENSG00000006756 "Arylsulfatase D" P51689 X 2903972-2929349 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 109.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 23.2;EFO-21: 24.5" "HPA004694, HPA063835" Approved Approved "Vesicles,Lipid droplets" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Lipid droplets" "HPA004694: AB_1078221, HPA063835: AB_2685132" "unprognostic (3.92e-1)" "unprognostic (7.50e-2)" "unprognostic (3.33e-1)" "prognostic favorable (5.21e-4)" "unprognostic (5.90e-3)" "unprognostic (6.32e-3)" "unprognostic (1.73e-1)" "unprognostic (1.34e-1)" "unprognostic (2.44e-1)" "unprognostic (4.09e-3)" "unprognostic (7.18e-2)" "unprognostic (3.93e-1)" "prognostic favorable (1.97e-5)" "unprognostic (1.37e-1)" "unprognostic (3.93e-2)" "unprognostic (4.99e-2)" "unprognostic (2.11e-3)" 8.4 7.8 4.3 6.1 4.1 4.9 23.6 4.2 4.5 23.9 10.7 20.5 21.0 11.2 15.9 10.0 28.0 11.4 4.8 4.1 5.1 38.9 40.0 16.8 3.6 6.3 5.7 18.7 32.4 12.7 4.2 8.6 5.4 19.3 14.8 1.7 17.5 13.3 1.7 7.3 15.4 7.6 5.6 7.2 30.4 3.8 4.6 2.8 21.1 3.2 4.2 11.7 8.4 5.0 6.9 12.0 3.2 15.4 13.6 7.7 0.1 3.9 7.1 1.7 1.1 0.7 23.2 0.0 24.5 7.9 18.1 0.0 0.6 2.0 1.6 0.2 0.0 0.0 0.0 4.0 7.5 0.0 9.1 12.3 6.3 3.4 3.6 11.1 11.5 0.0 0.0 0.1 7.6 16.9 0.1 1.7 2.7 21.3 5.0 2.9 0.0 0.2 12.3 0.1 0.0 8.5 5.4 6.3 4.1 8.5 17.1 13.1 10.6 0.0 0.5 1.2 1.8 0.1 0.0 0.0 11.1 8.2 8.8 1.5 5.8 4.1 1.7 5.0 0.6 1.3 0.8 1.4 4.4 0.8 0.2 0.9 1.0 2.0 2.0 3.0 0.3 2.5 4.3 4.1 4.2 4.5 4.1 5.1 6.3 5.7 5.4 5.6 4.6 5.0 13.4 19.2 36.4 9.8 4.5 5.0 13.9 11.3 10.8 4.9 45.0 30.9 5.6 74.4 23.1 44.1 0.0 19.1 8.6 44.3 19.6 35.1 0.7 68.6 19.6 13.8 67.9 3.4 0.9 53.9 25.0 7.9 31.6 67.8 16.5 66.8 11.7 109.9 18.5 0.0 1.7 56.2 10.2 17.8 6.4 1.4 6.2 16.1 14.2 6.5 23.1 5.8 11.3 3.5 1.5 47.4 47.9 6.8 1.6 18.1 53.1 23.4 25.8 0.9 6.6 15.1 10.7 1.3 3.9 16.2 7.2 26.0 4.3 38.3 60.9 16.4 ARSK "DKFZp313G1735, TSULF" ENSG00000164291 "Arylsulfatase family member K" Q6UWY0 5 95555101-95605102 "Plasma proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 19.1" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 47.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042384 Approved Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles Nucleoplasm "HPA042384: AB_10795703" "unprognostic (9.50e-2)" "unprognostic (1.37e-1)" "unprognostic (2.03e-3)" "unprognostic (2.39e-1)" "unprognostic (3.33e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (2.59e-4)" "unprognostic (3.39e-1)" "unprognostic (1.37e-1)" "unprognostic (5.19e-2)" "unprognostic (7.61e-2)" "unprognostic (2.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.91e-2)" "unprognostic (2.32e-1)" "unprognostic (8.20e-2)" "unprognostic (1.06e-2)" 3.0 3.7 2.1 2.2 2.3 2.3 3.3 2.8 3.0 3.8 2.1 2.7 2.2 3.6 4.2 2.9 3.2 3.1 2.6 2.4 2.1 5.4 3.7 2.9 2.7 1.9 1.9 5.8 4.9 19.1 2.6 5.5 2.3 4.9 2.5 3.6 2.8 4.9 2.3 3.3 2.2 3.0 1.7 2.4 4.2 1.6 2.6 3.7 5.0 2.7 2.0 3.2 3.3 2.2 5.1 3.2 6.6 6.6 32.4 16.8 9.5 15.9 9.2 6.1 12.4 3.9 7.8 6.9 8.1 5.5 10.9 4.6 5.8 10.1 13.3 7.4 8.5 5.5 7.7 6.7 9.4 3.1 4.4 12.4 8.9 9.2 5.9 12.8 10.0 9.3 5.6 7.4 13.7 2.5 8.5 5.9 8.6 1.6 15.3 5.2 10.6 11.0 14.1 1.2 4.7 4.8 9.7 3.1 10.0 9.1 8.9 3.2 18.1 9.6 7.8 15.0 9.9 6.2 11.2 8.4 9.6 8.0 36.5 12.9 1.1 2.1 4.0 1.2 4.7 4.9 4.7 5.4 0.6 5.0 7.0 5.2 0.9 3.3 0.7 2.2 3.9 1.8 2.1 2.3 2.8 3.0 2.4 2.1 1.9 1.9 2.3 1.7 2.6 2.2 6.8 3.2 2.2 9.1 6.6 4.5 6.8 7.4 5.7 7.3 4.4 7.2 4.6 1.5 3.7 7.3 12.5 11.8 6.6 1.9 3.9 4.1 9.2 7.1 10.3 6.2 3.0 10.1 11.0 2.5 47.4 13.6 2.0 5.7 22.9 8.1 6.8 16.5 4.6 10.1 9.7 2.0 10.2 3.2 5.4 2.9 10.8 4.9 5.4 7.5 5.1 12.7 14.4 7.1 10.0 2.6 3.2 11.7 7.1 3.9 3.2 4.8 6.8 10.4 0.0 10.2 10.9 7.4 8.6 5.1 7.0 5.1 9.8 11.8 3.4 2.1 ARV1 ENSG00000173409 "ARV1 homolog, fatty acid homeostasis modulator" Q9H2C2 1 230978981-231000733 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 116.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035709 Approved Uncertain Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA035709: AB_2674744" "unprognostic (2.32e-1)" "unprognostic (4.69e-2)" "prognostic favorable (1.33e-4)" "unprognostic (3.29e-1)" "unprognostic (1.42e-1)" "unprognostic (9.95e-2)" "unprognostic (5.66e-2)" "prognostic favorable (3.27e-5)" "unprognostic (1.37e-1)" "unprognostic (1.12e-2)" "unprognostic (9.57e-2)" "unprognostic (9.82e-2)" "unprognostic (2.31e-1)" "unprognostic (4.82e-1)" "unprognostic (5.63e-2)" "unprognostic (1.39e-1)" "unprognostic (8.12e-3)" 10.6 18.4 23.4 10.2 24.5 13.9 19.0 26.2 32.8 12.2 25.7 24.6 16.4 9.7 22.9 15.7 14.3 16.4 30.1 24.5 25.6 25.2 26.2 15.0 14.8 25.2 24.1 11.2 17.5 33.3 20.1 11.7 25.0 16.2 25.9 29.0 22.0 15.2 21.7 17.8 17.3 13.1 25.7 13.5 17.1 31.3 25.2 15.0 21.9 24.8 15.3 15.2 11.2 27.7 40.8 43.6 20.8 25.1 29.6 26.4 20.1 19.0 34.0 33.5 38.3 16.3 31.4 11.4 22.7 21.3 20.5 32.3 40.6 25.5 39.2 30.4 55.7 36.8 28.9 22.1 30.5 53.6 27.9 28.0 25.8 18.1 20.9 21.9 22.5 34.7 53.7 30.7 22.2 14.3 22.3 16.4 27.1 43.0 27.1 25.2 32.1 33.1 47.1 33.0 21.2 32.6 22.6 26.6 57.9 5.3 46.6 46.6 13.9 13.4 8.7 23.6 45.9 47.4 44.6 28.9 36.8 45.9 36.7 9.1 8.1 8.5 10.0 12.2 13.9 18.1 11.2 12.4 10.1 11.2 13.7 13.0 2.0 12.7 21.2 14.9 15.4 9.0 23.4 24.5 26.2 32.8 24.5 25.6 25.2 24.1 25.0 25.7 25.2 27.7 13.6 16.0 31.7 10.7 12.6 12.9 22.0 75.8 11.4 18.9 14.8 15.6 32.2 21.5 38.9 29.5 2.1 37.9 12.7 15.8 60.7 24.1 52.6 12.7 10.9 12.7 7.7 58.1 20.2 40.8 14.5 14.5 11.7 9.7 17.1 14.4 15.0 17.3 24.9 38.7 25.6 18.5 34.6 13.3 5.5 22.9 9.3 13.5 24.9 8.4 9.8 33.6 7.2 8.5 19.3 21.5 11.5 16.6 14.7 11.6 17.9 32.5 27.3 20.0 0.0 11.4 15.6 116.7 21.0 20.3 15.2 15.6 11.4 22.0 26.4 20.9 ASAP3 "CENTB6, DDEFL1, FLJ20199, UPLC1" ENSG00000088280 "ArfGAP with SH3 domain, ankyrin repeat and PH domain 3" Q8TDY4 1 23428563-23484568 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 35.9;Extravillous trophoblasts: 43.3;Granulosa cells: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 31.8;ASC TERT1: 29.9;HSkMC: 38.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020537, HPA020546" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 50: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Vesicles Nucleoplasm "HPA020537: AB_2670467, HPA020546: AB_2670470" "unprognostic (2.51e-1)" "unprognostic (2.70e-2)" "unprognostic (4.35e-3)" "prognostic unfavorable (5.56e-4)" "unprognostic (3.87e-1)" "unprognostic (2.24e-2)" "unprognostic (1.19e-3)" "prognostic favorable (2.80e-4)" "unprognostic (1.88e-2)" "prognostic unfavorable (8.30e-4)" "unprognostic (2.24e-1)" "unprognostic (1.18e-1)" "prognostic favorable (5.12e-5)" "unprognostic (3.39e-3)" "unprognostic (3.92e-2)" "unprognostic (2.02e-2)" "unprognostic (7.27e-2)" 24.1 39.1 11.5 3.2 11.6 0.1 21.9 12.5 12.4 32.6 10.0 18.4 1.6 18.6 4.2 32.3 24.3 5.1 30.1 10.5 11.2 21.4 19.8 15.9 1.6 14.5 12.7 58.3 22.2 11.7 18.6 8.0 13.2 31.0 5.2 3.0 38.0 8.0 42.9 52.9 11.0 5.9 12.7 5.0 25.4 18.2 13.4 1.0 29.0 11.7 4.2 21.3 33.4 12.1 1.8 1.8 17.6 11.6 31.8 29.9 21.6 3.2 3.8 4.9 6.3 1.3 0.1 9.2 3.7 6.3 2.9 8.4 12.2 2.9 2.8 0.4 1.6 0.5 4.8 11.8 17.1 0.0 0.9 38.4 4.4 7.9 7.1 14.6 3.9 1.3 6.4 0.0 3.1 3.9 1.3 0.1 3.0 5.0 4.2 4.9 1.9 0.0 3.4 3.7 0.6 6.0 14.1 3.5 3.5 8.7 13.2 0.1 1.4 2.1 5.2 5.9 0.2 3.9 4.2 1.1 0.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 11.5 11.6 12.5 12.4 10.5 11.2 14.5 12.7 13.2 12.7 13.4 12.1 4.5 9.6 6.7 35.9 0.3 2.0 1.5 2.0 2.8 1.1 6.3 3.7 15.5 0.0 4.1 3.7 0.0 2.1 0.0 6.7 3.9 5.8 5.1 2.4 7.3 6.6 1.2 0.0 7.6 6.1 43.3 12.2 10.2 4.4 1.3 28.3 3.9 4.0 1.8 0.0 4.9 8.5 2.0 0.0 1.3 8.1 12.5 0.4 0.0 7.5 0.1 8.3 0.0 18.1 4.2 2.5 2.1 13.5 0.2 2.4 0.8 5.4 4.3 0.6 0.0 2.0 3.4 8.2 11.8 3.7 4.3 1.4 0.2 15.9 5.2 2.1 ASB7 ENSG00000183475 "Ankyrin repeat and SOCS box containing 7" Q9H672 15 100602589-100651701 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003300 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 59: Non-specific - Transcription" "Golgi apparatus, Vesicles" Nucleoplasm "HPA003300: AB_1845071" "unprognostic (1.38e-1)" "unprognostic (3.48e-2)" "unprognostic (3.91e-2)" "unprognostic (4.65e-2)" "unprognostic (1.37e-1)" "unprognostic (1.82e-1)" "unprognostic (1.20e-1)" "unprognostic (5.55e-2)" "unprognostic (1.34e-1)" "unprognostic (1.55e-2)" "unprognostic (1.51e-2)" "unprognostic (3.14e-2)" "unprognostic (2.18e-2)" "unprognostic (3.09e-2)" "unprognostic (1.10e-1)" "unprognostic (2.17e-1)" "unprognostic (1.46e-2)" 4.6 3.6 4.2 4.5 4.7 12.8 5.1 4.9 4.6 5.2 5.6 6.8 4.6 5.3 6.5 4.6 5.7 3.8 3.9 4.2 4.1 6.7 6.8 4.9 6.3 4.5 4.3 5.7 3.5 6.7 3.1 4.3 4.2 4.7 6.3 4.9 4.5 4.3 3.1 4.4 4.4 6.0 4.2 5.9 4.3 6.8 4.9 7.0 6.2 4.7 6.3 5.1 3.5 5.0 6.7 14.5 6.6 7.9 8.6 9.2 7.5 7.2 13.0 11.8 12.3 8.8 13.2 10.9 6.4 9.2 11.6 14.5 9.2 9.4 12.2 7.6 9.8 14.4 9.0 8.8 13.0 8.6 12.3 8.9 10.3 9.6 15.8 11.4 11.0 11.7 8.6 8.9 6.8 7.2 6.7 8.7 6.3 14.9 6.9 9.0 14.1 9.2 11.8 14.8 6.5 9.2 11.1 10.8 15.0 12.5 7.6 10.7 8.4 10.3 9.5 7.3 10.2 10.6 23.5 10.4 8.0 7.8 8.3 1.2 5.8 10.2 5.2 4.7 4.2 4.3 4.5 6.4 5.1 4.2 6.2 4.4 5.2 4.3 3.1 3.3 5.7 4.8 4.2 4.7 4.9 4.6 4.2 4.1 4.5 4.3 4.2 4.2 4.9 5.0 4.6 0.0 5.4 14.7 6.6 6.5 2.3 3.5 13.1 4.9 6.2 4.1 3.4 12.8 6.4 3.7 6.2 3.8 9.9 12.9 1.9 5.7 4.0 8.1 8.3 6.7 8.4 3.0 20.6 4.9 3.0 4.0 7.1 8.1 10.8 7.3 4.2 8.0 6.0 13.5 15.0 6.2 4.1 7.8 4.3 2.1 5.0 5.2 3.6 20.6 7.8 3.1 6.2 16.6 17.4 6.5 9.7 5.3 4.9 5.5 5.4 7.1 10.3 5.0 0.0 4.3 4.3 9.9 8.2 10.8 4.5 5.9 8.2 6.7 5.8 5.6 ASGR1 CLEC4H1 ENSG00000141505 "Asialoglycoprotein receptor 1" P07306 17 7173431-7179564 "Predicted intracellular proteins, Predicted secreted proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 41 "liver: 1092.3" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 1107.9" "Cancer enriched" "Detected in many" 90 "liver cancer: 131.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 115.2;intermediate monocyte: 55.5;myeloid DC: 41.2" "Group enriched" "Detected in many" 8 "dendritic cells: 41.2;monocytes: 115.2" "Cell line enriched" "Detected in some" 29 "Hep G2: 493.2" "Region enriched" "Detected in all" 9 "cerebellum: 44.1" "Not detected" "Not detected" "HPA011954, HPA012852" Enhanced Supported "Vesicles,Cell Junctions" "Secreted to blood" NA NA 10000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Cell Junctions" "HPA011954: AB_1845079, HPA012852: AB_1845080" "unprognostic (3.56e-3)" "unprognostic (3.57e-1)" "unprognostic (8.76e-2)" "unprognostic (4.05e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (1.86e-2)" "unprognostic (5.37e-2)" "unprognostic (2.15e-1)" "unprognostic (2.39e-1)" "unprognostic (8.55e-5)" "unprognostic (1.55e-1)" "unprognostic (8.33e-11)" "unprognostic (1.45e-1)" "unprognostic (2.00e-1)" "unprognostic (1.73e-3)" "unprognostic (4.46e-3)" 2.6 1.5 7.7 3.7 7.8 2.5 1.8 17.0 10.9 1.6 7.0 1.2 2.2 1.3 0.6 1.7 1.8 2.9 1.1 7.9 7.6 1.4 1092.3 3.9 1.3 8.0 8.2 1.1 0.9 7.0 2.9 0.5 8.3 1.7 0.5 4.8 0.9 0.3 1.5 4.4 1.4 1.3 6.0 4.8 1.4 26.5 7.8 0.4 5.8 0.4 0.3 1.7 1.5 8.7 0.3 0.7 9.2 4.2 0.0 0.2 0.8 0.8 0.9 0.9 1.6 16.8 0.5 0.3 1.1 0.2 0.4 0.2 0.3 0.2 0.4 0.3 0.8 1.2 1.4 493.2 0.1 0.8 1.7 1.2 0.2 0.5 0.1 0.6 8.4 7.4 1.1 0.6 0.5 0.4 0.7 1.2 1.7 0.2 0.4 0.9 3.5 0.2 0.1 0.7 0.6 3.5 0.7 0.3 0.6 1.5 0.5 0.2 1.2 0.9 3.4 0.7 0.4 0.2 0.3 0.5 0.6 0.4 0.3 10.0 115.2 0.4 0.2 55.5 1.1 0.5 0.2 0.2 41.2 0.5 0.3 0.4 3.3 0.5 14.9 1.8 0.3 36.7 7.7 7.8 17.0 10.9 7.9 7.6 8.0 8.2 8.3 6.0 7.8 8.7 6.0 0.0 4.7 2.9 2.6 3.2 1.7 2.0 3.4 37.8 5.6 6.0 1.5 55.8 2.0 3.7 160.6 3.6 2.9 1.4 3.9 0.9 235.4 4.2 3.6 13.2 15.6 16.8 4.6 0.2 3.7 1.9 3.6 16.5 0.0 5.1 27.5 1107.9 39.9 15.2 4.8 2.3 2.0 97.4 11.9 115.8 2.5 52.6 0.0 1.9 77.2 3.6 0.0 2.0 0.6 0.3 1.3 1.2 0.0 0.9 0.2 6.8 1.6 42.3 0.0 0.8 1.9 6.5 9.7 9.9 4.8 12.4 1.4 1.6 1.3 2.4 ASIP "AGTIL, ASP" ENSG00000101440 "Agouti signaling protein" P42127 20 34194569-34269344 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "epididymis: 14.8;heart muscle: 28.0;ovary: 41.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 27.4;dendritic cells: 44.1;Hofbauer cells: 15.1;Leydig cells: 12.5;Peritubular cells: 10.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 356 "plasmacytoid DC: 134.8" "Lineage enriched" "Detected in single" 356 "dendritic cells: 134.8" "Cell line enhanced" "Detected in some" "CACO-2: 3.2;HSkMC: 2.4;SK-MEL-30: 1.9;U-698: 1.9" "Not detected" "Not detected" HPA048636 Uncertain Supported Vesicles "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA048636: AB_2680471" "unprognostic (4.81e-2)" "unprognostic (7.46e-2)" "unprognostic (1.97e-3)" "unprognostic (3.26e-2)" "unprognostic (2.24e-1)" "unprognostic (3.07e-2)" "unprognostic (5.13e-2)" "unprognostic (4.57e-2)" "unprognostic (4.52e-2)" "unprognostic (1.61e-1)" "unprognostic (1.62e-1)" "unprognostic (1.48e-1)" "unprognostic (5.53e-6)" "unprognostic (1.02e-1)" "unprognostic (3.09e-1)" "unprognostic (1.27e-1)" "unprognostic (1.33e-1)" 1.4 0.6 0.2 0.0 0.5 0.3 2.4 0.1 0.4 4.2 0.0 0.5 0.0 2.0 14.8 0.1 4.0 0.1 28.0 0.1 0.1 0.9 1.3 0.3 0.4 0.2 0.1 41.7 0.1 0.0 0.6 0.2 0.6 1.5 0.0 0.3 0.7 0.2 0.9 5.7 0.8 0.0 0.0 0.3 0.3 1.5 0.2 0.2 0.3 1.2 0.5 0.5 1.1 0.3 0.0 1.1 0.4 0.4 0.2 0.7 0.1 0.1 0.0 0.0 0.0 3.2 0.0 1.2 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.7 1.7 0.3 0.5 0.0 0.0 0.4 2.4 0.0 0.0 0.0 0.1 0.0 0.7 0.6 0.9 0.0 0.3 0.2 1.7 0.0 0.1 0.6 0.3 0.3 1.4 0.0 0.1 0.2 0.2 0.0 0.2 1.9 0.5 0.3 0.2 0.3 0.5 0.5 0.0 0.3 0.4 0.4 1.9 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.0 134.8 0.0 0.6 0.2 0.5 0.1 0.4 0.1 0.1 0.2 0.1 0.6 0.0 0.2 0.3 0.4 0.0 0.6 1.3 0.8 2.5 0.0 0.0 0.0 0.0 0.3 0.5 27.4 0.0 0.0 0.0 0.0 0.2 44.1 0.0 1.9 0.0 1.1 0.3 9.2 1.2 0.0 0.0 2.1 0.0 0.2 5.6 0.0 0.4 0.0 0.2 2.5 5.8 15.1 0.0 1.8 0.0 0.0 0.8 7.0 1.7 12.5 2.1 1.8 1.0 0.3 0.0 0.0 2.5 2.5 0.1 0.0 10.5 0.0 0.1 0.0 8.3 0.0 0.0 6.6 0.1 0.6 1.7 1.9 0.2 3.1 0.8 0.6 1.0 0.0 0.1 ASPSCR1 "ASPL, ASPS, TUG, UBXD9, UBXN9" ENSG00000169696 "ASPSCR1 tether for SLC2A4, UBX domain containing" Q9BZE9 17 81976807-82017406 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 222.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "Hep G2: 298.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026749 Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Vesicles, Plasma membrane" "HPA026749: AB_1845114" "unprognostic (5.01e-2)" "unprognostic (1.19e-3)" "unprognostic (7.61e-2)" "unprognostic (1.34e-1)" "unprognostic (1.36e-1)" "prognostic favorable (8.55e-4)" "unprognostic (2.02e-1)" "unprognostic (2.07e-2)" "unprognostic (3.43e-1)" "unprognostic (1.71e-3)" "prognostic favorable (2.67e-4)" "unprognostic (1.13e-1)" "prognostic unfavorable (1.26e-4)" "unprognostic (3.16e-2)" "unprognostic (1.13e-1)" "unprognostic (2.27e-1)" "unprognostic (1.01e-2)" 16.5 20.4 16.6 8.4 17.0 15.0 16.9 16.5 20.4 16.2 17.7 16.0 13.6 15.6 7.9 16.8 14.0 7.7 26.1 16.2 15.5 27.3 57.9 17.3 12.2 20.1 16.6 13.4 22.8 14.8 30.6 12.9 18.3 21.6 4.6 5.7 18.3 6.7 44.3 20.5 18.1 5.2 14.7 20.7 22.7 30.0 17.2 8.3 25.9 5.8 6.4 16.0 14.2 21.5 19.3 33.3 13.0 17.9 7.5 9.3 55.4 17.7 12.6 19.3 19.5 20.3 21.3 19.2 18.1 12.4 16.3 9.8 12.0 13.1 6.2 12.9 41.0 21.4 28.7 298.1 25.5 19.1 29.9 10.9 13.9 9.5 6.6 10.0 19.5 16.0 22.0 25.0 11.6 65.0 16.9 41.8 15.5 32.8 23.5 19.2 18.7 39.4 18.0 17.0 32.4 34.8 14.6 42.2 35.2 12.3 27.2 41.4 16.6 35.7 24.5 26.4 22.8 20.2 12.5 21.6 19.2 19.3 21.3 24.0 11.7 8.6 6.6 8.0 3.7 9.0 10.0 8.8 14.7 9.0 7.7 5.8 2.7 8.0 10.4 9.3 5.3 5.6 16.6 17.0 16.5 20.4 16.2 15.5 20.1 16.6 18.3 14.7 17.2 21.5 13.9 9.6 44.7 19.9 24.1 13.4 23.7 24.4 23.3 23.3 19.6 15.6 13.6 27.1 19.8 14.7 41.7 73.7 25.8 29.3 39.2 24.2 49.1 16.2 14.9 16.1 25.0 17.9 12.4 26.2 222.6 17.5 46.9 20.1 21.5 31.0 12.8 56.1 44.7 50.5 12.1 31.5 20.3 26.7 18.6 96.0 11.8 21.7 19.6 1.9 23.8 57.8 19.6 10.6 14.1 17.6 25.8 17.7 27.3 24.9 42.5 58.3 18.5 39.4 13.1 14.7 37.4 41.7 51.0 20.3 14.3 59.4 18.4 23.6 33.3 23.1 ASTN1 ASTN ENSG00000152092 "Astrotactin 1" O14525 1 176857302-177164973 "Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 14.9;brain: 29.8;retina: 14.0" "Group enriched" "Detected in some" 6 "Astrocytes: 191.3;Excitatory neurons: 218.7;Inhibitory neurons: 275.6;Oligodendrocyte precursor cells: 280.0" "Cancer enriched" "Detected in some" 14 "glioma: 15.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 5.8;NTERA-2: 4.4;SCLC-21H: 2.7;U-2 OS: 3.4;U-266/84: 21.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074112 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 65: Brain - Ion transport" "Cluster 16: U-266 - Nucleosome" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus, Vesicles" "HPA074112: AB_2686662" "unprognostic (4.41e-3)" "unprognostic (1.48e-2)" "unprognostic (4.03e-1)" "unprognostic (1.31e-1)" "unprognostic (2.55e-1)" "unprognostic (7.61e-2)" "unprognostic (2.03e-4)" "unprognostic (3.86e-3)" "unprognostic (1.08e-1)" "unprognostic (4.36e-1)" "unprognostic (1.67e-3)" "unprognostic (1.98e-1)" "unprognostic (6.77e-2)" "unprognostic (4.74e-3)" "unprognostic (2.88e-1)" "unprognostic (5.47e-2)" "unprognostic (1.16e-1)" 0.8 14.9 22.9 0.4 27.1 0.0 0.7 3.0 29.8 0.4 0.0 0.5 0.3 0.9 3.3 0.0 1.6 0.6 0.5 28.5 23.3 0.1 0.2 0.2 0.1 6.1 10.7 5.7 0.5 0.1 9.0 0.3 7.5 1.0 0.3 14.0 0.9 1.6 0.1 0.1 0.3 0.9 11.5 2.2 0.3 0.7 22.7 0.0 0.0 0.3 0.3 0.0 0.4 11.5 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.8 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 21.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.9 27.1 3.0 29.8 28.5 23.3 6.1 10.7 7.5 11.5 22.7 11.5 0.0 0.0 0.0 191.3 0.0 0.1 0.0 0.0 0.0 7.9 0.2 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.8 0.3 0.2 0.0 0.0 218.7 0.0 0.1 0.7 0.0 0.2 0.0 4.0 5.0 0.0 0.5 23.5 275.6 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 25.3 0.0 0.8 0.0 280.0 35.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.7 4.4 1.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 ATG12 "APG12, APG12L" ENSG00000145782 "Autophagy related 12" O94817 5 115828200-115841837 "Predicted intracellular proteins, Transporters" "Autophagy, Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013272, HPA068989" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" "CAB013272: AB_2533272, HPA068989: " "unprognostic (2.48e-2)" "unprognostic (1.40e-1)" "unprognostic (2.38e-1)" "unprognostic (1.29e-1)" "unprognostic (1.22e-1)" "unprognostic (2.25e-2)" "prognostic unfavorable (1.36e-4)" "unprognostic (2.72e-2)" "unprognostic (2.87e-2)" "unprognostic (5.51e-2)" "unprognostic (9.36e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.54e-7)" "unprognostic (1.27e-1)" "unprognostic (1.93e-1)" "prognostic unfavorable (4.99e-4)" "unprognostic (5.11e-2)" 15.5 10.5 12.3 10.7 12.7 11.3 10.2 12.9 16.9 12.0 10.5 10.4 11.6 10.8 11.9 11.3 9.8 11.6 9.7 12.6 13.3 7.1 18.4 10.4 13.6 13.2 13.2 12.0 9.5 7.4 8.7 13.6 13.7 10.8 11.1 9.6 7.9 10.9 11.1 9.0 11.9 12.7 12.7 11.2 8.8 9.4 12.8 14.0 8.6 12.6 11.6 11.8 8.8 15.0 20.7 10.9 26.3 24.1 42.9 57.4 20.0 34.9 38.3 22.6 36.5 15.8 16.5 17.8 14.5 32.1 35.3 11.3 20.5 29.4 36.4 93.2 20.2 11.5 13.0 14.8 33.7 12.8 22.0 43.0 31.5 25.1 29.6 26.3 27.6 19.0 16.8 24.4 43.5 13.5 27.2 20.2 17.9 15.7 23.6 19.8 25.4 25.7 15.7 13.7 25.8 27.6 37.3 14.7 36.6 20.0 20.3 19.2 28.3 41.3 18.9 38.2 36.0 18.7 31.5 28.9 37.7 27.2 39.6 15.4 11.5 19.3 11.8 13.6 16.5 12.3 14.3 11.7 10.3 12.2 14.6 14.1 20.9 14.4 17.4 13.8 12.3 11.0 12.3 12.7 12.9 16.9 12.6 13.3 13.2 13.2 13.7 12.7 12.8 15.0 52.5 44.8 41.0 17.0 82.8 85.8 65.4 81.6 44.3 42.3 46.8 36.1 45.2 38.6 56.9 25.8 77.2 61.8 92.3 50.3 37.2 60.6 28.7 49.0 60.7 55.1 41.8 23.8 28.5 81.6 134.1 75.2 36.2 55.8 96.9 48.8 47.5 57.9 68.2 30.3 26.5 54.5 59.0 72.1 69.8 14.9 64.0 53.7 53.4 19.7 76.8 34.1 99.9 26.7 35.5 105.5 45.8 53.8 50.1 68.4 56.3 44.3 49.7 59.2 26.3 39.5 50.5 50.0 45.1 40.0 84.7 88.7 78.8 45.1 46.0 78.1 ATG2A KIAA0404 ENSG00000110046 "Autophagy related 2A" Q2TAZ0 11 64894546-64917211 "Predicted intracellular proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 16.9" "Lineage enriched" "Detected in many" 7 "granulocytes: 16.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038715 Uncertain Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Vesicles Nucleoplasm "HPA038715: AB_10673474" "unprognostic (3.05e-2)" "unprognostic (2.33e-1)" "unprognostic (7.55e-2)" "unprognostic (1.18e-1)" "unprognostic (3.42e-1)" "unprognostic (9.23e-3)" "unprognostic (1.88e-2)" "unprognostic (1.12e-1)" "unprognostic (1.37e-1)" "unprognostic (2.68e-2)" "unprognostic (1.05e-1)" "unprognostic (1.66e-2)" "prognostic favorable (4.79e-5)" "unprognostic (2.92e-2)" "unprognostic (2.69e-1)" "unprognostic (3.37e-1)" "unprognostic (1.15e-1)" 16.4 20.1 11.4 6.5 10.9 60.2 16.9 8.6 40.1 19.9 11.4 18.9 7.5 18.2 1.8 15.7 19.2 4.2 18.4 11.5 9.8 22.0 59.2 24.2 6.1 13.9 12.3 24.9 22.7 4.9 21.6 4.9 12.7 21.6 2.6 1.9 15.2 5.7 26.7 34.9 21.4 3.3 9.0 25.7 23.2 15.3 11.4 5.4 19.3 4.4 3.3 17.7 15.6 10.4 13.2 12.6 4.4 12.0 5.7 4.0 12.3 7.1 10.3 9.4 6.8 11.0 9.9 9.3 14.7 6.0 12.0 10.8 4.5 8.3 2.5 9.1 15.7 8.7 19.1 10.0 8.4 6.5 18.2 10.9 7.1 11.8 6.3 5.4 7.9 9.5 16.1 7.3 4.1 21.3 7.8 21.9 5.1 3.5 14.3 8.6 7.1 13.5 5.0 10.9 16.5 6.7 10.6 14.6 13.3 3.3 14.3 8.1 10.1 9.0 8.6 18.3 5.3 14.7 5.5 6.5 13.0 5.2 5.6 3.0 2.0 2.2 2.5 2.1 2.1 0.8 1.7 2.2 1.4 0.9 1.3 2.4 16.9 1.8 1.7 2.4 0.9 1.2 11.4 10.9 8.6 40.1 11.5 9.8 13.9 12.3 12.7 9.0 11.4 10.4 9.8 9.6 16.2 20.2 17.0 28.9 8.7 35.7 16.5 16.6 15.8 10.3 8.1 7.2 17.6 9.2 33.3 12.7 40.1 38.8 1.9 10.2 2.5 12.4 9.2 10.2 35.9 16.2 7.6 10.3 5.3 12.6 16.8 24.4 9.5 15.4 7.9 23.2 10.9 13.5 8.4 17.6 24.4 20.1 19.9 3.6 12.8 24.2 30.2 5.6 11.9 12.3 19.6 6.6 7.1 14.9 21.7 10.1 27.3 12.2 26.8 6.6 13.3 26.0 13.1 11.6 10.6 9.0 6.2 16.3 38.4 66.9 40.2 27.2 19.0 15.9 ATG9A "APG9L1, FLJ22169" ENSG00000198925 "Autophagy related 9A" Q7Z3C6 2 219219380-219229717 "Predicted membrane proteins, Transporters" "Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 83.8;Late spermatids: 105.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059551 Uncertain Supported Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "HPA059551: AB_2684060" "unprognostic (1.53e-2)" "unprognostic (4.03e-1)" "unprognostic (1.46e-2)" "unprognostic (5.04e-2)" "unprognostic (4.80e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (2.18e-5)" "unprognostic (8.99e-3)" "unprognostic (2.07e-1)" "unprognostic (3.55e-3)" "unprognostic (4.67e-2)" "unprognostic (4.21e-1)" "unprognostic (2.23e-2)" "unprognostic (4.84e-2)" "unprognostic (3.15e-1)" "unprognostic (5.61e-2)" "unprognostic (1.95e-2)" 25.6 23.6 27.2 17.3 29.0 44.7 19.2 27.8 36.6 19.5 10.0 25.6 31.4 24.1 14.2 31.4 18.8 21.8 42.1 30.0 24.3 20.0 25.9 23.7 19.4 29.0 26.7 20.4 28.1 31.2 17.6 30.7 26.2 21.6 21.8 24.6 23.9 22.8 116.8 32.1 29.7 28.1 24.3 21.7 22.8 62.2 27.6 15.7 18.4 62.7 21.2 22.7 22.7 28.6 29.4 35.7 26.9 64.0 50.3 55.1 35.9 52.1 56.1 67.3 60.2 52.9 38.8 7.7 43.7 79.8 54.7 58.0 43.2 56.9 49.6 22.6 70.7 55.7 90.1 63.9 54.9 14.1 40.6 56.7 91.4 68.7 63.0 60.9 68.2 18.6 75.6 27.0 46.2 38.3 12.2 33.4 19.5 28.5 26.9 16.9 36.7 30.2 40.0 38.6 42.6 25.7 52.0 46.7 46.5 52.0 17.3 39.3 52.5 67.0 32.3 28.7 47.1 15.5 14.7 11.2 55.7 33.9 37.2 6.5 12.4 6.3 7.2 18.0 7.2 5.6 5.6 9.1 8.5 3.6 5.4 6.1 11.2 9.7 22.6 4.1 7.1 11.6 27.2 29.0 27.8 36.6 30.0 24.3 29.0 26.7 26.2 24.3 27.6 28.6 0.3 0.0 4.5 12.7 8.2 7.8 7.6 10.6 8.6 18.9 0.3 0.3 33.2 17.2 7.1 0.0 14.6 26.8 4.1 44.0 0.0 0.2 83.8 0.6 1.5 10.0 13.8 34.7 15.2 0.5 24.4 9.1 11.7 0.8 10.2 0.3 16.8 37.1 11.5 21.9 14.1 17.6 6.1 13.3 7.0 105.9 14.0 4.8 10.6 5.6 7.0 20.5 9.2 9.5 12.5 0.3 27.6 8.6 6.7 13.4 39.3 0.3 4.7 15.7 13.1 7.1 5.5 54.9 13.8 14.2 11.1 34.8 7.5 0.8 18.5 10.5 ATM "ATA, ATC, ATD, ATDC, TEL1, TELO1" ENSG00000149311 "ATM serine/threonine kinase" Q13315 11 108222832-108369102 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 210.6;NK-cells: 339.8;Oligodendrocytes: 217.6;Rod photoreceptor cells: 200.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 78.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000102, HPA067142" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm Vesicles "CAB000102: , HPA067142: AB_2685789" "unprognostic (9.77e-2)" "unprognostic (1.47e-1)" "unprognostic (3.04e-1)" "unprognostic (2.36e-1)" "unprognostic (5.70e-2)" "unprognostic (2.86e-2)" "unprognostic (6.32e-3)" "unprognostic (1.05e-1)" "unprognostic (8.19e-2)" "unprognostic (1.63e-1)" "unprognostic (7.68e-2)" "unprognostic (6.16e-2)" "unprognostic (2.17e-3)" "unprognostic (3.10e-1)" "unprognostic (7.87e-2)" "unprognostic (1.21e-1)" "unprognostic (2.81e-1)" 6.2 7.4 8.2 17.5 15.0 16.2 8.5 17.0 12.3 8.7 16.1 6.7 5.2 10.0 9.9 4.0 7.5 8.2 7.0 7.3 11.3 5.8 7.8 7.6 33.7 15.8 13.1 15.8 14.8 9.3 12.1 8.0 17.0 6.3 7.0 20.6 11.4 6.1 4.4 7.5 12.6 6.9 10.3 22.2 8.6 5.2 12.7 18.2 8.8 6.0 25.9 7.1 6.9 28.8 4.3 6.8 14.8 7.6 20.2 29.1 3.1 10.9 13.5 6.4 11.3 7.1 10.3 18.3 14.0 10.2 9.6 7.7 11.6 10.8 9.0 12.3 5.7 15.2 8.7 10.2 10.5 16.4 17.0 18.3 6.3 10.0 21.2 15.2 14.1 16.5 12.4 9.9 14.3 3.4 10.6 18.5 9.8 8.6 7.4 9.7 9.7 24.9 8.1 7.5 9.0 10.5 11.1 4.7 20.6 13.2 9.3 10.1 23.7 15.8 8.4 7.3 9.0 6.2 7.0 78.3 7.0 19.0 18.8 21.3 5.5 4.0 16.5 5.7 11.1 11.6 11.7 12.5 2.6 13.0 21.1 20.4 9.9 9.7 13.3 6.2 6.1 5.3 8.2 15.0 17.0 12.3 7.3 11.3 15.8 13.1 17.0 10.3 12.7 28.8 23.7 38.5 20.8 62.7 146.4 12.6 17.5 21.1 28.5 111.0 19.6 14.2 39.9 12.8 19.5 22.0 210.6 16.9 140.2 4.2 5.9 9.9 19.2 14.4 52.1 25.9 20.4 39.1 70.2 12.3 13.2 39.0 12.8 20.9 13.3 45.9 32.9 23.3 29.1 60.6 82.8 14.9 26.4 96.4 34.0 5.1 39.4 69.2 26.6 178.9 63.2 27.3 339.8 85.5 217.6 7.6 7.6 27.8 96.5 9.1 8.9 11.1 16.0 200.1 26.3 41.4 29.2 31.5 37.4 15.8 12.4 4.2 147.7 52.3 11.5 10.2 ATP11A "ATPIH, ATPIS, KIAA1021" ENSG00000068650 "ATPase phospholipid transporting 11A" P98196 13 112690329-112887168 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 218.0;Alveolar cells type 2: 215.0;Cone photoreceptor cells: 235.6;Glandular and luminal cells: 176.3;Oligodendrocytes: 138.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035583, HPA035584" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Vesicles "Golgi apparatus" "HPA035583: AB_10671106, HPA035584: AB_10672096" "unprognostic (1.67e-1)" "unprognostic (5.06e-3)" "unprognostic (1.58e-1)" "unprognostic (5.27e-2)" "unprognostic (6.58e-2)" "unprognostic (8.84e-2)" "unprognostic (5.87e-3)" "unprognostic (1.80e-2)" "unprognostic (6.97e-2)" "unprognostic (1.54e-3)" "unprognostic (3.93e-2)" "unprognostic (4.23e-1)" "prognostic favorable (7.44e-4)" "unprognostic (3.85e-2)" "unprognostic (3.69e-1)" "unprognostic (3.26e-2)" "unprognostic (7.40e-3)" 10.2 10.4 12.3 8.9 22.0 18.2 6.1 18.3 16.8 13.0 5.7 4.4 9.9 10.1 5.8 7.0 8.7 15.0 21.4 9.7 12.5 12.7 10.1 39.5 5.8 25.3 22.2 6.5 12.4 23.1 16.2 10.1 22.9 4.3 3.2 14.9 9.0 3.9 13.1 8.9 8.3 9.1 15.7 8.9 5.3 8.9 21.9 8.2 13.9 17.3 6.1 6.5 5.9 40.2 28.0 14.0 17.5 20.5 8.7 11.7 30.9 13.0 7.6 10.9 8.8 44.5 31.5 14.1 15.5 11.0 14.0 23.2 15.8 10.8 10.5 14.2 14.9 16.3 11.9 23.3 13.6 30.8 25.5 7.9 8.2 13.2 8.0 8.8 29.0 12.6 11.4 2.3 7.7 10.5 14.1 19.4 7.5 31.8 9.9 12.2 7.1 8.1 59.3 6.4 27.8 7.7 12.7 16.3 10.7 22.4 6.2 40.4 19.2 0.0 23.3 14.1 9.9 7.4 15.5 5.9 4.8 28.3 12.2 0.0 1.1 1.7 0.4 1.6 0.3 0.6 0.2 0.2 0.6 1.8 0.3 0.2 3.1 0.0 1.5 0.5 0.0 0.3 12.3 22.0 18.3 16.8 9.7 12.5 25.3 22.2 22.9 15.7 21.9 40.2 25.6 218.0 215.0 22.2 11.3 10.8 3.4 4.9 1.2 42.0 5.2 3.7 42.3 31.5 29.4 16.5 235.6 1.7 7.0 2.4 5.9 32.7 0.9 51.2 24.2 34.2 12.0 3.8 35.0 11.4 32.2 16.5 8.6 176.3 12.0 62.2 27.1 16.5 20.7 13.5 32.5 3.5 14.2 33.6 16.9 1.9 11.1 29.3 10.6 48.7 36.9 11.0 6.2 33.7 138.3 24.3 6.1 4.9 7.7 7.7 10.5 15.7 13.3 44.8 0.0 9.5 12.8 4.0 10.1 6.3 9.7 8.6 8.4 8.7 5.9 3.9 ATP13A1 "ATP13A, CGI-152, FLJ31858, KIAA1825" ENSG00000105726 "ATPase 13A1" Q9HD20 19 19645198-19663676 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031798, HPA049717" Approved Approved Vesicles NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA031798: AB_2674048, HPA049717: AB_2680858" "unprognostic (2.08e-1)" "unprognostic (4.92e-2)" "unprognostic (4.30e-2)" "unprognostic (7.29e-2)" "unprognostic (3.33e-1)" "unprognostic (4.40e-3)" "unprognostic (3.97e-3)" "unprognostic (1.73e-2)" "unprognostic (3.17e-1)" "unprognostic (2.60e-2)" "unprognostic (1.16e-2)" "unprognostic (9.43e-3)" "prognostic unfavorable (6.51e-4)" "unprognostic (2.26e-3)" "unprognostic (3.33e-2)" "unprognostic (1.14e-1)" "unprognostic (1.57e-1)" 12.9 17.0 7.3 21.8 6.5 16.1 13.9 5.4 8.6 17.1 12.3 15.6 18.6 16.2 8.0 15.6 15.0 14.0 9.7 7.4 7.9 12.8 12.9 14.0 21.4 7.9 6.5 20.8 21.1 23.4 18.1 12.9 6.9 15.1 13.0 8.8 17.7 12.6 12.8 16.2 22.2 11.6 6.1 26.4 16.7 15.8 7.6 15.9 20.2 5.8 17.5 13.9 14.4 9.0 32.8 45.2 24.3 52.8 38.2 25.3 66.1 28.9 40.1 24.5 24.9 43.5 54.3 44.9 48.6 34.4 14.0 17.8 37.2 37.0 13.4 16.5 77.6 24.6 48.7 34.5 39.3 46.8 70.1 36.7 34.2 26.5 31.8 27.1 17.9 32.1 43.0 97.5 24.7 53.9 31.8 33.7 44.5 40.6 54.7 25.0 17.4 100.9 25.8 44.7 33.4 56.7 26.8 42.6 30.0 11.4 26.9 50.6 28.7 51.5 7.7 59.2 35.3 78.8 50.6 26.8 36.0 59.6 39.5 0.0 3.5 3.5 2.8 5.6 3.1 2.2 3.3 3.1 6.5 1.9 2.1 2.7 0.1 1.4 8.6 5.0 2.9 2.4 7.3 6.5 5.4 8.6 7.4 7.9 7.9 6.5 6.9 6.1 7.6 9.0 11.3 9.6 5.8 12.1 22.7 5.9 7.4 8.2 9.6 12.0 13.0 8.5 5.5 11.5 9.0 14.7 18.8 20.3 12.5 28.5 1.9 19.1 10.3 11.5 9.8 9.0 18.6 11.1 11.2 18.4 18.2 10.2 31.6 13.6 5.7 16.2 10.8 13.2 20.0 5.0 11.0 22.9 12.2 12.2 9.5 5.1 14.0 18.3 7.2 7.5 13.6 12.6 8.2 9.0 11.0 15.6 22.4 9.8 50.4 11.9 28.6 6.6 12.8 10.8 6.6 9.2 11.4 14.7 14.6 12.6 6.1 15.3 13.9 20.2 22.2 6.4 ATP23 "KUB3, XRCC6BP1" ENSG00000166896 "ATP23 metallopeptidase and ATP synthase assembly factor homolog" Q9Y6H3 12 57906039-57959148 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.8" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 12.7;Cytotrophoblasts: 14.4;Distal tubular cells: 17.6;Extravillous trophoblasts: 15.2;Proximal tubular cells: 26.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.6" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.6" "Cell line enhanced" "Detected in some" "A549: 1.0;Karpas-707: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035804, HPA043204" Uncertain Enhanced "Vesicles,Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Plasma membrane" "Cell Junctions, Cytosol" "HPA035804: AB_10601026, HPA043204: AB_2678361" "unprognostic (2.56e-1)" "unprognostic (1.31e-2)" "unprognostic (8.82e-2)" "unprognostic (2.92e-2)" "unprognostic (2.30e-2)" "unprognostic (6.16e-2)" "unprognostic (1.20e-1)" "unprognostic (5.28e-2)" "unprognostic (5.41e-3)" "unprognostic (1.03e-2)" "unprognostic (1.24e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.44e-5)" "unprognostic (4.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.80e-1)" "unprognostic (2.27e-1)" 7.5 4.9 0.6 0.4 0.5 0.1 5.6 0.6 0.9 4.1 0.5 8.1 0.2 3.1 0.0 5.6 3.2 0.0 4.6 1.0 0.3 4.0 5.2 2.6 0.1 0.4 0.2 3.1 5.9 0.0 2.8 0.1 0.4 3.3 0.0 0.5 3.6 0.0 12.4 4.4 4.3 0.0 0.3 3.2 4.2 27.8 0.5 0.0 3.5 0.0 0.1 4.7 4.0 0.3 0.6 1.0 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.9 0.2 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.6 2.6 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.3 0.6 0.8 0.1 0.0 0.4 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.3 0.0 0.4 0.0 0.0 0.4 0.0 0.6 0.1 0.2 0.0 0.2 0.2 0.2 0.2 0.1 0.3 0.0 0.3 0.2 0.2 1.6 0.1 0.1 0.1 0.1 0.0 0.6 0.5 0.6 0.9 1.0 0.3 0.4 0.2 0.4 0.3 0.5 0.3 8.0 0.0 9.2 0.0 2.3 0.0 0.0 0.0 0.0 0.0 7.4 12.7 0.0 0.0 1.8 3.7 0.0 14.4 4.2 0.0 17.6 6.1 0.0 5.6 4.9 2.8 0.0 0.0 0.0 10.7 15.2 2.3 0.0 6.0 11.4 6.8 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.9 0.0 0.0 26.1 0.7 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 3.4 3.0 9.5 0.0 0.0 ATP6V0A1 "a1, ATP6N1, ATP6N1A, Stv1, Vph1, VPP1" ENSG00000033627 "ATPase H+ transporting V0 subunit a1" Q93050 17 42458844-42522582 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 130.7" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 294.0;Rod photoreceptor cells: 403.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022144 Enhanced Approved "Nuclear speckles,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus, Vesicles" "Nuclear speckles, Cytosol" "HPA022144: AB_1845189" "unprognostic (3.93e-2)" "unprognostic (2.02e-1)" "unprognostic (4.35e-2)" "unprognostic (2.22e-2)" "unprognostic (1.60e-2)" "unprognostic (8.69e-2)" "unprognostic (1.84e-2)" "unprognostic (8.82e-2)" "unprognostic (1.47e-1)" "unprognostic (1.85e-1)" "prognostic favorable (2.05e-4)" "unprognostic (3.25e-1)" "prognostic favorable (1.28e-4)" "unprognostic (3.07e-1)" "unprognostic (3.68e-2)" "unprognostic (2.62e-2)" "prognostic unfavorable (6.90e-4)" 17.7 28.2 30.6 18.0 35.2 21.5 16.3 16.8 42.7 13.4 0.0 22.1 34.6 20.9 19.6 17.4 17.1 22.7 18.9 43.6 44.1 37.4 21.0 24.1 13.1 25.6 26.2 20.0 17.4 86.0 39.0 21.2 34.6 17.4 20.5 130.7 13.5 18.6 59.3 28.1 24.3 21.5 12.1 21.8 16.3 18.7 30.9 15.2 30.3 25.3 14.9 11.9 12.8 27.2 18.4 37.0 22.1 40.1 36.5 31.7 12.9 12.7 23.3 26.4 34.2 23.9 39.9 3.4 22.6 26.2 36.2 38.7 34.5 21.5 30.4 28.3 36.2 29.2 27.3 19.0 22.7 12.8 50.9 23.5 30.3 42.4 18.0 32.6 18.9 13.2 108.0 111.3 39.7 15.8 5.1 11.3 14.3 23.9 0.4 0.2 23.0 51.2 30.2 14.4 60.9 32.0 19.7 17.7 37.1 28.8 43.0 19.0 11.4 22.3 0.9 33.0 15.3 45.0 66.1 6.8 29.7 0.2 26.5 21.6 14.5 11.2 1.0 4.4 1.6 4.7 0.7 0.2 12.2 7.3 1.2 0.9 18.7 0.1 3.3 6.2 3.7 6.6 30.6 35.2 16.8 42.7 43.6 44.1 25.6 26.2 34.6 12.1 30.9 27.2 20.0 19.2 48.0 47.0 23.0 19.8 56.7 15.7 32.5 164.8 15.7 16.5 21.1 28.6 18.3 14.7 294.0 34.3 16.7 46.2 11.7 16.3 4.0 32.8 27.4 22.2 84.9 45.8 125.0 18.5 15.7 31.0 23.4 74.0 24.1 74.5 16.4 37.8 53.8 95.9 112.3 27.3 12.2 37.8 29.2 3.9 17.4 42.8 40.9 38.4 17.7 59.3 3.1 61.3 80.5 24.2 37.6 23.7 13.8 32.7 56.9 32.5 11.4 403.4 6.6 39.4 32.3 38.8 18.2 21.7 20.2 99.9 6.9 35.0 24.5 14.9 ATP6V0A2 "a2, ATP6a2, ATP6N1D, J6B7, Stv1, TJ6, TJ6M, TJ6s, Vph1" ENSG00000185344 "ATPase H+ transporting V0 subunit a2" Q9Y487 12 123712353-123761755 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 13.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 51.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044279 Approved Supported "Vesicles,Plasma membrane,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "Vesicles, Focal adhesion sites" "HPA044279: AB_10961274" "unprognostic (2.60e-1)" "unprognostic (8.79e-3)" "unprognostic (3.60e-2)" "unprognostic (1.50e-1)" "unprognostic (2.70e-1)" "unprognostic (2.29e-2)" "unprognostic (2.06e-4)" "unprognostic (1.40e-1)" "unprognostic (3.77e-2)" "unprognostic (1.75e-1)" "unprognostic (8.85e-3)" "unprognostic (1.63e-1)" "unprognostic (1.26e-1)" "unprognostic (7.48e-2)" "unprognostic (1.12e-1)" "unprognostic (3.47e-1)" "unprognostic (1.58e-1)" 6.6 4.4 5.6 7.0 6.2 10.4 5.7 7.4 6.5 4.7 6.9 5.5 8.7 6.0 3.9 4.3 4.8 3.8 4.7 6.0 6.0 3.8 4.2 6.3 8.3 6.6 5.8 4.1 5.7 3.7 4.9 3.7 6.5 4.7 5.8 6.7 7.6 4.0 6.5 9.4 7.0 5.1 5.6 6.6 8.8 4.9 6.2 7.5 4.8 3.5 8.2 5.3 4.5 7.9 4.8 10.3 12.0 17.8 9.2 7.0 6.7 6.2 6.2 5.4 5.8 6.9 2.7 18.0 4.2 7.6 5.5 9.0 16.1 6.2 4.5 11.4 10.2 27.9 9.2 5.4 10.2 16.8 51.0 6.7 4.4 5.9 7.4 9.0 5.0 15.0 14.5 3.4 8.1 8.4 15.4 24.8 11.5 6.6 6.5 15.7 9.9 6.4 8.3 10.4 7.2 13.6 9.3 6.9 9.4 6.6 5.9 14.4 8.3 8.0 3.1 10.8 9.1 10.8 12.8 14.9 9.4 12.1 6.5 6.3 0.7 13.7 1.7 0.9 1.0 0.9 1.7 1.5 0.8 3.7 1.6 1.8 2.0 1.7 1.5 2.8 1.0 0.8 5.6 6.2 7.4 6.5 6.0 6.0 6.6 5.8 6.5 5.6 6.2 7.9 13.0 6.4 11.0 3.9 20.4 10.1 10.8 4.6 11.4 20.5 7.9 5.3 8.8 12.8 8.3 9.2 12.5 5.2 27.9 17.9 0.0 8.1 10.2 11.0 11.9 10.6 13.2 50.3 21.2 10.9 5.7 11.3 18.3 12.3 75.3 8.7 18.2 11.4 8.4 11.8 19.3 9.8 2.0 9.4 17.2 4.5 8.7 11.3 1.8 7.5 13.2 9.0 25.7 10.6 17.1 9.2 9.0 9.4 19.7 15.7 11.1 4.0 13.5 28.8 6.6 12.4 10.9 23.6 12.6 9.6 14.2 6.8 21.8 5.7 11.4 11.4 ATP6V0D2 "ATP6D2, FLJ38708, VMA6" ENSG00000147614 "ATPase H+ transporting V0 subunit d2" Q8N8Y2 8 85987323-86154225 "Metabolic proteins, Predicted intracellular proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 60.5" "Cell type enriched" "Detected in some" 6 "Distal tubular cells: 209.4" "Cancer enriched" "Detected in many" 9 "renal cancer: 36.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "SK-MEL-30: 3.3;SuSa: 5.8;U-87 MG: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA055327, HPA058496" Enhanced Approved Vesicles NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA055327: AB_2682784, HPA058496: " "unprognostic (3.79e-2)" "unprognostic (1.59e-1)" "unprognostic (1.78e-1)" "unprognostic (1.22e-1)" "unprognostic (8.50e-2)" "unprognostic (8.43e-3)" "unprognostic (5.36e-5)" "unprognostic (4.02e-2)" "unprognostic (1.16e-1)" "unprognostic (7.75e-3)" "unprognostic (2.32e-2)" "unprognostic (1.61e-1)" "prognostic favorable (2.20e-6)" "unprognostic (8.58e-2)" "unprognostic (1.77e-2)" "unprognostic (3.67e-1)" "unprognostic (1.97e-2)" 0.3 0.0 0.6 0.7 1.4 1.9 0.8 0.4 0.7 0.4 0.4 3.1 1.6 0.3 1.4 0.7 0.0 0.5 0.4 0.5 0.7 60.5 0.4 2.6 1.3 0.6 1.1 0.0 0.4 1.3 0.0 0.8 0.6 1.4 3.5 14.0 1.1 2.5 0.0 1.7 1.3 0.4 0.3 1.1 0.3 0.2 1.0 0.5 1.0 0.0 1.1 0.5 0.0 1.4 0.4 0.6 0.3 0.4 0.0 0.3 1.3 0.0 0.0 0.6 0.1 0.0 0.2 0.1 0.1 0.0 1.4 1.2 0.4 0.9 0.2 0.2 0.0 0.5 0.7 0.1 0.0 0.4 0.6 0.3 0.0 0.2 0.4 1.1 0.0 0.1 0.2 0.3 0.3 0.0 0.0 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.6 2.0 0.1 0.0 0.4 3.3 5.8 0.9 0.0 0.2 0.3 0.4 0.2 0.3 0.2 0.1 0.3 5.1 0.3 0.4 0.7 0.2 0.1 0.2 0.1 0.1 0.2 0.2 0.1 0.1 0.4 0.2 0.2 1.0 0.5 0.2 0.4 0.2 0.1 0.6 1.4 0.4 0.7 0.5 0.7 0.6 1.1 0.6 0.3 1.0 1.4 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.1 0.0 0.4 0.1 0.0 0.4 0.0 0.1 7.3 31.3 0.0 0.0 0.0 209.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.0 0.0 0.2 0.0 30.5 0.0 1.1 0.0 0.0 6.9 0.0 0.0 0.0 1.5 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.3 0.0 1.0 0.0 11.4 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.2 ATP6V1A "ATP6A1, ATP6V1A1, VA68, Vma1, VPP2" ENSG00000114573 "ATPase H+ transporting V1 subunit A" P38606 3 113747033-113812056 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Translocase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 463.7;Late spermatids: 870.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 79.2" "Group enriched" "Detected in all" 6 "dendritic cells: 38.8;granulocytes: 79.2;monocytes: 37.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006910, HPA035084" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA 700000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Cytosol" Nucleoplasm "CAB006910: , HPA035084: AB_2674454" "unprognostic (1.32e-1)" "unprognostic (8.68e-2)" "unprognostic (5.87e-2)" "unprognostic (4.70e-2)" "unprognostic (1.36e-1)" "unprognostic (2.00e-1)" "unprognostic (3.43e-2)" "unprognostic (2.90e-2)" "unprognostic (1.42e-1)" "unprognostic (2.25e-1)" "unprognostic (1.36e-2)" "unprognostic (5.19e-3)" "prognostic favorable (3.82e-12)" "unprognostic (8.82e-2)" "unprognostic (2.46e-3)" "unprognostic (2.43e-1)" "unprognostic (1.52e-2)" 18.1 32.2 40.1 21.6 46.4 16.6 24.5 14.7 53.0 25.3 62.4 22.1 18.5 14.2 15.1 22.7 19.0 20.9 9.0 47.5 58.5 92.7 36.4 24.5 25.1 39.6 23.0 11.3 20.9 60.1 17.1 24.5 39.0 20.9 22.5 58.7 37.5 14.9 7.9 25.0 15.9 15.8 16.9 26.5 22.1 18.1 28.4 22.9 40.8 11.0 28.0 19.6 14.2 21.9 61.7 27.4 33.9 29.7 70.0 30.9 36.0 32.7 49.4 33.7 46.1 52.4 48.3 50.4 75.5 48.0 37.3 39.1 77.5 43.2 43.8 23.1 21.4 44.8 39.3 40.6 57.6 33.2 50.0 42.0 29.1 43.7 30.2 52.0 55.7 25.1 52.0 37.0 50.5 40.5 24.4 14.9 42.8 42.9 34.3 20.8 24.6 57.4 92.5 58.0 65.4 24.1 57.3 38.6 44.9 46.4 58.5 26.6 51.4 31.1 23.1 21.7 19.8 38.4 44.5 46.2 61.1 41.2 35.3 26.8 37.0 12.8 6.3 27.7 5.9 8.2 5.6 6.0 38.8 6.8 5.4 6.2 79.2 9.2 23.9 10.8 8.1 16.7 40.1 46.4 14.7 53.0 47.5 58.5 39.6 23.0 39.0 16.9 28.4 21.9 18.8 28.9 35.0 43.4 24.2 30.3 15.9 30.3 23.9 94.1 27.9 17.1 10.4 31.5 32.9 99.3 41.7 22.0 20.8 38.3 82.2 29.5 463.7 41.7 24.5 26.8 55.8 49.6 119.4 27.5 22.6 17.9 20.9 100.6 10.8 19.4 36.0 74.3 74.3 101.0 107.7 25.4 197.4 104.7 73.3 870.3 18.0 70.9 46.2 34.7 82.8 45.6 11.3 54.3 53.2 27.1 30.5 23.0 23.6 25.6 24.1 80.8 38.3 44.4 6.6 15.3 21.6 28.7 15.7 40.8 47.9 43.9 19.0 25.8 27.2 26.8 ATP6V1B2 "ATP6B2, HO57, VATB, Vma2, VPP3" ENSG00000147416 "ATPase H+ transporting V1 subunit B2" P21281 8 20197381-20226819 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Hydrolase "Deafness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 256.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1130.7" "Group enriched" "Detected in all" 10 "dendritic cells: 336.8;granulocytes: 1130.7;monocytes: 682.0" "Cell line enhanced" "Detected in all" "SK-MEL-30: 317.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008147 Enhanced Supported Vesicles NA NA 310000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 58: Brain - Synaptic function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA008147: AB_1845195" "unprognostic (1.90e-1)" "unprognostic (7.24e-3)" "unprognostic (3.62e-2)" "unprognostic (2.57e-1)" "unprognostic (2.84e-2)" "unprognostic (5.59e-3)" "unprognostic (1.76e-2)" "unprognostic (3.78e-2)" "unprognostic (4.68e-2)" "unprognostic (4.23e-3)" "unprognostic (1.29e-2)" "unprognostic (1.34e-1)" "prognostic favorable (8.41e-4)" "unprognostic (2.41e-1)" "unprognostic (2.09e-2)" "unprognostic (2.47e-2)" "unprognostic (5.25e-2)" 46.4 76.4 112.6 71.9 111.2 45.7 35.3 72.8 126.0 30.1 72.5 38.0 43.9 29.4 31.0 51.3 32.8 39.0 38.2 124.0 135.5 145.8 49.2 72.7 54.1 103.4 120.0 27.5 34.5 71.4 74.5 50.5 138.2 28.1 43.0 205.7 40.4 27.0 66.7 62.5 57.8 40.1 74.8 66.1 32.8 67.8 100.3 50.2 33.4 64.7 48.9 44.5 36.1 99.5 44.2 71.5 87.4 29.2 117.7 72.3 79.1 96.6 61.5 121.5 125.2 81.7 25.4 77.7 38.4 93.1 123.7 36.8 70.1 64.6 129.0 32.9 47.2 54.2 29.9 63.6 137.6 39.0 108.0 65.0 57.9 76.0 69.3 134.1 77.2 101.2 82.0 72.8 132.5 25.0 114.6 46.2 65.6 64.6 31.5 46.6 113.4 40.8 112.9 68.2 68.0 97.9 46.9 62.7 317.9 72.4 81.6 70.7 82.8 61.1 46.3 101.9 78.5 29.4 42.7 90.9 84.6 91.6 158.4 183.7 682.0 485.9 52.9 618.6 57.7 50.2 54.1 56.8 336.8 44.5 54.4 53.7 1130.7 50.8 576.1 82.7 73.0 622.6 112.6 111.2 72.8 126.0 124.0 135.5 103.4 120.0 138.2 74.8 100.3 99.5 16.6 25.6 20.7 20.5 28.1 58.0 28.4 52.1 33.0 106.1 18.5 15.6 17.6 25.8 28.8 29.5 102.2 109.2 38.9 23.3 80.3 43.2 40.8 20.2 13.6 24.1 74.4 35.8 64.3 38.5 56.4 38.8 25.0 35.9 22.2 22.3 25.7 34.7 178.5 190.1 68.0 21.4 36.7 185.2 178.7 24.4 19.6 167.6 104.9 30.0 169.1 51.5 20.6 27.6 29.0 45.2 19.7 28.2 20.7 17.4 75.0 256.7 18.0 137.8 13.1 29.3 34.2 121.6 55.3 43.3 71.6 124.6 27.1 23.1 24.7 20.1 ATP8A1 ATPIA ENSG00000124406 "ATPase phospholipid transporting 8A1" Q9Y2Q0 4 42408373-42657105 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.5" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1218.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 13.5" "Region enhanced" "Detected in all" "white matter: 84.5" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 27.5;Daudi: 46.3;HEL: 16.4;REH: 16.1;SH-SY5Y: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052935 Enhanced Supported Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA052935: AB_2681992" "unprognostic (8.63e-2)" "unprognostic (3.43e-2)" "unprognostic (1.16e-2)" "unprognostic (7.61e-2)" "unprognostic (6.59e-2)" "unprognostic (6.82e-3)" "unprognostic (7.69e-2)" "unprognostic (2.02e-3)" "unprognostic (3.99e-1)" "unprognostic (2.99e-3)" "unprognostic (4.39e-2)" "unprognostic (9.71e-2)" "prognostic favorable (5.54e-10)" "unprognostic (2.43e-1)" "unprognostic (3.25e-1)" "unprognostic (8.21e-2)" "unprognostic (2.25e-1)" 2.8 8.9 5.8 9.5 26.7 23.4 3.7 3.6 18.3 2.1 0.0 12.8 4.2 2.4 12.2 2.2 2.4 2.5 8.4 14.5 11.7 3.8 1.7 11.8 15.0 9.5 4.4 16.2 7.0 36.0 2.2 2.4 9.5 8.3 11.7 19.4 4.4 5.3 10.0 1.7 8.9 2.8 18.1 9.0 12.5 2.1 9.5 9.9 39.7 15.6 11.8 2.5 1.5 84.5 0.0 0.1 0.4 27.5 0.1 0.1 0.1 0.1 0.0 0.0 0.0 3.0 0.4 46.3 12.6 0.2 0.0 2.4 6.5 0.1 0.0 7.4 4.5 16.4 1.6 0.7 0.1 4.0 0.3 0.4 0.0 0.0 0.0 0.6 0.2 10.3 0.0 5.1 0.0 2.0 6.0 1.4 2.0 1.9 0.6 16.1 0.0 5.3 9.5 0.6 4.9 14.8 0.3 9.4 0.0 1.1 3.1 0.0 0.4 0.0 2.0 0.5 0.0 1.7 0.0 9.4 0.7 5.6 0.2 0.0 0.6 0.6 3.7 0.2 1.9 1.5 1.1 4.1 0.6 2.5 1.7 4.4 0.5 2.2 2.5 2.4 1.0 0.6 5.8 26.7 3.6 18.3 14.5 11.7 9.5 4.4 9.5 18.1 9.5 84.5 26.1 28.9 80.1 136.1 23.3 1.5 1.8 0.6 2.2 19.7 4.0 1.5 14.4 0.0 5.3 5.5 81.3 0.0 52.9 48.4 3.9 0.2 4.6 1.3 1.3 13.6 84.6 13.9 295.9 2.5 0.1 4.8 19.9 4.2 8.2 26.5 16.8 1.1 1.6 62.2 255.9 28.6 0.0 8.8 4.6 2.9 3.4 8.9 3.6 31.9 5.1 2.2 33.0 144.8 1218.1 0.6 10.2 1.9 37.6 9.6 45.6 2.0 0.3 38.1 0.0 6.3 2.7 1.5 3.6 5.0 1.4 0.0 51.6 8.6 25.0 3.0 ATP8B4 "ATPIM, KIAA1939" ENSG00000104043 "ATPase phospholipid transporting 8B4 (putative)" Q8TF62 15 49858238-50182817 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "bone marrow: 78.1" "Cell type enriched" "Detected in many" 6 "Microglial cells: 248.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 15.2;NK-cell: 11.0" "Group enriched" "Detected in many" 5 "granulocytes: 15.2;NK-cells: 11.0" "Cell line enhanced" "Detected in some" "HMC-1: 40.2;NB-4: 19.2;THP-1: 26.7;U-937: 103.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA040254 Approved Uncertain Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" Cytosol "HPA040254: AB_10673028" "unprognostic (6.45e-3)" "unprognostic (3.83e-2)" "unprognostic (5.39e-2)" "unprognostic (2.96e-3)" "unprognostic (3.25e-1)" "unprognostic (6.51e-3)" "unprognostic (1.03e-1)" "unprognostic (4.87e-3)" "unprognostic (1.64e-2)" "unprognostic (5.11e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-2)" "unprognostic (5.99e-2)" "unprognostic (5.12e-2)" "unprognostic (1.20e-2)" "unprognostic (1.53e-1)" "unprognostic (2.08e-1)" 1.4 1.1 2.3 2.5 2.4 78.1 0.7 3.5 6.5 1.5 3.0 1.1 0.7 6.4 4.2 0.5 3.1 2.2 0.4 4.5 2.9 1.2 1.6 1.1 1.0 2.5 2.6 0.4 0.5 0.2 0.3 3.5 2.8 0.6 1.7 0.1 0.5 0.8 0.1 0.3 1.3 3.1 3.1 2.6 0.6 0.4 2.4 0.5 0.1 0.1 1.0 1.4 0.4 4.9 0.1 0.6 0.0 0.0 0.0 0.7 0.2 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.5 0.5 0.2 0.0 0.2 12.2 0.0 7.3 1.7 0.1 0.0 13.6 40.2 0.7 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 19.2 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.1 1.5 0.1 1.2 0.0 0.0 0.1 0.0 26.7 0.0 0.0 0.3 1.0 0.0 0.1 0.0 0.0 1.3 103.7 0.0 15.2 2.0 3.8 0.4 1.2 0.1 0.0 0.0 0.1 2.7 0.0 0.0 0.0 0.8 11.0 0.4 0.0 0.0 0.9 2.3 2.4 3.5 6.5 4.5 2.9 2.5 2.6 2.8 3.1 2.4 4.9 1.7 0.0 1.9 1.6 0.8 1.5 0.1 0.2 0.6 0.6 0.2 0.6 1.3 0.0 0.1 0.0 0.0 5.4 12.5 0.3 0.0 0.0 27.6 0.3 1.7 1.0 0.0 12.2 20.3 0.0 1.8 8.1 3.1 0.2 19.7 0.0 1.1 3.7 16.4 0.0 17.5 0.3 2.0 37.0 17.7 25.3 1.8 27.0 1.8 248.3 6.3 0.5 15.5 1.0 2.1 0.0 0.1 0.7 4.8 2.3 0.7 1.2 0.7 0.2 0.0 1.0 7.0 0.5 0.6 0.6 0.3 2.9 13.4 1.1 0.2 0.3 ATPSCKMT "FAM173B, JS-2" ENSG00000150756 "ATP synthase c subunit lysine N-methyltransferase" Q6P4H8 5 10225507-10249897 "Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 7.1;Cytotrophoblasts: 5.9;Extravillous trophoblasts: 4.1;Fibroblasts: 2.3;Hofbauer cells: 7.8;Syncytiotrophoblasts: 2.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SiHa: 69.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074513 Approved Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 20: HeLa - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" "HPA074513: AB_2686698" "prognostic unfavorable (1.32e-6)" "unprognostic (8.87e-3)" "unprognostic (1.23e-3)" "unprognostic (1.20e-1)" "unprognostic (9.24e-2)" "unprognostic (1.41e-2)" "unprognostic (2.07e-2)" "unprognostic (1.53e-1)" "unprognostic (2.54e-2)" "unprognostic (6.90e-3)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (1.14e-2)" "unprognostic (1.79e-1)" "unprognostic (9.06e-2)" "unprognostic (5.61e-2)" "unprognostic (1.03e-1)" 8.5 10.3 12.4 5.4 13.0 3.9 6.6 13.5 15.5 5.7 13.8 7.4 6.1 6.9 9.1 5.8 6.5 7.2 6.9 11.7 14.3 9.0 9.9 5.1 7.8 13.2 13.6 6.3 5.1 17.1 9.9 4.1 13.2 8.8 8.7 5.0 7.4 8.3 6.7 5.8 5.6 7.5 12.0 4.5 6.2 5.7 13.4 6.9 8.8 7.4 6.8 7.1 5.3 14.8 14.1 13.3 13.9 13.8 12.7 9.8 4.8 20.4 9.2 9.2 8.0 14.1 21.0 16.8 35.2 13.0 27.7 9.6 19.6 17.0 15.8 30.9 13.2 14.5 47.6 11.4 9.7 22.8 16.5 9.1 18.3 17.4 5.5 11.8 19.7 17.8 19.9 18.0 26.6 11.9 11.6 20.2 9.1 29.9 17.4 15.8 9.7 15.9 24.6 16.5 11.1 10.9 69.3 24.5 12.2 10.5 25.7 23.2 11.2 22.4 13.9 14.2 14.9 11.9 14.5 19.7 14.1 25.3 9.0 3.2 5.8 8.1 4.3 6.7 5.3 3.8 4.2 5.5 5.8 2.6 4.1 5.4 2.2 3.8 5.5 2.1 5.4 2.6 12.4 13.0 13.5 15.5 11.7 14.3 13.2 13.6 13.2 12.0 13.4 14.8 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 5.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 4.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 2.6 0.2 0.0 0.0 0.0 ATXN7L2 "FLJ00381, MGC46534" ENSG00000162650 "Ataxin 7 like 2" Q5T6C5 1 109483479-109492804 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 7.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029827, HPA054952" Uncertain Approved "Nucleoli rim,Vesicles,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoli rim" "Vesicles, Cytosol" "HPA029827: AB_10602390, HPA054952: AB_2682647" "unprognostic (4.53e-2)" "unprognostic (6.55e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.65e-4)" "unprognostic (3.90e-2)" "unprognostic (4.61e-5)" "unprognostic (2.40e-4)" "unprognostic (1.75e-1)" "unprognostic (3.53e-2)" "unprognostic (8.07e-2)" "unprognostic (2.77e-4)" "unprognostic (2.85e-2)" "prognostic unfavorable (1.19e-8)" "unprognostic (3.70e-2)" "unprognostic (1.08e-1)" "unprognostic (8.27e-2)" "unprognostic (3.94e-3)" 1.2 2.7 1.3 0.7 1.4 3.0 1.1 1.3 2.7 1.9 0.7 1.2 0.5 2.0 0.1 1.2 1.4 0.8 1.3 2.5 1.0 2.0 1.7 1.0 0.9 1.1 1.1 1.9 1.0 0.3 2.1 0.4 1.0 1.2 0.1 0.1 0.9 0.4 7.9 1.7 1.4 0.3 0.9 2.2 1.0 5.2 1.3 1.5 2.2 1.6 0.5 1.3 1.2 1.4 1.8 1.4 0.9 3.6 1.2 2.2 2.5 1.3 1.6 2.6 1.8 3.0 1.2 4.8 2.0 1.6 0.7 2.1 1.9 1.8 0.3 4.4 2.7 2.6 3.0 1.3 0.8 4.0 6.0 2.4 0.9 2.8 0.0 1.1 0.6 5.1 4.5 2.6 0.5 5.8 7.1 5.2 5.6 1.9 2.0 4.9 2.3 3.4 0.9 1.9 8.4 3.4 1.4 4.5 2.2 0.2 0.8 4.1 0.3 1.9 5.5 1.8 5.3 1.7 1.2 4.6 2.2 3.3 4.8 0.0 0.8 1.1 2.3 1.1 2.2 1.0 1.9 2.5 0.6 1.3 1.7 1.6 0.9 1.4 0.8 0.4 1.8 1.0 1.3 1.4 1.3 2.7 2.5 1.0 1.1 1.1 1.0 0.9 1.3 1.4 1.0 0.0 0.5 5.5 2.4 0.6 1.4 1.3 1.8 3.5 1.4 0.9 1.9 1.5 2.1 1.8 2.1 1.4 1.6 1.4 0.0 1.4 3.5 0.8 2.4 1.3 1.8 0.8 4.7 1.8 1.5 1.7 1.1 1.0 4.5 2.3 1.8 1.1 0.6 3.3 3.9 1.1 2.0 1.2 1.0 1.0 1.2 0.6 0.0 1.0 0.4 0.9 1.0 3.0 1.8 1.5 1.4 1.5 2.9 0.7 0.7 0.6 0.3 2.0 0.0 2.5 4.8 4.2 4.9 1.3 0.9 3.1 2.6 3.5 0.9 0.9 AUP1 ENSG00000115307 "AUP1 lipid droplet regulating VLDL assembly factor" Q9Y679 2 74526645-74529760 "Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007674 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Vesicles" "HPA007674: AB_1078251" "unprognostic (1.09e-1)" "unprognostic (2.95e-2)" "unprognostic (1.97e-2)" "unprognostic (2.11e-2)" "unprognostic (5.97e-2)" "unprognostic (2.96e-3)" "prognostic unfavorable (2.29e-4)" "unprognostic (2.00e-1)" "unprognostic (2.73e-1)" "unprognostic (3.79e-2)" "unprognostic (2.77e-1)" "unprognostic (3.65e-1)" "prognostic unfavorable (2.97e-9)" "unprognostic (9.68e-2)" "unprognostic (1.59e-1)" "unprognostic (3.35e-1)" "unprognostic (3.96e-2)" 48.0 42.2 68.0 44.4 69.0 78.8 52.6 71.0 85.8 56.0 72.1 76.9 70.6 38.7 78.6 49.9 45.3 46.0 38.4 67.6 71.0 48.8 106.9 48.7 41.3 73.0 69.6 38.1 127.3 77.6 2.1 60.6 69.7 38.9 81.0 32.4 89.1 46.3 57.7 42.3 68.5 55.8 70.5 39.5 56.7 24.5 70.1 42.5 50.9 66.6 51.5 69.6 20.7 72.1 114.2 133.4 55.3 87.5 183.1 107.7 124.9 89.1 152.6 122.3 77.3 196.9 130.6 126.4 61.9 126.5 210.3 143.4 140.4 115.1 98.5 100.1 128.7 153.6 71.2 180.7 181.5 97.8 127.9 128.5 256.7 174.4 198.6 101.1 117.3 105.1 202.2 164.5 134.0 124.6 79.0 200.6 111.4 298.3 111.9 95.3 150.0 270.3 139.3 90.9 80.7 79.6 65.2 200.4 162.2 70.8 90.2 156.7 59.3 162.9 97.2 50.6 146.8 87.9 88.1 120.4 129.6 155.9 184.9 113.8 132.9 108.9 81.9 169.3 89.6 90.6 81.0 82.0 124.6 113.9 72.9 75.8 68.8 85.3 144.7 118.3 107.9 132.2 68.0 69.0 71.0 85.8 67.6 71.0 73.0 69.6 69.7 70.5 70.1 72.1 64.8 67.3 44.6 22.5 97.3 73.2 120.7 161.1 80.8 31.7 71.4 59.6 34.9 74.4 108.1 68.0 14.6 140.0 86.6 150.4 23.5 125.2 24.3 36.2 50.1 74.9 73.8 72.4 17.7 208.7 217.3 73.0 121.8 58.7 89.9 57.3 50.0 114.3 161.8 37.0 16.1 127.7 136.3 83.5 95.5 29.7 44.4 95.2 97.8 17.8 67.2 74.5 72.1 14.6 23.4 153.1 141.3 38.0 229.9 141.1 196.0 59.6 46.6 43.2 59.2 60.0 104.2 85.9 64.6 95.7 78.7 223.8 77.6 68.4 134.2 143.9 AXIN1 PPP1R49 ENSG00000103126 "Axin 1" O15169 16 287440-352723 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012987 Approved Supported Nucleoli,Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoli, Vesicles" "CAB012987: AB_2533178" "unprognostic (3.81e-2)" "unprognostic (1.56e-1)" "unprognostic (1.90e-1)" "unprognostic (7.64e-2)" "unprognostic (1.90e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (3.38e-5)" "unprognostic (1.23e-1)" "unprognostic (3.58e-1)" "unprognostic (1.56e-1)" "unprognostic (4.58e-2)" "unprognostic (2.02e-2)" "unprognostic (1.57e-1)" "unprognostic (4.41e-2)" "unprognostic (1.94e-1)" "unprognostic (1.23e-2)" "unprognostic (1.03e-1)" 11.9 9.3 10.5 9.2 10.8 23.0 11.5 14.8 12.5 12.9 9.1 17.1 12.3 13.2 3.1 16.3 11.8 6.2 11.6 10.0 9.2 11.6 11.2 13.7 10.5 10.2 10.2 13.8 13.0 7.2 12.6 5.8 9.8 12.9 6.9 2.6 11.5 6.0 21.1 20.1 15.0 5.4 9.2 15.0 12.9 11.8 10.1 12.5 11.9 7.0 6.6 14.5 13.1 11.9 18.1 25.6 13.4 23.7 9.8 9.0 28.0 11.9 10.8 16.1 13.8 37.9 20.4 27.7 18.0 12.3 19.4 25.4 21.1 18.5 7.2 27.5 34.6 18.0 21.9 27.6 16.6 20.9 19.3 9.0 31.7 16.6 20.3 14.1 10.7 19.8 45.6 14.8 7.4 48.1 22.7 14.5 30.6 21.6 15.4 42.4 12.2 38.8 12.2 10.5 30.4 18.6 22.6 24.9 38.3 10.0 16.5 26.1 12.4 15.9 17.0 18.5 17.5 17.3 18.1 34.2 7.5 13.7 15.9 1.2 0.9 5.0 8.3 0.8 7.6 1.5 2.4 5.8 0.7 1.2 2.4 3.4 2.7 3.5 0.6 1.2 2.6 2.3 10.5 10.8 14.8 12.5 10.0 9.2 10.2 10.2 9.8 9.2 10.1 11.9 7.9 3.2 8.6 4.9 5.7 18.4 7.6 8.5 5.7 4.3 11.2 9.5 4.9 5.7 7.2 3.7 0.0 3.5 30.1 27.4 0.0 7.2 1.4 10.2 7.0 6.3 10.8 8.6 18.5 6.9 27.5 6.7 15.3 14.4 10.8 10.5 5.7 5.1 7.5 5.0 12.7 15.1 6.1 6.2 9.0 2.1 5.3 6.7 10.6 1.0 5.7 4.5 28.8 8.5 8.9 11.0 12.2 4.9 7.0 13.4 11.1 2.4 7.7 5.7 13.1 8.7 7.6 5.5 8.8 7.2 15.2 3.7 12.4 5.0 15.7 10.5 AXL "ARK, JTK11, Tyro7, UFO" ENSG00000167601 "AXL receptor tyrosine kinase" P30530 19 41219223-41261766 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Differentiation, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Oncogene, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 147.2;Kupffer cells: 187.5;Langerhans cells: 185.5;Prostatic glandular cells: 123.4;Sertoli cells: 210.4;Smooth muscle cells: 171.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 11.1;plasmacytoid DC: 25.7" "Group enriched" "Detected in many" 12 "dendritic cells: 25.7;NK-cells: 11.1" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 501.2;U-251 MG: 540.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032501, HPA037422, HPA037423, HPA075217" Uncertain Supported "Vesicles,Plasma membrane,Actin filaments" NA Yes 12100000 72000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Vesicles, Actin filaments" "CAB032501: AB_2062572, HPA037422: AB_10672347, HPA037423: AB_2675470, HPA075217: " "unprognostic (2.20e-1)" "unprognostic (2.02e-1)" "unprognostic (6.79e-3)" "unprognostic (1.01e-1)" "unprognostic (1.40e-1)" "unprognostic (8.49e-3)" "unprognostic (2.42e-1)" "unprognostic (1.74e-1)" "unprognostic (3.15e-2)" "unprognostic (2.82e-2)" "unprognostic (9.57e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (1.16e-3)" "unprognostic (1.52e-2)" "unprognostic (5.56e-2)" "unprognostic (4.83e-3)" 43.6 18.8 17.5 15.5 22.6 1.7 26.6 19.7 17.7 36.1 12.4 42.5 11.7 34.4 8.7 17.6 25.4 22.4 26.7 16.6 18.8 9.8 15.0 25.9 6.2 26.8 20.6 24.7 6.3 10.7 7.3 34.2 22.1 19.2 12.6 5.8 10.6 24.6 9.4 20.0 19.0 37.1 20.9 37.7 21.4 18.6 24.0 7.2 16.6 11.3 5.0 32.5 25.2 21.9 408.0 160.0 9.7 1.3 34.6 34.7 0.5 314.5 280.2 450.9 278.2 8.5 185.5 0.2 124.7 501.2 235.3 33.3 0.4 211.8 384.8 0.7 0.3 0.0 100.4 6.3 125.0 0.3 0.3 26.4 3.8 266.7 409.5 254.8 169.8 0.1 15.8 0.5 284.6 0.5 0.2 0.4 4.1 1.0 76.3 0.2 165.3 0.3 202.3 0.2 0.1 0.1 81.5 0.6 1.8 57.4 0.9 7.2 351.8 317.8 214.6 307.7 540.8 0.5 0.9 1.0 211.5 0.5 241.8 1.5 0.3 0.2 0.1 0.4 0.2 0.1 0.3 0.1 6.0 0.1 0.3 0.3 0.3 11.1 0.2 25.7 0.4 0.3 17.5 22.6 19.7 17.7 16.6 18.8 26.8 20.6 22.1 20.9 24.0 21.9 13.5 9.6 3.6 35.9 1.9 41.7 88.3 10.3 3.4 0.5 2.3 14.2 8.6 1.5 4.4 5.5 0.0 4.2 0.8 0.1 0.0 6.9 8.7 6.0 45.8 17.7 0.0 0.0 0.8 0.2 2.1 147.2 1.5 5.4 0.0 17.3 11.0 1.2 28.8 1.7 1.1 0.1 2.0 187.5 185.5 5.5 61.5 61.4 26.6 30.9 3.1 26.8 0.0 11.1 0.5 14.5 0.1 79.7 0.8 123.4 0.3 0.1 2.8 1.2 210.4 38.1 171.1 1.9 2.0 1.2 29.1 11.5 3.6 2.5 0.1 28.0 AZGP1 "ZA2G, ZAG" ENSG00000160862 "Alpha-2-glycoprotein 1, zinc-binding" P25311 7 99966720-99976042 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 2809.6;salivary gland: 3847.3" "Cell type enhanced" "Detected in many" "Breast glandular cells: 1315.5;Breast myoepithelial cells: 704.8;Hepatocytes: 4270.8;Ionocytes: 901.3;Prostatic glandular cells: 1691.9;Urothelial cells: 674.2" "Group enriched" "Detected in many" 12 "breast cancer: 412.6;liver cancer: 273.6;prostate cancer: 469.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 56.6;OE19: 158.9;RPMI-8226: 130.4;T-47d: 41.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012582, HPA012876, CAB016087, CAB032276" Enhanced Approved Nucleoplasm,Vesicles "Secreted to blood" NA NA 55200000000 74000000000 "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 35: Glandular cells - Unknown function" Vesicles Nucleoplasm "CAB016087: AB_667849, CAB032276: AB_2062580, HPA012582: AB_1845226, HPA012876: " "unprognostic (8.14e-2)" "unprognostic (1.50e-1)" "unprognostic (3.41e-1)" "unprognostic (5.42e-3)" "unprognostic (4.98e-2)" "unprognostic (5.74e-3)" "prognostic favorable (2.90e-4)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (2.19e-1)" "unprognostic (2.35e-2)" "unprognostic (1.79e-1)" "prognostic favorable (1.53e-4)" "unprognostic (2.18e-1)" "unprognostic (2.08e-2)" "unprognostic (9.80e-2)" "unprognostic (3.51e-3)" 128.6 3.9 17.1 2.7 28.8 0.4 1061.4 23.1 18.8 3.4 16.0 6.7 30.9 1.5 2.5 22.0 3.0 38.7 114.7 14.9 22.2 326.8 2809.6 14.8 0.4 20.2 23.3 6.0 752.1 0.1 1.3 0.5 27.1 1051.4 4.2 3.6 3847.3 40.2 1.7 206.8 28.6 0.3 14.0 1.4 315.2 25.9 21.4 0.8 1.9 2.3 1.5 5.8 7.5 24.5 0.2 0.0 0.0 0.0 11.3 0.0 5.5 0.0 0.0 0.0 0.0 0.1 4.0 14.2 0.7 0.0 0.1 0.9 0.0 0.0 0.1 0.0 0.1 0.3 0.1 56.6 4.9 1.5 0.1 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.3 29.9 0.0 0.0 0.0 5.1 0.2 158.9 0.0 0.0 1.7 130.4 0.0 0.0 0.0 2.0 1.0 25.4 13.0 0.0 41.8 0.0 0.0 0.5 0.1 1.8 0.9 1.9 0.8 0.4 0.0 0.5 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 28.8 23.1 18.8 14.9 22.2 20.2 23.3 27.1 14.0 21.4 24.5 9.9 22.4 276.8 0.0 14.7 4.2 422.1 25.3 0.0 0.0 1315.5 704.8 115.9 451.8 63.0 5.5 2.1 0.0 10.4 5.5 46.9 11.7 1.9 1.4 1.2 14.2 12.4 85.5 0.1 254.2 0.0 7.7 94.8 5.5 3.8 1.2 65.3 4270.8 0.0 0.0 0.1 13.1 901.3 93.1 0.7 4.2 0.9 14.8 62.2 1.0 2.0 23.7 0.0 7.5 7.3 221.5 6.4 0.0 0.3 1691.9 15.3 596.1 6.3 0.3 0.0 0.0 11.9 7.4 0.4 9.9 9.7 0.0 12.3 0.1 12.6 674.2 AZIN1 "OAZI, OAZIN, ODC1L" ENSG00000155096 "Antizyme inhibitor 1" O14977 8 102826308-102893864 "Predicted intracellular proteins" "Polyamine biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 261.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027948 Approved Approved Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 41: Macrophages - Immune response" Vesicles "HPA027948: AB_10602391" "unprognostic (1.16e-2)" "unprognostic (4.81e-3)" "unprognostic (2.23e-1)" "unprognostic (1.41e-1)" "unprognostic (8.55e-2)" "unprognostic (3.41e-2)" "unprognostic (7.19e-2)" "unprognostic (1.51e-2)" "unprognostic (2.10e-1)" "unprognostic (2.24e-1)" "unprognostic (2.07e-3)" "unprognostic (4.33e-3)" "unprognostic (1.25e-2)" "unprognostic (1.08e-1)" "unprognostic (2.83e-1)" "unprognostic (3.08e-2)" "unprognostic (1.68e-1)" 61.7 48.1 45.7 48.1 50.3 141.1 57.8 44.8 51.2 55.3 43.5 49.1 66.6 44.4 30.3 52.7 64.0 43.6 51.5 51.9 50.5 39.4 78.0 40.1 58.1 48.1 48.2 38.7 136.6 38.3 31.6 82.8 48.1 52.5 53.6 57.8 47.7 49.5 41.9 32.7 80.8 44.5 53.8 35.9 52.2 35.7 46.7 58.6 67.5 30.9 60.6 62.3 27.3 60.0 320.4 81.7 129.0 92.6 122.7 83.3 77.6 145.4 168.5 103.5 106.8 87.1 217.5 148.0 111.0 121.9 64.3 119.5 113.8 114.5 165.8 244.7 57.4 147.4 30.1 72.3 156.0 81.0 120.7 58.9 136.1 72.5 182.4 92.2 72.8 86.0 112.6 124.0 165.2 92.6 201.8 59.3 144.9 239.3 123.0 87.3 136.5 84.2 108.2 146.7 208.2 327.3 49.1 100.0 144.3 209.9 131.7 84.7 85.9 83.2 83.9 135.7 118.6 122.3 104.2 207.4 98.3 120.1 117.0 73.3 57.7 68.0 31.2 64.1 36.7 43.7 40.8 29.9 55.9 27.5 33.1 32.1 68.5 40.1 64.5 44.3 50.0 65.7 45.7 50.3 44.8 51.2 51.9 50.5 48.1 48.2 48.1 53.8 46.7 60.0 56.3 60.9 27.7 30.0 59.6 93.8 121.1 52.8 93.4 31.5 64.0 39.8 46.3 28.6 52.8 42.3 37.5 148.7 54.0 48.4 52.8 39.6 62.6 95.1 37.9 34.9 84.9 62.7 35.9 50.5 55.0 55.5 59.1 85.4 68.5 31.9 33.5 65.0 54.7 23.5 31.9 77.3 63.1 72.8 127.2 107.9 49.7 86.0 64.0 23.4 53.0 50.4 32.0 30.2 23.7 66.6 44.0 32.4 97.6 106.7 114.6 52.6 167.6 42.3 19.7 36.0 57.1 34.5 30.7 90.8 82.3 261.9 71.6 26.2 66.0 117.0 AZU1 "AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC" ENSG00000172232 "Azurocidin 1" P20160 19 825097-832018 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Heparin-binding, Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 48 "bone marrow: 1578.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 4.5;Breast myoepithelial cells: 4.6;Endometrial ciliated cells: 8.9;Erythroid cells: 8.8;Respiratory ciliated cells: 4.5;Skeletal myocytes: 5.7;Spermatogonia: 6.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 9 "neutrophil: 3.3" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.3" "Cell line enriched" "Detected in some" 15 "THP-1: 659.5" "Not detected" "Not detected" "HPA055851, HPA075964" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 320000 "Cluster 1: Neutrophils - Mixed function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA055851: AB_2682943, HPA075964: " "unprognostic (1.12e-2)" "unprognostic (3.71e-2)" "unprognostic (4.44e-2)" "unprognostic (8.85e-3)" "unprognostic (1.62e-2)" "unprognostic (1.29e-1)" "unprognostic (1.39e-1)" "unprognostic (8.12e-2)" "unprognostic (3.32e-1)" "unprognostic (4.22e-3)" "unprognostic (2.58e-1)" "unprognostic (1.50e-1)" "unprognostic (1.01e-6)" "unprognostic (1.11e-2)" "unprognostic (1.10e-1)" "unprognostic (2.46e-2)" "unprognostic (3.04e-2)" 0.8 0.2 0.4 0.0 0.4 1578.1 1.5 0.2 0.9 0.2 0.2 0.2 0.0 0.5 0.0 0.1 1.4 0.0 2.0 0.4 0.3 0.4 2.8 15.9 0.6 0.3 0.3 0.2 0.2 0.0 0.9 0.9 0.4 0.4 0.0 0.0 2.6 0.0 0.5 0.6 0.2 0.0 0.2 33.1 0.2 2.4 0.4 3.1 0.5 0.0 0.0 0.3 0.2 0.3 1.1 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 2.3 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 44.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.4 0.6 659.5 0.0 0.0 0.1 0.0 0.8 0.0 0.1 0.6 0.0 34.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.3 0.0 0.1 0.0 0.0 0.1 0.4 0.4 0.2 0.9 0.4 0.3 0.3 0.3 0.4 0.2 0.4 0.3 3.5 0.0 0.0 0.0 0.6 0.0 0.1 1.2 0.0 0.0 4.5 4.6 0.7 0.0 0.5 0.0 0.0 0.2 2.8 0.6 0.0 0.1 0.0 8.9 1.2 1.0 0.0 8.8 0.8 0.0 0.3 0.8 0.0 2.3 0.0 0.1 0.0 0.4 3.2 0.0 1.4 0.4 0.0 3.7 0.4 0.7 0.0 3.2 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.2 0.2 0.0 4.5 0.0 0.0 5.7 1.2 0.1 6.4 0.9 0.1 0.0 1.0 0.0 0.6 0.0 B3GALNT1 "B3GALT3, beta3Gal-T3, galT3, GLOB, P1" ENSG00000169255 "Beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)" O75752 3 161083883-161105411 "Blood group antigen proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 53.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 56.3;Cardiomyocytes: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 8.8;NK-cell: 22.1" "Group enriched" "Detected in many" 7 "granulocytes: 8.8;NK-cells: 22.1" "Cell line enhanced" "Detected in many" "RT4: 128.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041204 Approved Vesicles NA NA 400000 "Cluster 48: NK-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 15: RT4 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA041204: AB_10795585" "unprognostic (3.85e-2)" "unprognostic (5.11e-3)" "unprognostic (3.02e-1)" "unprognostic (1.06e-2)" "unprognostic (7.83e-2)" "unprognostic (4.07e-2)" "unprognostic (9.26e-5)" "unprognostic (1.49e-2)" "unprognostic (1.12e-2)" "unprognostic (1.88e-2)" "unprognostic (3.44e-2)" "unprognostic (3.24e-1)" "unprognostic (2.09e-3)" "unprognostic (1.32e-1)" "unprognostic (4.90e-2)" "unprognostic (3.66e-2)" "unprognostic (3.19e-3)" 5.3 7.2 20.7 3.9 21.5 4.8 9.8 14.7 19.6 20.1 8.0 2.7 1.9 9.9 8.5 6.8 14.2 9.9 53.3 21.7 26.7 19.4 1.2 14.6 4.9 12.8 21.7 18.8 11.1 8.6 9.8 13.9 18.0 11.6 2.4 26.6 22.3 8.5 1.4 2.5 2.4 9.9 14.1 6.2 10.7 8.4 25.7 2.8 27.0 3.2 5.4 12.3 5.4 13.0 17.3 0.3 7.5 0.1 1.0 2.8 0.1 9.3 8.7 22.3 7.3 11.3 13.2 0.0 35.7 8.0 12.7 3.9 0.0 16.9 7.5 0.0 0.0 9.0 5.7 0.0 11.2 0.2 0.0 23.3 5.4 6.1 1.4 15.6 31.6 0.0 0.0 0.0 8.3 29.4 0.1 0.0 17.4 0.2 38.9 0.1 0.0 0.2 9.3 128.3 15.1 0.1 23.7 8.8 6.3 3.0 35.6 13.3 0.0 0.2 15.5 0.5 0.2 3.6 0.1 0.2 14.7 0.0 0.0 8.8 0.2 0.0 0.4 0.2 0.4 2.3 0.2 0.4 1.7 0.2 0.4 0.9 0.4 22.1 0.1 1.1 0.0 0.7 20.7 21.5 14.7 19.6 21.7 26.7 12.8 21.7 18.0 14.1 25.7 13.0 5.0 19.2 2.2 10.1 2.1 5.0 5.2 5.7 6.2 56.3 7.5 6.2 56.9 0.0 8.0 14.7 12.5 21.2 1.2 0.1 11.7 3.5 0.7 4.9 5.8 7.7 1.8 17.0 22.3 8.5 13.0 13.3 4.6 8.7 10.2 13.0 6.1 0.2 9.8 6.7 27.5 0.1 6.1 2.1 6.8 2.2 7.2 3.4 10.6 9.4 4.3 12.6 1.0 14.6 3.2 9.8 0.1 5.3 0.2 6.2 0.1 15.8 3.1 8.4 0.0 5.3 13.2 6.5 20.7 8.4 2.6 5.1 1.2 4.6 0.7 4.5 B3GAT1 "CD57, GlcAT-P, HNK-1, LEU7, NK-1" ENSG00000109956 "Beta-1,3-glucuronyltransferase 1" Q9P2W7 11 134378504-134412242 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 195.2" "Cell type enhanced" "Detected in some" "Astrocytes: 27.4;Bipolar cells: 37.0;Excitatory neurons: 37.2;Inhibitory neurons: 30.4;Muller glia cells: 116.2;Oligodendrocyte precursor cells: 33.2;Oligodendrocytes: 77.8" "Group enriched" "Detected in some" 11 "glioma: 10.8;prostate cancer: 3.5;thyroid cancer: 4.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.1" "Lineage enriched" "Detected in single" 12 "T-cells: 1.1" "Cell line enhanced" "Detected in some" "AF22: 23.1;HMC-1: 25.3;NTERA-2: 22.1;SH-SY5Y: 8.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002500, CAB010893, HPA069468, HPA074314" Enhanced Enhanced Vesicles "Secreted in brain" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" Vesicles "CAB002500: AB_563601, CAB010893: AB_1078474, HPA069468: AB_2686138, HPA074314: " "unprognostic (6.72e-2)" "unprognostic (3.97e-4)" "unprognostic (2.13e-2)" "unprognostic (1.40e-3)" "unprognostic (5.52e-2)" "unprognostic (2.60e-3)" "unprognostic (6.30e-2)" "unprognostic (1.96e-2)" "unprognostic (8.74e-2)" "unprognostic (2.72e-1)" "unprognostic (1.57e-3)" "unprognostic (1.58e-1)" "unprognostic (9.34e-3)" "unprognostic (3.87e-3)" "unprognostic (2.42e-1)" "unprognostic (4.07e-2)" "unprognostic (2.26e-2)" 0.2 4.2 146.6 0.4 135.6 1.0 3.9 114.3 195.2 0.4 32.5 0.9 0.5 1.4 0.2 0.2 0.4 0.3 0.3 191.8 85.5 1.8 5.8 0.6 2.1 133.6 145.2 0.2 0.4 0.0 4.5 0.1 118.9 2.8 0.1 23.8 1.2 0.4 0.1 0.5 0.6 0.1 115.0 1.4 34.9 0.9 133.6 0.4 6.2 0.2 0.4 0.7 0.3 176.0 0.0 0.0 23.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.7 3.9 0.0 0.9 1.2 1.6 0.0 0.0 0.0 0.7 0.1 0.2 0.0 0.1 0.1 25.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.1 0.0 0.1 22.1 1.1 0.0 0.4 0.0 1.7 0.0 0.1 3.1 8.4 0.0 0.0 0.0 1.5 0.1 0.0 0.1 0.0 2.3 0.1 0.0 0.1 0.0 0.1 0.2 0.1 5.8 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 146.6 135.6 114.3 195.2 191.8 85.5 133.6 145.2 118.9 115.0 133.6 176.0 0.1 0.0 0.0 27.4 0.1 0.0 0.0 0.0 0.0 37.0 1.2 0.8 1.1 2.8 0.0 0.0 4.2 0.0 14.4 0.1 0.0 0.0 1.8 0.1 0.1 0.4 1.8 0.4 37.2 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.4 4.7 0.1 23.5 30.4 0.0 0.0 0.3 0.0 3.9 0.0 0.2 0.0 3.7 0.0 116.2 15.5 33.2 77.8 0.0 0.0 0.4 7.5 0.9 0.0 1.9 0.0 8.6 0.0 0.1 0.2 0.2 0.8 0.0 0.0 0.1 3.8 0.0 0.0 0.3 B3GNT2 "B3GN-T1, B3GN-T2, B3GNT-2, B3GNT1, BETA3GNT" ENSG00000170340 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2" Q9NY97 2 62196115-62224731 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 115.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005997 Approved Approved Vesicles NA NA 99000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 14: REH - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA005997: AB_1845234" "unprognostic (1.38e-1)" "unprognostic (1.13e-1)" "unprognostic (1.28e-1)" "unprognostic (2.64e-2)" "unprognostic (1.23e-2)" "unprognostic (1.67e-1)" "unprognostic (1.51e-1)" "unprognostic (1.55e-2)" "unprognostic (2.13e-2)" "unprognostic (3.76e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (3.63e-1)" "unprognostic (1.11e-2)" "unprognostic (9.55e-2)" "unprognostic (3.05e-2)" "unprognostic (3.18e-1)" "unprognostic (1.25e-1)" 17.3 20.8 6.6 13.3 13.6 72.7 26.1 5.9 9.8 25.9 9.0 19.4 27.7 24.6 6.2 25.1 12.7 27.4 19.0 6.8 8.6 33.4 21.8 34.2 24.1 6.9 8.3 5.9 39.7 7.6 13.2 30.6 9.7 10.8 24.3 5.2 15.5 8.2 3.2 11.0 14.4 24.1 6.1 14.9 18.2 7.6 8.5 25.5 19.5 9.0 18.3 20.1 12.8 6.7 20.7 14.0 20.9 9.3 22.5 10.0 60.0 19.8 21.8 15.4 20.5 29.2 32.5 22.3 17.8 18.5 21.6 19.4 13.3 16.6 26.5 46.8 10.8 55.1 6.4 17.2 16.8 33.2 23.8 12.3 30.7 29.6 10.5 11.0 23.4 15.3 30.4 13.7 18.9 15.7 63.7 49.6 20.0 37.4 5.8 115.0 14.4 12.3 29.2 20.1 20.1 14.9 14.1 29.9 23.5 33.4 8.6 38.7 26.7 18.6 16.4 31.7 19.9 38.2 14.4 96.2 14.6 56.5 18.4 14.9 9.0 56.2 20.0 8.6 28.0 14.8 14.7 34.6 10.6 16.6 17.3 26.0 21.3 41.0 11.7 13.3 26.2 17.6 6.6 13.6 5.9 9.8 6.8 8.6 6.9 8.3 9.7 6.1 8.5 6.7 40.3 64.1 9.8 2.0 31.4 71.5 30.9 20.8 92.2 15.6 40.0 20.7 9.2 18.6 21.9 18.4 0.0 40.9 43.8 42.7 23.5 24.0 0.1 51.1 30.3 31.8 9.5 61.6 11.2 57.2 38.3 19.5 36.7 97.3 3.8 9.7 37.5 21.3 60.4 0.0 3.4 22.7 87.5 20.5 58.5 0.7 2.5 34.4 35.6 14.0 19.7 8.6 18.6 2.5 7.2 36.3 24.8 2.2 25.8 25.5 14.2 19.0 19.1 2.1 65.7 8.1 68.2 0.3 1.6 77.4 64.8 65.3 45.9 10.6 13.9 41.1 B3GNTL1 B3GNT8 ENSG00000175711 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1" Q67FW5 17 82942155-83051810 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 19.9;Respiratory ciliated cells: 20.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 25.1;HL-60: 27.0;THP-1: 25.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023585, HPA024547" Supported Approved "Nucleoli,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoli, Nucleoli fibrillar center" Vesicles "HPA023585: AB_2061075, HPA024547: AB_1845240" "unprognostic (1.51e-2)" "unprognostic (9.84e-2)" "unprognostic (4.11e-1)" "unprognostic (2.34e-1)" "unprognostic (1.38e-1)" "unprognostic (8.11e-2)" "unprognostic (2.61e-7)" "unprognostic (9.95e-2)" "unprognostic (2.62e-1)" "unprognostic (1.62e-1)" "unprognostic (8.74e-2)" "unprognostic (2.80e-2)" "unprognostic (4.17e-9)" "unprognostic (2.02e-1)" "unprognostic (1.47e-1)" "unprognostic (1.88e-1)" "unprognostic (3.39e-3)" 2.9 2.8 1.8 2.9 2.1 7.8 2.4 1.4 2.3 3.5 3.9 2.0 1.7 3.7 1.2 2.4 3.7 1.3 3.0 1.9 1.4 1.9 2.4 3.0 2.3 1.3 1.5 3.9 2.3 0.8 2.6 1.4 1.6 2.6 0.9 0.5 2.1 1.5 3.8 2.3 2.1 1.8 1.3 4.2 2.0 3.0 2.1 2.3 2.4 1.4 1.1 3.1 2.5 1.6 11.9 7.8 0.2 3.7 2.1 6.6 4.7 4.2 3.7 4.8 3.7 4.7 25.1 5.8 8.1 5.2 11.7 2.2 1.9 0.0 4.1 8.9 5.1 12.2 12.6 16.0 7.5 27.0 0.5 2.4 2.1 2.9 4.8 2.4 5.9 8.9 5.4 5.5 3.9 2.7 7.6 10.3 1.8 8.1 5.6 9.8 0.9 0.4 2.7 2.5 2.4 0.9 3.6 2.7 3.7 3.4 0.0 25.5 9.7 9.2 6.2 1.4 7.6 1.1 2.9 4.4 10.3 3.6 1.3 3.0 6.0 1.0 2.8 5.9 4.4 3.0 4.4 3.3 10.4 5.5 3.9 4.7 19.0 3.2 3.2 4.1 13.5 4.0 1.8 2.1 1.4 2.3 1.9 1.4 1.3 1.5 1.6 1.3 2.1 1.6 2.6 3.2 4.5 4.6 2.9 1.0 2.0 4.4 3.4 3.5 3.0 3.0 2.8 1.5 6.4 5.5 4.2 5.7 3.6 1.3 1.9 1.9 15.3 6.8 4.2 2.3 1.2 7.6 11.3 1.0 3.1 4.0 3.1 1.9 7.0 7.6 1.4 2.0 7.7 3.3 9.2 1.5 6.1 7.3 2.8 19.9 3.1 8.9 1.8 6.5 5.5 1.3 8.2 5.0 4.7 2.1 2.7 4.9 5.2 2.8 0.2 2.4 20.7 3.5 0.0 2.5 2.3 0.9 5.0 5.6 1.7 1.9 6.8 4.8 3.5 2.1 B4GALNT3 "B4GalNac-T3, FLJ16224, FLJ40362" ENSG00000139044 "Beta-1,4-N-acetyl-galactosaminyltransferase 3" Q6L9W6 12 459939-563509 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 61.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 81.1;Gastric mucus-secreting cells: 128.0;Glandular and luminal cells: 47.4;Late spermatids: 89.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 33.5;HDLM-2: 13.2;HEK 293: 12.5;NTERA-2: 14.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA011404 Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 28: BEWO - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" Vesicles "HPA011404: AB_1845242" "unprognostic (2.38e-2)" "unprognostic (9.59e-3)" "unprognostic (1.38e-1)" "prognostic favorable (1.69e-10)" "unprognostic (4.22e-2)" "unprognostic (4.63e-2)" "unprognostic (1.46e-2)" "unprognostic (9.53e-3)" "unprognostic (3.29e-1)" "unprognostic (1.61e-1)" "unprognostic (1.23e-1)" "unprognostic (1.02e-1)" "unprognostic (5.46e-2)" "unprognostic (9.99e-3)" "unprognostic (2.82e-1)" "unprognostic (2.48e-2)" "unprognostic (2.98e-1)" 0.2 7.0 0.5 3.2 0.7 2.1 1.3 0.0 1.0 7.4 1.0 18.4 1.0 6.2 2.7 7.5 3.7 2.2 23.9 0.5 0.0 4.6 0.1 5.2 0.1 0.0 0.0 0.4 2.6 16.9 9.3 0.1 0.0 2.0 12.5 0.1 4.8 0.7 1.5 14.8 2.0 2.2 0.0 0.3 61.0 8.0 0.0 2.3 2.3 0.1 0.7 1.4 5.6 0.7 0.0 0.0 0.3 1.2 0.0 0.0 33.5 0.0 0.0 0.0 0.0 8.0 6.6 0.0 0.9 0.0 0.7 3.6 8.0 1.1 0.1 13.2 12.5 0.0 0.0 1.8 0.0 0.1 5.3 0.0 5.3 0.0 0.0 0.1 0.0 0.9 0.1 0.0 0.0 0.4 0.0 0.1 14.8 10.5 0.6 0.5 5.0 0.0 7.1 6.8 3.8 2.7 0.8 0.3 1.0 4.9 0.8 2.9 0.0 0.0 2.7 0.2 0.9 0.0 0.0 0.0 0.0 9.2 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.0 1.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 7.0 1.3 0.3 7.5 6.0 3.4 0.0 0.6 2.9 0.6 15.1 1.5 6.2 9.2 0.0 0.0 0.6 81.1 0.0 12.0 26.3 20.4 4.8 0.6 10.3 0.0 32.6 4.8 0.1 1.6 128.0 47.4 0.0 0.1 0.0 0.1 0.7 0.0 5.2 18.6 2.0 0.0 1.1 89.2 0.0 0.5 0.0 2.8 0.6 0.0 0.0 1.0 3.6 16.6 33.4 0.0 0.2 12.7 1.9 0.2 9.1 0.2 0.0 0.2 0.8 2.8 1.3 0.9 17.3 0.0 1.5 1.9 26.1 14.4 B4GALNT4 "FLJ25045, NGalNAc-T1" ENSG00000182272 "Beta-1,4-N-acetyl-galactosaminyltransferase 4" Q76KP1 11 369499-382117 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.3;ovary: 27.8" "Cell type enhanced" "Detected in many" "Astrocytes: 133.2;Bipolar cells: 23.8;Excitatory neurons: 31.2;Horizontal cells: 33.7;Inhibitory neurons: 32.3;Muller glia cells: 45.6;Oligodendrocyte precursor cells: 28.1;Oligodendrocytes: 32.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 35.4;NTERA-2: 32.0;SCLC-21H: 39.5;SH-SY5Y: 47.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043276, HPA053126" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol "Intracellular and membrane" NA No "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Cytosol" Vesicles "HPA043276: , HPA053126: AB_2682049" "unprognostic (6.11e-2)" "unprognostic (7.82e-2)" "unprognostic (1.79e-1)" "unprognostic (6.92e-3)" "unprognostic (5.36e-2)" "unprognostic (1.57e-1)" "unprognostic (1.45e-1)" "unprognostic (2.72e-2)" "unprognostic (1.33e-1)" "unprognostic (1.53e-1)" "unprognostic (1.69e-3)" "unprognostic (4.99e-3)" "unprognostic (1.52e-10)" "unprognostic (9.01e-2)" "unprognostic (2.56e-1)" "unprognostic (2.92e-4)" "unprognostic (1.25e-1)" 0.9 0.6 23.1 0.9 17.2 0.0 3.3 5.1 33.3 17.2 0.0 5.9 0.6 14.1 0.6 2.3 11.9 0.5 1.6 23.8 12.9 1.0 0.3 0.5 0.3 19.3 20.7 27.8 1.1 2.6 17.9 0.0 14.9 6.3 0.2 5.3 2.0 1.2 0.0 2.1 2.9 1.0 8.4 0.3 2.1 1.5 15.1 0.3 0.5 0.0 0.3 1.8 6.3 13.4 0.0 4.8 35.4 20.4 0.0 0.1 8.4 6.5 1.7 2.9 0.8 3.7 0.0 0.0 4.8 0.7 5.6 1.4 4.8 8.5 0.8 0.0 12.3 0.0 13.4 11.4 0.4 0.0 8.7 0.6 5.0 0.2 3.8 12.7 0.4 1.9 11.5 0.0 0.0 10.8 0.4 0.0 32.0 0.6 14.0 0.0 0.0 4.9 0.4 0.0 39.5 47.6 2.4 1.7 0.5 3.7 14.0 0.0 9.0 2.0 11.1 3.5 0.4 0.1 1.7 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.1 17.2 5.1 33.3 23.8 12.9 19.3 20.7 14.9 8.4 15.1 13.4 0.1 0.0 0.0 133.2 0.2 0.8 1.5 1.4 0.6 23.8 6.5 8.9 12.5 0.0 0.1 1.8 4.2 0.1 0.3 0.1 0.0 1.3 0.0 0.6 7.1 0.6 1.8 0.0 31.2 0.0 0.0 2.4 0.0 1.1 0.0 6.9 0.0 0.0 0.2 33.7 32.3 0.1 2.0 0.0 0.0 0.0 3.1 0.1 3.6 2.8 0.2 45.6 0.0 28.1 32.5 0.2 0.0 1.2 0.0 2.6 0.0 0.0 0.1 8.6 0.0 0.0 3.3 0.1 0.2 0.1 0.3 0.3 0.1 0.6 0.5 0.4 B4GALT2 beta4Gal-T2 ENSG00000117411 "Beta-1,4-galactosyltransferase 2" O60909 1 43978943-43991170 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007620, HPA047739" Supported Supported "Golgi apparatus,Vesicles" NA NA 3100000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus, Vesicles" "HPA007620: AB_2667879, HPA047739: AB_2680141" "unprognostic (1.11e-1)" "unprognostic (1.82e-1)" "unprognostic (1.15e-1)" "unprognostic (7.59e-2)" "unprognostic (1.19e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (2.96e-5)" "unprognostic (1.12e-2)" "unprognostic (1.45e-1)" "unprognostic (2.08e-2)" "unprognostic (4.23e-3)" "unprognostic (7.58e-2)" "prognostic unfavorable (3.62e-5)" "unprognostic (6.54e-2)" "unprognostic (1.52e-1)" "unprognostic (7.66e-2)" "unprognostic (3.12e-3)" 29.0 19.0 61.4 13.0 55.0 6.6 24.6 48.0 70.1 28.4 44.0 43.7 12.5 31.0 9.6 32.4 20.0 14.9 40.8 58.4 51.6 24.6 38.8 19.6 5.9 53.6 53.6 19.6 51.5 14.2 24.7 10.1 53.0 31.2 10.2 8.9 27.3 23.8 61.0 32.8 15.2 26.3 52.6 12.0 22.4 22.6 55.2 3.1 14.3 33.2 6.8 37.0 26.8 52.6 61.6 38.4 45.3 76.0 51.3 54.5 37.8 54.2 55.9 54.8 50.9 30.4 51.4 38.4 31.6 112.3 52.5 39.9 36.8 72.8 14.0 39.6 80.2 23.2 37.8 66.9 43.2 20.6 0.8 47.0 79.1 39.3 71.4 55.3 65.5 15.9 51.7 25.3 46.7 45.3 15.3 18.6 65.6 35.7 56.7 44.3 48.2 62.7 33.9 29.3 72.7 58.5 31.1 89.4 38.5 16.9 38.6 17.5 39.3 90.8 102.4 63.8 78.5 7.6 17.8 15.9 40.4 16.9 64.6 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.1 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 61.4 55.0 48.0 70.1 58.4 51.6 53.6 53.6 53.0 52.6 55.2 52.6 9.7 0.0 8.8 7.5 2.2 7.8 10.3 10.8 1.8 13.3 15.0 18.9 14.0 7.2 7.4 14.7 4.2 2.0 1.2 10.2 1.9 13.3 16.4 6.2 16.2 10.4 16.3 1.3 8.0 20.6 8.0 15.2 13.7 8.7 0.0 23.8 6.1 18.7 2.3 18.5 5.6 22.6 2.0 1.0 3.3 6.7 16.4 1.5 3.6 1.0 1.6 15.0 0.0 5.0 9.8 27.3 6.1 12.4 5.0 25.9 6.4 8.8 4.4 12.2 6.6 9.8 14.3 6.2 15.6 7.6 12.6 0.5 1.7 21.1 15.3 16.1 B4GALT5 beta4GalT-V ENSG00000158470 "Beta-1,4-galactosyltransferase 5" O43286 20 49632945-49713878 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Urothelial cells: 128.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 6.6" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077777 Approved Vesicles "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Vesicles "HPA077777: " "unprognostic (7.98e-2)" "unprognostic (5.27e-2)" "unprognostic (2.62e-1)" "unprognostic (1.88e-2)" "unprognostic (2.76e-1)" "unprognostic (1.61e-2)" "prognostic unfavorable (2.69e-5)" "unprognostic (1.73e-1)" "unprognostic (1.50e-1)" "unprognostic (1.39e-2)" "prognostic unfavorable (1.87e-5)" "unprognostic (1.04e-1)" "unprognostic (1.50e-1)" "unprognostic (3.30e-2)" "unprognostic (5.41e-1)" "unprognostic (2.07e-1)" "unprognostic (2.69e-2)" 28.7 47.8 14.7 21.7 14.5 93.7 18.6 14.6 16.1 21.2 6.5 24.9 25.3 23.5 8.6 37.3 18.5 31.5 20.5 15.5 18.1 22.8 25.8 27.3 9.6 14.7 19.2 19.0 12.6 11.3 12.6 27.2 15.4 17.1 23.7 7.7 19.0 21.9 67.1 7.9 21.3 37.6 14.6 27.6 25.8 22.3 19.0 8.1 11.5 24.3 11.5 51.4 17.2 12.0 48.8 55.0 71.4 30.4 72.8 49.3 62.4 23.5 43.7 104.8 50.0 71.1 59.0 14.8 98.0 39.0 99.1 75.4 45.5 35.0 61.3 45.6 12.5 39.4 28.8 42.9 22.9 51.6 73.7 74.3 32.2 45.5 21.8 96.5 64.8 25.9 64.5 8.9 30.8 24.1 3.1 47.3 37.4 47.8 35.3 26.6 61.9 21.4 50.6 34.0 84.9 43.0 83.6 105.3 47.8 52.5 24.1 70.0 50.1 62.7 50.5 33.6 49.8 10.9 10.0 35.2 32.6 48.5 40.7 1.4 1.0 2.6 1.4 1.0 1.5 0.2 0.6 1.3 0.7 0.3 0.1 0.9 6.6 1.2 1.1 0.6 0.8 0.4 14.7 14.5 14.6 16.1 15.5 18.1 14.7 19.2 15.4 14.6 19.0 12.0 39.5 16.0 43.1 36.2 5.8 18.9 27.3 39.7 7.4 8.3 17.3 18.2 18.3 42.9 84.5 36.8 10.4 23.4 21.3 61.3 1.9 35.3 5.2 59.1 28.4 42.7 34.3 33.2 52.1 19.7 27.7 27.3 17.9 100.8 83.2 36.2 58.5 22.7 24.5 11.8 59.5 21.3 40.7 28.2 81.5 6.8 19.9 45.0 21.4 30.9 21.4 5.6 20.6 25.6 42.5 39.7 34.1 32.7 7.3 66.8 13.4 33.5 57.0 4.9 26.3 29.9 25.9 10.3 16.0 27.5 17.5 5.6 17.4 33.1 20.0 128.9 BAAT BAT ENSG00000136881 "Bile acid-CoA:amino acid N-acyltransferase" Q14032 9 101354182-101385400 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Serine esterase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 41 "liver: 721.0" "Cell type enriched" "Detected in some" 10 "Hepatocytes: 996.7" "Cancer enriched" "Detected in many" 42 "liver cancer: 181.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 3.4;CACO-2: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021251, HPA021330" Enhanced Uncertain Vesicles NA NA 520000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA021251: AB_1845247, HPA021330: AB_2670674" "unprognostic (2.53e-2)" "unprognostic (1.81e-1)" "unprognostic (9.97e-2)" "unprognostic (9.33e-2)" "unprognostic (7.75e-3)" "unprognostic (4.68e-2)" "prognostic favorable (4.97e-4)" "unprognostic (2.14e-2)" "unprognostic (6.19e-2)" "unprognostic (4.43e-4)" "unprognostic (3.65e-1)" "unprognostic (2.15e-1)" "prognostic unfavorable (4.24e-7)" "unprognostic (1.74e-1)" "unprognostic (2.12e-1)" "unprognostic (2.17e-2)" "unprognostic (1.75e-1)" 0.1 0.0 0.5 0.0 0.5 1.2 0.0 0.5 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 17.4 0.1 0.5 0.4 0.3 721.0 0.4 0.0 0.4 0.3 0.0 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.8 0.0 3.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.1 0.1 0.1 0.4 0.8 0.2 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.5 1.0 0.5 0.4 0.4 0.3 0.5 0.1 0.3 0.8 0.3 0.0 0.0 0.7 2.4 0.0 0.1 0.0 0.0 1.1 0.3 0.1 0.7 91.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.1 0.0 0.1 0.7 0.0 16.0 9.7 0.2 0.0 0.1 0.0 0.1 0.0 0.0 12.1 996.7 0.0 0.0 7.2 0.0 0.0 18.2 0.0 0.0 0.0 0.1 0.0 1.9 0.0 0.1 0.0 3.0 0.9 1.8 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.2 0.0 0.5 0.1 0.3 0.2 0.0 0.0 0.0 1.0 0.1 0.4 0.0 BAG5 ENSG00000166170 "BAG cochaperone 5" Q9UL15 14 103556545-103562657 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 127.7" "Group enriched" "Detected in all" 13 "Early spermatids: 1734.2;Late spermatids: 1796.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016429 Enhanced Approved Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 83: Testis - Spermatogenesis" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA016429: AB_1845261" "unprognostic (3.02e-2)" "unprognostic (2.98e-2)" "unprognostic (1.05e-2)" "unprognostic (6.26e-2)" "unprognostic (2.54e-1)" "unprognostic (5.22e-2)" "unprognostic (1.99e-3)" "unprognostic (2.78e-1)" "unprognostic (1.04e-1)" "unprognostic (4.77e-3)" "unprognostic (2.34e-1)" "unprognostic (3.80e-2)" "prognostic favorable (1.58e-8)" "unprognostic (2.51e-1)" "unprognostic (1.52e-1)" "unprognostic (3.69e-2)" "unprognostic (2.53e-1)" 24.6 11.4 12.7 15.1 13.0 27.8 18.7 15.9 16.7 14.7 15.6 14.8 12.3 16.1 12.6 21.8 16.0 12.9 13.3 13.5 13.2 15.9 11.9 15.5 17.1 12.6 12.4 12.1 12.2 14.0 10.8 14.4 12.8 14.0 14.6 18.4 16.5 14.2 13.1 19.3 12.1 15.1 12.4 18.3 14.9 127.7 12.2 14.9 23.7 13.5 19.1 15.3 12.6 14.3 26.2 22.1 30.0 27.1 27.5 26.5 33.1 26.0 22.6 22.6 19.9 18.0 32.7 47.3 24.5 30.2 20.6 38.4 24.2 34.7 35.6 19.9 15.8 31.3 25.3 16.2 17.4 42.7 31.3 19.3 43.7 23.2 29.3 20.7 24.0 34.4 25.2 34.8 31.2 35.1 37.4 19.9 17.8 43.8 27.4 40.1 34.4 21.6 37.3 58.3 33.0 22.3 34.9 30.3 23.6 20.1 38.9 21.8 28.4 24.4 19.9 37.9 31.2 21.4 34.4 52.7 27.5 22.9 30.9 28.7 13.4 11.9 9.3 14.8 11.9 6.8 11.0 9.0 14.1 7.8 12.8 11.1 9.0 13.0 21.4 5.9 10.6 12.7 12.7 13.0 15.9 16.7 13.5 13.2 12.6 12.4 12.8 12.4 12.2 14.3 51.5 44.8 24.3 10.4 29.4 69.0 44.8 33.3 47.8 37.9 32.9 28.8 21.8 17.2 44.5 35.0 27.1 25.4 40.0 26.5 66.5 24.7 1734.2 78.6 43.7 41.2 31.7 29.5 18.9 19.1 17.7 31.7 26.0 89.5 32.3 19.3 52.5 25.6 22.1 75.7 14.7 25.0 32.6 29.2 26.4 1796.9 49.7 24.4 32.0 11.2 23.6 49.6 36.0 9.0 20.3 27.1 15.2 67.0 18.5 45.2 18.4 31.7 43.3 36.2 32.9 30.3 27.0 129.7 40.4 60.5 89.8 40.8 33.3 33.1 24.3 62.1 BAMBI NMA ENSG00000095739 "BMP and activin membrane bound inhibitor" Q13145 10 28677510-28682932 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 81.6" "Cell type enhanced" "Detected in many" "Breast glandular cells: 174.7;Breast myoepithelial cells: 163.2;Granulosa cells: 334.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 166.7;SK-MEL-30: 199.0;SuSa: 357.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010819, HPA010866" Approved Approved "Nucleoli fibrillar center,Vesicles,Lipid droplets" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Nucleoli fibrillar center, Lipid droplets" "HPA010819: AB_2668371, HPA010866: AB_10601686" "unprognostic (7.02e-3)" "unprognostic (4.52e-2)" "unprognostic (1.28e-2)" "unprognostic (3.17e-3)" "unprognostic (1.25e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (9.42e-6)" "unprognostic (1.09e-1)" "unprognostic (6.45e-3)" "unprognostic (1.05e-1)" "unprognostic (2.03e-3)" "unprognostic (9.29e-2)" "prognostic favorable (5.25e-4)" "unprognostic (1.01e-1)" "unprognostic (3.24e-1)" "unprognostic (2.38e-2)" "unprognostic (2.10e-2)" 4.4 44.1 13.8 2.3 16.3 6.0 23.7 18.4 17.6 5.7 20.7 3.8 1.6 17.9 2.9 2.1 6.3 5.4 43.5 13.6 15.9 19.9 23.9 12.0 2.0 19.9 16.9 81.6 6.9 8.2 8.5 39.3 21.1 7.4 4.7 13.4 6.4 16.7 1.8 5.4 2.1 12.2 16.6 18.0 3.8 8.7 14.8 0.4 1.2 1.9 1.4 30.0 5.4 22.7 1.0 41.0 4.2 2.2 4.8 0.1 24.5 9.7 3.5 15.4 10.0 166.7 17.3 0.5 5.7 7.4 8.8 12.2 10.2 1.6 7.2 10.1 21.0 39.5 6.2 63.7 5.9 2.4 51.5 3.7 2.3 10.4 1.6 96.7 2.4 2.1 22.1 18.7 3.1 70.1 0.2 3.3 71.6 34.5 9.9 0.3 7.8 3.6 12.9 40.4 6.8 5.2 13.2 78.5 199.0 357.8 23.2 3.0 0.3 10.4 7.3 17.0 4.7 0.5 15.0 0.0 1.0 8.9 67.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 16.3 18.4 17.6 13.6 15.9 19.9 16.9 21.1 16.6 14.8 22.7 6.6 9.6 5.9 15.0 5.7 4.0 7.6 0.6 13.1 14.3 174.7 163.2 34.9 58.6 3.5 11.0 4.2 12.0 9.3 33.8 1.9 20.8 0.1 14.3 15.3 7.3 26.8 0.0 0.5 0.2 22.2 46.1 58.6 21.1 1.3 334.8 14.6 16.0 6.7 6.7 0.2 3.8 0.0 1.6 4.2 1.2 3.4 5.4 16.0 15.9 0.7 50.2 0.0 46.3 21.2 12.1 34.6 2.2 4.3 10.8 1.1 16.1 1.4 5.9 0.0 4.2 42.7 1.9 15.5 13.5 1.3 8.5 7.8 6.2 3.8 14.1 BARX1 ENSG00000131668 "BARX homeobox 1" Q9HBU1 9 93951627-93955355 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "stomach 1: 166.5" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.0;Early spermatids: 2.6;Fibroblasts: 2.9;Smooth muscle cells: 1.2" "Cancer enhanced" "Detected in many" "stomach cancer: 19.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AN3-CA: 29.5;HMC-1: 69.8;NTERA-2: 20.7;THP-1: 28.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA055858 Approved Nucleoplasm,Vesicles NA NA "Cluster 4: Stomach - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm Vesicles "HPA055858: AB_2682947" "unprognostic (6.19e-4)" "unprognostic (4.81e-2)" "unprognostic (1.58e-2)" "prognostic unfavorable (8.16e-6)" "unprognostic (4.96e-3)" "prognostic unfavorable (1.02e-4)" "unprognostic (1.46e-2)" "unprognostic (5.20e-3)" "unprognostic (1.23e-2)" "unprognostic (8.75e-2)" "unprognostic (1.02e-1)" "unprognostic (3.33e-1)" "unprognostic (9.68e-13)" "unprognostic (7.02e-2)" "unprognostic (1.59e-1)" "unprognostic (2.60e-1)" "unprognostic (2.16e-2)" 17.1 0.0 0.4 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 2.9 0.0 0.3 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.6 15.1 1.5 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 166.5 3.9 0.0 0.0 1.0 0.5 0.4 0.0 0.0 0.0 0.0 2.0 0.0 29.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 5.6 0.0 4.3 0.1 0.2 0.0 0.0 0.0 0.8 0.0 0.6 0.0 0.0 0.0 69.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.4 20.7 0.0 0.0 2.1 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.3 5.8 0.0 28.6 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 2.9 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 BBOX1 "BBH, BBOX, G-BBH, gamma-BBH" ENSG00000129151 "Gamma-butyrobetaine hydroxylase 1" O75936 11 27040725-27127809 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carnitine biosynthesis" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 467.9;liver: 131.9" "Cell type enriched" "Detected in many" 7 "Proximal tubular cells: 1623.0" "Group enriched" "Detected in many" 6 "glioma: 23.7;renal cancer: 59.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "hTCEpi: 13.7;RPTEC TERT1: 7.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA007600, HPA027823" Enhanced Approved Uncertain "Vesicles,Actin filaments" NA NA 35000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "Actin filaments" "HPA007600: AB_1845284, HPA027823: AB_10602394" "unprognostic (9.96e-3)" "unprognostic (1.80e-2)" "unprognostic (8.17e-2)" "prognostic unfavorable (6.65e-4)" "unprognostic (7.03e-2)" "unprognostic (6.66e-2)" "unprognostic (7.05e-3)" "unprognostic (1.13e-2)" "unprognostic (3.03e-1)" "unprognostic (6.89e-2)" "unprognostic (2.03e-2)" "unprognostic (1.60e-1)" "prognostic favorable (1.45e-5)" "unprognostic (1.71e-2)" "unprognostic (2.70e-1)" "unprognostic (3.22e-1)" "unprognostic (1.73e-3)" 1.4 0.0 24.3 0.0 23.4 0.0 25.1 28.8 34.0 5.1 17.3 0.2 0.0 0.1 8.1 17.5 9.0 9.6 0.0 22.8 25.6 467.9 131.9 0.3 0.1 27.2 33.1 0.0 0.8 0.0 6.9 0.3 35.0 0.5 0.0 0.4 6.1 4.1 0.9 51.8 0.0 0.0 28.8 0.0 0.2 0.1 25.2 1.1 9.6 0.0 0.6 0.1 11.3 27.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.9 13.7 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.2 2.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.3 23.4 28.8 34.0 22.8 25.6 27.2 33.1 35.0 28.8 25.2 27.0 0.1 0.0 0.6 66.3 5.3 8.2 9.0 80.9 0.6 0.0 16.3 11.0 0.0 15.7 18.1 46.0 0.0 0.3 0.2 0.0 223.0 0.7 1.1 10.3 0.1 0.3 0.0 0.0 1.1 0.0 0.0 0.4 0.0 0.9 0.0 0.1 0.4 27.9 0.0 0.0 0.8 0.0 12.2 0.6 1.1 1.1 0.0 7.1 1.8 4.7 0.0 13.8 0.0 2.0 0.3 0.1 0.0 0.4 0.0 0.2 0.0 1623.0 9.4 0.4 0.0 0.0 1.4 0.0 0.6 16.9 35.8 0.3 5.0 0.0 0.0 2.6 BCAS1 "AIBC1, NABC1, PMES-2" ENSG00000064787 "Brain enriched myelin associated protein 1" O75363 20 53936777-54070594 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 890.2;choroid plexus: 301.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 182.6;Gastric mucus-secreting cells: 202.9;Intestinal goblet cells: 371.4;Oligodendrocyte precursor cells: 538.8;Oligodendrocytes: 718.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "MCF7: 44.2;OE19: 90.0;RT4: 179.5;SK-BR-3: 368.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033558, HPA051816, HPA054745" Enhanced Approved Vesicles NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 70: Brain - Nervous system development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" Vesicles "CAB033558: AB_2274632, HPA051816: AB_2681623, HPA054745: AB_2682590" "unprognostic (6.41e-2)" "unprognostic (1.01e-2)" "unprognostic (6.20e-2)" "unprognostic (7.23e-2)" "unprognostic (1.05e-1)" "unprognostic (2.43e-2)" "unprognostic (5.54e-2)" "unprognostic (1.86e-1)" "unprognostic (3.80e-1)" "unprognostic (1.19e-1)" "unprognostic (5.25e-2)" "unprognostic (2.91e-2)" "unprognostic (4.70e-3)" "unprognostic (3.95e-1)" "unprognostic (1.77e-1)" "unprognostic (1.75e-1)" "unprognostic (7.77e-3)" 1.2 0.2 506.5 6.4 627.9 0.1 3.4 551.3 890.2 7.3 301.2 69.5 19.0 1.3 2.2 7.2 1.5 8.6 0.4 421.4 525.8 3.3 0.4 2.9 0.6 749.3 660.7 0.4 0.9 0.0 1.0 0.1 649.9 33.4 74.3 0.2 22.3 0.3 0.5 1.4 31.1 2.8 584.8 0.5 159.8 3.4 562.0 0.7 0.3 0.8 6.5 35.7 7.5 724.7 0.0 8.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 0.7 0.2 0.1 0.0 0.2 0.6 0.0 0.0 0.0 27.8 0.2 0.0 0.3 4.0 0.0 0.0 0.2 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.6 0.0 44.2 0.1 0.2 0.2 90.0 0.0 2.3 0.0 1.2 0.0 179.5 0.2 0.1 0.0 368.6 0.4 0.0 12.2 0.0 0.0 0.0 0.1 3.2 0.0 0.9 0.5 1.0 0.9 0.0 0.3 0.3 0.1 0.0 0.2 0.0 1.2 0.6 0.4 0.1 0.0 0.2 0.0 0.0 0.3 0.1 0.1 0.1 2.1 0.1 506.5 627.9 551.3 890.2 421.4 525.8 749.3 660.7 649.9 584.8 562.0 724.7 0.8 9.6 1.1 1.6 2.8 0.8 6.3 8.5 0.6 0.1 6.2 1.9 2.2 7.2 35.9 3.7 0.0 0.2 0.4 182.6 1.9 2.9 15.6 9.4 11.1 0.4 8.4 0.0 1.6 22.5 0.1 0.8 202.9 11.8 4.5 0.0 0.4 0.1 0.1 0.0 2.5 371.4 18.3 0.0 2.5 16.1 0.3 1.7 16.0 0.0 0.0 0.8 0.0 538.8 718.8 22.9 102.0 0.0 1.0 21.3 12.0 0.1 100.5 0.5 0.0 1.4 2.2 15.4 6.1 0.3 0.3 0.0 1.7 0.4 35.6 56.7 BCL2L12 ENSG00000126453 "BCL2 like 12" Q9HB09 19 49665142-49673916 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 126.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020856 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "Plasma membrane" "HPA020856: AB_1845320" "unprognostic (2.59e-1)" "unprognostic (3.96e-2)" "unprognostic (2.24e-1)" "unprognostic (5.72e-2)" "unprognostic (3.64e-1)" "unprognostic (3.68e-2)" "unprognostic (6.80e-3)" "unprognostic (3.87e-3)" "unprognostic (6.12e-2)" "unprognostic (8.90e-2)" "unprognostic (1.60e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (8.75e-5)" "unprognostic (8.67e-2)" "unprognostic (3.62e-2)" "unprognostic (2.37e-1)" "unprognostic (2.56e-1)" 8.5 8.5 3.8 14.7 3.9 18.2 9.5 3.9 5.1 8.3 5.0 11.9 10.5 9.9 3.2 13.4 9.5 6.5 9.4 3.6 3.8 7.8 16.6 9.6 20.6 4.4 4.2 9.7 15.5 4.5 2.7 10.3 4.1 11.3 7.3 1.7 11.7 5.0 14.0 8.5 11.9 6.8 4.1 16.7 11.7 10.1 4.1 17.3 7.6 13.5 15.8 9.6 8.7 4.3 105.2 63.7 49.8 94.8 12.6 12.6 56.9 58.2 23.3 57.2 60.6 89.2 55.4 58.4 26.7 20.2 32.4 49.7 46.3 39.4 30.7 74.1 97.4 53.1 43.5 62.0 11.4 56.6 62.2 15.5 19.0 64.3 18.2 11.5 38.7 79.2 138.8 73.3 30.8 59.1 67.6 91.8 62.4 61.8 77.4 86.6 54.3 62.7 24.8 52.0 0.9 29.4 59.5 79.0 41.8 35.6 33.0 70.3 22.8 64.1 75.2 45.5 96.4 61.2 102.4 114.3 27.2 78.0 64.3 11.0 7.4 17.0 12.5 12.2 14.6 14.8 13.2 12.3 6.5 14.6 12.8 13.1 10.9 15.8 8.6 25.9 14.4 6.3 3.8 3.9 3.9 5.1 3.6 3.8 4.4 4.2 4.1 4.1 4.1 4.3 10.2 9.6 13.1 3.3 22.1 32.2 37.4 23.3 14.2 1.0 35.2 34.2 5.0 10.0 16.5 5.5 0.0 70.3 18.2 14.6 7.9 25.7 8.3 17.0 11.5 13.2 6.7 18.5 0.2 25.8 126.3 16.2 9.2 20.1 9.5 18.9 11.0 13.1 37.6 0.0 0.2 15.7 18.3 12.6 16.1 6.4 6.5 15.5 26.6 1.0 22.1 3.5 24.7 0.0 1.6 34.5 16.6 6.0 44.3 20.5 6.5 10.4 12.6 1.2 13.1 14.0 15.1 11.6 22.3 19.7 19.5 55.7 15.7 11.7 23.3 27.7 BCL3 "BCL4, D19S37" ENSG00000069399 "BCL3 transcription coactivator" P20749 19 44747705-44760044 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 161.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 172.4;Squamous epithelial cells: 146.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 5.5;neutrophil: 19.8" "Lineage enriched" "Detected in all" 6 "granulocytes: 19.8" "Cell line enhanced" "Detected in many" "HDLM-2: 67.3;Karpas-707: 54.1;SiHa: 69.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002051, HPA047514" Approved Supported Nucleoplasm,Vesicles,Midbody Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Vesicles, Midbody" "CAB002051: AB_563428, HPA047514: AB_2680074" "prognostic favorable (9.67e-4)" "unprognostic (8.82e-2)" "unprognostic (2.81e-1)" "unprognostic (7.54e-2)" "prognostic unfavorable (4.01e-4)" "unprognostic (3.49e-2)" "unprognostic (2.34e-3)" "unprognostic (2.79e-1)" "prognostic favorable (3.74e-4)" "unprognostic (2.09e-2)" "unprognostic (9.23e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (3.13e-14)" "unprognostic (8.24e-2)" "unprognostic (1.36e-1)" "unprognostic (3.77e-2)" "unprognostic (3.04e-2)" 65.1 43.6 6.7 25.0 6.3 54.0 37.2 6.4 7.8 26.8 7.9 39.7 32.2 26.8 1.7 67.5 35.9 13.4 36.3 5.9 7.2 56.6 161.8 87.3 11.6 11.6 7.8 23.7 37.4 3.1 25.2 7.9 8.1 43.4 9.3 1.3 40.9 8.9 17.8 28.3 44.2 11.7 8.0 58.7 35.9 9.6 8.5 6.6 36.8 4.9 12.7 37.6 37.7 6.4 9.8 33.5 0.7 17.5 6.1 12.6 1.7 5.8 6.3 3.7 5.3 6.9 17.8 9.5 13.4 11.5 18.5 10.5 2.4 9.9 2.3 67.3 0.6 1.1 18.9 9.3 14.6 0.7 28.2 22.5 7.8 8.1 9.9 16.6 10.0 0.0 1.2 54.1 2.2 8.4 0.0 7.4 0.9 15.1 12.8 4.3 6.5 3.4 16.5 19.9 0.0 0.9 69.7 35.7 1.9 1.1 12.7 7.6 16.8 11.8 11.6 18.5 2.2 50.1 21.4 10.1 22.1 1.2 9.2 0.4 2.7 5.5 0.8 1.8 1.1 1.5 1.0 1.3 2.6 1.3 0.5 0.7 19.8 2.3 1.1 3.1 1.7 1.0 6.7 6.3 6.4 7.8 5.9 7.2 11.6 7.8 8.1 8.0 8.5 6.4 56.3 19.2 51.3 2.6 43.9 46.7 38.8 22.4 172.4 2.3 106.8 62.0 3.0 42.9 28.6 12.9 0.0 0.6 33.4 60.6 9.8 31.8 11.8 49.4 34.2 76.3 21.5 4.2 0.5 68.7 6.8 47.8 128.0 70.0 38.0 1.4 38.9 35.5 16.1 8.4 0.8 56.2 8.2 30.5 110.8 2.7 13.4 86.6 40.9 1.0 28.4 2.2 2.1 0.0 0.1 43.0 40.0 4.5 100.4 58.9 56.6 17.7 20.5 0.6 6.6 43.3 40.1 0.5 2.0 146.0 61.1 1.4 46.2 0.3 34.5 51.2 BCL6B "BAZF, ZBTB28, ZNF62" ENSG00000161940 "BCL6B transcription repressor" Q8N143 17 7023050-7030290 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 37.8;Endothelial cells: 45.0;Hepatic stellate cells: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 18.2;HMC-1: 53.2;HUVEC TERT2: 96.2;TIME: 38.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA059147, HPA075112" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Vesicles, Plasma membrane" "HPA059147: AB_2683928, HPA075112: AB_2732279" "unprognostic (5.61e-2)" "unprognostic (9.43e-3)" "unprognostic (2.33e-2)" "unprognostic (2.12e-1)" "unprognostic (1.40e-1)" "prognostic favorable (8.56e-5)" "unprognostic (2.81e-1)" "unprognostic (2.28e-2)" "unprognostic (4.81e-2)" "unprognostic (1.80e-1)" "unprognostic (6.10e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (7.14e-2)" "unprognostic (1.11e-1)" "unprognostic (4.29e-2)" "unprognostic (4.26e-2)" 29.8 5.6 8.1 5.7 7.0 0.1 15.4 6.2 9.2 5.7 4.4 4.4 3.2 7.7 0.7 3.8 5.1 13.4 23.3 6.5 6.9 13.4 4.0 28.9 5.5 7.8 7.1 2.9 3.8 3.1 5.5 19.9 7.3 4.5 2.2 0.6 4.0 3.5 11.5 4.4 4.9 7.7 6.6 13.0 4.3 2.0 10.1 2.0 12.0 14.7 2.1 7.9 4.8 6.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 18.2 0.0 0.0 0.5 0.0 53.2 0.0 0.0 0.0 0.1 0.0 96.2 0.2 3.4 0.4 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 38.2 0.8 0.2 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.2 9.2 6.5 6.9 7.8 7.1 7.3 6.6 10.1 6.7 37.8 3.2 4.2 0.0 0.5 2.2 0.0 0.0 0.0 0.0 0.2 0.3 2.9 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.3 45.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.1 23.6 0.2 0.1 0.0 0.0 0.2 0.0 1.9 2.3 0.0 0.0 0.3 3.6 4.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.4 0.0 0.1 0.0 0.2 0.0 0.9 0.8 0.6 1.5 0.4 1.3 0.1 0.2 0.9 0.0 0.5 BCL7A BCL7 ENSG00000110987 "BAF chromatin remodeling complex subunit BCL7A" Q4VC05 12 122019422-122062044 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 77.9;Horizontal cells: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 1.0;naive B-cell: 2.1;plasmacytoid DC: 2.8" "Group enriched" "Detected in many" 14 "B-cells: 2.1;dendritic cells: 2.8" "Cell line enhanced" "Detected in many" "Daudi: 71.9;MOLT-4: 71.4;U-698: 95.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019762 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Vesicles" "HPA019762: AB_10962489" "unprognostic (3.27e-1)" "unprognostic (2.97e-2)" "prognostic unfavorable (6.81e-4)" "unprognostic (1.35e-1)" "unprognostic (1.46e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (5.18e-1)" "unprognostic (5.13e-2)" "unprognostic (1.06e-2)" "unprognostic (3.13e-1)" "unprognostic (3.11e-1)" "prognostic favorable (1.54e-6)" "unprognostic (4.86e-2)" "unprognostic (8.56e-2)" "unprognostic (6.16e-3)" "unprognostic (1.51e-2)" 3.1 2.8 9.2 5.2 10.8 9.8 5.7 8.9 11.2 5.1 0.0 4.0 2.5 4.5 6.7 2.8 8.4 2.4 7.6 9.6 3.2 9.1 4.9 3.9 16.2 3.5 4.7 3.7 9.1 9.1 5.2 1.9 3.3 5.1 2.9 4.1 7.0 5.9 11.5 8.2 3.0 3.3 2.9 5.8 3.8 2.2 4.5 24.7 9.0 8.9 15.4 4.8 4.8 9.1 6.0 6.2 29.9 17.9 2.2 1.1 6.0 3.2 3.1 5.3 4.9 3.2 2.4 71.9 9.2 2.7 2.7 8.8 22.7 16.4 5.3 0.0 25.0 3.5 0.4 5.5 6.5 13.8 8.1 4.7 21.3 3.9 26.7 8.1 7.7 42.3 18.3 0.0 4.3 10.7 71.4 1.3 10.7 9.7 11.0 33.2 8.5 1.2 13.4 14.3 26.5 28.9 3.4 0.8 13.1 7.7 17.4 13.6 6.9 0.7 5.1 10.0 6.1 9.4 5.4 95.8 2.1 9.3 6.7 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.3 2.1 0.1 0.1 0.1 0.0 0.0 2.8 0.0 0.1 9.2 10.8 8.9 11.2 9.6 3.2 3.5 4.7 3.3 2.9 4.5 9.1 4.6 22.4 9.2 8.5 51.6 35.9 77.9 26.5 22.8 41.8 32.7 33.5 28.6 42.9 19.0 38.6 18.8 1.5 38.1 5.9 58.7 33.5 6.9 39.3 10.9 5.6 21.5 18.7 15.9 10.9 0.9 11.9 7.1 26.8 10.8 16.6 5.3 18.6 4.2 107.7 19.9 8.6 16.2 2.2 14.3 18.7 14.0 9.8 12.4 1.9 6.2 5.5 1.0 13.6 16.2 10.0 6.9 7.9 6.8 29.9 1.6 31.3 20.7 14.0 6.6 34.7 16.6 0.7 7.7 5.3 30.1 0.5 3.2 42.9 11.7 32.3 BDKRB2 BK-2 ENSG00000168398 "Bradykinin receptor B2" P30411 14 96204679-96244166 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 41.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.3;Endothelial cells: 18.2;Fibroblasts: 25.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 49.2;BJ hTERT+: 94.5;U-87 MG: 39.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA003551, HPA050841" Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA003551: , HPA050841: AB_2681254" "unprognostic (1.03e-1)" "unprognostic (7.90e-2)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (8.79e-3)" "unprognostic (2.68e-2)" "unprognostic (1.93e-1)" "unprognostic (4.66e-2)" "unprognostic (1.94e-1)" "unprognostic (2.84e-2)" "unprognostic (3.19e-1)" "unprognostic (1.72e-1)" "unprognostic (3.32e-3)" "unprognostic (3.11e-2)" "unprognostic (9.40e-2)" "unprognostic (9.90e-2)" "unprognostic (1.49e-2)" 14.0 1.4 0.8 5.5 1.0 0.0 5.8 3.8 1.1 15.6 0.9 12.4 7.9 6.7 2.4 17.2 7.2 20.8 1.2 0.9 0.8 13.4 0.7 2.5 0.3 4.9 1.3 1.0 9.4 0.9 0.8 1.3 5.0 4.8 12.2 0.0 3.5 6.2 0.9 5.4 9.7 10.2 1.0 0.1 4.9 0.2 1.5 0.9 3.6 1.8 1.7 41.1 15.4 1.2 1.7 6.1 0.1 11.0 16.2 49.2 0.0 5.5 94.5 3.2 3.7 0.3 10.4 0.0 0.2 8.7 3.7 14.8 0.0 2.4 2.8 1.2 0.1 0.0 1.1 0.0 7.8 0.0 0.0 15.1 7.5 9.4 4.7 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.1 0.1 20.4 0.0 0.0 2.2 0.0 3.2 0.0 3.4 1.1 1.8 15.6 0.1 2.1 1.0 0.0 0.0 0.3 0.3 3.3 0.1 0.2 0.0 0.0 39.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 1.0 3.8 1.1 0.9 0.8 4.9 1.3 5.0 1.0 1.5 1.2 8.2 3.2 3.1 0.0 0.0 9.2 0.7 5.3 6.8 0.0 0.2 0.5 0.6 10.0 11.6 9.2 0.0 1.2 0.0 19.3 7.9 11.5 0.0 7.5 16.1 18.2 7.1 0.0 1.8 3.8 3.6 25.8 1.1 4.6 0.0 0.0 3.3 0.2 0.2 0.0 0.4 7.2 8.2 0.0 15.2 0.0 0.9 0.4 5.4 0.0 0.0 0.0 0.0 1.0 1.9 6.9 6.2 1.2 0.0 1.0 10.6 0.2 12.5 0.0 0.0 4.5 1.2 0.0 0.0 15.3 5.8 4.0 0.3 0.1 0.9 2.9 BEND7 "C10orf30, FLJ40283" ENSG00000165626 "BEN domain containing 7" Q8N7W2 10 13438484-13528974 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 167.3;Late spermatids: 268.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 17.5;hTERT-RPE1: 17.3" HPA037835 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nucleoli fibrillar center, Vesicles" "HPA037835: AB_10669722" "unprognostic (6.22e-2)" "unprognostic (1.80e-1)" "unprognostic (1.89e-1)" "unprognostic (1.33e-2)" "unprognostic (1.18e-2)" "unprognostic (4.62e-3)" "unprognostic (3.24e-3)" "unprognostic (3.52e-2)" "unprognostic (1.26e-1)" "unprognostic (5.02e-2)" "unprognostic (1.12e-1)" "unprognostic (1.06e-1)" "unprognostic (4.19e-3)" "unprognostic (1.57e-1)" "unprognostic (1.60e-1)" "unprognostic (1.58e-1)" "unprognostic (5.20e-3)" 8.0 6.0 4.7 2.4 4.9 0.7 9.4 6.5 4.7 7.4 4.9 11.2 16.5 7.3 13.6 2.2 12.4 6.5 7.4 5.0 4.9 18.5 9.0 9.1 1.1 5.1 5.9 8.3 12.1 14.8 10.3 4.3 5.9 5.7 6.6 15.4 15.1 6.5 16.4 3.2 19.3 6.1 4.7 3.0 11.2 16.3 5.6 0.5 23.5 13.3 1.0 6.8 4.4 4.4 9.9 5.9 6.0 2.2 0.1 0.0 8.7 3.8 0.1 9.3 5.6 2.4 17.5 0.0 5.1 7.3 5.2 0.4 9.8 2.1 8.3 0.0 8.7 0.0 0.0 11.4 3.9 0.0 0.0 0.2 5.7 1.2 0.0 17.3 10.3 1.4 4.3 0.0 9.3 4.0 0.1 0.0 1.8 0.0 1.0 0.0 4.4 0.0 8.0 1.3 0.4 4.7 10.7 0.0 0.1 9.1 0.1 4.7 9.2 1.1 13.8 11.6 4.8 0.0 0.0 0.0 3.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 4.7 4.9 6.5 4.7 5.0 4.9 5.1 5.9 5.9 4.7 5.6 4.4 33.6 22.4 11.6 23.5 1.9 3.4 23.6 1.1 1.8 14.4 15.4 11.4 11.0 22.8 9.8 20.2 8.4 3.0 2.6 13.2 3.9 13.0 167.3 25.0 5.8 16.7 7.8 0.0 7.5 16.5 2.9 8.0 9.7 36.2 6.3 14.7 22.5 9.6 3.0 1.7 10.2 8.5 6.1 9.4 1.9 268.7 5.0 2.5 3.6 24.4 4.5 20.3 12.3 47.7 0.7 21.8 9.5 6.0 0.5 23.9 45.2 52.0 9.7 32.2 0.0 14.1 8.4 21.5 20.0 3.3 1.8 2.5 3.5 3.4 10.3 36.1 BHLHE41 "BHLHB3, DEC2, SHARP-1, SHARP1" ENSG00000123095 "Basic helix-loop-helix family member e41" Q9C0J9 12 26120030-26125037 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 122.4;skeletal muscle: 92.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 347.5;Cone photoreceptor cells: 183.5;Horizontal cells: 250.7;Muller glia cells: 239.8;Rod photoreceptor cells: 309.5" "Cancer enhanced" "Detected in all" "thyroid cancer: 78.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.9" "Lineage enriched" "Detected in single" 20 "B-cells: 1.9" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 92.4;RT4: 126.6;U-266/70: 52.6;U-87 MG: 44.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056035, HPA077617" Supported Nucleoplasm,Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 15: RT4 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm Vesicles "HPA056035: AB_2683017, HPA077617: " "unprognostic (1.57e-3)" "unprognostic (1.57e-2)" "unprognostic (2.32e-2)" "unprognostic (6.62e-2)" "unprognostic (2.18e-1)" "unprognostic (2.29e-1)" "unprognostic (5.86e-2)" "unprognostic (2.59e-1)" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" "unprognostic (2.96e-2)" "prognostic unfavorable (8.73e-5)" "unprognostic (5.23e-2)" "unprognostic (1.65e-1)" "unprognostic (5.61e-3)" "prognostic favorable (1.09e-4)" 10.6 14.6 35.4 7.4 46.7 0.5 13.6 52.5 35.2 38.8 11.8 9.5 2.7 8.1 19.3 3.2 45.5 18.3 20.0 30.5 39.5 3.8 0.7 11.6 7.9 58.1 48.7 12.9 7.7 6.5 16.7 10.5 62.3 9.7 11.1 122.4 18.4 14.0 92.5 5.6 6.3 4.1 60.2 9.1 4.9 4.3 49.8 6.3 57.8 12.9 17.9 21.3 9.9 67.1 11.4 0.1 0.3 0.0 20.4 9.4 4.7 2.2 3.8 0.4 1.4 0.0 13.4 0.0 1.9 4.4 31.4 11.3 0.4 1.9 1.1 0.1 1.7 1.0 0.2 0.0 0.9 5.7 0.3 1.5 1.1 7.8 15.0 92.4 0.0 0.1 0.0 39.6 2.4 1.3 0.0 3.9 10.4 3.7 7.8 0.0 1.9 31.6 4.9 126.6 0.2 0.2 1.4 0.6 29.7 0.6 0.0 0.2 6.7 7.1 8.2 0.8 5.9 52.6 32.3 0.1 44.9 4.4 4.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.4 46.7 52.5 35.2 30.5 39.5 58.1 48.7 62.3 60.2 49.8 67.1 1.6 0.0 1.1 46.0 25.0 6.0 59.8 34.1 10.8 347.5 9.2 56.0 46.7 37.1 11.2 29.5 183.5 26.6 0.2 55.0 0.0 40.6 0.6 78.5 27.1 12.0 13.1 0.0 10.1 21.9 3.6 22.7 3.1 60.8 5.7 0.2 2.5 0.1 91.1 250.7 12.4 4.4 0.0 4.0 4.4 1.3 30.1 39.8 14.2 120.9 27.4 239.8 0.0 22.1 56.2 21.9 12.0 26.7 61.8 49.0 0.4 2.3 34.8 309.5 6.6 13.0 7.5 0.5 3.7 3.5 3.3 7.1 2.4 2.3 5.0 83.8 BICD1 ENSG00000151746 "BICD cargo adaptor 1" Q96G01 12 32106835-32383633 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 29.8" "Group enriched" "Detected in many" 5 "Astrocytes: 198.8;Excitatory neurons: 267.2;Inhibitory neurons: 331.5;Microglial cells: 96.5;Oligodendrocyte precursor cells: 167.4;Oligodendrocytes: 131.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NTERA-2: 73.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041309 Approved Uncertain Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA041309: AB_10804000" "unprognostic (1.40e-1)" "unprognostic (1.18e-2)" "unprognostic (1.73e-2)" "unprognostic (2.10e-1)" "unprognostic (2.06e-1)" "unprognostic (1.08e-1)" "unprognostic (1.90e-6)" "unprognostic (5.93e-2)" "unprognostic (4.57e-1)" "unprognostic (3.64e-1)" "unprognostic (8.19e-2)" "unprognostic (9.66e-2)" "prognostic unfavorable (2.33e-7)" "unprognostic (1.72e-1)" "unprognostic (1.74e-1)" "unprognostic (5.37e-2)" "unprognostic (1.36e-1)" 5.8 3.8 7.8 6.0 6.2 3.2 4.5 29.8 10.3 13.7 0.0 4.0 2.1 9.8 4.9 2.0 9.8 4.7 5.3 6.7 7.0 6.0 1.2 6.0 6.8 4.4 6.0 20.6 1.8 6.1 6.9 8.7 7.3 5.2 2.8 7.9 2.7 2.6 3.8 2.3 3.8 5.4 2.6 8.0 2.8 3.1 6.0 7.4 6.2 3.4 5.3 4.6 4.1 8.5 14.5 9.9 7.1 4.3 6.9 9.3 8.1 16.4 6.7 16.5 11.6 12.8 9.6 21.0 13.3 14.5 18.8 6.7 36.2 13.8 25.7 14.9 10.6 28.3 9.9 6.2 7.7 22.8 16.8 5.5 6.8 19.4 15.9 25.4 16.8 22.8 13.0 41.7 6.5 5.8 22.3 8.7 73.7 6.2 11.0 16.7 23.9 15.7 21.7 8.3 31.7 17.4 12.5 0.9 12.8 48.7 8.3 5.0 16.6 25.1 24.0 18.6 23.7 13.7 20.9 44.3 16.8 10.0 27.3 0.0 0.5 0.0 1.5 0.2 2.3 2.4 1.4 0.9 0.8 2.0 1.8 1.5 0.1 1.9 0.0 1.9 2.4 0.8 7.8 6.2 29.8 10.3 6.7 7.0 4.4 6.0 7.3 2.6 6.0 8.5 15.1 16.0 1.1 198.8 22.0 0.4 8.2 13.6 6.8 30.5 5.4 6.3 8.3 1.5 9.1 9.2 37.5 0.4 10.7 0.7 1.9 9.1 0.6 11.7 26.2 17.0 6.6 9.2 267.2 4.7 0.5 12.6 1.1 34.2 0.0 35.1 13.2 0.5 6.5 23.5 331.5 1.2 16.2 1.3 4.2 1.2 4.1 5.1 8.8 96.5 4.2 39.2 4.1 167.4 131.7 8.3 0.5 4.5 34.5 7.0 0.6 2.7 2.6 19.3 0.0 18.1 12.3 6.9 9.2 3.9 2.4 0.3 10.7 28.1 2.6 3.7 BICDL1 "BICDR-1, CCDC64, FLJ26450" ENSG00000135127 "BICD family like cargo adaptor 1" Q6ZP65 12 119989869-120094494 "Predicted intracellular proteins" "Neurogenesis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 128.7;pituitary gland: 80.2" "Cell type enhanced" "Detected in some" "Collecting duct cells: 12.9;dendritic cells: 13.7;Distal tubular cells: 23.5;Plasma cells: 12.8;Proximal tubular cells: 27.3;T-cells: 17.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTCEpi: 48.9;MCF7: 27.7;OE19: 25.2;SCLC-21H: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061116 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" Vesicles "HPA061116: AB_2684433" "unprognostic (2.17e-1)" "prognostic favorable (6.50e-4)" "unprognostic (1.68e-3)" "unprognostic (3.05e-2)" "unprognostic (6.81e-4)" "prognostic favorable (3.15e-4)" "prognostic unfavorable (6.84e-4)" "unprognostic (5.11e-2)" "unprognostic (3.18e-2)" "unprognostic (4.63e-2)" "unprognostic (3.31e-3)" "unprognostic (7.26e-2)" "prognostic favorable (3.93e-5)" "prognostic favorable (1.21e-5)" "unprognostic (1.36e-1)" "unprognostic (1.03e-1)" "unprognostic (2.15e-1)" 24.8 2.7 7.6 10.8 8.8 3.0 2.9 5.4 13.3 7.4 0.2 3.2 4.0 0.7 37.5 35.8 4.2 4.1 2.9 7.6 10.9 128.7 5.6 6.0 23.8 5.6 3.4 1.1 7.7 2.5 80.2 1.1 5.6 4.9 3.1 67.6 8.3 1.0 0.4 64.2 7.3 0.6 2.6 7.1 20.9 40.8 6.9 18.2 24.4 0.0 15.5 3.1 21.5 6.6 3.5 10.6 0.6 0.0 0.9 0.0 12.6 0.0 0.0 0.0 0.0 9.5 5.9 16.8 4.4 0.0 9.1 7.9 1.3 1.6 0.0 1.2 1.7 0.1 4.7 18.3 0.0 2.1 17.1 0.0 48.9 0.0 0.6 0.0 0.0 14.1 0.5 2.1 0.0 27.7 12.3 0.2 21.1 25.2 5.0 1.3 0.9 4.5 6.2 8.4 30.8 2.2 3.6 9.7 2.6 5.1 22.4 8.3 0.0 0.1 2.9 0.0 0.2 4.2 17.1 6.5 0.6 2.4 1.7 0.3 0.0 0.0 1.2 0.0 0.4 0.1 1.2 1.0 0.0 0.1 0.9 0.7 0.0 0.0 0.3 0.0 0.2 0.2 7.6 8.8 5.4 13.3 7.6 10.9 5.6 3.4 5.6 2.6 6.9 6.6 0.6 0.0 1.3 0.0 6.8 0.0 0.0 0.0 0.0 0.0 2.8 2.2 0.0 0.0 1.3 12.9 0.0 1.0 13.7 0.0 23.5 1.1 0.0 3.1 1.0 0.1 0.0 0.0 0.0 3.5 0.6 2.7 0.0 7.7 1.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.9 0.0 0.0 12.8 0.0 0.0 27.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 17.6 0.7 0.0 0.0 BIRC6 BRUCE ENSG00000115760 "Baculoviral IAP repeat containing 6" Q9NR09 2 32357028-32618899 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 272.0;Inhibitory neurons: 291.3;Oligodendrocytes: 361.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 9.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 9.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA074409, HPA074738" Approved Supported "Golgi apparatus,Vesicles,Mitotic spindle" Yes No "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Golgi apparatus, Vesicles" "Mitotic spindle" "HPA074409: , HPA074738: AB_2686710" "unprognostic (3.38e-2)" "unprognostic (8.13e-3)" "unprognostic (8.88e-2)" "unprognostic (7.06e-3)" "unprognostic (6.69e-3)" "unprognostic (9.01e-2)" "unprognostic (4.51e-2)" "unprognostic (2.07e-1)" "unprognostic (1.32e-1)" "unprognostic (1.86e-1)" "unprognostic (4.49e-2)" "unprognostic (4.00e-2)" "unprognostic (2.07e-2)" "unprognostic (1.30e-1)" "unprognostic (4.61e-1)" "unprognostic (7.32e-2)" "unprognostic (3.37e-1)" 4.6 4.7 3.1 6.7 9.7 11.3 8.9 13.9 5.7 7.7 6.3 7.6 5.0 6.8 5.2 5.3 6.2 5.8 4.9 4.6 3.7 7.6 8.9 5.4 9.6 6.4 5.5 12.0 14.7 10.9 2.9 6.9 7.3 6.2 7.5 15.5 5.5 5.9 6.1 6.7 5.4 6.1 4.4 8.5 7.1 6.8 5.6 14.7 11.4 8.8 9.7 7.2 3.1 16.3 21.7 17.8 16.1 7.9 14.9 19.1 11.3 10.8 14.1 11.0 11.3 14.2 5.7 23.6 7.3 19.7 13.2 10.1 22.9 15.1 13.9 18.8 10.5 31.2 11.3 10.7 7.9 32.4 11.9 12.4 6.9 18.0 16.2 10.1 17.7 5.4 25.6 10.0 11.9 9.3 15.5 7.5 11.7 9.2 10.5 14.6 26.6 8.2 9.2 23.4 11.7 18.4 18.6 10.8 8.2 12.5 6.4 11.5 28.7 13.0 13.3 9.1 15.3 13.9 20.0 30.6 10.1 15.1 8.7 9.7 0.9 0.6 1.3 0.7 1.8 0.8 1.0 1.2 0.7 1.8 1.1 1.4 1.5 1.6 1.5 1.6 1.0 0.5 3.1 9.7 13.9 5.7 4.6 3.7 6.4 5.5 7.3 4.4 5.6 16.3 53.9 32.1 30.5 239.3 74.8 46.0 28.6 34.7 41.5 60.8 40.0 23.4 45.8 38.6 42.7 36.8 191.8 35.0 93.4 70.1 1.9 26.9 45.9 39.3 58.0 49.8 32.5 34.3 272.0 31.2 22.0 39.7 68.3 63.1 29.9 52.1 45.7 47.5 29.8 69.0 291.3 43.3 26.4 54.7 60.0 17.6 45.4 59.1 23.2 202.4 67.2 34.9 64.9 231.8 361.3 34.3 30.3 59.0 70.9 46.4 48.5 22.6 30.6 88.2 39.5 56.0 49.1 53.7 46.2 49.7 54.8 38.0 72.4 52.8 45.3 44.0 BLNK "BASH, bca, BLNK-s, Ly57, SLP-65, SLP65" ENSG00000095585 "B cell linker" Q8WV28 10 96189171-96271587 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "B-cell activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 70.5" "Cell type enhanced" "Detected in many" "B-cells: 94.2;dendritic cells: 64.0;Microglial cells: 157.4;Plasma cells: 80.4;Proximal enterocytes: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "memory B-cell: 161.2;naive B-cell: 140.5;plasmacytoid DC: 231.5" "Group enriched" "Detected in many" 101 "B-cells: 161.2;dendritic cells: 231.5" "Group enriched" "Detected in some" 6 "Daudi: 68.7;REH: 168.4;RPMI-8226: 94.4;U-698: 251.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009333, CAB016291, HPA038309, HPA038310" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" Vesicles "CAB009333: AB_2290422, CAB016291: AB_626752, HPA038309: AB_2675945, HPA038310: AB_2675946" "unprognostic (4.86e-2)" "unprognostic (6.05e-3)" "unprognostic (1.00e-2)" "unprognostic (2.73e-2)" "unprognostic (2.29e-1)" "unprognostic (1.63e-3)" "unprognostic (1.08e-2)" "unprognostic (5.19e-2)" "unprognostic (2.97e-1)" "unprognostic (1.02e-1)" "unprognostic (8.94e-2)" "unprognostic (3.73e-1)" "unprognostic (1.84e-2)" "unprognostic (5.23e-2)" "unprognostic (9.76e-2)" "unprognostic (1.46e-3)" "prognostic favorable (2.67e-6)" 2.2 3.2 3.8 27.5 3.4 10.1 6.3 2.4 4.1 7.1 13.9 16.9 38.9 2.4 30.1 39.9 6.1 10.8 1.0 3.5 5.1 28.5 39.2 6.6 57.6 4.7 4.0 1.5 12.1 17.4 1.8 6.4 5.0 7.3 18.2 1.4 10.9 13.2 0.5 8.0 34.0 3.0 3.8 54.0 29.2 1.3 4.9 10.6 11.6 1.1 70.5 9.9 15.8 5.2 0.3 0.1 0.1 0.2 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.2 0.2 68.7 0.4 0.0 0.3 0.6 0.1 0.8 0.1 5.5 0.2 0.3 0.3 0.1 0.0 0.1 1.4 0.1 8.7 0.0 0.0 0.1 0.0 0.8 0.3 6.4 0.0 0.7 0.4 0.2 0.2 0.2 0.0 168.4 0.3 94.4 0.9 13.0 0.3 0.3 0.2 15.1 0.1 0.2 23.7 1.1 0.2 0.2 0.8 0.1 0.2 5.4 0.4 251.4 0.1 0.5 0.1 0.3 1.6 0.2 0.3 1.3 0.1 161.2 0.3 0.2 20.6 140.5 0.1 0.1 1.1 1.9 0.1 231.5 0.6 8.1 3.8 3.4 2.4 4.1 3.5 5.1 4.7 4.0 5.0 3.8 4.9 5.2 0.4 6.4 7.7 0.7 94.2 1.1 21.0 13.1 21.1 0.0 4.1 3.4 1.2 30.0 7.3 40.5 0.0 23.0 64.0 9.2 27.4 14.6 3.1 14.4 1.9 0.3 4.9 5.3 1.0 13.8 17.5 0.7 35.7 22.9 1.3 0.0 2.9 27.8 22.8 0.0 1.3 19.4 30.5 9.0 13.8 1.1 0.3 18.2 1.8 157.4 4.8 0.0 0.0 2.5 0.9 4.4 22.4 0.0 80.4 5.1 64.6 2.3 3.4 0.0 6.6 0.3 0.7 1.6 0.1 34.7 1.4 41.5 3.6 0.5 22.5 23.8 BLOC1S4 "BCAS4L, CNO, FLJ11230" ENSG00000186222 "Biogenesis of lysosomal organelles complex 1 subunit 4" Q9NUP1 4 6716174-6717664 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043840 Approved Approved Vesicles,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles Cytosol "HPA043840: AB_10965701" "unprognostic (3.09e-1)" "unprognostic (8.40e-2)" "unprognostic (1.78e-1)" "unprognostic (1.82e-1)" "unprognostic (7.49e-2)" "unprognostic (1.70e-1)" "prognostic unfavorable (1.06e-4)" "unprognostic (3.28e-2)" "unprognostic (2.72e-1)" "unprognostic (1.19e-2)" "unprognostic (1.04e-1)" "unprognostic (7.51e-2)" "unprognostic (1.80e-1)" "unprognostic (3.53e-1)" "unprognostic (1.76e-1)" "unprognostic (9.24e-3)" "unprognostic (5.62e-3)" 8.6 11.7 8.0 7.9 8.2 9.8 8.9 8.3 8.7 9.4 9.1 8.9 9.2 9.9 7.1 11.1 9.3 6.5 8.0 8.3 7.7 10.0 11.3 6.3 12.1 8.1 8.2 12.0 7.9 5.6 7.2 7.7 8.3 9.4 5.7 4.3 8.2 6.4 10.8 8.6 11.4 5.1 8.4 13.1 8.8 6.3 8.3 8.9 7.6 5.7 8.6 9.6 8.6 8.6 15.3 10.3 15.2 15.6 11.7 15.0 30.5 12.0 13.2 11.0 9.7 9.2 16.0 14.4 12.6 10.9 15.5 10.1 8.6 14.0 8.4 11.7 14.1 22.0 10.3 23.2 14.3 10.8 19.7 14.2 13.6 8.7 7.5 10.8 10.3 12.3 29.3 12.6 11.6 15.1 17.6 37.5 19.7 11.2 20.0 17.9 16.8 13.0 15.3 13.3 13.1 17.5 9.9 7.1 22.7 11.6 22.4 20.8 11.6 10.0 8.9 11.8 15.4 18.8 19.8 19.4 11.2 19.6 16.3 2.5 2.7 14.0 4.4 4.6 4.5 6.3 5.4 4.8 3.6 5.2 8.4 4.5 1.4 2.5 3.1 3.4 5.1 1.7 8.0 8.2 8.3 8.7 8.3 7.7 8.1 8.2 8.3 8.4 8.3 8.6 18.7 6.4 5.9 3.9 40.8 23.6 35.2 4.9 26.7 29.1 25.2 27.8 5.3 21.5 5.7 23.9 6.2 65.1 49.5 21.7 25.4 9.7 2.5 28.6 28.0 20.2 11.4 26.5 6.8 7.0 93.1 27.8 21.9 25.3 3.8 18.7 32.5 23.6 35.8 30.3 6.6 22.8 4.1 24.0 22.2 1.6 32.3 16.6 30.2 5.6 18.1 38.4 60.8 4.5 8.3 9.9 33.9 22.6 19.7 40.3 33.9 51.3 4.6 24.7 6.6 26.6 20.0 16.0 14.3 23.1 24.9 63.3 47.7 39.1 24.2 34.8 BLOC1S5 "dJ303A1.3, MU, MUTED" ENSG00000188428 "Biogenesis of lysosomal organelles complex 1 subunit 5" Q8TDH9 6 8013567-8064396 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 41.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025613, HPA077525" Uncertain Supported Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "CAB025613: , HPA077525: AB_2686843" "unprognostic (1.54e-1)" "unprognostic (8.21e-2)" "unprognostic (1.26e-2)" "unprognostic (1.24e-2)" "unprognostic (1.92e-1)" "unprognostic (5.06e-2)" "prognostic unfavorable (8.12e-4)" "unprognostic (4.24e-2)" "unprognostic (1.20e-2)" "unprognostic (1.47e-2)" "unprognostic (2.87e-2)" "unprognostic (1.00e-1)" "unprognostic (1.62e-3)" "unprognostic (1.83e-1)" "unprognostic (1.13e-1)" "unprognostic (6.16e-2)" "unprognostic (7.60e-3)" 6.8 7.0 3.6 6.3 4.2 3.9 10.5 3.9 4.7 8.1 3.0 6.4 4.2 7.0 6.9 6.6 6.4 6.1 6.0 3.3 4.7 15.7 11.4 5.9 9.9 4.4 4.2 9.9 4.7 9.6 3.1 6.8 4.5 6.5 5.8 5.2 4.7 9.2 6.5 6.4 5.0 6.6 4.0 7.4 6.0 3.7 3.9 15.6 10.1 8.6 10.6 6.2 5.3 4.6 6.1 7.0 14.7 18.9 15.7 18.8 9.6 6.7 9.4 9.5 9.4 13.6 5.8 21.8 43.9 8.6 10.8 5.4 10.8 5.4 13.6 20.6 11.5 13.1 4.8 25.8 13.4 23.2 14.8 8.4 13.4 9.6 14.4 14.5 17.3 17.3 27.7 3.9 13.6 6.7 26.6 15.1 7.9 14.3 9.4 21.5 17.0 33.8 17.6 5.4 13.5 7.2 6.8 10.3 21.3 26.4 12.9 11.8 7.2 15.1 10.7 8.9 5.9 16.5 37.3 19.7 6.2 17.9 15.9 16.2 9.4 18.3 11.8 12.3 15.7 18.9 15.3 15.2 16.6 17.7 15.2 15.9 2.3 19.6 6.7 7.2 15.2 11.8 3.6 4.2 3.9 4.7 3.3 4.7 4.4 4.2 4.5 4.0 3.9 4.6 18.1 12.8 6.9 0.0 14.6 6.0 8.3 6.8 8.6 7.0 7.1 9.9 7.3 0.0 7.9 25.8 2.1 12.5 15.6 5.9 35.2 9.9 7.5 11.5 12.4 10.7 1.8 7.2 0.0 8.7 9.2 10.6 7.7 19.5 16.5 14.5 0.0 0.0 7.8 6.7 0.0 6.9 2.0 0.0 6.1 7.8 9.6 11.0 3.6 0.0 10.7 13.2 12.3 0.0 0.0 10.1 3.9 12.4 7.3 8.4 6.7 41.8 7.7 8.4 0.0 12.4 9.3 5.8 14.4 8.9 7.5 8.2 12.7 22.5 6.6 7.5 BLVRB "FLR, SDR43U1" ENSG00000090013 "Biliverdin reductase B" P30043 19 40447765-40465764 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 625.2" "Cell type enhanced" "Detected in all" "Erythroid cells: 3131.8;Hofbauer cells: 1099.2;Proximal enterocytes: 864.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 465.2" "Group enriched" "Detected in all" 7 "dendritic cells: 343.3;monocytes: 465.2" "Cell line enhanced" "Detected in many" "A549: 506.6;K-562: 506.8;OE19: 451.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041698, HPA041937" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 370000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol "Nucleoplasm, Vesicles, Plasma membrane" "HPA041698: AB_10796781, HPA041937: AB_10794308" "unprognostic (1.86e-1)" "unprognostic (1.14e-2)" "unprognostic (4.23e-1)" "unprognostic (1.50e-1)" "unprognostic (2.08e-1)" "unprognostic (2.46e-1)" "unprognostic (9.92e-2)" "unprognostic (1.20e-2)" "unprognostic (8.56e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (3.90e-4)" "unprognostic (2.30e-1)" "unprognostic (2.70e-1)" "unprognostic (2.02e-1)" "unprognostic (5.11e-2)" "unprognostic (1.25e-1)" "unprognostic (3.92e-2)" 115.7 76.8 46.6 48.2 46.9 625.2 93.8 49.4 61.0 86.2 52.1 78.5 75.1 59.0 20.5 188.8 69.3 50.9 125.6 44.5 48.0 103.1 266.2 102.8 58.9 56.0 48.6 66.7 73.2 46.1 25.2 52.1 58.5 74.3 30.3 5.5 89.4 42.2 210.4 83.9 72.2 31.7 49.8 166.7 138.4 10.2 52.3 27.5 64.5 94.1 25.3 81.0 96.5 53.4 227.9 506.6 7.3 77.7 73.7 70.2 57.3 28.0 88.7 39.3 75.4 103.4 203.8 74.3 212.3 56.3 126.8 73.1 30.4 64.6 10.5 123.8 20.0 114.9 73.4 62.4 169.8 1.6 32.2 69.2 119.4 52.4 34.2 40.1 41.8 27.4 506.8 137.0 51.0 359.2 6.1 7.2 1.9 451.4 133.8 54.0 23.4 120.3 50.9 146.5 0.4 10.5 84.5 224.5 84.4 13.2 221.5 17.6 39.2 99.4 103.9 156.4 15.9 71.7 92.1 28.5 259.1 46.2 39.0 45.5 465.2 18.0 29.2 220.9 27.0 58.2 24.3 24.5 343.3 37.5 24.7 19.3 58.4 27.4 117.7 75.8 37.3 259.4 46.6 46.9 49.4 61.0 44.5 48.0 56.0 48.6 58.5 49.8 52.3 53.4 74.6 221.2 164.5 9.4 34.4 129.4 348.5 337.9 103.6 11.2 93.8 143.0 130.5 164.5 184.2 97.5 6.2 84.9 39.5 343.6 266.1 234.2 10.0 56.5 46.3 51.1 44.9 3131.8 5.2 267.3 94.7 112.5 280.3 83.1 43.1 31.0 57.1 680.8 1099.2 10.1 5.1 223.5 158.7 627.7 165.4 23.6 124.2 286.7 144.1 13.1 219.8 88.0 32.0 2.0 5.6 260.4 464.0 94.0 25.7 229.7 864.3 488.3 139.1 13.5 32.9 65.4 146.0 2.6 4.0 160.3 130.4 74.7 34.5 34.7 191.0 260.5 BMP2 BMP2A ENSG00000125845 "Bone morphogenetic protein 2" P12643 20 6767686-6780246 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 155.9;Basal keratinocytes: 167.1;Distal enterocytes: 125.6;Suprabasal keratinocytes: 119.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 31.6;HeLa: 19.6;hTERT-HME1: 17.8;RT4: 25.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA058610, CAB078457" Enhanced Vesicles "Secreted to blood" NA NA 24400 21000 "Cluster 19: Lung - Lung function" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB078457: AB_2532532, HPA058610: AB_2683777" "unprognostic (2.22e-2)" "unprognostic (9.32e-2)" "unprognostic (6.12e-2)" "unprognostic (3.56e-2)" "unprognostic (1.94e-2)" "unprognostic (2.48e-1)" "unprognostic (3.70e-3)" "unprognostic (3.12e-3)" "unprognostic (8.51e-2)" "unprognostic (8.46e-2)" "unprognostic (2.53e-3)" "unprognostic (5.39e-3)" "unprognostic (7.81e-2)" "unprognostic (3.76e-1)" "unprognostic (2.77e-1)" "unprognostic (3.01e-2)" "unprognostic (7.49e-2)" 18.6 1.6 1.2 4.0 1.5 1.6 6.0 1.3 1.6 5.2 0.9 15.1 6.6 5.2 0.6 5.5 3.8 16.1 4.0 1.8 1.4 3.9 5.8 18.8 1.9 1.9 2.2 2.8 9.2 3.2 2.3 11.5 2.1 1.9 13.6 1.3 2.1 1.2 2.2 10.6 9.7 2.6 1.5 12.4 20.7 0.5 2.1 0.4 18.9 2.7 1.8 17.2 6.4 2.2 0.1 0.3 0.0 0.0 0.5 0.2 0.0 0.8 3.4 0.0 0.0 31.6 0.1 0.0 0.5 1.1 0.0 10.5 6.2 2.7 0.0 0.0 5.5 0.0 19.6 0.1 1.5 0.0 0.8 0.2 9.2 0.0 17.8 4.0 6.3 0.0 0.0 0.0 0.2 0.0 0.0 6.0 0.8 3.7 0.8 6.2 0.1 0.4 2.3 25.0 1.1 1.6 7.3 0.0 0.0 5.5 0.0 6.5 1.5 1.8 2.7 0.0 0.9 0.3 0.9 0.0 3.0 1.7 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.2 1.5 1.3 1.6 1.8 1.4 1.9 2.2 2.1 1.5 2.1 2.2 9.4 80.1 155.9 0.3 1.1 167.1 45.1 11.0 70.0 0.4 1.4 2.2 4.7 42.9 10.5 1.8 0.0 0.1 3.8 125.6 0.0 23.3 0.3 1.7 34.8 24.1 11.3 0.0 1.1 9.8 0.2 20.2 33.6 3.0 8.8 1.9 41.4 3.4 3.6 0.0 3.5 23.8 0.0 2.9 16.8 0.2 5.9 2.9 8.8 2.8 0.6 6.2 0.0 8.5 1.4 33.5 60.3 0.0 1.3 47.5 28.3 2.1 0.8 0.2 19.7 36.5 48.8 0.0 0.3 43.1 119.3 0.1 2.1 4.3 48.2 43.3 BMP7 OP-1 ENSG00000101144 "Bone morphogenetic protein 7" P18075 20 57168753-57266641 "Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.8;choroid plexus: 43.8;thyroid gland: 45.9" "Cell type enhanced" "Detected in many" "Astrocytes: 74.1;Basal squamous epithelial cells: 51.8;Cytotrophoblasts: 137.4;Oligodendrocyte precursor cells: 74.4;Squamous epithelial cells: 44.2;Syncytiotrophoblasts: 56.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 172.1;MCF7: 202.3;OE19: 94.4;RPMI-8226: 77.8;SK-BR-3: 128.4;U-698: 237.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057757 Approved Nucleoplasm,Nucleoli,Vesicles "Secreted to blood" NA NA 248000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "Nucleoplasm, Nucleoli" "HPA057757: AB_2683518" "unprognostic (1.67e-1)" "unprognostic (9.72e-3)" "unprognostic (9.67e-2)" "prognostic unfavorable (2.91e-4)" "unprognostic (2.62e-1)" "unprognostic (1.60e-1)" "unprognostic (1.16e-1)" "unprognostic (1.01e-1)" "unprognostic (6.78e-2)" "unprognostic (4.63e-3)" "unprognostic (4.03e-2)" "unprognostic (1.09e-2)" "unprognostic (3.82e-2)" "unprognostic (4.30e-2)" "unprognostic (1.21e-1)" "unprognostic (5.42e-2)" "unprognostic (1.59e-1)" 1.5 6.5 33.1 1.9 34.6 0.0 1.3 37.2 27.9 8.5 43.8 2.9 2.2 1.2 17.2 23.9 9.5 0.4 13.8 35.6 28.5 6.3 0.0 1.6 1.0 36.2 36.3 0.2 0.5 0.0 2.7 25.7 34.7 5.9 1.7 5.3 3.9 9.2 0.3 22.5 1.9 0.3 32.8 0.6 3.6 0.7 39.7 3.8 45.9 0.0 2.1 6.8 13.0 42.8 0.3 0.7 23.4 5.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 20.0 6.8 172.1 41.3 0.0 8.7 48.3 5.2 0.0 0.0 0.4 17.2 0.1 0.0 0.0 0.0 0.0 5.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 202.3 0.0 0.1 12.3 94.4 0.0 0.1 0.1 77.8 0.0 0.2 0.4 17.8 5.5 128.4 0.5 15.2 0.9 0.4 0.4 0.1 10.9 0.0 0.1 0.2 0.3 237.6 0.1 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.1 34.6 37.2 27.9 35.6 28.5 36.2 36.3 34.7 32.8 39.7 42.8 0.6 6.4 2.2 74.1 0.4 13.8 13.4 12.9 51.8 4.7 0.9 4.6 15.1 0.0 4.2 1.8 0.0 137.4 0.1 0.2 0.0 0.0 5.3 1.7 2.4 1.2 2.4 0.0 0.9 0.0 21.0 13.5 2.0 2.5 21.6 0.1 0.0 0.0 11.0 1.7 4.7 1.5 6.1 0.0 1.9 4.9 0.3 0.4 3.6 2.8 0.1 38.4 0.0 74.4 8.7 0.0 0.3 0.4 2.5 6.6 0.2 2.2 1.9 2.4 0.0 1.3 0.8 1.8 3.4 44.2 9.7 56.9 0.9 0.7 1.5 18.1 BMP8A OP-2 ENSG00000183682 "Bone morphogenetic protein 8a" Q7Z5Y6 1 39491636-39529869 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 10 "thyroid gland: 91.6" "Group enriched" "Detected in some" 7 "Early spermatids: 42.2;Late spermatids: 164.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 7.0;HL-60: 5.8;U-2197: 22.2;U-266/70: 8.6;U-266/84: 7.9" HPA047254 Approved Vesicles "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA047254: " "unprognostic (9.62e-3)" "unprognostic (2.11e-2)" "unprognostic (7.79e-2)" "unprognostic (1.22e-1)" "unprognostic (1.37e-1)" "unprognostic (2.00e-1)" "unprognostic (2.91e-3)" "unprognostic (1.74e-1)" "unprognostic (1.21e-1)" "unprognostic (1.03e-1)" "unprognostic (1.54e-1)" "unprognostic (5.33e-3)" "unprognostic (2.95e-9)" "unprognostic (2.62e-2)" "unprognostic (1.49e-1)" "unprognostic (2.28e-3)" "unprognostic (2.55e-2)" 0.5 0.8 2.1 1.4 3.7 1.3 0.2 2.7 3.7 2.3 0.0 1.0 1.4 3.3 3.8 0.5 3.4 1.2 1.1 2.7 1.6 0.9 0.3 0.4 1.8 7.0 3.5 2.9 2.6 0.8 0.5 0.4 4.7 1.2 0.6 1.8 1.2 3.5 2.6 1.7 2.1 5.1 4.1 1.6 0.9 3.3 3.2 5.8 91.6 0.1 0.5 0.9 0.5 9.4 0.4 1.1 0.8 0.5 0.1 0.1 0.6 0.2 0.0 0.0 0.0 1.2 0.2 0.3 0.1 0.1 0.1 1.0 0.0 0.0 0.0 0.8 1.0 0.1 2.0 0.1 7.0 5.8 0.2 0.2 0.0 0.0 0.0 0.1 0.0 2.2 0.3 3.7 0.0 1.6 0.2 1.2 2.0 0.2 0.1 0.8 0.1 3.2 0.0 0.3 1.2 0.2 0.3 0.3 0.5 1.0 1.0 1.1 0.2 0.1 0.8 22.2 0.1 8.6 7.9 0.5 0.2 0.7 0.1 0.8 0.1 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.0 0.3 0.1 0.1 0.4 0.2 0.1 0.1 0.0 0.0 2.1 3.7 2.7 3.7 2.7 1.6 7.0 3.5 4.7 4.1 3.2 9.4 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.2 0.0 0.2 0.1 0.0 0.0 5.7 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 164.4 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.0 0.7 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 BMP8B "BMP8, OP-2" ENSG00000116985 "Bone morphogenetic protein 8b" P34820 1 39757182-39788865 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.4" "Group enriched" "Detected in many" 5 "Early spermatids: 72.1;Late spermatids: 106.5;Plasma cells: 38.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "THP-1: 120.5;U-266/70: 33.7;U-266/84: 52.5;WM-115: 56.7" HPA047254 Approved Vesicles "Secreted to blood" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA047254: " "unprognostic (1.53e-3)" "unprognostic (7.29e-2)" "unprognostic (2.18e-1)" "unprognostic (6.64e-3)" "unprognostic (8.79e-2)" "unprognostic (3.44e-2)" "unprognostic (7.27e-2)" "unprognostic (7.56e-2)" "unprognostic (1.88e-1)" "unprognostic (7.41e-2)" "unprognostic (2.68e-1)" "unprognostic (4.72e-4)" "unprognostic (1.79e-2)" "unprognostic (3.15e-1)" "unprognostic (9.67e-2)" "unprognostic (8.68e-3)" "unprognostic (4.82e-1)" 1.7 5.6 2.1 1.5 2.0 0.8 0.9 1.1 5.3 2.1 0.1 3.8 5.4 1.5 3.3 1.0 1.3 0.8 1.0 2.8 1.8 0.9 0.6 1.3 0.7 13.4 3.5 0.8 7.0 1.8 2.7 1.5 3.3 2.4 2.7 0.5 1.7 2.5 0.6 2.0 4.1 0.7 2.8 1.5 1.8 2.2 2.6 0.4 4.7 1.6 0.7 1.6 2.1 4.7 2.7 4.5 0.3 3.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.8 5.4 0.1 1.8 0.0 0.7 0.4 4.2 0.0 0.0 1.0 5.8 4.9 3.6 0.3 0.1 0.6 0.9 0.0 0.1 0.0 0.0 0.1 0.0 0.8 0.6 18.1 0.2 3.7 0.1 2.5 0.3 2.8 1.8 2.7 15.9 5.7 4.0 2.7 13.0 3.4 4.3 0.3 13.4 0.9 3.1 120.5 0.0 0.1 0.3 1.1 0.2 33.7 52.5 2.0 0.0 3.7 56.7 0.2 0.1 0.0 0.1 0.0 0.1 0.3 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 2.1 2.0 1.1 5.3 2.8 1.8 13.4 3.5 3.3 2.8 2.6 4.7 0.0 0.0 1.8 0.0 3.5 0.4 0.6 0.2 0.0 0.5 1.1 0.8 1.2 0.0 0.8 0.0 0.0 0.0 0.9 13.5 0.0 1.0 72.1 1.1 0.6 0.4 1.2 0.0 0.4 3.4 0.0 1.7 1.1 2.3 0.0 0.3 0.4 0.0 0.4 0.0 0.3 2.0 0.0 0.0 2.7 106.5 1.2 0.8 5.4 0.0 0.7 0.1 0.0 8.0 1.8 2.2 2.2 0.7 38.9 0.4 5.0 0.0 0.4 0.5 0.0 1.8 3.4 0.8 0.4 0.4 0.0 0.0 0.7 0.1 1.2 0.8 BORCS5 "LOH12CR1, LOH1CR12" ENSG00000165714 "BLOC-1 related complex subunit 5" Q969J3 12 12357078-12471233 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 42.6;T-cells: 39.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039509, HPA043627" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Plasma membrane" "HPA039509: AB_2676550, HPA043627: AB_2678588" "unprognostic (1.82e-1)" "unprognostic (2.87e-1)" "unprognostic (2.81e-1)" "unprognostic (2.41e-1)" "unprognostic (8.00e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (3.47e-4)" "unprognostic (6.78e-2)" "unprognostic (6.16e-2)" "unprognostic (2.79e-2)" "unprognostic (6.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.12e-3)" "unprognostic (1.50e-2)" "unprognostic (2.14e-1)" "unprognostic (1.72e-1)" "unprognostic (9.51e-2)" 6.3 8.1 5.1 2.5 7.1 6.2 6.1 5.2 6.4 6.6 2.3 5.8 1.7 5.8 5.8 8.0 5.7 2.4 7.1 4.1 5.8 5.9 8.5 6.5 2.9 5.6 5.4 4.9 7.2 3.8 7.1 2.7 6.2 5.9 2.2 2.8 5.4 1.9 8.4 8.7 4.7 3.0 4.7 6.2 5.9 9.1 5.4 3.1 4.6 3.3 3.9 5.6 6.8 8.2 3.9 4.1 2.9 3.0 6.4 8.7 3.3 3.4 3.9 4.1 5.1 10.0 3.9 4.9 2.0 5.5 2.9 2.7 5.0 4.9 4.4 14.0 4.5 2.7 3.9 5.7 6.1 2.9 3.8 4.9 3.5 5.6 6.5 6.5 4.9 6.1 3.8 6.6 5.4 8.4 4.2 3.0 9.0 4.1 2.6 3.4 4.1 5.3 5.1 2.6 3.6 4.1 3.3 3.0 7.5 9.6 2.3 3.1 4.1 2.7 6.1 3.5 3.1 3.4 3.2 11.1 5.8 4.4 4.6 2.8 6.1 9.5 10.1 10.3 11.9 7.7 11.5 11.2 7.3 5.9 7.6 7.7 6.7 12.4 6.7 5.1 14.2 7.0 5.1 7.1 5.2 6.4 4.1 5.8 5.6 5.4 6.2 4.7 5.4 8.2 11.1 9.6 2.3 0.0 37.9 0.0 11.9 0.0 10.8 16.9 10.5 8.4 0.0 10.0 2.5 7.3 12.5 9.2 42.6 2.2 9.8 9.5 5.6 8.8 9.0 6.7 4.9 5.9 0.0 12.4 11.7 8.3 19.9 8.9 2.5 7.4 6.1 5.1 14.5 13.5 0.0 3.8 0.0 11.0 0.0 3.9 5.3 26.3 0.0 0.0 19.0 12.5 14.4 0.0 0.0 9.5 3.5 7.2 33.0 9.1 10.3 14.1 2.9 16.6 26.3 8.3 8.1 23.4 8.6 14.6 0.0 14.5 39.5 7.5 4.6 8.3 BORCS6 "C17orf59, FLJ20014" ENSG00000196544 "BLOC-1 related complex subunit 6" Q96GS4 17 8188345-8190180 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 45.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045415, HPA060791" Uncertain Approved "Golgi apparatus,Vesicles" NA NA 11000 "Cluster 2: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 51: Myeloid cells - Hemostasis" "Golgi apparatus, Vesicles" "HPA045415: AB_10964575, HPA060791: AB_2684367" "unprognostic (2.11e-1)" "unprognostic (7.22e-3)" "unprognostic (3.25e-2)" "prognostic favorable (2.78e-4)" "unprognostic (3.84e-2)" "unprognostic (9.91e-3)" "unprognostic (7.51e-2)" "unprognostic (1.15e-1)" "unprognostic (1.61e-2)" "unprognostic (6.93e-2)" "prognostic favorable (2.60e-4)" "unprognostic (2.69e-1)" "unprognostic (2.22e-3)" "unprognostic (2.18e-2)" "unprognostic (4.38e-2)" "unprognostic (3.28e-1)" "unprognostic (3.10e-2)" 6.4 8.4 9.8 5.0 9.9 4.2 5.7 10.1 10.4 5.7 7.9 8.3 7.2 6.6 3.7 10.9 5.2 2.3 10.1 9.1 8.9 7.7 8.0 5.4 6.7 11.8 10.0 4.1 14.4 6.1 4.7 4.0 10.7 6.2 2.7 3.1 6.2 4.9 15.0 12.5 8.6 2.8 9.8 11.6 8.2 5.5 9.9 5.3 5.7 6.0 4.9 7.1 6.5 10.8 6.3 7.5 2.5 5.1 5.3 3.9 10.0 4.6 5.1 4.4 4.7 4.2 4.2 5.9 9.9 3.7 4.2 9.2 3.9 5.4 1.5 17.8 16.3 4.5 7.0 6.5 6.0 2.7 9.5 4.0 5.7 4.0 4.6 3.9 7.2 8.6 5.1 12.0 2.7 6.7 9.0 7.7 1.8 4.0 8.3 10.6 3.2 8.9 6.1 3.5 3.0 6.9 4.7 3.5 4.2 2.5 5.1 4.2 5.8 2.7 2.4 4.2 5.0 18.0 8.8 2.7 3.9 9.5 3.3 46.4 18.6 50.7 27.8 18.7 22.7 23.5 23.4 29.6 20.9 23.3 22.0 24.9 17.0 28.5 23.1 18.3 23.5 21.4 9.8 9.9 10.1 10.4 9.1 8.9 11.8 10.0 10.7 9.8 9.9 10.8 13.5 9.6 6.4 0.0 21.6 0.0 2.6 0.0 14.2 23.1 9.0 9.5 0.0 11.5 0.6 5.5 6.2 20.4 22.3 12.2 7.9 9.7 2.4 5.6 3.8 10.9 1.2 11.4 0.0 17.7 12.0 4.4 4.1 5.7 3.8 5.2 12.5 9.4 20.9 18.5 0.0 8.6 0.0 21.1 0.0 3.2 5.9 21.5 0.0 0.0 25.6 23.8 45.3 0.0 0.0 11.3 18.3 6.8 18.5 3.5 29.8 10.3 0.0 19.7 32.9 4.3 6.7 9.0 1.3 17.3 0.0 6.2 18.7 9.4 7.5 1.5 BORCS8 MEF2BNB ENSG00000254901 "BLOC-1 related complex subunit 8" Q96FH0 19 19176903-19192591 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045700 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 7: Non-specific - Mitochondria" Vesicles Nucleoplasm "HPA045700: AB_10968570" "unprognostic (4.23e-3)" "unprognostic (1.61e-2)" "unprognostic (2.75e-1)" "unprognostic (3.58e-2)" "unprognostic (2.28e-1)" "unprognostic (3.01e-2)" "unprognostic (5.51e-2)" "unprognostic (5.81e-3)" "unprognostic (1.78e-2)" "unprognostic (6.82e-2)" "prognostic favorable (4.05e-5)" "unprognostic (6.20e-2)" "unprognostic (1.76e-1)" "unprognostic (1.22e-1)" "unprognostic (3.16e-1)" "unprognostic (1.38e-2)" "unprognostic (3.00e-2)" 12.7 12.4 27.2 11.9 27.1 15.9 8.4 27.1 34.7 6.1 25.3 9.7 11.0 6.5 6.4 11.7 10.8 7.6 17.4 27.2 29.7 13.4 10.7 10.5 12.5 28.0 27.7 5.3 11.0 15.9 20.3 7.6 28.8 10.0 8.7 5.5 9.9 7.9 14.3 8.7 8.1 8.8 25.4 10.1 9.8 8.6 27.2 12.2 12.5 18.0 8.7 10.8 6.3 28.4 21.9 15.4 13.5 14.4 17.8 8.7 22.5 22.4 16.3 25.9 25.7 17.9 26.1 12.9 36.6 22.1 19.1 12.9 12.9 28.5 9.9 12.6 18.9 11.1 23.0 18.0 14.8 17.4 17.8 13.6 15.0 23.2 9.2 11.0 29.7 19.0 26.1 21.1 28.5 38.6 25.7 14.5 9.8 23.3 18.7 10.3 9.9 18.7 27.3 17.1 26.2 14.5 22.4 17.0 15.9 10.0 20.8 17.3 17.0 14.1 14.9 32.5 34.3 15.7 15.3 15.3 16.8 14.0 27.8 45.3 32.4 57.2 14.5 44.9 12.5 27.0 15.4 14.6 22.2 19.6 12.9 13.2 79.9 14.9 45.9 30.1 19.7 20.0 27.2 27.1 27.1 34.7 27.2 29.7 28.0 27.7 28.8 25.4 27.2 28.4 16.6 12.8 21.6 0.0 13.6 0.0 15.4 0.0 5.2 17.0 19.6 18.5 0.0 25.8 7.4 14.7 10.4 31.8 22.5 11.6 43.0 38.0 5.0 25.4 12.1 12.3 10.9 10.8 0.0 32.7 34.9 11.1 13.3 15.7 10.1 11.6 12.1 16.6 41.0 18.5 0.0 9.3 0.0 23.4 0.0 5.2 7.8 24.0 0.0 0.0 37.1 13.2 15.5 0.0 0.0 42.4 9.5 6.8 15.3 14.7 25.6 40.8 13.1 18.3 0.0 11.6 15.0 33.8 23.9 7.4 0.0 39.5 14.0 18.6 9.5 17.2 BPIFB2 "BPIL1, C20orf184, dJ726C3.2, LPLUNC2" ENSG00000078898 "BPI fold containing family B member 2" Q8N4F0 20 33007704-33023703 "Plasma proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "salivary gland: 2294.3" "Group enriched" "Detected in some" 4 "Breast glandular cells: 6.1;Breast myoepithelial cells: 9.1;Early spermatids: 4.8;Late spermatids: 9.3;Prostatic glandular cells: 7.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 20.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 582 "Hep G2: 232.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049491, HPA060121" Enhanced Approved Vesicles "Secreted in other tissues" NA NA 36000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 35: Glandular cells - Unknown function" Vesicles "HPA049491: AB_2680792, HPA060121: AB_2684207" "unprognostic (1.94e-1)" "prognostic favorable (1.97e-5)" "unprognostic (2.24e-4)" "unprognostic (9.48e-2)" "unprognostic (9.81e-2)" "unprognostic (2.02e-3)" "unprognostic (1.72e-2)" "unprognostic (2.71e-1)" "unprognostic (9.28e-2)" "unprognostic (5.35e-1)" "unprognostic (8.19e-2)" 0.4 0.6 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.7 0.0 0.1 0.0 0.0 0.0 99.8 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 1.8 0.0 0.0 2294.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 232.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.1 9.1 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 7.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 BRAF BRAF1 ENSG00000157764 "B-Raf proto-oncogene, serine/threonine kinase" P15056 7 140719327-140924929 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 252.3;Inhibitory neurons: 242.4;Oligodendrocyte precursor cells: 206.1;Oligodendrocytes: 202.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001328, CAB004552, HPA071048" Approved Approved Vesicles,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 29: U-266 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Vesicles Cytosol "CAB004552: AB_626760, HPA001328: AB_1078296, HPA071048: AB_2686336" "unprognostic (2.98e-3)" "unprognostic (5.66e-2)" "unprognostic (2.20e-2)" "unprognostic (2.66e-3)" "unprognostic (2.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.07e-2)" "unprognostic (4.23e-2)" "unprognostic (4.07e-2)" "unprognostic (1.58e-2)" "unprognostic (6.53e-2)" "unprognostic (1.91e-2)" "unprognostic (3.79e-3)" "unprognostic (2.08e-1)" "unprognostic (1.76e-1)" "unprognostic (8.01e-2)" "unprognostic (5.46e-2)" 8.8 5.8 6.3 5.6 7.7 15.9 8.8 12.5 8.7 8.2 5.4 8.6 4.7 8.3 8.3 7.5 8.0 5.8 7.6 8.3 6.7 7.6 6.6 9.9 6.9 4.0 3.6 9.8 8.3 11.5 9.0 7.2 4.6 8.2 5.4 17.0 7.2 5.9 8.6 10.4 6.9 6.0 3.1 6.7 7.8 13.7 5.2 8.7 10.2 8.4 6.4 9.9 8.5 6.7 6.3 5.2 7.7 9.4 9.1 11.8 12.3 6.8 7.5 5.4 7.6 5.7 6.7 10.8 5.0 7.3 8.4 3.4 6.8 5.5 10.0 9.8 5.4 7.1 5.1 5.2 7.6 11.7 6.8 7.9 6.1 6.0 12.0 8.2 6.6 7.7 11.3 19.1 9.8 3.3 15.6 12.0 6.9 6.2 3.1 10.1 6.5 8.9 5.3 11.9 8.9 7.3 7.9 4.9 7.3 7.5 4.5 7.8 9.7 5.9 4.3 12.9 5.5 21.6 12.9 16.7 9.7 11.3 6.6 1.9 1.0 4.1 1.5 0.9 1.0 1.3 1.5 1.2 0.8 1.1 2.6 1.3 2.0 3.5 1.3 1.0 1.5 0.6 6.3 7.7 12.5 8.7 8.3 6.7 4.0 3.6 4.6 3.1 5.2 6.7 43.4 22.4 45.7 151.1 58.4 21.5 24.6 6.0 23.3 29.7 31.2 21.2 19.8 10.0 18.7 25.8 35.5 15.7 73.5 8.8 7.9 14.3 68.6 50.6 37.4 23.4 19.2 14.9 252.3 9.8 12.9 22.0 21.9 69.2 24.7 45.5 9.3 9.6 9.4 25.2 242.4 9.8 8.2 13.6 37.1 36.5 16.4 30.1 16.0 126.5 14.6 11.3 15.5 206.1 202.6 15.4 8.1 10.1 48.7 23.8 8.0 13.4 20.0 33.0 6.6 24.1 24.7 43.8 26.0 14.5 24.0 75.5 41.4 30.9 8.7 33.4 BSG "CD147, EMMPRIN, EMPRIN, OK" ENSG00000172270 "Basigin (Ok blood group)" P35613 19 571277-583494 "Blood group antigen proteins, CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Host-virus interaction" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1535.0" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1408.0;Syncytiotrophoblasts: 1654.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002427, HPA036048, HPA074870" Enhanced Approved Vesicles NA NA 340000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB002427: AB_563501, HPA036048: AB_2674917, HPA074870: AB_2686719" "unprognostic (1.88e-1)" "unprognostic (4.85e-2)" "unprognostic (9.53e-3)" "prognostic favorable (2.59e-4)" "unprognostic (3.34e-1)" "unprognostic (1.38e-2)" "prognostic unfavorable (5.48e-6)" "unprognostic (1.54e-3)" "unprognostic (1.55e-1)" "unprognostic (9.46e-2)" "unprognostic (4.48e-3)" "unprognostic (2.61e-2)" "prognostic favorable (1.95e-6)" "unprognostic (1.22e-1)" "unprognostic (1.03e-1)" "unprognostic (7.30e-2)" "unprognostic (3.22e-1)" 378.6 518.8 652.6 154.5 615.4 431.3 313.8 575.6 847.5 320.6 975.8 543.5 231.3 413.3 259.5 245.1 323.1 176.2 1535.0 629.0 606.0 469.7 186.0 253.6 101.9 578.5 611.2 300.7 301.6 255.3 331.2 320.2 599.8 228.8 155.9 189.6 274.8 194.4 472.3 226.6 239.7 164.1 551.0 200.0 455.8 486.0 724.3 92.8 302.1 292.2 74.2 366.9 233.0 581.2 622.6 739.3 339.5 852.3 975.0 426.0 800.4 499.2 507.6 506.1 437.9 607.1 569.4 208.4 564.3 383.5 148.7 967.8 341.0 575.0 129.6 468.1 840.3 150.0 545.5 812.3 683.6 361.6 679.0 455.5 578.5 302.4 304.5 613.1 383.3 198.3 722.9 992.5 298.6 1015.8 261.6 706.6 901.9 353.7 408.3 522.8 301.2 745.2 655.9 412.1 561.0 539.1 984.4 408.1 769.7 257.9 432.3 1118.9 478.7 557.5 353.4 940.1 751.5 639.7 701.8 201.1 1066.9 510.2 712.8 189.0 324.7 348.9 226.4 245.9 200.5 115.0 150.7 218.4 209.6 93.2 114.0 144.7 474.8 173.5 284.2 235.2 192.0 434.0 652.6 615.4 575.6 847.5 629.0 606.0 578.5 611.2 599.8 551.0 724.3 581.2 313.5 22.4 31.5 75.1 101.5 208.6 176.8 668.0 91.0 157.7 202.8 187.6 80.6 128.7 253.4 286.9 204.3 1408.0 156.5 1140.1 146.8 580.9 261.6 156.6 296.6 246.7 255.1 1091.4 35.4 371.4 1095.5 279.8 192.1 190.1 116.2 181.1 132.1 96.9 416.7 139.7 31.4 337.2 510.6 137.8 179.6 600.2 300.4 139.8 506.9 122.7 264.5 495.5 221.4 20.6 30.7 458.0 929.1 336.7 192.4 172.8 450.7 306.7 178.8 269.2 203.8 74.3 235.6 347.9 604.4 127.7 156.7 1654.9 130.9 223.5 478.2 181.4 BST2 "CD317, tetherin" ENSG00000130303 "Bone marrow stromal cell antigen 2" Q10589 19 17402939-17405630 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Antiviral defense, B-cell activation, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 694.2" "Cell type enhanced" "Detected in many" "Adipocytes: 1193.2;Hepatic stellate cells: 455.8;Theca cells: 490.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 615.0;Karpas-707: 603.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA017060, HPA073472" Enhanced Supported "Golgi apparatus,Vesicles" NA NA 260000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 72: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Vesicles" "HPA017060: AB_1845467, HPA073472: " "prognostic favorable (6.69e-4)" "unprognostic (1.75e-1)" "unprognostic (8.42e-3)" "unprognostic (8.93e-3)" "unprognostic (4.87e-2)" "unprognostic (2.25e-1)" "unprognostic (2.26e-1)" "unprognostic (1.07e-1)" "unprognostic (3.25e-1)" "unprognostic (6.46e-2)" "unprognostic (6.56e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.56e-9)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.22e-4)" "unprognostic (1.08e-1)" "unprognostic (2.46e-2)" 226.0 509.8 86.7 95.6 87.6 103.7 152.9 84.0 125.7 93.4 81.7 94.1 47.4 58.7 59.5 40.3 248.0 109.4 111.2 85.1 84.5 160.1 227.8 141.4 128.0 101.5 85.9 694.2 26.3 13.8 56.8 203.0 88.4 88.6 33.3 2.0 77.7 105.2 46.1 24.8 109.1 76.0 97.0 238.5 84.1 35.4 91.1 123.5 54.0 50.8 65.8 82.9 88.6 90.8 327.0 0.5 0.9 145.6 0.0 1.0 49.6 1.3 24.9 459.5 615.0 150.5 286.1 252.2 338.2 197.6 14.6 1.3 212.9 23.9 14.3 279.1 1.8 3.6 525.7 149.8 256.7 120.1 304.7 1.3 0.0 153.0 0.1 4.4 119.0 6.0 146.3 603.4 0.0 89.5 57.7 208.6 158.0 0.1 407.9 105.5 0.8 530.7 110.1 1.5 0.6 1.4 325.5 12.3 410.5 12.3 243.1 166.3 1.5 1.9 11.4 0.5 3.3 308.3 439.3 168.0 1.3 470.8 2.2 229.7 345.3 125.3 171.4 385.5 163.0 115.2 143.2 160.0 283.8 146.5 114.8 132.6 113.3 353.2 359.3 421.7 143.3 367.9 86.7 87.6 84.0 125.7 85.1 84.5 101.5 85.9 88.4 97.0 91.1 90.8 1193.2 57.7 13.6 4.9 90.7 33.1 19.6 255.7 48.9 0.2 86.2 168.5 7.0 50.1 68.5 49.7 0.0 7.8 184.2 1.5 37.2 18.7 10.7 27.8 11.2 420.2 1.2 74.0 0.0 1.2 61.5 152.4 14.8 50.1 227.8 260.9 455.8 211.1 388.9 0.0 0.0 2.8 28.5 189.4 187.6 12.0 346.7 220.4 74.7 32.8 214.5 1.3 211.2 0.5 0.3 3.3 4.8 419.4 192.8 10.3 3.7 1.3 27.4 2.1 164.3 30.7 146.3 1.3 1.2 15.5 26.1 13.1 135.8 490.6 5.0 28.6 BTAF1 "MOT1, TAF-172, TAF(II)170, TAF172, TAFII170" ENSG00000095564 "B-TFIID TATA-box binding protein associated factor 1" O14981 10 91923770-92030325 "Plasma proteins, Predicted intracellular proteins" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 91.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070682 Supported Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Vesicles "HPA070682: AB_2686294" "unprognostic (2.41e-1)" "unprognostic (1.29e-1)" "unprognostic (5.39e-2)" "unprognostic (1.20e-1)" "unprognostic (3.92e-1)" "prognostic favorable (5.07e-4)" "unprognostic (2.72e-1)" "unprognostic (9.28e-2)" "unprognostic (1.16e-1)" "unprognostic (7.34e-2)" "unprognostic (9.70e-3)" "unprognostic (4.27e-2)" "prognostic unfavorable (4.04e-5)" "unprognostic (6.45e-2)" "unprognostic (1.10e-1)" "unprognostic (4.79e-2)" "unprognostic (1.98e-1)" 20.4 13.2 5.2 20.1 7.3 32.1 19.2 8.5 8.6 18.4 5.9 20.4 16.2 20.7 21.1 17.2 23.4 15.2 14.4 6.1 5.5 11.8 15.4 19.1 32.0 6.1 5.3 25.4 18.1 14.7 13.3 13.7 6.0 16.8 15.9 34.3 19.2 12.7 14.8 50.4 22.0 14.0 5.9 22.0 18.4 17.9 5.8 21.7 17.3 9.2 25.5 20.1 19.9 10.4 28.9 13.8 31.7 38.7 16.5 25.8 15.8 16.5 19.6 16.0 23.7 19.1 17.2 30.8 10.3 16.3 9.9 30.4 21.5 14.6 23.8 21.2 23.2 21.9 35.7 20.0 16.8 33.3 22.0 18.4 18.5 24.3 35.1 34.3 15.6 25.9 18.2 34.5 16.6 12.6 25.8 21.0 14.4 8.3 10.8 20.6 19.7 14.5 14.9 17.5 12.2 14.3 15.8 8.0 20.3 20.8 16.2 21.9 16.9 14.3 11.4 19.5 23.7 39.7 19.6 24.9 22.4 30.1 3.8 4.4 2.7 1.5 2.5 1.9 2.2 2.5 1.9 1.8 2.1 3.1 2.3 1.8 1.9 2.2 3.6 4.9 1.6 1.4 5.2 7.3 8.5 8.6 6.1 5.5 6.1 5.3 6.0 5.9 5.8 10.4 18.3 19.2 31.5 58.4 29.5 21.7 12.1 7.3 21.6 26.7 16.2 11.9 13.6 7.2 14.6 20.2 45.9 6.6 34.8 7.9 1.9 6.8 12.9 33.3 28.0 15.6 16.2 13.9 78.5 6.6 9.8 17.3 35.2 46.6 24.1 22.4 8.9 8.7 7.1 18.5 66.4 7.1 6.1 9.7 19.8 5.1 11.8 27.1 5.4 67.5 16.4 13.9 14.4 68.3 91.5 6.7 6.3 11.7 52.1 15.7 9.6 3.3 24.9 35.5 6.6 25.7 22.8 24.7 12.2 20.4 29.8 14.6 24.7 11.4 9.3 16.4 BTBD18 ENSG00000233436 "BTB domain containing 18" B2RXH4 11 57743514-57751781 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 3.1;testis: 2.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.7;Cone photoreceptor cells: 4.2;Rod photoreceptor cells: 1.6;Spermatocytes: 5.5;Spermatogonia: 3.9" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 3.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA049325 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 21: Non-specific - Transcription" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Plasma membrane" Vesicles "HPA049325: AB_2680713" "unprognostic (6.68e-2)" "unprognostic (3.13e-2)" "unprognostic (3.43e-1)" "unprognostic (4.81e-2)" "unprognostic (1.75e-1)" "unprognostic (2.47e-2)" "unprognostic (8.69e-3)" "unprognostic (4.84e-3)" "unprognostic (1.77e-1)" "unprognostic (2.96e-1)" "unprognostic (7.17e-3)" "unprognostic (5.95e-3)" "unprognostic (1.42e-2)" "unprognostic (2.34e-2)" "unprognostic (3.15e-1)" "unprognostic (3.34e-1)" "unprognostic (2.88e-1)" 0.0 0.0 0.1 0.0 0.3 0.4 0.0 3.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.2 0.1 0.0 0.4 0.4 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.3 3.1 0.9 0.2 0.0 0.2 0.1 0.2 0.0 0.1 0.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.3 0.0 0.0 0.0 4.2 0.0 0.1 0.0 0.0 0.0 0.2 0.7 0.4 0.1 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.2 0.0 1.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.3 0.0 5.5 3.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 BTBD3 "dJ742J24.1, KIAA0952" ENSG00000132640 "BTB domain containing 3" Q9Y2F9 20 11890723-11926609 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 80.9" "Cell type enhanced" "Detected in all" "Endometrial stromal cells: 223.0;Oligodendrocytes: 254.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 241.1;HeLa: 186.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041424, HPA042048" Uncertain Supported Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA041424: AB_10794667, HPA042048: AB_10796469" "unprognostic (3.93e-2)" "unprognostic (2.25e-1)" "unprognostic (1.32e-1)" "unprognostic (3.56e-3)" "unprognostic (4.24e-3)" "unprognostic (8.45e-2)" "prognostic unfavorable (2.51e-5)" "prognostic unfavorable (6.94e-4)" "unprognostic (4.87e-2)" "unprognostic (2.95e-1)" "unprognostic (1.07e-2)" "unprognostic (7.05e-2)" "unprognostic (6.66e-2)" "unprognostic (7.68e-3)" "unprognostic (1.67e-1)" "unprognostic (6.29e-2)" "unprognostic (1.37e-2)" 11.2 22.1 20.6 7.1 34.2 12.2 12.7 66.2 80.9 16.9 12.3 21.4 10.7 18.7 7.9 9.9 15.4 13.4 13.9 79.6 30.9 11.6 7.7 12.2 4.1 30.5 24.7 11.5 13.7 11.2 8.9 42.0 23.1 15.1 17.5 42.5 13.9 10.6 15.9 20.7 10.9 16.5 24.2 7.8 27.3 14.7 23.7 10.8 11.5 13.2 3.1 18.4 10.1 64.7 7.0 19.5 52.1 241.1 10.6 11.3 14.0 21.9 14.0 24.3 15.5 11.2 10.7 2.0 18.1 31.7 9.6 18.1 27.2 15.4 39.1 0.1 24.1 7.1 186.9 23.9 11.1 11.6 4.2 20.2 18.8 21.8 17.5 13.4 13.8 12.0 12.7 18.8 24.3 5.1 14.0 10.7 25.0 29.0 5.5 18.4 10.4 7.0 22.2 34.0 22.7 40.0 60.8 24.6 53.3 27.9 14.4 11.5 10.7 13.2 33.6 12.4 24.6 6.9 9.9 0.3 8.6 3.2 87.6 0.0 1.2 0.1 0.0 1.7 0.0 0.0 0.0 0.0 1.4 0.1 0.3 0.0 0.3 0.7 3.5 1.0 0.0 0.6 20.6 34.2 66.2 80.9 79.6 30.9 30.5 24.7 23.1 24.2 23.7 64.7 17.4 16.0 8.4 24.5 2.8 16.6 10.8 8.0 18.8 15.3 15.2 11.9 16.5 10.0 8.3 5.5 79.2 23.3 1.0 41.0 3.9 9.8 8.3 51.3 223.0 25.0 20.9 4.6 46.9 8.3 4.0 15.6 28.5 55.8 2.5 9.4 33.5 8.5 8.5 65.6 38.0 9.4 10.2 4.8 13.4 13.6 16.4 6.5 14.2 39.4 3.2 17.7 1.0 61.9 254.9 9.7 25.9 8.6 2.7 13.2 11.4 6.6 24.1 56.9 6.6 19.9 18.6 10.0 16.1 11.7 17.2 21.8 1.8 42.0 13.3 11.3 BTG2 "APRO1, MGC126063, MGC126064, PC3, TIS21" ENSG00000159388 "BTG anti-proliferation factor 2" P78543 1 203305491-203309602 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enteroendocrine cells: 965.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 161.8;HMC-1: 160.8;RT4: 131.3;U-266/70: 259.8;U-266/84: 141.2" "Low region specificity" "Detected in all" HPA002355 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 50: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles Nucleoplasm "HPA002355: AB_1078304" "prognostic favorable (8.53e-4)" "unprognostic (1.54e-1)" "unprognostic (4.63e-2)" "unprognostic (4.81e-3)" "unprognostic (5.91e-2)" "unprognostic (1.46e-1)" "unprognostic (2.47e-1)" "unprognostic (7.87e-3)" "unprognostic (4.72e-1)" "unprognostic (1.71e-1)" "unprognostic (1.61e-1)" "unprognostic (1.18e-2)" "unprognostic (4.46e-2)" "unprognostic (6.22e-2)" "unprognostic (4.34e-1)" "unprognostic (1.17e-1)" "unprognostic (2.86e-3)" 274.5 244.6 38.3 124.3 40.7 309.3 118.8 58.4 45.0 101.7 36.7 231.5 88.5 91.9 41.5 313.4 355.0 157.8 256.3 35.1 49.0 132.2 20.8 105.0 122.0 61.8 42.1 554.9 488.9 37.4 209.2 106.7 43.6 265.9 205.7 152.6 75.1 182.9 210.7 134.4 111.1 213.7 49.3 107.1 244.5 10.2 42.4 334.6 201.2 287.1 132.3 279.9 79.1 42.1 4.3 6.1 10.9 4.5 13.4 9.8 92.9 11.2 21.4 2.8 10.5 8.8 1.6 161.8 7.8 3.5 1.8 69.5 39.6 42.6 5.2 10.8 20.3 84.5 12.3 18.4 29.5 0.4 160.8 10.1 76.7 10.3 18.7 9.5 57.6 8.2 40.6 106.9 28.1 3.6 18.1 5.4 4.9 1.7 1.2 11.4 36.5 84.3 5.3 131.3 1.9 11.3 8.6 3.6 1.4 80.0 9.0 10.1 14.3 0.3 18.2 2.9 0.6 259.8 141.2 103.4 2.2 4.1 6.3 8.4 19.7 23.1 10.0 27.1 14.8 29.9 10.9 10.2 11.5 29.0 17.5 12.6 77.1 12.7 35.6 38.6 11.2 19.7 38.3 40.7 58.4 45.0 35.1 49.0 61.8 42.1 43.6 49.3 42.4 42.1 555.8 157.0 241.8 6.5 330.1 230.2 464.4 311.4 548.7 25.4 355.1 276.7 274.8 48.6 128.5 187.6 29.2 50.0 343.9 345.8 15.6 113.2 1.4 336.7 211.7 196.4 965.1 127.6 2.9 163.7 16.6 352.8 562.2 643.2 369.3 40.6 148.2 6.5 120.1 3.3 2.0 617.1 264.5 98.8 183.6 3.1 72.7 227.0 120.9 25.3 47.5 478.8 58.7 4.5 10.4 55.9 399.9 55.3 725.2 230.1 397.5 13.9 88.5 38.9 124.9 537.5 305.0 1.8 1.7 343.8 447.9 138.0 300.8 278.6 360.7 211.8 BTN3A1 "BT3.1, BTF5, BTN3.1, CD277" ENSG00000026950 "Butyrophilin subfamily 3 member A1" O00481 6 26402237-26415208 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 59.1;NK-cells: 73.2;Plasma cells: 47.6;T-cells: 50.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" HPA012565 Approved Uncertain Vesicles NA NA "Cluster 34: Basophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA012565: AB_1845494" "unprognostic (2.82e-2)" "unprognostic (6.43e-2)" "unprognostic (1.45e-3)" "unprognostic (4.72e-3)" "unprognostic (1.41e-2)" "unprognostic (1.42e-1)" "unprognostic (3.10e-2)" "unprognostic (9.31e-2)" "unprognostic (9.81e-2)" "unprognostic (8.60e-3)" "unprognostic (1.19e-1)" "unprognostic (2.41e-1)" "prognostic unfavorable (4.15e-5)" "unprognostic (2.45e-1)" "unprognostic (5.02e-2)" "unprognostic (3.26e-2)" "prognostic favorable (4.81e-4)" 19.2 20.7 10.2 44.8 11.1 29.6 20.1 9.8 10.5 21.2 10.3 24.8 28.5 28.0 16.0 11.9 22.5 30.5 12.1 9.1 12.1 12.8 18.9 41.4 63.4 16.4 10.9 35.1 13.1 13.1 13.7 19.2 12.5 16.5 28.8 3.6 23.9 13.5 12.8 24.9 35.1 21.3 12.2 84.0 31.3 5.0 11.4 33.1 11.5 14.5 52.6 20.0 17.4 12.0 7.4 6.2 9.3 9.5 25.9 27.5 1.2 6.2 24.1 13.5 39.4 0.3 16.7 19.7 20.4 11.2 20.9 5.1 3.0 9.7 8.2 19.5 6.4 10.4 8.5 4.7 11.8 9.5 9.3 15.0 5.6 11.8 5.4 20.4 19.3 31.0 2.5 25.3 5.5 0.6 17.6 6.6 1.0 3.3 2.1 24.2 4.0 45.2 8.3 9.4 4.9 9.8 3.4 7.1 13.5 1.4 6.5 4.0 4.8 10.3 2.6 3.1 5.9 41.8 45.9 7.3 15.6 21.4 8.4 53.8 11.1 28.8 44.7 11.7 40.4 18.8 27.8 42.3 9.1 10.5 24.1 32.0 23.9 40.5 12.9 4.3 36.0 28.0 10.2 11.1 9.8 10.5 9.1 12.1 16.4 10.9 12.5 12.2 11.4 12.0 24.8 16.0 6.5 0.0 27.1 4.2 3.9 3.5 2.2 4.3 8.6 8.1 4.2 11.5 8.5 5.5 0.0 5.5 59.1 8.2 0.0 7.4 0.1 5.5 10.4 18.0 4.8 13.3 0.0 3.2 4.3 9.9 9.2 10.3 25.9 14.0 11.7 3.9 7.2 0.0 0.0 17.3 2.0 19.2 6.1 0.8 3.7 15.4 1.8 0.0 13.7 1.9 73.2 0.0 0.0 2.2 6.3 2.6 47.6 5.4 15.9 1.3 6.7 0.4 0.0 6.7 5.5 0.0 0.1 3.6 3.3 1.5 50.1 8.4 7.4 5.0 BTNL9 "BTN8, FLJ32535" ENSG00000165810 "Butyrophilin like 9" Q6UXG8 5 181040225-181061521 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 250.8;breast: 200.0" "Cell type enriched" "Detected in many" 6 "Adipocytes: 900.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "OE19: 9.9;U-698: 37.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA043429 Approved "Nuclear membrane,Vesicles" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear membrane" Vesicles "HPA043429: AB_10961264" "unprognostic (2.69e-1)" "unprognostic (1.44e-2)" "unprognostic (5.76e-2)" "prognostic unfavorable (7.51e-4)" "unprognostic (2.07e-1)" "unprognostic (1.43e-1)" "prognostic favorable (1.55e-9)" "unprognostic (2.15e-2)" "unprognostic (8.51e-2)" "unprognostic (1.78e-1)" "unprognostic (1.93e-3)" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "unprognostic (2.71e-2)" "unprognostic (3.43e-1)" "unprognostic (2.50e-1)" "unprognostic (4.56e-2)" 250.8 13.3 18.3 3.0 13.1 1.0 200.0 14.9 24.2 12.7 11.2 11.7 1.9 11.0 5.4 5.9 20.0 9.3 104.5 20.6 13.1 22.4 7.9 102.3 7.1 21.9 14.6 5.3 11.9 5.9 4.8 10.5 21.8 8.3 3.6 1.2 6.9 2.6 46.6 11.8 10.8 4.0 12.7 57.3 12.8 4.4 32.2 9.8 29.6 20.7 13.8 10.5 10.4 12.7 0.0 0.2 0.1 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 3.4 0.1 0.2 1.4 0.0 0.0 0.2 0.7 0.1 0.0 0.2 3.7 1.5 0.4 0.2 0.0 0.7 4.2 0.0 0.1 0.0 0.0 0.0 0.0 3.6 0.9 0.3 0.0 0.1 0.1 0.2 0.1 9.9 2.3 0.0 0.1 0.1 0.1 0.6 0.2 0.1 0.2 0.1 0.0 0.2 0.6 0.0 0.0 0.1 5.5 0.1 0.0 0.3 0.1 37.1 0.1 0.1 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 18.3 13.1 14.9 24.2 20.6 13.1 21.9 14.6 21.8 12.7 32.2 12.7 900.4 0.0 3.8 1.3 9.8 2.3 0.6 0.1 0.6 0.6 2.4 3.6 40.6 0.0 0.8 0.0 0.0 0.1 3.9 1.0 3.9 0.0 0.7 1.1 0.5 127.0 4.2 0.4 8.4 0.2 0.1 10.2 0.5 3.4 1.3 7.0 144.9 0.6 0.1 0.0 1.2 3.5 0.0 8.3 1.1 1.4 2.1 1.7 3.6 54.4 0.1 0.3 0.0 1.0 0.6 0.1 1.2 0.4 1.2 0.4 0.0 0.1 2.4 0.3 13.1 8.4 37.5 4.0 9.8 5.5 2.3 0.1 2.2 88.9 1.5 0.5 BZW1 "BZAP45, KIAA0005" ENSG00000082153 "Basic leucine zipper and W2 domains 1" Q7L1Q6 2 200810594-200827338 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 3845.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047288, HPA053272" Uncertain Approved Vesicles NA NA 34000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA047288: , HPA053272: " "unprognostic (2.45e-2)" "prognostic unfavorable (4.28e-4)" "unprognostic (2.08e-3)" "unprognostic (1.56e-2)" "unprognostic (1.93e-1)" "unprognostic (3.31e-3)" "unprognostic (3.98e-3)" "prognostic unfavorable (5.10e-4)" "unprognostic (4.49e-3)" "unprognostic (7.93e-3)" "unprognostic (1.08e-3)" "unprognostic (8.97e-3)" "unprognostic (4.38e-2)" "unprognostic (3.04e-1)" "unprognostic (7.61e-2)" "unprognostic (8.03e-2)" "unprognostic (1.24e-1)" 130.6 129.1 30.3 97.5 33.0 219.6 88.7 37.7 40.9 65.5 49.2 98.4 64.6 66.6 58.4 120.8 53.4 93.1 56.4 33.9 36.9 88.5 227.0 73.5 97.9 36.5 36.7 62.3 62.6 72.4 30.7 105.2 35.3 99.6 90.6 45.8 61.2 61.7 101.7 47.9 71.4 80.1 39.1 62.8 69.0 170.9 42.1 123.0 74.4 75.2 109.4 164.6 61.4 45.4 296.6 230.1 309.4 187.1 305.2 353.3 221.6 425.2 501.8 281.2 244.5 360.7 195.3 142.5 144.7 339.7 186.1 159.8 284.9 512.6 521.8 154.6 151.3 370.8 453.9 280.1 244.5 420.9 199.6 205.3 233.5 373.2 398.9 244.6 495.4 132.3 328.5 234.0 379.3 236.6 387.9 201.3 392.4 120.1 575.4 293.1 333.4 148.6 256.1 435.2 188.9 218.7 325.5 120.9 226.1 255.5 126.6 216.7 555.0 416.8 242.9 255.2 276.6 286.1 428.6 377.8 341.2 209.3 312.1 236.7 140.7 168.5 177.9 173.4 207.2 102.0 126.0 167.5 162.6 87.1 112.4 156.7 117.0 218.5 195.1 75.5 171.5 294.6 30.3 33.0 37.7 40.9 33.9 36.9 36.5 36.7 35.3 39.1 42.1 45.4 207.3 86.6 108.1 31.3 148.5 198.5 318.5 310.7 125.7 37.1 159.0 89.8 18.1 82.9 290.3 90.1 18.8 115.4 263.2 127.5 138.9 250.2 927.0 108.3 145.3 149.0 96.7 72.8 28.7 233.1 164.3 181.2 72.4 150.0 196.9 72.7 99.2 262.4 114.1 58.9 32.1 113.3 183.1 88.6 194.0 3845.6 102.2 169.1 124.5 15.0 308.1 119.6 170.0 24.6 36.6 464.4 106.5 95.9 132.7 242.3 68.2 163.3 121.7 33.4 98.6 159.4 179.8 175.2 169.2 133.2 196.1 195.2 200.3 103.3 106.1 370.9 C10orf62 bA548K23.1 ENSG00000203942 "Chromosome 10 open reading frame 62" Q5T681 10 97589721-97590934 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 155 "testis: 277.9" "Cell type enriched" "Detected in some" 5 "Late spermatids: 9848.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA072947 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "Nucleoplasm, Vesicles" "HPA072947: AB_2686562" "unprognostic (3.66e-2)" "unprognostic (3.97e-2)" "unprognostic (2.81e-1)" "unprognostic (5.36e-2)" "unprognostic (3.62e-1)" "unprognostic (1.20e-1)" "unprognostic (3.63e-2)" "unprognostic (2.53e-2)" "unprognostic (2.04e-2)" 0.0 0.2 0.3 0.0 0.8 0.0 0.2 1.4 0.4 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.5 0.7 0.7 0.0 0.0 0.9 1.0 0.0 0.3 0.1 0.2 0.0 0.9 0.3 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.5 0.0 0.0 277.9 0.8 0.0 0.1 0.3 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 1.4 0.4 0.3 0.5 0.9 1.0 0.9 0.5 0.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1711.8 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9848.3 39.4 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.2 0.0 0.0 0.0 0.3 0.0 0.0 6.6 0.0 0.0 40.7 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C10orf67 "bA215C7.4, C10orf115, LINC01552, MGC46732" ENSG00000179133 "Chromosome 10 open reading frame 67" Q8IYJ2 10 23202696-23344845 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 5.1;fallopian tube: 4.8;testis: 12.4" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 38.5;Early spermatids: 40.2;Endometrial ciliated cells: 18.2;Late spermatids: 32.8;Proximal tubular cells: 17.9;Respiratory ciliated cells: 35.7;Spermatocytes: 70.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HaCaT: 3.0;SiHa: 3.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA038131 Approved Approved Vesicles,Microtubules,Mitochondria NA No "Cluster 35: T-regs - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Vesicles, Microtubules, Mitochondria" "HPA038131: AB_10670658" "unprognostic (4.76e-4)" "unprognostic (2.38e-1)" "unprognostic (3.75e-2)" "unprognostic (2.92e-2)" "unprognostic (9.67e-3)" "unprognostic (1.91e-1)" "unprognostic (1.54e-1)" "unprognostic (1.78e-2)" "unprognostic (8.56e-2)" "unprognostic (1.78e-1)" "unprognostic (1.24e-2)" "unprognostic (2.46e-3)" "unprognostic (3.98e-1)" "unprognostic (3.59e-2)" "unprognostic (3.84e-3)" "unprognostic (9.58e-2)" 0.0 0.2 1.5 0.2 1.4 0.3 0.1 0.9 1.6 0.1 5.1 0.1 0.5 0.2 1.4 0.1 4.8 0.2 0.7 1.7 1.3 3.5 0.4 2.9 0.3 2.0 2.2 0.5 0.2 0.4 1.2 0.1 1.5 0.0 0.0 0.9 0.1 0.1 0.5 1.3 0.3 0.0 1.3 0.2 0.1 12.4 1.9 0.0 0.6 0.1 0.1 0.0 0.0 2.0 0.7 0.1 0.9 0.1 0.0 0.2 0.3 0.1 0.0 0.9 0.8 0.2 1.3 0.1 0.1 0.8 0.1 3.0 0.1 0.3 0.8 0.3 0.2 0.3 0.7 0.2 0.5 0.1 0.2 0.2 1.0 0.3 0.4 0.1 0.0 0.1 0.3 0.5 0.0 0.3 0.1 0.2 0.5 0.0 0.1 0.1 0.1 0.1 0.7 0.2 0.5 0.2 3.9 0.1 0.0 0.1 0.2 0.2 0.2 0.2 0.8 0.2 0.1 0.5 0.1 0.0 1.1 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.1 0.2 0.3 0.2 0.0 0.3 0.2 0.2 0.0 0.2 0.1 0.2 1.2 0.0 1.5 1.4 0.9 1.6 1.7 1.3 2.0 2.2 1.5 1.3 1.9 2.0 0.0 38.5 2.4 0.3 0.0 2.8 0.1 1.9 0.0 0.4 0.0 0.0 1.8 0.0 2.5 0.0 0.0 0.0 0.0 0.0 1.9 0.2 40.2 18.2 0.2 0.1 0.0 0.0 4.7 0.2 0.0 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 32.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 2.2 0.2 0.0 0.7 0.0 0.0 0.0 17.9 35.7 1.6 6.6 0.0 0.1 70.1 5.2 0.0 1.3 0.0 0.3 0.5 0.1 0.0 C11orf16 ENSG00000176029 "Chromosome 11 open reading frame 16" Q9NQ32 11 8920076-8933006 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 6.2;fallopian tube: 12.9;lymphoid tissue: 6.2" "Group enriched" "Detected in some" 8 "Endometrial ciliated cells: 40.8;Ionocytes: 28.5;Respiratory ciliated cells: 110.8" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA040644 Uncertain "Endoplasmic reticulum,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 49: Ciliated cells - Cilium organization" "Endoplasmic reticulum" Vesicles "HPA040644: " "unprognostic (5.32e-3)" "unprognostic (1.03e-2)" "unprognostic (4.09e-3)" "prognostic favorable (3.32e-4)" "unprognostic (1.73e-1)" "unprognostic (1.35e-2)" "unprognostic (1.94e-5)" "unprognostic (6.40e-4)" "unprognostic (1.58e-2)" "unprognostic (9.99e-2)" "unprognostic (4.87e-2)" "unprognostic (1.05e-1)" "unprognostic (1.84e-1)" "unprognostic (1.39e-1)" "unprognostic (1.23e-1)" "unprognostic (1.71e-1)" "unprognostic (1.13e-3)" 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.3 0.1 1.0 6.2 0.0 0.0 0.3 0.0 0.0 12.9 0.0 0.0 0.3 0.7 0.3 0.0 2.6 0.0 1.3 2.3 0.0 0.0 0.0 1.0 0.0 0.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 2.2 0.6 6.2 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.3 0.1 0.3 0.7 1.3 2.3 0.8 1.0 0.6 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.3 0.1 0.0 0.0 7.1 5.5 0.0 0.1 0.0 0.0 0.0 0.0 1.6 40.8 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 28.5 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 110.8 0.0 0.0 0.0 1.5 1.7 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 C11orf24 DM4E3 ENSG00000171067 "Chromosome 11 open reading frame 24" Q96F05 11 68261338-68272001 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 107.7;Proximal enterocytes: 162.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 222.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012411, HPA012748" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Golgi apparatus" Vesicles "HPA012411: , HPA012748: AB_1845526" "unprognostic (1.13e-2)" "unprognostic (2.03e-2)" "unprognostic (1.19e-1)" "unprognostic (8.22e-2)" "prognostic unfavorable (7.38e-4)" "unprognostic (2.31e-2)" "unprognostic (7.91e-2)" "prognostic unfavorable (6.05e-4)" "unprognostic (1.56e-1)" "unprognostic (2.68e-2)" "unprognostic (4.99e-2)" "unprognostic (1.55e-1)" "prognostic unfavorable (1.60e-9)" "unprognostic (2.18e-2)" "unprognostic (1.61e-1)" "unprognostic (2.21e-1)" "unprognostic (8.67e-3)" 25.0 17.6 8.9 20.7 12.2 4.7 21.0 12.1 12.7 23.3 8.2 29.2 53.8 39.2 7.3 15.5 22.2 17.6 31.5 9.7 10.5 17.0 87.4 24.1 15.5 14.4 11.6 19.3 27.3 7.3 14.5 16.1 12.5 22.9 17.4 3.0 34.0 17.6 13.7 15.4 59.4 32.6 11.0 20.8 23.6 14.6 12.8 6.4 17.0 15.2 16.7 22.3 19.4 15.2 44.8 45.5 26.4 51.6 62.1 62.5 29.7 105.4 67.5 51.8 53.1 96.2 26.9 20.1 31.7 131.3 47.2 49.4 39.1 47.4 33.2 22.1 23.1 21.4 44.8 65.3 50.1 18.3 68.7 52.1 34.6 78.8 32.0 31.0 21.2 10.6 37.9 32.2 44.6 55.7 4.5 26.4 44.2 72.1 53.8 8.2 44.8 104.1 23.9 21.1 17.3 31.8 33.3 27.1 222.8 21.8 25.6 15.3 23.3 80.8 50.2 103.3 47.3 39.4 41.4 18.8 65.1 14.1 79.9 16.7 12.1 12.6 14.0 19.0 9.4 26.7 7.9 8.9 19.5 35.7 7.3 7.7 1.8 9.9 14.1 26.7 8.4 12.6 8.9 12.2 12.1 12.7 9.7 10.5 14.4 11.6 12.5 11.0 12.8 15.2 6.8 9.6 3.6 3.3 25.5 14.0 12.2 11.7 9.6 4.8 8.2 8.9 10.4 11.5 6.9 9.2 2.1 11.9 12.4 36.2 1.9 21.9 3.5 5.3 17.8 6.6 4.8 9.1 4.1 31.5 30.7 21.1 18.3 6.8 45.0 5.0 9.3 107.7 15.8 0.0 4.2 50.0 6.1 12.9 23.5 7.1 14.0 12.3 28.4 5.6 14.9 6.8 18.6 6.6 8.5 26.9 16.6 16.1 67.0 13.0 162.5 10.6 9.4 2.9 13.1 11.2 20.2 20.7 27.1 9.6 11.2 10.5 6.5 9.6 15.5 10.6 C11orf42 MGC34805 ENSG00000180878 "Chromosome 11 open reading frame 42" Q8N5U0 11 6205557-6211135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "testis: 25.4" "Cell type enriched" "Detected in some" 5 "Late spermatids: 818.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.3;HeLa: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA063404 Enhanced Approved "Nuclear membrane,Vesicles,Plasma membrane" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "Nuclear membrane, Vesicles" "HPA063404: AB_2685006" "unprognostic (4.79e-2)" "unprognostic (1.83e-1)" "unprognostic (3.18e-1)" "unprognostic (2.56e-1)" "unprognostic (1.39e-3)" "unprognostic (3.49e-3)" "unprognostic (2.05e-1)" "unprognostic (5.39e-2)" "unprognostic (1.26e-1)" "unprognostic (3.50e-2)" "unprognostic (9.30e-2)" "unprognostic (6.47e-3)" "unprognostic (7.02e-2)" "unprognostic (1.09e-1)" "unprognostic (1.56e-1)" "unprognostic (2.07e-2)" "unprognostic (4.74e-2)" 0.0 0.1 0.5 0.2 0.5 0.1 0.1 1.4 0.7 0.1 0.0 0.3 0.9 0.3 0.0 0.1 0.1 0.1 0.1 0.4 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 1.4 0.2 0.0 0.1 1.5 0.7 0.0 0.0 0.2 0.3 25.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.1 0.8 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.2 0.2 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.2 1.3 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.3 0.1 0.0 0.2 0.3 0.1 0.4 0.1 0.4 0.2 0.3 0.0 0.0 0.1 0.4 0.1 0.0 0.3 0.1 0.1 0.1 0.3 0.1 0.3 0.1 0.6 0.1 0.1 0.3 0.1 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 1.4 0.7 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 146.5 0.0 0.0 0.1 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 818.5 1.5 0.2 0.0 1.0 0.0 0.0 0.0 2.0 2.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C11orf53 MGC50104 ENSG00000150750 "Chromosome 11 open reading frame 53" Q8IXP5 11 111245726-111286401 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "stomach 1: 3.4;testis: 5.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 14.3;Early spermatids: 38.1;Exocrine glandular cells: 56.6;Late spermatids: 12.4;Respiratory ciliated cells: 9.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "OE19: 3.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA056128, HPA073101" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm Vesicles "HPA056128: AB_2683046, HPA073101: " "unprognostic (3.51e-2)" "unprognostic (3.60e-2)" "unprognostic (4.84e-2)" "unprognostic (5.84e-2)" "unprognostic (1.94e-1)" "unprognostic (8.07e-3)" "unprognostic (5.60e-3)" "unprognostic (3.09e-1)" "unprognostic (2.50e-1)" "unprognostic (9.95e-2)" "unprognostic (8.66e-2)" "unprognostic (3.52e-2)" 0.9 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.1 0.0 1.4 0.9 0.9 0.0 0.0 0.9 1.4 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.5 0.6 1.3 0.4 0.7 0.0 0.3 1.0 0.0 2.1 0.0 1.8 0.0 1.2 0.0 0.0 0.0 3.4 5.5 0.0 0.4 0.0 1.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 4.6 0.0 0.0 0.0 0.1 0.1 14.3 3.3 0.0 0.0 0.0 0.1 1.5 0.0 1.9 38.1 0.0 1.4 0.0 7.7 0.0 0.1 56.6 0.1 1.9 3.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 3.0 8.2 0.0 0.0 12.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.4 0.2 0.3 4.0 0.0 9.9 0.0 0.0 0.1 0.6 1.0 1.1 0.0 0.0 0.0 0.0 0.0 1.7 4.4 C11orf91 ENSG00000205177 "Chromosome 11 open reading frame 91" Q3C1V1 11 33698261-33700801 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 9.5" "Cell type enhanced" "Detected in some" "Early spermatids: 16.6;Late spermatids: 4.0;Sertoli cells: 6.6;Spermatocytes: 12.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 16.2;hTERT-HME1: 10.0;HUVEC TERT2: 8.2;TIME: 12.6;U-2197: 10.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047064, HPA050487" Uncertain Supported Vesicles NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA047064: AB_2679920, HPA050487: AB_2681142" "unprognostic (9.22e-3)" "unprognostic (1.51e-2)" "unprognostic (1.76e-1)" "unprognostic (6.60e-2)" "unprognostic (1.62e-2)" "unprognostic (3.63e-2)" "unprognostic (2.31e-1)" "unprognostic (5.68e-3)" "unprognostic (7.41e-2)" "unprognostic (2.97e-2)" "unprognostic (1.99e-2)" "unprognostic (3.01e-1)" "unprognostic (8.33e-2)" "unprognostic (4.06e-2)" "unprognostic (3.95e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" 4.8 0.2 0.3 0.6 0.3 1.0 1.5 1.2 2.0 0.1 0.0 0.4 0.0 0.2 0.1 2.9 0.3 4.7 0.8 0.2 0.5 1.4 0.2 1.1 0.2 0.3 0.5 0.2 1.5 0.0 0.1 0.5 0.6 0.2 0.0 0.2 0.5 0.2 0.5 1.0 0.3 0.8 0.4 0.0 2.1 9.5 0.3 0.2 0.4 0.0 0.4 1.4 0.3 0.6 0.2 0.0 0.2 1.5 0.0 0.0 0.0 1.8 0.0 0.9 0.4 0.3 0.6 0.0 0.1 1.9 0.2 0.7 0.5 16.2 1.3 0.5 0.0 0.0 4.0 0.9 0.3 0.0 0.0 0.0 0.1 1.2 10.0 0.5 8.2 0.2 0.0 2.5 3.9 0.0 0.0 0.3 0.0 0.1 5.0 0.0 0.0 0.0 1.1 2.1 0.0 0.3 0.0 1.6 0.1 0.5 0.0 0.0 12.6 1.2 0.3 10.3 0.3 0.7 0.6 0.0 2.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.2 2.0 0.2 0.5 0.3 0.5 0.6 0.4 0.3 0.6 1.2 0.0 0.0 0.3 0.0 0.0 2.2 0.0 0.0 0.0 0.4 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 16.6 0.4 0.2 0.6 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.3 0.1 0.0 6.6 0.1 0.3 12.3 0.4 0.3 0.0 0.1 0.0 0.0 0.0 1.5 C12orf29 DKFZp434N2030 ENSG00000133641 "Chromosome 12 open reading frame 29" Q8N999 12 88033846-88050160 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039663 Uncertain Approved Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA039663: AB_10795253" "unprognostic (8.66e-2)" "unprognostic (1.39e-1)" "unprognostic (7.80e-2)" "unprognostic (6.88e-2)" "unprognostic (2.51e-2)" "unprognostic (2.06e-2)" "unprognostic (1.75e-3)" "unprognostic (4.72e-3)" "unprognostic (1.07e-2)" "unprognostic (1.84e-1)" "unprognostic (8.81e-2)" "unprognostic (6.49e-2)" "prognostic unfavorable (3.44e-4)" "unprognostic (1.03e-1)" "unprognostic (9.29e-2)" "unprognostic (2.03e-2)" "unprognostic (2.42e-1)" 4.7 9.8 7.5 4.5 8.1 8.7 11.0 7.0 10.0 6.5 4.9 4.8 4.8 6.6 12.8 16.1 4.5 5.2 5.8 8.1 7.8 8.4 12.6 5.1 6.8 7.5 7.8 7.5 5.9 7.2 3.1 5.3 7.6 8.2 5.1 5.4 8.3 6.1 4.3 15.5 3.9 5.6 7.8 5.3 5.2 5.6 7.1 6.2 9.9 8.7 8.7 7.4 6.0 8.8 13.1 8.1 7.9 9.2 16.7 21.5 5.8 17.1 14.6 14.4 12.9 7.8 5.0 24.0 2.3 8.8 8.1 11.3 15.5 11.8 24.8 10.4 15.9 20.5 6.5 6.9 20.1 26.9 9.4 14.7 17.8 13.5 16.8 16.8 11.2 9.2 20.3 4.8 22.7 4.6 18.0 13.6 12.0 11.0 15.7 10.4 13.5 19.9 16.3 10.4 19.0 17.0 9.8 22.8 12.5 6.5 14.6 19.2 9.0 12.9 4.3 13.3 13.4 10.7 16.0 14.5 10.0 19.1 11.4 4.5 0.8 0.6 2.7 0.8 4.9 2.0 3.9 3.3 1.0 1.7 4.6 3.9 0.0 3.4 0.9 1.4 2.1 1.8 7.5 8.1 7.0 10.0 8.1 7.8 7.5 7.8 7.6 7.8 7.1 8.8 20.4 9.6 13.6 7.8 17.7 51.5 29.2 29.1 21.6 14.4 19.0 17.8 16.1 20.0 29.6 5.5 6.2 15.3 16.1 5.1 37.2 21.5 34.2 14.2 16.8 17.7 7.8 44.6 22.8 24.2 17.1 26.4 8.2 19.1 10.8 6.7 9.7 16.4 9.6 10.1 20.0 8.9 18.3 6.6 11.7 22.8 32.0 6.6 26.6 4.7 5.3 16.2 11.3 5.0 12.9 22.3 5.0 30.9 13.5 39.7 4.2 33.3 19.7 17.8 6.6 24.9 25.2 50.4 31.7 29.5 71.5 9.3 21.3 8.6 13.0 31.2 C12orf75 "AGD3, OCC-1, OCC1" ENSG00000235162 "Chromosome 12 open reading frame 75" Q8TAD7 12 105235290-105396097 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 109.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 841.2;Ductal cells: 626.3;Endometrial ciliated cells: 579.1;Extravillous trophoblasts: 1228.2;Proximal tubular cells: 762.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 661.2" "Group enriched" "Detected in all" 6 "dendritic cells: 661.2;T-cells: 169.9" "Cell line enhanced" "Detected in all" "BJ: 877.8;BJ hTERT+: 517.0;fHDF/TERT166: 432.7;RPTEC TERT1: 425.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065311 Uncertain Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA065311: AB_2685463" "unprognostic (5.96e-2)" "unprognostic (3.85e-1)" "unprognostic (9.86e-2)" "unprognostic (1.02e-1)" "unprognostic (6.73e-2)" "unprognostic (8.58e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (8.61e-2)" "unprognostic (1.01e-1)" "unprognostic (2.60e-2)" "unprognostic (1.33e-1)" "unprognostic (7.00e-2)" "prognostic favorable (1.69e-5)" "unprognostic (1.80e-1)" "unprognostic (1.15e-1)" "unprognostic (1.00e-1)" "unprognostic (4.47e-3)" 12.2 7.3 4.3 8.9 4.7 11.3 11.6 9.4 7.2 31.3 2.1 24.9 9.2 18.5 6.1 8.7 20.9 38.2 2.5 4.1 8.8 58.5 2.0 7.5 14.7 5.3 5.5 6.6 33.8 20.1 3.5 9.3 4.9 41.2 22.0 2.8 4.2 109.3 32.0 9.5 8.8 6.7 6.5 6.3 49.9 26.6 8.8 10.8 2.9 11.8 19.1 5.0 27.0 5.4 43.6 66.6 16.5 14.9 61.2 117.3 30.3 877.8 517.0 194.2 109.4 133.2 3.6 12.2 348.9 432.7 31.7 70.4 36.6 50.3 212.9 241.1 65.0 38.8 17.7 26.5 7.7 29.8 37.7 49.6 12.0 66.4 73.8 113.0 26.1 69.9 1.9 58.8 192.4 14.4 115.3 262.5 39.6 15.8 153.3 21.6 44.3 11.2 425.3 4.3 73.5 18.4 36.9 7.7 16.2 45.2 22.6 7.1 44.2 201.7 77.2 77.0 118.1 34.9 57.6 58.8 44.5 9.7 55.3 39.0 0.7 1.2 165.5 0.5 80.4 19.7 69.2 169.9 23.3 16.2 19.8 102.4 3.5 69.4 1.6 661.2 144.1 88.3 4.3 4.7 9.4 7.2 4.1 8.8 5.3 5.5 4.9 6.5 8.8 5.4 12.8 3.2 2.8 1.6 61.2 100.2 65.9 21.9 38.7 4.5 32.2 26.9 1.1 271.7 20.9 187.6 4.2 35.3 519.5 469.8 841.2 626.3 152.3 579.1 32.6 14.8 333.2 15.8 2.7 222.3 1228.2 53.0 160.5 293.1 2.5 9.7 13.2 1.8 31.9 63.9 2.9 63.6 85.5 5.3 97.3 324.1 15.5 48.2 60.5 40.3 29.1 6.4 299.7 0.5 0.4 420.0 175.5 4.9 160.3 87.0 102.1 762.3 129.7 4.9 6.6 8.6 127.8 102.9 118.6 37.1 61.2 40.6 143.0 0.7 63.9 37.3 C15orf61 LOC145853 ENSG00000189227 "Chromosome 15 open reading frame 61" A6NNL5 15 67521131-67530146 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 23.7" "Cell type enhanced" "Detected in all" "Early spermatids: 222.6;Spermatocytes: 258.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062820 Approved Nucleoli,Vesicles,Cytosol "Secreted - unknown location" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Vesicles" Cytosol "HPA062820: AB_2684874" "unprognostic (1.35e-1)" "unprognostic (9.42e-3)" "unprognostic (2.11e-1)" "unprognostic (5.41e-2)" "unprognostic (2.40e-1)" "unprognostic (2.49e-1)" "unprognostic (1.49e-1)" "unprognostic (3.87e-3)" "unprognostic (8.95e-2)" "unprognostic (4.01e-2)" "unprognostic (1.04e-2)" "unprognostic (8.45e-2)" "prognostic favorable (5.31e-5)" "unprognostic (2.42e-2)" "unprognostic (9.78e-2)" "unprognostic (1.42e-1)" "unprognostic (8.32e-2)" 4.7 3.8 2.3 1.5 6.2 5.3 3.6 7.1 4.2 3.1 0.0 2.3 2.8 2.3 1.9 2.0 2.9 1.5 5.7 3.8 1.6 3.0 2.5 2.3 1.3 1.0 2.4 2.7 4.2 4.4 5.1 2.0 1.0 2.5 2.2 10.8 2.6 2.1 23.7 4.1 1.8 1.4 0.7 1.7 2.4 7.7 2.1 1.4 2.8 8.3 1.0 2.2 2.4 2.3 4.2 4.4 1.1 4.9 5.0 7.2 3.1 1.8 3.2 3.3 2.6 3.4 2.9 3.5 3.8 2.0 3.9 4.9 4.4 1.2 2.7 2.1 10.4 3.7 3.3 4.6 3.2 4.6 3.0 7.5 3.4 1.1 4.0 2.4 1.6 10.6 4.3 7.6 1.0 2.4 3.8 7.6 1.8 3.3 5.6 5.1 2.5 13.0 2.3 2.9 6.4 4.8 3.2 3.0 6.1 2.1 2.7 7.1 1.6 4.4 6.8 5.5 4.7 7.1 11.2 8.5 1.9 9.0 2.2 7.9 4.3 7.8 4.5 3.7 5.2 5.3 5.9 4.5 4.8 3.6 6.2 5.0 0.5 3.8 3.2 4.9 4.0 3.5 2.3 6.2 7.1 4.2 3.8 1.6 1.0 2.4 1.0 0.7 2.1 2.3 28.0 22.4 13.5 4.9 23.1 67.2 32.6 32.3 120.7 75.5 55.7 82.3 74.5 18.6 14.3 16.5 37.5 42.6 23.8 38.6 80.3 25.1 222.6 17.5 24.2 26.8 27.1 11.8 14.8 29.8 31.9 56.8 15.8 17.1 34.8 15.2 22.9 44.7 30.5 13.5 15.7 47.5 48.8 24.8 25.6 42.6 41.0 19.9 37.4 3.7 15.6 97.1 23.7 5.0 8.5 27.6 48.4 25.6 37.4 63.3 49.0 77.1 8.4 93.9 32.9 38.2 38.7 258.9 52.1 62.7 60.9 20.5 34.4 28.9 39.2 20.0 C16orf72 "FLJ41272, PRO0149" ENSG00000182831 "Chromosome 16 open reading frame 72" Q14CZ0 16 9091644-9121635 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 106.1" "Cell type enhanced" "Detected in all" "Late spermatids: 643.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041568, HPA067492" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 42: Non-specific - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm Vesicles "HPA041568: AB_10796677, HPA067492: AB_2685850" "unprognostic (3.98e-2)" "unprognostic (4.74e-2)" "unprognostic (5.87e-3)" "unprognostic (1.35e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (3.62e-4)" "unprognostic (1.37e-1)" "unprognostic (3.17e-2)" "unprognostic (1.76e-1)" "unprognostic (1.79e-1)" "unprognostic (6.74e-2)" "unprognostic (8.64e-2)" "unprognostic (7.92e-3)" "unprognostic (2.03e-1)" "unprognostic (1.29e-2)" "unprognostic (6.64e-3)" "unprognostic (6.51e-2)" 20.0 17.4 15.7 18.2 17.8 106.1 17.2 14.9 20.3 15.9 14.0 14.9 14.8 15.2 17.3 19.6 12.8 19.0 15.8 18.8 16.7 18.6 26.8 17.5 20.1 14.1 15.8 14.2 18.6 22.3 9.8 17.1 14.9 15.9 15.0 20.8 14.2 14.7 32.4 17.0 13.6 16.8 13.8 20.9 15.8 17.3 16.8 19.4 18.8 27.8 22.0 17.8 15.2 16.8 17.3 18.9 29.6 27.1 34.4 26.7 15.5 33.2 27.6 18.8 19.3 15.9 22.0 30.8 18.6 38.6 14.8 19.8 27.5 29.4 39.2 20.3 15.4 20.7 27.2 33.6 44.4 26.3 23.2 40.7 45.3 31.5 44.7 30.1 33.1 31.7 31.6 45.7 33.6 24.9 23.5 23.3 36.1 17.7 16.5 39.6 36.1 33.1 24.6 31.3 19.1 21.4 39.9 27.8 35.1 27.4 32.1 26.6 38.3 36.6 24.0 47.6 21.7 51.7 48.0 42.5 32.6 23.2 30.3 5.5 2.8 3.2 3.7 3.1 4.2 2.5 3.1 2.6 2.2 3.0 3.5 3.2 10.9 2.3 3.4 2.8 2.7 1.7 15.7 17.8 14.9 20.3 18.8 16.7 14.1 15.8 14.9 13.8 16.8 16.8 65.3 48.1 37.2 17.6 47.5 76.9 45.4 13.0 78.6 43.6 81.6 53.8 39.3 35.8 19.1 22.0 87.6 29.6 76.0 45.8 19.6 28.1 210.0 75.7 75.1 52.5 48.2 21.7 27.6 29.4 35.7 42.9 35.2 115.7 18.3 51.9 38.6 59.5 32.5 43.7 28.2 35.1 8.2 83.8 65.6 643.5 24.5 83.5 32.0 28.1 49.0 41.8 33.0 24.6 33.3 38.9 37.7 27.1 59.2 52.0 44.5 36.8 15.9 51.2 32.9 78.0 56.3 41.5 22.3 84.5 64.4 57.1 58.8 35.3 34.9 70.1 C17orf64 ENSG00000141371 "Chromosome 17 open reading frame 64" Q86WR6 17 60392429-60431426 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 173 "testis: 135.3" "Group enriched" "Detected in some" 25 "Early spermatids: 1057.0;Late spermatids: 524.2;Spermatocytes: 287.9" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.5" "Group enriched" "Detected in many" 4 "dendritic cells: 2.5;granulocytes: 1.0" "Cell line enriched" "Detected in some" 4 "MCF7: 5.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA044415 Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 74: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Vesicles "HPA044415: AB_10797148" "unprognostic (3.00e-1)" "unprognostic (2.60e-2)" "unprognostic (2.36e-1)" "unprognostic (6.50e-2)" "unprognostic (1.77e-1)" "unprognostic (1.51e-2)" "unprognostic (2.30e-2)" "unprognostic (3.24e-1)" "unprognostic (1.43e-1)" "unprognostic (1.80e-1)" "unprognostic (6.85e-2)" "unprognostic (1.68e-6)" "unprognostic (3.30e-1)" "unprognostic (2.77e-1)" "unprognostic (2.80e-2)" "unprognostic (5.46e-2)" 0.3 0.1 0.3 0.0 0.1 0.6 0.2 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.4 0.3 0.0 0.1 0.1 0.6 0.4 0.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.5 0.1 135.3 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.3 0.4 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.3 0.8 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.3 0.0 5.8 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.8 0.7 0.1 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.4 0.1 0.0 0.8 0.0 0.0 0.2 1.0 0.0 0.0 2.5 0.0 0.0 0.3 0.1 0.2 0.7 0.2 0.4 0.6 0.4 0.4 0.2 0.4 0.6 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1057.0 0.0 0.1 0.4 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.4 524.2 9.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 287.9 24.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 C17orf80 "FLJ20721, HLC-8, MIG3, SPEP1" ENSG00000141219 "Chromosome 17 open reading frame 80" Q9BSJ5 17 73232233-73248947 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 170.0;Late spermatids: 100.8;Spermatocytes: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012896 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Vesicles" "HPA012896: AB_1850766" "unprognostic (9.22e-2)" "unprognostic (1.62e-1)" "prognostic favorable (1.43e-4)" "unprognostic (5.55e-3)" "unprognostic (8.58e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (9.02e-6)" "unprognostic (1.08e-1)" "unprognostic (1.00e-3)" "unprognostic (1.84e-2)" "unprognostic (1.20e-3)" "unprognostic (6.09e-2)" "unprognostic (1.21e-2)" "unprognostic (1.45e-1)" "unprognostic (1.52e-1)" "unprognostic (2.36e-3)" "unprognostic (1.37e-1)" 8.6 10.1 10.0 9.5 10.1 3.1 11.2 12.7 12.1 11.9 9.2 11.6 10.5 14.5 9.7 8.8 12.2 8.9 15.8 9.7 10.2 12.7 9.9 9.2 13.7 8.3 9.2 17.2 9.3 16.6 10.6 12.5 8.4 12.6 10.0 23.3 10.8 11.9 24.6 8.7 9.8 12.8 9.0 10.8 10.3 39.7 9.6 17.9 16.1 21.8 12.2 9.1 6.9 9.9 20.0 20.6 28.1 17.2 20.2 17.2 27.2 25.6 22.2 35.6 33.6 19.7 16.1 37.7 17.8 13.2 24.2 19.5 39.4 14.7 41.4 13.8 26.8 34.6 21.5 23.3 17.6 37.0 19.7 13.5 18.1 23.8 19.5 17.8 30.9 25.1 38.3 21.9 24.0 11.5 43.1 17.5 22.3 22.1 22.1 25.7 77.2 19.3 18.4 14.9 34.3 30.8 13.7 24.7 30.0 44.0 27.1 23.0 17.1 37.1 34.0 12.1 24.8 24.7 31.9 35.8 14.9 16.5 24.1 17.3 3.3 4.8 6.6 4.0 6.6 4.9 4.9 5.9 3.8 4.7 4.5 6.6 1.6 4.4 4.4 5.8 7.2 3.4 10.0 10.1 12.7 12.1 9.7 10.2 8.3 9.2 8.4 9.0 9.6 9.9 10.3 6.4 15.1 10.7 6.4 5.0 2.1 3.0 8.6 10.3 6.1 7.2 20.2 5.7 7.9 5.5 20.9 9.5 14.9 4.6 9.8 6.1 170.0 8.9 12.3 11.0 5.4 1.3 10.8 3.8 5.8 9.6 5.6 7.0 7.6 11.8 5.0 4.6 5.0 8.4 10.9 3.8 6.1 5.1 2.6 100.8 5.3 4.8 1.8 9.4 5.9 10.6 4.1 10.1 9.0 4.5 5.1 7.5 5.9 2.1 6.6 7.5 15.8 15.8 0.0 10.5 7.7 67.1 13.6 7.1 4.4 16.8 5.5 17.9 4.8 1.4 C18orf32 FLJ23458 ENSG00000177576 "Chromosome 18 open reading frame 32" Q8TCD1 18 49477243-49487252 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 238.5;Late spermatids: 233.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040921 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 34: Spermatids - Unknown function" Vesicles Nucleoplasm "HPA040921: AB_10795423" "unprognostic (5.83e-2)" "unprognostic (5.48e-2)" "unprognostic (5.54e-2)" "unprognostic (3.13e-2)" "unprognostic (4.19e-2)" "unprognostic (1.44e-1)" "unprognostic (1.72e-1)" "unprognostic (2.80e-2)" "unprognostic (6.36e-2)" "unprognostic (4.36e-3)" "unprognostic (2.58e-3)" "unprognostic (2.76e-2)" "prognostic favorable (8.89e-9)" "unprognostic (1.02e-1)" "unprognostic (7.42e-2)" "unprognostic (1.28e-2)" "unprognostic (4.36e-2)" 41.5 66.7 10.8 5.6 13.8 6.8 39.8 15.3 20.0 34.9 8.3 46.0 6.1 35.6 5.6 32.3 34.5 6.6 59.3 11.3 13.5 79.6 86.8 46.5 7.9 14.8 13.0 38.8 47.0 18.5 67.9 6.9 14.0 39.4 10.2 24.6 43.7 8.4 37.9 27.8 39.9 7.3 13.4 39.2 58.1 40.9 13.1 8.5 43.9 7.2 10.4 38.8 32.6 18.7 4.3 3.2 14.4 13.3 12.3 8.8 8.6 5.5 7.6 6.0 6.8 0.5 3.7 4.9 8.6 7.9 9.0 11.1 5.1 10.6 12.6 11.3 4.1 4.2 2.3 5.4 11.2 5.1 11.2 9.9 21.0 5.0 6.1 16.0 12.2 10.1 4.1 11.4 9.9 1.9 4.6 2.5 4.7 4.9 5.9 4.0 3.6 3.8 7.1 5.0 10.7 12.3 5.1 3.4 4.4 19.8 3.1 2.3 13.1 9.6 5.0 1.7 6.9 13.4 24.1 9.1 5.2 5.9 7.1 27.4 8.4 25.8 8.4 8.8 8.7 8.9 6.9 7.7 6.6 7.4 6.6 8.4 41.4 6.2 11.3 9.5 8.2 10.3 10.8 13.8 15.3 20.0 11.3 13.5 14.8 13.0 14.0 13.4 13.1 18.7 20.2 44.8 29.2 0.0 50.8 5.5 4.6 21.2 39.3 35.0 26.2 15.0 5.5 31.5 22.4 23.9 43.8 22.9 33.8 92.9 39.2 87.5 238.5 38.1 21.0 17.5 95.5 20.2 0.0 82.7 17.7 28.7 63.2 30.3 45.6 5.3 23.6 40.4 22.1 18.5 0.0 57.3 32.6 38.0 12.0 233.1 17.1 48.1 23.2 0.0 73.9 41.4 34.0 0.0 0.0 92.3 77.5 10.1 83.0 5.6 92.7 57.2 42.4 36.3 19.7 10.3 22.7 12.7 13.9 58.4 7.7 38.7 43.4 4.5 40.8 5.2 C19orf81 ENSG00000235034 "Chromosome 19 open reading frame 81" C9J6K1 19 50649445-50659310 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 12 "brain: 2.4;testis: 6.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 20.2;Early spermatids: 30.7;Muller glia cells: 65.4;Rod photoreceptor cells: 29.3;Spermatocytes: 17.1" "Cancer enhanced" "Detected in many" "ovarian cancer: 5.1" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 4.3;HMC-1: 1.5;JURKAT: 1.2;K-562: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA060238 Enhanced Approved Vesicles,Aggresome NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" "Vesicles, Aggresome" "HPA060238: AB_2684228" "unprognostic (2.29e-2)" "unprognostic (2.75e-2)" "unprognostic (2.17e-3)" "unprognostic (1.15e-1)" "unprognostic (3.39e-2)" "unprognostic (2.03e-2)" "unprognostic (1.70e-2)" "unprognostic (4.21e-2)" "unprognostic (2.83e-1)" "unprognostic (1.48e-2)" "unprognostic (6.01e-4)" "unprognostic (4.41e-1)" "unprognostic (1.17e-2)" "unprognostic (3.77e-1)" "unprognostic (7.58e-2)" "unprognostic (1.95e-1)" "unprognostic (5.04e-2)" 0.0 0.0 0.6 0.0 0.5 0.1 0.0 2.4 1.3 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.8 0.6 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.3 0.1 0.0 0.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 6.9 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.5 4.3 0.4 0.0 0.0 0.2 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.2 1.2 1.0 0.8 0.0 0.0 0.2 0.7 0.2 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.5 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.5 2.4 1.3 0.8 0.6 0.7 0.4 0.8 0.2 0.4 0.8 0.2 0.0 0.0 0.3 0.5 2.2 1.7 0.0 12.0 14.9 4.0 4.3 1.3 1.5 0.0 20.2 8.4 0.1 3.0 0.1 13.7 7.9 30.7 2.3 1.4 1.5 0.0 0.8 1.5 1.3 0.3 0.9 0.0 5.4 0.0 1.4 1.8 0.0 0.9 11.8 2.1 0.0 0.0 0.3 0.8 6.4 0.6 0.9 5.4 1.0 2.6 65.4 0.0 1.5 3.5 4.4 0.0 0.7 0.1 6.0 0.0 0.2 0.0 29.3 0.0 1.1 1.8 17.1 5.0 0.9 4.3 0.0 0.8 2.7 0.0 0.4 C19orf84 ENSG00000262874 "Chromosome 19 open reading frame 84" I3L1E1 19 51388289-51390591 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 30 "testis: 22.1" "Cell type enriched" "Detected in some" 10 "Spermatogonia: 31.9" "Group enriched" "Detected in some" 5 "ovarian cancer: 1.3;testis cancer: 3.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "K-562: 6.9" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA068082 Uncertain Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 78: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Vesicles "HPA068082: AB_2685949" "unprognostic (5.94e-2)" "unprognostic (7.72e-2)" "unprognostic (8.51e-2)" "unprognostic (1.43e-3)" "unprognostic (2.08e-1)" "unprognostic (1.47e-1)" "unprognostic (2.13e-3)" "unprognostic (9.28e-4)" "unprognostic (1.31e-1)" "unprognostic (1.87e-1)" "unprognostic (1.29e-1)" "unprognostic (3.84e-1)" "unprognostic (2.61e-7)" "unprognostic (8.30e-3)" "unprognostic (1.86e-1)" "unprognostic (2.92e-2)" "unprognostic (3.99e-3)" 0.0 0.0 0.4 0.2 0.4 0.6 0.0 0.4 0.7 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.4 0.0 0.0 0.1 0.3 0.4 0.5 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.4 0.0 22.1 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.4 0.4 0.7 0.4 0.4 0.4 0.5 0.5 0.3 0.5 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 0.0 2.2 0.3 0.3 0.0 0.0 0.2 0.0 3.1 0.0 0.0 0.0 1.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 31.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 C1GALT1C1 "C1GALT2, COSMC" ENSG00000171155 "C1GALT1 specific chaperone 1" Q96EU7 X 120625674-120630054 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" Chaperone "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 107.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 126.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010666, HPA015632" Approved Approved Vesicles NA NA 21000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 51: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA010666: , HPA015632: AB_1845625" "prognostic unfavorable (5.66e-4)" "unprognostic (1.21e-1)" "unprognostic (1.21e-1)" "unprognostic (1.98e-1)" "unprognostic (3.07e-2)" "unprognostic (5.26e-3)" "unprognostic (4.34e-2)" "unprognostic (2.50e-1)" "unprognostic (2.18e-2)" "unprognostic (8.10e-2)" "unprognostic (3.85e-2)" "unprognostic (3.07e-1)" "unprognostic (3.98e-2)" "unprognostic (4.48e-2)" "unprognostic (1.55e-1)" "unprognostic (6.05e-3)" "unprognostic (3.78e-2)" 15.3 27.8 4.2 8.7 4.6 2.8 14.5 4.9 5.6 15.7 6.4 15.7 10.1 12.2 16.8 14.8 13.7 8.3 17.7 4.2 5.9 13.8 21.0 12.0 8.8 4.9 5.2 9.7 15.8 16.3 33.9 9.2 4.9 10.5 14.5 6.3 20.0 11.1 7.8 5.8 13.2 9.5 4.8 13.0 13.5 6.1 4.5 7.4 13.2 7.0 9.6 11.5 12.8 5.2 15.9 15.1 8.2 14.2 126.7 24.0 13.0 28.4 39.9 14.7 27.7 9.9 49.8 10.3 13.9 57.6 28.4 21.9 16.2 13.9 23.4 17.6 19.6 6.6 13.1 14.7 19.7 11.7 10.1 21.0 12.1 18.3 6.1 36.9 47.0 5.1 4.2 11.8 17.5 21.6 3.9 11.0 9.3 53.3 15.1 1.8 6.4 28.5 29.9 10.6 9.0 8.6 27.0 18.4 14.6 15.0 15.9 11.2 43.4 6.7 8.3 27.2 26.9 5.1 7.9 8.2 24.6 22.7 15.0 12.1 12.3 20.4 12.0 16.4 13.3 12.3 15.4 13.0 14.6 7.6 15.6 12.5 22.7 12.3 13.6 16.7 15.8 12.2 4.2 4.6 4.9 5.6 4.2 5.9 4.9 5.2 4.9 4.8 4.5 5.2 27.1 6.4 10.4 6.5 16.3 6.8 22.7 107.9 15.4 8.3 17.6 10.0 17.6 14.3 75.9 38.6 2.1 56.9 16.3 18.7 15.6 40.3 2.7 30.5 20.2 27.6 13.8 5.9 4.7 44.3 51.7 34.7 10.7 25.3 2.5 14.5 21.4 22.3 24.1 20.2 6.5 20.8 77.3 16.2 11.4 6.4 22.7 19.6 30.2 3.7 20.7 17.5 15.5 5.5 10.1 30.0 20.8 19.2 50.1 10.7 16.9 20.3 71.0 10.5 6.6 18.1 24.4 6.5 8.4 14.1 7.2 20.0 15.2 25.8 21.5 20.5 C1orf53 ENSG00000203724 "Chromosome 1 open reading frame 53" Q5VUE5 1 197902630-197907367 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 15.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 64.6;Theca cells: 55.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 8.9" "Lineage enriched" "Detected in many" 4 "monocytes: 8.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065352 Approved Vesicles,Aggresome NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles Aggresome "HPA065352: AB_2685477" "prognostic favorable (1.63e-4)" "unprognostic (1.48e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (3.78e-4)" "unprognostic (1.72e-1)" "unprognostic (1.37e-1)" "unprognostic (2.22e-2)" "unprognostic (5.24e-2)" "unprognostic (8.90e-3)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (1.54e-1)" "unprognostic (5.53e-3)" "unprognostic (9.85e-2)" "unprognostic (1.12e-1)" "unprognostic (8.58e-3)" "unprognostic (1.37e-1)" 1.7 9.4 2.6 0.5 2.1 0.8 1.4 1.9 3.6 1.5 5.1 2.8 1.8 1.0 3.1 3.0 0.9 0.8 6.7 2.7 2.2 5.1 15.1 1.9 0.5 2.3 2.6 2.3 2.7 0.4 5.0 0.8 2.1 1.4 1.3 0.5 2.3 0.4 3.7 0.9 1.9 0.8 1.8 1.6 1.8 3.1 3.3 0.3 2.7 1.4 0.3 1.2 1.5 2.5 4.4 6.0 0.4 2.1 3.7 10.5 3.3 7.5 5.4 6.2 3.1 5.4 3.7 8.5 11.8 8.5 1.4 2.0 2.2 1.4 0.6 2.7 15.8 5.0 3.7 8.6 1.0 11.2 6.8 7.1 4.8 1.9 0.8 5.0 2.2 1.8 1.4 2.1 4.7 7.9 0.6 10.1 4.7 6.9 8.7 1.1 3.4 3.1 10.1 6.9 18.4 14.4 9.5 1.6 3.2 2.3 4.5 4.3 5.1 7.2 8.0 10.2 5.2 3.6 2.6 2.2 5.2 3.6 9.0 0.0 2.7 0.0 0.3 8.9 0.0 0.0 0.1 0.6 2.1 0.1 0.3 0.3 0.0 0.0 4.4 0.6 0.1 0.9 2.6 2.1 1.9 3.6 2.7 2.2 2.3 2.6 2.1 1.8 3.3 2.5 0.5 9.6 10.6 0.3 1.6 2.5 4.1 13.1 4.0 2.2 16.3 20.8 11.7 18.6 15.1 22.0 0.0 18.9 0.3 14.8 19.6 9.9 15.7 16.2 6.7 2.0 7.8 4.8 2.0 13.8 10.2 5.5 4.1 12.1 1.3 8.6 2.2 64.6 9.5 3.3 1.5 12.6 14.2 4.1 1.8 2.7 14.0 4.7 8.8 0.0 2.6 11.5 4.1 1.0 0.8 9.3 8.8 10.5 6.0 6.7 10.8 25.8 12.2 3.9 0.0 1.4 6.1 8.6 4.5 12.4 2.8 11.8 1.1 55.8 16.6 5.7 C1QTNF12 "ADIPOLIN, C1QDC2, CTRP12, FAM132A, MGC105127" ENSG00000184163 "C1q and TNF related 12" Q5T7M4 1 1242446-1246722 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 6.8;skin 1: 6.6" "Cell type enhanced" "Detected in some" "Adipocytes: 19.5;Extravillous trophoblasts: 11.2;Proximal tubular cells: 45.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "EFO-21: 4.1;U-2 OS: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA024107 Uncertain Approved Vesicles "Secreted to blood" NA NA 38200000 "Cluster 40: NK-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA024107: AB_2101207" "unprognostic (1.10e-2)" "unprognostic (5.68e-3)" "unprognostic (3.45e-1)" "unprognostic (1.24e-2)" "unprognostic (6.60e-3)" "unprognostic (2.43e-1)" "unprognostic (2.67e-3)" "unprognostic (1.01e-2)" "unprognostic (2.58e-1)" "unprognostic (1.05e-2)" "unprognostic (8.02e-3)" "unprognostic (1.10e-2)" "unprognostic (9.68e-3)" "unprognostic (1.48e-1)" "unprognostic (2.47e-1)" "unprognostic (1.09e-1)" "unprognostic (1.20e-1)" 1.3 0.1 0.4 0.2 0.4 0.0 0.7 0.3 0.5 0.5 0.0 3.4 6.8 0.3 0.0 1.3 0.5 0.1 0.8 0.4 0.7 3.4 0.5 0.4 0.0 0.8 0.4 0.2 0.2 0.0 0.3 0.2 0.5 0.3 0.7 0.0 0.3 0.0 0.4 6.6 6.7 0.0 0.4 0.2 0.4 2.4 0.9 0.0 0.4 0.0 0.1 0.3 0.6 0.5 0.1 0.0 0.0 0.3 0.2 0.0 0.8 0.6 0.0 0.0 0.0 0.3 0.2 0.0 4.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.1 0.1 0.4 0.3 0.1 0.1 0.0 0.7 0.0 0.0 0.6 0.1 0.0 0.0 0.4 0.0 0.3 0.1 0.0 0.0 4.0 0.0 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.5 0.4 0.7 0.8 0.4 0.5 0.4 0.9 0.5 19.5 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.6 2.9 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 3.9 0.5 0.0 0.6 1.2 0.7 0.0 0.0 0.0 0.8 11.2 0.5 0.0 0.7 2.5 0.8 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 45.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.4 0.3 0.0 0.0 C1QTNF4 "CTRP4, ZACRP4" ENSG00000172247 "C1q and TNF related 4" Q9BXJ3 11 47589667-47594411 "Predicted secreted proteins" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.0;pituitary gland: 17.1" "Cell type enhanced" "Detected in many" "Late spermatids: 51.7;Leydig cells: 46.0;Muller glia cells: 54.5;Peritubular cells: 38.4;Spermatogonia: 44.5;Theca cells: 39.0" "Group enriched" "Detected in some" 4 "glioma: 1.7;ovarian cancer: 2.5;testis cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "REH: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041032 Approved Uncertain "Golgi apparatus,Vesicles" "Secreted in brain" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 14: REH - Unknown function" "Cluster 52: Non-specific - Transcription" "Golgi apparatus, Vesicles" "HPA041032: AB_10671170" "unprognostic (1.84e-3)" "unprognostic (1.58e-1)" "unprognostic (8.98e-4)" "unprognostic (8.19e-2)" "unprognostic (3.59e-2)" "unprognostic (2.26e-3)" "unprognostic (6.78e-2)" "unprognostic (6.11e-2)" "unprognostic (6.35e-2)" "unprognostic (4.00e-1)" "unprognostic (4.91e-4)" "unprognostic (1.22e-1)" "unprognostic (8.22e-6)" "unprognostic (6.02e-3)" "unprognostic (1.00e-1)" "unprognostic (2.80e-2)" "unprognostic (6.28e-2)" 1.7 1.5 7.9 0.0 33.0 1.1 2.2 13.2 17.6 5.3 0.0 3.9 0.1 5.8 0.0 0.5 4.2 0.0 1.0 7.5 1.1 1.4 0.9 0.7 0.0 6.0 4.9 12.0 0.4 0.7 17.1 0.0 2.1 2.8 0.0 0.1 1.1 0.1 0.9 1.8 1.5 0.1 1.0 1.0 1.5 5.8 6.7 0.0 1.5 0.0 0.0 1.3 2.0 3.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.4 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 33.0 13.2 17.6 7.5 1.1 6.0 4.9 2.1 1.0 6.7 3.4 2.4 0.0 0.0 18.9 0.0 2.4 6.5 0.2 0.0 15.8 1.3 25.8 0.7 1.5 0.3 3.7 16.7 1.3 0.1 0.2 3.9 0.1 11.3 0.8 21.2 4.5 0.0 2.5 15.5 0.2 2.7 20.7 0.5 0.6 0.0 31.3 2.5 0.2 3.3 5.0 17.8 0.1 0.0 0.3 3.0 51.7 46.0 0.7 10.6 4.7 0.0 54.5 0.0 5.0 8.0 0.1 0.1 38.4 0.0 4.3 0.1 0.6 0.6 24.7 26.3 12.8 8.5 13.5 44.5 0.3 1.8 3.6 0.6 39.0 0.2 2.4 C1QTNF7 CTRP7 ENSG00000163145 "C1q and TNF related 7" Q9BXJ2 4 15339818-15446167 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 15.8;Fibroblasts: 32.3;Leydig cells: 22.7;Peritubular cells: 31.6;Skeletal myocytes: 15.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "ASC diff: 4.2;ASC TERT1: 2.8;HSkMC: 1.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB007055, HPA051797, HPA055392" Uncertain Approved Vesicles "Secreted to blood" NA NA 238000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB007055: , HPA051797: AB_2681614, HPA055392: AB_2732596" "unprognostic (6.61e-2)" "unprognostic (4.50e-2)" "unprognostic (6.16e-2)" "unprognostic (6.50e-4)" "unprognostic (1.24e-1)" "unprognostic (4.98e-3)" "unprognostic (2.31e-2)" "unprognostic (7.69e-3)" "unprognostic (7.61e-2)" "unprognostic (1.13e-1)" "unprognostic (2.41e-1)" "unprognostic (1.38e-1)" "unprognostic (2.97e-4)" "unprognostic (3.01e-3)" "unprognostic (8.31e-2)" "unprognostic (7.56e-3)" "unprognostic (7.28e-3)" 7.8 1.4 1.2 1.6 1.2 0.0 4.7 1.2 2.6 23.1 0.0 8.6 1.2 16.5 10.2 6.0 6.3 14.0 7.0 0.8 1.8 5.5 1.2 10.8 1.2 1.1 1.8 20.9 0.8 0.1 1.1 7.2 0.9 9.5 4.2 0.1 2.5 3.2 0.6 3.2 3.8 12.0 0.6 9.7 9.0 1.7 1.8 0.4 3.8 6.6 0.5 10.3 10.3 1.3 0.0 0.0 0.0 0.0 4.2 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.2 2.6 0.8 1.8 1.1 1.8 0.9 0.6 1.8 1.3 1.2 0.0 0.0 1.0 0.0 3.6 0.0 0.0 0.0 15.8 0.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.1 0.2 6.5 0.5 0.0 0.0 1.0 0.0 0.3 32.3 0.0 0.6 0.0 2.0 0.0 0.0 0.1 1.7 4.4 0.0 0.0 0.0 3.2 0.5 22.7 0.3 5.4 6.5 0.0 0.3 0.0 2.5 0.7 0.0 0.0 31.6 0.2 0.1 0.0 2.8 0.0 1.2 6.6 15.2 9.9 0.0 0.1 0.6 3.0 0.0 0.7 5.7 0.0 0.1 C20orf173 dJ477O4.4 ENSG00000125975 "Chromosome 20 open reading frame 173" Q96LM9 20 35523186-35529652 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 45 "testis: 35.5" "Group enriched" "Detected in some" 76 "Early spermatids: 473.3;Late spermatids: 156.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA076859 Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Vesicles, Plasma membrane" "HPA076859: " "unprognostic (1.90e-1)" "unprognostic (1.03e-1)" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 473.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 156.5 4.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C2CD4C "FAM148C, KIAA1957, NLF3" ENSG00000183186 "C2 calcium dependent domain containing 4C" Q8TF44 19 405445-409147 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.4" "Cell type enhanced" "Detected in some" "Adipocytes: 13.2;Excitatory neurons: 3.6;Granulosa cells: 3.7;Hepatic stellate cells: 3.6;Rod photoreceptor cells: 7.6" "Cancer enhanced" "Detected in many" "testis cancer: 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 6.4;MCF7: 4.4;NTERA-2: 6.2;SCLC-21H: 11.1;U-2 OS: 6.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA055915 Uncertain Approved Vesicles NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA055915: AB_2682968" "unprognostic (1.29e-1)" "unprognostic (9.43e-2)" "unprognostic (5.79e-2)" "unprognostic (1.64e-1)" "unprognostic (9.39e-3)" "unprognostic (2.14e-1)" "unprognostic (1.67e-1)" "unprognostic (9.81e-2)" "unprognostic (1.81e-1)" "unprognostic (1.36e-1)" "unprognostic (1.19e-1)" "unprognostic (1.35e-1)" "unprognostic (1.12e-2)" "unprognostic (1.43e-2)" "unprognostic (5.04e-2)" "unprognostic (5.09e-2)" "unprognostic (1.74e-1)" 3.8 1.0 9.8 0.3 11.4 0.0 3.0 3.7 17.4 3.0 2.5 1.3 0.4 2.3 0.0 0.7 2.0 2.8 4.8 10.8 17.1 2.5 0.7 1.8 0.1 7.5 7.6 0.3 1.0 0.1 2.6 0.4 8.8 1.0 0.0 0.8 0.3 0.0 0.9 0.8 1.4 0.1 8.7 1.0 0.8 2.0 13.0 0.1 3.9 0.5 0.0 0.6 1.0 7.1 0.0 0.5 1.5 1.3 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.1 2.0 0.0 0.5 0.0 0.7 2.4 2.4 0.2 0.1 6.4 1.3 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.4 0.2 0.0 0.0 4.4 0.0 0.0 6.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 11.1 3.2 1.0 0.0 0.0 0.5 0.2 0.0 0.0 0.1 6.5 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 11.4 3.7 17.4 10.8 17.1 7.5 7.6 8.8 8.7 13.0 7.1 13.2 0.0 0.0 0.3 0.1 0.3 0.3 0.3 0.0 0.5 0.3 0.1 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.2 1.9 3.0 0.0 3.6 0.4 0.0 0.1 0.0 0.2 0.0 3.7 3.6 0.1 0.0 0.0 3.1 0.0 2.0 0.0 0.4 0.3 0.0 0.0 0.0 1.9 0.0 2.0 0.0 3.0 0.6 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.0 7.6 0.0 0.4 0.4 0.7 2.2 0.0 0.3 0.0 0.1 0.0 0.0 0.1 C3orf49 ENSG00000163632 "Chromosome 3 open reading frame 49" Q96BT1 3 63819299-63848636 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.7" "Group enriched" "Detected in some" 6 "Early spermatids: 19.5;Late spermatids: 34.4" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebral cortex: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 2.0;MCF7: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA053582 Uncertain Approved Vesicles,Centrosome,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "Vesicles, Centrosome" "HPA053582: AB_2682199" "unprognostic (2.90e-1)" "unprognostic (2.63e-1)" "unprognostic (4.81e-2)" "unprognostic (1.64e-1)" "unprognostic (1.07e-1)" "unprognostic (5.27e-3)" "unprognostic (1.79e-1)" "unprognostic (2.14e-2)" "unprognostic (9.29e-3)" "unprognostic (1.72e-1)" "unprognostic (5.14e-2)" "unprognostic (9.47e-3)" "unprognostic (7.61e-3)" "unprognostic (1.02e-1)" "unprognostic (7.68e-2)" "unprognostic (5.79e-2)" "unprognostic (1.07e-1)" 0.0 0.2 0.1 0.2 0.4 0.6 0.0 1.2 1.7 0.1 0.0 0.1 0.6 0.3 0.0 0.7 0.1 0.2 0.3 0.2 0.0 0.1 0.3 0.3 0.3 0.0 0.0 0.5 0.6 0.0 0.0 0.1 0.0 0.1 0.0 1.4 0.3 0.0 1.1 0.9 0.3 0.0 0.0 0.2 0.2 1.3 0.0 0.0 0.4 0.0 0.0 0.1 0.0 1.1 0.2 0.7 0.4 0.4 0.0 0.1 0.4 0.6 0.0 0.0 0.0 0.7 0.3 1.0 0.1 0.0 0.2 0.4 0.0 0.0 0.1 0.5 0.6 0.8 2.0 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.5 0.4 0.0 1.8 0.4 0.4 0.5 0.4 0.1 0.6 0.4 0.9 0.0 0.4 0.4 0.3 0.1 0.9 0.1 0.1 0.2 0.3 0.5 0.3 0.4 0.6 0.7 0.2 0.9 0.1 0.9 1.4 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.4 1.2 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.0 0.2 0.1 0.5 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 19.5 0.2 0.2 0.1 0.0 0.0 3.9 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.0 34.4 0.3 0.0 0.0 1.0 0.1 0.2 0.0 1.5 1.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.1 0.0 0.3 0.2 0.3 0.3 0.0 0.0 0.3 0.0 0.1 0.0 0.3 C4orf47 LOC441054 ENSG00000205129 "Chromosome 4 open reading frame 47" A7E2U8 4 185426249-185449826 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 24.3;fallopian tube: 13.6;retina: 15.1;testis: 13.3" "Cell type enhanced" "Detected in many" "Early spermatids: 191.3;Endometrial ciliated cells: 50.0;Excitatory neurons: 36.6;Respiratory ciliated cells: 106.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 2.4;hTERT-RPE1: 4.9;U-87 MG: 5.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA043662, HPA063485" Enhanced Uncertain Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA043662: AB_10964715, HPA063485: " "unprognostic (3.38e-2)" "unprognostic (2.66e-1)" "unprognostic (5.78e-3)" "unprognostic (2.84e-3)" "unprognostic (3.61e-3)" "unprognostic (1.31e-1)" "unprognostic (5.82e-5)" "unprognostic (3.72e-2)" "unprognostic (4.62e-2)" "unprognostic (2.84e-1)" "unprognostic (1.25e-1)" "unprognostic (8.71e-3)" "prognostic unfavorable (4.75e-4)" "unprognostic (1.05e-1)" "unprognostic (3.64e-2)" "unprognostic (9.88e-3)" "unprognostic (1.50e-1)" 0.5 0.3 3.2 0.2 4.4 0.3 2.1 3.8 2.9 1.0 24.3 0.3 0.1 1.2 3.8 0.3 13.6 0.9 0.9 3.3 3.6 2.7 0.4 2.0 0.1 7.2 8.2 0.7 0.7 0.6 2.9 0.2 5.5 0.6 0.2 15.1 0.5 0.6 0.1 1.0 0.2 0.3 7.1 0.2 0.3 13.3 3.9 0.2 4.6 0.1 0.2 0.3 0.3 3.9 2.4 0.0 0.2 1.2 0.4 2.3 0.7 0.0 0.1 0.2 0.3 0.3 1.4 0.1 0.4 0.1 0.2 0.2 0.3 0.4 0.5 0.5 0.4 0.0 0.1 0.3 0.5 0.0 0.1 0.5 0.5 0.5 0.2 4.9 0.0 0.5 0.3 0.1 1.8 0.3 0.0 0.0 0.3 0.0 0.9 0.0 0.0 0.2 0.7 0.0 1.3 0.6 0.4 0.0 1.5 0.5 0.1 0.4 0.7 0.4 0.1 0.0 0.0 1.0 0.0 0.0 5.9 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.2 0.0 0.0 3.2 4.4 3.8 2.9 3.3 3.6 7.2 8.2 5.5 7.1 3.9 3.9 0.6 3.2 1.5 21.5 2.0 0.6 0.9 8.7 4.6 0.9 2.2 3.9 0.6 1.5 13.2 3.7 10.4 0.1 0.4 0.4 1.9 2.8 191.3 50.0 1.5 1.3 0.0 0.0 36.6 0.6 1.5 2.4 6.6 3.4 0.0 0.3 1.1 0.1 0.2 1.7 26.3 0.0 2.0 0.6 0.4 20.9 0.6 0.7 1.8 4.7 0.1 3.6 0.0 18.6 13.4 1.0 0.0 0.7 9.6 0.6 0.0 3.7 106.6 14.8 0.0 3.0 3.1 12.6 5.0 2.6 0.6 0.3 1.5 0.5 0.0 0.3 C5AR1 "C5A, C5AR, C5R1, CD88" ENSG00000197405 "Complement C5a receptor 1" P21730 19 47290023-47322066 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 125.5;lymphoid tissue: 84.8" "Group enriched" "Detected in many" 4 "Hofbauer cells: 130.9;Kupffer cells: 228.3;Langerhans cells: 122.4;Macrophages: 446.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 394.0" "Group enriched" "Detected in many" 42 "granulocytes: 394.0;monocytes: 115.9" "Cell line enhanced" "Detected in some" "A549: 3.9;CAPAN-2: 4.1;HMC-1: 4.7;U-87 MG: 6.2;U-937: 6.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB002720, HPA014520, HPA048012" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus" Vesicles "CAB002720: , HPA014520: AB_1846337, HPA048012: " "unprognostic (5.95e-2)" "prognostic favorable (4.71e-4)" "unprognostic (1.70e-2)" "unprognostic (1.25e-1)" "unprognostic (4.08e-2)" "unprognostic (1.11e-1)" "unprognostic (1.80e-2)" "unprognostic (4.41e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (9.55e-4)" "unprognostic (2.02e-1)" "unprognostic (9.56e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (1.96e-3)" "prognostic unfavorable (7.99e-4)" "unprognostic (1.82e-2)" "unprognostic (6.54e-2)" 72.7 18.2 3.3 84.8 3.1 125.5 8.5 2.4 9.0 11.8 21.6 9.8 2.5 7.5 1.4 8.3 23.9 38.8 11.7 3.9 8.2 9.7 18.0 43.1 11.5 8.9 6.9 5.0 8.9 4.8 51.8 31.8 8.4 5.3 4.2 4.4 5.1 2.5 1.9 2.3 5.8 28.1 5.7 38.2 7.2 2.6 10.5 7.1 3.6 5.8 4.3 37.1 4.6 11.6 1.0 3.9 0.1 0.1 0.7 0.2 0.6 0.7 0.5 0.2 0.1 0.2 4.1 0.3 0.7 0.9 0.4 1.4 0.2 0.5 0.2 0.7 0.5 0.1 3.8 0.6 0.4 1.5 4.7 0.3 2.2 0.4 0.3 0.6 0.0 0.2 0.2 1.7 0.1 1.1 0.2 2.5 1.2 0.2 0.3 0.2 0.1 0.3 1.3 0.9 0.0 0.0 0.3 0.3 0.6 0.5 0.2 2.2 0.0 0.1 2.1 0.3 0.1 0.2 0.3 0.3 6.2 6.5 0.2 41.6 53.8 38.8 0.4 80.4 0.3 0.4 0.3 0.2 6.1 0.6 0.3 0.3 394.0 0.5 115.9 1.1 0.3 19.3 3.3 3.1 2.4 9.0 3.9 8.2 8.9 6.9 8.4 5.7 10.5 11.6 4.4 3.2 20.8 0.0 5.1 5.1 1.0 3.4 2.8 1.0 2.1 4.4 2.9 1.5 15.3 1.8 2.1 0.8 1.5 1.6 3.9 0.0 1.3 17.3 1.8 6.3 0.0 0.4 1.5 0.0 1.5 5.3 1.1 4.6 25.2 0.1 2.9 8.3 130.9 0.0 0.6 0.8 4.1 228.3 122.4 1.3 0.6 446.7 5.4 5.6 56.3 0.2 0.0 1.0 0.3 0.1 0.1 0.0 4.9 0.5 0.7 1.3 40.7 4.3 13.1 4.1 2.8 0.5 0.9 1.4 3.0 1.5 3.3 0.0 1.3 0.5 C7orf61 IMAGE:4839025 ENSG00000185955 "Chromosome 7 open reading frame 61" Q8IZ16 7 100456620-100464260 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 68.4" "Group enriched" "Detected in many" 20 "Early spermatids: 588.7;Late spermatids: 349.4" "Cancer enriched" "Detected in some" 5 "glioma: 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "HUVEC TERT2: 25.2;NB-4: 9.6;TIME: 14.9" HPA060395 Enhanced Approved Vesicles NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 78: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA060395: AB_2684274" "unprognostic (1.88e-1)" "unprognostic (5.02e-1)" "unprognostic (1.26e-2)" "unprognostic (7.70e-5)" "unprognostic (1.65e-1)" "unprognostic (2.63e-2)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (4.26e-1)" "unprognostic (2.25e-1)" "unprognostic (4.43e-2)" "unprognostic (2.53e-1)" "unprognostic (6.39e-13)" "unprognostic (9.54e-2)" "unprognostic (2.93e-1)" "unprognostic (1.33e-2)" "unprognostic (1.24e-2)" 1.3 0.6 11.5 0.5 14.7 1.4 0.9 12.5 13.4 2.0 7.4 1.6 0.0 0.9 0.3 0.9 1.4 0.5 1.2 11.0 12.4 1.0 0.8 1.6 0.8 13.7 13.3 3.0 0.3 0.2 2.9 0.6 13.1 1.5 0.1 1.9 0.5 0.6 0.5 0.8 0.9 0.2 11.1 2.6 0.7 68.4 12.7 0.8 1.1 0.6 0.3 1.1 1.3 16.3 1.0 0.2 0.8 0.9 0.9 2.2 0.3 0.4 1.5 0.2 0.8 1.1 0.5 0.7 1.7 0.9 1.4 0.7 0.3 0.0 0.6 1.0 1.7 1.4 2.2 0.0 1.2 0.5 0.4 0.3 0.4 0.9 1.4 2.4 25.2 2.4 0.7 1.3 1.5 2.4 0.5 9.6 0.6 0.3 1.1 2.5 0.0 0.5 0.4 0.4 0.0 0.0 0.6 0.8 1.5 0.5 0.4 2.6 14.9 1.3 2.2 2.8 0.4 0.3 0.2 1.0 0.3 2.3 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.3 0.3 0.2 0.1 0.0 0.6 0.0 11.5 14.7 12.5 13.4 11.0 12.4 13.7 13.3 13.1 11.1 12.7 16.3 1.7 0.0 0.0 16.0 1.0 8.3 0.5 0.7 4.6 1.7 2.9 5.5 1.4 1.5 0.4 0.0 0.0 0.2 1.7 0.4 0.0 0.5 588.7 0.8 1.2 2.2 0.0 0.0 1.2 0.0 0.4 2.0 0.0 1.1 0.0 1.5 0.7 0.0 0.9 3.3 1.5 0.4 0.0 0.3 16.8 349.4 7.8 1.4 5.4 0.0 0.7 7.4 0.0 4.5 14.1 0.2 0.1 3.8 0.0 0.7 0.5 0.1 0.4 0.1 6.6 1.7 1.8 22.9 2.6 1.6 6.1 0.1 2.2 0.4 0.4 0.4 C8orf44-SGK3 ENSG00000288602 "C8orf44-SGK3 readthrough" 8 66667596-66860472 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Astrocytes: 17.3;Excitatory neurons: 23.5;Inhibitory neurons: 17.5;Microglial cells: 11.2;Oligodendrocyte precursor cells: 15.6;Oligodendrocytes: 18.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 31.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA006699, HPA027146" Approved Uncertain Nucleoplasm,Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles Nucleoplasm "HPA006699: , HPA027146: AB_1856745" 4.1 3.1 5.2 3.1 5.5 6.1 6.3 5.3 7.2 4.5 3.5 3.5 2.8 5.6 11.5 2.1 7.3 3.7 4.4 5.1 6.3 4.2 3.1 3.4 5.7 4.6 4.8 7.9 2.2 2.9 3.8 4.7 5.1 5.8 9.1 4.2 6.1 4.1 6.9 2.6 4.9 3.9 5.1 4.3 6.6 4.8 5.7 7.6 3.7 5.4 2.6 7.5 6.9 2.4 3.5 2.6 5.8 7.0 1.7 2.3 4.3 5.2 5.8 2.8 8.7 9.8 1.3 5.3 4.1 4.4 5.5 3.1 8.2 8.5 8.3 9.3 7.2 5.5 4.6 5.3 6.0 9.2 9.1 3.3 7.3 9.0 5.3 10.7 9.7 5.6 4.8 2.1 4.6 3.7 3.5 6.6 3.8 3.7 2.4 2.4 5.0 2.0 3.4 3.8 2.9 1.3 3.9 5.3 7.0 3.5 5.1 2.6 2.5 2.2 2.2 5.7 3.8 4.8 4.7 6.0 1.4 31.0 9.8 6.2 4.0 4.1 4.9 7.6 4.5 5.1 7.2 6.1 7.0 5.0 6.9 5.2 2.7 6.9 7.0 4.2 5.2 5.5 5.3 7.2 5.1 6.3 4.6 4.8 4.7 3.9 4.8 7.5 0.0 0.0 0.0 17.3 0.9 0.0 0.0 0.1 2.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 23.5 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 11.2 0.1 0.5 0.0 15.6 18.0 0.0 1.1 0.0 1.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.1 1.4 0.1 0.0 0.6 0.0 0.0 0.0 C9orf153 bA507D14.1 ENSG00000187753 "Chromosome 9 open reading frame 153" Q5TBE3 9 86220265-86259657 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 20.8" "Group enriched" "Detected in some" 26 "Early spermatids: 268.6;Late spermatids: 244.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in single" "HeLa: 1.3" "Not detected" "Not detected" HPA079466 Approved "Nucleoplasm,Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 34: Spermatids - Unknown function" "Nuclear bodies, Plasma membrane" "Nucleoplasm, Vesicles" "HPA079466: " "unprognostic (2.03e-1)" "unprognostic (1.79e-1)" "unprognostic (1.13e-2)" "unprognostic (2.33e-2)" "unprognostic (1.78e-1)" "unprognostic (5.30e-3)" "unprognostic (7.49e-2)" "unprognostic (2.75e-2)" "unprognostic (3.37e-1)" "unprognostic (6.85e-2)" "unprognostic (9.70e-2)" "unprognostic (1.49e-1)" "unprognostic (2.01e-6)" "unprognostic (9.43e-2)" "unprognostic (1.92e-1)" "unprognostic (9.64e-2)" "unprognostic (2.10e-1)" 0.1 0.4 0.3 0.4 0.2 2.6 0.2 1.4 0.9 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.4 0.1 0.2 0.2 0.1 0.1 0.2 0.5 0.5 0.6 0.2 0.1 0.1 0.0 0.9 0.6 0.1 0.1 0.6 0.2 0.2 0.0 0.3 0.2 0.1 0.0 0.2 0.3 20.8 0.5 0.1 0.2 0.1 0.0 0.0 0.0 1.3 0.2 0.8 0.0 0.4 0.0 0.4 0.3 0.2 0.0 0.0 0.2 0.0 0.6 0.8 0.2 0.2 0.5 0.2 0.0 0.0 0.1 0.1 0.3 0.0 1.3 0.2 0.1 0.2 0.2 0.1 0.6 0.1 0.0 0.0 0.3 0.9 0.0 0.5 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.7 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.6 0.1 0.2 0.4 0.1 0.3 0.0 0.1 0.4 0.8 1.6 0.2 0.3 0.6 0.1 0.1 0.1 0.1 1.2 0.2 0.1 0.1 0.5 0.3 0.2 0.2 0.1 1.5 0.3 0.2 1.4 0.9 0.2 0.2 0.5 0.6 0.6 0.0 0.5 1.3 0.3 0.0 0.0 9.8 0.1 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 268.6 0.4 0.5 0.7 0.0 0.0 4.8 0.0 0.1 0.4 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.4 244.8 2.8 0.1 1.8 1.0 0.1 0.4 2.1 6.6 9.7 0.1 0.0 0.7 0.4 0.3 0.0 0.1 0.0 0.1 0.0 1.3 0.7 1.8 1.9 0.0 0.1 0.1 0.2 0.3 0.1 0.2 C9orf72 "DENND9, DENNL72, MGC23980" ENSG00000147894 "C9orf72-SMCR8 complex subunit" Q96LT7 9 27535640-27573866 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Guanine-nucleotide releasing factor" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 127.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 24.3;classical monocyte: 32.0;intermediate monocyte: 44.7;myeloid DC: 25.2;neutrophil: 34.3;non-classical monocyte: 36.9" "Group enriched" "Detected in all" 8 "dendritic cells: 25.2;granulocytes: 34.3;monocytes: 44.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023873 Uncertain Supported "Vesicles,Midbody ring,Cytosol" "Intracellular and membrane" Yes NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 41: Macrophages - Immune response" "Vesicles, Cytosol" "Midbody ring" "HPA023873: AB_1845834" "unprognostic (1.78e-2)" "unprognostic (5.01e-2)" "unprognostic (7.63e-2)" "unprognostic (9.78e-3)" "unprognostic (1.46e-1)" "unprognostic (1.32e-1)" "unprognostic (1.59e-1)" "unprognostic (1.99e-3)" "unprognostic (2.45e-1)" "unprognostic (2.05e-2)" "unprognostic (2.16e-2)" "unprognostic (9.81e-2)" "unprognostic (1.44e-2)" "unprognostic (9.29e-2)" "unprognostic (1.10e-1)" "unprognostic (2.89e-2)" "unprognostic (9.13e-2)" 11.7 12.1 9.5 16.6 9.5 25.3 9.4 21.0 12.5 9.8 12.4 8.8 6.8 12.0 11.3 7.6 16.0 10.2 9.3 9.7 13.5 7.0 16.0 17.7 9.2 14.6 11.9 24.2 9.6 6.9 16.2 12.1 12.5 14.2 7.8 31.3 6.7 5.8 14.9 8.8 8.3 8.6 12.4 16.8 7.8 17.6 11.3 11.1 13.1 9.9 8.8 9.2 8.5 14.5 4.4 3.7 28.7 4.4 5.7 7.0 4.4 5.9 4.9 3.5 1.8 0.4 1.4 10.2 3.7 5.3 7.5 3.1 9.4 7.2 2.5 19.8 3.6 4.9 11.0 3.0 8.9 3.4 5.2 7.3 8.6 0.8 16.1 3.5 7.6 11.1 9.8 18.6 4.3 0.8 6.6 5.0 14.2 6.8 16.0 2.4 9.5 5.1 2.8 3.3 9.9 24.4 4.0 4.4 3.7 10.9 3.7 2.9 6.6 0.0 14.5 8.6 4.0 4.8 15.8 6.8 11.4 11.0 3.8 24.3 32.0 2.4 1.9 44.7 3.3 3.4 2.7 2.5 25.2 2.5 4.6 2.9 34.3 4.3 36.9 3.9 4.0 10.0 9.5 9.5 21.0 12.5 9.7 13.5 14.6 11.9 12.5 12.4 11.3 14.5 15.4 16.0 14.7 19.2 43.2 35.9 50.7 15.0 26.2 22.1 7.2 6.6 15.6 4.3 15.2 7.3 20.9 21.2 11.7 5.0 1.9 8.4 2.6 94.4 11.8 15.0 11.4 3.0 53.0 9.3 7.3 18.7 16.8 57.6 16.5 18.4 8.2 9.3 25.8 11.8 58.9 12.5 10.2 71.9 127.8 4.2 6.2 94.8 19.6 42.2 58.2 45.2 3.1 30.2 60.9 8.6 11.1 3.8 10.7 30.0 4.1 5.4 80.7 27.5 0.0 17.5 20.6 29.2 20.9 15.2 29.1 34.6 18.2 7.9 5.1 37.6 CA10 "CA-RPX, CARPX, HUCEP-15" ENSG00000154975 "Carbonic anhydrase 10" Q9NS85 17 51630313-52160017 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 54.9;cervix: 21.8;retina: 44.5" "Cell type enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 1607.5" "Cancer enriched" "Detected in some" 4 "glioma: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 1.2;RT4: 2.1;SCLC-21H: 6.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054825, HPA057837" Supported Approved Vesicles "Secreted in brain" NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA054825: AB_2682617, HPA057837: AB_2683542" "unprognostic (2.66e-1)" "unprognostic (1.76e-1)" "unprognostic (6.06e-2)" "unprognostic (2.10e-1)" "unprognostic (3.43e-1)" "unprognostic (8.22e-2)" "unprognostic (4.43e-3)" "unprognostic (1.02e-3)" "unprognostic (1.01e-1)" "unprognostic (5.91e-2)" "unprognostic (1.46e-1)" "unprognostic (7.21e-3)" "unprognostic (9.18e-5)" "unprognostic (1.60e-1)" "unprognostic (1.51e-1)" 0.0 3.2 22.9 0.0 21.0 0.0 0.0 54.9 27.2 21.8 7.9 0.4 0.3 0.2 0.0 0.0 0.4 0.1 0.0 23.0 20.6 7.2 0.0 0.0 0.0 33.4 19.3 1.9 0.2 0.0 3.9 1.0 33.4 0.0 0.1 44.5 1.2 0.0 0.0 0.0 0.5 0.1 19.5 0.0 0.1 10.2 30.6 0.0 0.0 0.0 0.0 0.1 0.1 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.2 2.1 6.2 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.9 21.0 54.9 27.2 23.0 20.6 33.4 19.3 33.4 19.5 30.6 17.6 0.0 0.0 0.0 8.8 0.2 0.0 0.0 0.0 0.0 211.9 0.0 0.0 0.4 0.0 0.0 3.7 4.2 0.0 0.1 0.0 15.6 0.0 134.5 0.0 0.0 0.3 0.0 0.0 343.6 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.0 17.0 0.0 0.0 0.0 0.2 84.4 1.2 0.1 0.0 14.0 0.0 5.1 0.0 1607.5 4.2 0.0 0.0 0.7 0.1 0.2 0.0 0.2 0.0 11.9 0.0 0.1 0.0 1.5 1.3 0.0 0.0 0.1 2.2 0.0 0.0 0.1 CA11 "CARP2, CARPX1" ENSG00000063180 "Carbonic anhydrase 11" O75493 19 48637946-48646187 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 330.0;choroid plexus: 146.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 81.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 46.1;hTERT-RPE1: 47.1;SCLC-21H: 32.6;U-266/84: 33.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041778 Approved Vesicles,Microtubules "Secreted in brain" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Microtubules" "HPA041778: AB_10794525" "unprognostic (1.39e-1)" "prognostic favorable (4.33e-4)" "unprognostic (2.59e-3)" "unprognostic (5.72e-2)" "unprognostic (1.54e-1)" "unprognostic (9.80e-3)" "unprognostic (6.02e-2)" "prognostic favorable (2.11e-5)" "unprognostic (3.79e-2)" "unprognostic (2.98e-1)" "prognostic favorable (8.60e-5)" "unprognostic (4.88e-2)" "unprognostic (8.64e-3)" "unprognostic (1.21e-1)" "unprognostic (7.15e-2)" "unprognostic (4.09e-3)" "unprognostic (1.75e-1)" 13.1 17.3 240.8 3.2 256.9 1.6 8.5 215.4 330.0 15.9 146.2 19.4 8.4 33.0 28.2 8.0 21.4 5.5 10.7 266.6 167.0 14.7 1.7 5.8 5.0 170.3 169.2 48.8 5.9 58.0 37.2 1.1 172.2 14.0 2.5 30.0 8.9 13.5 9.2 14.3 9.3 18.2 163.8 6.1 13.0 6.4 180.5 6.6 12.1 7.4 5.3 9.2 12.2 231.9 2.0 12.7 22.9 46.1 3.1 1.2 0.6 1.5 14.9 1.5 3.3 3.1 15.7 7.5 1.7 1.7 4.2 4.9 9.4 4.6 1.3 1.6 13.5 3.3 7.2 0.2 3.0 0.3 9.8 5.4 9.2 1.4 2.0 47.1 1.8 19.8 6.1 20.5 0.7 5.0 4.1 1.4 9.9 7.5 4.7 2.6 0.9 16.1 10.1 0.4 32.6 18.2 1.7 1.6 2.7 6.1 6.3 0.8 0.2 3.9 14.2 0.1 0.4 18.9 33.9 1.3 5.7 4.3 2.0 0.0 0.4 0.0 1.5 0.5 1.5 1.0 1.2 1.2 0.7 1.3 1.5 1.3 0.0 1.3 0.0 1.9 1.5 0.7 240.8 256.9 215.4 330.0 266.6 167.0 170.3 169.2 172.2 163.8 180.5 231.9 5.1 3.2 8.1 11.1 9.3 7.1 9.1 13.2 12.5 81.0 15.5 12.1 5.4 21.5 9.6 31.3 16.7 0.7 9.8 3.9 25.4 11.5 15.0 6.7 6.3 6.7 13.1 3.6 47.0 10.0 0.4 11.6 5.6 7.9 6.3 3.1 8.9 47.5 6.0 28.6 18.1 6.4 16.2 20.4 26.4 7.9 22.1 6.8 8.8 5.6 5.6 50.4 12.3 7.1 6.8 3.4 2.9 26.7 4.3 4.3 20.7 38.7 7.5 30.8 6.6 4.2 8.9 1.3 4.9 5.9 10.9 0.4 6.9 8.7 5.2 6.4 CA13 "CAXIII, FLJ37995, MGC59868" ENSG00000185015 "Carbonic anhydrase 13" Q8N1Q1 8 85220587-85284073 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 14.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 33.3;Proximal enterocytes: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 15.6;OE19: 30.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024689, CAB025567" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles NA NA 27000 "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Nucleoli "Nucleoplasm, Vesicles" "CAB025567: , HPA024689: AB_1846004" "unprognostic (1.12e-2)" "unprognostic (2.20e-1)" "unprognostic (1.75e-1)" "unprognostic (9.16e-5)" "unprognostic (2.21e-2)" "unprognostic (2.08e-1)" "unprognostic (9.39e-2)" "unprognostic (7.90e-3)" "unprognostic (1.97e-1)" "unprognostic (1.34e-2)" "unprognostic (3.58e-2)" "unprognostic (3.13e-1)" "prognostic favorable (9.40e-4)" "unprognostic (7.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.55e-2)" "unprognostic (3.00e-1)" 1.8 2.1 1.2 1.2 1.2 0.3 2.3 1.4 1.3 2.1 0.7 2.5 12.0 0.9 0.6 5.0 1.1 5.4 3.6 1.0 1.7 5.7 3.7 2.4 0.6 0.9 1.5 1.1 1.1 9.0 2.9 0.3 0.8 1.2 3.0 2.3 4.8 0.7 0.4 5.6 14.6 0.8 0.6 0.7 5.9 0.7 1.1 0.7 5.0 0.3 2.9 2.1 2.5 1.3 0.2 0.4 0.8 0.1 0.5 0.6 0.4 1.0 1.1 0.1 2.9 7.2 5.4 0.4 0.5 1.2 6.0 2.3 2.2 2.9 0.2 1.6 0.9 15.6 2.0 6.7 1.4 0.2 0.6 2.2 0.5 0.2 1.2 1.8 1.6 0.6 4.0 2.9 2.6 0.0 0.3 0.2 0.4 30.6 0.4 0.2 2.2 0.1 8.1 0.3 0.2 0.0 0.5 0.0 1.6 1.0 0.5 0.8 1.5 2.8 3.9 0.1 1.6 1.1 0.6 1.9 5.7 2.2 2.6 0.7 0.6 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.1 0.0 0.2 0.2 0.0 0.2 1.2 1.2 1.4 1.3 1.0 1.7 0.9 1.5 0.8 0.6 1.1 1.3 1.7 3.2 12.4 7.2 2.9 1.8 2.7 2.7 3.4 1.8 7.0 4.7 6.4 4.3 10.5 12.9 33.3 0.3 2.1 12.3 9.8 4.0 11.3 4.7 2.5 2.7 4.8 3.2 12.2 1.6 0.3 2.9 9.7 7.7 0.0 0.3 8.6 5.8 1.1 0.0 13.7 4.3 2.0 2.5 3.3 13.1 0.0 3.0 5.4 1.9 1.0 1.9 8.2 16.1 4.4 4.4 4.3 0.0 6.9 1.9 52.6 21.0 9.5 5.1 0.0 8.1 1.9 1.3 2.1 9.1 3.1 0.3 2.2 1.0 5.4 2.4 CA4 "CAIV, Car4, RP17" ENSG00000167434 "Carbonic anhydrase 4" P22748 17 60149942-60170899 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Lyase "Disease variant, FDA approved drug targets, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 263.6" "Group enriched" "Detected in many" 16 "Adipocytes: 704.2;Distal enterocytes: 1289.3;Paneth cells: 2368.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 7.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 99.5" "Lineage enriched" "Detected in single" 995 "granulocytes: 99.5" "Cell line enhanced" "Detected in single" "OE19: 1.1" "Region enriched" "Detected in all" 5 "cerebellum: 300.3" "Low region specificity" "Detected in all" "HPA011089, HPA017258" Enhanced Uncertain Vesicles,Cytosol NA NA 190000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Vesicles "HPA011089: AB_1845996, HPA017258: AB_1845997" "unprognostic (2.07e-2)" "unprognostic (7.85e-2)" "unprognostic (1.55e-2)" "unprognostic (7.78e-3)" "unprognostic (8.42e-2)" "unprognostic (1.19e-1)" "unprognostic (3.19e-2)" "unprognostic (5.84e-2)" "unprognostic (7.76e-2)" "unprognostic (9.74e-2)" "unprognostic (1.54e-1)" "unprognostic (1.71e-2)" "unprognostic (2.68e-3)" "unprognostic (8.59e-2)" "unprognostic (1.43e-1)" "unprognostic (2.45e-1)" "unprognostic (4.57e-2)" 83.0 2.3 17.8 3.1 18.8 19.5 80.9 86.8 34.2 12.7 13.9 263.6 3.8 6.0 51.9 1.0 5.0 38.3 55.2 22.8 13.9 47.6 0.7 87.2 0.6 13.4 17.8 6.2 31.8 16.9 15.7 8.6 22.8 8.2 172.6 0.1 10.4 36.9 30.5 3.8 11.2 2.7 12.7 16.0 10.0 1.3 15.1 1.6 74.6 42.3 0.1 6.2 5.6 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.1 0.0 0.0 0.0 0.3 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 99.5 0.0 0.0 0.0 0.0 0.1 17.8 18.8 86.8 34.2 22.8 13.9 13.4 17.8 22.8 12.7 15.1 14.9 704.2 0.0 2.4 1.3 1.5 1.5 0.3 0.0 2.2 0.0 2.3 2.5 9.1 0.0 0.6 14.7 0.0 0.0 1.2 1289.3 33.2 11.7 0.5 0.6 13.0 88.3 19.3 0.0 3.8 0.2 0.0 4.4 0.0 0.2 11.4 23.2 1.4 0.0 0.6 0.0 1.4 24.6 0.0 0.0 1.2 0.1 0.6 1.1 0.0 23.4 0.0 0.1 0.0 1.0 0.4 0.1 2368.3 0.0 1.2 0.1 14.9 72.4 0.7 0.0 6.6 5.0 23.4 0.1 0.0 0.1 1.1 0.0 2.4 0.4 41.7 0.3 CAAP1 "C9orf82, CAAP, FLJ13657" ENSG00000120159 "Caspase activity and apoptosis inhibitor 1" Q9H8G2 9 26840685-26892803 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA020404, HPA024029, HPA024100" Uncertain Approved Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA020404: AB_1845841, HPA024029: AB_1845842, HPA024100: AB_1845843" "unprognostic (1.07e-1)" "unprognostic (2.35e-1)" "unprognostic (1.73e-2)" "unprognostic (6.74e-2)" "unprognostic (8.83e-2)" "unprognostic (1.35e-2)" "unprognostic (4.79e-2)" "unprognostic (1.39e-1)" "unprognostic (1.11e-2)" "prognostic favorable (1.27e-5)" "unprognostic (1.46e-1)" "unprognostic (1.89e-1)" "prognostic favorable (7.94e-9)" "unprognostic (2.74e-2)" "unprognostic (7.57e-2)" "unprognostic (1.46e-1)" "unprognostic (1.43e-2)" 7.0 20.4 4.3 10.5 4.5 7.7 10.8 4.8 6.2 9.1 11.0 18.6 17.4 8.2 16.9 11.3 9.2 9.8 5.7 4.4 5.1 16.3 23.8 7.8 14.7 4.4 4.3 6.6 10.8 18.9 7.4 9.7 4.3 10.6 19.5 8.6 11.2 9.5 7.1 10.2 12.7 10.0 4.0 8.5 11.2 12.6 4.6 14.2 27.4 7.5 15.1 10.6 6.8 4.7 24.2 14.9 24.3 23.9 15.9 13.4 18.5 17.4 17.1 16.4 20.1 4.4 14.9 28.6 17.5 14.9 9.4 12.8 25.3 17.0 22.4 39.0 15.4 49.6 22.6 28.2 26.4 21.7 23.9 13.7 21.4 12.7 29.7 18.5 27.8 18.4 14.1 21.0 19.1 13.9 33.8 9.0 32.2 23.8 12.3 23.1 10.9 19.0 42.6 17.7 19.4 38.5 15.9 17.5 16.3 21.5 14.9 25.6 16.7 0.0 24.5 10.1 16.4 9.6 19.2 33.0 8.0 22.3 10.3 14.9 11.3 8.2 16.2 17.6 20.9 18.8 17.7 18.9 18.4 18.7 14.7 15.3 1.4 20.1 15.7 17.2 18.8 16.0 4.3 4.5 4.8 6.2 4.4 5.1 4.4 4.3 4.3 4.0 4.6 4.7 13.9 22.4 21.6 42.1 20.3 9.9 11.3 18.4 15.9 10.8 18.2 14.6 9.7 14.3 27.6 31.3 8.4 18.3 16.4 28.1 58.7 20.6 18.8 25.6 15.3 14.9 15.5 21.7 34.0 19.8 14.7 13.4 18.8 25.5 18.3 15.8 10.4 34.3 12.1 8.4 42.5 26.0 26.4 11.1 10.3 5.4 8.4 17.7 8.8 26.2 15.6 22.1 12.3 41.2 33.8 22.6 23.1 6.4 26.0 17.5 13.4 29.5 23.7 12.7 13.1 16.9 14.8 41.9 18.4 31.6 14.6 10.8 20.1 28.0 32.1 12.6 CAB39L "bA103J18.3, FLJ12577, MO2L" ENSG00000102547 "Calcium binding protein 39 like" Q9H9S4 13 49308650-49444064 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 200.0" "Cancer enhanced" "Detected in all" "prostate cancer: 28.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 41.8;RT4: 43.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003686, HPA045954, HPA076632" Approved Approved Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 15: RT4 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB003686: AB_426084, HPA045954: AB_2679512, HPA076632: " "unprognostic (3.90e-2)" "unprognostic (1.09e-1)" "unprognostic (4.13e-1)" "unprognostic (5.01e-1)" "unprognostic (3.29e-1)" "unprognostic (1.94e-1)" "unprognostic (2.82e-1)" "unprognostic (2.94e-2)" "unprognostic (2.78e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (3.08e-2)" "prognostic favorable (7.91e-4)" "prognostic favorable (1.94e-13)" "unprognostic (6.59e-2)" "unprognostic (8.31e-2)" "unprognostic (4.96e-2)" "unprognostic (8.05e-3)" 23.7 37.4 25.0 4.4 26.4 2.2 37.3 21.0 20.7 14.5 68.2 57.7 6.0 15.3 16.3 31.2 18.3 16.5 22.0 24.6 38.7 14.0 5.3 19.5 4.2 24.6 35.0 21.5 12.0 29.2 8.4 12.4 25.1 41.4 11.6 14.8 16.9 22.5 7.5 16.1 12.5 11.5 27.4 4.0 27.1 33.4 31.4 9.4 9.7 13.0 5.2 26.5 17.3 28.4 1.6 1.7 9.8 2.8 9.3 8.7 14.8 9.3 17.9 5.9 4.1 41.8 6.0 14.2 1.2 6.5 6.5 3.4 5.4 6.2 10.2 4.7 4.5 3.7 2.0 2.6 5.2 3.3 1.6 6.4 4.8 4.4 6.8 7.3 8.0 2.2 0.7 3.2 8.1 2.8 3.2 2.4 7.6 5.4 2.7 2.8 1.3 2.3 8.3 43.4 1.2 3.7 5.1 11.8 12.1 11.8 18.4 4.9 7.6 2.5 2.7 5.3 7.6 2.5 2.3 16.3 2.8 2.5 5.7 6.7 2.6 5.4 2.6 2.4 2.0 2.7 3.2 3.4 2.6 1.6 2.3 2.3 5.6 1.9 2.1 0.4 3.6 2.3 25.0 26.4 21.0 20.7 24.6 38.7 24.6 35.0 25.1 27.4 31.4 28.4 6.9 16.0 11.9 52.2 2.4 3.1 12.6 6.6 7.4 6.4 27.1 14.4 14.5 4.3 13.4 11.0 6.2 26.4 3.1 3.9 11.7 10.1 200.0 8.3 9.2 5.4 2.4 1.7 45.0 10.6 14.0 42.5 5.6 3.7 4.5 4.2 3.9 1.9 6.4 1.7 32.4 2.4 16.2 3.5 4.7 32.1 15.5 5.0 12.4 24.4 5.6 14.9 7.2 50.3 43.3 10.3 2.0 11.7 4.6 16.7 0.8 5.0 17.7 5.2 6.6 9.4 16.8 46.0 5.0 16.0 4.4 29.0 3.6 3.9 2.3 21.7 CACNA1H Cav3.2 ENSG00000196557 "Calcium voltage-gated channel subunit alpha1 H" O95180 16 1153106-1221771 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 107.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 22.8;Late spermatids: 15.5;Peritubular cells: 25.9;Sertoli cells: 26.3;Smooth muscle cells: 22.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 17.9;AN3-CA: 25.4;MCF7: 48.3;OE19: 16.0;T-47d: 13.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA039125 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Vesicles" "HPA039125: AB_10795578" "unprognostic (1.66e-3)" "unprognostic (2.10e-1)" "unprognostic (4.07e-2)" "unprognostic (1.21e-3)" "unprognostic (1.37e-2)" "unprognostic (2.15e-1)" "unprognostic (4.39e-2)" "unprognostic (2.38e-2)" "unprognostic (1.06e-1)" "unprognostic (3.30e-2)" "prognostic favorable (3.12e-5)" "unprognostic (1.66e-2)" "prognostic unfavorable (1.78e-5)" "unprognostic (1.93e-2)" "unprognostic (4.65e-2)" "unprognostic (1.70e-2)" "unprognostic (5.55e-2)" 13.6 28.0 13.6 5.2 24.5 0.1 7.6 2.1 12.1 26.3 0.0 107.7 6.4 57.3 2.6 7.1 37.8 10.3 9.3 11.0 8.1 14.1 13.4 11.8 0.7 3.0 3.8 80.1 4.6 3.6 45.9 2.1 2.9 28.0 2.4 1.8 1.9 27.5 6.2 19.4 22.3 15.6 3.7 0.7 27.5 19.4 13.5 0.5 11.0 3.0 0.2 57.0 17.1 0.2 0.0 17.9 3.0 25.4 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 10.4 0.1 0.0 11.0 3.0 0.0 4.5 0.3 0.0 0.0 0.0 0.0 0.0 3.0 4.9 0.0 0.0 48.3 0.0 0.0 9.4 16.0 3.6 0.0 0.0 0.2 4.7 0.0 0.0 0.0 0.0 0.0 0.9 1.0 13.9 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.6 24.5 2.1 12.1 11.0 8.1 3.0 3.8 2.9 3.7 13.5 0.2 1.3 0.0 0.0 1.0 0.0 1.5 0.1 0.0 0.0 22.8 0.3 0.1 2.7 4.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 3.7 7.2 0.2 5.3 2.2 10.8 0.0 2.6 0.0 0.1 1.3 0.5 0.2 4.5 0.0 0.4 7.8 0.1 0.0 0.7 1.0 2.0 0.0 0.3 15.5 8.4 0.2 0.0 0.0 0.0 0.8 0.0 0.5 0.1 0.4 0.4 25.9 0.0 7.2 0.0 0.7 0.0 1.5 26.3 0.4 22.4 3.4 5.1 0.0 3.4 0.0 0.2 0.3 0.1 1.3 CACNA2D2 KIAA0558 ENSG00000007402 "Calcium voltage-gated channel auxiliary subunit alpha2delta 2" Q9NY47 3 50362613-50504244 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 49.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Alveolar cells type 2: 182.3;Inhibitory neurons: 36.0" "Cancer enhanced" "Detected in many" "testis cancer: 20.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 8 "SH-SY5Y: 192.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034771, HPA071829" Enhanced Approved Vesicles NA NA 9700000 "Cluster 35: T-regs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA034771: AB_10603555, HPA071829: AB_2686454" "unprognostic (2.06e-1)" "unprognostic (2.37e-1)" "unprognostic (1.72e-2)" "prognostic unfavorable (7.62e-5)" "unprognostic (6.59e-2)" "unprognostic (6.37e-2)" "unprognostic (6.91e-2)" "unprognostic (6.57e-3)" "unprognostic (4.39e-2)" "unprognostic (1.17e-1)" "prognostic favorable (1.21e-4)" "unprognostic (2.71e-2)" "unprognostic (1.57e-4)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (3.55e-1)" "unprognostic (4.22e-2)" 1.0 0.6 4.7 1.3 5.2 1.2 1.2 9.9 6.9 1.4 0.3 1.6 1.2 1.6 0.9 0.6 1.1 0.7 8.4 0.7 13.9 2.3 0.3 49.1 1.2 8.3 8.4 2.1 4.3 2.5 7.1 1.8 14.0 3.0 1.9 8.6 1.3 1.1 1.8 2.6 1.6 1.2 4.8 1.4 4.1 6.5 11.4 1.0 2.2 1.5 0.5 0.5 0.7 2.1 0.0 0.1 3.0 6.6 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.6 0.0 0.6 0.2 24.8 0.0 0.1 0.1 1.8 0.2 0.2 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.2 0.4 0.0 1.1 0.1 0.2 7.9 0.2 0.5 0.2 0.0 0.7 0.0 0.0 18.6 192.7 0.6 0.4 0.0 5.5 1.5 0.0 0.0 0.1 1.8 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.7 0.0 0.9 0.7 0.9 0.7 0.0 0.5 1.2 0.7 0.0 0.9 0.0 0.1 1.2 0.4 4.7 5.2 9.9 6.9 0.7 13.9 8.3 8.4 14.0 4.8 11.4 2.1 0.4 76.9 182.3 4.2 0.4 1.5 0.4 0.0 1.8 21.5 2.5 1.7 4.6 0.0 2.5 1.8 20.9 0.0 6.8 0.8 0.0 0.2 0.7 0.1 0.4 0.6 1.2 2.7 7.8 0.0 0.0 1.5 3.1 0.2 20.3 0.3 0.4 0.0 0.1 0.0 36.0 11.0 0.0 0.0 0.4 4.0 0.3 0.4 0.0 1.9 0.1 4.3 15.5 6.0 0.9 0.4 0.3 1.9 2.9 0.7 0.2 0.7 2.2 9.8 13.1 2.4 2.4 2.6 11.2 0.2 0.6 0.3 2.9 3.4 0.6 0.3 CACNB3 CACNLB3 ENSG00000167535 "Calcium voltage-gated channel auxiliary subunit beta 3" P54284 12 48813794-48828941 "FDA approved drug targets, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 84.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 22.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.8" "Lineage enriched" "Detected in single" 10 "T-cells: 1.8" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 75.9;U-937: 109.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059515 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 32: U-937 - Innate immune response" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus, Vesicles" "HPA059515: AB_2684047" "unprognostic (1.77e-2)" "unprognostic (4.84e-2)" "unprognostic (2.16e-3)" "unprognostic (2.12e-2)" "unprognostic (8.76e-2)" "unprognostic (2.68e-1)" "unprognostic (2.06e-1)" "unprognostic (3.60e-2)" "unprognostic (3.27e-2)" "unprognostic (2.24e-1)" "unprognostic (5.67e-3)" "unprognostic (1.04e-1)" "unprognostic (5.44e-3)" "unprognostic (6.31e-3)" "unprognostic (6.58e-2)" "unprognostic (1.98e-1)" "unprognostic (2.78e-3)" 10.1 3.9 67.9 2.8 69.9 1.3 9.0 56.8 84.2 33.7 44.1 18.1 4.1 31.1 8.5 21.5 19.6 7.2 8.4 72.6 56.7 12.4 1.9 11.8 1.8 50.2 56.2 43.7 4.5 5.1 12.3 5.8 53.4 13.7 8.2 4.7 13.0 9.1 2.8 11.5 10.8 23.1 49.9 6.1 9.2 8.6 59.6 7.6 9.6 5.9 4.1 14.5 20.2 58.7 17.3 13.2 21.1 46.1 26.8 18.0 12.9 16.8 39.4 25.6 14.5 4.5 13.4 2.2 21.5 30.7 4.4 17.2 21.6 19.5 10.1 18.4 5.9 8.5 11.7 0.6 11.0 1.7 9.1 11.7 10.6 10.2 5.5 75.9 31.1 18.6 1.2 7.2 16.9 42.6 22.1 2.2 13.3 18.1 10.9 24.0 5.0 6.6 19.9 31.6 32.9 31.8 5.5 37.1 12.0 18.6 25.2 7.7 27.3 15.5 21.7 7.7 9.5 7.1 3.5 0.7 12.9 109.9 5.0 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.6 0.6 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.8 0.2 67.9 69.9 56.8 84.2 72.6 56.7 50.2 56.2 53.4 49.9 59.6 58.7 5.6 3.2 4.3 1.0 0.5 2.9 3.2 5.9 4.0 3.2 8.7 5.7 2.8 1.5 5.1 1.8 4.2 0.8 2.1 12.6 1.9 9.5 1.0 10.0 22.0 5.9 10.2 0.8 15.1 4.3 10.4 7.9 6.1 7.1 1.3 12.0 3.6 0.2 1.6 0.0 4.5 9.5 16.2 0.6 2.9 2.7 13.4 2.4 1.8 3.7 3.7 1.0 2.1 2.0 1.1 10.4 4.6 10.9 1.3 2.9 8.7 0.7 9.4 1.0 0.0 1.5 12.2 1.6 8.1 9.6 5.1 1.1 3.5 6.1 14.4 1.9 CACNG4 "MGC11138, MGC24983" ENSG00000075461 "Calcium voltage-gated channel auxiliary subunit gamma 4" Q9UBN1 17 66964707-67033398 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 35.1;prostate: 11.7" "Cell type enriched" "Detected in some" 6 "Oligodendrocyte precursor cells: 145.3" "Group enriched" "Detected in many" 5 "breast cancer: 30.3;glioma: 35.8;ovarian cancer: 14.8;prostate cancer: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 6 "SH-SY5Y: 387.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 118.1" "HPA005803, HPA065370" Enhanced Approved Vesicles NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Vesicles "HPA005803: AB_2667439, HPA065370: AB_2685480" "unprognostic (1.27e-1)" "unprognostic (3.16e-1)" "unprognostic (8.87e-2)" "unprognostic (1.05e-2)" "unprognostic (6.42e-2)" "unprognostic (8.64e-3)" "unprognostic (2.91e-1)" "unprognostic (7.08e-2)" "unprognostic (3.37e-2)" "unprognostic (3.85e-2)" "unprognostic (6.03e-2)" "unprognostic (3.87e-2)" "unprognostic (2.38e-10)" "unprognostic (8.57e-3)" "unprognostic (1.23e-1)" "unprognostic (8.71e-2)" "unprognostic (4.28e-1)" 0.5 0.8 26.5 0.1 35.1 0.0 5.3 6.9 26.8 0.4 4.2 0.8 0.2 0.5 0.1 0.2 4.2 0.4 0.2 14.5 17.9 0.2 0.0 5.7 0.0 11.7 16.7 0.1 0.4 1.2 0.3 0.7 15.0 11.7 0.1 0.7 1.7 1.3 0.1 0.5 0.1 1.1 14.3 0.0 1.5 0.2 29.6 0.0 0.1 0.0 0.0 0.4 0.7 9.5 6.4 4.1 15.6 0.0 0.0 0.0 4.4 0.0 0.0 1.4 0.0 4.6 0.2 0.0 0.2 0.0 41.2 64.1 0.1 0.0 0.0 0.0 0.3 0.0 1.8 3.7 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 34.5 0.1 0.3 15.7 7.3 0.0 0.0 0.4 8.7 0.0 11.1 15.8 387.4 3.6 10.4 0.0 38.1 38.5 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.5 35.1 6.9 26.8 14.5 17.9 11.7 16.7 15.0 14.3 29.6 9.5 0.0 3.2 1.3 0.0 0.0 0.0 1.1 0.3 0.0 0.2 6.4 3.4 1.3 0.0 1.4 0.0 0.0 0.3 0.1 0.6 0.0 0.1 2.6 1.0 0.2 0.1 7.7 0.0 1.8 0.2 0.2 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.7 0.0 3.4 0.0 145.3 0.3 0.7 0.2 0.0 0.0 2.6 0.0 0.0 1.9 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.7 CADPS "CAPS, CAPS1, KIAA1121, UNC-31" ENSG00000163618 "Calcium dependent secretion activator" Q9ULU8 3 62398346-62875416 "Plasma proteins, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.6;retina: 184.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 772.6;Cone photoreceptor cells: 627.6;Excitatory neurons: 830.8;Inhibitory neurons: 1152.7;Oligodendrocyte precursor cells: 266.9" "Cancer enhanced" "Detected in many" "glioma: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 11.5;SCLC-21H: 19.7;SK-MEL-30: 9.0;U-698: 13.2;U-87 MG: 20.5" HPA059328 Enhanced Supported Approved Vesicles NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA059328: AB_2683982" "unprognostic (3.46e-3)" "unprognostic (1.40e-2)" "unprognostic (1.61e-2)" "unprognostic (3.87e-2)" "unprognostic (1.14e-1)" "unprognostic (1.61e-1)" "unprognostic (2.21e-1)" "unprognostic (3.12e-2)" "unprognostic (9.27e-2)" "unprognostic (5.73e-2)" "unprognostic (2.08e-3)" "unprognostic (3.21e-1)" "unprognostic (4.20e-3)" "unprognostic (1.90e-2)" "unprognostic (2.04e-1)" "unprognostic (7.91e-3)" "unprognostic (5.35e-3)" 0.4 16.4 32.2 2.0 47.7 0.1 0.7 18.7 84.6 2.8 0.0 2.8 3.2 0.6 2.5 0.2 0.4 2.4 16.7 32.1 26.0 0.2 0.2 0.8 0.5 83.2 39.7 1.9 13.5 0.2 39.6 0.2 84.5 3.6 2.4 184.3 1.4 2.8 0.1 1.4 3.3 0.8 4.1 0.6 3.0 3.2 33.0 0.6 0.2 0.0 0.7 0.4 1.4 61.7 0.0 0.0 0.8 0.0 4.2 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.5 11.5 0.0 0.1 0.0 0.0 0.0 0.0 19.7 1.5 0.0 0.0 9.0 0.4 0.0 0.0 0.1 1.6 0.1 3.3 0.9 0.0 1.7 13.2 20.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.2 47.7 18.7 84.6 32.1 26.0 83.2 39.7 84.5 4.1 33.0 61.7 0.0 0.0 1.9 93.0 0.1 1.3 0.2 0.0 0.0 772.6 0.5 2.8 25.6 7.2 0.0 0.0 627.6 0.1 0.0 0.4 0.0 4.1 1.1 0.2 1.1 0.9 95.9 0.0 830.8 0.4 0.0 3.2 0.0 0.1 42.5 0.2 0.0 0.0 0.0 47.1 1152.7 5.0 0.0 0.0 1.6 2.1 15.2 0.0 8.8 30.0 0.0 21.3 0.0 266.9 27.0 0.9 1.3 2.6 0.0 0.3 0.7 0.1 0.0 64.7 0.0 3.2 1.2 0.2 0.7 0.0 0.1 0.0 0.4 36.9 1.8 0.2 CADPS2 CAPS2 ENSG00000081803 "Calcium dependent secretion activator 2" Q86UW7 7 122318411-122886759 "Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 96.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 682.7;Microglial cells: 180.8;Oligodendrocyte precursor cells: 111.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 96.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 43.5;Karpas-707: 56.3;OE19: 63.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 159.9" HPA056398 Approved Nucleoplasm,Vesicles NA NA "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "HPA056398: AB_2683117" "unprognostic (1.93e-1)" "unprognostic (5.05e-2)" "unprognostic (1.91e-1)" "unprognostic (3.67e-3)" "unprognostic (8.69e-3)" "unprognostic (9.13e-2)" "unprognostic (1.19e-1)" "unprognostic (1.33e-1)" "unprognostic (4.07e-1)" "unprognostic (4.33e-2)" "unprognostic (3.93e-2)" "unprognostic (1.30e-1)" "prognostic favorable (1.01e-7)" "unprognostic (9.93e-2)" "unprognostic (1.37e-1)" "unprognostic (2.71e-2)" "unprognostic (3.45e-2)" 10.3 21.1 9.2 4.5 16.3 0.1 18.3 96.2 30.9 29.8 5.8 10.7 12.6 35.0 30.3 4.5 11.0 15.6 10.2 14.2 14.4 38.3 13.2 18.0 3.5 4.9 40.1 9.9 26.0 12.0 13.8 6.0 7.9 19.4 10.7 7.2 48.3 18.5 2.4 4.0 10.0 21.7 6.2 6.7 20.0 4.0 17.4 4.9 18.3 7.8 3.8 9.3 8.5 18.7 0.0 0.1 3.4 0.0 5.1 5.2 0.3 0.5 13.5 2.9 13.4 0.1 12.6 0.0 0.0 6.4 0.4 0.1 0.4 1.9 1.3 0.0 11.1 4.4 0.1 25.1 16.9 0.0 0.2 5.5 2.4 2.3 1.7 11.8 43.5 0.0 0.0 56.3 0.2 30.9 0.0 0.1 12.6 63.6 21.4 0.0 0.0 23.2 0.6 14.3 20.5 0.0 0.6 24.4 1.2 3.2 9.5 0.1 12.5 4.7 3.1 0.1 8.9 16.8 0.7 0.0 18.1 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 16.3 96.2 30.9 14.2 14.4 4.9 40.1 7.9 6.2 17.4 18.7 29.3 9.6 43.9 85.2 3.1 2.2 7.9 7.3 10.2 0.6 36.7 22.4 12.9 11.5 14.4 40.5 0.0 0.4 0.5 4.3 17.6 4.4 8.5 4.8 13.5 24.7 4.8 0.0 682.7 11.1 0.5 13.0 42.3 11.2 1.3 10.1 14.3 12.5 0.4 3.3 14.2 13.2 10.2 3.1 1.4 6.8 9.6 0.6 3.6 180.8 0.0 27.2 0.0 111.1 11.0 4.8 3.7 10.1 15.7 13.4 5.7 7.9 9.4 1.5 0.0 6.9 6.2 0.7 4.2 6.2 1.4 0.3 0.7 11.3 8.0 8.5 CALB1 CALB ENSG00000104327 "Calbindin 1" P05937 8 90058608-90095475 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 320.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 26.1;Collecting duct cells: 27.6;Cone photoreceptor cells: 91.8;Distal tubular cells: 31.3;Horizontal cells: 99.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.8" "Group enriched" "Detected in many" 6 "granulocytes: 2.8;monocytes: 1.4" "Cell line enhanced" "Detected in many" "A-431: 134.9;EFO-21: 189.8;HeLa: 65.9" "Region enhanced" "Detected in all" "cerebellum: 430.7" "Group enriched" "Detected in all" 4 "basal ganglia: 49.7;cerebellum: 119.6" "CAB002138, HPA023099, HPA056734" Enhanced Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" Vesicles "CAB002138: AB_563448, HPA023099: AB_1845859, HPA056734: AB_2683220" "unprognostic (2.19e-1)" "unprognostic (2.28e-3)" "unprognostic (2.61e-2)" "prognostic unfavorable (1.60e-4)" "unprognostic (1.82e-1)" "unprognostic (5.39e-2)" "unprognostic (2.05e-1)" "unprognostic (1.27e-1)" "unprognostic (3.49e-2)" "unprognostic (1.37e-2)" "unprognostic (7.36e-2)" "unprognostic (1.59e-1)" "unprognostic (9.01e-2)" "unprognostic (2.11e-1)" "unprognostic (7.88e-2)" "unprognostic (2.24e-1)" "unprognostic (1.42e-1)" 2.4 1.6 7.4 2.0 31.3 1.3 1.7 63.0 21.1 5.5 0.0 1.7 3.2 1.2 3.4 8.5 1.9 1.4 0.9 9.2 14.0 320.6 2.6 3.6 0.9 16.8 10.4 1.2 2.5 2.2 8.4 3.9 6.3 0.8 2.5 54.1 1.7 0.5 1.9 3.5 2.7 1.3 15.9 1.3 2.3 3.6 32.1 2.7 2.5 0.3 1.2 0.5 0.1 7.8 134.9 6.1 30.2 1.2 1.1 4.9 4.0 2.0 5.8 0.7 1.1 2.9 15.1 0.5 189.8 0.1 0.8 47.8 46.0 54.6 9.1 0.3 2.5 3.2 65.9 0.7 5.3 0.8 4.4 1.5 17.3 2.5 25.4 7.0 36.1 2.6 9.9 3.4 35.9 0.6 1.9 0.1 45.3 2.9 17.9 1.3 1.2 3.9 12.9 0.7 5.0 2.9 38.2 2.3 0.6 45.8 1.7 1.1 0.1 3.9 28.1 6.6 11.9 3.1 3.9 1.0 0.5 0.9 0.2 1.5 0.2 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.8 0.0 1.4 0.3 0.0 0.4 7.4 31.3 63.0 21.1 9.2 14.0 16.8 10.4 6.3 15.9 32.1 7.8 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 26.1 0.0 0.1 1.5 0.0 0.0 27.6 91.8 0.0 0.0 0.0 31.3 0.0 14.9 0.0 0.1 0.3 3.5 0.0 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 99.3 14.7 0.0 0.0 0.0 0.0 1.7 0.9 0.0 0.0 0.0 0.0 15.8 0.0 1.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 12.8 0.0 0.3 0.4 0.3 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.1 CALCOCO1 "calphoglin, Cocoa, KIAA1536" ENSG00000012822 "Calcium binding and coiled-coil domain 1" Q9P1Z2 12 53708517-53727745 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 109.6;hTERT-RPE1: 146.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038313, HPA038314" Approved Enhanced Vesicles,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 55: Plasma cells - Humoral immune response" Cytosol Vesicles "HPA038313: AB_10675794, HPA038314: AB_10672587" "unprognostic (2.28e-1)" "unprognostic (1.62e-1)" "unprognostic (3.11e-2)" "unprognostic (8.42e-2)" "unprognostic (3.03e-1)" "unprognostic (3.63e-2)" "unprognostic (1.30e-1)" "unprognostic (9.66e-2)" "unprognostic (3.31e-2)" "unprognostic (1.83e-1)" "unprognostic (2.62e-2)" "unprognostic (1.71e-2)" "unprognostic (2.85e-3)" "unprognostic (8.01e-2)" "unprognostic (2.80e-1)" "unprognostic (5.63e-3)" "unprognostic (9.88e-3)" 125.7 71.3 81.0 25.0 92.7 35.0 115.3 93.5 100.3 102.4 95.0 163.1 31.0 105.3 69.1 71.2 101.7 55.6 142.9 82.0 81.9 73.8 57.0 98.3 33.8 85.2 81.4 110.9 108.3 65.6 80.2 50.3 87.1 90.6 35.4 47.6 119.8 55.5 264.2 180.8 88.3 53.2 78.1 91.0 126.5 49.5 82.7 36.3 89.2 120.6 37.5 125.0 96.4 88.7 12.1 13.8 20.4 26.8 109.6 71.5 13.1 26.4 56.2 19.4 26.6 6.7 52.7 4.9 23.7 61.3 10.0 15.8 8.2 22.3 20.7 20.1 17.1 9.9 31.5 5.4 53.3 4.2 22.0 99.8 58.2 20.3 19.8 146.7 35.2 22.0 8.1 46.7 34.2 5.2 13.5 15.9 4.2 10.9 15.1 13.6 11.3 17.2 31.9 8.4 11.7 21.0 15.1 8.3 26.7 42.5 24.6 13.0 41.2 10.0 13.0 9.5 3.8 42.5 12.8 1.8 46.1 4.9 12.8 85.2 19.6 76.7 26.1 22.4 18.7 14.5 17.8 20.8 11.6 17.1 15.7 17.6 72.0 20.2 23.7 8.8 33.4 23.8 81.0 92.7 93.5 100.3 82.0 81.9 85.2 81.4 87.1 78.1 82.7 88.7 33.0 35.3 14.4 18.9 19.8 32.4 19.0 16.7 30.1 34.3 32.8 27.6 11.7 25.8 16.8 22.0 35.5 23.8 26.0 13.6 5.9 16.7 40.7 27.1 19.4 23.4 28.6 32.0 31.1 11.7 8.8 29.2 16.8 17.5 7.6 29.1 31.8 17.9 15.9 26.9 33.3 18.7 24.4 26.0 15.3 54.0 47.5 28.6 19.6 11.2 21.9 25.3 64.9 20.6 22.6 22.0 17.5 41.3 53.5 20.1 25.9 14.0 26.5 44.6 19.7 28.6 29.5 24.2 9.3 16.7 50.7 45.6 27.3 27.5 13.0 26.4 CALCOCO2 "MGC17318, NDP52" ENSG00000136436 "Calcium binding and coiled-coil domain 2" Q13137 17 48831018-48866522 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Early spermatids: 1127.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA022989, HPA023019, HPA023195" Enhanced Supported Vesicles,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol Vesicles "HPA022989: AB_1845914, HPA023019: AB_1845915, HPA023195: AB_1845916" "unprognostic (3.71e-1)" "unprognostic (2.87e-1)" "unprognostic (3.84e-2)" "unprognostic (3.37e-2)" "unprognostic (4.90e-2)" "unprognostic (4.46e-2)" "unprognostic (2.05e-1)" "unprognostic (2.28e-1)" "unprognostic (3.88e-1)" "unprognostic (2.15e-1)" "unprognostic (2.41e-1)" "unprognostic (4.03e-2)" "unprognostic (3.52e-2)" "unprognostic (1.06e-1)" "unprognostic (3.80e-2)" "unprognostic (7.57e-2)" "unprognostic (5.65e-2)" 117.9 59.2 36.5 55.3 43.8 62.9 95.3 41.6 50.8 81.0 72.3 101.0 68.1 69.2 61.0 88.6 82.2 66.2 139.1 35.3 45.3 75.7 120.3 91.4 53.2 48.7 42.0 86.6 56.6 76.8 46.6 63.3 49.2 55.6 101.5 76.4 52.5 72.5 158.4 68.2 75.4 87.8 39.0 68.8 71.6 136.3 41.0 74.4 75.3 170.3 67.1 80.9 76.9 52.0 126.0 79.4 33.1 64.0 241.2 173.7 95.0 120.2 160.0 135.9 151.3 150.8 80.6 42.5 117.0 146.5 115.9 68.2 81.4 101.7 162.6 193.3 66.9 40.7 48.0 59.1 276.8 137.4 196.8 258.1 148.1 144.3 103.9 129.0 101.3 130.7 74.9 124.3 119.2 36.8 119.5 73.6 10.3 278.9 97.7 77.8 161.7 81.0 52.2 39.2 13.1 27.9 37.6 24.3 106.0 66.6 154.2 76.5 97.7 147.1 44.9 91.0 85.8 110.4 165.1 30.0 89.2 69.0 61.4 108.9 115.1 115.5 56.6 121.5 54.2 54.1 49.9 58.9 67.1 46.7 50.5 55.8 132.8 105.0 132.3 33.6 107.2 89.7 36.5 43.8 41.6 50.8 35.3 45.3 48.7 42.0 49.2 39.0 41.0 52.0 166.2 115.4 98.1 20.5 42.1 36.6 73.3 40.9 40.9 16.8 34.7 32.4 169.1 37.1 48.4 33.1 50.1 50.2 48.6 124.5 37.2 47.2 1127.4 37.4 89.7 104.6 50.4 40.8 31.0 42.2 45.3 79.1 31.6 44.0 100.0 29.8 110.3 58.9 27.6 8.4 21.2 44.7 24.4 119.2 54.3 233.3 70.2 70.7 26.6 28.1 57.4 45.9 64.9 26.7 27.3 37.7 54.6 74.1 56.2 57.6 81.5 48.9 28.4 72.7 72.3 69.6 76.2 152.5 32.7 55.6 46.9 81.3 54.6 96.3 66.1 66.1 CALCR CTR ENSG00000004948 "Calcitonin receptor" 7 93424486-93574730 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8;kidney: 1.5" "Cell type enhanced" "Detected in some" "Early spermatids: 16.5;Late spermatids: 7.7;Microglial cells: 15.9;Skeletal myocytes: 46.0" "Cancer enriched" "Detected in single" 5 "renal cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 1.6;SuSa: 2.9;T-47d: 2.7" "Group enriched" "Detected in many" 5 "basal ganglia: 6.3;hypothalamus: 24.6" "Low region specificity" "Detected in all" "HPA028962, HPA061428" Enhanced Supported Approved "Vesicles,Cell Junctions,Centriolar satellite" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 6: T47d - Mammary gland" "Cluster 50: Fibroblasts - ECM organization" "Cell Junctions" "Vesicles, Centriolar satellite" "HPA028962: AB_10602339, HPA061428: AB_2732661" "unprognostic (1.95e-1)" "unprognostic (2.43e-1)" "unprognostic (3.88e-2)" "unprognostic (1.88e-1)" "unprognostic (1.55e-2)" "unprognostic (3.43e-1)" "unprognostic (7.73e-5)" "unprognostic (1.64e-1)" "unprognostic (9.24e-3)" "unprognostic (8.70e-2)" "unprognostic (1.86e-2)" "unprognostic (6.68e-2)" "unprognostic (2.71e-3)" "unprognostic (1.46e-3)" "unprognostic (1.69e-1)" "unprognostic (2.49e-4)" "unprognostic (1.05e-2)" 0.1 0.2 1.6 0.0 0.5 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 5.8 1.5 0.0 0.2 0.0 1.8 1.6 0.2 0.0 0.0 0.1 0.6 3.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 2.1 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 0.0 2.9 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.5 0.0 0.2 0.0 5.8 1.8 1.6 3.4 0.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 1.1 0.0 0.0 0.8 0.6 7.7 0.6 0.6 0.0 15.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.0 0.0 3.4 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 CALN1 CABP8 ENSG00000183166 "Calneuron 1" Q9BXU9 7 71779491-72447151 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adrenal gland: 11.3;brain: 44.3;lymphoid tissue: 24.7" "Cell type enhanced" "Detected in some" "Astrocytes: 88.8;Excitatory neurons: 130.6;Inhibitory neurons: 212.7;Oligodendrocyte precursor cells: 44.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "Karpas-707: 44.5" "Low region specificity" "Detected in all" "HPA036278, HPA036708" Approved Uncertain "Vesicles,Plasma membrane" No No "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "Plasma membrane" "HPA036278: AB_10673125, HPA036708: " "unprognostic (6.38e-2)" "unprognostic (1.11e-1)" "unprognostic (2.87e-1)" "unprognostic (1.32e-2)" "unprognostic (2.02e-1)" "unprognostic (1.13e-2)" "unprognostic (3.67e-4)" "unprognostic (3.16e-1)" "unprognostic (1.29e-1)" "unprognostic (1.57e-2)" "unprognostic (1.41e-1)" "unprognostic (2.43e-1)" "unprognostic (1.83e-2)" "unprognostic (3.53e-2)" "unprognostic (1.23e-2)" "unprognostic (7.72e-4)" "unprognostic (2.99e-1)" 0.1 11.3 12.2 0.0 18.5 0.6 0.2 44.3 15.0 1.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.0 25.4 40.6 0.0 0.2 0.0 0.0 27.9 17.0 0.1 1.0 0.0 0.5 0.0 30.2 0.2 0.1 1.9 0.0 1.1 0.0 3.5 0.0 0.0 15.2 0.0 0.0 3.2 8.3 24.7 0.1 0.0 0.0 0.0 3.2 26.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 44.5 0.0 0.0 0.1 0.0 6.0 0.0 0.0 7.1 0.0 0.8 0.0 0.0 6.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 7.2 0.1 0.0 7.0 7.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 18.5 44.3 15.0 25.4 40.6 27.9 17.0 30.2 15.2 8.3 26.5 0.0 0.0 0.0 88.8 0.0 2.3 0.4 0.0 0.0 3.8 0.0 0.6 5.6 5.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.8 0.1 0.1 0.3 0.0 2.1 130.6 0.0 0.0 0.2 0.0 0.4 0.0 0.0 1.4 0.4 0.1 0.0 212.7 1.5 0.0 0.3 0.7 7.0 0.0 0.1 0.0 14.0 0.0 0.2 1.0 44.7 15.7 0.0 0.1 0.7 0.0 0.2 0.0 0.1 0.0 0.8 0.0 6.1 0.2 8.8 12.8 0.0 9.8 0.1 0.2 0.2 0.1 0.1 CAMLG "CAML, GET2" ENSG00000164615 "Calcium modulating ligand" P49069 5 134738495-134752157 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Host-virus interaction, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 845.6;Late spermatids: 1655.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052636, HPA056472" Approved Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "Nucleoplasm, Nucleoli" "HPA052636: AB_2681893, HPA056472: AB_2683143" "unprognostic (9.23e-2)" "unprognostic (8.54e-2)" "unprognostic (2.95e-1)" "unprognostic (2.21e-1)" "unprognostic (1.07e-1)" "unprognostic (1.07e-2)" "unprognostic (3.68e-2)" "unprognostic (5.41e-3)" "unprognostic (3.07e-1)" "unprognostic (8.54e-2)" "unprognostic (5.34e-3)" "unprognostic (4.58e-2)" "prognostic unfavorable (1.09e-5)" "unprognostic (3.26e-2)" "unprognostic (1.43e-2)" "unprognostic (2.19e-1)" "unprognostic (3.16e-1)" 52.3 37.2 50.6 17.5 52.1 31.7 42.1 50.7 69.4 57.0 48.2 54.8 34.4 45.8 48.2 29.5 45.3 27.4 26.9 52.3 55.9 29.7 29.3 28.6 26.2 51.9 53.8 68.6 30.7 27.0 43.1 17.9 54.3 34.9 15.9 29.1 29.0 31.8 60.4 36.7 30.4 28.5 52.8 26.1 36.5 51.3 52.1 25.8 27.0 35.6 25.3 44.2 41.1 53.3 27.5 22.2 33.0 64.1 76.3 118.3 14.4 39.0 55.8 26.8 52.8 38.9 40.1 113.9 56.2 27.5 42.7 34.2 29.2 46.9 35.0 54.3 54.5 29.9 33.2 32.8 56.3 13.7 89.2 96.9 49.5 35.1 57.9 92.3 54.8 49.0 18.6 47.1 39.9 31.2 43.1 58.2 17.1 34.7 21.5 46.2 40.7 44.3 46.0 26.4 52.2 36.9 27.1 15.3 97.1 40.8 48.4 33.9 53.2 24.5 16.4 40.2 35.2 45.8 55.1 42.5 46.2 48.5 14.8 62.0 26.4 60.7 30.5 31.8 41.1 43.5 43.5 38.4 29.1 39.5 45.0 44.2 47.9 31.4 44.6 26.1 52.6 31.6 50.6 52.1 50.7 69.4 52.3 55.9 51.9 53.8 54.3 52.8 52.1 53.3 86.8 38.5 36.4 13.7 92.9 167.1 107.0 113.6 157.1 80.5 121.9 124.7 45.1 100.1 68.9 42.3 25.0 50.3 93.3 42.8 92.0 63.9 845.6 57.6 116.4 99.5 62.4 76.6 29.4 90.9 62.5 107.4 32.6 61.7 123.4 66.6 102.4 69.1 69.9 55.5 32.0 69.4 107.8 111.5 130.8 1655.8 168.0 76.6 96.0 10.3 126.9 127.7 90.6 15.1 18.6 67.5 58.0 132.4 55.2 148.6 158.2 199.1 51.3 71.4 98.6 119.5 109.7 241.5 68.6 119.3 201.6 73.2 101.6 67.9 90.9 107.9 CAMTA2 KIAA0909 ENSG00000108509 "Calmodulin binding transcription activator 2" O94983 17 4967992-4987675 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Late spermatids: 54.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027835, HPA051147" Supported "Nucleoplasm,Vesicles,Actin filaments,Mitochondria,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Vesicles, Actin filaments, Mitochondria, Cytosol" "HPA027835: , HPA051147: AB_2681362" "unprognostic (2.82e-1)" "unprognostic (3.06e-1)" "unprognostic (1.11e-2)" "unprognostic (1.01e-3)" "unprognostic (1.10e-1)" "unprognostic (3.24e-2)" "unprognostic (2.36e-1)" "unprognostic (4.71e-2)" "unprognostic (2.78e-2)" "unprognostic (7.08e-2)" "prognostic favorable (6.00e-8)" "unprognostic (3.42e-2)" "unprognostic (9.02e-2)" "unprognostic (3.73e-2)" "unprognostic (1.20e-1)" "unprognostic (4.56e-2)" "unprognostic (1.19e-1)" 15.8 15.6 10.7 13.6 15.9 10.3 15.0 5.2 36.7 14.8 0.0 19.6 10.3 17.0 4.4 14.4 14.4 8.7 17.7 24.2 3.4 16.0 12.9 18.4 9.7 10.0 4.4 14.8 17.5 19.2 26.0 7.4 8.5 15.1 10.8 10.7 13.9 11.6 38.0 17.4 19.0 14.2 0.5 21.6 18.6 14.5 7.3 10.4 17.0 27.5 9.5 16.0 13.0 18.4 13.2 23.2 4.2 6.1 27.8 19.0 8.6 12.4 13.8 11.6 10.1 5.9 3.6 15.5 11.9 19.7 9.8 13.1 16.2 19.5 6.6 21.8 20.7 9.8 13.3 6.6 15.9 5.8 40.4 13.4 24.0 10.8 17.1 14.0 19.6 11.8 16.2 13.9 11.0 8.8 10.3 3.7 0.6 15.6 9.5 8.9 4.8 6.1 13.1 13.8 5.8 5.1 7.8 14.1 3.8 7.2 12.6 5.6 25.6 9.1 5.3 9.8 20.6 6.8 8.0 5.6 22.4 11.5 9.2 0.5 1.2 0.9 1.3 1.6 1.0 0.6 0.6 1.2 0.7 0.4 0.8 1.0 3.0 0.6 4.9 1.1 0.5 1.4 10.7 15.9 5.2 36.7 24.2 3.4 10.0 4.4 8.5 0.5 7.3 18.4 15.2 3.2 11.3 11.4 9.2 6.9 3.7 11.6 8.6 14.7 11.9 8.9 8.0 12.8 6.9 11.0 10.4 5.9 9.0 16.1 1.9 7.9 30.1 5.9 12.6 10.0 11.4 7.4 17.9 11.2 9.6 12.3 20.4 11.6 13.3 14.7 16.8 15.3 8.5 35.3 15.7 13.9 20.3 16.7 10.2 54.3 10.2 13.1 3.6 4.7 14.9 6.5 12.3 9.0 9.5 10.6 13.9 9.4 9.0 6.3 20.1 15.4 6.1 11.2 13.1 7.9 14.8 7.2 6.9 8.8 10.4 12.4 11.4 14.4 12.2 4.1 CAPN8 nCL-2 ENSG00000203697 "Calpain 8" A6NHC0 1 223538007-223665723 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "stomach 1: 291.1" "Cell type enriched" "Detected in many" 6 "Gastric mucus-secreting cells: 910.8" "Cancer enhanced" "Detected in many" "pancreatic cancer: 28.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "OE19: 125.9;RT4: 76.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA073939 Approved "Nucleoplasm,Nuclear membrane,Vesicles" No NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Nuclear membrane, Vesicles" "HPA073939: AB_2686646" "unprognostic (4.87e-3)" "unprognostic (2.58e-1)" "unprognostic (1.89e-1)" "unprognostic (2.06e-2)" "unprognostic (1.32e-2)" "unprognostic (1.49e-1)" "unprognostic (7.97e-3)" "unprognostic (1.19e-1)" "unprognostic (1.26e-1)" "unprognostic (8.08e-2)" "unprognostic (2.72e-3)" "unprognostic (3.55e-1)" "unprognostic (4.12e-6)" "unprognostic (6.95e-2)" "unprognostic (5.59e-2)" "unprognostic (3.83e-2)" "unprognostic (5.44e-3)" 0.3 0.2 4.7 6.3 1.0 0.1 14.9 0.1 1.7 1.1 2.3 23.6 8.0 0.1 11.1 0.6 1.3 14.3 0.0 2.3 3.6 1.7 0.3 21.3 0.1 2.7 1.5 0.2 2.9 0.0 0.1 0.3 1.1 2.9 33.0 0.3 8.5 1.4 0.8 2.3 4.6 1.1 2.0 0.3 291.1 0.6 1.8 0.0 0.2 0.0 0.3 12.3 0.7 2.5 1.5 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.8 0.0 4.6 0.0 0.1 0.0 0.2 8.3 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 1.0 0.2 0.0 0.2 125.9 3.8 0.1 0.0 0.0 1.3 76.8 1.2 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 4.7 1.0 0.1 1.7 2.3 3.6 2.7 1.5 1.1 2.0 1.8 2.5 0.4 28.9 131.7 1.6 1.8 0.1 6.5 1.9 0.0 0.0 19.9 7.9 2.6 10.0 55.9 25.8 0.0 0.2 0.2 90.9 0.0 3.8 2.3 2.0 0.3 0.7 3.0 0.0 0.6 21.6 0.0 0.3 910.8 2.1 10.8 5.2 0.0 0.3 0.6 0.0 0.1 61.9 4.1 0.0 0.8 6.7 1.8 1.8 0.0 0.0 0.0 0.0 1.0 0.0 0.1 36.1 42.6 3.4 3.5 4.0 2.1 1.5 15.0 0.0 0.0 0.3 0.8 0.4 1.0 0.0 0.0 0.1 1.4 2.9 21.2 31.2 CAPN9 "GC36, nCL-4" ENSG00000135773 "Calpain 9" O14815 1 230747384-230802003 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 22.2;stomach 1: 60.3" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 25.6;Gastric mucus-secreting cells: 93.8;Intestinal goblet cells: 71.8" "Cancer enhanced" "Detected in many" "pancreatic cancer: 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "OE19: 10.7;SCLC-21H: 14.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA020398, CAB033483, HPA062050" Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 4: Stomach - Digestion" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 27: Mucus-secreting cells - Mucin production" Vesicles "Golgi apparatus" "CAB033483: AB_1119945, HPA020398: AB_2670429, HPA062050: " "unprognostic (2.64e-1)" "unprognostic (1.20e-1)" "unprognostic (2.60e-2)" "unprognostic (1.09e-1)" "unprognostic (2.20e-1)" "unprognostic (2.49e-2)" "unprognostic (3.36e-2)" "unprognostic (2.30e-2)" "unprognostic (4.61e-2)" "unprognostic (3.44e-2)" "unprognostic (9.10e-2)" "unprognostic (1.60e-1)" "unprognostic (5.97e-5)" "unprognostic (1.51e-1)" "unprognostic (2.08e-1)" "unprognostic (4.60e-2)" "unprognostic (2.16e-1)" 0.0 0.6 1.4 0.9 2.2 0.0 0.4 1.3 1.2 0.4 0.0 13.7 6.6 0.2 0.5 0.2 2.5 0.6 0.4 1.1 1.4 0.0 0.0 7.5 0.0 2.1 1.7 0.6 0.2 1.0 0.0 0.0 1.8 0.6 22.2 5.0 11.3 0.1 0.2 0.1 11.7 0.5 1.9 0.0 60.3 0.2 1.7 0.1 0.1 0.1 0.0 2.0 0.1 3.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.1 0.0 0.5 10.7 0.0 0.4 0.0 0.0 0.0 0.1 14.7 0.0 0.0 0.4 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 2.2 1.3 1.2 1.1 1.4 2.1 1.7 1.8 1.9 1.7 3.4 0.0 25.6 3.0 0.3 0.1 0.0 0.6 0.7 0.0 0.0 0.6 0.3 6.0 0.0 3.2 0.0 0.0 0.1 0.0 4.1 0.0 0.2 5.2 1.5 0.1 0.1 3.0 0.0 0.4 0.2 0.0 0.4 93.8 0.5 2.5 0.1 0.0 0.0 0.1 0.0 0.4 71.8 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 3.6 1.7 5.0 0.0 0.2 0.5 3.3 0.1 8.2 1.7 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 2.1 1.5 CAPS2 ENSG00000180881 "Calcyphosine 2" Q9BXY5 12 75275979-75390928 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 11.8" "Cell type enhanced" "Detected in many" "Astrocytes: 85.5;Excitatory neurons: 133.8;Inhibitory neurons: 95.8;Oligodendrocyte precursor cells: 117.1;Oligodendrocytes: 102.6;Respiratory ciliated cells: 77.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA039542, HPA040004" Uncertain Approved Nucleoplasm,Nucleoli,Vesicles,Centrosome Yes No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli "Nucleoplasm, Vesicles, Centrosome" "HPA039542: , HPA040004: AB_10794758" "unprognostic (1.38e-2)" "unprognostic (1.21e-1)" "unprognostic (7.26e-2)" "unprognostic (5.10e-2)" "unprognostic (3.05e-2)" "unprognostic (1.55e-2)" "unprognostic (2.66e-1)" "unprognostic (2.36e-1)" "unprognostic (9.61e-2)" "unprognostic (1.24e-1)" "unprognostic (2.02e-3)" "unprognostic (1.01e-1)" "unprognostic (1.32e-2)" "unprognostic (3.07e-1)" "unprognostic (1.75e-1)" "unprognostic (4.52e-2)" "unprognostic (2.69e-1)" 1.0 1.5 1.2 0.3 1.2 0.5 1.4 1.7 4.0 1.2 8.8 1.0 0.6 2.0 3.7 1.3 10.0 1.3 2.3 1.1 3.1 2.7 1.8 2.4 0.3 5.5 4.3 1.6 0.9 3.9 2.5 0.1 2.5 2.0 0.6 11.8 2.4 1.3 1.7 0.9 0.6 0.6 2.7 1.0 1.3 3.8 2.3 0.6 4.0 3.2 0.3 0.7 0.7 2.6 0.7 2.1 0.6 0.1 1.0 0.7 0.0 0.4 0.1 1.1 1.2 0.0 1.0 0.2 1.8 0.3 0.4 0.5 0.0 1.0 0.8 0.7 0.3 0.9 0.4 0.0 0.0 0.1 0.0 0.3 0.5 0.9 0.2 6.8 0.1 0.7 0.2 0.3 1.5 0.0 1.0 0.8 0.3 0.0 0.3 0.0 0.0 0.1 1.5 0.0 1.2 0.6 0.1 0.0 0.6 0.1 0.7 0.3 0.5 1.0 0.5 0.2 0.1 0.1 0.0 0.0 0.9 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.3 0.0 1.2 1.2 1.7 4.0 1.1 3.1 5.5 4.3 2.5 2.7 2.3 2.6 3.3 9.6 2.8 85.5 1.7 1.8 2.6 2.9 7.4 1.5 3.1 3.0 8.2 1.5 11.5 5.5 4.2 1.2 0.9 0.4 5.9 1.1 35.8 24.3 2.1 2.3 0.0 4.6 133.8 1.7 0.6 4.8 4.6 0.9 0.0 6.0 3.3 2.4 0.5 1.7 95.8 1.3 2.0 1.6 1.7 14.9 6.2 1.3 0.0 46.9 0.1 6.7 2.1 117.1 102.6 0.6 0.3 7.2 2.5 1.0 0.5 3.5 77.2 22.4 0.0 3.8 3.8 8.5 1.6 4.1 0.6 0.3 1.6 3.3 0.8 0.6 CAPZB ENSG00000077549 "Capping actin protein of muscle Z-line subunit beta" P47756 1 19338775-19485539 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1188.8;Late spermatids: 3669.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031531 Approved Approved Nucleoplasm,Vesicles,Cytosol No No 6600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" Vesicles "HPA031531: AB_10603556" "unprognostic (7.52e-2)" "unprognostic (2.13e-1)" "unprognostic (5.25e-2)" "unprognostic (1.31e-2)" "unprognostic (1.45e-2)" "unprognostic (2.18e-1)" "prognostic unfavorable (1.85e-4)" "unprognostic (4.55e-2)" "unprognostic (7.70e-2)" "unprognostic (3.08e-1)" "unprognostic (4.15e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (3.57e-4)" "unprognostic (1.18e-1)" "unprognostic (2.41e-1)" "unprognostic (4.00e-1)" "unprognostic (3.78e-1)" 210.2 193.0 126.1 196.7 126.9 154.3 189.1 128.8 133.4 233.9 129.0 294.5 149.1 254.5 145.8 265.1 199.9 144.2 207.5 139.9 129.8 161.3 127.7 217.9 223.8 133.7 128.6 205.1 94.2 128.6 121.5 178.7 132.5 200.9 214.2 123.8 152.5 177.9 301.8 195.1 220.6 241.4 126.3 215.9 192.6 216.2 135.8 237.1 155.2 214.2 271.8 230.3 222.2 143.8 263.9 146.4 260.0 179.3 355.6 467.0 187.9 435.9 430.0 364.0 377.5 189.6 338.1 179.7 186.4 533.5 218.7 212.0 224.0 297.9 424.3 280.0 160.5 340.1 170.6 298.3 355.0 236.5 533.6 424.0 243.4 314.9 292.6 300.5 338.6 204.5 132.1 229.7 393.9 185.1 270.5 307.0 200.5 343.8 155.3 223.4 184.6 225.2 507.6 133.0 158.0 123.4 255.2 200.6 299.3 229.5 222.2 199.6 351.5 237.9 207.0 409.4 208.7 156.0 188.8 217.4 314.1 306.8 261.5 456.1 358.2 1077.5 304.0 542.3 265.0 266.1 318.5 329.4 362.3 203.7 263.5 293.7 576.3 196.7 703.0 199.1 404.2 597.6 126.1 126.9 128.8 133.4 139.9 129.8 133.7 128.6 132.5 126.3 135.8 143.8 197.7 99.3 68.9 52.9 160.3 156.3 282.8 263.0 103.6 93.9 106.9 117.7 87.6 112.9 143.5 101.2 41.7 338.0 247.5 301.7 297.4 322.1 1188.8 86.7 122.2 182.4 141.2 89.4 49.8 256.5 396.4 178.9 101.9 96.8 147.5 164.6 156.0 98.7 800.9 77.4 67.5 278.7 215.7 302.6 276.7 3669.8 232.7 311.2 144.1 124.6 561.5 151.1 338.8 42.7 64.9 349.6 295.2 302.4 103.4 206.8 235.6 251.2 122.6 93.2 243.3 97.8 262.6 119.0 81.5 150.3 182.7 342.2 268.2 197.9 193.8 280.5 CARD10 "BIMP1, CARMA3" ENSG00000100065 "Caspase recruitment domain family member 10" Q9BWT7 22 37490362-37519542 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.5;Ductal cells: 25.4;Endothelial cells: 24.8;Pancreatic endocrine cells: 39.4;Paneth cells: 27.6;Proximal enterocytes: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 56.5;U-2197: 82.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029359, HPA055612" Approved Approved "Vesicles,Intermediate filaments,Cytosol" No No "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Intermediate filaments" Cytosol "HPA029359: AB_10601354, HPA055612: AB_2682861" "unprognostic (9.12e-3)" "unprognostic (2.28e-1)" "unprognostic (7.51e-2)" "prognostic favorable (3.47e-4)" "unprognostic (4.54e-1)" "unprognostic (2.70e-2)" "prognostic unfavorable (7.73e-6)" "unprognostic (3.66e-2)" "unprognostic (7.70e-2)" "unprognostic (1.93e-1)" "unprognostic (2.16e-1)" "unprognostic (3.68e-2)" "unprognostic (2.78e-2)" "unprognostic (2.87e-2)" "unprognostic (4.34e-1)" "unprognostic (4.31e-2)" "unprognostic (9.69e-2)" 10.0 8.4 3.7 5.0 3.3 0.1 10.5 2.9 4.0 6.5 2.8 13.3 34.1 6.0 1.3 8.4 7.5 7.8 10.7 3.1 3.0 14.9 12.4 6.1 2.1 4.7 3.3 3.1 9.2 2.7 2.1 4.7 5.0 5.4 8.8 0.3 19.0 4.2 8.0 9.7 35.9 4.2 3.3 4.1 9.9 15.0 4.2 0.8 6.8 8.2 1.0 6.1 5.8 2.9 31.3 23.1 4.1 3.0 0.1 8.7 19.6 2.8 6.5 12.8 10.0 14.2 21.8 0.0 10.8 5.4 12.4 43.0 4.9 56.5 3.9 0.1 11.8 0.7 15.6 22.1 5.4 0.5 1.9 2.9 11.5 24.5 31.2 10.2 26.1 0.0 3.3 0.0 9.9 11.0 0.1 2.0 7.2 17.0 13.2 0.0 38.9 3.0 19.1 5.4 1.5 2.4 21.0 9.5 2.1 5.0 10.1 1.7 35.0 9.5 26.9 82.8 16.4 0.1 0.0 0.0 30.2 0.0 21.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 3.3 2.9 4.0 3.1 3.0 4.7 3.3 5.0 3.3 4.2 2.9 22.6 0.0 2.0 0.0 0.2 8.5 6.8 3.4 2.2 1.2 3.9 4.3 3.7 10.0 1.6 3.7 0.0 0.4 0.2 35.5 1.9 25.4 7.8 3.3 0.4 24.8 7.7 0.0 0.1 19.6 1.6 1.9 15.8 6.2 0.0 0.4 17.9 4.8 0.1 0.0 0.6 19.8 4.1 0.0 1.2 8.6 0.0 0.4 5.4 3.7 0.0 0.0 0.0 0.0 0.1 39.4 27.6 0.7 0.2 8.6 35.5 12.4 1.2 0.2 0.0 6.2 1.1 0.4 3.4 2.5 3.8 0.0 0.6 1.0 11.3 9.7 CARF "ALS2CR8, FLJ21579, NYD-SP24" ENSG00000138380 "Calcium responsive transcription factor" Q8N187 2 202912214-202988263 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 66.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034557, HPA043191" Approved Approved "Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Nucleoli fibrillar center, Cytosol" "HPA034557: AB_10601663, HPA043191: AB_2732503" "unprognostic (4.63e-2)" "unprognostic (3.11e-1)" "unprognostic (1.30e-1)" "unprognostic (1.93e-2)" "unprognostic (6.09e-2)" "unprognostic (8.65e-3)" "unprognostic (1.12e-1)" "unprognostic (2.13e-3)" "unprognostic (4.39e-2)" "unprognostic (1.10e-1)" "unprognostic (7.58e-3)" "unprognostic (1.08e-1)" "unprognostic (6.12e-2)" "unprognostic (2.00e-1)" "unprognostic (2.22e-1)" "unprognostic (1.09e-1)" "unprognostic (2.55e-2)" 4.5 5.3 4.2 5.7 8.6 5.4 7.7 6.4 5.1 5.9 2.5 5.2 4.5 9.4 9.9 5.5 6.8 6.0 4.9 4.4 5.0 6.8 4.5 5.1 8.8 5.9 6.0 7.9 3.9 7.8 5.1 4.7 6.5 6.7 6.0 16.1 4.6 6.4 4.5 7.4 4.9 6.6 4.6 7.5 6.0 21.5 5.5 9.4 10.6 5.4 7.8 5.7 5.0 12.3 2.5 2.4 6.1 5.4 4.5 9.5 4.7 3.7 4.7 3.8 3.4 2.8 6.2 3.8 1.6 4.3 4.6 4.5 3.2 2.7 4.3 3.0 1.7 5.9 3.0 1.7 3.8 3.5 2.9 7.8 5.2 3.3 8.6 9.6 2.3 13.9 2.5 15.5 5.9 4.9 7.2 5.6 2.6 1.6 3.5 5.1 4.2 3.1 6.9 2.6 4.3 4.6 4.0 2.2 1.7 7.7 3.6 6.5 2.7 7.1 1.8 4.6 2.4 13.7 8.4 4.2 6.1 4.1 4.4 1.4 1.0 0.8 2.2 1.9 2.4 2.0 2.2 2.1 1.2 2.4 3.1 2.2 0.4 8.8 1.1 1.9 4.7 0.6 4.2 8.6 6.4 5.1 4.4 5.0 5.9 6.0 6.5 4.6 5.5 12.3 5.6 9.6 15.7 28.7 14.6 3.2 3.9 5.5 5.2 33.5 6.7 5.5 6.6 7.2 14.1 14.7 18.8 4.2 9.2 2.7 11.7 4.4 19.0 7.1 5.0 5.6 1.8 7.6 21.5 2.4 9.3 7.4 5.6 2.9 20.3 19.6 8.2 3.2 3.9 26.9 25.0 4.7 6.1 8.2 3.7 16.7 10.8 4.9 1.8 16.9 5.9 9.6 18.6 39.2 66.1 2.9 3.2 9.4 4.0 2.0 9.5 5.8 17.7 31.1 6.6 7.1 5.6 37.2 8.6 4.4 2.7 1.8 10.2 10.5 6.2 2.7 CASP10 "FLICE-2, MCH4" ENSG00000003400 "Caspase 10" Q92851 2 201182898-201229406 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Apoptosis "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 71.3;NK-cells: 44.3;Paneth cells: 44.5;Plasma cells: 49.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 25.3" "Low region specificity" "Detected in all" "CAB003780, HPA017059" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 1: K-562 - Erythropoiesis" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Vesicles "CAB003780: AB_289592, HPA017059: AB_1846040" "unprognostic (4.01e-2)" "unprognostic (8.24e-2)" "unprognostic (4.80e-1)" "unprognostic (1.28e-3)" "unprognostic (4.74e-2)" "unprognostic (2.25e-1)" "prognostic unfavorable (8.54e-4)" "unprognostic (1.73e-2)" "unprognostic (1.48e-2)" "unprognostic (3.68e-2)" "unprognostic (1.91e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (6.05e-7)" "unprognostic (3.23e-2)" "unprognostic (2.19e-2)" "unprognostic (4.49e-2)" "unprognostic (1.38e-2)" 8.8 2.4 5.7 9.2 5.5 19.5 6.5 4.5 5.8 4.0 4.4 13.2 21.8 3.3 6.2 8.8 5.4 7.4 6.7 4.7 5.1 8.1 6.2 11.5 8.9 6.0 5.0 1.6 4.8 2.3 1.3 9.6 5.8 3.9 13.4 1.3 5.4 3.1 4.9 5.7 18.4 5.1 5.6 22.6 10.2 1.2 7.3 8.7 5.3 2.8 10.4 9.0 5.1 5.4 4.4 3.5 0.3 0.4 0.1 0.3 7.5 0.7 4.6 0.4 1.8 4.6 9.8 0.5 7.0 2.5 1.7 2.9 0.2 2.3 1.3 2.1 4.8 12.2 4.0 15.1 1.6 8.3 12.7 0.5 2.0 5.3 0.4 0.3 25.3 5.1 14.9 17.4 0.4 0.3 15.9 7.8 0.6 6.0 2.4 8.8 0.5 18.4 8.7 6.2 0.2 0.1 4.1 0.2 1.9 3.0 0.2 7.8 10.0 0.4 0.8 3.4 0.2 18.7 12.1 0.5 4.5 6.3 0.2 5.9 11.7 0.7 6.4 16.5 5.6 8.2 5.2 3.6 6.5 7.7 7.2 6.4 2.1 8.5 19.3 6.6 1.2 7.2 5.7 5.5 4.5 5.8 4.7 5.1 6.0 5.0 5.8 5.6 7.3 5.4 20.7 19.2 10.0 0.3 15.8 6.0 2.7 10.6 5.2 0.0 1.3 0.9 1.8 8.6 9.4 9.2 0.0 1.1 20.5 71.3 1.9 16.2 1.2 7.7 7.4 29.7 2.4 14.9 0.3 10.4 0.7 4.2 26.5 12.0 7.6 0.8 26.4 7.1 9.4 0.0 0.5 21.6 4.1 26.6 17.5 0.0 0.6 16.2 7.2 33.7 22.0 0.5 44.3 0.0 0.9 8.6 44.5 0.0 49.7 2.5 26.1 8.7 24.4 0.4 0.0 2.9 2.2 0.1 0.1 6.6 4.5 0.4 12.9 4.1 16.4 10.3 CAT ENSG00000121691 Catalase P04040 11 34438934-34472060 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrogen peroxide" "Mitogen, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1217.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 722.4;Hepatocytes: 443.4;Proximal tubular cells: 333.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 13 "eosinophil: 4736.8" "Lineage enriched" "Detected in all" 13 "granulocytes: 4736.8" "Cell line enhanced" "Detected in many" "HL-60: 391.4;THP-1: 321.2;U-937: 265.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001515, HPA051282, HPA055838" Enhanced Enhanced Vesicles NA NA 760000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "CAB001515: AB_384710, HPA051282: AB_2681419, HPA055838: AB_2682937" "unprognostic (3.62e-2)" "unprognostic (2.72e-1)" "unprognostic (3.59e-3)" "unprognostic (5.43e-2)" "unprognostic (4.44e-2)" "unprognostic (5.80e-3)" "prognostic favorable (9.67e-4)" "unprognostic (9.95e-3)" "unprognostic (3.22e-1)" "unprognostic (7.23e-2)" "unprognostic (3.34e-2)" "unprognostic (9.77e-2)" "prognostic favorable (1.96e-8)" "unprognostic (1.01e-1)" "unprognostic (7.31e-2)" "unprognostic (4.77e-2)" "unprognostic (6.59e-3)" 281.3 115.1 27.1 52.1 29.6 407.7 123.6 27.9 35.5 82.0 39.4 82.6 145.1 53.1 34.8 40.1 86.8 59.8 58.1 26.6 29.4 296.6 1217.3 163.2 58.4 35.2 29.4 46.7 86.3 43.2 13.6 78.0 34.3 66.8 71.3 9.8 83.7 64.0 103.8 70.6 136.3 59.4 29.6 78.6 74.1 11.4 29.5 74.9 122.6 136.6 56.7 105.8 39.9 40.8 31.7 34.3 24.5 38.9 233.2 100.6 52.3 39.3 49.8 43.3 47.1 19.7 30.9 78.3 37.5 79.2 63.9 73.9 42.3 42.9 47.3 68.8 38.8 65.6 34.0 113.7 27.6 391.4 31.1 54.5 29.3 13.2 5.1 59.9 53.2 46.2 139.3 31.3 55.1 30.2 81.1 77.4 0.1 148.7 82.6 56.5 117.9 64.9 120.2 117.2 13.1 19.8 44.5 70.6 60.0 0.0 101.4 321.2 38.3 25.9 24.9 65.4 23.8 25.0 15.2 16.8 51.3 265.6 19.3 256.5 324.7 4736.8 54.4 265.1 64.6 133.9 63.7 61.0 353.5 124.1 61.7 66.7 290.2 105.7 298.5 235.8 92.7 397.9 27.1 29.6 27.9 35.5 26.6 29.4 35.2 29.4 34.3 29.6 29.5 40.8 196.9 227.6 275.9 41.1 53.8 28.9 93.7 44.9 27.9 13.5 42.6 36.1 44.9 82.9 66.9 73.5 27.1 96.8 92.0 59.4 225.0 36.0 2.7 72.2 41.4 43.8 48.0 722.4 12.6 26.2 30.0 53.1 54.6 29.3 24.0 38.7 57.1 443.4 138.5 0.0 1.2 56.9 91.6 125.5 95.8 6.2 78.3 93.9 26.6 16.9 253.4 19.5 28.8 22.6 45.6 15.3 44.8 77.5 25.4 37.0 151.6 333.2 96.9 19.4 78.9 46.6 68.0 6.3 11.3 24.4 27.1 40.5 37.7 57.7 95.6 97.5 CATSPERB "C14orf161, FLJ14298" ENSG00000133962 "Cation channel sperm associated auxiliary subunit beta" Q9H7T0 14 91580696-91780707 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "pancreas: 10.7" "Cell type enhanced" "Detected in some" "Early spermatids: 22.9;Exocrine glandular cells: 10.9;Gastric mucus-secreting cells: 11.7;Glandular and luminal cells: 6.2;Pancreatic endocrine cells: 7.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.2;OE19: 1.3;U-937: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA035134 Uncertain Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 32: U-937 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA035134: AB_10671510" "unprognostic (2.69e-2)" "unprognostic (1.95e-1)" "unprognostic (1.16e-3)" "unprognostic (1.93e-1)" "unprognostic (7.04e-3)" "unprognostic (2.72e-5)" "unprognostic (1.81e-1)" "unprognostic (5.01e-3)" "unprognostic (1.81e-3)" "unprognostic (3.52e-3)" "unprognostic (2.30e-2)" "unprognostic (4.34e-1)" "unprognostic (8.99e-3)" "unprognostic (6.85e-2)" "unprognostic (8.31e-2)" "unprognostic (8.88e-2)" "unprognostic (2.71e-3)" 0.5 0.2 0.5 0.6 0.5 0.3 0.8 1.0 0.5 0.4 0.1 0.6 0.4 0.2 0.4 0.5 0.4 0.8 0.4 0.3 0.2 0.2 0.1 0.6 0.9 0.3 0.1 0.3 10.7 0.3 0.2 0.2 0.3 0.6 0.5 0.8 2.5 0.2 1.2 2.3 0.9 0.2 0.1 0.6 1.4 1.1 0.2 0.3 0.5 0.0 0.5 0.2 0.2 0.8 0.2 0.0 0.2 0.5 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.7 1.2 0.4 0.3 0.0 0.0 0.2 0.0 0.1 0.2 0.4 0.6 0.1 0.4 0.7 0.0 0.5 0.2 0.1 0.2 0.1 0.1 0.5 0.0 0.3 0.1 0.0 0.1 0.7 0.2 0.2 0.0 1.3 0.1 0.1 0.0 0.0 0.1 0.3 0.5 0.0 0.0 0.2 0.5 0.5 0.1 0.7 0.3 0.0 0.0 0.0 0.1 0.2 0.3 0.1 0.0 1.2 0.3 0.3 0.0 0.1 0.1 0.0 0.2 0.1 0.2 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.5 1.0 0.5 0.3 0.2 0.3 0.1 0.3 0.1 0.2 0.8 0.1 3.2 1.5 0.3 0.1 0.1 0.3 0.2 0.0 0.0 3.3 1.0 0.2 0.0 2.1 0.0 0.0 0.1 0.3 2.2 0.0 2.7 22.9 1.6 0.9 0.6 0.0 0.0 4.9 10.9 0.1 0.6 11.7 6.2 0.0 0.1 0.0 0.1 0.0 0.0 1.3 3.0 0.0 0.3 0.3 3.2 0.6 0.1 0.0 1.9 0.6 0.0 1.0 0.5 1.8 7.5 2.5 0.0 0.4 0.9 0.1 0.5 1.5 0.0 0.0 0.9 0.3 4.5 0.2 0.8 0.0 0.3 0.7 0.1 1.4 0.8 CAV2 CAV ENSG00000105971 "Caveolin 2" P51636 7 116287380-116508541 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 227.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 887.8;Basal keratinocytes: 484.0;Pancreatic endocrine cells: 447.4;Prostatic glandular cells: 428.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 114 "basophil: 97.0" "Lineage enriched" "Detected in single" 399 "granulocytes: 97.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 274.1;HBEC3-KT: 329.8;LHCN-M2: 341.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013488, HPA044810" Enhanced Approved Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB013488: AB_2533493, HPA044810: AB_2679098" "unprognostic (4.76e-2)" "unprognostic (3.91e-3)" "unprognostic (4.56e-2)" "unprognostic (2.91e-1)" "unprognostic (5.09e-3)" "prognostic unfavorable (5.80e-5)" "unprognostic (3.66e-2)" "unprognostic (2.27e-2)" "unprognostic (3.81e-1)" "unprognostic (3.34e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (6.32e-2)" "unprognostic (3.44e-3)" "unprognostic (7.84e-3)" "unprognostic (2.88e-1)" "unprognostic (2.42e-1)" "unprognostic (6.34e-3)" 227.4 9.9 8.8 18.7 10.0 0.9 75.6 9.1 13.0 64.2 6.5 41.4 11.3 35.8 23.1 43.6 30.3 72.2 153.0 9.1 8.6 17.1 41.4 161.3 8.8 10.4 9.1 36.2 28.2 5.9 5.9 93.2 10.2 32.0 16.5 16.9 24.5 32.4 23.4 47.6 17.5 42.8 10.1 52.3 19.8 15.6 10.9 9.4 108.4 37.8 7.3 45.0 36.8 10.9 230.3 61.7 2.9 0.6 103.9 111.5 4.9 157.7 184.4 51.9 45.9 11.8 274.1 0.2 181.9 165.7 160.9 217.4 2.9 329.8 72.9 0.6 16.9 2.1 45.6 0.1 64.4 0.4 1.1 66.7 185.1 70.4 143.5 84.1 173.5 0.1 11.8 8.9 341.1 13.1 0.1 0.3 3.0 7.6 41.7 2.6 76.0 3.1 190.1 7.0 0.3 0.2 120.5 4.3 30.1 32.4 0.4 1.6 240.9 0.5 31.6 101.3 52.6 9.7 0.6 0.8 20.8 0.2 111.4 97.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.8 0.1 0.0 0.2 0.0 0.5 8.8 10.0 9.1 13.0 9.1 8.6 10.4 9.1 10.2 10.1 10.9 10.9 313.9 887.8 89.0 0.3 2.0 484.0 306.6 341.8 121.8 4.8 27.1 65.7 223.9 164.5 207.3 40.5 4.2 15.3 2.1 1.9 35.2 279.1 25.7 5.1 27.6 235.5 1.8 4.0 1.9 100.1 128.2 66.2 2.0 9.8 2.5 9.8 144.2 42.4 4.9 0.0 1.1 12.9 107.8 6.1 48.6 18.2 94.4 5.4 145.9 12.2 2.1 223.3 0.0 5.5 1.0 447.4 1.4 194.1 3.5 428.5 7.9 4.3 48.8 8.0 190.7 44.4 198.9 4.8 1.5 45.4 282.0 12.4 5.9 199.6 4.8 202.5 CAV3 "LGMD1C, LQT9, VIP-21, VIP21" ENSG00000182533 "Caveolin 3" P56539 3 8733802-8841808 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cardiomyopathy, Disease variant, Limb-girdle muscular dystrophy, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "skeletal muscle: 182.7;tongue: 72.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 22.9;Early spermatids: 4.2;Sertoli cells: 6.6;Skeletal myocytes: 11.0" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "RH-30: 94.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017518, CAB018557, HPA054488" Enhanced Approved "Vesicles,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" Vesicles "CAB017518: AB_628860, CAB018557: AB_626814, HPA054488: AB_2682504" "unprognostic (1.79e-1)" "unprognostic (1.43e-1)" "unprognostic (1.40e-2)" "unprognostic (6.43e-2)" "unprognostic (8.79e-2)" "unprognostic (3.05e-3)" "unprognostic (8.38e-3)" "unprognostic (9.79e-2)" "unprognostic (1.36e-1)" 0.4 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 5.7 0.1 0.1 27.4 0.1 0.1 0.0 0.0 0.9 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 1.9 0.1 0.0 2.5 0.2 182.7 0.2 0.1 0.0 0.0 0.1 0.1 0.4 0.1 0.2 0.1 72.8 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.5 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 11.0 2.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 CAVIN1 "cavin-1, CGL4, PTRF" ENSG00000177469 "Caveolae associated protein 1" Q6NZI2 17 42402449-42423256 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Transcription termination" "RNA-binding, rRNA-binding" "Congenital generalized lipodystrophy, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 575.1;Alveolar cells type 1: 429.5;Breast myoepithelial cells: 154.9;Cytotrophoblasts: 159.8;Endothelial cells: 217.4;Smooth muscle cells: 211.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 1105.9;fHDF/TERT166: 796.6;TIME: 920.9;U-138 MG: 912.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049838, HPA074213" Supported Supported "Vesicles,Plasma membrane" NA NA 440000 "Cluster 11: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" Vesicles "HPA049838: AB_2680907, HPA074213: AB_2686674" "unprognostic (1.59e-1)" "unprognostic (4.46e-2)" "prognostic unfavorable (6.36e-4)" "unprognostic (1.56e-1)" "unprognostic (1.76e-3)" "unprognostic (6.33e-3)" "unprognostic (1.72e-1)" "unprognostic (1.04e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (5.92e-4)" "unprognostic (7.18e-3)" "unprognostic (2.36e-1)" "unprognostic (3.44e-3)" "unprognostic (4.24e-3)" "unprognostic (3.21e-2)" "unprognostic (2.07e-3)" "prognostic unfavorable (5.87e-4)" 397.8 65.3 42.6 69.1 47.2 3.7 295.3 55.8 40.9 239.9 50.6 314.0 30.8 344.3 56.8 101.0 207.5 78.1 220.9 35.4 49.7 66.4 21.0 202.8 30.0 68.8 55.0 162.5 28.4 26.5 34.8 151.3 60.1 181.5 50.7 3.6 84.2 215.4 144.8 161.9 104.1 242.3 53.5 109.0 132.8 22.6 47.2 16.6 112.4 92.7 24.0 255.4 192.3 58.0 315.9 264.8 5.5 69.8 342.3 409.6 6.9 1105.9 477.8 432.2 340.5 134.6 20.1 0.5 216.3 796.6 177.4 509.7 46.8 331.6 351.0 1.1 9.5 137.5 154.8 66.1 215.8 0.3 1.2 283.0 120.5 340.8 115.8 230.2 592.3 0.4 95.5 1.3 187.9 5.0 7.4 1.6 25.8 48.1 1.8 0.6 173.3 0.6 186.1 1.6 0.4 2.0 371.9 6.4 91.7 145.2 29.8 2.0 920.9 912.0 429.5 330.9 407.9 0.8 0.9 1.6 270.7 0.5 104.8 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 42.6 47.2 55.8 40.9 35.4 49.7 68.8 55.0 60.1 53.5 47.2 58.0 575.1 429.5 117.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 55.4 154.9 0.0 0.0 50.8 23.9 0.0 159.8 3.4 0.0 3.9 45.6 0.0 11.7 130.4 217.4 0.0 0.0 0.0 4.4 11.3 114.2 0.0 16.9 63.1 116.3 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.5 0.0 0.0 0.5 0.0 0.0 1.1 3.6 0.0 0.0 0.0 211.7 0.0 0.0 0.0 0.0 77.2 4.5 6.6 0.0 0.0 CBS HIP4 ENSG00000160200 "Cystathionine beta-synthase" P35520 21 43053191-43076943 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Cysteine biosynthesis" "Allosteric enzyme, Lyase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 174.9;pancreas: 99.0" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 2.3;Cardiomyocytes: 4.9;Hepatocytes: 3.6;Ionocytes: 2.0;Melanocytes: 5.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 51 "neutrophil: 5.0" "Lineage enriched" "Detected in single" 51 "granulocytes: 5.0" "Cell line enhanced" "Detected in many" "BEWO: 177.5;HAP1: 172.8;HHSteC: 224.1;MCF7: 197.7;RPMI-8226: 197.4" "Low region specificity" "Detected in all" HPA001223 Supported Approved Nucleoli,Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles Nucleoli "HPA001223: AB_1846112" "unprognostic (4.86e-2)" "unprognostic (1.48e-2)" "unprognostic (6.81e-2)" "unprognostic (1.12e-3)" "unprognostic (1.32e-1)" "unprognostic (1.12e-1)" "unprognostic (9.68e-4)" "unprognostic (3.62e-1)" "unprognostic (6.76e-3)" "unprognostic (1.06e-1)" "unprognostic (6.50e-2)" "unprognostic (2.13e-1)" "unprognostic (1.61e-2)" "unprognostic (6.73e-3)" "unprognostic (2.62e-1)" "unprognostic (1.92e-2)" "unprognostic (1.02e-1)" 6.6 2.8 42.5 1.0 39.5 0.2 3.4 58.5 55.3 12.3 29.3 4.8 3.0 4.5 0.0 2.0 5.8 1.2 7.7 41.4 40.3 3.8 174.9 10.2 2.7 42.5 44.6 30.3 99.0 2.5 8.8 1.2 42.7 12.7 0.9 2.5 19.9 1.1 1.1 2.3 7.0 2.3 38.4 1.7 16.5 2.0 48.1 0.7 17.4 1.2 1.4 11.6 6.2 45.4 30.0 17.0 31.3 113.4 48.9 31.5 177.5 39.5 10.0 15.6 15.4 53.7 1.5 0.1 19.2 67.2 0.3 1.5 172.8 13.2 3.1 0.0 20.5 12.3 73.1 63.8 224.1 7.9 19.1 21.7 1.4 16.0 16.4 13.2 38.6 85.6 138.7 118.1 11.1 197.7 16.1 0.1 20.3 65.7 29.4 0.0 0.2 197.4 0.5 15.5 57.8 85.1 78.5 5.4 44.4 18.4 27.0 91.2 5.4 0.8 42.5 0.3 4.8 34.8 30.2 41.2 19.0 11.0 53.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 42.5 39.5 58.5 55.3 41.4 40.3 42.5 44.6 42.7 38.4 48.1 45.4 0.2 0.0 0.5 0.7 0.0 0.4 0.0 2.3 0.0 0.2 0.5 0.1 4.9 0.0 0.6 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.2 0.0 0.0 0.1 0.2 0.8 1.2 0.0 0.1 0.0 0.1 0.0 3.6 0.2 0.0 0.0 0.0 2.0 0.0 1.4 0.0 0.9 0.2 5.4 0.0 0.0 0.5 0.0 0.0 0.0 0.4 1.3 0.0 0.0 0.2 1.7 0.1 0.1 0.1 0.0 0.3 0.6 0.0 0.6 0.0 1.0 0.1 0.1 0.0 0.2 0.1 CBSL ENSG00000274276 "Cystathionine beta-synthase like" P0DN79 21 6444869-6468040 "Enzymes, Predicted intracellular proteins" "Amino-acid biosynthesis, Cysteine biosynthesis" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "liver: 88.1;pancreas: 48.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 14 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 14 "granulocytes: 1.3" "Cell line enhanced" "Detected in many" "AN3-CA: 105.1;NTERA-2: 246.2;U-266/70: 75.7" HPA001223 Supported Approved Nucleoli,Vesicles NA NA 510000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 5: NTERA-2 - Transcription" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles Nucleoli "HPA001223: AB_1846112" "unprognostic (2.39e-1)" "unprognostic (1.54e-2)" "unprognostic (1.15e-1)" "unprognostic (4.78e-3)" "unprognostic (6.49e-2)" "unprognostic (1.42e-2)" "unprognostic (1.28e-2)" "unprognostic (6.62e-3)" "unprognostic (1.17e-1)" "unprognostic (3.62e-2)" "unprognostic (7.50e-2)" "unprognostic (1.10e-1)" "unprognostic (2.04e-1)" "unprognostic (3.17e-3)" "unprognostic (8.44e-2)" "unprognostic (2.46e-1)" "unprognostic (3.61e-1)" 3.8 1.2 0.9 0.8 0.8 0.1 1.7 1.6 1.3 7.5 0.3 2.3 2.0 1.8 1.4 1.0 5.6 1.0 4.4 0.6 0.9 1.6 88.1 4.8 0.1 1.3 1.6 14.7 48.5 2.2 4.4 0.8 1.1 6.1 0.0 1.1 4.6 8.9 0.6 1.2 3.7 0.0 0.6 1.2 8.2 1.0 1.6 0.2 12.3 0.0 0.4 5.0 3.1 1.3 0.1 0.0 36.3 105.1 0.0 0.0 1.4 23.3 15.2 8.9 29.3 0.2 18.2 0.0 0.1 0.0 17.1 12.1 0.2 13.5 5.6 0.0 35.4 0.0 0.0 0.0 1.0 0.0 16.1 12.8 51.5 0.1 23.1 0.0 0.2 0.8 0.7 41.5 0.3 0.0 18.9 2.6 246.2 0.5 0.0 0.3 0.0 0.3 40.5 0.0 38.7 58.5 0.0 3.4 44.9 0.0 0.1 0.1 0.0 2.7 0.0 17.3 4.4 75.7 29.6 0.3 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.9 0.8 1.6 1.3 0.6 0.9 1.3 1.6 1.1 0.6 1.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CC2D1B "Freud-2, KIAA1836" ENSG00000154222 "Coiled-coil and C2 domain containing 1B" Q5T0F9 1 52345723-52366205 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.4" "Lineage enriched" "Detected in all" 4 "granulocytes: 10.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027500, HPA031426" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 34: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Vesicles "HPA027500: AB_10600693, HPA031426: AB_2673876" "unprognostic (1.11e-2)" "unprognostic (1.06e-1)" "unprognostic (2.38e-2)" "unprognostic (2.50e-2)" "unprognostic (5.85e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (1.45e-5)" "unprognostic (3.39e-2)" "unprognostic (4.75e-1)" "unprognostic (1.75e-1)" "unprognostic (1.76e-1)" "unprognostic (1.70e-1)" "unprognostic (1.13e-2)" "unprognostic (2.63e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-2)" "unprognostic (1.87e-1)" 13.4 15.0 14.5 8.7 18.0 5.0 12.6 17.3 15.9 10.4 13.5 13.0 8.0 11.0 9.2 16.7 10.0 7.0 13.3 13.1 16.0 18.9 17.2 17.8 12.1 19.1 17.7 13.3 15.6 10.2 19.5 7.5 18.6 13.7 6.5 4.0 12.7 7.1 29.1 12.0 15.0 5.5 17.4 17.9 12.8 16.7 17.1 11.0 17.7 11.7 9.7 12.2 12.0 19.5 12.4 17.2 7.8 12.2 28.1 10.7 18.3 15.6 27.3 19.9 15.0 11.5 10.1 7.7 12.9 18.2 43.6 8.3 10.1 21.6 9.0 14.2 11.1 8.5 13.6 9.7 22.6 11.8 19.8 15.9 19.3 22.2 16.9 19.3 12.4 12.2 14.7 8.2 22.2 8.5 12.4 9.7 15.2 12.5 19.2 7.9 14.7 11.3 21.0 17.2 8.5 8.0 15.2 22.7 22.7 20.0 8.0 17.4 14.9 22.9 12.6 12.6 17.9 11.7 11.5 9.9 30.3 12.7 28.8 10.4 1.1 2.8 2.3 0.6 1.9 1.7 1.8 1.8 1.1 1.2 1.4 2.0 1.6 1.9 0.5 1.1 1.6 1.3 14.5 18.0 17.3 15.9 13.1 16.0 19.1 17.7 18.6 17.4 17.1 19.5 6.7 9.6 13.4 4.6 7.5 3.2 3.3 3.4 5.2 5.6 3.9 2.7 5.6 4.3 7.6 11.0 0.0 9.0 9.0 10.2 3.9 10.0 3.7 6.7 4.1 5.8 6.0 2.5 4.6 12.7 10.3 3.9 14.8 9.6 15.8 6.7 9.7 8.2 11.6 1.7 4.6 5.7 2.0 6.9 1.5 2.4 3.4 8.0 1.8 2.8 5.9 6.5 8.2 2.0 5.9 12.2 9.1 6.4 6.7 3.8 8.6 5.3 5.4 4.9 0.0 5.1 4.1 16.6 8.8 4.9 3.1 15.7 8.9 5.8 4.9 3.5 CCDC115 "ccp1, FLJ30131, MGC12981" ENSG00000136710 "Coiled-coil domain containing 115" Q96NT0 2 130337933-130342699 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034598 Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" Vesicles "HPA034598: AB_10601697" "prognostic favorable (7.59e-4)" "unprognostic (1.28e-2)" "unprognostic (1.10e-3)" "unprognostic (6.80e-3)" "unprognostic (3.23e-1)" "unprognostic (1.08e-1)" "unprognostic (4.20e-2)" "unprognostic (8.13e-3)" "unprognostic (2.63e-1)" "unprognostic (4.29e-1)" "unprognostic (2.87e-1)" "unprognostic (1.91e-2)" "unprognostic (1.19e-2)" "unprognostic (1.07e-1)" "unprognostic (7.83e-2)" "unprognostic (2.16e-1)" "unprognostic (3.16e-2)" 27.8 25.1 25.3 18.0 25.8 24.8 25.4 26.4 28.0 33.7 21.7 25.3 21.2 29.5 32.3 31.1 29.9 19.9 18.4 25.2 26.6 29.8 17.8 26.6 29.8 26.8 25.3 41.6 20.2 40.2 22.9 13.8 26.3 24.0 19.3 15.8 29.1 27.7 12.9 39.3 24.2 17.7 26.1 26.1 24.1 10.4 25.4 23.3 30.3 12.3 26.0 26.8 28.1 27.5 22.5 10.5 13.3 8.1 27.2 30.7 16.3 10.5 28.2 22.4 26.1 24.4 48.5 25.7 36.6 18.3 11.4 20.7 10.8 19.2 16.1 33.4 20.2 20.2 5.4 27.3 22.7 20.8 40.2 26.2 44.2 14.6 8.1 21.8 23.7 24.3 19.8 22.6 27.7 20.7 38.5 37.5 17.2 11.2 26.4 29.4 14.2 24.1 18.8 18.6 12.4 22.8 12.3 22.4 24.2 8.7 24.5 25.3 18.6 10.1 10.4 18.5 8.3 12.4 13.0 19.7 22.9 22.1 13.5 129.9 94.6 154.8 80.8 136.0 71.8 96.3 85.1 85.8 95.2 98.9 81.1 74.8 33.3 80.6 174.9 73.8 103.6 132.8 25.3 25.8 26.4 28.0 25.2 26.6 26.8 25.3 26.3 26.1 25.4 27.5 37.5 19.2 28.3 3.6 43.6 51.9 42.3 104.2 40.5 25.9 43.3 41.9 13.9 35.8 50.8 77.3 10.4 76.7 35.1 29.9 105.7 47.4 1.4 14.5 16.9 30.8 27.6 13.5 8.7 42.7 36.6 30.6 21.4 20.3 53.3 22.7 33.2 21.4 63.5 23.5 12.3 35.6 99.7 45.5 60.7 4.5 42.6 49.4 53.4 5.6 97.3 48.4 49.4 10.1 12.2 27.5 49.1 52.3 16.9 14.9 51.9 65.9 24.3 27.6 46.0 29.2 31.7 9.0 24.0 42.4 70.0 26.4 51.3 39.1 41.6 30.0 CCDC122 FLJ31846 ENSG00000151773 "Coiled-coil domain containing 122" Q5T0U0 13 43823909-43879740 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 148.5;Spermatocytes: 43.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-HME1: 10.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034233, HPA054995, HPA061456" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Nucleoplasm "CAB034233: AB_2228702, HPA054995: AB_2682665, HPA061456: AB_2684527" "unprognostic (1.74e-1)" "unprognostic (6.82e-2)" "unprognostic (1.07e-1)" "unprognostic (1.67e-2)" "unprognostic (1.39e-2)" "unprognostic (1.68e-2)" "unprognostic (1.30e-1)" "unprognostic (1.51e-1)" "unprognostic (5.28e-2)" "unprognostic (2.79e-2)" "unprognostic (1.30e-3)" "unprognostic (2.74e-1)" "unprognostic (1.16e-2)" "unprognostic (2.14e-2)" "unprognostic (3.79e-2)" "unprognostic (1.32e-1)" "unprognostic (6.75e-2)" 2.3 2.9 1.7 1.9 2.9 0.9 3.8 1.4 2.0 2.7 0.7 2.9 1.7 4.1 5.3 2.1 4.4 3.1 4.6 1.5 1.9 3.0 2.4 2.0 2.7 2.5 2.2 6.1 3.6 4.0 3.2 3.1 2.5 4.9 3.5 0.6 3.2 2.4 1.1 4.0 2.5 3.3 1.7 2.9 3.1 4.1 2.2 2.1 4.9 0.3 2.7 2.9 2.0 4.9 2.2 1.8 0.8 0.0 0.6 4.0 2.3 5.7 6.4 3.0 3.3 3.0 7.6 3.8 3.2 3.4 4.9 3.4 0.7 0.8 3.9 5.7 2.8 1.6 1.0 1.6 8.1 0.9 0.4 10.4 6.7 4.2 10.9 2.5 1.4 1.4 0.0 1.1 4.0 2.6 0.6 0.6 0.9 0.5 2.1 0.9 0.0 2.1 4.5 1.2 2.0 3.1 4.0 0.1 3.4 4.3 0.6 0.6 7.1 0.2 0.8 4.9 0.0 0.0 0.0 1.8 2.7 0.1 2.9 3.5 0.6 1.1 0.5 0.6 0.6 1.0 0.7 0.5 0.5 1.3 0.5 0.5 1.4 1.4 1.1 1.2 0.7 0.4 1.7 2.9 1.4 2.0 1.5 1.9 2.5 2.2 2.5 1.7 2.2 4.9 5.6 9.6 11.7 8.5 5.2 3.1 8.9 6.1 9.6 1.9 10.5 12.1 11.1 10.0 8.5 7.3 0.0 17.5 1.7 4.5 19.6 13.1 2.8 14.3 11.3 6.7 18.0 6.1 15.8 10.1 11.6 9.2 4.6 8.3 1.3 13.8 5.7 4.9 2.0 10.1 24.7 9.4 0.0 2.2 2.7 2.3 17.7 3.9 1.8 21.5 0.8 12.7 0.0 28.6 148.5 7.6 2.9 7.9 1.3 8.3 6.4 12.0 19.1 0.6 0.0 7.4 6.7 43.2 26.3 5.5 3.8 7.9 2.9 14.0 7.1 6.4 CCDC130 MGC10471 ENSG00000104957 "Coiled-coil domain containing 130" P13994 19 13731760-13763296 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056977 Approved Approved Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Vesicles "HPA056977: AB_2683297" "unprognostic (6.54e-2)" "unprognostic (5.72e-3)" "unprognostic (2.13e-3)" "unprognostic (1.27e-3)" "unprognostic (2.71e-1)" "prognostic favorable (7.83e-5)" "unprognostic (7.04e-2)" "unprognostic (1.25e-2)" "unprognostic (2.47e-1)" "unprognostic (9.69e-2)" "prognostic favorable (2.34e-4)" "unprognostic (2.06e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (1.09e-1)" "unprognostic (1.15e-1)" "unprognostic (1.94e-1)" "prognostic favorable (1.82e-4)" 24.4 20.9 17.3 20.5 21.1 23.1 26.2 18.3 24.8 30.4 21.2 24.8 17.1 27.3 3.6 22.5 28.9 11.7 26.8 17.3 20.7 26.9 24.7 27.2 23.4 22.9 20.1 37.5 25.8 13.1 28.9 15.0 22.1 27.2 7.5 13.4 24.3 10.6 28.2 26.4 29.6 10.9 17.9 31.3 25.0 20.4 21.2 16.5 32.6 11.6 12.2 25.5 27.1 28.7 14.9 10.1 19.3 19.7 12.5 9.7 11.9 15.6 13.2 14.3 13.5 9.5 10.2 12.6 11.3 12.5 11.4 14.4 8.9 8.0 4.6 21.6 26.2 9.7 34.3 14.5 24.4 9.5 24.9 13.8 17.3 17.6 12.0 15.2 16.6 23.2 9.9 22.9 9.0 11.1 25.8 21.1 13.2 7.7 20.1 22.1 9.4 17.1 11.4 16.8 11.8 15.5 10.0 10.4 25.0 9.7 8.3 22.5 13.7 23.2 9.6 27.9 20.4 36.5 14.8 10.3 20.2 22.6 16.2 18.3 12.9 20.3 13.2 11.3 16.4 15.2 14.2 14.1 13.1 18.0 13.0 14.8 13.5 14.4 15.2 10.8 12.8 11.3 17.3 21.1 18.3 24.8 17.3 20.7 22.9 20.1 22.1 17.9 21.2 28.7 25.5 9.6 17.9 21.5 29.0 13.4 15.4 20.2 15.4 30.3 18.6 18.4 14.5 8.6 18.6 29.5 27.1 17.3 31.4 25.6 7.9 17.6 40.2 22.7 24.8 22.4 18.7 16.0 19.8 15.7 19.1 19.5 53.0 26.9 24.6 34.9 17.5 10.8 18.0 26.9 24.9 18.1 24.4 18.6 33.8 24.4 19.0 21.9 24.9 15.0 24.9 26.0 17.5 14.1 30.3 18.1 25.5 17.0 27.3 12.8 32.1 18.9 23.0 41.7 26.3 16.6 23.6 35.5 20.3 19.2 15.6 35.0 31.0 31.8 17.5 11.0 CCDC136 "DKFZP434G156, KIAA1793, NAG6" ENSG00000128596 "Coiled-coil domain containing 136" Q96JN2 7 128790757-128822132 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Fertilization, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 87.6;retina: 52.5;testis: 185.7" "Group enriched" "Detected in many" 4 "Early spermatids: 780.2;Late spermatids: 2032.0" "Cancer enhanced" "Detected in many" "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-87 MG: 30.5;U-937: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010646, HPA071015" Enhanced Approved Approved "Nuclear membrane,Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 32: U-937 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "Nuclear membrane, Plasma membrane" "HPA010646: , HPA071015: AB_2686334" "unprognostic (2.07e-2)" "unprognostic (2.32e-2)" "unprognostic (1.29e-4)" "unprognostic (4.65e-2)" "unprognostic (4.52e-1)" "unprognostic (2.16e-1)" "unprognostic (1.66e-2)" "unprognostic (2.53e-1)" "unprognostic (5.43e-4)" "unprognostic (2.58e-2)" "unprognostic (8.44e-3)" "unprognostic (4.35e-1)" "unprognostic (1.18e-4)" "unprognostic (5.27e-3)" "unprognostic (4.85e-2)" "unprognostic (1.19e-1)" "unprognostic (8.93e-3)" 1.8 3.7 37.2 1.9 24.4 0.8 1.7 42.7 39.9 5.2 6.2 20.1 1.6 9.3 2.2 1.7 3.3 2.2 5.7 24.2 34.7 0.7 0.3 1.1 2.7 30.5 54.2 2.8 0.8 1.6 6.4 1.4 26.3 12.1 3.1 52.5 1.6 13.6 4.4 0.9 4.8 11.6 34.9 1.5 4.6 185.7 87.6 5.2 1.3 4.0 1.7 13.1 3.9 30.6 1.1 1.5 11.7 7.9 6.3 5.4 2.0 4.7 6.0 4.6 4.3 1.8 1.0 6.5 0.5 6.2 18.4 2.5 7.8 0.9 4.3 17.2 7.7 10.7 3.1 0.0 2.2 1.5 22.2 6.0 0.8 5.0 0.4 4.1 2.7 10.0 4.0 6.0 1.9 2.3 8.0 3.4 16.3 0.1 5.1 19.5 2.3 2.9 0.3 2.4 7.4 20.4 2.9 3.3 5.1 4.1 0.3 3.1 2.4 7.4 4.2 3.7 3.5 3.4 1.6 6.1 30.5 46.2 1.9 0.0 0.0 0.3 0.3 0.0 0.3 0.0 0.3 0.2 0.1 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 37.2 24.4 42.7 39.9 24.2 34.7 30.5 54.2 26.3 34.9 87.6 30.6 1.6 0.0 0.5 11.4 1.1 0.5 0.9 0.1 1.8 306.0 0.6 3.8 7.5 1.5 0.7 0.0 98.0 0.1 2.2 0.0 0.0 0.7 780.2 0.3 2.2 2.0 0.0 0.4 23.3 1.5 0.3 2.6 1.5 0.1 0.0 1.9 1.1 0.0 6.8 40.4 48.0 0.1 0.0 0.6 1.6 2032.0 18.0 2.3 0.0 10.3 0.7 22.5 2.1 28.6 13.3 0.6 0.1 7.5 1.1 0.9 0.0 0.2 2.0 20.7 6.6 1.6 6.1 321.9 17.2 0.1 0.4 0.4 3.4 0.3 0.0 0.3 CCDC144A "FLJ43983, KIAA0565" ENSG00000170160 "Coiled-coil domain containing 144A" A2RUR9 17 16689537-16777881 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 9.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 54.2;Early spermatids: 59.1;Rod photoreceptor cells: 49.4;Spermatocytes: 165.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "basal ganglia: 2.4;cerebellum: 7.6;cerebral cortex: 6.9;hippocampal formation: 4.9;white matter: 3.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 9.5;TIME: 8.5" "HPA022996, HPA047220, HPA047851, HPA066260" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 6: Brain - Smell perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Vesicles" "HPA022996: AB_1846136, HPA047220: AB_2679989, HPA047851: AB_2680182, HPA066260: " "unprognostic (8.54e-2)" "unprognostic (4.49e-3)" "unprognostic (1.07e-1)" "unprognostic (8.34e-2)" "unprognostic (1.10e-1)" "unprognostic (2.18e-2)" "unprognostic (1.57e-1)" "unprognostic (5.69e-2)" "unprognostic (6.95e-2)" "unprognostic (2.60e-2)" "unprognostic (2.73e-1)" "unprognostic (1.43e-1)" "unprognostic (2.54e-1)" "unprognostic (9.49e-2)" "unprognostic (3.32e-1)" "unprognostic (1.41e-1)" "unprognostic (1.74e-1)" 1.3 1.3 0.6 2.1 2.4 4.2 1.5 7.6 6.9 1.1 0.0 1.7 0.7 3.5 2.5 0.8 1.6 1.2 1.2 4.9 0.0 0.5 1.1 1.3 1.7 0.8 0.0 4.5 2.7 0.4 1.6 2.7 0.8 1.5 0.9 7.4 1.2 1.0 1.0 2.5 1.0 1.6 0.0 1.8 1.5 9.1 0.0 3.3 0.8 2.3 1.2 1.6 0.9 3.9 0.5 3.4 0.8 2.1 3.0 9.5 0.4 0.2 0.0 0.2 0.2 4.4 0.1 0.5 2.8 6.2 0.2 5.3 4.4 0.3 0.2 3.2 0.2 0.4 0.5 0.3 0.2 0.7 2.7 1.7 0.1 2.1 0.2 0.9 0.1 0.1 0.4 0.3 2.0 0.1 0.0 1.1 0.6 0.9 0.4 1.4 0.2 0.1 0.1 4.1 1.1 1.2 0.6 0.2 1.2 1.5 3.4 0.1 8.5 0.7 0.4 4.6 1.4 5.7 6.3 0.2 0.3 6.2 1.6 0.2 0.1 0.0 0.5 0.1 0.3 0.2 0.5 0.3 0.1 0.1 0.9 0.5 0.2 0.2 0.4 0.2 0.5 0.0 0.6 2.4 7.6 6.9 4.9 0.0 0.8 0.0 0.8 0.0 0.0 3.9 5.9 0.0 14.9 15.7 3.1 4.0 6.4 1.9 0.0 40.8 4.5 2.5 2.8 2.8 2.9 0.0 54.2 4.9 6.4 1.7 0.0 1.8 59.1 8.0 25.8 9.1 1.2 1.7 21.2 0.0 7.1 9.7 2.0 10.4 26.0 6.2 3.6 2.0 4.2 33.7 19.8 2.4 2.0 6.8 7.7 6.5 7.2 6.3 5.4 1.0 3.6 7.1 6.2 17.1 4.0 1.7 3.8 9.1 1.7 8.6 1.2 1.1 3.9 49.4 6.6 11.7 10.2 165.9 36.1 0.2 3.7 1.9 6.9 22.2 2.1 4.6 CCDC169-SOHLH2 C13orf38-SOHLH2 ENSG00000250709 "CCDC169-SOHLH2 readthrough" 13 36168794-36297842 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 22 "testis: 10.2" "Cell type enhanced" "Detected in some" "Astrocytes: 1.0;Inhibitory neurons: 1.2;Late spermatids: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.3;HL-60: 2.6;NB-4: 1.5;U-937: 2.0" HPA029182 Uncertain Vesicles NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 32: U-937 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA029182: AB_10602409" "unprognostic (5.56e-2)" "unprognostic (3.93e-1)" "unprognostic (3.60e-2)" "unprognostic (4.66e-1)" "unprognostic (2.17e-1)" "unprognostic (1.84e-2)" "unprognostic (6.12e-2)" "unprognostic (3.43e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 10.2 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.1 2.6 0.0 0.0 0.0 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.9 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.8 0.0 0.4 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCDC190 "C1orf110, MGC48998" ENSG00000185860 "Coiled-coil domain containing 190" Q86UF4 1 162824458-162868815 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "brain: 2.3;choroid plexus: 1.0;esophagus: 3.3;lung: 1.8" "Cell type enriched" "Detected in some" 4 "Respiratory ciliated cells: 26.2" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 3.9;hTERT-RPE1: 4.8;HUVEC TERT2: 4.8;LHCN-M2: 7.3;TIME: 16.7;U-2197: 8.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028579, HPA028584, HPA028592" Uncertain Approved Vesicles NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA028579: AB_10610978, HPA028584: AB_10599423, HPA028592: AB_10601001" "unprognostic (4.29e-1)" "unprognostic (8.37e-2)" "unprognostic (1.75e-1)" "unprognostic (5.47e-2)" "unprognostic (1.68e-2)" "unprognostic (8.33e-3)" "unprognostic (3.04e-2)" "unprognostic (3.09e-2)" "unprognostic (6.41e-2)" "unprognostic (7.41e-5)" "unprognostic (2.64e-1)" "unprognostic (1.52e-1)" "unprognostic (5.26e-1)" "unprognostic (1.70e-1)" 0.1 0.1 0.9 0.0 1.0 0.0 0.0 0.3 1.0 0.1 1.0 0.0 0.0 0.1 0.3 3.3 0.5 0.4 0.5 1.4 2.1 0.0 0.0 1.8 0.0 1.6 2.1 0.0 0.0 0.0 0.1 0.0 1.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.5 0.0 0.1 0.3 2.3 0.0 0.1 0.1 0.4 0.1 0.0 2.3 0.1 0.0 0.0 0.0 0.1 1.7 0.0 0.2 0.2 0.3 0.2 0.0 0.0 0.0 0.3 0.2 0.1 0.1 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 3.9 2.4 4.8 4.8 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.4 0.0 8.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.0 0.3 1.0 1.4 2.1 1.6 2.1 1.0 0.5 2.3 2.3 0.0 0.0 0.5 0.0 0.2 0.0 0.7 0.0 0.6 0.0 0.2 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 2.5 0.6 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 26.2 0.0 0.0 0.4 0.5 0.1 0.2 5.8 0.0 0.0 0.0 0.0 0.0 0.5 CCDC22 "CXorf37, JM1" ENSG00000101997 "Coiled-coil domain containing 22" O60826 X 49235470-49250520 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport, Ubl conjugation pathway" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000229, HPA000888, HPA075980" Uncertain Approved Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 4: Macrophages - Innate immune response" "Endoplasmic reticulum, Vesicles" "HPA000229: , HPA000888: AB_1078420, HPA075980: " "unprognostic (1.24e-2)" "unprognostic (1.96e-2)" "unprognostic (1.98e-2)" "unprognostic (3.45e-1)" "unprognostic (1.36e-1)" "unprognostic (2.80e-2)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.68e-2)" "unprognostic (2.62e-2)" "unprognostic (1.70e-1)" "unprognostic (4.57e-3)" "unprognostic (3.61e-2)" "unprognostic (4.99e-2)" "unprognostic (6.99e-2)" "unprognostic (2.57e-1)" "unprognostic (2.10e-2)" "unprognostic (1.40e-3)" 10.3 12.3 9.4 10.1 10.0 18.6 10.3 9.9 10.8 11.7 8.8 12.1 10.4 12.2 5.3 14.2 11.3 6.4 12.8 9.4 9.2 12.3 12.9 10.7 15.0 10.8 9.4 11.2 14.2 8.7 11.2 6.9 10.1 13.5 5.2 4.7 12.3 8.7 17.2 13.8 13.4 6.0 9.6 20.5 12.9 3.8 10.0 13.6 11.0 7.7 8.5 11.9 11.1 10.8 18.8 16.0 9.6 33.5 8.8 8.9 20.4 10.9 7.9 12.0 13.6 16.3 16.0 6.9 15.9 9.7 14.3 15.0 10.6 18.0 4.9 18.1 23.6 7.3 15.6 15.5 14.7 20.8 12.4 8.2 15.2 15.9 8.6 6.1 11.9 13.7 14.7 11.8 8.6 58.3 15.3 24.4 11.2 9.5 23.2 22.0 15.6 30.1 9.4 9.4 11.4 8.8 16.7 19.4 15.0 9.8 30.2 20.2 13.3 15.4 16.5 19.2 11.6 21.2 12.6 12.5 16.8 38.5 12.3 8.6 37.0 23.8 18.3 30.9 20.1 18.9 18.8 21.3 38.2 16.8 16.7 19.6 2.8 10.8 27.1 15.1 21.8 28.0 9.4 10.0 9.9 10.8 9.4 9.2 10.8 9.4 10.1 9.6 10.0 10.8 8.6 0.0 4.4 3.3 15.0 5.6 9.6 13.0 6.2 11.6 7.4 6.1 2.4 15.7 12.0 11.0 6.2 15.2 11.2 12.5 15.6 13.9 0.3 5.8 4.6 7.8 6.7 8.6 3.7 7.3 14.8 7.6 7.1 6.9 11.4 8.6 11.0 7.2 32.0 1.7 2.9 18.2 8.2 14.4 11.9 0.4 8.1 13.8 7.2 1.9 18.0 9.9 9.2 1.0 4.2 8.6 7.6 7.5 10.2 6.2 15.6 12.1 5.6 8.0 6.6 9.1 9.5 0.1 0.9 8.0 6.7 20.2 13.3 11.0 15.7 8.3 CCDC32 "C15orf57, MGC20481" ENSG00000128891 "Coiled-coil domain containing 32" Q9BV29 15 40528683-40565057 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 80.5;Hofbauer cells: 72.0;Syncytiotrophoblasts: 81.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041688 Uncertain Approved "Nuclear speckles,Vesicles" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles" Vesicles "HPA041688: AB_10796779" "unprognostic (7.10e-2)" "unprognostic (1.04e-1)" "unprognostic (9.86e-3)" "unprognostic (2.30e-2)" "unprognostic (2.65e-1)" "unprognostic (4.25e-5)" "unprognostic (4.03e-2)" "unprognostic (3.39e-2)" "unprognostic (1.15e-1)" "unprognostic (4.70e-2)" "unprognostic (2.34e-1)" "unprognostic (1.23e-2)" "unprognostic (5.77e-2)" "unprognostic (3.72e-1)" "unprognostic (1.18e-1)" "unprognostic (2.20e-1)" "unprognostic (6.47e-2)" 16.0 20.5 16.2 17.0 14.8 20.2 15.5 13.9 18.1 16.0 16.9 17.3 17.0 14.6 17.3 9.3 18.2 17.8 18.1 18.3 17.1 22.8 13.0 14.2 28.7 16.1 17.6 25.0 17.9 20.0 13.6 21.3 18.6 13.9 19.8 15.1 13.0 14.9 15.5 10.3 14.9 15.4 15.6 21.5 18.0 8.3 18.2 19.4 20.9 11.1 25.8 19.2 12.1 16.2 15.4 10.8 14.1 22.8 28.8 29.9 8.4 12.0 17.8 20.9 21.8 16.4 20.9 5.6 32.9 18.0 30.2 28.3 13.8 13.8 14.8 35.0 16.2 62.6 18.1 20.6 19.6 24.0 31.5 25.4 14.1 16.3 11.0 19.8 26.7 22.0 35.0 36.9 16.1 13.3 11.2 20.4 5.6 35.3 13.6 19.1 18.5 19.1 39.6 36.3 15.8 15.5 17.9 18.5 9.3 16.6 19.6 43.4 29.8 19.5 17.0 34.1 17.5 21.1 21.1 18.4 20.7 37.2 27.8 58.2 32.4 33.9 32.6 34.2 25.9 147.1 35.6 35.3 43.0 167.2 35.8 30.7 34.0 29.1 35.7 57.6 50.6 42.1 16.2 14.8 13.9 18.1 18.3 17.1 16.1 17.6 18.6 15.6 18.2 16.2 32.1 12.8 13.4 0.0 24.6 0.0 0.0 0.0 0.0 0.0 18.6 20.8 0.0 0.0 9.9 20.2 0.0 80.5 19.6 0.0 29.4 27.0 0.0 22.7 13.7 10.2 0.0 0.0 0.0 29.2 32.5 11.3 0.0 14.4 6.3 15.5 0.0 0.0 72.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 10.3 0.0 0.0 0.0 0.0 38.3 0.0 0.0 7.8 0.0 0.0 30.0 12.4 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 81.4 10.1 35.0 0.0 0.0 CCDC63 "FLJ35843, ODA5" ENSG00000173093 "Coiled-coil domain containing 63" Q8NA47 12 110846769-110907535 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 17.3" "Group enriched" "Detected in some" 32 "Early spermatids: 305.6;Late spermatids: 241.7" "Cancer enriched" "Detected in single" 12 "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "MCF7: 4.4" HPA061568 Approved "Nucleoplasm,Nuclear bodies,Vesicles" No NA "Cluster 83: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Nuclear bodies" Vesicles "HPA061568: AB_2684561" "unprognostic (1.98e-2)" "unprognostic (1.05e-1)" "unprognostic (1.17e-1)" "unprognostic (2.65e-1)" "unprognostic (5.59e-2)" "unprognostic (1.09e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 17.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 305.6 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 241.7 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.4 4.3 0.0 0.0 0.1 0.0 0.9 0.0 0.0 CCDC65 "CFAP250, CILD27, DRC2, FAP250, FLJ35732, NYD-SP28" ENSG00000139537 "Coiled-coil domain containing 65" Q8IXS2 12 48904110-48931840 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "fallopian tube: 26.6;testis: 37.3" "Cell type enhanced" "Detected in many" "Early spermatids: 151.1;Endometrial ciliated cells: 92.7;Respiratory ciliated cells: 155.7;Spermatocytes: 85.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "gdT-cell: 8.7;MAIT T-cell: 9.1;memory CD4 T-cell: 7.5;memory CD8 T-cell: 7.3;naive CD4 T-cell: 4.6;naive CD8 T-cell: 6.2;T-reg: 4.8" "Lineage enriched" "Detected in single" 11 "T-cells: 9.1" "Cell line enhanced" "Detected in many" "HeLa: 4.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038520, HPA057573" Uncertain Approved "Vesicles,Centriolar satellite" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "Centriolar satellite" "HPA038520: AB_10672714, HPA057573: AB_2683473" "unprognostic (3.06e-2)" "unprognostic (1.17e-1)" "unprognostic (4.22e-2)" "unprognostic (4.20e-3)" "unprognostic (1.44e-2)" "unprognostic (3.43e-2)" "unprognostic (2.86e-2)" "unprognostic (5.79e-3)" "unprognostic (3.23e-1)" "unprognostic (9.02e-2)" "unprognostic (1.52e-2)" "unprognostic (6.03e-4)" "unprognostic (1.69e-3)" "unprognostic (2.04e-1)" "unprognostic (7.80e-2)" "unprognostic (1.34e-2)" "unprognostic (6.16e-2)" 0.4 0.4 1.5 0.7 2.3 1.4 0.4 0.0 2.8 1.4 3.4 0.4 0.3 1.1 2.8 0.3 26.6 1.2 0.3 3.2 0.3 1.8 0.3 2.9 1.0 1.4 2.3 0.8 0.8 1.4 2.1 0.1 1.3 0.4 0.0 7.1 0.3 0.4 0.4 1.5 0.5 0.1 0.5 1.1 0.4 37.3 1.5 0.2 2.5 0.0 0.3 0.2 0.3 0.3 0.6 2.5 1.1 2.2 0.0 0.0 1.1 0.6 0.0 0.3 1.0 3.1 1.4 0.9 0.8 0.0 0.3 0.7 0.0 0.0 0.4 1.4 1.1 1.4 4.4 1.1 0.1 1.1 1.2 0.0 0.0 0.6 0.0 1.7 0.0 0.7 0.6 0.3 0.0 1.5 0.3 1.5 2.5 0.9 0.6 0.8 0.5 1.0 2.0 1.6 0.6 1.0 0.7 0.9 0.8 1.7 2.3 1.0 1.0 0.8 0.8 0.9 0.5 1.1 1.2 0.8 0.9 0.9 0.2 0.0 0.0 0.0 8.7 0.0 9.1 0.2 7.5 7.3 0.0 0.5 4.6 6.2 0.1 0.8 0.0 0.0 4.8 2.9 1.5 2.3 0.0 2.8 3.2 0.3 1.4 2.3 1.3 0.5 1.5 0.3 0.9 0.0 1.1 2.0 0.6 0.9 0.2 6.2 0.0 1.2 0.4 0.5 0.5 0.0 13.8 0.0 12.5 0.1 6.5 0.0 7.9 1.0 151.1 92.7 3.0 0.6 0.0 2.7 7.2 0.6 0.1 0.8 0.5 4.2 0.0 0.5 0.0 0.5 0.0 0.0 4.0 0.0 12.2 0.0 0.8 22.7 1.5 0.3 1.8 1.0 0.2 2.2 33.0 2.0 0.8 0.3 0.0 2.2 1.0 0.2 0.0 3.4 155.7 11.5 0.0 0.5 3.6 85.9 4.8 0.0 0.1 0.1 7.3 0.5 0.0 0.1 CCDC74A FLJ40345 ENSG00000163040 "Coiled-coil domain containing 74A" Q96AQ1 2 131527675-131533666 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 73.5" "Cell type enhanced" "Detected in many" "Early spermatids: 424.4;Late spermatids: 274.9;Respiratory ciliated cells: 166.1;Spermatocytes: 154.2;Theca cells: 211.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 28.6;SCLC-21H: 23.2" HPA060727 Uncertain Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA060727: " "prognostic favorable (5.11e-4)" "unprognostic (2.89e-3)" "unprognostic (6.49e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (2.33e-4)" "unprognostic (1.91e-1)" "unprognostic (1.36e-2)" "unprognostic (2.18e-3)" "unprognostic (1.71e-1)" "unprognostic (2.40e-2)" "unprognostic (1.52e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (1.70e-7)" "unprognostic (7.28e-3)" "prognostic favorable (4.92e-4)" "unprognostic (5.96e-2)" "unprognostic (3.53e-2)" 3.3 32.7 10.6 1.2 9.6 0.1 9.6 7.3 11.3 17.6 29.3 6.9 1.1 12.8 8.9 3.0 34.5 7.0 3.5 11.1 12.2 8.9 1.2 6.2 1.3 12.1 12.8 14.8 2.6 20.4 34.7 1.1 10.5 15.8 1.7 2.0 3.1 6.3 0.5 4.9 2.5 3.0 10.5 1.2 3.2 73.5 15.1 5.3 7.3 0.8 0.8 14.5 8.0 8.0 0.0 5.9 6.0 0.3 8.4 20.2 0.5 5.1 8.4 4.6 3.4 0.2 8.9 2.3 3.1 7.9 7.7 4.6 2.6 1.5 1.9 6.1 11.1 0.0 6.2 0.2 1.0 0.2 0.5 6.6 0.6 4.5 0.0 9.0 1.8 12.7 3.4 6.5 4.2 3.8 13.3 3.6 28.6 2.3 3.8 6.4 0.0 2.7 11.8 0.1 23.2 16.9 0.6 0.8 0.9 2.3 8.2 1.3 1.9 1.4 4.3 18.0 3.9 1.3 1.2 0.8 19.0 0.6 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 9.6 7.3 11.3 11.1 12.2 12.1 12.8 10.5 10.5 15.1 8.0 0.8 0.0 0.5 1.6 0.3 5.1 12.2 21.6 14.2 1.0 34.8 28.4 0.5 4.3 15.8 7.3 0.0 0.5 1.1 0.8 7.9 9.4 424.4 88.2 7.6 1.4 7.7 0.0 3.7 0.7 0.4 11.1 1.1 4.7 0.0 30.4 1.4 0.1 0.3 0.0 2.4 0.6 16.2 0.0 5.9 274.9 37.0 0.8 1.8 1.0 0.0 14.2 0.0 1.0 0.5 2.7 0.5 68.4 0.9 7.4 0.1 2.6 166.1 1.1 0.0 2.5 14.2 154.2 18.8 7.2 6.0 0.3 1.2 211.1 2.4 7.2 CCDC74B DKFZp434E2321 ENSG00000152076 "Coiled-coil domain containing 74B" Q96LY2 2 130139287-130145134 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 55.4" "Cell type enhanced" "Detected in many" "Early spermatids: 322.3;Late spermatids: 129.6;Respiratory ciliated cells: 70.3;Spermatocytes: 142.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 10.2;SH-SY5Y: 14.8" HPA060727 Uncertain Vesicles NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA060727: " "prognostic favorable (4.46e-4)" "unprognostic (4.75e-3)" "unprognostic (2.67e-1)" "unprognostic (2.76e-3)" "unprognostic (2.81e-1)" "unprognostic (1.73e-1)" "unprognostic (8.69e-3)" "unprognostic (9.43e-2)" "unprognostic (2.99e-1)" "unprognostic (2.10e-1)" "unprognostic (6.43e-3)" "unprognostic (7.74e-2)" "prognostic unfavorable (1.55e-4)" "unprognostic (2.43e-2)" "unprognostic (1.48e-4)" "unprognostic (8.31e-3)" "unprognostic (9.94e-3)" 1.5 1.9 3.5 0.3 3.6 0.0 2.4 2.6 4.3 17.0 7.6 1.6 0.2 8.9 0.8 0.4 14.1 1.4 1.5 4.1 5.4 3.8 0.1 2.8 0.3 6.2 7.2 5.0 0.8 11.1 19.7 0.2 5.1 7.1 0.1 0.6 0.6 2.8 0.2 1.0 0.7 1.2 5.7 0.4 1.5 55.4 6.1 0.6 7.0 0.0 0.2 2.4 3.6 3.9 0.0 1.9 2.8 0.1 2.5 5.4 0.6 2.2 1.1 0.3 0.5 0.9 0.7 0.1 3.5 2.0 3.2 1.0 0.2 0.3 0.4 2.0 5.5 0.0 7.0 0.1 0.3 0.1 0.2 1.1 0.0 0.9 0.0 3.4 0.1 1.3 0.1 1.7 0.8 2.1 0.0 0.0 5.7 0.5 5.9 4.6 0.0 3.2 1.7 0.0 10.2 14.8 1.6 0.1 0.2 0.6 5.9 0.7 0.4 1.1 4.8 5.9 0.5 0.1 0.3 0.0 6.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 3.6 2.6 4.3 4.1 5.4 6.2 7.2 5.1 5.7 6.1 3.9 0.2 3.2 0.5 1.6 0.1 0.5 3.0 6.3 1.2 0.5 6.1 9.5 0.4 1.5 4.3 5.5 0.0 0.2 0.2 0.1 3.9 1.5 322.3 42.8 9.9 0.2 11.4 0.0 1.6 0.2 0.8 3.6 0.0 2.2 0.0 7.8 0.0 0.0 0.3 3.3 1.1 0.1 2.0 0.0 0.2 129.6 10.2 0.6 0.0 1.0 0.0 6.2 0.0 0.5 0.3 0.0 0.1 12.4 0.1 3.9 0.0 1.2 70.3 0.1 0.0 0.9 3.2 142.7 16.4 0.7 1.1 0.1 0.3 28.8 0.1 0.7 CCDC93 FLJ10996 ENSG00000125633 "Coiled-coil domain containing 93" Q567U6 2 117915478-118014133 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054183 Approved Enhanced "Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" Vesicles "Plasma membrane" "HPA054183: AB_2682408" "unprognostic (1.47e-1)" "unprognostic (6.55e-2)" "unprognostic (8.29e-2)" "unprognostic (1.02e-2)" "unprognostic (3.32e-2)" "unprognostic (2.47e-3)" "prognostic unfavorable (2.97e-6)" "unprognostic (2.51e-1)" "unprognostic (8.12e-2)" "unprognostic (8.99e-2)" "unprognostic (1.52e-3)" "unprognostic (8.56e-2)" "unprognostic (4.87e-1)" "unprognostic (1.79e-2)" "unprognostic (2.67e-1)" "prognostic unfavorable (9.66e-4)" "unprognostic (2.40e-2)" 10.2 14.5 9.3 10.4 8.5 21.7 9.6 9.6 12.7 9.1 15.0 11.3 11.9 8.2 9.8 7.4 9.3 7.1 21.3 8.4 9.4 9.8 7.8 11.8 10.3 9.7 9.0 13.3 13.0 15.9 16.1 8.1 10.3 7.6 10.6 26.0 9.1 8.4 12.9 11.0 12.8 8.1 8.4 12.1 9.1 12.1 11.5 10.1 11.9 10.3 10.1 8.6 8.1 8.5 18.7 8.1 22.0 19.4 31.2 21.3 18.5 21.8 14.2 14.0 14.3 17.7 11.7 15.9 14.5 17.1 24.9 15.8 12.8 11.2 18.1 20.8 13.0 20.1 15.5 23.9 13.7 22.1 22.0 14.6 11.5 21.9 25.9 19.4 15.0 18.9 11.1 11.0 15.8 8.1 14.0 23.8 9.9 13.4 13.0 17.6 17.2 10.7 11.5 19.6 17.4 10.3 14.2 10.6 15.1 19.6 8.9 13.5 21.2 23.9 20.0 20.4 15.3 14.3 16.0 24.7 13.8 16.1 14.2 2.9 1.6 1.8 2.1 2.1 2.0 1.6 1.5 1.8 1.2 1.4 2.0 1.7 1.7 1.7 1.3 0.5 0.7 1.0 9.3 8.5 9.6 12.7 8.4 9.4 9.7 9.0 10.3 8.4 11.5 8.5 17.4 19.2 28.2 61.0 28.6 17.6 14.6 11.2 9.6 32.0 12.4 10.0 43.0 7.2 17.5 1.8 47.9 12.6 31.9 21.5 9.8 24.0 4.5 14.9 15.2 16.5 16.7 9.9 57.1 16.7 8.5 14.7 11.7 17.0 15.2 25.1 12.8 6.0 15.2 20.2 60.6 11.4 10.2 16.3 15.9 10.6 13.7 19.9 3.6 32.8 19.9 13.8 20.6 53.3 37.9 32.0 11.9 14.3 19.4 13.9 17.1 9.4 16.3 36.0 6.6 21.4 15.0 46.0 31.1 10.1 16.1 12.9 24.3 12.8 14.0 15.0 CCL15 "HCC-2, HMRP-2B, Lkn-1, MIP-1d, MIP-5, NCC-3, SCYA15, SCYL3" ENSG00000275718 "C-C motif chemokine ligand 15" Q16663 17 35996440-36001553 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Cytokine, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 83.0;liver: 31.6" "Cell type enhanced" "Detected in some" "Distal enterocytes: 262.6;Intestinal goblet cells: 208.3;Paneth cells: 380.6;Proximal enterocytes: 461.4;Undifferentiated cells: 138.2" "Cancer enhanced" "Detected in many" "liver cancer: 11.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "Hep G2: 35.4;OE19: 28.7" HPA058608 Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 3270000 11000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus" Vesicles "HPA058608: AB_2683776" "unprognostic (1.26e-1)" "unprognostic (1.23e-1)" "unprognostic (1.31e-2)" "unprognostic (1.40e-1)" "unprognostic (8.88e-2)" "unprognostic (1.50e-1)" "unprognostic (1.63e-1)" "unprognostic (2.45e-1)" "unprognostic (2.41e-2)" "unprognostic (1.96e-2)" "unprognostic (9.94e-2)" "unprognostic (1.15e-1)" "unprognostic (1.07e-2)" "prognostic favorable (3.02e-4)" 0.2 0.4 0.1 7.8 0.1 0.1 0.4 0.1 0.3 0.3 0.0 59.7 37.6 0.1 0.0 0.2 9.6 9.2 0.0 0.1 0.1 10.0 31.6 2.1 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 83.0 0.0 0.1 0.1 0.0 0.1 62.0 1.4 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.3 4.9 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 35.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.1 0.0 28.7 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.3 0.5 0.0 0.5 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.1 0.1 7.2 5.0 0.0 0.0 0.0 0.0 262.6 0.0 0.0 0.0 12.2 0.1 0.7 71.8 0.0 0.0 0.7 0.0 0.0 0.0 0.1 8.9 0.0 2.5 40.2 0.1 0.0 0.0 208.3 2.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 380.6 0.0 0.0 0.0 461.4 61.3 76.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 138.2 0.2 CCL2 "GDCF-2, HC11, MCAF, MCP-1, MCP1, MGC9434, SCYA2, SMC-CF" ENSG00000108691 "C-C motif chemokine ligand 2" P13500 17 34255218-34257203 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 756.1" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 1152.5;Ductal cells: 3382.2;Exocrine glandular cells: 919.2;Prostatic glandular cells: 889.0;Skeletal myocytes: 994.7;Smooth muscle cells: 1507.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 7.5;eosinophil: 3.0" "Group enriched" "Detected in many" 6 "granulocytes: 3.0;monocytes: 7.5" "Group enriched" "Detected in many" 4 "BJ hTERT+: 1902.2;HMC-1: 2427.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "midbrain: 9.9;spinal cord: 39.4" "CAB013676, HPA019163" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 323000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" Vesicles "CAB013676: , HPA019163: AB_1846179" "unprognostic (6.43e-2)" "unprognostic (4.14e-2)" "unprognostic (4.78e-2)" "unprognostic (5.57e-2)" "unprognostic (2.37e-3)" "unprognostic (8.64e-2)" "unprognostic (2.78e-2)" "unprognostic (7.53e-2)" "unprognostic (2.90e-1)" "unprognostic (1.19e-1)" "unprognostic (9.33e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (4.51e-4)" "unprognostic (1.33e-1)" "unprognostic (2.50e-2)" "unprognostic (1.81e-1)" "unprognostic (4.92e-2)" 390.9 129.8 15.6 167.2 15.1 96.5 76.8 14.7 26.8 20.4 24.4 169.5 41.2 30.2 15.0 47.1 85.6 256.5 305.8 16.0 21.1 229.5 161.1 405.1 78.4 32.7 16.5 19.3 141.6 34.6 70.5 39.1 21.9 153.1 103.5 11.5 47.0 45.4 19.6 40.3 80.3 150.7 21.4 73.2 121.2 12.1 43.3 142.7 84.4 47.0 16.6 756.1 36.3 25.3 0.1 15.3 40.4 0.0 110.7 94.5 0.3 116.6 1902.2 243.3 516.8 7.1 0.2 0.3 90.4 27.6 3.8 64.0 4.3 0.1 122.9 0.6 0.9 0.2 13.5 0.0 3.5 0.4 2427.9 105.9 0.0 50.6 2.9 162.6 112.4 0.0 6.5 20.2 0.0 0.0 0.7 19.6 5.8 0.0 0.4 0.6 3.3 20.9 354.7 0.0 0.1 8.1 0.3 6.0 3.3 108.4 4.6 2.5 6.4 129.0 5.7 3.6 0.7 1.2 0.5 0.1 75.7 37.6 84.3 0.0 7.5 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 1.6 15.6 15.1 14.7 26.8 16.0 21.1 32.7 16.5 21.9 21.4 43.3 25.3 218.3 182.7 126.5 2.0 3.6 568.6 866.2 595.3 1152.5 0.1 23.5 50.9 29.5 92.9 120.7 138.0 0.0 2.7 2.2 0.0 0.0 3382.2 0.0 8.4 37.8 577.2 0.0 0.0 0.7 919.2 3.6 840.5 5.6 11.4 353.0 0.1 50.3 0.4 439.1 0.0 0.1 0.0 6.1 8.9 408.5 0.4 12.2 593.1 213.5 8.4 37.8 13.8 0.0 0.0 0.1 781.2 0.0 1.5 2.9 889.0 0.0 67.7 27.7 0.7 131.5 994.7 1507.0 0.4 0.3 13.0 222.8 4.5 44.3 1.7 0.1 40.6 CCN2 "CTGF, IGFBP8" ENSG00000118523 "Cellular communication network factor 2" P29279 6 131948176-131951372 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cell adhesion, DNA synthesis" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 101.2;Cardiomyocytes: 38.7;Extravillous trophoblasts: 47.1;Fibroblasts: 261.8;Smooth muscle cells: 104.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive B-cell: 8.1" "Lineage enriched" "Detected in single" 81 "B-cells: 8.1" "Cell line enhanced" "Detected in many" "EFO-21: 1605.0;HUVEC TERT2: 1377.0;TIME: 2874.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005123, HPA031074, HPA031075" Approved Approved "Golgi apparatus,Vesicles" "Secreted in other tissues" No No 1010000 5900000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "CAB005123: AB_638805, HPA031074: AB_10599618, HPA031075: AB_10611248" "unprognostic (2.87e-1)" "unprognostic (1.43e-1)" "unprognostic (4.41e-2)" "unprognostic (5.68e-2)" "unprognostic (9.79e-2)" "unprognostic (1.82e-2)" "unprognostic (3.38e-1)" "unprognostic (4.96e-2)" "unprognostic (1.68e-1)" "unprognostic (3.89e-2)" "unprognostic (2.39e-1)" "unprognostic (2.06e-1)" "unprognostic (1.27e-3)" "prognostic unfavorable (5.04e-4)" "unprognostic (1.62e-1)" "unprognostic (1.77e-2)" "unprognostic (3.84e-3)" 265.9 107.5 18.9 168.0 18.8 2.0 206.4 16.3 34.0 531.0 31.5 148.8 43.7 418.5 34.4 271.9 243.8 441.4 371.8 25.8 14.2 235.7 82.9 226.3 73.6 18.8 32.1 77.0 194.0 43.0 44.8 198.2 20.2 364.6 136.1 2.4 138.2 154.3 51.8 155.1 151.2 576.3 14.2 569.1 182.6 24.7 20.8 49.5 464.7 61.9 14.9 324.0 102.5 18.2 4.6 7.5 126.8 3.7 279.9 158.5 1.8 373.1 178.2 226.8 119.4 0.2 12.2 0.6 1605.0 482.7 185.0 6.2 4.2 26.4 211.3 2.5 3.5 0.2 55.7 137.3 109.6 0.3 0.5 232.2 5.9 163.9 40.2 340.7 1377.0 0.0 0.4 0.3 650.8 2.5 0.5 1.2 61.8 41.3 21.7 32.6 6.0 0.7 81.9 0.4 0.5 0.8 38.3 62.2 18.3 308.5 6.1 3.1 2874.4 311.6 242.4 397.8 694.0 11.5 1.7 4.1 42.5 0.7 399.2 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 18.9 18.8 16.3 34.0 25.8 14.2 18.8 32.1 20.2 14.2 20.8 18.2 101.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.7 0.0 0.0 0.0 0.0 17.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 0.0 0.0 47.1 261.8 0.0 0.0 0.0 0.0 0.0 0.0 13.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 104.4 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 CCN3 "IGFBP9, NOV" ENSG00000136999 "Cellular communication network factor 3" P48745 8 119416446-119424434 "Plasma proteins, Predicted secreted proteins, Transporters" "Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 44 "adrenal gland: 1105.4" "Cell type enhanced" "Detected in some" "Adipocytes: 25.2;Endothelial cells: 2.7;Fibroblasts: 9.8;Smooth muscle cells: 4.6" "Cancer enriched" "Detected in all" 4 "melanoma: 62.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 116 "eosinophil: 64.8;neutrophil: 30.8" "Lineage enriched" "Detected in single" 157 "granulocytes: 64.8" "Cell line enhanced" "Detected in many" "BJ hTERT+: 125.0;hTERT-RPE1: 38.1;U-2197: 128.2" "Group enriched" "Detected in all" 6 "amygdala: 129.2;basal ganglia: 51.5;cerebral cortex: 99.5;hippocampal formation: 152.5;white matter: 85.0" "Region enriched" "Detected in all" 6 "spinal cord: 114.6" "HPA018449, HPA019684, CAB034423" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 269000000 2800000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB034423: AB_2151387, HPA018449: AB_1846189, HPA019684: AB_1846190" "unprognostic (5.04e-2)" "unprognostic (1.01e-1)" "unprognostic (7.36e-3)" "unprognostic (1.30e-3)" "unprognostic (9.35e-3)" "unprognostic (4.92e-1)" "unprognostic (8.10e-2)" "unprognostic (6.04e-2)" "unprognostic (1.79e-2)" "unprognostic (9.17e-2)" "unprognostic (1.67e-1)" "unprognostic (3.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.74e-3)" "unprognostic (1.51e-1)" "unprognostic (1.98e-1)" "unprognostic (2.72e-2)" 23.7 1105.4 7.6 3.6 11.5 1.7 8.1 6.7 12.2 11.2 5.9 6.9 3.9 8.6 6.3 5.5 9.0 6.3 18.1 16.2 9.7 6.9 1.1 6.8 2.2 5.6 6.5 3.1 6.8 9.4 21.8 0.6 4.9 22.8 7.0 1.2 2.7 20.0 4.7 13.8 4.4 8.4 8.7 1.5 4.9 3.6 6.3 1.0 25.3 7.2 1.9 4.4 8.0 6.2 0.1 3.1 1.7 0.0 11.1 2.9 0.1 16.9 125.0 14.9 8.6 0.0 0.3 0.0 12.9 21.2 11.6 10.5 0.6 0.0 5.1 0.0 0.3 0.0 9.1 0.0 0.4 0.0 0.0 0.6 0.1 5.7 0.6 38.1 0.4 0.0 0.0 0.0 0.8 0.7 0.0 0.1 0.2 1.2 24.9 0.1 0.0 0.0 15.8 0.1 3.9 0.1 6.3 0.1 24.2 0.0 0.0 0.0 0.0 10.6 15.8 128.2 3.5 0.0 0.0 0.0 16.7 5.4 12.5 0.0 0.3 64.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 30.8 0.0 0.0 0.0 0.0 0.1 7.6 11.5 6.7 12.2 16.2 9.7 5.6 6.5 4.9 8.7 6.3 6.2 25.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 CCZ1 "C7orf28A, CCZ1A, CGI-43" ENSG00000122674 "CCZ1 homolog, vacuolar protein trafficking and biogenesis associated" P86791 7 5898725-5926550 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045114, HPA050006" Uncertain Enhanced Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Vesicles "HPA045114: AB_2679219, HPA050006: AB_2680989" "unprognostic (1.91e-1)" "unprognostic (2.97e-3)" "unprognostic (3.15e-2)" "unprognostic (1.25e-2)" "unprognostic (1.82e-1)" "unprognostic (5.35e-2)" "unprognostic (3.74e-3)" "unprognostic (4.10e-1)" "unprognostic (9.25e-3)" "unprognostic (7.66e-2)" "unprognostic (6.64e-2)" "unprognostic (2.67e-2)" "unprognostic (5.27e-3)" "unprognostic (3.25e-1)" "unprognostic (1.31e-1)" "unprognostic (1.74e-1)" "unprognostic (4.41e-1)" 32.5 55.8 10.7 12.8 10.9 26.9 30.2 12.2 13.7 28.7 12.9 31.1 13.0 29.7 9.4 40.8 25.2 10.3 31.3 11.4 10.5 27.3 27.3 26.0 15.4 10.7 10.4 23.0 27.3 29.9 24.9 12.2 10.6 24.6 16.0 12.6 32.1 11.9 43.2 30.3 26.9 13.9 10.5 31.5 29.0 22.1 11.0 20.5 25.5 13.0 16.2 31.7 28.9 11.6 52.2 29.8 30.3 27.1 41.8 35.4 15.3 15.6 30.1 23.1 25.0 9.1 27.2 42.8 4.8 40.8 61.9 27.8 16.6 26.7 26.5 16.2 37.3 18.1 30.2 16.8 38.0 13.1 7.1 40.5 42.4 15.6 19.5 42.5 57.2 25.4 52.4 29.7 38.8 26.9 16.8 56.9 39.5 26.4 28.3 36.0 13.8 28.9 21.1 38.3 23.9 31.9 15.3 36.6 13.6 57.9 26.1 21.0 27.7 28.8 57.4 18.7 25.7 13.6 24.6 58.0 9.6 30.8 41.6 3.1 1.9 2.7 1.8 2.3 1.4 1.3 2.2 2.2 1.8 1.3 1.5 1.6 3.4 3.0 2.4 1.8 4.6 0.7 10.7 10.9 12.2 13.7 11.4 10.5 10.7 10.4 10.6 10.5 11.0 11.6 30.7 3.2 23.5 15.7 26.3 45.2 30.6 21.2 9.6 59.2 29.5 20.2 11.0 24.3 24.0 31.3 62.6 45.0 47.2 38.0 31.3 61.0 6.5 18.7 18.1 35.0 29.9 26.7 20.2 71.4 35.9 26.7 11.2 21.3 15.8 21.1 76.4 17.6 35.7 23.5 20.5 30.8 50.8 39.0 61.6 4.9 37.9 27.5 46.2 8.4 80.8 41.5 72.1 15.6 28.7 74.0 30.1 36.1 14.3 26.2 40.2 21.9 32.9 69.2 78.9 19.4 32.0 40.6 34.5 11.0 54.1 34.9 32.8 38.2 34.4 33.7 CCZ1B "C7orf28B, DKFZP586I1023, H_NH0577018.2, MGC19819" ENSG00000146574 "CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated" P86790 7 6794134-6826770 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA045114, HPA050006" Uncertain Enhanced Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 32: U-937 - Innate immune response" "Cluster 59: Non-specific - Transcription" Vesicles "HPA045114: AB_2679219, HPA050006: AB_2680989" "unprognostic (8.06e-3)" "unprognostic (1.53e-1)" "unprognostic (2.94e-2)" "unprognostic (1.00e-1)" "unprognostic (4.94e-2)" "unprognostic (1.45e-2)" "unprognostic (1.88e-3)" "unprognostic (2.74e-1)" "unprognostic (9.14e-2)" "unprognostic (1.06e-1)" "unprognostic (2.15e-1)" "unprognostic (2.86e-1)" "unprognostic (2.96e-3)" "unprognostic (9.61e-2)" "unprognostic (1.27e-1)" "unprognostic (2.73e-2)" "unprognostic (1.24e-1)" 28.9 40.3 19.6 25.1 20.0 37.1 28.8 20.6 26.2 18.5 22.4 31.3 27.5 28.5 40.3 42.5 25.6 28.4 28.6 19.5 20.3 28.8 24.1 23.5 38.0 19.8 19.6 18.2 21.1 73.1 9.1 26.7 19.8 20.8 27.2 32.4 32.9 19.0 35.8 30.2 22.0 22.5 20.7 25.4 30.8 23.5 20.5 38.8 24.6 53.5 35.5 39.4 9.3 21.6 120.6 31.6 66.8 138.5 49.7 51.5 67.2 64.1 69.4 58.1 61.4 32.4 65.7 52.2 57.0 72.0 132.5 68.7 87.9 60.5 62.4 31.1 51.8 33.6 40.7 72.0 54.3 165.4 104.1 37.9 37.6 51.1 30.2 40.0 57.9 108.6 63.5 49.2 62.6 124.7 84.2 81.5 171.2 78.2 66.7 67.3 123.1 59.4 41.8 66.4 87.1 161.5 62.4 117.6 78.8 65.9 94.0 185.0 71.1 27.7 93.7 78.2 116.5 52.9 104.8 45.6 53.9 176.4 120.9 21.8 5.5 10.2 5.3 8.0 6.3 6.1 6.7 7.8 8.3 5.1 4.5 5.8 4.6 10.6 15.5 6.3 15.7 3.4 19.6 20.0 20.6 26.2 19.5 20.3 19.8 19.6 19.8 20.7 20.5 21.6 9.5 6.4 12.7 11.1 17.4 8.4 7.8 8.6 8.0 10.4 10.9 10.0 7.3 2.8 10.7 3.7 14.6 8.0 12.9 18.7 15.6 20.1 3.7 16.0 11.1 8.9 18.6 9.0 19.6 28.1 11.7 9.2 9.2 10.3 2.5 6.6 15.7 7.1 9.8 16.8 19.0 17.5 6.1 11.1 22.8 2.2 7.2 11.2 14.2 8.4 24.7 11.5 17.5 14.6 23.6 24.8 11.9 10.5 7.6 9.6 7.1 12.4 23.7 11.4 19.7 8.1 9.0 12.0 8.9 11.0 12.5 7.9 11.1 5.7 15.3 11.9 CD14 ENSG00000170458 "CD14 molecule" P08571 5 140631728-140633701 "Cancer-related genes, CD markers, Human disease related genes, Plasma proteins, Predicted secreted proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 403.4" "Cell type enriched" "Detected in many" 4 "Hofbauer cells: 2809.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3697.0" "Group enriched" "Detected in all" 5 "granulocytes: 942.3;monocytes: 3697.0" "Cell line enhanced" "Detected in many" "A549: 10.1;CACO-2: 17.0;SiHa: 21.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001887, HPA002127, CAB033631, CAB072865, CAB072866" Enhanced Approved Vesicles "Secreted to blood" NA NA 2750000000 10000000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB033631: AB_781932, CAB072865: AB_2665714, CAB072866: AB_2665715, HPA001887: AB_1078442, HPA002127: AB_1078440" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (3.42e-3)" "unprognostic (3.89e-2)" "unprognostic (3.29e-2)" "unprognostic (1.54e-1)" "unprognostic (4.71e-3)" "unprognostic (4.88e-2)" "unprognostic (2.16e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.80e-5)" "unprognostic (1.20e-2)" "unprognostic (6.87e-3)" "unprognostic (8.12e-2)" "unprognostic (6.92e-2)" 134.5 151.3 15.9 236.1 16.0 68.8 50.5 14.7 33.1 27.9 26.8 55.9 31.4 23.5 21.0 23.9 40.5 79.8 35.6 14.5 23.2 41.6 403.4 91.6 107.9 33.6 26.4 21.4 27.0 16.7 35.5 183.0 29.6 18.3 47.6 4.0 121.8 30.4 10.6 13.5 38.0 111.7 25.4 87.6 33.9 26.6 30.3 20.9 23.0 17.5 23.0 102.5 12.6 42.1 0.1 10.1 0.1 0.8 1.3 0.3 0.5 0.9 4.7 1.9 2.1 17.0 3.1 0.4 1.0 5.9 1.4 4.9 0.0 2.6 0.5 0.1 1.4 0.3 1.1 2.0 5.1 1.1 0.3 4.8 0.3 0.3 1.5 0.4 0.0 0.3 0.3 0.3 1.7 0.3 0.1 1.2 0.4 0.3 0.3 0.4 0.6 1.8 0.2 0.1 3.6 1.3 21.1 0.5 0.5 0.2 0.3 2.1 0.6 0.4 0.4 1.9 2.1 0.8 1.6 0.8 0.4 0.5 0.1 13.5 3697.0 21.7 6.8 677.3 8.7 12.1 3.7 3.9 440.4 1.9 5.2 3.6 942.3 3.8 95.1 25.2 3.7 3034.0 15.9 16.0 14.7 33.1 14.5 23.2 33.6 26.4 29.6 25.4 30.3 42.1 17.9 9.6 27.6 0.7 9.0 5.1 3.4 5.2 6.2 7.2 164.9 23.4 2.6 22.8 18.3 1.8 0.0 18.1 5.3 77.2 1.9 5.1 2.3 0.6 1.7 46.5 7.2 29.5 0.7 1.8 16.3 19.7 1.1 1.0 8.8 0.6 340.2 348.0 2809.2 33.7 0.9 5.9 4.1 668.4 75.9 6.1 5.0 652.8 8.8 23.4 285.3 30.0 11.3 0.5 0.4 1.8 35.3 5.3 1.8 1.7 5.0 7.0 9.8 5.1 32.9 25.8 9.7 1.5 2.0 4.4 4.3 46.1 5.5 2.1 7.4 4.9 CD1B CD1 ENSG00000158485 "CD1b molecule" P29016 1 158327951-158331531 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 157 "lymphoid tissue: 528.9" "Cell type enriched" "Detected in some" 21 "Langerhans cells: 153.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "myeloid DC: 19.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 19.2" "Cell line enriched" "Detected in some" 5 "MOLT-4: 587.9" HPA021824 Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus, Vesicles" Cytosol "HPA021824: AB_1846262" "unprognostic (7.72e-3)" "unprognostic (1.55e-4)" "unprognostic (1.66e-5)" "unprognostic (1.04e-2)" "unprognostic (1.06e-3)" "unprognostic (1.81e-1)" "unprognostic (2.89e-4)" "unprognostic (2.27e-2)" "unprognostic (2.19e-1)" "unprognostic (1.33e-1)" "unprognostic (9.53e-2)" "unprognostic (3.23e-1)" "unprognostic (3.52e-1)" "unprognostic (1.56e-1)" "unprognostic (1.89e-1)" "unprognostic (3.53e-2)" 0.1 0.0 0.0 1.2 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.0 0.6 0.0 0.7 0.1 0.0 0.0 0.1 0.2 1.0 2.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.0 3.3 0.2 0.1 0.0 1.0 0.7 0.0 0.0 528.9 0.3 0.1 1.4 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 118.6 0.0 0.0 0.0 0.0 587.9 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 2.8 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.9 153.1 0.2 0.0 7.0 1.8 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 CD1C CD1 ENSG00000158481 "CD1c molecule" P29017 1 158289923-158294774 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "lymphoid tissue: 130.4" "Cell type enriched" "Detected in some" 6 "Langerhans cells: 551.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory B-cell: 84.1;myeloid DC: 324.9" "Group enriched" "Detected in many" 8 "B-cells: 84.1;dendritic cells: 324.9" "Group enriched" "Detected in some" 10 "JURKAT: 14.8;MOLT-4: 49.4" HPA068359 Approved "Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA 200000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Golgi apparatus, Vesicles" "Endoplasmic reticulum" "HPA068359: " "unprognostic (2.55e-3)" "prognostic favorable (1.79e-5)" "unprognostic (1.75e-5)" "unprognostic (3.09e-5)" "unprognostic (3.12e-2)" "unprognostic (8.13e-3)" "unprognostic (2.01e-1)" "unprognostic (3.80e-3)" "unprognostic (7.11e-3)" "unprognostic (1.87e-1)" "unprognostic (7.41e-2)" "unprognostic (1.93e-1)" "unprognostic (1.04e-1)" "unprognostic (1.46e-1)" "unprognostic (1.67e-1)" "unprognostic (8.05e-2)" "unprognostic (1.99e-1)" 2.7 0.8 0.0 17.3 0.0 1.1 5.0 0.0 0.2 2.3 0.0 3.4 2.0 2.4 0.6 4.5 1.8 7.7 2.0 0.0 0.0 1.2 4.1 6.5 26.2 0.0 0.0 0.9 0.7 0.6 0.2 0.1 0.0 1.8 9.4 0.0 2.8 1.3 1.0 12.2 12.0 3.1 0.0 23.0 3.7 0.9 0.0 130.4 0.7 1.1 38.2 4.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 49.4 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.9 0.0 0.6 26.8 0.1 0.1 24.7 0.3 84.1 0.1 0.0 324.9 49.1 0.2 0.0 1.1 4.1 3.7 1.5 0.5 15.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 5.2 0.0 26.6 13.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 4.1 0.0 0.1 1.5 0.0 0.8 0.0 0.0 0.1 1.4 0.0 0.0 3.8 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 7.1 551.4 4.5 0.0 91.2 19.6 0.0 11.8 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 1.5 0.0 0.0 0.2 0.4 0.1 0.3 0.0 7.4 0.0 1.9 0.0 0.0 0.0 CD24 CD24A ENSG00000272398 "CD24 molecule" P25063 6 106969831-106975627 "Cancer-related genes, CD markers, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 1630.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1572.7;Distal tubular cells: 1590.6;Exocrine glandular cells: 3454.1;Glandular and luminal cells: 1441.8;Pancreatic endocrine cells: 1694.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 28 "eosinophil: 86.2;memory B-cell: 61.1;naive B-cell: 39.7" "Group enriched" "Detected in many" 237 "B-cells: 61.1;granulocytes: 86.2" "Cell line enhanced" "Detected in many" "NTERA-2: 989.4;RPTEC TERT1: 4702.6;RT4: 931.5;SK-BR-3: 1352.5" "HPA045879, CAB078471" Approved Enhanced Vesicles "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 30: Mammary glandular cells - Lactation" Vesicles "CAB078471: AB_10983158, HPA045879: AB_2732523" "prognostic unfavorable (2.44e-5)" "unprognostic (6.64e-2)" "prognostic favorable (3.29e-4)" "unprognostic (1.87e-1)" "unprognostic (1.41e-2)" "unprognostic (9.98e-2)" "prognostic unfavorable (7.58e-4)" "unprognostic (2.32e-1)" "unprognostic (2.74e-1)" "unprognostic (1.04e-1)" "unprognostic (2.28e-2)" "unprognostic (1.51e-1)" "unprognostic (5.10e-2)" "unprognostic (2.92e-1)" "unprognostic (1.16e-1)" "unprognostic (2.01e-1)" "unprognostic (3.13e-1)" 7.1 61.9 23.3 139.1 28.8 704.5 468.1 6.4 30.0 288.0 36.7 1071.8 89.0 181.5 229.6 1456.5 242.9 874.3 5.1 45.0 29.2 775.6 30.2 61.6 77.8 26.6 26.0 2.2 1383.4 2.5 12.5 151.7 17.2 148.8 740.8 2.6 952.4 546.9 1.4 77.2 69.8 117.7 19.5 29.6 601.7 4.9 38.6 15.2 1630.2 1.1 445.0 168.9 468.3 50.7 363.2 225.2 3.9 28.6 0.7 0.3 405.8 0.4 2.6 2.0 1.2 3.3 1.9 35.4 106.0 0.1 14.6 730.6 124.1 275.6 1.5 1.0 1.7 1.0 254.2 16.3 0.2 5.1 1.8 2.1 316.1 3.6 18.0 16.9 1.6 1.4 8.3 0.8 6.6 465.6 2.4 2.6 989.4 800.1 85.6 846.8 0.5 3.5 4702.6 931.5 612.4 448.7 250.0 1352.5 1.4 437.1 635.6 2.1 1.6 0.8 4.0 3.1 11.8 1.0 2.0 475.2 5.0 2.9 1.6 0.3 0.1 86.2 0.0 0.0 0.0 61.1 0.0 0.0 0.0 39.7 0.0 0.1 2.1 0.1 0.3 0.1 0.0 2.0 23.3 28.8 6.4 30.0 45.0 29.2 26.6 26.0 17.2 19.5 38.6 50.7 10.2 157.0 83.5 0.7 157.5 0.0 70.4 0.0 7.4 5.8 1109.4 325.4 1.5 1112.3 98.4 1302.1 2.1 749.2 13.7 1572.7 1590.6 1274.1 22.5 1237.6 254.2 38.6 575.4 5.3 0.6 3454.1 885.0 29.9 567.2 1441.8 10.8 0.6 97.5 9.7 70.8 0.0 5.7 463.6 0.0 7.6 0.0 53.4 10.2 17.6 0.0 1.0 32.6 1.0 0.0 0.0 0.1 1694.3 865.2 2.2 1.0 810.2 12.3 538.5 376.8 0.7 6.6 2.9 18.1 0.6 7.2 587.7 0.0 558.3 28.1 0.0 932.8 1043.7 CD276 "B7-H3, B7H3, B7RP-2" ENSG00000103855 "CD276 molecule" Q5ZPR3 15 73683966-73714514 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 215.6;Hofbauer cells: 82.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 175.0;U-2197: 231.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009285, HPA017139, CAB017826" Enhanced Approved Vesicles NA NA 16000000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "CAB017826: , HPA009285: AB_1078258, HPA017139: AB_1845246" "unprognostic (1.05e-1)" "unprognostic (4.74e-3)" "unprognostic (4.57e-3)" "unprognostic (9.62e-2)" "unprognostic (1.26e-2)" "unprognostic (5.50e-3)" "prognostic unfavorable (9.81e-4)" "unprognostic (2.57e-3)" "unprognostic (1.89e-1)" "unprognostic (3.75e-2)" "unprognostic (1.54e-2)" "unprognostic (3.29e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (1.17e-1)" "unprognostic (9.22e-2)" "unprognostic (1.21e-1)" "unprognostic (1.34e-3)" 24.1 19.1 6.6 12.9 4.3 0.7 15.3 0.4 6.5 22.2 15.6 11.4 11.0 20.2 4.3 5.8 10.0 18.2 14.8 4.2 5.7 5.4 11.8 11.6 3.6 5.9 6.7 13.4 15.3 4.3 6.1 26.2 4.1 16.7 4.2 4.6 15.0 9.6 5.0 16.2 8.4 10.8 2.4 9.0 10.9 6.0 7.5 1.6 8.5 2.2 1.6 14.6 13.0 6.7 43.7 44.6 32.5 82.8 57.7 35.0 102.8 47.5 42.0 33.4 30.4 85.3 90.1 0.6 77.7 39.5 64.1 175.0 31.7 39.9 4.4 30.6 76.3 2.8 47.6 47.1 20.9 0.7 51.8 32.7 17.9 28.3 15.4 19.7 38.7 0.0 15.0 0.8 6.2 66.0 0.3 2.3 84.9 8.6 35.9 0.5 47.9 7.0 27.9 53.8 24.9 59.5 40.1 21.2 88.0 23.0 38.1 26.4 49.8 68.6 60.0 231.6 52.5 0.9 0.8 0.8 114.8 3.4 49.4 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.1 0.0 0.0 6.6 4.3 0.4 6.5 4.2 5.7 5.9 6.7 4.1 2.4 7.5 6.7 4.4 19.2 8.1 6.5 1.2 15.0 11.5 12.5 8.0 20.2 14.1 11.8 9.1 2.8 17.0 11.0 31.3 11.6 0.2 6.7 1.9 48.6 0.9 14.4 26.7 22.0 9.0 0.0 18.4 19.0 215.6 43.7 14.3 31.6 14.7 41.4 4.6 14.6 82.5 10.1 12.9 13.1 4.1 8.8 30.8 2.2 9.9 14.7 24.9 7.5 4.2 8.4 0.0 5.5 1.7 24.7 15.1 17.3 1.7 12.1 3.1 2.7 5.8 27.5 13.1 7.0 32.1 1.8 4.9 3.4 10.2 12.3 1.4 8.4 10.6 8.4 CD300A "CMRF-35-H9, CMRF35H, IGSF12, IRC1, IRC2, Irp60" ENSG00000167851 "CD300a molecule" Q9UGN4 17 74466399-74484794 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 95.2" "Cell type enhanced" "Detected in some" "dendritic cells: 103.5;granulocytes: 59.5;Hofbauer cells: 114.0;Kupffer cells: 97.6;Macrophages: 90.9;NK-cells: 225.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "HMC-1: 104.4;NB-4: 45.9;RPMI-8226: 88.7" "HPA010971, HPA011645" Approved Approved "Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Vesicles, Cytosol" "HPA010971: , HPA011645: AB_1846988" "unprognostic (1.99e-1)" "unprognostic (4.60e-2)" "unprognostic (3.88e-2)" "unprognostic (3.30e-2)" "unprognostic (2.73e-1)" "unprognostic (2.01e-1)" "unprognostic (1.04e-2)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "unprognostic (1.17e-2)" "unprognostic (7.87e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (5.97e-2)" "unprognostic (5.45e-3)" "unprognostic (1.36e-1)" "unprognostic (5.72e-2)" 10.6 7.5 6.7 31.1 7.1 24.4 4.6 7.1 31.1 2.8 7.5 9.2 11.3 3.5 1.8 3.5 3.1 14.2 4.7 6.9 7.8 3.5 14.6 18.1 27.0 11.4 8.6 1.5 3.2 1.4 3.6 13.9 13.2 4.0 8.6 1.0 4.0 2.5 1.6 4.5 13.5 11.7 9.2 95.2 4.9 1.2 12.1 14.1 2.3 2.7 11.7 9.5 2.6 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 5.5 104.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 1.5 45.9 0.0 0.0 0.0 0.2 0.0 88.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 17.1 0.0 845.6 170.3 481.9 226.4 374.2 48.3 18.9 45.5 67.5 159.2 6.4 16.7 52.5 560.5 456.5 387.6 149.7 3.1 197.0 6.7 7.1 7.1 31.1 6.9 7.8 11.4 8.6 13.2 9.2 12.1 12.5 1.0 0.0 7.4 0.3 7.8 0.9 0.1 0.2 0.0 0.0 0.6 1.8 0.6 1.5 0.7 0.0 0.0 0.7 103.5 0.1 0.0 0.1 0.0 0.6 0.2 2.5 0.0 5.7 0.1 0.0 1.2 0.8 0.5 0.7 59.5 0.0 2.2 1.3 114.0 0.0 0.3 0.2 0.0 97.6 24.0 0.4 0.0 90.9 3.6 5.6 36.6 0.0 225.6 1.0 0.0 0.0 0.1 0.0 14.5 0.1 0.0 0.4 0.6 0.1 6.6 0.6 0.5 0.0 0.4 0.2 0.6 1.5 33.2 0.0 0.2 0.2 CD300C "CMRF-35A, CMRF35, CMRF35A, IGSF16, LIR" ENSG00000167850 "CD300c molecule" Q08708 17 74541073-74546115 "CD markers, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.7;lung: 8.4;lymphoid tissue: 7.3" "Group enriched" "Detected in some" 5 "granulocytes: 15.2;Hofbauer cells: 32.1;Kupffer cells: 26.3;Langerhans cells: 15.3;Macrophages: 36.1;monocytes: 19.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 228.3;non-classical monocyte: 242.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 7.1;HMC-1: 33.1;THP-1: 6.5;U-937: 16.2" "Low region specificity" "Detected in some" "HPA014523, HPA060349" Approved Uncertain "Golgi apparatus,Vesicles,Mitochondria" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus" "Vesicles, Mitochondria" "HPA014523: AB_1846293, HPA060349: " "unprognostic (1.55e-2)" "unprognostic (2.60e-1)" "unprognostic (9.99e-3)" "unprognostic (3.79e-1)" "unprognostic (1.21e-1)" "unprognostic (3.47e-2)" "unprognostic (3.81e-2)" "unprognostic (2.19e-1)" "unprognostic (1.68e-2)" "unprognostic (7.51e-2)" "unprognostic (6.51e-2)" "unprognostic (1.50e-2)" "unprognostic (1.37e-3)" "unprognostic (6.27e-2)" "prognostic unfavorable (8.53e-5)" "unprognostic (1.16e-2)" "unprognostic (1.09e-1)" 4.0 1.3 0.7 6.8 1.1 9.7 0.8 0.8 5.5 0.6 1.1 1.3 1.1 0.6 0.1 0.6 0.7 2.0 0.9 0.7 1.4 0.7 1.5 8.4 2.1 1.7 1.8 0.3 0.6 0.4 0.4 2.9 2.1 0.5 1.3 0.0 0.7 0.5 0.3 0.4 1.2 3.1 1.4 7.3 0.7 0.3 2.7 1.0 1.0 0.2 1.1 3.8 0.4 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 3.3 33.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.6 0.0 0.0 0.2 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.5 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.9 16.2 0.0 51.8 142.1 7.0 0.7 228.3 0.4 2.7 0.3 0.3 158.8 2.4 0.2 0.2 5.2 43.9 242.7 10.5 0.2 64.6 0.7 1.1 0.8 5.5 0.7 1.4 1.7 1.8 2.1 1.4 2.7 2.2 0.1 0.0 1.3 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.7 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.4 0.0 0.2 0.3 0.1 0.0 0.0 15.2 0.0 0.0 0.2 32.1 0.0 0.0 0.0 0.0 26.3 15.3 0.1 0.0 36.1 1.8 1.0 19.6 0.0 1.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.3 1.3 0.0 0.0 0.0 CD47 "IAP, MER6, OA3" ENSG00000196776 "CD47 molecule" Q08722 3 108043091-108091862 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 589.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016055, HPA044659" Approved Supported "Vesicles,Plasma membrane" NA NA 49000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" Vesicles "CAB016055: AB_627086, HPA044659: AB_2679040" "unprognostic (3.54e-2)" "unprognostic (4.74e-2)" "unprognostic (3.19e-2)" "prognostic unfavorable (2.44e-4)" "unprognostic (4.49e-2)" "unprognostic (2.14e-1)" "unprognostic (2.05e-3)" "unprognostic (8.77e-3)" "unprognostic (7.35e-2)" "unprognostic (1.53e-1)" "unprognostic (1.69e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (1.69e-4)" "unprognostic (7.37e-2)" "unprognostic (3.78e-1)" "prognostic favorable (7.29e-5)" "unprognostic (1.83e-1)" 51.8 64.9 39.2 116.4 47.9 232.2 89.3 64.4 63.5 57.4 30.4 89.0 74.6 53.0 92.4 93.9 100.5 86.7 59.5 47.2 41.9 44.4 71.4 154.6 137.9 53.1 40.5 46.1 41.5 27.2 34.6 80.1 48.5 122.2 99.3 285.7 105.3 55.7 57.9 59.8 79.3 55.4 50.9 100.1 104.2 59.0 49.2 79.1 91.2 22.8 161.7 110.1 52.4 76.4 303.3 49.9 108.0 62.1 130.3 122.6 147.9 106.0 139.4 70.8 126.0 2.1 159.1 129.6 180.0 90.7 216.5 201.0 52.2 98.7 91.7 81.5 35.8 311.6 45.9 3.9 73.8 227.4 467.6 85.7 58.1 71.6 53.6 118.5 73.4 132.6 85.1 323.6 108.5 148.1 268.5 77.0 46.7 298.4 133.6 154.2 69.3 187.8 185.3 115.8 69.7 37.9 63.6 111.7 124.4 56.5 227.4 85.8 76.5 210.9 40.9 120.7 79.4 124.2 100.8 208.0 131.5 119.8 65.6 185.2 119.2 232.8 178.1 244.2 155.6 191.6 209.7 192.0 181.6 188.7 149.2 169.0 145.4 232.6 339.2 133.3 334.5 296.9 39.2 47.9 64.4 63.5 47.2 41.9 53.1 40.5 48.5 50.9 49.2 76.4 72.3 368.6 157.4 98.6 192.9 165.3 311.7 504.4 101.3 102.9 119.0 93.1 51.9 110.1 205.7 93.8 95.9 169.9 218.6 36.5 15.6 589.6 81.5 157.2 17.0 76.5 63.8 112.6 219.2 412.5 85.5 119.1 36.2 120.4 57.7 250.0 83.6 34.2 186.4 122.8 129.3 70.8 148.5 79.6 200.7 52.2 34.2 121.5 117.4 39.4 100.5 51.7 219.4 107.1 150.4 344.7 92.6 48.5 143.8 439.0 53.7 16.3 162.2 229.7 65.7 47.1 85.4 111.5 19.6 97.1 140.1 121.2 160.8 80.6 94.3 321.3 CD59 "16.3A5, EJ16, EJ30, EL32, G344, MIC11, MIN1, MIN2, MIN3, MSK21, p18-20" ENSG00000085063 "CD59 molecule (CD59 blood group)" P13987 11 33703010-33736479 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 1445.2;Prostatic glandular cells: 1678.0;Urothelial cells: 1531.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 3747.5;U-2197: 3049.9" "CAB001448, HPA026494" Supported Uncertain "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 58000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus, Vesicles" "CAB001448: AB_563604, HPA026494: AB_1846321" "unprognostic (2.07e-2)" "prognostic unfavorable (3.81e-5)" "unprognostic (7.40e-2)" "unprognostic (1.14e-2)" "unprognostic (2.11e-2)" "prognostic unfavorable (3.10e-5)" "unprognostic (5.65e-2)" "unprognostic (1.46e-1)" "unprognostic (4.47e-2)" "unprognostic (2.98e-1)" "prognostic unfavorable (2.92e-5)" "unprognostic (1.66e-2)" "prognostic favorable (1.39e-10)" "prognostic unfavorable (9.03e-4)" "unprognostic (1.31e-1)" "unprognostic (1.03e-2)" "unprognostic (3.09e-1)" 517.4 248.3 284.5 209.6 310.8 198.8 555.9 329.0 365.1 305.5 542.2 255.1 120.7 290.7 971.7 478.9 368.1 475.3 608.3 288.2 359.7 577.4 339.8 553.5 148.8 327.9 340.2 228.5 353.6 706.1 250.3 485.6 340.9 256.8 271.4 130.7 693.6 443.2 529.3 282.8 167.9 380.0 330.5 131.8 422.7 127.7 337.0 167.7 308.1 915.0 288.6 550.5 325.5 315.6 297.2 278.4 77.6 212.0 1697.1 1314.9 46.8 1765.7 1778.5 408.9 451.9 129.7 822.1 23.9 291.5 1802.5 475.5 314.0 141.0 1589.9 561.1 475.5 218.2 31.3 846.7 193.1 483.2 183.4 94.8 631.8 387.2 343.3 1550.6 1104.9 2475.5 109.3 207.9 585.9 2575.4 282.7 79.9 70.3 43.5 541.8 1421.8 30.1 232.1 227.8 1304.4 510.0 54.3 79.5 576.2 243.7 298.2 218.0 187.5 18.1 3747.5 838.6 235.5 3049.9 595.9 273.8 558.8 30.4 734.2 1.3 1556.9 164.9 22.3 209.6 50.9 7.9 64.8 63.9 104.9 56.6 95.4 59.6 68.2 41.4 134.3 92.5 4.8 49.9 298.2 53.5 284.5 310.8 329.0 365.1 288.2 359.7 327.9 340.2 340.9 330.5 337.0 315.6 728.0 272.4 247.2 32.3 39.1 286.0 1103.2 951.4 82.0 51.3 434.9 270.0 315.5 444.7 569.7 242.8 33.3 553.5 29.2 344.6 164.4 1445.2 129.4 94.3 91.6 792.6 166.6 206.0 25.1 618.3 407.2 303.5 109.6 115.6 139.4 88.2 585.0 185.7 486.7 47.1 29.9 112.8 722.2 139.4 374.2 61.6 237.3 88.2 1270.0 54.4 161.7 198.3 26.8 32.6 22.2 1195.7 392.2 204.7 149.7 1678.0 41.7 208.2 1042.5 56.2 276.1 159.1 410.7 130.6 31.2 83.7 284.4 836.6 52.4 139.5 104.9 1531.0 CD63 "ME491, MLA1, TSPAN30" ENSG00000135404 "CD63 molecule" P08962 12 55725323-55729707 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 1857.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 4897.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010088, CAB026356, HPA073506" Supported Supported Vesicles "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB026356: AB_629864, HPA010088: AB_1846323, HPA073506: " "unprognostic (8.76e-3)" "unprognostic (8.81e-2)" "unprognostic (1.27e-1)" "unprognostic (1.28e-3)" "unprognostic (9.48e-2)" "unprognostic (3.66e-3)" "prognostic unfavorable (1.37e-4)" "unprognostic (1.11e-1)" "unprognostic (6.50e-2)" "unprognostic (1.08e-1)" "unprognostic (1.66e-2)" "unprognostic (3.10e-1)" "unprognostic (2.70e-2)" "unprognostic (4.82e-2)" "unprognostic (5.21e-2)" "unprognostic (1.85e-3)" "unprognostic (9.02e-2)" 954.0 882.1 509.4 457.9 526.5 747.2 769.6 532.6 717.1 715.6 611.8 809.3 394.5 854.6 1492.1 396.1 647.3 607.0 1152.2 508.5 565.7 625.3 565.1 882.2 325.0 564.7 539.9 645.9 830.1 524.7 486.6 588.0 544.3 520.0 736.0 269.1 871.6 547.4 919.3 410.0 559.3 744.5 534.9 597.7 790.8 224.3 583.6 193.3 657.7 587.4 284.9 835.3 539.7 561.7 481.0 669.0 432.6 430.8 4897.7 2932.4 577.5 1914.8 3104.6 979.2 1048.9 750.3 939.2 120.5 581.2 2608.7 787.7 436.3 301.7 732.6 1197.9 372.5 248.7 760.9 542.8 443.3 2006.7 338.5 1699.0 2315.1 639.7 1164.8 979.2 2305.1 1052.2 64.6 386.8 936.3 3062.5 626.3 64.1 439.5 395.7 1062.7 880.7 146.0 949.3 345.7 1699.3 1433.6 170.1 425.8 528.3 392.5 3348.6 630.4 546.4 1089.6 948.0 710.1 514.8 984.9 649.8 377.3 239.3 92.5 2023.9 208.1 1326.3 1279.9 610.3 1857.5 323.2 458.8 235.2 111.0 126.9 260.0 473.0 73.9 55.9 186.0 656.0 733.0 320.4 309.8 121.6 850.4 509.4 526.5 532.6 717.1 508.5 565.7 564.7 539.9 544.3 534.9 583.6 561.7 798.7 512.8 689.0 28.1 147.6 567.2 1382.5 3135.4 155.4 190.3 606.5 601.1 820.9 836.4 1789.7 875.4 152.2 608.3 322.0 1083.4 232.8 2621.2 16.7 446.7 766.7 916.3 581.1 97.0 8.8 3429.0 2756.5 1538.0 371.1 727.3 1030.0 531.6 739.6 423.9 3372.5 33.7 9.3 1251.6 1715.1 854.6 1698.3 65.5 1727.3 1146.7 1993.9 11.2 575.7 893.8 487.1 21.1 26.5 3437.4 1394.0 1157.0 326.9 2039.2 878.1 794.2 1012.6 258.8 1255.6 1845.2 1278.7 43.8 68.9 137.1 400.5 2708.1 310.4 645.8 761.6 1868.9 CD68 "DKFZp686M18236, GP110, LAMP4, macrosialin, SCARD1" ENSG00000129226 "CD68 molecule" P34810 17 7579491-7582111 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 358.0;lymphoid tissue: 370.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1820.4;Kupffer cells: 701.2;Langerhans cells: 341.5;Macrophages: 791.2;Proximal enterocytes: 335.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 3255.5;intermediate monocyte: 3655.9;non-classical monocyte: 3740.6" "Group enriched" "Detected in all" 11 "dendritic cells: 1378.6;monocytes: 3740.6" "Cell line enhanced" "Detected in all" "ASC diff: 472.0;U-87 MG: 751.0" "Low region specificity" "Detected in all" "CAB000051, CAB000066, HPA048982, CAB072861, CAB072862" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000051: AB_2314148, CAB000066: AB_2074844, CAB072861: AB_2665705, CAB072862: AB_2665706, HPA048982: AB_2680587" "unprognostic (2.16e-2)" "unprognostic (1.47e-2)" "unprognostic (6.46e-2)" "unprognostic (1.49e-3)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (4.75e-4)" "unprognostic (2.83e-2)" "unprognostic (1.31e-1)" "unprognostic (6.85e-2)" "unprognostic (1.04e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (1.14e-5)" "unprognostic (1.58e-1)" "unprognostic (8.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.65e-2)" 139.6 78.3 10.4 236.1 9.8 266.2 72.6 11.2 33.4 77.8 14.6 88.8 279.5 26.7 9.0 126.4 43.1 161.1 38.9 8.2 26.7 50.6 156.7 358.0 217.3 45.5 31.2 19.4 22.1 14.2 8.9 173.1 36.0 13.1 91.9 4.8 52.6 19.8 23.0 24.8 240.2 79.0 16.1 370.7 87.5 15.2 58.5 44.2 22.7 21.3 84.2 149.3 50.6 31.6 243.4 48.6 3.2 3.5 472.0 177.6 2.1 75.6 203.9 97.8 113.4 10.1 71.3 2.9 84.2 220.8 174.6 10.6 1.2 47.6 65.9 2.2 9.0 38.8 13.2 59.0 42.0 19.2 207.8 57.1 9.8 205.4 150.4 162.6 26.3 4.3 15.7 24.2 95.5 2.2 1.7 17.2 2.8 63.1 36.0 3.3 4.5 144.4 20.9 10.9 1.6 3.0 63.2 31.3 72.1 2.2 1.6 146.1 82.4 123.7 8.0 125.7 100.1 1.4 2.1 1.9 751.0 46.4 64.0 243.5 3255.5 21.4 9.1 3655.9 11.1 80.2 4.1 6.2 817.3 59.0 5.8 5.1 219.4 18.7 3740.6 1378.6 6.5 3324.3 10.4 9.8 11.2 33.4 8.2 26.7 45.5 31.2 36.0 16.1 58.5 31.6 10.4 0.0 19.7 1.3 20.5 15.7 39.0 58.8 3.4 0.2 7.2 9.8 0.0 12.8 53.2 5.5 0.0 8.9 110.3 22.5 5.9 82.1 0.8 8.3 11.3 15.9 4.9 6.6 0.3 156.8 58.1 45.6 29.6 18.7 43.6 0.9 16.4 23.9 1820.4 0.0 0.4 15.8 16.2 701.2 341.5 2.1 6.5 791.2 39.2 5.6 179.2 0.3 7.2 0.0 0.1 121.0 86.1 1.9 8.5 33.3 335.3 50.2 20.6 1.0 26.3 8.7 11.7 0.5 1.2 12.4 14.3 33.4 10.8 0.5 28.9 99.9 CD82 "IA4, KAI1, R2, ST6, TSPAN27" ENSG00000085117 "CD82 molecule" P27701 11 44564427-44620358 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 280.3;Proximal enterocytes: 220.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 536.4" "Group enriched" "Detected in all" 6 "B-cells: 310.1;granulocytes: 536.4;T-cells: 173.1" "Cell line enhanced" "Detected in many" "HMC-1: 463.8;U-87 MG: 323.3" "Region enhanced" "Detected in all" "white matter: 210.9" "Low region specificity" "Detected in all" "CAB002508, HPA028900, HPA061418" Supported Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "CAB002508: AB_563640, HPA028900: AB_10603558, HPA061418: AB_2684510" "unprognostic (5.31e-2)" "unprognostic (4.62e-1)" "unprognostic (2.38e-2)" "unprognostic (1.33e-1)" "unprognostic (2.79e-1)" "unprognostic (1.37e-2)" "unprognostic (1.78e-1)" "unprognostic (7.29e-2)" "unprognostic (3.48e-1)" "unprognostic (2.97e-1)" "unprognostic (2.58e-2)" "unprognostic (1.58e-1)" "unprognostic (3.48e-3)" "unprognostic (1.86e-3)" "unprognostic (2.33e-2)" "unprognostic (2.88e-2)" "unprognostic (6.30e-2)" 39.2 9.1 47.7 57.3 80.5 140.9 36.6 45.2 48.8 38.8 48.5 24.7 74.1 9.1 31.9 130.9 54.0 39.6 25.6 41.9 51.7 26.1 36.9 87.3 68.5 58.5 74.3 14.9 31.3 7.8 7.5 41.0 49.8 27.5 17.2 4.2 81.1 72.1 23.1 84.2 81.6 16.6 39.6 47.3 62.8 4.5 79.0 45.0 22.4 20.0 82.6 47.6 66.1 67.2 30.0 5.2 35.1 7.2 24.0 98.4 1.2 16.9 132.9 29.4 78.5 2.0 19.6 30.9 20.8 8.1 61.1 118.8 4.6 88.4 59.6 145.4 2.7 220.9 9.3 0.6 21.3 58.8 463.8 142.1 99.2 128.3 62.1 68.4 49.7 26.9 1.6 9.4 247.3 25.0 46.7 97.7 1.1 103.2 2.4 1.5 190.0 43.9 16.8 36.1 1.2 2.0 13.0 162.6 23.0 4.2 161.2 51.3 33.9 94.4 12.5 1.8 179.0 3.6 0.4 0.9 323.3 32.5 56.0 369.9 59.3 110.7 29.9 33.0 51.4 310.1 150.7 70.3 14.9 211.9 51.1 23.1 536.4 50.1 25.0 44.5 173.1 65.9 47.7 80.5 45.2 48.8 41.9 51.7 58.5 74.3 49.8 39.6 79.0 67.2 43.6 48.1 38.8 9.4 112.8 55.1 108.1 149.0 107.6 2.4 68.1 54.7 7.7 58.6 143.8 158.2 2.1 1.3 14.9 17.4 11.7 79.7 2.0 23.1 5.0 41.0 13.2 92.9 0.3 66.7 1.1 29.1 58.6 25.2 280.3 0.7 59.6 32.5 64.3 1.7 0.6 36.8 63.1 26.6 18.2 2.0 40.4 52.3 64.0 3.7 11.0 35.7 0.0 54.3 22.4 86.7 50.3 8.2 16.0 59.1 220.6 2.5 73.0 2.7 13.1 109.0 46.0 2.1 5.9 161.3 67.2 1.4 46.3 0.6 43.1 142.8 CD83 "BL11, HB15" ENSG00000112149 "CD83 molecule" Q01151 6 14117256-14136918 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 209.6" "Cell type enhanced" "Detected in many" "B-cells: 668.5;Langerhans cells: 1390.2;Macrophages: 539.4;monocytes: 513.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 79.1;HDLM-2: 71.9;U-698: 121.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002509, HPA041454, HPA073595" Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Vesicles "Golgi apparatus" "CAB002509: AB_563641, HPA041454: AB_2677489, HPA073595: " "unprognostic (2.22e-3)" "unprognostic (1.92e-2)" "unprognostic (1.22e-1)" "unprognostic (6.39e-2)" "unprognostic (5.83e-2)" "unprognostic (3.02e-2)" "unprognostic (1.00e-2)" "unprognostic (9.05e-3)" "unprognostic (9.05e-2)" "unprognostic (3.91e-2)" "unprognostic (7.37e-2)" "unprognostic (6.68e-2)" "prognostic favorable (3.49e-4)" "unprognostic (2.30e-1)" "unprognostic (7.07e-2)" "unprognostic (1.40e-2)" "unprognostic (2.46e-2)" 10.2 19.9 14.7 34.9 13.9 209.6 7.0 16.1 17.9 26.2 23.0 5.2 4.6 7.3 4.0 4.5 5.1 17.0 4.8 15.6 19.2 18.7 14.9 39.9 51.3 20.2 16.6 16.5 4.2 6.6 7.2 9.2 21.0 8.3 9.2 5.0 19.5 13.8 1.3 5.0 11.5 6.9 16.7 20.1 5.7 5.2 21.0 38.0 5.3 2.9 70.2 15.5 15.4 21.6 18.1 0.8 12.7 17.7 18.2 4.2 0.4 5.1 17.6 8.3 14.4 1.3 11.6 79.1 14.6 1.3 16.8 2.0 4.8 5.5 27.0 71.9 7.6 10.6 21.4 2.1 0.6 15.8 16.5 4.8 2.3 8.0 2.6 2.5 0.2 26.4 2.4 0.0 0.8 6.5 12.6 29.7 5.3 3.2 3.7 12.1 28.1 10.9 6.0 17.2 2.8 5.2 1.0 0.6 13.5 7.3 3.0 12.3 0.4 12.8 8.1 1.9 12.0 0.7 0.2 121.5 2.8 21.6 19.7 0.0 3.1 2.0 4.4 19.0 4.8 19.7 4.0 3.7 9.0 31.0 2.8 3.3 2.2 5.0 29.3 3.2 6.2 4.4 14.7 13.9 16.1 17.9 15.6 19.2 20.2 16.6 21.0 16.7 21.0 21.6 41.3 19.2 77.9 5.2 668.5 49.5 16.0 10.0 41.5 4.2 26.5 46.4 30.9 2.8 8.2 11.0 6.2 1.5 100.4 5.4 3.9 0.9 0.9 29.0 24.1 39.1 24.0 3.0 5.6 1.6 2.4 31.1 11.2 74.8 238.8 8.1 2.9 1.1 145.6 1.7 6.1 7.3 4.1 83.0 1390.2 1.9 0.3 539.4 44.4 13.1 513.6 3.5 1.0 2.5 1.3 2.1 0.4 0.0 20.4 26.2 1.7 17.7 4.9 2.7 0.0 17.2 17.0 2.1 10.2 17.2 38.5 2.7 69.2 21.0 11.6 3.5 CD84 "hCD84, mCD84, SLAMF5" ENSG00000066294 "CD84 molecule" Q9UIB8 1 160541095-160579516 "CD markers, Predicted membrane proteins" "Adaptive immunity, Autophagy, Cell adhesion, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.2" "Cell type enhanced" "Detected in many" "granulocytes: 187.1;Hofbauer cells: 91.1;Kupffer cells: 177.0;Macrophages: 90.6;monocytes: 76.4;T-cells: 46.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 23.8;HEL: 45.3;HL-60: 13.1;HMC-1: 49.7;MOLT-4: 12.9;U-698: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063316, HPA068020, HPA070502" Enhanced Enhanced "Vesicles,Plasma membrane" NA NA 35000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" Vesicles "HPA063316: , HPA068020: , HPA070502: AB_2686274" "unprognostic (4.38e-2)" "unprognostic (6.16e-3)" "unprognostic (1.00e-2)" "unprognostic (8.16e-2)" "unprognostic (2.35e-1)" "unprognostic (2.00e-2)" "unprognostic (3.84e-1)" "unprognostic (2.54e-2)" "unprognostic (8.60e-2)" "unprognostic (1.80e-1)" "unprognostic (8.26e-2)" "unprognostic (1.57e-1)" "unprognostic (1.30e-2)" "unprognostic (2.15e-1)" "unprognostic (4.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.08e-1)" 3.3 2.4 1.9 19.4 2.1 7.9 2.7 2.3 2.4 2.8 1.9 3.2 2.4 1.4 0.9 2.2 1.1 6.2 1.4 1.7 1.9 0.8 5.2 7.8 24.2 5.2 3.1 1.5 2.0 0.9 0.4 7.1 4.5 1.1 4.5 0.2 1.4 3.4 0.4 1.3 4.6 4.0 3.8 15.2 3.6 1.9 5.2 9.9 1.1 0.7 13.2 4.7 0.8 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 45.3 0.1 0.0 0.0 13.1 49.7 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.9 0.1 0.0 0.0 12.9 9.7 0.0 0.0 0.0 0.4 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 30.8 0.0 2.9 0.0 32.7 9.6 15.0 8.2 8.0 6.5 6.3 7.0 10.1 7.1 6.0 4.0 7.4 1.2 1.4 3.2 4.1 10.5 8.8 1.9 2.1 2.3 2.4 1.7 1.9 5.2 3.1 4.5 3.8 5.2 7.2 1.3 0.0 6.4 0.0 27.4 2.4 0.7 0.0 0.6 0.2 0.6 1.5 1.2 2.8 1.3 0.0 0.0 0.5 20.5 0.2 0.0 0.1 0.9 0.5 0.2 4.2 0.0 21.5 0.1 0.2 0.5 1.2 2.6 0.2 187.1 0.1 3.3 1.1 91.1 0.0 0.2 0.1 0.0 177.0 42.2 1.5 0.6 90.6 5.4 34.7 76.4 0.0 4.1 0.0 0.1 0.0 0.0 0.0 10.8 0.9 0.3 0.3 0.7 0.2 0.0 1.6 1.5 0.1 0.4 0.5 2.4 1.0 46.8 2.9 0.2 0.6 CD93 "C1qR(P), C1QR1, C1qRP, CDw93, dJ737E23.1, ECSM3, MXRA4" ENSG00000125810 "CD93 molecule" Q9NPY3 20 23079360-23086324 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 137.6" "Cell type enhanced" "Detected in many" "Adipocytes: 321.5;Endothelial cells: 309.2;Hepatic stellate cells: 162.8;Kupffer cells: 156.4;Macrophages: 102.4;monocytes: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "classical monocyte: 25.8;intermediate monocyte: 16.8;myeloid DC: 9.1;neutrophil: 27.8;non-classical monocyte: 7.5" "Group enriched" "Detected in many" 41 "dendritic cells: 9.1;granulocytes: 27.8;monocytes: 25.8" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 346.0;TIME: 442.2;U-937: 593.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009300, HPA012368" Enhanced Approved "Vesicles,Plasma membrane" NA NA 550000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 32: U-937 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" "HPA009300: AB_1846342, HPA012368: AB_1846341" "unprognostic (2.05e-1)" "unprognostic (2.85e-1)" "unprognostic (1.07e-1)" "unprognostic (4.83e-2)" "unprognostic (2.31e-1)" "unprognostic (2.66e-2)" "unprognostic (6.45e-2)" "unprognostic (2.77e-1)" "unprognostic (4.51e-1)" "unprognostic (3.74e-2)" "unprognostic (2.61e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (2.74e-4)" "unprognostic (8.81e-3)" "unprognostic (6.13e-2)" "unprognostic (4.49e-2)" "unprognostic (3.11e-2)" 81.4 11.9 2.7 43.5 2.6 16.4 41.0 2.8 6.5 23.9 6.5 13.8 9.8 17.8 6.1 19.0 23.4 39.7 34.3 2.7 3.5 25.6 16.3 64.6 14.0 5.4 4.3 6.2 13.2 10.8 6.6 137.6 5.4 11.3 12.1 1.4 9.7 10.9 24.2 12.2 14.5 43.5 4.0 23.4 13.0 4.6 7.1 9.3 21.4 34.4 10.6 41.3 12.8 3.5 0.2 0.0 4.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 346.0 0.0 0.9 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.9 0.2 27.8 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 105.3 442.2 0.0 0.1 0.1 0.5 0.0 0.0 0.3 0.0 593.5 0.1 0.0 25.8 0.4 0.3 16.8 0.0 0.0 0.2 0.1 9.1 0.0 0.0 0.0 27.8 0.1 7.5 1.2 0.5 9.9 2.7 2.6 2.8 6.5 2.7 3.5 5.4 4.3 5.4 4.0 7.1 3.5 321.5 3.2 7.4 0.0 2.4 15.0 1.0 0.0 6.2 0.0 1.0 1.8 14.3 5.7 3.7 0.0 0.0 0.2 5.0 0.0 0.0 0.5 0.4 0.4 0.7 309.2 0.0 1.3 0.0 0.0 0.5 9.8 0.5 0.4 5.1 0.0 162.8 1.9 19.9 0.0 0.2 0.0 0.0 156.4 52.5 0.8 1.8 102.4 8.8 4.7 131.8 0.2 6.2 0.0 0.1 0.1 0.0 27.8 2.1 4.1 0.0 0.3 3.0 0.1 19.7 5.7 8.0 0.0 0.2 1.6 10.1 0.4 2.4 3.0 0.0 4.0 CDC25B ENSG00000101224 "Cell division cycle 25B" P30305 20 3786772-3806121 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 7.2;NK-cells: 18.1;T-cells: 28.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038892, HPA038893, HPA075215" Enhanced Uncertain "Vesicles,Mitotic spindle" Yes Yes "Cluster 20: T-cells - T-cell receptor" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Mitotic spindle" "HPA038892: AB_2676258, HPA038893: AB_2676259, HPA075215: " "unprognostic (4.69e-2)" "unprognostic (5.74e-2)" "unprognostic (2.93e-2)" "prognostic unfavorable (4.76e-4)" "unprognostic (1.13e-1)" "unprognostic (4.23e-1)" "prognostic unfavorable (1.19e-4)" "unprognostic (1.31e-2)" "unprognostic (4.92e-2)" "unprognostic (2.74e-1)" "unprognostic (1.67e-1)" "unprognostic (6.03e-2)" "prognostic unfavorable (2.94e-13)" "unprognostic (1.15e-1)" "unprognostic (2.38e-1)" "unprognostic (3.94e-1)" "unprognostic (9.46e-2)" 29.2 15.6 30.5 28.8 32.4 29.4 25.1 39.2 33.2 41.7 23.2 37.6 14.4 35.0 9.4 27.1 31.5 17.9 16.3 27.6 32.5 31.3 24.8 78.4 47.6 31.3 29.9 37.4 12.8 3.8 45.7 31.1 30.2 25.4 11.3 7.8 16.7 8.9 10.5 21.8 41.2 14.2 27.4 56.1 30.1 12.4 30.9 44.7 41.8 6.3 32.8 35.8 30.2 35.8 129.6 273.2 36.5 60.0 43.8 43.0 19.3 63.3 95.3 103.1 75.9 49.2 182.9 91.3 27.5 65.4 253.5 183.5 50.6 105.8 50.2 36.2 54.4 49.4 88.5 59.6 178.4 38.6 25.0 41.1 85.0 95.4 115.7 35.6 58.4 44.2 33.3 232.7 63.1 105.5 119.0 57.7 27.3 90.9 116.9 62.0 102.6 67.5 73.2 12.2 25.8 56.9 148.6 140.8 78.1 31.7 48.1 20.4 48.6 55.1 66.2 101.5 85.0 57.8 97.8 36.8 28.1 38.0 54.6 3.9 2.4 0.0 22.7 3.4 21.3 5.8 22.6 23.3 2.4 7.2 18.6 21.6 0.3 18.1 1.7 1.3 28.2 11.2 30.5 32.4 39.2 33.2 27.6 32.5 31.3 29.9 30.2 27.4 30.9 35.8 14.0 9.6 21.7 18.6 21.7 11.2 6.0 10.9 7.4 14.4 4.8 5.5 8.6 8.6 4.5 7.3 2.1 11.9 30.6 5.8 0.0 9.9 0.7 2.7 20.6 27.1 7.8 32.6 39.2 4.8 17.7 15.7 17.3 5.4 1.3 11.5 14.3 13.7 30.4 3.3 38.0 10.4 12.2 14.8 9.4 1.1 7.2 12.4 17.8 6.5 8.8 8.3 44.3 22.6 13.2 15.0 4.3 9.1 49.6 6.0 5.5 11.1 3.7 2.6 0.0 26.5 14.0 2.3 12.3 10.3 11.2 3.6 36.4 7.1 10.9 4.4 CDH12 "Br-cadherin, CDHB" ENSG00000154162 "Cadherin 12" P55289 5 21750673-22853344 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.6;retina: 11.6" "Group enriched" "Detected in some" 15 "Excitatory neurons: 859.5;Inhibitory neurons: 887.7" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in some" 5 "basal ganglia: 6.6;cerebral cortex: 3.8;hippocampal formation: 2.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "PC-3: 2.2;SCLC-21H: 3.1;U-2 OS: 1.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029325 Uncertain Uncertain Vesicles NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA029325: AB_2672998" "unprognostic (2.38e-1)" "unprognostic (3.21e-1)" "unprognostic (4.95e-2)" "unprognostic (8.61e-2)" "unprognostic (3.31e-2)" "unprognostic (3.91e-1)" "unprognostic (2.72e-1)" "unprognostic (3.26e-2)" "unprognostic (1.34e-1)" "unprognostic (3.51e-2)" "unprognostic (3.25e-4)" "unprognostic (7.35e-2)" "unprognostic (3.48e-2)" "unprognostic (5.19e-2)" 0.0 2.0 0.8 0.0 6.6 0.0 0.5 0.2 3.8 3.0 2.1 0.0 0.0 0.3 0.2 0.0 2.2 0.0 0.0 2.0 0.0 0.1 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 1.4 0.1 0.8 0.0 0.1 11.6 1.4 0.2 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 6.6 0.2 3.8 2.0 0.0 0.5 0.0 0.8 0.0 0.0 0.7 0.4 0.0 0.0 41.4 0.0 0.1 0.0 0.0 0.0 25.1 0.4 0.6 0.9 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.1 2.1 0.0 0.0 859.5 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.0 0.0 20.2 887.7 0.0 0.0 0.0 0.4 0.3 0.3 0.0 0.0 15.9 0.0 2.2 0.0 31.2 41.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.1 0.0 0.2 0.0 2.6 1.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 CDH24 CDH11L ENSG00000139880 "Cadherin 24" Q86UP0 14 23047062-23057538 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 11.7;Astrocytes: 9.1;Bipolar cells: 8.2;Endothelial cells: 8.8;Enteroendocrine cells: 10.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 52.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074551 Approved Vesicles,Cytosol NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol Vesicles "HPA074551: " "unprognostic (2.30e-1)" "unprognostic (3.06e-2)" "unprognostic (4.15e-3)" "unprognostic (6.21e-2)" "unprognostic (1.27e-1)" "unprognostic (9.18e-2)" "unprognostic (6.68e-3)" "unprognostic (2.71e-2)" "unprognostic (5.97e-3)" "unprognostic (3.55e-1)" "unprognostic (4.18e-2)" "unprognostic (5.97e-2)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.27e-1)" "unprognostic (1.43e-1)" "unprognostic (1.37e-2)" "unprognostic (8.85e-2)" 4.3 2.4 4.9 1.2 3.8 1.2 3.6 3.8 4.7 5.9 1.7 2.7 1.1 8.6 1.1 4.0 4.3 4.2 2.0 9.4 4.3 2.9 0.5 3.3 1.3 4.0 3.9 2.4 2.1 2.2 1.9 1.6 3.9 3.1 1.7 1.7 3.1 1.6 0.7 2.9 2.4 4.0 2.3 2.4 2.0 1.7 3.8 3.7 4.6 0.5 0.9 2.6 4.1 5.3 4.6 4.5 18.3 20.9 4.4 2.2 10.1 8.4 5.4 7.0 9.0 5.7 6.1 0.3 6.7 9.2 1.8 25.8 8.0 7.1 5.6 7.1 6.7 1.0 12.7 1.9 4.9 13.2 0.3 17.3 2.3 7.6 5.0 8.5 11.5 4.2 2.9 11.0 6.1 12.9 1.0 8.8 4.6 4.7 10.2 22.9 6.1 8.4 2.0 3.8 52.9 14.2 19.7 10.4 1.1 5.0 9.3 1.9 10.7 6.9 26.0 2.8 6.3 3.5 1.1 0.3 7.2 3.8 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 3.8 3.8 4.7 9.4 4.3 4.0 3.9 3.9 2.3 3.8 5.3 11.7 0.0 0.0 9.1 0.3 1.5 0.8 0.5 3.4 8.2 2.1 1.1 2.0 0.0 0.5 1.8 0.0 2.3 0.9 1.9 1.9 0.5 0.4 0.6 2.1 8.8 10.7 0.0 2.6 0.5 2.5 1.7 1.1 1.0 0.0 4.3 2.5 0.0 0.6 0.0 1.7 1.7 0.0 0.0 0.3 1.0 0.0 0.1 1.8 2.8 0.1 4.4 0.0 5.5 0.2 0.6 0.3 0.0 0.3 0.8 0.2 0.5 0.5 0.8 0.0 0.2 1.5 1.1 2.5 2.0 2.3 1.9 0.7 2.5 2.1 0.9 CDK5R1 "Nck5a, p35, p35nck5a" ENSG00000176749 "Cyclin dependent kinase 5 regulatory subunit 1" Q15078 17 32486993-32491253 "Predicted intracellular proteins" "Biological rhythms" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 63.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 45.9;Early spermatids: 21.2;Excitatory neurons: 36.6;Inhibitory neurons: 31.6;Late spermatids: 18.9" "Cancer enhanced" "Detected in many" "melanoma: 14.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "SCLC-21H: 58.1;SH-SY5Y: 15.6;SK-MEL-30: 43.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000252 Approved Nucleoplasm,Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "HPA000252: AB_2665953" "unprognostic (1.08e-1)" "unprognostic (9.13e-2)" "unprognostic (1.79e-2)" "unprognostic (3.65e-1)" "unprognostic (1.97e-1)" "unprognostic (8.09e-2)" "unprognostic (2.74e-5)" "unprognostic (1.81e-2)" "unprognostic (3.32e-1)" "unprognostic (2.18e-1)" "unprognostic (5.90e-2)" "unprognostic (5.60e-1)" "unprognostic (6.98e-2)" "unprognostic (1.60e-1)" "unprognostic (7.92e-2)" "unprognostic (8.81e-2)" "unprognostic (1.03e-1)" 0.8 2.8 37.8 7.1 50.8 5.4 1.2 11.0 63.5 1.5 0.0 0.9 1.4 0.9 0.2 7.5 0.7 0.9 1.1 53.4 21.1 0.8 1.0 0.8 13.9 3.2 10.5 2.6 1.4 0.7 6.9 0.6 4.5 0.6 0.8 10.4 1.1 0.5 2.3 1.9 3.6 0.6 3.5 12.1 1.6 7.2 21.7 4.2 0.5 0.8 14.1 0.8 3.1 34.2 3.9 2.2 9.8 3.1 1.1 1.8 1.1 2.4 1.4 2.9 3.7 5.7 0.9 1.9 2.2 2.0 2.4 1.8 3.8 2.4 3.8 0.7 7.3 0.7 1.1 2.3 0.5 1.3 1.9 1.1 5.8 2.9 2.4 1.1 2.1 6.9 3.9 2.2 6.2 1.6 3.4 1.5 6.2 1.4 2.1 2.9 5.9 7.1 1.4 1.7 58.1 15.6 2.3 1.3 43.8 1.4 2.5 4.4 2.2 4.0 5.9 1.6 6.3 1.1 1.5 1.9 3.4 5.6 9.7 0.0 0.3 0.4 0.8 0.3 0.6 0.2 1.1 0.4 0.0 0.1 1.5 0.9 1.2 0.2 0.1 0.6 0.1 0.6 37.8 50.8 11.0 63.5 53.4 21.1 3.2 10.5 4.5 3.5 21.7 34.2 1.7 0.0 1.5 6.5 13.1 1.5 0.5 1.0 7.4 15.9 3.7 2.3 3.6 0.0 0.8 0.0 45.9 0.6 10.1 0.3 0.0 0.2 21.2 1.1 1.3 1.2 0.0 0.0 36.6 0.6 0.3 1.2 0.5 1.5 0.0 1.6 0.7 0.7 0.9 1.7 31.6 1.4 2.0 3.5 0.5 18.9 0.0 1.3 3.6 2.8 2.0 18.4 10.3 9.5 11.9 1.2 1.2 0.7 0.9 1.2 0.4 1.5 1.0 6.3 0.0 2.9 3.1 6.7 4.3 8.8 1.3 1.1 7.1 1.9 1.1 0.5 CDK5RAP3 "C53, FLJ13660, HSF-27, IC53, LZAP, MST016, OK/SW-cl.114" ENSG00000108465 "CDK5 regulatory subunit associated protein 3" Q96JB5 17 47967810-47981781 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022141, HPA022882, HPA027883" Supported Supported Nucleoli,Vesicles,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Nucleoli, Vesicles" "HPA022141: AB_1846426, HPA022882: AB_1846428, HPA027883: AB_10602797" "unprognostic (4.27e-2)" "unprognostic (1.01e-3)" "unprognostic (9.95e-3)" "unprognostic (6.65e-2)" "unprognostic (5.98e-2)" "unprognostic (7.19e-3)" "unprognostic (3.84e-1)" "unprognostic (4.44e-2)" "unprognostic (7.55e-2)" "unprognostic (2.06e-1)" "unprognostic (2.59e-3)" "unprognostic (1.92e-2)" "prognostic unfavorable (3.61e-5)" "unprognostic (8.35e-3)" "unprognostic (2.30e-1)" "unprognostic (9.58e-2)" "prognostic favorable (7.31e-5)" 45.8 48.2 83.8 42.0 85.7 52.3 48.7 83.7 111.3 58.1 100.4 53.0 54.5 42.4 91.9 52.8 54.2 46.1 39.2 85.5 85.5 60.2 80.6 44.6 51.7 86.4 84.7 69.5 133.6 53.6 93.0 34.3 85.7 62.6 53.8 34.1 77.0 48.5 29.6 43.5 68.5 33.8 83.1 81.4 81.8 83.5 86.6 44.2 73.2 28.1 54.8 48.1 48.3 86.7 72.7 116.5 60.8 114.6 52.6 53.3 112.7 51.4 63.9 52.3 51.0 92.5 72.3 88.7 107.8 55.5 35.2 72.8 41.6 61.4 59.3 127.0 58.1 43.4 157.9 123.8 58.7 50.0 47.5 60.7 51.5 45.9 91.8 64.2 52.8 169.1 49.6 80.8 52.9 140.3 128.3 79.2 38.5 87.4 55.0 74.6 101.4 101.7 52.8 91.3 43.0 104.1 38.3 37.1 51.7 65.3 84.5 65.4 38.9 43.6 38.2 53.1 66.8 106.8 102.9 54.2 54.3 69.1 53.5 20.8 62.6 54.8 33.8 63.8 36.8 40.9 31.4 30.6 50.1 44.7 28.0 31.4 30.5 45.3 67.4 46.0 32.9 41.3 83.8 85.7 83.7 111.3 85.5 85.5 86.4 84.7 85.7 83.1 86.6 86.7 31.3 25.6 62.6 60.7 61.8 33.6 63.3 89.3 50.7 52.0 52.8 40.4 28.4 44.3 84.1 40.5 31.3 68.8 44.9 56.5 50.9 56.8 53.0 35.7 32.9 32.1 61.6 22.9 31.1 67.7 57.4 44.7 147.8 42.5 69.6 68.3 27.5 55.6 61.7 57.2 27.9 70.8 71.2 33.6 40.7 36.3 40.7 44.1 46.2 25.3 47.6 45.1 33.0 25.6 50.6 37.1 60.9 29.7 87.2 49.0 77.2 45.1 85.2 52.6 32.9 34.3 33.2 132.8 45.7 31.0 25.9 61.6 53.0 38.6 56.8 56.6 CDKL1 KKIALRE ENSG00000100490 "Cyclin dependent kinase like 1" Q00532 14 50326265-50416461 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 23.4;Excitatory neurons: 46.2;Oligodendrocyte precursor cells: 46.8;Oligodendrocytes: 25.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SK-BR-3: 18.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059605, HPA065919" Uncertain Enhanced Nucleoplasm,Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Vesicles "HPA059605: AB_2684080, HPA065919: AB_2685578" "unprognostic (4.12e-3)" "unprognostic (3.22e-1)" "unprognostic (4.54e-2)" "unprognostic (8.04e-2)" "unprognostic (1.64e-2)" "unprognostic (1.02e-1)" "unprognostic (3.23e-3)" "unprognostic (9.36e-3)" "unprognostic (2.63e-1)" "unprognostic (9.99e-2)" "unprognostic (1.20e-1)" "unprognostic (9.36e-2)" "unprognostic (5.53e-8)" "unprognostic (1.21e-1)" "unprognostic (7.96e-2)" "unprognostic (9.39e-3)" "unprognostic (3.31e-3)" 13.5 3.6 3.4 4.9 4.4 3.6 3.5 1.4 9.0 13.9 3.7 8.8 13.2 13.9 3.2 5.2 15.4 5.2 2.3 5.5 2.3 19.4 1.6 6.5 6.5 2.0 2.1 13.8 1.3 1.2 0.6 6.5 2.9 5.9 6.6 20.2 2.8 9.0 7.1 13.5 6.9 8.5 2.9 7.0 4.9 2.0 1.8 1.9 7.9 1.0 2.6 6.9 6.6 8.1 7.7 4.9 3.5 4.3 5.3 6.1 2.3 2.2 3.2 1.9 2.0 4.0 5.9 6.1 2.8 3.2 3.2 5.9 0.8 0.3 1.9 8.9 3.1 12.2 4.6 3.9 6.2 9.7 5.3 1.5 3.0 3.2 8.0 2.4 6.7 10.3 3.3 4.8 1.1 2.5 2.8 4.7 1.9 2.6 3.9 3.3 3.8 3.1 5.3 6.6 4.6 3.4 4.2 18.3 2.1 1.3 2.4 6.2 4.0 6.7 4.1 7.1 5.0 2.4 1.8 2.9 1.7 8.7 7.6 3.2 1.4 2.6 3.5 1.4 3.1 2.6 2.3 3.2 0.8 3.0 1.9 1.9 0.7 2.3 0.2 0.8 2.4 1.3 3.4 4.4 1.4 9.0 5.5 2.3 2.0 2.1 2.9 2.9 1.8 8.1 3.2 19.2 9.9 6.5 3.0 3.1 4.1 0.2 3.4 0.7 0.4 0.5 0.5 0.0 2.6 11.0 0.0 0.1 2.3 7.2 5.9 1.4 0.4 23.4 9.6 3.3 1.8 6.1 46.2 1.8 0.1 7.6 1.1 4.9 1.3 3.2 6.4 0.3 0.4 0.0 20.6 2.1 2.0 0.9 1.5 1.5 9.0 1.5 0.0 7.5 0.8 0.9 2.1 46.8 25.4 1.9 4.8 3.4 0.2 3.1 4.9 8.0 20.4 0.7 0.0 4.0 4.6 0.0 0.3 4.7 2.7 0.3 4.2 3.6 5.2 2.2 CDKL3 NKIAMRE ENSG00000006837 "Cyclin dependent kinase like 3" Q8IVW4 5 134286350-134371047 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 16.2" "Group enriched" "Detected in many" 6 "Early spermatids: 342.0;Late spermatids: 295.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027751 Uncertain Nucleoplasm,Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Vesicles" "HPA027751: AB_10601256" "unprognostic (4.70e-2)" "unprognostic (2.15e-2)" "unprognostic (2.35e-1)" "unprognostic (1.48e-1)" "unprognostic (1.43e-1)" "unprognostic (3.98e-2)" "unprognostic (3.43e-3)" "unprognostic (5.93e-2)" "unprognostic (2.12e-3)" "unprognostic (1.49e-1)" "unprognostic (8.47e-4)" "unprognostic (2.82e-1)" "unprognostic (9.85e-4)" "unprognostic (8.33e-2)" "unprognostic (4.88e-2)" "unprognostic (7.10e-3)" "unprognostic (3.43e-3)" 0.7 0.8 2.5 0.5 2.8 0.2 0.6 2.5 4.4 0.8 1.3 0.8 0.5 1.1 0.6 0.6 1.2 0.6 2.7 2.4 2.7 1.5 0.8 0.5 0.7 2.9 2.6 0.7 0.5 1.0 0.6 0.4 3.0 0.7 0.6 4.2 0.4 0.8 3.4 0.6 0.6 1.5 3.1 0.7 0.5 16.2 2.8 0.9 1.2 3.3 0.9 0.6 0.5 5.0 0.5 1.3 1.7 1.2 2.7 2.4 0.7 1.7 1.4 0.7 1.7 1.2 0.8 1.3 1.0 1.1 3.3 0.5 1.5 1.0 1.2 1.6 1.0 0.8 1.7 1.9 1.7 0.3 0.5 1.1 2.5 2.2 0.6 1.2 0.7 3.4 1.1 0.7 1.9 0.6 1.2 4.6 1.2 0.3 0.5 1.9 0.6 0.4 0.9 0.5 2.5 0.8 1.8 0.1 2.1 1.8 1.0 0.9 0.5 1.4 0.3 1.9 0.5 1.8 2.5 2.9 2.1 1.4 1.1 0.0 0.3 0.3 0.3 0.4 1.4 0.5 0.4 0.9 1.0 0.3 1.3 1.3 0.0 0.6 0.1 0.5 0.9 0.4 2.5 2.8 2.5 4.4 2.4 2.7 2.9 2.6 3.0 3.1 2.8 5.0 4.1 0.0 3.7 50.6 2.0 10.8 6.4 18.8 4.0 13.3 4.5 5.8 2.2 2.8 9.9 5.5 4.2 3.1 3.2 0.5 9.8 3.5 342.0 7.5 6.4 4.6 3.0 4.8 41.6 5.1 1.8 6.2 1.5 3.7 3.8 7.0 3.6 2.3 3.6 6.7 52.0 1.5 18.3 2.1 19.4 295.3 5.0 2.8 10.6 16.9 2.4 10.8 3.1 32.6 50.7 1.5 1.6 9.1 1.4 4.3 1.3 9.5 12.9 9.7 0.0 6.3 7.9 35.3 17.2 1.7 11.1 4.5 3.4 6.2 0.9 3.8 CDKN1B "KIP1, P27KIP1" ENSG00000111276 "Cyclin dependent kinase inhibitor 1B" P46527 12 12715058-12722369 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Protein kinase inhibitor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 182.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003691, CAB021888, HPA059086" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Vesicles "CAB003691: AB_425362, CAB021888: , HPA059086: AB_2683900" "unprognostic (5.67e-2)" "unprognostic (9.76e-2)" "prognostic favorable (5.15e-4)" "unprognostic (6.90e-3)" "unprognostic (5.84e-3)" "unprognostic (1.03e-2)" "prognostic unfavorable (3.25e-4)" "unprognostic (4.04e-2)" "unprognostic (1.11e-1)" "unprognostic (2.85e-3)" "unprognostic (9.23e-3)" "unprognostic (2.96e-1)" "prognostic unfavorable (8.39e-4)" "unprognostic (1.23e-1)" "unprognostic (8.68e-2)" "unprognostic (2.88e-1)" "unprognostic (1.15e-1)" 53.4 44.7 53.6 40.1 70.6 68.1 50.2 73.4 81.3 55.3 43.1 43.9 44.5 41.0 24.5 29.1 47.3 24.6 32.9 47.9 58.9 30.2 35.2 38.9 55.3 58.6 58.3 66.1 23.9 34.4 24.4 41.0 61.2 35.9 32.5 55.3 36.3 33.4 81.4 45.4 40.7 24.8 55.1 55.1 30.0 25.8 58.3 71.8 33.7 63.4 39.9 32.0 44.5 91.2 37.1 16.6 94.5 16.6 32.0 18.0 46.1 31.5 53.8 46.0 56.4 47.7 40.4 0.3 12.5 19.6 16.6 34.2 44.9 16.7 41.1 62.4 31.5 28.8 46.5 53.2 42.5 24.5 18.6 19.8 35.3 15.2 44.0 107.8 27.8 54.5 31.5 101.6 16.6 45.9 32.7 35.3 38.0 32.1 16.8 25.2 30.9 63.1 22.5 38.6 35.6 58.4 48.9 34.8 65.8 33.7 18.6 54.6 19.1 22.6 34.9 20.7 33.3 86.1 59.4 33.2 28.2 36.6 22.5 6.2 3.8 8.6 5.9 3.5 6.1 6.8 7.7 7.2 3.6 5.0 8.0 6.1 20.9 7.3 5.5 3.9 12.3 4.0 53.6 70.6 73.4 81.3 47.9 58.9 58.6 58.3 61.2 55.1 58.3 91.2 64.2 44.8 29.3 6.2 126.2 52.6 20.7 21.0 115.5 45.6 39.5 30.1 39.1 21.5 27.1 9.2 27.1 42.9 92.5 32.3 15.6 10.8 70.0 31.2 35.8 51.1 45.7 70.5 8.1 9.3 47.6 39.3 25.5 34.3 31.0 21.3 47.2 30.7 26.8 10.1 13.4 41.4 24.4 55.3 66.0 67.7 55.9 65.1 74.7 23.4 31.6 182.9 60.8 6.0 29.5 10.1 21.3 26.7 121.2 30.3 33.4 16.9 36.4 29.4 92.1 20.2 53.5 7.7 10.8 102.3 52.6 39.0 166.1 20.9 41.9 22.7 CEBPA "C/EBP-alpha, CEBP" ENSG00000245848 "CCAAT enhancer binding protein alpha" P49715 19 33299934-33302534 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 98.7;liver: 194.7;skin 1: 118.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 91.6;Hepatocytes: 106.5;Hofbauer cells: 87.0;Suprabasal keratinocytes: 171.8;Syncytiotrophoblasts: 212.3" "Cancer enhanced" "Detected in all" "liver cancer: 70.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 16.0;classical monocyte: 7.1;intermediate monocyte: 12.3;myeloid DC: 5.1;non-classical monocyte: 15.7" "Group enriched" "Detected in many" 15 "dendritic cells: 5.1;granulocytes: 16.0;monocytes: 15.7" "Cell line enhanced" "Detected in many" "BEWO: 196.9;Hep G2: 110.9;NB-4: 114.1;THP-1: 407.7;U-937: 130.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052734, HPA065037, HPA067937" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA052734: AB_2681931, HPA065037: AB_2685410, HPA067937: AB_2685927" "unprognostic (1.80e-1)" "unprognostic (7.62e-3)" "unprognostic (2.09e-3)" "unprognostic (2.21e-2)" "unprognostic (3.38e-1)" "unprognostic (3.99e-2)" "unprognostic (1.94e-1)" "unprognostic (2.43e-3)" "unprognostic (5.95e-2)" "unprognostic (3.96e-2)" "unprognostic (3.09e-1)" "unprognostic (9.45e-2)" "unprognostic (8.02e-3)" "unprognostic (2.19e-1)" "unprognostic (1.98e-1)" "unprognostic (2.49e-2)" "unprognostic (2.72e-2)" 98.7 2.9 16.2 5.7 17.9 22.6 67.7 18.3 26.9 8.7 10.4 21.0 21.2 2.9 0.8 20.9 4.3 3.0 2.8 15.7 18.8 3.6 194.7 25.5 9.1 27.4 22.4 1.3 9.7 26.8 2.6 16.0 21.3 8.8 11.5 0.6 9.8 3.4 19.1 118.7 20.8 2.5 25.7 7.7 12.5 1.0 24.5 4.1 6.5 4.5 6.3 8.7 14.8 34.8 2.5 5.1 0.1 7.1 55.8 0.0 196.9 0.1 1.5 0.1 0.0 24.8 0.1 0.0 3.0 0.0 1.1 9.4 5.8 0.6 0.0 35.8 7.2 0.1 0.1 110.9 0.9 36.6 42.1 2.2 25.4 0.0 0.2 0.0 0.0 2.8 2.4 0.0 0.0 12.7 0.2 114.1 5.0 61.8 2.7 0.0 0.4 1.1 0.2 17.7 0.4 1.7 0.7 0.5 0.8 6.2 13.7 407.7 0.1 0.1 0.8 0.1 0.9 0.4 0.0 0.2 0.0 130.9 0.0 16.0 7.1 0.0 0.8 12.3 0.7 0.0 0.1 0.5 5.1 0.1 0.2 0.4 2.5 0.0 15.7 0.2 0.0 2.1 16.2 17.9 18.3 26.9 15.7 18.8 27.4 22.4 21.3 25.7 24.5 34.8 5.4 16.0 37.8 0.0 2.8 37.3 20.8 3.3 22.2 0.7 6.2 12.2 0.4 57.2 5.1 0.0 0.0 40.3 14.4 91.6 3.9 0.5 0.0 0.8 0.8 4.9 4.2 5.7 1.9 5.8 44.3 9.5 12.8 1.3 1.3 0.0 2.2 106.5 87.0 0.0 0.3 24.8 4.1 35.0 27.4 0.2 3.1 42.9 5.4 17.8 28.2 8.4 6.2 1.0 0.4 1.9 30.6 1.5 2.0 15.1 42.5 4.9 5.1 0.5 0.0 4.1 3.1 0.2 0.7 29.7 171.8 212.3 5.0 0.3 51.5 12.2 CEBPZ "CBF2, CTF2" ENSG00000115816 "CCAAT enhancer binding protein zeta" Q03701 2 37201612-37231596 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 282.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052065 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles Nucleoplasm "HPA052065: AB_2681715" "unprognostic (1.64e-2)" "unprognostic (1.20e-1)" "unprognostic (3.00e-3)" "prognostic unfavorable (5.07e-4)" "unprognostic (2.88e-1)" "unprognostic (1.72e-2)" "prognostic unfavorable (2.94e-5)" "unprognostic (8.84e-2)" "unprognostic (3.85e-3)" "unprognostic (2.66e-1)" "prognostic unfavorable (8.13e-4)" "unprognostic (2.65e-2)" "unprognostic (5.36e-2)" "unprognostic (4.19e-2)" "unprognostic (8.76e-2)" "unprognostic (2.05e-1)" "unprognostic (8.01e-2)" 21.1 27.8 10.3 18.9 11.5 31.3 26.2 15.8 12.8 17.9 11.9 19.5 17.4 20.1 19.9 20.5 17.2 16.7 15.3 9.8 11.8 25.3 27.1 19.3 24.6 10.9 11.0 23.9 20.6 22.3 10.2 23.0 11.4 19.7 20.0 24.4 16.3 15.6 36.3 17.9 18.1 16.9 10.8 19.9 17.4 38.4 11.1 24.0 22.4 24.4 24.4 26.6 12.6 14.2 61.2 46.6 46.9 26.1 45.2 48.6 39.9 57.0 39.2 47.2 50.5 74.5 45.1 111.5 49.4 33.8 64.4 51.0 122.8 58.5 60.2 71.8 53.9 104.0 47.5 60.9 35.8 105.7 44.9 37.3 56.4 62.8 63.4 31.1 43.3 27.8 114.8 49.8 48.6 31.8 61.5 82.4 153.3 81.0 43.2 48.6 76.3 84.3 45.3 56.9 49.9 80.7 47.5 57.6 65.5 67.6 41.8 45.9 35.5 45.8 52.3 41.3 79.1 55.5 62.0 88.1 40.8 95.6 51.2 34.8 16.8 16.3 23.8 21.7 30.0 29.6 24.7 23.4 17.6 30.0 31.1 26.1 6.1 26.1 22.3 25.6 21.4 14.6 10.3 11.5 15.8 12.8 9.8 11.8 10.9 11.0 11.4 10.8 11.1 14.2 73.4 86.6 82.9 15.0 91.6 107.1 109.2 64.4 83.1 45.5 50.4 54.1 34.4 47.1 81.9 49.7 43.8 54.7 93.4 36.7 107.6 56.1 282.1 56.0 87.2 60.5 44.2 66.7 15.6 62.5 37.4 67.4 52.5 67.5 73.4 44.7 43.9 76.4 35.1 43.7 19.3 56.6 44.7 37.0 36.1 43.3 60.9 44.6 21.4 15.0 54.1 57.1 63.8 18.6 21.4 54.9 30.2 50.8 67.7 79.0 30.2 89.1 54.2 95.5 52.6 94.3 68.3 186.7 99.3 56.8 101.2 45.0 87.7 62.1 64.2 80.9 CECR2 KIAA1740 ENSG00000099954 "CECR2 histone acetyl-lysine reader" Q9BXF3 22 17359949-17558149 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.5;retina: 15.6;skeletal muscle: 21.8" "Cell type enhanced" "Detected in many" "Astrocytes: 109.4;Cone photoreceptor cells: 168.9;Oligodendrocyte precursor cells: 120.1;Oligodendrocytes: 137.7;Rod photoreceptor cells: 94.1" "Cancer enriched" "Detected in many" 6 "testis cancer: 8.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 15.5;HAP1: 14.4;K-562: 8.3;NTERA-2: 22.8;SCLC-21H: 10.1;SuSa: 9.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA002943 Approved Approved Nucleoplasm,Vesicles No No "Cluster 54: Non-specific - Microtubule organization" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Vesicles "HPA002943: AB_1078496" "unprognostic (2.46e-2)" "unprognostic (4.10e-2)" "unprognostic (7.99e-2)" "unprognostic (1.92e-3)" "unprognostic (7.48e-3)" "unprognostic (2.46e-3)" "unprognostic (2.49e-1)" "unprognostic (6.67e-2)" "unprognostic (8.18e-2)" "unprognostic (3.94e-1)" "unprognostic (5.36e-2)" "unprognostic (1.25e-1)" "unprognostic (8.13e-6)" "unprognostic (1.13e-1)" "unprognostic (1.59e-1)" "unprognostic (6.56e-2)" "unprognostic (1.94e-2)" 0.7 0.4 5.2 0.2 12.8 0.5 1.0 22.5 8.3 1.4 1.2 1.2 0.2 2.3 0.6 0.4 1.7 0.2 3.4 5.3 8.0 1.3 7.6 2.6 0.1 9.8 9.0 2.9 2.6 0.0 6.4 1.0 8.7 1.0 0.3 15.6 0.9 0.2 21.8 0.9 0.5 0.9 5.4 0.4 0.5 3.5 9.8 0.2 2.2 10.6 0.2 1.3 1.0 12.7 0.2 0.1 15.5 5.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.6 0.0 0.7 0.1 14.4 0.0 0.0 0.0 7.2 0.0 0.1 0.0 0.4 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.5 8.3 0.0 0.0 0.1 0.0 0.5 22.8 0.0 0.0 1.8 1.0 0.1 0.0 5.1 10.1 0.0 0.0 0.2 0.9 9.0 1.6 2.5 0.1 0.1 3.4 0.0 0.0 5.8 1.4 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 12.8 22.5 8.3 5.3 8.0 9.8 9.0 8.7 5.4 9.8 12.7 1.9 6.4 10.6 109.4 0.3 0.0 1.1 0.2 0.0 22.1 0.7 0.6 11.8 0.0 0.8 1.8 168.9 10.1 0.0 0.0 0.0 0.1 6.3 6.3 6.2 2.0 0.0 0.0 2.3 0.2 2.5 3.1 0.0 17.2 0.0 3.5 4.2 10.7 0.7 5.0 4.3 0.0 0.0 0.3 0.3 4.0 1.2 1.4 0.0 34.7 0.2 18.3 0.0 120.1 137.7 0.1 0.0 1.2 0.8 1.8 0.0 1.4 0.9 94.1 6.6 33.9 3.2 1.9 15.9 0.1 0.1 33.0 0.2 0.4 0.0 3.6 CELF2 "BRUNOL3, CUGBP2, Etr-3, NAPOR-2" ENSG00000048740 "CUGBP Elav-like family member 2" O95319 10 10798397-11336675 "Predicted intracellular proteins" "mRNA processing" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.9" "Cell type enhanced" "Detected in many" "Astrocytes: 558.0;Excitatory neurons: 1676.4;Inhibitory neurons: 576.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 200.2;HMC-1: 186.2;REH: 86.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016395, HPA035813" Enhanced Supported "Nucleoplasm,Vesicles,Midbody ring" Yes No "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Vesicles, Midbody ring" "CAB016395: AB_2086271, HPA035813: AB_2674797" "unprognostic (1.62e-2)" "unprognostic (1.52e-2)" "unprognostic (1.90e-2)" "unprognostic (3.55e-2)" "unprognostic (9.00e-2)" "prognostic favorable (7.61e-4)" "unprognostic (1.57e-1)" "unprognostic (3.77e-2)" "unprognostic (4.20e-2)" "unprognostic (5.22e-2)" "unprognostic (2.60e-3)" "unprognostic (2.83e-2)" "unprognostic (2.14e-1)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "unprognostic (2.31e-2)" "unprognostic (1.45e-1)" 39.6 5.7 33.7 30.7 42.7 78.9 17.7 0.2 42.0 14.2 0.0 16.5 9.2 15.0 5.0 21.4 13.3 17.2 37.5 42.5 7.2 3.0 4.3 28.2 42.4 0.9 13.9 46.8 4.4 3.5 6.5 8.6 0.4 14.1 17.9 35.4 9.6 12.2 17.6 8.6 23.4 23.2 8.6 31.1 10.3 7.6 23.7 60.7 8.5 15.0 29.4 16.2 8.0 21.0 0.1 0.0 47.6 0.0 7.4 2.7 5.3 7.0 0.2 1.1 0.2 0.1 0.0 0.1 5.3 6.1 0.0 0.1 6.8 0.2 0.4 40.4 11.9 200.2 0.7 0.0 1.7 58.0 186.2 3.0 0.3 0.4 0.0 0.7 6.7 70.6 9.3 80.7 59.6 0.0 71.9 42.0 19.3 0.0 0.0 86.7 50.8 18.0 3.4 0.0 7.1 0.5 0.1 0.2 51.1 15.2 0.0 39.0 0.1 8.9 2.5 29.9 0.1 30.7 30.1 9.3 2.9 68.8 21.6 68.0 43.2 90.8 54.8 57.5 69.2 48.1 54.1 60.5 53.4 51.0 56.1 52.7 115.1 73.5 67.8 37.9 60.9 63.5 33.7 42.7 0.2 42.0 42.5 7.2 0.9 13.9 0.4 8.6 23.7 21.0 20.4 160.3 147.3 558.0 165.6 19.9 3.4 5.8 12.5 68.2 18.8 13.7 122.7 5.7 22.4 12.9 102.2 1.1 233.5 11.8 15.6 1.6 135.9 5.3 11.3 34.7 59.3 45.2 1676.4 2.1 0.9 106.0 11.2 17.0 128.5 0.7 13.2 5.1 90.0 134.6 576.9 37.5 24.4 261.4 134.3 110.3 111.6 192.9 115.6 376.6 263.6 90.5 256.4 324.7 21.6 1.5 16.9 89.5 124.3 10.1 2.4 1.0 5.8 99.2 52.6 117.6 33.7 4.1 11.5 5.7 14.5 1.9 232.5 8.5 23.8 2.4 CEMIP2 TMEM2 ENSG00000135048 "Cell migration inducing hyaluronidase 2" Q9UHN6 9 71683366-71816690 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Developmental protein, Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 92.5;placenta: 79.6" "Cell type enhanced" "Detected in some" "Adipocytes: 105.8;dendritic cells: 378.1;Glandular and luminal cells: 137.3;Plasma cells: 155.1;Syncytiotrophoblasts: 89.8;T-cells: 86.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 143.4;BEWO: 117.4;OE19: 144.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017080, HPA044889" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA 150000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 21: OE19 - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Vesicles, Cytosol" "HPA017080: , HPA044889: AB_10962641" "unprognostic (2.06e-1)" "unprognostic (1.12e-1)" "unprognostic (3.85e-2)" "unprognostic (1.01e-2)" "unprognostic (6.15e-3)" "unprognostic (1.21e-2)" "unprognostic (2.93e-2)" "unprognostic (3.53e-1)" "unprognostic (3.29e-2)" "unprognostic (1.92e-1)" "unprognostic (1.57e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.13e-2)" "unprognostic (2.33e-1)" "unprognostic (7.59e-2)" "unprognostic (1.16e-1)" 25.1 5.4 9.7 24.8 6.5 29.7 11.1 9.7 8.3 5.1 15.0 24.2 27.2 7.2 2.7 6.6 5.6 41.5 7.7 19.0 2.8 10.4 60.2 35.0 23.1 4.1 3.6 2.2 19.3 92.5 4.6 79.6 4.9 7.0 28.0 17.3 11.1 8.0 4.8 6.1 23.7 11.7 4.1 15.9 33.2 6.8 8.2 18.6 9.4 8.6 20.7 32.0 3.4 5.5 22.5 85.0 143.4 6.6 13.7 22.9 117.4 81.7 48.7 51.6 40.5 24.3 31.3 0.4 20.0 18.8 11.6 35.2 38.6 9.9 73.2 2.5 11.2 38.9 20.9 68.7 23.9 0.4 9.8 28.0 11.4 38.9 8.1 14.0 68.2 3.3 4.7 10.2 28.8 15.1 4.1 0.6 28.2 144.3 8.6 3.3 39.9 2.4 31.6 60.4 6.3 0.6 19.3 12.5 20.5 45.2 8.8 1.3 30.3 33.7 38.3 17.4 39.3 1.8 37.8 0.9 6.1 3.9 43.7 0.1 1.3 3.1 1.4 1.1 0.3 0.4 1.5 1.3 0.5 3.0 2.1 1.0 2.3 0.3 1.0 0.1 2.3 0.9 9.7 6.5 9.7 8.3 19.0 2.8 4.1 3.6 4.9 4.1 8.2 5.5 105.8 0.0 0.0 0.0 47.6 0.0 0.0 0.0 0.0 0.0 58.7 46.7 0.0 0.0 0.0 14.7 0.0 47.9 378.1 0.0 0.0 20.2 0.0 42.1 24.2 14.7 0.0 0.0 0.0 36.2 14.4 4.3 0.0 137.3 0.0 3.8 0.0 0.0 46.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 30.8 0.0 0.0 155.1 0.0 0.0 11.6 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.0 89.8 86.1 3.1 0.0 0.0 CEP295NL "DDC8, KIAA1731NL" ENSG00000178404 "CEP295 N-terminal like" Q96MC4 17 78870910-78903217 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "brain: 9.2;testis: 33.6" "Group enriched" "Detected in some" 133 "Early spermatids: 298.6;Late spermatids: 504.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.4;Karpas-707: 1.1;TIME: 1.2;U-2 OS: 1.9" "Not detected" "Not detected" "HPA023609, HPA024619, HPA025717" Uncertain Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA023609: AB_10610974, HPA024619: AB_10602076, HPA025717: AB_10601900" "unprognostic (1.68e-3)" "unprognostic (4.56e-2)" "unprognostic (2.62e-1)" "unprognostic (5.04e-3)" "unprognostic (1.88e-1)" "unprognostic (1.59e-1)" "unprognostic (1.89e-1)" "unprognostic (9.03e-2)" "unprognostic (8.16e-2)" "unprognostic (9.80e-2)" "unprognostic (2.08e-1)" "unprognostic (3.89e-3)" "unprognostic (3.65e-3)" "unprognostic (1.03e-1)" "unprognostic (2.09e-1)" "unprognostic (1.28e-1)" "unprognostic (6.75e-3)" 0.1 0.1 1.9 0.0 2.2 1.3 0.1 0.5 2.8 0.4 1.6 0.1 0.0 0.2 0.0 0.5 0.2 0.0 0.1 0.9 1.8 0.0 0.0 0.1 0.0 2.8 1.9 0.3 0.1 0.0 0.1 0.1 3.4 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 1.0 0.3 0.1 33.6 3.3 0.0 0.0 0.0 0.0 0.1 0.3 9.2 0.3 0.0 0.0 0.3 0.1 0.2 1.4 0.6 0.0 0.2 0.3 0.1 0.2 0.0 0.4 0.2 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.3 0.3 0.0 0.4 1.2 0.5 1.9 0.6 0.2 0.4 0.6 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 1.9 2.2 0.5 2.8 0.9 1.8 2.8 1.9 3.4 1.0 3.3 9.2 0.7 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 298.6 0.3 1.7 0.5 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.8 0.0 0.5 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 504.5 2.8 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 1.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 3.0 1.4 0.1 0.0 0.0 0.1 0.7 0.0 0.1 CERK "dA59H18.2, dA59H18.3, DKFZp434E0211, FLJ21430, FLJ23239, hCERK, KIAA1646, LK4" ENSG00000100422 "Ceramide kinase" Q8TCT0 22 46684410-46738252 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064699 Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 12: NES - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" Vesicles "HPA064699: AB_2685327" "unprognostic (2.93e-2)" "unprognostic (1.93e-1)" "unprognostic (6.52e-2)" "prognostic unfavorable (4.75e-4)" "unprognostic (2.67e-2)" "unprognostic (1.49e-3)" "unprognostic (8.55e-2)" "unprognostic (3.60e-2)" "unprognostic (3.87e-1)" "unprognostic (1.35e-2)" "prognostic favorable (2.35e-4)" "unprognostic (2.26e-1)" "unprognostic (1.50e-3)" "unprognostic (1.27e-1)" "unprognostic (4.78e-1)" "unprognostic (3.38e-1)" "prognostic unfavorable (1.58e-4)" 15.7 23.7 17.5 22.2 18.1 21.1 12.7 33.2 22.5 17.8 16.4 17.9 31.6 17.5 6.0 14.8 18.2 17.4 39.0 18.3 37.4 19.5 18.9 16.6 26.1 32.1 34.5 26.6 30.2 11.5 49.0 10.0 33.2 11.7 14.9 21.1 17.5 13.4 20.8 16.3 31.2 15.2 20.8 19.4 21.9 6.0 26.2 38.7 21.0 19.2 25.2 13.7 12.4 18.4 25.6 15.1 71.6 22.6 40.3 30.2 6.7 43.7 33.8 24.5 17.2 22.3 8.4 35.3 19.9 46.9 15.1 16.3 30.4 19.8 24.9 12.6 33.0 15.8 36.9 29.0 27.9 49.9 4.0 25.3 25.0 26.7 9.1 39.2 73.5 37.1 12.1 44.5 45.4 1.9 34.0 24.8 32.4 10.3 16.3 62.8 81.2 40.4 14.7 0.5 66.4 60.6 21.5 10.3 47.1 16.5 11.3 37.6 67.4 50.2 26.8 37.5 64.4 45.7 59.5 22.3 53.5 28.0 41.7 0.7 3.0 3.7 10.3 7.0 17.9 2.0 10.7 10.0 5.4 2.1 6.3 5.8 4.2 2.6 8.7 5.7 10.4 4.4 17.5 18.1 33.2 22.5 18.3 37.4 32.1 34.5 33.2 20.8 26.2 18.4 28.6 9.6 16.6 16.0 17.0 3.4 6.3 6.1 18.2 24.4 6.1 9.8 44.2 10.0 11.0 1.8 6.2 2.4 25.4 23.4 15.6 12.8 7.8 10.3 19.8 27.4 14.4 8.0 11.7 11.8 1.4 14.1 9.2 19.8 10.1 10.2 25.4 22.1 10.8 26.9 21.9 6.6 8.2 24.8 16.9 16.0 9.6 22.1 3.6 15.9 18.6 25.6 22.6 9.5 4.2 10.9 15.2 15.1 43.3 2.1 50.0 16.8 0.7 9.7 0.0 8.3 13.2 4.7 1.7 11.0 4.4 1.8 37.6 5.3 20.0 1.7 CERS4 "FLJ12089, LASS4, Trh1" ENSG00000090661 "Ceramide synthase 4" Q9HA82 19 8206736-8262421 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 71.3;Muller glia cells: 150.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 55.1;NB-4: 99.8;U-937: 61.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033734, HPA054729" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Vesicles" "CAB033734: AB_2132977, HPA054729: " "unprognostic (5.96e-2)" "prognostic favorable (2.71e-4)" "unprognostic (2.46e-2)" "unprognostic (2.82e-2)" "unprognostic (1.30e-1)" "prognostic favorable (7.83e-4)" "unprognostic (1.74e-1)" "prognostic favorable (3.45e-5)" "unprognostic (1.48e-2)" "unprognostic (3.32e-1)" "prognostic favorable (8.05e-4)" "unprognostic (1.77e-1)" "prognostic favorable (9.63e-5)" "unprognostic (6.08e-3)" "unprognostic (2.69e-2)" "unprognostic (2.91e-2)" "unprognostic (8.08e-3)" 13.6 13.0 31.8 10.0 38.9 3.4 31.1 26.6 37.1 35.9 18.7 17.7 6.3 21.5 61.5 64.3 21.3 11.2 14.8 35.3 25.2 27.8 57.7 19.4 19.9 36.9 30.5 22.0 89.1 29.0 22.2 1.9 30.8 32.9 3.9 36.9 55.0 17.6 3.1 47.7 15.2 12.0 26.8 17.7 26.8 11.5 30.7 13.1 51.9 5.3 20.4 18.4 32.7 44.0 0.4 2.1 2.1 25.0 0.8 0.2 1.7 3.1 8.4 3.7 1.7 19.5 1.7 40.0 27.4 0.0 9.6 13.6 16.4 0.4 1.7 35.5 12.4 7.6 0.1 55.1 31.6 0.0 21.3 12.3 20.7 8.8 18.9 10.5 0.3 17.7 5.9 1.2 0.0 0.8 2.6 99.8 25.4 0.2 8.7 49.1 0.8 3.0 6.3 0.0 9.3 12.2 4.3 0.7 14.5 16.7 18.8 8.8 0.2 2.9 7.8 18.6 0.1 24.5 21.1 32.0 0.1 61.9 2.8 12.3 7.1 27.4 7.5 3.9 5.7 19.8 4.3 4.6 4.1 17.7 3.9 3.8 22.4 22.4 2.4 3.9 5.5 5.8 31.8 38.9 26.6 37.1 35.3 25.2 36.9 30.5 30.8 26.8 30.7 44.0 3.2 6.4 10.7 27.1 31.2 18.0 13.2 12.0 15.4 24.5 47.0 28.8 4.1 22.8 22.2 1.8 18.8 3.4 17.2 0.2 7.9 20.0 1.7 7.9 11.2 8.6 23.9 4.0 38.3 30.5 0.9 15.7 3.1 7.6 12.7 14.4 8.2 71.3 16.4 11.8 24.4 1.3 8.2 7.1 7.2 7.3 14.3 6.7 26.6 16.9 19.6 150.3 27.8 47.7 48.1 9.4 2.5 16.1 12.4 40.6 0.4 44.6 27.8 29.5 6.6 6.9 13.8 1.0 1.6 20.6 25.9 2.9 15.7 2.7 2.5 11.9 CFAP410 "A2, C21orf2, LRRC76, YF5" ENSG00000160226 "Cilia and flagella associated protein 410" O43822 21 44328944-44339402 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, DNA damage" "Ciliopathy, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 30.8;Extravillous trophoblasts: 15.7;Hofbauer cells: 35.5;Syncytiotrophoblasts: 32.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030283, HPA030284, CAB034126, CAB034128" Supported Supported Vesicles,Mitochondria,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "Vesicles, Cytosol" "CAB034126: AB_1564257, CAB034128: AB_1564259, HPA030283: , HPA030284: AB_10602700" "unprognostic (1.84e-1)" "unprognostic (1.56e-1)" "unprognostic (3.14e-2)" "unprognostic (1.29e-2)" "unprognostic (2.11e-3)" "unprognostic (1.36e-1)" "unprognostic (6.58e-2)" "unprognostic (1.13e-2)" "unprognostic (9.73e-2)" "unprognostic (2.77e-1)" "prognostic favorable (1.32e-4)" "unprognostic (1.49e-1)" "prognostic favorable (4.08e-4)" "unprognostic (2.98e-1)" "unprognostic (2.79e-1)" "unprognostic (1.32e-2)" "unprognostic (1.06e-1)" 19.8 22.2 14.5 5.1 14.6 11.4 19.5 13.8 18.6 22.9 12.7 21.1 6.5 23.4 2.3 12.5 26.3 3.8 19.9 14.9 14.5 26.0 26.8 18.5 6.6 16.5 16.8 22.3 24.0 7.5 34.4 3.3 14.5 26.3 1.4 10.0 18.6 5.0 16.1 17.9 19.2 2.4 13.9 20.9 20.7 30.9 18.5 4.2 32.8 4.9 2.3 19.2 14.8 16.2 12.9 5.2 4.9 6.3 3.2 2.0 19.3 6.4 3.7 2.5 1.3 9.4 3.7 9.1 12.5 2.2 5.1 6.0 0.9 1.2 0.6 14.2 12.9 9.5 4.3 11.2 4.1 10.2 9.8 2.9 2.2 1.0 2.2 4.4 1.6 6.7 11.6 15.1 1.6 15.5 11.2 25.0 12.2 6.4 7.8 28.6 6.3 20.3 2.9 18.0 12.9 12.2 8.9 2.1 11.0 2.9 9.3 22.0 7.5 5.4 6.9 5.8 4.9 25.1 14.2 6.4 13.2 20.4 9.9 1.7 10.2 1.6 9.4 12.6 11.3 16.6 10.0 13.2 10.5 11.6 11.3 11.1 1.3 17.3 9.5 31.3 6.1 7.6 14.5 14.6 13.8 18.6 14.9 14.5 16.5 16.8 14.5 13.9 18.5 16.2 5.5 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 30.8 6.9 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 15.7 7.4 0.0 0.0 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 32.7 1.1 0.0 0.0 0.0 CFAP58 "bA554P13.1, C10orf80, CCDC147, FLJ35908" ENSG00000120051 "Cilia and flagella associated protein 58" Q5T655 10 104353833-104455102 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 8.4;testis: 13.4" "Group enriched" "Detected in some" 4 "Early spermatids: 73.3;Endometrial ciliated cells: 25.1;Late spermatids: 58.9;Respiratory ciliated cells: 56.9;Spermatocytes: 34.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 2.1" "Lineage enriched" "Detected in single" 21 "granulocytes: 2.1" "Cell line enhanced" "Detected in some" "BJ hTERT+: 3.1;U-2 OS: 6.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.9" "HPA036555, HPA071938" Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 9: U-2 OS - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "Plasma membrane, Cytosol" "HPA036555: AB_10673622, HPA071938: " "unprognostic (5.32e-1)" "unprognostic (2.59e-1)" "unprognostic (6.26e-2)" "unprognostic (1.57e-3)" "unprognostic (5.41e-3)" "unprognostic (1.01e-1)" "unprognostic (9.62e-2)" "unprognostic (5.64e-2)" "unprognostic (3.11e-1)" "unprognostic (2.18e-1)" "unprognostic (8.93e-2)" "unprognostic (3.15e-1)" "unprognostic (1.65e-1)" "unprognostic (3.97e-2)" "unprognostic (6.81e-2)" "unprognostic (4.19e-2)" "unprognostic (1.59e-1)" 0.4 0.6 1.0 0.5 1.3 0.4 0.4 0.4 0.7 2.2 2.4 0.5 0.1 1.8 0.2 0.2 8.4 0.2 2.5 0.8 1.2 0.7 0.1 1.3 0.3 2.9 3.7 0.5 0.3 0.7 1.5 0.4 2.2 0.5 0.0 0.6 0.2 0.4 1.3 0.3 0.2 0.6 2.0 0.3 0.3 13.4 1.0 0.1 0.8 0.8 0.4 0.3 0.6 1.1 0.1 0.0 0.7 0.1 0.1 0.3 0.1 1.0 3.1 0.6 1.6 0.0 0.0 2.4 0.2 0.4 1.7 0.2 0.0 0.2 1.8 0.3 0.1 0.5 0.9 0.0 0.3 0.3 0.4 0.3 1.3 0.5 1.6 1.3 1.0 0.1 0.7 0.7 0.8 0.0 0.0 0.7 0.2 0.0 0.0 0.2 0.2 0.3 0.3 0.0 0.4 0.2 0.0 0.1 0.5 0.7 0.1 0.4 2.0 0.6 6.5 0.3 1.8 0.2 0.0 0.1 0.7 0.8 2.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 1.0 1.3 0.4 0.7 0.8 1.2 2.9 3.7 2.2 2.0 1.0 1.1 0.4 0.0 0.5 1.6 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 10.0 0.0 9.3 0.0 0.0 0.1 0.1 0.0 0.0 0.6 73.3 25.1 0.3 0.4 0.0 0.0 4.0 0.2 0.4 0.7 0.0 0.4 0.0 0.3 1.8 0.0 0.1 0.0 2.1 0.1 0.0 0.0 0.0 58.9 0.6 0.2 0.0 1.9 0.1 0.7 1.0 1.0 0.0 0.3 0.0 1.2 0.0 0.2 0.0 0.0 56.9 0.3 0.0 0.8 1.0 34.4 4.0 0.0 0.0 0.1 0.0 0.6 0.0 0.2 CFAP73 "CCDC42B, MIA2" ENSG00000186710 "Cilia and flagella associated protein 73" A6NFT4 12 113149858-113159276 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 21.6;choroid plexus: 28.1;fallopian tube: 42.2" "Cell type enriched" "Detected in some" 4 "Endometrial ciliated cells: 110.3" "Cancer enhanced" "Detected in many" "endometrial cancer: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 4.3;REH: 2.2;T-47d: 2.5;U-698: 9.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA048539 Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoli fibrillar center" "Nucleoplasm, Vesicles" "HPA048539: AB_2680434" "unprognostic (2.42e-2)" "prognostic favorable (1.29e-4)" "unprognostic (1.90e-3)" "prognostic favorable (5.52e-4)" "unprognostic (2.32e-2)" "unprognostic (1.18e-3)" "unprognostic (6.49e-2)" "unprognostic (2.94e-1)" "unprognostic (1.33e-1)" "unprognostic (3.14e-1)" "unprognostic (5.68e-2)" "unprognostic (3.43e-2)" "unprognostic (1.62e-4)" "unprognostic (2.03e-4)" "unprognostic (1.60e-1)" "unprognostic (4.03e-2)" "unprognostic (1.55e-2)" 0.2 0.4 3.2 0.4 2.8 2.1 0.3 1.1 1.0 3.8 28.1 0.3 0.3 0.5 0.3 0.5 42.2 0.2 0.2 5.5 5.8 1.7 0.5 7.1 0.7 17.9 21.6 0.4 0.4 0.1 1.2 0.0 11.3 0.6 0.0 0.2 2.3 0.7 0.3 4.7 0.5 0.0 15.0 0.6 4.0 0.5 4.6 0.0 0.8 0.0 1.2 0.2 0.2 3.4 0.2 0.0 0.2 0.3 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.3 2.0 4.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.3 0.2 1.7 0.1 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.3 0.0 0.0 0.7 0.2 0.7 0.3 0.8 0.1 2.2 0.0 0.3 0.5 0.5 0.4 0.1 0.0 0.6 0.0 0.2 2.5 0.0 0.1 0.1 0.7 0.2 0.1 0.4 0.1 9.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.8 1.1 1.0 5.5 5.8 17.9 21.6 11.3 15.0 4.6 3.4 0.0 0.0 1.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.0 0.0 6.2 3.7 0.0 0.1 0.1 0.2 0.0 0.0 0.4 110.3 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.6 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.3 0.3 0.0 0.0 0.0 0.8 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.2 0.1 23.3 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.1 0.1 0.2 CFAP94 "CASC1, FLJ10921, LAS1, PPP1R54" ENSG00000118307 "Cilia and flagella associated protein 94" Q6TDU7 12 25108289-25195162 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 12.4;fallopian tube: 14.0;testis: 22.9" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 1.9;Fibroblasts: 1.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "T-47d: 1.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039662, HPA040141" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 24: Non-specific - Transcription regulation" Cytosol Vesicles "HPA039662: AB_10795468, HPA040141: " "unprognostic (6.42e-3)" "unprognostic (1.26e-2)" "unprognostic (1.95e-2)" "unprognostic (2.04e-3)" "unprognostic (4.62e-1)" "unprognostic (1.85e-2)" "unprognostic (1.55e-1)" "unprognostic (3.53e-2)" "unprognostic (2.22e-1)" "unprognostic (3.91e-2)" "unprognostic (6.21e-4)" "unprognostic (2.54e-2)" "prognostic favorable (3.13e-4)" "unprognostic (2.01e-1)" "unprognostic (8.74e-3)" "unprognostic (7.16e-2)" "unprognostic (1.19e-1)" 0.2 0.7 1.6 0.2 2.3 0.6 1.5 0.9 2.0 2.0 12.4 0.3 0.0 1.6 6.0 0.5 14.0 0.7 0.4 2.1 2.3 2.7 0.0 1.9 0.4 5.7 6.0 1.2 0.7 3.3 4.0 0.1 4.2 1.0 0.0 5.1 0.7 1.1 0.1 1.0 0.1 0.3 4.0 0.2 0.6 22.9 3.0 0.4 4.1 0.0 0.1 0.2 0.2 2.5 0.1 0.3 0.4 0.3 0.2 0.2 0.2 0.0 0.3 0.2 0.3 0.0 1.0 1.1 0.3 0.0 0.1 0.2 0.0 0.2 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.2 0.0 0.4 0.0 1.1 0.6 0.4 0.0 0.0 0.2 0.5 0.2 0.1 0.0 0.4 0.1 0.0 1.0 0.1 0.6 0.2 0.1 0.0 0.1 0.5 1.3 0.0 0.0 0.1 0.8 0.5 0.1 0.4 0.2 0.9 0.3 0.2 0.2 0.2 0.1 0.3 0.1 0.1 0.1 0.6 0.0 0.2 0.0 0.9 0.1 0.2 1.3 0.3 0.2 0.3 0.0 0.1 1.6 2.3 0.9 2.0 2.1 2.3 5.7 6.0 4.2 4.0 3.0 2.5 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 CFB "BF, BFD, H2-Bf" ENSG00000243649 "Complement factor B" P00751 6 31945650-31952084 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "liver: 2613.2" "Cell type enhanced" "Detected in many" "Ductal cells: 873.6;Exocrine glandular cells: 197.3;Hepatocytes: 284.0;Pancreatic endocrine cells: 318.0;Proximal enterocytes: 139.7" "Cancer enhanced" "Detected in all" "liver cancer: 78.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 15.0;ASC TERT1: 23.0;EFO-21: 25.1;fHDF/TERT166: 14.1;HSkMC: 19.1;U-87 MG: 10.1" "Low region specificity" "Detected in all" "HPA000951, HPA001817, HPA001832, CAB016381" Supported Approved "Endoplasmic reticulum,Vesicles,Cell Junctions" "Secreted to blood" NA NA 879000000 120000000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Endoplasmic reticulum, Vesicles" "Cell Junctions" "CAB016381: AB_627562, HPA000951: AB_2797216, HPA001817: AB_1078779, HPA001832: AB_1078778" "prognostic favorable (2.76e-5)" "unprognostic (1.02e-1)" "unprognostic (1.44e-1)" "unprognostic (7.94e-2)" "unprognostic (1.82e-2)" "unprognostic (8.56e-2)" "unprognostic (8.08e-3)" "unprognostic (8.81e-2)" "unprognostic (3.51e-1)" "unprognostic (2.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.57e-2)" "prognostic unfavorable (1.53e-5)" "unprognostic (1.36e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-2)" "unprognostic (3.68e-2)" 143.7 18.0 3.6 32.8 3.6 0.1 28.5 3.4 9.9 16.3 3.9 22.3 28.1 8.2 14.2 24.1 53.7 0.8 42.6 3.7 3.4 58.7 2613.2 39.2 4.2 4.1 3.7 9.9 51.8 0.2 17.7 5.0 3.8 60.3 14.5 1.4 43.3 0.0 3.0 7.7 73.1 48.3 3.4 12.9 54.5 2.1 3.7 1.9 15.5 0.7 6.7 17.8 9.2 3.6 0.5 1.9 0.1 0.0 15.0 23.0 0.1 0.0 0.2 1.1 0.0 0.1 8.6 0.1 25.1 14.1 0.6 6.0 0.0 1.8 1.2 1.0 0.3 0.7 0.4 0.5 0.0 1.0 0.4 19.1 0.4 0.6 0.5 1.3 0.2 0.1 0.3 0.7 0.1 0.2 0.1 0.3 0.4 0.0 0.4 0.3 0.3 1.3 1.7 0.5 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.2 0.0 3.4 1.2 0.4 0.4 0.7 2.1 1.0 10.1 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.6 3.6 3.4 9.9 3.7 3.4 4.1 3.7 3.8 3.4 3.7 3.6 1.0 0.0 16.9 0.0 2.6 0.8 0.9 64.8 11.4 0.3 4.9 0.9 0.4 44.3 127.3 5.5 0.0 0.1 0.0 3.7 3.9 873.6 0.0 1.9 0.4 3.9 2.4 16.0 0.2 197.3 0.2 34.6 20.9 1.2 0.0 0.0 11.7 284.0 1.0 0.0 0.2 8.5 18.3 19.7 1.0 0.0 2.8 1.1 0.0 5.6 18.1 0.4 0.0 0.0 0.0 318.0 10.6 0.0 0.1 8.6 139.7 17.1 75.4 0.7 0.0 1.0 12.6 0.1 0.1 3.9 1.8 1.6 1.6 0.0 12.4 4.5 CFDP1 "BCNT, CENP-29, CP27, p97, SWC5, Yeti" ENSG00000153774 "Craniofacial development protein 1" Q9UEE9 16 75293698-75433503 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 493.3;Paneth cells: 745.2;Proximal enterocytes: 612.2;Proximal tubular cells: 637.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041316, HPA048242" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA041316: AB_10794371, HPA048242: AB_2680327" "unprognostic (1.45e-1)" "unprognostic (8.64e-2)" "unprognostic (1.13e-1)" "unprognostic (4.88e-1)" "unprognostic (3.97e-2)" "prognostic unfavorable (9.63e-5)" "unprognostic (5.81e-3)" "unprognostic (2.17e-1)" "unprognostic (1.26e-2)" "unprognostic (2.61e-2)" "unprognostic (1.42e-1)" "unprognostic (7.37e-2)" "unprognostic (2.85e-2)" "unprognostic (6.54e-2)" "unprognostic (1.36e-1)" "unprognostic (4.92e-3)" "unprognostic (1.25e-1)" 45.0 51.0 57.4 24.0 58.0 35.0 45.2 60.8 75.3 69.1 57.9 47.5 30.4 58.6 62.3 41.2 55.6 29.7 36.8 57.1 61.7 64.5 43.1 37.3 27.1 58.8 59.3 83.1 41.2 30.8 57.1 63.1 58.8 39.9 40.2 49.6 39.4 38.1 35.7 42.4 36.4 51.0 56.7 30.2 34.7 59.5 59.6 57.0 45.0 34.9 35.8 44.8 50.7 60.8 65.0 47.6 158.9 59.2 141.2 156.3 47.2 63.2 74.1 83.0 119.1 82.5 86.6 61.3 91.1 79.3 92.7 71.5 123.3 101.9 164.9 26.4 58.6 63.0 46.6 177.2 97.3 69.2 51.6 98.4 85.5 100.2 121.4 144.6 91.5 114.0 91.3 28.3 93.9 149.0 102.2 152.6 77.1 110.0 24.8 182.7 64.3 108.5 93.1 35.5 94.5 79.4 105.7 22.3 92.5 136.4 91.8 121.6 53.8 59.2 63.1 63.2 40.8 54.4 89.2 228.6 59.3 89.9 53.3 61.3 45.5 60.8 31.2 47.8 44.5 33.6 42.7 34.7 48.8 35.4 38.7 36.5 38.1 28.5 46.2 48.7 68.5 25.8 57.4 58.0 60.8 75.3 57.1 61.7 58.8 59.3 58.8 56.7 59.6 60.8 87.4 38.5 57.5 37.5 45.5 57.9 116.3 135.9 47.3 87.2 89.5 103.4 34.7 91.5 111.2 115.8 116.7 119.0 50.5 493.3 197.6 79.1 133.7 197.7 118.5 97.6 82.2 78.9 49.5 94.9 114.0 82.9 61.2 121.3 28.5 194.5 62.8 153.9 77.1 62.2 50.5 219.2 59.0 53.1 44.5 69.7 125.2 51.1 33.8 45.9 64.8 60.8 84.5 49.8 75.6 92.4 745.2 112.5 42.3 116.9 612.2 637.6 205.3 112.5 98.6 55.3 88.2 311.2 178.0 49.5 65.6 154.9 51.6 103.5 120.0 130.4 CFH "ARMD4, ARMS1, FHL1, HF, HF1, HF2, HUS" ENSG00000000971 "Complement factor H" P08603 1 196652043-196747504 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement alternate pathway, Host-virus interaction, Immunity, Innate immunity" "Age-related macular degeneration, Cancer-related genes, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 1676.3" "Group enriched" "Detected in many" 4 "Fibroblasts: 448.0;Hepatocytes: 1114.8;Leydig cells: 283.9" "Cancer enriched" "Detected in all" 9 "liver cancer: 151.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 18.7" "Lineage enriched" "Detected in single" 26 "T-cells: 18.7" "Cell line enhanced" "Detected in many" "HHSteC: 123.1;HSkMC: 119.5;hTERT-RPE1: 374.9;RT4: 227.0" "CAB016385, CAB016769, HPA038922, HPA049176, HPA053326" Supported Approved Vesicles "Secreted to blood" NA NA 396000000000 100000000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB016385: AB_627572, CAB016769: , HPA038922: AB_2676271, HPA049176: AB_2680663, HPA053326: AB_2682113" "unprognostic (2.40e-1)" "unprognostic (9.86e-2)" "unprognostic (1.22e-1)" "unprognostic (8.39e-2)" "unprognostic (5.40e-3)" "unprognostic (1.80e-1)" "unprognostic (3.75e-3)" "unprognostic (7.40e-2)" "unprognostic (1.06e-1)" "unprognostic (1.04e-1)" "unprognostic (9.08e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.92e-6)" "unprognostic (6.50e-3)" "unprognostic (4.49e-3)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" 125.3 42.1 18.1 32.7 21.5 1.3 66.9 20.0 29.6 76.8 43.0 51.0 30.5 12.8 15.9 63.8 24.2 133.6 301.5 18.1 18.6 25.5 1676.3 70.8 27.4 19.3 19.0 165.1 14.0 6.4 16.0 26.1 19.9 23.0 80.2 4.3 126.7 24.0 21.1 74.5 52.1 32.5 19.5 13.9 46.9 14.3 21.6 12.1 102.5 84.0 25.9 149.9 27.0 21.1 0.0 64.9 0.0 0.0 96.5 54.7 0.1 25.8 63.1 3.5 13.5 0.1 11.9 0.3 9.6 0.1 0.2 2.2 0.0 23.6 2.6 1.3 0.0 20.0 74.7 0.0 123.1 0.9 0.3 119.5 0.3 18.4 7.9 374.9 79.2 0.0 74.4 2.7 89.4 0.1 0.5 0.1 0.4 0.0 0.1 0.2 89.8 21.0 0.0 227.0 0.0 0.1 0.4 0.0 0.1 0.6 0.1 0.0 5.6 73.6 0.9 0.8 0.8 0.8 0.0 0.3 13.1 0.2 5.8 0.0 0.1 0.0 2.0 0.0 18.7 0.0 6.6 4.0 0.2 0.0 0.4 1.5 0.7 0.0 0.0 0.0 0.0 1.1 18.1 21.5 20.0 29.6 18.1 18.6 19.3 19.0 19.9 19.5 21.6 21.1 73.9 9.6 17.6 0.7 4.2 44.2 63.6 140.6 14.2 2.4 1.3 3.4 10.9 35.8 141.1 5.5 0.0 0.0 3.1 0.1 0.0 6.2 2.6 2.3 3.8 49.8 0.0 52.6 0.6 0.8 0.0 448.0 8.6 1.9 3.8 6.9 47.8 1114.8 1.1 0.0 1.0 0.0 14.2 43.8 62.1 7.4 283.9 5.7 44.4 38.4 0.3 0.3 0.0 0.0 0.2 5.3 0.0 138.8 2.6 13.0 0.0 0.5 115.6 1.4 6.6 94.2 59.6 1.4 1.0 10.9 38.2 0.1 13.2 26.3 0.0 61.5 CFHR1 "CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, H36-1, H36-2, HFL1, HFL2" ENSG00000244414 "Complement factor H related 1" Q03591 1 196819731-196832189 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 272 "liver: 2081.3" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 320.0" "Cancer enriched" "Detected in single" 798 "liver cancer: 182.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.0;HeLa: 1.2;HL-60: 2.0;U-266/70: 2.4" "Not detected" "Not detected" "HPA038915, HPA038922, HPA040726" Supported Approved Vesicles "Secreted to blood" NA NA 13000000000 "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA038915: AB_2676269, HPA038922: AB_2676271, HPA040726: AB_2677101" "unprognostic (2.28e-1)" "unprognostic (3.18e-1)" "unprognostic (3.50e-2)" "unprognostic (1.88e-2)" "prognostic favorable (8.71e-6)" "unprognostic (3.02e-1)" "unprognostic (3.70e-1)" "unprognostic (2.50e-1)" "unprognostic (8.48e-2)" "unprognostic (7.21e-4)" "unprognostic (7.01e-4)" "unprognostic (1.13e-1)" "unprognostic (6.41e-2)" 1.5 0.6 0.1 1.8 0.1 0.0 0.5 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.2 7.6 2081.3 0.1 6.7 0.1 0.8 0.3 0.3 0.0 0.1 0.1 0.4 0.2 0.2 0.2 0.1 0.0 0.2 0.1 0.7 0.2 0.1 6.1 0.2 0.1 0.2 0.0 0.1 0.2 0.0 0.4 0.2 0.1 0.0 0.0 0.1 0.1 1.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 2.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.1 0.9 0.3 0.0 0.6 0.0 0.3 0.0 0.0 0.3 0.8 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.5 0.3 0.1 0.1 0.0 2.4 0.0 0.4 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.8 0.4 0.1 0.2 0.1 0.5 3.2 0.0 0.0 2.2 0.4 0.1 0.0 0.0 1.2 0.0 0.1 1.8 11.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 18.7 0.0 0.0 0.0 9.9 0.0 0.0 0.0 6.0 15.0 320.0 5.6 0.0 0.4 0.0 0.0 16.9 0.4 0.2 1.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.0 41.0 2.1 0.3 1.5 0.0 0.0 0.3 1.4 5.6 0.1 0.1 CFP PFC ENSG00000126759 "Complement factor properdin" P27918 X 47623172-47630305 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 83.9;lymphoid tissue: 58.4" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 108.1;Kupffer cells: 356.7;Langerhans cells: 164.1;Macrophages: 177.3;monocytes: 473.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in all" 8 "classical monocyte: 1167.5;intermediate monocyte: 1273.6;myeloid DC: 994.5;neutrophil: 730.3;non-classical monocyte: 868.9" "Group enriched" "Detected in all" 46 "dendritic cells: 994.5;granulocytes: 730.3;monocytes: 1273.6" "Cell line enhanced" "Detected in some" "EFO-21: 20.7;HEL: 5.0;HMC-1: 5.5;NB-4: 10.7;U-937: 7.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA072644 Approved Vesicles "Secreted to blood" NA NA 6200000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 38: EFO-21 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA072644: " "unprognostic (2.77e-3)" "unprognostic (2.21e-3)" "unprognostic (1.00e-1)" "unprognostic (2.15e-2)" "unprognostic (4.15e-2)" "unprognostic (9.66e-5)" "unprognostic (9.90e-3)" "unprognostic (1.30e-2)" "unprognostic (5.37e-2)" "unprognostic (1.20e-1)" "unprognostic (1.08e-2)" "unprognostic (2.70e-1)" "unprognostic (1.97e-2)" "unprognostic (2.58e-1)" "unprognostic (1.32e-1)" "unprognostic (4.62e-2)" "unprognostic (2.17e-1)" 6.0 1.9 0.3 20.5 0.3 83.9 2.1 0.3 0.6 0.6 0.2 2.1 1.2 0.9 0.2 1.6 3.4 2.1 2.6 0.4 0.1 0.8 12.0 9.3 11.7 0.1 0.0 0.7 0.8 0.1 0.8 0.9 0.0 0.7 0.9 0.2 1.0 0.2 1.0 1.5 3.7 5.2 0.0 58.4 1.5 0.6 0.0 5.1 0.9 0.7 4.4 4.9 0.7 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 20.7 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.2 5.0 0.2 0.0 0.1 1.1 5.5 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 0.2 0.0 10.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.2 1.0 0.0 0.1 0.5 0.1 0.4 0.4 0.1 0.1 7.2 0.0 131.5 1167.5 39.9 3.0 1273.6 2.3 6.7 15.1 1.8 994.5 2.6 21.8 8.1 730.3 12.3 868.9 30.9 14.1 1071.9 0.3 0.3 0.3 0.6 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 9.1 1.0 5.8 4.0 0.1 0.3 1.2 3.4 0.7 0.4 0.9 1.5 2.8 0.0 0.0 0.3 1.7 0.3 0.0 0.2 0.2 0.4 0.4 7.4 0.0 2.5 1.4 0.7 0.5 2.0 1.1 0.6 1.3 4.0 108.1 2.0 17.3 1.7 1.1 0.0 0.0 356.7 164.1 0.3 0.9 177.3 5.4 0.0 473.7 0.3 4.1 2.0 0.3 0.3 0.1 1.2 1.2 0.3 0.1 0.5 7.5 1.9 0.0 1.5 1.2 0.0 0.2 0.5 3.0 0.4 4.8 3.1 0.6 0.0 CGRRF1 "CGR19, RNF197" ENSG00000100532 "Cell growth regulator with ring finger domain 1" Q99675 14 54509812-54539292 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 145.4;Spermatocytes: 112.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002930 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Vesicles "HPA002930: AB_1078507" "unprognostic (1.81e-1)" "unprognostic (3.76e-1)" "unprognostic (5.61e-2)" "unprognostic (4.38e-1)" "unprognostic (1.01e-1)" "unprognostic (3.21e-1)" "prognostic unfavorable (6.84e-4)" "unprognostic (2.25e-1)" "unprognostic (5.58e-2)" "unprognostic (2.63e-1)" "unprognostic (7.29e-2)" "unprognostic (2.64e-3)" "prognostic favorable (2.57e-8)" "unprognostic (2.94e-1)" "unprognostic (1.61e-1)" "unprognostic (1.48e-1)" "unprognostic (1.74e-1)" 9.9 9.2 20.5 3.9 21.1 7.9 11.9 22.2 25.8 9.6 21.2 11.7 5.3 11.0 13.8 5.9 11.2 5.9 12.3 20.2 21.2 14.5 7.8 7.5 6.0 21.2 21.4 10.0 13.1 12.8 12.7 7.0 21.2 11.3 6.9 13.6 8.5 10.9 19.3 4.2 8.5 8.6 22.1 8.5 9.7 22.3 20.9 5.6 12.7 12.5 5.3 10.1 7.5 22.3 10.4 8.6 9.7 8.6 16.7 10.6 7.3 9.5 10.2 14.6 15.2 8.7 11.7 5.9 11.9 8.2 15.8 9.1 10.8 8.4 18.5 11.9 8.7 8.3 1.7 10.6 20.1 4.6 4.4 10.9 16.7 11.0 18.1 9.6 10.6 9.3 3.3 7.6 13.6 19.0 4.9 7.2 6.0 9.5 15.3 10.8 12.3 2.9 11.8 13.3 6.4 6.3 8.3 3.9 16.1 8.7 11.3 4.2 9.3 18.2 14.3 7.2 8.7 5.0 6.4 8.5 10.0 5.6 12.0 61.9 12.4 22.6 19.1 15.4 18.7 18.2 19.9 20.2 10.4 19.4 20.0 18.6 12.5 20.3 19.0 9.0 22.3 19.7 20.5 21.1 22.2 25.8 20.2 21.2 21.2 21.4 21.2 22.1 20.9 22.3 20.3 9.6 11.5 21.5 22.6 7.6 17.4 26.7 16.5 18.6 18.3 18.7 22.1 14.3 17.3 16.5 10.4 14.7 21.8 17.5 23.5 21.6 145.4 13.7 15.1 20.3 10.7 4.2 14.2 16.9 11.5 22.3 5.6 13.1 29.2 12.7 18.9 10.6 17.0 11.8 13.8 9.1 28.5 14.8 10.3 41.5 16.8 24.8 16.0 12.2 15.5 29.4 16.5 17.1 24.3 17.7 13.1 22.6 11.5 16.8 15.6 27.3 22.6 15.9 19.7 17.0 25.0 112.2 36.0 10.0 3.4 12.0 24.0 12.3 11.0 14.0 CHEK1 CHK1 ENSG00000149554 "Checkpoint kinase 1" O14757 11 125625665-125676255 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.7;lymphoid tissue: 20.7;seminal vesicle: 29.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 32.9;Erythroid cells: 34.5;Extravillous trophoblasts: 35.6;Spermatocytes: 48.9;Spermatogonia: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "T-reg: 6.2" "Group enriched" "Detected in many" 5 "granulocytes: 1.7;T-cells: 6.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA044364 Supported Nucleoplasm,Vesicles NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Vesicles "HPA044364: AB_2678913" "unprognostic (6.74e-2)" "unprognostic (3.63e-1)" "prognostic favorable (3.62e-4)" "unprognostic (5.54e-2)" "unprognostic (2.17e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.70e-6)" "unprognostic (3.95e-3)" "unprognostic (1.26e-3)" "unprognostic (2.54e-2)" "prognostic unfavorable (3.10e-6)" "unprognostic (1.75e-1)" "prognostic unfavorable (1.04e-8)" "unprognostic (2.89e-2)" "unprognostic (2.64e-1)" "unprognostic (8.16e-2)" "unprognostic (1.33e-1)" 1.6 1.3 0.7 8.2 1.0 25.7 2.6 0.6 1.3 1.7 0.5 7.9 6.8 1.7 6.7 4.1 1.1 1.7 0.9 0.7 0.9 2.2 2.1 1.3 14.9 0.7 0.8 1.8 2.0 13.2 1.7 4.8 0.8 1.6 8.7 0.7 1.5 29.8 0.6 3.6 7.3 3.4 0.6 2.2 2.6 8.9 1.2 20.7 1.0 1.3 13.9 3.3 2.1 0.8 48.5 37.0 81.1 47.4 13.5 28.9 35.7 61.1 28.7 41.6 40.1 88.0 100.3 120.7 63.5 24.9 53.7 52.6 54.2 33.2 50.1 81.4 24.8 224.2 27.2 44.7 4.3 121.1 39.6 15.7 6.0 47.6 36.0 19.9 44.7 84.1 117.3 102.7 51.4 23.8 181.3 65.0 86.1 77.1 33.2 104.7 74.4 67.2 37.9 63.2 50.5 53.6 45.2 35.4 15.2 57.3 93.9 40.6 28.4 51.0 47.3 29.6 60.8 21.9 45.4 187.5 20.5 86.6 67.6 1.7 0.2 0.0 0.4 0.1 0.2 0.7 1.6 0.4 0.6 0.3 0.4 0.3 1.1 0.3 0.1 0.7 6.2 0.4 0.7 1.0 0.6 1.3 0.7 0.9 0.7 0.8 0.8 0.6 1.2 0.8 1.1 3.2 0.5 1.6 5.5 6.2 3.9 5.8 5.2 1.7 3.9 6.0 4.6 32.9 4.1 7.3 0.0 17.3 6.0 4.5 3.9 3.4 7.8 5.5 8.0 3.5 1.8 34.5 3.3 1.1 35.6 5.3 6.1 9.9 0.0 21.1 3.6 1.2 11.1 0.0 2.5 9.2 2.0 0.0 5.2 3.1 1.5 3.2 0.0 2.8 3.2 2.8 3.1 1.5 1.6 2.9 3.9 1.2 17.7 3.1 8.0 9.4 2.5 1.7 0.0 3.1 7.8 48.9 49.8 9.5 4.8 7.8 5.1 4.8 16.7 3.0 CHGA ENSG00000100604 "Chromogranin A" P10645 14 92923150-92935285 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins" "Antibiotic, Antimicrobial, Fungicide" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "parathyroid gland: 6568.4" "Cell type enriched" "Detected in many" 7 "Enteroendocrine cells: 6553.1" "Cancer enhanced" "Detected in many" "pancreatic cancer: 114.8" "Group enriched" "Detected in many" 16 "cerebral cortex: 326.0;white matter: 124.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 151 "SCLC-21H: 489.5;SH-SY5Y: 1339.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000023, HPA017369, CAB040544, CAB055506, CAB058688" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 295000000 100000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "CAB000023: , CAB040544: , CAB055506: AB_2081135, CAB058688: AB_2665574, HPA017369: AB_1846698" "prognostic favorable (7.85e-5)" "unprognostic (4.89e-2)" "unprognostic (5.96e-2)" "unprognostic (1.17e-1)" "unprognostic (1.43e-2)" "unprognostic (5.95e-2)" "prognostic unfavorable (2.40e-4)" "unprognostic (1.74e-1)" "unprognostic (2.23e-1)" "unprognostic (4.56e-2)" "prognostic favorable (4.07e-4)" "unprognostic (1.85e-1)" "unprognostic (8.81e-13)" "unprognostic (1.07e-2)" "unprognostic (1.77e-1)" "unprognostic (9.17e-2)" "prognostic unfavorable (3.99e-4)" 14.5 1248.5 8.6 9.4 11.4 0.2 0.3 0.0 326.0 8.3 0.0 92.0 242.7 0.4 0.3 1.0 1.1 0.2 0.2 4.4 1.7 1.0 0.4 1.6 0.1 14.4 0.0 0.2 102.5 6568.4 446.2 0.0 4.1 12.2 105.2 11.0 0.2 0.3 0.1 0.6 179.9 0.9 0.0 0.1 364.5 77.7 4.3 0.6 24.6 0.0 0.0 1.3 1.2 124.4 0.0 0.5 2.4 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.8 2.7 0.0 0.0 0.2 0.0 1.4 0.0 0.0 489.5 1339.4 0.0 0.4 0.1 0.0 0.1 0.1 0.0 0.0 4.2 0.3 0.4 0.0 0.0 0.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 11.4 0.0 326.0 4.4 1.7 14.4 0.0 4.1 0.0 4.3 124.4 0.1 0.0 0.0 11.1 1.0 0.9 0.4 0.0 0.0 17.3 0.2 0.3 2.9 0.0 0.0 0.0 29.2 0.3 0.0 9.8 0.0 0.1 1.3 6.0 2.3 0.8 6553.1 0.0 59.5 0.4 0.1 4.1 195.7 0.5 0.0 0.5 0.0 0.0 1.5 16.8 37.7 820.4 14.2 0.0 0.0 7.9 39.7 0.1 7.2 15.9 2.0 3.7 0.0 10.6 12.8 46.5 137.8 137.3 0.0 6.6 36.7 0.0 0.0 16.2 0.0 0.0 0.2 4.7 2.2 0.0 0.0 0.3 0.2 0.4 25.9 5.1 CHGB "SCG1, SgI" ENSG00000089199 "Chromogranin B" P05060 20 5911510-5925353 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "adrenal gland: 3466.0;pituitary gland: 1425.3" "Cell type enriched" "Detected in many" 5 "Enteroendocrine cells: 1036.1" "Cancer enriched" "Detected in many" 6 "pancreatic cancer: 154.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "SCLC-21H: 355.0;SH-SY5Y: 541.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008759, CAB009403, HPA012602" Enhanced Supported Enhanced Vesicles "Intracellular and membrane" NA NA 6500000 "Cluster 20: T-cells - T-cell receptor" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "CAB009403: AB_2081255, HPA008759: AB_1846704, HPA012602: AB_1846706" "unprognostic (1.79e-3)" "unprognostic (7.72e-2)" "unprognostic (3.48e-1)" "unprognostic (2.90e-2)" "unprognostic (1.68e-2)" "prognostic unfavorable (1.89e-4)" "unprognostic (7.96e-3)" "unprognostic (2.86e-1)" "unprognostic (6.18e-3)" "unprognostic (7.93e-2)" "prognostic favorable (9.96e-4)" "unprognostic (8.56e-2)" "unprognostic (8.21e-2)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "unprognostic (2.73e-1)" "unprognostic (1.01e-2)" 27.5 3466.0 17.1 5.3 9.9 0.8 2.1 134.2 90.9 0.6 0.0 7.9 60.2 1.6 4.2 0.6 13.7 0.4 71.9 101.9 92.2 8.3 0.7 2.4 3.1 76.5 100.2 25.8 92.8 6.4 1425.3 0.7 188.4 5.3 14.2 56.9 6.1 3.8 11.0 1.7 31.6 0.9 12.8 0.3 133.3 14.9 19.3 4.0 9.7 0.8 1.4 0.4 2.3 14.2 0.0 7.9 0.9 0.0 0.2 0.2 0.4 0.2 0.0 0.1 0.0 1.9 0.0 0.0 4.3 0.0 4.9 0.1 0.0 0.1 0.1 0.6 0.1 2.6 0.0 1.6 0.1 4.2 0.2 1.5 0.0 0.0 2.1 0.1 0.1 0.2 0.4 0.1 1.0 0.0 0.1 0.9 19.7 1.3 0.0 0.1 0.0 0.4 0.5 0.2 355.0 541.8 0.0 0.5 0.4 2.1 0.3 0.4 0.3 0.1 6.4 0.4 3.3 0.0 0.7 2.7 0.5 3.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 17.1 9.9 134.2 90.9 101.9 92.2 76.5 100.2 188.4 12.8 19.3 14.2 0.0 3.2 2.4 7.5 0.3 4.2 9.9 0.8 0.0 93.3 0.1 0.3 114.4 0.0 0.7 69.9 20.9 0.1 0.0 1.6 1.9 0.5 7.1 0.2 0.7 3.0 1036.1 0.0 31.6 0.4 0.0 18.9 4.1 0.3 0.0 202.8 0.0 0.3 0.1 75.7 28.8 61.9 65.1 0.3 9.5 8.3 0.9 1.6 7.2 9.4 1.1 13.7 1.0 7.5 5.2 22.9 17.7 0.4 0.0 3.3 3.2 0.3 4.4 75.6 13.1 3.0 1.6 76.6 41.8 0.0 3.7 0.3 1.0 3.0 2.2 4.2 CHI3L1 "GP39, YK-40, YKL40" ENSG00000133048 "Chitinase 3 like 1" P36222 1 203178931-203186704 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Inflammatory response" Antimicrobial "Asthma, Cancer-related genes, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 232.4;brain: 239.4;liver: 447.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 88.7;Ductal cells: 88.9;Hepatocytes: 61.8;Hofbauer cells: 317.5" "Cancer enriched" "Detected in all" 8 "glioma: 1313.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 495 "neutrophil: 470.4" "Lineage enriched" "Detected in single" 495 "granulocytes: 470.4" "Cell line enhanced" "Detected in some" "ASC diff: 322.9;ASC TERT1: 712.9;HSkMC: 637.0;THP-1: 1068.4;U-138 MG: 303.5;U-87 MG: 303.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in some" 10 "olfactory bulb: 16.0" HPA077365 Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 25100000 180000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus" Vesicles "HPA077365: " "unprognostic (2.11e-3)" "unprognostic (1.21e-1)" "unprognostic (1.29e-1)" "unprognostic (1.07e-1)" "unprognostic (6.01e-3)" "unprognostic (8.81e-2)" "unprognostic (2.09e-1)" "unprognostic (1.48e-1)" "unprognostic (4.46e-2)" "unprognostic (1.30e-1)" "unprognostic (7.98e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (1.98e-2)" "unprognostic (3.43e-2)" "unprognostic (1.14e-2)" "unprognostic (9.39e-3)" 79.8 2.0 58.9 138.9 75.9 232.4 62.8 55.3 94.7 30.5 56.8 6.5 0.4 19.5 1.0 14.4 23.4 3.0 9.8 47.4 129.6 60.9 447.8 38.4 32.4 239.4 112.8 6.6 13.8 0.2 134.5 10.1 135.6 13.7 2.0 50.9 99.4 0.9 21.0 75.6 16.8 6.8 70.0 13.9 9.7 1.0 156.4 12.4 15.0 1.0 36.9 97.8 9.1 70.8 0.8 0.0 0.0 0.3 322.9 712.9 0.0 0.0 0.2 0.0 0.0 75.3 0.2 0.1 1.2 0.4 0.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 8.3 0.3 0.3 637.0 0.0 1.9 0.3 30.8 0.0 0.0 0.0 1.0 0.2 0.3 0.0 5.8 2.7 0.0 0.0 0.0 0.1 15.4 0.0 0.0 0.0 0.0 0.3 0.5 0.4 0.2 0.0 1068.4 0.0 303.5 1.6 0.0 0.4 2.3 41.9 0.3 303.7 1.2 0.2 0.0 0.4 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 470.4 0.0 0.9 0.0 0.0 1.3 58.9 75.9 55.3 94.7 47.4 129.6 239.4 112.8 135.6 70.0 156.4 70.8 0.7 6.4 42.8 20.5 0.1 4.2 47.1 88.7 0.0 0.1 29.8 21.5 1.0 2.8 17.3 27.6 0.0 1.3 0.6 0.0 0.0 88.9 0.0 4.8 2.2 2.1 0.0 0.4 1.1 0.0 1.1 18.6 0.0 7.2 0.0 0.0 0.0 61.8 317.5 0.0 0.1 0.0 6.1 0.8 0.4 0.0 0.9 23.7 14.2 0.0 1.0 45.1 0.0 0.0 0.1 2.0 0.0 0.0 1.4 4.2 0.0 0.2 3.4 2.8 0.0 1.0 2.3 0.0 0.0 1.5 1.1 0.8 0.9 0.0 0.0 2.2 CHIC1 BRX ENSG00000204116 "Cysteine rich hydrophobic domain 1" Q5VXU3 X 73563200-73687102 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 47.0;Excitatory neurons: 62.7;Inhibitory neurons: 59.6;Microglial cells: 29.0;Oligodendrocyte precursor cells: 66.9;Oligodendrocytes: 76.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 20.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026782, HPA052062" Uncertain Approved "Nuclear speckles,Vesicles,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear speckles, Vesicles" Cytosol "HPA026782: AB_1846654, HPA052062: AB_2681714" "unprognostic (9.85e-3)" "unprognostic (3.91e-2)" "unprognostic (3.10e-2)" "unprognostic (9.95e-2)" "unprognostic (6.22e-2)" "unprognostic (1.91e-1)" "unprognostic (1.57e-1)" "unprognostic (1.36e-2)" "unprognostic (2.43e-1)" "unprognostic (1.25e-1)" "unprognostic (4.42e-3)" "unprognostic (2.65e-1)" "prognostic favorable (2.75e-4)" "unprognostic (1.37e-2)" "unprognostic (2.19e-1)" "unprognostic (3.51e-1)" "unprognostic (2.76e-2)" 2.9 7.0 4.4 3.0 4.8 0.6 3.7 4.6 8.5 7.1 2.4 5.2 2.3 5.6 3.8 2.4 4.2 4.6 5.4 5.7 6.1 6.3 1.5 2.7 3.9 5.9 4.6 5.7 2.2 5.9 5.6 2.1 6.0 4.8 4.2 5.4 2.8 5.1 2.6 3.0 3.4 5.4 4.9 4.1 2.5 1.5 5.8 2.8 6.5 5.2 3.5 4.2 3.4 5.1 4.6 4.7 2.3 3.0 6.5 8.7 0.0 5.1 6.8 4.1 4.9 3.1 5.8 2.1 6.9 4.6 8.1 1.4 3.3 2.5 9.0 5.3 4.1 3.2 4.0 0.0 4.2 0.0 6.0 6.1 2.9 7.7 4.1 5.2 5.9 2.1 0.8 20.3 8.1 0.7 1.9 0.0 7.3 0.0 4.6 1.8 5.9 1.3 5.1 2.3 1.3 1.9 5.8 2.7 6.3 3.9 2.3 1.3 6.9 4.7 4.6 9.4 3.1 5.7 15.3 0.0 6.9 3.4 3.7 0.2 0.0 0.0 0.4 0.0 0.7 0.2 0.3 0.4 0.0 0.2 0.3 0.4 0.0 0.3 0.0 0.0 0.3 0.1 4.4 4.8 4.6 8.5 5.7 6.1 5.9 4.6 6.0 4.9 5.8 5.1 8.3 3.2 9.1 47.0 9.4 2.7 4.6 2.7 4.6 10.0 4.2 3.6 12.7 5.7 4.1 3.7 6.2 0.2 7.5 2.1 0.0 3.5 4.1 10.9 5.6 9.4 0.0 4.4 62.7 3.5 0.0 8.2 1.5 7.3 5.1 5.3 5.3 1.6 1.6 13.5 59.6 7.5 2.0 2.2 1.8 1.8 3.1 2.3 5.4 29.0 1.6 5.7 8.2 66.9 76.1 2.4 6.1 9.1 6.7 5.4 1.4 11.4 3.9 7.5 0.0 8.3 5.0 2.0 2.4 2.4 4.5 0.0 8.8 5.9 3.4 4.6 CHIC2 BTL ENSG00000109220 "Cysteine rich hydrophobic domain 2" Q9UKJ5 4 54009789-54064605 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 348.7;Suprabasal keratinocytes: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "granulocytes: 365.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026782, HPA026784, HPA076603" Uncertain Enhanced "Vesicles,Plasma membrane" NA Yes "Cluster 38: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Vesicles, Plasma membrane" "HPA026782: AB_1846654, HPA026784: AB_2732433, HPA076603: AB_2732317" "unprognostic (4.56e-2)" "unprognostic (2.24e-3)" "unprognostic (3.47e-3)" "unprognostic (9.58e-2)" "unprognostic (1.49e-1)" "unprognostic (2.25e-2)" "unprognostic (7.87e-2)" "unprognostic (1.22e-1)" "unprognostic (3.65e-2)" "unprognostic (7.81e-3)" "unprognostic (2.94e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (1.56e-4)" "unprognostic (2.89e-1)" "unprognostic (1.77e-1)" "unprognostic (4.56e-2)" "unprognostic (9.40e-2)" 20.8 15.9 9.1 12.9 8.5 27.1 18.1 12.6 9.6 16.0 12.1 12.4 12.3 12.3 10.3 27.4 12.1 20.5 15.1 8.6 9.2 14.2 20.3 19.7 14.7 8.6 8.5 13.0 9.9 6.5 9.3 13.5 9.0 12.9 8.9 5.9 15.2 5.7 9.8 27.5 13.2 10.5 7.8 17.3 12.9 39.6 9.2 21.9 11.9 6.6 13.3 15.1 18.1 9.7 25.4 4.6 12.8 11.9 21.5 16.8 13.1 34.6 36.1 20.1 20.3 18.1 22.0 21.4 29.5 22.0 17.2 7.7 17.9 25.1 22.0 11.9 9.5 11.7 4.2 13.6 65.1 19.2 23.4 22.6 19.8 30.3 45.3 38.3 30.0 22.2 13.0 15.4 40.6 7.1 22.3 30.7 8.7 11.2 16.9 14.3 7.3 8.4 23.3 8.1 19.7 18.3 8.3 12.2 26.6 18.3 6.1 26.8 51.3 25.2 19.9 36.6 21.4 18.4 9.5 17.2 18.7 18.7 18.7 365.5 79.3 171.5 60.1 64.7 57.7 41.3 60.0 68.6 55.9 40.1 54.6 59.6 325.0 74.2 68.3 47.0 81.5 77.9 9.1 8.5 12.6 9.6 8.6 9.2 8.6 8.5 9.0 7.8 9.2 9.7 58.1 6.4 7.3 35.6 42.5 348.7 95.5 61.0 68.3 8.1 61.6 33.5 4.1 15.7 25.9 7.3 8.4 27.8 57.8 27.2 17.6 42.8 55.4 64.1 58.0 64.3 25.8 72.6 39.7 28.0 38.7 80.8 32.6 34.2 36.3 36.8 38.6 23.9 24.7 13.5 40.2 21.9 40.7 36.4 144.2 13.4 17.1 50.3 67.6 49.6 32.6 9.0 28.8 74.4 23.2 61.8 42.1 24.5 40.2 85.1 41.9 29.2 56.0 7.2 19.7 53.9 45.1 163.5 89.9 97.4 373.8 47.7 65.8 39.8 21.0 135.9 CHP1 "CHP, p22, p24, Sid470p, SLC9A1BP" ENSG00000187446 "Calcineurin like EF-hand protein 1" Q99653 15 41230839-41281887 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Protein kinase inhibitor" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 434.4;Distal tubular cells: 389.4;Hepatocytes: 353.6;Proximal enterocytes: 425.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006616 Approved Approved Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA006616: AB_1857461" "unprognostic (2.06e-2)" "unprognostic (3.26e-1)" "unprognostic (2.84e-1)" "prognostic favorable (9.63e-4)" "unprognostic (7.29e-2)" "unprognostic (3.74e-1)" "prognostic favorable (4.07e-6)" "unprognostic (2.20e-1)" "unprognostic (7.46e-2)" "unprognostic (3.26e-2)" "unprognostic (1.26e-3)" "unprognostic (2.79e-1)" "prognostic favorable (2.79e-6)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (4.62e-3)" "unprognostic (2.04e-1)" 66.9 55.3 22.1 28.0 24.4 58.4 32.8 26.0 26.5 34.0 24.7 113.8 85.4 21.8 34.1 74.5 20.8 48.1 53.2 30.3 32.9 76.1 185.1 52.7 18.6 32.9 31.0 19.1 42.2 54.1 21.6 26.3 35.8 34.3 81.9 20.5 49.9 27.5 81.0 45.5 70.0 27.6 26.9 20.2 112.7 10.7 33.3 20.1 49.8 86.5 41.1 44.8 41.3 28.4 72.4 72.7 28.3 109.0 120.4 113.8 41.0 56.2 69.1 44.8 48.0 66.6 140.4 12.6 59.8 77.7 47.7 89.0 56.0 83.9 51.5 44.8 20.0 50.8 58.1 103.6 93.5 66.5 73.7 116.7 98.8 51.9 53.3 68.0 82.1 37.9 81.2 79.5 52.5 43.5 27.7 72.5 29.0 118.4 35.9 35.9 46.2 34.0 92.5 144.1 17.4 44.3 96.4 178.2 48.7 49.9 101.0 66.3 108.3 47.5 50.3 76.9 36.7 45.0 131.6 59.4 84.9 42.2 44.1 255.5 227.6 274.8 49.5 204.4 51.5 40.2 46.2 50.0 152.1 33.0 29.1 41.4 173.3 56.5 207.4 95.1 60.7 116.5 22.1 24.4 26.0 26.5 30.3 32.9 32.9 31.0 35.8 26.9 33.3 28.4 28.3 44.8 117.3 20.9 26.8 72.3 62.4 48.1 20.5 11.0 101.6 39.2 80.5 243.1 50.7 103.0 10.4 33.3 38.3 434.4 389.4 96.7 52.5 68.0 48.8 39.5 55.6 58.5 24.8 150.6 62.4 38.2 112.7 114.4 37.4 18.9 78.1 353.6 68.5 11.8 21.0 136.2 34.6 170.1 134.8 122.6 29.5 77.1 129.9 19.7 113.4 32.7 36.0 9.5 23.6 173.9 206.4 29.3 24.0 80.1 425.0 231.1 33.7 10.3 26.3 46.6 41.4 13.7 19.3 50.6 108.5 66.9 32.9 65.7 161.4 130.8 CHPF "CHSY2, CSS2" ENSG00000123989 "Chondroitin polymerizing factor" Q8IZ52 2 219538948-219543809 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 163.7;Extravillous trophoblasts: 182.7;Syncytiotrophoblasts: 310.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 9.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035123 Approved Supported Vesicles,Centrosome,Cytosol "Intracellular and membrane" NA NA 570000 "Cluster 52: Eosinophils - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Vesicles, Centrosome" "HPA035123: AB_10602799" "unprognostic (1.13e-3)" "prognostic unfavorable (1.57e-4)" "unprognostic (3.65e-3)" "unprognostic (2.55e-3)" "unprognostic (1.86e-3)" "prognostic unfavorable (1.68e-4)" "unprognostic (1.37e-1)" "unprognostic (6.59e-3)" "unprognostic (7.74e-2)" "unprognostic (1.19e-2)" "unprognostic (1.18e-1)" "unprognostic (6.79e-2)" "unprognostic (1.64e-1)" "unprognostic (6.55e-2)" "unprognostic (1.82e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (2.96e-4)" 29.9 45.7 26.9 12.5 24.9 1.7 22.3 25.8 34.2 59.1 36.7 21.9 26.7 55.9 13.7 27.3 30.2 24.2 134.8 38.4 31.2 41.1 97.8 42.8 6.5 34.0 30.4 127.4 138.9 24.6 128.3 40.6 32.1 58.6 4.7 8.5 56.1 25.6 16.3 26.2 23.2 12.6 27.4 16.6 40.9 97.5 33.2 3.6 52.8 3.9 4.5 34.3 30.0 34.0 67.5 13.0 9.6 81.0 36.0 55.8 109.7 66.4 55.4 18.5 16.8 36.8 57.5 20.7 139.0 64.6 63.3 84.1 6.3 40.3 2.9 32.3 22.5 7.4 18.0 161.9 49.8 6.6 42.1 75.0 69.2 18.8 17.9 66.7 0.1 7.1 47.2 49.6 17.7 105.5 1.0 17.6 39.8 22.8 50.6 0.1 30.4 41.6 22.4 29.7 23.4 36.0 32.1 30.7 94.3 17.9 10.5 22.6 1.6 67.9 37.1 81.9 35.2 58.9 19.9 9.7 62.1 6.7 70.4 1.7 0.0 6.5 1.9 0.1 2.4 1.0 1.5 1.3 0.0 0.1 1.7 0.6 0.0 1.9 0.0 9.5 1.2 0.7 26.9 24.9 25.8 34.2 38.4 31.2 34.0 30.4 32.1 27.4 33.2 34.0 2.1 0.0 15.2 16.0 16.5 14.5 23.2 52.8 17.1 14.6 40.0 29.6 30.5 22.8 31.2 75.4 10.4 163.7 21.7 15.9 9.8 58.1 4.1 14.0 22.2 2.9 43.0 3.2 4.3 80.4 182.7 56.0 25.5 42.4 10.2 27.4 4.2 64.0 18.5 43.7 9.2 57.8 36.7 2.4 9.1 7.1 24.8 2.3 67.6 5.6 1.8 56.8 9.2 5.5 3.7 65.6 32.7 63.2 123.6 42.3 60.7 20.6 14.6 11.5 26.3 19.3 27.1 11.9 6.3 14.2 11.1 310.3 9.7 46.3 14.3 33.0 CHPT1 CPT1 ENSG00000111666 "Choline phosphotransferase 1" Q8WUD6 12 101696947-101744140 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 344.4;Late spermatids: 650.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 36.9;eosinophil: 14.6" "Lineage enriched" "Detected in all" 8 "granulocytes: 36.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067643 Approved Supported Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "HPA067643: " "unprognostic (1.59e-3)" "unprognostic (1.02e-1)" "unprognostic (1.91e-1)" "unprognostic (9.48e-2)" "unprognostic (3.15e-1)" "unprognostic (9.17e-2)" "unprognostic (5.79e-2)" "unprognostic (4.83e-2)" "unprognostic (1.12e-1)" "unprognostic (4.70e-1)" "unprognostic (5.27e-2)" "unprognostic (1.16e-2)" "unprognostic (1.52e-2)" "unprognostic (3.35e-1)" "unprognostic (1.72e-1)" "prognostic favorable (7.41e-4)" "unprognostic (1.79e-1)" 39.8 47.7 48.6 17.7 49.1 62.0 102.9 43.8 65.6 50.5 41.9 49.4 88.1 19.2 56.1 24.9 33.4 40.2 91.3 46.1 47.3 73.5 157.4 38.4 20.0 50.0 51.2 18.7 25.0 92.4 12.4 22.8 44.9 35.0 48.9 4.8 130.0 50.0 27.8 28.0 75.7 18.8 50.0 23.5 56.0 28.1 54.4 9.0 38.0 28.3 21.2 32.4 26.2 48.9 11.3 51.2 13.7 29.3 106.6 35.7 38.9 40.2 46.2 39.7 25.5 19.3 7.7 17.3 22.1 55.1 54.3 16.9 83.8 14.2 37.3 26.2 70.1 69.7 25.7 112.6 59.4 34.8 13.5 33.6 4.1 18.0 32.7 59.0 20.0 36.4 102.8 43.1 39.4 27.6 20.8 118.5 36.2 53.8 67.4 15.9 26.8 12.4 17.9 43.4 13.8 10.4 37.2 52.3 103.2 21.4 53.8 23.6 14.7 36.1 18.7 28.5 39.9 24.3 7.9 21.2 28.4 39.7 53.4 36.9 2.2 14.6 0.6 1.7 0.6 4.4 1.2 0.9 2.9 2.6 0.4 0.6 3.1 4.6 2.2 3.7 0.6 0.5 48.6 49.1 43.8 65.6 46.1 47.3 50.0 51.2 44.9 50.0 54.4 48.9 27.1 48.1 27.6 159.6 135.1 37.5 313.3 4.2 21.6 19.3 243.8 76.7 45.3 102.9 13.1 64.4 29.2 123.9 32.6 61.7 70.5 8.1 344.4 17.1 50.2 22.5 21.1 168.6 95.8 13.8 56.1 75.4 69.8 21.0 10.8 15.3 31.1 189.7 56.4 35.3 95.6 53.4 2.0 102.9 55.7 650.9 85.4 81.2 145.9 36.5 27.0 68.1 5.2 65.9 10.2 9.6 113.3 89.1 55.4 172.1 174.1 183.7 4.3 16.0 19.7 88.2 37.8 193.8 43.2 43.1 43.2 60.3 41.3 3.4 90.7 291.6 CHRDL2 BNF1 ENSG00000054938 "Chordin like 2" Q6WN34 11 74696429-74731426 "Predicted intracellular proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 145.1;gallbladder: 106.0;lymphoid tissue: 115.8;smooth muscle: 122.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 194.1;Hepatocytes: 112.2;Skeletal myocytes: 533.4" "Cancer enhanced" "Detected in many" "stomach cancer: 14.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 2.4;PC-3: 1.3;SiHa: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA021771, HPA076522" Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 9700000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 20: HeLa - Mitochondria" "Cluster 30: Mammary glandular cells - Lactation" Vesicles "HPA021771: AB_1846689, HPA076522: " "unprognostic (2.38e-2)" "unprognostic (1.80e-1)" "unprognostic (7.24e-2)" "unprognostic (3.41e-3)" "unprognostic (9.45e-2)" "unprognostic (2.09e-1)" "unprognostic (4.08e-2)" "unprognostic (4.33e-2)" "unprognostic (6.64e-2)" "unprognostic (2.57e-1)" "unprognostic (1.86e-1)" "unprognostic (1.23e-1)" "unprognostic (7.58e-6)" "unprognostic (8.39e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (6.08e-4)" 2.7 0.2 0.6 115.8 0.4 0.0 5.1 0.4 0.7 64.7 0.1 88.7 4.1 145.1 0.8 4.1 9.4 106.0 24.4 0.4 0.6 5.2 46.3 2.9 0.4 1.0 0.6 2.5 3.1 0.4 0.4 4.5 0.7 22.6 2.6 0.5 0.5 8.9 6.6 1.2 10.8 122.1 2.3 1.3 57.7 3.4 0.7 0.0 0.9 4.8 2.8 46.3 21.2 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.4 2.4 0.3 0.0 0.5 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.2 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.4 0.7 0.4 0.6 1.0 0.6 0.7 2.3 0.7 0.2 1.2 0.0 2.6 0.7 0.3 0.3 0.5 0.2 0.0 0.0 194.1 3.8 2.2 15.7 0.1 9.2 0.0 0.0 0.8 0.0 0.0 13.8 31.4 0.6 0.2 2.1 0.0 0.0 0.1 10.3 0.1 5.3 0.0 0.5 0.0 0.2 2.9 112.2 0.1 0.0 0.2 0.0 0.0 2.4 0.0 2.4 0.0 1.1 0.0 1.0 0.0 0.0 0.0 0.5 0.1 4.1 0.0 0.7 0.1 0.9 0.0 0.0 0.0 0.0 0.0 533.4 1.2 0.6 4.3 0.0 0.0 0.1 0.5 0.4 0.0 0.5 CHST7 "C6ST-2, C6ST2" ENSG00000147119 "Carbohydrate sulfotransferase 7" Q9NS84 X 46573765-46598496 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 35.3" "Cell type enhanced" "Detected in many" "Langerhans cells: 45.4;monocytes: 55.5;Peritubular cells: 60.2;Sertoli cells: 52.6;Skeletal myocytes: 43.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 18.5" "Group enriched" "Detected in many" 10 "granulocytes: 10.9;monocytes: 10.2;T-cells: 18.5" "Cell line enhanced" "Detected in many" "EFO-21: 22.8;NTERA-2: 20.5;PC-3: 17.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA003919, HPA030503" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 9800 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 89: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Vesicles" "HPA003919: AB_10601258, HPA030503: " "unprognostic (3.16e-1)" "prognostic favorable (7.20e-4)" "unprognostic (1.11e-1)" "unprognostic (2.66e-1)" "unprognostic (1.82e-2)" "unprognostic (7.85e-2)" "unprognostic (9.82e-3)" "unprognostic (3.52e-2)" "unprognostic (2.61e-1)" "unprognostic (2.81e-1)" "unprognostic (2.39e-3)" "unprognostic (6.71e-2)" "unprognostic (1.19e-1)" "unprognostic (8.85e-3)" "unprognostic (8.28e-2)" "unprognostic (1.50e-1)" "unprognostic (4.39e-2)" 13.2 3.4 5.4 1.7 7.3 2.5 7.5 6.4 7.0 11.2 3.7 3.7 0.8 5.8 0.4 2.5 4.9 1.9 17.4 5.4 7.1 4.0 7.5 3.6 1.8 6.1 7.3 35.3 2.0 1.2 4.2 2.0 6.0 4.1 0.8 0.9 3.5 1.4 4.4 7.3 4.0 1.4 4.7 10.2 3.4 2.1 8.0 1.4 5.8 3.9 0.7 4.5 7.7 4.0 5.5 4.7 3.9 3.5 10.8 7.5 0.2 7.6 5.4 2.0 2.6 1.2 2.1 0.0 22.8 3.1 1.3 4.1 3.8 1.3 1.7 3.2 8.1 1.1 0.3 4.1 16.6 1.9 0.1 2.5 1.1 3.8 3.1 3.4 6.2 2.5 0.0 4.7 1.5 2.6 0.7 2.4 20.5 0.4 17.0 3.6 3.2 10.3 5.5 0.2 8.8 3.4 1.1 0.2 0.9 9.6 1.3 0.4 1.4 6.1 0.6 3.3 3.5 11.0 2.4 1.7 6.8 0.1 0.4 2.4 2.2 0.7 1.5 7.1 1.4 1.2 5.8 2.8 1.2 0.6 1.2 1.1 10.9 0.6 10.2 0.8 18.5 1.9 5.4 7.3 6.4 7.0 5.4 7.1 6.1 7.3 6.0 4.7 8.0 4.0 33.8 0.0 3.1 22.9 2.5 12.4 2.0 4.8 1.2 0.8 2.2 3.7 7.4 10.0 2.6 1.8 0.0 5.3 11.5 1.7 1.9 2.8 0.0 3.6 20.8 16.3 0.0 0.0 0.9 2.5 4.3 23.6 0.0 1.6 0.0 19.7 15.7 4.5 11.5 3.3 4.1 2.9 0.0 14.2 45.4 0.3 19.0 14.1 14.2 4.7 55.5 5.2 4.1 13.0 1.0 1.8 1.5 60.2 4.7 6.7 0.7 2.1 1.9 0.8 52.6 43.1 11.2 0.5 1.3 1.3 13.2 1.4 9.9 11.4 0.9 3.3 CIC KIAA0306 ENSG00000079432 "Capicua transcriptional repressor" Q96RK0 19 42268537-42295797 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026388, HPA044341, HPA064725" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm Vesicles "CAB026388: , HPA044341: AB_2678901, HPA064725: AB_2685335" "unprognostic (2.02e-2)" "unprognostic (4.08e-1)" "unprognostic (1.41e-2)" "unprognostic (3.54e-3)" "unprognostic (3.67e-1)" "unprognostic (4.17e-3)" "unprognostic (1.49e-1)" "unprognostic (2.06e-1)" "unprognostic (4.87e-1)" "unprognostic (1.85e-2)" "unprognostic (1.72e-3)" "unprognostic (3.10e-1)" "unprognostic (4.23e-2)" "unprognostic (1.00e-1)" "unprognostic (2.38e-1)" "unprognostic (1.88e-2)" "unprognostic (1.56e-1)" 41.9 41.5 43.3 23.4 36.1 31.8 42.7 40.7 47.4 53.8 2.3 45.6 15.6 62.3 8.7 34.3 49.1 16.1 35.4 36.3 27.7 41.7 44.6 40.8 24.2 39.5 27.8 70.1 39.4 12.2 58.7 12.6 35.7 40.5 5.8 13.5 35.4 18.7 45.2 47.2 36.9 16.0 17.4 46.9 38.6 74.6 29.4 21.0 44.3 15.3 13.5 39.6 37.5 32.5 31.8 56.7 26.4 34.4 16.6 30.7 10.7 22.8 22.5 22.9 20.9 18.5 21.4 26.7 20.8 21.8 19.6 16.6 14.6 38.9 7.6 61.9 19.6 22.2 44.7 23.0 20.1 11.8 50.9 36.7 25.5 24.4 15.5 24.8 19.2 15.9 21.8 52.5 13.3 31.9 25.1 25.6 16.2 12.6 5.8 21.5 21.2 14.3 20.5 25.3 33.6 27.1 23.7 15.7 21.6 8.3 18.3 25.8 27.5 52.0 43.7 15.9 33.2 41.0 29.8 18.1 37.9 19.4 32.6 0.0 0.5 0.1 0.7 0.8 0.5 0.5 0.3 0.5 0.5 0.6 0.2 0.4 1.1 0.2 0.6 0.6 0.1 0.6 43.3 36.1 40.7 47.4 36.3 27.7 39.5 27.8 35.7 17.4 29.4 32.5 27.8 0.0 3.0 15.7 13.7 25.9 12.8 16.2 27.9 38.3 20.7 16.9 7.8 21.5 7.1 9.2 20.9 6.9 9.1 14.2 3.9 13.4 5.1 14.6 14.9 20.3 14.8 8.4 8.0 15.3 5.1 11.2 17.9 22.3 12.0 11.1 13.9 19.2 11.9 42.1 9.0 10.1 10.2 18.0 23.6 3.3 21.8 15.3 24.9 7.5 13.0 18.4 8.2 4.0 10.3 16.9 11.2 18.0 10.4 11.3 10.6 6.2 8.0 18.8 26.3 19.9 17.6 19.4 20.2 16.5 19.5 13.0 13.2 14.2 10.6 11.9 CITED4 ENSG00000179862 "Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4" Q96RK1 1 40861054-40862363 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 172.1;Breast glandular cells: 183.7;Breast myoepithelial cells: 225.0;Cholangiocytes: 258.7;Endometrial ciliated cells: 350.4;Glandular and luminal cells: 202.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 91.3;THP-1: 264.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA056434 Approved Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" Vesicles "HPA056434: AB_2683132" "unprognostic (5.39e-3)" "unprognostic (5.41e-2)" "unprognostic (1.53e-1)" "prognostic favorable (4.38e-5)" "unprognostic (3.43e-3)" "unprognostic (1.90e-2)" "unprognostic (3.44e-3)" "unprognostic (3.42e-2)" "unprognostic (2.67e-1)" "unprognostic (1.98e-3)" "unprognostic (2.25e-2)" "unprognostic (6.00e-2)" "unprognostic (2.29e-3)" "unprognostic (2.10e-1)" "unprognostic (2.11e-1)" "unprognostic (2.11e-1)" "unprognostic (6.13e-2)" 13.7 15.1 9.3 1.1 10.6 19.1 30.3 9.4 9.5 18.0 4.3 28.9 1.6 17.1 2.4 29.0 14.4 1.9 26.6 6.6 14.5 20.4 38.8 11.4 1.7 14.6 15.4 10.3 49.1 4.4 4.9 1.7 10.6 16.4 0.4 0.8 34.2 8.5 33.0 51.5 7.7 2.3 12.0 29.9 13.4 25.4 13.1 1.2 7.3 9.2 1.3 8.9 23.7 10.5 29.5 5.7 1.6 34.6 0.7 1.3 34.4 1.9 2.1 0.7 0.8 3.0 38.5 0.1 4.6 0.5 1.0 44.6 2.4 24.0 0.6 0.1 0.4 0.2 3.3 4.9 5.9 1.0 0.4 4.2 10.1 2.3 7.6 2.8 1.8 0.4 0.1 0.1 1.3 0.9 0.5 19.6 11.1 0.9 3.9 0.3 0.0 0.1 91.3 16.9 6.7 1.9 1.4 35.8 2.0 3.7 17.4 264.9 2.3 0.0 0.0 0.4 1.1 0.0 0.8 0.0 0.0 13.8 0.9 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.0 9.3 10.6 9.4 9.5 6.6 14.5 14.6 15.4 10.6 12.0 13.1 10.5 17.4 9.6 1.1 1.3 4.0 19.1 172.1 2.1 37.0 4.0 183.7 225.0 10.4 258.7 3.5 22.0 0.0 1.0 11.9 3.7 43.0 14.2 47.9 350.4 24.4 48.9 7.7 9.7 2.0 43.6 0.9 14.0 17.9 202.6 0.0 30.5 11.4 43.1 1.3 1.7 1.7 4.8 2.0 10.4 3.2 64.8 5.0 13.7 19.6 1.0 4.6 46.1 2.1 2.0 3.8 33.0 3.4 5.7 2.4 65.6 0.2 88.0 6.5 3.0 19.7 72.2 19.7 0.9 1.5 49.9 24.3 0.1 14.6 37.3 3.6 122.3 CKLF "C32, CKLF1, CKLF3, CKLF4, HSPC224, UCK-1" ENSG00000217555 "Chemokine like factor" Q9UBR5 16 66552563-66566251 "Predicted membrane proteins, Predicted secreted proteins" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 345.1;Spermatocytes: 300.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1384.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA062779 Approved Vesicles "Secreted to blood" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA062779: AB_2684867" "unprognostic (1.64e-2)" "unprognostic (2.17e-2)" "unprognostic (1.88e-1)" "unprognostic (4.97e-2)" "unprognostic (3.06e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (5.67e-5)" "unprognostic (2.72e-1)" "unprognostic (3.35e-1)" "unprognostic (1.79e-2)" "unprognostic (8.05e-3)" "unprognostic (1.48e-1)" "prognostic unfavorable (1.06e-9)" "unprognostic (2.36e-1)" "unprognostic (2.65e-1)" "prognostic favorable (2.22e-4)" "unprognostic (1.07e-1)" 36.5 31.1 26.3 54.8 26.2 68.2 36.0 27.4 29.8 27.7 25.9 42.1 31.8 23.8 27.4 19.2 31.1 40.3 16.5 25.7 28.8 21.0 29.6 36.2 61.5 28.1 27.6 25.6 17.9 58.0 19.7 29.7 28.9 15.5 42.5 9.7 19.7 18.4 14.8 16.9 38.7 33.5 27.9 67.0 25.6 56.8 26.4 90.0 23.7 20.1 51.2 46.1 20.0 29.6 194.6 169.2 34.7 101.5 92.7 76.1 25.5 95.2 72.4 101.7 150.9 158.8 231.4 75.8 116.6 81.8 106.4 102.5 70.5 57.2 142.1 94.2 35.3 55.5 145.0 197.3 56.0 175.7 144.1 52.0 45.3 126.9 44.9 122.1 122.8 229.4 90.8 212.8 129.2 64.8 169.9 172.1 11.5 114.0 273.1 287.5 184.2 215.6 343.2 106.3 48.8 58.8 290.5 19.3 93.0 23.3 55.5 116.5 76.6 146.5 131.8 51.0 113.5 100.3 224.0 393.0 123.5 151.5 121.1 807.1 380.9 773.3 187.6 203.9 238.9 100.6 174.8 186.6 317.6 97.7 92.7 126.4 1384.5 187.6 199.2 161.6 236.0 401.2 26.3 26.2 27.4 29.8 25.7 28.8 28.1 27.6 28.9 27.9 26.4 29.6 65.7 19.2 49.0 0.0 68.7 27.3 24.7 84.2 12.0 8.4 80.8 94.0 1.8 87.2 50.8 57.0 0.0 54.8 109.7 57.1 17.6 141.4 67.7 34.8 21.5 52.4 33.0 63.5 0.0 130.0 117.7 38.6 21.4 17.5 345.1 17.7 67.5 38.4 247.4 1.7 0.0 73.6 61.1 138.2 238.4 31.4 49.4 244.2 40.9 0.0 157.8 28.1 188.4 0.0 0.0 224.2 51.3 30.1 94.6 10.0 95.9 83.4 79.3 9.0 32.9 24.5 38.1 300.0 77.1 30.8 23.0 17.4 192.6 23.9 79.0 25.8 CKS1B "CKS1, ckshs1" ENSG00000173207 "CDC28 protein kinase regulatory subunit 1B" P61024 1 154974653-154979251 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 651.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003424, HPA030762" Approved Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA Yes "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitochondria, Cytosol" "Nucleoplasm, Vesicles" "HPA003424: AB_2666948, HPA030762: AB_10670044" "unprognostic (1.06e-2)" "unprognostic (1.62e-1)" "unprognostic (2.84e-1)" "prognostic unfavorable (7.89e-4)" "unprognostic (1.34e-1)" "unprognostic (2.59e-2)" "prognostic unfavorable (2.94e-5)" "unprognostic (2.01e-3)" "prognostic unfavorable (3.12e-5)" "unprognostic (3.63e-2)" "prognostic unfavorable (6.13e-4)" "unprognostic (3.19e-1)" "prognostic unfavorable (6.03e-7)" "unprognostic (3.12e-2)" "unprognostic (1.44e-1)" "prognostic favorable (4.87e-4)" "unprognostic (1.37e-1)" 59.0 31.9 15.0 33.6 15.8 117.7 67.8 16.4 19.8 44.3 15.0 49.4 40.8 35.0 36.8 61.6 40.9 22.2 35.5 15.4 16.2 37.9 73.3 29.0 71.3 17.5 15.8 31.7 22.4 35.5 18.4 50.6 17.7 26.1 50.5 6.0 28.4 32.9 14.5 51.2 44.3 34.8 17.4 37.0 35.5 48.6 15.7 88.7 30.1 23.5 74.1 30.1 42.6 18.8 459.2 616.5 455.9 245.3 66.9 68.1 361.4 209.1 166.8 463.4 367.8 599.9 653.4 433.8 345.9 143.2 251.2 410.6 468.0 305.2 428.7 392.9 293.9 294.6 249.9 426.5 19.4 359.7 257.9 39.8 132.2 391.4 532.8 91.5 232.5 298.2 486.6 566.8 353.9 452.8 337.3 273.9 575.3 442.1 547.6 334.8 373.6 554.3 165.6 164.2 184.3 463.9 313.6 292.0 347.3 530.2 391.6 492.9 126.0 282.5 292.4 237.0 505.3 348.9 734.7 617.0 179.6 300.1 399.8 2.2 13.0 6.9 19.8 82.0 24.4 74.2 28.0 27.1 22.1 70.4 34.0 32.8 1.7 28.7 105.4 92.6 33.3 28.1 15.0 15.8 16.4 19.8 15.4 16.2 17.5 15.8 17.7 17.4 15.7 18.8 31.7 12.8 33.3 1.3 46.5 217.6 101.3 170.6 74.0 3.4 90.6 140.5 9.2 87.2 63.1 29.5 0.0 224.0 40.7 48.3 80.3 93.0 15.8 43.1 24.6 51.9 20.4 140.1 0.8 112.1 651.8 84.6 20.9 28.3 21.0 66.7 29.6 89.8 132.1 1.7 0.8 57.4 120.1 46.0 121.0 21.7 76.1 37.4 113.8 0.0 41.3 20.7 20.6 0.5 3.5 119.0 41.7 45.9 38.4 130.2 63.1 87.5 52.1 3.0 19.7 50.6 53.0 124.7 151.0 74.9 203.6 131.9 40.7 27.2 80.0 99.5 CKS2 ENSG00000123975 "CDC28 protein kinase regulatory subunit 2" P33552 9 89311195-89316703 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 177.3;testis: 186.3" "Cell type enhanced" "Detected in many" "Langerhans cells: 474.6;Spermatocytes: 692.7;Spermatogonia: 503.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 187.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003424, HPA030762" Approved Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" "Mitochondria, Cytosol" "Nucleoplasm, Vesicles" "HPA003424: AB_2666948, HPA030762: AB_10670044" "unprognostic (8.30e-2)" "unprognostic (3.00e-1)" "unprognostic (1.50e-2)" "unprognostic (2.80e-2)" "unprognostic (2.96e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (2.51e-6)" "unprognostic (3.57e-3)" "unprognostic (7.04e-2)" "unprognostic (1.34e-2)" "prognostic unfavorable (6.85e-4)" "unprognostic (1.24e-2)" "prognostic unfavorable (1.78e-5)" "unprognostic (2.13e-3)" "unprognostic (1.44e-1)" "unprognostic (2.84e-1)" "unprognostic (1.84e-1)" 13.6 82.9 9.6 38.5 10.0 177.3 20.1 11.9 26.9 10.1 11.8 44.1 43.3 13.0 8.8 53.2 12.1 18.7 10.3 12.7 10.3 35.6 31.2 24.0 102.8 10.5 10.1 9.4 4.2 19.8 4.8 44.3 11.0 15.0 41.0 27.9 10.8 17.8 9.4 19.9 33.1 17.6 10.6 32.6 20.4 186.3 10.8 121.1 12.8 4.8 84.7 26.5 19.9 11.3 685.9 570.1 342.6 230.6 98.7 89.1 249.5 396.1 211.4 428.1 340.0 236.1 328.6 504.9 228.4 149.1 761.4 466.5 415.5 305.1 488.2 398.1 335.5 257.5 378.9 637.5 42.4 531.7 281.2 33.0 69.2 307.2 269.1 162.9 403.2 409.1 313.2 430.6 556.0 509.1 420.7 928.3 501.6 795.5 521.5 358.4 376.4 303.7 342.8 153.5 288.4 171.7 328.7 314.9 324.5 318.4 379.7 304.2 231.4 184.1 350.3 449.6 588.2 345.9 759.2 415.3 271.3 303.1 268.5 40.8 19.5 44.1 22.6 26.5 25.3 61.3 30.4 21.9 22.5 44.7 16.3 21.8 14.5 40.9 14.8 187.9 62.7 23.6 9.6 10.0 11.9 26.9 12.7 10.3 10.5 10.1 11.0 10.6 10.8 11.3 138.6 38.5 103.9 0.3 175.7 280.2 92.1 126.1 259.0 4.1 107.2 169.0 61.3 5.7 49.9 14.7 0.0 231.1 201.1 79.4 23.5 20.1 37.3 149.7 66.4 66.1 122.3 266.9 1.2 11.2 379.4 63.1 74.9 250.2 145.0 144.7 29.3 25.0 184.6 0.0 1.9 164.9 111.9 40.5 474.6 77.0 25.7 164.3 140.5 1.9 31.0 26.1 28.8 1.0 1.1 31.1 67.1 16.6 89.3 72.1 37.6 209.7 32.8 7.3 46.0 75.2 206.5 692.7 503.6 197.5 299.1 199.5 156.0 70.3 162.7 102.1 CLCF1 "BSF-3, BSF3, CISS2, CLC, NNT-1, NNT1, NR6" ENSG00000175505 "Cardiotrophin like cytokine factor 1" Q9UBD9 11 67364168-67374177 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted secreted proteins" Cytokine "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 41.8;Glandular and luminal cells: 104.9;Pancreatic endocrine cells: 56.2;Prostatic glandular cells: 56.4;Urothelial cells: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SiHa: 57.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA042444 Uncertain Approved "Nuclear bodies,Vesicles" "Secreted to blood" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 72: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 44: Endometrium - Transcription" "Nuclear bodies, Vesicles" "HPA042444: AB_10794527" "unprognostic (2.68e-1)" "unprognostic (7.87e-3)" "unprognostic (6.21e-3)" "unprognostic (2.62e-2)" "prognostic unfavorable (9.91e-4)" "unprognostic (1.61e-2)" "unprognostic (1.09e-3)" "unprognostic (1.47e-2)" "unprognostic (5.08e-2)" "unprognostic (2.65e-2)" "unprognostic (1.84e-2)" "unprognostic (1.54e-1)" "unprognostic (1.67e-2)" "unprognostic (1.45e-2)" "unprognostic (1.10e-1)" "unprognostic (1.17e-2)" "unprognostic (2.37e-1)" 16.2 6.0 1.3 8.0 0.5 13.7 5.3 0.0 1.5 13.9 0.9 13.4 1.4 16.6 1.0 4.4 17.1 17.7 8.8 1.0 0.6 19.0 4.2 9.3 5.3 1.4 0.5 6.7 6.5 0.2 6.5 4.2 0.4 7.2 1.7 1.4 9.1 1.8 1.5 2.6 9.4 8.3 0.0 8.1 11.2 1.9 2.1 0.7 9.7 1.9 4.4 18.1 7.6 0.2 15.1 31.4 2.2 9.7 4.2 5.8 0.0 20.9 11.6 14.4 7.0 5.1 40.3 9.1 17.1 26.8 17.5 10.3 0.4 10.7 6.3 0.5 0.3 0.1 23.9 4.0 13.6 1.9 2.4 7.6 2.6 15.0 6.5 27.4 3.1 0.0 3.5 0.4 15.0 12.0 0.1 6.8 8.1 18.9 28.8 0.9 4.8 0.5 22.7 0.8 0.1 1.6 57.8 2.2 1.3 4.4 1.3 2.5 12.5 27.6 11.6 35.4 31.5 2.0 0.1 1.0 35.4 1.8 11.1 0.0 0.9 15.2 10.5 3.4 6.2 10.8 4.8 8.3 1.3 13.8 0.1 3.5 0.3 0.2 10.5 0.0 1.1 3.2 1.3 0.5 0.0 1.5 1.0 0.6 1.4 0.5 0.4 0.0 2.1 0.2 4.2 16.0 4.8 1.3 10.6 3.7 25.9 6.5 1.8 0.0 14.5 2.4 0.8 25.8 9.6 7.3 0.0 0.4 10.0 3.8 1.9 24.0 1.8 41.8 19.4 6.2 1.2 0.0 0.7 11.8 0.6 14.0 5.1 104.9 3.8 2.1 2.9 1.0 1.2 0.0 0.5 2.3 6.1 0.3 10.7 4.7 3.4 6.7 8.8 1.0 6.5 1.7 3.1 0.5 0.1 56.2 14.3 0.0 9.5 56.4 0.2 5.2 1.7 0.3 0.0 32.6 10.4 0.3 0.9 1.6 4.4 0.1 9.7 0.1 1.5 65.2 CLCN3 "ClC-3, CLC3" ENSG00000109572 "Chloride voltage-gated channel 3" P51790 4 169612633-169723673 "Predicted intracellular proteins, Predicted membrane proteins" "Antiport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044723 Approved Supported Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA044723: AB_10959733" "unprognostic (1.92e-1)" "unprognostic (3.92e-2)" "unprognostic (1.95e-3)" "unprognostic (1.38e-2)" "unprognostic (1.64e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (2.25e-1)" "unprognostic (3.32e-1)" "unprognostic (1.79e-1)" "unprognostic (5.40e-2)" "unprognostic (1.30e-1)" "prognostic favorable (1.10e-4)" "unprognostic (2.49e-2)" "unprognostic (2.49e-1)" "unprognostic (1.45e-1)" "unprognostic (6.38e-3)" 21.1 34.5 20.1 20.6 28.7 12.3 31.9 29.1 30.2 23.9 20.5 47.5 30.1 18.7 29.4 40.7 26.4 38.0 35.3 22.8 30.5 36.4 25.7 21.2 17.3 32.3 41.0 23.1 41.0 37.2 18.2 24.1 32.1 32.7 52.6 78.3 78.0 21.8 24.7 29.1 29.8 17.8 32.3 16.7 41.2 33.3 26.5 21.0 37.0 22.1 24.5 37.4 17.1 42.0 32.6 33.2 48.7 62.1 96.1 80.8 24.0 42.9 53.5 28.3 34.3 23.7 72.2 40.0 26.1 35.9 32.7 27.2 61.2 26.6 46.9 35.9 24.4 33.8 50.6 27.3 65.8 41.0 54.2 56.6 59.7 50.5 49.5 117.4 51.7 55.2 85.1 88.0 49.7 11.8 56.2 9.4 20.0 56.2 22.4 25.0 21.5 31.6 58.1 66.6 51.9 51.5 38.4 40.9 66.9 39.3 27.9 19.2 43.5 22.5 25.3 36.5 33.7 39.3 64.3 35.5 67.6 15.4 60.8 3.8 4.1 2.9 5.0 4.8 6.5 5.0 3.7 4.7 5.7 3.8 5.7 5.2 2.9 4.5 4.0 7.1 4.7 4.7 20.1 28.7 29.1 30.2 22.8 30.5 32.3 41.0 32.1 32.3 26.5 42.0 35.5 32.1 26.2 58.8 30.7 11.3 25.7 21.5 20.5 90.3 54.6 27.9 66.5 42.9 25.3 62.5 131.3 23.8 23.1 118.3 7.9 37.2 88.1 46.9 35.9 35.2 66.9 83.1 102.4 44.3 18.7 29.5 51.5 51.8 113.0 32.3 38.6 39.3 18.6 60.6 126.1 64.2 20.3 32.9 9.8 67.4 24.5 47.8 32.0 44.0 17.1 136.7 28.8 139.7 141.5 31.9 55.3 21.1 21.4 45.3 37.1 17.9 67.8 115.1 6.6 34.6 21.5 17.2 15.5 42.8 26.1 71.1 21.0 67.0 65.4 34.0 CLCN4 "ClC-4, CLC4" ENSG00000073464 "Chloride voltage-gated channel 4" P51793 X 10156975-10237660 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Transport" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 33.3;retina: 37.9;skeletal muscle: 45.0;tongue: 34.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 85.0;Cone photoreceptor cells: 102.2;Excitatory neurons: 45.7;Horizontal cells: 52.2;Inhibitory neurons: 54.0;Oligodendrocytes: 76.5;Rod photoreceptor cells: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.6;neutrophil: 2.2" "Group enriched" "Detected in many" 6 "B-cells: 2.6;granulocytes: 2.2" "Cell line enhanced" "Detected in many" "GAMG: 25.3;HEL: 24.3;SCLC-21H: 24.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031313, HPA063637" Enhanced Approved Approved Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA031313: AB_10601358, HPA063637: AB_2685069" "unprognostic (1.01e-1)" "unprognostic (1.20e-2)" "unprognostic (5.07e-2)" "prognostic unfavorable (2.13e-5)" "unprognostic (2.96e-1)" "unprognostic (3.75e-1)" "unprognostic (1.04e-2)" "unprognostic (3.66e-1)" "unprognostic (1.75e-1)" "unprognostic (5.99e-2)" "prognostic favorable (9.55e-4)" "unprognostic (9.70e-2)" "unprognostic (9.78e-3)" "unprognostic (1.68e-1)" "unprognostic (1.49e-1)" "unprognostic (1.32e-1)" "unprognostic (1.74e-1)" 2.6 2.7 16.2 1.5 27.4 1.8 1.1 28.8 23.1 1.3 5.2 0.9 0.8 0.6 22.6 1.7 2.9 2.1 12.3 19.6 19.7 2.8 3.2 3.0 2.8 27.1 24.1 1.6 2.2 10.8 5.3 1.1 24.5 1.5 0.7 37.9 2.2 1.0 45.0 1.0 0.7 0.7 18.5 2.6 1.5 1.8 26.8 2.6 6.5 34.2 1.8 1.2 0.7 33.3 5.9 4.6 2.7 0.0 1.5 2.5 0.1 0.2 0.0 0.0 0.0 9.1 4.6 5.0 13.0 1.5 25.3 1.4 1.4 2.9 0.2 0.1 5.7 24.3 2.2 3.5 7.3 0.0 0.1 12.9 3.4 7.0 1.5 4.7 9.4 0.0 1.5 0.1 3.3 1.1 0.0 0.2 4.0 7.1 15.3 0.0 4.5 0.0 2.1 0.8 24.1 8.7 8.6 1.1 0.0 2.7 1.7 2.7 7.4 3.1 5.8 15.3 0.6 0.5 12.1 1.8 10.5 0.0 4.5 1.6 0.3 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.4 2.6 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.3 16.2 27.4 28.8 23.1 19.6 19.7 27.1 24.1 24.5 18.5 26.8 33.3 1.0 9.6 3.1 11.8 4.9 0.5 0.6 2.0 0.0 85.0 1.1 0.4 31.1 8.6 2.2 7.3 102.2 0.2 0.0 0.1 0.0 2.5 0.1 2.6 1.3 3.0 15.0 9.4 45.7 3.6 0.1 4.0 1.1 3.1 1.3 0.7 13.6 5.1 3.1 52.2 54.0 0.6 4.1 4.8 2.3 0.0 0.9 3.4 0.0 15.9 1.0 15.4 0.0 24.6 76.5 4.1 0.1 3.8 0.4 0.8 0.0 2.9 5.3 42.6 0.0 8.7 6.0 0.0 0.5 0.2 0.1 0.3 0.1 2.6 0.3 1.3 CLDN14 DFNB29 ENSG00000159261 "Claudin 14" O95500 21 36460621-36576569 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 22 "kidney: 13.8;liver: 39.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 7.2;Distal tubular cells: 19.6;Ductal cells: 11.8;Exocrine glandular cells: 8.2;Hepatocytes: 22.2;Pancreatic endocrine cells: 21.3" "Cancer enriched" "Detected in many" 6 "liver cancer: 7.9" "Region enriched" "Detected in single" 5 "cerebral cortex: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 14 "HDLM-2: 224.1" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA054707 Uncertain Vesicles NA NA "Cluster 85: Liver - Metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA054707: " "unprognostic (1.14e-1)" "unprognostic (2.21e-1)" "unprognostic (3.74e-2)" "unprognostic (9.43e-2)" "unprognostic (8.20e-3)" "unprognostic (5.54e-2)" "prognostic favorable (1.53e-4)" "unprognostic (3.50e-4)" "unprognostic (2.28e-1)" "unprognostic (2.30e-2)" "unprognostic (2.12e-2)" "unprognostic (4.87e-1)" "unprognostic (7.44e-4)" "unprognostic (2.77e-2)" "unprognostic (7.65e-2)" "unprognostic (2.45e-2)" "unprognostic (9.71e-2)" 0.1 0.0 0.2 0.3 0.0 0.0 0.3 0.0 1.1 0.0 0.0 0.1 0.1 0.1 0.4 0.0 0.0 0.3 0.1 0.1 0.0 13.8 39.5 0.1 0.0 0.1 0.0 0.0 1.0 0.1 0.0 0.2 0.1 0.0 0.1 0.3 0.2 0.0 0.4 0.4 0.1 0.0 0.0 0.2 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.4 0.0 0.0 0.0 0.0 224.1 0.0 0.0 0.0 0.1 0.0 0.0 3.3 0.0 0.0 0.1 0.0 0.7 2.1 0.1 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 2.5 15.8 0.0 0.0 0.0 0.3 0.0 3.5 0.0 0.0 0.1 7.4 4.2 0.1 0.7 0.4 6.7 15.7 0.0 1.0 0.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.5 0.4 1.0 0.6 0.0 0.0 0.8 0.4 0.7 7.2 0.1 1.8 0.0 0.1 0.0 0.7 19.6 11.8 0.6 0.3 0.2 3.6 0.0 0.0 0.6 8.2 1.3 0.1 0.0 3.4 0.0 0.0 0.4 22.2 0.1 0.0 0.4 0.6 0.0 0.6 0.0 0.5 0.0 0.2 3.6 0.0 0.6 0.0 0.0 1.5 1.0 21.3 0.0 0.4 6.9 0.6 0.0 0.7 0.0 0.0 0.0 0.0 2.0 1.2 0.0 0.0 0.3 0.8 1.4 0.0 0.3 2.3 CLDN23 CLDNL ENSG00000253958 "Claudin 23" Q96B33 8 8701937-8704096 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 16.4;stomach 1: 15.6" "Group enriched" "Detected in many" 4 "Distal enterocytes: 418.8;Paneth cells: 449.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.3;plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 7.7;Daudi: 6.4;RT4: 6.7;SK-BR-3: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA061306 Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Plasma membrane, Cell Junctions" "HPA061306: " "unprognostic (1.86e-1)" "unprognostic (1.53e-1)" "prognostic favorable (3.46e-4)" "unprognostic (2.97e-1)" "unprognostic (8.32e-2)" "unprognostic (3.04e-1)" "unprognostic (3.44e-1)" "unprognostic (2.05e-2)" "unprognostic (2.14e-1)" "unprognostic (1.14e-1)" "unprognostic (1.97e-2)" "unprognostic (8.25e-3)" "prognostic favorable (9.65e-8)" "unprognostic (7.76e-2)" "unprognostic (3.17e-2)" "unprognostic (9.59e-2)" "unprognostic (1.33e-3)" 6.2 1.1 0.3 2.3 0.4 0.1 5.7 0.2 0.3 2.4 2.3 16.4 4.1 1.0 1.9 3.3 1.4 1.2 0.7 0.3 0.3 4.5 10.4 4.7 0.3 0.5 0.4 1.6 4.0 2.1 0.9 1.5 0.4 1.3 6.8 0.1 6.8 1.3 0.5 13.5 10.1 0.3 0.4 1.8 15.6 0.5 0.5 0.1 4.9 0.3 0.3 5.0 2.7 0.6 0.1 2.6 0.0 0.1 0.7 0.1 7.7 1.9 1.5 2.0 3.1 1.5 4.2 6.4 0.0 0.1 0.7 2.5 0.0 0.0 0.2 1.3 0.0 0.0 0.7 0.1 3.5 0.0 0.0 1.0 0.8 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 3.3 0.0 0.2 1.9 0.3 1.3 0.0 0.0 0.0 0.9 6.7 0.3 0.9 2.6 6.8 0.1 0.7 0.9 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.3 0.0 0.9 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.3 0.4 0.2 0.3 0.3 0.3 0.5 0.4 0.4 0.4 0.5 0.6 13.0 9.6 3.1 0.3 1.1 0.1 6.6 4.2 2.2 0.1 6.8 3.4 0.7 30.0 6.9 1.8 0.0 19.1 2.8 418.8 7.9 26.9 0.0 6.0 2.5 3.4 7.7 0.0 0.0 10.7 14.9 3.3 59.7 6.7 4.5 0.8 8.2 10.6 16.8 0.0 0.0 49.9 26.4 2.4 1.4 0.0 0.3 4.6 3.6 1.9 1.4 1.1 0.0 0.0 0.0 28.1 449.9 0.4 0.1 3.3 99.1 4.7 10.3 1.1 6.6 1.5 3.2 0.0 0.0 3.9 0.6 9.4 1.3 0.3 55.2 12.2 CLDN7 "CEPTRL2, CPETRL2, Hs.84359" ENSG00000181885 "Claudin 7" O95471 17 7259903-7263983 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 341.3;intestine: 341.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1391.1;Pancreatic endocrine cells: 822.1;Paneth cells: 1276.4;Proximal enterocytes: 1390.9;Urothelial cells: 975.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 84.1;CACO-2: 90.2;CAPAN-2: 173.2;HaCaT: 364.9;MCF7: 129.8;OE19: 139.6;SK-BR-3: 150.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013063, HPA014703, HPA073662" Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Cell Junctions" "CAB013063: , HPA014703: AB_1846873, HPA073662: " "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (4.12e-2)" "unprognostic (2.90e-1)" "unprognostic (1.05e-1)" "unprognostic (8.67e-2)" "unprognostic (3.41e-2)" "unprognostic (1.98e-2)" "unprognostic (5.64e-3)" "unprognostic (8.34e-2)" "unprognostic (4.89e-3)" "unprognostic (1.62e-2)" "prognostic favorable (8.96e-11)" "prognostic favorable (4.09e-4)" "unprognostic (1.87e-1)" "prognostic favorable (1.85e-4)" "unprognostic (1.62e-1)" 6.7 8.0 0.4 17.6 0.4 0.2 31.2 0.5 0.6 47.3 0.4 341.0 146.7 4.8 43.9 341.3 41.3 27.4 2.7 0.4 0.4 123.8 40.2 61.8 0.8 0.6 0.5 1.5 108.5 49.0 31.1 14.2 0.6 44.5 128.6 1.1 169.2 30.0 1.5 13.1 248.9 6.2 0.5 5.7 5.2 1.9 0.6 2.4 76.7 0.0 21.2 40.5 96.3 0.9 10.8 1.1 0.2 0.3 0.0 0.6 84.1 0.3 0.3 0.0 0.0 90.2 173.2 0.1 3.2 0.4 0.4 364.9 0.1 11.2 0.0 0.1 1.9 0.1 2.4 0.0 6.5 0.1 0.8 1.5 17.3 0.0 0.6 0.0 8.1 0.1 1.0 0.3 0.1 129.8 0.1 1.2 0.6 139.6 3.4 0.2 0.0 2.5 0.1 0.0 20.4 0.4 1.1 150.2 0.0 6.6 55.0 1.3 16.8 0.2 0.6 0.7 0.2 0.1 0.3 0.1 1.2 0.0 0.3 0.0 0.3 0.0 0.5 0.8 1.3 0.1 0.3 0.8 0.4 0.9 0.9 1.7 0.0 0.7 0.0 0.0 0.3 0.5 0.4 0.4 0.5 0.6 0.4 0.4 0.6 0.5 0.6 0.5 0.6 0.9 4.4 112.2 55.6 0.0 7.4 2.0 295.4 316.3 66.6 0.7 200.4 102.4 0.6 240.2 550.3 321.8 8.4 281.3 3.1 1391.1 39.2 787.5 0.1 210.1 26.6 9.0 326.8 4.0 0.0 790.0 342.7 5.2 15.3 225.5 5.7 0.1 3.6 41.2 33.7 0.0 0.0 741.7 362.2 4.1 6.4 0.2 1.2 11.0 24.9 1.9 11.0 1.6 0.0 0.0 0.0 822.1 1276.4 0.0 0.5 406.5 1390.9 78.6 498.5 6.7 0.0 0.2 38.6 0.4 3.5 366.1 2.6 588.9 10.2 1.0 691.9 975.8 CLDN9 ENSG00000213937 "Claudin 9" O95484 16 3012923-3014505 "Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.8;pituitary gland: 25.2" "Cell type enhanced" "Detected in some" "Cholangiocytes: 15.7;Ductal cells: 9.5;Endometrial ciliated cells: 8.6;Pancreatic endocrine cells: 8.1;Respiratory ciliated cells: 18.1" "Cancer enhanced" "Detected in many" "ovarian cancer: 10.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 4.7;CAPAN-2: 7.3;MCF7: 24.2;SCLC-21H: 20.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA076613 Supported "Vesicles,Cell Junctions" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "Cell Junctions" Vesicles "HPA076613: AB_2686808" "unprognostic (7.93e-2)" "unprognostic (1.40e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (2.24e-6)" "unprognostic (4.91e-2)" "unprognostic (6.04e-2)" "unprognostic (1.13e-1)" "unprognostic (2.75e-1)" "unprognostic (1.64e-2)" "unprognostic (5.06e-2)" "unprognostic (8.97e-3)" "unprognostic (4.51e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (1.29e-1)" "unprognostic (7.71e-3)" "unprognostic (5.55e-2)" 0.3 0.2 3.3 0.2 4.4 2.7 0.2 10.8 5.6 0.3 2.4 0.5 0.7 0.0 0.0 0.1 1.2 0.2 1.7 3.3 3.6 1.5 5.2 1.2 0.0 5.3 4.0 0.0 6.4 1.4 25.2 0.1 5.6 0.3 0.0 1.9 0.6 0.0 1.2 0.2 0.5 0.0 3.7 2.3 0.5 0.3 4.1 0.3 0.4 0.1 0.0 0.2 0.1 5.2 4.7 0.2 0.0 2.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 7.3 0.0 0.1 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.2 0.0 0.0 24.2 0.0 2.0 0.1 0.3 0.2 0.0 0.0 0.2 0.2 0.1 20.8 0.0 0.6 0.9 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.3 0.0 0.3 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.4 10.8 5.6 3.3 3.6 5.3 4.0 5.6 3.7 4.1 5.2 0.0 0.0 0.0 0.0 0.0 0.1 2.6 1.4 0.0 1.3 1.1 0.4 0.3 15.7 2.3 0.0 0.0 0.3 0.0 0.6 0.0 9.5 0.1 8.6 0.3 0.1 1.8 0.0 0.8 1.7 0.9 0.1 0.0 2.7 0.0 0.0 0.4 0.3 0.1 0.0 0.4 0.4 2.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 3.4 8.1 1.5 0.0 0.0 1.2 0.4 0.1 18.1 0.7 0.0 0.0 0.6 0.1 0.2 0.0 0.4 1.1 0.1 0.0 0.6 1.8 CLEC16A "Gop-1, KIAA0350" ENSG00000038532 "C-type lectin domain containing 16A" Q2KHT3 16 10944564-11182186 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 130.9;Early spermatids: 118.7;Excitatory neurons: 93.3;Inhibitory neurons: 135.1;Late spermatids: 84.8;Oligodendrocyte precursor cells: 69.4;Oligodendrocytes: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "HDLM-2: 110.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035814, HPA035815, HPA061385" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 43: Testis - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Vesicles" "HPA035814: AB_10600801, HPA035815: AB_10671937, HPA061385: AB_2684498" "unprognostic (3.41e-1)" "unprognostic (4.58e-2)" "unprognostic (7.36e-2)" "unprognostic (1.56e-2)" "unprognostic (3.44e-1)" "unprognostic (1.33e-2)" "unprognostic (3.44e-1)" "unprognostic (2.22e-3)" "unprognostic (4.54e-2)" "unprognostic (7.78e-3)" "unprognostic (2.08e-1)" "unprognostic (3.49e-1)" "prognostic favorable (2.92e-6)" "unprognostic (2.69e-1)" "unprognostic (1.79e-1)" "unprognostic (8.22e-2)" "unprognostic (3.03e-1)" 10.2 12.8 12.1 7.2 13.4 13.2 9.4 16.7 17.3 11.2 23.6 9.5 8.2 9.0 6.9 13.9 9.4 4.8 14.6 11.3 11.1 16.6 16.2 12.8 9.3 13.8 14.5 8.2 8.9 11.7 17.3 7.0 13.8 11.3 5.9 11.5 9.1 5.7 17.5 14.2 10.8 6.2 9.7 12.4 10.4 46.8 21.0 10.9 13.3 8.3 8.8 9.1 10.4 11.7 11.6 12.1 9.0 11.9 14.8 10.3 8.0 11.7 11.4 9.6 12.5 13.5 21.1 22.8 26.6 14.3 10.6 10.1 11.6 21.7 12.3 110.3 12.5 10.4 16.4 14.4 10.4 11.5 21.5 12.3 10.4 15.9 13.4 8.8 13.3 12.4 17.6 13.8 11.5 19.0 18.2 9.1 7.2 10.0 9.5 24.6 7.6 13.5 20.1 8.4 11.5 15.3 16.8 17.1 9.1 10.4 12.1 17.7 14.2 12.4 16.1 18.3 10.4 9.7 9.2 18.7 15.5 16.4 13.1 2.7 1.9 1.4 2.2 1.5 1.3 1.7 1.8 1.5 1.5 2.8 2.1 1.8 2.6 1.8 3.0 2.0 1.4 1.1 12.1 13.4 16.7 17.3 11.3 11.1 13.8 14.5 13.8 9.7 21.0 11.7 7.1 16.0 10.0 130.9 12.8 7.1 3.7 5.9 11.4 11.7 5.2 5.1 5.9 8.6 8.8 3.7 37.5 3.4 5.5 12.1 0.0 6.0 118.7 7.5 6.0 6.1 7.7 8.6 93.3 6.4 2.6 6.2 9.2 8.0 8.2 5.7 9.7 12.6 4.8 11.8 135.1 7.9 6.1 5.4 6.2 84.8 5.6 6.8 3.6 40.3 8.6 3.9 4.1 69.4 72.9 6.5 4.0 8.6 8.8 3.5 10.3 3.5 8.9 18.3 0.0 7.4 4.5 27.1 8.4 13.4 8.2 3.8 8.6 3.3 6.7 4.9 CLINT1 "CLINT, ENTH, EPNR, KIAA0171" ENSG00000113282 "Clathrin interactor 1" Q14677 5 157785743-157859145 "Plasma proteins, Predicted intracellular proteins, Transporters" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "basophil: 749.5" "Lineage enriched" "Detected in all" 10 "granulocytes: 749.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043280, HPA056947" Supported Supported Nucleoplasm,Vesicles NA NA 540000 "Cluster 46: Basophils - DNA binding" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Vesicles Nucleoplasm "HPA043280: AB_10793944, HPA056947: AB_2683283" "unprognostic (1.92e-2)" "unprognostic (6.93e-2)" "prognostic favorable (2.95e-4)" "unprognostic (7.23e-2)" "unprognostic (1.55e-1)" "unprognostic (2.79e-1)" "unprognostic (2.53e-1)" "unprognostic (8.13e-2)" "unprognostic (1.05e-1)" "unprognostic (3.19e-2)" "unprognostic (4.89e-3)" "unprognostic (1.04e-1)" "prognostic favorable (8.88e-5)" "unprognostic (1.91e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (6.77e-4)" "unprognostic (3.56e-1)" 28.6 34.4 10.3 42.8 11.9 101.1 31.4 10.6 14.8 36.4 17.7 53.9 68.3 26.4 54.2 72.0 37.8 61.4 34.2 11.8 12.7 70.4 89.5 36.3 49.4 11.8 11.9 26.9 49.3 113.2 17.8 47.1 11.4 29.5 53.4 16.0 50.8 42.4 53.1 39.7 55.7 31.9 11.0 31.0 69.2 20.3 12.4 50.7 56.0 41.0 73.8 64.5 38.8 11.4 65.6 91.7 64.3 59.8 86.3 71.0 91.6 89.7 87.5 83.4 115.9 128.7 100.0 121.3 100.3 82.6 112.0 95.8 87.1 100.4 120.7 57.9 70.4 80.6 80.4 65.2 85.5 112.9 105.6 52.5 75.6 94.7 105.6 53.6 80.0 69.6 70.6 66.1 69.9 56.7 88.7 60.5 67.8 63.6 93.9 78.8 96.9 103.0 84.8 115.4 56.6 62.1 64.5 111.7 87.4 81.2 76.4 78.0 83.7 74.6 56.3 69.5 89.4 76.1 77.9 154.4 61.0 126.2 67.5 749.5 46.5 179.7 43.6 49.2 75.2 47.5 41.4 43.7 62.7 46.2 35.9 38.8 17.6 58.6 53.4 48.5 66.2 53.1 10.3 11.9 10.6 14.8 11.8 12.7 11.8 11.9 11.4 11.0 12.4 11.4 68.6 60.9 132.9 25.1 76.0 57.1 83.7 69.4 80.2 21.6 74.4 44.2 103.9 105.8 137.8 68.0 8.4 45.1 73.8 73.5 95.9 93.4 4.1 116.5 82.4 52.8 54.5 54.9 31.9 64.0 71.9 71.8 119.3 141.9 84.7 40.2 21.0 86.8 30.5 11.8 29.0 78.9 38.7 42.9 87.8 5.6 47.2 73.0 35.6 28.1 94.1 25.5 73.2 39.2 31.4 53.7 62.6 28.6 158.3 92.5 50.3 94.5 148.5 19.0 39.5 67.2 61.9 44.2 40.2 156.3 78.3 68.3 65.5 82.0 99.0 271.5 CLIP4 "FLJ21069, RSNL2" ENSG00000115295 "CAP-Gly domain containing linker protein family member 4" Q8N3C7 2 29097705-29189643 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 169.2;Inhibitory neurons: 142.8;Oligodendrocyte precursor cells: 130.2;Oligodendrocytes: 247.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 25.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 83.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043366, HPA056246" Uncertain Enhanced Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA043366: AB_10963051, HPA056246: AB_2683078" "unprognostic (1.97e-2)" "unprognostic (1.49e-2)" "unprognostic (2.14e-2)" "unprognostic (2.47e-3)" "unprognostic (3.64e-1)" "unprognostic (6.82e-2)" "unprognostic (1.15e-2)" "unprognostic (8.82e-3)" "unprognostic (3.62e-1)" "unprognostic (4.32e-2)" "unprognostic (2.73e-1)" "unprognostic (7.99e-2)" "prognostic unfavorable (1.83e-4)" "unprognostic (3.59e-3)" "unprognostic (6.35e-2)" "unprognostic (2.14e-1)" "unprognostic (1.99e-2)" 19.3 9.8 15.1 9.5 24.7 1.9 14.2 20.6 19.7 14.3 18.3 20.8 4.8 13.7 8.7 23.4 15.5 13.4 30.0 15.2 18.9 9.0 4.5 18.7 10.2 20.6 21.8 22.7 6.3 14.3 20.0 16.4 20.9 16.6 7.0 17.9 13.9 15.2 71.9 30.9 10.7 18.6 18.6 10.0 10.2 17.5 18.1 13.5 33.5 43.8 10.7 20.8 19.9 31.4 82.3 22.6 3.4 12.1 31.4 47.0 0.1 31.8 54.4 17.5 19.9 0.7 52.7 10.2 15.9 55.1 69.9 33.0 3.6 24.7 24.8 18.9 5.4 0.0 29.1 1.2 79.7 0.0 16.2 33.3 61.3 23.2 83.8 62.8 12.4 7.4 0.5 31.5 26.7 0.6 7.9 3.6 0.9 4.8 5.0 0.1 20.1 1.6 32.0 14.4 5.3 13.7 27.6 11.2 29.0 3.3 0.0 4.9 39.4 4.1 31.6 13.7 13.8 16.2 0.1 0.1 19.0 0.0 12.7 2.5 6.1 0.2 7.9 14.8 12.4 1.4 6.1 8.4 2.4 0.5 6.9 6.8 1.2 5.6 25.9 0.0 2.3 5.6 15.1 24.7 20.6 19.7 15.2 18.9 20.6 21.8 20.9 18.6 18.1 31.4 0.9 64.1 15.0 78.7 7.2 17.1 27.6 26.8 30.1 31.0 11.4 8.9 76.2 0.0 18.5 12.9 29.2 6.7 18.6 0.1 3.9 10.7 169.2 16.1 8.4 2.5 0.0 2.5 75.1 9.1 1.7 26.5 4.1 12.9 5.1 13.1 1.4 1.8 9.9 20.2 142.8 0.0 8.2 36.1 6.0 91.1 27.4 25.9 8.8 15.9 17.5 18.7 19.6 130.2 247.2 22.1 0.0 24.0 30.9 25.8 0.0 5.9 32.1 17.9 13.1 24.2 9.2 9.4 1.6 29.7 27.3 21.5 21.9 16.4 0.2 24.2 CLN6 "FLJ20561, HsT18960, nclf" ENSG00000128973 "CLN6 transmembrane ER protein" Q9NWW5 15 68206992-68257211 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 181.8;Hofbauer cells: 88.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066046, HPA066759" Approved Approved "Nucleoli,Endoplasmic reticulum,Vesicles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 20: HeLa - Mitochondria" "Cluster 56: Bipolar cells - Visual perception" "Endoplasmic reticulum" "Nucleoli, Vesicles" "HPA066046: AB_2685604, HPA066759: " "unprognostic (1.01e-1)" "unprognostic (1.54e-3)" "unprognostic (7.01e-2)" "unprognostic (3.58e-2)" "unprognostic (2.71e-2)" "unprognostic (3.08e-1)" "unprognostic (2.24e-2)" "unprognostic (5.07e-2)" "unprognostic (2.40e-2)" "unprognostic (2.11e-1)" "unprognostic (1.69e-1)" "unprognostic (1.85e-1)" "prognostic favorable (4.87e-4)" "unprognostic (1.22e-2)" "unprognostic (2.22e-1)" "unprognostic (2.49e-1)" "unprognostic (6.78e-2)" 11.6 17.6 12.7 14.8 13.0 29.9 11.5 13.3 14.9 11.0 13.2 17.5 14.6 9.8 6.8 16.9 9.8 9.6 9.3 12.1 12.6 20.0 22.7 13.2 16.2 13.3 13.1 6.8 19.1 10.4 10.1 11.6 13.8 12.4 14.9 11.8 14.8 9.2 17.0 14.7 14.6 10.4 12.8 20.7 13.3 10.9 13.0 11.6 12.9 7.3 16.7 10.7 9.6 14.5 38.2 93.1 23.9 33.9 14.5 11.8 57.1 35.3 17.0 42.8 34.9 72.1 60.5 57.6 17.2 21.4 31.7 69.5 69.8 34.5 17.0 38.5 82.3 84.3 66.1 54.3 29.7 95.6 58.1 20.8 11.4 34.7 23.7 9.0 29.1 33.1 56.9 116.0 33.6 103.8 44.0 69.4 57.1 67.3 38.3 42.1 71.8 80.6 36.2 97.0 48.2 20.0 39.5 61.7 34.3 18.0 33.1 95.5 19.3 48.1 55.7 35.8 127.2 81.3 97.3 47.4 30.0 115.4 47.6 0.0 8.8 0.6 3.0 13.0 4.0 2.9 2.2 4.3 5.2 2.3 2.8 1.3 10.5 2.0 16.1 4.4 2.3 3.5 12.7 13.0 13.3 14.9 12.1 12.6 13.3 13.1 13.8 12.8 13.0 14.5 1.4 9.6 6.9 7.2 13.4 20.1 22.0 13.9 14.8 181.8 2.0 1.9 27.4 10.0 9.6 5.5 16.7 42.8 7.1 22.7 0.0 3.3 0.4 1.0 4.8 9.7 15.1 32.8 8.9 1.8 58.4 9.1 8.2 1.4 8.9 5.6 11.0 21.9 88.4 21.9 8.1 20.5 16.2 24.2 14.0 1.4 9.0 11.3 19.6 8.4 12.9 16.9 11.3 5.0 10.2 3.6 26.0 8.2 33.4 23.7 15.6 2.1 3.3 32.7 6.6 7.5 5.6 1.0 19.5 21.1 14.1 21.8 9.5 5.3 35.6 16.3 CLNK MIST ENSG00000109684 "Cytokine dependent hematopoietic cell linker" Q7Z7G1 4 10486395-10684768 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 6.2" "Cell type enriched" "Detected in many" 5 "Ionocytes: 73.2" "Cancer enriched" "Detected in single" 13 "renal cancer: 3.3" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "HDLM-2: 4.1;U-937: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035671, HPA035672" Uncertain Uncertain Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA035671: AB_10669673, HPA035672: AB_10669775" "unprognostic (2.47e-3)" "unprognostic (4.74e-4)" "unprognostic (1.99e-4)" "unprognostic (2.24e-3)" "unprognostic (1.17e-1)" "unprognostic (2.23e-6)" "unprognostic (2.05e-2)" "unprognostic (5.37e-4)" "unprognostic (9.87e-2)" "unprognostic (3.75e-2)" "unprognostic (2.55e-1)" "unprognostic (7.74e-3)" "unprognostic (1.55e-1)" "unprognostic (6.05e-3)" "unprognostic (6.65e-3)" "unprognostic (1.45e-1)" "unprognostic (2.99e-2)" 0.3 0.2 0.5 0.9 0.4 0.4 0.6 1.5 0.7 0.2 0.5 0.3 0.6 0.4 1.2 0.4 0.2 0.5 0.2 0.5 0.5 6.2 0.9 0.6 3.0 0.4 0.2 0.4 0.1 0.1 1.3 1.0 0.5 0.4 0.4 0.3 0.5 0.3 0.2 0.8 0.9 0.1 0.1 1.5 1.1 0.8 0.5 1.4 0.3 0.0 2.0 0.3 0.0 0.9 0.0 0.2 0.2 0.1 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 4.1 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.2 0.3 0.0 0.1 0.2 0.1 0.1 0.1 0.0 0.4 0.0 0.1 0.2 0.1 0.2 0.0 0.1 0.2 2.2 0.1 0.5 0.1 0.2 0.2 0.1 0.1 1.4 0.4 0.1 2.6 1.1 0.1 0.1 0.4 2.0 0.0 0.6 1.8 0.2 0.5 0.4 1.5 0.7 0.5 0.5 0.4 0.2 0.5 0.1 0.5 0.9 0.1 3.2 3.0 1.0 12.9 0.8 0.8 0.0 0.0 1.3 0.3 0.3 0.7 0.0 0.9 0.0 2.1 0.3 4.6 0.1 13.7 0.0 5.3 0.7 0.2 0.4 0.0 5.3 1.7 0.0 2.2 0.5 0.5 0.9 11.4 0.2 0.7 0.3 0.3 0.0 1.6 0.2 73.2 1.9 5.5 5.4 0.3 3.5 1.8 1.9 0.5 0.4 0.0 1.0 0.7 0.1 0.0 2.2 1.1 0.7 0.0 0.2 0.2 1.0 0.0 1.1 0.5 1.9 0.8 0.0 0.4 0.1 6.0 1.3 0.0 0.7 CLOCK "bHLHe8, KAT13D, KIAA0334" ENSG00000134852 "Clock circadian regulator" O15516 4 55427903-55546909 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, Transcription, Transcription regulation" "Activator, Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001867, HPA027565" Supported Enhanced Nucleoplasm,Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Nucleoplasm Vesicles "HPA001867: AB_1078537, HPA027565: AB_1846975" "unprognostic (1.30e-2)" "unprognostic (9.02e-2)" "unprognostic (4.25e-3)" "unprognostic (2.48e-1)" "unprognostic (3.94e-2)" "unprognostic (2.00e-2)" "unprognostic (1.17e-1)" "unprognostic (1.30e-1)" "unprognostic (4.52e-2)" "unprognostic (4.32e-2)" "unprognostic (3.01e-2)" "unprognostic (5.96e-2)" "unprognostic (4.07e-2)" "unprognostic (8.31e-2)" "unprognostic (1.69e-1)" "unprognostic (5.18e-2)" "unprognostic (7.16e-2)" 5.5 6.1 3.7 4.2 4.2 1.3 5.9 8.9 5.4 8.0 5.5 5.1 4.9 6.9 5.7 9.2 5.3 4.3 7.5 4.7 5.3 6.5 5.5 4.6 2.9 2.8 3.7 6.2 5.1 10.3 5.5 5.5 3.3 6.2 5.7 11.6 4.6 6.1 9.8 6.8 5.6 7.1 3.8 4.5 6.9 14.1 3.8 3.0 10.1 9.2 3.7 5.6 6.8 5.0 20.0 9.1 7.5 11.6 11.8 11.5 3.6 18.7 16.4 12.9 12.7 5.1 14.8 5.1 9.9 22.8 10.3 15.9 9.5 15.4 23.2 6.9 3.1 4.4 9.4 6.7 10.3 7.0 4.7 6.7 15.8 18.8 18.7 10.4 13.1 4.6 10.1 10.1 21.3 10.6 4.0 4.1 5.0 16.3 9.4 2.5 8.7 3.3 11.0 10.9 7.6 6.2 13.5 16.7 8.9 6.2 5.7 4.2 17.1 18.4 19.5 6.0 26.6 9.1 7.5 3.1 15.6 5.8 14.6 0.0 0.7 0.2 0.7 0.7 1.3 0.4 0.9 0.8 1.1 0.7 0.4 0.6 0.2 0.9 0.7 0.5 0.9 0.4 3.7 4.2 8.9 5.4 4.7 5.3 2.8 3.7 3.3 3.8 3.8 5.0 32.2 41.7 27.7 49.3 15.2 31.1 21.8 28.5 27.9 63.4 21.5 14.9 55.2 14.3 27.4 14.7 43.8 11.3 11.9 21.5 1.9 13.6 34.5 34.2 39.9 32.1 39.7 3.8 95.9 16.5 6.8 28.0 25.0 32.0 3.8 16.6 28.9 27.7 11.6 33.7 114.6 18.5 18.3 17.0 26.1 16.9 23.9 16.9 10.6 70.3 14.0 26.7 19.6 82.0 93.1 28.3 13.2 36.1 18.5 34.0 29.6 19.7 25.2 41.4 13.1 36.5 28.2 64.9 72.5 55.1 37.5 5.2 14.0 21.7 15.6 51.6 CLSTN2 "CDHR13, CS2, CSTN2, FLJ39113" ENSG00000158258 "Calsyntenin 2" Q9H4D0 3 139935185-140577397 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 18.2;brain: 26.7;ovary: 64.7" "Cell type enriched" "Detected in many" 4 "Excitatory neurons: 552.2" "Cancer enriched" "Detected in many" 7 "breast cancer: 15.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 32.7;SCLC-21H: 14.5;SuSa: 42.7;THP-1: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031342, HPA061800" Approved Uncertain "Vesicles,Cytokinetic bridge" Yes No 130000 "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "Cytokinetic bridge" "HPA031342: AB_10602800, HPA061800: AB_2684615" "unprognostic (7.58e-2)" "unprognostic (2.64e-2)" "unprognostic (8.02e-2)" "unprognostic (1.51e-3)" "unprognostic (5.52e-3)" "unprognostic (8.35e-2)" "unprognostic (1.58e-1)" "unprognostic (1.21e-1)" "unprognostic (5.58e-1)" "unprognostic (6.25e-2)" "unprognostic (2.24e-1)" "unprognostic (1.81e-1)" "unprognostic (1.71e-1)" "unprognostic (2.52e-2)" "unprognostic (3.16e-2)" "unprognostic (7.63e-5)" "unprognostic (7.22e-5)" 18.2 4.8 17.3 0.3 15.3 0.0 8.8 0.0 26.7 4.2 0.0 1.4 0.5 5.1 0.7 1.0 4.7 2.1 6.1 23.4 0.0 4.3 0.8 1.1 2.7 13.3 3.1 64.7 1.6 0.8 0.9 0.9 9.1 5.3 0.8 2.7 1.3 1.1 1.6 2.0 1.3 6.8 0.0 0.1 1.0 0.6 0.0 0.7 2.8 2.2 0.2 1.6 3.2 15.6 0.0 0.0 5.1 0.0 2.2 0.6 0.0 0.7 0.0 0.0 0.0 2.9 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 1.8 0.3 0.0 0.0 0.0 0.0 0.0 0.1 2.5 0.0 0.1 0.0 32.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 2.1 0.0 0.0 0.0 42.7 2.2 9.4 0.0 1.0 0.5 1.4 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 15.3 0.0 26.7 23.4 0.0 13.3 3.1 9.1 0.0 0.0 15.6 2.1 0.0 0.0 18.3 0.0 0.5 0.3 0.0 8.6 1.8 10.9 2.2 8.0 0.0 0.6 3.7 0.0 0.2 0.1 0.0 1.9 0.2 39.8 0.5 8.9 0.8 0.0 0.0 552.2 0.2 0.0 9.1 0.0 0.2 0.0 25.0 2.2 0.0 0.1 0.0 111.5 0.0 0.0 0.3 1.5 31.1 28.0 0.8 0.0 5.6 0.0 0.8 0.0 108.6 29.4 0.0 0.0 0.7 0.0 5.0 0.0 32.3 3.0 3.8 0.0 28.3 13.7 0.8 0.8 0.4 0.0 0.0 0.7 0.5 0.0 0.3 CLTA Lca ENSG00000122705 "Clathrin light chain A" P09496 9 36190856-36304781 "Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 1299.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002665, HPA050918, HPA054667" Enhanced Enhanced Vesicles,Endosomes,Lysosomes NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Vesicles, Endosomes, Lysosomes" "CAB002665: , HPA050918: AB_2681273, HPA054667: AB_2682565" "prognostic favorable (5.64e-4)" "unprognostic (7.62e-2)" "unprognostic (9.22e-2)" "unprognostic (8.45e-3)" "unprognostic (1.71e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (9.46e-5)" "unprognostic (1.42e-1)" "unprognostic (1.01e-1)" "unprognostic (1.92e-3)" "unprognostic (7.27e-2)" "unprognostic (2.15e-1)" "unprognostic (1.23e-3)" "unprognostic (5.92e-2)" "unprognostic (1.56e-1)" "prognostic favorable (1.01e-4)" "unprognostic (4.98e-2)" 172.8 174.2 131.6 80.8 139.1 67.2 165.6 144.7 165.1 170.9 137.5 163.3 107.9 165.6 100.7 207.1 158.9 64.4 98.1 133.3 143.8 236.0 146.8 146.2 84.1 145.1 138.5 205.6 164.3 104.3 139.3 124.4 151.4 145.0 108.6 84.8 162.8 71.2 87.7 163.2 136.0 84.9 141.6 153.0 161.4 108.5 141.7 85.2 160.1 51.5 93.4 150.9 158.4 151.5 326.3 257.2 188.4 146.3 270.0 269.8 302.6 328.5 248.2 258.1 301.5 194.2 143.9 243.8 177.0 220.9 460.7 136.2 238.8 228.2 238.4 166.0 193.1 187.5 255.0 199.8 359.4 201.0 166.5 297.3 250.5 297.4 234.3 241.0 329.6 129.3 166.0 126.4 399.0 113.3 182.2 254.8 301.8 218.8 360.3 173.3 124.8 142.1 353.7 229.1 146.1 245.3 137.3 160.0 289.4 220.2 146.9 244.2 418.4 209.4 234.0 240.3 347.9 83.0 208.9 259.5 256.9 278.0 188.9 142.2 221.7 115.4 97.1 239.6 101.9 121.0 104.9 100.2 222.6 119.6 92.9 82.0 86.7 96.2 191.8 192.2 162.9 209.4 131.6 139.1 144.7 165.1 133.3 143.8 145.1 138.5 151.4 141.6 141.7 151.5 291.5 128.2 143.9 14.4 105.9 197.3 274.3 374.3 169.0 139.4 274.0 315.0 51.5 217.3 247.4 180.3 60.5 958.0 140.1 349.3 463.7 480.5 51.9 241.5 174.3 244.0 183.8 154.8 28.5 335.6 469.1 187.5 142.2 182.7 73.5 198.4 312.7 170.6 903.7 92.5 30.4 350.5 248.2 391.7 172.0 97.6 262.9 249.3 195.7 20.6 343.5 282.8 117.4 16.1 49.0 465.2 426.4 215.5 97.7 320.5 411.5 651.7 304.7 127.3 177.5 170.0 310.4 288.0 216.8 210.9 193.2 1299.5 103.7 281.6 380.0 360.4 CLTB Lcb ENSG00000175416 "Clathrin light chain B" P09497 5 176392501-176416539 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 1839.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 704.2;MCF7: 641.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003692, HPA036458" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "Plasma membrane, Cytosol" "CAB003692: AB_425372, HPA036458: AB_2675136" "unprognostic (1.09e-1)" "unprognostic (1.73e-1)" "unprognostic (4.51e-2)" "unprognostic (1.46e-1)" "unprognostic (1.34e-2)" "unprognostic (1.60e-1)" "unprognostic (3.54e-3)" "unprognostic (1.83e-2)" "unprognostic (1.74e-2)" "unprognostic (1.93e-1)" "unprognostic (7.42e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (7.89e-5)" "unprognostic (3.55e-1)" "unprognostic (7.50e-2)" "unprognostic (8.59e-2)" "unprognostic (1.60e-2)" 102.9 133.6 125.8 50.1 125.1 40.6 82.9 117.8 176.7 180.4 125.3 133.9 92.3 85.9 23.2 473.7 82.4 34.1 320.8 130.8 129.6 90.4 82.5 96.5 32.9 136.9 122.8 107.2 68.2 70.1 112.8 57.5 138.1 88.1 45.5 37.9 128.6 44.4 322.5 453.1 99.7 41.2 114.5 68.7 123.3 38.9 127.9 43.7 69.5 120.8 58.5 106.2 300.8 133.6 229.1 107.6 29.9 128.2 65.7 49.2 244.4 286.3 110.9 178.6 127.0 140.3 103.9 49.6 165.0 130.2 71.8 213.3 51.4 704.2 69.7 341.7 95.3 33.6 163.3 87.7 102.9 53.2 85.6 52.6 241.5 98.1 114.7 36.0 84.7 39.2 65.2 123.4 100.3 641.9 84.5 81.1 24.4 189.5 158.2 91.3 52.9 165.2 95.6 92.0 127.7 43.7 136.6 148.0 103.6 34.7 61.4 101.9 185.2 64.0 96.3 117.5 165.1 96.5 73.3 68.5 51.4 112.7 74.4 6.6 19.7 61.7 13.6 15.8 7.0 5.9 11.9 13.2 20.0 10.1 10.0 10.0 36.6 15.0 20.8 16.1 24.9 8.1 125.8 125.1 117.8 176.7 130.8 129.6 136.9 122.8 138.1 114.5 127.9 133.6 113.7 57.7 19.8 8.5 54.7 634.0 238.7 155.7 180.4 310.5 105.5 124.6 208.5 72.9 93.4 82.8 64.6 141.1 82.3 794.5 135.0 324.7 9.5 58.4 72.7 102.2 151.8 43.6 25.4 453.1 586.9 136.7 193.2 85.2 48.2 40.8 70.3 96.3 111.9 336.5 24.1 348.5 114.0 80.7 226.1 13.7 122.1 88.4 220.5 6.5 85.7 136.1 107.1 8.0 15.2 1839.9 786.9 129.8 76.4 391.4 545.7 269.7 49.6 64.3 78.9 79.6 161.4 15.9 29.1 415.6 803.0 386.5 81.3 151.2 289.7 436.0 CLTC "CLTCL2, Hc" ENSG00000141367 "Clathrin heavy chain" Q00610 17 59619689-59696956 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Cell cycle, Cell division, Mitosis" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010389, CAB011571, CAB017155, HPA059143" Approved Enhanced "Vesicles,Endosomes,Lysosomes,Mitotic spindle,Cytosol" Yes No 14000000 "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Vesicles, Endosomes, Lysosomes" "Mitotic spindle, Cytosol" "CAB010389: AB_2083184, CAB011571: AB_2083165, CAB017155: , HPA059143: AB_2683924" "unprognostic (1.56e-1)" "prognostic unfavorable (7.35e-4)" "prognostic favorable (7.65e-4)" "unprognostic (1.03e-1)" "unprognostic (2.62e-1)" "unprognostic (5.23e-3)" "prognostic unfavorable (5.54e-4)" "unprognostic (1.11e-1)" "unprognostic (6.43e-2)" "unprognostic (1.09e-1)" "unprognostic (3.34e-2)" "unprognostic (2.69e-1)" "unprognostic (1.49e-1)" "unprognostic (1.18e-1)" "unprognostic (9.22e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (2.02e-4)" 105.4 95.2 42.1 89.7 54.9 96.3 81.6 67.3 103.9 92.3 36.7 121.7 74.1 83.1 126.4 82.1 67.8 88.9 90.7 60.7 65.1 125.5 117.7 82.1 75.5 95.5 52.4 73.2 56.8 186.8 51.6 139.6 95.2 97.8 128.3 163.6 68.6 104.2 88.4 81.3 73.3 121.0 43.8 78.8 91.2 71.3 68.2 76.0 114.1 83.9 86.8 101.1 51.6 55.0 293.3 426.1 207.6 207.0 345.8 280.5 240.0 305.7 321.7 268.2 278.9 264.7 175.2 200.6 340.1 436.4 296.9 186.2 313.6 255.1 356.2 214.4 166.8 328.2 248.8 414.0 262.3 228.5 182.3 266.9 154.6 408.0 262.3 211.4 302.0 99.9 334.4 280.4 429.1 511.1 135.6 65.1 179.6 263.3 248.2 118.7 343.6 244.9 297.5 404.1 184.1 216.7 188.3 122.9 180.4 270.5 290.3 142.3 385.6 492.4 287.9 237.0 317.8 213.3 320.3 181.4 357.7 151.6 305.3 16.6 33.1 21.3 17.5 36.3 21.7 13.7 16.1 19.2 36.5 12.9 13.4 15.0 19.9 18.9 32.5 22.8 22.1 23.3 42.1 54.9 67.3 103.9 60.7 65.1 95.5 52.4 95.2 43.8 68.2 55.0 62.6 99.3 107.9 80.3 46.3 63.9 44.4 75.6 28.5 91.9 58.5 34.7 77.9 71.4 103.3 77.3 60.5 109.1 60.7 184.0 27.4 76.2 23.3 95.5 95.6 79.7 120.6 115.9 137.7 97.7 47.7 84.5 99.4 106.1 68.4 75.5 120.7 185.4 182.5 85.8 135.9 120.7 77.3 195.0 93.2 77.2 74.0 128.3 53.4 79.6 102.8 53.9 38.1 73.4 124.2 106.2 76.1 93.6 83.0 86.3 102.7 132.4 128.0 65.2 78.9 66.0 82.8 52.7 38.0 60.5 79.3 107.9 45.9 81.3 127.8 91.6 CLTCL1 "CHC22, CLH22, CLTCL, CLTD" ENSG00000070371 "Clathrin heavy chain like 1" P53675 22 19179473-19291719 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 187.4;testis: 47.2;tongue: 61.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 11.3;Cone photoreceptor cells: 14.6;Early spermatids: 19.3;Late spermatids: 17.0;Oligodendrocyte precursor cells: 12.5;Oligodendrocytes: 12.5;Spermatocytes: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 2.1;neutrophil: 5.2" "Group enriched" "Detected in many" 20 "granulocytes: 5.2;monocytes: 2.1" "Cell line enhanced" "Detected in many" "HMC-1: 64.8;K-562: 31.8" "HPA075327, HPA075795" Enhanced Approved Vesicles NA NA 2300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA075327: , HPA075795: AB_2686764" "unprognostic (1.29e-2)" "unprognostic (3.13e-2)" "unprognostic (1.93e-2)" "unprognostic (3.16e-3)" "unprognostic (8.20e-2)" "unprognostic (6.93e-3)" "unprognostic (1.60e-1)" "unprognostic (3.28e-1)" "unprognostic (4.42e-2)" "unprognostic (2.93e-3)" "unprognostic (3.14e-1)" "unprognostic (1.02e-1)" "unprognostic (1.20e-1)" "unprognostic (8.71e-4)" "unprognostic (1.61e-1)" "unprognostic (2.10e-2)" "unprognostic (1.06e-1)" 6.8 16.0 5.4 0.8 6.1 15.6 4.8 6.2 6.5 5.0 5.0 2.4 0.5 3.1 1.6 3.6 3.8 1.2 14.8 5.2 7.8 3.2 6.5 3.0 0.7 7.4 8.6 3.6 2.5 2.1 13.4 1.5 8.5 5.2 1.0 2.0 3.9 0.8 187.4 4.1 1.8 1.7 5.7 3.5 2.8 47.2 9.1 3.9 8.0 61.3 0.5 2.8 3.7 6.9 4.5 4.6 3.0 4.9 10.8 5.9 1.4 3.1 3.3 4.2 6.3 1.7 1.4 1.9 0.4 7.0 3.3 1.5 4.7 8.5 3.5 0.3 4.6 0.2 4.4 5.3 5.5 6.5 64.8 25.0 7.0 7.8 10.9 12.5 2.7 2.4 31.8 1.7 10.0 3.6 0.6 22.4 3.8 18.1 2.8 2.4 24.2 0.1 3.4 1.8 6.9 1.2 6.6 4.1 0.4 3.6 8.9 27.1 0.8 7.6 15.5 4.2 5.2 3.1 8.4 0.8 4.5 17.4 1.6 0.0 2.1 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 5.2 0.0 0.0 0.0 0.0 0.4 5.4 6.1 6.2 6.5 5.2 7.8 7.4 8.6 8.5 5.7 9.1 6.9 1.4 3.2 0.5 9.4 0.1 0.6 0.5 1.0 1.2 2.4 0.7 0.3 11.3 1.5 1.8 0.0 14.6 0.4 0.2 1.2 0.0 0.8 19.3 1.2 1.9 0.9 0.0 0.8 4.5 0.0 0.2 1.4 1.5 1.4 0.0 3.5 1.1 2.4 0.3 0.0 8.9 1.3 6.1 1.0 0.7 17.0 2.5 0.5 0.0 4.7 1.3 1.5 0.0 12.5 12.5 1.2 0.8 4.1 0.1 1.3 0.2 1.3 1.0 2.0 0.0 2.6 4.5 14.5 4.7 1.0 0.9 1.1 0.1 6.2 0.9 0.0 CLTRN "NX17, TMEM27" ENSG00000147003 "Collectrin, amino acid transport regulator" Q9HBJ8 X 15627318-15675012 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "kidney: 486.4" "Cell type enriched" "Detected in some" 16 "Proximal tubular cells: 885.4" "Cancer enriched" "Detected in many" 35 "renal cancer: 106.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 8.5;hTERT-HME1: 5.2;RPTEC TERT1: 8.5;SuSa: 5.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA048543 Enhanced Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Endoplasmic reticulum, Vesicles" "HPA048543: AB_2680436" "unprognostic (1.27e-1)" "unprognostic (4.77e-2)" "unprognostic (2.45e-2)" "unprognostic (2.66e-2)" "unprognostic (5.20e-2)" "unprognostic (5.23e-2)" "unprognostic (1.25e-1)" "unprognostic (8.50e-2)" "unprognostic (1.90e-2)" "prognostic favorable (5.65e-4)" "unprognostic (1.05e-2)" "unprognostic (3.03e-1)" "prognostic favorable (6.78e-9)" "unprognostic (1.77e-1)" "unprognostic (2.60e-2)" "unprognostic (2.58e-1)" "unprognostic (1.33e-2)" 0.5 0.8 0.5 0.0 0.6 0.3 2.0 0.7 0.8 1.0 16.6 0.6 1.3 1.5 3.1 0.6 2.4 3.7 1.1 0.7 0.6 486.4 61.5 1.7 0.4 0.6 0.5 3.2 5.3 10.5 0.6 0.5 0.6 1.5 0.3 1.2 0.8 1.3 0.1 1.2 0.4 0.4 0.4 0.2 10.9 1.0 0.5 0.8 4.1 0.1 0.3 0.8 0.4 0.9 2.3 1.8 1.1 0.3 0.7 1.0 0.7 0.0 0.0 0.1 0.1 0.1 0.5 0.1 1.6 0.2 0.2 8.5 0.7 2.3 0.0 0.3 0.7 0.2 0.0 0.8 1.0 0.0 0.0 0.2 2.0 0.3 5.2 0.6 0.0 2.1 0.5 0.4 0.2 2.8 0.1 0.3 2.9 0.8 2.6 0.2 0.3 0.9 8.5 0.1 1.1 1.0 0.6 0.1 1.8 5.1 0.6 0.2 0.0 0.2 0.4 0.3 0.0 0.4 0.2 0.3 0.6 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.2 0.1 0.1 0.2 0.6 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.6 0.7 0.8 0.7 0.6 0.6 0.5 0.6 0.4 0.5 0.9 0.1 0.0 4.1 0.0 5.7 0.0 0.0 0.0 0.0 0.0 3.0 3.2 0.0 0.0 1.8 27.6 0.0 2.1 0.0 0.0 54.8 25.1 0.0 2.8 0.6 0.1 0.0 0.0 0.0 0.6 0.5 0.3 0.0 3.3 0.0 1.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 885.4 2.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.0 3.7 0.5 0.0 0.0 CLUAP1 "CFAP22, FAP22, FLJ13297, IFT38, KIAA0643" ENSG00000103351 "Clusterin associated protein 1" Q96AJ1 16 3500976-3539048 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 215.5;Endometrial ciliated cells: 119.2;Respiratory ciliated cells: 181.3;Rod photoreceptor cells: 116.8;Spermatocytes: 150.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036976, HPA044191" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm Vesicles "HPA036976: AB_10602209, HPA044191: AB_2678852" "unprognostic (1.78e-1)" "unprognostic (9.28e-3)" "unprognostic (1.21e-1)" "prognostic favorable (3.01e-4)" "unprognostic (1.57e-1)" "unprognostic (3.67e-1)" "unprognostic (4.53e-2)" "unprognostic (3.63e-2)" "unprognostic (2.04e-1)" "unprognostic (8.44e-2)" "unprognostic (3.13e-1)" "unprognostic (6.94e-3)" "unprognostic (5.11e-3)" "unprognostic (8.43e-2)" "unprognostic (2.07e-1)" "unprognostic (8.94e-3)" "unprognostic (1.12e-2)" 9.7 10.7 11.1 5.9 12.6 3.9 14.7 14.2 14.5 21.1 17.8 11.0 4.2 24.2 16.0 11.1 31.8 10.6 11.4 11.2 11.6 18.6 7.7 12.1 7.4 10.4 12.7 24.6 12.2 31.4 11.7 10.6 9.1 17.0 9.8 28.9 9.1 19.9 9.9 5.6 5.4 20.2 9.8 6.6 9.0 40.0 12.0 12.4 22.0 11.6 6.0 10.8 7.8 10.4 15.7 18.3 20.8 28.9 31.4 32.0 11.0 19.9 26.7 31.4 23.7 5.1 31.3 8.2 16.5 33.7 18.8 16.8 14.7 23.6 26.2 6.6 13.1 6.9 10.3 10.5 36.7 12.5 7.2 21.1 25.4 29.1 29.4 33.1 17.2 16.4 21.7 1.0 23.6 19.3 12.0 14.0 21.5 6.6 11.1 25.9 14.3 15.7 45.7 4.9 23.2 19.8 11.6 8.8 14.3 16.0 18.7 28.8 11.5 20.8 13.8 17.1 15.0 12.8 10.9 2.2 8.0 7.3 15.3 6.2 3.6 1.2 6.2 4.2 12.1 7.3 17.8 10.8 6.8 6.1 26.9 18.4 1.3 9.0 2.4 6.6 10.3 5.8 11.1 12.6 14.2 14.5 11.2 11.6 10.4 12.7 9.1 9.8 12.0 10.4 14.5 22.4 20.5 17.0 3.5 5.6 12.3 29.1 14.8 41.0 13.4 13.8 11.7 11.5 30.6 14.7 108.4 20.7 7.5 3.3 43.0 24.3 215.5 119.2 49.7 12.4 17.5 4.6 23.6 8.0 7.7 21.9 6.6 26.4 5.1 28.1 13.6 9.2 10.4 38.7 26.3 7.9 18.3 4.9 5.7 63.4 31.4 5.0 3.6 5.6 18.1 40.7 12.3 11.1 10.3 8.6 5.3 33.1 3.5 9.4 5.3 34.6 181.3 116.8 6.6 24.7 22.7 150.0 58.4 6.4 4.1 9.3 12.1 36.7 9.0 6.5 CLUH "CLU1, KIAA0664" ENSG00000132361 "Clustered mitochondria homolog" O75153 17 2689386-2712663 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 122.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "CACO-2: 266.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031505, HPA044346" Uncertain Supported "Nuclear bodies,Vesicles" NA NA 5500 "Cluster 7: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Nuclear bodies" "HPA031505: AB_2673912, HPA044346: AB_10962153" "unprognostic (3.48e-2)" "unprognostic (3.97e-2)" "unprognostic (9.02e-2)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (1.15e-2)" "unprognostic (2.85e-2)" "unprognostic (2.84e-2)" "unprognostic (1.84e-1)" "unprognostic (2.69e-2)" "unprognostic (5.64e-2)" "unprognostic (5.11e-2)" "prognostic favorable (1.92e-5)" "unprognostic (4.99e-2)" "unprognostic (1.25e-1)" "unprognostic (1.92e-2)" "unprognostic (6.26e-2)" 30.8 56.7 13.8 18.1 12.7 14.3 28.5 16.3 18.3 19.8 19.7 45.9 46.6 21.3 1.9 67.7 19.2 15.4 80.8 14.5 11.2 50.6 135.0 19.6 14.6 14.6 13.2 17.0 50.4 15.6 20.3 9.0 15.3 24.7 13.2 7.2 32.1 11.8 127.8 47.5 34.2 8.5 9.3 25.2 35.1 25.2 17.3 6.4 25.2 52.9 11.1 29.6 29.2 11.2 69.5 131.9 8.9 33.3 20.2 14.1 99.9 34.9 13.0 41.9 31.0 266.2 30.0 122.6 41.5 19.4 26.9 127.6 45.3 52.9 14.7 43.6 86.4 68.0 112.2 93.9 17.1 53.7 44.1 22.6 29.7 48.9 24.7 9.4 20.5 43.3 81.8 42.2 11.7 79.8 69.6 58.0 28.2 35.8 67.8 104.7 37.0 70.8 26.0 117.3 43.9 32.6 40.0 129.4 44.4 6.6 72.7 31.3 33.7 33.7 44.9 92.2 80.5 18.2 22.9 49.7 35.4 73.2 41.6 0.0 2.2 0.0 1.7 3.1 1.3 2.2 1.0 0.9 2.4 2.2 2.3 2.1 0.2 0.6 2.0 2.7 1.5 0.9 13.8 12.7 16.3 18.3 14.5 11.2 14.6 13.2 15.3 9.3 17.3 11.2 5.8 6.4 20.9 20.9 6.5 30.5 12.0 11.7 16.5 18.5 23.5 22.7 42.1 41.5 16.7 18.4 22.9 9.7 7.6 47.8 11.7 18.4 1.8 12.7 10.8 8.5 25.8 22.1 9.9 18.3 8.2 6.8 22.4 24.6 1.3 18.1 6.8 122.1 13.1 8.4 11.4 38.8 14.2 10.3 6.3 4.0 5.0 7.9 21.4 4.7 7.4 6.5 2.1 7.5 6.2 19.6 21.2 6.0 11.7 22.9 39.2 35.1 14.1 17.1 6.6 12.3 11.3 8.6 17.5 42.4 35.5 8.2 7.2 43.3 68.3 22.5 CMTM4 CKLFSF4 ENSG00000183723 "CKLF like MARVEL transmembrane domain containing 4" Q8IZR5 16 66614750-66696743 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 45.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 68.0;Granulosa cells: 67.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014704, HPA023890" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus, Vesicles, Plasma membrane" "HPA014704: AB_1847005, HPA023890: AB_1847007" "unprognostic (2.65e-3)" "unprognostic (1.16e-1)" "unprognostic (6.17e-3)" "unprognostic (3.43e-1)" "unprognostic (5.13e-1)" "unprognostic (8.30e-2)" "unprognostic (2.88e-2)" "unprognostic (2.65e-1)" "unprognostic (3.35e-3)" "unprognostic (6.06e-3)" "unprognostic (2.07e-2)" "unprognostic (3.08e-1)" "prognostic favorable (4.72e-9)" "unprognostic (1.41e-1)" "unprognostic (2.31e-1)" "unprognostic (4.94e-2)" "unprognostic (1.00e-1)" 4.5 5.0 36.4 2.7 34.1 2.5 5.7 32.8 34.5 3.9 28.3 16.1 11.9 4.4 20.1 6.0 10.6 2.9 4.1 43.1 37.1 26.3 4.1 8.4 0.6 42.1 41.7 3.4 19.2 32.7 14.4 2.1 35.4 7.7 12.6 7.8 11.1 3.8 3.3 7.7 12.9 3.4 41.8 2.0 31.4 6.9 45.5 0.5 38.6 2.1 1.1 3.2 4.1 41.6 16.0 12.9 7.8 19.1 2.6 4.2 31.7 6.6 5.9 3.5 5.6 24.2 17.7 0.7 10.8 3.9 4.8 20.0 19.7 7.8 5.2 1.3 17.2 1.7 5.3 15.2 5.6 1.4 3.0 6.7 13.4 4.2 8.1 11.9 2.0 2.3 8.0 4.1 5.1 18.5 0.1 3.2 8.7 28.6 8.6 3.5 10.6 4.9 15.2 14.2 17.9 7.1 27.4 14.6 9.3 5.6 15.3 3.4 4.3 6.5 7.0 1.8 6.6 1.4 3.3 0.7 8.1 3.2 7.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 36.4 34.1 32.8 34.5 43.1 37.1 42.1 41.7 35.4 41.8 45.5 41.6 2.6 22.4 11.1 32.7 0.8 5.2 8.8 21.9 4.6 9.5 23.5 10.8 7.1 15.7 19.3 23.9 8.4 5.0 1.6 51.7 13.7 15.9 1.9 20.7 2.7 4.3 39.0 0.8 68.0 24.0 29.6 3.5 27.5 12.3 4.5 67.6 1.8 6.1 2.4 30.3 37.7 24.1 20.3 2.8 0.9 3.0 2.5 1.9 3.6 7.5 4.4 24.2 0.0 37.7 51.3 30.8 19.5 3.0 0.6 29.0 30.7 19.9 40.0 11.1 6.6 3.1 8.8 6.4 7.7 7.5 5.5 2.9 0.9 2.5 43.4 19.4 CMTM5 "CKLFSF5, FLJ37521" ENSG00000166091 "CKLF like MARVEL transmembrane domain containing 5" Q96DZ9 14 23376773-23379772 "Predicted membrane proteins, Transporters" Chemotaxis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 182.4;choroid plexus: 49.5" "Cell type enhanced" "Detected in some" "Macrophages: 93.7;Muller glia cells: 32.0;Oligodendrocyte precursor cells: 20.6;Oligodendrocytes: 106.2" "Group enriched" "Detected in some" 37 "glioma: 8.4;melanoma: 3.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 20.8" "Lineage enriched" "Detected in many" 19 "granulocytes: 20.8" "Cell line enriched" "Detected in some" 7 "HEL: 91.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052338 Enhanced Approved "Golgi apparatus,Vesicles" NA NA 540000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "Golgi apparatus, Vesicles" "HPA052338: AB_2681793" "unprognostic (2.73e-3)" "unprognostic (1.51e-1)" "unprognostic (5.24e-1)" "unprognostic (2.43e-3)" "unprognostic (2.63e-1)" "unprognostic (6.40e-2)" "unprognostic (8.34e-3)" "unprognostic (1.78e-1)" "unprognostic (2.27e-2)" "unprognostic (8.40e-2)" "unprognostic (6.24e-4)" "unprognostic (3.03e-3)" "unprognostic (1.97e-3)" "unprognostic (1.17e-1)" "unprognostic (1.93e-1)" "unprognostic (1.11e-2)" 1.1 1.0 75.6 0.5 119.1 8.2 0.9 123.8 101.7 2.8 49.5 5.8 0.5 0.8 1.1 1.2 1.2 2.1 22.7 73.9 85.2 0.5 0.3 1.5 0.2 150.9 106.2 0.8 0.2 0.1 0.6 0.7 135.2 2.1 0.8 2.3 2.2 3.2 3.1 0.7 1.7 0.8 113.4 2.8 1.4 0.1 110.2 0.1 0.5 0.9 0.0 1.2 2.6 182.4 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 91.8 0.0 0.0 0.2 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 2.2 20.8 0.7 0.9 0.1 0.4 0.0 0.1 0.2 0.0 0.3 0.1 0.0 0.0 4.2 0.0 0.0 1.0 0.4 30.0 75.6 119.1 123.8 101.7 73.9 85.2 150.9 106.2 135.2 113.4 110.2 182.4 0.5 0.0 0.0 6.5 0.4 1.0 0.1 0.0 1.2 0.2 1.3 5.5 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 0.1 1.3 0.0 0.0 0.0 0.0 3.3 0.0 0.1 0.0 0.2 0.0 0.0 1.3 0.4 0.0 0.0 93.7 5.4 0.0 1.5 32.0 0.0 20.6 106.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.6 3.4 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.1 CMTM6 "CKLFSF6, FLJ20396" ENSG00000091317 "CKLF like MARVEL transmembrane domain containing 6" Q9NX76 3 32481312-32502852 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 815.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026980, HPA063491" Enhanced Approved Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 41: Macrophages - Immune response" Vesicles "HPA026980: AB_10602801, HPA063491: " "unprognostic (1.32e-2)" "unprognostic (3.04e-1)" "unprognostic (3.34e-2)" "unprognostic (1.81e-2)" "unprognostic (7.25e-2)" "unprognostic (8.20e-2)" "unprognostic (2.95e-2)" "unprognostic (1.99e-1)" "unprognostic (2.44e-3)" "unprognostic (2.95e-1)" "unprognostic (1.04e-3)" "unprognostic (6.79e-2)" "unprognostic (2.27e-1)" "unprognostic (7.23e-2)" "unprognostic (6.58e-2)" "unprognostic (3.74e-2)" "unprognostic (1.55e-3)" 40.3 26.2 11.6 69.0 11.4 97.3 54.4 11.7 13.5 50.4 24.8 47.7 26.7 46.3 41.0 40.3 176.6 50.3 18.5 10.8 13.4 40.0 132.4 54.3 53.9 14.5 12.5 18.6 23.5 41.6 9.2 70.1 14.3 48.6 58.4 13.0 33.2 39.9 5.0 49.4 29.5 41.6 14.5 55.4 46.9 40.4 13.5 47.8 61.7 13.6 78.3 79.0 18.9 14.7 107.4 34.2 66.5 50.1 112.1 111.0 292.4 77.5 110.4 79.7 91.5 36.6 174.4 63.5 86.1 104.6 53.8 67.6 47.0 128.9 108.2 285.4 57.3 80.4 22.8 54.5 79.6 135.3 153.0 110.5 81.3 92.0 68.6 128.2 130.3 60.9 39.8 116.0 103.0 33.4 81.9 70.0 59.3 88.6 50.0 68.6 51.7 49.9 111.1 147.9 15.3 44.3 70.5 39.5 76.1 66.9 58.3 133.5 117.8 88.0 57.9 86.7 94.1 59.6 63.9 58.6 61.4 116.8 112.1 176.8 84.4 208.0 29.1 133.4 32.8 54.4 38.1 28.3 72.7 42.2 22.0 24.7 313.4 65.1 210.2 38.6 46.3 108.6 11.6 11.4 11.7 13.5 10.8 13.4 14.5 12.5 14.3 14.5 13.5 14.7 57.0 35.3 49.9 12.4 243.7 96.0 82.4 159.3 55.2 13.9 233.0 57.5 5.8 60.1 112.0 95.6 12.5 253.6 122.5 88.0 33.2 113.8 12.3 129.1 68.3 70.7 132.1 41.2 14.2 83.0 101.7 74.9 63.2 180.9 126.8 186.5 124.9 305.2 156.5 50.5 19.2 117.6 118.0 310.1 815.8 8.4 39.4 326.0 81.8 30.0 425.8 130.1 71.1 18.1 9.4 136.7 46.1 42.9 104.7 147.1 23.8 63.4 183.0 17.3 39.5 32.9 74.3 36.1 20.2 89.7 126.6 261.7 120.9 50.3 64.6 110.3 CMTR1 "FTSJD2, ISG95, KIAA0082, MTr1" ENSG00000137200 "Cap methyltransferase 1" Q8N1G2 6 37433219-37482827 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "mRNA capping, mRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 253.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029954, HPA029979, HPA029980" Enhanced Enhanced Nucleoplasm,Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 71: Testis - DNA repair" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm Vesicles "HPA029954: AB_10670558, HPA029979: AB_10671363, HPA029980: AB_10671094" "unprognostic (1.33e-1)" "unprognostic (2.12e-2)" "unprognostic (6.43e-2)" "prognostic unfavorable (1.73e-5)" "unprognostic (1.00e-1)" "unprognostic (3.72e-1)" "unprognostic (1.68e-2)" "unprognostic (6.43e-3)" "unprognostic (2.95e-2)" "unprognostic (9.17e-2)" "unprognostic (5.24e-3)" "unprognostic (1.50e-3)" "unprognostic (3.00e-3)" "unprognostic (3.27e-2)" "unprognostic (9.72e-2)" "unprognostic (2.54e-1)" "unprognostic (1.14e-2)" 20.1 22.1 21.0 19.2 21.2 30.9 19.5 20.3 22.9 23.6 18.6 26.8 18.1 23.1 17.4 16.9 22.4 15.1 25.1 20.7 22.0 19.4 21.8 20.4 25.3 21.5 21.0 28.0 22.1 27.5 26.0 24.9 20.3 21.9 15.2 28.5 21.7 18.4 30.1 23.2 23.2 20.4 20.2 28.8 21.9 62.9 23.5 30.9 20.3 23.4 25.6 21.6 20.0 20.2 23.5 21.9 31.0 50.7 34.2 31.1 37.4 27.5 37.7 68.1 75.9 33.3 15.3 48.6 30.5 40.7 63.8 25.7 39.7 28.4 51.7 33.8 35.2 26.8 26.8 37.2 26.3 38.9 17.6 27.1 20.9 37.6 26.7 35.7 32.2 44.3 60.6 34.5 36.3 38.5 49.8 34.6 15.6 15.7 20.7 39.0 36.7 28.1 22.0 28.2 34.2 25.6 30.8 23.4 40.2 22.1 39.8 29.7 30.0 40.7 30.3 16.3 31.1 39.3 21.8 253.0 16.0 40.1 45.6 4.2 5.4 3.5 4.9 7.1 4.1 5.5 4.3 5.2 5.1 3.8 4.7 3.9 3.3 5.6 5.5 4.2 6.1 4.6 21.0 21.2 20.3 22.9 20.7 22.0 21.5 21.0 20.3 20.2 23.5 20.2 11.3 9.6 9.2 5.9 12.0 3.6 3.9 4.0 8.6 14.2 6.3 5.5 10.4 8.6 11.5 7.3 33.3 18.0 15.4 5.3 0.0 4.5 20.2 7.7 15.4 9.6 8.4 6.5 15.1 8.5 8.0 8.8 11.7 8.9 3.8 24.9 7.9 10.1 7.5 11.8 13.9 8.4 4.1 7.5 2.3 11.3 7.8 9.5 3.6 14.0 11.5 8.8 7.2 10.6 14.2 8.5 3.3 6.8 12.4 4.3 4.7 4.0 11.2 11.9 6.6 8.5 13.5 16.8 10.6 5.8 4.7 20.8 11.5 22.0 6.9 3.6 CMYA5 "C5orf10, DKFZp451G223, SPRYD2, TRIM76" ENSG00000164309 "Cardiomyopathy associated 5" Q8N3K9 5 79689836-79800240 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 623.5;tongue: 799.5" "Cell type enriched" "Detected in many" 15 "Cardiomyocytes: 3425.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 1.3;RT4: 1.5;THP-1: 5.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA074081, HPA077831" Enhanced Approved "Nuclear speckles,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles, Cytosol" "Vesicles, Plasma membrane" "HPA074081: , HPA077831: " "unprognostic (5.53e-2)" "unprognostic (9.91e-3)" "unprognostic (1.21e-2)" "unprognostic (1.49e-2)" "unprognostic (9.01e-4)" "unprognostic (7.00e-2)" "unprognostic (7.39e-2)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (1.75e-1)" "unprognostic (5.04e-1)" "unprognostic (1.93e-1)" "unprognostic (1.93e-2)" "unprognostic (6.30e-3)" "unprognostic (3.88e-2)" "unprognostic (7.69e-2)" "unprognostic (9.74e-2)" 0.9 0.1 1.4 0.2 1.4 0.0 3.9 1.2 2.1 1.7 3.1 1.3 0.1 5.9 4.6 6.6 2.1 0.9 155.8 0.6 0.6 2.5 1.2 0.5 0.0 1.6 2.0 14.6 0.3 3.6 2.0 1.1 1.1 6.1 0.2 1.7 6.1 2.1 623.5 2.2 0.4 4.6 1.1 0.0 0.6 0.5 1.7 0.9 2.3 799.5 0.1 2.1 1.2 0.8 0.0 0.0 0.0 0.1 0.5 0.4 0.6 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 1.0 5.4 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.4 1.2 2.1 0.6 0.6 1.6 2.0 1.1 1.1 1.7 0.8 2.7 9.6 2.8 69.5 0.4 1.3 17.9 2.9 4.6 2.0 24.4 46.6 3425.2 5.7 12.2 25.8 0.0 21.4 1.3 0.4 17.6 0.7 0.3 29.3 7.2 19.7 1.8 0.0 32.9 0.4 2.9 113.7 3.6 55.2 1.3 2.5 0.4 2.3 2.1 217.0 10.7 0.2 8.2 0.6 1.6 2.3 14.9 1.4 0.0 6.5 0.1 8.8 2.1 156.3 2.9 0.6 0.2 13.5 0.6 4.8 0.0 15.4 6.2 3.0 0.0 165.6 23.1 2.5 2.0 2.2 5.4 32.8 1.2 1.7 0.2 18.1 CNGA1 "CNCG, CNCG1, CNG1, RCNC1, RCNCa, RP49" ENSG00000198515 "Cyclic nucleotide gated channel subunit alpha 1" P29973 4 47935977-48016681 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "retina: 264.4" "Cell type enriched" "Detected in many" 6 "Rod photoreceptor cells: 1139.7" "Cancer enhanced" "Detected in many" "urothelial cancer: 4.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.2;RT4: 7.2;U-2 OS: 3.0" "Region enhanced" "Detected in single" "basal ganglia: 1.0" "Not detected" "Not detected" HPA076168 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 79: Retina - Phototransduction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 46: Photoreceptor cells - Phototransduction" "Vesicles, Plasma membrane" Nucleoplasm "HPA076168: AB_2686781" "unprognostic (2.68e-2)" "unprognostic (4.90e-2)" "unprognostic (1.33e-1)" "unprognostic (8.59e-2)" "unprognostic (2.07e-1)" "unprognostic (1.11e-2)" "unprognostic (1.76e-2)" "unprognostic (3.85e-2)" "unprognostic (1.12e-1)" "unprognostic (1.98e-2)" "unprognostic (3.18e-1)" "unprognostic (2.91e-1)" "unprognostic (5.48e-6)" "unprognostic (1.86e-1)" "unprognostic (1.04e-1)" "unprognostic (4.66e-2)" "unprognostic (8.23e-2)" 3.3 0.4 0.5 0.8 1.4 0.3 1.5 1.6 0.9 1.0 0.6 3.6 2.2 0.4 9.3 9.0 4.1 1.1 0.4 0.7 0.8 2.4 23.5 0.3 0.1 0.4 0.3 0.1 0.8 4.1 0.3 1.0 0.4 2.6 2.4 264.4 4.3 1.7 5.0 5.1 6.3 0.3 0.1 3.4 2.8 0.4 0.7 0.3 0.7 1.3 0.5 3.7 1.9 0.6 2.3 0.9 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.2 2.0 9.2 0.1 0.5 0.0 2.7 1.4 0.2 0.3 0.1 0.0 0.6 0.0 0.2 0.8 0.0 0.1 0.2 0.0 0.4 0.0 0.0 0.9 0.0 0.8 0.7 0.5 0.2 0.9 0.0 0.1 0.4 1.1 2.2 0.1 0.0 0.1 0.4 7.2 0.3 0.0 0.2 0.5 0.1 0.2 0.9 0.0 0.3 0.2 3.0 0.1 0.1 0.7 0.8 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.2 0.3 0.0 0.5 0.0 0.0 0.5 1.4 1.6 0.9 0.7 0.8 0.4 0.3 0.4 0.1 0.7 0.6 7.3 0.0 0.0 0.7 0.1 0.1 1.8 0.5 0.6 97.7 8.7 1.8 0.7 5.7 3.4 62.5 91.8 0.0 0.0 10.6 0.0 10.1 0.4 2.5 0.4 8.7 0.0 2.7 1.2 6.6 0.0 0.3 0.0 3.6 0.0 0.0 0.0 38.0 1.7 45.4 1.1 4.0 0.0 0.8 0.0 0.1 0.3 0.5 0.0 7.5 0.0 163.9 0.0 0.0 0.2 2.1 16.4 0.0 0.0 3.7 24.5 0.4 0.8 1139.7 0.0 0.6 17.1 0.6 1.3 10.3 2.7 0.3 0.2 0.1 4.7 35.1 CNGB1 "CNCG2, CNCG3L, CNGB1B, GAR1, GARP, RCNC2, RCNCb, RP45" ENSG00000070729 "Cyclic nucleotide gated channel subunit beta 1" Q14028 16 57882340-57971128 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Olfaction, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "retina: 600.2" "Group enriched" "Detected in some" 8 "Cone photoreceptor cells: 331.5;Rod photoreceptor cells: 1111.1" "Cancer enriched" "Detected in single" 6 "head and neck cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.5;RPMI-8226: 1.8;SCLC-21H: 5.0;SiHa: 2.9;SK-BR-3: 1.4" "Region enhanced" "Detected in some" "hypothalamus: 4.5" "HPA039159, HPA060355" Approved Vesicles,Cytosol No NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol Vesicles "HPA039159: AB_10795579, HPA060355: " "unprognostic (5.52e-3)" "unprognostic (4.51e-3)" "unprognostic (1.06e-1)" "unprognostic (2.73e-3)" "unprognostic (6.20e-2)" "unprognostic (1.76e-1)" "unprognostic (8.56e-4)" "unprognostic (3.08e-1)" "unprognostic (9.84e-2)" "unprognostic (2.83e-1)" "unprognostic (2.14e-4)" "unprognostic (5.42e-2)" "unprognostic (1.01e-3)" "unprognostic (5.20e-2)" "unprognostic (1.88e-1)" "unprognostic (4.57e-2)" "unprognostic (9.07e-2)" 0.1 2.5 15.5 1.1 13.2 0.2 0.0 0.0 20.4 0.0 0.0 0.6 0.1 0.0 0.2 0.0 0.1 0.3 0.0 24.5 24.8 0.0 0.1 0.1 0.2 2.8 3.2 0.0 0.5 0.0 0.2 0.4 4.4 0.0 0.4 600.2 0.0 0.1 0.0 0.2 0.6 0.1 2.4 0.1 0.0 0.4 36.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 1.5 0.0 0.5 0.0 0.0 1.3 0.0 0.1 0.0 0.3 0.9 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 1.8 0.0 0.6 5.0 0.0 2.9 1.4 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.2 0.0 0.1 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 15.5 13.2 0.0 20.4 24.5 24.8 2.8 3.2 4.4 2.4 36.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.4 0.0 61.6 0.3 0.0 1.1 0.0 0.1 0.0 331.5 6.9 0.0 0.0 0.0 0.4 1.6 0.9 0.1 4.2 0.0 0.0 3.2 0.4 0.9 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.4 25.2 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 89.5 0.0 1.0 0.1 0.2 1.1 0.0 0.0 0.2 0.0 0.3 0.0 1111.1 0.0 0.1 0.2 0.5 0.7 0.0 0.0 1.4 0.1 0.1 0.0 0.2 CNIH1 "CNIH, CNIL, TGAM77" ENSG00000100528 "Cornichon family AMPA receptor auxiliary protein 1" O95406 14 54423561-54441391 "Predicted membrane proteins, Transporters" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002544 Approved Uncertain Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA002544: AB_2081856" "unprognostic (1.06e-1)" "unprognostic (1.18e-3)" "unprognostic (7.09e-2)" "unprognostic (5.06e-2)" "unprognostic (1.50e-1)" "unprognostic (8.93e-3)" "unprognostic (1.47e-1)" "unprognostic (2.71e-3)" "unprognostic (4.78e-2)" "unprognostic (4.62e-1)" "unprognostic (1.38e-2)" "unprognostic (1.79e-1)" "unprognostic (4.12e-2)" "unprognostic (1.28e-1)" "unprognostic (1.47e-1)" "unprognostic (1.71e-2)" "prognostic unfavorable (8.95e-4)" 73.2 61.7 40.2 50.9 42.1 37.2 73.6 45.2 49.5 59.8 58.5 86.9 99.4 49.6 50.8 72.5 67.0 74.4 84.6 42.8 47.2 79.9 232.9 46.7 61.2 44.3 43.4 44.0 41.8 59.8 41.2 58.4 44.8 57.2 95.1 60.3 49.7 57.1 58.9 36.0 85.4 68.2 49.1 33.8 45.4 37.1 41.3 56.2 65.0 95.5 79.0 95.1 39.4 50.7 233.4 141.3 113.8 129.2 301.0 380.9 107.8 276.8 348.6 232.0 264.4 86.5 316.4 289.7 180.2 209.2 141.6 226.5 208.3 200.3 287.5 111.9 124.5 112.1 80.9 152.8 303.6 136.5 90.2 314.4 244.3 217.1 304.0 236.8 221.3 117.7 111.5 95.5 262.4 138.4 151.5 102.9 84.2 266.3 281.3 114.8 191.8 97.3 264.2 171.4 95.5 106.3 163.4 127.8 316.7 104.8 197.5 144.9 143.7 194.7 192.9 165.4 167.8 59.7 138.8 141.2 235.9 115.3 176.5 5.3 84.6 10.7 32.5 66.8 54.8 64.3 57.3 47.0 86.0 55.2 75.1 52.1 20.9 44.0 53.7 48.4 65.1 96.6 40.2 42.1 45.2 49.5 42.8 47.2 44.3 43.4 44.8 49.1 41.3 50.7 41.1 35.3 60.6 14.7 64.9 105.7 86.2 186.1 141.7 41.9 69.2 64.0 85.6 50.1 79.8 46.0 20.9 95.7 48.1 98.8 90.1 89.3 44.4 54.8 57.9 72.3 104.4 65.0 26.9 62.3 123.4 90.3 52.5 32.8 197.3 32.4 70.3 140.0 115.5 67.3 34.8 91.5 99.7 102.8 80.0 17.0 60.0 73.5 83.6 9.4 110.3 59.9 35.0 17.6 22.5 65.6 96.6 65.8 84.0 92.0 149.9 164.7 79.9 45.1 46.0 60.5 68.1 68.7 64.1 144.9 110.0 70.9 69.3 68.4 123.0 91.4 CNNM2 ACDP2 ENSG00000148842 "Cyclin and CBS domain divalent metal cation transport mediator 2" Q9H8M5 10 102918294-103090222 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Disease variant, Epilepsy, Mental retardation, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 37.9;parathyroid gland: 31.6" "Cell type enhanced" "Detected in many" "Astrocytes: 60.1;Excitatory neurons: 112.6;Inhibitory neurons: 146.9;Oligodendrocyte precursor cells: 92.5;Oligodendrocytes: 92.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 1.5" "Lineage enriched" "Detected in single" 4 "NK-cells: 1.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059954, HPA071631" Enhanced Vesicles NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 16: U-266 - Nucleosome" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA059954: AB_2684177, HPA071631: AB_2686427" "unprognostic (2.18e-1)" "unprognostic (6.46e-2)" "unprognostic (1.24e-1)" "unprognostic (2.65e-3)" "unprognostic (3.19e-1)" "unprognostic (2.44e-1)" "unprognostic (1.93e-1)" "unprognostic (4.80e-2)" "unprognostic (4.51e-3)" "unprognostic (3.75e-2)" "unprognostic (1.29e-2)" "unprognostic (2.39e-1)" "prognostic favorable (2.39e-8)" "unprognostic (2.44e-1)" "unprognostic (1.13e-1)" "unprognostic (2.65e-3)" "unprognostic (1.56e-1)" 3.3 11.5 5.1 2.3 5.5 9.3 2.5 7.9 5.7 3.7 37.9 7.0 3.8 3.6 2.1 1.7 4.8 4.1 2.1 4.2 3.3 9.1 4.8 3.8 1.5 4.9 4.8 4.8 3.6 31.6 5.7 8.7 4.7 2.7 6.4 5.0 3.0 3.0 1.6 4.5 4.5 3.7 1.8 2.1 3.3 4.5 4.6 1.8 5.6 1.5 1.1 3.2 2.9 9.7 5.0 8.1 3.1 8.5 7.8 3.2 8.6 2.3 9.7 3.1 3.9 5.8 4.3 1.9 3.5 3.4 6.0 6.3 6.9 4.6 2.4 3.3 12.1 2.8 4.2 11.8 4.6 2.0 3.6 4.2 6.6 3.2 10.7 7.9 1.9 5.5 4.8 10.9 1.8 8.6 2.3 2.2 5.1 4.9 5.0 5.5 4.0 2.4 2.4 2.9 4.5 5.8 5.9 1.3 6.3 9.1 10.4 3.7 1.6 4.2 6.2 3.0 4.2 11.7 14.1 3.6 7.4 6.6 1.7 0.3 0.1 0.1 0.2 0.2 0.2 0.3 0.1 0.1 0.1 0.1 0.2 0.1 0.2 1.5 0.0 0.3 0.3 0.1 5.1 5.5 7.9 5.7 4.2 3.3 4.9 4.8 4.7 1.8 4.6 9.7 3.0 6.4 8.4 60.1 7.9 2.4 2.3 1.7 6.8 16.4 3.3 2.4 4.5 2.8 5.6 5.5 12.5 18.8 8.1 46.7 1.9 2.2 10.7 7.4 4.2 4.2 6.7 6.7 112.6 5.4 3.4 6.3 12.8 6.4 3.8 13.7 3.3 6.1 3.8 32.0 146.9 5.0 0.0 3.2 2.5 15.1 3.4 4.7 7.2 39.4 2.3 7.0 2.1 92.5 92.3 2.3 9.0 3.4 6.2 2.0 11.7 5.5 9.5 15.8 13.1 5.7 16.7 15.5 6.9 8.1 4.1 39.8 5.1 3.8 11.6 2.2 CNPY4 "MGC40499, PRAT4B" ENSG00000166997 "Canopy FGF signaling regulator 4" Q8N129 7 100119634-100125508 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 35.3;Leydig cells: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014166, HPA025240" Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA014166: AB_1853895, HPA025240: AB_2082630" "unprognostic (9.64e-2)" "unprognostic (1.59e-2)" "unprognostic (4.09e-3)" "unprognostic (8.44e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.71e-1)" "prognostic unfavorable (3.99e-4)" "unprognostic (2.86e-1)" "unprognostic (1.35e-1)" "unprognostic (1.47e-1)" "unprognostic (6.16e-3)" "unprognostic (1.07e-1)" "prognostic unfavorable (3.59e-5)" "unprognostic (6.92e-2)" "unprognostic (1.80e-1)" "unprognostic (1.88e-1)" "unprognostic (1.35e-2)" 13.7 16.8 13.3 9.6 13.9 6.1 11.0 14.3 14.9 24.6 14.7 14.1 6.4 21.2 14.8 5.7 15.4 16.7 13.1 13.1 13.7 10.4 6.6 9.2 10.8 14.2 13.8 24.5 4.5 12.8 16.6 21.3 14.1 10.8 9.9 17.2 5.7 15.9 5.1 8.3 9.7 21.4 13.8 13.6 7.8 6.8 13.6 14.3 10.4 7.1 9.8 12.4 14.8 14.3 7.9 13.5 33.2 59.6 76.0 36.5 16.6 29.0 31.2 14.9 27.8 7.5 7.0 17.2 32.9 52.5 10.9 7.9 13.0 14.2 15.6 16.2 13.4 7.1 23.3 10.4 21.5 12.1 12.8 33.4 3.8 13.7 6.2 32.7 52.4 8.2 6.0 11.1 21.5 22.9 25.8 15.9 17.1 5.0 19.2 7.5 24.9 9.2 15.4 2.0 8.3 16.9 27.8 22.4 15.4 21.4 11.3 6.7 42.9 47.5 28.5 20.2 13.3 9.4 16.3 15.3 27.8 18.4 19.7 11.8 5.1 8.6 15.1 11.2 19.8 3.9 15.6 19.0 7.2 2.9 12.7 19.0 2.3 12.3 13.9 4.6 13.8 6.7 13.3 13.9 14.3 14.9 13.1 13.7 14.2 13.8 14.1 13.8 13.6 14.3 15.2 6.4 2.6 4.2 3.4 3.6 2.3 7.9 2.8 6.9 3.4 6.2 3.4 5.7 4.0 12.9 2.1 35.3 5.2 3.7 1.9 6.4 0.5 5.1 20.2 15.0 2.4 11.8 3.4 2.5 10.3 28.4 1.1 4.2 9.5 16.1 18.2 1.3 14.0 8.4 4.0 1.9 4.1 2.5 2.4 2.2 35.1 4.7 16.0 2.8 5.1 26.6 8.2 2.0 2.8 2.4 2.8 31.6 1.9 0.5 2.8 3.3 4.4 15.8 13.1 12.7 15.5 1.1 4.5 2.1 3.8 18.3 8.6 30.5 2.3 1.0 CNST "C1orf71, FLJ32001, PPP1R64" ENSG00000162852 "Consortin, connexin sorting protein" Q6PJW8 1 246566444-246668595 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007225, HPA007226" Approved Supported Vesicles NA NA 480000 "Cluster 37: B-cells - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Vesicles "HPA007225: AB_1848869, HPA007226: AB_2667782" "unprognostic (1.55e-2)" "unprognostic (9.75e-2)" "unprognostic (3.33e-2)" "unprognostic (9.76e-2)" "unprognostic (2.78e-1)" "unprognostic (4.28e-2)" "unprognostic (3.72e-2)" "unprognostic (7.28e-3)" "unprognostic (1.01e-1)" "unprognostic (1.93e-1)" "unprognostic (3.52e-2)" "unprognostic (3.47e-2)" "unprognostic (2.73e-3)" "unprognostic (6.17e-2)" "unprognostic (2.63e-1)" "unprognostic (8.77e-3)" "unprognostic (2.26e-1)" 13.1 19.2 8.8 10.5 9.7 23.5 10.9 14.4 16.1 9.0 17.1 13.7 10.2 9.0 8.1 16.7 8.8 8.7 8.9 10.3 11.1 8.6 23.5 9.9 16.7 6.9 7.8 10.5 10.2 11.3 7.5 9.3 8.4 8.1 12.0 16.8 7.2 7.3 31.8 10.1 13.2 10.1 5.6 10.4 8.4 12.9 7.6 14.3 13.9 39.0 13.4 11.3 8.8 9.5 8.4 11.0 7.9 7.0 12.8 14.7 16.0 26.9 26.5 26.7 20.2 10.5 10.9 24.6 11.7 26.9 7.9 8.6 12.3 9.2 36.2 13.8 4.2 28.9 10.4 8.0 18.4 14.5 53.5 14.0 8.7 25.9 27.4 13.2 8.4 13.0 37.3 10.5 15.3 6.1 15.9 6.7 25.9 11.7 9.5 15.5 14.2 20.1 10.1 24.4 18.0 21.6 11.5 6.7 34.0 9.2 12.3 12.6 12.0 33.0 7.9 13.8 18.5 31.8 43.8 25.0 8.1 21.2 32.5 47.1 8.1 23.9 14.4 8.8 16.1 35.6 24.8 13.6 8.1 35.7 31.1 16.9 10.7 15.1 22.2 11.7 33.2 15.9 8.8 9.7 14.4 16.1 10.3 11.1 6.9 7.8 8.4 5.6 7.6 9.5 41.3 12.8 17.2 21.2 46.0 24.9 21.5 6.7 27.3 31.5 10.2 7.5 14.3 12.8 17.7 3.7 14.6 4.0 18.2 46.9 7.9 6.9 44.7 43.7 17.2 29.0 15.0 25.2 58.5 6.0 6.2 22.5 16.3 68.3 40.4 8.1 30.0 22.1 10.0 16.8 54.1 19.3 10.2 12.5 12.2 41.6 9.6 32.9 14.2 22.5 10.1 14.9 18.6 43.2 35.7 8.8 31.4 7.9 26.4 16.4 42.7 5.9 23.4 24.4 13.1 20.6 29.2 16.7 13.1 20.6 26.9 9.3 31.7 8.3 14.3 23.3 CNTD1 "CNTD, FLJ40137" ENSG00000176563 "Cyclin N-terminal domain containing 1" Q8N815 17 42798800-42811587 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "testis: 42.4" "Group enriched" "Detected in many" 5 "Early spermatids: 70.5;Late spermatids: 124.8;Respiratory ciliated cells: 47.0;Spermatocytes: 150.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 2.9;ASC diff: 1.6;SiHa: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA072363 Approved Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 78: Testis - Spermatogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm Vesicles "HPA072363: " "unprognostic (5.92e-2)" "unprognostic (1.99e-3)" "unprognostic (3.66e-2)" "unprognostic (2.13e-2)" "unprognostic (1.25e-1)" "unprognostic (6.29e-3)" "unprognostic (6.61e-2)" "unprognostic (1.09e-2)" "unprognostic (7.82e-2)" "unprognostic (6.18e-2)" "unprognostic (1.36e-2)" "unprognostic (2.07e-1)" "unprognostic (5.89e-7)" "unprognostic (1.52e-1)" "unprognostic (1.90e-1)" "unprognostic (2.35e-1)" "unprognostic (1.81e-4)" 0.3 0.2 0.9 0.0 0.9 0.1 1.8 1.2 1.9 0.1 0.1 0.8 0.1 0.1 1.4 0.0 0.7 0.0 0.1 0.9 1.0 1.5 0.0 0.5 0.0 1.0 0.9 0.4 1.0 0.3 0.0 0.1 0.9 1.3 1.9 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.8 0.1 3.3 42.4 0.8 0.0 0.3 0.6 0.0 0.2 0.0 1.9 2.9 0.3 0.2 0.5 1.6 0.4 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.2 0.2 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.1 0.2 0.0 0.0 0.0 1.5 0.1 0.3 0.0 0.8 0.0 0.0 0.7 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.9 0.9 1.2 1.9 0.9 1.0 1.0 0.9 0.9 0.8 0.8 1.9 1.2 3.2 4.6 2.3 1.0 0.4 0.5 0.4 0.0 1.7 5.5 2.2 1.1 1.5 2.1 0.0 0.0 0.3 1.2 1.4 5.9 0.2 70.5 5.4 1.7 0.8 0.0 2.7 1.9 0.4 0.4 1.9 4.1 1.6 6.3 0.2 0.4 1.1 0.3 6.7 1.6 5.3 4.1 1.0 0.7 124.8 2.5 1.1 0.0 0.0 0.2 1.0 0.0 2.0 1.1 0.4 0.4 1.2 0.7 5.6 0.9 0.5 47.0 0.7 6.6 1.0 1.7 150.2 17.1 0.0 0.6 0.3 0.9 0.5 2.7 2.3 CNTF HCNTF ENSG00000242689 "Ciliary neurotrophic factor" P26441 11 58622665-58625733 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.9;brain: 7.7" "Cell type enhanced" "Detected in single" "Melanocytes: 1.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-2197: 7.9" "Low region specificity" "Detected in all" HPA019654 Approved Approved Vesicles NA NA 69200 "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 18: U-2197 - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA019654: AB_1859050" "unprognostic (1.88e-1)" "unprognostic (2.64e-3)" "unprognostic (1.01e-2)" "unprognostic (4.37e-2)" "unprognostic (1.52e-1)" "unprognostic (5.91e-2)" "unprognostic (1.63e-1)" "unprognostic (9.24e-2)" "unprognostic (5.87e-2)" "unprognostic (1.63e-1)" "unprognostic (8.25e-4)" "unprognostic (5.42e-2)" "unprognostic (8.50e-2)" "unprognostic (1.02e-1)" "unprognostic (1.91e-1)" "unprognostic (9.50e-2)" "unprognostic (9.67e-2)" 0.9 0.5 1.2 0.6 3.0 6.9 0.7 2.9 2.4 0.2 1.2 0.6 0.9 0.2 0.9 0.6 4.7 0.5 1.6 1.1 2.0 0.6 0.8 0.6 0.5 5.8 3.6 0.2 0.5 0.4 0.4 0.4 3.9 0.3 0.8 0.8 1.1 0.3 3.2 0.9 0.7 0.4 3.4 0.4 0.4 0.6 2.2 0.7 0.6 1.8 0.4 0.4 0.3 7.7 1.3 0.5 2.1 2.2 0.6 0.2 1.1 0.9 1.4 1.0 0.7 1.9 1.8 2.8 0.7 1.4 1.1 2.4 2.3 2.5 2.0 1.9 1.3 1.4 3.1 1.0 0.3 2.2 2.5 0.6 0.8 3.2 1.0 0.4 1.0 1.9 2.2 0.6 1.3 0.5 2.1 2.1 1.3 1.0 1.0 1.3 1.4 2.0 1.2 1.6 0.9 2.6 1.4 1.5 3.7 1.5 1.8 1.6 0.7 1.5 1.1 7.9 2.6 1.4 3.3 2.3 4.0 1.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 3.0 2.9 2.4 1.1 2.0 5.8 3.6 3.9 3.4 2.2 7.7 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.5 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.2 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.1 CNTNAP5 "caspr5, FLJ31966" ENSG00000155052 "Contactin associated protein family member 5" Q8WYK1 2 124025287-124915287 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 7.9" "Group enriched" "Detected in some" 49 "Excitatory neurons: 554.6;Inhibitory neurons: 906.4;Oligodendrocyte precursor cells: 760.0" "Cancer enhanced" "Detected in single" "renal cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.2;SH-SY5Y: 2.6" "Low region specificity" "Detected in all" "HPA069095, HPA069356" Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoli fibrillar center" "Nucleoplasm, Vesicles" "HPA069095: AB_2686083, HPA069356: AB_2686127" "unprognostic (6.32e-3)" "unprognostic (6.38e-2)" "unprognostic (1.23e-1)" "unprognostic (2.25e-1)" "unprognostic (1.68e-1)" "unprognostic (7.53e-2)" "unprognostic (6.20e-2)" "unprognostic (3.11e-2)" "unprognostic (2.62e-6)" "unprognostic (3.65e-3)" "unprognostic (5.32e-2)" "unprognostic (9.58e-2)" 0.0 0.5 2.4 0.0 0.6 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 4.3 5.1 0.1 0.0 0.0 0.0 6.8 6.3 0.0 0.1 0.0 0.0 0.0 7.3 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.6 0.0 7.9 4.3 5.1 6.8 6.3 7.3 0.0 7.2 0.8 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.0 0.0 0.1 0.0 0.0 554.6 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 906.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 9.4 0.0 1.0 0.0 760.0 11.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 COCH "COCH-5B2, DFNA31, DFNA9" ENSG00000100473 Cochlin O43405 14 30874514-30895065 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Hearing "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "pancreas: 502.0" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 63.0;Horizontal cells: 84.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 71.3" "Group enriched" "Detected in some" 12 "memory B-cell: 38.3;naive B-cell: 17.7" "Lineage enriched" "Detected in many" 17 "B-cells: 38.3" "Cell line enhanced" "Detected in many" "HEK 293: 95.7;Hep G2: 63.8;K-562: 129.1;NB-4: 105.5;SCLC-21H: 111.8" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 50.8" HPA065086 Supported Vesicles "Secreted in other tissues" NA NA 160000 "Cluster 19: B-cells - Humoral immune response" "Cluster 25: Pancreas - Digestion" "Cluster 1: K-562 - Erythropoiesis" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA065086: " "unprognostic (8.36e-3)" "unprognostic (2.51e-2)" "unprognostic (8.61e-2)" "unprognostic (1.64e-2)" "unprognostic (6.48e-2)" "unprognostic (6.53e-2)" "unprognostic (9.61e-2)" "unprognostic (4.03e-1)" "unprognostic (2.11e-2)" "unprognostic (1.40e-1)" "unprognostic (1.27e-2)" "unprognostic (2.91e-3)" "unprognostic (5.42e-3)" "unprognostic (3.92e-2)" "unprognostic (2.80e-2)" "unprognostic (1.03e-1)" "unprognostic (1.72e-1)" 3.2 3.7 7.3 2.8 71.3 4.0 3.4 1.4 20.9 17.4 19.0 3.2 0.8 0.6 2.2 0.9 6.2 2.9 1.9 5.6 8.0 5.2 0.5 0.6 11.0 2.9 7.9 0.8 502.0 3.4 10.1 1.9 3.7 48.3 2.2 12.1 3.6 73.4 1.3 15.2 2.6 1.1 6.2 2.6 1.7 5.2 12.5 1.3 1.3 5.0 7.7 2.0 23.0 1.7 0.0 35.3 3.1 0.0 0.6 0.1 21.8 0.2 0.0 6.4 17.1 20.9 1.2 0.4 1.7 0.0 1.3 0.1 22.2 0.0 10.6 0.0 95.7 18.1 7.6 63.8 0.0 1.8 7.3 1.3 0.0 0.6 0.0 0.0 0.3 39.9 129.1 5.1 1.6 0.8 9.2 105.5 11.9 0.1 3.7 26.7 0.0 0.9 1.1 3.4 111.8 30.4 2.6 0.6 0.2 12.1 0.0 48.7 0.9 0.0 0.0 0.3 0.1 5.7 15.8 11.2 0.0 0.0 4.7 0.0 0.6 0.0 0.0 0.0 0.0 38.3 0.3 0.0 0.1 17.7 0.0 0.1 0.2 0.0 0.0 0.0 2.2 1.0 7.3 71.3 1.4 20.9 5.6 8.0 2.9 7.9 3.7 6.2 12.5 1.7 2.0 0.0 0.5 3.6 13.4 19.1 2.3 0.3 0.0 2.7 7.9 1.5 0.8 2.8 0.9 0.0 4.2 6.5 1.3 0.6 1.9 0.5 1.5 2.2 0.8 3.1 17.0 7.4 14.3 63.0 14.3 22.0 1.1 1.0 1.3 1.8 5.0 5.0 3.8 84.1 24.2 0.3 6.1 5.0 25.2 2.0 1.5 2.4 19.6 7.5 2.8 14.5 0.0 6.0 16.5 3.7 4.3 6.0 10.0 3.5 0.2 11.7 0.5 4.0 0.0 2.8 9.0 22.1 20.3 0.1 13.5 6.6 3.3 0.1 0.6 1.7 COG4 "COD1, DKFZP586E1519" ENSG00000103051 "Component of oligomeric golgi complex 4" 16 70480568-70523560 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040924, HPA042539" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus" Vesicles "HPA040924: AB_2677203, HPA042539: AB_2678044" "unprognostic (1.30e-1)" "unprognostic (2.11e-2)" "unprognostic (1.38e-1)" "unprognostic (6.24e-2)" "unprognostic (6.08e-2)" "unprognostic (1.41e-2)" "prognostic unfavorable (1.64e-5)" "unprognostic (3.36e-2)" "unprognostic (1.21e-1)" "unprognostic (2.35e-1)" "unprognostic (2.30e-1)" "unprognostic (1.37e-1)" "unprognostic (1.25e-2)" "unprognostic (3.02e-1)" "unprognostic (3.35e-1)" "unprognostic (1.99e-2)" "unprognostic (1.79e-1)" 17.8 22.0 25.3 12.8 27.2 14.2 15.7 27.8 27.0 20.2 29.0 20.3 10.5 17.4 11.1 30.1 19.7 12.8 25.7 25.3 26.5 16.9 16.9 18.3 15.4 26.9 26.3 18.8 10.6 27.9 19.0 19.8 26.6 14.4 16.6 14.5 17.1 16.5 67.7 23.8 16.3 19.2 25.9 17.9 17.4 19.2 27.7 22.3 15.9 49.4 17.7 18.5 20.7 28.3 37.3 59.9 47.1 31.3 62.6 43.7 53.0 41.0 53.7 51.0 43.9 48.3 66.7 25.0 57.7 64.9 35.5 53.4 60.8 65.3 70.9 21.5 36.7 23.1 59.8 47.5 36.7 15.3 15.0 51.9 41.9 66.1 40.6 59.7 51.7 31.6 55.9 18.1 57.6 75.9 25.1 23.4 45.2 50.4 30.9 46.8 31.2 57.4 42.3 31.0 43.9 45.5 80.7 30.5 24.3 48.0 77.9 26.4 49.7 46.3 29.1 35.3 29.8 19.1 26.2 78.0 50.7 15.8 46.1 20.6 26.4 23.8 19.7 28.8 14.4 11.8 19.3 17.9 32.8 14.6 16.9 15.7 13.8 14.4 34.4 15.2 24.4 25.1 25.3 27.2 27.8 27.0 25.3 26.5 26.9 26.3 26.6 25.9 27.7 28.3 13.6 16.0 16.0 21.9 11.0 9.1 12.1 22.6 11.4 24.5 9.2 8.0 23.3 2.8 21.1 3.7 14.6 47.7 13.1 20.8 9.8 23.4 3.1 11.9 13.0 16.8 12.6 12.6 10.9 16.0 26.8 16.5 18.8 13.4 8.8 28.7 16.8 17.8 24.7 8.4 13.0 18.0 24.4 14.1 8.9 6.7 14.6 11.1 8.8 7.5 14.7 29.3 12.3 19.6 19.1 17.6 21.0 19.2 12.3 6.3 21.7 13.8 18.5 29.9 32.9 14.0 18.6 37.5 25.7 13.1 10.7 39.0 12.9 37.3 19.4 8.9 COL12A1 COL12A1L ENSG00000111799 "Collagen type XII alpha 1 chain" Q99715 6 75084326-75206267 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Endometrial stromal cells: 44.3;Excitatory neurons: 52.9;Fibroblasts: 99.7;Leydig cells: 60.3;Sertoli cells: 46.0;Smooth muscle cells: 48.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "fHDF/TERT166: 1432.1;SiHa: 846.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 29.1" "HPA009143, HPA010021" Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA 9100000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Cytosol "HPA009143: AB_1847095, HPA010021: " "unprognostic (2.60e-2)" "unprognostic (2.80e-3)" "unprognostic (7.92e-2)" "unprognostic (8.27e-3)" "unprognostic (1.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (3.47e-3)" "unprognostic (1.38e-1)" "unprognostic (4.30e-1)" "unprognostic (1.18e-3)" "unprognostic (3.04e-1)" "prognostic unfavorable (1.69e-9)" "unprognostic (1.03e-3)" "unprognostic (1.81e-1)" "unprognostic (3.16e-3)" "unprognostic (1.92e-2)" 105.1 15.7 2.2 16.0 1.9 0.0 65.4 0.8 2.7 112.8 0.4 74.9 8.7 124.5 5.5 36.2 42.2 20.9 25.5 1.0 1.2 25.9 3.5 24.6 7.2 1.8 4.8 123.2 5.9 5.0 4.8 1.8 0.6 20.8 17.2 0.4 16.1 42.4 14.4 48.9 40.6 72.1 0.6 11.4 18.1 4.6 2.0 5.5 19.3 12.5 4.2 26.3 45.8 0.8 0.2 2.2 11.5 0.2 270.2 162.0 28.3 275.4 229.3 186.2 257.3 27.5 0.7 0.0 27.7 1432.1 3.9 59.2 0.5 28.7 174.6 0.2 1.4 0.2 101.1 0.1 97.9 0.3 0.2 234.9 5.0 42.2 50.6 173.6 32.0 0.1 0.0 0.0 29.4 0.2 0.1 0.2 6.4 0.0 15.3 0.1 23.1 0.2 8.9 14.4 0.0 0.0 846.1 21.2 0.3 15.5 131.8 0.5 0.2 78.5 97.0 41.5 91.4 0.1 0.1 0.4 26.4 0.3 40.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.9 0.8 2.7 1.0 1.2 1.8 4.8 0.6 0.6 2.0 0.8 14.2 76.9 5.1 2.3 0.0 20.6 0.6 12.7 5.2 0.4 4.7 7.1 4.1 0.0 4.7 3.7 0.0 0.6 0.0 0.0 0.0 1.4 24.1 6.3 44.3 11.0 0.0 0.0 52.9 4.6 1.3 99.7 2.6 14.1 1.3 0.1 3.3 0.0 0.8 0.0 32.4 0.0 0.0 0.3 18.4 14.7 60.3 1.8 21.4 38.4 0.0 0.0 0.0 19.6 1.2 6.7 0.0 13.2 0.1 1.7 0.0 0.9 1.7 0.0 46.0 20.0 48.6 0.3 0.6 0.6 13.1 0.7 2.5 1.4 0.1 0.3 COL14A1 UND ENSG00000187955 "Collagen type XIV alpha 1 chain" Q05707 8 120059780-120373573 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 205.8" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1;Endometrial stromal cells: 97.0;Fibroblasts: 235.9;Smooth muscle cells: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 54.4;hTERT-RPE1: 29.7;RH-30: 123.4" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA023781 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA 3200000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA023781: AB_1847098" "unprognostic (1.10e-1)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.22e-3)" "unprognostic (5.96e-2)" "unprognostic (4.29e-2)" "unprognostic (7.61e-2)" "unprognostic (3.77e-2)" "unprognostic (4.36e-1)" "unprognostic (5.07e-2)" "prognostic unfavorable (5.79e-5)" "unprognostic (1.07e-2)" "unprognostic (8.21e-3)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.01e-4)" 69.0 16.2 1.6 42.2 1.9 0.3 58.8 1.5 2.4 205.8 2.9 39.8 7.7 78.2 35.2 50.2 46.2 142.2 45.4 1.5 2.0 32.1 19.5 27.7 12.8 3.4 2.2 83.2 15.7 6.0 4.0 152.7 2.7 43.8 53.9 0.6 13.5 24.9 7.0 13.3 35.3 147.6 3.1 28.4 25.6 5.5 2.4 5.3 43.2 36.1 16.5 108.5 93.0 3.0 0.0 0.0 0.9 0.0 5.4 54.4 0.1 0.1 6.7 0.2 0.1 0.0 0.0 0.6 1.8 8.2 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 1.8 0.0 13.2 0.2 0.2 14.4 0.3 2.6 0.0 29.7 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.4 4.2 0.0 0.0 0.0 123.4 0.2 4.8 0.0 0.5 0.2 0.1 0.1 0.1 3.2 0.0 0.1 0.0 1.3 0.3 0.2 2.9 0.4 0.0 0.2 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 1.5 2.4 1.5 2.0 3.4 2.2 2.7 3.1 2.4 3.0 8.0 0.0 1.1 0.0 0.1 11.3 0.4 2.1 75.1 0.1 1.8 25.3 13.2 0.0 4.3 1.8 0.0 34.4 0.3 0.0 0.0 0.0 1.0 6.9 97.0 7.8 0.0 0.0 5.6 0.0 4.0 235.9 6.1 11.3 3.8 0.2 18.5 0.0 6.2 0.0 5.2 0.0 0.0 0.0 18.5 1.4 14.6 1.7 5.4 5.6 0.0 0.1 0.0 1.0 3.3 0.0 0.0 15.4 0.5 0.6 0.0 0.0 0.1 0.5 0.0 4.2 118.2 4.4 2.8 3.9 9.7 25.3 2.7 4.5 0.0 0.3 COL1A1 OI4 ENSG00000108821 "Collagen type I alpha 1 chain" P02452 17 50184101-50201632 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, FDA approved drug targets, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1331.8;gallbladder: 1211.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 2044.3;Fibroblasts: 1944.4;Leydig cells: 556.0;Smooth muscle cells: 1024.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 1689.5;BJ: 3428.1;fHDF/TERT166: 5206.1;HSkMC: 2490.3;U-138 MG: 2687.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 115.9" "HPA011795, HPA012111" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 80000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA011795: AB_1847088, HPA012111: " "unprognostic (1.61e-1)" "unprognostic (3.60e-3)" "unprognostic (8.29e-2)" "unprognostic (5.52e-2)" "unprognostic (7.74e-2)" "unprognostic (2.22e-1)" "unprognostic (6.01e-2)" "prognostic unfavorable (4.43e-4)" "unprognostic (1.23e-2)" "unprognostic (2.55e-2)" "unprognostic (8.53e-2)" "unprognostic (9.90e-2)" "prognostic unfavorable (7.19e-12)" "unprognostic (2.74e-2)" "unprognostic (4.73e-2)" "unprognostic (7.26e-2)" "unprognostic (3.87e-3)" 312.1 39.9 1.8 272.8 5.3 4.5 184.9 1.3 15.9 1331.8 12.0 223.2 37.7 531.4 23.4 110.2 234.1 1211.3 126.6 1.5 1.9 34.7 29.7 139.0 78.1 3.2 1.4 377.3 39.8 14.1 80.5 503.5 2.0 137.5 46.5 0.4 51.3 98.6 21.2 362.0 86.6 801.2 2.2 46.9 109.9 38.2 17.3 14.4 50.8 13.0 21.1 616.3 342.2 6.7 6.0 5.0 16.4 3.2 702.9 1689.5 29.2 3428.1 915.8 826.6 517.6 64.2 14.6 0.6 7.8 5206.1 5.7 9.1 8.3 3.4 150.1 5.2 6.1 0.4 92.2 4.2 1309.3 1.2 0.8 2490.3 45.7 1016.2 4.6 126.9 0.5 4.8 2.2 0.4 425.4 8.5 1.4 1.0 17.0 10.7 10.5 6.1 2.1 2.7 3.9 0.2 2.0 8.8 5.6 5.0 0.2 245.4 39.8 0.6 1.5 2687.4 562.6 405.0 16.2 2.8 5.9 0.7 200.1 1.3 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 5.3 1.3 15.9 1.5 1.9 3.2 1.4 2.0 2.2 17.3 6.7 66.9 9.6 13.8 0.0 2.1 188.0 12.4 31.6 10.8 0.2 9.1 10.0 12.5 5.7 13.2 7.3 0.0 45.7 1.7 1.4 0.0 13.3 1.9 64.6 2044.3 33.4 3.0 0.0 0.1 4.2 45.5 1944.4 17.9 49.2 2.5 8.1 378.0 3.4 67.6 0.0 0.3 5.4 6.1 0.3 318.1 18.2 556.0 13.1 188.5 12.2 0.0 2.5 0.0 0.0 0.0 23.8 0.3 268.1 1.3 10.7 0.1 0.7 9.8 0.2 78.9 74.8 1024.9 4.0 2.6 4.3 163.5 111.8 29.4 57.3 2.9 9.1 COL22A1 ENSG00000169436 "Collagen type XXII alpha 1 chain" Q8NFW1 8 138588235-138914041 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "pituitary gland: 44.0" "Cell type enhanced" "Detected in some" "Early spermatids: 39.6;Excitatory neurons: 13.0;Late spermatids: 33.7;Muller glia cells: 25.5" "Cancer enhanced" "Detected in many" "testis cancer: 9.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 29.5;RT4: 12.2;SCLC-21H: 8.1;U-2 OS: 6.8" "Low region specificity" "Detected in many" HPA024830 Enhanced Supported "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Endoplasmic reticulum" "HPA024830: AB_1847102" "unprognostic (1.06e-1)" "unprognostic (1.31e-1)" "unprognostic (2.88e-2)" "unprognostic (4.19e-6)" "prognostic unfavorable (4.15e-4)" "unprognostic (1.05e-2)" "unprognostic (5.57e-3)" "prognostic unfavorable (2.13e-6)" "unprognostic (2.01e-1)" "unprognostic (9.24e-2)" "unprognostic (5.74e-2)" "unprognostic (3.62e-2)" "unprognostic (3.66e-15)" "unprognostic (2.38e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-2)" "unprognostic (1.09e-1)" 0.1 7.6 0.6 0.6 1.0 0.0 0.0 2.9 0.5 0.8 0.4 1.0 0.3 1.9 0.2 0.1 0.4 0.3 0.2 0.3 1.4 1.9 0.0 0.0 0.5 2.9 1.2 0.2 0.1 1.4 44.0 0.0 0.6 3.0 0.1 5.2 0.9 2.4 0.7 0.0 0.4 1.6 4.3 0.2 2.2 1.1 2.0 2.1 0.2 1.1 1.2 0.9 0.4 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 12.2 8.1 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 2.9 0.5 0.3 1.4 2.9 1.2 0.6 4.3 2.0 2.3 0.0 0.0 0.0 0.3 0.0 0.0 3.7 2.5 0.0 0.3 0.2 0.3 1.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 39.6 0.1 0.2 0.8 0.0 0.0 13.0 0.2 0.0 0.2 0.0 0.6 0.0 0.6 0.0 0.0 5.9 0.0 0.8 0.0 8.2 0.0 0.0 33.7 0.3 0.3 0.0 1.0 0.6 25.5 0.0 0.5 0.3 3.0 0.0 0.0 0.0 4.8 0.0 0.1 0.2 1.6 0.0 0.1 0.3 2.1 1.7 0.0 0.0 0.0 0.0 0.0 0.1 1.9 COL25A1 ENSG00000188517 "Collagen type XXV alpha 1 chain" Q9BXS0 4 108808725-109302752 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Heparin-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.0;retina: 24.7;testis: 19.1" "Cell type enhanced" "Detected in some" "Early spermatids: 107.1;Inhibitory neurons: 275.3;Late spermatids: 39.2;Rod photoreceptor cells: 71.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "HeLa: 47.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029107 Approved "Endoplasmic reticulum,Vesicles,Cytosol" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Cytosol" "Endoplasmic reticulum" "HPA029107: AB_10600802" "unprognostic (1.77e-1)" "unprognostic (2.12e-1)" "unprognostic (1.18e-1)" "unprognostic (8.87e-5)" "unprognostic (2.43e-2)" "unprognostic (3.20e-1)" "unprognostic (7.62e-3)" "unprognostic (6.86e-2)" "unprognostic (2.83e-1)" "unprognostic (3.53e-1)" "unprognostic (1.50e-2)" "unprognostic (1.17e-1)" "unprognostic (5.30e-3)" "unprognostic (2.82e-3)" "unprognostic (9.75e-2)" "unprognostic (1.31e-1)" "unprognostic (1.96e-1)" 6.1 0.5 13.4 0.1 10.3 0.0 2.8 0.0 30.0 1.1 0.3 0.4 2.9 0.6 1.6 0.4 0.9 2.2 0.5 17.8 13.7 1.9 2.2 0.2 0.1 6.5 9.4 1.0 0.2 1.3 7.0 0.3 1.0 0.5 0.3 24.7 4.9 0.5 1.0 0.7 2.5 0.8 6.9 0.8 0.3 19.1 8.9 0.5 2.8 0.3 0.1 0.7 1.0 1.7 0.0 0.0 5.3 0.0 0.0 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 2.7 0.0 0.1 0.0 3.2 5.9 47.6 0.0 0.0 0.0 0.0 3.3 0.0 0.2 0.0 0.2 0.0 0.1 1.2 0.2 5.6 0.0 0.8 0.0 1.6 0.0 0.1 0.0 2.6 0.0 0.0 0.0 1.1 0.0 0.0 0.2 1.4 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.8 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 10.3 0.0 30.0 17.8 13.7 6.5 9.4 1.0 6.9 8.9 1.7 8.2 0.0 0.0 12.4 0.1 0.0 0.1 0.0 2.2 2.1 0.4 0.6 1.0 0.0 0.6 1.8 4.2 0.0 0.0 0.0 0.0 0.0 107.1 6.5 2.0 1.6 0.0 0.0 20.5 0.0 0.0 0.7 0.0 18.9 0.0 0.5 0.7 0.0 0.0 1.7 275.3 0.0 0.0 0.0 0.4 39.2 0.6 0.2 0.0 10.3 0.0 2.8 0.0 16.6 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 71.5 0.0 4.7 24.6 7.8 1.6 0.0 0.1 0.0 0.1 0.3 0.0 0.0 COL26A1 "EMI6, EMID2, Emu2" ENSG00000160963 "Collagen type XXVI alpha 1 chain" Q96A83 7 101362875-101559024 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.8;liver: 5.5" "Group enriched" "Detected in some" 7 "Excitatory neurons: 68.4;Inhibitory neurons: 18.5" "Group enriched" "Detected in many" 6 "endometrial cancer: 12.6;ovarian cancer: 5.7;prostate cancer: 4.6;testis cancer: 14.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 45 "plasmacytoid DC: 9.2" "Lineage enriched" "Detected in single" 45 "dendritic cells: 9.2" "Cell line enhanced" "Detected in some" "AF22: 30.0;BEWO: 23.9;HAP1: 10.7;NTERA-2: 25.4;SuSa: 19.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA027059 Approved Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA027059: AB_1848142" "unprognostic (5.94e-3)" "unprognostic (2.16e-2)" "unprognostic (2.19e-2)" "unprognostic (4.67e-2)" "unprognostic (1.66e-1)" "unprognostic (3.35e-1)" "prognostic favorable (2.32e-5)" "unprognostic (1.48e-1)" "unprognostic (1.16e-1)" "unprognostic (2.85e-2)" "unprognostic (1.26e-3)" "unprognostic (1.78e-1)" "unprognostic (4.24e-3)" "unprognostic (3.60e-1)" "unprognostic (1.50e-1)" "unprognostic (7.48e-4)" "unprognostic (2.83e-3)" 0.1 4.4 5.2 0.1 7.4 0.2 0.1 0.2 12.8 0.2 0.2 0.0 0.0 0.3 0.1 0.0 0.3 0.1 0.0 9.8 1.2 4.9 5.5 0.4 0.5 1.1 0.9 0.4 2.2 3.9 0.9 0.3 0.9 2.2 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.4 0.2 0.3 1.0 2.0 1.2 0.1 0.0 0.1 0.2 0.1 4.2 0.0 0.8 30.0 1.9 0.0 0.0 23.9 0.0 0.0 0.0 0.0 1.3 0.0 0.1 4.7 0.0 0.1 0.0 10.7 0.0 0.0 1.0 1.3 0.0 0.0 7.9 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 25.4 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.6 0.0 0.0 0.2 19.2 0.3 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 5.2 7.4 0.2 12.8 9.8 1.2 1.1 0.9 0.9 0.4 2.0 4.2 0.0 0.0 0.0 3.3 0.7 0.0 0.3 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.0 5.5 0.0 0.3 0.0 0.0 0.0 0.2 1.5 0.1 1.7 0.1 0.0 0.0 68.4 0.6 0.4 0.5 0.0 0.2 0.0 1.0 0.0 3.6 0.1 0.0 18.5 0.0 0.0 0.0 0.0 3.5 0.0 0.5 0.0 5.6 0.0 0.0 0.0 3.5 2.1 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 2.0 0.0 0.0 0.4 0.0 0.9 0.0 0.4 COL4A2 "DKFZp686I14213, FLJ22259" ENSG00000134871 "Collagen type IV alpha 2 chain" P08572 13 110305812-110513209 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 474.0" "Cell type enhanced" "Detected in many" "Adipocytes: 313.6;Endometrial stromal cells: 308.3;Endothelial cells: 278.2;Extravillous trophoblasts: 512.9;Granulosa cells: 223.8;Sertoli cells: 374.7;Smooth muscle cells: 338.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 1041.3;WM-115: 428.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010751, HPA029118, HPA069337" Enhanced Supported Vesicles "Secreted to extracellular matrix" NA NA 2700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB010751: AB_476828, HPA029118: , HPA069337: " "unprognostic (2.43e-1)" "unprognostic (4.13e-3)" "unprognostic (8.04e-2)" "unprognostic (6.03e-3)" "unprognostic (2.20e-1)" "unprognostic (2.64e-2)" "unprognostic (3.45e-2)" "unprognostic (1.15e-2)" "unprognostic (3.50e-2)" "unprognostic (1.78e-1)" "unprognostic (1.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.49e-5)" "unprognostic (1.33e-2)" "unprognostic (1.57e-2)" "unprognostic (6.95e-2)" "prognostic unfavorable (9.25e-4)" 240.5 51.2 15.1 103.5 2.3 0.6 153.5 1.7 5.9 111.6 3.4 282.0 29.5 219.4 10.4 51.8 122.9 84.2 113.0 19.3 1.8 71.7 19.1 181.7 22.8 4.3 7.8 51.9 32.6 25.6 17.5 474.0 6.0 121.3 18.9 2.8 35.0 95.8 44.7 45.2 84.1 226.8 2.6 121.5 96.4 15.7 11.5 7.9 74.9 21.5 7.1 186.2 74.4 2.9 88.9 45.7 218.7 0.6 213.7 99.0 312.8 307.9 97.4 167.3 76.1 2.5 0.7 0.6 1041.3 60.0 75.0 85.4 0.1 82.4 27.3 28.1 46.3 0.2 76.6 0.7 150.5 0.5 1.0 42.8 4.5 114.8 71.2 193.5 158.5 0.0 1.3 0.9 25.4 0.3 0.3 12.1 34.2 0.8 11.7 0.6 87.8 0.4 125.6 0.0 6.4 35.4 0.3 0.9 81.2 84.7 0.6 6.7 327.7 94.9 237.9 2.3 161.9 0.6 3.0 7.4 5.8 0.4 428.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.1 2.3 1.7 5.9 19.3 1.8 4.3 7.8 6.0 2.6 11.5 2.9 313.6 83.3 5.8 17.9 2.9 9.6 8.0 16.3 1.8 2.4 7.0 56.8 31.8 20.0 1.8 53.3 0.0 77.4 0.1 10.0 1.9 39.0 1.7 19.4 308.3 278.2 0.0 8.0 17.7 4.4 512.9 159.1 5.6 50.1 1.3 223.8 102.1 1.8 30.9 0.0 44.0 7.0 2.0 3.3 13.3 3.4 60.6 3.8 39.2 46.9 2.0 7.3 0.0 5.5 1.1 2.8 1.4 176.0 1.5 12.3 23.9 32.7 2.1 0.3 374.7 64.7 338.9 0.9 8.5 0.7 7.0 67.2 3.6 49.4 5.4 2.4 COL4A3 ENSG00000169031 "Collagen type IV alpha 3 chain" Q01955 2 227164624-227314792 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 52.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 169.9;Bipolar cells: 62.1;Cone photoreceptor cells: 398.2;Muller glia cells: 143.1;Oligodendrocyte precursor cells: 84.9" "Group enriched" "Detected in some" 6 "lung cancer: 1.7;renal cancer: 3.0;thyroid cancer: 5.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.0" "Lineage enriched" "Detected in single" 7 "B-cells: 1.0" "Cell line enhanced" "Detected in some" "HeLa: 18.8;hTERT-RPE1: 14.5;Karpas-707: 9.9;RPTEC TERT1: 11.0;U-266/70: 9.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042064 Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Endoplasmic reticulum" "HPA042064: AB_10794410" "unprognostic (4.81e-2)" "unprognostic (2.25e-1)" "unprognostic (2.23e-1)" "unprognostic (9.28e-6)" "unprognostic (1.43e-1)" "unprognostic (3.29e-2)" "unprognostic (1.84e-2)" "unprognostic (7.07e-3)" "unprognostic (2.30e-1)" "unprognostic (9.09e-3)" "unprognostic (9.30e-2)" "unprognostic (3.02e-2)" "prognostic favorable (2.51e-7)" "unprognostic (1.78e-1)" "unprognostic (3.10e-2)" "unprognostic (2.49e-2)" "unprognostic (1.26e-1)" 0.6 11.5 1.9 2.1 1.8 0.3 1.0 1.5 1.7 0.4 21.5 0.8 0.7 1.2 16.3 1.0 2.1 3.2 8.9 1.4 2.0 30.5 0.6 15.0 2.9 3.3 3.1 3.9 5.0 0.2 16.2 0.2 2.7 6.0 1.0 52.9 1.2 9.9 22.2 0.5 6.7 0.8 1.6 7.2 1.8 1.7 6.3 0.4 20.5 15.2 5.6 1.4 1.2 2.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.8 0.0 0.0 0.3 1.1 0.1 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 0.0 1.2 0.0 9.9 0.0 0.4 0.0 0.1 1.4 0.0 0.0 0.1 0.0 3.2 11.0 2.3 0.5 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.1 9.0 3.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.8 1.5 1.7 1.4 2.0 3.3 3.1 2.7 1.6 6.3 2.2 0.5 169.9 31.7 3.9 14.0 0.1 0.1 0.1 0.6 62.1 0.1 0.9 2.6 1.5 9.3 42.3 398.2 0.1 0.1 0.0 0.0 0.1 0.7 0.1 0.2 2.4 0.0 0.0 5.5 1.0 0.0 4.6 0.5 0.3 1.3 22.8 0.4 0.2 0.0 1.7 14.1 0.0 0.0 0.0 0.3 0.3 8.4 0.3 1.8 13.1 0.0 143.1 0.0 84.9 3.6 1.0 0.0 12.0 8.0 0.1 0.0 1.9 0.1 11.9 13.1 11.7 3.6 0.4 0.0 0.3 0.3 0.0 1.2 0.1 0.0 0.0 COL4A5 "ASLN, ATS" ENSG00000188153 "Collagen type IV alpha 5 chain" P29400 X 108439838-108697545 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 102.9" "Cell type enriched" "Detected in many" 9 "Oligodendrocytes: 713.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 87.7;HHSteC: 95.0;HUVEC TERT2: 92.8;TIME: 88.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077177 Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Vesicles "HPA077177: " "unprognostic (2.58e-2)" "unprognostic (2.57e-2)" "unprognostic (3.64e-2)" "unprognostic (3.98e-2)" "unprognostic (1.11e-1)" "unprognostic (1.61e-1)" "unprognostic (1.97e-2)" "unprognostic (7.27e-2)" "unprognostic (2.70e-1)" "unprognostic (2.20e-1)" "unprognostic (1.60e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.41e-5)" "unprognostic (2.10e-3)" "unprognostic (1.70e-1)" "unprognostic (2.61e-2)" "unprognostic (1.06e-1)" 7.4 5.6 25.2 2.3 57.4 0.0 8.1 38.2 40.8 38.1 20.0 5.8 3.8 59.2 25.4 9.6 37.5 18.2 10.9 27.0 33.7 16.9 2.4 8.5 1.2 47.7 43.1 23.0 3.8 16.8 19.7 14.5 47.4 37.0 5.6 6.1 7.4 32.9 7.6 26.4 6.3 47.2 36.4 5.5 34.5 6.0 45.3 2.7 10.5 4.4 1.0 47.6 22.7 102.9 4.5 26.7 47.2 14.9 18.0 10.6 0.3 2.8 11.7 14.2 23.2 24.0 1.9 4.2 0.0 2.0 8.6 21.7 13.2 45.2 17.8 6.7 11.7 3.4 87.7 2.9 95.0 0.0 13.5 49.2 53.6 17.4 37.2 45.2 92.8 0.0 0.2 0.1 13.9 2.0 0.1 0.5 14.0 0.0 16.0 0.1 0.0 0.2 35.9 26.7 0.0 0.0 70.2 2.2 6.0 65.6 12.9 0.0 88.8 9.5 2.8 6.4 4.0 1.9 0.0 0.0 8.2 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.2 57.4 38.2 40.8 27.0 33.7 47.7 43.1 47.4 36.4 45.3 102.9 1.0 6.4 7.3 72.5 0.0 26.9 29.7 29.4 17.1 0.5 14.8 14.7 10.0 2.8 14.2 20.2 0.0 0.7 0.0 0.0 0.0 0.4 0.1 7.4 45.4 4.6 0.0 0.0 1.1 0.9 0.4 12.3 3.1 5.7 1.3 2.0 4.2 0.5 0.4 0.0 1.5 0.2 6.1 0.3 2.1 1.7 20.2 0.6 1.8 20.6 0.0 11.1 0.0 3.5 713.9 0.4 0.0 36.9 0.0 18.1 0.0 0.1 8.2 0.6 6.6 2.4 18.3 0.4 0.9 4.2 15.9 0.7 1.1 21.5 0.1 24.7 COL5A1 ENSG00000130635 "Collagen type V alpha 1 chain" P20908 9 134641803-134844843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Cancer-related genes, Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 146.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 141.1;Fibroblasts: 134.9;Leydig cells: 61.2;Sertoli cells: 52.6;Skeletal myocytes: 78.3;Smooth muscle cells: 57.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 446.6;fHDF/TERT166: 414.6;HeLa: 297.0;HHSteC: 265.8;SiHa: 290.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030769 Approved Approved Vesicles "Secreted to extracellular matrix" No No 15000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA030769: AB_2673603" "unprognostic (7.77e-2)" "unprognostic (4.55e-3)" "unprognostic (2.22e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (9.56e-4)" "unprognostic (8.07e-2)" "unprognostic (8.09e-2)" "unprognostic (2.38e-3)" "unprognostic (1.54e-2)" "unprognostic (5.03e-3)" "unprognostic (5.05e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (2.07e-12)" "unprognostic (2.02e-2)" "unprognostic (4.73e-2)" "unprognostic (1.65e-2)" "unprognostic (2.50e-3)" 39.3 12.0 1.3 39.1 1.5 1.0 20.0 1.9 2.7 146.6 3.4 72.0 13.5 118.2 11.1 23.2 59.6 77.6 32.8 1.2 1.9 11.5 7.6 35.7 5.5 4.0 2.5 51.9 7.0 6.8 6.6 95.8 1.3 43.8 16.3 3.1 9.3 28.9 10.2 24.6 22.0 89.6 1.8 17.6 31.4 6.2 4.6 2.3 10.1 7.3 2.9 51.6 63.4 1.4 0.6 16.7 13.0 20.7 192.2 202.4 7.9 446.6 89.0 73.6 78.6 0.2 0.3 0.0 95.3 414.6 39.8 5.6 0.0 0.1 21.3 0.1 1.0 0.3 297.0 0.1 265.8 0.2 2.7 200.0 0.2 71.1 5.6 0.0 89.2 0.1 0.1 1.2 39.5 4.1 0.3 0.9 7.6 0.0 8.5 15.7 50.3 1.8 0.1 0.1 5.3 2.5 290.0 1.8 0.2 173.7 0.6 0.2 152.6 154.4 61.9 190.4 93.7 0.3 0.2 0.4 121.6 0.1 26.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.5 1.9 2.7 1.2 1.9 4.0 2.5 1.3 1.8 4.6 1.4 7.9 0.0 1.8 0.7 0.3 14.5 3.5 0.8 3.4 8.5 0.8 2.7 9.0 0.0 0.0 1.8 2.1 6.4 0.3 0.0 1.9 2.2 5.5 4.2 141.1 8.8 0.0 0.0 6.6 0.0 12.3 134.9 1.5 4.8 0.0 1.2 21.8 0.0 8.9 0.0 1.2 0.0 0.0 0.3 15.3 15.6 61.2 1.5 7.2 12.2 0.0 6.4 0.0 5.5 0.3 1.3 0.0 38.7 0.3 1.0 0.0 0.3 0.0 1.2 52.6 78.3 57.5 0.5 0.8 0.6 7.7 10.4 2.6 11.7 0.0 0.4 COL6A3 ENSG00000163359 "Collagen type VI alpha 3 chain" P12111 2 237324003-237414207 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Congenital muscular dystrophy, Disease variant, Dystonia, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 391.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 355.2;Fibroblasts: 567.9;Leydig cells: 315.1;Smooth muscle cells: 197.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 3311.7;ASC TERT1: 4227.5;BJ hTERT+: 1279.6;HSkMC: 2705.3" "Region enhanced" "Detected in some" "basal ganglia: 4.5" "Region enriched" "Detected in many" 4 "spinal cord: 12.0" "HPA010007, HPA010080" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 1000000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA010007: , HPA010080: AB_1078550" "unprognostic (8.94e-2)" "unprognostic (7.24e-2)" "unprognostic (6.60e-2)" "unprognostic (3.82e-1)" "unprognostic (3.90e-2)" "unprognostic (2.37e-1)" "unprognostic (5.34e-2)" "unprognostic (2.87e-2)" "unprognostic (8.20e-3)" "unprognostic (2.55e-2)" "unprognostic (1.33e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (5.57e-11)" "unprognostic (1.54e-2)" "unprognostic (2.50e-2)" "unprognostic (3.51e-2)" "unprognostic (1.84e-3)" 150.8 8.3 0.1 126.5 1.0 0.4 74.5 0.2 3.0 212.6 5.2 94.8 22.9 156.3 10.2 44.1 91.8 236.4 61.2 2.4 0.1 5.7 10.3 65.8 30.7 0.6 0.1 123.8 21.1 17.3 2.8 132.9 0.7 47.7 51.7 0.0 45.2 55.4 32.5 35.7 46.6 391.3 0.8 19.0 41.5 15.6 1.8 24.8 38.1 62.3 16.1 188.4 62.7 0.9 0.2 0.5 0.6 0.0 3311.7 4227.5 60.9 815.6 1279.6 167.0 188.2 0.0 0.1 4.5 0.1 818.7 67.4 0.6 0.7 0.9 98.8 2.0 0.1 0.0 0.0 0.0 669.9 0.0 0.4 2705.3 0.0 596.3 1.8 7.8 0.2 0.0 0.1 0.6 6.2 0.0 0.1 0.2 0.5 0.0 7.4 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.4 17.3 0.0 0.4 2.9 19.0 45.1 27.6 142.4 1.0 0.0 0.1 859.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.2 3.0 2.4 0.1 0.6 0.1 0.7 0.8 1.8 0.9 48.2 0.0 10.5 0.3 0.6 61.1 0.5 0.5 1.8 1.0 2.5 2.9 10.6 1.5 3.8 0.0 0.0 4.5 1.2 0.0 0.0 0.9 5.4 11.0 355.2 17.6 0.0 0.0 0.8 0.0 6.2 567.9 6.6 8.7 1.3 1.8 25.4 1.8 8.1 0.0 0.4 0.0 0.0 1.3 85.4 9.6 315.1 5.5 72.9 29.0 2.2 1.1 1.0 0.0 0.3 2.4 0.0 103.4 2.0 0.9 0.0 0.2 1.0 2.3 32.9 19.2 197.7 1.5 1.3 3.3 61.5 5.7 9.3 48.7 0.0 1.0 COL7A1 "EBD1, EBDCT, EBR1" ENSG00000114270 "Collagen type VII alpha 1 chain" Q02388 3 48564073-48595329 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 98.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 72.5;Basal respiratory cells: 59.3;Basal squamous epithelial cells: 67.2;Endometrial stromal cells: 45.3" "Cancer enhanced" "Detected in all" "head and neck cancer: 41.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 65.7;HaCaT: 63.5;HBEC3-KT: 100.6;HDLM-2: 97.8;HeLa: 146.2;SiHa: 82.8" "CAB016357, HPA018877, HPA042420" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 6000 "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" Vesicles "CAB016357: AB_2229746, HPA018877: , HPA042420: AB_2677990" "unprognostic (2.69e-2)" "unprognostic (4.11e-1)" "unprognostic (1.35e-1)" "unprognostic (3.47e-1)" "unprognostic (4.93e-2)" "prognostic favorable (6.31e-4)" "unprognostic (7.56e-2)" "unprognostic (1.25e-2)" "unprognostic (5.59e-2)" "unprognostic (2.98e-1)" "prognostic unfavorable (3.86e-4)" "unprognostic (3.74e-2)" "unprognostic (0.00e+0)" "unprognostic (1.76e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (3.86e-2)" 0.8 1.1 1.4 3.8 1.0 0.1 4.9 2.8 2.1 24.3 0.4 2.9 1.7 12.1 6.7 21.8 6.4 4.0 3.2 0.3 6.5 7.4 1.3 1.7 1.2 7.0 3.2 3.4 0.4 0.0 2.5 1.6 3.0 34.2 0.9 1.4 11.5 12.2 3.5 98.2 4.1 2.5 2.6 6.5 2.1 3.6 6.5 1.2 0.5 0.6 1.3 6.6 29.2 0.6 0.2 25.4 1.2 0.5 9.2 12.3 31.0 65.7 40.8 16.9 10.0 0.4 0.5 0.1 2.0 15.0 15.4 63.5 0.0 100.6 3.1 97.8 0.5 0.2 146.2 4.3 25.6 0.0 0.4 19.9 58.8 34.4 26.8 23.1 0.0 0.7 0.5 0.7 2.0 0.3 0.0 0.9 3.1 1.3 1.3 0.5 2.2 0.2 9.2 0.2 0.2 0.2 82.8 0.1 0.8 3.7 1.3 0.3 0.0 5.6 3.2 3.2 50.1 1.8 1.8 0.1 49.0 0.4 2.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.0 2.8 2.1 0.3 6.5 7.0 3.2 3.0 2.6 6.5 0.6 0.4 0.0 0.0 10.7 0.2 72.5 24.1 59.3 67.2 17.7 1.0 10.2 6.6 0.0 10.6 11.0 10.4 1.4 0.1 0.6 0.0 0.9 11.8 3.1 45.3 1.4 1.8 0.0 6.8 0.7 1.0 8.3 1.1 4.0 0.0 0.8 0.4 0.7 1.6 8.4 11.6 0.7 0.0 0.3 4.2 6.3 5.0 0.8 8.8 8.4 0.1 2.6 0.0 4.0 4.4 15.6 0.1 5.7 0.0 5.7 0.2 0.3 2.5 12.9 0.0 2.0 13.4 2.6 1.5 11.3 24.2 1.2 0.8 5.0 0.2 5.8 COL8A1 "C3orf7, MGC9568" ENSG00000144810 "Collagen type VIII alpha 1 chain" P27658 3 99638475-99799226 "Plasma proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 246.8;Fibroblasts: 53.3;Hepatic stellate cells: 102.8;Smooth muscle cells: 51.6" "Cancer enhanced" "Detected in all" "thyroid cancer: 34.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 1098.3;hTERT-RPE1: 431.9;LHCN-M2: 313.0;TIME: 471.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA053107 Enhanced Supported Vesicles "Secreted to extracellular matrix" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA053107: AB_2682046" "unprognostic (3.13e-2)" "unprognostic (2.92e-2)" "unprognostic (2.27e-2)" "unprognostic (1.37e-1)" "unprognostic (2.07e-3)" "unprognostic (2.49e-1)" "unprognostic (2.31e-2)" "unprognostic (4.83e-2)" "unprognostic (2.62e-2)" "unprognostic (4.79e-2)" "unprognostic (3.58e-2)" "unprognostic (3.71e-1)" "prognostic unfavorable (9.39e-8)" "unprognostic (2.98e-3)" "unprognostic (1.72e-1)" "unprognostic (1.38e-2)" "unprognostic (1.32e-3)" 33.0 7.0 1.7 5.8 2.9 0.0 5.7 1.8 2.6 3.8 4.4 12.4 1.0 5.2 2.7 11.1 9.1 10.8 39.1 1.3 3.0 5.9 0.9 32.8 0.9 3.1 3.9 9.2 1.2 17.9 11.3 4.2 3.4 12.7 6.9 0.5 7.0 12.0 2.3 3.2 3.7 31.5 2.7 1.0 5.3 0.5 2.6 0.4 27.5 7.8 0.5 25.0 5.4 2.5 0.1 0.4 3.0 0.3 142.2 236.4 0.2 68.5 45.7 69.6 138.6 0.0 0.3 0.1 5.9 1098.3 1.9 0.1 0.4 88.2 157.8 0.1 0.2 0.1 7.9 0.0 26.8 0.0 0.1 142.8 3.2 52.6 82.9 431.9 129.4 0.0 0.1 0.2 313.0 0.0 0.0 0.0 2.6 0.0 0.9 0.0 0.0 0.0 144.3 0.0 0.0 0.0 0.0 0.0 0.0 20.8 0.1 0.2 471.5 31.0 24.1 1.6 34.2 0.1 0.0 0.1 58.4 0.0 241.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.9 1.8 2.6 1.3 3.0 3.1 3.9 3.4 2.7 2.6 2.5 4.4 246.8 22.1 0.0 0.4 0.8 0.5 2.8 14.8 0.4 1.8 5.2 4.9 4.3 3.9 9.2 0.0 0.1 0.9 0.0 0.0 0.1 1.3 0.2 2.6 14.1 0.0 0.0 1.9 0.0 0.3 53.3 2.0 0.3 5.1 0.2 102.8 0.8 0.1 0.0 0.7 0.0 0.0 1.9 2.3 1.0 2.1 0.8 1.8 4.7 0.2 0.7 2.1 9.0 0.6 0.1 0.0 9.4 0.5 0.2 0.0 1.6 1.0 0.6 0.0 1.9 51.6 0.3 0.3 1.0 0.6 0.4 0.9 0.1 0.0 0.5 COL9A2 "EDM2, MED" ENSG00000049089 "Collagen type IX alpha 2 chain" Q14055 1 40300489-40317813 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Deafness, Disease variant, Dwarfism, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 86.2;pituitary gland: 108.1" "Cell type enhanced" "Detected in many" "Muller glia cells: 295.4;Oligodendrocyte precursor cells: 62.4;Oligodendrocytes: 128.1" "Cancer enhanced" "Detected in all" "prostate cancer: 68.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 3.2;myeloid DC: 1.2" "Group enriched" "Detected in many" 6 "dendritic cells: 1.2;granulocytes: 3.2" "Group enriched" "Detected in many" 4 "HDLM-2: 98.6;Hep G2: 27.6;HMC-1: 90.3;THP-1: 105.0" "Low region specificity" "Detected in all" "HPA056316, HPA075286" Supported Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" NA NA 510000 "Cluster 52: Eosinophils - Transcription" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 5: Muller glia cells - Visual perception" Vesicles Nucleoplasm "HPA056316: AB_2683099, HPA075286: AB_2732288" "unprognostic (1.42e-2)" "unprognostic (3.54e-2)" "unprognostic (8.94e-2)" "prognostic unfavorable (5.13e-4)" "unprognostic (4.46e-2)" "unprognostic (1.83e-3)" "unprognostic (2.06e-2)" "unprognostic (9.00e-3)" "unprognostic (1.73e-1)" "unprognostic (1.26e-1)" "unprognostic (1.56e-3)" "unprognostic (2.26e-1)" "unprognostic (1.16e-3)" "unprognostic (4.28e-2)" "unprognostic (2.56e-1)" "unprognostic (5.89e-2)" "unprognostic (1.71e-2)" 2.2 3.4 42.6 3.7 71.5 10.9 5.9 58.9 51.1 12.1 21.6 6.5 5.8 5.0 1.7 1.6 11.4 8.5 2.2 38.2 49.7 24.6 0.9 4.3 5.9 65.9 74.1 1.3 2.3 21.0 108.1 1.1 66.2 13.7 3.1 23.1 16.3 24.2 0.2 4.6 10.4 1.4 52.0 9.8 16.5 2.6 58.6 1.8 12.2 0.3 3.1 12.1 2.0 86.2 12.0 0.3 1.8 0.8 2.6 1.3 7.8 0.0 0.0 0.6 1.3 0.4 6.8 3.4 10.0 0.3 0.0 2.0 0.1 0.0 0.3 98.6 1.4 2.0 0.8 27.6 1.5 0.9 90.3 4.8 0.0 0.1 0.0 0.7 0.0 1.5 0.1 19.8 0.0 2.7 1.2 2.1 2.2 0.0 1.2 2.3 0.0 6.9 0.0 14.3 1.4 2.3 0.1 11.8 1.3 6.6 15.0 105.0 0.1 0.0 11.6 0.2 0.4 1.4 0.2 3.4 1.0 12.3 0.6 0.0 0.1 3.2 0.0 0.2 0.0 0.2 0.1 0.0 1.2 0.2 0.0 0.0 0.5 0.2 0.3 0.1 0.1 0.0 42.6 71.5 58.9 51.1 38.2 49.7 65.9 74.1 66.2 52.0 58.6 86.2 0.5 0.0 3.3 26.1 10.8 1.0 3.0 8.5 0.0 2.0 7.1 9.7 1.0 7.2 10.0 25.8 0.0 3.2 2.5 7.2 0.0 11.7 0.2 13.6 0.9 0.6 12.7 0.4 0.3 0.8 0.6 2.1 26.0 20.0 26.1 1.6 1.1 0.0 3.4 0.0 0.3 6.6 2.0 0.3 22.4 0.9 2.1 6.4 1.8 3.7 22.1 295.4 1.0 62.4 128.1 4.9 9.6 0.0 4.0 6.1 5.0 0.3 12.9 10.9 0.0 1.3 1.8 3.4 6.2 0.2 0.6 1.4 2.7 1.8 13.4 13.4 COLEC12 "CL-P1, SCARA4, SRCL" ENSG00000158270 "Collectin subfamily member 12" Q5KU26 18 316737-500722 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 31.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 104.4;Cytotrophoblasts: 149.0;Fibroblasts: 79.6;Hofbauer cells: 155.9;Microglial cells: 245.4;Muller glia cells: 74.5;Syncytiotrophoblasts: 111.2" "Cancer enhanced" "Detected in all" "prostate cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 24.3;BJ: 12.1;HSkMC: 20.0;U-2197: 31.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047917, HPA071056" Enhanced Approved "Golgi apparatus,Vesicles,Cell Junctions" NA NA 580000 "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "Cell Junctions" "HPA047917: AB_2680208, HPA071056: AB_2686338" "unprognostic (8.67e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (3.60e-2)" "unprognostic (6.94e-2)" "unprognostic (1.09e-2)" "unprognostic (1.14e-4)" "unprognostic (2.21e-1)" "unprognostic (1.21e-1)" "unprognostic (4.86e-2)" "unprognostic (1.32e-2)" "unprognostic (1.53e-1)" "unprognostic (2.61e-1)" "unprognostic (2.24e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (3.01e-3)" 12.4 1.7 5.1 2.4 4.8 0.2 5.5 4.7 5.7 31.6 9.7 5.5 1.5 9.0 1.0 2.0 6.5 4.4 6.6 4.6 7.2 2.4 0.3 11.4 2.0 7.7 6.5 2.0 1.1 0.9 0.9 20.0 5.2 4.0 2.4 5.3 4.1 1.4 3.1 3.6 3.5 5.1 4.3 0.3 3.4 1.4 6.5 1.3 5.2 2.0 2.5 8.1 4.0 5.5 0.0 0.0 2.1 0.0 2.3 24.3 0.8 12.1 4.2 1.7 3.1 0.0 0.0 0.0 0.1 2.0 0.1 0.0 0.3 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.1 0.0 0.0 20.0 0.0 1.0 0.0 0.7 4.7 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.7 0.0 6.5 0.0 0.0 0.1 0.3 0.0 0.1 0.0 1.9 0.1 0.0 0.0 2.8 0.4 31.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.1 0.1 0.0 0.0 5.1 4.8 4.7 5.7 4.6 7.2 7.7 6.5 5.2 4.3 6.5 5.5 6.8 3.2 104.4 34.3 2.1 4.1 3.2 0.0 1.2 6.4 2.6 1.7 4.0 2.8 10.7 3.7 10.4 149.0 1.4 0.3 0.0 0.2 11.1 0.5 3.9 15.8 15.7 2.7 0.5 0.0 5.3 79.6 0.0 0.8 13.9 1.2 5.7 0.4 155.9 6.7 1.4 1.0 0.0 4.9 8.9 31.4 61.5 32.1 1.8 245.4 16.2 74.5 3.1 2.0 10.4 0.3 0.6 7.2 1.2 6.5 1.4 0.2 1.7 12.4 0.0 13.2 21.6 1.3 2.5 1.8 3.8 111.2 4.8 11.6 0.8 1.3 COLGALT1 "FLJ22329, GLT25D1" ENSG00000130309 "Collagen beta(1-O)galactosyltransferase 1" Q8NBJ5 19 17555649-17583162 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 76.2;Hofbauer cells: 91.0;Kupffer cells: 70.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047821 Approved Approved Vesicles "Intracellular and membrane" No No 9700 "Cluster 7: Monocytes - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA047821: AB_2680168" "unprognostic (2.46e-1)" "unprognostic (1.16e-1)" "unprognostic (3.49e-1)" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.65e-5)" "unprognostic (2.92e-3)" "unprognostic (2.92e-1)" "unprognostic (1.66e-3)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.89e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.43e-2)" "unprognostic (1.09e-1)" "unprognostic (8.87e-2)" "prognostic unfavorable (3.83e-4)" 38.6 14.3 5.9 38.1 6.9 32.9 27.5 7.9 8.4 31.1 10.6 27.7 16.2 28.4 4.4 17.9 26.5 19.0 22.4 7.1 9.1 12.7 16.3 34.9 29.7 12.1 9.3 23.5 15.8 9.0 10.1 40.9 12.3 15.5 15.2 3.2 15.9 16.3 15.1 23.9 24.7 35.4 7.6 39.5 18.2 11.9 18.9 9.9 14.7 7.5 15.8 28.1 22.8 12.6 103.1 118.0 56.7 79.8 222.3 136.3 90.9 95.9 55.1 121.8 125.9 90.4 159.6 53.0 164.7 166.9 104.2 91.5 58.4 110.6 73.4 29.5 94.9 51.2 147.4 87.9 121.6 123.0 147.8 115.2 97.6 136.7 56.7 49.7 138.8 33.3 105.5 25.8 45.1 45.6 61.9 81.1 43.0 75.8 115.3 65.2 73.8 80.9 26.4 67.2 41.2 29.9 102.8 80.6 97.0 36.7 41.9 177.7 98.7 240.8 67.7 215.3 156.2 45.4 125.1 58.3 142.7 232.4 113.0 1.7 25.7 12.5 5.2 28.1 2.8 3.5 4.8 4.9 18.1 3.3 3.4 5.3 3.6 2.1 20.8 7.0 3.1 14.5 5.9 6.9 7.9 8.4 7.1 9.1 12.1 9.3 12.3 7.6 18.9 12.6 35.0 19.2 23.5 11.1 10.3 19.5 7.0 10.4 10.8 3.7 8.8 9.5 11.2 10.0 15.5 11.0 6.2 7.9 28.6 14.7 0.0 13.1 3.6 8.5 28.5 29.3 5.4 10.3 10.9 8.2 76.2 30.9 20.9 13.6 8.8 20.3 7.9 14.2 91.0 13.5 9.9 15.1 4.1 70.7 24.1 3.1 19.0 59.6 17.8 19.7 26.6 2.3 10.3 6.6 12.8 10.4 7.6 21.8 6.0 9.5 9.5 4.4 8.7 3.6 13.1 9.5 24.3 2.5 13.1 13.8 20.9 8.3 12.0 24.9 18.2 8.4 COLGALT2 "C1orf17, GLT25D2, KIAA0584" ENSG00000198756 "Collagen beta(1-O)galactosyltransferase 2" Q8IYK4 1 183929854-184037729 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 50.6" "Cell type enhanced" "Detected in many" "Astrocytes: 53.5;Excitatory neurons: 79.9;Inhibitory neurons: 71.5;Late spermatids: 76.2;Oligodendrocyte precursor cells: 115.1;Oligodendrocytes: 359.3" "Cancer enhanced" "Detected in many" "glioma: 11.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 30 "basophil: 11.1" "Lineage enriched" "Detected in single" 30 "granulocytes: 11.1" "Cell line enhanced" "Detected in many" "Hep G2: 17.1;OE19: 13.8;SK-MEL-30: 18.6;U-251 MG: 18.0;WM-115: 22.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031749, HPA031750" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Vesicles "HPA031749: AB_10599298, HPA031750: AB_10611252" "unprognostic (5.44e-3)" "unprognostic (3.08e-1)" "unprognostic (6.29e-5)" "unprognostic (2.08e-1)" "unprognostic (4.41e-2)" "unprognostic (1.54e-1)" "unprognostic (1.16e-1)" "unprognostic (1.09e-2)" "unprognostic (2.52e-1)" "unprognostic (2.00e-1)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (5.13e-9)" "unprognostic (1.53e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-2)" "unprognostic (3.80e-2)" 1.7 6.4 15.7 0.8 29.3 1.1 1.5 22.7 18.6 1.0 0.0 4.3 0.5 1.8 3.1 0.7 2.8 2.3 11.4 16.5 17.3 0.8 0.2 3.7 0.3 26.8 24.0 1.3 2.3 0.5 2.2 0.1 28.7 5.3 0.9 3.5 2.9 2.2 8.8 0.3 1.0 1.7 20.2 0.5 1.9 3.5 25.8 0.3 3.3 6.3 0.5 1.8 1.5 50.6 0.1 0.0 5.7 0.4 3.0 4.4 0.1 1.8 0.7 0.8 1.0 2.8 0.2 0.0 0.5 4.4 1.1 0.0 5.6 0.0 1.4 6.6 3.3 0.4 0.0 17.1 0.1 6.0 0.1 2.6 0.0 0.8 0.1 8.4 0.0 0.2 5.7 7.2 6.1 0.2 0.3 0.3 3.9 13.8 0.0 0.5 0.0 0.0 0.0 1.2 2.2 3.5 0.3 0.0 18.6 3.7 0.0 0.3 0.1 0.7 0.7 0.1 18.0 10.8 0.1 0.1 0.5 2.8 22.5 11.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 15.7 29.3 22.7 18.6 16.5 17.3 26.8 24.0 28.7 20.2 25.8 50.6 0.1 0.0 0.0 53.5 0.0 0.4 0.5 0.0 0.0 4.4 0.3 0.3 3.5 0.0 0.0 0.0 0.0 0.1 4.1 0.0 0.0 0.6 40.3 0.2 0.5 0.9 0.0 1.3 79.9 0.0 0.0 9.9 1.5 0.5 0.0 0.2 0.0 0.1 0.3 0.0 71.5 0.1 0.0 0.3 9.5 76.2 2.1 0.9 1.8 4.7 0.0 5.7 8.2 115.1 359.3 1.2 0.0 4.1 1.9 0.2 0.0 0.3 0.0 0.4 13.1 2.3 3.1 0.3 1.3 0.0 0.4 0.0 4.5 0.4 0.0 0.4 COMMD4 FLJ20452 ENSG00000140365 "COMM domain containing 4" Q9H0A8 15 75336020-75343224 "Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039935, HPA066957" Uncertain Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Vesicles, Plasma membrane" "HPA039935: , HPA066957: AB_2685754" "unprognostic (7.77e-2)" "unprognostic (3.07e-3)" "unprognostic (1.03e-1)" "unprognostic (6.57e-3)" "unprognostic (1.32e-1)" "unprognostic (1.89e-1)" "unprognostic (1.49e-1)" "unprognostic (2.60e-1)" "unprognostic (9.11e-2)" "unprognostic (1.78e-3)" "unprognostic (2.01e-1)" "unprognostic (2.65e-1)" "unprognostic (1.39e-3)" "unprognostic (2.51e-1)" "unprognostic (2.27e-1)" "unprognostic (1.96e-1)" "unprognostic (5.07e-2)" 36.2 72.3 38.8 33.5 39.4 52.9 36.8 40.5 50.4 31.1 43.7 41.6 48.3 30.3 30.2 39.9 34.6 37.3 38.9 36.9 39.7 54.6 51.0 34.6 44.7 39.5 38.1 24.4 33.8 48.9 33.9 31.2 38.6 34.2 33.8 13.4 43.4 34.0 30.3 35.0 42.2 24.7 40.8 41.3 42.5 81.2 42.4 53.3 38.8 15.3 36.7 33.6 31.8 42.0 138.2 222.5 97.5 124.8 42.3 64.9 98.5 98.8 106.2 191.2 196.6 133.8 184.0 88.8 100.2 79.5 168.8 144.8 175.2 116.5 82.7 70.1 242.4 104.8 169.8 151.0 76.4 79.4 111.0 74.3 63.6 116.2 21.9 48.4 96.5 103.6 108.2 128.1 147.1 179.7 71.0 117.4 140.9 75.2 127.9 127.5 137.4 127.8 98.6 127.8 79.2 114.8 131.2 105.1 169.8 63.8 164.7 160.9 78.6 135.3 119.2 125.8 184.8 93.4 218.7 101.4 138.9 181.9 125.4 27.0 44.1 40.7 84.7 61.8 52.8 47.5 51.7 63.2 50.0 46.4 31.9 47.4 9.5 76.8 55.6 70.6 87.6 39.4 38.8 39.4 40.5 50.4 36.9 39.7 39.5 38.1 38.6 40.8 42.4 42.0 43.7 28.9 52.4 15.0 26.2 27.0 44.8 58.5 28.5 40.7 44.3 50.3 18.7 38.6 46.2 35.0 31.3 80.9 34.8 59.6 58.7 72.6 12.2 37.1 44.9 42.7 30.5 60.8 9.0 78.7 107.0 43.4 33.1 45.7 41.8 91.1 37.5 41.9 127.5 16.8 8.8 72.8 44.7 35.8 27.0 17.6 49.0 41.3 37.4 11.2 28.5 78.1 53.5 7.1 17.6 72.4 61.7 34.3 43.0 26.6 71.2 98.1 39.8 49.4 46.0 36.1 59.3 152.9 63.5 34.3 30.7 50.8 32.2 53.4 58.7 48.7 COMMD7 "C20orf92, dJ1085F17.3" ENSG00000149600 "COMM domain containing 7" Q86VX2 20 32702699-32743467 "Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 225.9;Syncytiotrophoblasts: 264.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-937: 331.1" "Low region specificity" "Detected in all" HPA054119 Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "HPA054119: AB_2682388" "unprognostic (1.27e-1)" "unprognostic (1.51e-1)" "unprognostic (1.65e-1)" "unprognostic (1.84e-1)" "unprognostic (9.90e-2)" "unprognostic (1.64e-2)" "prognostic unfavorable (1.46e-4)" "unprognostic (5.31e-2)" "unprognostic (8.92e-2)" "unprognostic (2.31e-1)" "unprognostic (6.57e-2)" "unprognostic (2.98e-1)" "unprognostic (2.90e-3)" "unprognostic (5.04e-2)" "unprognostic (8.28e-2)" "unprognostic (8.52e-2)" "prognostic favorable (3.53e-4)" 34.6 38.7 60.2 23.0 62.5 40.5 36.6 59.3 87.1 27.9 58.6 41.4 18.1 29.1 49.1 27.2 27.3 25.7 61.7 62.2 59.7 52.7 44.5 29.4 29.9 59.4 62.5 24.1 36.7 40.7 17.7 38.5 59.1 35.6 30.3 24.7 31.7 31.2 66.4 37.1 26.4 33.2 58.9 36.8 36.0 11.5 61.9 25.8 49.7 54.4 34.0 38.3 28.3 58.8 69.9 45.2 43.6 30.9 32.4 58.7 80.3 59.8 96.8 96.4 66.0 88.0 44.0 55.3 51.1 71.4 80.3 30.6 38.0 49.7 72.0 22.3 25.2 154.8 25.3 65.6 83.6 63.5 84.2 45.6 61.1 73.9 43.3 76.1 95.9 30.1 55.8 26.7 62.4 51.4 55.4 133.2 37.4 68.6 43.9 51.4 4.2 19.0 103.2 46.6 26.8 41.3 59.1 81.6 101.3 47.5 48.3 101.6 65.3 97.3 54.0 61.8 61.3 29.8 25.6 18.6 119.0 331.1 39.6 116.9 105.8 162.7 76.5 144.0 67.7 63.5 61.4 70.9 122.7 61.2 67.7 64.6 10.4 99.9 165.2 82.2 75.1 166.2 60.2 62.5 59.3 87.1 62.2 59.7 59.4 62.5 59.1 58.9 61.9 58.8 71.3 22.4 17.9 10.1 43.2 16.6 31.4 44.4 23.9 56.8 58.7 50.2 48.3 47.1 32.1 36.8 68.8 225.9 70.5 33.6 88.0 102.8 3.1 27.7 25.8 54.8 33.0 36.6 19.6 118.5 116.5 36.8 31.1 31.1 53.3 49.2 44.3 39.8 124.3 67.3 25.4 44.4 59.0 46.4 30.9 4.6 37.6 69.6 56.9 16.9 92.7 81.8 123.6 4.5 10.3 118.7 47.0 47.8 35.3 32.8 27.6 124.3 23.3 74.3 46.0 27.0 49.3 13.1 19.1 36.8 28.8 264.5 75.6 36.9 45.8 37.9 COMT ENSG00000093010 Catechol-O-methyltransferase P21964 22 19941371-19969975 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Catecholamine metabolism, Neurotransmitter degradation" "Methyltransferase, Transferase" "FDA approved drug targets, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 885.9;Syncytiotrophoblasts: 648.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 818.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001169, CAB011233" Enhanced Enhanced "Endoplasmic reticulum,Vesicles" NA NA 43000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "Endoplasmic reticulum" "CAB011233: , HPA001169: AB_1078402" "unprognostic (5.20e-2)" "unprognostic (2.73e-2)" "unprognostic (3.08e-2)" "prognostic favorable (3.68e-4)" "unprognostic (2.99e-2)" "unprognostic (2.32e-3)" "unprognostic (5.54e-3)" "unprognostic (9.14e-2)" "unprognostic (1.39e-1)" "unprognostic (1.40e-1)" "unprognostic (2.14e-3)" "prognostic favorable (5.67e-4)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.27e-1)" "unprognostic (7.09e-2)" "unprognostic (3.97e-1)" "unprognostic (1.07e-2)" 78.1 180.7 99.3 39.6 108.9 71.8 85.5 114.4 140.4 105.3 119.6 80.1 55.0 76.9 47.7 198.0 65.2 60.3 81.7 96.6 107.4 94.2 292.3 93.3 49.7 117.4 107.9 107.4 74.0 61.5 48.7 116.9 117.3 87.2 20.7 17.2 133.7 70.5 98.6 119.7 64.1 38.3 109.2 63.6 99.8 51.7 102.7 26.9 59.1 49.9 26.0 86.9 124.1 124.3 131.3 131.7 15.0 128.3 141.2 122.5 6.0 143.9 178.8 120.3 133.6 112.1 148.6 51.7 62.7 208.9 48.6 172.9 23.6 152.0 26.2 115.1 163.4 92.5 65.1 267.1 265.1 155.0 35.3 159.2 180.7 104.3 101.3 116.6 113.2 82.0 383.2 109.4 100.6 818.5 63.4 267.9 32.4 361.1 42.9 88.2 127.9 72.8 129.0 404.5 60.4 53.8 47.7 405.7 125.7 7.6 84.0 436.6 137.5 212.7 82.2 71.0 109.6 37.5 18.0 41.2 236.0 211.3 152.5 62.2 312.2 59.6 77.9 218.1 64.0 56.8 52.6 62.6 251.5 57.8 45.5 51.7 12.0 73.5 151.5 291.4 72.6 178.6 99.3 108.9 114.4 140.4 96.6 107.4 117.4 107.9 117.3 109.2 102.7 124.3 99.1 125.0 88.1 22.9 33.1 102.1 231.9 248.1 188.4 73.4 174.9 218.4 41.9 104.4 162.7 152.6 10.4 885.9 80.1 53.0 320.8 201.0 4.6 59.1 72.2 86.7 84.5 70.0 16.8 193.0 113.5 103.1 46.4 46.9 71.7 95.7 77.1 262.0 311.4 25.2 17.2 97.7 191.2 177.0 107.7 13.3 134.2 137.0 240.1 20.6 137.0 158.7 41.2 25.1 45.7 170.2 108.8 179.8 45.5 132.4 179.9 73.8 135.8 43.2 138.1 143.3 113.1 8.4 5.7 236.4 123.5 648.5 41.8 222.0 122.3 206.6 COPB1 COPB ENSG00000129083 "COPI coat complex subunit beta 1" P53618 11 14443440-14500027 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012338, HPA043954, HPA064403" Supported Enhanced "Golgi apparatus,Vesicles,Cytosol" NA NA 330000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles, Cytosol" "CAB012338: AB_726922, HPA043954: AB_2678746, HPA064403: AB_2685258" "unprognostic (2.35e-1)" "unprognostic (1.02e-3)" "unprognostic (1.36e-2)" "unprognostic (4.76e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (6.91e-4)" "prognostic unfavorable (5.63e-7)" "unprognostic (4.69e-3)" "unprognostic (3.42e-2)" "unprognostic (3.60e-1)" "prognostic unfavorable (8.04e-4)" "unprognostic (8.94e-2)" "unprognostic (1.78e-2)" "unprognostic (3.02e-2)" "unprognostic (8.00e-2)" "unprognostic (3.87e-1)" "unprognostic (1.69e-2)" 48.1 47.1 19.9 55.0 21.8 79.8 62.6 26.2 25.3 64.9 44.7 59.8 57.7 52.6 69.3 46.7 49.2 54.9 43.7 20.1 23.6 65.3 73.6 49.9 59.1 24.2 21.8 49.1 59.2 67.6 48.4 69.2 23.7 66.9 67.1 39.3 67.5 53.8 33.1 36.6 58.8 61.1 23.5 46.3 59.7 46.8 23.0 68.1 81.0 38.1 64.5 60.4 40.0 27.6 134.9 113.6 118.6 89.4 193.1 221.3 95.9 199.2 206.5 173.1 202.0 89.1 203.5 130.1 87.1 252.9 164.6 144.7 134.6 133.3 212.1 122.7 114.0 138.3 74.3 135.8 171.3 128.9 134.4 156.3 172.4 116.0 217.8 158.9 183.7 71.6 104.5 103.8 221.1 101.6 117.2 78.7 61.7 163.3 123.1 94.9 163.1 89.0 156.1 123.3 75.6 81.2 154.2 123.2 104.8 135.5 112.3 110.1 189.5 166.2 85.4 181.3 110.1 55.2 100.5 143.8 125.1 79.2 158.6 52.8 38.7 43.5 45.7 47.8 55.7 38.4 38.1 47.6 52.3 32.0 37.8 39.8 31.2 44.6 49.8 31.1 44.8 43.2 19.9 21.8 26.2 25.3 20.1 23.6 24.2 21.8 23.7 23.5 23.0 27.6 55.6 109.0 63.2 29.0 64.3 38.9 59.7 82.6 52.3 28.4 43.0 27.9 31.3 35.8 107.8 44.1 27.1 65.4 71.2 55.9 41.1 77.1 17.2 72.6 81.4 55.5 43.8 50.9 36.9 81.7 69.6 70.5 63.2 72.5 65.2 50.7 51.4 58.1 60.9 18.5 39.1 87.5 61.1 50.7 43.5 10.7 51.0 61.5 21.4 35.6 70.1 34.0 44.3 32.6 49.6 93.6 37.5 55.3 107.4 54.3 60.6 57.3 131.9 29.5 52.6 60.8 78.7 87.5 64.3 48.7 35.8 117.0 77.0 49.3 51.5 60.7 COPS2 "ALIEN, CSN2, TRIP15" ENSG00000166200 "COP9 signalosome subunit 2" P61201 15 49106068-49155661 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016867, HPA018271, HPA061071" Approved Supported "Vesicles,Cytokinetic bridge" Yes No 190000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" Vesicles "Cytokinetic bridge" "HPA016867: AB_1858336, HPA018271: AB_1858335, HPA061071: AB_2684424" "unprognostic (3.47e-1)" "unprognostic (2.28e-2)" "unprognostic (1.66e-1)" "unprognostic (7.20e-2)" "unprognostic (1.86e-1)" "unprognostic (7.84e-3)" "unprognostic (1.04e-1)" "unprognostic (6.77e-2)" "unprognostic (2.49e-2)" "unprognostic (6.09e-2)" "unprognostic (3.86e-3)" "unprognostic (1.42e-1)" "unprognostic (4.35e-3)" "unprognostic (1.02e-1)" "unprognostic (1.97e-1)" "unprognostic (5.62e-2)" "unprognostic (1.10e-3)" 61.7 43.4 24.8 34.4 28.5 124.5 67.0 35.0 36.8 61.9 25.3 43.2 43.3 58.4 44.0 63.2 43.2 53.7 61.5 26.1 30.4 60.8 57.6 35.0 45.5 30.9 27.7 76.7 54.0 65.7 26.4 45.0 32.8 45.2 41.6 32.2 40.0 47.0 92.6 35.5 37.2 56.5 35.2 32.0 36.4 51.0 27.5 49.6 61.8 112.1 48.8 59.0 35.3 41.7 92.0 53.1 111.6 94.4 134.2 189.9 76.7 157.3 149.8 135.4 123.5 113.0 49.1 151.1 105.2 152.2 108.7 131.9 160.3 130.9 148.0 103.3 64.5 141.0 105.4 91.7 102.6 134.7 70.7 161.2 104.3 110.4 193.3 149.3 144.0 82.5 184.4 78.8 149.3 49.5 72.3 67.3 72.6 128.4 68.9 78.2 105.2 227.7 143.5 136.5 108.4 78.6 90.7 96.4 127.8 129.4 95.6 133.3 93.4 132.1 71.0 249.6 167.9 71.0 196.3 191.0 123.4 215.1 109.4 11.7 17.9 12.2 13.1 23.5 24.4 14.6 19.7 19.2 21.0 13.9 24.8 16.2 7.4 16.6 22.9 13.3 28.4 16.0 24.8 28.5 35.0 36.8 26.1 30.4 30.9 27.7 32.8 35.2 27.5 41.7 72.8 76.9 56.1 14.4 50.0 87.1 57.1 90.8 80.8 23.2 47.6 59.3 104.3 27.1 69.8 23.9 10.4 56.1 48.2 18.5 54.8 40.3 28.2 56.7 91.6 53.6 20.8 50.1 35.2 29.9 71.0 79.6 36.2 94.0 52.6 39.3 46.1 32.5 43.9 33.7 36.1 25.1 32.6 47.5 44.9 21.6 55.3 46.1 35.6 19.7 49.3 24.8 27.8 21.6 48.7 35.9 21.6 53.4 63.5 53.0 41.0 84.8 47.4 19.7 19.7 74.6 109.0 93.1 43.3 63.2 98.9 131.9 54.0 58.6 34.6 64.4 CPE ENSG00000109472 "Carboxypeptidase E" P16870 4 165361194-165498547 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 643.3;retina: 741.7" "Cell type enhanced" "Detected in many" "Astrocytes: 727.4;Bipolar cells: 569.1;Cone photoreceptor cells: 621.3;Enteroendocrine cells: 587.4;Leydig cells: 500.8;Muller glia cells: 530.9;Peritubular cells: 621.0;Rod photoreceptor cells: 803.3;Sertoli cells: 854.6;Smooth muscle cells: 519.4" "Cancer enhanced" "Detected in all" "glioma: 240.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 311.6;SCLC-21H: 418.2;SiHa: 629.0;SuSa: 342.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003819, CAB024907" Supported Approved Nucleoplasm,Vesicles,Centrosome "Intracellular and membrane" NA NA 600000 "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 48: Smooth muscle cells - ECM organization" Centrosome "Nucleoplasm, Vesicles" "CAB024907: , HPA003819: AB_2667054" "unprognostic (1.84e-1)" "unprognostic (5.64e-3)" "unprognostic (1.61e-1)" "unprognostic (1.70e-2)" "unprognostic (2.51e-1)" "unprognostic (1.44e-2)" "unprognostic (1.65e-1)" "unprognostic (9.52e-2)" "unprognostic (2.91e-3)" "unprognostic (9.01e-2)" "unprognostic (4.84e-3)" "unprognostic (5.56e-3)" "prognostic unfavorable (2.60e-4)" "unprognostic (4.35e-3)" "unprognostic (1.46e-1)" "unprognostic (2.26e-1)" "prognostic unfavorable (2.12e-4)" 138.1 151.7 554.8 20.5 593.0 1.8 97.5 550.9 604.0 53.9 311.9 44.6 22.0 67.7 404.6 74.8 88.6 65.7 100.7 584.3 643.3 68.4 26.7 50.1 37.5 417.0 494.2 104.0 170.4 89.9 328.4 7.7 456.2 295.1 36.8 741.7 104.5 84.7 56.2 45.1 30.7 83.3 448.3 11.6 80.2 146.2 578.2 68.8 179.7 47.5 35.2 33.8 73.4 446.2 0.2 8.4 54.4 10.5 41.4 4.5 2.4 0.1 21.5 8.1 16.5 0.0 0.5 0.0 15.8 0.6 1.9 1.2 20.4 4.4 4.7 0.3 78.6 0.0 21.6 311.6 3.0 0.3 0.5 102.3 21.5 0.3 0.4 104.0 0.2 0.0 0.1 2.1 11.2 15.4 0.4 2.7 34.4 0.2 12.1 0.3 0.2 1.1 0.7 3.4 418.2 138.0 629.0 77.9 0.0 342.6 46.7 1.9 0.0 16.7 42.5 1.5 1.5 23.5 0.6 2.2 15.5 0.7 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 554.8 593.0 550.9 604.0 584.3 643.3 417.0 494.2 456.2 448.3 578.2 446.2 87.1 0.0 5.6 727.4 0.6 26.1 81.7 10.3 66.0 569.1 25.6 52.1 54.5 54.3 5.0 22.0 621.3 0.6 1.4 2.9 0.0 19.7 6.7 2.2 12.1 130.4 587.4 2.7 234.8 1.8 0.3 249.0 31.6 1.3 0.0 8.6 274.2 15.1 1.0 70.7 129.0 16.2 38.7 5.4 41.2 23.3 500.8 6.3 87.2 94.6 1.0 530.9 0.0 211.6 23.0 12.4 3.7 621.0 0.7 434.6 10.2 12.7 1.2 803.3 854.6 14.1 519.4 19.7 13.3 14.0 20.9 0.8 5.5 15.4 4.0 18.9 CPEB4 KIAA1673 ENSG00000113742 "Cytoplasmic polyadenylation element binding protein 4" Q17RY0 5 173888349-173961980 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 322.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "U-266/70: 112.1;U-266/84: 173.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038394 Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 16: U-266 - Nucleosome" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Golgi apparatus" Vesicles "HPA038394: AB_10671226" "unprognostic (2.12e-1)" "unprognostic (3.05e-1)" "unprognostic (1.12e-1)" "unprognostic (3.99e-1)" "unprognostic (8.80e-2)" "unprognostic (2.91e-1)" "unprognostic (4.58e-1)" "unprognostic (8.75e-2)" "unprognostic (2.54e-1)" "unprognostic (9.37e-3)" "unprognostic (1.44e-1)" "unprognostic (7.84e-2)" "prognostic favorable (4.99e-8)" "unprognostic (2.66e-1)" "unprognostic (4.73e-2)" "unprognostic (1.42e-2)" "unprognostic (3.83e-2)" 20.0 66.2 22.4 17.8 29.4 72.0 17.3 44.7 29.3 17.4 44.2 12.8 13.7 12.7 6.9 30.8 10.4 20.0 46.6 23.7 24.8 50.7 79.1 16.6 12.5 20.6 27.8 10.7 36.6 73.1 12.3 18.3 22.7 12.2 13.0 41.7 23.0 15.4 62.1 12.0 15.1 16.3 23.0 14.7 19.2 15.7 26.3 9.4 33.4 62.5 16.3 22.2 8.8 32.4 12.6 18.4 9.2 5.4 14.0 8.5 16.0 21.5 20.2 7.6 9.3 16.1 8.5 15.9 16.0 12.0 24.5 1.0 7.4 12.6 12.0 32.3 8.4 11.0 42.2 10.9 30.5 4.5 19.4 13.2 24.9 19.6 29.3 32.5 8.5 6.7 33.8 35.5 17.6 8.8 3.7 3.5 4.8 5.3 17.9 3.5 8.5 50.7 10.8 21.6 9.8 10.6 2.5 29.6 39.0 13.7 20.9 7.7 22.6 12.8 6.9 6.5 15.1 112.1 173.8 8.6 28.8 8.1 15.9 0.4 1.1 1.2 0.7 1.1 1.0 1.2 0.9 0.6 0.5 0.9 0.9 0.5 5.7 0.5 1.5 0.5 0.9 0.6 22.4 29.4 44.7 29.3 23.7 24.8 20.6 27.8 22.7 23.0 26.3 32.4 66.1 76.9 34.3 270.3 39.6 42.4 14.0 23.0 23.3 163.8 80.2 30.0 221.8 97.2 55.2 53.3 135.5 11.5 36.9 68.2 23.5 31.5 67.6 104.4 38.6 54.3 62.7 244.4 190.4 26.5 5.8 26.1 59.1 133.7 90.0 7.6 59.6 144.1 69.2 146.4 163.2 26.8 52.9 109.9 95.8 47.8 8.7 87.5 74.7 61.8 50.8 108.6 18.6 322.2 237.5 43.8 59.4 21.4 174.8 43.3 39.4 81.5 74.9 131.3 0.0 49.2 47.7 55.9 19.9 45.6 51.3 62.0 26.9 36.6 21.3 64.4 CPLX1 CPX-I ENSG00000168993 "Complexin 1" O14810 4 784957-826129 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Exocytosis, Neurotransmitter transport, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 273.5" "Cell type enhanced" "Detected in many" "Adipocytes: 45.5;Bipolar cells: 33.4;Endothelial cells: 29.6;Excitatory neurons: 44.2;Inhibitory neurons: 90.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 84.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071191, HPA074390" Supported Uncertain Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA071191: , HPA074390: " "unprognostic (9.21e-3)" "prognostic unfavorable (4.20e-4)" "unprognostic (3.45e-2)" "unprognostic (4.68e-2)" "unprognostic (1.16e-2)" "unprognostic (1.02e-1)" "unprognostic (3.14e-2)" "unprognostic (2.26e-2)" "unprognostic (9.52e-3)" "unprognostic (2.01e-2)" "prognostic favorable (5.05e-4)" "unprognostic (1.10e-3)" "unprognostic (3.32e-1)" "unprognostic (2.05e-2)" "unprognostic (1.12e-1)" "unprognostic (1.34e-1)" "unprognostic (7.77e-2)" 17.2 13.4 26.1 1.2 43.0 0.1 18.2 59.7 273.5 16.9 0.0 5.0 1.0 10.8 0.1 5.7 16.4 0.4 11.5 18.5 72.8 10.9 8.3 9.4 0.8 135.5 25.1 9.4 3.2 1.4 12.8 0.3 128.2 13.8 0.2 5.7 9.6 0.7 4.1 3.4 5.1 0.4 13.9 27.2 4.9 8.6 124.2 3.6 7.5 0.2 0.2 8.3 12.9 89.9 5.7 0.5 0.1 0.8 0.0 0.0 0.3 0.2 0.0 0.0 0.0 16.3 1.7 4.2 1.9 0.0 0.3 0.0 0.4 0.0 0.0 0.0 1.8 0.4 0.0 1.8 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 2.3 2.0 0.3 0.0 2.5 2.3 0.0 2.6 4.4 2.6 0.1 0.0 1.6 0.0 0.4 84.3 11.8 0.4 5.5 0.0 0.2 8.5 0.3 0.1 0.0 0.5 0.1 0.1 0.2 4.7 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 26.1 43.0 59.7 273.5 18.5 72.8 135.5 25.1 128.2 13.9 124.2 89.9 45.5 0.0 0.0 5.9 0.4 1.0 3.2 0.4 1.8 33.4 7.8 8.1 3.6 0.0 1.9 0.0 4.2 0.1 2.8 2.5 1.9 1.2 1.4 1.1 5.4 29.6 21.5 0.0 44.2 0.8 3.2 1.8 2.6 1.4 0.0 0.3 14.3 4.8 0.2 18.5 90.7 2.1 0.0 0.3 1.9 2.3 1.8 0.5 1.8 8.4 0.0 16.8 0.0 8.0 4.7 0.8 5.2 0.0 0.6 2.6 0.3 1.2 0.0 21.7 0.0 0.4 2.3 4.3 9.8 0.2 1.1 1.0 1.6 0.8 2.7 1.3 CPLX2 "CPX-2, DKFZp547D155" ENSG00000145920 "Complexin 2" Q6PUV4 5 175796310-175884021 "Predicted intracellular proteins" "Differentiation, Exocytosis, Mast cell degranulation, Neurogenesis, Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 308.9;epididymis: 128.6;pituitary gland: 65.6" "Group enriched" "Detected in some" 4 "Enteroendocrine cells: 36.6;Excitatory neurons: 44.7;Horizontal cells: 95.9;Inhibitory neurons: 35.9;Late spermatids: 32.9" "Cancer enhanced" "Detected in many" "liver cancer: 9.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 21 "A549: 496.4;Hep G2: 323.4;SCLC-21H: 201.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071191, HPA074390" Supported Uncertain Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 62: Horizontal cells - Visual perception" Vesicles "HPA071191: , HPA074390: " "unprognostic (1.36e-1)" "unprognostic (1.12e-1)" "unprognostic (2.81e-1)" "unprognostic (8.98e-2)" "unprognostic (1.23e-2)" "unprognostic (5.73e-2)" "unprognostic (5.16e-2)" "unprognostic (2.49e-3)" "unprognostic (6.22e-2)" "unprognostic (1.20e-2)" "unprognostic (2.06e-1)" "unprognostic (1.90e-5)" "unprognostic (6.88e-2)" "unprognostic (2.20e-1)" "unprognostic (7.32e-2)" "unprognostic (6.87e-2)" 0.7 28.3 239.7 1.0 136.0 0.0 0.1 78.2 291.5 0.0 0.0 3.5 2.1 0.0 128.6 0.1 0.0 0.0 0.2 308.9 62.3 0.1 0.2 1.3 0.0 62.2 98.8 0.2 9.0 0.1 65.6 0.0 50.2 0.2 1.4 19.4 0.1 0.0 0.2 0.1 1.6 0.3 0.0 0.0 5.0 3.0 19.6 0.1 0.2 0.0 0.0 0.1 0.5 157.7 0.0 496.4 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.3 323.4 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.1 0.3 2.1 15.2 0.1 0.0 0.0 0.6 0.0 0.2 201.3 16.3 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.3 0.1 0.0 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 239.7 136.0 78.2 291.5 308.9 62.3 62.2 98.8 50.2 0.0 19.6 157.7 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.2 36.6 0.0 44.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.9 35.9 1.0 0.0 0.0 0.0 32.9 0.9 0.0 0.0 4.7 0.0 1.1 0.0 5.5 3.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CPM ENSG00000135678 "Carboxypeptidase M" P14384 12 68842197-68971570 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 156.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 359.0;Alveolar cells type 2: 362.2;Kupffer cells: 368.5;Sertoli cells: 762.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 21.0;intermediate monocyte: 14.5;myeloid DC: 16.6;non-classical monocyte: 7.4" "Group enriched" "Detected in many" 5 "dendritic cells: 16.6;monocytes: 21.0" "Group enriched" "Detected in many" 4 "ASC diff: 71.1;ASC TERT1: 50.0;HSkMC: 91.2;SiHa: 68.9;THP-1: 26.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002657, HPA077243" Enhanced Uncertain Vesicles NA NA 7100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA002657: AB_1078398, HPA077243: " "unprognostic (1.74e-1)" "unprognostic (3.11e-1)" "unprognostic (2.88e-3)" "prognostic favorable (1.00e-4)" "unprognostic (4.58e-2)" "unprognostic (8.61e-2)" "unprognostic (1.57e-2)" "unprognostic (2.01e-1)" "unprognostic (8.42e-2)" "unprognostic (1.40e-1)" "unprognostic (1.35e-1)" "unprognostic (1.42e-1)" "unprognostic (1.47e-3)" "unprognostic (8.58e-2)" "unprognostic (6.85e-2)" "unprognostic (2.59e-2)" "unprognostic (1.06e-1)" 156.1 11.5 6.4 14.4 13.3 3.5 40.2 10.1 10.5 14.4 3.8 33.5 4.4 23.9 0.9 10.1 16.2 16.1 4.6 7.6 10.2 41.3 26.5 59.3 16.1 19.3 11.5 18.0 13.0 12.0 1.0 70.1 11.9 14.7 26.6 6.7 4.1 2.8 5.8 21.7 5.9 6.4 7.5 19.4 15.3 5.4 28.0 4.3 7.5 9.7 10.5 9.3 5.7 23.5 0.1 4.0 0.1 0.0 71.1 50.0 0.7 9.8 1.1 1.7 2.3 3.2 4.1 0.5 9.6 1.4 4.1 0.0 1.4 2.7 4.1 0.1 2.7 0.0 15.1 0.3 0.4 1.2 1.9 91.2 0.6 1.0 2.0 8.6 0.0 0.3 0.0 0.1 7.3 1.7 0.0 0.7 1.7 0.0 5.2 3.1 0.6 0.0 7.2 5.9 0.4 0.2 68.9 10.7 7.9 5.5 1.2 26.5 0.2 1.2 7.5 0.5 0.2 0.4 0.5 13.1 4.3 13.1 5.9 0.6 21.0 0.1 0.2 14.5 0.0 1.8 1.5 0.1 16.6 3.5 0.9 0.2 1.6 0.5 7.4 1.1 1.9 7.3 6.4 13.3 10.1 10.5 7.6 10.2 19.3 11.5 11.9 7.5 28.0 23.5 83.3 359.0 362.2 34.6 4.9 12.4 3.5 6.1 0.6 3.3 7.8 8.9 2.6 135.8 70.1 51.5 0.0 32.3 1.1 97.5 29.4 57.9 16.6 100.9 8.3 29.0 10.8 3.6 1.2 212.5 59.9 14.1 4.6 237.1 112.5 6.7 73.9 36.6 134.6 0.0 1.3 28.7 0.0 368.5 36.3 17.5 105.0 202.2 10.6 19.7 23.3 68.9 1.0 23.1 161.8 68.0 65.9 79.0 2.4 38.7 1.9 63.7 16.4 5.7 762.6 7.2 126.9 0.6 3.9 2.4 9.9 172.4 14.5 46.3 32.7 2.8 CPQ "LDP, PGCP" ENSG00000104324 "Carboxypeptidase Q" Q9Y646 8 96645242-97149654 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 225.9" "Cell type enhanced" "Detected in all" "Astrocytes: 150.2;Oligodendrocytes: 299.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 250.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 116.1;ASC TERT1: 131.4;hTERT-RPE1: 108.2;Karpas-707: 97.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023235, HPA024490" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 51000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "HPA023235: AB_1855257, HPA024490: AB_1855258" "unprognostic (4.04e-2)" "unprognostic (5.46e-2)" "unprognostic (4.45e-2)" "unprognostic (1.68e-1)" "unprognostic (1.51e-3)" "unprognostic (3.98e-3)" "unprognostic (5.24e-2)" "unprognostic (2.92e-2)" "unprognostic (2.67e-2)" "unprognostic (9.19e-2)" "unprognostic (2.38e-3)" "unprognostic (6.16e-3)" "prognostic favorable (5.40e-5)" "unprognostic (6.74e-3)" "unprognostic (8.71e-2)" "unprognostic (3.21e-2)" "unprognostic (1.75e-1)" 46.2 35.9 22.6 25.4 33.9 31.8 34.7 28.0 26.7 75.1 20.6 39.6 29.3 46.0 36.2 25.9 39.8 57.8 51.8 21.6 27.0 80.5 70.0 32.3 22.8 32.6 27.5 87.4 46.7 60.7 25.6 39.2 33.2 40.2 33.1 16.8 32.8 54.2 13.3 20.6 35.0 64.7 25.9 31.3 32.1 13.9 30.3 8.2 225.9 33.2 17.0 46.3 38.6 38.6 0.6 2.1 2.1 0.1 116.1 131.4 0.5 35.3 55.6 12.8 26.5 2.0 0.9 0.4 27.2 59.0 15.7 1.0 2.4 2.8 12.0 31.4 4.4 28.4 1.5 17.7 25.6 4.9 37.0 69.6 6.5 15.0 3.7 108.2 6.0 0.1 27.1 97.0 29.4 1.2 0.5 14.1 2.5 0.2 5.2 4.3 0.0 0.6 26.7 13.2 2.4 0.3 10.2 0.4 28.2 25.8 12.3 28.6 21.3 51.9 4.9 0.8 11.5 7.9 0.9 0.3 32.2 21.6 33.5 32.0 71.3 45.1 27.3 49.6 27.6 5.4 20.3 24.0 51.8 7.4 17.6 24.6 250.5 25.9 47.5 14.8 22.2 40.6 22.6 33.9 28.0 26.7 21.6 27.0 32.6 27.5 33.2 25.9 30.3 38.6 46.6 12.8 12.5 150.2 11.7 19.4 25.7 21.3 9.6 12.7 12.1 27.9 27.2 42.9 13.9 47.8 29.2 12.1 40.8 9.3 17.6 22.7 5.0 6.6 43.3 27.1 13.8 7.2 24.0 10.7 1.8 123.8 10.7 8.6 38.0 43.1 51.0 48.3 54.0 10.1 31.3 7.9 24.4 56.0 44.9 9.0 72.4 39.4 78.2 131.2 33.7 43.4 39.1 44.7 299.6 11.7 9.5 73.0 11.9 12.4 42.4 56.0 9.7 16.3 52.6 71.1 67.8 5.6 3.4 2.8 13.1 6.0 23.8 38.6 12.2 13.5 CPSF2 "CPSF100, KIAA1367" ENSG00000165934 "Cleavage and polyadenylation specific factor 2" Q9P2I0 14 92121969-92172145 "Plasma proteins, Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024238 Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Vesicles "HPA024238: AB_1847200" "unprognostic (2.31e-1)" "unprognostic (9.80e-2)" "unprognostic (3.73e-2)" "unprognostic (1.77e-2)" "unprognostic (4.95e-2)" "unprognostic (2.14e-2)" "prognostic unfavorable (4.35e-7)" "unprognostic (1.34e-1)" "unprognostic (2.94e-1)" "unprognostic (1.78e-2)" "unprognostic (2.33e-2)" "unprognostic (6.68e-2)" "unprognostic (8.78e-3)" "unprognostic (2.44e-1)" "unprognostic (2.91e-1)" "unprognostic (8.75e-2)" "unprognostic (4.90e-2)" 14.8 14.5 7.3 24.9 9.7 11.5 11.8 9.3 10.1 13.7 13.0 16.1 14.7 15.0 15.0 18.3 11.7 15.0 13.1 6.8 8.9 13.6 19.7 14.7 21.0 9.5 9.2 12.6 14.9 18.2 10.7 16.7 10.6 15.6 16.8 13.9 13.6 14.1 27.1 11.1 14.4 17.8 8.5 18.6 17.4 26.0 8.5 27.3 18.3 25.6 24.8 16.6 12.3 12.2 48.1 46.9 47.0 48.6 23.9 21.1 69.5 60.7 59.0 55.1 54.3 41.4 64.9 51.3 38.9 65.1 37.2 69.2 65.2 55.2 79.2 83.3 22.4 75.4 46.1 39.5 70.5 76.3 60.6 34.7 46.2 52.5 93.8 36.5 52.2 54.5 68.8 62.9 62.1 69.6 88.3 26.8 53.3 76.8 42.3 86.0 72.7 45.9 37.5 67.1 51.7 34.7 71.7 39.9 51.1 41.9 82.9 47.4 56.3 43.9 27.7 33.4 52.4 37.6 66.2 103.0 53.0 58.9 69.7 16.6 12.9 9.3 7.8 11.7 10.4 7.6 6.9 8.4 11.3 4.0 6.1 8.6 4.4 11.1 9.8 7.3 12.1 9.5 7.3 9.7 9.3 10.1 6.8 8.9 9.5 9.2 10.6 8.5 8.5 12.2 14.2 28.9 31.8 23.2 22.9 10.3 15.2 15.1 15.9 12.7 13.4 9.5 27.1 10.0 25.5 7.3 29.2 24.0 19.8 14.6 13.7 18.0 28.2 24.3 30.0 22.9 13.8 33.0 13.6 24.0 22.7 20.0 17.3 16.8 30.4 26.2 20.7 27.2 24.8 11.8 17.5 17.3 12.2 32.9 8.8 11.2 19.0 31.1 3.6 19.7 41.2 16.9 27.8 18.6 27.9 23.8 14.0 23.0 35.4 29.9 12.5 16.3 34.1 22.7 32.9 19.6 23.2 61.7 41.3 27.2 12.8 25.3 22.8 26.6 18.2 20.2 CPSF4 "CPSF30, NAR" ENSG00000160917 "Cleavage and polyadenylation specific factor 4" O95639 7 99438922-99457373 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 55.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049094, HPA066470" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 47: Cytotrophoblasts - Unknown function" Nucleoplasm Vesicles "HPA049094: AB_2680626, HPA066470: AB_2685672" "unprognostic (4.03e-3)" "unprognostic (1.36e-1)" "unprognostic (1.86e-1)" "unprognostic (1.90e-2)" "unprognostic (2.54e-2)" "unprognostic (1.44e-1)" "prognostic unfavorable (5.87e-4)" "unprognostic (5.84e-2)" "unprognostic (2.28e-2)" "unprognostic (3.15e-1)" "unprognostic (3.73e-3)" "unprognostic (3.36e-2)" "prognostic unfavorable (1.68e-4)" "unprognostic (2.47e-2)" "unprognostic (1.30e-1)" "unprognostic (1.37e-1)" "unprognostic (4.23e-2)" 20.4 19.0 31.4 13.8 30.8 20.1 19.2 29.9 35.1 18.7 23.6 16.7 14.0 16.8 11.7 20.4 15.7 11.3 17.4 30.1 30.4 17.3 20.2 15.4 23.7 35.5 31.6 18.8 29.9 8.3 18.4 16.7 32.1 19.1 10.7 7.2 19.8 12.3 36.1 20.4 16.1 11.1 30.4 22.0 20.0 32.0 32.3 16.1 13.9 18.0 19.9 16.0 17.4 30.4 40.0 33.9 55.4 44.9 22.4 25.5 66.8 25.8 31.5 38.8 50.5 56.0 52.0 56.4 34.2 25.2 48.2 34.0 39.1 40.5 35.4 41.9 41.6 27.0 41.4 54.4 117.2 49.4 33.3 46.8 34.0 40.7 60.4 28.1 35.8 40.1 70.8 64.8 36.2 95.6 99.6 88.9 51.3 53.0 47.7 40.8 37.0 66.8 24.2 36.1 43.3 50.6 29.4 60.9 61.6 58.2 25.3 51.8 20.0 36.5 50.1 64.3 50.0 59.9 68.6 83.3 28.1 48.1 44.1 1.2 3.4 2.6 3.3 3.0 4.4 8.2 5.0 6.1 4.1 8.4 6.3 5.6 1.3 4.4 2.1 5.4 8.2 3.0 31.4 30.8 29.9 35.1 30.1 30.4 35.5 31.6 32.1 30.4 32.3 30.4 11.6 6.4 8.9 6.2 11.2 8.8 16.4 10.6 9.6 4.6 11.9 10.3 10.4 14.3 8.6 1.8 10.4 55.9 17.7 8.7 15.6 15.6 3.0 4.9 9.3 11.0 7.7 15.6 10.7 17.1 33.1 12.7 5.1 5.3 12.7 27.0 8.2 8.2 21.5 6.7 14.7 10.6 14.2 10.1 13.5 7.8 27.4 8.7 8.8 5.6 18.5 10.7 14.4 6.0 8.1 13.9 6.0 17.3 14.7 28.6 10.1 20.2 4.3 6.9 19.7 23.7 16.4 20.9 19.8 9.3 9.2 45.4 10.7 25.1 12.6 14.9 CRB1 "LCA8, RP12" ENSG00000134376 "Crumbs cell polarity complex component 1" P82279 1 197268204-197478455 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 21.3;retina: 74.7" "Cell type enhanced" "Detected in some" "Astrocytes: 469.5;Cone photoreceptor cells: 164.7;Inhibitory neurons: 130.1;Muller glia cells: 79.7;Oligodendrocyte precursor cells: 280.0;Oligodendrocytes: 105.6;Rod photoreceptor cells: 149.3" "Cancer enriched" "Detected in single" 12 "glioma: 2.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "basophil: 7.7" "Lineage enriched" "Detected in single" 28 "granulocytes: 7.7" "Cell line enriched" "Detected in some" 8 "HeLa: 12.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA061250, HPA063127" Approved Uncertain Vesicles "Secreted in brain" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA061250: AB_2684458, HPA063127: AB_2684944" "unprognostic (1.96e-1)" "unprognostic (5.38e-3)" "unprognostic (2.92e-3)" "unprognostic (1.50e-2)" "unprognostic (5.13e-1)" "unprognostic (3.28e-2)" "unprognostic (2.38e-1)" "unprognostic (2.49e-2)" "unprognostic (1.05e-1)" "unprognostic (1.48e-3)" "unprognostic (2.59e-1)" "unprognostic (2.01e-3)" "unprognostic (1.78e-3)" "unprognostic (1.56e-1)" "unprognostic (3.36e-2)" "unprognostic (2.96e-1)" 0.1 0.1 15.7 0.0 17.6 0.4 0.1 19.8 20.5 0.0 9.6 0.1 0.0 0.0 0.1 0.1 0.4 0.0 0.2 15.8 14.2 0.1 0.0 0.1 0.1 18.7 18.4 0.7 0.4 0.0 2.2 0.0 17.5 0.0 0.0 74.7 0.0 0.0 0.7 0.0 0.0 0.0 18.9 0.0 0.2 2.9 16.1 0.0 0.2 0.5 0.0 0.0 0.0 21.3 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 12.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 15.7 17.6 19.8 20.5 15.8 14.2 18.7 18.4 17.5 18.9 16.1 21.3 0.0 0.0 0.0 469.5 0.0 0.3 0.2 0.3 0.0 15.0 0.2 0.1 1.1 0.0 0.2 0.0 164.7 0.0 0.0 0.0 0.0 0.0 1.9 0.2 0.0 0.7 0.0 11.6 53.2 0.0 0.0 0.2 0.0 0.0 0.0 6.4 0.0 0.0 0.0 1.7 130.1 0.0 2.0 0.0 0.5 1.6 1.8 0.0 0.0 24.4 0.0 79.7 0.0 280.0 105.6 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.9 149.3 0.0 0.2 0.1 1.8 0.3 0.0 0.3 0.0 0.1 0.2 0.0 0.0 CREB5 "CRE-BPA, H_GS165L15.1" ENSG00000146592 "CAMP responsive element binding protein 5" Q02930 7 28299321-28825894 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.0" "Cell type enhanced" "Detected in many" "Adipocytes: 165.7;Basal prostatic cells: 192.2;monocytes: 163.9;Oligodendrocyte precursor cells: 229.7;Oligodendrocytes: 734.9" "Cancer enhanced" "Detected in many" "renal cancer: 5.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 198.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 198.8" "Cell line enhanced" "Detected in many" "HL-60: 62.5;Karpas-707: 25.0;U-2 OS: 25.7;U-2197: 28.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA050020, HPA061622" Approved "Nucleoplasm,Vesicles,Plasma membrane" NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Vesicles, Plasma membrane" "HPA050020: AB_2680993, HPA061622: AB_2684569" "unprognostic (3.59e-2)" "unprognostic (3.80e-1)" "unprognostic (1.06e-1)" "unprognostic (6.46e-2)" "unprognostic (1.01e-1)" "unprognostic (4.90e-3)" "unprognostic (2.01e-3)" "unprognostic (2.87e-1)" "unprognostic (3.31e-1)" "unprognostic (1.04e-1)" "unprognostic (3.49e-1)" "unprognostic (2.67e-1)" "unprognostic (4.91e-3)" "unprognostic (6.61e-2)" "unprognostic (3.95e-1)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" 10.5 1.3 6.3 7.9 20.5 6.1 5.0 6.8 12.7 1.7 0.0 3.5 0.9 8.4 2.8 3.5 2.2 11.4 5.3 9.6 19.9 3.0 1.8 6.1 0.9 19.7 14.6 0.7 3.2 0.2 1.1 3.7 15.8 1.2 1.7 1.3 3.5 1.0 3.2 2.9 2.2 4.7 2.9 7.4 1.4 0.7 23.0 0.7 1.8 4.0 0.8 4.4 2.2 35.0 0.1 0.6 7.3 0.4 0.4 10.3 0.3 0.7 1.6 4.4 6.6 4.2 2.7 18.9 1.3 1.8 4.5 0.7 0.2 6.4 13.8 0.0 5.0 20.4 4.2 0.4 0.4 62.5 0.7 1.3 1.2 18.9 20.1 0.9 3.0 0.1 2.4 25.0 1.5 0.1 0.1 0.0 9.1 0.1 7.4 0.5 6.8 0.5 9.0 2.0 0.7 5.2 0.3 0.4 2.2 10.0 0.2 1.5 0.8 8.6 25.7 28.7 8.5 1.5 4.5 0.2 9.4 0.3 14.8 0.1 29.9 0.0 0.0 9.7 0.0 1.9 0.0 0.0 18.2 0.1 0.0 0.0 198.8 0.0 3.9 0.3 0.0 7.0 6.3 20.5 6.8 12.7 9.6 19.9 19.7 14.6 15.8 2.9 23.0 35.0 165.7 6.4 7.2 10.7 3.2 21.9 192.2 8.2 13.1 1.3 10.7 8.9 16.8 17.2 6.3 12.9 0.0 4.0 0.8 0.0 1.9 74.2 0.4 41.0 56.3 31.3 0.0 0.4 17.0 27.4 13.4 108.0 3.1 69.7 14.0 0.6 14.3 0.5 8.3 5.0 22.2 0.0 6.1 47.4 118.2 1.6 5.9 75.8 30.2 22.5 163.9 14.3 4.1 229.7 734.9 22.5 0.0 0.4 3.2 44.9 0.0 25.6 4.7 0.9 19.7 143.5 31.8 12.6 7.3 12.0 13.2 24.8 3.1 2.6 0.0 35.1 CREG1 CREG ENSG00000143162 "Cellular repressor of E1A stimulated genes 1" O75629 1 167529117-167553805 "Predicted secreted proteins" "Growth regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 545.7;Kupffer cells: 559.7;monocytes: 322.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 55.4;classical monocyte: 128.4;eosinophil: 75.7;intermediate monocyte: 75.7;myeloid DC: 89.9;neutrophil: 43.7;non-classical monocyte: 72.3" "Group enriched" "Detected in all" 6 "dendritic cells: 89.9;granulocytes: 75.7;monocytes: 128.4" "Cell line enhanced" "Detected in all" "RPMI-8226: 1237.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056390 Approved Vesicles,Microtubules "Secreted to blood" NA NA 520000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Microtubules Vesicles "HPA056390: AB_2683113" "unprognostic (3.25e-1)" "unprognostic (2.00e-1)" "unprognostic (1.91e-1)" "unprognostic (9.65e-3)" "unprognostic (4.64e-2)" "unprognostic (2.35e-2)" "unprognostic (1.55e-1)" "unprognostic (5.02e-2)" "unprognostic (2.07e-3)" "unprognostic (8.54e-2)" "unprognostic (8.65e-2)" "unprognostic (1.21e-1)" "unprognostic (8.24e-3)" "unprognostic (2.99e-1)" "unprognostic (4.63e-2)" "unprognostic (3.78e-3)" "unprognostic (3.16e-1)" 130.5 127.7 37.5 79.0 41.1 125.9 109.7 39.0 45.9 76.8 47.8 77.1 60.3 61.8 109.7 91.7 70.9 128.2 82.2 36.5 40.4 132.1 295.2 99.1 98.9 46.0 39.1 84.2 70.7 75.4 64.8 110.8 44.4 62.9 82.7 80.0 104.5 74.6 71.4 109.8 63.0 77.9 45.7 136.9 61.4 50.1 49.3 35.5 125.8 78.2 63.5 116.3 63.3 61.2 93.5 41.5 21.1 43.5 325.8 89.8 53.0 39.2 17.8 30.7 39.8 67.8 104.4 101.7 112.2 43.6 57.2 143.3 24.3 84.9 20.9 140.3 82.3 41.5 31.1 37.9 111.5 93.6 295.2 94.5 250.5 35.6 38.7 42.7 10.3 35.9 218.5 405.0 42.6 39.2 19.6 95.9 22.8 214.0 63.9 32.5 58.8 1237.2 54.7 64.9 14.0 25.7 98.1 132.8 112.8 70.1 175.5 252.7 19.1 8.0 39.6 126.2 25.9 79.4 168.4 67.7 131.6 96.0 16.3 55.4 128.4 75.7 5.1 75.7 8.0 4.3 7.5 6.5 89.9 2.1 16.6 8.8 43.7 11.0 72.3 6.2 3.9 57.6 37.5 41.1 39.0 45.9 36.5 40.4 46.0 39.1 44.4 45.7 49.3 61.2 44.7 35.3 90.1 5.9 15.3 44.1 49.1 23.1 56.9 17.9 61.7 63.8 55.7 65.8 32.2 55.2 89.6 91.5 18.3 15.6 23.5 36.0 27.6 33.9 19.3 34.2 29.3 124.8 24.7 39.7 41.7 78.4 21.9 64.1 29.9 62.0 48.2 90.3 545.7 15.2 22.1 44.5 14.2 559.7 57.6 27.4 43.5 213.8 24.9 26.2 322.8 30.5 6.2 10.1 14.6 21.0 31.5 28.6 27.8 34.0 46.3 60.6 18.5 31.5 13.1 43.2 40.8 65.5 42.0 86.3 51.1 126.7 17.3 38.9 50.4 44.0 CREM hCREM-2 ENSG00000095794 "CAMP responsive element modulator" Q03060 10 35126791-35212958 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 216.6" "Cell type enhanced" "Detected in all" "dendritic cells: 819.1;Early spermatids: 2013.6;Langerhans cells: 1094.0;Late spermatids: 814.3;T-cells: 612.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 103.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001818, CAB018352" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 13: T-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Vesicles "CAB018352: AB_673599, HPA001818: AB_1078566" "unprognostic (1.78e-1)" "unprognostic (6.26e-3)" "unprognostic (7.09e-2)" "unprognostic (2.51e-2)" "unprognostic (6.22e-3)" "unprognostic (9.27e-3)" "unprognostic (1.16e-1)" "unprognostic (2.41e-2)" "unprognostic (1.32e-1)" "unprognostic (7.66e-3)" "unprognostic (8.98e-2)" "unprognostic (3.42e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (4.44e-2)" "unprognostic (4.19e-1)" "unprognostic (1.66e-2)" "unprognostic (1.52e-1)" 54.9 137.4 31.9 51.0 34.3 22.0 27.1 31.3 39.2 26.4 38.6 24.5 8.9 30.3 11.4 17.6 29.2 44.5 50.5 33.6 42.9 58.8 60.5 30.5 17.6 36.7 35.5 60.6 16.0 24.5 59.5 100.3 36.0 32.0 13.6 23.5 13.4 23.3 30.0 9.0 15.9 24.5 34.1 25.3 20.7 216.6 35.8 29.3 22.3 31.3 16.9 60.5 19.1 33.5 24.8 39.0 32.3 33.2 22.2 23.0 32.2 31.8 24.8 19.6 27.0 4.6 10.2 42.0 30.2 18.7 21.2 5.6 28.0 20.8 28.5 103.8 20.6 14.9 25.7 18.6 26.5 3.6 15.2 20.4 25.9 38.3 11.7 17.2 55.3 31.1 44.3 16.9 30.4 20.0 26.1 10.8 9.6 9.2 88.6 16.0 16.9 7.8 34.8 9.7 7.5 20.4 15.1 13.1 88.7 36.5 7.2 11.0 74.0 14.9 19.1 41.4 21.3 7.4 10.9 14.6 35.6 33.1 13.0 5.3 3.5 11.5 11.5 5.5 14.6 7.0 12.6 10.4 4.1 6.8 9.0 10.4 9.7 10.2 4.2 12.4 16.2 8.5 31.9 34.3 31.3 39.2 33.6 42.9 36.7 35.5 36.0 34.1 35.8 33.5 98.7 19.2 47.9 42.7 301.8 143.4 58.0 30.9 18.8 18.3 32.1 32.4 62.3 20.0 33.2 165.5 6.2 98.7 819.1 16.8 97.8 40.6 2013.6 32.6 27.6 118.7 69.0 5.7 50.1 44.4 109.1 140.6 29.0 44.2 347.7 14.5 17.9 37.6 120.6 10.1 34.3 17.9 32.6 61.4 1094.0 814.3 26.1 286.1 247.3 30.0 187.4 39.0 65.9 113.1 34.9 30.6 19.7 32.7 109.4 49.5 15.3 64.2 46.1 19.5 46.0 45.5 232.8 464.7 156.8 15.9 108.4 230.0 612.4 46.4 13.6 52.7 CROT COT ENSG00000005469 "Carnitine O-octanoyltransferase" Q9UKG9 7 87345664-87399794 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 136.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 71.7;RT4: 72.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019052, HPA019364, HPA019365" Enhanced Approved Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "HPA019052: AB_1847172, HPA019364: AB_1847173, HPA019365: AB_1847174" "unprognostic (2.80e-2)" "unprognostic (6.47e-2)" "unprognostic (1.75e-1)" "unprognostic (4.56e-2)" "unprognostic (1.70e-1)" "unprognostic (2.55e-2)" "unprognostic (1.84e-1)" "unprognostic (9.93e-3)" "unprognostic (2.13e-1)" "unprognostic (1.13e-1)" "unprognostic (9.84e-2)" "unprognostic (3.48e-1)" "prognostic favorable (2.55e-6)" "unprognostic (3.52e-2)" "unprognostic (1.34e-1)" "unprognostic (7.60e-3)" "prognostic favorable (4.02e-4)" 5.4 10.5 4.8 6.3 6.1 3.2 16.1 5.9 6.1 11.8 7.9 12.6 31.9 7.8 18.5 19.3 10.7 14.1 6.6 5.7 5.1 16.9 35.0 6.6 6.2 4.6 5.0 8.6 6.7 18.7 6.0 19.0 4.5 21.1 11.0 35.4 9.3 27.5 11.3 24.6 23.6 8.6 4.9 5.4 6.8 3.3 5.3 7.6 40.5 9.5 8.5 25.2 19.0 5.6 15.3 10.9 13.5 4.7 12.6 11.5 9.9 15.7 14.8 9.4 10.1 6.0 7.9 6.4 13.6 13.6 18.9 18.9 2.3 21.2 13.5 9.1 9.5 13.9 7.8 7.6 8.1 8.8 8.3 9.4 71.7 7.6 6.0 12.1 13.7 10.4 0.7 9.0 25.2 15.0 11.2 8.8 3.0 5.5 16.4 5.0 18.6 1.1 12.3 72.1 2.2 10.5 19.2 22.3 10.6 9.2 14.2 3.1 7.2 22.0 9.5 29.8 15.2 13.6 21.0 8.8 14.8 0.1 13.3 2.0 1.3 3.4 6.6 1.7 8.7 2.0 6.7 5.5 1.9 1.9 5.3 5.9 0.8 13.0 6.2 2.2 6.2 2.8 4.8 6.1 5.9 6.1 5.7 5.1 4.6 5.0 4.5 4.9 5.3 5.6 8.6 22.4 10.0 18.9 5.1 16.8 56.4 45.0 65.4 16.9 17.5 12.7 14.9 14.3 35.0 53.3 45.9 136.5 9.0 21.0 9.8 7.6 28.7 9.5 9.3 7.2 7.3 4.8 26.3 8.7 7.9 12.0 11.2 12.1 7.6 9.5 5.3 29.7 13.6 15.2 11.1 15.8 16.2 6.3 4.8 63.1 15.8 5.9 19.6 7.5 6.3 25.9 22.6 15.6 16.1 11.1 9.9 13.9 4.8 20.1 53.7 19.9 24.1 79.7 6.6 10.0 10.1 2.4 4.8 29.6 15.3 49.0 9.6 8.7 15.1 48.4 CRP PTX1 ENSG00000132693 "C-reactive protein" P02741 1 159712289-159714589 "Cancer-related genes, Candidate cardiovascular disease genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 79 "liver: 9388.5" "Group enriched" "Detected in some" 16 "Ductal cells: 1087.7;Hepatocytes: 4142.7" "Cancer enriched" "Detected in some" 13 "liver cancer: 1010.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.3;HDLM-2: 6.3;U-2 OS: 4.5;U-266/84: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB005036, HPA027367, HPA027396" Supported Approved "Nucleoplasm,Vesicles,Intermediate filaments" "Secreted to blood" NA NA 2920000000 5200000000 "Cluster 62: Liver - Hemostasis" "Cluster 16: U-266 - Nucleosome" "Cluster 15: Hepatocytes - Hemostasis" "Nucleoplasm, Vesicles" "Intermediate filaments" "CAB005036: AB_562362, HPA027367: AB_1847216, HPA027396: AB_1847217" "unprognostic (3.74e-1)" "unprognostic (5.31e-2)" "unprognostic (2.97e-2)" "unprognostic (1.27e-1)" "unprognostic (3.57e-2)" "unprognostic (1.33e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (4.17e-10)" "unprognostic (3.39e-2)" "unprognostic (3.48e-1)" "unprognostic (5.60e-2)" "unprognostic (6.61e-2)" 3.4 0.7 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.8 0.0 0.3 0.0 3.1 0.0 0.5 0.4 111.7 0.7 0.0 0.0 0.7 9388.5 0.5 0.1 0.0 0.0 0.4 118.5 0.0 0.3 0.1 0.0 0.6 0.0 0.0 0.4 0.0 0.3 0.6 0.5 0.0 0.0 6.1 0.4 0.4 0.0 0.0 0.3 0.0 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.2 0.0 0.0 0.0 6.3 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.1 0.8 0.0 11.7 1.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 118.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1087.7 1.4 0.0 0.1 6.3 0.0 163.2 0.0 63.2 0.0 0.0 0.0 0.2 0.0 0.0 89.6 4142.7 0.1 0.0 0.0 0.0 0.0 98.8 0.3 0.7 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 60.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 CRYGA "CRY-g-A, CRYG1, CRYG5" ENSG00000168582 "Crystallin gamma A" P11844 2 208160740-208163589 "Predicted intracellular proteins" "Eye lens protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Oligodendrocyte precursor cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA043386 Supported Uncertain Vesicles,Cytosol NA NA "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" "HPA043386: " "unprognostic (1.49e-1)" 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.2 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.2 0.7 0.6 0.3 0.2 0.3 0.2 0.3 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CRYGB CRYG2 ENSG00000182187 "Crystallin gamma B" P07316 2 208142573-208146158 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 5 "Early spermatids: 1.1" "Group enriched" "Detected in some" 6 "ovarian cancer: 1.1;testis cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "hippocampal formation: 3.3;hypothalamus: 2.2;thalamus: 2.0" HPA043386 Supported Approved Vesicles,Cytosol NA NA "Cluster 29: Early spermatids - Spermatogenesis" "Vesicles, Cytosol" "HPA043386: " "unprognostic (6.73e-2)" "unprognostic (1.31e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CRYGC CRYG3 ENSG00000163254 "Crystallin gamma C" P07315 2 208128137-208129828 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "testis: 1.7" "Group enriched" "Detected in some" 13 "Early spermatids: 1.9;Granulosa cells: 3.7;Late spermatids: 3.2;Spermatocytes: 2.1;Spermatogonia: 2.4" "Cancer enhanced" "Detected in some" "endometrial cancer: 0.8;ovarian cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "hippocampal formation: 3.2;hypothalamus: 1.5;thalamus: 1.2" "Group enriched" "Detected in some" 14 "cerebral cortex: 1.2;hippocampal formation: 1.5" HPA043386 Supported Approved Vesicles,Cytosol NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Cytosol" "HPA043386: " "unprognostic (1.89e-1)" "unprognostic (2.89e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CRYGD CRYG4 ENSG00000118231 "Crystallin gamma D" P07320 2 208121607-208124524 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "ovary: 8.0" "Cell type enriched" "Detected in some" 4 "Granulosa cells: 140.2" "Cancer enhanced" "Detected in some" "testis cancer: 3.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 20 "HEL: 10.0" "Not detected" "Not detected" "HPA041269, HPA043386" Supported Approved Vesicles,Cytosol NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Cytosol" "HPA041269: AB_2732491, HPA043386: " "unprognostic (4.49e-2)" "unprognostic (2.64e-1)" "unprognostic (3.62e-1)" 0.0 0.0 0.5 0.0 0.4 1.3 0.0 0.2 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.5 0.6 0.0 0.0 0.0 0.0 0.5 0.7 8.0 0.0 0.0 0.4 0.0 0.6 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.2 0.8 0.5 0.6 0.5 0.7 0.6 0.3 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.1 0.0 4.6 0.3 0.0 0.1 0.9 0.0 0.0 0.0 140.2 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 4.2 0.0 0.4 0.0 0.0 0.0 34.5 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.9 0.1 1.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 CSF1R "C-FMS, CD115, CSFR, FMS" ENSG00000182578 "Colony stimulating factor 1 receptor" P07333 5 150053291-150113372 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 113.3;placenta: 103.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 103.2;Hofbauer cells: 340.4;Kupffer cells: 291.2;Langerhans cells: 73.4;Macrophages: 196.3;Microglial cells: 134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 444.6;non-classical monocyte: 646.9" "Lineage enriched" "Detected in many" 5 "monocytes: 646.9" "Group enriched" "Detected in some" 4 "BEWO: 123.0;SK-BR-3: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008970, HPA012323" Uncertain Supported "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 1600000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Plasma membrane" "CAB008970: , HPA012323: AB_1848977" "unprognostic (3.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-3)" "unprognostic (9.83e-2)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (3.67e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (1.72e-2)" "unprognostic (4.61e-2)" 51.3 31.0 19.6 75.1 17.1 5.6 19.3 20.2 21.4 21.6 19.3 21.9 24.3 12.1 5.8 21.0 17.2 40.6 16.6 19.8 33.8 7.1 27.5 36.6 54.4 41.4 35.5 12.7 9.9 11.8 5.7 103.3 40.1 9.1 21.5 1.5 10.1 20.8 3.2 13.4 37.3 41.9 36.6 113.3 21.0 7.0 40.6 14.3 6.0 11.8 21.7 42.6 3.8 67.6 4.5 0.2 0.0 0.0 1.9 0.4 123.0 0.2 0.2 0.0 0.0 3.8 0.0 5.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.2 1.1 3.0 0.0 6.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 6.1 0.1 0.0 0.0 0.0 1.9 0.6 0.0 0.0 0.2 0.2 0.0 47.8 0.0 1.9 0.0 20.7 0.0 0.8 0.2 0.1 3.3 0.0 0.3 0.1 6.6 2.6 0.0 3.0 138.4 4.0 0.6 444.6 0.6 0.3 0.2 0.4 139.0 0.2 0.3 0.2 21.6 0.2 646.9 11.1 0.5 132.7 19.6 17.1 20.2 21.4 19.8 33.8 41.4 35.5 40.1 36.6 40.6 67.6 2.0 0.0 3.8 0.0 4.3 2.8 0.0 0.0 1.2 0.0 0.5 2.3 3.1 4.3 0.0 0.0 0.0 6.2 2.8 0.0 0.0 0.0 4.8 0.0 0.1 10.5 0.0 2.5 0.4 0.0 103.2 2.2 1.5 0.2 2.5 8.3 2.9 1.5 340.4 0.0 0.5 0.3 0.0 291.2 73.4 5.4 1.8 196.3 3.6 134.9 39.4 0.0 1.0 1.5 0.3 0.1 1.7 0.0 1.0 0.0 0.0 0.1 0.7 0.5 13.1 1.2 2.0 2.2 0.2 0.4 1.3 26.4 1.3 2.2 0.2 0.0 CSF2 "GM-CSF, GMCSF" ENSG00000164400 "Colony stimulating factor 2" P04141 5 132073789-132076170 "Cancer-related genes, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lung: 2.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 11.4;Basal respiratory cells: 11.3;dendritic cells: 17.7;Ductal cells: 18.3;Pancreatic endocrine cells: 24.9;T-cells: 28.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "NK-cell: 6.2" "Lineage enriched" "Detected in single" 12 "NK-cells: 6.2" "Cell line enriched" "Detected in some" 4 "BJ hTERT+: 91.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA057404, HPA062006" Enhanced Vesicles "Secreted to blood" NA NA 23900 "Cluster 15: NK-cells - Transcription" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Vesicles "HPA057404: AB_2683428, HPA062006: AB_2684654" "unprognostic (7.29e-2)" "unprognostic (2.49e-3)" "unprognostic (8.77e-2)" "unprognostic (2.09e-2)" "unprognostic (1.05e-2)" "unprognostic (1.26e-1)" "unprognostic (2.56e-1)" "unprognostic (1.47e-2)" "unprognostic (2.64e-1)" "unprognostic (3.68e-3)" "unprognostic (1.87e-8)" "unprognostic (4.81e-2)" "unprognostic (1.22e-1)" "unprognostic (9.07e-2)" "unprognostic (2.06e-2)" 0.0 0.0 0.1 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.0 2.0 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 9.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 91.3 0.1 5.1 0.0 7.4 0.0 1.5 0.0 5.3 0.2 0.0 6.8 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 20.8 13.8 2.5 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.4 1.3 0.0 0.0 0.0 3.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.3 3.8 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 3.2 11.4 0.0 0.3 1.5 0.1 11.3 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.0 0.0 17.7 0.1 0.0 18.3 0.0 0.3 0.2 4.8 0.0 0.0 0.0 1.1 0.0 0.4 0.0 0.2 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 24.9 0.0 0.0 0.7 1.0 0.0 0.0 0.6 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.6 0.0 28.6 0.0 0.0 1.1 CSK ENSG00000103653 "C-terminal Src kinase" P41240 15 74782057-74803198 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 169.3" "Cell type enhanced" "Detected in all" "B-cells: 130.9;dendritic cells: 99.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011203, HPA026488, HPA028425" Approved Approved Enhanced Vesicles,Cytosol No No 150000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Vesicles, Cytosol" "CAB011203: AB_259070, HPA026488: AB_1847273, HPA028425: AB_10600899" "unprognostic (1.05e-1)" "prognostic favorable (5.14e-5)" "unprognostic (2.59e-3)" "prognostic favorable (8.22e-4)" "unprognostic (4.15e-2)" "unprognostic (4.11e-2)" "unprognostic (1.87e-1)" "unprognostic (2.96e-1)" "unprognostic (2.20e-1)" "unprognostic (1.31e-1)" "unprognostic (4.12e-2)" "unprognostic (4.61e-2)" "prognostic unfavorable (1.74e-4)" "prognostic favorable (1.07e-4)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "unprognostic (6.29e-2)" 21.4 19.9 23.4 89.1 26.2 50.6 19.4 26.5 26.7 26.8 18.2 33.6 36.7 22.4 8.0 98.5 20.0 22.9 29.3 22.5 23.9 21.3 48.8 32.0 169.3 31.0 29.8 19.0 17.2 15.8 21.1 17.6 31.6 24.8 19.5 6.9 31.6 14.1 14.8 36.7 59.9 18.7 29.1 127.9 30.0 19.2 28.2 68.5 19.5 15.8 106.3 33.0 32.8 28.4 62.2 85.6 41.2 68.1 38.5 29.2 35.3 40.7 38.8 75.7 53.6 78.9 56.0 275.7 52.6 37.0 70.2 62.9 87.2 82.1 21.2 134.7 107.8 233.8 29.5 80.2 53.3 123.6 285.1 41.7 39.6 54.0 48.1 37.9 58.1 127.5 68.7 93.1 45.7 104.6 89.7 72.7 51.2 55.7 60.6 98.0 35.4 201.9 34.9 135.6 68.1 47.2 52.8 109.5 72.3 26.2 75.5 179.5 50.7 91.1 47.8 72.5 71.7 49.6 108.7 283.8 47.1 232.5 63.1 88.7 68.0 176.1 74.3 146.8 63.4 95.6 63.6 73.9 76.6 113.6 48.3 57.0 130.8 58.6 169.8 44.3 106.2 79.5 23.4 26.2 26.5 26.7 22.5 23.9 31.0 29.8 31.6 29.1 28.2 28.4 21.3 3.2 9.2 8.5 130.9 9.3 8.2 7.6 13.1 16.6 16.7 17.1 11.5 12.8 9.3 9.2 6.2 7.5 99.1 40.6 1.9 9.3 15.8 10.0 15.1 15.3 9.5 29.2 5.3 14.0 13.7 11.3 27.0 15.3 26.6 19.0 12.5 34.3 50.7 28.6 10.0 23.2 6.1 91.2 44.9 3.3 9.0 85.1 8.8 23.4 86.9 6.4 90.6 3.5 4.7 21.2 18.4 8.2 56.7 13.9 27.5 8.0 9.3 5.1 6.6 6.9 18.1 5.7 12.5 49.4 9.1 5.6 90.3 21.5 27.5 14.9 CSMD1 "KIAA1890, PPP1R24" ENSG00000183117 "CUB and Sushi multiple domains 1" Q96PZ7 8 2935353-4994972 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 10.7" "Group enriched" "Detected in some" 20 "Excitatory neurons: 4868.4;Inhibitory neurons: 3913.1;Oligodendrocyte precursor cells: 4521.8" "Cancer enhanced" "Detected in some" "testis cancer: 0.9" "Region enhanced" "Detected in many" "cerebral cortex: 10.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 4.9;U-2 OS: 2.2;U-266/70: 2.2;U-266/84: 2.1;U-698: 1.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA074707 Approved Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA074707: AB_2686707" "unprognostic (6.32e-2)" "unprognostic (4.23e-2)" "unprognostic (2.37e-1)" "unprognostic (1.67e-3)" "unprognostic (5.72e-2)" "unprognostic (4.26e-2)" "unprognostic (1.02e-2)" "unprognostic (4.66e-2)" "unprognostic (7.69e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-1)" "unprognostic (7.90e-2)" "unprognostic (1.01e-1)" "unprognostic (2.74e-2)" "unprognostic (5.09e-2)" "unprognostic (1.26e-2)" "unprognostic (1.11e-1)" 0.1 0.0 3.5 0.0 5.8 0.0 0.2 0.0 10.7 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 5.8 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.1 0.0 1.6 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.6 0.0 2.5 0.0 0.0 0.1 0.2 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.2 0.0 0.0 2.2 2.1 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 5.8 0.0 10.7 5.8 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.6 0.0 0.5 108.4 0.0 0.3 0.0 0.0 2.2 15.0 1.0 0.9 2.2 0.0 0.6 1.8 0.0 3.4 0.0 0.1 0.0 0.0 52.5 1.5 0.3 2.2 0.0 0.0 4868.4 0.0 1.3 0.7 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 3913.1 0.1 0.0 0.0 0.7 15.0 0.3 0.2 0.0 220.2 0.7 0.5 0.0 4521.8 135.2 0.0 0.1 0.4 0.0 0.0 0.0 1.2 9.7 0.6 0.0 0.2 0.5 10.2 5.3 1.0 0.1 3.6 0.1 2.8 0.0 0.1 CSNK1G2 CK1g2 ENSG00000133275 "Casein kinase 1 gamma 2" P78368 19 1941172-1981338 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 254.8;Late spermatids: 613.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034868, HPA056572" Uncertain Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA034868: AB_10671235, HPA056572: AB_2683178" "unprognostic (2.00e-1)" "unprognostic (2.15e-1)" "unprognostic (1.83e-1)" "unprognostic (2.42e-3)" "unprognostic (6.51e-3)" "unprognostic (2.27e-3)" "unprognostic (1.14e-3)" "unprognostic (2.00e-1)" "unprognostic (9.42e-2)" "unprognostic (5.78e-2)" "unprognostic (4.83e-3)" "unprognostic (4.09e-3)" "unprognostic (7.95e-2)" "unprognostic (4.65e-3)" "unprognostic (5.09e-1)" "unprognostic (2.01e-1)" "unprognostic (1.63e-2)" 37.1 52.7 19.3 40.5 17.9 47.3 38.3 22.8 28.1 35.1 18.3 35.0 29.5 34.5 6.5 50.6 35.7 20.6 33.8 21.6 16.6 42.6 41.6 53.5 41.8 20.8 19.2 39.5 39.8 13.3 51.5 17.7 18.1 41.3 8.7 9.8 38.1 14.0 39.4 45.1 46.9 10.3 12.8 69.2 35.5 99.9 18.3 23.5 35.8 12.3 18.7 32.3 37.8 18.1 71.2 37.3 51.0 80.1 17.5 32.6 42.7 43.1 28.0 32.0 39.1 31.0 37.8 44.3 35.2 27.6 17.8 50.1 27.6 52.5 14.0 40.5 60.4 31.2 65.0 52.9 28.2 50.7 76.3 32.5 33.8 33.4 21.3 24.7 38.4 54.2 67.1 146.5 21.4 41.3 101.0 66.8 92.7 19.7 41.8 86.8 32.3 72.7 24.3 73.2 81.9 67.4 32.2 52.7 48.2 18.8 33.6 81.8 46.6 40.2 31.5 85.3 50.6 94.8 54.5 55.5 40.7 47.6 42.8 2.8 3.6 4.7 4.2 5.8 3.0 3.4 3.1 3.6 3.6 3.3 2.4 3.4 10.0 3.5 14.4 5.4 2.4 2.4 19.3 17.9 22.8 28.1 21.6 16.6 20.8 19.2 18.1 12.8 18.3 18.1 37.5 16.0 17.9 10.1 36.5 21.9 17.8 14.9 10.8 43.6 28.9 26.8 14.2 10.0 14.9 11.0 41.7 12.2 91.7 36.9 9.8 17.1 254.8 37.7 32.5 24.7 30.5 12.6 10.8 29.5 18.9 21.6 31.1 32.4 29.9 41.8 16.8 16.4 14.9 25.2 9.8 26.6 6.1 21.9 30.3 613.6 20.5 32.3 14.2 14.0 16.4 21.6 41.2 5.5 6.2 30.1 24.0 18.8 38.2 28.8 15.0 14.6 22.8 39.3 13.1 26.4 23.0 16.0 13.2 19.0 25.3 18.2 46.2 51.7 24.8 32.8 CSRNP1 "AXUD1, DKFZp566F164, FAM130B, TAIP-3, URAX1" ENSG00000144655 "Cysteine and serine rich nuclear protein 1" Q96S65 3 39141855-39154562 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 193.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 17.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-BR-3: 64.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045207, HPA058463" Supported Nucleoplasm,Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Vesicles "HPA045207: AB_10967202, HPA058463: AB_2683726" "unprognostic (2.90e-2)" "unprognostic (6.89e-2)" "unprognostic (3.00e-1)" "unprognostic (1.15e-1)" "unprognostic (2.57e-1)" "unprognostic (1.46e-1)" "unprognostic (3.78e-2)" "unprognostic (1.90e-2)" "unprognostic (1.81e-2)" "unprognostic (1.34e-1)" "unprognostic (3.46e-1)" "unprognostic (1.39e-1)" "prognostic favorable (1.07e-4)" "prognostic unfavorable (6.47e-4)" "unprognostic (2.42e-2)" "unprognostic (1.98e-1)" "unprognostic (1.51e-1)" 88.9 55.8 13.6 34.0 13.7 193.1 51.7 17.2 22.5 34.7 15.4 35.6 12.0 30.2 6.4 61.7 79.8 67.5 49.9 12.8 18.0 29.2 67.3 80.8 14.9 21.3 16.2 41.5 39.4 23.5 43.3 25.0 15.7 32.7 15.4 5.8 21.3 18.5 36.9 57.1 26.4 64.1 18.3 20.3 48.0 14.7 17.1 34.9 33.8 19.0 8.7 51.6 27.7 15.4 4.4 9.7 2.5 4.8 4.7 4.9 7.8 15.9 22.1 13.0 10.6 13.7 4.0 14.4 3.3 12.1 9.3 4.9 3.0 21.0 6.4 21.6 4.0 16.4 8.0 10.5 5.8 4.1 15.7 2.3 11.3 20.4 3.2 11.6 17.8 3.9 12.7 24.9 10.7 13.9 0.8 6.7 11.4 7.4 8.1 6.8 10.4 23.7 10.3 15.9 7.0 1.1 8.7 64.2 5.5 14.5 7.2 7.5 9.0 6.6 28.2 5.6 11.9 6.3 5.8 6.6 14.4 5.2 8.4 0.1 3.0 3.8 1.7 5.9 2.1 3.6 1.6 2.0 3.3 3.7 2.0 1.3 17.1 2.6 11.0 4.2 2.7 2.3 13.6 13.7 17.2 22.5 12.8 18.0 21.3 16.2 15.7 18.3 17.1 15.4 200.8 48.1 66.3 6.8 75.0 103.2 88.1 40.2 153.1 1.4 121.1 95.8 15.8 37.1 31.2 11.0 0.0 19.7 86.3 77.3 9.8 37.6 54.4 119.6 65.2 92.8 59.3 13.2 3.5 38.5 43.0 98.1 75.4 199.4 96.5 4.2 73.9 40.7 38.7 0.0 1.5 54.7 22.4 36.7 165.2 46.8 1.5 94.5 69.4 4.7 14.8 7.6 7.2 1.5 1.3 49.2 60.9 4.1 74.3 49.4 54.1 6.0 21.0 1.7 13.1 154.4 103.9 0.6 4.7 85.7 79.6 90.7 132.4 8.9 38.0 38.9 CST3 ENSG00000101439 "Cystatin C" P01034 20 23626706-23638473 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Age-related macular degeneration, Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 4217.6" "Cell type enriched" "Detected in all" 4 "Langerhans cells: 18746.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "classical monocyte: 4967.5;intermediate monocyte: 6424.5;myeloid DC: 7959.0;non-classical monocyte: 4297.7;plasmacytoid DC: 4427.4" "Group enriched" "Detected in all" 9 "dendritic cells: 7959.0;monocytes: 6424.5" "Cell line enhanced" "Detected in many" "ASC diff: 1733.4;ASC TERT1: 1179.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000118, HPA013143" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 1040000000 2800000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Golgi apparatus, Vesicles" "CAB000118: , HPA013143: AB_1847417" "unprognostic (3.89e-2)" "unprognostic (1.63e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.83e-4)" "unprognostic (8.53e-2)" "unprognostic (4.06e-2)" "unprognostic (2.10e-2)" "unprognostic (2.18e-2)" "unprognostic (3.46e-2)" "unprognostic (3.72e-1)" "unprognostic (2.29e-3)" "unprognostic (3.51e-2)" "unprognostic (1.85e-1)" "unprognostic (1.16e-1)" "unprognostic (2.97e-1)" "unprognostic (5.01e-2)" "prognostic favorable (8.77e-4)" 1046.2 707.6 3041.2 262.3 3117.9 170.8 900.3 2823.3 4217.6 587.8 3094.8 788.7 389.6 708.3 875.9 557.1 802.7 583.0 1275.3 2976.3 2707.6 517.4 833.6 595.8 463.5 3258.4 3096.2 575.8 944.1 320.0 670.1 165.9 2939.3 773.9 416.9 46.9 2008.0 441.5 749.0 497.1 800.3 367.6 3028.1 723.7 979.9 761.3 3302.7 418.9 658.8 517.4 208.1 703.0 618.4 2883.1 155.2 328.2 75.4 175.8 1733.4 1179.8 145.3 261.4 350.7 170.3 137.7 625.1 219.7 0.8 241.0 345.2 221.3 496.2 69.6 499.9 51.9 0.9 253.5 157.6 61.1 1082.9 621.2 7.5 251.0 919.0 415.9 226.6 241.5 352.5 268.5 18.5 147.6 4.0 239.5 234.4 1.5 162.2 103.5 461.9 752.2 5.7 96.4 215.2 708.0 328.3 84.7 98.2 191.1 54.6 343.3 107.7 156.5 548.2 702.0 163.4 119.0 231.6 97.7 157.1 6.2 1.8 138.0 339.5 184.0 48.1 4967.5 33.2 66.9 6424.5 25.5 23.1 18.3 45.8 7959.0 13.6 16.9 31.1 809.3 191.4 4297.7 4427.4 13.6 4250.8 3041.2 3117.9 2823.3 4217.6 2976.3 2707.6 3258.4 3096.2 2939.3 3028.1 3302.7 2883.1 662.4 115.4 168.8 849.5 93.8 942.9 571.1 568.2 213.9 152.4 660.2 512.1 240.7 1361.2 514.5 641.9 29.2 476.8 603.3 1889.9 414.8 489.9 46.2 441.1 795.0 728.2 882.1 252.1 4.5 783.6 308.7 3026.2 981.7 631.0 359.9 687.0 491.9 2563.0 1816.7 48.8 11.2 1360.6 691.7 4301.1 18746.6 184.3 2132.6 4542.6 1563.5 87.1 2025.6 248.7 99.9 263.9 6.0 1458.5 2342.1 1790.4 67.9 786.0 4301.1 1098.6 364.4 36.3 2195.7 1417.0 846.2 125.5 400.6 461.5 822.0 469.0 117.4 208.1 1039.4 1079.7 CSTF2T "CstF-64T, DKFZp434C1013, KIAA0689, tauCstF-64" ENSG00000177613 "Cleavage stimulation factor subunit 2 tau variant" Q9H0L4 10 51695486-51699595 "Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039216, HPA062021" Approved Enhanced Nucleoplasm,Vesicles No No "Cluster 15: NK-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm Vesicles "HPA039216: AB_10795462, HPA062021: AB_2684662" "unprognostic (2.60e-2)" "unprognostic (3.75e-2)" "unprognostic (2.93e-2)" "unprognostic (2.17e-1)" "unprognostic (8.59e-2)" "unprognostic (1.06e-1)" "unprognostic (4.06e-3)" "unprognostic (9.13e-2)" "unprognostic (1.19e-1)" "unprognostic (3.42e-1)" "unprognostic (5.92e-2)" "unprognostic (5.36e-2)" "unprognostic (7.63e-2)" "unprognostic (5.19e-2)" "unprognostic (2.22e-1)" "unprognostic (3.31e-1)" "unprognostic (1.96e-1)" 13.5 13.2 10.6 17.4 13.1 13.6 11.7 13.4 13.4 11.0 11.2 10.4 11.7 11.7 10.3 9.0 14.8 10.2 14.4 10.4 11.5 11.9 12.6 9.6 19.6 13.3 12.6 17.9 12.3 18.0 6.0 11.9 13.1 11.9 10.6 13.8 10.7 9.3 22.2 10.9 11.6 12.2 13.9 17.6 11.1 9.5 12.0 21.5 11.5 22.8 19.4 12.4 6.3 18.4 16.2 18.9 27.9 29.4 38.5 26.2 1.9 22.5 20.7 25.4 24.7 25.3 23.2 46.5 12.7 19.7 15.4 24.8 21.2 23.6 22.9 27.1 24.0 26.8 19.9 4.7 18.6 10.5 23.6 38.0 18.0 22.4 25.8 16.1 19.3 26.9 29.3 25.6 22.2 13.9 42.9 16.8 10.3 19.7 40.3 33.7 56.2 9.9 19.6 13.4 23.3 30.1 18.8 19.4 20.4 28.9 36.2 19.2 20.7 16.2 22.1 15.1 28.5 32.5 13.0 32.9 33.7 24.1 14.3 2.8 4.1 4.5 3.5 3.8 4.9 1.7 2.6 2.8 4.3 3.0 4.4 4.0 1.1 10.9 2.8 2.7 4.6 2.9 10.6 13.1 13.4 13.4 10.4 11.5 13.3 12.6 13.1 13.9 12.0 18.4 13.4 9.6 7.5 2.9 15.8 9.1 7.1 15.7 12.5 18.2 8.7 5.6 14.3 8.6 11.1 9.2 8.4 24.1 13.7 7.5 23.5 16.4 1.7 9.2 13.5 17.7 6.1 17.7 4.6 15.3 14.6 12.4 9.7 7.8 20.3 10.9 17.9 16.7 15.4 20.2 5.7 8.7 10.2 14.8 8.3 2.7 23.9 8.9 0.0 3.7 22.5 13.2 33.0 3.0 19.3 13.9 6.1 19.9 7.1 4.1 9.3 13.6 17.8 13.7 6.6 16.1 9.1 37.0 15.7 8.5 6.5 6.2 17.2 12.0 11.2 5.1 CT55 "CXorf48, FLJ20527" ENSG00000169551 "Cancer/testis antigen 55" Q8WUE5 X 135156540-135171398 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "testis: 3.8" "Group enriched" "Detected in some" 46 "Spermatocytes: 43.8;Spermatogonia: 57.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 15 "K-562: 7.6" HPA059575 Approved Vesicles "Secreted in male reproductive system" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "HPA059575: " "unprognostic (6.20e-2)" "unprognostic (1.39e-1)" "unprognostic (8.36e-2)" "unprognostic (5.86e-3)" "unprognostic (3.47e-1)" "unprognostic (2.67e-1)" "unprognostic (4.44e-2)" "unprognostic (1.49e-1)" 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.4 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.8 57.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 CTAG2 "CAMEL, CT6.2a, CT6.2b, ESO2, LAGE-1, LAGE-1a, LAGE-1b, LAGE1, MGC138724, MGC3803" ENSG00000126890 "Cancer/testis antigen 2" O75638 X 154651972-154653579 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 5.4;testis: 10.4" "Cell type enriched" "Detected in some" 4 "Spermatogonia: 77.3" "Cancer enhanced" "Detected in many" "melanoma: 12.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 104.1;K-562: 140.6;OE19: 203.6;RPMI-8226: 311.3;SK-BR-3: 195.4;U-266/84: 356.9" "HPA071467, HPA076586" Enhanced Enhanced "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Vesicles" "Nuclear bodies" "HPA071467: AB_2686402, HPA076586: " "prognostic unfavorable (2.35e-4)" "unprognostic (3.87e-1)" "unprognostic (1.00e-1)" "unprognostic (1.25e-2)" 0.3 0.8 0.0 0.0 0.0 0.1 0.4 0.0 0.2 0.1 0.0 0.3 0.0 0.1 0.0 0.8 1.5 0.0 5.4 0.0 0.0 3.4 0.7 0.3 0.0 0.1 0.0 0.5 2.0 0.0 0.3 2.6 0.1 0.3 0.0 0.0 0.1 0.0 3.3 0.4 0.2 0.0 0.0 0.4 0.5 10.4 0.0 3.0 0.1 0.0 0.0 0.0 0.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 104.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 140.6 2.9 0.0 0.0 0.2 0.0 0.0 203.6 0.0 0.0 0.0 311.3 0.0 0.0 0.4 0.0 0.0 195.4 0.3 0.0 0.2 0.6 0.3 6.3 0.2 0.7 0.2 2.6 356.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.2 0.0 2.1 0.0 0.0 1.2 0.9 0.0 3.9 0.0 0.2 0.0 1.8 0.2 0.0 0.0 0.5 0.0 11.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 3.1 0.3 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 3.7 1.2 0.5 0.0 0.0 0.6 18.5 77.3 0.0 0.0 1.1 0.1 0.0 0.0 0.0 CTDP1 FCP1 ENSG00000060069 "CTD phosphatase subunit 1" Q9Y5B0 18 79679803-79754510 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cataract, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 113.1;Late spermatids: 123.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032641, HPA040394, HPA070389" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 24: NB-4 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm Vesicles "CAB032641: AB_2261235, HPA040394: AB_10794029, HPA070389: AB_2732155" "unprognostic (1.71e-1)" "unprognostic (1.75e-1)" "unprognostic (1.37e-1)" "prognostic favorable (6.43e-4)" "unprognostic (2.64e-2)" "unprognostic (7.99e-2)" "unprognostic (3.47e-3)" "unprognostic (1.83e-1)" "unprognostic (2.54e-1)" "unprognostic (1.15e-1)" "unprognostic (5.21e-3)" "unprognostic (1.99e-2)" "prognostic favorable (5.51e-5)" "unprognostic (5.16e-2)" "unprognostic (8.58e-2)" "unprognostic (2.85e-2)" "unprognostic (4.74e-2)" 9.3 7.4 3.8 7.2 3.9 13.7 8.9 3.3 4.2 7.8 4.1 11.1 7.2 10.4 1.4 10.7 8.1 4.0 7.2 3.3 3.3 7.9 9.5 9.3 8.7 5.3 4.2 5.0 9.0 3.3 6.9 4.2 4.0 8.2 3.1 1.5 9.5 3.9 11.9 20.5 10.9 3.1 3.3 13.5 9.9 22.2 4.0 6.5 8.0 3.1 3.7 9.6 8.6 4.4 13.4 14.0 7.7 11.0 6.0 5.0 25.9 9.6 6.1 7.6 7.5 9.4 8.0 17.2 4.2 5.6 9.1 16.4 6.6 8.8 3.1 16.9 12.4 8.5 6.6 12.9 8.7 37.6 20.5 8.4 8.3 8.1 3.8 4.6 9.2 12.2 11.2 8.1 3.0 11.5 25.4 29.5 12.7 4.2 19.1 20.7 10.1 20.0 5.6 13.1 12.0 12.4 10.2 9.8 13.9 5.8 8.0 21.7 12.9 12.9 19.4 5.3 9.7 7.4 27.6 16.1 11.0 18.8 9.3 0.0 0.4 3.2 0.5 0.4 0.4 0.2 0.4 0.8 0.6 0.1 0.5 0.3 1.0 1.1 0.4 0.1 0.1 0.2 3.8 3.9 3.3 4.2 3.3 3.3 5.3 4.2 4.0 3.3 4.0 4.4 7.4 0.0 4.1 3.6 9.2 8.5 5.0 4.0 11.4 9.5 7.7 6.5 3.8 4.3 4.5 3.7 14.6 8.8 24.2 20.0 1.9 5.4 113.1 18.6 8.0 7.5 6.0 13.5 7.7 7.2 8.0 4.8 19.9 24.0 7.0 7.8 6.4 5.7 8.8 23.5 6.6 16.6 6.1 7.5 9.5 123.2 7.8 13.8 7.2 6.5 6.5 6.5 19.6 3.0 8.9 10.2 14.9 10.5 15.2 11.8 10.0 6.8 9.6 14.8 0.0 5.9 7.4 18.0 10.5 10.5 10.1 19.0 18.3 8.0 11.7 12.6 CTDSPL "C3orf8, HYA22, PSR1, RBSP3, SCP3" ENSG00000144677 "CTD small phosphatase like" O15194 3 37861880-37984469 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 170.4;Excitatory neurons: 189.3;Inhibitory neurons: 126.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 132.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048325 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles Nucleoplasm "HPA048325: AB_2680359" "unprognostic (7.35e-2)" "unprognostic (1.36e-1)" "unprognostic (1.21e-1)" "unprognostic (6.48e-3)" "unprognostic (1.73e-1)" "unprognostic (3.35e-2)" "unprognostic (1.66e-3)" "unprognostic (4.30e-2)" "unprognostic (1.96e-1)" "unprognostic (2.55e-1)" "unprognostic (2.98e-3)" "unprognostic (1.20e-1)" "prognostic favorable (6.22e-14)" "unprognostic (3.48e-2)" "unprognostic (6.84e-2)" "unprognostic (1.94e-1)" "unprognostic (2.67e-2)" 21.1 9.2 19.4 6.3 20.6 10.0 28.1 24.3 23.2 20.3 17.1 33.4 14.3 20.2 14.0 23.8 17.9 29.3 29.4 18.8 17.3 39.7 21.5 27.2 4.1 19.2 17.7 19.6 15.8 12.0 10.7 31.7 16.6 26.5 30.2 3.2 27.1 31.3 21.2 52.9 17.6 23.2 18.1 17.3 31.7 10.6 19.5 7.2 14.0 19.9 5.5 26.4 19.1 17.3 44.5 18.9 7.6 24.0 29.2 41.0 57.2 30.0 37.0 20.1 23.5 27.4 35.3 0.2 17.9 36.9 8.4 36.3 19.2 56.1 16.0 0.1 15.1 27.2 18.8 63.1 26.4 0.0 6.4 21.5 132.3 21.2 25.5 22.4 28.2 12.0 8.9 0.0 33.7 13.7 11.1 0.1 31.5 17.7 2.7 12.3 14.9 0.2 63.3 28.7 6.3 19.9 16.5 28.7 33.5 30.5 28.1 7.3 23.2 14.4 20.4 27.3 19.1 0.6 0.2 0.2 15.8 14.8 27.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 2.1 19.4 20.6 24.3 23.2 18.8 17.3 19.2 17.7 16.6 18.1 19.5 17.3 26.8 67.3 27.6 170.4 1.2 30.1 17.0 17.7 27.9 10.1 25.7 59.4 42.2 65.8 25.7 23.9 0.0 34.7 1.0 35.6 23.5 14.2 21.5 7.6 17.6 22.4 45.2 7.8 189.3 4.7 9.9 32.4 10.2 27.2 1.3 15.7 22.9 18.1 7.2 10.1 126.3 18.5 2.0 13.3 6.5 51.3 71.7 11.3 8.8 22.5 1.4 9.5 1.0 87.4 48.8 14.2 17.9 98.2 0.4 15.5 9.1 19.7 12.4 1.7 26.3 55.4 40.4 10.0 16.9 17.7 28.7 9.4 2.0 65.8 42.0 14.4 CTNNBIP1 "ICAT, MGC15093" ENSG00000178585 "Catenin beta interacting protein 1" Q9NSA3 1 9848276-9910336 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 177.7;skin 1: 434.9" "Cell type enhanced" "Detected in many" "Muller glia cells: 185.7;Suprabasal keratinocytes: 291.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 13.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067089 Enhanced Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA 35000 "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Cytosol" "Nucleoli, Vesicles" "HPA067089: " "unprognostic (2.71e-1)" "unprognostic (4.46e-2)" "unprognostic (1.94e-1)" "prognostic favorable (5.68e-6)" "unprognostic (3.08e-1)" "unprognostic (2.63e-2)" "unprognostic (2.22e-2)" "unprognostic (1.19e-1)" "unprognostic (2.23e-2)" "unprognostic (2.62e-1)" "unprognostic (2.17e-2)" "unprognostic (1.77e-1)" "unprognostic (1.24e-3)" "unprognostic (3.62e-2)" "unprognostic (3.22e-2)" "unprognostic (8.63e-2)" "unprognostic (4.37e-2)" 34.4 11.1 29.7 11.2 28.2 22.4 35.2 37.3 31.2 59.2 13.1 15.0 18.8 11.8 77.4 177.7 12.5 10.3 43.8 29.5 30.0 17.6 15.7 26.4 8.7 33.8 29.0 14.6 35.9 10.9 19.7 28.2 36.4 24.5 10.2 27.5 53.1 14.1 39.0 434.9 14.9 10.9 27.1 9.3 22.8 27.0 37.5 19.6 21.0 22.3 25.1 13.3 85.1 27.3 74.8 10.9 65.9 50.4 9.8 16.2 21.1 14.4 25.2 20.9 13.3 5.4 92.6 22.9 41.0 18.7 21.6 37.3 7.7 85.9 9.6 58.0 11.9 14.9 3.4 69.3 20.3 11.3 8.4 18.2 83.5 26.7 27.0 17.7 57.2 42.4 26.8 10.5 13.0 45.6 25.3 41.6 35.0 60.0 18.7 28.4 19.3 14.7 10.7 25.2 72.1 45.4 32.9 29.4 44.4 22.3 36.3 27.2 37.7 13.4 16.4 20.4 32.2 22.9 32.5 27.0 5.0 56.6 54.5 2.6 5.2 13.8 2.6 1.8 1.6 1.7 1.3 2.1 6.4 1.5 1.3 1.2 3.7 8.6 1.2 2.0 1.3 2.6 29.7 28.2 37.3 31.2 29.5 30.0 33.8 29.0 36.4 27.1 37.5 27.3 150.6 28.9 13.9 30.0 9.6 103.1 42.3 16.1 40.5 9.0 39.9 33.3 14.0 24.3 17.0 18.4 8.4 71.3 23.5 20.5 33.2 20.9 116.3 20.0 17.9 42.7 49.1 20.0 18.0 18.7 43.2 15.7 30.1 38.5 0.0 27.2 20.0 25.6 58.0 16.8 14.1 37.5 12.2 43.0 97.4 34.8 14.9 38.3 48.0 12.2 33.6 185.7 71.1 17.1 24.1 37.6 28.3 23.0 13.3 53.5 28.6 30.5 5.2 12.8 46.0 15.0 24.5 72.1 43.6 154.0 291.5 48.4 17.2 14.3 28.6 60.5 CTNS "CTNS-LSB, PQLC4, SLC66A4" ENSG00000040531 "Cystinosin, lysosomal cystine transporter" O60931 17 3636459-3663103 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Melanin biosynthesis, Protein transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 35.5;Late spermatids: 29.3;Theca cells: 30.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 34.3;granulocytes: 27.9;monocytes: 10.4" "Cell line enhanced" "Detected in all" "HDLM-2: 144.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046947 Supported "Vesicles,Intermediate filaments" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Intermediate filaments" "HPA046947: AB_2679872" "unprognostic (1.64e-1)" "unprognostic (1.70e-1)" "unprognostic (1.21e-1)" "unprognostic (8.25e-2)" "unprognostic (8.39e-2)" "prognostic favorable (7.33e-4)" "unprognostic (1.28e-2)" "unprognostic (8.02e-2)" "unprognostic (1.94e-1)" "unprognostic (6.62e-3)" "prognostic favorable (6.39e-5)" "unprognostic (8.40e-2)" "unprognostic (2.25e-1)" "unprognostic (1.80e-1)" "unprognostic (5.64e-2)" "unprognostic (1.96e-1)" "unprognostic (1.52e-1)" 10.3 19.5 9.5 10.0 17.0 10.2 9.6 13.5 12.1 20.3 12.1 8.3 12.2 11.3 6.4 8.7 10.3 13.1 10.5 10.8 10.3 15.2 15.9 11.6 10.0 16.5 16.8 12.1 27.0 13.6 9.6 12.9 18.0 10.8 7.2 6.8 12.0 11.6 15.3 19.2 11.0 8.6 10.9 12.1 15.0 24.8 13.2 8.8 9.2 7.4 9.5 9.1 9.4 28.0 17.6 37.0 22.6 18.2 34.5 16.9 13.0 19.6 28.8 21.1 26.0 21.0 16.0 10.2 17.8 11.6 55.9 40.1 19.8 12.1 12.6 144.3 33.7 10.8 32.2 19.3 46.5 8.0 81.3 23.8 14.2 20.2 15.4 28.1 22.2 18.7 12.6 15.9 16.6 15.1 7.8 7.9 9.8 12.2 16.8 16.4 9.3 23.0 15.3 16.2 3.9 17.2 19.2 24.4 20.3 19.0 17.1 7.7 24.2 17.2 11.6 40.3 13.3 12.4 20.0 4.2 28.1 7.8 11.8 27.9 10.4 21.8 3.0 6.9 4.9 5.8 4.0 5.7 9.7 4.9 4.5 5.5 3.1 5.2 7.1 34.3 4.3 7.3 9.5 17.0 13.5 12.1 10.8 10.3 16.5 16.8 18.0 10.9 13.2 28.0 4.4 3.2 2.2 6.5 4.8 1.7 3.5 2.5 4.0 1.6 6.3 5.0 5.2 5.7 2.7 12.9 10.4 6.1 5.2 3.6 0.0 6.7 35.5 5.7 4.4 5.3 2.4 4.0 3.4 6.4 7.1 6.0 7.7 4.3 8.2 6.7 9.3 7.6 25.2 5.0 3.4 2.5 4.1 7.2 5.9 29.3 9.6 12.1 5.4 3.7 10.0 6.5 3.1 5.5 11.1 6.4 3.3 12.8 4.5 6.5 3.2 9.5 7.0 3.9 6.6 3.7 3.5 19.7 8.7 2.9 2.4 8.5 3.3 30.9 1.8 3.2 CTSA "GSL, PPGB" ENSG00000064601 "Cathepsin A" P10619 20 45890144-45898824 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 368.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 445.6;Proximal enterocytes: 301.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 856.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024930, HPA031068, HPA072487" Enhanced Enhanced Vesicles "Intracellular and membrane" NA NA 28000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "CAB024930: , HPA031068: AB_10601205, HPA072487: " "unprognostic (8.61e-2)" "unprognostic (3.37e-1)" "unprognostic (4.30e-2)" "unprognostic (2.13e-1)" "unprognostic (6.42e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.95e-4)" "unprognostic (6.33e-2)" "unprognostic (9.53e-3)" "unprognostic (7.19e-2)" "unprognostic (1.83e-1)" "unprognostic (6.85e-2)" "unprognostic (7.57e-2)" "unprognostic (1.09e-1)" "unprognostic (6.05e-2)" "unprognostic (1.71e-1)" "unprognostic (8.40e-2)" 80.4 368.3 56.8 75.3 58.1 75.6 61.9 63.6 65.6 47.6 96.0 178.6 100.9 55.1 39.0 60.4 39.3 89.7 97.2 59.7 63.8 188.1 95.7 90.9 61.6 62.6 59.1 62.2 52.9 104.4 43.8 76.4 61.4 38.5 170.4 44.0 61.3 48.4 56.0 95.2 109.2 67.3 59.4 108.5 63.3 33.5 70.2 23.0 47.4 61.7 58.8 82.8 49.2 68.4 111.9 114.1 17.6 89.2 856.5 438.6 47.0 150.3 424.0 169.6 217.5 214.4 291.8 24.1 176.2 299.9 638.1 168.6 55.9 105.6 95.7 47.6 53.6 54.3 53.4 375.9 187.3 98.0 240.9 349.0 123.6 107.9 22.5 421.9 190.1 28.2 61.0 355.1 186.9 232.1 25.8 82.4 19.4 172.6 272.1 37.8 107.3 135.7 138.2 96.7 36.9 37.8 263.2 450.3 444.4 51.5 108.5 141.8 172.5 335.0 76.2 178.9 123.7 162.1 238.5 15.7 599.3 128.6 142.4 480.7 305.9 530.5 44.9 168.8 185.5 42.0 75.6 78.3 102.4 25.7 26.6 39.8 152.4 81.2 120.1 40.6 155.4 378.1 56.8 58.1 63.6 65.6 59.7 63.8 62.6 59.1 61.4 59.4 70.2 68.4 53.7 35.3 32.6 26.1 38.2 24.2 38.9 88.8 17.6 58.4 18.4 15.9 12.6 65.8 64.1 71.7 60.5 104.1 27.5 445.6 39.2 246.0 3.3 22.3 39.5 56.0 54.0 22.1 20.4 166.4 109.2 86.8 29.6 62.4 9.5 50.8 102.1 67.9 297.1 47.1 25.2 74.5 95.6 177.1 25.1 4.8 32.9 273.1 112.1 12.2 135.6 86.6 37.0 7.1 10.2 135.0 216.0 27.4 41.9 18.6 301.8 245.8 34.2 46.1 26.3 33.7 54.5 15.3 31.9 24.0 22.9 144.1 49.1 91.3 113.9 36.2 CTSB ENSG00000164733 "Cathepsin B" P07858 8 11842524-11869533 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2744.5;Kupffer cells: 1774.9;Macrophages: 1224.3" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 1446.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 390.6;classical monocyte: 610.1;intermediate monocyte: 467.3;myeloid DC: 287.4;non-classical monocyte: 307.6;plasmacytoid DC: 410.1" "Group enriched" "Detected in all" 6 "dendritic cells: 410.1;granulocytes: 390.6;monocytes: 610.1" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1607.5;fHDF/TERT166: 1436.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000457, HPA018156, HPA048998" Enhanced Supported Nucleoli,Vesicles "Secreted to blood" NA NA 100000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoli "CAB000457: , HPA018156: AB_1846069, HPA048998: " "unprognostic (5.74e-2)" "unprognostic (4.32e-2)" "unprognostic (1.38e-2)" "unprognostic (2.17e-2)" "unprognostic (2.98e-3)" "unprognostic (5.96e-2)" "unprognostic (1.36e-2)" "unprognostic (1.07e-1)" "unprognostic (2.82e-2)" "unprognostic (1.06e-1)" "unprognostic (7.61e-2)" "unprognostic (8.30e-2)" "unprognostic (2.85e-1)" "unprognostic (7.39e-2)" "unprognostic (4.12e-2)" "prognostic favorable (5.76e-4)" "prognostic unfavorable (9.02e-4)" 443.9 304.5 65.6 399.7 71.2 87.0 249.0 65.9 77.2 583.2 101.0 312.4 120.8 379.2 116.9 421.6 368.4 230.6 447.0 64.7 95.5 420.6 497.2 428.9 289.6 100.4 90.8 169.1 135.4 79.6 156.8 253.2 107.4 255.5 159.3 33.6 437.3 156.6 237.4 184.7 260.2 316.1 91.9 521.1 194.3 33.2 204.5 60.9 1150.7 99.3 104.0 431.9 477.8 159.2 66.6 283.4 4.0 94.9 657.3 754.5 128.3 885.0 1607.5 258.4 299.5 10.3 294.4 1.5 32.2 1436.1 419.3 279.5 65.3 157.1 195.6 25.9 52.6 58.8 10.0 397.1 479.2 7.7 73.7 296.4 532.2 327.2 427.3 611.5 33.4 20.2 81.7 260.7 194.6 62.5 6.5 23.1 16.3 839.7 91.3 33.6 39.3 202.7 2.6 121.1 4.9 68.6 165.1 68.6 514.6 110.1 97.8 68.7 922.4 766.5 111.9 129.9 259.3 182.7 178.5 4.8 432.5 22.9 249.4 390.6 610.1 90.6 26.3 467.3 35.4 44.1 79.0 31.5 287.4 38.8 48.3 21.5 97.8 31.3 307.6 410.1 78.7 703.7 65.6 71.2 65.9 77.2 64.7 95.5 100.4 90.8 107.4 91.9 204.5 159.2 87.7 109.0 171.4 17.6 54.8 54.7 441.6 563.2 54.7 55.2 94.1 74.5 320.1 165.8 331.7 114.0 41.7 279.4 122.4 147.9 27.4 294.6 15.6 105.8 240.1 163.0 154.7 210.2 36.2 238.2 341.7 155.0 44.4 183.5 179.4 105.9 204.2 239.5 2744.5 58.9 42.8 94.2 158.7 1774.9 436.5 18.5 76.4 1224.3 161.9 70.3 373.1 117.4 24.7 19.1 12.9 363.9 154.0 92.9 47.3 295.5 198.6 351.8 180.8 40.0 39.5 39.4 149.9 10.8 21.0 160.3 40.5 649.6 56.0 32.1 139.6 321.4 CTSC "DPP1, PALS, PLS" ENSG00000109861 "Cathepsin C" P53634 11 88265069-88359684 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 900.7;Club cells: 471.8;Hofbauer cells: 1100.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 1078.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025364, HPA066610, HPA068434" Enhanced Supported Vesicles "Intracellular and membrane" No No 19000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "CAB025364: , HPA066610: AB_2685694, HPA068434: AB_2685989" "unprognostic (4.05e-2)" "unprognostic (1.35e-1)" "unprognostic (1.50e-1)" "unprognostic (1.10e-1)" "unprognostic (3.70e-2)" "unprognostic (1.45e-2)" "prognostic unfavorable (9.30e-5)" "unprognostic (1.62e-1)" "unprognostic (1.04e-1)" "unprognostic (1.56e-2)" "unprognostic (3.11e-2)" "unprognostic (3.35e-1)" "prognostic favorable (4.80e-4)" "unprognostic (2.93e-1)" "unprognostic (4.35e-2)" "unprognostic (8.10e-2)" "unprognostic (4.07e-2)" 173.2 60.7 9.9 185.1 9.6 71.7 63.4 11.1 24.9 77.9 14.2 143.1 121.0 43.9 28.5 63.3 54.0 182.0 38.5 9.5 10.1 234.7 82.0 272.6 243.7 14.0 11.9 22.1 52.2 42.4 39.3 253.3 13.3 26.0 191.5 3.7 131.6 28.9 18.8 29.6 128.8 88.9 11.5 197.2 73.6 22.8 19.5 63.7 43.6 31.9 140.6 176.3 43.3 21.3 80.3 75.9 27.6 69.9 103.7 286.1 218.4 626.5 1078.4 372.8 270.3 194.7 361.3 117.3 278.9 365.2 84.3 133.6 50.4 269.2 341.9 204.7 82.8 144.5 188.0 233.5 140.2 188.9 108.7 419.1 198.8 284.5 697.4 302.1 377.6 122.3 155.3 145.4 54.8 14.8 89.1 295.1 172.2 551.5 244.9 113.6 30.7 227.0 451.3 106.6 8.8 66.8 81.2 114.9 80.6 185.4 27.9 152.7 149.3 23.5 190.5 156.8 364.6 61.9 81.0 122.9 56.8 435.8 122.4 85.5 203.8 309.7 230.1 415.6 194.9 47.2 99.6 198.2 209.9 26.3 49.5 115.3 215.0 200.5 582.9 425.0 162.7 243.3 9.9 9.6 11.1 24.9 9.5 10.1 14.0 11.9 13.3 11.5 19.5 21.3 78.6 22.4 88.1 0.3 40.8 30.1 7.3 900.7 33.6 1.5 15.9 14.6 4.4 52.9 471.8 40.5 0.0 414.1 330.6 37.9 29.4 29.8 1.6 13.4 135.6 94.8 11.4 29.7 3.0 90.6 159.2 114.4 39.8 21.2 75.3 25.5 26.4 15.8 1100.6 0.0 8.2 19.4 158.7 344.7 200.7 7.9 198.5 391.7 48.0 61.8 185.4 0.5 299.7 13.6 0.4 44.8 72.3 25.6 78.5 8.5 20.2 166.4 93.7 0.8 59.2 4.4 150.8 3.0 11.1 43.3 27.1 227.3 170.6 286.7 44.9 16.1 CTSE ENSG00000196188 "Cathepsin E" P14091 1 206008535-206023909 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 1168.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 105.8;Exocrine glandular cells: 262.8;Gastric mucus-secreting cells: 553.5;Pancreatic endocrine cells: 260.0;Paneth cells: 208.9" "Cancer enhanced" "Detected in many" "pancreatic cancer: 297.4;stomach cancer: 200.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 46 "OE19: 1799.1" "Not detected" "Not detected" "HPA012674, HPA012940, CAB032687" Enhanced Approved Vesicles "Intracellular and membrane" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB032687: AB_637901, HPA012674: , HPA012940: AB_2668773" "unprognostic (1.17e-2)" "unprognostic (2.45e-1)" "unprognostic (1.31e-2)" "unprognostic (2.72e-2)" "unprognostic (1.35e-2)" "unprognostic (2.52e-3)" "unprognostic (1.45e-1)" "unprognostic (3.29e-2)" "unprognostic (2.87e-2)" "unprognostic (1.20e-2)" "unprognostic (1.39e-1)" "unprognostic (6.37e-3)" "unprognostic (1.42e-1)" "unprognostic (5.45e-2)" "unprognostic (2.61e-2)" "prognostic favorable (5.26e-5)" 0.3 0.0 0.1 9.5 0.1 30.0 0.0 0.5 0.3 0.0 0.1 15.3 229.8 0.3 1.7 0.8 1.1 15.0 0.3 0.1 0.1 0.2 0.2 49.7 0.5 0.3 0.1 0.1 3.7 0.0 1.1 1.3 0.3 0.2 25.7 0.1 0.0 1.6 0.0 0.1 55.5 0.3 0.1 0.6 1168.3 0.1 0.3 0.5 8.9 0.0 10.7 5.8 0.2 0.5 0.3 0.0 0.0 0.0 0.0 0.0 20.2 0.0 0.0 0.0 0.0 0.8 0.8 0.0 3.8 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.7 0.2 2.4 0.0 1.0 3.9 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.8 1.5 0.7 1799.1 0.1 0.4 0.0 0.8 0.7 39.4 0.2 0.5 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 0.7 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.2 0.5 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.3 0.2 0.1 0.6 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.5 0.3 0.1 0.1 0.3 0.1 0.3 0.1 0.3 0.5 0.0 105.8 27.9 0.0 0.6 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.5 10.0 42.3 0.0 0.0 0.0 0.0 34.1 0.0 52.0 0.0 0.3 0.0 0.3 2.4 60.6 0.0 262.8 0.1 14.7 553.5 0.6 0.0 0.0 0.0 0.2 0.2 0.0 0.0 21.1 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 1.6 0.0 0.0 0.0 0.1 260.0 208.9 0.0 0.7 0.1 4.0 0.1 7.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.1 10.4 0.4 CTSF "CATSF, CLN13" ENSG00000174080 "Cathepsin F" Q9UBX1 11 66563464-66568879 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 320.9;Muller glia cells: 196.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SiHa: 23.1;SK-MEL-30: 59.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002141, HPA031431" Approved Supported "Endoplasmic reticulum,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 5800000 "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Endoplasmic reticulum, Plasma membrane" "CAB002141: AB_563471, HPA031431: " "unprognostic (1.52e-2)" "unprognostic (1.08e-1)" "unprognostic (1.03e-1)" "unprognostic (7.22e-3)" "unprognostic (2.25e-2)" "unprognostic (6.72e-2)" "unprognostic (2.67e-2)" "unprognostic (2.76e-2)" "unprognostic (3.69e-1)" "unprognostic (4.14e-1)" "unprognostic (1.69e-2)" "unprognostic (9.12e-2)" "prognostic favorable (8.92e-7)" "unprognostic (1.36e-2)" "unprognostic (1.28e-1)" "unprognostic (3.89e-1)" "unprognostic (2.42e-1)" 57.8 70.0 68.1 0.8 76.3 0.3 62.2 74.5 74.0 78.8 90.2 76.7 3.0 89.2 21.9 15.6 70.8 10.0 100.2 63.2 74.2 46.9 66.0 32.9 3.6 75.0 70.3 99.1 31.7 20.0 43.3 3.8 68.4 53.5 3.5 26.2 55.7 17.1 91.9 44.4 29.5 12.2 77.2 25.0 54.3 109.7 71.0 3.0 40.6 27.6 3.0 56.6 58.7 86.6 0.0 17.0 3.1 5.4 14.2 8.6 3.4 13.0 11.4 6.3 2.3 0.0 2.2 0.0 21.3 10.4 0.0 1.2 6.8 2.6 4.8 3.7 0.0 0.5 7.0 0.0 9.9 0.3 4.4 22.3 9.1 0.8 1.6 13.7 3.8 2.0 5.4 1.6 5.2 4.6 0.1 1.7 0.9 3.7 9.7 0.0 0.0 1.5 7.1 0.3 4.3 6.9 23.1 0.3 59.5 0.3 7.4 0.6 3.3 1.8 2.9 1.5 1.2 21.2 0.2 0.0 2.2 0.0 2.9 0.0 0.4 0.3 3.9 0.6 4.1 1.5 3.5 4.6 0.6 1.4 6.4 4.1 0.1 4.6 0.2 0.9 1.3 2.2 68.1 76.3 74.5 74.0 63.2 74.2 75.0 70.3 68.4 77.2 71.0 86.6 36.6 12.8 15.6 31.3 5.9 39.8 62.4 8.5 37.5 107.9 45.3 80.6 57.9 41.5 7.4 36.8 41.7 31.6 9.6 0.6 15.6 13.1 163.3 1.7 22.8 27.2 12.0 11.4 26.5 7.5 9.5 118.1 8.2 5.3 9.5 52.1 56.0 67.8 14.9 134.6 31.3 3.1 18.3 21.5 32.8 320.9 145.7 13.1 156.5 12.2 3.1 196.6 17.5 21.6 29.4 5.9 3.2 121.9 12.9 50.5 1.3 44.7 3.3 77.9 78.9 62.0 45.9 169.6 43.3 3.6 25.3 23.7 9.5 30.7 4.3 32.9 CTSH "ACC-4, ACC-5, ACC4, ACC5, CPSB" ENSG00000103811 "Cathepsin H" P09668 15 78921058-78949574 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 349.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1569.9;Proximal tubular cells: 523.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 208.5;intermediate monocyte: 137.7;memory B-cell: 83.3;myeloid DC: 183.6;naive B-cell: 56.0;non-classical monocyte: 94.8" "Group enriched" "Detected in all" 5 "B-cells: 83.3;dendritic cells: 183.6;monocytes: 208.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 306.4;HaCaT: 228.2;HDLM-2: 183.0;OE19: 197.4;RT4: 362.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000458, HPA003524" Enhanced Supported "Vesicles,Cytosol,Cytoplasmic bodies" "Intracellular and membrane" NA NA 8700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Vesicles, Cytosol, Cytoplasmic bodies" "CAB000458: , HPA003524: AB_1846075" "unprognostic (6.47e-2)" "unprognostic (4.65e-3)" "unprognostic (1.05e-1)" "prognostic favorable (6.90e-4)" "unprognostic (4.37e-2)" "unprognostic (1.93e-1)" "unprognostic (7.18e-2)" "unprognostic (3.30e-3)" "unprognostic (2.22e-1)" "unprognostic (5.96e-2)" "unprognostic (4.10e-2)" "unprognostic (3.89e-2)" "unprognostic (6.63e-3)" "unprognostic (3.83e-1)" "unprognostic (4.42e-2)" "unprognostic (2.70e-3)" "unprognostic (1.79e-3)" 34.3 36.4 29.4 100.6 30.2 36.9 48.8 29.9 47.1 112.8 31.4 32.5 77.8 46.7 26.8 37.9 57.6 104.6 51.3 29.6 32.9 238.2 89.5 349.6 191.8 30.8 31.4 30.0 75.5 77.6 10.1 25.7 31.5 59.7 27.3 4.7 63.0 70.7 16.3 48.4 56.7 43.1 30.7 51.8 93.9 10.1 32.7 51.8 27.7 37.7 131.3 202.2 30.6 32.4 122.0 10.0 1.2 30.5 5.4 0.5 20.3 8.6 3.0 13.9 7.0 17.6 306.4 34.6 12.6 0.0 13.5 228.2 5.2 52.6 10.1 183.0 0.4 3.0 1.3 38.4 12.1 0.4 7.1 5.6 10.7 0.2 0.0 59.4 1.0 5.9 76.0 0.0 17.9 2.8 32.6 87.8 8.9 197.4 4.9 0.3 0.4 5.9 49.9 362.1 2.6 5.2 41.5 27.8 75.4 10.1 12.5 48.0 16.4 0.2 6.2 0.0 5.3 0.8 92.4 19.5 0.1 89.2 12.3 0.0 208.5 2.0 7.6 137.7 29.7 83.3 20.5 7.4 183.6 56.0 1.8 3.8 8.7 3.2 94.8 22.9 18.3 147.5 29.4 30.2 29.9 47.1 29.6 32.9 30.8 31.4 31.5 30.7 32.7 32.4 169.8 237.2 1569.9 59.1 127.4 24.2 280.7 363.9 30.1 1.3 45.5 41.7 26.2 358.9 258.7 367.8 4.2 19.8 8.1 9.1 84.1 225.0 25.3 67.0 86.0 124.5 9.1 3.0 2.2 142.0 39.6 53.8 106.0 42.8 32.8 2.7 14.3 115.5 256.7 0.0 2.9 18.6 101.7 177.8 259.6 22.6 73.0 350.4 80.0 15.9 360.9 22.6 5.2 1.5 1.1 84.6 16.0 6.0 155.8 112.0 153.0 523.2 261.6 6.6 19.7 4.5 22.3 12.3 56.4 41.6 18.6 23.4 29.4 17.8 40.1 340.4 CTSK "CTSO, CTSO2, PKND, PYCD" ENSG00000143387 "Cathepsin K" P43235 1 150794880-150809577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 420.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 372.4;Langerhans cells: 123.6;Leydig cells: 119.0;Melanocytes: 97.8;Peritubular cells: 149.7;Theca cells: 80.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebral cortex: 18.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8" "Lineage enriched" "Detected in single" 4 "monocytes: 1.8" "Group enriched" "Detected in many" 9 "ASC diff: 2284.0;ASC TERT1: 813.2;BJ hTERT+: 1949.1" "Low region specificity" "Detected in all" HPA050346 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA050346: AB_2681101" "unprognostic (1.48e-1)" "unprognostic (9.29e-2)" "unprognostic (1.21e-1)" "unprognostic (7.61e-3)" "unprognostic (5.08e-2)" "unprognostic (6.57e-2)" "unprognostic (1.02e-1)" "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.49e-1)" "unprognostic (3.54e-2)" "prognostic unfavorable (7.12e-5)" "unprognostic (6.07e-3)" "unprognostic (2.98e-2)" "unprognostic (5.93e-3)" "unprognostic (6.41e-2)" 224.1 12.5 2.7 33.1 2.8 3.1 227.7 2.9 18.1 420.6 16.4 68.6 13.8 334.0 44.9 46.0 74.0 299.2 35.8 2.7 2.6 12.7 9.0 36.4 42.1 2.7 2.7 78.4 10.6 6.1 14.6 18.9 2.6 34.1 61.8 6.9 53.3 38.0 15.7 219.8 63.8 141.6 2.8 20.2 41.7 15.1 2.7 12.3 34.7 46.3 48.7 210.5 176.2 2.9 0.7 0.3 1.4 0.8 2284.0 813.2 1.0 55.2 1949.1 3.3 8.3 0.3 0.3 0.4 0.6 129.8 0.0 0.6 0.3 0.4 1.2 0.4 0.4 1.4 0.5 0.0 11.0 0.2 1.3 156.5 1.7 50.5 0.7 137.6 4.2 0.6 0.4 1.4 1.5 1.4 0.0 3.0 10.2 1.0 0.0 0.2 0.1 0.1 3.2 0.1 0.6 2.9 0.4 0.0 29.3 3.9 1.0 1.5 1.0 0.7 0.5 0.6 0.6 2.3 1.7 3.6 184.1 0.0 9.9 0.0 1.8 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.4 0.6 2.7 2.8 2.9 18.1 2.7 2.6 2.7 2.7 2.6 2.8 2.7 2.9 17.9 3.2 4.6 2.6 1.1 68.8 0.5 1.6 2.2 12.1 3.7 9.5 2.0 1.5 3.9 3.7 4.2 1.3 2.8 1.5 0.0 1.0 0.9 2.5 59.0 10.2 1.2 0.8 5.0 0.2 2.5 372.4 11.2 3.8 0.0 77.5 14.6 0.5 21.4 3.3 7.7 1.6 8.2 4.6 123.6 4.4 119.0 8.7 97.8 7.5 4.9 2.7 3.1 7.1 2.5 1.4 1.4 149.7 0.8 1.0 1.4 0.1 2.2 7.7 13.1 4.5 33.9 1.4 1.0 2.6 59.1 1.0 5.4 80.9 1.0 0.7 CTSL "CTSL1, FLJ31037" ENSG00000135047 "Cathepsin L" P07711 9 87724051-87731469 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 563.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1081.6;Extravillous trophoblasts: 1012.3;Hepatic stellate cells: 580.4;Hofbauer cells: 1105.7;Macrophages: 537.2;Syncytiotrophoblasts: 1543.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "intermediate monocyte: 128.1;non-classical monocyte: 195.2" "Lineage enriched" "Detected in many" 12 "monocytes: 195.2" "Cell line enhanced" "Detected in many" "ASC TERT1: 2305.0;HSkMC: 1061.0" "Low region specificity" "Detected in all" "CAB000459, HPA070413" Enhanced Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 17000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "CAB000459: AB_2292484, HPA070413: " "unprognostic (1.05e-1)" "unprognostic (1.01e-1)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.73e-4)" "unprognostic (1.19e-3)" "unprognostic (8.12e-3)" "prognostic unfavorable (5.15e-5)" "unprognostic (2.09e-1)" "unprognostic (3.15e-1)" "unprognostic (6.80e-2)" "unprognostic (3.21e-1)" "prognostic favorable (4.34e-4)" "unprognostic (5.64e-3)" "unprognostic (2.26e-2)" "unprognostic (1.72e-1)" "unprognostic (7.11e-3)" 232.4 86.6 49.2 136.0 55.4 84.8 110.0 52.9 67.5 69.5 67.9 110.3 39.7 108.1 81.6 33.3 108.4 85.0 112.5 47.0 52.3 207.3 333.5 154.9 101.1 54.4 54.0 96.4 61.9 151.1 69.5 563.6 57.5 68.2 58.8 32.3 77.6 91.7 71.9 39.8 57.1 125.2 52.4 124.4 71.4 80.1 112.2 33.0 76.1 79.8 49.4 209.8 48.0 59.6 88.1 423.0 32.6 55.3 514.0 2305.0 198.4 267.2 781.8 232.2 300.6 43.0 86.3 0.0 128.9 355.4 754.0 67.5 49.8 86.0 198.4 1.9 37.8 18.1 111.2 105.1 352.6 0.1 51.4 1061.0 138.9 373.7 134.9 186.6 194.9 0.0 162.5 0.7 326.6 115.6 0.5 9.9 67.7 128.6 77.5 21.6 21.5 0.6 158.6 39.0 42.8 50.6 62.1 133.5 312.3 177.9 14.5 97.9 296.9 190.8 104.7 750.6 125.9 18.5 84.1 0.9 692.6 0.2 67.9 0.3 13.5 0.6 0.3 128.1 0.0 0.0 6.6 0.1 7.9 0.1 16.7 1.3 0.5 0.2 195.2 0.3 1.7 10.1 49.2 55.4 52.9 67.5 47.0 52.3 54.4 54.0 57.5 52.4 112.2 59.6 86.1 41.7 52.9 15.3 11.2 37.7 82.1 58.0 15.4 43.8 12.2 33.4 96.8 87.2 46.4 75.4 18.8 1081.6 0.3 16.3 27.4 91.8 5.3 48.1 119.9 110.0 11.5 251.2 18.6 93.4 1012.3 261.7 10.2 27.6 29.7 63.6 580.4 122.6 1105.7 13.5 24.0 8.5 20.3 206.9 105.4 17.4 156.9 537.2 64.0 14.0 16.2 79.5 0.0 17.6 31.7 67.2 5.6 187.3 1.9 34.5 8.0 138.3 67.3 45.4 92.1 176.9 136.3 207.4 60.5 6.8 34.0 1543.6 10.8 30.8 11.7 44.8 CTSS ENSG00000163131 "Cathepsin S" P25774 1 150730079-150765957 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 137.0;lymphoid tissue: 164.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 698.6;Kupffer cells: 2230.8;Macrophages: 1316.2;monocytes: 2312.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 2483.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 81.6;HMC-1: 187.5;U-698: 387.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000460, HPA002988" Supported Approved Vesicles "Intracellular and membrane" NA NA 23000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "CAB000460: , HPA002988: AB_1078409" "unprognostic (7.81e-2)" "unprognostic (9.04e-2)" "unprognostic (3.23e-2)" "unprognostic (3.93e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-2)" "unprognostic (1.11e-1)" "unprognostic (1.23e-1)" "unprognostic (1.59e-1)" "unprognostic (6.00e-3)" "unprognostic (1.46e-1)" "unprognostic (3.89e-1)" "unprognostic (6.24e-2)" "unprognostic (7.50e-2)" "unprognostic (4.14e-2)" "unprognostic (2.13e-1)" "unprognostic (2.47e-3)" 40.0 16.7 4.0 87.8 4.5 137.0 20.3 4.8 7.1 9.4 8.0 83.6 60.2 7.8 5.7 16.5 17.8 29.1 10.6 3.4 5.5 9.3 40.4 88.4 71.7 11.8 8.0 4.9 11.3 2.3 4.7 23.6 11.2 9.1 59.4 3.4 23.9 7.3 4.1 7.1 64.6 16.3 7.7 164.8 42.6 3.8 10.4 20.1 11.5 9.0 38.5 42.9 10.0 16.1 3.7 10.9 0.2 0.3 1.2 1.4 0.7 0.4 8.6 0.9 1.3 1.2 81.6 44.3 5.7 1.2 15.3 2.1 0.2 0.7 0.5 26.9 0.2 29.0 1.1 0.8 0.2 33.6 187.5 2.6 0.1 6.6 1.5 0.5 6.3 0.6 3.4 45.0 2.4 0.3 0.4 22.5 0.2 0.1 0.3 14.9 4.6 49.8 10.7 8.7 0.3 0.4 1.1 2.3 0.8 0.3 0.4 49.8 9.1 6.2 1.3 0.8 1.2 27.8 2.2 387.3 28.5 35.2 2.3 20.9 2483.4 218.0 41.3 1735.3 51.1 139.5 46.6 50.9 571.0 138.8 45.0 40.8 1022.2 41.8 1655.1 106.8 77.4 2577.6 4.0 4.5 4.8 7.1 3.4 5.5 11.8 8.0 11.2 7.7 10.4 16.1 37.6 109.0 158.7 1.6 255.3 17.0 31.3 72.0 4.6 2.3 21.0 8.9 5.3 74.4 143.4 42.3 12.5 3.7 198.0 549.2 0.0 183.6 6.6 126.9 8.6 44.1 42.4 22.5 10.3 177.0 5.7 34.4 71.9 39.0 106.8 9.5 60.3 30.6 698.6 0.0 9.5 205.7 73.2 2230.8 316.4 3.0 5.3 1316.2 56.9 27.2 2312.9 0.5 137.0 0.5 0.9 200.9 466.5 2.2 121.4 20.6 210.8 4.7 488.9 4.9 19.7 5.6 13.3 0.2 0.5 12.4 15.5 6.2 108.9 66.0 237.8 113.3 CTSZ CTSX ENSG00000101160 "Cathepsin Z" Q9UBR2 20 58985686-59008238 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 1078.9;Langerhans cells: 983.5;Macrophages: 652.3;monocytes: 723.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 542.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025114, HPA049876, HPA053504" Supported Supported Vesicles "Intracellular and membrane" NA NA 88000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Vesicles "CAB025114: , HPA049876: AB_2680927, HPA053504: AB_2682172" "unprognostic (7.30e-2)" "unprognostic (3.98e-2)" "unprognostic (4.07e-2)" "unprognostic (1.11e-3)" "unprognostic (8.25e-3)" "unprognostic (1.15e-1)" "unprognostic (4.12e-2)" "unprognostic (6.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (1.33e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (5.72e-5)" "unprognostic (1.96e-1)" "unprognostic (6.92e-2)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" 178.1 117.8 18.9 208.8 21.8 99.8 137.0 20.5 32.0 92.1 59.6 173.8 215.4 87.3 13.4 53.1 88.9 89.4 152.6 15.3 33.9 125.6 356.4 233.3 271.5 31.6 23.5 71.0 89.4 91.8 112.5 118.7 27.9 87.8 77.1 4.1 181.0 66.3 58.7 58.5 226.0 97.9 26.2 234.4 88.2 24.6 47.2 57.1 122.3 54.6 91.3 146.3 69.0 45.4 205.4 139.8 1.1 1.1 114.2 124.2 106.5 291.0 225.4 187.4 152.3 231.6 324.6 96.5 213.9 542.1 0.5 160.1 51.4 257.5 30.2 362.1 13.6 80.3 169.0 0.8 137.3 9.0 331.0 130.9 127.8 83.1 62.4 34.8 281.3 1.1 74.0 48.7 90.0 1.1 1.3 70.6 11.5 43.5 158.2 2.9 0.4 135.7 86.3 25.5 2.7 1.7 222.4 258.4 0.8 19.5 131.9 148.4 420.5 1.4 161.8 209.0 2.0 253.7 172.0 18.2 2.8 207.9 0.4 1.2 1.5 1.6 0.6 1.4 0.4 1.1 0.6 0.4 1.1 1.4 0.7 0.8 1.6 0.5 2.9 1.8 0.3 0.7 18.9 21.8 20.5 32.0 15.3 33.9 31.6 23.5 27.9 26.2 47.2 45.4 132.1 16.0 5.3 5.9 119.8 50.3 64.5 33.8 24.5 6.7 67.4 99.6 21.7 62.9 14.1 71.7 0.0 38.2 104.8 303.6 23.5 176.0 3.5 52.9 47.7 82.2 27.1 63.3 5.3 42.4 104.8 71.5 19.4 71.3 10.8 68.4 62.8 363.0 1078.9 11.8 3.0 56.6 26.4 334.0 983.5 6.0 13.1 652.3 101.4 23.4 723.6 58.6 21.6 2.5 2.5 82.6 217.5 13.9 96.3 50.6 339.8 90.0 18.8 5.0 46.0 67.5 74.5 3.7 4.8 14.5 41.5 41.3 33.4 3.3 99.7 52.7 CTTN EMS1 ENSG00000085733 Cortactin Q14247 11 70398404-70436584 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.2;neutrophil: 2.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.1" "Cell line enhanced" "Detected in many" "A-431: 450.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011235, HPA057242" Supported Supported "Golgi apparatus,Vesicles,Plasma membrane,Cytosol" NA NA 11000000 "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "Golgi apparatus, Vesicles" "CAB011235: , HPA057242: AB_2683379" "unprognostic (6.34e-2)" "unprognostic (2.65e-2)" "unprognostic (2.05e-1)" "unprognostic (3.13e-2)" "unprognostic (5.81e-2)" "prognostic unfavorable (2.19e-6)" "prognostic unfavorable (4.45e-4)" "unprognostic (6.10e-2)" "unprognostic (2.39e-1)" "unprognostic (1.10e-1)" "unprognostic (1.25e-3)" "unprognostic (1.20e-1)" "unprognostic (1.50e-2)" "unprognostic (6.97e-2)" "unprognostic (2.79e-1)" "unprognostic (3.72e-3)" "unprognostic (1.94e-1)" 91.7 142.5 28.3 15.6 30.0 4.9 82.9 29.7 32.3 112.3 28.5 84.9 28.4 117.8 18.7 131.6 85.0 35.1 106.9 27.7 28.2 109.6 66.9 74.8 9.0 33.2 30.8 112.9 79.5 18.1 94.1 23.9 30.9 101.6 23.8 8.4 92.9 27.0 65.7 104.4 70.9 31.8 29.5 53.3 92.2 62.0 30.3 8.7 89.5 14.5 12.7 88.1 101.2 32.5 450.2 97.2 32.0 37.2 53.2 81.9 52.5 93.8 92.5 80.7 63.4 129.5 110.3 17.5 90.6 121.1 86.3 97.3 38.6 98.7 58.7 35.5 39.1 1.7 73.6 61.1 113.9 0.4 22.6 116.6 68.0 89.4 50.2 84.4 68.8 0.5 51.3 3.3 80.9 122.9 0.9 6.4 35.0 163.4 58.6 0.2 39.3 14.3 90.5 143.7 26.3 44.9 68.3 93.2 158.0 57.2 75.8 1.9 86.8 70.8 45.3 111.2 63.6 7.4 5.2 1.0 141.1 0.4 98.9 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 2.1 0.0 0.1 0.4 0.0 6.8 28.3 30.0 29.7 32.3 27.7 28.2 33.2 30.8 30.9 29.5 30.3 32.5 95.3 44.8 51.8 61.7 4.0 151.9 102.8 85.8 46.1 39.4 81.0 57.9 64.1 80.1 95.4 134.3 18.8 83.8 1.6 224.4 64.6 146.5 12.4 86.4 84.8 89.9 74.4 18.9 93.4 221.5 95.6 89.1 76.0 116.1 6.3 117.7 78.9 44.1 10.4 38.7 65.4 123.8 57.0 8.9 34.1 26.1 103.2 38.6 122.7 28.1 5.9 42.5 0.0 40.2 145.8 260.6 177.8 98.9 3.1 153.5 108.4 164.3 89.4 32.5 59.2 61.0 87.5 32.0 47.0 76.7 174.9 106.3 5.4 91.4 111.9 258.1 CUZD1 "ERG-1, UO-44" ENSG00000138161 "CUB and zona pellucida like domains 1" Q86UP6 10 122832158-122846175 "Predicted membrane proteins" "Cell adhesion, Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 1631 "pancreas: 2414.2" "Cell type enriched" "Detected in some" 6 "Exocrine glandular cells: 266.9" "Cancer enriched" "Detected in some" 54 "pancreatic cancer: 32.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-HME1: 1.9;U-937: 1.2" "Not detected" "Not detected" "HPA068479, HPA068660, HPA074117" Enhanced Approved Nucleoli,Vesicles No No "Cluster 25: Pancreas - Digestion" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" Nucleoli Vesicles "HPA068479: AB_2685995, HPA068660: AB_2686015, HPA074117: AB_2686663" "unprognostic (4.68e-2)" "unprognostic (3.48e-2)" "unprognostic (1.53e-2)" "unprognostic (1.52e-5)" "unprognostic (8.08e-2)" "unprognostic (5.20e-3)" "unprognostic (1.16e-4)" "unprognostic (4.19e-2)" "unprognostic (3.03e-2)" "unprognostic (5.15e-2)" "unprognostic (8.46e-2)" "unprognostic (6.64e-3)" "unprognostic (2.75e-3)" "unprognostic (4.48e-1)" "unprognostic (1.38e-1)" "unprognostic (1.56e-1)" "unprognostic (4.83e-4)" 0.4 0.2 0.2 0.2 0.3 0.8 0.4 0.2 0.5 0.6 0.2 0.6 0.5 0.4 0.4 0.5 0.4 0.0 0.4 0.3 0.2 0.9 0.2 0.5 0.2 0.2 0.2 1.0 2414.2 0.0 1.4 0.1 0.4 0.7 0.0 0.4 0.5 0.0 0.1 0.7 0.9 0.0 0.2 1.1 0.4 1.0 0.2 0.3 0.5 0.0 0.0 0.5 0.5 0.3 0.3 0.5 0.1 0.0 0.0 0.3 0.4 0.1 0.1 0.0 0.7 0.0 0.1 0.1 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.9 0.1 0.2 0.3 0.3 0.3 1.0 0.1 0.4 0.3 0.4 0.4 0.0 0.0 0.4 0.0 0.4 0.1 0.4 0.2 0.3 0.0 0.3 0.5 0.4 0.6 0.5 0.0 0.5 0.2 0.0 0.0 0.4 0.8 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.3 0.2 0.5 0.3 0.2 0.2 0.2 0.4 0.2 0.2 0.3 0.2 0.0 0.0 0.0 0.2 0.6 0.2 0.0 0.0 0.7 0.2 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.9 2.8 0.1 0.1 0.1 0.0 0.4 0.0 266.9 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 5.0 0.0 0.1 0.0 0.3 0.3 6.7 0.3 0.1 0.0 0.0 3.7 0.1 0.0 0.0 0.0 43.6 0.1 0.4 0.2 0.1 0.0 0.0 0.1 0.5 0.0 0.4 0.1 0.7 0.2 0.0 0.1 0.0 0.7 0.1 0.2 0.1 CXCL16 "CXCLG16, SR-PSOX, SRPSOX" ENSG00000161921 "C-X-C motif chemokine ligand 16" Q9H2A7 17 4733533-4739928 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Late spermatids: 4051.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 63.3;intermediate monocyte: 107.5;myeloid DC: 38.2;neutrophil: 103.2;non-classical monocyte: 141.6" "Group enriched" "Detected in many" 7 "dendritic cells: 38.2;granulocytes: 103.2;monocytes: 141.6" "Cell line enhanced" "Detected in many" "A-431: 86.5;CACO-2: 63.5;CAPAN-2: 58.4;HaCaT: 97.9;T-47d: 57.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA053253, HPA066315" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 1100000 6800000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 83: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" Vesicles "HPA053253: AB_2682091, HPA066315: AB_2685657" "unprognostic (4.64e-3)" "unprognostic (5.16e-2)" "unprognostic (1.11e-1)" "unprognostic (3.50e-2)" "unprognostic (1.11e-1)" "unprognostic (1.78e-1)" "unprognostic (1.54e-2)" "unprognostic (1.48e-1)" "unprognostic (1.24e-1)" "unprognostic (4.05e-1)" "unprognostic (4.22e-2)" "unprognostic (2.08e-1)" "unprognostic (4.78e-2)" "unprognostic (4.74e-2)" "unprognostic (2.37e-2)" "unprognostic (2.48e-2)" "unprognostic (2.60e-1)" 27.6 18.1 18.7 56.0 19.4 70.4 29.3 20.0 30.7 19.8 20.8 21.9 45.7 11.7 15.3 24.6 24.0 54.0 7.8 17.4 23.0 19.6 52.6 106.0 23.7 32.5 22.7 10.5 20.8 61.8 14.4 31.1 27.9 16.3 25.8 10.2 47.1 14.4 2.6 21.8 39.3 17.6 25.2 43.8 41.2 112.6 28.7 12.5 10.5 3.3 17.9 60.6 14.3 34.2 86.5 12.4 0.4 44.7 0.7 3.1 11.5 1.1 8.9 11.2 15.6 63.5 58.4 0.1 10.0 1.5 8.6 97.9 20.0 14.1 5.3 8.9 14.8 0.4 1.7 29.5 8.5 0.1 15.8 0.7 26.6 5.9 1.3 7.4 3.1 0.9 0.4 0.7 0.8 20.9 0.3 1.8 0.4 42.1 7.2 1.2 0.0 13.2 30.4 15.8 0.4 1.4 17.6 11.3 5.5 2.3 57.4 1.4 0.4 1.5 6.8 2.2 5.3 3.0 3.9 0.1 0.5 2.9 2.4 0.6 63.3 16.7 0.5 107.5 0.7 9.5 1.1 0.8 38.2 13.0 0.8 1.2 103.2 0.6 141.6 16.0 0.1 29.2 18.7 19.4 20.0 30.7 17.4 23.0 32.5 22.7 27.9 25.2 28.7 34.2 9.7 73.7 46.6 1.6 17.4 70.1 130.4 133.4 40.5 2.6 64.8 50.3 0.8 58.6 132.4 40.5 2.1 3.4 11.1 28.1 3.9 151.0 795.4 22.1 4.1 25.4 30.9 2.7 0.1 145.9 2.5 14.2 36.7 32.7 74.1 2.3 132.1 9.0 196.4 3.3 0.3 32.2 44.7 231.6 406.3 4051.5 24.5 270.6 26.6 15.0 556.1 13.2 1.0 5.0 1.2 188.1 44.5 30.1 2.2 277.2 51.3 17.4 62.4 1.3 19.7 3.4 14.4 22.7 11.5 33.7 76.4 2.9 11.7 1.6 23.7 272.7 CXCL5 "ENA-78, SCYB5" ENSG00000163735 "C-X-C motif chemokine ligand 5" P42830 4 73995642-73998677 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lymphoid tissue: 35.9;salivary gland: 50.2" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 64.6;Ductal cells: 94.0;Macrophages: 222.6;Pancreatic endocrine cells: 245.4" "Group enriched" "Detected in many" 4 "pancreatic cancer: 56.2;stomach cancer: 74.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 191.9;EFO-21: 157.0;HSkMC: 111.4;hTEC/SVTERT24-B: 81.6;RPTEC TERT1: 603.6" HPA065474 Approved Approved Vesicles "Secreted to blood" NA NA 1110000 1600000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA065474: AB_2685494" "unprognostic (5.56e-3)" "prognostic unfavorable (3.43e-4)" "unprognostic (1.80e-2)" "unprognostic (1.43e-2)" "unprognostic (2.04e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (1.39e-4)" "unprognostic (1.06e-2)" "unprognostic (3.04e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (2.23e-4)" "unprognostic (7.99e-2)" "prognostic unfavorable (2.45e-5)" "unprognostic (3.72e-1)" "unprognostic (3.07e-1)" "unprognostic (2.72e-2)" "unprognostic (9.30e-2)" 2.1 0.2 1.5 35.9 0.9 1.2 3.2 0.6 8.8 7.7 0.4 0.7 0.8 0.2 0.0 0.1 0.2 4.8 0.6 0.8 2.6 0.2 1.3 10.0 6.3 1.4 2.1 0.0 0.5 0.0 0.1 0.2 3.1 1.3 0.3 0.0 50.2 0.5 0.1 0.0 2.1 0.2 1.1 2.1 8.5 0.4 5.7 0.6 0.0 0.2 0.6 8.4 0.0 0.7 0.1 191.9 0.7 0.0 0.3 6.9 0.0 3.5 2.9 1.5 3.0 0.6 1.6 0.0 157.0 0.1 34.0 0.4 0.0 0.0 17.6 0.2 0.0 0.0 0.0 0.0 15.1 0.0 0.0 111.4 0.0 81.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 603.6 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.5 0.0 1.0 0.0 0.1 0.0 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 2.0 1.5 0.9 0.6 8.8 0.8 2.6 1.4 2.1 3.1 1.1 5.7 0.7 0.2 3.2 0.0 0.0 0.0 0.9 0.7 64.6 0.0 0.0 8.0 4.4 1.2 15.7 33.2 0.0 0.0 0.0 0.1 1.3 0.0 94.0 0.7 0.7 0.1 1.8 0.0 0.0 0.3 1.4 0.1 3.6 15.3 1.2 0.0 0.0 0.7 0.0 0.5 0.0 0.3 0.7 4.1 0.3 30.4 0.3 0.0 222.6 0.0 1.0 2.1 0.0 0.0 0.0 0.1 245.4 0.0 0.0 0.3 3.1 0.0 0.1 4.3 0.0 0.0 0.6 4.0 0.1 0.6 0.0 0.3 0.0 0.3 0.0 1.1 2.0 CXorf38 MGC39350 ENSG00000185753 "Chromosome X open reading frame 38" Q8TB03 X 40626921-40647561 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 61.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050120 Approved Approved Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 57: B-cells - Immune response" "Vesicles, Cytosol" "HPA050120: AB_2681024" "unprognostic (5.40e-2)" "unprognostic (1.03e-1)" "unprognostic (2.91e-1)" "unprognostic (6.98e-2)" "unprognostic (1.37e-1)" "unprognostic (3.15e-1)" "unprognostic (1.48e-3)" "unprognostic (7.59e-2)" "unprognostic (1.46e-1)" "unprognostic (9.40e-2)" "prognostic unfavorable (7.30e-4)" "unprognostic (1.23e-1)" "unprognostic (1.71e-3)" "unprognostic (2.87e-2)" "unprognostic (1.23e-1)" "unprognostic (4.73e-2)" "prognostic favorable (1.44e-8)" 9.0 8.2 5.1 11.5 5.9 10.5 8.2 5.8 5.3 8.0 4.5 7.6 8.3 7.3 4.6 6.1 10.0 6.4 4.8 4.9 5.3 8.1 8.0 10.2 16.1 6.2 5.6 9.5 6.0 9.5 4.8 6.8 6.3 6.3 7.7 5.7 6.5 6.1 5.0 7.9 9.7 5.8 5.8 14.4 6.6 2.1 5.9 13.2 11.1 4.1 13.4 7.2 7.0 7.0 11.3 5.9 6.2 4.9 6.5 10.8 3.3 7.5 10.5 9.1 9.1 7.7 15.8 18.5 6.4 11.2 15.2 7.4 7.6 12.5 8.3 25.7 11.4 12.5 7.1 4.6 10.8 22.0 18.6 9.6 9.0 12.7 12.5 8.7 10.4 15.8 5.3 13.7 17.0 10.5 15.4 16.7 5.6 8.2 12.8 12.7 13.2 14.4 10.7 17.0 7.0 9.6 15.1 7.5 8.9 11.6 11.4 10.1 13.0 11.9 6.8 8.7 6.5 14.7 5.5 7.9 15.4 11.4 8.0 9.3 16.0 22.1 9.2 15.8 9.7 6.9 8.7 7.4 14.2 9.6 7.6 7.8 19.7 7.3 25.1 5.9 10.9 10.3 5.1 5.9 5.8 5.3 4.9 5.3 6.2 5.6 6.3 5.8 5.9 7.0 19.8 9.6 9.1 10.1 26.9 3.6 11.3 6.3 10.8 12.6 10.5 8.0 6.4 18.6 7.6 16.5 18.8 9.2 48.3 15.1 7.9 27.7 1.0 25.2 15.0 14.0 7.3 6.3 11.9 30.1 9.7 8.9 9.7 21.6 17.1 16.5 10.4 10.8 36.6 15.2 13.1 12.7 8.2 30.7 9.8 1.3 9.6 29.5 3.6 8.4 61.9 10.2 41.2 12.1 17.8 40.5 17.2 5.3 16.4 14.7 15.8 14.4 7.8 7.6 6.6 13.5 9.2 6.5 7.4 9.7 5.4 8.2 31.2 20.6 13.3 28.3 CYB561A3 CYBASC3 ENSG00000162144 "Cytochrome b561 family member A3" Q8NBI2 11 61348754-61362283 "Predicted membrane proteins" "Electron transport, Transport" "Oxidoreductase, Translocase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 251.4" "Cell type enhanced" "Detected in all" "dendritic cells: 145.1;Melanocytes: 320.2;Theca cells: 128.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "memory B-cell: 314.5;naive B-cell: 386.6;plasmacytoid DC: 841.4" "Group enriched" "Detected in all" 9 "B-cells: 386.6;dendritic cells: 841.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045674, HPA052548" Approved Approved Nucleoli,Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles Nucleoli "HPA045674: , HPA052548: AB_2681866" "unprognostic (2.61e-1)" "unprognostic (8.78e-2)" "unprognostic (4.16e-1)" "unprognostic (3.62e-2)" "unprognostic (1.37e-1)" "unprognostic (9.41e-3)" "unprognostic (7.41e-3)" "unprognostic (2.48e-1)" "unprognostic (1.90e-1)" "unprognostic (2.12e-1)" "unprognostic (2.22e-2)" "unprognostic (3.73e-1)" "unprognostic (2.53e-1)" "unprognostic (2.83e-1)" "unprognostic (3.71e-2)" "unprognostic (1.19e-1)" "unprognostic (1.80e-3)" 19.5 251.4 10.2 32.6 11.5 26.0 17.3 10.5 10.7 17.1 17.4 33.3 19.2 24.1 18.7 19.6 30.4 27.5 12.3 11.0 10.1 15.3 31.0 21.3 70.3 13.0 13.7 27.1 24.4 21.5 13.8 17.3 12.6 20.9 27.8 11.4 21.8 19.8 26.1 76.0 27.8 18.8 12.3 49.7 20.8 13.6 12.1 28.1 18.5 17.7 70.4 22.9 16.2 14.0 50.2 80.6 13.4 40.6 67.8 41.9 11.3 26.0 37.3 29.8 28.9 22.6 54.3 98.1 42.1 46.2 24.0 67.5 13.6 72.2 20.1 64.5 28.5 18.3 53.6 16.5 32.0 24.9 42.3 63.4 95.7 65.3 30.0 25.0 44.1 46.1 55.5 57.3 51.2 53.3 45.7 11.4 24.5 44.7 51.9 52.2 14.0 72.6 35.2 48.1 16.2 26.1 54.7 71.5 60.5 9.6 58.6 29.3 31.7 34.2 17.8 34.2 35.6 34.3 49.9 56.8 50.6 44.2 46.4 19.4 66.4 35.5 31.0 53.8 28.6 314.5 22.1 29.2 63.5 386.6 23.5 24.6 21.8 31.5 64.0 841.4 23.6 84.8 10.2 11.5 10.5 10.7 11.0 10.1 13.0 13.7 12.6 12.3 12.1 14.0 13.0 6.4 22.8 6.8 96.2 28.3 18.3 86.6 19.9 15.9 19.6 18.7 1.9 10.0 30.0 12.9 31.3 49.9 145.1 53.6 11.7 26.2 53.6 15.4 12.0 13.5 19.2 14.1 4.3 38.8 39.5 16.4 21.4 7.5 8.8 13.0 15.4 21.0 51.4 18.5 4.1 28.9 22.4 23.8 21.2 14.2 20.8 47.9 320.2 8.4 57.1 23.7 28.8 5.5 7.2 26.6 48.9 20.7 10.5 15.9 55.6 13.7 72.0 56.2 13.1 14.8 15.8 7.2 11.5 18.4 24.0 39.5 18.7 128.9 30.7 16.2 CYB5A CYB5 ENSG00000166347 "Cytochrome b5 type A" P00167 18 74250846-74291973 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 889.6;liver: 2472.0" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 1371.0;Distal tubular cells: 2156.1;Hepatocytes: 3376.3;Proximal enterocytes: 1856.4;Proximal tubular cells: 3630.6" "Cancer enhanced" "Detected in all" "liver cancer: 43.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 1117.0;RT4: 513.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006333, HPA047548, HPA058547" Enhanced Enhanced Vesicles,Cytosol No No 1400000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "CAB006333: , HPA047548: AB_2680084, HPA058547: AB_2683750" "unprognostic (1.88e-1)" "unprognostic (1.28e-1)" "prognostic favorable (5.23e-4)" "unprognostic (1.08e-2)" "unprognostic (1.41e-1)" "unprognostic (9.14e-2)" "prognostic favorable (4.15e-4)" "unprognostic (7.79e-3)" "unprognostic (1.11e-1)" "unprognostic (3.33e-2)" "unprognostic (2.68e-2)" "unprognostic (1.65e-2)" "unprognostic (1.17e-1)" "unprognostic (1.95e-1)" "unprognostic (1.75e-1)" "unprognostic (4.64e-2)" "unprognostic (8.54e-2)" 309.5 109.6 38.4 31.2 39.7 25.3 253.5 42.2 45.2 86.0 37.6 146.5 438.2 44.9 176.2 78.1 81.9 301.2 84.8 37.5 38.8 889.6 2472.0 356.6 43.7 43.1 39.7 223.9 461.3 236.0 58.5 81.8 41.9 95.9 103.4 10.3 59.1 122.8 41.4 118.4 381.7 46.7 40.8 75.6 194.8 57.9 40.0 51.6 42.5 42.1 35.2 155.5 68.3 43.5 78.8 130.8 67.4 0.6 1117.0 198.2 89.5 52.6 113.8 111.0 163.8 156.2 82.7 95.6 36.7 97.6 54.4 170.6 0.1 73.1 86.9 179.8 91.7 34.9 65.6 418.1 174.6 67.3 44.1 334.1 57.4 63.0 32.3 66.0 63.6 85.8 58.6 35.0 93.7 140.9 38.3 80.5 30.4 110.0 86.8 93.6 21.9 2.3 111.9 513.2 190.4 79.7 51.4 137.1 65.8 56.6 271.5 63.7 57.9 0.6 85.8 26.6 68.1 24.6 109.2 30.3 67.0 19.2 64.3 4.1 29.5 7.5 51.3 36.3 116.2 93.7 55.6 60.2 53.7 112.7 54.5 68.6 3.7 36.3 45.7 47.8 48.8 43.2 38.4 39.7 42.2 45.2 37.5 38.8 43.1 39.7 41.9 40.8 40.0 43.5 169.7 637.8 1371.0 11.4 76.0 98.0 82.1 368.6 50.7 9.9 345.8 213.2 90.7 836.4 1053.2 842.4 4.2 229.3 29.4 197.0 2156.1 239.4 7.5 163.1 76.6 119.9 164.2 180.0 13.1 504.6 169.8 141.4 208.9 345.6 39.9 55.0 177.4 3376.3 97.4 8.4 12.6 236.5 457.7 128.6 72.9 26.7 158.1 60.8 90.7 10.3 224.1 39.2 32.0 14.1 22.7 266.7 358.9 149.7 33.4 142.0 1856.4 3630.6 619.5 14.0 52.6 49.6 85.0 15.3 42.0 141.2 223.9 44.5 52.6 1123.6 329.9 220.7 CYP17A1 "CPT7, CYP17, P450C17, S17AH" ENSG00000148795 "Cytochrome P450 family 17 subfamily A member 1" P05093 10 102830531-102837472 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Steroidogenesis "Lyase, Monooxygenase, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 84 "adrenal gland: 8229.5" "Cell type enriched" "Detected in some" 17 "Theca cells: 1871.0" "Cancer enriched" "Detected in many" 5 "liver cancer: 22.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 3.0;SCLC-21H: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA048533 Enhanced Approved Vesicles "Intracellular and membrane" NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "HPA048533: AB_2680432" "unprognostic (1.07e-2)" "unprognostic (8.84e-2)" "unprognostic (3.01e-2)" "unprognostic (9.08e-2)" "unprognostic (1.91e-1)" "unprognostic (6.29e-2)" "unprognostic (2.92e-3)" "unprognostic (2.39e-4)" "unprognostic (8.26e-2)" "unprognostic (2.35e-1)" "unprognostic (5.92e-3)" "unprognostic (1.13e-1)" "prognostic favorable (5.43e-7)" "unprognostic (1.07e-1)" "unprognostic (5.56e-2)" "unprognostic (1.66e-2)" "unprognostic (2.94e-4)" 0.4 8229.5 0.0 2.1 0.0 0.0 0.4 0.1 0.1 1.1 0.0 0.5 0.0 0.8 0.1 0.9 1.0 0.4 1.0 0.0 0.0 52.9 6.7 1.4 0.0 0.0 0.1 16.6 1.7 10.5 0.7 0.0 0.0 0.7 0.0 0.2 3.4 0.0 1.0 0.7 0.6 0.0 0.0 0.9 1.3 98.3 0.0 0.0 2.9 0.0 0.0 0.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 2.2 0.1 0.4 0.1 0.0 0.5 0.0 0.1 0.7 0.0 0.0 1.8 0.0 0.4 0.1 0.1 21.5 0.0 41.6 0.1 0.0 0.7 0.0 2.7 0.1 0.2 0.0 1.3 0.0 0.1 0.0 0.1 0.4 6.1 0.1 1.7 0.1 0.0 0.0 0.6 0.7 10.6 1.8 0.9 0.0 0.0 0.1 0.2 3.1 0.5 0.1 0.7 0.0 0.0 0.0 0.3 0.0 104.3 0.0 1.2 0.0 1.2 0.6 0.3 0.1 0.0 0.0 0.3 0.4 1871.0 0.0 0.1 CYP27C1 FLJ16008 ENSG00000186684 "Cytochrome P450 family 27 subfamily C member 1" Q4G0S4 2 127183832-127220313 "Enzymes, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 4.1;skin 1: 5.1" "Cell type enhanced" "Detected in some" "Club cells: 5.4;Collecting duct cells: 3.7;Endometrial stromal cells: 5.8;Leydig cells: 7.5;Pancreatic endocrine cells: 7.6;Suprabasal keratinocytes: 7.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 7.6;HDLM-2: 11.8;hTERT-RPE1: 12.5;TIME: 11.6;U-138 MG: 10.9;U-251 MG: 7.9" "HPA062460, HPA068731" Enhanced Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA062460: AB_2732683, HPA068731: AB_2686023" "unprognostic (1.90e-1)" "unprognostic (4.07e-2)" "unprognostic (1.15e-1)" "unprognostic (1.38e-2)" "unprognostic (3.03e-1)" "unprognostic (7.75e-3)" "unprognostic (3.48e-1)" "unprognostic (2.31e-3)" "unprognostic (4.38e-2)" "unprognostic (3.15e-1)" "unprognostic (1.81e-3)" "unprognostic (1.11e-1)" "unprognostic (6.29e-4)" "unprognostic (3.49e-4)" "unprognostic (1.83e-1)" "unprognostic (4.27e-2)" "unprognostic (8.64e-2)" 0.6 0.5 0.8 0.4 0.2 0.3 0.3 0.8 0.7 4.1 0.6 1.2 0.3 0.6 0.4 1.6 0.6 0.7 0.9 0.5 1.0 0.2 0.2 0.2 0.3 0.6 2.4 0.2 0.2 0.0 0.1 0.1 0.4 0.9 0.3 0.1 0.3 0.7 0.4 5.1 0.6 0.2 0.3 0.2 0.3 0.3 2.7 0.0 0.1 0.1 0.8 1.8 2.5 0.8 1.3 3.4 1.9 0.1 0.1 0.0 0.1 0.4 3.2 1.8 0.8 0.1 2.8 0.1 0.1 2.0 1.3 7.6 2.7 1.4 0.6 11.8 1.4 0.0 2.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 1.1 12.5 0.4 0.3 0.0 0.2 2.1 0.2 0.3 0.1 4.0 0.0 1.0 0.1 0.2 0.0 5.9 1.0 0.1 0.7 4.9 0.0 0.0 1.5 0.1 0.2 11.6 10.9 2.0 5.3 7.9 0.1 0.1 0.0 0.1 0.1 0.9 0.5 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.2 0.4 0.2 0.1 0.1 0.1 0.0 0.8 0.2 0.8 0.7 0.5 1.0 0.6 2.4 0.4 0.3 2.7 0.8 0.2 0.0 0.6 0.0 0.2 1.8 1.2 2.1 0.0 0.0 1.5 0.3 0.5 0.0 5.4 3.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 5.8 0.5 0.0 0.0 0.6 0.2 0.0 2.4 0.0 0.5 0.0 0.2 0.4 0.1 0.0 0.0 0.7 0.0 2.0 0.0 1.9 0.1 7.5 0.2 0.0 0.0 0.1 0.0 0.0 0.5 0.2 7.6 0.0 0.4 0.0 1.6 0.0 0.0 0.2 0.0 0.0 1.5 1.0 0.1 0.7 0.0 7.2 0.0 0.2 0.0 0.0 2.9 CYP2C18 "CPCI, CYP2C, CYP2C17, P450IIC17" ENSG00000108242 "Cytochrome P450 family 2 subfamily C member 18" P33260 10 94683729-94736190 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 102.8;liver: 197.0;stomach 1: 67.2" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 68.8;Hepatocytes: 124.0;Proximal enterocytes: 62.5;Squamous epithelial cells: 22.8" "Cancer enhanced" "Detected in many" "liver cancer: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.2;OE19: 1.9" "Not detected" "Not detected" HPA074424 Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "HPA074424: " "unprognostic (2.40e-1)" "unprognostic (1.75e-2)" "unprognostic (2.69e-1)" "unprognostic (1.10e-2)" "unprognostic (1.32e-2)" "unprognostic (2.57e-1)" "unprognostic (2.71e-1)" "unprognostic (9.78e-2)" "unprognostic (2.28e-1)" "unprognostic (4.22e-3)" "unprognostic (1.62e-3)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (6.81e-3)" 0.3 0.0 0.0 1.6 0.1 0.0 0.3 0.2 0.1 5.3 0.0 5.9 102.8 0.1 0.0 30.9 0.0 16.3 0.0 0.1 0.0 0.3 197.0 0.8 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 2.5 0.0 5.4 0.0 0.0 4.4 83.1 0.1 0.1 0.0 67.2 0.1 0.1 0.3 0.0 0.0 7.1 0.2 9.5 0.2 0.0 0.1 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.9 0.0 0.0 0.0 0.4 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.1 0.2 0.0 0.0 3.3 0.0 0.3 0.1 0.0 1.6 0.0 0.0 0.0 0.1 0.1 17.2 3.2 0.0 0.0 0.1 0.0 6.7 0.0 1.5 0.0 0.6 0.1 0.0 0.0 2.7 0.5 6.9 0.2 0.1 68.8 1.3 0.0 0.0 1.8 124.0 0.0 0.0 0.8 2.1 2.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 9.1 3.9 0.0 0.3 0.0 62.5 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.3 22.8 1.7 1.5 0.1 0.1 5.7 0.0 CYP2C19 "CPCJ, CYP2C, P450IIC19" ENSG00000165841 "Cytochrome P450 family 2 subfamily C member 19" P33261 10 94762681-94855547 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 190.2" "Group enriched" "Detected in some" 11 "Gastric mucus-secreting cells: 3.1;Hepatocytes: 9.5;Proximal enterocytes: 8.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015066, HPA074424" Supported Uncertain Vesicles "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA015066: AB_1847433, HPA074424: " "unprognostic (3.15e-2)" "unprognostic (2.13e-1)" "unprognostic (2.48e-1)" "unprognostic (1.83e-2)" "unprognostic (1.53e-1)" 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.3 0.2 0.2 0.1 0.2 32.4 0.0 0.1 1.6 0.0 1.7 0.0 0.1 0.0 0.0 190.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.6 13.9 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.3 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 3.1 0.0 0.0 0.0 0.4 9.5 0.0 0.0 0.6 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 CYP2C8 CPC8 ENSG00000138115 "Cytochrome P450 family 2 subfamily C member 8" P10632 10 95036772-95069497 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 359 "liver: 2156.6" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 1834.2" "Cancer enriched" "Detected in some" 82 "liver cancer: 102.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA013547, HPA013970, HPA015066, HPA074424" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "HPA013547: AB_1847435, HPA013970: AB_1847434, HPA015066: AB_1847433, HPA074424: " "unprognostic (3.33e-2)" "unprognostic (1.38e-1)" "unprognostic (1.53e-1)" "unprognostic (1.55e-1)" "unprognostic (4.41e-2)" "unprognostic (1.09e-2)" "unprognostic (1.80e-3)" "unprognostic (4.29e-2)" "unprognostic (1.03e-1)" "unprognostic (3.38e-1)" "prognostic favorable (9.82e-4)" "unprognostic (2.85e-1)" "unprognostic (1.44e-3)" "unprognostic (2.63e-1)" "unprognostic (7.88e-2)" "unprognostic (1.39e-1)" "unprognostic (4.05e-4)" 0.3 1.8 1.7 0.0 1.9 0.2 0.3 1.4 2.1 0.3 1.4 0.4 0.2 0.1 0.3 0.1 1.1 4.6 0.3 1.8 2.2 1.4 2156.6 0.4 0.1 1.7 2.2 0.1 1.7 0.5 3.1 0.1 1.8 0.6 0.0 3.1 0.2 0.3 0.2 0.1 1.1 0.0 1.4 1.0 6.0 4.0 2.1 0.2 0.9 0.0 0.1 0.2 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.9 1.4 2.1 1.8 2.2 1.7 2.2 1.8 1.4 2.1 1.8 0.0 0.0 0.0 1.6 8.9 0.0 0.1 0.0 0.0 1.1 0.1 0.0 0.2 147.3 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 7.3 0.9 0.1 2.0 1.8 57.5 4.5 0.2 0.0 0.1 0.0 0.2 0.0 0.6 52.8 1834.2 0.0 5.0 3.7 0.1 0.0 70.9 0.0 7.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 1.2 0.5 1.2 0.0 0.0 0.1 1.0 0.8 0.9 1.7 0.0 0.0 0.3 2.1 0.6 0.0 0.0 0.0 3.3 0.0 0.2 0.2 CYP2C9 "CYP2C10, P450IIC9" ENSG00000138109 "Cytochrome P450 family 2 subfamily C member 9" P11712 10 94938658-94990091 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "liver: 1719.9" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 1704.9" "Cancer enriched" "Detected in some" 41 "liver cancer: 118.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015066, CAB016123, HPA074424" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "CAB016123: AB_629363, HPA015066: AB_1847433, HPA074424: " "unprognostic (3.37e-1)" "unprognostic (5.68e-2)" "unprognostic (9.67e-2)" "unprognostic (4.16e-2)" "unprognostic (1.83e-2)" "prognostic favorable (2.83e-6)" "unprognostic (2.37e-1)" "unprognostic (2.05e-2)" "unprognostic (4.93e-2)" "unprognostic (1.26e-4)" "unprognostic (7.55e-2)" "unprognostic (1.12e-1)" "unprognostic (2.45e-2)" "unprognostic (1.24e-2)" 0.2 0.0 0.0 0.4 0.0 0.2 0.1 0.1 0.0 1.2 0.0 2.7 87.8 0.0 0.0 7.7 0.0 7.9 0.0 0.0 0.0 4.3 1719.9 0.2 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 1.0 0.0 0.0 2.3 46.2 0.1 0.0 0.5 18.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 18.6 0.2 1.8 0.0 0.0 0.0 1.5 0.0 7.6 0.0 0.8 0.7 1.1 0.0 16.0 0.0 0.7 0.0 0.2 44.4 7.4 0.0 0.0 26.7 1704.9 0.0 0.0 0.1 1.4 0.0 34.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 2.6 0.0 0.1 0.0 65.3 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.1 1.9 0.0 2.7 0.0 CYP2U1 "SPG49, SPG56" ENSG00000155016 "Cytochrome P450 family 2 subfamily U member 1" Q7Z449 4 107931549-107953461 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lymphoid tissue: 84.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 30.2;Inhibitory neurons: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041622, HPA046754, HPA064827" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA041622: AB_2677583, HPA046754: AB_2679787, HPA064827: AB_2685362" "unprognostic (3.54e-1)" "unprognostic (2.45e-1)" "unprognostic (3.08e-1)" "unprognostic (2.84e-1)" "unprognostic (5.16e-2)" "unprognostic (1.08e-1)" "unprognostic (1.36e-2)" "unprognostic (1.20e-3)" "unprognostic (3.19e-1)" "unprognostic (8.97e-3)" "unprognostic (5.41e-3)" "unprognostic (3.02e-1)" "prognostic favorable (2.75e-5)" "prognostic unfavorable (6.97e-4)" "unprognostic (1.19e-1)" "unprognostic (1.17e-2)" "unprognostic (1.11e-1)" 7.7 6.4 6.6 4.0 8.3 0.5 4.5 7.6 7.3 5.1 10.1 5.8 3.4 6.6 3.6 3.5 7.8 5.6 7.7 6.5 8.7 5.3 5.9 5.7 6.3 9.0 7.9 9.5 2.3 10.7 4.7 2.4 8.2 9.9 3.9 5.8 3.4 8.7 3.6 2.7 4.7 10.2 8.1 7.6 3.2 3.0 8.0 84.9 3.6 7.2 4.7 4.7 3.8 9.5 4.0 1.9 5.2 9.5 28.6 13.4 0.8 16.8 25.3 10.2 15.7 0.1 2.5 10.8 1.1 10.1 7.8 0.2 8.1 6.4 15.4 3.0 2.5 2.3 3.5 0.5 11.3 3.2 0.0 15.3 5.3 4.7 3.2 20.8 4.0 12.0 0.1 5.0 8.4 2.9 11.8 0.0 5.4 0.4 4.7 6.5 6.3 0.1 3.3 6.7 10.0 7.6 4.2 7.3 18.6 4.3 3.6 1.5 10.6 6.5 0.8 9.3 6.9 21.1 21.2 3.4 5.5 0.0 7.4 0.0 0.1 0.3 0.4 0.5 0.3 0.8 0.3 0.4 0.9 1.1 0.7 0.5 0.0 0.7 2.8 1.1 0.0 0.2 6.6 8.3 7.6 7.3 6.5 8.7 9.0 7.9 8.2 8.1 8.0 9.5 5.5 3.2 3.9 18.6 12.9 1.1 4.6 2.2 15.4 4.1 2.8 5.8 6.2 1.5 2.4 9.2 4.2 0.4 10.1 1.4 0.0 0.9 13.2 6.9 6.3 5.8 3.0 1.7 30.2 2.0 0.3 12.6 3.1 6.2 4.5 2.5 8.6 7.3 2.3 1.7 34.3 1.2 0.0 6.2 3.3 9.5 17.7 4.7 19.6 5.6 3.7 9.5 1.0 20.1 12.1 0.4 0.1 17.7 4.2 1.5 9.9 3.0 8.6 3.1 0.0 20.0 8.1 1.0 4.2 2.0 1.4 0.3 3.6 5.1 3.1 0.8 CYP3A4 CYP3A3 ENSG00000160868 "Cytochrome P450 family 3 subfamily A member 4" P08684 7 99756960-99784248 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 3796.2" "Group enriched" "Detected in some" 40 "Hepatocytes: 2612.9;Proximal enterocytes: 1685.2" "Cancer enriched" "Detected in some" 240 "liver cancer: 351.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.0;NB-4: 2.2;RPMI-8226: 3.4;SCLC-21H: 1.3;SH-SY5Y: 2.0" "Low region specificity" "Detected in all" "CAB033671, HPA072245, HPA075539" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 24: NB-4 - Immune response" "Cluster 2: Hepatocytes - Metabolism" Cytosol Vesicles "CAB033671: AB_782375, HPA072245: , HPA075539: " "unprognostic (4.55e-2)" "unprognostic (8.95e-2)" "unprognostic (8.08e-2)" "unprognostic (1.63e-1)" "unprognostic (5.89e-2)" "unprognostic (5.37e-2)" "unprognostic (7.07e-3)" "unprognostic (9.09e-2)" "unprognostic (8.27e-3)" "unprognostic (4.92e-2)" "unprognostic (3.78e-2)" "unprognostic (6.42e-2)" "unprognostic (1.89e-8)" "unprognostic (2.59e-1)" "unprognostic (1.75e-2)" "unprognostic (9.79e-2)" "unprognostic (6.82e-2)" 0.3 3.8 0.1 1.1 0.3 0.0 0.3 0.0 0.8 0.1 0.0 4.6 797.6 0.6 0.2 0.4 0.1 0.6 0.1 0.1 0.0 4.9 3796.2 0.1 0.9 0.0 0.0 0.1 43.4 0.0 1.0 0.0 0.0 0.2 2.2 0.4 0.3 0.0 2.4 1.9 853.0 0.0 0.0 0.1 1.1 1.0 0.1 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.8 0.1 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 2.2 0.2 0.0 0.0 0.0 0.8 3.4 0.0 0.1 1.3 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.3 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 2.2 0.4 0.8 0.2 0.0 0.0 0.0 0.0 0.4 32.9 0.0 0.0 0.0 0.3 0.0 5.6 0.0 0.1 0.4 0.0 0.0 1.4 0.0 26.7 0.6 0.9 0.0 0.0 0.0 0.1 0.0 0.0 30.0 2612.9 0.0 0.0 0.6 29.6 2.0 52.8 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.2 0.1 38.9 0.0 0.0 0.6 1685.2 3.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.9 0.1 2.3 0.5 16.1 1.1 CYP3A43 ENSG00000021461 "Cytochrome P450 family 3 subfamily A member 43" Q9HB55 7 99828013-99866102 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 44.7" "Cell type enhanced" "Detected in some" "Astrocytes: 4.6;Early spermatids: 7.5;Excitatory neurons: 3.9;granulocytes: 2.5;Hepatocytes: 6.4;Late spermatids: 3.3;Spermatocytes: 2.4" "Cancer enriched" "Detected in single" 18 "liver cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA066463, HPA072245, HPA075539" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 15: Hepatocytes - Hemostasis" Cytosol Vesicles "HPA066463: AB_2685670, HPA072245: , HPA075539: " "unprognostic (1.20e-3)" "unprognostic (4.74e-2)" "unprognostic (3.64e-3)" "unprognostic (7.24e-2)" "unprognostic (2.52e-1)" "prognostic favorable (3.41e-4)" "unprognostic (1.68e-2)" "unprognostic (1.44e-1)" "unprognostic (2.38e-1)" "unprognostic (1.12e-1)" "unprognostic (6.45e-2)" "unprognostic (1.23e-2)" "unprognostic (6.46e-2)" "unprognostic (5.90e-2)" "unprognostic (3.10e-1)" "unprognostic (6.37e-4)" 0.1 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.8 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.2 44.7 0.1 0.1 0.0 0.0 0.1 5.7 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.2 0.1 0.3 0.2 0.1 0.2 0.0 0.1 0.1 0.8 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.0 0.1 0.1 0.0 0.3 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 4.6 0.0 0.3 0.4 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.2 0.0 0.0 3.9 0.0 0.0 0.3 0.0 0.0 2.5 0.0 0.0 6.4 0.1 1.7 1.9 0.0 0.0 0.6 1.9 3.3 0.0 0.2 0.0 1.0 0.0 0.2 0.0 0.5 1.7 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.7 0.1 2.4 0.3 0.0 0.3 0.0 0.4 0.0 0.0 0.2 CYP3A5 "CP35, P450PCN3, PCN3" ENSG00000106258 "Cytochrome P450 family 3 subfamily A member 5" P20815 7 99648194-99679998 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 177.7;liver: 276.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 377.4;Distal enterocytes: 382.7;Gastric mucus-secreting cells: 506.6;Hepatocytes: 454.5;Paneth cells: 451.6;Proximal enterocytes: 1074.6;Urothelial cells: 380.4" "Cancer enhanced" "Detected in many" "liver cancer: 38.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 9.7;Hep G2: 7.9;OE19: 28.3" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol Vesicles "HPA072245: , HPA075539: " "unprognostic (2.13e-1)" "unprognostic (4.36e-2)" "unprognostic (4.04e-2)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "unprognostic (2.73e-1)" "prognostic favorable (3.72e-5)" "unprognostic (1.37e-3)" "unprognostic (1.21e-2)" "unprognostic (7.29e-3)" "unprognostic (3.85e-1)" "unprognostic (4.05e-2)" "unprognostic (1.46e-1)" "unprognostic (1.00e-1)" "unprognostic (1.93e-1)" "unprognostic (2.39e-4)" "unprognostic (6.58e-3)" 3.3 14.4 0.1 3.8 0.4 0.6 6.5 0.8 0.9 5.1 0.4 28.4 127.3 3.1 3.0 22.1 3.1 32.7 1.0 0.3 0.0 10.6 276.1 9.2 1.4 0.6 0.0 0.8 47.0 0.0 0.9 0.4 0.4 21.6 21.0 0.7 2.9 5.7 0.9 20.5 177.7 1.1 0.0 0.8 86.5 0.4 0.0 2.1 1.0 0.0 3.2 10.4 13.1 0.5 1.6 3.3 1.6 1.9 0.4 0.6 0.5 1.5 0.0 0.0 0.0 9.7 7.4 1.0 1.5 0.0 1.2 1.2 0.0 0.0 0.0 1.8 1.2 1.2 0.7 7.9 0.1 2.0 0.6 0.0 2.1 0.0 0.0 1.4 0.0 0.9 3.3 2.0 0.0 0.3 2.6 3.8 0.4 28.3 0.8 0.6 1.6 2.2 0.4 1.5 1.2 1.7 0.9 0.8 3.2 1.6 0.5 0.7 1.2 1.8 1.6 1.6 1.2 1.0 2.6 1.7 1.6 2.6 1.5 0.4 0.3 0.4 0.4 0.3 0.9 0.2 0.6 0.6 0.2 0.1 0.4 0.5 0.5 0.4 0.2 0.3 0.5 0.2 0.1 0.4 0.8 0.9 0.3 0.0 0.6 0.0 0.4 0.0 0.0 0.5 0.9 12.8 14.8 1.3 4.8 46.1 112.7 31.0 59.7 13.7 1.1 0.4 1.3 377.4 27.3 3.7 12.5 1.7 1.7 382.7 0.0 63.4 2.0 3.1 2.2 6.3 54.6 21.7 8.6 50.7 1.2 8.5 506.6 10.3 10.1 1.8 8.2 454.5 0.6 8.4 11.0 140.5 6.1 9.5 4.5 0.5 2.5 4.1 3.6 2.8 4.9 4.0 10.3 7.1 6.5 80.1 451.6 2.6 6.4 156.3 1074.6 10.8 12.1 21.6 0.0 2.5 3.4 15.1 6.4 107.3 59.0 1.5 7.5 3.1 139.8 380.4 CYP3A7 "CP37, P450-HFLA" ENSG00000160870 "Cytochrome P450 family 3 subfamily A member 7" P24462 7 99705036-99735196 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "liver: 304.9" "Group enriched" "Detected in some" 17 "Cholangiocytes: 85.8;Hepatocytes: 60.5" "Cancer enriched" "Detected in some" 43 "liver cancer: 38.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.3;Hep G2: 2.5;HHSteC: 1.4" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Cytosol Vesicles "HPA072245: , HPA075539: " "unprognostic (8.10e-3)" "unprognostic (1.45e-1)" "unprognostic (3.12e-1)" "unprognostic (5.47e-2)" "unprognostic (1.73e-1)" "unprognostic (1.44e-1)" "unprognostic (4.41e-2)" "unprognostic (1.50e-1)" "unprognostic (1.34e-2)" "unprognostic (8.28e-2)" "unprognostic (8.18e-2)" "unprognostic (1.97e-1)" "unprognostic (1.06e-11)" "unprognostic (2.02e-2)" "unprognostic (5.87e-2)" "unprognostic (2.97e-1)" "unprognostic (1.34e-3)" 0.2 0.9 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 0.0 0.2 0.5 0.3 0.3 0.1 0.0 6.5 0.0 0.0 0.1 8.5 304.9 2.4 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.1 0.1 0.0 0.2 1.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.6 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.9 0.0 0.0 0.0 0.0 0.1 85.8 0.3 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 3.3 60.5 0.1 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 3.8 4.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 1.3 0.0 0.2 CYP3A7-CYP3A51P ENSG00000282301 "CYP3A7-CYP3A51P readthrough" 7 99684957-99735102 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "liver: 12.7" "Group enriched" "Detected in some" 10 "Cholangiocytes: 4.3;Hepatocytes: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA072245, HPA075539" Approved Vesicles,Cytosol NA NA "Cluster 85: Liver - Metabolism" "Cluster 15: Hepatocytes - Hemostasis" Cytosol Vesicles "HPA072245: , HPA075539: " 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 1.1 0.1 0.0 0.0 1.5 12.7 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.4 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.2 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.2 0.2 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CYP4B1 ENSG00000142973 "Cytochrome P450 family 4 subfamily B member 1" P13584 1 46757838-46819413 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 242.2" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 1227.5;Club cells: 405.1;Respiratory ciliated cells: 763.9" "Cancer enhanced" "Detected in many" "urothelial cancer: 56.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "RT4: 286.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA004331 Approved Supported Vesicles NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA004331: AB_1078616" "unprognostic (2.29e-2)" "prognostic favorable (5.99e-4)" "unprognostic (7.01e-2)" "unprognostic (1.11e-1)" "unprognostic (2.28e-1)" "unprognostic (8.31e-2)" "unprognostic (1.16e-2)" "unprognostic (1.98e-2)" "unprognostic (2.65e-1)" "unprognostic (2.59e-1)" "unprognostic (6.12e-2)" "unprognostic (5.46e-2)" "unprognostic (7.33e-2)" "unprognostic (1.80e-1)" "unprognostic (1.15e-1)" "unprognostic (1.22e-3)" "unprognostic (6.69e-3)" 81.8 4.9 0.3 0.0 0.3 0.0 62.0 0.2 0.6 13.4 1.2 14.6 1.3 9.5 1.7 44.0 48.0 0.5 40.2 0.2 0.3 2.4 0.1 242.2 0.5 0.3 0.3 1.7 3.4 0.7 9.3 1.2 0.3 22.7 0.7 0.0 16.6 15.8 24.0 42.7 15.2 0.1 0.3 0.4 11.5 0.5 0.4 3.1 22.3 24.6 15.2 81.7 30.5 0.3 0.0 0.0 0.0 0.0 20.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 35.6 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 286.7 0.1 0.0 0.0 11.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.6 0.2 0.3 0.3 0.3 0.3 0.3 0.4 0.3 60.8 1227.5 89.3 0.0 0.0 0.5 139.6 111.5 36.5 0.0 2.0 1.5 6.4 1.5 405.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.7 93.8 12.5 23.5 0.0 0.0 0.1 0.0 0.2 47.9 1.1 8.5 6.3 0.0 1.4 0.0 0.6 0.0 0.1 0.0 48.8 0.0 0.3 0.9 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 6.9 0.0 1.1 763.9 0.0 0.0 3.0 23.3 0.1 0.1 71.4 4.1 0.8 1.8 0.0 0.0 163.0 CYSRT1 "C9orf169, MGC59937" ENSG00000197191 "Cysteine rich tail 1" A8MQ03 9 137224635-137226315 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 239.5" "Group enriched" "Detected in some" 10 "Pancreatic endocrine cells: 58.0;Squamous epithelial cells: 66.0" "Cancer enhanced" "Detected in all" "head and neck cancer: 23.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 25.1;CAPAN-2: 28.9;HaCaT: 33.3;HeLa: 30.6;MCF7: 49.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021883, HPA021886" Approved Approved "Nuclear speckles,Vesicles,Midbody" Yes No "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear speckles" "Vesicles, Midbody" "HPA021883: AB_1853190, HPA021886: AB_1853192" "unprognostic (1.35e-1)" "unprognostic (2.53e-2)" "unprognostic (8.31e-3)" "unprognostic (6.87e-3)" "unprognostic (2.14e-1)" "unprognostic (2.66e-2)" "unprognostic (8.11e-2)" "unprognostic (5.86e-2)" "unprognostic (3.45e-1)" "unprognostic (2.73e-1)" "unprognostic (1.24e-2)" "unprognostic (1.05e-1)" "unprognostic (6.24e-3)" "unprognostic (7.92e-3)" "unprognostic (1.99e-1)" "unprognostic (1.03e-1)" "unprognostic (2.29e-1)" 0.6 1.1 0.6 0.2 0.4 0.4 1.5 0.3 1.6 43.1 0.0 0.6 0.4 0.5 0.4 239.5 1.8 0.7 0.9 0.8 0.8 3.7 1.7 1.1 0.7 1.4 1.3 0.3 1.5 0.6 7.3 0.3 0.6 2.6 0.1 0.6 29.9 0.5 0.4 34.4 0.8 0.0 1.0 0.7 2.0 4.1 0.9 0.3 2.4 0.0 14.3 1.2 57.7 0.5 25.1 2.4 1.8 3.9 0.0 0.1 5.3 0.4 0.4 0.5 0.2 1.3 28.9 1.3 1.2 0.3 0.7 33.3 0.5 7.0 0.0 2.7 1.8 0.3 30.6 16.8 0.9 0.2 1.4 0.4 3.5 0.9 0.2 1.3 0.3 1.4 0.6 3.1 1.6 49.5 0.7 1.0 0.7 4.8 3.0 2.4 2.8 3.5 0.6 1.6 0.4 1.8 4.5 3.5 0.9 1.5 7.7 0.4 1.0 1.1 0.9 3.2 0.6 1.9 1.7 1.2 1.4 1.3 1.4 0.2 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.9 0.0 0.0 0.0 0.6 0.4 0.3 1.6 0.8 0.8 1.4 1.3 0.6 1.0 0.9 0.5 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.7 0.5 0.4 1.5 2.5 5.5 0.0 0.6 0.1 0.4 0.0 4.6 0.5 2.1 0.2 0.3 0.0 0.0 0.3 5.8 0.2 0.1 3.1 1.7 0.0 0.6 0.7 0.8 0.2 0.0 0.3 0.6 0.0 0.3 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.5 0.0 0.0 0.0 58.0 1.1 0.4 0.1 0.2 1.6 0.9 0.0 0.6 0.0 0.3 0.3 3.0 1.1 66.0 0.0 0.0 0.1 0.9 0.5 1.7 CZIB "C1orf123, FLJ20580" ENSG00000162384 "CXXC motif containing zinc binding protein" Q9NWV4 1 53214099-53220634 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Adipocytes: 29.2;Cardiomyocytes: 45.8;Cytotrophoblasts: 60.7;Extravillous trophoblasts: 76.7;Fibroblasts: 22.2;Hofbauer cells: 66.5;Syncytiotrophoblasts: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043835 Uncertain Approved "Vesicles,Mitotic spindle,Cytosol" Yes No 320000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Vesicles, Mitotic spindle" "HPA043835: AB_10796797" "unprognostic (1.09e-2)" "unprognostic (5.91e-2)" "unprognostic (2.03e-2)" "unprognostic (4.55e-2)" "unprognostic (5.43e-2)" "unprognostic (1.53e-1)" "unprognostic (9.20e-3)" "unprognostic (2.27e-1)" "unprognostic (5.52e-2)" "unprognostic (9.37e-3)" "unprognostic (1.46e-1)" "unprognostic (3.05e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (6.31e-3)" "unprognostic (1.39e-1)" "unprognostic (1.32e-1)" "unprognostic (2.43e-1)" 55.8 35.5 56.1 22.3 58.0 21.9 49.4 57.2 74.6 53.6 56.9 66.5 22.5 57.1 39.8 32.3 52.3 30.2 52.5 57.7 56.6 39.4 43.5 33.1 30.0 57.9 56.6 47.2 25.1 34.6 28.5 30.6 57.0 41.0 34.8 21.6 24.8 45.4 76.5 26.2 31.6 59.2 57.1 32.5 40.3 31.0 57.4 36.3 35.1 65.3 29.7 57.7 37.6 59.0 32.6 34.7 44.7 41.0 101.6 129.1 39.4 47.8 50.4 47.3 50.8 29.6 27.5 50.1 39.0 58.1 45.8 12.6 27.9 46.9 57.0 65.0 47.5 51.0 24.9 45.0 100.0 59.5 32.1 84.6 50.3 50.6 53.3 71.5 78.5 61.0 53.7 13.7 60.1 54.6 73.5 55.6 74.8 39.7 54.3 52.8 56.8 39.7 55.8 32.6 37.6 36.1 45.1 40.9 47.7 72.2 29.2 59.8 49.3 54.5 31.9 38.2 47.2 19.5 30.7 57.3 43.9 58.5 42.8 60.7 56.6 58.6 50.9 72.3 46.9 46.9 49.8 53.6 68.8 45.1 55.0 54.9 22.8 59.0 60.3 46.3 68.2 51.1 56.1 58.0 57.2 74.6 57.7 56.6 57.9 56.6 57.0 57.1 57.4 59.0 29.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.8 0.0 0.0 0.0 0.0 60.7 8.2 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 76.7 22.2 0.0 0.0 0.0 0.0 0.0 0.0 66.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.0 46.7 1.3 0.0 0.0 0.0 DAAM2 KIAA0381 ENSG00000146122 "Dishevelled associated activator of morphogenesis 2" Q86T65 6 39792298-39904877 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 245.9" "Group enriched" "Detected in many" 5 "Astrocytes: 275.6;Oligodendrocytes: 449.8;Sertoli cells: 151.2" "Group enriched" "Detected in all" 5 "glioma: 15.0;melanoma: 21.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HSkMC: 54.9;JURKAT: 30.4;LHCN-M2: 55.8;SK-MEL-30: 68.7;WM-115: 26.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051300, HPA054630" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Vesicles, Cytosol" "HPA051300: AB_2681430, HPA054630: AB_2682549" "unprognostic (7.53e-2)" "unprognostic (6.02e-3)" "unprognostic (4.49e-2)" "unprognostic (7.93e-2)" "unprognostic (8.24e-2)" "unprognostic (4.28e-2)" "unprognostic (2.43e-2)" "unprognostic (1.05e-3)" "unprognostic (1.33e-1)" "unprognostic (5.89e-2)" "unprognostic (2.17e-1)" "unprognostic (5.24e-2)" "prognostic unfavorable (2.79e-4)" "unprognostic (2.67e-2)" "unprognostic (8.54e-2)" "unprognostic (7.94e-2)" "unprognostic (8.54e-4)" 33.7 22.5 179.4 9.0 229.4 1.8 23.3 175.8 159.3 15.7 65.1 18.9 9.8 14.0 10.4 36.6 18.5 7.4 13.5 144.0 170.5 9.3 4.8 12.4 3.6 234.8 195.8 10.0 7.5 4.1 5.1 12.2 205.0 11.0 8.7 1.6 7.6 21.7 38.3 8.5 20.9 18.3 194.3 40.2 18.9 12.3 187.7 2.5 13.1 38.1 2.3 9.9 11.3 245.9 0.1 0.0 5.8 0.1 12.2 0.3 0.2 9.8 13.1 2.2 1.2 0.9 0.0 0.1 0.5 14.7 4.5 0.1 0.0 0.0 0.8 0.0 2.4 0.0 0.0 0.1 8.8 0.0 0.1 54.9 0.0 0.3 0.0 15.6 0.0 30.4 0.0 0.1 55.8 0.2 1.5 0.1 1.6 3.1 0.1 0.0 10.0 8.1 0.0 0.0 2.0 2.3 0.0 0.7 68.7 11.7 0.0 0.1 0.6 20.8 6.0 0.2 0.3 0.0 0.0 0.0 0.2 0.0 26.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 179.4 229.4 175.8 159.3 144.0 170.5 234.8 195.8 205.0 194.3 187.7 245.9 11.2 9.6 12.2 275.6 0.1 1.8 0.9 0.0 0.0 1.3 1.5 1.5 2.5 1.5 3.8 0.0 0.0 0.5 0.1 0.0 0.0 0.5 3.8 1.2 10.4 9.0 0.0 2.7 1.4 3.3 0.5 11.8 0.5 2.3 0.0 1.9 2.5 1.2 0.2 0.0 5.8 0.0 0.0 31.5 2.4 6.4 23.6 6.2 8.8 21.5 0.0 5.8 1.0 8.5 449.8 0.3 0.0 22.2 0.0 0.8 0.0 0.1 1.5 1.6 151.2 12.7 48.8 1.0 1.9 0.4 1.1 0.3 0.7 55.9 0.0 1.2 DAB1 ENSG00000173406 "DAB adaptor protein 1" O75553 1 56994778-58546734 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.8;intestine: 22.3;seminal vesicle: 10.0" "Group enriched" "Detected in some" 8 "Excitatory neurons: 460.3;Inhibitory neurons: 1170.3;Oligodendrocyte precursor cells: 814.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 2.1" "Lineage enhanced" "Detected in single" "T-cells: 2.1" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 54.0;HeLa: 18.6;NTERA-2: 23.4;RT4: 32.0;WM-115: 26.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032329, HPA052033, HPA067495" Enhanced Enhanced Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "CAB032329: AB_638973, HPA052033: AB_2681703, HPA067495: AB_2685852" "unprognostic (7.88e-2)" "unprognostic (1.02e-1)" "unprognostic (8.54e-2)" "unprognostic (2.09e-4)" "unprognostic (1.21e-1)" "unprognostic (1.18e-1)" "unprognostic (7.30e-4)" "unprognostic (3.90e-1)" "unprognostic (3.07e-2)" "unprognostic (1.47e-2)" "unprognostic (2.06e-3)" "unprognostic (1.27e-1)" "unprognostic (2.00e-3)" "unprognostic (1.78e-1)" "unprognostic (2.01e-1)" "unprognostic (1.44e-2)" "unprognostic (5.67e-2)" 2.0 1.7 4.3 0.4 5.3 0.0 0.3 16.8 8.8 1.6 0.0 0.8 15.8 0.5 0.4 0.6 1.6 0.7 1.8 10.6 5.4 0.3 7.7 0.4 0.2 2.1 3.9 1.2 0.4 0.0 0.2 0.0 2.0 3.9 0.3 5.4 0.9 10.0 0.1 0.1 22.3 0.3 2.3 0.2 1.0 0.4 5.1 0.1 0.3 0.1 0.1 1.2 0.9 1.9 0.0 0.0 10.6 0.0 0.1 0.2 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 54.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.8 0.0 0.0 0.0 0.0 2.0 0.1 23.4 0.0 0.0 6.0 0.0 0.2 0.0 32.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 0.6 0.1 0.0 2.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 4.3 5.3 16.8 8.8 10.6 5.4 2.1 3.9 2.0 2.3 5.1 1.9 0.7 0.0 0.0 30.0 0.1 0.0 0.1 0.1 0.0 23.7 0.1 0.3 3.2 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 8.6 8.2 0.6 0.3 0.0 0.0 460.3 0.0 0.0 0.4 4.6 12.8 0.0 0.0 0.7 5.1 0.1 21.9 1170.3 1.9 6.1 0.3 0.0 4.7 3.4 0.1 0.0 22.5 0.0 1.0 1.0 814.8 26.5 0.0 0.0 2.6 0.0 0.1 101.1 0.2 0.0 0.8 0.0 0.1 0.9 0.2 0.5 0.0 0.0 0.7 0.6 0.0 2.1 0.0 DAB2 DOC-2 ENSG00000153071 "DAB adaptor protein 2" P98082 5 39371675-39462300 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Differentiation, Endocytosis, Protein transport, Transport, Wnt signaling pathway" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 179.1;placenta: 226.6" "Group enriched" "Detected in many" 5 "Hofbauer cells: 1756.4;Proximal tubular cells: 1653.7;Syncytiotrophoblasts: 1324.5" "Cancer enhanced" "Detected in all" "renal cancer: 52.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 8 "plasmacytoid DC: 48.7" "Lineage enriched" "Detected in many" 8 "dendritic cells: 48.7" "Cell line enhanced" "Detected in many" "ASC diff: 220.1;ASC TERT1: 234.5;fHDF/TERT166: 356.8;TIME: 211.1;U-138 MG: 237.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009314, HPA028888" Enhanced Enhanced "Nucleoli fibrillar center,Vesicles,Plasma membrane" NA NA 130000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" "Nucleoli fibrillar center" "CAB009314: AB_638976, HPA028888: AB_2672814" "unprognostic (1.24e-1)" "unprognostic (7.28e-2)" "unprognostic (2.16e-1)" "unprognostic (1.25e-1)" "unprognostic (5.37e-3)" "unprognostic (7.01e-2)" "prognostic unfavorable (7.38e-6)" "unprognostic (3.11e-1)" "unprognostic (2.82e-1)" "unprognostic (2.78e-2)" "unprognostic (1.50e-1)" "unprognostic (1.87e-1)" "unprognostic (3.16e-2)" "prognostic unfavorable (9.67e-4)" "unprognostic (1.27e-2)" "unprognostic (2.24e-1)" "unprognostic (1.20e-1)" 76.9 113.6 7.3 33.1 8.3 4.1 48.2 13.4 13.1 48.4 26.2 33.2 13.5 32.5 116.8 16.8 21.6 50.1 20.0 7.5 7.7 179.1 27.3 53.3 33.2 14.6 10.0 34.0 22.8 10.1 7.9 226.6 12.6 13.0 54.5 11.6 24.2 19.8 11.4 21.2 25.6 47.8 7.8 58.5 16.6 10.6 20.1 20.9 23.5 16.4 19.0 44.6 20.6 10.8 0.2 8.3 12.9 27.9 220.1 234.5 16.0 145.7 149.5 56.3 92.5 108.1 0.5 0.1 8.8 356.8 54.8 0.3 2.0 5.2 78.9 0.2 4.2 19.9 191.1 35.5 52.4 0.2 24.3 146.5 0.2 91.7 16.5 87.2 172.4 9.9 0.0 5.0 95.2 0.6 2.1 0.3 8.9 4.1 15.8 5.4 32.7 0.0 37.8 3.2 0.1 0.4 17.4 9.3 79.2 20.4 0.6 4.9 211.1 237.9 26.1 27.7 11.9 0.2 0.1 0.3 82.6 18.1 31.5 5.8 2.3 0.5 2.1 4.6 0.1 0.1 0.3 1.4 6.3 0.2 0.2 1.7 3.2 1.7 1.3 48.7 0.4 12.7 7.3 8.3 13.4 13.1 7.5 7.7 14.6 10.0 12.6 7.8 20.1 10.8 100.2 38.5 42.2 0.0 14.5 14.5 1.2 15.3 3.4 1.1 38.3 26.7 55.1 70.1 9.9 95.6 70.9 170.8 83.8 29.6 197.6 75.7 1.4 31.7 161.0 116.9 9.7 10.1 11.0 2.0 20.1 139.5 3.6 36.4 25.3 50.6 187.4 3.7 1756.4 8.4 2.8 7.6 2.0 175.2 77.9 4.5 122.4 287.4 12.4 92.8 10.9 81.5 63.8 27.2 0.3 6.5 10.2 64.3 1.4 7.0 33.8 1653.7 7.5 3.5 6.6 62.4 50.4 0.5 4.8 3.5 13.4 1324.5 13.4 104.8 27.5 1.3 DACT3 "DAPPER3, MGC15476, RRR1" ENSG00000197380 "Dishevelled binding antagonist of beta catenin 3" Q96B18 19 46647551-46661182 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 23.9;Oligodendrocytes: 27.2;Smooth muscle cells: 22.9" "Cancer enhanced" "Detected in many" "glioma: 7.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 10.5;SH-SY5Y: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043053 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles Nucleoplasm "HPA043053: AB_10794769" "unprognostic (2.35e-1)" "unprognostic (3.08e-1)" "unprognostic (5.30e-3)" "unprognostic (5.08e-2)" "unprognostic (2.02e-1)" "unprognostic (1.09e-1)" "unprognostic (2.66e-1)" "unprognostic (2.03e-2)" "unprognostic (3.27e-2)" "unprognostic (2.03e-4)" "unprognostic (1.70e-1)" "unprognostic (2.67e-1)" "prognostic unfavorable (7.97e-8)" "unprognostic (1.59e-2)" "unprognostic (4.03e-2)" "unprognostic (3.54e-3)" "prognostic unfavorable (6.66e-4)" 9.1 3.3 42.1 5.9 42.0 1.4 5.4 41.1 54.4 34.7 3.6 53.9 3.9 48.2 14.3 7.4 37.4 7.2 27.5 48.6 33.4 5.9 2.6 14.0 1.1 45.4 40.1 17.0 1.1 1.9 4.1 1.7 39.9 19.7 6.7 5.8 1.7 24.6 2.2 4.1 13.0 31.6 34.7 6.8 18.0 18.7 46.3 0.5 4.8 2.9 0.9 39.0 15.9 58.0 0.2 0.2 5.6 5.3 1.9 1.5 0.5 3.1 5.2 1.0 1.5 0.2 0.3 0.5 2.0 10.5 1.0 0.3 3.6 0.1 1.0 0.3 1.9 1.2 0.8 0.2 2.7 0.1 2.1 4.9 0.1 1.3 0.1 0.6 0.4 0.7 1.8 1.8 0.9 0.4 0.2 1.4 2.2 0.0 0.8 4.6 1.3 0.3 0.2 0.3 2.1 24.6 0.4 0.2 0.4 5.7 0.4 0.5 0.4 2.6 3.2 2.6 0.5 1.6 0.5 0.8 0.5 0.8 1.9 2.6 0.3 0.3 0.2 0.1 0.1 0.3 0.2 0.2 0.1 0.5 0.2 0.2 1.6 0.7 0.2 0.3 0.2 0.1 42.1 42.0 41.1 54.4 48.6 33.4 45.4 40.1 39.9 34.7 46.3 58.0 1.9 6.4 5.5 13.7 0.2 2.3 1.5 0.0 0.0 16.5 1.0 2.4 17.8 1.5 0.7 0.0 2.1 5.4 0.5 0.3 0.0 0.0 23.9 0.4 9.3 3.1 1.8 0.0 9.2 0.0 2.6 7.4 0.0 0.8 6.3 0.5 1.8 0.2 1.1 1.7 16.7 0.2 2.0 1.6 9.2 8.6 7.8 1.4 3.6 7.5 1.2 9.2 2.1 15.1 27.2 0.1 1.2 14.7 0.1 1.0 0.2 0.3 0.2 6.3 6.6 2.3 22.9 2.3 2.5 0.4 3.3 9.9 1.0 4.3 0.2 1.0 DAG1 "156DAG, A3a, AGRNR, DAG" ENSG00000173402 "Dystroglycan 1" Q14118 3 49468703-49535618 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 207.9;Skeletal myocytes: 326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 280.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001960, CAB016353, HPA070563" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 84000000 "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Plasma membrane" Nucleoplasm "CAB001960: , CAB016353: AB_627292, HPA070563: " "unprognostic (1.58e-1)" "unprognostic (5.14e-1)" "unprognostic (6.71e-3)" "unprognostic (3.32e-1)" "unprognostic (7.39e-2)" "unprognostic (9.91e-2)" "unprognostic (1.67e-1)" "unprognostic (3.27e-2)" "unprognostic (8.18e-2)" "unprognostic (3.91e-2)" "unprognostic (5.70e-3)" "unprognostic (1.10e-1)" "prognostic favorable (2.59e-4)" "unprognostic (9.22e-2)" "unprognostic (1.99e-2)" "unprognostic (7.43e-2)" "unprognostic (1.57e-2)" 25.2 22.0 31.5 17.9 32.6 5.4 26.6 30.7 30.7 26.2 25.5 38.8 24.0 32.1 16.2 28.3 31.8 26.4 68.9 30.1 28.9 28.1 43.0 31.8 9.4 33.3 31.4 24.6 51.4 44.3 18.6 77.0 28.6 29.5 30.6 9.8 31.8 37.9 93.8 28.5 24.0 45.9 30.2 12.6 32.0 26.9 34.1 10.5 25.5 95.7 14.3 27.8 22.0 31.2 92.3 92.4 61.9 152.3 80.3 38.8 280.9 63.9 93.7 108.0 69.0 74.2 96.0 13.0 62.2 103.2 87.6 168.4 55.6 81.2 67.2 12.7 18.6 9.6 84.3 87.2 35.5 11.2 17.4 33.3 72.5 100.3 33.3 96.7 97.1 15.3 14.5 9.8 31.2 75.5 10.1 8.1 66.4 110.0 31.2 5.5 60.5 22.3 82.5 126.4 21.8 45.2 74.8 206.0 105.5 170.3 171.6 22.8 51.8 39.1 63.9 76.0 91.4 11.0 24.2 8.1 50.4 12.6 245.9 2.3 1.2 0.7 1.1 1.3 1.2 1.2 0.9 0.9 0.7 1.0 1.0 1.0 2.2 1.1 2.5 1.3 0.7 1.4 31.5 32.6 30.7 30.7 30.1 28.9 33.3 31.4 28.6 30.2 34.1 31.2 19.0 54.5 18.4 32.0 4.0 14.3 8.0 31.7 17.1 7.4 36.1 46.4 56.6 30.0 20.6 35.0 4.2 116.4 5.8 37.3 1.9 32.4 30.0 30.2 17.3 20.9 33.0 14.3 15.6 79.6 118.4 26.1 37.8 37.9 7.0 207.9 16.8 59.9 21.2 3.3 16.5 29.7 14.2 8.6 7.0 20.0 21.5 6.3 33.8 9.4 5.6 27.1 5.2 19.6 10.7 57.2 21.4 36.9 5.1 14.4 18.9 7.6 23.2 8.7 46.0 326.1 36.2 7.1 19.9 19.0 17.0 95.9 5.9 10.0 29.2 10.2 DAP ENSG00000112977 "Death associated protein" P51397 5 10679230-10761234 "Predicted intracellular proteins" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 193.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA029456 Uncertain Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "Vesicles, Mitochondria" Nucleoplasm "HPA029456: AB_10601262" "unprognostic (2.70e-2)" "unprognostic (3.48e-1)" "unprognostic (2.25e-1)" "unprognostic (1.88e-2)" "unprognostic (1.95e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (4.05e-2)" "unprognostic (1.19e-1)" "unprognostic (1.52e-3)" "unprognostic (3.50e-1)" "unprognostic (1.91e-2)" "unprognostic (3.03e-3)" "unprognostic (2.11e-1)" "unprognostic (2.39e-1)" "unprognostic (8.58e-3)" "unprognostic (2.04e-2)" 54.5 103.7 34.8 47.0 33.6 44.5 69.0 30.6 38.8 75.1 91.0 65.8 93.8 59.0 68.6 39.0 63.1 83.3 60.9 35.4 32.9 99.0 161.8 64.9 45.6 39.9 37.1 75.0 241.4 82.9 80.9 64.1 33.1 76.7 69.1 13.8 129.4 92.2 9.4 46.9 87.0 63.6 34.7 46.3 106.3 27.3 36.6 41.2 92.9 14.7 50.8 87.9 49.0 32.5 107.3 76.3 92.6 86.3 169.6 203.6 102.8 255.3 394.4 189.5 217.8 54.7 88.9 46.3 163.8 318.4 119.6 20.6 58.3 151.7 205.1 245.3 42.5 62.2 137.9 136.0 159.7 117.7 44.6 105.4 51.9 124.5 223.3 109.1 358.4 51.1 73.5 152.5 188.2 85.0 63.1 74.9 33.7 143.9 172.9 86.0 40.9 76.8 250.1 195.2 62.7 84.3 261.2 105.2 69.6 70.6 83.4 170.4 177.4 116.8 125.9 78.1 137.6 85.1 118.6 68.3 115.4 225.3 179.3 40.7 78.0 45.0 32.7 70.7 38.5 39.8 33.6 29.0 76.8 25.9 24.4 24.4 63.4 33.1 72.1 62.3 39.3 62.2 34.8 33.6 30.6 38.8 35.4 32.9 39.9 37.1 33.1 34.7 36.6 32.5 29.0 16.0 44.7 8.5 36.7 19.2 62.6 14.1 19.9 8.9 90.4 39.2 12.3 72.9 27.3 53.3 6.2 66.2 42.3 75.6 133.1 97.3 13.3 45.0 31.7 38.4 44.3 23.4 5.5 193.0 98.5 45.1 61.7 58.1 35.0 68.9 41.0 109.1 52.3 5.0 7.8 115.3 10.2 49.9 34.2 33.4 29.8 56.5 28.4 35.6 44.2 29.8 32.0 22.6 6.2 124.8 69.0 34.3 74.8 78.6 133.5 100.5 15.1 8.1 0.0 18.6 41.8 30.7 7.1 15.7 18.2 101.0 24.1 43.0 70.4 108.8 DAPK2 "DRP-1, MGC119312" ENSG00000035664 "Death associated protein kinase 2" Q9UIK4 15 63907036-64072033 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 50.2;thyroid gland: 41.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 86.6;Late spermatids: 112.5;Oligodendrocytes: 99.9;Proximal enterocytes: 64.0" "Cancer enriched" "Detected in many" 15 "thyroid cancer: 30.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "basophil: 94.3;eosinophil: 213.0;neutrophil: 65.9" "Lineage enriched" "Detected in many" 25 "granulocytes: 213.0" "Cell line enhanced" "Detected in many" "ASC diff: 10.6;HaCaT: 9.2;HMC-1: 18.3;MCF7: 9.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA071581 Supported "Golgi apparatus,Vesicles" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA071581: AB_2686421" "unprognostic (3.20e-2)" "unprognostic (4.07e-2)" "unprognostic (4.23e-2)" "unprognostic (1.95e-3)" "unprognostic (2.88e-2)" "unprognostic (1.30e-2)" "unprognostic (2.32e-1)" "prognostic favorable (5.63e-4)" "unprognostic (1.04e-1)" "unprognostic (3.18e-1)" "unprognostic (9.21e-2)" "unprognostic (8.51e-2)" "unprognostic (4.77e-7)" "unprognostic (5.98e-2)" "unprognostic (1.45e-1)" "unprognostic (3.20e-3)" "unprognostic (9.07e-2)" 12.5 2.2 5.9 2.7 7.6 15.9 8.8 5.9 8.1 6.7 4.3 9.8 20.6 1.6 0.2 3.3 1.7 1.5 28.0 5.5 6.7 4.5 2.0 20.0 3.1 6.2 6.8 0.9 2.7 0.9 1.6 0.4 6.6 5.1 6.6 0.4 7.5 3.6 50.2 8.1 21.3 1.7 6.0 7.8 9.9 3.1 6.6 1.5 41.9 19.6 2.6 2.4 9.5 9.5 3.1 2.3 6.1 1.5 10.6 0.5 0.0 2.1 6.7 1.1 1.2 1.0 1.6 0.2 0.7 6.7 3.7 9.2 3.8 0.1 0.6 0.2 0.2 1.3 4.5 0.1 0.1 0.1 18.3 1.1 7.9 0.4 0.2 7.0 0.7 0.1 0.4 0.1 0.7 9.7 0.0 0.4 0.7 3.1 2.2 2.9 0.0 0.3 0.0 3.2 0.4 0.3 0.4 1.2 0.0 1.5 5.2 0.4 0.4 0.9 1.0 1.4 1.8 0.6 0.2 0.0 0.0 3.0 0.3 94.3 0.2 213.0 2.1 0.1 0.9 1.3 0.6 2.2 0.2 0.4 0.0 1.4 65.9 2.7 0.1 8.6 0.1 1.3 5.9 7.6 5.9 8.1 5.5 6.7 6.2 6.8 6.6 6.0 6.6 9.5 24.9 86.6 22.3 5.2 4.8 11.6 7.0 8.7 0.6 0.1 9.4 7.4 46.2 1.5 14.6 0.0 0.0 0.1 22.6 45.2 1.9 9.1 25.3 3.0 1.6 6.4 8.4 0.8 15.9 35.6 0.2 8.7 16.3 7.8 15.2 1.3 5.7 1.3 0.4 5.0 2.1 17.0 6.1 1.3 0.8 112.5 3.1 3.2 0.0 15.0 0.3 2.1 2.1 11.1 99.9 9.4 30.6 5.7 0.4 12.0 64.0 0.3 2.8 0.3 13.1 7.6 4.5 2.6 4.9 0.5 4.1 0.1 14.9 1.9 19.6 14.0 DBF4B "ASKL1, chifb, DRF1, FLJ13087, ZDBF1B" ENSG00000161692 "DBF4 zinc finger B" Q8NFT6 17 44708608-44752264 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.0;Horizontal cells: 30.3;Oligodendrocytes: 30.9;Spermatocytes: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA048465, HPA077959" Approved Supported Nucleoplasm,Vesicles NA Yes "Cluster 52: Eosinophils - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm Vesicles "HPA048465: AB_2680405, HPA077959: " "unprognostic (2.44e-1)" "unprognostic (1.26e-1)" "unprognostic (6.37e-2)" "unprognostic (2.15e-3)" "unprognostic (1.62e-1)" "unprognostic (6.13e-2)" "unprognostic (1.53e-4)" "unprognostic (7.61e-2)" "unprognostic (1.54e-2)" "unprognostic (4.08e-2)" "unprognostic (8.43e-3)" "unprognostic (1.83e-1)" "unprognostic (4.23e-6)" "unprognostic (1.50e-1)" "unprognostic (3.36e-1)" "unprognostic (2.57e-1)" "unprognostic (1.39e-1)" 0.9 0.7 1.1 1.2 1.1 2.0 1.3 1.2 1.8 1.5 0.5 1.9 0.6 1.9 3.5 1.4 1.8 0.7 0.8 1.1 1.0 1.6 0.6 0.8 1.5 1.1 1.0 1.7 0.9 0.8 1.7 0.9 1.1 2.3 1.2 2.9 1.1 1.3 0.6 2.0 1.5 1.5 0.8 1.6 1.3 5.1 1.2 1.9 2.7 0.4 1.3 1.6 1.3 1.2 3.7 7.7 5.7 4.2 0.5 1.1 4.9 3.9 1.7 8.1 7.9 3.3 3.1 5.5 2.1 1.3 7.2 3.6 5.0 1.7 9.3 9.2 8.2 7.0 6.2 4.3 0.2 4.8 5.9 0.5 0.6 4.4 1.4 1.8 4.1 9.3 8.9 5.6 4.4 4.0 7.1 2.9 2.5 7.7 4.0 6.2 6.6 2.3 1.8 2.2 3.1 3.4 3.8 1.2 2.9 6.1 3.9 3.1 1.8 2.8 5.2 3.6 7.2 2.6 3.5 7.2 2.1 4.1 4.3 0.0 0.1 0.4 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.1 0.1 1.1 1.1 1.2 1.8 1.1 1.0 1.1 1.0 1.1 0.8 1.2 1.2 2.1 0.0 1.1 15.0 4.0 0.6 2.6 1.2 1.2 30.0 1.5 1.3 1.1 0.0 2.1 5.5 12.5 4.2 5.8 0.6 0.0 0.3 8.1 2.0 2.2 2.8 4.2 5.5 11.4 0.8 1.4 2.3 1.5 1.1 3.8 9.6 3.3 0.3 1.4 30.3 11.0 0.3 0.0 1.3 3.1 7.4 1.2 2.5 5.4 5.6 1.4 7.2 2.1 7.5 30.9 0.2 0.2 3.0 3.4 2.0 0.7 0.5 1.9 15.7 0.0 4.5 2.0 35.7 16.5 1.9 0.1 1.4 1.4 5.3 1.1 2.3 DBH DBM ENSG00000123454 "Dopamine beta-hydroxylase" P09172 9 133636363-133659329 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Catecholamine biosynthesis" "Monooxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "adrenal gland: 272.7;brain: 236.6" "Cell type enriched" "Detected in some" 6 "Hepatic stellate cells: 10.0" "Cancer enhanced" "Detected in some" "liver cancer: 1.7" "Region enriched" "Detected in many" 8 "pons: 236.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 346 "SH-SY5Y: 1826.4" "Region enriched" "Detected in some" 6 "pons and medulla: 22.1" "Region enriched" "Detected in single" 26 "pons: 18.5" "HPA002130, HPA005960, HPA070789" Enhanced Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" NA NA 1600000000 "Cluster 32: T-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 43: Cardiomyocytes - Nuclear processes" Vesicles "Endoplasmic reticulum" "HPA002130: AB_2666554, HPA005960: AB_1078628, HPA070789: AB_2686312" "unprognostic (1.93e-3)" "unprognostic (7.52e-3)" "unprognostic (8.53e-2)" "unprognostic (2.10e-2)" "unprognostic (2.18e-3)" "unprognostic (3.38e-3)" "unprognostic (3.39e-3)" "unprognostic (3.97e-2)" "unprognostic (1.71e-1)" "unprognostic (8.99e-2)" "unprognostic (5.80e-2)" "unprognostic (7.69e-2)" "unprognostic (2.81e-7)" "unprognostic (9.31e-2)" "unprognostic (6.77e-2)" "unprognostic (1.49e-2)" "unprognostic (5.06e-3)" 2.8 272.7 0.1 1.0 0.2 0.2 0.1 0.0 0.8 0.4 0.0 0.1 0.4 0.3 0.2 0.1 0.3 0.3 0.5 0.3 0.2 1.3 36.1 0.8 2.3 9.8 29.4 0.4 4.3 0.0 1.4 1.4 236.6 0.4 0.0 0.1 0.6 0.2 0.1 0.2 0.6 0.0 0.0 0.9 0.4 0.2 0.6 0.2 0.4 0.0 0.0 0.4 1.1 1.0 0.0 0.0 0.1 0.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.2 3.2 0.9 0.1 0.0 0.0 0.3 5.2 4.7 0.0 0.0 2.1 1826.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.8 0.3 0.2 9.8 29.4 236.6 0.0 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 10.0 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 DBNL "ABP1, HIP-55, SH3P7" ENSG00000136279 "Drebrin like" Q9UJU6 7 44044640-44069456 "Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Endocytosis, Immunity, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 338.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020265, HPA027735" Enhanced Supported "Vesicles,Plasma membrane" NA NA 3500000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" "Vesicles, Plasma membrane" "HPA020265: AB_1850723, HPA027735: AB_10603790" "unprognostic (9.57e-2)" "unprognostic (1.11e-1)" "unprognostic (1.04e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (2.12e-5)" "unprognostic (2.25e-1)" "unprognostic (6.18e-3)" "unprognostic (1.83e-1)" "unprognostic (5.88e-2)" "unprognostic (8.92e-2)" "unprognostic (5.76e-3)" "unprognostic (5.92e-2)" "unprognostic (2.11e-1)" "unprognostic (1.79e-1)" "unprognostic (2.10e-1)" "unprognostic (1.46e-1)" "unprognostic (9.51e-2)" 58.1 51.6 44.2 62.8 45.1 76.6 51.3 41.7 50.4 72.4 39.9 54.6 34.7 56.0 20.2 189.0 47.8 47.2 49.2 45.8 45.2 50.7 51.1 57.8 99.6 46.2 44.8 38.0 44.3 38.4 47.8 34.9 48.4 57.0 30.6 9.4 57.5 38.0 34.3 59.9 64.7 44.8 44.3 119.5 54.7 20.8 44.6 64.8 47.6 16.4 89.1 60.3 92.0 43.4 57.6 89.1 60.5 56.6 77.0 49.7 46.0 95.9 93.6 111.5 91.5 90.0 82.5 132.3 70.0 126.1 133.6 101.9 35.6 130.6 40.7 70.6 38.9 51.9 73.8 52.4 78.5 75.8 70.3 46.6 53.3 107.1 35.2 71.5 74.1 83.9 63.8 49.3 105.5 91.5 136.5 85.3 43.1 72.9 73.0 69.4 48.1 64.5 69.8 90.5 65.6 89.8 69.6 121.5 24.4 43.8 94.0 99.4 121.1 82.7 75.5 49.5 113.6 102.7 49.4 81.2 78.3 83.2 183.8 263.3 377.1 295.0 190.3 422.7 148.3 253.9 138.0 155.0 362.5 261.7 136.5 145.1 357.4 192.4 437.9 376.6 183.1 558.8 44.2 45.1 41.7 50.4 45.8 45.2 46.2 44.8 48.4 44.3 44.6 43.4 49.9 44.8 36.2 10.7 105.4 17.6 34.1 62.9 19.4 33.0 26.7 24.0 30.6 25.8 42.2 31.3 35.5 78.9 101.6 58.5 45.0 87.0 10.3 30.7 39.3 44.8 37.8 45.8 7.4 73.2 146.4 39.3 54.6 50.7 65.9 42.3 32.5 22.5 176.0 40.4 6.7 50.0 38.7 129.6 48.6 10.6 37.0 113.4 55.2 7.5 338.3 42.5 112.3 5.5 11.4 105.9 74.0 33.8 50.2 31.5 49.0 33.6 21.6 38.6 6.6 29.0 54.6 24.4 12.8 64.4 26.7 87.3 69.5 51.9 44.0 51.1 DBX2 FLJ16139 ENSG00000185610 "Developing brain homeobox 2" Q6ZNG2 12 45014672-45051099 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "brain: 9.3" "Group enriched" "Detected in some" 9 "Astrocytes: 11.4;Oligodendrocyte precursor cells: 14.1;Spermatogonia: 5.1" "Cancer enriched" "Detected in single" 32 "glioma: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065045, HPA066053" Uncertain Approved "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nuclear membrane" Vesicles "HPA065045: , HPA066053: AB_2685605" "unprognostic (1.13e-4)" "unprognostic (9.99e-2)" "unprognostic (7.82e-3)" "unprognostic (5.24e-2)" "unprognostic (5.62e-2)" "unprognostic (1.51e-1)" "unprognostic (9.22e-2)" "unprognostic (4.76e-2)" "unprognostic (1.64e-1)" "unprognostic (5.19e-1)" 0.4 0.0 3.6 0.0 4.0 0.0 0.2 3.7 3.7 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.4 3.6 0.1 0.0 0.0 0.0 8.2 4.6 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 9.3 0.0 0.0 0.6 5.2 0.0 0.2 0.2 0.0 0.0 0.1 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 4.0 3.7 3.7 3.4 3.6 8.2 4.6 5.6 9.3 5.2 7.4 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.7 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 5.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 DCAF15 "C19orf72, MGC99481" ENSG00000132017 "DDB1 and CUL4 associated factor 15" Q66K64 19 13952492-13961449 "Predicted intracellular proteins" "Immunity, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068351 Approved Vesicles,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 12: NES - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Mitochondria Vesicles "HPA068351: AB_2685977" "unprognostic (6.91e-2)" "unprognostic (6.55e-3)" "unprognostic (3.03e-2)" "unprognostic (5.18e-3)" "unprognostic (1.95e-1)" "unprognostic (1.89e-2)" "unprognostic (1.83e-3)" "unprognostic (9.72e-2)" "unprognostic (8.03e-2)" "unprognostic (1.21e-1)" "prognostic favorable (7.97e-4)" "unprognostic (1.98e-2)" "prognostic unfavorable (1.34e-5)" "unprognostic (7.97e-3)" "unprognostic (1.26e-1)" "unprognostic (1.07e-1)" "unprognostic (1.59e-1)" 17.6 10.7 5.9 10.3 6.0 20.5 18.1 7.1 7.9 18.7 4.7 18.1 6.9 17.0 4.3 24.0 16.7 4.5 18.6 6.0 5.6 16.2 13.9 18.6 13.5 5.6 5.2 15.5 13.7 7.1 16.5 7.3 5.2 17.0 5.2 3.6 16.1 5.3 22.9 30.2 23.4 5.1 4.9 33.4 14.0 44.7 5.6 14.6 17.0 8.6 10.8 15.6 21.6 5.4 18.9 11.5 29.5 16.2 3.1 4.5 13.5 12.7 8.8 26.1 25.9 20.4 7.9 17.3 14.4 12.3 15.4 16.7 18.9 12.0 9.2 21.0 33.8 21.3 21.0 21.4 6.5 17.8 30.2 5.9 10.9 19.3 8.6 9.4 13.1 27.4 22.9 24.8 11.6 28.7 32.0 33.0 35.2 12.7 17.8 29.2 10.4 11.8 14.1 14.3 18.8 19.3 11.4 8.1 10.7 12.1 10.5 22.7 9.2 17.8 13.1 28.3 24.1 17.4 20.7 18.3 11.4 25.8 15.6 0.2 0.3 0.9 0.3 0.3 0.2 0.3 0.2 0.3 0.2 0.4 0.1 0.3 0.6 0.1 0.2 0.4 0.6 0.2 5.9 6.0 7.1 7.9 6.0 5.6 5.6 5.2 5.2 4.9 5.6 5.4 19.5 0.0 0.0 6.8 19.7 4.8 10.5 6.9 8.6 17.3 8.9 10.7 2.9 10.0 3.8 9.2 8.4 13.7 24.4 9.6 1.9 11.0 5.0 7.0 7.8 10.9 7.7 9.4 5.2 10.3 15.1 7.5 13.7 7.0 1.3 15.0 7.1 3.4 15.7 15.2 3.4 5.7 4.1 8.1 7.0 9.5 18.3 14.3 1.8 8.4 13.8 9.2 16.5 7.1 5.5 9.9 9.6 12.0 18.3 6.4 4.5 4.7 3.9 13.9 6.6 6.0 7.9 35.6 19.9 10.0 9.8 13.8 21.2 10.4 7.9 8.9 DCHS2 "CDH27, CDHJ, CDHR7, FLJ20047, PCDH23, PCDHJ" ENSG00000197410 "Dachsous cadherin-related 2" Q6V1P9 4 154231742-154491799 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 1.7" "Cell type enhanced" "Detected in some" "Astrocytes: 63.0;Early spermatids: 20.7;Excitatory neurons: 30.3;Horizontal cells: 25.2;Inhibitory neurons: 13.2;Late spermatids: 19.4;Microglial cells: 13.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "U-2 OS: 4.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA064159 Uncertain Approved "Vesicles,Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Plasma membrane" "HPA064159: AB_2685201" "unprognostic (1.38e-2)" "unprognostic (1.51e-1)" "unprognostic (5.74e-3)" "unprognostic (5.93e-2)" "unprognostic (7.43e-3)" "unprognostic (1.29e-1)" "unprognostic (2.27e-4)" "unprognostic (1.18e-1)" "unprognostic (4.00e-1)" "unprognostic (1.61e-1)" "unprognostic (2.53e-3)" "unprognostic (1.62e-1)" "unprognostic (1.06e-3)" "unprognostic (3.13e-1)" "unprognostic (2.62e-1)" "unprognostic (1.49e-1)" "unprognostic (1.68e-3)" 0.0 0.1 0.6 0.0 0.8 0.0 0.1 0.3 0.5 0.9 0.0 1.7 0.0 1.4 0.0 0.0 0.9 0.1 0.0 0.4 0.8 0.1 0.0 0.1 0.0 0.5 1.3 0.7 0.0 0.0 0.6 0.0 0.3 0.4 0.0 0.1 0.1 0.2 0.0 0.2 0.3 0.1 0.7 0.0 1.2 1.1 1.1 0.0 0.0 0.0 0.0 0.6 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.3 0.5 0.4 0.8 0.5 1.3 0.3 0.7 1.1 1.4 0.0 0.0 0.0 63.0 0.0 0.4 0.2 0.8 0.0 0.4 0.8 0.6 1.9 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 20.7 0.1 0.5 0.3 6.7 0.0 30.3 0.0 0.0 1.8 3.6 0.0 0.0 1.2 0.0 0.0 0.1 25.2 13.2 0.1 0.0 0.0 0.7 19.4 0.6 0.0 0.0 13.1 0.0 0.2 0.0 6.6 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.9 0.2 0.0 0.3 0.5 1.7 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.0 DCLK3 "DCAMKL3, DCDC3C, KIAA1765" ENSG00000163673 "Doublecortin like kinase 3" Q9C098 3 36712422-36764349 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.9;testis: 2.8" "Cell type enriched" "Detected in some" 6 "Early spermatids: 53.8" "Cancer enriched" "Detected in single" 5 "testis cancer: 1.2" "Region enhanced" "Detected in some" "basal ganglia: 3.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA040685, HPA053234" Approved Approved Vesicles,Cytosol NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol Vesicles "HPA040685: AB_2732487, HPA053234: " "unprognostic (9.09e-3)" "unprognostic (1.41e-3)" "unprognostic (2.75e-1)" "unprognostic (2.66e-2)" "unprognostic (2.41e-1)" "unprognostic (1.80e-1)" "unprognostic (1.40e-2)" "unprognostic (1.08e-2)" "unprognostic (1.96e-2)" "unprognostic (1.86e-2)" "unprognostic (2.05e-1)" "unprognostic (7.07e-2)" "unprognostic (6.11e-5)" "unprognostic (7.94e-3)" "unprognostic (5.80e-2)" "unprognostic (3.25e-3)" "unprognostic (1.36e-2)" 0.5 0.1 0.9 0.4 3.9 0.1 0.2 0.1 1.8 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.8 0.7 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.1 0.2 1.0 0.3 0.0 0.0 0.1 1.5 0.1 0.0 0.9 0.1 0.1 0.3 1.4 0.0 0.0 2.8 0.7 1.3 0.3 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 3.9 0.1 1.8 0.8 0.7 0.3 0.2 0.0 1.4 0.7 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 53.8 0.1 0.1 0.5 0.0 0.0 1.6 0.0 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.0 2.0 0.0 0.9 0.0 0.0 0.0 0.4 8.9 0.3 0.1 0.0 0.0 0.0 0.9 0.0 0.5 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.1 3.3 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DCP1B FLJ31638 ENSG00000151065 "Decapping mRNA 1B" Q8IZD4 12 1946053-2004535 "Predicted intracellular proteins, Predicted membrane proteins" "Nonsense-mediated mRNA decay" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 36.2;Early spermatids: 55.2;Oligodendrocyte precursor cells: 37.7;Oligodendrocytes: 35.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Lineage enriched" "Detected in all" 5 "T-cells: 27.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039709 Approved Supported Vesicles,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 5: NTERA-2 - Transcription" "Cluster 64: Astrocytes - Nervous system maintenance" "Vesicles, Cytosol" "HPA039709: AB_10672901" "unprognostic (9.60e-2)" "unprognostic (7.19e-3)" "unprognostic (4.37e-3)" "unprognostic (2.13e-1)" "unprognostic (7.00e-2)" "unprognostic (1.08e-1)" "unprognostic (8.94e-2)" "unprognostic (3.26e-1)" "unprognostic (3.13e-1)" "unprognostic (1.53e-2)" "unprognostic (5.87e-2)" "unprognostic (1.83e-1)" "unprognostic (1.08e-2)" "unprognostic (3.98e-2)" "unprognostic (1.46e-1)" "unprognostic (1.84e-2)" "unprognostic (7.42e-2)" 9.2 16.4 3.4 3.4 3.4 1.6 8.8 3.0 3.6 15.0 3.9 26.2 3.0 21.9 5.8 6.6 13.8 4.0 4.5 3.2 3.6 7.9 10.0 7.9 4.8 2.9 3.0 13.1 9.0 5.5 13.6 3.7 2.9 14.4 5.0 5.0 7.7 6.7 10.5 8.1 10.2 9.2 2.9 9.2 11.9 20.7 3.5 6.7 9.4 5.1 4.6 18.2 10.9 3.1 0.1 3.8 6.9 5.3 8.5 10.7 11.5 4.7 9.2 5.8 7.1 0.6 6.0 9.4 1.6 6.9 5.0 0.0 4.6 5.0 5.1 15.8 5.0 3.9 3.0 5.6 11.3 5.6 4.5 8.1 8.1 5.2 4.5 12.0 9.6 7.2 2.5 3.7 7.1 4.5 7.8 4.6 15.0 3.4 1.4 4.6 3.3 1.7 6.8 0.0 1.0 5.0 4.0 3.3 3.4 15.4 3.4 5.1 5.7 2.8 10.0 6.4 4.9 3.1 2.5 6.5 6.6 3.8 7.1 5.3 2.9 0.3 10.0 4.2 12.5 5.1 10.3 9.8 5.4 4.9 7.8 10.2 0.5 5.9 5.0 2.6 27.3 5.5 3.4 3.4 3.0 3.6 3.2 3.6 2.9 3.0 2.9 2.9 3.5 3.1 4.9 6.4 4.6 36.2 6.4 0.9 4.1 7.5 5.2 6.4 4.0 5.0 2.5 1.5 5.7 7.3 10.4 6.5 5.1 4.0 13.7 7.3 55.2 6.6 8.7 5.8 2.4 3.0 24.3 4.2 4.8 7.6 8.2 2.8 5.7 12.2 3.3 5.9 5.7 6.7 28.9 4.6 14.2 3.5 0.9 19.8 5.6 3.7 1.8 17.8 6.5 4.1 2.1 37.7 35.3 4.9 5.8 9.4 5.8 3.0 8.1 7.2 5.2 7.0 0.0 3.7 7.1 23.6 10.2 4.5 2.4 2.9 8.6 10.3 5.1 2.9 DCT TYRP2 ENSG00000080166 "Dopachrome tautomerase" P40126 13 94436811-94479682 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Melanin biosynthesis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "skin 1: 107.4" "Cell type enriched" "Detected in some" 23 "Melanocytes: 3552.1" "Cancer enriched" "Detected in some" 215 "melanoma: 155.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 272 "SK-MEL-30: 257.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA010742, HPA010743, HPA010800, CAB017634" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Vesicles "CAB017634: AB_1130818, HPA010742: , HPA010743: AB_1847519, HPA010800: AB_1847520" "unprognostic (5.99e-2)" "unprognostic (1.67e-2)" "unprognostic (1.54e-2)" "unprognostic (3.17e-2)" "unprognostic (2.45e-2)" "unprognostic (3.35e-2)" "unprognostic (2.15e-2)" "unprognostic (2.81e-2)" "unprognostic (6.07e-2)" "unprognostic (1.81e-1)" "unprognostic (3.64e-3)" "unprognostic (1.06e-2)" "unprognostic (6.18e-5)" "unprognostic (6.97e-2)" "unprognostic (9.87e-2)" "unprognostic (1.22e-3)" "unprognostic (2.42e-1)" 0.4 0.4 0.6 0.0 1.0 0.1 3.0 0.4 0.7 0.2 0.2 0.3 0.0 0.3 0.9 0.0 0.9 0.1 0.1 0.6 0.6 0.2 0.2 0.1 0.0 0.6 0.6 0.4 0.4 0.0 1.6 0.0 0.5 0.3 0.0 0.9 1.5 0.3 0.4 107.4 0.1 0.1 0.6 0.1 0.1 0.6 0.6 0.5 0.2 0.1 0.0 0.2 0.3 0.5 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 257.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.2 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 0.4 0.7 0.6 0.6 0.6 0.6 0.5 0.6 0.6 0.5 0.0 0.0 0.0 23.5 0.0 152.3 0.1 0.0 0.0 1.0 0.3 0.5 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.5 0.1 1.2 0.0 0.0 16.1 0.2 0.0 1.4 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.0 25.5 23.8 0.9 0.0 3552.1 1.9 0.0 3.5 0.0 6.6 2.4 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.5 1.0 0.5 0.8 0.0 33.4 0.0 0.9 0.1 0.0 0.0 DCUN1D4 KIAA0276 ENSG00000109184 "Defective in cullin neddylation 1 domain containing 4" Q92564 4 51843000-51916837 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 111.9;Oligodendrocytes: 131.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036483, HPA036484" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles Nucleoplasm "HPA036483: AB_10670719, HPA036484: AB_10671843" "unprognostic (3.16e-2)" "unprognostic (2.65e-1)" "unprognostic (2.77e-3)" "unprognostic (1.41e-1)" "unprognostic (5.61e-2)" "unprognostic (1.61e-1)" "unprognostic (2.80e-2)" "unprognostic (1.37e-1)" "unprognostic (8.47e-3)" "unprognostic (1.61e-3)" "unprognostic (3.88e-3)" "unprognostic (1.83e-2)" "unprognostic (2.93e-3)" "unprognostic (2.14e-1)" "unprognostic (5.25e-2)" "unprognostic (1.10e-3)" "unprognostic (1.40e-1)" 14.0 17.8 14.5 7.3 14.1 2.8 9.8 14.4 20.3 13.3 8.1 15.0 5.9 13.6 11.5 10.4 12.7 11.4 12.1 13.4 17.3 14.9 28.9 9.1 7.5 16.0 16.2 16.0 9.1 9.5 15.7 6.9 17.2 12.0 8.5 15.7 13.4 16.9 11.8 7.7 9.7 17.3 14.2 9.4 13.3 17.0 18.9 6.5 13.2 11.4 6.1 16.9 10.9 16.4 10.6 18.9 25.5 36.7 25.6 27.5 9.8 31.1 23.2 18.0 15.9 11.8 12.1 8.1 20.1 35.2 23.5 11.2 31.0 19.8 27.8 4.9 9.5 13.8 14.9 28.7 54.9 20.4 17.9 25.1 23.7 19.6 17.9 27.0 19.2 7.4 15.6 5.9 35.3 15.2 24.1 13.6 14.5 21.1 15.1 11.4 12.2 4.4 23.1 12.4 14.4 15.6 13.1 17.8 28.9 13.9 18.4 12.3 28.8 24.0 19.7 19.7 25.7 11.1 18.1 7.3 16.6 18.8 14.4 6.8 3.6 8.8 5.7 3.3 8.5 3.6 6.4 6.5 2.5 2.4 6.0 6.8 1.4 3.7 2.4 1.5 3.2 4.4 14.5 14.1 14.4 20.3 13.4 17.3 16.0 16.2 17.2 14.2 18.9 16.4 13.1 6.4 14.1 86.2 9.7 37.2 19.2 16.5 16.5 23.3 18.1 11.7 40.6 14.3 13.2 16.5 16.7 5.0 9.8 14.9 13.7 10.6 76.3 10.7 16.1 17.9 6.7 11.8 90.9 12.2 8.5 23.1 21.9 10.0 13.3 18.9 17.2 35.8 8.2 30.3 88.6 7.2 12.2 7.3 18.4 111.9 14.9 7.2 32.0 51.5 5.3 14.9 15.5 69.4 131.4 13.3 10.9 25.9 6.3 17.2 8.9 24.1 18.1 17.8 0.0 13.4 20.8 24.6 25.5 17.3 33.2 3.4 11.1 12.4 8.9 15.0 DDX31 "FLJ13633, FLJ14578, FLJ23349, PPP1R25" ENSG00000125485 "DEAD-box helicase 31" Q9H8H2 9 132592997-132670401 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 26.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020891 Supported "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoli "Golgi apparatus, Vesicles" "HPA020891: " "unprognostic (5.71e-2)" "unprognostic (1.76e-2)" "unprognostic (2.56e-1)" "unprognostic (7.91e-2)" "unprognostic (5.79e-2)" "unprognostic (9.94e-2)" "prognostic unfavorable (1.68e-7)" "unprognostic (1.34e-1)" "unprognostic (2.02e-2)" "unprognostic (1.66e-1)" "unprognostic (3.90e-2)" "unprognostic (9.57e-3)" "unprognostic (4.57e-3)" "unprognostic (2.24e-2)" "unprognostic (1.22e-1)" "unprognostic (1.38e-1)" "unprognostic (2.03e-1)" 3.9 3.8 3.3 5.3 3.9 4.2 6.3 8.8 3.2 4.8 4.0 3.9 3.1 4.5 5.0 5.7 5.2 3.6 3.3 2.8 3.7 6.0 5.5 4.5 6.6 5.1 3.8 9.9 5.8 5.4 4.2 3.5 5.7 5.4 4.7 3.2 8.2 4.3 6.1 8.4 4.2 4.2 2.9 4.8 4.0 6.0 3.6 5.5 13.8 4.2 7.2 5.2 4.9 4.7 12.4 22.2 10.8 14.4 12.4 11.1 20.4 12.9 12.2 19.2 14.5 24.9 24.1 29.9 11.2 11.7 20.8 33.5 32.8 14.6 15.4 18.4 12.3 16.4 19.5 13.1 14.9 29.7 12.8 9.9 19.5 19.7 27.5 7.5 12.7 22.1 30.6 11.4 16.1 26.3 20.6 15.9 26.2 35.4 22.2 21.4 19.3 34.6 17.5 11.4 18.8 13.5 23.4 20.2 18.0 12.2 42.8 8.4 11.1 32.5 15.0 18.7 19.8 5.5 18.8 23.5 12.0 18.2 25.2 0.0 1.1 1.2 3.1 1.6 2.4 2.1 2.9 2.4 2.5 2.7 3.6 2.7 0.2 2.0 1.1 1.6 2.0 1.7 3.3 3.9 8.8 3.2 2.8 3.7 5.1 3.8 5.7 2.9 3.6 4.7 3.3 6.4 6.0 16.6 7.2 5.6 4.5 3.0 9.1 4.3 5.9 8.1 4.4 0.0 10.2 7.3 4.2 5.7 4.7 3.6 1.9 6.2 4.1 3.9 6.6 3.6 24.6 1.7 9.7 5.4 6.8 4.4 4.1 4.6 1.3 6.1 2.9 4.1 5.2 1.7 13.9 5.8 6.1 2.9 1.8 3.0 18.0 2.9 1.8 5.6 4.5 1.7 8.2 26.7 17.1 5.9 1.2 13.2 5.7 5.8 0.7 7.1 5.7 3.7 0.0 4.1 3.4 14.0 13.7 8.8 6.3 3.0 5.0 5.7 6.1 3.5 DEFA5 "DEF5, HD-5" ENSG00000164816 "Defensin alpha 5" Q01523 8 7055304-7056739 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 768 "intestine: 9759.8" "Group enriched" "Detected in some" 4 "Proximal enterocytes: 1740.2;Undifferentiated cells: 1753.0" "Cancer enhanced" "Detected in many" "cervical cancer: 181.1;colorectal cancer: 147.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "BEWO: 28.3;NB-4: 24.2;RPMI-8226: 26.6;SH-SY5Y: 19.6;U-2197: 8.5" "HPA015309, HPA015775, CAB069919" Enhanced Approved Vesicles,Midbody "Secreted to digestive system" Yes NA 110000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" Vesicles Midbody "CAB069919: AB_905358, HPA015309: , HPA015775: AB_1847594" "prognostic favorable (9.44e-5)" "unprognostic (3.91e-2)" 0.3 0.4 0.1 12.7 0.1 0.2 0.5 0.1 0.5 0.0 0.1 56.6 5185.1 3.9 0.1 0.8 0.0 0.0 0.4 0.1 0.2 0.2 1.1 0.4 6.0 0.1 0.2 0.4 0.8 0.0 1.1 0.0 0.2 0.7 0.2 0.1 0.7 0.0 0.3 0.3 9759.8 0.1 0.1 0.4 0.9 0.8 0.2 0.4 0.3 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 28.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.2 0.0 0.0 0.0 0.0 0.0 26.6 0.0 0.0 2.5 19.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.5 0.1 0.2 0.1 0.2 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.3 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.1 325.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.1 399.9 0.0 0.0 0.0 1740.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.4 0.0 1753.0 0.0 DENND1A "FAM31A, FLJ21129, KIAA1608" ENSG00000119522 "DENN domain containing 1A" Q8TEH3 9 123379654-123930152 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 258.9;Excitatory neurons: 188.2;Inhibitory neurons: 175.8;Late spermatids: 88.5;Microglial cells: 178.0;Oligodendrocyte precursor cells: 165.4;Oligodendrocytes: 145.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 9 "dendritic cells: 12.1;granulocytes: 20.4;monocytes: 21.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020481 Approved Vesicles,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 64: Astrocytes - Nervous system maintenance" "Vesicles, Cytosol" "HPA020481: AB_2092106" "unprognostic (1.35e-1)" "unprognostic (3.96e-2)" "unprognostic (2.00e-1)" "unprognostic (4.25e-2)" "unprognostic (1.62e-2)" "unprognostic (1.47e-1)" "unprognostic (1.34e-1)" "unprognostic (3.19e-3)" "unprognostic (2.14e-2)" "unprognostic (2.14e-2)" "unprognostic (2.48e-3)" "unprognostic (5.63e-2)" "prognostic favorable (4.11e-5)" "unprognostic (1.25e-1)" "unprognostic (1.51e-1)" "unprognostic (9.66e-2)" "unprognostic (4.31e-2)" 8.5 8.3 8.2 10.3 8.3 27.0 7.1 2.7 10.3 7.9 6.8 10.6 11.3 8.3 4.6 7.7 8.7 7.2 7.3 8.1 6.2 11.4 10.8 6.9 9.0 5.6 6.0 7.9 6.2 11.9 10.2 11.3 4.9 7.7 9.6 10.3 6.1 7.6 8.4 6.9 12.6 9.9 4.8 14.2 6.9 9.5 6.4 7.1 10.8 4.8 6.2 7.6 6.5 5.7 29.0 16.7 14.7 28.0 9.8 15.3 68.3 27.4 41.0 22.9 19.6 23.0 12.5 23.1 5.5 22.3 30.1 15.9 12.6 19.9 22.2 9.8 9.7 10.9 39.1 17.1 13.2 13.2 7.0 14.2 17.6 18.9 32.2 8.0 20.6 21.8 30.3 17.2 18.7 16.5 15.8 19.1 29.4 33.1 25.2 24.3 14.4 19.5 11.4 10.1 31.1 25.3 22.1 14.4 16.9 9.6 19.8 32.8 9.7 24.5 9.4 28.9 14.6 26.0 21.7 16.0 20.6 25.9 16.5 20.4 21.1 4.3 1.8 14.6 0.9 1.7 1.3 0.8 12.1 1.8 0.8 1.0 12.8 0.8 12.8 1.9 0.6 5.3 8.2 8.3 2.7 10.3 8.1 6.2 5.6 6.0 4.9 4.8 6.4 5.7 6.4 0.0 1.5 258.9 10.0 5.1 2.6 2.5 1.8 16.1 4.8 4.3 7.7 7.2 1.7 16.5 16.7 10.0 6.8 25.3 5.9 4.3 35.1 5.0 8.2 10.5 12.0 20.2 188.2 5.1 32.2 7.6 20.9 3.9 4.5 8.8 7.5 14.5 18.0 32.0 175.8 7.6 2.0 21.4 8.2 88.5 14.6 18.7 3.6 178.0 18.7 11.6 5.2 165.4 145.2 6.1 9.5 11.3 13.1 5.3 18.3 16.0 2.9 13.1 0.0 6.7 5.9 3.8 1.4 3.8 2.8 8.8 5.3 4.5 7.8 3.9 DENND3 KIAA0870 ENSG00000105339 "DENN domain containing 3" A2RUS2 8 141117278-141195808 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 106.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 157.0;Microglial cells: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 34.6;neutrophil: 39.8" "Group enriched" "Detected in many" 5 "granulocytes: 39.8;monocytes: 10.0" "Cell line enhanced" "Detected in many" "HDLM-2: 64.6;HeLa: 89.5;U-937: 58.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA024491, HPA041668" Approved Approved Vesicles,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" "HPA024491: AB_2671581, HPA041668: " "unprognostic (2.27e-1)" "unprognostic (9.62e-2)" "unprognostic (9.47e-3)" "unprognostic (1.66e-1)" "unprognostic (6.96e-2)" "unprognostic (1.13e-1)" "unprognostic (1.53e-1)" "unprognostic (2.05e-1)" "unprognostic (1.55e-1)" "unprognostic (7.07e-3)" "unprognostic (2.71e-2)" "unprognostic (2.25e-2)" "unprognostic (7.74e-2)" "unprognostic (1.95e-1)" "unprognostic (2.02e-1)" "unprognostic (4.51e-2)" "unprognostic (5.42e-2)" 42.8 8.9 21.7 27.2 18.8 106.4 28.2 12.2 28.4 22.9 14.7 36.2 5.7 17.8 2.1 7.5 19.1 13.6 24.9 19.9 17.7 21.5 6.5 57.9 28.6 33.6 24.7 15.1 7.6 4.1 10.0 15.1 25.7 16.9 7.8 3.7 18.2 8.5 13.8 15.6 23.7 8.3 22.7 43.9 15.8 6.1 21.2 7.1 20.6 11.7 25.1 12.4 17.6 31.4 16.4 14.8 1.0 3.1 4.4 6.4 2.4 8.5 27.4 3.8 3.0 4.6 15.3 4.2 22.8 17.5 7.5 7.8 4.2 10.0 2.7 64.6 3.6 17.3 89.5 1.4 3.9 17.2 2.4 0.5 5.1 4.2 5.3 9.2 21.1 7.8 0.2 40.7 2.9 5.2 2.6 24.1 1.1 3.2 16.6 2.9 0.8 16.6 14.8 5.6 4.7 3.0 1.8 1.3 1.1 7.3 6.8 27.6 16.7 0.7 6.8 10.6 0.3 8.0 37.0 1.3 2.6 58.6 1.0 24.3 5.4 34.6 0.8 8.0 0.8 5.0 0.6 0.3 4.1 4.3 0.1 0.2 39.8 2.7 10.0 0.1 0.2 3.5 21.7 18.8 12.2 28.4 19.9 17.7 33.6 24.7 25.7 22.7 21.2 31.4 49.0 157.0 35.2 2.6 39.7 15.7 7.6 11.7 7.4 4.5 6.3 2.0 10.1 10.0 18.8 22.0 4.2 0.7 29.5 18.3 1.9 3.5 6.1 15.1 8.1 31.7 4.8 5.7 53.9 3.5 0.6 4.8 16.8 14.5 10.8 1.9 16.4 0.3 24.4 1.7 5.2 7.9 4.1 55.6 22.2 2.8 1.5 39.7 8.8 79.6 33.0 0.7 21.6 1.5 1.1 11.0 9.9 0.7 38.8 20.3 1.5 2.7 15.1 0.5 39.5 2.1 21.5 8.7 8.5 2.9 9.1 0.5 12.5 0.6 4.1 6.3 DENND4C "bA513M16.3, C9orf55, C9orf55B, FLJ20686, RAB10GEF" ENSG00000137145 "DENN domain containing 4C" Q5VZ89 9 19230435-19374281 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 120.9;Oligodendrocyte precursor cells: 107.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014917, HPA015096" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 36: HEL - Hemostasis" "Cluster 59: Non-specific - Transcription" "Golgi apparatus, Vesicles, Cytosol" "HPA014917: AB_2261659, HPA015096: AB_1845831" "unprognostic (4.57e-2)" "unprognostic (1.73e-2)" "unprognostic (6.81e-2)" "unprognostic (1.71e-1)" "unprognostic (1.87e-2)" "unprognostic (1.48e-1)" "unprognostic (2.43e-2)" "unprognostic (3.38e-1)" "unprognostic (1.14e-1)" "unprognostic (1.02e-1)" "unprognostic (3.20e-2)" "unprognostic (2.39e-1)" "prognostic favorable (3.51e-5)" "unprognostic (3.27e-1)" "unprognostic (1.31e-1)" "unprognostic (1.13e-1)" "unprognostic (2.29e-1)" 21.7 11.9 5.9 9.2 7.0 10.6 21.7 14.1 6.3 17.2 8.0 17.4 25.1 17.2 14.3 14.5 16.4 13.8 14.5 5.3 5.6 13.9 15.2 18.0 11.8 5.9 5.7 21.4 12.9 19.0 8.7 19.6 5.7 16.1 19.8 11.8 15.1 13.4 10.6 29.6 22.4 14.6 5.8 12.7 19.8 11.2 7.2 17.7 17.3 12.4 11.2 16.6 16.0 6.6 17.7 17.5 11.7 15.3 26.6 28.5 21.4 10.0 14.9 10.2 13.7 8.4 11.6 7.5 8.3 13.6 11.8 9.4 13.7 9.4 12.0 47.2 7.8 34.4 18.5 10.4 13.4 8.3 18.8 11.7 18.7 9.0 15.5 21.6 20.2 9.9 9.4 8.5 13.1 7.4 13.8 18.8 9.0 24.7 8.5 12.6 6.6 10.9 29.2 34.1 10.9 8.5 8.4 20.1 7.4 11.0 12.1 11.3 18.5 8.9 5.2 10.0 10.5 5.8 14.9 4.0 7.7 7.6 5.2 8.3 1.6 1.9 5.4 0.8 7.0 1.7 4.6 5.5 3.1 2.3 4.3 5.0 0.9 6.4 0.9 3.2 3.8 2.4 5.9 7.0 14.1 6.3 5.3 5.6 5.9 5.7 5.7 5.8 7.2 6.6 28.6 9.6 11.5 85.8 21.3 51.2 16.7 18.0 65.4 20.9 16.0 11.0 12.4 14.3 21.6 16.5 60.5 29.4 22.6 26.6 1.9 9.8 7.7 12.7 15.5 22.9 19.8 9.7 78.6 12.5 13.5 24.0 47.4 20.4 27.1 24.8 51.0 11.5 19.0 23.5 87.2 22.6 24.4 23.9 22.0 5.2 18.6 32.2 21.4 120.9 8.5 13.6 27.8 107.1 69.1 12.1 20.9 20.3 14.1 19.4 26.4 4.9 21.6 16.3 0.0 19.5 16.2 3.3 6.8 30.9 49.3 16.1 28.2 12.0 23.3 23.2 DENND5A "FLJ22354, FLJ33829, FLJ43455, KIAA1091, RAB6IP1" ENSG00000184014 "DENN domain containing 5A" Q6IQ26 11 9138825-9265959 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 136.2;Oligodendrocytes: 287.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052923, HPA055009" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Vesicles" "HPA052923: AB_2681989, HPA055009: AB_2682669" "unprognostic (5.28e-3)" "unprognostic (1.42e-1)" "unprognostic (1.17e-1)" "unprognostic (1.28e-2)" "unprognostic (4.03e-1)" "unprognostic (3.48e-1)" "prognostic unfavorable (5.05e-6)" "unprognostic (1.84e-1)" "unprognostic (2.96e-1)" "unprognostic (1.02e-1)" "unprognostic (5.15e-2)" "unprognostic (3.10e-1)" "prognostic unfavorable (1.14e-6)" "unprognostic (9.86e-3)" "unprognostic (1.03e-1)" "unprognostic (4.32e-1)" "unprognostic (1.40e-2)" 45.8 23.5 72.4 23.2 90.5 21.7 36.3 85.0 80.7 36.1 45.5 44.2 5.8 38.5 14.1 17.4 37.5 23.3 58.0 65.1 85.4 25.5 15.7 46.1 16.8 81.5 86.6 30.2 23.2 18.5 20.5 28.8 77.0 24.5 12.9 34.7 19.5 40.0 26.7 17.3 20.2 47.5 74.9 31.4 23.7 15.8 87.3 28.0 22.0 33.7 15.9 40.4 25.1 81.3 18.8 23.3 63.7 56.1 113.0 92.0 61.7 69.2 99.8 85.7 104.5 16.4 13.6 0.0 30.5 129.0 82.4 12.7 64.3 22.5 111.4 73.0 30.9 6.2 32.2 34.5 61.0 34.4 13.9 76.8 11.5 51.1 74.6 59.7 83.8 21.9 33.6 0.3 101.9 11.0 19.4 15.1 19.7 3.2 28.6 34.2 46.1 0.3 41.6 13.4 15.9 32.1 65.8 29.7 27.2 70.4 15.7 24.6 59.2 63.0 41.0 78.7 47.3 1.4 0.4 18.7 63.4 14.1 51.9 4.4 5.0 5.7 0.1 6.3 0.6 1.8 1.3 1.3 4.6 0.2 3.8 1.9 10.8 1.0 9.2 1.1 0.0 1.9 72.4 90.5 85.0 80.7 65.1 85.4 81.5 86.6 77.0 74.9 87.3 81.3 34.1 19.2 14.5 43.8 7.4 21.7 19.3 10.3 10.2 9.7 15.3 13.8 33.2 14.3 8.0 14.7 60.5 15.9 6.4 0.3 0.0 7.3 1.1 26.3 31.8 31.3 6.6 7.8 47.7 6.7 20.1 27.1 3.1 57.8 2.5 11.6 21.4 10.9 21.8 13.5 74.2 2.2 4.1 36.3 63.4 2.0 21.5 48.9 19.6 68.4 41.1 11.6 3.1 136.2 287.1 8.4 1.4 20.7 0.9 32.5 0.1 10.3 4.8 10.5 26.3 34.4 31.6 7.9 12.3 6.3 8.2 11.2 6.3 16.0 0.8 15.0 DENND6A "AFI1A, FAM116A, FLJ34969" ENSG00000174839 "DENN domain containing 6A" Q8IWF6 3 57625454-57693077 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 66.9;Inhibitory neurons: 65.4;Oligodendrocytes: 74.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 18.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 18.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062618, HPA069725, HPA071711" Approved Supported Vesicles NA NA "Cluster 34: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Vesicles "HPA062618: AB_2684809, HPA069725: AB_2686184, HPA071711: AB_2686435" "unprognostic (6.20e-2)" "unprognostic (3.86e-2)" "prognostic favorable (9.21e-4)" "unprognostic (1.76e-1)" "unprognostic (7.75e-2)" "unprognostic (3.17e-1)" "prognostic unfavorable (6.36e-4)" "unprognostic (7.16e-2)" "unprognostic (1.17e-2)" "unprognostic (2.28e-3)" "unprognostic (5.97e-3)" "unprognostic (1.12e-1)" "prognostic favorable (7.77e-6)" "unprognostic (3.06e-1)" "unprognostic (1.63e-1)" "unprognostic (3.61e-3)" "unprognostic (2.94e-1)" 11.6 7.3 3.4 8.8 4.6 12.6 12.9 12.9 7.1 11.8 3.8 10.7 7.1 12.7 9.9 11.4 10.3 8.3 8.0 3.0 5.5 8.9 7.7 10.5 12.6 4.2 4.8 20.9 5.3 11.4 6.6 11.8 5.3 9.9 9.2 10.0 8.4 11.7 7.1 8.6 9.2 11.3 4.7 12.9 9.7 8.0 4.7 11.8 14.0 9.8 10.5 10.7 10.5 8.4 16.8 13.5 18.0 11.0 9.4 10.6 10.2 8.6 11.0 10.5 8.2 8.7 18.4 19.9 3.6 8.9 9.2 8.8 14.4 18.2 8.9 5.1 12.9 15.7 15.1 6.7 9.0 12.1 8.9 11.3 13.0 7.2 18.7 10.6 15.2 21.1 10.8 21.1 7.6 7.3 26.2 14.9 10.2 10.6 9.3 10.9 10.7 14.8 12.8 28.1 6.1 22.0 17.1 13.9 12.5 7.7 9.1 14.7 16.7 12.7 6.8 13.6 22.8 15.7 22.2 20.7 14.8 19.9 18.9 18.7 1.0 1.4 2.4 1.1 2.9 0.8 2.3 2.4 1.3 1.2 3.4 2.6 1.5 1.9 1.4 1.0 1.3 1.0 3.4 4.6 12.9 7.1 3.0 5.5 4.2 4.8 5.3 4.7 4.7 8.4 28.8 19.2 8.2 31.3 14.5 12.9 11.8 10.6 12.0 16.2 9.9 9.1 20.8 11.5 10.0 5.5 8.4 6.4 21.4 5.7 3.9 8.1 22.2 10.1 25.6 16.0 3.0 16.2 66.9 10.9 4.4 15.7 10.2 17.1 2.5 24.1 20.7 11.1 11.1 10.1 65.4 5.5 12.2 34.3 9.9 11.3 11.8 16.8 3.6 47.8 16.8 10.2 20.6 42.3 74.3 18.9 3.5 14.3 9.5 8.4 6.5 8.9 8.0 14.5 6.6 19.2 18.3 13.3 5.0 14.1 10.7 2.3 19.6 16.7 6.1 13.0 DEPP1 "C10orf10, DEPP, FIG, Fseg" ENSG00000165507 "DEPP1 autophagy regulator" Q9NTK1 10 44970981-44978809 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 889.5;breast: 697.2" "Cell type enhanced" "Detected in many" "Adipocytes: 192.0;Ductal cells: 146.3;Exocrine glandular cells: 113.0;Glandular and luminal cells: 87.1;Syncytiotrophoblasts: 300.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 143.2;HDLM-2: 106.7;HHSteC: 258.2;HSkMC: 201.6;HUVEC TERT2: 165.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB013687, HPA037818, HPA037819" Uncertain Supported Vesicles,Mitochondria "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Mitochondria Vesicles "CAB013687: , HPA037818: , HPA037819: AB_2675685" "unprognostic (3.99e-2)" "unprognostic (4.69e-2)" "unprognostic (5.57e-2)" "unprognostic (3.55e-1)" "unprognostic (1.88e-2)" "unprognostic (5.66e-3)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (4.25e-1)" "unprognostic (5.53e-2)" "unprognostic (1.15e-1)" "unprognostic (8.89e-2)" "prognostic unfavorable (2.29e-6)" "unprognostic (2.30e-3)" "unprognostic (2.13e-1)" "unprognostic (5.42e-2)" "unprognostic (3.74e-1)" 889.5 48.4 62.3 19.4 71.4 4.5 697.2 59.5 71.8 153.0 50.3 145.7 16.7 168.5 16.5 65.7 334.2 68.5 260.6 55.5 71.9 95.4 131.6 508.6 63.0 175.9 72.3 297.8 349.7 23.0 85.2 76.5 93.4 82.6 12.0 28.2 119.7 22.8 165.8 165.0 94.8 68.8 101.6 32.8 104.6 19.3 87.4 25.2 200.5 52.2 47.6 177.6 139.1 90.6 30.2 0.2 0.5 0.4 143.2 69.5 7.4 0.2 10.2 0.4 1.8 1.1 11.2 0.0 1.6 13.5 7.1 1.2 1.2 9.1 0.7 106.7 4.0 0.1 0.1 11.0 258.2 0.1 0.1 201.6 0.4 0.1 1.4 24.9 165.0 0.0 0.2 63.2 0.6 0.0 0.1 1.7 0.2 0.6 0.9 5.1 1.7 25.7 0.5 10.9 5.6 0.3 0.0 1.3 5.8 17.0 0.2 7.0 1.6 7.8 5.6 0.5 7.3 1.7 2.8 0.4 44.2 2.6 4.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.0 0.0 0.4 62.3 71.4 59.5 71.8 55.5 71.9 175.9 72.3 93.4 101.6 87.4 90.6 192.0 0.0 24.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 47.0 27.8 0.0 0.0 6.2 31.3 0.0 53.8 1.4 0.0 37.2 146.3 0.0 61.3 33.2 60.0 0.0 0.0 0.0 113.0 14.7 79.3 0.0 87.1 0.0 8.4 0.0 0.0 25.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 22.7 0.0 0.0 0.0 0.0 65.0 0.0 0.0 0.5 0.0 0.0 25.5 5.8 0.0 0.0 0.0 38.5 0.0 0.0 0.0 0.0 300.2 1.8 0.8 0.0 0.0 DERL3 "C22orf14, derlin-3, FLJ43842, IZP6, MGC71803" ENSG00000099958 "Derlin 3" Q96Q80 22 23834503-23839128 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 61.6;pancreas: 60.8;salivary gland: 51.1" "Cell type enriched" "Detected in many" 6 "Plasma cells: 1428.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 14 "plasmacytoid DC: 187.4" "Lineage enriched" "Detected in many" 14 "dendritic cells: 187.4" "Cell line enhanced" "Detected in some" "Karpas-707: 26.9;RPMI-8226: 23.6;U-266/70: 48.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "CAB037234, HPA049306" Approved Uncertain Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "CAB037234: AB_1840802, HPA049306: " "unprognostic (2.01e-3)" "prognostic favorable (8.70e-5)" "unprognostic (9.72e-3)" "unprognostic (7.47e-2)" "unprognostic (9.77e-3)" "prognostic favorable (8.01e-4)" "unprognostic (2.23e-2)" "unprognostic (1.40e-1)" "unprognostic (1.36e-1)" "unprognostic (8.66e-3)" "unprognostic (4.74e-2)" "unprognostic (2.75e-1)" "prognostic unfavorable (7.76e-13)" "unprognostic (1.53e-2)" "unprognostic (4.08e-1)" "unprognostic (1.65e-1)" "unprognostic (1.95e-1)" 2.6 3.2 1.4 4.3 1.4 1.8 5.4 1.3 2.2 6.1 1.9 30.6 10.0 3.7 0.2 4.3 7.1 2.3 7.7 1.3 1.6 5.7 9.1 9.2 9.2 1.8 2.2 2.0 60.8 0.8 8.1 0.8 1.7 3.3 10.9 0.2 51.1 3.8 2.7 0.8 33.7 0.7 1.7 61.6 29.4 24.8 1.7 1.6 14.6 0.2 17.6 3.6 2.3 1.5 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 4.5 4.8 0.9 0.0 1.4 0.0 1.1 1.3 0.0 0.5 4.8 0.4 4.6 0.0 0.7 3.2 0.6 0.0 0.2 0.5 0.0 0.1 0.1 0.5 0.8 26.9 0.0 0.0 1.3 2.2 1.0 2.3 0.3 4.2 0.0 23.6 0.9 0.3 0.6 0.1 0.1 0.0 0.2 0.7 0.0 1.5 0.0 0.0 0.0 0.4 0.1 48.5 6.3 8.3 0.8 6.2 0.1 0.0 0.0 0.0 0.2 0.1 0.2 13.8 0.0 0.0 0.0 12.4 0.1 0.0 0.1 0.0 0.0 187.4 0.0 1.3 1.4 1.4 1.3 2.2 1.3 1.6 1.8 2.2 1.7 1.7 1.7 1.5 0.5 0.0 1.1 0.3 183.8 1.8 1.5 3.7 0.6 1.1 19.3 1.8 3.5 1.5 4.1 0.0 2.1 0.8 141.7 2.7 0.0 0.5 113.2 33.8 0.9 1.1 1.8 8.2 0.3 5.8 6.2 2.2 7.7 1.7 2.5 15.7 4.6 7.8 3.4 0.0 1.7 7.9 4.1 2.2 2.1 158.2 2.5 5.4 224.1 1.9 0.5 0.8 0.0 1.0 0.5 1.1 0.5 4.1 1428.8 2.5 0.8 0.5 30.3 0.6 0.0 0.8 2.6 67.0 32.9 1.3 2.0 15.5 17.9 2.1 10.7 2.0 DESI2 "C1orf121, CGI-146, DESI-2, FAM152A, FLJ21998, PNAS-4, PPPDE1" ENSG00000121644 "Desumoylating isopeptidase 2" Q9BSY9 1 244653103-244709033 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 171.8;Spermatocytes: 192.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049950 Approved Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA049950: AB_2680969" "unprognostic (1.13e-1)" "unprognostic (2.07e-1)" "unprognostic (1.05e-1)" "unprognostic (3.09e-1)" "unprognostic (1.96e-1)" "unprognostic (5.40e-2)" "unprognostic (1.95e-2)" "unprognostic (7.62e-2)" "unprognostic (1.38e-3)" "unprognostic (1.51e-1)" "unprognostic (4.47e-3)" "unprognostic (1.45e-1)" "prognostic unfavorable (4.25e-5)" "unprognostic (4.52e-2)" "unprognostic (8.27e-2)" "unprognostic (2.27e-2)" "unprognostic (9.49e-2)" 17.1 13.6 7.7 13.6 10.7 17.1 14.0 13.0 8.4 18.4 13.1 16.4 16.0 22.7 13.6 16.2 13.3 17.8 16.4 7.4 7.9 11.8 12.8 23.2 17.9 7.7 8.0 13.6 9.3 13.9 7.1 18.6 7.4 14.4 18.2 16.2 11.1 15.6 24.1 15.2 13.3 22.3 8.1 11.7 15.6 54.8 8.3 19.7 23.3 23.6 19.1 18.4 12.0 8.1 68.1 24.3 47.0 40.8 52.8 54.8 61.7 40.8 65.9 36.9 33.9 43.8 31.0 121.8 53.8 47.7 21.5 29.5 58.1 43.1 50.5 43.1 53.6 31.0 17.5 33.0 46.2 52.8 36.1 38.4 57.3 49.3 61.6 35.6 52.8 52.8 48.4 63.7 56.2 11.7 49.6 28.0 109.0 62.7 67.7 36.9 71.9 46.0 28.4 27.6 42.5 57.2 55.4 26.4 47.7 37.7 27.6 39.0 59.7 41.7 45.4 57.4 68.5 69.4 94.1 69.8 33.8 55.7 78.0 2.5 1.7 5.6 2.1 2.1 2.1 5.2 2.2 3.0 2.7 2.7 2.9 2.8 1.4 2.2 2.3 2.4 3.2 0.7 7.7 10.7 13.0 8.4 7.4 7.9 7.7 8.0 7.4 8.1 8.3 8.1 32.7 86.6 60.4 17.9 31.0 55.3 41.3 23.0 38.7 43.2 21.5 26.3 22.1 27.1 25.5 18.4 20.9 29.8 36.1 28.1 21.5 19.8 171.8 32.0 39.6 36.2 15.6 21.7 18.4 33.4 40.0 44.2 28.5 25.0 7.0 28.7 25.7 21.5 23.8 40.4 23.1 19.0 26.4 23.3 27.1 101.5 34.8 27.2 16.0 18.7 25.5 23.8 28.8 35.7 26.9 34.3 28.6 51.9 34.5 69.5 17.0 16.5 17.6 25.1 39.5 41.7 50.2 192.7 105.4 42.4 41.3 43.2 31.2 38.4 25.4 55.5 DGAT2 ENSG00000062282 "Diacylglycerol O-acyltransferase 2" Q96PD7 11 75759512-75801535 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 476.0;breast: 133.6;liver: 331.8;skin 1: 151.5" "Cell type enhanced" "Detected in many" "Early spermatids: 259.3;Hepatocytes: 116.4;Late spermatids: 64.1;Spermatocytes: 53.9;Spermatogonia: 53.5" "Cancer enhanced" "Detected in many" "liver cancer: 19.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "eosinophil: 137.7;neutrophil: 348.6" "Lineage enriched" "Detected in many" 16 "granulocytes: 348.6" "Cell line enhanced" "Detected in many" "ASC diff: 80.4;HDLM-2: 62.5;Hep G2: 64.9;OE19: 124.0" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "basal ganglia: 22.0" HPA013351 Approved Vesicles,Cytosol NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 21: OE19 - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "Vesicles, Cytosol" "HPA013351: AB_1847630" "unprognostic (2.28e-1)" "unprognostic (3.69e-1)" "unprognostic (9.38e-2)" "prognostic unfavorable (2.84e-4)" "unprognostic (3.63e-1)" "unprognostic (4.99e-2)" "unprognostic (1.10e-2)" "unprognostic (7.59e-2)" "unprognostic (4.46e-1)" "unprognostic (4.12e-3)" "unprognostic (2.87e-1)" "unprognostic (2.99e-1)" "unprognostic (1.49e-7)" "unprognostic (2.03e-1)" "unprognostic (2.85e-1)" "unprognostic (2.74e-2)" "unprognostic (5.60e-2)" 476.0 5.1 5.8 19.4 11.7 7.2 133.6 2.9 6.1 2.6 5.3 9.0 14.5 1.2 1.8 24.1 2.1 5.8 11.7 5.7 6.4 3.4 331.8 5.6 4.0 3.7 3.9 1.8 4.6 2.1 1.6 1.5 5.5 2.2 4.9 0.6 10.5 1.6 4.1 151.5 16.5 2.8 3.4 15.0 12.8 38.1 6.9 4.3 8.8 5.6 18.2 21.3 12.6 5.1 13.3 6.4 0.4 11.2 80.4 6.4 1.0 1.3 1.7 1.6 1.0 46.6 13.5 21.1 16.8 0.3 11.9 0.5 1.8 6.5 4.4 62.5 1.2 1.5 4.0 64.9 0.9 7.4 7.2 26.8 33.6 7.3 10.6 4.4 1.2 20.9 1.2 27.6 0.7 8.5 5.1 16.7 3.6 124.0 31.5 0.0 0.1 24.8 1.2 35.8 22.6 1.4 12.3 1.9 2.9 2.7 4.4 26.6 1.6 14.1 7.0 0.3 9.1 16.3 40.0 28.8 10.2 23.7 25.3 19.4 22.1 137.7 0.0 4.4 0.4 7.4 0.4 0.0 6.1 7.6 0.1 0.2 348.6 0.0 5.0 1.8 0.0 5.7 5.8 11.7 2.9 6.1 5.7 6.4 3.7 3.9 5.5 3.4 6.9 5.1 3.2 6.4 5.4 0.3 5.0 1.1 0.9 3.0 0.6 0.9 5.2 7.0 3.5 0.0 2.7 0.0 2.1 0.5 0.3 0.6 0.0 1.7 259.3 3.3 0.2 0.5 1.2 2.7 2.9 0.5 0.1 0.7 10.7 0.2 0.0 2.1 2.9 116.4 2.2 1.7 1.3 4.8 0.0 4.1 13.1 64.1 2.1 4.2 1.8 0.0 4.0 0.4 0.0 0.0 1.0 3.7 2.2 0.7 0.9 2.8 1.2 2.2 3.4 0.0 6.6 0.6 1.0 53.9 53.5 0.3 8.0 0.8 0.5 0.2 3.0 15.7 DGKA "DAGK, DAGK1, DGK-alpha" ENSG00000065357 "Diacylglycerol kinase alpha" P23743 12 55927319-55954027 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 101.5;lymphoid tissue: 198.1" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 49.0;Squamous epithelial cells: 40.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "T-cells: 86.9" "Cell line enhanced" "Detected in many" "HBEC3-KT: 130.4;hTERT-HME1: 133.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041645, HPA045462" Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 58: T-cells - T-cell receptor" Vesicles "Nucleoplasm, Mitochondria" "HPA041645: AB_2677595, HPA045462: AB_2679335" "unprognostic (1.12e-3)" "unprognostic (1.43e-2)" "unprognostic (1.62e-2)" "unprognostic (2.63e-2)" "unprognostic (5.23e-2)" "unprognostic (2.04e-1)" "unprognostic (3.62e-1)" "unprognostic (3.31e-2)" "unprognostic (5.28e-2)" "unprognostic (1.94e-1)" "unprognostic (1.82e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (1.66e-5)" "unprognostic (4.06e-1)" "unprognostic (1.00e-1)" "unprognostic (1.47e-1)" "unprognostic (7.02e-2)" 12.7 12.8 7.6 50.0 9.8 31.9 11.0 6.6 9.2 22.9 7.0 25.6 51.2 13.1 9.9 101.5 11.4 15.8 8.5 7.2 5.2 7.9 3.7 18.6 95.5 5.2 5.0 10.9 14.6 12.0 6.9 14.9 5.3 24.8 26.9 2.8 35.5 9.6 2.3 84.7 64.8 14.1 4.8 53.8 12.4 12.3 5.0 198.1 10.5 4.2 101.8 28.4 39.0 6.8 22.2 13.2 9.3 12.4 22.4 29.0 2.8 47.2 47.8 18.2 13.5 6.9 35.2 13.5 11.1 31.5 6.2 38.7 10.3 130.4 21.4 14.4 2.5 21.1 26.8 3.6 19.1 6.7 20.9 25.1 68.4 25.2 133.9 60.6 37.9 78.8 2.4 18.7 49.4 2.3 54.3 8.6 2.0 18.1 15.5 23.8 2.9 2.0 43.7 60.9 1.6 5.6 15.5 0.9 1.7 23.8 9.3 6.4 34.0 12.0 8.4 2.8 1.7 2.9 1.2 32.4 13.8 17.5 3.4 17.0 7.4 15.3 18.5 5.2 35.5 20.4 70.6 33.0 10.5 16.2 86.9 51.5 13.3 14.1 3.5 10.5 86.7 36.2 7.6 9.8 6.6 9.2 7.2 5.2 5.2 5.0 5.3 4.8 5.0 6.8 4.5 3.2 6.5 1.6 25.7 15.0 9.7 21.1 26.7 1.2 4.0 4.6 2.9 4.3 19.1 5.5 0.0 16.3 12.2 35.4 0.0 5.1 9.4 1.9 6.5 5.3 2.4 11.2 11.2 9.4 4.3 8.2 15.3 3.0 7.0 2.4 4.2 0.2 4.2 0.0 5.2 7.7 2.0 6.9 21.6 7.0 3.7 14.0 0.0 5.6 15.7 2.6 10.3 9.0 0.8 25.3 14.4 3.0 14.8 8.2 49.0 0.3 5.2 0.5 6.6 1.5 4.2 6.6 4.2 40.4 13.9 26.4 37.4 1.6 9.7 20.1 DGKG DAGK3 ENSG00000058866 "Diacylglycerol kinase gamma" P49619 3 186105668-186362234 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.2" "Cell type enhanced" "Detected in many" "Astrocytes: 223.0;Excitatory neurons: 111.0;Inhibitory neurons: 63.5;Oligodendrocyte precursor cells: 334.8" "Cancer enhanced" "Detected in some" "glioma: 2.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "classical monocyte: 2.1;eosinophil: 1.2;intermediate monocyte: 1.2;myeloid DC: 1.5;neutrophil: 2.6;non-classical monocyte: 1.5" "Group enriched" "Detected in many" 7 "dendritic cells: 1.5;granulocytes: 2.6;monocytes: 2.1" "Cell line enhanced" "Detected in some" "HDLM-2: 23.9;HL-60: 7.7;U-266/84: 9.4;U-87 MG: 14.3;U-937: 7.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036577 Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 6: Brain - Smell perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Plasma membrane" "HPA036577: AB_10672358" "unprognostic (2.23e-1)" "unprognostic (1.97e-1)" "unprognostic (1.56e-2)" "unprognostic (3.24e-5)" "unprognostic (2.70e-1)" "unprognostic (6.09e-4)" "unprognostic (1.21e-3)" "unprognostic (3.80e-2)" "unprognostic (5.88e-2)" "unprognostic (1.50e-1)" "unprognostic (1.94e-1)" "unprognostic (5.09e-2)" "unprognostic (8.05e-7)" "unprognostic (3.47e-3)" "unprognostic (7.19e-2)" "unprognostic (1.41e-1)" "unprognostic (9.16e-3)" 1.6 4.2 14.2 0.8 17.4 9.3 1.1 28.2 11.9 2.2 0.0 3.2 1.4 1.2 8.0 4.6 4.1 0.9 9.1 20.4 3.6 1.3 0.8 3.8 0.9 20.1 6.5 1.2 0.5 5.7 6.0 7.8 20.8 1.3 0.8 1.7 0.8 1.8 1.8 0.8 1.7 2.4 0.6 0.9 2.1 0.3 9.6 0.5 1.8 1.0 0.8 3.4 1.7 13.2 3.2 4.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 2.7 0.0 3.3 0.2 0.0 0.0 0.0 23.9 0.0 3.2 0.0 3.5 0.0 7.7 0.3 0.0 0.0 1.4 0.0 0.1 0.0 0.6 0.0 0.4 0.4 0.1 0.1 2.6 0.4 0.0 1.4 1.7 0.0 2.6 0.0 0.0 0.6 0.0 0.9 0.0 2.0 0.0 0.1 4.9 0.0 0.0 0.8 2.4 2.9 0.0 9.4 0.0 14.3 7.0 2.6 0.0 2.1 1.2 0.0 1.2 0.0 0.3 0.0 0.0 1.5 0.1 0.0 0.0 2.6 0.0 1.5 0.2 0.0 0.7 14.2 17.4 28.2 11.9 20.4 3.6 20.1 6.5 20.8 0.6 9.6 13.2 0.1 0.0 1.7 223.0 3.1 0.4 0.2 0.0 0.6 0.1 0.1 0.4 19.4 1.5 0.0 1.8 0.0 0.1 0.0 0.0 0.0 1.4 2.6 0.3 0.1 5.0 0.0 0.4 111.0 1.2 0.0 0.5 0.5 0.1 0.0 0.3 22.1 0.0 2.1 1.7 63.5 0.1 0.0 3.2 1.4 4.2 1.8 3.4 0.0 12.2 5.2 6.8 0.0 334.8 7.8 1.0 0.1 0.4 0.2 0.4 0.1 0.9 0.0 0.1 13.1 1.8 14.5 0.0 0.2 0.4 0.4 0.1 0.1 0.9 0.1 0.4 DGKH DGKeta ENSG00000102780 "Diacylglycerol kinase eta" Q86XP1 13 42040036-42256578 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.8" "Cell type enhanced" "Detected in all" "Prostatic glandular cells: 137.8;Urothelial cells: 147.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 25.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039533, HPA040355, HPA061538" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 10: Brain - Neuronal signaling" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Vesicles "HPA039533: AB_10795145, HPA040355: AB_10796452, HPA061538: " "unprognostic (2.80e-1)" "unprognostic (7.03e-2)" "unprognostic (1.30e-1)" "unprognostic (5.69e-2)" "unprognostic (1.55e-3)" "unprognostic (7.62e-2)" "unprognostic (1.04e-2)" "unprognostic (9.60e-2)" "unprognostic (7.00e-3)" "unprognostic (4.37e-2)" "unprognostic (1.86e-1)" "unprognostic (2.41e-1)" "unprognostic (3.43e-3)" "unprognostic (1.03e-1)" "unprognostic (1.67e-1)" "unprognostic (4.93e-2)" "unprognostic (1.43e-2)" 3.7 1.3 4.5 2.0 25.8 1.3 3.5 8.7 5.4 4.4 0.0 3.7 1.5 6.4 6.9 4.1 4.3 2.5 3.0 7.3 4.4 3.3 1.0 7.8 2.2 0.0 7.4 2.8 1.0 0.7 2.6 4.5 0.4 2.8 3.3 2.6 3.0 2.1 1.5 3.2 2.7 4.0 0.2 1.7 2.6 2.3 9.7 2.7 2.5 2.2 1.3 5.3 4.6 2.8 5.6 6.6 4.3 3.6 1.9 4.2 0.5 3.4 2.7 2.2 2.8 0.6 4.7 4.3 4.1 3.7 8.3 11.8 3.8 7.7 3.3 3.4 12.4 7.6 3.6 0.4 2.4 3.3 2.0 1.6 7.7 4.3 17.0 3.4 9.9 5.3 3.0 2.9 3.8 5.1 3.4 1.7 1.9 5.2 4.3 5.0 3.8 2.9 7.4 16.7 2.5 2.6 3.1 4.0 3.0 1.8 3.4 8.9 9.8 4.1 3.8 4.5 4.7 1.5 1.5 4.8 2.4 2.9 3.1 0.6 0.3 0.1 0.2 0.2 0.2 0.1 0.4 0.4 0.0 0.2 0.2 0.4 0.9 0.1 0.1 0.3 0.3 0.1 4.5 25.8 8.7 5.4 7.3 4.4 0.0 7.4 0.4 0.2 9.7 2.8 64.8 22.4 20.1 8.8 1.9 61.7 58.1 61.1 15.9 44.5 13.6 8.9 8.5 24.3 44.7 11.0 4.2 3.7 2.2 29.0 1.9 11.3 25.9 64.1 26.0 50.8 47.4 2.7 85.4 7.2 2.2 17.5 15.3 46.2 7.6 5.7 23.2 3.2 6.8 1.7 60.2 18.7 14.2 5.6 43.1 20.1 3.4 8.0 8.8 56.2 8.6 18.8 1.0 54.3 11.0 27.6 19.2 9.1 6.2 137.8 13.1 8.4 91.8 2.6 26.3 16.2 54.1 3.8 3.8 19.7 33.1 2.9 13.0 11.5 22.0 147.3 DHRS12 "FLJ13639, SDR40C1" ENSG00000102796 "Dehydrogenase/reductase 12" A0PJE2 13 51767993-51804162 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "pancreas: 66.8" "Cell type enhanced" "Detected in many" "Late spermatids: 69.1;Proximal tubular cells: 83.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "CAB034238, HPA057028, HPA058315" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Golgi apparatus, Vesicles" "CAB034238: AB_2091845, HPA057028: AB_2683314, HPA058315: AB_2683678" "prognostic favorable (1.41e-4)" "unprognostic (1.98e-2)" "unprognostic (2.98e-1)" "unprognostic (7.57e-2)" "unprognostic (2.98e-1)" "unprognostic (1.42e-1)" "unprognostic (8.47e-3)" "unprognostic (1.70e-1)" "unprognostic (3.51e-1)" "unprognostic (3.99e-2)" "unprognostic (1.21e-2)" "unprognostic (3.98e-1)" "prognostic favorable (2.22e-16)" "unprognostic (2.85e-3)" "unprognostic (1.01e-1)" "unprognostic (2.03e-2)" "unprognostic (3.44e-1)" 22.7 10.6 7.8 2.9 7.3 4.5 20.5 8.9 7.8 13.9 6.5 14.0 5.5 13.1 5.0 10.3 14.5 6.1 14.3 7.3 6.7 24.6 28.9 11.7 5.3 7.2 6.6 18.4 66.8 6.6 18.7 3.6 7.0 15.4 3.7 5.9 15.0 5.9 16.0 14.1 12.5 4.0 7.6 15.7 15.0 8.2 7.0 2.3 18.8 4.1 3.5 13.2 11.2 8.3 1.1 2.5 3.8 5.6 1.2 2.6 4.4 1.6 4.1 1.8 1.3 4.5 8.6 4.2 1.2 2.5 2.5 2.0 0.0 0.3 0.3 4.2 3.4 0.6 1.1 3.2 6.6 0.4 0.7 2.7 3.9 0.6 2.4 4.5 5.2 4.0 2.0 3.0 1.3 5.5 1.0 3.5 6.1 4.2 0.6 0.5 0.8 5.8 5.6 3.2 3.4 6.9 2.9 2.5 7.1 5.0 2.8 2.8 3.7 1.3 1.5 0.1 1.7 1.4 1.8 1.9 2.3 1.4 3.7 6.6 16.6 0.5 14.0 14.2 24.1 13.7 19.7 16.9 9.0 13.4 16.4 12.9 31.4 3.8 16.5 10.6 19.8 13.5 7.8 7.3 8.9 7.8 7.3 6.7 7.2 6.6 7.0 7.6 7.0 8.3 14.1 12.8 14.8 11.1 11.4 11.3 12.1 22.2 10.8 11.9 23.5 22.9 15.7 18.6 13.3 16.5 8.4 24.9 8.0 7.8 52.8 12.5 26.1 5.6 7.7 10.1 10.3 2.1 4.9 16.7 17.5 17.1 7.1 6.4 12.0 6.8 8.6 30.7 17.1 3.3 5.4 12.4 22.4 11.2 11.6 69.1 11.1 10.1 14.2 3.7 10.5 32.4 8.2 24.6 12.9 12.6 21.9 9.8 4.8 12.2 25.5 83.5 19.5 18.5 0.0 14.2 11.4 1.4 8.2 10.5 14.9 23.8 13.7 13.4 11.0 12.2 DHRS13 "MGC23280, SDR7C5" ENSG00000167536 "Dehydrogenase/reductase 13" Q6UX07 17 28897781-28903079 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 41.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 55.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 55.3" "Cell line enhanced" "Detected in all" "SK-BR-3: 69.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA022991 Uncertain Approved Vesicles "Secreted - unknown location" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "HPA022991: AB_1853865" "unprognostic (8.87e-2)" "unprognostic (1.64e-1)" "unprognostic (1.91e-1)" "unprognostic (2.35e-1)" "unprognostic (1.21e-2)" "unprognostic (6.37e-2)" "prognostic unfavorable (3.39e-6)" "unprognostic (2.38e-1)" "unprognostic (4.74e-2)" "unprognostic (5.65e-2)" "unprognostic (1.20e-2)" "unprognostic (7.57e-2)" "unprognostic (1.73e-2)" "unprognostic (3.72e-2)" "unprognostic (2.63e-1)" "unprognostic (7.22e-3)" "unprognostic (2.55e-1)" 3.1 7.0 9.9 5.7 8.6 41.8 5.4 17.1 9.6 6.4 11.8 4.8 4.4 3.0 6.6 8.8 4.1 2.9 2.8 8.6 15.3 12.2 23.6 4.7 6.6 13.0 14.9 3.5 6.6 7.9 6.3 4.5 14.0 19.4 3.6 8.3 12.7 10.6 1.3 7.4 4.0 2.2 10.1 10.2 5.9 3.0 13.0 4.6 4.7 2.3 6.9 9.5 6.3 9.5 12.1 7.6 17.4 22.2 2.6 3.8 16.8 6.4 8.3 11.6 17.7 23.5 7.1 32.8 10.7 1.4 13.4 10.5 24.8 7.1 4.9 33.5 23.9 18.4 13.9 13.0 6.5 9.5 2.1 2.8 6.3 7.3 7.7 8.1 3.6 22.7 42.3 11.0 2.3 21.7 20.9 15.9 10.7 31.4 1.0 32.8 16.4 25.5 21.8 20.2 24.8 20.8 10.1 69.5 13.9 9.1 46.4 15.2 1.2 3.7 11.1 9.0 8.9 25.5 25.7 20.7 11.0 11.9 9.4 0.9 4.4 3.1 8.5 6.9 10.4 7.1 10.8 10.7 5.9 8.6 10.9 8.1 55.3 9.4 6.8 3.2 11.4 5.8 9.9 8.6 17.1 9.6 8.6 15.3 13.0 14.9 14.0 10.1 13.0 9.5 2.4 3.2 4.2 2.3 6.7 1.5 10.2 12.3 12.0 6.1 7.1 5.7 0.4 8.6 5.4 7.3 2.1 27.7 4.4 4.3 9.8 10.6 11.9 3.4 1.1 4.5 3.0 106.1 0.7 2.7 22.2 2.1 7.7 6.3 1.3 1.2 6.4 5.5 6.2 5.0 4.4 4.2 2.0 0.8 3.0 5.2 1.2 2.1 5.4 1.0 15.5 8.2 10.3 3.0 1.0 2.5 2.4 0.4 12.8 11.5 2.8 3.2 2.2 5.0 6.6 0.9 1.1 6.1 22.5 9.4 1.7 13.5 7.0 0.5 6.4 5.8 DHRS4 "FLJ11008, humNRDR, SCAD-SRL, SDR-SRL, SDR25C2" ENSG00000157326 "Dehydrogenase/reductase 4" Q9BTZ2 14 23953734-23969279 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 235.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA023972 Uncertain Approved "Nuclear membrane,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "Nuclear membrane" "HPA023972: AB_1854890" "unprognostic (1.21e-2)" "unprognostic (2.59e-1)" "unprognostic (3.46e-2)" "unprognostic (3.79e-3)" "unprognostic (1.97e-1)" "unprognostic (1.66e-1)" "unprognostic (7.35e-3)" "unprognostic (1.61e-3)" "unprognostic (2.66e-1)" "unprognostic (1.19e-2)" "unprognostic (1.06e-2)" "unprognostic (7.65e-2)" "prognostic favorable (4.55e-6)" "unprognostic (2.03e-2)" "unprognostic (1.48e-1)" "unprognostic (2.03e-1)" "unprognostic (5.68e-2)" 34.1 45.8 8.6 10.4 9.2 6.9 34.5 8.8 9.7 30.5 10.1 43.5 34.0 27.1 5.2 45.8 23.6 5.9 49.1 8.3 8.6 92.0 109.7 28.0 10.2 9.2 8.6 33.0 40.3 8.8 19.3 5.3 9.2 31.9 13.5 3.9 31.2 8.4 62.2 44.7 38.6 8.3 8.6 32.2 33.7 37.9 9.0 9.6 25.4 14.0 8.5 30.5 33.1 9.5 15.1 29.6 10.4 17.2 16.6 18.5 0.1 27.4 15.3 11.5 9.1 6.5 16.5 13.3 14.3 14.6 7.6 18.1 8.6 12.3 10.1 34.6 16.5 7.8 23.5 36.6 9.5 11.6 45.2 18.0 14.8 9.2 20.8 12.3 14.4 19.6 11.8 30.4 15.8 52.3 21.1 10.7 9.9 18.9 30.3 33.8 18.0 41.4 12.1 17.1 19.9 16.1 27.7 17.6 13.8 6.8 16.0 14.6 25.5 13.3 13.8 13.9 9.0 22.8 22.8 3.5 11.8 12.6 13.6 5.4 54.4 6.0 18.0 45.8 21.4 21.5 20.3 18.2 47.4 18.5 20.1 19.5 2.3 18.1 25.5 39.4 19.4 36.2 8.6 9.2 8.8 9.7 8.3 8.6 9.2 8.6 9.2 8.6 9.0 9.5 16.6 16.0 30.5 6.2 12.5 12.5 10.4 15.7 55.2 5.1 22.2 31.9 35.4 17.2 21.3 14.7 0.0 9.6 17.8 34.2 78.2 6.4 50.4 13.1 11.6 14.6 19.2 20.8 2.6 9.8 6.0 23.7 34.7 7.8 13.9 10.5 20.0 68.1 30.4 6.7 2.1 50.1 8.2 29.2 13.5 66.1 11.1 35.9 5.4 3.7 33.2 18.1 47.4 4.0 5.0 5.3 22.3 17.3 24.6 11.2 51.8 235.4 23.2 1.8 6.6 13.5 18.1 59.4 1.9 61.6 13.4 3.8 18.1 22.9 71.8 9.0 DHRS4L2 SDR25C3 ENSG00000187630 "Dehydrogenase/reductase 4 like 2" Q6PKH6 14 23969874-24006408 "Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 136.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 204.2;Proximal enterocytes: 326.4;Proximal tubular cells: 581.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA023972 Uncertain Approved "Nuclear membrane,Vesicles" "Secreted - unknown location" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "Nuclear membrane" "HPA023972: AB_1854890" "unprognostic (1.41e-2)" "unprognostic (2.83e-3)" "unprognostic (1.25e-1)" "unprognostic (2.68e-2)" "unprognostic (1.47e-1)" "unprognostic (2.53e-1)" "unprognostic (6.02e-2)" "unprognostic (3.97e-3)" "unprognostic (7.34e-2)" "prognostic favorable (3.21e-4)" "unprognostic (1.57e-2)" "unprognostic (1.46e-2)" "unprognostic (1.36e-3)" "unprognostic (6.00e-2)" "unprognostic (2.38e-1)" "unprognostic (2.00e-1)" "unprognostic (3.65e-2)" 27.2 39.5 28.8 14.6 29.6 11.5 30.5 28.3 38.4 26.9 30.8 34.7 34.4 19.7 12.8 38.4 18.6 10.6 45.9 28.5 27.8 122.5 136.2 22.5 14.6 29.3 28.7 25.2 34.0 24.5 16.7 10.0 28.7 32.5 26.6 6.7 24.7 20.7 50.7 37.1 42.0 18.4 28.6 29.3 27.9 41.4 29.4 16.9 21.5 28.5 16.5 26.0 26.1 29.9 18.7 29.0 4.9 24.4 46.2 47.9 0.6 17.3 34.3 24.8 18.4 8.4 22.5 12.6 11.5 35.3 16.0 20.6 22.3 29.1 20.6 43.3 13.3 3.1 24.8 52.4 34.0 15.3 47.9 50.0 36.4 16.3 23.7 17.0 29.5 40.0 10.1 44.9 26.7 61.5 40.4 16.5 9.7 45.9 31.8 64.9 19.9 38.2 35.6 23.7 26.0 15.7 24.5 21.5 15.0 10.3 25.2 24.5 20.8 12.9 13.4 15.4 8.8 25.5 21.1 3.8 11.1 23.7 18.8 4.8 56.3 6.9 19.4 47.2 20.1 21.9 20.9 22.2 45.4 17.4 21.0 19.1 2.6 17.2 29.3 37.4 21.8 33.6 28.8 29.6 28.3 38.4 28.5 27.8 29.3 28.7 28.7 28.6 29.4 29.9 39.3 16.0 29.6 10.4 17.8 27.8 46.1 56.8 27.9 9.9 45.5 54.4 17.2 47.1 34.3 25.8 2.1 21.2 22.9 37.9 127.2 40.0 20.7 20.6 20.1 32.0 37.3 24.2 7.3 55.7 7.3 36.4 13.3 16.5 17.7 31.8 50.0 204.2 146.1 11.8 6.7 61.7 42.7 55.9 42.8 35.4 43.8 41.9 51.6 10.3 65.0 79.5 35.0 10.1 8.5 30.4 54.9 37.2 10.8 32.5 326.4 581.7 28.6 8.3 32.9 24.2 32.7 17.2 1.7 42.1 40.2 13.0 21.3 37.5 78.1 42.4 DIAPH2 "DIA, DIA2, POF, POF2" ENSG00000147202 "Diaphanous related formin 2" O60879 X 96684663-97604997 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Oogenesis" "Developmental protein" "Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 171.0;Late spermatids: 177.8;Microglial cells: 301.7;Oligodendrocyte precursor cells: 281.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005647, CAB015461, CAB068183, CAB068184" Enhanced Supported "Nucleoli,Endoplasmic reticulum,Vesicles" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 32: U-937 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Endoplasmic reticulum, Vesicles" Nucleoli "CAB015461: AB_831223, CAB068183: AB_2665693, CAB068184: AB_2665694, HPA005647: AB_1078657" "unprognostic (5.75e-2)" "unprognostic (4.13e-3)" "unprognostic (1.48e-1)" "prognostic unfavorable (2.16e-5)" "unprognostic (1.58e-1)" "unprognostic (6.48e-2)" "unprognostic (4.06e-1)" "unprognostic (1.07e-2)" "unprognostic (2.41e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (2.12e-4)" "unprognostic (3.39e-2)" "prognostic unfavorable (3.90e-4)" "unprognostic (6.44e-2)" "unprognostic (3.11e-2)" "unprognostic (6.99e-3)" "unprognostic (6.08e-3)" 10.7 3.3 3.7 6.4 6.4 17.7 7.0 0.0 4.3 10.6 17.3 8.6 4.3 5.5 3.5 7.7 6.7 5.7 5.4 6.4 3.1 3.1 12.3 8.2 3.8 0.6 0.9 7.7 4.9 7.0 2.0 12.5 1.0 6.1 8.7 3.0 6.6 7.6 12.0 5.3 5.3 7.4 0.2 3.8 7.4 9.4 1.5 6.0 3.9 9.1 3.9 7.4 9.8 1.8 0.0 6.5 3.1 6.3 17.1 28.3 0.0 11.2 11.8 5.9 12.4 5.5 12.3 18.5 8.7 9.7 11.3 0.0 16.6 1.7 7.6 0.5 9.5 0.0 7.4 5.9 14.2 24.3 8.2 14.3 6.0 8.0 24.6 8.0 11.6 13.6 0.0 14.9 11.2 5.3 9.2 10.0 24.4 0.1 9.4 0.0 16.5 0.0 3.4 9.8 0.0 6.3 0.0 3.2 9.0 18.8 2.7 13.2 14.8 12.6 5.8 10.6 7.3 0.2 0.0 15.3 10.7 24.1 7.6 0.0 3.1 3.3 1.1 2.8 0.9 1.7 1.2 1.4 2.3 1.3 0.8 0.7 0.3 0.7 2.5 2.2 0.7 0.6 3.7 6.4 0.0 4.3 6.4 3.1 0.6 0.9 1.0 0.2 1.5 1.8 61.7 32.1 51.1 21.2 18.8 10.8 6.8 11.9 11.4 5.5 9.9 8.1 20.2 15.7 15.0 20.2 0.0 65.2 21.5 36.6 7.9 18.6 80.5 51.2 46.2 31.2 24.6 6.1 171.0 23.4 16.8 35.2 41.8 41.7 7.6 36.1 8.2 26.1 21.0 0.0 90.0 32.3 4.1 29.6 19.3 177.8 45.1 34.7 8.8 301.7 32.7 13.0 10.3 281.0 41.2 38.4 39.3 20.3 11.6 8.0 11.9 9.4 57.1 13.7 26.3 46.7 32.7 7.5 12.9 17.6 18.3 118.3 19.0 19.0 32.5 6.0 DIDO1 "BYE1, C20orf158, DATF1, DIO-1, DIO1, dJ885L7.8, FLJ11265, KIAA0333" ENSG00000101191 "Death inducer-obliterator 1" Q9BTC0 20 62877738-62937952 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004374, HPA049904" Supported Approved Nucleoplasm,Vesicles,Cytosol No No "Cluster 10: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Vesicles, Cytosol" "CAB004374: AB_2093108, HPA049904: AB_2680944" "unprognostic (9.56e-3)" "unprognostic (2.62e-1)" "unprognostic (1.80e-1)" "unprognostic (7.47e-2)" "unprognostic (2.68e-1)" "prognostic favorable (5.13e-4)" "unprognostic (9.92e-3)" "unprognostic (4.57e-3)" "unprognostic (2.54e-2)" "unprognostic (2.06e-1)" "prognostic favorable (3.88e-4)" "unprognostic (2.20e-2)" "unprognostic (1.50e-3)" "unprognostic (1.06e-1)" "unprognostic (5.64e-2)" "unprognostic (8.90e-2)" "unprognostic (9.82e-2)" 30.4 20.1 15.7 21.5 17.6 29.1 31.0 22.4 17.8 33.8 23.3 36.3 19.6 38.2 26.8 27.1 36.8 17.5 27.6 15.4 17.2 25.5 24.7 30.9 31.6 16.4 16.4 39.5 24.6 28.5 28.1 24.8 16.6 34.0 19.7 19.9 33.2 24.9 32.5 39.5 36.5 20.9 14.0 35.9 28.8 27.9 17.3 30.8 33.0 22.8 26.9 32.6 31.5 22.2 29.6 22.5 36.7 21.0 18.4 22.6 19.6 21.9 18.5 79.4 22.8 96.4 29.9 29.0 29.4 26.9 46.1 45.2 33.8 42.4 51.1 16.1 22.9 41.9 40.2 69.6 23.5 37.8 41.6 23.3 57.0 27.5 15.4 18.1 22.1 54.6 41.7 25.8 20.5 28.7 76.9 33.1 29.4 35.7 32.2 53.7 47.0 18.5 13.1 26.0 45.2 26.7 43.8 41.9 28.9 21.9 41.8 42.7 27.8 64.3 44.8 21.7 31.5 17.1 11.9 38.2 29.3 18.8 23.7 32.6 7.2 20.2 15.0 9.5 15.9 11.7 13.4 14.8 5.1 9.8 17.6 16.5 10.6 13.8 7.6 10.7 11.8 9.6 15.7 17.6 22.4 17.8 15.4 17.2 16.4 16.4 16.6 14.0 17.3 22.2 24.8 25.6 30.1 37.9 28.4 24.2 35.3 17.8 25.6 25.6 23.1 19.6 27.5 22.8 23.8 25.8 33.3 28.6 49.0 32.3 23.5 18.0 42.8 32.1 26.1 26.2 19.2 21.0 44.9 13.8 15.7 24.2 30.1 34.3 22.8 33.8 20.7 19.6 14.5 38.7 46.0 23.2 14.2 16.8 13.7 13.0 35.1 20.2 21.4 32.8 26.8 16.7 42.2 40.7 47.4 22.2 20.2 33.8 30.0 26.3 25.3 9.6 45.8 23.4 6.6 35.4 23.4 26.1 32.1 26.0 25.6 19.7 32.1 25.6 21.1 34.4 DIO2 "SelY, TXDI2" ENSG00000211448 "Iodothyronine deiodinase 2" Q92813 14 80197526-80387757 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Thyroid hormones biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 163.9;thyroid gland: 355.8" "Cell type enhanced" "Detected in many" "Breast glandular cells: 150.7;Endometrial stromal cells: 158.3;Extravillous trophoblasts: 523.3;Muller glia cells: 246.4" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 34.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 80.8;fHDF/TERT166: 41.8;HeLa: 95.4;HHSteC: 44.2;SiHa: 168.1;SK-BR-3: 35.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048002 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA048002: AB_2680230" "unprognostic (1.22e-1)" "unprognostic (1.69e-1)" "prognostic favorable (1.67e-4)" "prognostic favorable (4.62e-6)" "unprognostic (2.76e-1)" "unprognostic (1.22e-1)" "unprognostic (2.22e-1)" "unprognostic (2.17e-1)" "unprognostic (2.07e-1)" "unprognostic (8.78e-2)" "unprognostic (3.68e-2)" "unprognostic (2.48e-1)" "unprognostic (1.00e-3)" "unprognostic (5.08e-2)" "unprognostic (3.43e-1)" "unprognostic (8.40e-2)" "unprognostic (7.15e-2)" 1.5 3.0 18.0 0.6 15.3 0.1 15.3 15.0 24.6 163.9 5.9 1.3 1.3 40.2 0.5 58.9 0.7 5.1 11.9 17.1 13.0 5.0 0.1 1.6 0.8 13.6 19.2 0.2 1.8 6.6 31.6 14.5 17.4 9.0 1.7 7.4 33.3 30.4 6.5 7.1 1.5 4.5 5.5 0.6 5.3 4.7 13.3 1.2 355.8 70.7 33.1 6.0 25.0 16.6 0.2 9.5 0.0 0.0 0.5 1.4 0.3 80.8 16.6 6.2 0.9 0.0 0.3 0.2 0.2 41.8 0.3 1.7 2.9 0.0 6.1 0.0 0.2 0.0 95.4 0.0 44.2 0.0 0.2 5.1 0.0 1.2 0.0 3.9 1.4 0.0 0.0 0.8 0.5 1.9 0.1 0.1 1.7 0.0 0.5 0.8 3.9 0.1 0.0 0.8 0.0 0.2 168.1 35.3 0.3 7.1 0.1 0.0 0.8 0.3 7.0 17.4 20.1 2.8 0.0 0.0 7.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 15.3 15.0 24.6 17.1 13.0 13.6 19.2 17.4 5.5 13.3 16.6 0.1 0.0 0.5 52.9 0.3 2.9 0.1 0.0 2.2 3.3 150.7 34.4 1.9 0.0 0.0 0.0 0.0 4.8 0.5 0.2 0.0 0.0 29.5 14.2 158.3 2.3 0.0 0.0 1.0 0.0 523.3 24.6 0.0 15.6 0.0 0.1 0.7 0.2 9.2 1.7 1.0 0.5 0.0 1.3 5.7 12.5 3.4 1.3 5.4 4.7 0.0 246.4 0.0 8.5 1.4 1.0 0.0 4.1 0.3 0.3 0.0 0.0 0.0 7.8 0.0 69.1 6.5 9.7 0.7 8.9 3.0 28.2 1.7 0.9 0.1 0.1 DIO3 TXDI3 ENSG00000197406 "Iodothyronine deiodinase 3" P55073 14 101561351-101563452 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Thyroid hormones biosynthesis" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 25.0;placenta: 17.8" "Cell type enhanced" "Detected in some" "Endothelial cells: 7.8;Fibroblasts: 27.9;Leydig cells: 10.8;Muller glia cells: 8.1;Peritubular cells: 7.5;Skeletal myocytes: 16.3;Syncytiotrophoblasts: 28.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "AF22: 54.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "amygdala: 4.4;hippocampal formation: 5.6" HPA073684 Supported Vesicles NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA073684: " "unprognostic (4.52e-3)" "unprognostic (1.80e-1)" "unprognostic (3.04e-3)" "unprognostic (3.48e-1)" "unprognostic (5.16e-2)" "unprognostic (1.50e-1)" "unprognostic (4.24e-2)" "unprognostic (8.11e-2)" "unprognostic (2.58e-1)" "unprognostic (6.24e-2)" "unprognostic (2.34e-1)" "unprognostic (2.52e-1)" "unprognostic (7.46e-5)" "unprognostic (4.82e-3)" "unprognostic (2.43e-1)" "unprognostic (1.11e-4)" "unprognostic (9.80e-3)" 5.0 0.4 0.5 1.8 1.2 0.0 3.2 0.2 1.2 25.0 0.2 1.7 0.0 6.5 0.6 1.8 6.7 3.0 0.6 0.6 0.2 0.3 3.9 2.6 1.3 1.3 0.3 13.6 1.5 0.0 0.7 17.8 0.3 3.2 0.4 0.7 1.7 2.2 1.6 3.5 1.7 0.9 0.4 0.6 1.6 1.3 3.3 0.2 4.1 3.0 0.1 5.2 15.4 0.4 0.0 0.2 54.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.1 0.0 0.0 1.0 1.3 0.8 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.2 0.2 1.2 0.6 0.2 1.3 0.3 0.3 0.4 3.3 0.4 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.6 0.4 0.0 0.0 0.0 0.0 1.9 0.0 5.9 0.0 0.6 0.3 0.4 4.9 7.8 0.0 0.0 0.1 0.0 2.5 27.9 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.5 0.0 0.0 0.7 0.6 10.8 0.1 0.0 0.0 0.6 8.1 0.0 0.0 0.0 0.9 1.1 7.5 0.0 0.8 0.0 0.0 0.0 0.2 0.0 16.3 0.7 0.1 0.2 0.2 0.1 28.3 0.2 0.1 0.3 0.4 DIP2C KIAA0934 ENSG00000151240 "Disco interacting protein 2 homolog C" Q9Y2E4 10 274190-689668 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Astrocytes: 125.4;Excitatory neurons: 219.3;Inhibitory neurons: 269.9;Oligodendrocyte precursor cells: 216.2;Oligodendrocytes: 421.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-2197: 33.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030264, HPA059325" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" Vesicles "HPA030264: AB_10600903, HPA059325: AB_2683979" "unprognostic (1.72e-2)" "unprognostic (3.39e-2)" "unprognostic (3.00e-2)" "prognostic unfavorable (8.92e-4)" "unprognostic (8.32e-2)" "unprognostic (1.50e-1)" "unprognostic (2.16e-2)" "unprognostic (1.58e-1)" "unprognostic (2.00e-1)" "unprognostic (6.28e-3)" "unprognostic (5.94e-2)" "unprognostic (3.65e-2)" "prognostic favorable (2.46e-6)" "unprognostic (8.52e-2)" "unprognostic (1.22e-1)" "unprognostic (1.09e-3)" "unprognostic (9.10e-3)" 12.7 7.7 13.8 3.7 18.3 0.2 8.3 18.8 19.9 11.0 0.0 22.1 4.5 12.1 5.4 9.1 8.8 8.6 14.1 13.6 10.7 14.7 8.9 4.9 2.4 16.8 14.6 13.3 8.0 8.1 6.2 4.6 17.4 8.4 4.4 9.4 4.2 9.1 34.5 4.8 7.0 12.4 7.2 3.3 7.3 7.2 18.1 2.1 5.3 20.8 1.5 10.5 7.5 32.6 0.7 6.3 11.5 6.1 19.0 20.5 9.5 13.9 8.6 10.5 8.5 1.8 1.9 0.5 3.6 22.5 2.7 0.1 7.1 1.2 6.4 0.3 6.4 0.1 4.5 2.0 9.2 0.0 8.6 16.9 5.5 6.6 0.0 16.4 2.3 0.1 0.0 1.2 8.0 17.4 0.7 0.0 3.0 5.4 2.6 9.9 4.8 2.0 7.5 7.2 5.8 8.2 2.4 5.0 20.1 6.0 6.6 0.0 0.1 11.1 2.9 33.3 4.6 0.8 14.3 7.2 13.9 0.3 6.4 0.0 0.1 0.0 0.1 0.0 0.1 0.7 0.2 0.2 0.0 1.0 0.3 0.3 0.0 0.1 0.0 0.1 0.1 0.1 13.8 18.3 18.8 19.9 13.6 10.7 16.8 14.6 17.4 7.2 18.1 32.6 12.6 9.6 5.8 125.4 4.0 7.9 5.4 2.2 7.4 18.6 11.8 10.0 30.3 17.2 4.7 3.7 22.9 5.2 0.6 2.2 0.0 8.5 19.0 7.9 18.5 7.8 10.8 0.0 219.3 4.0 5.8 15.4 10.2 8.8 20.3 16.3 10.4 24.2 6.2 1.7 269.9 6.2 2.0 3.5 5.2 6.1 11.5 3.6 23.2 44.0 0.6 19.4 1.0 216.2 421.7 7.7 1.3 19.5 0.9 7.7 10.2 17.0 5.3 20.5 6.6 22.7 17.6 21.7 22.5 4.3 3.8 3.8 2.0 5.6 5.7 8.9 DIPK1B "C9orf136, FAM69B, MGC20262" ENSG00000165716 "Divergent protein kinase domain 1B" Q5VUD6 9 136712572-136724742 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 15 "Adipocytes: 23.1;Cardiomyocytes: 7.3;Endothelial cells: 6.9;Extravillous trophoblasts: 6.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.8" "Group enriched" "Detected in many" 9 "B-cells: 2.8;dendritic cells: 1.0" "Cell line enhanced" "Detected in many" "EFO-21: 56.4;HEK 293: 58.2;HUVEC TERT2: 65.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054443 Approved "Nucleoplasm,Nuclear bodies,Vesicles" No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear bodies" "Nucleoplasm, Vesicles" "HPA054443: AB_2682489" "unprognostic (2.78e-2)" "unprognostic (8.07e-2)" "prognostic unfavorable (1.77e-5)" "unprognostic (3.82e-1)" "unprognostic (1.37e-1)" "unprognostic (5.59e-2)" "unprognostic (1.71e-1)" "unprognostic (6.74e-2)" "unprognostic (6.80e-2)" "unprognostic (2.10e-2)" "prognostic favorable (9.48e-5)" "unprognostic (2.77e-1)" "unprognostic (6.67e-3)" "unprognostic (4.14e-2)" "unprognostic (1.21e-2)" "unprognostic (1.84e-1)" "unprognostic (2.78e-1)" 17.4 4.8 21.7 3.7 20.3 9.1 14.0 25.7 26.8 14.9 18.7 12.3 5.4 16.8 2.1 4.9 16.7 5.5 35.9 20.1 20.0 17.8 11.4 16.4 5.8 23.5 21.1 11.5 14.3 12.8 25.1 18.7 24.2 13.6 0.8 5.9 9.8 3.1 8.9 11.5 7.7 3.0 17.3 8.6 6.8 15.0 24.2 1.7 16.8 3.8 1.3 8.0 7.7 19.4 3.2 11.3 25.3 21.0 0.0 0.0 19.5 2.9 0.0 0.8 0.9 27.7 6.6 9.2 56.4 0.0 7.9 13.5 11.7 0.3 0.2 8.1 58.2 13.5 4.7 5.9 0.2 7.0 9.0 0.2 0.0 0.3 0.1 10.1 65.2 19.7 14.8 4.2 0.0 14.8 10.8 28.3 36.9 12.6 9.7 49.9 1.9 26.2 1.4 3.7 38.5 38.3 1.8 8.2 27.4 8.7 18.3 21.9 33.3 5.6 18.7 5.3 6.8 12.9 3.3 8.9 3.2 6.7 10.1 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.1 0.0 0.0 2.8 0.2 0.1 0.0 0.0 0.0 1.0 0.1 0.3 21.7 20.3 25.7 26.8 20.1 20.0 23.5 21.1 24.2 17.3 24.2 19.4 23.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 6.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 DIRAS1 "Di-Ras1, GBTS1, RIG" ENSG00000176490 "DIRAS family GTPase 1" O95057 19 2714567-2721372 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.8;heart muscle: 105.0;tongue: 51.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 18.0;Distal tubular cells: 31.3;Excitatory neurons: 20.4;Horizontal cells: 89.2;Inhibitory neurons: 25.9" "Cancer enhanced" "Detected in many" "glioma: 17.4;melanoma: 13.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 43.4;REH: 49.2;SH-SY5Y: 27.8;THP-1: 34.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050164 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 62: Horizontal cells - Visual perception" "Vesicles, Plasma membrane" Nucleoplasm "HPA050164: " "unprognostic (7.43e-2)" "unprognostic (1.13e-1)" "unprognostic (2.33e-2)" "unprognostic (1.66e-1)" "unprognostic (1.49e-1)" "unprognostic (4.19e-3)" "unprognostic (8.01e-3)" "unprognostic (2.68e-1)" "unprognostic (5.62e-2)" "unprognostic (3.60e-2)" "prognostic favorable (4.78e-4)" "unprognostic (3.00e-1)" "unprognostic (1.79e-3)" "unprognostic (5.47e-3)" "unprognostic (1.51e-1)" "unprognostic (1.03e-1)" "unprognostic (6.91e-4)" 1.8 2.5 10.5 1.2 20.7 0.7 1.9 16.1 84.8 7.0 0.0 1.4 1.2 12.7 2.5 5.4 6.6 0.7 105.0 19.8 16.9 4.8 0.1 0.6 0.6 17.1 17.4 2.7 6.7 17.0 22.4 0.3 14.5 3.3 1.1 11.5 6.7 1.8 2.7 1.9 2.2 7.4 0.0 4.2 3.5 6.0 45.2 0.1 0.5 51.8 0.7 4.0 2.4 34.8 0.1 2.2 7.0 24.1 0.9 3.1 0.1 8.2 2.8 0.4 0.1 1.4 0.4 0.0 1.0 21.9 12.2 0.1 10.1 0.0 0.0 0.0 15.6 0.5 0.8 0.9 1.0 0.0 43.4 1.4 5.1 0.1 0.1 4.6 0.0 0.2 15.0 7.2 2.8 3.6 0.2 0.4 15.2 0.0 3.3 49.2 0.0 11.7 0.0 0.0 3.1 27.8 0.3 1.1 15.6 1.2 1.1 34.2 0.0 5.3 6.6 0.2 2.6 16.4 12.4 8.9 11.8 0.5 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 20.7 16.1 84.8 19.8 16.9 17.1 17.4 14.5 0.0 45.2 34.8 0.0 0.0 0.0 1.6 6.9 1.1 0.8 0.2 2.2 7.9 2.6 2.8 18.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 31.3 1.4 0.4 0.1 2.2 0.3 0.0 1.3 20.4 2.0 0.5 0.9 0.0 0.3 0.0 2.3 0.0 0.0 5.7 89.2 25.9 0.0 0.0 0.0 3.6 1.1 1.2 0.5 3.6 4.7 0.1 4.6 0.0 2.0 3.4 1.5 0.0 0.0 0.6 0.9 0.0 0.1 0.0 6.1 0.0 0.7 2.1 0.7 0.4 0.3 0.4 0.3 0.1 0.0 0.0 0.2 DISP2 "C15orf36, DISPB, HsT16908, KIAA1742, LINC00594" ENSG00000140323 "Dispatched RND transporter family member 2" A7MBM2 15 40358219-40378621 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "brain: 17.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 19.0;Distal enterocytes: 16.8;Horizontal cells: 18.5;Intestinal goblet cells: 18.2;Proximal enterocytes: 12.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 4.2;HaCaT: 6.6;SCLC-21H: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059903 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Vesicles" "HPA059903: AB_2684156" "unprognostic (3.43e-4)" "unprognostic (7.65e-3)" "unprognostic (4.14e-2)" "unprognostic (2.30e-3)" "unprognostic (1.90e-1)" "unprognostic (1.25e-1)" "unprognostic (4.02e-2)" "unprognostic (3.08e-2)" "unprognostic (1.98e-1)" "unprognostic (2.13e-2)" "unprognostic (1.45e-1)" "unprognostic (6.75e-2)" "unprognostic (4.47e-8)" "unprognostic (1.96e-1)" "unprognostic (3.02e-1)" "unprognostic (2.08e-1)" "unprognostic (1.71e-1)" 0.2 0.7 5.1 0.4 4.7 0.3 0.1 17.6 5.7 0.3 0.0 1.5 1.1 0.2 0.1 0.1 0.2 0.2 0.1 3.6 3.9 0.0 0.1 0.1 0.4 5.5 1.6 0.3 0.3 0.1 1.3 0.2 5.8 0.1 1.2 1.6 0.3 0.4 0.1 0.3 1.2 0.3 0.4 0.2 1.2 0.7 4.5 0.2 1.4 0.0 0.0 0.1 0.1 1.9 1.3 0.5 0.3 2.0 0.1 0.0 0.7 0.2 0.1 0.8 1.2 1.9 0.6 0.2 1.3 0.8 4.2 6.6 0.2 1.1 0.5 0.1 0.4 0.3 0.4 0.1 0.0 0.4 1.1 1.4 0.0 0.2 0.1 0.2 0.4 0.7 0.5 0.8 1.1 0.3 0.2 0.3 0.3 1.7 0.9 0.2 0.3 0.4 0.2 1.7 13.4 1.9 0.2 0.1 0.2 0.3 0.3 0.2 0.4 0.9 0.7 0.2 0.2 0.2 0.1 0.2 0.3 0.5 1.8 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.2 0.0 0.2 0.0 0.0 5.1 4.7 17.6 5.7 3.6 3.9 5.5 1.6 5.8 0.4 4.5 1.9 0.9 3.2 3.6 1.0 0.5 0.0 1.9 0.0 0.0 19.0 0.8 1.3 1.7 1.5 4.4 3.7 10.4 0.2 0.2 16.8 0.0 0.4 1.3 0.3 0.6 1.4 9.6 2.7 5.1 0.4 0.3 1.6 5.1 0.5 8.8 0.4 0.4 0.4 1.0 18.5 7.0 18.2 0.0 0.6 0.0 1.8 1.2 1.1 0.0 1.0 0.3 2.3 4.1 4.0 0.3 0.3 3.2 0.0 0.3 1.2 12.1 0.2 2.2 7.6 0.0 3.1 0.8 4.1 6.1 0.0 0.0 0.3 1.1 0.8 8.6 1.1 DKK3 "REIC, RIG" ENSG00000050165 "Dickkopf WNT signaling pathway inhibitor 3" Q9UBP4 11 11956207-12009769 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 1224.0" "Group enriched" "Detected in many" 7 "Cardiomyocytes: 884.3;Muller glia cells: 1960.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 6.2;memory CD8 T-cell: 3.8" "Lineage enriched" "Detected in single" 62 "T-cells: 6.2" "Cell line enhanced" "Detected in many" "BJ: 418.9;BJ hTERT+: 643.0;fHDF/TERT166: 614.4;hTERT-RPE1: 370.2;TIME: 349.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011868, CAB024949" Approved Supported "Nuclear bodies,Vesicles,Cytosol" "Secreted in other tissues" No No 18000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Nuclear bodies, Cytosol" "CAB024949: , HPA011868: AB_1847716" "unprognostic (4.24e-2)" "unprognostic (6.40e-2)" "unprognostic (1.96e-1)" "unprognostic (7.84e-2)" "unprognostic (3.06e-3)" "unprognostic (6.58e-3)" "unprognostic (1.14e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-3)" "unprognostic (5.28e-2)" "unprognostic (4.51e-2)" "unprognostic (3.87e-2)" "prognostic unfavorable (6.31e-5)" "unprognostic (7.41e-3)" "unprognostic (1.09e-1)" "unprognostic (2.97e-2)" "unprognostic (1.02e-3)" 31.2 79.1 110.7 10.0 183.6 0.2 26.0 12.6 135.2 89.7 104.8 53.2 14.6 47.0 16.7 29.7 23.0 67.0 1224.0 147.7 80.2 17.0 5.6 123.7 8.5 95.1 54.3 38.1 18.2 34.2 38.2 25.0 46.8 59.4 13.0 204.1 30.9 78.1 7.8 29.7 24.6 43.1 83.9 33.2 31.7 30.9 99.9 4.7 16.4 18.8 5.4 40.9 48.3 121.6 1.5 13.1 18.1 0.1 15.3 29.7 0.6 418.9 643.0 182.4 205.5 9.6 3.2 0.0 44.8 614.4 96.8 64.4 1.5 181.9 69.5 0.1 0.5 0.0 1.7 0.0 113.6 0.0 0.3 45.3 60.0 61.9 151.3 370.2 195.3 0.0 0.2 0.4 256.4 0.0 0.1 0.4 8.6 0.0 0.5 0.1 1.2 0.1 62.5 0.6 0.5 53.2 2.0 0.0 0.2 47.9 0.2 0.5 349.7 107.5 82.8 11.2 110.3 0.1 0.0 0.3 18.1 0.0 103.5 0.0 0.0 0.0 0.5 0.0 6.2 0.0 0.6 3.8 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 110.7 183.6 12.6 135.2 147.7 80.2 95.1 54.3 46.8 83.9 99.9 121.6 5.8 3.2 3.0 94.3 0.1 45.6 59.5 70.3 93.4 31.6 3.2 103.2 884.3 0.0 12.8 0.0 12.5 0.5 0.4 0.0 0.0 0.8 104.3 0.7 8.4 32.9 1.8 0.0 90.4 0.2 0.8 106.1 7.1 0.6 1.3 17.0 66.8 0.4 20.4 13.5 83.7 0.1 0.0 1.3 12.5 88.5 20.5 1.4 64.0 38.4 0.0 1960.4 0.0 27.6 14.7 1.1 0.1 57.6 1.7 32.8 0.0 0.2 2.9 67.5 190.7 12.7 83.4 1.2 3.2 5.8 14.8 0.8 4.1 0.5 0.3 3.0 DKKL1 "CT34, SGY-1" ENSG00000104901 "Dickkopf like acrosomal protein 1" Q9UK85 19 49361783-49375116 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 277 "testis: 344.8" "Group enriched" "Detected in some" 4 "Early spermatids: 2188.8;Late spermatids: 2340.4" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "memory B-cell: 1.7" "Lineage enriched" "Detected in single" 17 "B-cells: 1.7" "Cell line enhanced" "Detected in some" "AF22: 5.1;AN3-CA: 9.8;HeLa: 2.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB025410, HPA047194" Enhanced Approved Vesicles "Secreted in male reproductive system" NA NA "Cluster 37: B-cells - Transcription" "Cluster 36: Testis - Spermatogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "CAB025410: , HPA047194: AB_2679979" "unprognostic (1.64e-1)" "unprognostic (5.30e-1)" "unprognostic (5.39e-4)" "unprognostic (1.85e-4)" "unprognostic (3.79e-2)" "unprognostic (4.30e-2)" "unprognostic (5.52e-4)" "unprognostic (1.00e-1)" "unprognostic (6.76e-2)" "unprognostic (4.08e-1)" "unprognostic (1.90e-1)" "unprognostic (5.65e-2)" "unprognostic (2.56e-3)" "unprognostic (1.36e-1)" "unprognostic (1.13e-1)" "unprognostic (1.18e-1)" "unprognostic (5.57e-2)" 0.7 0.5 0.3 0.5 0.3 0.0 0.5 0.2 0.5 0.7 0.4 0.5 0.3 1.1 0.3 0.2 1.2 0.7 0.4 0.2 0.1 0.6 0.3 0.3 0.5 0.4 0.3 0.8 1.0 0.1 0.1 0.3 0.2 0.6 0.1 0.3 0.9 0.6 0.2 0.2 0.3 0.4 0.3 0.4 0.3 344.8 0.2 0.0 0.2 0.4 0.2 0.4 0.4 0.3 0.0 1.2 5.1 9.8 0.0 0.3 0.4 0.9 0.0 0.1 0.3 0.0 0.5 0.0 0.7 0.1 0.4 0.0 0.1 0.0 0.0 0.0 1.7 0.0 2.9 0.2 0.0 0.0 0.9 0.7 0.3 0.2 0.3 0.9 0.8 0.0 1.2 0.3 0.1 0.4 0.0 0.0 2.0 0.5 1.1 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.9 0.0 0.5 1.0 1.0 2.0 1.2 1.0 0.6 0.6 0.0 0.4 0.6 0.2 0.0 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.5 0.2 0.1 0.4 0.3 0.2 0.3 0.2 0.3 1.3 0.0 0.0 0.0 0.4 0.1 0.1 0.1 0.6 0.6 1.2 2.2 0.4 0.0 0.1 0.0 2.1 0.0 0.0 0.1 0.0 0.4 2188.8 0.5 1.0 1.9 0.0 0.0 0.2 0.5 0.2 0.7 0.0 0.2 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 2340.4 16.8 1.4 1.8 0.0 0.0 2.1 0.0 0.0 0.0 0.3 0.0 12.0 0.0 0.2 0.0 0.0 0.0 0.4 6.6 0.7 0.9 491.0 15.2 0.2 0.0 0.0 0.1 0.5 0.2 0.2 DLC1 "ARHGAP7, DLC-1, HP, p122-RhoGAP, STARD12" ENSG00000164741 "DLC1 Rho GTPase activating protein" Q96QB1 8 13083361-13604610 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 250.0;Alveolar cells type 2: 225.9;Excitatory neurons: 208.8;Microglial cells: 317.6;Oligodendrocyte precursor cells: 244.3;Oligodendrocytes: 707.2;Sertoli cells: 223.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "basophil: 4.3;non-classical monocyte: 1.1" "Group enriched" "Detected in many" 19 "granulocytes: 4.3;monocytes: 1.1" "Cell line enhanced" "Detected in many" "HBF TERT88: 83.2;U-2197: 98.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017753 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" Nucleoplasm "HPA017753: AB_10600805" "unprognostic (1.83e-1)" "unprognostic (1.67e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.11e-4)" "unprognostic (7.47e-2)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (1.12e-1)" "unprognostic (8.46e-3)" "unprognostic (6.49e-2)" "unprognostic (2.02e-2)" "unprognostic (3.56e-3)" "unprognostic (2.79e-2)" "unprognostic (7.33e-2)" "unprognostic (1.67e-1)" 52.5 10.6 17.8 8.8 28.7 2.6 29.6 21.8 18.2 13.5 4.8 19.6 5.6 16.1 5.3 6.3 14.7 19.1 21.5 22.9 21.3 13.7 20.4 42.9 3.8 27.8 23.5 9.5 9.0 6.1 5.3 24.2 29.0 6.7 6.2 1.5 5.6 4.2 7.2 7.1 11.5 19.1 18.8 16.4 13.6 4.0 22.5 2.1 15.7 10.3 1.8 15.4 11.1 38.0 0.1 0.7 6.6 0.0 69.4 35.5 20.3 39.3 33.7 40.7 48.6 11.5 6.6 0.0 9.7 51.4 39.4 6.6 4.3 7.4 83.2 0.0 7.2 39.5 0.1 21.7 31.8 0.0 13.7 36.6 0.6 62.6 46.7 43.3 46.7 0.1 2.7 0.0 33.6 0.8 0.0 0.0 0.7 1.4 4.7 0.0 0.0 0.0 19.7 24.4 0.0 2.9 0.0 1.1 31.8 27.4 0.0 0.0 61.7 45.5 18.8 98.7 15.3 0.1 0.0 0.0 31.6 0.3 63.4 4.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 17.8 28.7 21.8 18.2 22.9 21.3 27.8 23.5 29.0 18.8 22.5 38.0 171.7 250.0 225.9 177.3 2.3 14.8 2.5 4.8 5.2 0.9 9.3 8.3 37.8 24.3 19.7 3.7 0.0 7.8 0.6 0.4 1.9 3.1 8.4 15.3 36.1 138.4 1.2 25.2 208.8 4.4 2.3 74.2 4.6 27.3 68.2 0.1 193.1 25.7 3.6 13.5 151.8 1.2 0.0 18.6 17.0 4.3 72.4 6.2 24.9 317.6 0.2 1.0 0.0 244.3 707.2 3.0 1.3 36.1 1.9 1.4 6.1 1.9 3.0 1.9 223.5 50.0 138.0 6.2 11.4 1.8 9.2 2.7 3.6 31.1 2.9 1.7 DLG1 "dJ1061C18.1.1, DLGH1, hdlg, SAP-97, SAP97" ENSG00000075711 "Discs large MAGUK scaffold protein 1" Q12959 3 197042560-197299330 "Predicted intracellular proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 422.9;Oligodendrocytes: 1542.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016307, HPA069593" Supported Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "Plasma membrane" "CAB016307: AB_2092015, HPA069593: " "unprognostic (2.04e-2)" "unprognostic (1.37e-1)" "unprognostic (7.79e-2)" "unprognostic (4.56e-3)" "unprognostic (3.54e-2)" "unprognostic (8.56e-2)" "unprognostic (8.90e-3)" "unprognostic (2.97e-1)" "unprognostic (5.98e-2)" "unprognostic (2.33e-1)" "unprognostic (2.41e-2)" "unprognostic (3.40e-2)" "unprognostic (1.70e-3)" "unprognostic (3.56e-1)" "unprognostic (2.46e-1)" "unprognostic (1.33e-1)" "unprognostic (3.07e-1)" 20.7 14.5 26.4 14.7 57.0 16.2 18.4 33.2 36.4 23.8 15.4 24.2 24.0 19.7 11.6 37.6 16.1 17.1 19.4 25.4 29.3 27.6 25.9 18.0 14.7 36.9 43.3 23.3 17.2 31.7 14.4 21.3 34.8 15.9 26.3 38.8 20.2 18.6 25.2 18.8 25.4 21.2 19.9 13.0 22.9 15.5 50.3 27.1 43.3 28.2 20.6 20.3 20.5 73.5 128.0 20.0 40.3 75.7 34.2 36.2 40.7 52.2 46.2 49.2 59.0 60.4 59.8 41.5 127.1 47.7 95.7 86.4 39.3 76.4 97.7 10.9 22.5 35.2 31.1 40.5 35.2 35.0 33.3 27.8 43.3 49.1 101.3 163.1 64.8 32.2 26.7 51.4 125.6 41.5 51.3 12.9 35.3 71.1 35.4 26.7 51.6 26.8 51.9 55.3 19.7 32.3 72.9 49.5 49.4 46.7 108.8 26.0 62.5 127.5 33.5 36.1 79.9 76.0 50.6 50.6 50.3 51.8 40.0 2.5 0.7 1.2 0.8 0.7 1.3 1.6 1.3 0.9 0.8 1.2 1.3 1.3 2.4 1.1 0.4 1.1 1.0 0.8 26.4 57.0 33.2 36.4 25.4 29.3 36.9 43.3 34.8 19.9 50.3 73.5 24.0 25.6 25.7 113.3 28.5 53.3 52.3 45.5 40.5 42.0 29.6 23.0 25.6 35.8 44.6 49.7 95.9 48.9 25.2 72.4 5.9 22.8 12.9 51.8 37.4 28.1 28.9 17.5 422.9 20.2 19.5 27.7 51.5 68.5 12.0 29.9 27.8 54.6 14.9 37.0 117.8 34.4 28.5 26.4 26.0 19.2 28.6 19.2 37.4 165.8 18.3 71.9 43.3 257.3 1542.2 30.3 48.0 25.6 34.1 52.3 50.6 20.8 66.3 101.7 13.1 40.5 25.5 31.2 37.9 66.7 70.8 25.0 30.6 29.3 38.8 106.8 DLG2 "chapsyn-110, PPP1R58, PSD-93, PSD93" ENSG00000150672 "Discs large MAGUK scaffold protein 2" Q15700 11 83455012-85627922 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 88.4" "Group enriched" "Detected in many" 4 "Excitatory neurons: 3292.3;Inhibitory neurons: 2602.7;Oligodendrocyte precursor cells: 2331.8;Oligodendrocytes: 4213.8" "Cancer enhanced" "Detected in some" "glioma: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 8.2;SH-SY5Y: 8.1;T-47d: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021307, HPA023896, CAB072341" Enhanced Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 6: T47d - Mammary gland" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Vesicles "CAB072341: , HPA021307: AB_1846625, HPA023896: AB_2671353" "unprognostic (2.61e-3)" "unprognostic (2.81e-2)" "unprognostic (4.05e-2)" "unprognostic (9.03e-2)" "unprognostic (3.25e-1)" "unprognostic (1.09e-1)" "unprognostic (9.44e-3)" "unprognostic (7.78e-2)" "unprognostic (4.32e-1)" "unprognostic (4.61e-2)" "unprognostic (9.28e-3)" "unprognostic (4.84e-1)" "unprognostic (7.66e-6)" "unprognostic (2.92e-2)" "unprognostic (2.41e-1)" "unprognostic (6.52e-2)" "unprognostic (8.89e-2)" 1.6 11.0 29.5 1.1 48.7 0.3 2.1 3.6 55.8 1.8 0.0 2.3 1.2 2.9 4.1 7.5 5.7 2.1 3.0 64.4 18.1 3.6 2.8 1.7 1.1 13.5 8.2 5.7 3.3 7.3 10.0 2.4 10.3 4.0 1.4 25.4 3.1 4.6 0.8 20.2 1.2 2.2 11.9 2.5 1.5 8.1 10.5 7.3 15.5 0.7 2.9 1.7 2.6 88.4 0.6 0.3 0.9 0.5 0.6 0.7 8.2 0.2 0.5 0.4 0.3 7.4 1.1 1.3 1.3 0.4 0.5 0.8 2.3 0.7 0.4 0.8 0.9 1.3 5.0 0.2 0.1 0.4 1.1 0.5 0.5 1.0 1.0 0.4 0.5 1.9 1.2 3.5 0.7 0.9 0.6 1.3 6.0 0.8 1.3 1.4 2.0 0.9 0.4 0.3 5.9 8.1 0.8 5.1 0.4 7.2 21.2 0.0 0.3 2.2 1.8 2.1 0.3 0.8 2.9 5.6 0.8 0.7 0.2 0.0 0.0 0.2 0.1 0.0 0.5 0.1 0.1 0.2 0.0 0.6 0.6 0.2 0.0 0.0 0.1 0.5 0.0 0.0 29.5 48.7 3.6 55.8 64.4 18.1 13.5 8.2 10.3 11.9 10.5 88.4 7.0 3.2 10.4 742.8 1.3 3.3 3.6 0.3 9.1 298.1 4.4 5.2 8.3 2.8 1.8 7.3 275.2 7.9 1.8 1.5 9.8 0.7 21.5 1.3 2.7 3.6 4.2 0.0 3292.3 0.4 0.5 7.4 1.1 2.4 0.0 1.6 2.2 4.6 4.0 23.5 2602.7 1.1 0.0 0.3 0.0 16.4 7.8 0.8 1.8 487.2 0.6 11.0 0.0 2331.8 4213.8 0.4 0.1 6.4 0.1 2.0 0.6 2.7 0.9 48.2 6.6 7.1 4.1 11.3 3.2 6.2 8.5 2.1 1.7 12.1 0.9 0.8 DLGAP1 "DAP-1, GKAP, SAPAP1" ENSG00000170579 "DLG associated protein 1" O14490 18 3496032-4455307 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.4" "Group enriched" "Detected in many" 7 "Excitatory neurons: 2145.5;Inhibitory neurons: 3599.2;Oligodendrocyte precursor cells: 1264.6" "Cancer enhanced" "Detected in many" "glioma: 2.4" "Region enhanced" "Detected in many" "cerebral cortex: 39.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 10.7;HAP1: 3.7;U-2197: 3.3;U-87 MG: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078234 Approved Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Cytosol" "HPA078234: " "unprognostic (2.50e-3)" "unprognostic (7.82e-2)" "unprognostic (2.40e-1)" "unprognostic (1.98e-1)" "unprognostic (1.07e-2)" "unprognostic (3.63e-3)" "unprognostic (2.73e-2)" "unprognostic (1.97e-2)" "unprognostic (2.93e-3)" "unprognostic (5.49e-3)" "unprognostic (5.87e-4)" "unprognostic (2.18e-1)" "unprognostic (2.78e-3)" "unprognostic (3.10e-2)" "unprognostic (4.93e-3)" "unprognostic (8.93e-2)" "unprognostic (9.68e-2)" 0.4 4.3 8.3 0.2 18.3 0.0 1.5 4.4 39.4 0.6 0.0 0.3 0.1 0.7 8.2 0.2 6.5 4.1 0.4 24.0 0.0 1.2 0.1 0.7 0.2 0.0 0.0 1.9 0.2 0.0 2.4 0.6 0.0 2.9 0.2 3.2 1.9 10.1 0.1 0.2 0.2 0.3 0.0 0.5 0.1 3.7 0.0 0.1 0.5 0.4 0.1 0.5 0.6 7.4 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 10.7 0.0 0.2 1.1 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.5 0.2 0.0 0.9 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.0 1.4 0.8 1.2 0.0 0.1 0.0 0.8 0.2 0.0 0.0 0.0 0.0 1.0 3.3 0.0 0.2 0.0 0.1 2.3 0.0 0.9 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 18.3 4.4 39.4 24.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 1.5 0.0 4.6 309.8 0.3 0.8 0.3 0.3 5.7 23.6 6.6 2.8 3.1 7.2 0.1 1.8 0.0 0.1 0.1 0.4 0.0 0.2 11.4 31.7 8.3 1.9 3.0 0.0 2145.5 0.2 0.1 1.8 0.5 94.6 0.0 0.0 2.2 0.0 0.2 0.0 3599.2 1.7 0.0 0.0 0.7 13.8 0.6 0.6 12.4 72.1 0.1 0.2 0.0 1264.6 31.0 0.2 0.1 0.4 0.0 3.5 0.0 5.4 4.4 1.4 0.0 0.7 2.2 12.9 4.8 1.6 0.1 0.3 0.8 0.1 0.1 0.1 DLK2 "EGFL9, MGC2487" ENSG00000171462 "Delta like non-canonical Notch ligand 2" Q6UY11 6 43450352-43456632 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 12.3;prostate: 12.9;skin 1: 12.7" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 96.9;Basal respiratory cells: 56.8;Basal squamous epithelial cells: 64.3;Breast myoepithelial cells: 26.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 24.1;HBEC3-KT: 13.1;hTCEpi: 38.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA061223, HPA068672, HPA070955" Uncertain Approved Nucleoplasm,Nucleoli,Vesicles No No "Cluster 40: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Nucleoli, Vesicles" "HPA061223: AB_2684454, HPA068672: AB_2686017, HPA070955: " "unprognostic (4.65e-5)" "unprognostic (1.27e-1)" "unprognostic (1.69e-1)" "unprognostic (9.68e-4)" "unprognostic (2.87e-1)" "unprognostic (3.80e-1)" "unprognostic (4.19e-3)" "unprognostic (1.65e-1)" "unprognostic (2.65e-3)" "unprognostic (4.04e-1)" "unprognostic (1.88e-2)" "unprognostic (1.88e-1)" "unprognostic (9.27e-12)" "unprognostic (7.71e-4)" "unprognostic (8.92e-2)" "unprognostic (1.55e-1)" "unprognostic (6.43e-2)" 0.8 0.5 3.8 0.7 4.5 0.9 2.9 6.9 7.0 2.9 1.8 0.4 0.4 0.6 2.0 12.3 0.6 0.3 1.7 4.4 4.2 0.5 0.7 0.5 0.9 2.7 2.6 1.1 0.8 0.1 0.8 0.6 2.7 12.9 0.0 0.6 8.1 5.2 0.2 12.7 0.6 0.1 2.6 0.7 0.4 1.0 3.5 2.3 0.7 0.0 0.9 0.8 6.7 3.2 7.9 2.8 0.8 11.3 0.0 0.6 2.5 2.8 3.0 3.1 1.4 2.7 0.4 1.5 1.7 0.5 3.8 24.1 8.0 13.1 0.7 1.5 3.0 0.6 1.5 4.2 0.8 0.5 1.6 1.3 38.5 0.9 7.1 1.0 0.0 4.5 0.7 1.1 1.2 3.0 0.6 0.6 1.0 3.0 2.9 1.6 1.4 0.7 0.4 2.6 8.3 0.8 0.9 0.3 0.4 0.6 0.7 2.4 0.8 1.1 3.6 0.8 5.6 1.8 0.4 2.5 0.1 1.1 0.8 0.3 0.1 0.1 0.1 0.0 0.8 0.1 0.5 0.5 0.0 0.2 0.2 0.1 0.2 0.8 0.1 0.5 0.0 0.1 3.8 4.5 6.9 7.0 4.4 4.2 2.7 2.6 2.7 2.6 3.5 3.2 0.3 0.0 0.5 0.3 0.4 10.1 96.9 56.8 64.3 1.3 0.6 26.7 0.6 0.0 6.0 0.0 0.0 1.3 0.5 0.0 0.0 0.1 0.3 0.1 3.0 0.7 1.2 0.0 6.1 0.0 2.7 0.4 0.0 0.2 0.0 4.7 0.0 0.0 0.1 11.8 2.8 0.0 2.0 0.0 0.4 0.5 0.3 0.6 1.8 2.8 0.0 0.6 0.0 3.0 0.9 0.1 0.0 0.0 0.1 12.9 0.0 0.0 1.1 1.2 0.0 0.5 1.1 1.7 7.0 6.7 2.6 0.3 1.3 0.4 0.0 8.3 DLX1 ENSG00000144355 "Distal-less homeobox 1" P56177 2 172084740-172089677 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 18.8" "Cell type enriched" "Detected in some" 23 "Inhibitory neurons: 30.4" "Cancer enhanced" "Detected in many" "prostate cancer: 11.1" "Region enhanced" "Detected in many" "hypothalamus: 18.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 134.5;U-138 MG: 36.9;WM-115: 42.1" "Group enriched" "Detected in many" 5 "basal ganglia: 28.6;olfactory bulb: 82.6" "Region enriched" "Detected in many" 4 "olfactory bulb: 48.8" "HPA007175, HPA045884" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 65: Brain - Ion transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Vesicles, Cytosol" "HPA007175: , HPA045884: AB_10960361" "unprognostic (2.14e-2)" "unprognostic (5.09e-2)" "unprognostic (3.92e-2)" "unprognostic (1.89e-3)" "unprognostic (1.18e-1)" "unprognostic (1.18e-1)" "unprognostic (7.92e-3)" "unprognostic (8.86e-2)" "unprognostic (2.80e-2)" "unprognostic (2.03e-1)" "unprognostic (5.74e-2)" "unprognostic (2.04e-1)" "unprognostic (7.40e-9)" "unprognostic (2.22e-1)" "unprognostic (9.19e-2)" "unprognostic (1.25e-1)" "unprognostic (5.91e-3)" 0.1 1.3 5.9 0.2 4.8 0.0 0.1 0.0 4.4 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.2 3.5 18.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.2 0.0 0.1 0.0 0.1 0.5 0.2 0.1 0.0 0.0 0.1 0.0 3.5 0.0 1.0 0.1 0.3 0.1 0.2 2.7 2.4 0.6 0.6 134.5 2.0 4.5 0.3 3.2 6.5 7.7 4.1 1.0 0.2 0.0 7.8 7.2 7.5 9.4 7.4 1.2 5.2 0.3 33.3 21.1 14.4 5.7 0.1 7.9 15.9 0.0 2.2 1.9 3.2 5.4 0.0 6.7 12.4 0.0 6.3 8.1 0.1 1.9 0.1 0.0 22.9 0.4 15.8 0.0 0.9 4.5 11.3 0.0 6.1 0.8 17.5 0.4 5.2 9.5 7.1 36.9 0.2 16.4 16.4 0.2 0.0 0.1 15.2 21.4 42.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.9 4.8 0.0 4.4 3.5 18.8 0.0 0.2 0.0 0.0 3.5 2.7 0.1 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 30.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DMPK "DM, DM1, DM1PK, DMK, MDPK, MT-PK" ENSG00000104936 "DM1 protein kinase" Q09013 19 45769709-45782552 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 44.1;Sertoli cells: 59.2;Smooth muscle cells: 34.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 85.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 8.7" "HPA007164, HPA008905" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol Vesicles "HPA007164: AB_1078687, HPA008905: AB_1078685" "unprognostic (7.44e-2)" "unprognostic (2.66e-1)" "unprognostic (1.76e-3)" "unprognostic (2.61e-3)" "unprognostic (1.29e-1)" "unprognostic (5.46e-2)" "unprognostic (8.67e-2)" "unprognostic (1.50e-1)" "unprognostic (1.31e-1)" "unprognostic (1.67e-1)" "prognostic favorable (9.39e-5)" "unprognostic (1.93e-1)" "unprognostic (1.60e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-1)" "unprognostic (3.03e-2)" "unprognostic (4.24e-3)" 24.2 68.3 22.1 17.5 24.0 3.0 19.1 22.2 33.1 42.8 25.6 121.5 15.8 92.7 5.3 33.4 61.2 13.9 171.3 21.8 21.6 20.3 8.8 29.8 5.2 24.0 23.8 31.1 34.3 2.9 37.9 8.8 22.3 56.4 4.8 4.1 18.6 37.6 173.6 12.3 34.6 59.9 21.9 17.8 51.7 13.2 23.8 4.2 21.7 143.2 1.3 69.1 34.3 21.3 11.7 16.7 13.5 10.7 13.4 12.9 10.5 26.1 22.2 10.5 8.8 2.2 6.6 2.9 2.8 32.9 9.2 15.1 3.0 1.5 2.2 12.4 16.6 0.8 22.6 1.4 12.6 0.1 5.4 22.8 8.0 6.4 1.7 24.2 3.6 2.1 8.6 8.0 15.4 13.7 1.6 3.8 8.8 4.8 3.3 5.0 85.1 6.4 4.7 11.5 10.2 13.5 13.6 27.6 9.3 4.8 28.6 5.5 8.4 9.2 10.4 8.3 15.0 16.8 11.5 2.9 9.5 1.3 13.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.1 24.0 22.2 33.1 21.8 21.6 24.0 23.8 22.3 21.9 23.8 21.3 10.5 0.0 2.2 44.1 3.7 8.0 8.1 3.8 5.7 5.7 9.6 9.9 3.7 4.3 3.2 3.7 8.4 2.7 4.2 4.7 1.9 2.7 1.5 8.7 8.6 7.9 10.1 0.4 16.4 17.3 2.0 8.4 8.2 6.3 0.0 9.7 9.3 1.5 0.8 5.0 12.4 8.2 8.2 1.6 9.8 1.8 7.2 0.8 7.2 10.3 0.4 2.6 5.2 26.7 10.0 5.8 4.5 23.3 3.1 4.0 3.8 31.7 7.1 7.4 59.2 27.6 34.9 7.2 6.4 10.1 6.8 1.6 4.5 5.4 5.1 4.6 DMRT2 ENSG00000173253 "Doublesex and mab-3 related transcription factor 2" Q9Y5R5 9 1049858-1057552 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 41.2;lymphoid tissue: 20.9;parathyroid gland: 46.4" "Cell type enhanced" "Detected in some" "Distal tubular cells: 115.4;Ionocytes: 46.8;Skeletal myocytes: 22.7" "Group enriched" "Detected in many" 4 "lung cancer: 3.0;renal cancer: 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 3.8;RH-30: 5.0;RPMI-8226: 19.4;SK-MEL-30: 5.2;THP-1: 3.6;WM-115: 3.6" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" "HPA003498, HPA029297" Uncertain Approved "Nucleoplasm,Nucleoli,Vesicles,Centriolar satellite" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli" "Vesicles, Centriolar satellite" "HPA003498: , HPA029297: AB_10600905" "unprognostic (5.67e-2)" "unprognostic (2.20e-3)" "unprognostic (3.24e-2)" "unprognostic (8.88e-2)" "unprognostic (1.32e-1)" "unprognostic (7.10e-2)" "unprognostic (1.46e-1)" "unprognostic (1.65e-1)" "unprognostic (3.13e-1)" "unprognostic (7.43e-2)" "unprognostic (1.74e-1)" "unprognostic (1.43e-3)" "unprognostic (8.93e-2)" "unprognostic (8.62e-2)" "unprognostic (4.93e-2)" "unprognostic (1.27e-3)" 4.7 0.1 1.7 0.1 3.4 0.0 5.3 3.1 2.7 0.1 0.2 1.6 0.0 0.1 1.1 0.3 0.6 0.0 0.1 1.9 1.9 41.2 0.0 3.1 0.2 3.0 3.1 0.0 0.0 46.4 0.5 0.2 2.9 0.3 0.9 0.4 1.3 1.4 13.3 0.3 0.1 0.0 1.7 0.0 0.0 0.8 2.8 20.9 0.1 2.5 0.1 0.0 0.2 8.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 3.8 0.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.0 19.4 0.0 0.8 2.9 0.0 0.0 0.0 5.2 0.3 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.4 3.1 2.7 1.9 1.9 3.0 3.1 2.9 1.7 2.8 8.5 0.5 0.0 0.0 0.3 0.2 0.5 0.6 1.8 0.0 0.1 0.1 0.3 0.5 0.0 0.5 0.0 0.0 0.1 0.1 1.8 115.4 0.0 4.3 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 4.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 1.0 46.8 0.0 1.1 0.4 0.6 0.2 3.6 0.0 0.0 0.3 0.0 0.5 11.1 0.0 1.9 0.0 0.4 0.2 0.0 0.4 0.6 2.4 0.0 22.7 0.7 4.0 3.0 0.2 0.1 0.1 0.1 0.0 1.8 0.4 DMRTA1 ENSG00000176399 "DMRT like family A1" Q5VZB9 9 22446824-22455740 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 8.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 19.4;Distal tubular cells: 15.6;Glandular and luminal cells: 14.5;Hepatocytes: 30.8;Proximal tubular cells: 29.2;Squamous epithelial cells: 26.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 6.3;hTERT-RPE1: 7.4;LHCN-M2: 2.9;RPTEC TERT1: 3.0" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.2" "HPA044764, HPA062253" Uncertain Approved Vesicles NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "HPA044764: AB_10959788, HPA062253: AB_2684726" "unprognostic (1.47e-1)" "unprognostic (2.48e-2)" "unprognostic (2.86e-1)" "unprognostic (7.74e-4)" "unprognostic (3.81e-2)" "unprognostic (2.67e-3)" "unprognostic (4.36e-2)" "unprognostic (2.36e-2)" "unprognostic (1.28e-1)" "unprognostic (9.64e-2)" "unprognostic (3.65e-3)" "unprognostic (2.92e-1)" "prognostic favorable (1.14e-6)" "unprognostic (8.58e-2)" "unprognostic (1.13e-1)" "unprognostic (1.61e-1)" "unprognostic (8.53e-3)" 1.8 0.0 0.4 0.2 0.4 0.0 0.4 0.3 0.3 1.6 2.4 0.4 0.6 0.3 1.2 1.7 0.3 0.9 0.3 0.6 0.3 3.4 8.4 0.9 0.4 0.4 1.6 0.2 1.4 2.2 0.7 0.0 0.4 1.4 0.3 0.1 3.5 0.4 0.7 0.2 0.5 0.1 0.4 0.2 2.0 0.1 0.7 0.5 1.8 1.1 0.8 0.4 0.1 0.4 0.2 0.3 0.0 0.0 0.2 0.1 0.1 0.0 6.3 0.2 0.2 0.0 0.0 0.0 1.3 0.0 0.1 0.2 1.2 1.7 0.2 0.0 0.4 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.4 1.1 7.4 0.4 0.0 0.0 2.3 2.9 0.6 0.0 0.0 1.2 0.3 2.1 0.0 0.1 0.9 3.0 0.0 0.1 0.0 0.8 0.5 1.4 1.4 0.0 0.0 2.1 0.0 2.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.3 0.3 0.6 0.3 0.4 1.6 0.4 0.4 0.7 0.4 0.1 0.0 2.7 2.0 0.1 0.0 4.8 7.2 19.4 0.5 1.9 1.0 1.9 5.7 5.6 5.5 0.0 0.0 0.0 1.1 15.6 6.9 0.1 10.7 1.4 0.3 2.4 0.0 0.0 6.7 0.0 0.8 10.2 14.5 0.0 0.6 0.0 30.8 0.3 0.0 0.0 0.7 8.2 0.3 0.3 0.1 0.3 0.4 0.0 1.0 0.0 5.4 0.0 0.0 0.0 7.8 0.2 0.0 0.1 6.3 4.1 29.2 5.9 0.1 0.0 2.9 0.6 0.2 1.2 26.5 0.4 0.1 0.3 0.0 1.9 8.2 DNAJA3 "hTid-1, TID1" ENSG00000103423 "DnaJ heat shock protein family (Hsp40) member A3" Q96EY1 16 4425805-4456775 "Predicted intracellular proteins" Apoptosis Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016095, HPA040875, HPA044229" Approved Supported Vesicles,Mitochondria NA NA 16000 "Cluster 22: NK-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria Vesicles "CAB016095: AB_668801, HPA040875: AB_2677183, HPA044229: AB_2678865" "unprognostic (5.65e-2)" "unprognostic (1.34e-1)" "unprognostic (2.86e-3)" "unprognostic (2.91e-2)" "unprognostic (4.17e-1)" "unprognostic (5.18e-2)" "unprognostic (1.60e-1)" "unprognostic (1.38e-1)" "unprognostic (2.06e-1)" "unprognostic (3.16e-3)" "unprognostic (1.55e-1)" "unprognostic (3.27e-2)" "prognostic favorable (1.79e-4)" "unprognostic (4.17e-2)" "unprognostic (1.57e-1)" "unprognostic (1.34e-1)" "unprognostic (1.92e-1)" 18.9 44.3 15.7 11.8 16.3 6.4 18.3 17.5 18.7 19.9 15.3 25.2 17.5 18.6 6.8 27.8 18.0 8.1 43.6 16.0 16.8 26.7 65.7 15.8 13.3 16.5 16.1 20.7 26.5 23.9 20.2 12.3 17.2 18.7 12.6 8.7 20.2 12.4 90.5 22.7 21.2 10.4 16.6 19.3 23.9 23.6 17.5 11.5 18.7 48.3 11.9 23.8 20.5 16.8 26.4 53.7 16.1 33.1 20.5 18.8 34.6 34.2 22.9 45.1 36.1 40.2 38.7 50.2 32.9 20.3 31.3 38.4 55.7 39.7 24.8 42.2 35.8 25.4 48.8 40.4 50.8 47.5 24.4 22.6 46.6 40.0 66.1 20.5 20.4 36.7 63.1 39.7 27.8 60.9 39.6 33.8 35.6 48.2 43.2 51.5 27.6 92.7 32.5 28.0 43.7 17.3 38.2 77.6 62.0 13.7 46.7 38.3 22.2 35.8 24.5 80.1 44.4 38.5 56.6 69.7 17.9 45.0 39.8 1.4 5.3 3.2 10.3 8.7 12.4 12.1 9.6 9.8 7.6 10.0 12.9 10.4 0.8 11.1 6.9 5.4 10.8 10.5 15.7 16.3 17.5 18.7 16.0 16.8 16.5 16.1 17.2 16.6 17.5 16.8 10.9 12.8 8.1 11.4 23.7 15.7 18.5 12.6 25.0 23.0 14.8 10.8 36.3 14.3 13.0 25.8 10.4 42.8 8.2 17.9 45.0 21.8 62.6 8.9 13.5 13.3 17.5 18.7 19.4 12.2 34.3 13.6 18.8 10.0 12.7 17.9 8.9 46.1 16.6 23.5 20.4 17.5 16.2 10.1 7.0 30.5 19.3 10.0 21.4 6.5 15.2 18.5 16.5 10.6 15.2 13.9 15.5 22.2 19.9 28.9 21.5 25.9 9.2 23.2 13.1 14.2 14.2 50.5 33.7 23.5 16.9 28.5 17.5 29.8 32.7 16.7 DNAJC13 "KIAA0678, RME8" ENSG00000138246 "DnaJ heat shock protein family (Hsp40) member C13" O75165 3 132417502-132539032 "Human disease related genes, Predicted membrane proteins" "Protein transport, Transport" Chaperone "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036923, HPA036924" Approved Supported Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" Vesicles Cytosol "HPA036923: AB_10672480, HPA036924: AB_2675386" "unprognostic (3.35e-3)" "unprognostic (7.47e-2)" "unprognostic (9.16e-2)" "unprognostic (1.20e-2)" "unprognostic (9.71e-2)" "unprognostic (4.92e-2)" "prognostic unfavorable (7.49e-4)" "unprognostic (3.68e-2)" "unprognostic (3.38e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (8.36e-4)" "unprognostic (1.92e-1)" "unprognostic (4.81e-3)" "unprognostic (2.15e-1)" "unprognostic (1.71e-1)" "unprognostic (2.34e-2)" "unprognostic (1.22e-1)" 11.7 9.4 5.9 12.4 6.5 15.5 11.4 6.0 6.3 12.9 8.2 14.4 10.9 13.8 11.7 10.7 9.9 9.9 12.9 5.9 6.9 16.0 9.8 11.3 11.0 7.7 6.9 11.7 6.8 12.6 5.9 15.4 7.1 10.8 14.3 10.7 9.1 12.1 12.5 9.8 10.4 16.7 6.3 12.2 9.7 7.8 7.5 12.0 15.7 14.2 10.6 12.4 10.3 7.8 31.0 18.0 22.2 10.9 54.3 46.7 13.7 32.3 62.5 31.4 33.8 20.4 18.2 15.7 20.5 46.3 41.1 24.1 22.1 24.3 43.5 18.3 6.4 20.6 17.1 13.6 27.6 21.1 18.3 34.2 16.4 28.5 35.1 22.7 44.6 26.0 11.4 25.6 43.7 24.1 16.8 9.1 12.7 26.7 15.8 15.9 16.5 13.0 27.7 32.4 7.9 11.9 31.6 16.7 36.1 19.0 24.7 17.8 40.9 34.7 17.8 33.3 13.9 14.8 15.7 21.5 36.8 13.6 25.2 2.0 2.6 0.4 0.8 2.2 0.7 1.0 0.9 0.7 2.8 0.4 0.6 0.8 0.5 0.7 4.0 1.4 0.4 0.8 5.9 6.5 6.0 6.3 5.9 6.9 7.7 6.9 7.1 6.3 7.5 7.8 16.8 12.8 21.9 45.7 14.4 6.6 7.3 7.3 6.8 10.8 8.9 7.2 47.2 8.6 11.3 12.9 33.3 7.9 13.2 21.5 1.9 9.0 1.7 10.3 31.3 17.1 14.4 12.8 48.7 9.1 7.7 20.2 16.8 18.7 12.0 18.9 13.2 8.5 20.5 67.3 48.7 12.5 0.0 34.2 9.2 3.6 15.2 26.5 28.4 60.0 25.1 13.3 6.2 46.8 64.7 11.7 12.5 21.4 13.9 10.5 17.0 18.7 13.1 11.5 6.6 22.3 19.7 5.3 13.7 15.4 7.5 5.1 10.8 22.5 13.4 11.0 DNAJC16 KIAA0962 ENSG00000116138 "DnaJ heat shock protein family (Hsp40) member C16" Q9Y2G8 1 15526813-15592379 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043643 Approved Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA043643: AB_10796794" "unprognostic (1.77e-1)" "unprognostic (4.95e-2)" "prognostic favorable (6.77e-4)" "unprognostic (4.52e-2)" "unprognostic (5.51e-2)" "unprognostic (2.05e-2)" "unprognostic (1.91e-2)" "unprognostic (2.15e-1)" "unprognostic (1.29e-1)" "unprognostic (4.28e-2)" "unprognostic (2.35e-2)" "unprognostic (3.74e-2)" "prognostic favorable (7.24e-4)" "unprognostic (3.67e-2)" "unprognostic (3.74e-1)" "unprognostic (5.38e-2)" "unprognostic (4.70e-2)" 4.9 5.2 4.5 5.5 5.3 2.2 6.5 5.4 6.5 5.0 7.8 6.0 6.5 5.6 7.6 5.4 6.8 4.5 5.1 5.3 4.9 11.5 10.1 4.8 6.2 4.2 4.4 5.7 6.4 10.0 5.3 5.8 4.8 5.5 5.9 9.0 7.0 4.8 11.9 5.6 5.8 6.3 4.1 5.7 5.4 6.3 5.0 5.1 7.4 6.3 6.4 5.2 4.6 6.4 8.8 8.7 6.7 12.4 18.0 14.5 6.3 10.4 10.7 10.2 10.9 7.1 12.7 7.6 6.8 10.3 13.3 10.7 8.3 9.2 14.3 9.0 4.0 7.8 9.6 12.2 17.8 12.2 8.7 10.5 10.6 16.4 9.2 12.7 11.6 6.3 16.9 6.7 11.8 3.6 6.2 6.2 6.5 7.9 5.6 7.3 8.6 8.5 12.6 6.0 7.5 7.0 10.6 10.1 9.0 9.6 6.3 4.8 15.7 17.9 6.4 16.7 5.7 9.1 13.8 6.6 11.1 6.9 8.7 2.0 2.1 1.5 2.6 2.0 3.9 3.4 2.8 2.4 2.1 3.1 3.5 3.0 1.1 1.6 1.5 1.9 2.8 1.9 4.5 5.3 5.4 6.5 5.3 4.9 4.2 4.4 4.8 4.1 5.0 6.4 11.6 0.0 8.7 25.5 12.4 5.1 4.3 13.8 9.6 14.9 16.1 8.4 16.9 22.8 14.9 25.8 22.9 12.8 11.5 13.7 1.9 9.1 11.6 25.5 19.0 12.0 11.5 4.6 33.5 6.9 7.7 10.5 11.7 17.6 8.2 14.0 16.4 20.5 10.9 18.5 28.6 9.7 18.3 20.6 5.5 5.8 12.5 9.5 7.2 17.8 11.4 12.8 12.3 19.1 28.8 9.3 7.5 11.3 6.8 12.6 10.6 19.0 37.5 16.0 6.6 11.7 7.8 24.7 15.7 13.0 5.8 22.0 7.1 11.4 13.4 8.2 DNAJC22 "FLJ13236, wus" ENSG00000178401 "DnaJ heat shock protein family (Hsp40) member C22" Q8N4W6 12 49346888-49357546 "Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 24.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 47.1;Distal enterocytes: 36.8;Exocrine glandular cells: 42.9;Hepatocytes: 44.6;Intestinal goblet cells: 26.9;Pancreatic endocrine cells: 27.6;Paneth cells: 26.2;Proximal enterocytes: 59.6;Undifferentiated cells: 26.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 10.5;CACO-2: 19.1;EFO-21: 17.2;MCF7: 18.8;OE19: 18.6" "Region enhanced" "Detected in single" "midbrain: 1.2" "Low region specificity" "Detected in all" HPA039953 Approved Vesicles NA NA "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA039953: AB_2676770" "unprognostic (5.23e-2)" "unprognostic (1.24e-1)" "unprognostic (9.01e-2)" "prognostic favorable (4.56e-5)" "unprognostic (4.77e-3)" "unprognostic (2.74e-1)" "unprognostic (1.28e-1)" "unprognostic (4.05e-2)" "prognostic unfavorable (7.54e-4)" "unprognostic (6.14e-2)" "unprognostic (1.23e-2)" "unprognostic (2.49e-1)" "unprognostic (1.49e-2)" "unprognostic (3.18e-2)" "unprognostic (9.35e-2)" "unprognostic (1.58e-1)" "unprognostic (3.83e-2)" 1.2 0.2 0.5 0.4 0.7 0.2 0.3 1.5 0.8 1.1 0.6 4.0 5.6 0.6 0.3 0.0 0.7 3.1 0.1 0.5 0.5 3.7 24.1 0.1 0.1 1.7 1.4 0.0 5.6 2.0 0.2 0.2 1.8 0.2 2.2 0.2 1.4 0.1 0.0 0.4 5.0 0.2 0.7 0.2 3.0 0.6 0.8 0.0 4.4 0.0 0.0 0.1 0.7 1.1 0.9 5.6 0.0 10.5 0.0 0.0 2.4 0.0 1.9 0.5 1.3 19.1 4.0 0.0 17.2 0.5 0.6 0.2 1.2 0.0 1.5 0.0 3.5 0.2 0.4 6.3 1.1 0.1 1.2 0.2 0.1 0.6 0.1 2.8 0.5 0.1 0.1 0.2 0.6 18.8 0.0 0.1 0.1 18.6 5.8 0.0 3.6 0.1 0.3 0.1 2.6 0.6 0.1 0.3 2.4 0.1 6.7 0.0 0.2 0.6 2.1 0.1 0.6 0.0 0.0 0.0 1.7 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.7 1.5 0.8 0.5 0.5 1.7 1.4 1.8 0.7 0.8 1.1 0.2 0.0 1.1 1.0 0.3 0.6 1.5 3.0 0.0 0.3 5.9 3.7 0.5 47.1 2.0 1.8 0.0 0.1 0.3 36.8 0.0 16.0 4.1 6.2 4.5 0.6 21.0 0.0 0.5 42.9 0.3 3.8 10.2 5.9 1.3 4.7 1.4 44.6 0.1 3.3 0.2 26.9 0.0 0.8 0.4 1.9 0.0 0.4 3.6 0.0 0.6 0.6 0.0 0.0 5.7 27.6 26.2 0.7 0.0 0.7 59.6 18.6 5.7 0.5 0.0 0.5 2.1 1.9 1.9 0.0 0.3 0.4 0.5 1.0 26.2 0.4 DNAJC5 "CLN4, DNAJC5A, FLJ00118, FLJ13070" ENSG00000101152 "DnaJ heat shock protein family (Hsp40) member C5" Q9H3Z4 20 63895126-63936031 "Disease related genes, Human disease related genes, Predicted membrane proteins" Chaperone "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 123.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012139, HPA012737, HPA013154" Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus, Plasma membrane" Vesicles "HPA012139: , HPA012737: AB_1847293, HPA013154: AB_1847292" "unprognostic (9.96e-3)" "unprognostic (2.75e-1)" "unprognostic (3.91e-1)" "unprognostic (3.61e-2)" "unprognostic (1.65e-1)" "unprognostic (3.47e-2)" "prognostic unfavorable (8.82e-6)" "unprognostic (3.04e-2)" "unprognostic (2.73e-1)" "unprognostic (2.65e-2)" "unprognostic (1.78e-3)" "unprognostic (1.51e-1)" "prognostic favorable (7.70e-6)" "unprognostic (2.24e-2)" "unprognostic (3.54e-2)" "unprognostic (4.28e-3)" "unprognostic (1.08e-2)" 12.6 22.1 30.8 10.7 33.0 16.9 11.1 10.2 39.1 11.4 2.1 17.6 11.5 12.1 5.7 42.0 11.6 7.4 25.8 36.2 31.0 17.7 12.8 18.0 9.9 27.9 23.9 8.8 22.7 21.2 28.5 8.4 30.4 16.7 6.9 28.1 16.2 11.5 14.5 19.2 17.5 8.6 13.8 22.2 20.8 10.7 26.8 8.4 16.8 9.5 8.5 13.4 16.9 25.7 25.2 23.7 19.8 18.8 19.4 15.9 14.6 28.6 27.4 49.4 23.8 52.7 30.2 9.8 31.6 28.2 22.7 36.4 15.9 53.6 16.0 8.2 11.3 19.3 17.4 25.8 18.1 19.2 43.5 18.0 39.9 22.9 11.7 19.1 24.2 16.5 19.2 8.9 22.6 17.3 21.1 30.9 7.1 21.0 26.5 21.0 10.9 10.7 16.4 22.6 21.4 13.9 30.8 48.7 17.8 11.6 23.5 75.9 43.7 42.6 14.4 20.4 21.5 11.1 5.6 13.6 42.9 25.3 25.4 0.7 3.2 2.6 3.2 3.7 1.8 1.6 1.8 2.7 2.5 1.4 2.5 2.5 3.1 1.5 3.1 3.9 3.1 2.6 30.8 33.0 10.2 39.1 36.2 31.0 27.9 23.9 30.4 13.8 26.8 25.7 12.8 6.4 17.8 19.2 10.4 20.8 18.5 25.5 20.5 60.7 17.4 14.1 31.7 14.3 23.2 23.9 62.6 18.5 19.1 71.7 13.7 20.5 48.9 23.9 8.5 18.7 32.4 10.3 37.1 37.6 18.4 12.4 27.0 23.5 1.3 12.1 23.9 27.8 43.5 79.1 38.8 33.3 14.2 51.0 24.8 123.5 7.2 31.4 14.2 25.3 36.9 27.9 22.6 19.1 26.2 59.0 41.1 12.4 17.3 39.5 62.0 22.9 29.4 47.0 13.1 9.0 13.1 13.5 13.2 28.0 22.9 30.2 15.0 13.3 28.4 64.5 DNASE1 DNL1 ENSG00000213918 "Deoxyribonuclease 1" P24855 16 3611728-3680143 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Actin-binding, Endonuclease, Hydrolase, Nuclease" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 34.5;kidney: 34.2" "Cell type enriched" "Detected in many" 11 "Proximal enterocytes: 715.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA010703 Enhanced Supported Vesicles "Secreted in other tissues" NA NA 420000 "Cluster 49: Eosinophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA010703: AB_10600806" "unprognostic (5.18e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-1)" "unprognostic (1.74e-1)" "unprognostic (2.38e-1)" "unprognostic (1.90e-2)" "unprognostic (3.73e-2)" "unprognostic (3.82e-1)" "unprognostic (3.20e-1)" "unprognostic (9.91e-2)" "unprognostic (1.69e-3)" "unprognostic (5.37e-2)" "unprognostic (1.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.74e-1)" "unprognostic (1.45e-1)" "prognostic favorable (1.14e-4)" 4.6 5.0 5.1 6.6 5.6 4.3 4.6 13.4 6.4 9.8 6.9 6.1 29.7 5.2 5.0 7.1 6.8 2.7 5.5 5.8 4.9 34.2 5.9 4.9 10.0 6.0 5.2 7.5 23.6 2.7 16.3 4.2 6.6 11.6 5.0 4.4 4.9 2.5 3.7 7.8 34.5 2.7 3.2 9.2 11.2 9.2 5.8 9.4 7.4 1.3 8.7 6.0 8.5 9.7 2.9 6.5 11.4 5.9 3.3 2.8 5.2 4.7 0.8 3.7 5.3 8.0 6.9 12.3 3.6 0.7 7.8 4.8 4.2 1.3 3.9 5.5 6.4 4.4 11.3 5.4 1.7 2.9 9.6 2.3 4.8 5.0 1.2 5.8 2.5 10.3 11.2 5.0 3.2 12.3 6.3 13.6 6.9 8.7 3.6 14.9 5.3 5.7 3.1 2.5 8.1 7.6 3.5 10.5 1.9 5.7 10.4 7.7 3.4 6.8 5.0 4.3 2.5 4.8 7.5 21.4 1.7 5.7 6.6 2.7 1.1 3.2 1.5 0.7 1.0 1.4 1.2 1.3 0.6 2.1 1.3 1.8 5.0 1.0 0.7 1.1 1.4 0.5 5.1 5.6 13.4 6.4 5.8 4.9 6.0 5.2 6.6 3.2 5.8 9.7 4.9 9.6 10.3 27.1 9.1 2.7 8.6 3.1 10.8 27.3 5.5 4.8 6.0 4.3 9.7 16.5 22.9 8.6 9.3 11.8 56.7 5.3 19.3 9.8 10.0 7.7 14.3 7.6 20.5 11.0 4.1 7.4 13.3 8.4 2.5 23.3 7.5 1.8 3.9 25.2 22.0 38.6 20.3 5.0 4.2 52.4 8.4 4.4 1.8 15.9 13.2 8.6 30.9 22.1 20.6 5.3 61.4 7.9 7.2 12.4 715.5 2.4 9.1 17.9 0.0 13.6 6.3 28.5 24.5 5.8 3.8 6.2 12.2 10.4 33.4 6.3 DNM1L "DRP1, DVLP, DYMPLE, HDYNIV, VPS1" ENSG00000087470 "Dynamin 1 like" O00429 12 32679200-32745650 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Biological rhythms, Endocytosis, Necrosis" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009952, HPA039324" Approved Enhanced Vesicles,Cytosol NA NA 2000000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 46: Photoreceptor cells - Phototransduction" Cytosol Vesicles "CAB009952: AB_2093533, HPA039324: AB_2676443" "unprognostic (2.64e-2)" "unprognostic (2.94e-1)" "unprognostic (1.10e-3)" "unprognostic (1.12e-1)" "unprognostic (5.09e-1)" "unprognostic (4.06e-2)" "prognostic unfavorable (6.27e-6)" "unprognostic (8.68e-2)" "unprognostic (2.25e-2)" "unprognostic (1.04e-2)" "unprognostic (1.71e-1)" "unprognostic (2.63e-1)" "unprognostic (4.06e-1)" "unprognostic (1.00e-1)" "unprognostic (8.17e-2)" "unprognostic (7.48e-2)" "unprognostic (1.57e-2)" 23.2 23.2 25.3 23.5 27.5 40.0 21.1 27.7 32.3 18.4 15.7 24.0 18.6 23.6 23.9 28.6 19.8 17.5 38.9 28.4 26.1 27.9 14.2 16.7 20.9 22.5 22.0 20.0 13.5 40.5 25.3 23.9 23.6 27.0 22.7 44.9 16.0 28.7 43.8 18.3 16.8 32.0 22.2 18.8 17.3 36.0 21.6 21.4 22.4 57.2 24.8 29.9 18.5 26.6 66.8 62.3 64.3 68.3 51.2 52.7 123.2 72.0 55.4 67.2 61.7 80.6 48.0 87.3 50.0 65.8 66.9 57.8 69.2 80.3 79.3 46.6 57.6 102.3 57.2 48.2 41.7 72.5 50.1 48.6 37.4 70.7 66.1 63.5 81.1 41.4 74.4 37.5 75.3 21.7 29.1 61.7 138.2 41.0 30.8 48.6 125.0 61.5 56.5 79.1 57.1 59.3 76.3 51.8 56.7 129.4 59.7 49.0 74.0 57.3 54.4 135.3 68.2 26.1 75.8 86.3 55.6 47.0 43.5 7.4 10.0 3.2 5.6 15.6 6.9 7.0 6.2 6.1 18.8 6.0 7.3 8.4 1.8 8.1 15.6 5.6 7.3 7.9 25.3 27.5 27.7 32.3 28.4 26.1 22.5 22.0 23.6 22.2 21.6 26.6 42.5 38.5 38.4 82.6 36.0 30.0 34.7 28.0 44.3 80.9 32.5 29.2 82.8 20.0 33.3 25.8 131.3 30.0 53.8 26.7 31.3 34.8 63.9 38.8 55.8 42.0 30.5 28.4 139.4 25.1 63.7 41.0 23.9 59.4 50.7 48.8 26.4 16.0 30.8 126.2 150.0 24.9 34.6 27.5 30.7 78.0 26.8 43.3 14.2 44.0 45.6 59.0 34.0 99.5 121.7 45.7 14.4 30.5 48.5 42.8 11.4 23.3 22.8 164.8 19.7 55.0 55.5 79.3 52.3 39.6 27.6 36.0 42.2 26.0 31.5 36.4 DOLPP1 LSFR2 ENSG00000167130 "Dolichyldiphosphatase 1" Q86YN1 9 129081111-129090438 "Enzymes, Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 29.1;Proximal enterocytes: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019179 Approved Approved "Vesicles,Intermediate filaments" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 45: Enterocytes - Digestion" Vesicles "Intermediate filaments" "HPA019179: AB_1847827" "unprognostic (1.32e-2)" "unprognostic (1.23e-1)" "unprognostic (3.89e-1)" "unprognostic (6.12e-3)" "unprognostic (3.11e-1)" "unprognostic (2.63e-2)" "unprognostic (3.18e-1)" "unprognostic (3.10e-2)" "unprognostic (6.96e-2)" "unprognostic (7.12e-2)" "unprognostic (1.65e-1)" "unprognostic (4.37e-3)" "unprognostic (7.59e-3)" "unprognostic (2.38e-2)" "unprognostic (1.35e-1)" "unprognostic (4.69e-2)" "unprognostic (5.34e-2)" 5.6 11.4 12.2 6.3 13.4 8.1 5.8 13.0 13.8 6.6 8.7 15.5 26.2 5.3 6.0 19.2 5.5 5.8 4.6 12.1 12.5 6.0 22.4 5.0 6.6 13.3 13.4 5.2 10.4 8.7 6.2 7.6 14.3 8.5 12.5 3.8 9.9 4.7 4.9 10.5 22.6 5.3 13.1 7.8 10.8 8.1 13.5 10.1 5.4 4.8 6.6 6.0 8.3 15.2 8.7 33.6 31.4 29.6 10.3 9.1 36.2 20.9 12.2 39.3 22.0 42.9 28.4 16.7 18.2 13.0 30.2 61.8 32.6 17.8 16.6 19.9 20.6 22.0 22.3 34.5 18.8 23.0 26.4 9.5 24.4 25.5 20.3 8.9 17.5 30.7 37.3 16.2 11.4 44.7 26.5 24.8 27.4 64.7 28.2 30.8 25.3 31.2 14.2 14.1 35.9 24.2 27.1 24.1 9.4 18.4 44.8 15.0 14.5 33.5 16.4 33.4 29.0 20.3 41.6 25.3 15.3 4.6 22.8 7.9 8.2 12.6 10.2 10.5 25.2 11.4 12.6 12.6 10.5 7.7 12.5 11.9 1.7 11.2 11.0 15.8 13.6 8.9 12.2 13.4 13.0 13.8 12.1 12.5 13.3 13.4 14.3 13.1 13.5 15.2 3.1 6.4 6.3 4.2 3.9 2.3 3.0 6.9 1.2 3.7 7.3 5.2 2.1 10.0 6.3 1.8 6.2 18.8 2.8 29.1 1.9 7.1 0.5 3.9 5.0 3.4 3.6 13.0 3.1 9.6 14.2 3.9 10.2 5.4 5.7 3.8 5.3 18.3 7.5 3.3 4.4 10.1 6.1 2.9 1.9 0.5 2.1 2.7 5.4 1.0 4.2 8.6 6.2 3.5 6.4 6.6 16.2 4.1 6.7 3.8 42.0 4.1 3.2 3.7 0.0 3.1 4.0 6.3 9.7 11.0 4.0 16.4 4.4 8.1 13.5 4.1 DOP1A "dJ202D23.2, DOPEY1, KIAA1117" ENSG00000083097 "DOP1 leucine zipper like protein A" Q5JWR5 6 83067666-83171350 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 5.7;Cardiomyocytes: 9.8;Cytotrophoblasts: 4.8;dendritic cells: 5.9;Hofbauer cells: 4.1;Plasma cells: 3.8;Syncytiotrophoblasts: 3.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027902, HPA027904" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Vesicles "HPA027902: AB_10600003, HPA027904: AB_10600877" "unprognostic (7.18e-2)" "unprognostic (3.91e-1)" "unprognostic (6.11e-2)" "unprognostic (6.05e-3)" "unprognostic (8.21e-3)" "unprognostic (1.36e-2)" "unprognostic (3.32e-1)" "unprognostic (1.02e-2)" "unprognostic (2.84e-1)" "unprognostic (2.47e-1)" "prognostic favorable (7.36e-4)" "unprognostic (2.13e-1)" "unprognostic (1.20e-1)" "unprognostic (1.45e-1)" "unprognostic (1.12e-1)" "unprognostic (1.32e-1)" "unprognostic (1.17e-1)" 5.2 4.9 5.0 6.2 5.7 4.9 10.9 8.7 6.4 8.9 3.5 8.0 7.9 10.4 7.4 7.1 9.4 7.2 9.0 5.1 4.2 6.9 6.2 6.8 7.2 3.8 3.7 13.8 9.1 11.6 7.7 6.0 3.7 9.6 8.8 24.0 9.5 10.7 6.3 13.6 8.9 7.5 5.0 8.2 7.2 12.7 4.1 10.6 13.6 9.4 7.5 6.2 5.0 11.0 4.2 3.0 9.8 8.9 8.7 9.1 4.6 7.0 5.9 4.7 6.8 6.4 1.0 8.2 4.9 7.7 5.9 5.5 10.0 7.6 5.9 7.2 11.3 6.8 4.2 2.4 4.7 10.1 6.9 7.3 10.4 6.6 17.0 6.2 7.0 12.6 14.4 5.9 5.1 3.9 3.0 4.5 2.0 3.1 6.1 8.2 7.4 3.0 6.1 11.7 17.6 3.2 5.2 3.3 1.3 7.0 5.3 5.7 11.8 5.9 2.1 6.0 5.5 7.3 5.7 4.6 3.2 4.6 4.7 0.0 0.3 0.4 0.5 0.4 0.4 0.6 0.4 1.1 0.7 0.4 0.8 0.4 0.0 0.4 0.3 0.3 0.4 0.4 5.0 5.7 8.7 6.4 5.1 4.2 3.8 3.7 3.7 5.0 4.1 11.0 5.7 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 4.8 5.9 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 3.4 0.8 0.0 0.0 0.0 DPP7 "DPP2, DPPII" ENSG00000176978 "Dipeptidyl peptidase 7" Q9UHL4 9 137110546-137115177 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aminopeptidase, Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 997.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 232.0;THP-1: 218.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021282, CAB025541, HPA059381" Enhanced Supported "Golgi apparatus,Vesicles" "Secreted - unknown location" NA NA 1600000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "CAB025541: , HPA021282: AB_1847673, HPA059381: AB_2683999" "unprognostic (1.15e-1)" "unprognostic (5.54e-2)" "prognostic unfavorable (6.07e-6)" "unprognostic (6.78e-3)" "unprognostic (1.25e-1)" "unprognostic (8.33e-2)" "unprognostic (7.49e-2)" "unprognostic (6.10e-2)" "unprognostic (2.28e-2)" "unprognostic (5.71e-3)" "prognostic favorable (8.31e-5)" "unprognostic (7.99e-2)" "unprognostic (1.46e-2)" "unprognostic (2.56e-2)" "unprognostic (1.72e-1)" "unprognostic (2.15e-1)" "unprognostic (1.02e-1)" 60.2 98.8 42.1 28.0 43.2 45.8 56.8 43.4 64.9 45.4 83.6 65.3 28.4 46.3 16.7 46.0 53.6 31.3 116.4 43.8 52.0 58.7 70.0 57.3 41.7 53.4 48.0 37.7 82.8 54.3 112.3 26.7 45.7 81.1 7.3 8.0 92.3 46.2 52.8 56.6 51.7 12.8 45.6 79.0 69.4 75.3 48.3 19.8 83.7 21.4 14.4 59.3 48.0 49.2 28.0 43.1 3.5 3.6 51.1 40.5 5.7 42.2 66.2 26.6 17.4 41.0 22.2 56.2 44.4 27.2 1.2 60.3 30.7 8.2 1.3 54.8 2.1 26.4 63.6 1.3 113.5 69.1 135.5 50.0 31.7 11.6 24.1 38.3 35.1 65.8 57.5 41.2 18.0 76.4 35.7 65.7 14.8 99.9 42.8 52.8 0.5 232.0 43.3 30.5 67.7 46.7 47.8 122.6 118.9 0.8 43.5 218.1 44.1 67.4 23.5 43.4 29.5 51.7 31.8 14.9 80.9 41.1 31.1 40.2 194.8 59.2 148.8 176.2 151.8 86.6 131.4 127.9 190.6 83.4 117.1 106.2 12.0 95.0 110.6 276.6 173.6 204.1 42.1 43.2 43.4 64.9 43.8 52.0 53.4 48.0 45.7 45.6 48.3 49.2 80.5 54.5 80.9 54.9 96.8 67.0 103.2 109.2 59.7 74.5 90.3 82.2 66.5 94.4 76.8 53.3 35.5 55.2 129.2 28.2 37.2 121.0 288.7 35.9 40.7 58.2 88.1 35.9 31.4 68.1 115.3 97.2 33.6 47.3 74.3 178.7 64.6 77.1 315.7 121.1 27.9 32.3 107.8 171.7 106.2 997.8 155.4 150.1 167.2 9.4 165.5 123.9 122.6 16.6 26.4 58.2 54.3 169.2 190.2 108.5 97.3 84.9 75.4 83.6 52.6 57.4 58.4 106.2 46.2 47.3 64.9 51.4 115.4 19.0 43.1 90.4 DPT ENSG00000143196 Dermatopontin Q07507 1 168695468-168729206 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 424.7" "Group enriched" "Detected in many" 5 "Fibroblasts: 457.5;Leydig cells: 231.8;Peritubular cells: 123.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "ASC diff: 143.3;fHDF/TERT166: 59.9" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "midbrain: 1.0" HPA065548 Approved Vesicles "Secreted to extracellular matrix" NA NA 610000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA065548: AB_2685511" "unprognostic (1.49e-1)" "unprognostic (7.62e-2)" "unprognostic (5.66e-2)" "unprognostic (4.39e-2)" "unprognostic (4.64e-2)" "unprognostic (3.78e-3)" "unprognostic (4.09e-2)" "unprognostic (2.57e-1)" "unprognostic (1.48e-1)" "unprognostic (1.03e-2)" "unprognostic (8.88e-2)" "unprognostic (2.16e-2)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.12e-3)" "unprognostic (2.89e-2)" "unprognostic (1.09e-1)" "unprognostic (8.98e-3)" 334.6 39.6 0.4 28.6 0.5 0.0 251.3 0.5 1.0 177.6 0.5 424.7 18.8 63.2 60.8 86.0 129.1 78.0 241.4 0.5 0.4 13.2 29.0 48.6 58.6 0.5 0.4 30.3 84.8 4.9 2.1 37.5 0.6 55.2 58.2 0.0 72.0 52.7 37.1 39.2 94.2 138.5 0.5 0.9 108.5 15.4 0.5 48.0 75.0 209.3 70.1 103.3 166.9 0.7 0.0 0.0 0.0 0.0 143.3 0.6 0.2 0.1 6.7 7.2 7.4 0.0 0.0 0.0 0.0 59.9 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 4.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 7.6 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.5 1.0 0.5 0.4 0.5 0.4 0.6 0.5 0.5 0.7 18.7 3.2 1.7 0.3 0.3 31.9 0.1 0.0 1.8 0.0 2.2 2.3 7.4 0.0 0.6 0.0 0.0 0.6 0.4 0.1 0.0 0.1 1.2 0.3 10.7 6.9 0.0 0.0 4.8 0.2 0.8 457.5 3.1 0.2 0.0 0.0 8.9 0.0 0.6 0.0 3.4 0.0 0.0 0.0 45.6 4.4 231.8 4.0 39.2 1.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 123.8 0.5 0.5 0.0 0.1 0.0 0.0 0.0 24.4 18.5 0.5 0.3 3.1 32.0 0.4 5.0 2.2 0.0 0.6 DPY19L1 KIAA0877 ENSG00000173852 "Dpy-19 like C-mannosyltransferase 1" Q2PZI1 7 34928876-35038271 "Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 206.2;Excitatory neurons: 132.8;Late spermatids: 72.0;Oligodendrocytes: 95.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059139 Uncertain Approved Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 21: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA059139: AB_2683921" "unprognostic (4.66e-2)" "unprognostic (1.11e-3)" "unprognostic (8.53e-3)" "unprognostic (2.47e-3)" "unprognostic (2.50e-2)" "unprognostic (3.80e-3)" "unprognostic (2.02e-3)" "unprognostic (3.57e-2)" "unprognostic (1.14e-1)" "unprognostic (4.84e-2)" "prognostic unfavorable (2.99e-4)" "unprognostic (3.21e-1)" "unprognostic (1.88e-2)" "unprognostic (3.99e-1)" "unprognostic (2.69e-2)" "unprognostic (1.37e-1)" "unprognostic (4.12e-2)" 10.8 13.2 16.5 12.1 18.6 11.2 6.4 22.2 22.3 15.9 11.0 10.6 5.3 18.9 4.1 7.6 10.7 15.2 14.9 18.0 23.2 7.0 19.5 14.7 10.7 23.6 22.9 9.0 5.6 4.1 6.2 21.6 22.0 9.0 12.1 27.9 7.1 8.4 3.5 4.6 6.2 19.3 25.2 15.7 10.1 38.1 21.5 4.8 11.4 6.1 9.8 16.5 5.5 33.4 16.7 64.6 36.2 46.3 69.7 55.3 7.5 36.6 30.7 22.4 29.3 15.5 42.4 24.2 52.1 38.2 92.4 29.1 27.2 20.1 50.1 12.4 22.2 35.3 40.2 25.7 24.5 33.6 31.6 27.3 16.5 29.7 20.1 63.1 93.5 11.9 26.9 95.8 79.3 8.1 0.3 33.3 23.3 39.2 28.9 24.7 47.8 34.8 85.0 57.4 16.7 43.4 32.8 4.2 19.4 56.5 32.6 38.6 109.1 44.3 53.1 30.9 50.2 42.3 99.9 27.6 54.9 30.5 126.2 0.9 0.5 0.0 1.2 0.7 1.3 0.4 0.5 1.0 0.5 0.7 0.1 0.5 0.1 0.6 0.2 0.5 0.3 0.3 16.5 18.6 22.2 22.3 18.0 23.2 23.6 22.9 22.0 25.2 21.5 33.4 12.1 28.9 16.4 42.7 3.9 7.1 5.6 4.4 2.2 8.4 7.4 5.8 13.3 5.7 10.0 7.3 18.8 14.5 10.2 11.2 0.0 7.7 206.2 17.0 23.4 13.9 14.9 8.2 132.8 16.4 4.1 11.3 10.7 16.9 27.3 6.5 20.3 15.4 8.7 11.8 35.1 5.1 4.1 11.1 7.5 72.0 9.3 8.0 5.4 30.0 4.4 8.6 3.1 30.2 95.5 24.0 4.5 10.1 8.0 9.5 1.0 1.9 12.4 12.8 0.0 7.5 8.5 9.1 4.6 3.2 4.8 21.2 6.9 4.4 8.5 13.7 DPYSL4 "CRMP3, DRP-4, ULIP4" ENSG00000151640 "Dihydropyrimidinase like 4" O14531 10 132186948-132205759 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.9;heart muscle: 33.7;retina: 15.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 64.9;Cardiomyocytes: 20.1;Cone photoreceptor cells: 58.4;Horizontal cells: 33.7;Oligodendrocytes: 18.4" "Cancer enhanced" "Detected in many" "glioma: 13.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 53.2;AN3-CA: 70.0;SH-SY5Y: 72.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049066 Approved Approved Vesicles,Mitochondria NA NA "Cluster 32: T-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" "Vesicles, Mitochondria" "HPA049066: AB_2680619" "unprognostic (6.27e-2)" "unprognostic (2.07e-2)" "unprognostic (1.35e-1)" "unprognostic (1.81e-1)" "unprognostic (3.95e-1)" "unprognostic (5.99e-2)" "unprognostic (8.36e-5)" "unprognostic (1.72e-1)" "unprognostic (8.91e-2)" "unprognostic (1.08e-2)" "unprognostic (3.81e-2)" "unprognostic (6.36e-2)" "unprognostic (7.47e-6)" "unprognostic (3.04e-3)" "unprognostic (1.66e-1)" "unprognostic (2.75e-2)" "prognostic unfavorable (3.11e-4)" 1.3 2.2 18.4 0.7 18.6 0.1 1.5 10.3 25.9 2.5 2.4 1.6 0.1 3.3 0.7 0.6 1.5 0.7 33.7 20.3 12.6 0.6 0.3 1.2 0.3 14.8 15.0 5.3 0.9 0.0 10.4 0.2 15.1 4.9 0.0 15.9 2.6 2.0 2.0 1.2 0.9 1.1 12.1 1.2 1.3 7.9 16.4 0.0 1.0 0.2 0.2 1.0 1.3 18.1 0.1 15.2 53.2 70.0 0.1 0.4 0.0 4.6 0.6 2.9 0.6 0.0 0.4 0.0 1.8 2.4 5.1 0.0 10.4 10.3 0.3 0.0 2.0 0.0 0.1 5.7 9.3 0.0 10.6 4.7 4.9 1.7 0.2 0.9 5.4 0.0 0.0 0.5 7.7 4.5 0.0 0.0 9.1 0.9 5.1 0.0 0.0 8.7 0.0 1.1 8.3 72.0 1.7 0.1 9.7 3.1 0.2 0.1 9.0 13.1 21.7 0.0 12.8 0.1 3.9 0.0 22.0 0.0 1.4 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.5 0.1 0.0 0.3 0.1 0.0 0.0 0.1 18.4 18.6 10.3 25.9 20.3 12.6 14.8 15.0 15.1 12.1 16.4 18.1 0.3 0.0 0.0 7.2 0.1 0.5 0.5 0.1 0.6 64.9 0.4 0.6 20.1 0.0 0.1 0.0 58.4 0.0 0.1 0.0 0.0 0.3 5.3 0.1 5.0 1.2 1.8 0.0 12.2 0.0 0.1 2.7 2.0 0.3 0.0 0.7 0.0 0.0 0.2 33.7 13.6 0.0 0.0 0.0 0.8 9.0 4.1 0.1 1.8 0.0 0.1 7.5 0.0 12.1 18.4 0.5 0.0 4.5 0.0 0.7 0.0 0.0 0.0 13.8 0.0 1.0 5.7 7.0 5.2 0.3 0.1 0.0 0.5 4.5 0.0 0.2 DRAM2 "MGC54289, PRO180, RP5-1180E21.1, TMEM77, WWFQ154" ENSG00000156171 "DNA damage regulated autophagy modulator 2" Q6UX65 1 111117163-111140203 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018036, HPA061701" Supported Enhanced "Golgi apparatus,Vesicles" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus, Vesicles" "HPA018036: AB_1858134, HPA061701: AB_2684590" "unprognostic (9.38e-3)" "unprognostic (1.58e-2)" "unprognostic (2.16e-3)" "unprognostic (5.22e-2)" "unprognostic (1.12e-2)" "unprognostic (2.65e-2)" "prognostic unfavorable (3.45e-5)" "unprognostic (6.57e-3)" "prognostic unfavorable (6.43e-4)" "unprognostic (2.69e-1)" "unprognostic (4.37e-3)" "unprognostic (2.66e-1)" "prognostic unfavorable (7.45e-4)" "unprognostic (1.10e-1)" "unprognostic (1.63e-1)" "unprognostic (2.29e-1)" "unprognostic (1.77e-3)" 38.0 23.1 13.9 33.1 14.5 17.9 26.8 17.7 19.9 23.1 22.7 26.7 28.6 17.7 17.6 15.0 30.1 36.4 23.7 13.5 15.2 26.5 24.9 25.0 55.3 15.6 14.9 24.3 25.6 28.3 4.6 41.2 16.2 17.8 30.7 16.9 25.8 16.7 16.6 17.9 26.3 17.0 15.5 45.3 23.4 10.3 15.0 27.8 22.0 23.6 50.3 29.4 4.2 17.8 38.0 12.9 24.0 10.8 57.3 56.2 23.4 28.7 29.9 24.7 24.9 12.5 38.2 28.7 17.2 25.6 12.1 37.4 30.5 24.0 31.9 26.8 25.6 16.8 18.4 16.4 41.4 19.4 15.4 38.5 41.4 18.3 38.4 53.6 29.9 29.1 34.1 19.6 30.1 19.6 16.6 28.8 14.5 43.3 13.2 11.1 40.0 14.0 42.5 25.8 19.1 18.2 16.8 52.4 80.1 33.1 16.7 84.6 24.8 20.6 13.8 16.2 18.9 25.7 9.6 29.8 33.4 34.7 29.6 41.7 47.3 11.5 14.2 61.0 19.4 65.7 17.5 15.3 45.1 54.1 22.3 19.0 7.2 25.0 49.8 28.6 17.7 35.5 13.9 14.5 17.7 19.9 13.5 15.2 15.6 14.9 16.2 15.5 15.0 17.8 34.5 12.8 12.0 17.3 146.2 47.0 54.4 82.5 34.1 11.6 53.6 43.9 29.7 32.9 53.1 44.1 2.1 98.1 38.9 41.2 43.0 59.2 8.5 51.7 19.5 36.4 13.2 28.6 20.6 46.6 102.3 39.2 24.5 17.6 23.6 18.5 42.8 26.0 183.1 20.2 31.7 45.7 77.3 189.4 97.8 7.8 33.5 110.3 81.8 39.4 89.0 27.1 56.7 31.7 42.6 41.9 64.3 24.8 54.7 46.3 88.4 80.4 95.8 10.1 39.5 26.4 32.5 4.7 14.6 40.8 53.0 73.3 38.6 26.3 43.7 70.1 DRG2 ENSG00000108591 "Developmentally regulated GTP binding protein 2" P55039 17 18087892-18107970 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007716 Approved Supported Nucleoplasm,Vesicles,Cytosol No No "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 12: NES - Nervous system development" "Cluster 39: Non-specific - Basic cellular processes" "Vesicles, Cytosol" Nucleoplasm "HPA007716: AB_1078705" "unprognostic (7.47e-2)" "unprognostic (1.29e-1)" "unprognostic (4.78e-2)" "prognostic favorable (1.56e-4)" "unprognostic (1.26e-3)" "unprognostic (7.86e-2)" "unprognostic (8.85e-2)" "unprognostic (5.72e-2)" "unprognostic (8.49e-2)" "unprognostic (1.25e-1)" "unprognostic (2.88e-3)" "prognostic unfavorable (7.34e-4)" "unprognostic (3.10e-1)" "unprognostic (2.18e-1)" "unprognostic (1.49e-1)" "unprognostic (5.64e-2)" "unprognostic (1.10e-1)" 19.3 19.1 14.2 12.8 14.8 15.9 19.6 14.8 15.0 21.6 13.6 19.4 14.8 22.3 12.9 21.6 19.8 12.6 19.8 14.9 15.7 18.5 16.6 15.7 18.4 15.2 15.4 22.5 19.6 15.8 17.8 12.3 16.1 20.1 10.0 5.2 17.0 15.2 36.6 20.3 17.4 13.7 15.4 19.8 17.9 8.9 14.9 16.0 18.4 16.5 14.9 20.0 18.3 16.5 37.1 51.1 17.4 17.3 31.1 31.7 33.1 24.8 24.7 40.0 37.0 55.5 21.8 35.5 31.8 29.4 21.2 38.9 28.5 35.1 27.4 32.1 74.2 16.0 26.5 31.5 33.4 14.3 24.2 36.4 30.5 39.1 33.0 22.9 38.5 46.8 27.6 13.7 23.6 42.5 38.7 25.8 12.9 51.4 36.1 41.5 41.8 66.7 24.3 21.6 9.9 28.0 25.2 15.2 31.9 102.8 30.0 21.4 29.2 19.6 18.3 23.0 42.8 15.5 19.4 20.1 27.9 26.2 36.6 17.7 21.1 23.6 24.6 23.3 20.2 14.9 17.8 20.0 24.6 17.7 16.9 18.7 2.8 28.2 30.5 13.8 24.9 19.3 14.2 14.8 14.8 15.0 14.9 15.7 15.2 15.4 16.1 15.4 14.9 16.5 23.8 0.0 12.4 8.5 19.5 16.7 19.9 21.2 11.4 14.9 18.8 23.0 3.9 24.3 13.2 7.3 2.1 37.5 26.3 20.1 29.4 29.4 7.3 12.8 19.3 20.8 21.6 10.1 11.9 27.1 40.8 19.4 17.9 12.9 12.0 32.6 16.4 19.4 32.2 6.7 10.0 19.7 16.2 21.4 12.2 14.2 21.5 18.0 12.4 8.4 23.9 19.6 23.7 4.0 8.0 24.8 16.2 24.5 22.9 17.4 31.4 31.8 9.3 13.4 6.6 22.0 21.7 12.1 13.0 18.2 11.6 39.3 21.9 33.9 24.5 14.4 DTD2 "C14orf126, MGC9912" ENSG00000129480 "D-aminoacyl-tRNA deacylase 2" Q96FN9 14 31446036-31457506 "Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 35.2;Oligodendrocytes: 40.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001117 Approved Approved Vesicles NA NA "Cluster 15: NK-cells - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA001117: AB_2666204" "unprognostic (2.56e-3)" "unprognostic (9.38e-2)" "unprognostic (1.27e-3)" "unprognostic (3.24e-2)" "unprognostic (8.45e-2)" "prognostic unfavorable (9.33e-4)" "unprognostic (3.04e-2)" "unprognostic (1.64e-1)" "unprognostic (8.74e-3)" "unprognostic (2.91e-1)" "unprognostic (5.28e-2)" "unprognostic (6.96e-2)" "unprognostic (1.24e-1)" "unprognostic (2.32e-1)" "unprognostic (3.06e-2)" "unprognostic (1.22e-2)" "prognostic unfavorable (5.74e-6)" 8.6 6.3 4.7 4.9 6.8 2.3 7.1 5.2 6.5 4.0 5.2 4.8 3.9 5.2 5.0 5.7 4.9 3.5 3.1 5.3 5.3 5.8 8.1 5.8 5.5 5.5 5.9 5.3 6.3 6.1 4.4 4.3 5.9 5.7 5.4 5.0 6.0 3.9 1.6 5.6 3.7 5.5 4.9 4.9 4.0 4.0 6.2 5.0 6.2 1.6 5.5 4.7 3.8 8.1 11.4 9.5 8.1 10.6 14.6 12.3 5.5 10.3 10.0 8.0 7.1 5.2 10.7 21.6 6.8 11.8 8.6 10.8 13.0 11.6 13.6 11.7 5.7 6.2 6.5 29.0 15.7 12.6 7.3 14.0 12.9 7.1 15.9 6.7 11.8 12.8 12.3 9.9 10.7 13.7 18.3 11.3 11.0 19.6 9.7 12.3 6.0 11.3 15.0 9.8 12.1 8.0 16.8 21.6 12.4 6.9 19.8 6.5 8.6 8.7 7.7 7.1 9.1 12.3 24.5 20.7 3.8 11.4 14.3 2.5 2.6 1.0 2.0 2.2 2.9 2.7 3.0 2.2 3.7 3.2 4.5 3.0 1.5 3.7 1.2 2.2 1.6 2.8 4.7 6.8 5.2 6.5 5.3 5.3 5.5 5.9 5.9 4.9 6.2 8.1 2.9 9.6 9.0 10.1 7.6 5.2 5.7 5.1 13.1 5.9 6.1 4.3 4.8 15.7 4.9 3.7 8.4 9.1 4.9 3.3 3.9 5.7 4.4 6.8 7.2 3.8 3.0 8.0 9.2 6.2 6.3 6.2 5.1 3.0 1.3 5.9 3.9 11.6 5.1 5.0 12.7 6.7 14.2 5.5 3.7 6.6 7.5 4.0 3.6 2.8 4.8 9.5 7.2 35.2 40.2 5.2 3.9 8.2 7.1 6.0 3.3 9.7 6.2 9.2 0.0 7.4 6.8 10.1 2.7 16.2 5.4 2.7 5.4 10.3 7.2 4.2 DTWD1 "MDS009, MGC111207" ENSG00000104047 "DTW domain containing 1" Q8N5C7 15 49621037-49656232 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042214 Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome,Vesicles" Yes No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome, Vesicles" "HPA042214: AB_2677903" "unprognostic (2.60e-2)" "unprognostic (1.73e-1)" "unprognostic (3.00e-1)" "unprognostic (3.70e-4)" "unprognostic (8.12e-2)" "unprognostic (2.37e-1)" "unprognostic (1.82e-1)" "unprognostic (9.87e-2)" "unprognostic (4.44e-3)" "unprognostic (4.25e-2)" "unprognostic (5.42e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-3)" "unprognostic (1.02e-1)" "unprognostic (7.85e-2)" "unprognostic (2.80e-2)" "unprognostic (2.35e-1)" 19.6 11.8 7.7 13.0 10.1 5.4 18.2 8.2 9.1 27.4 6.5 21.1 7.4 22.6 16.8 13.3 21.1 23.0 11.0 9.0 8.9 11.0 11.5 10.9 12.9 5.7 6.9 22.7 33.3 11.5 9.2 12.8 6.0 15.7 11.9 8.8 21.5 14.7 10.3 12.2 9.1 20.5 6.4 9.0 14.9 9.5 9.9 11.7 17.6 21.1 10.0 20.4 15.9 9.8 10.0 11.9 21.2 11.5 41.3 84.1 16.6 29.3 28.6 36.8 27.5 4.2 8.3 16.7 20.3 38.7 16.8 17.8 15.6 15.8 37.7 10.8 11.2 13.8 23.5 14.5 29.1 18.0 11.1 38.8 20.4 24.3 29.7 32.9 15.5 19.3 26.3 17.3 41.7 23.3 12.3 15.1 12.4 22.6 15.7 17.4 44.7 64.9 12.3 7.1 18.6 14.4 34.7 11.5 27.3 22.1 12.1 25.4 10.7 43.6 17.3 25.6 32.3 13.2 22.2 10.0 37.5 53.9 28.3 8.7 9.7 5.2 6.8 11.7 9.8 9.7 10.3 11.6 12.8 10.1 12.0 11.5 2.6 13.9 15.3 25.3 8.9 6.0 7.7 10.1 8.2 9.1 9.0 8.9 5.7 6.9 6.0 6.4 9.9 9.8 39.9 19.2 15.0 36.6 16.6 19.2 15.4 31.9 18.2 41.8 23.0 34.0 18.8 12.8 22.1 35.0 31.3 23.4 27.1 4.7 31.3 20.1 21.0 27.8 88.1 23.6 15.5 20.8 57.2 21.0 27.7 49.9 20.4 14.1 7.0 29.3 25.4 14.9 19.5 18.5 55.2 19.2 40.7 16.4 14.9 11.2 37.9 16.7 16.0 18.7 10.4 20.3 18.6 33.7 66.1 20.8 10.3 28.2 27.0 21.5 9.5 22.0 37.9 40.0 6.6 35.5 46.7 51.2 44.3 19.6 19.0 9.7 16.2 35.4 17.1 12.7 DTX4 "KIAA0937, RNF155" ENSG00000110042 "Deltex E3 ubiquitin ligase 4" Q9Y2E6 11 59171430-59208588 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 33.6;Oligodendrocytes: 33.9" "Cancer enhanced" "Detected in all" "thyroid cancer: 63.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 62.8;CACO-2: 34.5;CAPAN-2: 37.7;OE19: 35.4;RT4: 95.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056760, HPA059294" Approved Approved Vesicles NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA056760: AB_2683228, HPA059294: AB_2683969" "unprognostic (3.23e-2)" "unprognostic (1.57e-1)" "unprognostic (1.10e-2)" "unprognostic (4.98e-2)" "unprognostic (4.97e-2)" "unprognostic (5.03e-1)" "unprognostic (2.92e-1)" "unprognostic (1.06e-1)" "unprognostic (3.75e-1)" "unprognostic (1.14e-1)" "unprognostic (5.69e-2)" "unprognostic (3.04e-1)" "prognostic unfavorable (8.94e-4)" "unprognostic (5.51e-2)" "unprognostic (2.51e-1)" "prognostic favorable (5.81e-4)" "unprognostic (2.57e-3)" 10.4 1.9 13.9 5.5 21.2 9.3 9.5 21.4 20.0 8.0 8.2 17.5 16.4 3.8 1.9 4.7 5.8 4.9 3.2 13.2 21.2 8.5 32.5 18.1 5.3 30.2 22.4 15.0 7.9 1.0 4.1 14.8 27.0 7.5 17.2 10.4 21.7 3.1 1.4 3.9 14.4 2.5 33.5 6.7 11.6 1.7 25.6 1.5 10.2 1.7 6.5 15.0 3.9 50.5 4.8 5.7 30.5 0.6 8.5 0.5 62.8 0.4 2.7 0.3 0.4 34.5 37.7 11.6 2.1 0.7 1.2 16.5 9.5 11.8 0.1 0.8 0.5 0.1 6.6 11.2 2.4 0.9 2.3 1.4 19.3 0.1 0.5 2.1 0.0 2.1 0.1 1.1 1.4 2.7 0.5 0.1 16.1 35.4 1.5 4.1 27.1 1.3 2.6 95.2 0.0 0.1 24.3 6.4 0.8 7.7 4.9 0.5 0.3 0.1 4.9 0.1 0.0 0.4 0.1 1.1 0.2 2.8 2.6 0.7 0.4 0.4 0.0 0.4 0.0 1.0 0.0 0.0 0.6 1.3 0.0 0.0 1.5 0.0 0.2 2.8 0.0 0.1 13.9 21.2 21.4 20.0 13.2 21.2 30.2 22.4 27.0 33.5 25.6 50.5 8.9 19.2 16.8 9.4 3.1 1.7 3.2 7.9 2.2 2.0 2.9 3.9 1.4 28.6 21.8 7.3 0.0 15.0 6.9 33.6 0.0 10.2 0.4 1.5 8.1 3.6 4.9 0.0 12.0 4.9 19.2 7.2 12.2 3.0 1.3 4.9 5.7 23.1 3.7 0.0 8.4 10.5 2.0 2.5 2.5 0.4 4.1 2.7 5.4 3.7 0.9 30.3 0.0 7.5 33.9 10.8 16.3 3.4 0.0 3.1 19.8 9.1 14.9 2.0 0.0 22.1 3.6 0.4 1.7 1.8 1.3 5.5 1.2 5.9 18.5 22.5 DUSP22 "JKAP, JSP1, MKPX, VHX" ENSG00000112679 "Dual specificity phosphatase 22" Q9NRW4 6 291630-351355 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 270.6;U-266/70: 130.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031394 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 25: RPMI-8226 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Vesicles" "HPA031394: AB_10604114" "unprognostic (7.34e-3)" "unprognostic (7.94e-3)" "unprognostic (1.37e-2)" "unprognostic (1.14e-1)" "unprognostic (3.46e-1)" "unprognostic (1.70e-2)" "unprognostic (9.08e-3)" "unprognostic (2.48e-1)" "unprognostic (9.06e-2)" "unprognostic (5.56e-3)" "unprognostic (3.10e-2)" "unprognostic (3.04e-1)" "unprognostic (1.77e-1)" "unprognostic (3.97e-2)" "unprognostic (3.07e-1)" "unprognostic (2.35e-1)" "unprognostic (1.09e-1)" 36.9 16.4 25.6 27.7 29.1 23.7 33.0 27.4 28.8 31.6 21.2 47.8 22.5 28.9 12.2 45.7 25.9 21.3 42.1 25.1 27.1 32.4 32.7 38.5 32.4 32.3 28.5 19.6 40.8 13.2 21.2 27.3 30.3 23.2 16.1 7.8 30.4 15.1 52.3 41.4 33.7 22.0 28.0 43.9 32.7 44.9 29.3 15.0 28.1 37.7 30.5 30.3 36.8 42.7 13.7 8.3 17.3 25.9 19.5 21.5 22.8 9.9 8.0 8.6 10.3 8.8 15.1 28.4 23.3 10.3 18.3 9.4 21.9 18.3 6.1 68.6 25.1 19.3 7.1 24.7 9.9 7.0 24.4 16.2 54.1 6.2 11.3 14.1 24.8 24.0 18.3 92.2 7.2 8.2 10.3 25.1 10.4 10.0 18.7 20.2 11.7 270.6 16.2 5.8 29.7 11.6 8.5 3.4 29.6 37.4 17.6 8.9 34.2 7.7 10.1 7.8 6.0 130.0 98.6 40.0 3.0 19.0 17.7 36.4 32.5 13.6 8.6 26.5 6.2 40.4 6.7 9.1 33.5 33.3 6.1 8.8 21.8 5.9 25.1 28.8 15.9 19.6 25.6 29.1 27.4 28.8 25.1 27.1 32.3 28.5 30.3 28.0 29.3 42.7 45.5 16.0 21.3 5.5 53.7 26.5 22.0 33.3 14.2 5.7 19.4 17.5 40.8 10.0 30.7 5.5 0.0 10.8 51.1 11.7 21.5 24.2 13.4 18.6 8.2 33.4 9.5 8.2 8.5 51.4 7.7 21.9 15.3 12.9 33.0 8.8 21.8 25.0 30.1 0.0 6.1 14.7 32.6 38.6 43.0 20.5 15.5 47.1 46.2 21.5 78.4 14.9 36.0 7.1 25.9 29.2 12.4 9.4 59.7 16.5 23.2 18.2 39.7 3.2 26.3 11.6 22.8 34.5 73.8 42.5 37.1 6.6 21.3 6.8 15.4 27.9 DYRK4 ENSG00000010219 "Dual specificity tyrosine phosphorylation regulated kinase 4" Q9NR20 12 4562204-4615302 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 36.7" "Group enriched" "Detected in all" 5 "Early spermatids: 392.2;Late spermatids: 393.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA028065, HPA056073" Enhanced Enhanced Vesicles No No "Cluster 14: Monocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA028065: AB_10601212, HPA056073: AB_2683028" "unprognostic (2.50e-1)" "unprognostic (1.55e-1)" "unprognostic (1.22e-1)" "unprognostic (3.56e-3)" "unprognostic (2.62e-1)" "unprognostic (4.07e-3)" "unprognostic (2.03e-2)" "unprognostic (4.69e-2)" "unprognostic (1.29e-1)" "unprognostic (7.13e-2)" "unprognostic (1.22e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (6.52e-6)" "unprognostic (1.86e-1)" "unprognostic (9.71e-2)" "unprognostic (1.04e-1)" "unprognostic (3.98e-2)" 2.1 4.2 3.9 3.4 4.2 4.6 6.4 5.1 7.6 5.9 4.2 5.4 4.6 5.0 17.0 4.0 5.0 4.4 4.7 4.2 4.4 3.5 4.2 4.7 5.9 4.4 4.5 5.1 3.0 5.0 3.6 6.8 4.8 5.0 6.2 7.7 3.7 7.2 2.2 4.9 4.0 5.1 4.1 6.2 3.2 36.7 4.8 4.3 9.1 4.1 5.4 4.7 2.0 5.7 2.0 3.2 3.9 4.3 5.8 7.1 4.7 2.4 4.8 5.4 5.9 0.6 3.2 6.1 0.3 6.9 3.7 4.2 3.0 4.5 4.2 4.7 6.8 4.2 1.0 3.6 16.4 3.7 3.3 4.9 9.6 3.8 12.4 10.1 7.8 6.5 1.8 6.7 4.9 4.3 3.5 9.1 5.3 1.0 1.8 0.7 2.8 2.6 6.7 1.9 0.0 1.5 0.5 2.4 3.3 8.4 1.9 3.3 0.5 6.3 4.9 0.6 3.1 1.9 2.6 3.8 3.3 5.8 3.3 0.3 1.7 0.8 0.5 1.3 0.6 4.4 0.8 0.9 1.6 3.0 0.8 0.9 0.0 0.7 3.5 0.8 0.7 0.8 3.9 4.2 5.1 7.6 4.2 4.4 4.4 4.5 4.8 4.1 4.8 5.7 13.0 12.8 16.2 11.1 15.8 8.9 13.2 31.2 14.8 20.7 21.2 30.4 23.8 7.2 19.9 16.5 10.4 15.7 16.7 5.2 31.3 25.1 392.2 14.0 22.5 15.5 5.4 12.2 10.3 27.1 12.0 17.3 14.3 13.3 17.7 19.0 8.2 9.8 49.7 13.5 10.4 75.4 14.2 16.1 9.3 393.1 15.2 18.7 16.0 9.4 14.5 19.4 13.4 14.1 16.1 20.1 14.2 31.6 22.9 16.4 7.3 35.6 13.9 21.7 6.6 15.2 17.6 23.7 39.0 20.4 7.5 9.9 12.7 40.6 17.3 11.8 DZIP3 "hRUL138, PPP1R66" ENSG00000198919 "DAZ interacting zinc finger protein 3" Q86Y13 3 108589705-108694840 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 327.4;Respiratory ciliated cells: 218.2;Spermatocytes: 351.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035066, HPA049232" Approved Approved Vesicles No No "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA035066: AB_10601549, HPA049232: AB_2680684" "unprognostic (1.14e-1)" "unprognostic (1.90e-1)" "unprognostic (7.68e-2)" "unprognostic (3.12e-2)" "unprognostic (2.15e-1)" "unprognostic (2.37e-2)" "unprognostic (3.33e-1)" "unprognostic (5.16e-2)" "unprognostic (2.74e-1)" "unprognostic (3.76e-2)" "unprognostic (2.59e-3)" "unprognostic (5.38e-2)" "prognostic favorable (3.65e-4)" "unprognostic (6.06e-2)" "unprognostic (2.78e-2)" "unprognostic (5.51e-3)" "unprognostic (3.81e-2)" 5.2 9.7 15.6 4.9 19.4 4.0 5.3 11.8 18.6 5.3 22.6 5.1 3.0 7.9 10.1 3.9 18.7 5.9 11.7 18.8 18.5 10.9 4.3 6.5 10.2 13.3 14.9 10.5 5.3 7.8 24.5 4.9 12.4 9.7 4.7 29.8 3.6 7.0 12.4 3.7 3.9 5.2 10.4 8.3 6.6 34.6 15.5 8.5 12.8 16.2 8.0 5.2 3.4 15.0 9.8 8.2 24.8 14.7 10.7 10.8 8.6 6.1 12.2 10.1 13.9 12.1 6.8 18.0 12.8 6.6 20.9 3.5 13.7 5.3 21.0 6.6 6.1 8.1 3.4 8.5 6.3 3.3 4.5 11.8 2.8 9.4 11.4 10.2 6.4 10.9 8.0 8.7 19.6 8.6 8.2 3.5 15.5 5.0 6.2 10.4 20.5 1.8 8.4 4.7 17.0 16.2 9.8 1.0 11.1 21.6 15.1 2.8 7.6 9.0 13.7 1.8 5.3 9.6 6.0 34.7 6.8 2.7 11.3 6.5 0.5 1.2 4.1 0.8 5.0 6.3 4.2 5.1 0.5 4.6 3.6 4.8 0.1 10.6 1.5 1.5 6.0 1.5 15.6 19.4 11.8 18.6 18.8 18.5 13.3 14.9 12.4 10.4 15.5 15.0 7.3 12.8 12.8 86.8 14.8 7.5 8.6 16.3 9.1 67.8 9.6 8.3 45.0 4.3 26.6 33.1 327.4 21.9 17.1 4.1 13.7 12.9 28.4 106.1 16.0 8.7 52.8 11.1 145.2 9.0 8.8 18.2 9.2 9.2 8.8 30.9 7.5 4.4 9.4 77.4 103.4 6.9 34.6 5.7 7.5 59.9 17.4 5.7 7.2 37.5 10.5 32.9 11.3 79.4 80.6 8.9 4.6 17.7 9.0 6.9 4.5 20.6 218.2 33.7 19.7 16.6 17.7 351.3 112.5 4.4 7.4 14.8 29.4 35.4 7.4 5.6 E2F5 ENSG00000133740 "E2F transcription factor 5" Q15329 8 85177154-85217158 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cilium biogenesis/degradation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 29.6" "Cell type enhanced" "Detected in many" "B-cells: 23.7;Plasma cells: 29.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory B-cell: 13.4;naive B-cell: 8.9" "Lineage enriched" "Detected in many" 9 "B-cells: 13.4" "Cell line enhanced" "Detected in many" "AF22: 82.6;Daudi: 158.0;U-698: 77.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055723, HPA065441" Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "Nucleoli, Vesicles" "HPA055723: AB_2682897, HPA065441: " "unprognostic (8.73e-2)" "unprognostic (3.45e-1)" "unprognostic (3.15e-2)" "unprognostic (1.02e-3)" "unprognostic (6.73e-3)" "unprognostic (1.62e-1)" "unprognostic (3.36e-5)" "unprognostic (1.23e-1)" "unprognostic (9.53e-2)" "unprognostic (1.28e-1)" "unprognostic (3.18e-1)" "unprognostic (3.87e-2)" "prognostic unfavorable (1.89e-6)" "unprognostic (2.88e-2)" "unprognostic (3.25e-2)" "unprognostic (3.64e-1)" "unprognostic (2.95e-3)" 1.8 3.9 4.8 8.0 5.2 1.7 6.7 4.6 6.5 5.2 5.1 6.6 4.9 4.5 8.1 2.2 8.0 4.3 1.9 5.1 5.8 8.1 3.0 4.1 25.9 5.5 5.2 4.9 4.3 13.2 3.7 5.0 5.0 3.6 7.8 0.9 2.3 3.3 0.4 0.8 3.8 4.1 5.1 6.9 5.5 8.5 5.3 10.7 8.7 0.9 29.6 6.9 0.9 5.5 14.2 15.9 82.6 29.7 1.5 2.2 25.0 2.7 6.9 2.4 7.4 9.6 17.4 158.0 10.3 3.5 28.4 2.6 51.0 4.3 3.0 16.0 20.1 16.4 8.3 22.4 13.4 4.8 0.1 3.3 6.9 3.5 12.0 15.7 2.7 16.5 34.7 1.2 4.6 10.0 15.8 10.8 26.1 28.0 12.9 12.9 3.4 17.9 27.5 10.7 9.8 29.8 1.8 5.8 23.8 32.6 33.5 5.2 0.1 3.7 2.5 4.6 10.5 27.6 20.6 77.1 4.3 4.1 8.0 0.0 0.0 0.0 0.1 0.0 0.0 13.4 0.0 0.0 0.1 8.9 0.2 0.4 0.0 1.4 0.0 1.5 0.6 0.6 4.8 5.2 4.6 6.5 5.1 5.8 5.5 5.2 5.0 5.1 5.3 5.5 1.1 0.0 6.5 3.6 23.7 2.3 3.3 1.3 1.2 0.9 5.6 6.0 1.0 5.7 2.9 5.5 10.4 4.1 5.1 3.3 0.0 3.3 7.6 7.3 5.2 1.5 7.8 1.3 7.7 2.6 1.1 3.0 4.1 7.5 1.3 5.5 0.4 2.4 0.5 0.0 4.6 2.7 2.0 0.8 1.0 3.8 1.5 1.9 3.6 4.7 0.3 5.2 4.1 11.6 4.2 3.0 1.7 1.9 29.6 6.9 0.8 5.8 8.6 1.6 0.0 5.0 4.5 8.1 4.6 2.3 2.8 1.1 2.5 4.6 3.7 2.1 EAF1 ENSG00000144597 "ELL associated factor 1" Q96JC9 3 15427598-15450635 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 57.1" "Group enriched" "Detected in all" 6 "Early spermatids: 268.7;Late spermatids: 389.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 137.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059516, HPA060569, HPA069538" Supported Approved "Nucleoplasm,Nuclear bodies,Vesicles" NA No "Cluster 16: MAIT-cells - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Nuclear bodies" Vesicles "HPA059516: AB_2684048, HPA060569: AB_2684322, HPA069538: AB_2686147" "unprognostic (1.26e-1)" "unprognostic (1.61e-2)" "unprognostic (6.37e-2)" "unprognostic (1.13e-1)" "unprognostic (2.68e-1)" "unprognostic (5.47e-2)" "unprognostic (3.14e-3)" "prognostic unfavorable (6.87e-4)" "unprognostic (3.22e-1)" "unprognostic (3.16e-2)" "unprognostic (3.22e-1)" "unprognostic (8.45e-2)" "unprognostic (2.06e-2)" "unprognostic (5.17e-2)" "unprognostic (1.09e-1)" "unprognostic (1.46e-2)" "unprognostic (1.64e-1)" 12.9 9.0 9.2 10.5 8.9 57.1 9.1 7.2 9.4 7.2 7.7 9.0 10.6 7.9 7.6 9.8 7.0 10.4 5.1 10.3 11.1 11.2 19.0 8.3 10.7 9.6 10.3 5.6 9.8 11.8 8.6 10.2 12.3 10.0 9.9 7.7 6.9 6.8 5.3 10.7 10.0 8.3 7.8 9.8 11.4 7.3 10.6 10.6 10.5 5.8 11.1 11.5 5.8 7.9 10.3 16.6 17.1 17.6 9.8 8.3 137.4 14.7 10.5 16.7 16.3 22.7 11.4 28.7 9.3 10.9 10.9 8.6 22.5 13.2 19.2 23.6 16.2 24.8 14.5 20.8 22.1 23.6 19.2 11.0 22.8 24.3 16.2 12.8 16.8 23.1 26.9 20.6 14.1 21.2 23.6 13.2 30.7 19.3 16.9 21.3 14.2 16.0 14.5 17.8 17.6 30.6 18.2 16.7 17.6 21.9 25.2 18.5 16.6 17.5 12.8 15.6 21.8 27.1 58.3 29.7 17.0 27.7 21.1 8.0 7.1 4.6 11.1 5.4 14.3 4.9 9.1 8.7 4.2 3.6 5.4 8.7 6.5 8.1 6.9 9.8 10.9 4.4 9.2 8.9 7.2 9.4 10.3 11.1 9.6 10.3 12.3 7.8 10.6 7.9 11.5 9.6 17.3 6.8 14.2 46.9 9.1 6.0 14.2 8.1 15.8 7.7 4.8 15.7 9.0 12.9 6.2 8.0 29.1 15.5 9.8 8.6 268.7 10.8 16.0 11.8 34.3 7.8 16.4 8.2 14.6 13.9 16.3 14.1 10.2 9.9 12.1 30.4 15.8 21.9 14.0 12.5 12.2 30.7 31.6 389.5 11.5 37.6 23.2 3.7 19.4 5.5 22.6 5.5 10.7 15.6 10.3 12.0 12.2 16.1 16.0 29.7 8.6 6.4 26.3 13.6 11.0 21.5 11.6 17.7 54.3 35.8 22.0 4.3 12.8 19.9 EBF1 "COE1, EBF, OLF1" ENSG00000164330 "EBF transcription factor 1" Q9UH73 5 158695916-159099916 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 37.7" "Cell type enhanced" "Detected in many" "Adipocytes: 79.8;Fibroblasts: 108.4;Leydig cells: 285.5;Microglial cells: 255.8;Peritubular cells: 121.5;Sertoli cells: 98.6;Smooth muscle cells: 138.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22 "memory B-cell: 12.1;naive B-cell: 10.2" "Lineage enriched" "Detected in single" 24 "B-cells: 12.1" "Cell line enhanced" "Detected in many" "ASC diff: 30.0;HSkMC: 26.7;REH: 82.6;U-2197: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061169 Approved Nucleoplasm,Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA061169: AB_2684441" "unprognostic (7.86e-2)" "unprognostic (3.08e-2)" "unprognostic (7.29e-2)" "unprognostic (4.70e-2)" "unprognostic (2.63e-1)" "unprognostic (1.39e-2)" "unprognostic (1.78e-1)" "unprognostic (1.60e-1)" "unprognostic (5.75e-2)" "unprognostic (1.60e-1)" "unprognostic (4.58e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (9.62e-7)" "prognostic unfavorable (7.80e-4)" "unprognostic (5.75e-2)" "unprognostic (5.81e-2)" "unprognostic (4.37e-3)" 37.7 2.8 4.6 3.8 5.0 3.3 20.5 16.4 5.0 14.6 3.9 5.1 1.1 10.5 4.1 3.5 12.5 8.1 7.9 3.8 5.0 3.3 0.4 4.3 9.4 9.8 7.5 8.5 1.7 1.6 2.4 10.8 7.1 4.8 3.2 2.0 4.7 4.4 4.7 7.6 5.5 7.7 11.6 4.7 3.5 4.0 5.3 2.5 7.5 7.4 9.2 10.4 10.3 4.9 0.0 0.5 12.8 0.0 30.0 11.9 0.2 0.3 0.0 0.7 1.7 0.0 0.0 11.9 0.0 4.0 2.4 0.1 0.5 0.1 0.2 2.8 0.2 0.0 3.5 0.0 1.0 0.1 0.3 26.7 0.0 11.4 0.4 0.0 0.0 0.3 0.0 0.2 0.9 0.0 0.1 0.2 1.2 0.0 0.0 82.6 0.6 0.2 0.0 0.0 6.8 1.7 0.7 0.3 0.0 0.2 0.0 0.1 0.0 15.3 1.8 17.5 0.3 0.0 0.1 11.1 10.2 1.2 13.0 0.5 0.0 0.1 0.0 0.0 0.0 12.1 0.0 0.0 0.0 10.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 4.6 5.0 16.4 5.0 3.8 5.0 9.8 7.5 7.1 11.6 5.3 4.9 79.8 0.0 0.5 5.2 76.3 12.2 0.3 0.0 1.8 5.9 0.8 1.9 5.0 0.0 0.7 1.8 0.0 0.2 0.2 0.1 0.0 3.9 28.2 1.5 54.2 56.3 0.0 0.4 0.4 0.0 0.3 108.4 1.5 1.4 0.0 0.0 4.6 2.2 0.8 0.0 1.6 0.1 0.0 0.3 16.6 21.7 285.5 1.9 14.2 255.8 9.3 1.9 0.0 3.0 0.9 0.1 0.0 121.5 7.7 0.7 0.0 0.1 0.9 2.3 98.6 4.6 138.8 2.7 1.3 1.6 7.0 0.4 5.0 10.7 0.0 1.7 EBF3 "COE3, DKFZp667B0210" ENSG00000108001 "EBF transcription factor 3" Q9H4W6 10 129835233-129973053 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.9;brain: 16.9" "Group enriched" "Detected in some" 5 "Adipocytes: 29.6;Endothelial cells: 13.1;Fibroblasts: 14.9;Skeletal myocytes: 33.5;Smooth muscle cells: 11.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 16.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 12.5;HAP1: 13.6;LHCN-M2: 25.4;NB-4: 35.7;RH-30: 13.2;SCLC-21H: 28.7;THP-1: 14.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA061169 Approved Nucleoplasm,Vesicles NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA061169: AB_2684441" "unprognostic (2.96e-1)" "unprognostic (3.78e-2)" "unprognostic (8.63e-3)" "unprognostic (2.60e-2)" "unprognostic (7.68e-2)" "unprognostic (4.50e-3)" "unprognostic (8.53e-6)" "unprognostic (2.93e-2)" "unprognostic (3.99e-2)" "unprognostic (1.04e-1)" "unprognostic (6.12e-2)" "unprognostic (2.63e-1)" "unprognostic (4.16e-3)" "unprognostic (1.37e-3)" "unprognostic (1.66e-1)" "unprognostic (9.49e-2)" "unprognostic (4.58e-2)" 23.9 0.6 0.3 1.0 0.1 0.1 13.7 1.4 0.2 4.1 0.4 2.7 0.2 2.3 0.8 1.4 4.8 2.4 9.4 0.1 2.7 0.5 0.5 0.2 6.9 6.5 8.5 1.0 1.3 2.1 0.9 2.5 3.8 2.4 0.5 1.9 3.0 1.1 7.9 3.3 1.0 1.5 16.9 0.2 1.6 1.6 3.2 1.3 7.3 7.7 1.0 3.3 5.5 1.1 0.0 0.0 0.6 0.1 12.5 10.3 0.1 0.8 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.5 0.0 0.0 13.6 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 2.4 0.0 0.0 0.0 0.7 0.0 0.0 25.4 0.0 0.0 35.7 0.0 0.0 0.0 0.3 13.2 0.0 0.0 0.1 28.7 0.4 0.0 0.0 0.0 0.1 0.0 14.3 0.0 0.0 1.3 8.7 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 1.4 0.2 0.1 2.7 6.5 8.5 3.8 16.9 3.2 1.1 29.6 0.0 0.0 0.3 0.0 1.9 0.0 0.0 0.0 1.8 0.3 0.6 3.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 0.1 13.1 0.0 0.0 0.9 0.0 0.0 14.9 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.5 0.4 0.3 0.4 0.0 1.9 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.7 0.0 33.5 11.7 0.0 3.4 0.1 0.9 0.0 0.2 0.1 0.0 0.1 ECHDC1 dJ351K20.2 ENSG00000093144 "Ethylmalonyl-CoA decarboxylase 1" Q9NTX5 6 127288712-127343609 "Enzymes, Plasma proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 230.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035445, HPA035446" Uncertain Approved Vesicles NA NA 56000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA035445: AB_10669860, HPA035446: AB_2732468" "unprognostic (9.57e-2)" "unprognostic (1.63e-2)" "unprognostic (2.46e-3)" "unprognostic (1.34e-1)" "unprognostic (4.09e-1)" "unprognostic (3.68e-2)" "unprognostic (5.03e-3)" "unprognostic (4.89e-3)" "unprognostic (4.97e-2)" "unprognostic (1.76e-1)" "unprognostic (3.99e-1)" "unprognostic (9.97e-2)" "unprognostic (8.21e-3)" "unprognostic (6.83e-2)" "unprognostic (2.86e-1)" "unprognostic (1.39e-1)" "unprognostic (1.40e-2)" 92.9 29.4 21.8 36.8 24.5 16.2 37.3 26.4 28.6 36.4 32.3 58.4 46.8 21.4 23.0 33.5 23.2 27.5 42.6 22.0 27.0 92.5 93.8 56.8 41.3 28.1 24.7 21.1 27.9 26.2 14.1 36.2 28.5 33.8 53.8 30.0 46.3 28.4 39.3 22.7 40.7 33.4 24.4 28.4 37.0 18.2 24.7 41.1 38.7 52.2 42.6 43.4 23.4 32.3 58.3 45.6 64.0 59.3 92.9 87.7 54.1 92.7 112.1 78.0 99.0 79.7 43.1 87.6 77.8 88.6 88.4 46.9 0.1 69.6 98.3 52.4 43.3 116.9 58.4 128.3 82.6 158.0 63.4 99.6 81.9 73.1 61.6 70.6 71.8 63.2 147.6 51.6 105.7 55.1 105.7 73.5 52.9 29.0 55.8 49.0 78.7 72.3 142.8 70.8 73.3 71.2 52.1 1.8 131.3 48.3 1.8 182.6 75.2 47.8 76.9 121.8 104.8 65.7 141.0 116.3 87.2 136.4 114.7 19.0 71.6 24.0 23.4 57.5 24.7 28.6 19.8 22.9 66.6 29.2 23.7 24.2 28.6 15.3 43.1 50.5 22.1 43.9 21.8 24.5 26.4 28.6 22.0 27.0 28.1 24.7 28.5 24.4 24.7 32.3 37.0 96.1 114.0 32.3 59.7 26.1 42.3 94.2 35.3 26.4 30.8 28.3 60.8 32.9 102.4 31.3 31.3 106.8 49.3 35.6 127.2 76.1 64.7 47.0 48.3 32.6 13.8 22.9 47.4 79.5 85.6 45.8 38.2 40.2 43.7 32.9 26.0 68.8 85.8 28.6 41.0 35.7 59.0 48.4 38.7 24.4 32.9 55.9 35.6 40.3 55.3 33.5 47.4 55.3 95.0 54.4 41.1 31.2 48.3 31.1 74.4 230.3 47.0 42.3 26.3 55.7 33.0 27.6 28.6 34.7 22.9 65.5 46.3 88.2 56.9 52.7 ECSCR "ARIA, ECSM2" ENSG00000249751 "Endothelial cell surface expressed chemotaxis and apoptosis regulator" Q19T08 5 139448560-139462743 "Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 12 "Adipocytes: 235.8;Endothelial cells: 214.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 122 "EFO-21: 172.1;HUVEC TERT2: 443.7;TIME: 330.9" HPA063337 Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA063337: AB_2732701" "unprognostic (5.91e-2)" "unprognostic (2.37e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "unprognostic (3.69e-2)" "unprognostic (2.15e-3)" "unprognostic (3.95e-2)" "unprognostic (1.12e-1)" "unprognostic (2.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.78e-2)" "unprognostic (1.91e-1)" "unprognostic (1.83e-3)" "unprognostic (2.41e-3)" "unprognostic (1.36e-1)" "unprognostic (9.90e-2)" "unprognostic (2.91e-1)" 62.7 12.7 5.5 11.2 5.5 0.2 59.8 5.7 8.5 26.8 5.3 19.4 4.6 29.4 7.4 15.9 33.5 12.1 54.6 5.2 5.9 29.9 6.0 60.1 11.6 6.0 5.9 10.4 6.7 4.7 7.1 33.5 6.3 19.6 8.0 0.8 16.1 7.3 15.1 16.6 20.7 24.4 6.1 23.5 15.2 3.3 6.7 3.5 40.9 17.2 7.2 35.5 26.1 5.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.3 0.0 0.0 172.1 0.3 0.1 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 443.7 0.1 0.0 0.0 1.4 0.0 0.0 0.9 2.5 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.4 330.9 0.4 0.4 0.0 1.7 0.0 0.0 0.2 0.0 1.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.5 5.7 8.5 5.2 5.9 6.0 5.9 6.3 6.1 6.7 5.9 235.8 0.0 3.9 0.0 1.0 14.9 0.4 0.0 0.0 0.0 1.9 2.5 0.0 0.0 0.6 0.0 0.0 0.2 1.0 0.0 0.0 0.6 0.0 0.4 0.5 214.9 0.0 0.0 0.1 1.2 0.1 3.1 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 18.3 0.0 0.0 1.7 10.6 5.6 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.5 0.0 0.0 0.7 0.4 0.0 0.0 1.9 0.0 0.0 0.0 13.9 0.3 1.3 0.9 0.0 1.6 EDA "ED1, ED1-A1, ED1-A2, EDA-A1, EDA-A2, EDA1, EDA2, HED, ODT1, XHED, XLHED" ENSG00000158813 "Ectodysplasin A" Q92838 X 69616067-70039472 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Differentiation "Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Microglial cells: 84.3;Oligodendrocyte precursor cells: 30.2;Oligodendrocytes: 45.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.2;MAIT T-cell: 1.3" "Group enriched" "Detected in many" 5 "monocytes: 1.2;T-cells: 1.3" "Cell line enhanced" "Detected in many" "EFO-21: 5.2;Hep G2: 17.9;OE19: 5.1;RPMI-8226: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA037972, HPA037973" Supported "Vesicles,Lipid droplets" "Secreted - unknown location" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 89: Fibroblasts - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 50: Fibroblasts - ECM organization" Vesicles "Lipid droplets" "HPA037972: AB_2675761, HPA037973: AB_2675762" "unprognostic (3.76e-2)" "unprognostic (8.29e-2)" "unprognostic (1.59e-1)" "unprognostic (3.59e-3)" "unprognostic (7.85e-2)" "unprognostic (1.25e-4)" "unprognostic (4.33e-4)" "unprognostic (5.03e-2)" "unprognostic (1.53e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-2)" "unprognostic (2.01e-1)" "prognostic favorable (1.04e-9)" "unprognostic (8.63e-4)" "unprognostic (7.64e-2)" "unprognostic (9.85e-2)" "unprognostic (2.79e-1)" 4.2 8.5 2.4 0.7 3.0 0.1 2.8 2.2 2.6 4.9 5.2 2.6 0.5 3.0 3.2 1.5 3.8 2.0 10.4 2.1 2.4 3.7 2.1 3.2 0.8 3.2 2.8 4.9 4.2 9.7 1.3 1.8 3.0 3.4 1.1 0.3 2.2 2.2 1.7 4.2 1.1 2.1 2.3 1.4 3.8 1.2 3.1 1.2 6.0 2.0 0.6 2.3 3.9 4.6 0.0 0.6 0.3 2.8 0.5 0.0 0.2 0.0 0.1 0.0 0.0 1.3 0.1 0.3 5.2 0.2 0.2 0.5 3.8 1.4 0.0 0.0 4.5 0.0 0.0 17.9 1.0 0.0 1.1 1.8 1.3 0.0 0.9 0.0 0.5 3.5 0.0 4.9 0.0 1.2 0.0 0.0 2.8 5.1 0.3 0.0 1.2 6.0 0.1 0.0 1.5 0.0 0.1 0.3 0.1 2.0 0.3 0.1 0.5 1.7 2.2 2.3 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.3 0.0 0.6 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.8 0.0 0.0 0.1 2.4 3.0 2.2 2.6 2.1 2.4 3.2 2.8 3.0 2.3 3.1 4.6 3.3 3.2 0.5 21.2 0.3 3.8 2.6 2.0 6.8 0.2 0.9 1.5 12.1 0.0 1.1 5.5 0.0 0.2 0.1 1.0 0.0 1.3 21.3 4.6 1.2 2.2 1.8 0.0 17.9 1.3 0.2 6.0 5.6 12.2 0.0 0.5 11.0 1.2 4.1 0.0 9.6 0.6 0.0 4.8 1.2 9.2 4.7 2.8 1.8 84.3 0.1 1.3 0.0 30.2 45.9 1.1 0.1 2.2 0.2 2.3 0.4 3.1 1.3 0.1 6.6 10.7 5.4 1.7 3.5 3.2 4.1 0.0 2.1 0.4 0.9 1.5 EEA1 ZFYVE2 ENSG00000102189 "Early endosome antigen 1" Q15075 12 92770637-92929331 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005861, CAB018782, HPA038158, HPA038159" Supported Supported Vesicles NA NA 20000 "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB005861: AB_2262056, CAB018782: AB_2277714, HPA038158: AB_10966710, HPA038159: AB_10962356" "unprognostic (5.38e-2)" "unprognostic (4.60e-1)" "unprognostic (2.00e-2)" "unprognostic (5.62e-2)" "unprognostic (1.62e-1)" "unprognostic (1.81e-2)" "unprognostic (6.75e-2)" "unprognostic (6.87e-2)" "unprognostic (1.31e-1)" "unprognostic (5.00e-2)" "unprognostic (2.81e-2)" "unprognostic (1.07e-1)" "unprognostic (2.68e-3)" "unprognostic (5.86e-2)" "unprognostic (2.85e-1)" "unprognostic (3.89e-2)" "unprognostic (1.65e-1)" 11.4 6.6 2.8 6.7 3.0 3.7 7.2 6.6 4.3 9.3 0.0 8.2 6.7 8.7 4.1 13.1 4.8 7.3 7.8 2.7 3.8 6.6 9.5 7.1 5.6 5.3 4.3 8.9 6.0 8.1 2.8 9.4 5.5 7.3 7.0 13.7 7.0 5.7 9.6 10.2 6.6 8.4 3.2 7.3 7.0 5.3 3.5 4.1 8.1 10.4 5.5 8.5 6.8 4.4 14.9 4.9 7.2 5.1 30.1 30.1 16.4 28.8 16.6 15.0 10.6 17.1 4.0 15.2 5.1 20.3 21.3 17.5 16.0 8.1 23.0 10.2 7.8 16.2 5.9 15.7 16.7 11.6 7.3 19.7 11.7 16.1 24.0 16.7 25.3 4.2 12.2 5.0 15.7 6.9 8.4 7.9 7.2 6.0 10.5 9.2 18.2 10.1 7.7 20.4 6.0 4.4 21.2 13.7 12.9 9.9 18.2 10.1 34.4 21.0 8.0 16.8 11.2 5.4 10.1 10.2 7.8 10.1 11.6 0.0 0.6 0.2 0.4 0.4 0.4 0.5 0.4 0.4 0.5 0.4 0.8 0.5 0.5 0.2 0.9 0.5 0.1 0.2 2.8 3.0 6.6 4.3 2.7 3.8 5.3 4.3 5.5 3.2 3.5 4.4 58.3 99.3 59.8 60.7 36.4 37.9 57.6 25.2 35.9 53.1 26.5 24.9 93.0 17.2 32.8 25.8 37.5 65.5 39.4 35.7 43.0 59.0 15.1 37.1 85.7 58.9 16.8 14.9 58.5 34.7 45.8 81.1 29.0 53.6 32.9 29.8 31.4 37.4 36.4 183.4 76.2 26.6 14.2 38.6 36.8 9.5 61.8 44.5 48.0 68.4 44.0 60.0 28.8 94.5 102.5 40.4 35.9 68.1 19.8 50.0 26.3 35.3 26.4 68.4 46.0 104.4 71.0 131.1 30.0 91.3 50.3 113.6 29.8 35.5 30.7 78.1 EEF1AKMT2 "C10orf138, Efm4, METTL10" ENSG00000203791 "EEF1A lysine methyltransferase 2" Q5JPI9 10 124748149-124791887 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 29.1;Distal tubular cells: 66.5;Extravillous trophoblasts: 29.8;Proximal tubular cells: 30.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA050138 Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nuclear bodies, Vesicles, Cytosol" "HPA050138: AB_2681030" "unprognostic (1.64e-3)" "unprognostic (3.42e-2)" "unprognostic (1.34e-1)" "unprognostic (9.75e-2)" "unprognostic (7.19e-2)" "unprognostic (1.17e-1)" "unprognostic (2.33e-2)" "unprognostic (2.29e-3)" "unprognostic (9.04e-3)" "unprognostic (9.76e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (4.82e-4)" "unprognostic (3.90e-2)" "unprognostic (4.44e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (2.53e-4)" "unprognostic (9.09e-2)" 4.8 3.8 3.0 2.1 3.3 3.6 5.3 4.8 4.2 4.6 3.0 3.7 1.8 4.0 4.6 4.0 3.8 2.1 4.1 3.1 3.0 4.9 5.2 3.3 2.5 2.8 3.1 5.5 4.4 4.5 4.3 2.7 2.8 4.3 3.8 2.5 5.1 2.8 4.0 5.0 3.5 2.6 2.7 3.5 3.7 5.6 2.8 3.3 5.1 3.3 3.1 3.4 4.2 3.6 12.6 3.3 4.8 8.0 3.1 8.0 3.1 5.8 7.6 7.4 6.5 4.3 7.1 8.4 3.0 4.7 2.5 3.8 6.8 4.2 11.5 7.0 2.5 6.8 4.2 3.9 6.0 10.9 4.1 3.9 3.9 4.1 9.9 6.2 4.7 7.0 7.6 9.3 9.3 3.7 5.2 8.5 5.9 4.6 4.8 2.3 5.7 2.6 4.6 2.7 1.5 3.8 3.7 6.2 8.7 3.3 5.4 8.5 5.8 2.7 2.9 4.5 8.8 4.3 3.7 6.8 4.9 5.7 3.9 0.8 1.0 1.6 1.6 1.1 2.5 1.9 1.6 2.0 1.2 1.3 2.2 1.6 0.1 4.4 0.8 1.5 1.9 1.1 3.0 3.3 4.8 4.2 3.1 3.0 2.8 3.1 2.8 2.7 2.8 3.6 23.2 3.2 11.3 0.0 8.9 0.0 0.0 0.0 0.0 0.0 20.5 22.4 0.0 0.0 2.5 11.0 0.0 29.1 13.4 0.0 66.5 20.0 0.0 11.4 11.8 7.5 0.0 0.0 0.0 20.4 29.8 10.4 0.0 10.5 2.5 17.8 0.0 0.0 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 11.4 0.0 0.0 0.0 0.0 19.8 0.0 0.0 2.8 0.0 0.0 30.5 3.6 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.0 17.1 7.1 14.7 0.0 0.0 EEF2KMT "EFM3, FAM86A, MGC19636, SB153" ENSG00000118894 "Eukaryotic elongation factor 2 lysine methyltransferase" Q96G04 16 5084284-5097795 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Early spermatids: 189.0;Late spermatids: 393.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 104.8" "Low region specificity" "Detected in all" HPA041610 Approved Uncertain Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 71: Testis - DNA repair" "Cluster 25: RPMI-8226 - Immune response" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA041610: AB_2677581" "unprognostic (4.50e-2)" "unprognostic (1.53e-1)" "unprognostic (8.89e-3)" "unprognostic (3.95e-2)" "unprognostic (2.01e-2)" "unprognostic (7.70e-2)" "prognostic unfavorable (8.85e-4)" "unprognostic (3.53e-1)" "unprognostic (1.37e-1)" "unprognostic (4.03e-2)" "unprognostic (9.73e-2)" "unprognostic (1.53e-1)" "unprognostic (5.24e-3)" "unprognostic (1.82e-1)" "unprognostic (2.07e-1)" "unprognostic (2.75e-2)" "prognostic unfavorable (2.35e-4)" 4.6 5.9 3.2 4.0 3.2 1.1 4.9 2.9 3.4 5.0 3.3 5.0 5.1 6.6 2.7 6.0 4.9 2.8 5.7 2.7 3.4 6.8 8.2 3.7 4.5 3.4 3.5 3.7 6.8 5.8 5.0 2.3 3.4 4.8 3.5 1.1 5.4 4.3 8.5 4.3 4.1 5.2 2.9 4.7 5.3 10.6 3.9 2.4 4.9 3.4 3.5 6.0 4.5 2.9 6.3 20.1 8.9 16.5 9.2 7.3 11.3 11.8 6.7 11.6 7.3 15.1 18.2 17.9 7.6 12.2 15.1 13.5 14.5 14.6 8.5 18.7 15.3 7.7 8.6 25.5 11.5 16.4 9.5 8.4 10.9 13.5 23.6 5.4 11.6 21.3 13.8 16.1 9.6 42.0 7.7 9.8 16.3 33.7 13.6 17.9 9.9 104.8 12.6 8.1 11.0 9.2 14.4 20.0 8.6 6.9 14.0 5.7 7.1 18.7 12.6 59.8 12.3 10.3 13.8 11.8 5.4 12.9 18.3 10.1 7.2 0.7 10.7 13.7 15.8 12.8 10.4 11.6 9.7 9.5 7.9 11.9 0.9 10.5 17.2 2.8 17.8 8.3 3.2 3.2 2.9 3.4 2.7 3.4 3.4 3.5 3.4 2.9 3.9 2.9 7.2 3.2 3.7 0.3 8.6 0.0 9.1 0.0 8.0 2.6 9.7 11.4 1.1 7.2 2.5 5.5 0.0 6.0 3.6 1.8 31.3 18.5 189.0 6.8 14.7 7.3 3.6 3.8 0.7 18.3 12.5 6.0 6.1 4.2 1.3 9.9 6.4 9.9 14.6 6.7 0.9 4.6 0.0 4.1 0.0 393.3 7.8 5.8 0.0 1.9 5.7 7.3 6.2 0.5 1.5 17.0 2.9 3.8 10.2 23.4 3.4 19.6 7.3 2.8 0.0 5.3 6.4 5.8 16.8 12.8 0.0 4.1 5.9 16.2 5.3 8.5 EEPD1 KIAA1706 ENSG00000122547 "Endonuclease/exonuclease/phosphatase family domain containing 1" Q7L9B9 7 36153254-36301538 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 46.9" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 88.0;Oligodendrocytes: 175.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 51.8;neutrophil: 46.4" "Group enriched" "Detected in many" 6 "granulocytes: 51.8;T-cells: 23.0" "Cell line enhanced" "Detected in many" "HDLM-2: 18.3;PC-3: 22.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053668 Approved "Nuclear speckles,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" Vesicles "HPA053668: AB_2682223" "unprognostic (1.30e-1)" "unprognostic (1.19e-1)" "unprognostic (1.54e-3)" "unprognostic (5.21e-3)" "unprognostic (1.14e-1)" "unprognostic (4.76e-1)" "unprognostic (1.19e-2)" "unprognostic (3.75e-2)" "unprognostic (7.89e-2)" "unprognostic (8.77e-2)" "unprognostic (7.74e-2)" "unprognostic (2.62e-1)" "unprognostic (2.82e-1)" "unprognostic (1.07e-2)" "unprognostic (6.52e-2)" "unprognostic (2.23e-2)" "unprognostic (4.59e-2)" 19.5 5.2 9.8 4.0 12.5 8.1 18.3 10.6 14.2 10.2 7.3 12.0 9.9 7.7 3.6 7.1 7.3 11.7 11.1 10.4 10.6 5.9 24.0 8.1 4.6 12.0 12.8 8.5 11.5 2.2 4.4 4.0 12.7 12.5 3.8 1.5 4.1 3.4 46.9 12.8 11.5 5.6 10.3 10.8 17.0 5.3 13.0 12.8 3.1 12.8 3.0 10.9 9.1 19.2 2.2 5.9 1.8 5.6 16.2 3.5 0.1 1.5 7.2 1.1 2.0 1.2 4.5 5.9 1.8 2.2 16.8 2.4 2.4 2.8 1.0 18.3 4.0 0.7 0.5 11.0 1.5 0.9 5.5 7.3 1.7 0.7 0.4 4.5 0.1 4.4 7.3 0.6 1.2 2.3 6.1 14.6 8.2 7.4 22.4 1.6 2.0 1.3 3.6 4.7 4.4 3.1 0.5 0.8 2.2 3.2 1.8 7.0 0.5 2.2 6.5 1.5 1.7 4.3 5.1 0.0 5.4 3.8 1.4 23.1 5.9 51.8 3.0 3.6 5.2 0.3 23.0 6.6 3.2 0.0 5.0 1.5 46.4 3.9 1.6 2.9 11.6 4.2 9.8 12.5 10.6 14.2 10.4 10.6 12.0 12.8 12.7 10.3 13.0 19.2 32.4 0.0 0.5 30.0 1.3 2.7 14.7 1.8 1.8 4.2 4.9 7.2 4.0 34.3 2.1 0.0 20.9 0.2 0.9 10.8 5.9 26.2 17.4 8.4 3.0 14.8 9.6 1.3 28.4 7.4 0.3 4.0 20.9 7.2 8.9 0.9 3.9 16.9 25.3 6.7 88.0 6.2 0.0 5.8 5.5 3.6 5.0 9.8 3.6 45.0 3.8 2.0 0.0 1.5 175.4 16.9 12.6 16.6 0.7 8.7 19.4 1.9 2.6 1.4 6.6 2.1 6.6 0.7 5.4 4.2 4.0 0.5 3.3 6.4 6.2 10.2 EFHB "CFAP21, FLJ25200" ENSG00000163576 "EF-hand domain family member B" Q8N7U6 3 19879472-19947025 "Predicted intracellular proteins" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 6.5;fallopian tube: 17.1;testis: 15.5" "Group enriched" "Detected in many" 4 "Early spermatids: 77.2;Endometrial ciliated cells: 49.9;Late spermatids: 25.7;Respiratory ciliated cells: 93.6;Spermatocytes: 32.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 32 "RPTEC TERT1: 19.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA034835 Approved Vesicles,Cytosol NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" Cytosol Vesicles "HPA034835: " "unprognostic (9.70e-2)" "unprognostic (2.71e-2)" "unprognostic (2.37e-1)" "unprognostic (2.33e-2)" "unprognostic (1.20e-2)" "unprognostic (9.56e-3)" "unprognostic (1.51e-5)" "unprognostic (4.43e-2)" "unprognostic (3.66e-1)" "unprognostic (1.51e-1)" "unprognostic (4.92e-2)" "unprognostic (5.47e-2)" "unprognostic (6.06e-2)" "unprognostic (2.13e-2)" "unprognostic (9.35e-2)" "unprognostic (2.04e-1)" "unprognostic (1.02e-1)" 0.5 0.7 1.6 0.1 1.5 0.2 0.9 1.0 1.4 0.9 2.6 0.2 0.0 1.1 0.6 0.4 17.1 0.6 0.2 1.4 1.6 1.0 0.2 2.0 0.2 6.5 5.0 1.5 0.2 0.4 0.4 0.4 3.4 0.4 0.3 0.8 0.2 0.5 0.2 0.4 0.2 0.5 3.7 0.5 0.2 15.5 1.6 0.3 0.5 0.2 0.3 0.3 0.2 2.2 0.0 0.5 0.2 0.2 0.1 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.3 0.2 0.2 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 19.5 0.1 0.0 0.0 0.0 0.1 0.4 0.1 0.1 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.6 1.5 1.0 1.4 1.4 1.6 6.5 5.0 3.4 3.7 1.6 2.2 1.0 0.0 1.1 5.5 0.3 0.1 0.5 1.9 0.6 0.8 1.8 1.4 0.3 5.7 12.4 3.7 2.1 0.9 1.6 0.5 5.9 0.3 77.2 49.9 1.8 0.7 1.2 3.6 1.7 0.2 0.5 1.3 0.0 1.8 3.8 1.8 1.8 0.6 0.5 1.7 2.2 0.2 4.1 1.3 0.3 25.7 2.5 1.0 0.0 1.9 0.2 5.3 0.0 3.0 1.7 0.6 0.1 2.2 0.0 0.3 1.2 8.3 93.6 0.8 0.0 3.6 1.7 32.7 4.3 0.1 0.1 0.8 0.3 1.0 0.4 0.3 EFNA5 "AF1, EPLG7, LERK7" ENSG00000184349 "Ephrin A5" P52803 5 107376894-107670937 "Cancer-related genes, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 13 "Astrocytes: 291.2;Excitatory neurons: 798.5;Inhibitory neurons: 373.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "gdT-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 35.2;RPTEC TERT1: 50.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013282, HPA054047" Approved Approved Vesicles,Cytosol NA Yes 10000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" "CAB013282: AB_2533353, HPA054047: AB_2682355" "unprognostic (1.67e-1)" "unprognostic (4.04e-2)" "unprognostic (7.52e-2)" "unprognostic (2.15e-3)" "unprognostic (3.98e-3)" "unprognostic (2.74e-2)" "unprognostic (8.91e-4)" "unprognostic (9.46e-3)" "unprognostic (4.92e-1)" "unprognostic (2.28e-3)" "unprognostic (1.26e-3)" "unprognostic (1.47e-1)" "prognostic unfavorable (1.92e-7)" "prognostic unfavorable (3.77e-4)" "unprognostic (1.52e-1)" "unprognostic (2.13e-2)" "unprognostic (1.27e-1)" 4.1 1.1 4.5 2.0 6.5 0.1 4.0 1.3 13.6 10.1 0.0 2.3 0.8 1.1 2.0 7.1 2.9 2.7 6.8 3.1 10.2 3.4 0.3 2.4 0.8 0.9 0.3 4.0 0.5 2.5 2.7 2.4 0.6 4.3 2.3 2.5 5.6 4.7 0.5 9.7 0.8 2.2 0.0 5.3 2.5 1.4 2.1 1.4 1.0 1.4 2.5 3.5 4.8 5.4 12.7 22.2 35.2 0.0 16.7 14.2 3.6 0.3 6.3 4.5 11.6 0.2 13.9 0.0 20.5 2.4 7.1 13.1 19.4 18.0 3.6 0.0 12.9 0.1 11.9 0.0 3.1 0.6 0.0 16.0 15.4 0.0 14.4 3.9 13.8 0.0 0.0 0.0 8.3 12.0 0.0 0.0 4.6 0.1 1.9 0.0 16.9 0.4 50.9 15.5 5.8 14.7 6.0 8.9 3.8 11.2 3.9 2.2 0.2 28.3 5.0 17.4 7.1 1.2 0.0 8.3 12.4 0.8 31.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.4 0.1 0.7 0.0 0.0 0.0 0.1 4.5 6.5 1.3 13.6 3.1 10.2 0.9 0.3 0.6 0.0 2.1 5.4 1.1 9.6 24.4 291.2 0.0 15.9 22.5 18.5 6.2 4.3 11.8 8.5 30.6 11.5 26.0 14.7 0.0 20.3 3.3 4.3 23.5 1.7 1.8 3.2 14.8 8.2 12.0 0.0 798.5 1.3 3.3 16.9 5.6 6.3 0.0 0.1 9.7 0.0 1.7 6.7 373.1 8.5 18.3 0.3 7.0 3.7 18.3 0.4 8.8 37.5 3.6 4.7 2.1 26.2 8.7 13.9 4.9 21.8 1.7 14.1 0.0 0.1 19.6 1.4 0.0 1.3 3.7 0.1 4.0 14.9 24.2 3.8 2.2 2.3 5.9 23.1 EFTUD2 "SNRNP116, Snrp116, Snu114, U5-116KD" ENSG00000108883 "Elongation factor Tu GTP binding domain containing 2" Q15029 17 44849948-44899445 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022021 Supported Approved Nucleoplasm,Vesicles,Cytosol NA NA 94000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Vesicles, Cytosol" "HPA022021: AB_1848032" "unprognostic (4.28e-2)" "unprognostic (4.12e-2)" "unprognostic (1.98e-3)" "unprognostic (1.32e-1)" "unprognostic (1.94e-1)" "unprognostic (4.98e-2)" "prognostic unfavorable (2.71e-6)" "unprognostic (6.94e-2)" "unprognostic (4.52e-1)" "unprognostic (2.37e-1)" "unprognostic (4.11e-3)" "unprognostic (5.19e-2)" "unprognostic (5.48e-3)" "unprognostic (1.62e-2)" "unprognostic (5.30e-2)" "unprognostic (3.60e-1)" "unprognostic (1.53e-2)" 23.6 30.7 26.7 31.3 27.2 37.4 22.4 24.6 28.0 17.6 27.9 26.5 21.6 19.4 18.8 33.1 25.0 16.3 35.3 28.0 26.3 26.1 26.2 22.6 35.5 25.6 26.1 17.6 24.0 27.9 13.2 28.6 26.4 17.8 28.8 15.5 22.5 18.6 65.8 28.5 22.8 23.5 25.1 29.8 22.5 27.5 27.3 41.0 21.2 38.3 46.5 28.8 20.3 26.6 88.7 173.6 82.8 134.9 61.9 60.9 97.1 68.7 91.4 169.6 146.0 134.6 73.9 152.1 79.0 87.1 130.3 98.6 181.5 120.2 196.2 153.9 150.8 150.9 100.9 144.5 68.2 179.9 107.5 66.5 67.4 157.2 85.0 65.2 149.1 134.8 189.6 57.8 98.0 88.2 182.3 118.6 85.7 206.8 143.1 126.1 168.1 132.0 97.0 97.8 135.7 81.1 67.7 49.5 73.9 120.6 131.6 112.2 91.4 126.5 97.4 77.7 176.3 60.2 81.4 150.0 101.6 98.4 132.0 42.7 84.3 85.9 37.2 81.6 41.7 32.3 32.9 36.1 82.8 31.3 28.8 32.2 13.0 44.2 85.0 35.5 35.2 70.7 26.7 27.2 24.6 28.0 28.0 26.3 25.6 26.1 26.4 25.1 27.3 26.6 11.3 0.0 14.0 11.1 18.1 11.7 12.2 15.1 13.6 14.7 14.1 11.8 21.1 22.8 15.3 18.4 33.3 34.5 14.0 15.6 3.9 29.4 12.5 17.8 17.9 21.4 10.8 24.8 17.5 26.7 30.9 14.0 18.3 18.8 19.7 22.6 21.8 22.4 38.5 26.9 17.2 13.4 16.2 30.1 17.5 6.5 12.8 26.2 5.4 12.2 46.7 12.0 21.6 6.0 15.5 27.7 12.0 9.1 20.3 14.5 15.9 13.2 17.4 18.0 19.7 14.8 14.8 28.2 43.3 16.0 14.6 27.2 16.3 21.4 22.2 12.5 EGFL8 "C6orf8, NG3" ENSG00000241404 "EGF like domain multiple 8" Q99944 6 32164595-32168281 "Metabolic proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 6.4;Granulosa cells: 10.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 3.2;SK-MEL-30: 3.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA061173 Uncertain Approved "Nuclear speckles,Vesicles" "Secreted - unknown location" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Nuclear speckles" "HPA061173: AB_2684443" "unprognostic (7.13e-2)" "unprognostic (1.86e-1)" "unprognostic (6.79e-3)" "unprognostic (3.64e-1)" "unprognostic (1.30e-1)" "unprognostic (7.60e-4)" "unprognostic (3.42e-2)" "unprognostic (2.49e-1)" "unprognostic (6.42e-3)" "unprognostic (1.97e-1)" "unprognostic (7.60e-3)" "unprognostic (8.11e-3)" "unprognostic (1.07e-4)" "unprognostic (1.11e-1)" "unprognostic (6.79e-2)" "unprognostic (1.21e-1)" "unprognostic (3.29e-2)" 13.3 7.2 3.8 0.5 3.5 1.1 13.6 3.6 5.7 23.4 4.1 19.8 0.6 10.0 0.8 12.3 16.3 3.0 14.2 3.9 3.9 16.3 7.4 9.4 0.3 3.8 3.9 31.2 5.1 0.4 8.2 2.9 3.7 16.9 0.5 0.0 7.9 1.4 3.8 12.8 8.8 0.3 3.8 7.9 10.2 4.4 4.1 0.6 8.7 2.5 0.2 13.5 17.2 3.8 0.2 0.1 0.4 1.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 1.1 0.4 0.0 0.0 0.0 0.5 0.0 0.3 3.2 0.0 0.0 0.3 0.0 0.4 0.2 0.1 0.0 0.2 0.7 0.5 0.0 0.0 0.6 1.0 1.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 3.4 0.0 1.0 0.7 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 3.5 3.6 5.7 3.9 3.9 3.8 3.9 3.7 3.8 4.1 3.8 1.2 6.4 4.1 0.0 0.3 1.5 0.6 0.3 4.6 1.5 0.5 0.3 0.1 0.0 1.6 1.8 2.1 0.8 0.6 0.2 0.0 0.4 0.1 1.0 1.9 1.7 0.0 1.7 0.0 0.2 0.4 1.5 4.6 1.3 0.0 10.4 3.3 0.3 0.2 0.0 0.0 1.1 0.0 0.6 1.6 0.2 3.7 0.7 0.0 0.0 0.0 0.9 3.1 0.0 0.0 0.3 0.2 1.2 2.1 0.7 0.4 0.1 1.6 1.5 0.0 2.0 1.5 0.5 0.4 4.0 2.3 0.8 0.9 1.5 1.3 0.5 EGR3 PILOT ENSG00000179388 "Early growth response 3" Q06889 8 22687659-22693480 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 47.2;skin 1: 45.6" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 284.3;Glandular and luminal cells: 116.6;granulocytes: 108.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 47.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 5.5;HMC-1: 9.5;MCF7: 31.9;SK-MEL-30: 22.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 9 "amygdala: 19.3;basal ganglia: 52.5;cerebral cortex: 47.8;hippocampal formation: 41.3;olfactory bulb: 33.7" "HPA006206, CAB009373" Uncertain Uncertain Nucleoplasm,Vesicles NA NA "Cluster 31: Skin - Epidermis development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Vesicles "CAB009373: AB_2097202, HPA006206: AB_10602491" "prognostic favorable (1.83e-4)" "unprognostic (1.15e-1)" "unprognostic (2.40e-1)" "unprognostic (1.21e-1)" "unprognostic (2.89e-2)" "unprognostic (4.07e-2)" "unprognostic (1.00e-1)" "unprognostic (6.44e-2)" "prognostic favorable (4.78e-4)" "unprognostic (3.48e-2)" "unprognostic (5.14e-2)" "unprognostic (1.61e-1)" "unprognostic (2.87e-2)" "unprognostic (2.11e-2)" "unprognostic (4.72e-2)" "unprognostic (2.35e-2)" "unprognostic (1.07e-2)" 29.0 24.5 7.7 19.0 9.9 10.1 10.3 0.6 47.2 9.5 0.0 4.6 1.5 5.6 0.4 5.9 17.3 30.0 12.1 16.1 0.0 5.8 2.9 5.8 11.4 5.1 0.0 15.3 4.5 13.8 6.8 1.0 2.0 14.4 3.2 4.5 3.1 0.9 1.9 45.6 3.9 12.5 1.3 3.3 6.5 5.4 0.0 19.5 8.4 3.2 5.9 14.8 3.6 5.8 0.2 0.0 0.2 0.3 1.8 5.5 0.1 0.6 0.6 0.0 0.1 0.1 0.0 0.1 0.1 1.3 0.4 0.5 0.2 0.2 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 9.5 0.6 0.2 0.2 0.0 0.8 0.1 0.2 0.3 0.1 0.0 31.9 0.0 0.2 0.1 2.2 0.1 0.1 0.1 0.8 0.0 0.0 0.0 0.1 0.5 0.0 22.5 0.3 1.4 0.1 0.0 0.3 0.1 0.2 0.4 0.4 0.1 0.0 0.9 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 7.7 9.9 0.6 47.2 16.1 0.0 5.1 0.0 2.0 1.3 0.0 5.8 80.2 6.4 11.2 0.3 46.7 23.1 31.9 43.8 39.3 2.3 73.0 68.2 47.1 0.0 12.2 0.0 0.0 1.3 9.3 3.5 0.0 3.3 18.4 47.1 52.7 36.5 284.3 0.0 16.0 4.2 1.3 33.9 35.2 116.6 108.7 21.8 37.5 0.5 4.7 0.0 0.9 19.2 8.2 19.0 20.3 11.6 3.1 27.8 21.4 3.7 0.0 5.1 0.0 1.0 0.7 4.5 2.2 0.4 3.7 16.1 0.2 0.1 5.7 1.3 0.0 41.3 35.9 0.3 0.2 16.5 50.0 9.7 11.5 6.5 7.0 9.8 EHBP1L1 "DKFZp762C186, TANGERIN" ENSG00000173442 "EH domain binding protein 1 like 1" Q8N3D4 11 65576046-65592650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 255.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 79.1;Kupffer cells: 79.7;Macrophages: 67.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039479, HPA073476" Enhanced Approved "Vesicles,Plasma membrane" NA NA 110000 "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Plasma membrane" "HPA039479: AB_10795678, HPA073476: " "unprognostic (1.87e-2)" "unprognostic (1.10e-1)" "unprognostic (1.48e-2)" "unprognostic (7.73e-3)" "unprognostic (1.31e-1)" "unprognostic (2.84e-1)" "unprognostic (2.41e-3)" "unprognostic (2.35e-1)" "unprognostic (1.01e-1)" "unprognostic (1.84e-2)" "unprognostic (3.36e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (1.45e-4)" "unprognostic (6.10e-3)" "unprognostic (5.02e-2)" "unprognostic (3.50e-2)" "unprognostic (1.10e-1)" 27.2 9.9 7.5 51.9 6.2 59.7 21.5 5.9 9.4 35.9 7.3 108.1 26.0 56.1 5.7 45.4 48.0 18.0 45.6 7.1 6.3 17.7 10.8 39.6 30.7 9.8 8.1 19.6 8.1 4.1 9.8 16.3 7.7 45.2 12.2 0.4 22.9 39.5 255.7 22.6 46.6 32.8 8.0 73.3 41.0 7.3 9.4 14.5 13.0 70.7 16.6 71.3 40.8 9.0 40.6 41.0 1.3 21.8 10.5 26.4 8.2 31.4 22.9 14.8 7.8 13.7 34.9 14.0 52.4 45.8 41.2 55.9 7.6 29.7 3.4 39.3 1.2 32.4 51.0 12.0 10.0 7.1 30.1 22.7 19.8 37.2 6.8 26.9 15.2 20.8 50.5 55.9 13.8 34.5 12.4 27.5 1.8 15.1 34.8 33.6 0.2 46.8 13.7 20.0 0.9 17.2 17.4 15.2 32.9 3.0 21.9 33.7 26.3 40.3 42.9 57.3 0.6 98.5 66.6 7.3 60.2 18.8 23.9 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 7.5 6.2 5.9 9.4 7.1 6.3 9.8 8.1 7.7 8.0 9.4 9.0 33.1 0.0 6.9 6.2 23.9 10.1 8.5 2.9 15.9 1.4 12.2 14.2 22.0 7.2 7.4 1.8 0.0 3.4 27.3 79.1 0.0 3.6 0.2 11.9 12.2 26.0 4.2 61.6 4.4 5.1 1.4 13.8 61.2 14.2 2.5 5.3 18.9 5.7 32.6 0.0 2.2 16.3 2.0 79.7 33.9 1.7 11.5 67.6 7.2 15.0 49.1 0.7 20.6 1.5 1.3 27.8 53.0 38.0 19.5 11.6 19.5 0.4 8.6 1.1 26.3 27.3 30.7 2.7 5.9 15.3 14.8 2.6 23.2 23.0 21.9 17.0 EIF1AD "haponin, MGC11102" ENSG00000175376 "Eukaryotic translation initiation factor 1A domain containing" Q8N9N8 11 65996545-66002176 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054991, HPA058735" Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 16: U-266 - Nucleosome" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Vesicles" Cytosol "HPA054991: AB_2682664, HPA058735: AB_2683802" "unprognostic (1.11e-1)" "unprognostic (8.83e-2)" "unprognostic (3.03e-1)" "prognostic unfavorable (3.59e-5)" "unprognostic (1.30e-2)" "unprognostic (5.69e-2)" "prognostic unfavorable (8.63e-5)" "unprognostic (1.86e-2)" "unprognostic (1.17e-1)" "unprognostic (8.76e-2)" "unprognostic (1.36e-3)" "unprognostic (2.31e-1)" "unprognostic (1.59e-3)" "unprognostic (7.63e-3)" "unprognostic (1.40e-1)" "unprognostic (1.28e-3)" "unprognostic (3.96e-1)" 15.7 17.7 15.3 19.9 15.8 44.6 16.0 18.7 19.8 13.1 14.4 15.8 15.1 15.9 16.2 21.0 15.3 13.0 17.1 16.4 17.7 15.2 17.3 15.0 23.4 16.1 15.7 20.4 19.2 17.1 16.6 21.1 16.3 13.4 14.7 16.6 16.8 14.9 27.2 23.1 16.9 14.8 14.8 20.0 16.1 19.4 17.3 19.9 13.8 23.3 27.6 17.1 14.5 18.4 51.0 43.9 35.0 35.9 27.6 28.8 32.8 36.4 34.6 44.2 37.7 44.8 47.5 38.2 62.6 41.2 38.0 34.9 42.2 48.8 41.5 35.1 21.7 54.4 52.0 46.4 33.7 50.3 41.8 24.1 41.9 65.3 44.1 31.2 31.0 40.9 81.1 54.4 64.7 68.7 46.6 55.1 25.9 23.3 47.5 50.3 35.9 75.0 25.6 31.8 26.5 31.2 39.3 54.7 41.5 28.1 53.1 31.0 36.5 59.7 39.9 47.8 36.1 66.7 85.5 79.8 42.9 33.8 39.5 52.6 20.5 13.5 17.7 16.6 13.6 19.4 15.0 13.0 21.3 19.0 14.1 13.5 13.1 16.4 21.3 12.7 15.3 13.3 15.3 15.8 18.7 19.8 16.4 17.7 16.1 15.7 16.3 14.8 17.3 18.4 8.2 3.2 5.4 3.3 16.2 37.7 12.2 13.4 12.5 7.2 14.2 9.1 16.2 14.3 7.3 5.5 14.6 16.3 17.7 11.6 15.6 12.7 18.3 9.0 8.3 11.6 2.4 21.0 3.0 13.1 23.0 11.4 7.1 10.5 12.7 31.7 16.4 16.5 24.5 11.8 2.8 11.2 6.1 10.4 29.5 14.3 12.2 14.4 12.4 1.0 17.6 10.5 17.5 5.5 4.5 29.0 15.2 5.7 22.6 13.2 13.8 15.7 10.6 18.5 6.6 9.8 27.0 31.3 23.2 15.7 48.9 25.3 16.2 7.4 10.9 13.2 EIF2B3 "EIF-2B, EIF2Bgamma" ENSG00000070785 "Eukaryotic translation initiation factor 2B subunit gamma" Q9NR50 1 44850522-44986722 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024213, HPA024218, HPA024219" Supported Supported Vesicles,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Vesicles, Cytosol" "HPA024213: AB_1848067, HPA024218: AB_1848068, HPA024219: AB_1848069" "unprognostic (2.12e-2)" "unprognostic (7.49e-2)" "unprognostic (4.37e-3)" "unprognostic (5.14e-2)" "unprognostic (1.57e-2)" "unprognostic (4.45e-2)" "prognostic unfavorable (1.73e-5)" "unprognostic (4.55e-2)" "unprognostic (1.14e-2)" "unprognostic (7.22e-2)" "unprognostic (2.16e-1)" "unprognostic (1.36e-1)" "unprognostic (5.38e-2)" "unprognostic (6.98e-2)" "unprognostic (7.80e-2)" "unprognostic (5.69e-3)" "unprognostic (2.73e-2)" 23.6 27.2 11.4 11.6 10.9 10.9 21.9 13.2 15.6 18.7 10.1 17.5 8.6 17.0 12.5 17.4 16.3 9.6 40.6 11.2 11.6 15.4 24.7 13.5 14.3 11.9 12.1 18.2 16.9 30.0 15.8 9.7 12.8 15.0 13.4 19.0 25.1 13.7 77.0 17.6 10.7 19.4 11.0 14.9 14.2 19.3 11.2 13.3 12.5 48.0 14.5 17.7 17.1 14.0 35.4 26.9 30.9 25.5 36.3 43.1 36.2 56.1 42.2 56.5 52.9 39.0 20.7 90.6 39.9 43.2 45.0 20.6 65.3 48.6 69.5 32.5 58.1 44.3 29.3 38.4 46.2 71.2 24.3 29.3 25.8 61.0 69.9 26.5 52.8 30.1 106.1 31.6 62.3 23.1 69.7 30.2 42.0 38.8 52.7 54.7 51.3 65.7 28.7 15.7 53.2 20.5 55.1 63.8 37.4 40.7 24.7 32.8 28.3 35.9 42.9 53.4 73.7 31.6 37.9 68.9 27.9 59.5 43.1 1.6 23.4 3.9 18.6 37.2 22.8 14.8 18.3 21.1 37.0 18.9 22.9 23.6 2.1 25.5 33.1 25.3 17.6 21.4 11.4 10.9 13.2 15.6 11.2 11.6 11.9 12.1 12.8 11.0 11.2 14.0 13.9 6.4 22.0 24.8 15.8 13.8 19.0 33.0 10.8 15.1 15.8 16.8 79.2 15.7 24.9 5.5 20.9 25.1 12.1 4.5 29.4 18.9 26.1 17.0 23.0 14.4 3.6 15.3 39.9 15.8 22.6 22.6 13.7 11.5 25.9 21.1 3.9 22.6 24.8 21.9 44.5 7.0 20.3 10.7 11.2 11.3 26.4 15.4 17.8 26.2 30.1 21.7 10.3 29.1 35.7 13.7 6.9 25.2 22.6 17.1 5.7 23.1 34.2 21.8 26.3 19.7 45.4 45.5 23.6 17.1 14.9 14.9 13.5 40.4 9.4 13.9 EIF4ENIF1 "2610509L04Rik, 4E-T, Clast4, FLJ21601" ENSG00000184708 "Eukaryotic translation initiation factor 4E nuclear import factor 1" Q9NRA8 22 31436977-31496108 "Plasma proteins, Predicted intracellular proteins" "Protein transport, RNA-mediated gene silencing, Translation regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 54.6;Late spermatids: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001619, HPA002078" Enhanced Enhanced Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA001619: AB_1078727, HPA002078: AB_1078728" "unprognostic (1.16e-1)" "unprognostic (1.63e-1)" "unprognostic (2.40e-2)" "unprognostic (3.01e-2)" "unprognostic (1.53e-1)" "unprognostic (6.72e-2)" "unprognostic (2.28e-3)" "unprognostic (1.30e-2)" "unprognostic (4.95e-2)" "unprognostic (9.92e-2)" "unprognostic (1.24e-1)" "unprognostic (1.80e-1)" "prognostic favorable (1.57e-4)" "unprognostic (2.30e-1)" "unprognostic (1.92e-1)" "unprognostic (7.32e-2)" "unprognostic (2.45e-2)" 12.5 11.9 14.3 10.4 14.8 14.3 11.9 19.7 17.3 15.9 11.4 19.4 11.4 15.0 13.0 14.0 13.8 7.8 13.2 15.3 15.0 12.3 8.4 12.1 12.6 13.6 14.7 15.0 10.5 16.7 10.8 13.6 14.3 13.5 11.5 18.0 12.1 13.2 20.2 15.7 11.8 12.1 11.6 12.3 12.3 34.7 13.8 12.9 13.5 14.5 14.9 15.6 14.3 17.3 19.8 11.6 29.4 16.0 16.1 14.2 11.7 13.7 16.8 21.4 19.8 13.4 7.0 25.3 7.9 20.7 14.3 19.1 26.9 12.5 19.7 20.2 27.0 10.3 20.0 15.4 16.7 41.0 17.9 16.6 16.9 15.8 17.8 19.5 18.4 14.8 25.4 27.0 20.3 22.4 27.8 20.3 13.5 18.3 9.5 31.1 24.5 26.0 21.7 14.7 22.6 20.9 18.9 15.4 14.5 19.4 16.4 16.1 20.5 14.3 18.6 14.4 15.5 19.3 20.4 25.1 13.7 14.8 17.1 1.3 2.4 1.2 3.4 3.0 3.5 4.8 1.8 3.3 2.2 2.0 1.8 3.2 2.0 1.0 8.1 4.4 1.4 1.9 14.3 14.8 19.7 17.3 15.3 15.0 13.6 14.7 14.3 11.6 13.8 17.3 8.4 12.8 15.2 23.2 10.6 7.4 7.3 6.2 15.4 18.0 9.6 8.9 22.7 10.0 8.5 12.9 12.5 9.8 13.8 8.6 9.8 8.9 54.6 8.0 12.8 10.2 12.0 12.4 21.0 6.4 5.5 8.1 12.2 13.0 6.3 23.1 11.0 8.9 8.0 18.5 20.5 10.8 8.2 9.5 6.2 98.9 14.6 7.5 7.2 13.1 14.5 8.1 14.4 20.1 20.2 10.2 3.6 15.4 10.3 10.7 5.7 9.4 6.3 13.7 6.6 11.8 11.0 38.7 13.3 10.7 10.5 6.7 8.2 9.0 8.1 8.0 EIF5A2 ENSG00000163577 "Eukaryotic translation initiation factor 5A2" Q9GZV4 3 170888418-170908644 "Predicted intracellular proteins, Transporters" "mRNA transport, Protein biosynthesis, Protein transport, Translocation, Transport" "Elongation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 28.3" "Group enriched" "Detected in many" 12 "Early spermatids: 353.0;Late spermatids: 977.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029090 Approved Supported Vesicles NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 78: Testis - Spermatogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA029090: AB_10671359" "unprognostic (2.41e-1)" "unprognostic (2.42e-1)" "unprognostic (4.05e-1)" "unprognostic (5.75e-2)" "unprognostic (1.27e-1)" "prognostic unfavorable (7.42e-4)" "unprognostic (1.11e-3)" "unprognostic (1.47e-1)" "unprognostic (3.72e-1)" "unprognostic (1.08e-1)" "unprognostic (1.06e-1)" "unprognostic (1.79e-1)" "unprognostic (2.66e-2)" "unprognostic (3.45e-2)" "unprognostic (5.92e-2)" "unprognostic (1.64e-2)" "unprognostic (4.29e-3)" 4.1 2.7 1.9 3.1 2.8 4.2 2.9 5.8 6.1 3.1 1.9 3.4 1.7 4.5 1.3 2.9 2.4 3.5 4.0 1.9 5.4 5.0 1.6 2.2 2.8 7.2 4.6 4.4 3.3 3.7 1.8 1.8 8.2 2.6 2.6 2.8 1.9 3.0 1.3 1.9 1.6 7.2 4.1 2.3 9.1 28.3 5.5 4.3 2.2 3.1 3.1 3.5 2.0 7.2 22.7 11.6 4.2 5.9 21.7 14.2 10.0 17.1 22.3 17.4 25.1 23.6 14.4 14.2 30.9 23.4 38.9 7.4 13.4 6.0 21.9 15.8 5.8 6.9 4.6 7.5 14.6 18.2 19.9 16.6 8.7 26.3 21.4 24.2 9.1 3.7 5.8 0.1 28.7 7.6 8.1 7.9 8.1 17.5 7.8 0.0 12.0 0.0 7.3 4.0 3.4 6.4 17.7 4.6 14.4 6.5 10.0 11.9 12.0 21.2 15.0 44.8 38.9 21.6 0.3 33.3 7.2 6.2 15.4 14.9 1.4 1.5 12.4 1.5 8.7 2.2 8.4 11.9 1.0 3.5 5.0 8.3 0.7 8.8 1.4 1.0 11.3 5.0 1.9 2.8 5.8 6.1 1.9 5.4 7.2 4.6 8.2 4.1 5.5 7.2 16.6 0.0 0.5 4.9 4.4 17.1 8.5 7.8 10.8 2.5 2.1 2.7 9.5 0.0 1.8 1.8 0.0 1.2 18.1 1.6 1.9 6.4 353.0 0.9 7.7 12.8 4.9 2.1 7.1 7.5 1.9 11.7 8.6 0.6 2.5 2.6 3.3 2.5 8.9 0.0 8.8 0.8 2.0 3.8 7.2 977.9 12.8 4.5 10.6 3.7 7.9 8.0 28.8 4.0 10.1 19.6 6.1 11.3 3.7 8.2 1.7 21.1 3.4 2.7 46.0 9.6 11.6 54.3 10.0 2.3 21.6 0.7 15.7 2.2 1.8 5.7 ELAVL4 "HUD, PNEM" ENSG00000162374 "ELAV like RNA binding protein 4" P26378 1 50024029-50203772 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 52.8" "Group enriched" "Detected in some" 4 "Early spermatids: 155.5;Excitatory neurons: 158.7;Inhibitory neurons: 109.7;Late spermatids: 159.4;Oligodendrocyte precursor cells: 75.4" "Cancer enriched" "Detected in some" 4 "glioma: 2.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.1" "Lineage enriched" "Detected in single" 5 "monocytes: 1.1" "Cell line enriched" "Detected in some" 17 "SH-SY5Y: 157.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004442, HPA043047" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "CAB004442: AB_627765, HPA043047: AB_2732502" "unprognostic (1.25e-1)" "unprognostic (6.63e-3)" "unprognostic (4.43e-2)" "unprognostic (1.13e-1)" "unprognostic (1.95e-1)" "unprognostic (3.28e-2)" "unprognostic (3.83e-4)" "unprognostic (4.52e-2)" "unprognostic (2.63e-1)" "unprognostic (2.75e-1)" "unprognostic (3.75e-3)" "unprognostic (7.91e-2)" "unprognostic (2.39e-3)" "unprognostic (7.83e-2)" "unprognostic (2.81e-2)" "unprognostic (4.13e-2)" "unprognostic (7.43e-2)" 0.1 11.2 13.9 2.4 18.0 0.0 0.2 7.4 52.8 0.0 0.0 2.2 1.4 0.0 0.0 0.2 0.1 0.1 0.2 20.0 18.5 0.1 0.1 0.3 0.2 36.5 14.0 0.0 2.3 0.0 3.4 0.2 31.7 0.1 2.8 3.9 0.2 0.1 0.0 0.4 2.2 1.1 2.0 0.2 1.0 8.5 11.4 0.9 0.0 0.0 0.2 0.1 0.2 17.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.2 157.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.0 13.9 18.0 7.4 52.8 20.0 18.5 36.5 14.0 31.7 2.0 11.4 17.4 0.1 0.0 0.0 7.2 0.1 0.8 0.0 0.0 0.0 3.9 0.1 0.3 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 155.5 0.0 0.0 0.3 32.9 0.0 158.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 109.7 0.1 4.1 4.0 5.0 159.4 1.5 3.1 1.8 22.5 0.0 1.5 0.0 75.4 5.9 0.3 0.0 0.4 0.0 0.1 0.0 0.1 0.0 3.4 0.0 0.0 0.1 8.9 11.8 0.0 0.9 0.1 0.2 0.0 0.1 0.1 ELFN2 "dJ63G5.3, KIAA1904, LRRC62, PPP1R29" ENSG00000166897 "Extracellular leucine rich repeat and fibronectin type III domain containing 2" Q5R3F8 22 37367960-37427479 "Predicted membrane proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 18.2;retina: 6.1" "Group enriched" "Detected in some" 5 "Bipolar cells: 45.5;Excitatory neurons: 11.6;Inhibitory neurons: 16.2;Oligodendrocyte precursor cells: 36.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 18.2;basal ganglia: 13.8;cerebral cortex: 17.5;hippocampal formation: 16.6;white matter: 4.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 12.0;CAPAN-2: 11.2;GAMG: 12.3;RPMI-8226: 11.7;RPTEC TERT1: 21.5;U-2 OS: 24.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000781 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Vesicles" "HPA000781: AB_1079280" "unprognostic (2.74e-1)" "unprognostic (6.81e-2)" "unprognostic (2.80e-2)" "unprognostic (1.31e-5)" "unprognostic (3.28e-1)" "unprognostic (2.51e-2)" "unprognostic (7.76e-2)" "unprognostic (4.25e-2)" "unprognostic (6.05e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (4.51e-1)" "prognostic unfavorable (7.21e-4)" "unprognostic (1.29e-1)" "unprognostic (1.95e-1)" "unprognostic (1.77e-1)" "unprognostic (1.95e-1)" 0.0 0.6 18.2 0.0 13.8 0.0 0.0 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 16.6 0.9 0.2 0.2 0.6 0.0 2.7 2.7 0.0 0.2 0.0 0.0 0.0 1.9 0.6 0.0 6.1 0.0 0.0 0.0 0.3 0.0 0.0 2.8 0.0 0.1 1.7 2.2 2.2 0.0 0.0 0.0 0.0 0.0 4.8 12.0 4.9 0.0 0.0 0.0 0.9 0.0 5.3 2.8 1.2 0.1 1.9 11.2 0.2 6.8 3.8 12.3 8.2 0.6 1.1 0.1 0.2 0.1 0.0 5.7 0.0 0.2 0.0 0.1 0.9 0.1 0.4 1.6 4.5 0.4 0.2 0.0 0.0 0.4 0.5 0.0 0.0 0.3 7.1 10.6 0.1 0.1 11.7 21.5 0.1 1.0 0.0 4.9 6.2 0.0 0.1 0.0 0.1 0.5 0.0 24.1 0.2 3.5 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 13.8 0.0 17.5 16.6 0.9 2.7 2.7 1.9 2.8 2.2 4.8 0.1 0.0 5.1 1.3 0.5 0.1 0.0 0.9 0.0 45.5 0.0 0.0 0.0 1.5 0.2 0.0 4.2 0.0 0.0 0.0 0.0 0.1 0.7 0.2 0.0 0.2 0.0 0.0 11.6 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 3.3 16.2 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 1.9 0.0 0.9 0.0 36.7 0.9 0.1 0.0 0.0 0.0 0.3 0.0 0.5 0.6 2.0 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ELOC "SIII, TCEB1" ENSG00000154582 "Elongin C" Q15369 8 73939169-73972287 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 266.1;Extravillous trophoblasts: 326.2;Hofbauer cells: 313.7;Pancreatic endocrine cells: 317.3;Proximal tubular cells: 341.3;Syncytiotrophoblasts: 332.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078113 Approved "Nucleoli,Vesicles,Cell Junctions" NA NA 140000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 7: Non-specific - Mitochondria" Vesicles "Nucleoli, Cell Junctions" "HPA078113: AB_2686877" "prognostic unfavorable (6.48e-4)" "unprognostic (1.60e-1)" "unprognostic (3.14e-1)" "unprognostic (2.83e-2)" "unprognostic (2.46e-2)" "unprognostic (8.02e-3)" "unprognostic (5.84e-3)" "unprognostic (2.19e-2)" "unprognostic (1.77e-1)" "unprognostic (6.99e-3)" "unprognostic (4.02e-3)" "unprognostic (3.33e-2)" "unprognostic (2.77e-3)" "unprognostic (3.84e-2)" "unprognostic (5.33e-2)" "unprognostic (1.67e-1)" "unprognostic (8.95e-2)" 78.3 83.9 86.5 45.0 89.6 93.1 59.9 88.6 116.1 47.9 79.8 61.3 30.2 48.1 67.0 75.3 46.2 39.3 141.0 92.5 85.3 97.2 76.0 62.0 52.5 83.6 83.9 46.1 41.1 58.5 57.2 56.0 83.9 45.2 44.8 69.4 46.7 43.7 190.3 48.4 40.7 54.8 84.2 48.2 57.3 111.2 85.1 64.4 43.3 125.6 65.7 69.3 52.0 89.5 211.2 169.2 151.1 110.2 113.0 146.7 108.1 203.6 165.3 194.8 199.0 151.1 178.2 106.3 160.7 181.9 263.4 147.2 168.7 203.6 256.8 123.2 141.5 185.7 174.2 243.0 147.3 120.4 133.6 149.4 159.9 177.0 226.8 144.2 184.8 180.2 166.2 137.8 260.2 155.9 311.7 214.9 137.5 341.9 271.8 111.9 95.1 100.8 216.2 181.9 142.1 134.3 85.2 458.9 202.4 155.1 169.2 127.9 142.2 140.1 160.6 156.1 208.1 155.6 204.5 198.9 169.6 130.2 175.0 138.6 66.4 85.6 62.0 78.6 68.3 83.1 74.2 70.8 73.6 73.9 66.5 67.5 79.8 73.4 77.3 118.4 99.1 60.0 86.5 89.6 88.6 116.1 92.5 85.3 83.6 83.9 83.9 84.2 85.1 89.5 236.0 67.3 98.9 0.0 24.8 0.0 0.0 0.0 0.0 0.0 147.6 185.4 0.0 0.0 49.5 119.5 0.0 220.1 74.5 0.0 266.1 216.7 0.0 147.9 98.9 77.1 0.0 0.0 0.0 227.2 326.2 66.0 0.0 168.8 69.4 65.9 0.0 0.0 313.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 80.9 0.0 0.0 112.7 0.0 0.0 0.0 0.0 317.3 0.0 0.0 12.1 0.0 0.0 341.3 63.4 0.0 0.0 0.0 78.2 0.0 0.0 0.0 0.0 332.5 40.7 98.8 0.0 0.0 ELOVL3 CIG-30 ENSG00000119915 "ELOVL fatty acid elongase 3" Q9HB03 10 102226299-102229589 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skin 1: 30.5" "Cell type enhanced" "Detected in some" "Adipocytes: 2.5;Breast myoepithelial cells: 3.2;Skeletal myocytes: 5.0;Spermatogonia: 3.4;Theca cells: 2.2" "Cancer enhanced" "Detected in many" "testis cancer: 10.6" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 10 "classical monocyte: 7.1;intermediate monocyte: 2.4;myeloid DC: 2.0;non-classical monocyte: 5.9" "Group enriched" "Detected in many" 10 "dendritic cells: 2.0;monocytes: 7.1" "Cell line enhanced" "Detected in many" "ASC diff: 9.5;ASC TERT1: 9.4;HSkMC: 13.9;NB-4: 11.6;SiHa: 22.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA036236 Enhanced Approved Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Cytosol" "HPA036236: AB_10601550" "unprognostic (1.52e-2)" "unprognostic (6.76e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (6.25e-5)" "unprognostic (8.23e-3)" "unprognostic (9.82e-2)" "unprognostic (2.17e-4)" "unprognostic (4.27e-2)" "unprognostic (2.28e-1)" "unprognostic (5.56e-2)" "unprognostic (1.84e-2)" "unprognostic (5.36e-3)" "unprognostic (2.66e-9)" "unprognostic (1.04e-1)" "unprognostic (2.81e-1)" "unprognostic (1.97e-1)" "unprognostic (1.79e-1)" 3.2 0.7 1.0 0.3 0.8 1.8 3.5 0.5 1.3 0.1 0.3 0.1 0.0 0.1 0.2 0.2 0.2 0.2 0.2 1.0 0.4 0.8 0.0 1.0 0.1 0.4 0.9 0.1 0.0 0.1 0.0 0.9 0.4 0.2 0.1 0.1 0.3 0.1 0.2 30.5 0.2 0.0 0.4 0.8 0.1 1.2 0.4 0.0 0.0 0.3 0.0 0.2 0.3 0.5 3.2 0.2 0.2 7.8 9.5 9.4 2.8 0.1 0.3 0.4 0.5 0.5 3.0 0.0 0.3 0.0 0.0 0.1 5.9 0.1 0.5 0.0 0.0 0.2 0.4 0.8 0.3 0.0 0.1 13.9 1.6 3.6 0.0 0.0 0.0 0.9 0.1 3.5 0.8 0.0 0.0 11.6 0.1 1.1 1.0 0.0 5.1 0.0 2.0 0.1 0.0 0.4 22.6 0.9 0.7 0.6 8.1 2.7 0.0 1.5 0.0 0.3 0.3 0.5 7.2 0.0 3.4 6.5 0.0 0.0 7.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.4 0.0 5.9 0.0 0.0 1.7 1.0 0.8 0.5 1.3 1.0 0.4 0.4 0.9 0.4 0.4 0.4 0.5 2.5 0.0 1.1 0.0 0.2 0.4 0.5 0.6 0.6 0.0 1.1 3.2 0.3 0.0 0.5 0.0 0.0 0.0 1.1 0.2 0.0 0.1 0.0 0.0 1.3 1.9 0.0 0.0 0.3 0.0 0.7 1.3 0.0 0.2 0.0 0.0 1.4 0.4 0.2 0.0 0.0 0.2 0.0 1.5 0.8 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 5.0 1.2 0.1 3.4 0.6 0.1 0.3 0.3 2.2 0.2 0.1 EML2 "ELP70, EMAP-2, EMAP2" ENSG00000125746 "EMAP like 2" O95834 19 45606994-45645602 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 153.1;Syncytiotrophoblasts: 101.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012757 Approved Approved Vesicles NA NA 180000 "Cluster 27: Non-specific - Gene expression" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 30: Epithelial cell lines - Translation" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles "HPA012757: AB_1848145" "unprognostic (1.10e-1)" "unprognostic (1.36e-1)" "unprognostic (1.61e-3)" "unprognostic (2.12e-1)" "unprognostic (1.81e-3)" "unprognostic (1.13e-1)" "unprognostic (1.69e-2)" "unprognostic (1.16e-1)" "unprognostic (1.85e-1)" "unprognostic (3.05e-3)" "unprognostic (3.72e-1)" "unprognostic (2.75e-3)" "unprognostic (1.77e-1)" "unprognostic (2.85e-2)" "unprognostic (9.44e-2)" "unprognostic (7.48e-2)" "unprognostic (7.03e-2)" 11.2 32.7 23.2 13.6 41.7 14.1 12.9 43.2 37.6 16.4 9.7 21.3 11.5 9.1 6.8 40.2 12.0 10.9 20.4 19.5 36.1 17.5 7.9 13.6 13.4 57.6 35.4 5.2 21.1 55.1 14.3 19.8 52.8 15.8 14.4 49.0 29.0 18.3 5.7 38.6 11.9 7.1 27.9 12.9 18.9 3.5 40.3 16.5 20.9 4.9 12.5 19.5 24.9 57.9 47.6 16.2 3.2 1.1 25.0 13.6 17.4 29.2 37.0 12.6 14.8 6.2 39.5 14.6 17.0 15.4 4.0 39.7 6.0 57.4 4.0 56.7 15.0 5.7 19.5 12.4 47.1 18.5 13.4 21.1 74.5 15.1 74.1 10.5 9.4 28.0 18.3 38.5 10.0 49.9 10.3 4.2 1.9 75.7 14.3 2.3 5.6 18.9 33.3 61.2 17.8 3.3 16.4 32.0 22.1 17.0 18.7 18.9 15.1 0.0 5.4 4.8 0.3 66.2 43.9 7.9 20.4 20.9 38.7 7.8 3.7 5.7 6.5 4.8 5.1 5.5 4.4 6.7 4.4 2.2 2.9 3.9 1.0 2.6 5.2 6.4 5.8 3.9 23.2 41.7 43.2 37.6 19.5 36.1 57.6 35.4 52.8 27.9 40.3 57.9 10.6 3.2 13.1 8.5 15.7 18.6 42.9 40.3 27.3 32.2 13.2 14.2 9.0 14.3 25.5 35.0 14.6 66.4 24.5 34.1 37.2 16.8 72.1 28.6 9.0 13.8 17.5 5.5 29.7 20.8 20.4 7.6 38.7 20.1 19.1 6.7 20.3 6.4 15.8 28.6 46.0 32.6 26.4 8.8 9.6 27.0 4.1 8.7 19.6 5.6 13.1 16.4 12.3 15.1 68.0 17.9 29.1 7.2 25.0 23.7 11.0 7.5 40.7 153.1 0.0 6.8 16.4 3.5 6.1 29.6 14.3 101.0 23.2 39.1 31.9 41.9 EML6 FLJ42562 ENSG00000214595 "EMAP like 6" Q6ZMW3 2 54723499-54972025 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.3;retina: 13.9" "Cell type enhanced" "Detected in many" "Astrocytes: 145.0;Excitatory neurons: 372.7;Inhibitory neurons: 265.1;Oligodendrocyte precursor cells: 95.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 10.9;SCLC-21H: 34.0;U-698: 35.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA062808, HPA068759" Uncertain Approved Vesicles,Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Mitochondria Vesicles "HPA062808: AB_2684872, HPA068759: AB_2686027" "unprognostic (1.06e-1)" "unprognostic (6.89e-4)" "unprognostic (7.83e-2)" "unprognostic (9.96e-2)" "unprognostic (6.24e-2)" "unprognostic (3.26e-4)" "unprognostic (5.27e-2)" "unprognostic (1.31e-1)" "unprognostic (2.26e-1)" "unprognostic (6.27e-2)" "unprognostic (6.85e-6)" "unprognostic (5.00e-1)" "unprognostic (5.81e-2)" "unprognostic (6.37e-3)" "unprognostic (1.43e-1)" "unprognostic (1.66e-2)" "unprognostic (5.13e-3)" 0.3 3.0 1.6 4.0 1.8 0.7 0.7 1.4 3.8 0.2 0.2 0.7 0.7 0.3 1.1 0.5 0.4 0.2 0.1 2.2 2.1 1.7 0.5 0.4 7.0 1.3 1.4 0.1 0.8 1.9 3.2 1.4 1.3 0.6 0.8 13.9 0.5 0.5 1.0 0.9 2.0 0.4 0.6 2.6 0.5 1.3 1.4 0.6 2.6 0.5 10.3 0.6 0.4 2.9 0.7 2.0 0.2 1.5 1.0 0.3 2.0 0.2 0.3 0.2 0.2 0.8 0.3 10.9 0.2 0.7 0.4 0.3 1.4 0.5 0.4 1.0 0.4 0.6 0.9 5.1 0.0 0.3 0.0 0.1 0.1 0.6 1.1 0.2 0.2 6.2 0.0 2.0 0.0 1.1 2.1 0.4 0.5 0.2 2.3 0.9 0.7 0.8 0.1 1.4 34.0 4.2 0.5 0.1 0.0 0.2 0.1 0.1 0.3 0.4 2.1 0.5 0.6 7.8 2.2 35.0 1.8 3.7 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.8 1.4 3.8 2.2 2.1 1.3 1.4 1.3 0.6 1.4 2.9 0.9 0.0 1.1 145.0 7.3 3.7 1.9 0.6 1.8 28.0 1.1 0.8 2.0 0.0 3.5 3.7 56.3 0.4 0.4 0.5 0.0 0.2 24.6 2.9 0.6 1.3 2.4 0.0 372.7 0.4 0.6 1.0 2.0 1.2 0.0 0.8 1.4 0.6 1.3 38.7 265.1 3.6 0.0 1.0 2.3 11.2 0.6 0.6 0.0 19.7 0.0 14.3 1.0 95.5 30.2 0.1 0.1 0.7 8.4 1.6 1.1 0.7 7.0 32.7 0.0 2.2 1.5 5.1 2.6 0.6 4.4 0.1 0.8 0.9 0.4 2.3 EMP1 "CL-20, TMP" ENSG00000134531 "Epithelial membrane protein 1" P54849 12 13196723-13219941 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2255.1;vagina: 819.5" "Cell type enhanced" "Detected in many" "Adipocytes: 835.5;Basal keratinocytes: 694.1;Endothelial cells: 662.2;Squamous epithelial cells: 888.5;Suprabasal keratinocytes: 687.6;Urothelial cells: 1193.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "myeloid DC: 3.4" "Lineage enriched" "Detected in single" 13 "dendritic cells: 3.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 1166.6;fHDF/TERT166: 861.7;HaCaT: 766.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 4.5;spinal cord: 16.0" HPA046912 Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA046912: " "unprognostic (1.40e-2)" "unprognostic (7.30e-2)" "unprognostic (8.01e-2)" "unprognostic (1.07e-2)" "unprognostic (1.69e-1)" "unprognostic (1.39e-1)" "unprognostic (8.41e-3)" "unprognostic (1.94e-1)" "unprognostic (2.67e-2)" "prognostic unfavorable (2.26e-8)" "prognostic unfavorable (7.46e-4)" "unprognostic (2.98e-1)" "unprognostic (4.84e-2)" "unprognostic (3.05e-2)" "unprognostic (3.45e-2)" "unprognostic (3.25e-1)" "prognostic unfavorable (9.69e-8)" 536.6 42.0 18.6 63.9 20.2 20.7 166.7 18.2 28.4 463.2 14.2 100.7 39.5 61.6 12.5 2255.1 84.8 205.8 121.8 17.7 46.5 93.9 35.1 177.9 11.4 29.5 22.9 21.8 86.8 20.6 29.9 76.9 27.2 39.6 56.4 5.5 377.8 20.3 27.0 150.9 41.8 149.2 25.1 26.2 48.5 9.2 20.8 28.4 133.5 35.6 165.4 205.7 819.5 22.1 373.5 19.4 9.1 1.9 563.2 1166.6 1.5 269.6 489.4 135.7 172.3 2.7 612.6 2.2 187.3 861.7 60.0 766.6 10.8 35.7 182.9 7.2 0.8 1.2 61.9 0.2 135.6 2.6 2.1 369.8 50.9 432.7 126.4 107.3 316.8 0.2 2.0 6.2 325.4 1.6 0.8 8.3 6.6 69.8 62.3 1.0 37.1 3.4 396.4 4.4 0.3 0.3 120.1 17.4 211.9 69.9 3.1 2.2 349.8 302.2 106.7 287.0 146.8 1.5 4.1 2.5 441.2 2.2 363.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 18.6 20.2 18.2 28.4 17.7 46.5 29.5 22.9 27.2 25.1 20.8 22.1 835.5 205.1 88.5 8.1 3.7 694.1 362.3 34.8 223.7 0.1 316.5 91.7 12.9 27.1 166.8 18.4 0.0 1.2 7.6 481.5 15.6 28.7 0.8 76.0 167.6 662.2 47.6 0.0 0.9 4.4 1.8 470.5 62.2 160.3 50.4 0.1 157.1 2.2 39.8 0.0 0.4 13.5 6.1 37.1 481.2 2.1 69.6 105.8 473.2 7.5 7.0 2.4 0.0 0.5 0.2 62.2 343.0 109.4 12.7 413.0 48.6 0.5 60.2 0.4 6.6 202.1 170.1 1.1 0.9 888.5 687.6 1.1 23.0 5.1 26.6 1193.8 EMP3 YMP ENSG00000142227 "Epithelial membrane protein 3" P54852 19 48321509-48330553 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 2037.4;Macrophages: 699.2;Melanocytes: 1117.1" "Cancer enhanced" "Detected in all" "melanoma: 195.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 1472.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062030 Approved "Vesicles,Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 41: Macrophages - Immune response" "Vesicles, Plasma membrane" "HPA062030: " "unprognostic (5.06e-3)" "unprognostic (4.41e-1)" "unprognostic (1.83e-1)" "unprognostic (9.28e-3)" "unprognostic (1.33e-2)" "unprognostic (4.83e-3)" "unprognostic (1.49e-2)" "unprognostic (1.02e-1)" "unprognostic (9.31e-2)" "unprognostic (4.72e-2)" "unprognostic (3.41e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (2.31e-7)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.16e-1)" "unprognostic (2.41e-1)" "unprognostic (2.90e-3)" 107.7 85.6 37.6 115.8 37.4 325.1 68.8 37.9 41.0 149.6 36.9 166.7 36.9 143.9 60.7 37.1 96.2 72.5 100.9 38.6 53.8 51.8 29.1 141.0 86.1 52.1 43.9 110.8 18.4 17.1 21.4 67.1 46.9 61.3 65.5 9.2 41.8 90.1 21.7 61.6 81.6 202.9 44.2 91.8 65.3 33.5 43.7 45.2 43.2 43.7 94.7 132.8 106.9 48.4 73.8 739.3 44.9 127.1 691.3 1081.5 1.2 490.7 898.0 627.6 560.7 73.5 265.0 6.9 107.5 1101.0 296.4 12.1 45.5 54.6 390.4 241.3 20.5 335.0 192.0 43.3 572.4 160.2 338.9 586.1 12.2 635.3 436.3 455.5 277.9 66.1 237.4 616.1 1019.5 10.1 25.1 1472.4 55.4 12.1 196.9 22.1 150.1 355.7 554.6 0.4 1.8 2.0 225.2 1.2 131.2 77.2 2.7 253.1 456.6 574.7 236.5 435.8 388.1 287.6 426.6 20.1 339.2 232.5 402.5 2401.3 980.4 1402.3 1324.0 1173.0 1117.1 570.1 1425.3 1327.0 688.7 467.9 818.8 948.4 1094.0 854.5 1148.4 516.9 1631.4 1971.4 37.6 37.4 37.9 41.0 38.6 53.8 52.1 43.9 46.9 44.2 43.7 48.4 66.5 0.0 4.5 5.5 338.0 278.0 75.4 161.0 48.3 2.3 14.7 22.9 5.4 21.5 21.8 33.1 0.0 14.9 375.9 1.5 5.9 72.0 6.5 18.9 255.1 118.6 6.0 94.8 0.2 11.2 26.0 371.3 23.0 15.1 257.0 8.5 128.2 7.2 589.0 0.0 0.3 4.1 42.7 458.8 2037.4 21.3 335.5 699.2 1117.1 6.5 444.5 64.6 565.4 0.0 0.7 114.3 28.2 217.0 334.9 285.5 1.7 9.3 14.6 5.0 105.2 193.0 278.7 16.2 6.7 10.6 189.9 20.2 441.4 29.1 4.9 44.4 ENTPD4 "KIAA0392, LALP70, LAP70, LYSAL1, NTPDase-4, UDPase" ENSG00000197217 "Ectonucleoside triphosphate diphosphohydrolase 4" Q9Y227 8 23385783-23457695 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017655 Supported Approved Vesicles NA NA 82000 "Cluster 2: Granulocytes - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" Vesicles "HPA017655: AB_1848181" "unprognostic (2.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (5.06e-2)" "unprognostic (7.86e-3)" "unprognostic (2.00e-2)" "unprognostic (2.99e-3)" "unprognostic (2.07e-2)" "unprognostic (8.74e-2)" "unprognostic (2.82e-1)" "unprognostic (1.20e-1)" "unprognostic (4.55e-2)" "unprognostic (1.39e-1)" "unprognostic (1.11e-1)" "unprognostic (6.62e-2)" "unprognostic (3.72e-2)" 16.3 11.5 8.6 24.2 10.5 30.5 14.8 11.1 16.2 17.0 8.1 19.8 18.1 16.8 17.3 12.6 13.7 14.6 21.2 10.8 12.3 12.2 13.7 20.0 29.3 13.1 9.2 13.5 21.4 27.2 18.3 17.2 12.8 16.8 20.3 32.7 22.0 13.4 15.2 12.4 26.2 16.5 7.6 25.4 20.3 19.9 12.5 14.5 14.7 15.9 29.8 16.7 16.6 11.6 20.8 28.7 34.0 23.5 29.0 36.8 35.0 33.1 30.4 21.3 33.2 40.3 26.4 35.5 22.9 32.8 32.9 24.5 15.8 29.0 40.3 8.6 11.5 18.4 18.1 14.2 23.7 9.8 34.8 22.8 34.7 28.4 29.9 51.9 31.2 26.7 13.2 30.6 36.4 9.3 14.8 11.9 20.1 26.2 10.2 14.3 34.6 10.8 27.0 24.1 27.2 26.6 12.0 17.0 23.7 67.0 12.9 13.6 38.6 39.1 38.3 43.7 24.1 24.7 11.5 45.5 51.3 11.5 39.4 17.0 5.7 13.4 7.4 8.6 8.8 8.7 7.3 8.1 7.5 6.5 9.2 7.3 14.4 4.8 7.0 6.8 6.3 6.9 8.6 10.5 11.1 16.2 10.8 12.3 13.1 9.2 12.8 7.6 12.5 11.6 15.9 19.2 34.5 10.7 25.8 6.5 12.0 17.6 8.6 32.1 11.4 8.6 24.6 7.2 27.3 14.7 14.6 16.1 33.4 25.1 0.0 15.6 8.6 13.6 21.6 15.8 17.3 10.3 31.4 16.9 16.9 16.9 23.9 23.9 17.7 18.9 12.1 11.5 12.3 47.1 37.4 19.7 20.3 14.2 15.5 19.2 7.2 18.2 12.4 19.7 19.4 15.2 18.6 23.1 23.1 21.8 13.3 8.6 46.9 18.9 18.8 5.0 15.0 35.9 13.1 14.3 14.6 21.5 22.8 9.5 5.5 20.2 21.3 11.7 12.4 18.9 ENTPD8 "NTPDase-8, UNQ2492" ENSG00000188833 "Ectonucleoside triphosphate diphosphohydrolase 8" Q5MY95 9 137434364-137441816 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 27.6;liver: 14.5" "Group enriched" "Detected in some" 5 "Distal enterocytes: 194.5;Intestinal goblet cells: 181.0;Paneth cells: 174.3;Proximal enterocytes: 167.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 5.0;OE19: 1.7;RPMI-8226: 5.3;T-47d: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA021509 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" Vesicles "HPA021509: AB_1848185" "unprognostic (3.85e-2)" "unprognostic (8.33e-2)" "unprognostic (2.11e-1)" "unprognostic (1.82e-1)" "unprognostic (1.30e-1)" "unprognostic (1.40e-1)" "unprognostic (6.46e-3)" "unprognostic (8.70e-2)" "unprognostic (3.87e-2)" "unprognostic (8.48e-2)" "unprognostic (1.69e-1)" "unprognostic (2.34e-2)" "unprognostic (1.08e-5)" "prognostic favorable (7.17e-4)" "unprognostic (2.17e-1)" "unprognostic (1.15e-1)" "unprognostic (1.78e-1)" 0.0 0.0 0.0 1.4 0.0 0.4 0.4 0.2 0.2 0.6 0.0 21.3 27.6 0.1 0.0 0.3 0.7 3.7 0.0 0.0 0.0 3.1 14.5 0.1 0.1 0.2 0.1 0.1 3.1 0.1 5.1 0.1 0.0 0.4 11.2 0.0 6.3 0.2 0.0 0.1 27.2 0.1 0.0 0.2 8.9 0.5 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.1 5.0 0.0 0.3 0.0 0.4 0.1 0.0 0.0 0.0 1.0 0.1 0.0 0.4 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 1.7 0.2 0.0 0.0 5.3 0.7 0.0 0.2 0.5 0.1 0.0 0.1 0.4 2.8 0.1 0.0 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.0 1.7 1.5 0.4 11.5 0.3 20.2 0.0 0.0 0.1 194.5 0.0 1.3 0.0 3.0 0.4 0.1 3.6 0.0 0.0 7.5 0.2 0.1 31.6 4.7 0.0 0.1 0.4 10.1 0.1 0.0 0.0 181.0 8.2 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 174.3 0.0 0.2 0.6 167.3 5.9 1.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.3 0.3 0.1 15.6 1.7 EPC1 Epl1 ENSG00000120616 "Enhancer of polycomb homolog 1" Q9H2F5 10 32267751-32378798 "Predicted intracellular proteins" "Growth regulation, Transcription, Transcription regulation" "Activator, Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 149.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028931 Approved Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" "HPA028931: " "unprognostic (6.94e-2)" "unprognostic (3.03e-2)" "unprognostic (9.93e-2)" "unprognostic (9.43e-2)" "unprognostic (5.73e-2)" "prognostic favorable (6.40e-4)" "unprognostic (1.80e-2)" "unprognostic (3.83e-3)" "unprognostic (7.43e-2)" "unprognostic (5.55e-2)" "prognostic favorable (6.02e-4)" "unprognostic (4.40e-2)" "unprognostic (1.59e-3)" "unprognostic (1.03e-1)" "unprognostic (1.29e-1)" "unprognostic (2.08e-1)" "unprognostic (1.18e-3)" 14.4 9.6 12.5 13.9 13.7 149.7 19.4 21.2 14.5 17.5 12.0 15.9 11.5 20.6 15.8 11.1 14.8 12.8 11.9 12.4 12.0 11.9 13.8 14.7 21.5 12.4 12.7 23.4 14.4 14.6 10.3 11.7 13.0 15.0 16.1 19.3 15.0 10.3 22.7 13.8 12.9 16.8 12.5 18.6 13.9 14.4 12.4 31.9 16.8 23.4 17.6 15.2 14.1 16.2 12.0 9.6 21.4 17.9 10.6 14.1 12.4 12.2 6.9 15.6 12.8 10.7 15.1 21.8 8.0 13.6 8.2 12.1 12.1 10.4 10.8 15.9 19.4 18.0 13.5 19.2 11.4 14.1 24.7 12.9 15.8 9.3 7.3 13.9 12.8 18.3 18.8 27.7 12.6 12.9 21.5 10.1 5.3 11.4 8.4 27.7 18.3 11.2 12.1 10.9 18.7 17.8 11.4 8.3 20.1 11.8 8.6 18.7 11.6 9.3 22.7 7.8 10.6 11.3 12.2 35.6 10.0 21.1 8.4 65.8 15.3 36.3 18.9 10.2 16.0 27.4 16.9 15.0 9.1 30.9 17.5 16.1 46.8 13.4 13.2 27.4 21.1 7.7 12.5 13.7 21.2 14.5 12.4 12.0 12.4 12.7 13.0 12.5 12.4 16.2 103.8 41.7 50.9 133.2 166.8 28.6 85.0 54.0 78.6 101.4 69.6 84.3 32.4 52.9 49.2 40.5 68.8 34.9 182.6 55.5 9.8 51.5 11.8 54.1 86.7 70.1 98.6 74.9 108.0 43.6 40.7 71.8 58.1 65.8 85.4 74.9 58.5 35.8 35.2 114.4 106.7 63.9 50.8 55.7 46.8 13.1 94.8 84.4 40.9 134.0 75.4 57.3 148.3 161.9 131.8 49.9 52.3 68.1 139.4 71.6 50.4 20.5 44.1 85.8 98.6 134.9 82.5 77.8 58.3 62.9 24.9 46.1 175.3 56.5 51.0 72.4 EPGN "ALGV3072, EPG, PRO9904" ENSG00000182585 "Epithelial mitogen" Q6UW88 4 74308470-74316789 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "esophagus: 49.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.0;Basal prostatic cells: 7.3;Basal squamous epithelial cells: 25.6;Urothelial cells: 5.1" "Cancer enriched" "Detected in some" 5 "head and neck cancer: 7.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTCEpi: 157.9;U-2197: 74.8" "Not detected" "Not detected" HPA014420 Approved Nucleoplasm,Vesicles,Cytosol "Secreted in other tissues" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" Vesicles "HPA014420: AB_10601551" "unprognostic (7.51e-2)" "unprognostic (8.08e-3)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "unprognostic (1.77e-1)" "unprognostic (2.38e-4)" "unprognostic (2.20e-1)" "unprognostic (2.01e-1)" "unprognostic (1.23e-2)" "unprognostic (1.27e-1)" "unprognostic (4.06e-4)" "unprognostic (3.84e-1)" "unprognostic (7.89e-2)" "prognostic unfavorable (2.40e-4)" 1.6 0.1 0.2 1.6 0.1 0.3 1.4 0.4 0.6 5.2 0.1 0.1 0.1 0.0 1.1 49.0 1.5 0.1 0.8 0.2 0.1 0.1 0.2 0.5 0.1 0.2 0.3 0.1 0.1 2.2 0.1 0.5 0.1 0.2 0.0 0.2 3.6 3.1 0.1 3.5 0.1 0.0 0.1 0.3 0.0 1.1 0.1 0.9 0.0 0.0 3.4 1.3 9.6 0.4 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.2 0.0 0.0 0.4 0.0 0.8 0.0 0.1 1.8 0.2 3.6 0.0 2.8 0.0 0.0 0.0 0.5 20.2 0.0 0.2 0.0 0.7 0.0 157.9 2.9 11.7 0.0 0.0 0.1 0.6 0.0 0.0 1.0 0.0 0.0 0.3 0.0 3.6 0.4 0.0 0.0 0.3 0.3 0.1 0.0 8.3 3.3 0.0 0.0 0.5 0.0 0.2 0.4 0.1 74.8 0.2 0.0 0.0 0.1 0.7 0.1 0.2 0.7 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.0 0.3 0.3 0.1 0.7 0.3 0.1 0.2 0.1 0.1 0.2 0.1 0.4 0.6 0.2 0.1 0.2 0.3 0.1 0.1 0.1 0.4 0.0 0.0 1.5 0.0 0.0 6.0 7.3 0.9 25.6 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 3.1 0.0 0.1 1.8 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 3.0 1.6 0.1 0.2 0.0 0.0 5.1 EPHX4 "ABHD7, EH4, EPHXRP, FLJ90341" ENSG00000172031 "Epoxide hydrolase 4" Q8IUS5 1 92029985-92063538 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.9;choroid plexus: 5.7" "Group enriched" "Detected in many" 5 "Excitatory neurons: 55.3;Inhibitory neurons: 32.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 12.1" "Lineage enriched" "Detected in single" 21 "T-cells: 12.1" "Cell line enhanced" "Detected in some" "A-431: 15.4;CAPAN-2: 13.0;EFO-21: 25.9;RPTEC TERT1: 36.1;U-251 MG: 10.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA035067 Uncertain Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA035067: AB_10601465" "unprognostic (1.27e-1)" "unprognostic (4.17e-2)" "unprognostic (6.76e-3)" "unprognostic (6.10e-8)" "prognostic unfavorable (9.43e-4)" "unprognostic (5.36e-3)" "unprognostic (2.72e-4)" "unprognostic (4.85e-2)" "unprognostic (9.44e-3)" "unprognostic (7.93e-2)" "prognostic unfavorable (2.00e-4)" "unprognostic (2.53e-1)" "unprognostic (6.36e-6)" "unprognostic (6.93e-3)" "unprognostic (1.02e-1)" "unprognostic (1.67e-1)" "unprognostic (1.25e-1)" 0.5 0.5 4.0 0.5 9.2 0.0 1.4 1.9 10.9 0.9 5.7 0.6 0.6 0.6 0.5 0.8 0.4 0.4 0.5 6.9 2.3 0.4 0.0 0.6 0.2 3.1 2.3 0.1 0.0 0.4 1.1 0.8 3.1 0.9 0.5 2.1 0.2 1.8 0.1 0.5 0.4 1.1 1.8 0.0 0.3 1.2 2.8 0.0 1.8 0.1 0.2 0.7 0.2 5.5 15.4 0.5 2.9 0.0 0.0 0.0 0.7 0.3 5.5 0.5 0.3 0.0 13.0 0.0 25.9 0.0 3.9 0.2 0.5 1.2 0.5 0.0 8.0 0.0 0.1 0.0 0.2 1.1 0.0 0.9 0.7 0.0 0.0 9.4 4.5 0.0 0.1 0.0 0.4 0.9 2.2 0.6 2.8 0.0 5.2 0.5 0.3 0.0 36.1 3.0 1.8 2.2 9.1 0.0 2.9 0.2 0.0 2.2 0.2 0.0 0.1 0.0 10.9 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 12.1 0.0 2.0 0.1 1.4 3.0 0.0 0.0 0.3 2.8 0.0 0.5 0.0 0.0 0.0 1.5 4.0 9.2 1.9 10.9 6.9 2.3 3.1 2.3 3.1 1.8 2.8 5.5 2.0 0.0 0.0 4.9 0.0 0.1 0.1 2.0 0.0 2.0 6.7 4.6 1.0 0.0 1.5 0.0 2.1 0.4 3.2 0.1 0.0 0.4 1.7 1.0 0.1 6.2 0.0 0.0 55.3 0.9 0.7 0.3 0.0 1.3 0.0 0.3 0.4 0.0 0.2 1.7 32.5 0.0 0.0 0.0 0.4 0.1 0.0 0.2 3.6 4.7 0.1 8.6 0.0 5.5 2.7 5.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 1.6 0.0 0.1 0.8 6.0 0.7 0.1 0.4 0.0 1.1 0.2 0.3 0.3 EPN1 ENSG00000063245 "Epsin 1" Q9Y6I3 19 55675226-55709858 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 387.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 263.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009729, HPA061136, HPA071503" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB009729: AB_2277865, HPA061136: AB_2684436, HPA071503: " "unprognostic (6.93e-2)" "unprognostic (2.47e-1)" "unprognostic (5.30e-2)" "unprognostic (1.32e-1)" "unprognostic (7.94e-2)" "unprognostic (8.76e-2)" "unprognostic (1.23e-2)" "unprognostic (7.23e-3)" "unprognostic (1.18e-1)" "unprognostic (1.28e-1)" "unprognostic (6.16e-2)" "unprognostic (4.63e-2)" "unprognostic (1.05e-2)" "unprognostic (3.86e-3)" "unprognostic (1.57e-1)" "unprognostic (2.78e-3)" "unprognostic (7.92e-3)" 57.1 75.3 63.1 27.3 61.2 22.1 53.0 30.3 82.2 51.1 14.8 73.1 88.7 47.8 9.2 80.5 48.7 14.3 148.6 65.2 31.5 85.2 137.1 50.5 19.3 37.8 38.5 76.2 104.3 22.3 51.1 17.4 31.1 64.8 16.2 8.9 50.9 20.0 156.1 71.0 80.4 11.0 27.9 72.8 152.6 80.8 40.0 11.6 49.0 35.3 11.2 50.1 54.5 47.1 95.5 128.8 31.5 64.8 35.6 33.8 64.6 69.3 39.0 48.2 48.0 54.1 58.7 58.1 46.1 55.6 42.5 71.5 27.7 52.9 17.4 20.4 263.2 42.8 67.4 65.3 48.9 27.8 39.3 43.9 45.6 41.7 30.1 34.7 46.4 40.7 64.7 48.0 32.2 53.6 44.4 45.2 72.3 71.4 179.6 29.5 42.8 103.2 36.8 55.3 45.2 109.9 64.1 68.8 48.0 21.7 51.6 95.7 78.4 133.0 63.8 48.4 101.3 52.2 50.9 41.7 97.9 55.0 67.5 1.4 1.8 2.3 0.6 2.2 0.4 1.0 0.6 0.6 1.1 0.8 0.6 0.6 2.1 0.3 3.6 1.7 0.9 1.5 63.1 61.2 30.3 82.2 65.2 31.5 37.8 38.5 31.1 27.9 40.0 47.1 62.6 3.2 20.4 9.8 44.2 31.4 29.0 25.9 44.3 33.3 32.7 25.8 15.5 55.8 17.9 44.1 66.7 46.1 28.1 227.7 119.3 57.1 63.2 39.5 37.5 46.1 45.0 35.3 7.8 88.5 80.8 37.2 145.2 45.9 10.8 87.0 83.9 106.1 62.9 28.6 7.8 115.6 22.4 136.5 21.4 169.4 47.5 55.4 23.2 6.5 40.8 33.6 28.8 4.5 8.9 106.5 167.7 53.0 57.7 37.6 387.2 81.8 20.9 41.3 13.1 41.2 34.6 50.2 62.7 46.6 27.4 52.3 26.3 48.2 132.5 39.2 EPN2 "EHB21, KIAA1065" ENSG00000072134 "Epsin 2" O95208 17 19215615-19336715 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 6 "Oligodendrocyte precursor cells: 868.6;Oligodendrocytes: 258.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 10.9;eosinophil: 29.0;neutrophil: 9.0" "Lineage enriched" "Detected in many" 8 "granulocytes: 29.0" "Cell line enhanced" "Detected in many" "SuSa: 127.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049809, HPA053360" Approved Supported Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Vesicles "HPA049809: AB_2680893, HPA053360: AB_2682126" "unprognostic (1.38e-2)" "unprognostic (2.54e-2)" "unprognostic (2.58e-2)" "unprognostic (2.09e-1)" "unprognostic (1.94e-1)" "unprognostic (8.12e-3)" "unprognostic (6.73e-3)" "unprognostic (1.43e-1)" "unprognostic (8.89e-2)" "unprognostic (4.58e-3)" "unprognostic (3.42e-2)" "unprognostic (1.57e-1)" "prognostic favorable (9.13e-5)" "unprognostic (1.32e-1)" "unprognostic (9.40e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (8.15e-5)" 20.5 13.9 62.1 9.7 64.9 11.5 16.7 50.4 62.8 36.3 32.7 28.3 9.6 29.5 11.5 40.3 26.6 14.6 32.5 62.6 56.2 21.3 9.3 18.6 6.5 61.6 63.6 22.5 14.6 15.3 18.1 21.6 57.5 23.6 9.5 19.1 17.9 23.4 22.4 50.1 13.3 22.5 46.6 14.3 15.9 19.7 63.6 4.7 17.8 17.0 8.4 27.0 33.8 91.6 31.3 30.4 43.9 19.2 22.8 36.3 34.5 29.4 18.9 17.9 15.3 20.2 9.2 4.9 28.2 29.5 16.8 29.0 19.8 22.1 21.9 23.6 21.2 3.2 20.3 9.2 23.7 1.4 13.1 20.5 19.5 28.3 22.7 23.2 38.8 6.6 8.6 3.9 15.8 22.5 1.3 2.1 11.1 41.3 19.8 7.1 18.8 8.1 21.0 8.6 13.0 28.8 20.9 13.9 14.7 127.9 21.0 4.0 35.6 19.7 22.3 30.9 12.9 6.7 4.3 3.9 54.0 0.5 31.1 10.9 1.3 29.0 1.6 0.8 1.2 3.0 1.1 1.3 0.5 3.4 1.3 1.2 9.0 0.7 1.0 0.6 1.0 0.7 62.1 64.9 50.4 62.8 62.6 56.2 61.6 63.6 57.5 46.6 63.6 91.6 60.0 54.5 29.3 74.4 13.7 24.1 36.6 21.2 43.9 68.3 32.8 33.4 44.5 25.8 25.0 38.6 47.9 27.6 3.3 7.2 27.4 22.5 36.8 69.2 35.0 42.5 6.0 13.5 51.3 8.4 39.8 36.1 15.8 40.6 14.0 37.3 15.0 10.4 8.4 35.3 45.0 16.8 10.2 5.1 6.2 72.7 46.6 5.9 5.4 54.4 1.6 38.3 2.1 868.6 258.3 23.3 14.9 39.5 14.4 32.0 7.0 14.2 43.2 82.3 26.3 50.5 63.7 45.8 38.3 63.9 48.9 21.9 7.4 35.0 7.8 40.1 EPN3 "FLJ20778, MGC129899" ENSG00000049283 "Epsin 3" Q9H201 17 50532682-50543750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 35.9;stomach 1: 37.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 77.9;Distal enterocytes: 27.6;Gastric mucus-secreting cells: 44.9;Intestinal goblet cells: 24.9;Squamous epithelial cells: 30.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 28.6;HBEC3-KT: 40.3;MCF7: 66.4;OE19: 62.8;RT4: 50.2;SK-BR-3: 25.8;T-47d: 57.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA055546, HPA063224" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles Nucleoplasm "HPA055546: AB_2682844, HPA063224: AB_2684964" "unprognostic (1.91e-2)" "unprognostic (1.99e-2)" "unprognostic (2.41e-1)" "unprognostic (2.91e-2)" "unprognostic (1.25e-3)" "unprognostic (2.06e-1)" "unprognostic (5.70e-3)" "unprognostic (7.62e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-1)" "unprognostic (6.66e-3)" "unprognostic (1.00e-2)" "prognostic favorable (1.53e-5)" "unprognostic (1.45e-1)" "unprognostic (1.16e-1)" "unprognostic (4.90e-1)" "unprognostic (3.52e-3)" 0.2 8.9 2.3 0.8 1.3 0.6 2.3 6.4 6.0 6.5 1.2 7.1 6.8 0.4 3.2 35.9 7.5 5.9 7.1 0.7 2.1 6.0 0.1 0.3 0.0 11.5 5.4 13.5 23.0 21.2 0.8 4.2 13.6 9.9 4.4 0.2 11.1 5.6 0.1 30.5 3.2 0.1 0.5 0.0 37.3 2.8 13.4 3.2 1.1 0.0 3.7 5.5 12.9 1.8 20.5 0.3 0.0 0.2 0.0 0.0 5.3 0.0 0.0 0.0 0.0 14.7 12.1 0.0 0.2 0.0 0.1 28.6 0.0 40.3 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.1 0.2 0.1 21.8 0.1 3.0 0.0 0.0 0.1 0.0 0.0 0.0 66.4 0.3 0.0 0.0 62.8 0.4 0.0 0.0 0.1 0.2 50.2 0.4 0.0 0.0 25.8 0.0 0.4 57.4 0.2 1.5 0.3 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 1.3 6.4 6.0 0.7 2.1 11.5 5.4 13.6 0.5 13.4 1.8 0.2 0.0 0.0 0.0 0.4 2.3 4.4 4.1 10.8 2.9 6.5 3.4 5.4 8.6 8.3 18.4 0.0 77.9 0.0 27.6 5.9 9.2 1.0 3.8 0.6 0.4 3.6 0.0 1.0 11.5 7.4 0.8 44.9 5.5 0.0 3.1 0.0 0.0 5.9 0.0 1.7 24.9 2.0 0.0 0.0 2.1 2.8 0.5 0.0 1.0 0.6 0.6 0.0 0.0 0.0 3.4 10.3 0.0 1.3 4.9 2.1 0.3 4.3 0.9 0.0 0.0 0.8 0.0 0.5 30.0 5.5 10.7 0.2 12.4 19.3 7.8 EPS15 "AF-1P, MLLT5" ENSG00000085832 "Epidermal growth factor receptor pathway substrate 15" P42566 1 51354263-51519266 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Host-virus interaction, Protein transport, Transport" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 314.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008451, CAB010164, HPA061431" Approved Enhanced Vesicles,Cytosol "Intracellular and membrane" NA NA 65000 "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Vesicles, Cytosol" "CAB010164: AB_631445, HPA008451: AB_1848221, HPA061431: AB_2732662" "unprognostic (1.45e-2)" "prognostic unfavorable (6.44e-4)" "unprognostic (1.05e-2)" "unprognostic (7.72e-3)" "unprognostic (3.99e-1)" "unprognostic (1.42e-1)" "unprognostic (4.96e-3)" "unprognostic (9.26e-2)" "unprognostic (4.13e-2)" "unprognostic (5.80e-2)" "unprognostic (1.17e-1)" "unprognostic (1.41e-1)" "unprognostic (5.36e-2)" "unprognostic (8.73e-3)" "unprognostic (2.13e-1)" "unprognostic (1.21e-1)" "unprognostic (1.24e-1)" 31.9 35.1 40.3 25.5 48.2 20.7 25.6 38.8 55.7 23.9 25.7 19.1 15.8 22.8 17.6 21.0 18.3 26.1 26.5 43.9 39.1 24.5 26.4 26.9 46.0 38.6 44.1 28.8 14.7 29.0 15.5 31.5 40.7 26.7 20.5 23.4 16.7 20.9 47.6 24.2 17.7 24.3 40.1 34.1 21.3 46.9 45.0 27.6 25.3 40.5 45.6 22.8 20.9 57.2 35.4 10.4 22.0 20.8 49.6 49.2 54.5 24.2 37.9 19.4 28.4 14.4 19.2 71.8 24.3 38.1 39.5 32.7 28.7 23.1 29.1 81.8 18.0 64.1 16.9 17.1 46.7 36.9 56.4 40.3 21.0 34.0 45.7 33.5 36.5 25.2 40.4 31.7 29.8 17.5 29.9 19.8 30.2 24.6 16.7 24.1 33.3 15.9 25.5 43.2 15.0 20.9 28.8 50.4 42.1 60.2 20.5 25.7 51.1 18.0 19.1 36.3 20.5 37.6 41.0 47.6 26.6 41.0 16.1 18.8 10.4 12.1 9.4 10.7 14.2 15.6 11.2 14.9 10.8 9.0 6.6 9.6 7.8 10.8 13.0 7.1 19.0 8.7 40.3 48.2 38.8 55.7 43.9 39.1 38.6 44.1 40.7 40.1 45.0 57.2 51.5 35.3 41.0 142.4 78.3 43.0 32.1 16.4 30.1 18.1 28.2 15.6 59.8 24.3 22.7 44.1 31.3 22.8 65.0 28.5 19.6 15.2 27.0 22.1 50.1 43.3 28.8 81.0 77.1 19.0 18.9 52.5 41.3 35.6 24.6 36.0 61.4 37.7 83.4 28.6 60.6 30.7 12.2 80.9 61.9 61.7 65.9 67.0 103.2 110.5 57.6 38.4 27.8 29.7 314.1 23.3 19.8 48.2 78.4 62.1 20.7 28.1 31.9 26.6 39.5 45.1 38.0 74.4 44.5 33.8 51.0 28.5 74.3 28.5 21.4 50.8 EPS15L1 eps15R ENSG00000127527 "Epidermal growth factor receptor pathway substrate 15 like 1" Q9UBC2 19 16355239-16472085 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019237, HPA055309" Approved Approved Vesicles NA NA 110000 "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA019237: AB_1848223, HPA055309: AB_2682780" "unprognostic (3.06e-2)" "unprognostic (3.33e-3)" "unprognostic (2.19e-1)" "unprognostic (6.45e-3)" "unprognostic (1.35e-1)" "unprognostic (8.64e-2)" "unprognostic (2.58e-3)" "unprognostic (5.12e-2)" "unprognostic (1.07e-3)" "unprognostic (7.54e-2)" "unprognostic (5.21e-2)" "unprognostic (1.81e-2)" "prognostic favorable (8.10e-5)" "unprognostic (2.47e-1)" "unprognostic (9.59e-2)" "unprognostic (2.14e-1)" "unprognostic (3.32e-1)" 15.3 17.6 33.4 11.8 32.4 23.6 14.2 39.6 40.5 22.4 21.5 17.0 8.3 18.1 5.9 25.2 18.7 9.6 42.4 35.6 29.1 20.5 17.9 14.6 13.9 29.3 33.4 19.1 15.5 18.2 22.6 13.9 30.8 19.5 9.2 14.0 14.9 12.9 67.6 23.3 14.3 14.1 23.5 19.8 16.8 22.9 41.0 11.8 17.5 25.7 13.0 17.6 19.7 27.6 27.3 12.8 25.8 20.4 27.4 21.1 40.3 17.8 14.9 28.8 25.1 15.3 18.2 29.2 30.4 26.1 22.8 26.6 36.3 20.8 25.1 15.8 36.8 24.7 17.4 29.8 27.7 22.8 26.7 17.6 21.1 31.9 22.3 28.6 23.6 24.5 20.1 31.2 24.5 53.9 25.4 32.5 17.7 36.4 41.7 32.2 12.5 24.3 19.8 27.9 23.3 15.3 18.6 17.5 17.7 19.2 58.3 21.3 24.5 18.2 12.2 57.3 31.4 8.8 19.4 27.7 20.2 31.9 24.5 53.5 11.9 35.9 11.1 12.0 10.5 20.8 9.8 12.0 9.2 19.3 10.1 7.8 56.2 19.1 14.4 8.6 10.7 9.0 33.4 32.4 39.6 40.5 35.6 29.1 29.3 33.4 30.8 23.5 41.0 27.6 10.8 9.6 9.8 62.3 22.1 16.6 14.0 12.0 12.0 30.7 9.5 8.1 20.4 7.2 10.9 9.2 50.1 21.7 30.8 11.7 9.8 11.0 74.9 10.7 13.0 11.8 11.3 13.9 49.7 5.7 19.7 16.0 16.3 12.1 12.0 22.3 11.0 8.2 20.0 11.8 63.4 10.7 24.4 10.6 14.8 15.1 18.6 13.8 3.6 30.9 13.0 9.9 34.0 36.2 35.6 9.3 9.1 20.3 18.7 15.0 9.0 12.9 14.7 25.9 19.7 20.3 13.9 18.5 16.7 22.3 24.4 10.9 15.8 18.7 9.8 22.2 EPS8L3 "FLJ21522, MGC16817" ENSG00000198758 "EPS8 like 3" Q8TE67 1 109750080-109764027 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "gallbladder: 35.7;intestine: 142.1;stomach 1: 50.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 254.4;Gastric mucus-secreting cells: 80.5;Intestinal goblet cells: 103.4;Late spermatids: 144.6;Paneth cells: 257.8;Proximal enterocytes: 285.3;Undifferentiated cells: 112.6" "Group enriched" "Detected in many" 6 "colorectal cancer: 52.5;pancreatic cancer: 29.7;stomach cancer: 26.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 15.6;CAPAN-2: 14.4;Hep G2: 36.2;OE19: 67.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA030998 Approved Approved Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA030998: AB_2673691" "unprognostic (1.73e-3)" "unprognostic (1.80e-1)" "unprognostic (1.24e-1)" "unprognostic (2.76e-2)" "unprognostic (2.48e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (4.13e-5)" "unprognostic (5.55e-3)" "unprognostic (3.71e-2)" "unprognostic (2.09e-1)" "unprognostic (2.33e-1)" "prognostic unfavorable (2.52e-5)" "unprognostic (5.87e-3)" "unprognostic (3.89e-1)" "prognostic favorable (1.82e-4)" 0.0 0.0 0.1 10.8 0.0 0.0 0.2 0.0 0.0 1.3 0.0 77.1 141.8 0.2 0.9 0.1 0.1 35.7 0.1 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.1 77.1 0.0 0.0 0.2 0.0 0.0 142.1 2.9 0.0 0.0 50.7 2.5 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 15.6 14.4 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 67.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 14.3 0.3 0.0 0.0 0.0 0.0 254.4 0.0 11.6 28.0 0.7 0.1 0.3 51.4 0.0 0.0 23.9 0.0 0.0 80.5 1.0 4.5 0.0 0.0 0.2 0.0 0.0 0.0 103.4 0.0 0.0 0.0 144.6 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.5 257.8 0.4 0.3 0.0 285.3 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.4 0.6 112.6 1.8 ERC1 "CAST2, ELKS, KIAA1081, MGC12974, RAB6IP2" ENSG00000082805 "ELKS/RAB6-interacting/CAST family member 1" Q8IUD2 12 990509-1495933 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 292.3;Horizontal cells: 185.1;Inhibitory neurons: 487.0;Microglial cells: 213.6;Oligodendrocyte precursor cells: 230.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019513, HPA019523, HPA024130" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Vesicles, Plasma membrane" "HPA019513: AB_1856012, HPA019523: AB_1856013, HPA024130: AB_1856014" "unprognostic (2.41e-1)" "unprognostic (4.00e-2)" "unprognostic (2.14e-1)" "unprognostic (5.70e-2)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "unprognostic (5.50e-2)" "unprognostic (8.49e-2)" "unprognostic (2.53e-1)" "unprognostic (3.26e-2)" "unprognostic (1.04e-1)" "unprognostic (6.79e-2)" "unprognostic (3.75e-3)" "unprognostic (4.19e-2)" "unprognostic (3.01e-1)" "unprognostic (7.37e-2)" "prognostic unfavorable (7.01e-4)" 10.4 9.7 12.2 6.8 14.4 7.3 8.0 38.1 12.8 8.9 8.0 11.8 3.5 9.0 4.8 11.8 8.2 7.5 13.9 15.2 18.5 9.2 6.5 7.3 4.8 13.7 14.8 10.5 7.6 15.4 8.1 11.8 13.7 9.5 6.2 7.0 8.4 12.1 9.4 9.4 5.8 12.9 11.9 5.8 7.2 7.5 17.7 7.9 13.4 9.0 5.3 13.4 9.0 12.6 8.2 20.1 10.3 7.1 27.8 22.2 14.2 25.0 20.0 17.0 15.3 17.7 10.0 12.5 3.4 33.2 16.8 13.3 22.1 19.7 23.1 25.9 11.6 30.3 20.1 9.3 21.1 16.1 6.9 18.7 17.0 30.0 55.6 20.7 22.3 7.9 9.6 23.9 12.9 9.2 5.2 3.5 16.8 8.1 9.7 9.9 38.9 3.8 16.9 14.2 6.3 12.3 38.8 9.3 13.9 37.6 9.3 7.0 39.6 29.6 29.0 21.6 24.0 6.4 13.1 18.1 19.2 9.4 12.9 1.5 3.1 2.3 1.7 1.2 2.4 12.7 2.7 2.7 2.7 5.6 3.8 2.7 2.4 1.4 4.8 3.4 2.8 0.7 12.2 14.4 38.1 12.8 15.2 18.5 13.7 14.8 13.7 11.9 17.7 12.6 36.9 25.6 25.1 155.4 21.2 21.0 25.6 9.4 29.0 39.2 13.2 14.1 56.4 17.2 17.4 20.2 47.9 34.1 12.6 12.7 1.9 20.3 34.3 31.2 43.4 34.6 30.0 7.6 292.3 13.4 18.0 32.3 23.9 53.9 14.5 59.2 24.3 17.3 12.4 185.1 487.0 11.9 2.0 12.6 16.5 35.2 24.8 17.0 14.2 213.6 18.4 34.8 6.2 230.7 171.1 18.5 10.3 30.9 39.1 30.8 6.1 4.1 13.2 33.4 19.7 35.5 33.1 18.5 28.8 33.8 27.4 78.7 15.8 18.7 10.3 29.4 EREG ER ENSG00000124882 Epiregulin O14944 4 74365145-74388749 "Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "bone marrow: 129.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 179.1;Kupffer cells: 133.9;Langerhans cells: 171.1;Macrophages: 570.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 270.0;CAPAN-2: 76.7;hTEC/SVTERT24-B: 83.7;U-2197: 181.4;U-87 MG: 307.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA054373 Approved Vesicles "Secreted to blood" NA NA 46000 "Cluster 67: Neutrophils - Humoral immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" Vesicles "HPA054373: " "unprognostic (1.26e-2)" "prognostic unfavorable (1.67e-7)" "unprognostic (4.56e-3)" "unprognostic (3.94e-2)" "unprognostic (2.24e-3)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "prognostic unfavorable (1.45e-5)" "unprognostic (1.07e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (6.57e-5)" "unprognostic (2.94e-1)" "unprognostic (1.70e-6)" "unprognostic (2.42e-2)" "unprognostic (1.13e-2)" "unprognostic (6.59e-3)" "unprognostic (3.16e-3)" 4.5 0.0 0.3 10.3 0.3 129.0 2.5 0.2 0.5 1.9 0.2 2.0 0.2 0.2 0.2 12.6 0.8 5.7 0.7 0.3 0.1 0.1 0.2 2.7 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.6 0.4 0.1 3.4 0.1 1.3 0.0 0.2 9.3 1.6 3.0 0.0 0.5 0.2 0.1 0.6 0.1 0.1 0.0 1.0 4.9 4.0 0.3 1.4 41.1 0.0 0.0 3.8 6.6 0.1 9.2 270.0 2.6 1.6 32.5 76.7 0.0 44.1 0.0 20.1 2.4 0.0 59.3 2.7 0.0 0.0 1.2 1.6 1.2 1.1 0.1 0.1 3.9 20.2 83.7 43.5 0.0 0.0 0.0 0.1 0.5 0.2 0.4 0.1 0.1 0.1 0.2 0.6 0.1 0.0 0.1 0.6 1.6 0.0 0.0 27.0 0.2 0.0 0.0 0.1 0.0 0.0 1.6 0.6 181.4 0.0 0.0 0.0 0.2 307.0 0.0 0.2 0.4 0.2 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.5 0.3 0.1 0.2 0.1 0.4 0.0 0.6 0.3 4.9 6.4 7.2 0.0 5.7 5.4 5.6 179.1 4.0 0.0 24.4 2.3 18.2 5.7 82.4 0.0 0.0 0.4 2.2 56.3 0.0 1.8 3.7 2.4 0.7 2.5 3.6 17.0 0.1 0.2 0.7 4.4 0.5 3.9 7.0 0.1 0.4 1.9 26.8 0.0 1.8 38.2 16.2 133.9 171.1 1.0 0.3 570.7 7.2 0.0 23.2 0.0 0.0 0.0 0.0 0.8 27.1 0.0 11.7 2.5 32.4 0.2 41.9 0.0 0.0 2.5 3.1 0.5 0.3 3.8 9.2 0.7 3.3 0.2 33.1 7.4 ERGIC1 "ERGIC-32, ERGIC32, KIAA1181, NET24" ENSG00000113719 "Endoplasmic reticulum-golgi intermediate compartment 1" Q969X5 5 172834251-172952683 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 247.8;Intestinal goblet cells: 202.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018666, HPA018900" Enhanced Enhanced Nucleoplasm,Vesicles NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Vesicles" "HPA018666: AB_1848241, HPA018900: AB_1848242" "unprognostic (8.86e-2)" "unprognostic (3.50e-2)" "unprognostic (3.44e-2)" "unprognostic (5.71e-2)" "unprognostic (7.96e-2)" "unprognostic (2.46e-2)" "unprognostic (9.53e-3)" "unprognostic (7.02e-3)" "unprognostic (2.06e-1)" "unprognostic (6.25e-2)" "unprognostic (1.77e-2)" "unprognostic (1.77e-1)" "unprognostic (1.74e-2)" "unprognostic (1.67e-1)" "unprognostic (3.86e-2)" "unprognostic (9.28e-2)" "unprognostic (3.22e-2)" 67.3 147.8 33.4 49.1 31.2 44.9 60.3 47.4 35.4 127.2 26.7 97.7 79.5 67.4 75.3 55.0 72.4 50.2 60.9 35.8 31.8 66.1 193.2 77.8 40.8 41.4 36.4 56.9 80.6 50.7 48.5 47.9 38.1 146.8 102.7 21.6 97.6 69.8 92.3 46.7 79.4 64.1 33.0 69.2 107.1 25.3 41.3 83.1 75.2 91.9 55.0 58.3 54.3 34.0 120.2 112.8 95.0 211.6 353.3 262.0 51.9 239.5 179.3 105.5 97.4 159.5 120.4 114.8 166.9 406.4 181.7 43.2 68.5 316.8 123.3 92.0 67.5 70.7 156.1 86.1 258.9 33.3 21.6 223.8 128.6 155.8 143.8 173.8 171.0 117.8 42.6 156.8 177.1 150.4 96.5 57.6 56.0 283.7 101.4 327.4 62.9 358.5 245.2 68.6 52.9 96.0 82.7 234.7 120.6 91.1 98.0 37.4 132.4 171.3 69.1 165.9 99.2 246.8 294.0 47.5 236.9 78.3 76.2 3.7 7.5 19.2 3.1 10.5 5.2 9.3 1.6 2.1 6.1 6.2 1.0 2.3 30.6 14.3 14.3 3.1 1.0 5.1 33.4 31.2 47.4 35.4 35.8 31.8 41.4 36.4 38.1 33.0 41.3 34.0 41.9 57.7 29.5 22.9 62.0 22.8 32.1 22.7 14.8 37.2 51.2 35.1 32.9 68.6 29.4 49.7 16.7 20.7 44.3 83.6 21.5 101.9 11.5 36.2 48.0 33.5 26.0 25.9 35.4 60.8 90.3 47.2 49.5 77.9 23.5 64.4 37.5 247.8 41.1 21.9 41.8 202.9 36.7 77.0 105.2 33.8 65.0 54.8 7.2 30.0 91.1 39.0 36.0 47.7 30.6 86.9 59.3 58.3 96.2 74.2 95.0 38.5 28.4 12.6 39.5 56.1 41.1 1.9 10.5 27.2 26.9 9.0 25.1 103.5 73.3 47.8 ERGIC2 "Erv41, PTX1" ENSG00000087502 "ERGIC and golgi 2" Q96RQ1 12 29337352-29381189 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 383.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049695 Approved Supported "Nucleoli rim,Golgi apparatus,Vesicles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 18: U-2197 - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "Nucleoli rim" "HPA049695: AB_2680855" "unprognostic (1.62e-2)" "unprognostic (3.50e-2)" "unprognostic (5.53e-2)" "unprognostic (3.56e-1)" "unprognostic (1.45e-1)" "unprognostic (5.19e-3)" "prognostic unfavorable (8.06e-6)" "unprognostic (3.70e-2)" "unprognostic (2.32e-2)" "prognostic favorable (8.18e-4)" "prognostic unfavorable (7.02e-6)" "unprognostic (2.67e-1)" "prognostic unfavorable (3.76e-6)" "unprognostic (6.02e-2)" "unprognostic (2.08e-1)" "unprognostic (3.19e-2)" "unprognostic (2.64e-1)" 38.5 32.5 22.7 37.8 24.6 10.5 46.0 25.1 29.0 34.4 20.8 37.1 34.4 34.4 50.1 46.0 24.2 33.1 52.4 22.6 25.9 30.6 47.6 26.3 33.8 24.9 23.9 26.9 40.2 47.2 20.7 53.1 24.3 39.5 33.7 29.4 49.2 34.5 33.8 19.2 34.9 39.3 25.4 26.7 32.6 57.8 24.4 35.0 45.1 47.0 43.6 50.1 22.1 34.4 96.7 87.0 69.1 46.8 94.8 111.5 170.1 153.1 123.4 92.7 98.3 115.7 157.6 51.3 149.1 120.7 168.7 98.7 66.0 98.3 146.4 112.6 69.4 84.0 114.6 68.3 55.7 121.2 70.0 79.1 75.9 115.8 116.7 169.3 71.8 69.8 70.5 144.6 122.6 52.3 60.3 126.2 98.9 101.3 235.0 54.9 189.9 107.6 75.5 140.1 26.5 43.2 77.2 86.5 91.5 145.9 168.0 96.7 81.8 124.1 108.1 169.1 167.6 106.4 145.5 106.0 103.7 87.3 105.3 92.3 50.2 70.6 84.7 79.9 102.9 83.2 107.6 101.2 55.1 71.0 106.6 90.3 181.1 72.1 101.1 120.9 130.8 90.1 22.7 24.6 25.1 29.0 22.6 25.9 24.9 23.9 24.3 25.4 24.4 34.4 54.6 28.9 28.6 20.9 74.3 57.9 68.9 144.1 39.9 54.8 57.2 55.1 61.7 38.6 99.0 53.3 54.2 119.2 60.8 19.4 49.0 72.7 383.0 48.7 66.5 43.7 41.8 44.8 39.2 62.8 120.6 73.0 25.5 54.6 55.8 44.2 34.6 50.2 56.4 48.8 37.8 33.5 87.5 25.5 40.2 51.9 52.5 37.1 62.2 14.0 41.6 69.5 52.5 32.2 48.3 58.1 20.5 59.8 154.0 85.7 32.4 49.5 64.6 60.0 32.9 58.5 105.7 75.0 36.3 49.4 66.3 156.2 68.0 54.0 34.7 78.8 ERI1 "3'HEXO, THEX1" ENSG00000104626 "Exoribonuclease 1" Q8IV48 8 9002147-9116746 "Predicted intracellular proteins" "RNA-mediated gene silencing, rRNA processing" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 46.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033838, HPA055548, HPA056074" Uncertain Approved Vesicles,Microtubules NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 12: Non-specific - Cell cycle regulation" Microtubules Vesicles "CAB033838: AB_2098575, HPA055548: AB_2682845, HPA056074: AB_2683029" "unprognostic (2.49e-1)" "unprognostic (1.13e-1)" "prognostic favorable (8.05e-5)" "unprognostic (1.96e-2)" "unprognostic (2.79e-2)" "unprognostic (2.61e-3)" "unprognostic (1.08e-3)" "unprognostic (2.90e-1)" "unprognostic (5.50e-2)" "unprognostic (1.49e-1)" "unprognostic (1.25e-3)" "unprognostic (4.23e-1)" "prognostic unfavorable (1.42e-4)" "unprognostic (4.27e-2)" "unprognostic (3.57e-1)" "unprognostic (8.75e-2)" "unprognostic (2.36e-2)" 5.3 3.1 3.1 6.5 3.8 13.0 4.8 3.7 4.1 4.3 3.5 3.8 4.7 4.7 2.5 4.3 3.9 3.9 2.8 3.0 3.5 4.2 4.4 5.1 7.4 4.5 3.9 4.2 3.0 4.2 2.5 6.7 3.7 3.2 4.6 11.3 3.8 3.2 2.4 3.2 3.8 5.1 3.8 5.0 3.6 9.1 3.8 6.9 2.9 2.7 7.4 6.2 3.5 4.1 32.3 19.9 17.2 13.1 13.4 21.7 23.5 27.4 14.4 19.6 24.1 14.8 14.4 36.7 7.0 15.7 32.7 11.2 15.1 18.5 27.3 15.1 10.8 20.3 15.8 11.5 13.7 15.6 28.6 12.9 6.1 16.3 14.4 10.9 26.8 21.6 23.3 22.6 22.8 10.5 47.2 19.3 20.0 24.2 12.1 20.1 25.1 13.7 25.2 45.6 2.4 18.8 16.4 12.5 13.8 12.1 9.3 13.9 23.2 20.7 21.4 39.5 21.6 4.9 18.1 31.9 15.3 22.2 16.5 6.4 4.6 3.4 4.2 5.1 4.3 5.3 4.9 4.4 3.9 3.9 3.8 3.6 3.3 6.0 3.5 2.9 9.8 3.5 3.1 3.8 3.7 4.1 3.0 3.5 4.5 3.9 3.7 3.8 3.8 4.1 9.2 3.2 8.1 17.6 9.7 18.2 9.6 6.7 3.4 17.4 8.6 5.0 5.7 2.8 10.1 3.7 14.6 25.3 11.3 7.4 3.9 9.0 46.9 14.8 14.4 8.6 3.6 18.7 11.4 12.0 27.6 9.1 8.6 23.3 8.2 7.7 11.4 4.8 13.5 5.0 9.7 5.2 8.2 9.7 15.9 16.7 6.5 12.9 10.6 9.4 11.9 8.0 6.2 9.5 16.7 11.2 5.6 9.1 11.2 6.3 4.3 8.2 9.1 21.6 13.1 7.8 7.5 43.6 45.6 6.1 10.1 20.8 11.7 5.9 6.8 3.8 ERICH2 ENSG00000204334 "Glutamate rich 2" A1L162 2 170783786-170798971 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 163.9" "Cell type enriched" "Detected in many" 7 "Early spermatids: 2216.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "hTCEpi: 61.5" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "olfactory bulb: 33.1" HPA061010 Approved "Nucleoli fibrillar center,Vesicles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoli fibrillar center" Vesicles "HPA061010: " "unprognostic (1.02e-1)" "unprognostic (1.19e-2)" "unprognostic (2.26e-1)" "prognostic favorable (9.49e-4)" "unprognostic (7.57e-3)" "unprognostic (6.61e-2)" "unprognostic (9.62e-3)" "unprognostic (6.96e-2)" "unprognostic (1.05e-1)" "unprognostic (2.27e-2)" "unprognostic (1.12e-2)" "unprognostic (2.83e-1)" "prognostic unfavorable (8.98e-7)" "unprognostic (1.03e-1)" "unprognostic (5.28e-3)" "unprognostic (7.35e-2)" "unprognostic (2.76e-1)" 1.4 1.8 5.8 0.2 6.3 0.0 4.3 6.0 7.3 6.2 15.0 0.8 0.1 4.9 3.6 0.6 9.5 1.8 3.9 5.4 7.0 3.5 5.4 12.1 0.3 5.2 5.7 2.2 2.9 7.9 1.4 0.4 5.3 2.2 0.7 6.9 2.5 2.2 1.1 0.6 0.3 1.3 5.0 0.1 3.9 163.9 5.7 0.3 18.6 3.5 0.6 1.1 0.9 5.3 9.5 0.0 0.1 7.7 0.0 0.0 0.4 0.0 0.0 1.5 3.1 7.9 1.9 0.0 0.3 0.0 3.4 0.2 2.0 0.7 0.1 1.3 2.0 4.1 0.0 0.1 7.8 0.4 0.5 1.2 61.5 0.0 14.1 0.2 0.0 1.5 9.2 0.0 0.0 3.3 0.0 0.8 9.5 11.3 1.6 0.0 1.5 0.0 4.4 0.2 1.1 2.0 5.6 0.1 2.4 1.8 1.3 1.3 0.0 2.0 1.7 0.0 0.9 0.0 0.0 0.0 7.7 3.8 6.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 6.3 6.0 7.3 5.4 7.0 5.2 5.7 5.3 5.0 5.7 5.3 0.2 6.4 24.4 8.1 0.1 0.3 0.6 1.7 0.0 1.6 1.0 2.0 2.0 2.8 2.3 1.8 0.0 0.0 0.0 0.1 13.7 0.9 2216.6 25.7 3.6 0.9 7.7 0.0 4.4 1.8 0.2 1.0 0.0 1.3 0.0 0.7 0.0 2.5 0.0 0.0 12.7 1.6 2.0 0.0 0.0 302.9 9.6 0.9 0.0 1.9 0.0 2.0 0.0 6.6 4.0 1.3 0.0 7.5 0.0 0.2 0.0 0.7 21.5 0.5 6.6 0.8 1.0 39.1 10.8 0.0 0.1 0.0 0.1 0.2 0.4 0.1 ERV3-1 "envR, ERV-R, ERV3, H-PLK, HERV-R" ENSG00000213462 "Endogenous retrovirus group 3 member 1, envelope" Q14264 7 64990356-65006743 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 7.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 27.7" "HPA017209, HPA046508" Enhanced Approved Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 68: Epididymis - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 52: Non-specific - Transcription" Vesicles "HPA017209: AB_2732419, HPA046508: AB_2732525" "unprognostic (2.74e-2)" "unprognostic (1.84e-1)" "unprognostic (2.11e-1)" "unprognostic (1.27e-2)" "unprognostic (4.48e-1)" "unprognostic (2.03e-1)" "unprognostic (7.00e-2)" "unprognostic (1.79e-1)" "unprognostic (4.05e-3)" "unprognostic (3.55e-1)" "unprognostic (1.57e-2)" "unprognostic (4.45e-2)" "unprognostic (4.27e-3)" "unprognostic (2.11e-1)" "unprognostic (2.19e-1)" "unprognostic (9.39e-2)" "unprognostic (1.88e-2)" 22.8 33.0 4.8 8.5 4.5 9.3 15.0 4.1 6.4 10.0 5.1 5.7 3.5 10.0 32.5 15.2 8.0 16.4 6.2 4.7 6.2 4.8 3.2 9.7 5.7 6.2 7.9 7.3 5.3 15.3 8.2 13.4 5.4 7.3 5.7 13.5 12.1 7.5 3.6 12.3 4.5 7.6 4.8 6.9 6.3 8.7 5.9 6.6 7.6 1.8 7.4 6.2 11.5 5.1 3.3 1.0 17.4 27.7 11.3 4.7 12.4 5.7 6.3 2.0 4.6 1.2 20.5 5.5 5.3 2.2 4.0 3.9 2.6 1.5 3.2 4.1 1.5 2.8 1.6 11.5 1.0 6.7 3.7 5.1 1.6 1.8 0.6 10.4 11.6 6.0 12.7 10.3 8.1 8.1 4.9 5.0 5.1 10.8 1.2 11.4 0.7 3.7 3.5 6.8 3.6 16.8 6.2 1.9 0.7 18.9 4.7 16.4 9.2 6.7 1.0 5.1 2.8 3.2 7.8 1.6 5.7 20.8 4.1 0.0 1.0 2.4 0.6 1.8 0.5 0.4 0.1 0.4 0.8 0.5 0.3 0.4 7.0 1.1 0.5 0.4 1.2 0.6 4.8 4.5 4.1 6.4 4.7 6.2 6.2 7.9 5.4 4.8 5.9 5.1 7.1 3.2 13.1 17.9 32.5 4.2 15.6 17.0 7.4 24.8 13.7 10.4 2.1 24.3 25.5 16.5 29.2 16.5 21.6 4.4 9.8 14.4 7.3 6.2 8.6 10.9 13.8 19.4 12.2 17.9 12.7 8.3 12.8 5.9 8.2 20.4 13.6 3.6 9.7 18.5 13.0 9.1 16.2 21.8 16.5 4.8 11.5 19.8 10.6 14.0 16.7 11.3 36.0 24.1 14.0 17.6 7.8 9.8 10.0 12.5 15.4 4.9 14.0 21.4 6.6 7.6 8.7 12.2 11.8 8.6 5.7 40.2 20.5 10.7 6.7 31.1 ESPL1 "ESP1, KIAA0165, SEPA" ENSG00000135476 "Extra spindle pole bodies like 1, separase" Q14674 12 53268299-53293638 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Chromosome partition" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.5;esophagus: 15.4;lymphoid tissue: 10.7" "Cell type enhanced" "Detected in many" "Ionocytes: 22.4;Proximal enterocytes: 22.6;Squamous epithelial cells: 7.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "CAB012185, HPA073188" Approved Supported Nucleoplasm,Vesicles NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 45: Enterocytes - Digestion" Nucleoplasm Vesicles "CAB012185: AB_304056, HPA073188: " "unprognostic (1.57e-1)" "unprognostic (3.56e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (5.32e-5)" "unprognostic (2.91e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (2.01e-5)" "prognostic unfavorable (7.14e-4)" "unprognostic (1.59e-2)" "unprognostic (2.48e-1)" "unprognostic (4.17e-3)" "unprognostic (1.18e-2)" "unprognostic (7.42e-13)" "prognostic favorable (7.10e-4)" "unprognostic (2.39e-1)" "unprognostic (7.41e-2)" "unprognostic (1.42e-1)" 0.4 0.2 0.0 2.4 0.0 8.5 0.5 0.0 0.0 3.5 0.0 1.5 3.9 0.2 0.0 15.4 0.2 0.4 0.1 0.0 0.0 0.9 0.6 0.4 4.4 0.0 0.0 0.1 0.1 0.0 0.0 1.1 0.0 0.1 1.4 0.0 2.0 0.1 0.0 2.6 4.3 0.7 0.0 1.0 0.9 6.2 0.1 10.7 0.1 0.0 4.9 0.6 5.9 0.0 27.8 23.6 27.6 21.1 0.6 1.9 17.5 15.9 8.6 28.8 19.2 15.8 22.7 49.9 9.5 6.8 17.4 20.2 32.6 9.9 14.3 13.7 32.8 30.6 24.1 11.1 0.1 19.5 25.2 0.6 0.6 15.5 7.6 2.8 15.4 22.2 42.6 41.0 9.1 29.2 30.6 16.4 22.5 14.5 12.9 29.3 30.2 21.4 4.2 11.6 18.9 15.8 11.9 20.4 10.1 13.0 36.9 12.7 8.2 14.5 27.2 11.9 25.5 32.5 29.7 31.9 8.2 19.0 27.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.5 0.0 0.0 0.3 0.6 0.9 0.3 0.5 0.6 0.0 1.0 1.3 0.9 0.0 0.4 3.7 0.0 1.9 0.6 2.7 0.0 0.2 0.8 0.2 0.8 1.0 3.5 1.3 0.7 0.0 2.3 1.1 3.6 0.7 0.0 4.4 0.7 6.8 2.6 0.0 0.4 2.7 22.4 0.6 2.1 1.2 0.0 1.3 0.0 1.0 0.0 0.0 0.0 0.0 0.5 1.5 1.3 0.4 2.1 0.4 22.6 6.6 0.2 0.0 0.0 0.4 0.9 5.5 4.1 7.4 0.6 0.3 0.4 0.1 2.8 0.4 ESPN DFNB36 ENSG00000187017 Espin B1AK53 1 6424776-6461367 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing Actin-binding "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 129.1;retina: 117.8;testis: 145.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 175.5;Early spermatids: 137.5;Late spermatids: 461.6;Muller glia cells: 272.5;Paneth cells: 186.3;Proximal enterocytes: 512.1" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebellum: 13.4;thalamus: 6.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 48.9;Hep G2: 81.5;SK-BR-3: 160.1;T-47d: 53.6" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "cerebellum: 2.6" "HPA028674, HPA060220" Enhanced Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA028674: AB_10601316, HPA060220: AB_2684224" "unprognostic (5.06e-2)" "unprognostic (1.18e-2)" "unprognostic (2.69e-1)" "unprognostic (1.28e-1)" "unprognostic (2.19e-2)" "unprognostic (1.41e-1)" "unprognostic (1.59e-1)" "unprognostic (2.28e-1)" "unprognostic (1.16e-1)" "unprognostic (5.71e-2)" "unprognostic (7.48e-3)" "unprognostic (5.53e-2)" "unprognostic (6.26e-3)" "unprognostic (5.51e-2)" "unprognostic (1.16e-1)" "unprognostic (3.04e-2)" "unprognostic (1.17e-2)" 0.6 5.7 0.4 2.6 1.0 28.0 9.2 13.4 1.0 30.3 0.2 28.2 90.4 2.4 39.9 34.3 18.6 0.3 0.9 0.4 1.7 63.4 129.1 3.2 0.3 0.6 1.3 0.4 0.9 26.8 42.1 0.9 1.1 10.0 6.8 117.8 9.4 6.2 0.8 91.7 89.5 0.8 0.3 0.9 2.7 145.3 6.1 1.6 0.4 0.0 1.7 1.3 22.3 0.5 14.1 0.7 0.6 0.1 0.0 0.0 48.9 0.0 0.0 0.2 0.0 29.9 1.5 0.5 6.5 0.0 0.1 32.6 2.3 0.1 0.0 2.0 0.7 0.4 0.7 81.5 0.0 0.6 2.7 0.1 0.6 0.0 0.0 0.0 0.0 1.0 17.6 0.0 0.0 28.2 0.2 1.0 0.6 3.8 12.2 0.0 0.4 10.9 0.2 0.1 21.0 0.7 3.7 160.1 5.0 0.3 53.6 7.4 15.6 0.1 0.8 0.6 0.0 0.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 1.0 13.4 1.0 0.4 1.7 0.6 1.3 1.1 0.3 6.1 0.5 0.2 0.0 0.6 0.0 0.8 7.8 2.4 4.5 12.5 5.6 10.7 3.9 1.4 11.5 3.8 9.2 68.8 3.0 0.2 175.5 13.7 0.2 137.5 19.1 0.9 0.8 6.0 8.2 0.2 3.1 0.5 0.3 5.6 12.4 0.0 0.0 3.9 109.4 0.2 0.0 0.2 36.3 8.2 3.2 0.9 461.6 3.7 1.5 0.0 0.0 0.0 272.5 0.0 0.0 0.1 0.1 186.3 2.2 0.0 1.6 512.1 102.2 9.0 72.5 0.0 0.0 0.2 12.3 3.9 17.6 22.7 6.6 1.5 0.0 35.3 2.9 ESR1 "ER-alpha, Era, ESR, NR3A1" ENSG00000091831 "Estrogen receptor 1" P03372 6 151656691-152129619 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 83.8;endometrium 1: 110.9;fallopian tube: 64.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 86.6;Endometrial ciliated cells: 77.9;Endometrial stromal cells: 79.9;Glandular and luminal cells: 98.9;Hepatocytes: 52.1;Horizontal cells: 62.2;Skeletal myocytes: 56.7" "Cancer enhanced" "Detected in many" "breast cancer: 40.2;endometrial cancer: 24.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "MCF7: 46.0;T-47d: 57.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB000037, HPA000449, HPA000450, CAB055099, CAB072858" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" Vesicles Nucleoplasm "CAB000037: AB_563706, CAB055099: AB_2101946, CAB072858: AB_2665701, HPA000449: AB_1078753, HPA000450: AB_1078754" "unprognostic (8.28e-2)" "unprognostic (3.02e-2)" "unprognostic (1.43e-2)" "prognostic favorable (5.47e-7)" "unprognostic (4.79e-1)" "unprognostic (2.43e-3)" "unprognostic (4.10e-5)" "unprognostic (9.92e-2)" "unprognostic (2.20e-1)" "unprognostic (7.17e-2)" "unprognostic (7.35e-2)" "unprognostic (3.45e-1)" "unprognostic (1.20e-2)" "unprognostic (7.91e-3)" "unprognostic (6.45e-2)" "unprognostic (1.25e-1)" "unprognostic (1.52e-1)" 4.2 1.8 3.2 1.5 1.3 0.8 29.1 2.9 1.3 83.8 3.2 0.9 0.4 110.9 1.2 0.5 64.9 1.2 1.8 0.6 6.7 2.8 16.9 2.0 1.6 0.4 0.5 9.0 1.0 0.2 6.6 0.4 0.3 6.1 0.5 3.5 0.9 9.8 5.8 1.1 0.8 50.4 0.2 1.7 0.6 2.3 5.9 1.0 3.4 2.6 2.3 2.1 46.9 0.3 0.6 0.0 0.1 0.1 0.1 1.9 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.2 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 0.6 0.0 0.0 0.0 1.2 0.1 46.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.7 0.0 3.3 0.1 0.0 0.0 0.6 0.0 0.2 57.4 0.0 0.1 0.2 0.2 0.5 0.0 5.2 1.1 0.1 0.2 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 3.2 1.3 2.9 1.3 0.6 6.7 0.4 0.5 0.3 0.2 5.9 0.3 0.6 0.0 1.1 1.3 2.3 1.0 1.7 0.0 0.0 3.9 86.6 16.4 4.4 0.0 1.0 0.0 8.4 0.1 0.4 0.1 1.9 0.0 40.1 77.9 79.9 2.7 1.8 0.0 4.5 0.2 0.1 11.3 0.0 98.9 2.5 36.9 5.0 52.1 0.9 62.2 5.4 0.0 0.0 4.0 3.1 10.3 4.1 2.5 1.8 1.0 0.2 2.4 0.0 25.1 0.6 0.1 0.0 2.2 8.5 0.6 0.0 3.7 1.3 4.6 0.0 56.7 11.7 1.8 1.3 0.4 1.7 0.1 2.2 4.8 0.1 6.8 ESR2 "ER-beta, Erb, NR3A2" ENSG00000140009 "Estrogen receptor 2" Q92731 14 64084232-64338112 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 6.1" "Cell type enhanced" "Detected in many" "Early spermatids: 61.4;Granulosa cells: 26.6;Late spermatids: 93.7;Rod photoreceptor cells: 35.6;Spermatocytes: 28.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "Karpas-707: 4.2;U-266/70: 9.8;U-698: 16.4" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 6.1" "HPA068406, CAB079300" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm Vesicles "CAB079300: , HPA068406: " "unprognostic (7.63e-3)" "unprognostic (2.28e-3)" "unprognostic (8.27e-3)" "unprognostic (5.41e-2)" "unprognostic (2.91e-2)" "unprognostic (1.06e-1)" "unprognostic (1.80e-1)" "unprognostic (4.38e-2)" "unprognostic (1.95e-1)" "unprognostic (8.75e-2)" "unprognostic (2.57e-2)" "unprognostic (1.65e-1)" "unprognostic (3.03e-5)" "unprognostic (1.57e-1)" "unprognostic (1.66e-1)" "unprognostic (4.21e-2)" "unprognostic (5.89e-2)" 1.5 6.1 1.2 1.2 0.6 1.0 0.9 3.0 0.8 1.4 3.5 0.9 1.0 1.2 0.4 0.7 1.0 0.5 0.6 0.5 0.9 1.5 0.7 0.6 2.1 0.7 0.6 5.4 2.1 0.1 0.8 0.2 1.0 1.5 1.0 2.0 0.8 0.2 1.4 1.0 1.3 0.3 0.3 1.8 1.0 5.7 1.7 2.5 0.6 0.2 1.6 1.1 0.6 0.9 0.8 0.4 0.7 0.6 0.0 0.1 1.5 0.2 0.0 0.1 0.1 0.3 0.9 3.1 0.1 0.1 0.4 1.0 0.8 0.0 0.1 0.7 0.4 0.3 1.0 0.1 0.1 0.1 0.3 0.0 0.0 0.1 0.2 0.2 0.3 1.1 0.5 4.2 0.2 0.8 0.5 0.2 0.7 0.6 0.4 0.5 0.4 0.3 0.1 1.3 2.2 0.6 0.4 0.2 1.1 0.4 0.7 0.1 0.5 0.4 1.0 0.2 0.1 9.8 3.1 16.4 0.2 0.1 0.8 0.3 0.1 0.5 0.3 0.2 0.2 0.5 0.2 0.4 0.0 0.7 0.4 0.3 0.6 0.2 0.3 1.1 0.2 0.1 1.2 0.6 3.0 0.8 0.5 0.9 0.7 0.6 1.0 0.3 1.7 0.9 0.9 6.4 0.0 6.8 5.5 0.3 2.2 0.4 2.8 1.6 0.3 0.1 0.9 4.3 0.9 0.0 6.2 0.7 5.2 0.1 0.0 0.3 61.4 3.5 0.9 3.0 0.0 0.4 12.4 0.7 0.5 2.2 0.0 4.9 1.3 26.6 1.1 0.1 0.1 0.0 17.9 0.8 0.0 0.0 0.3 93.7 0.9 0.2 1.8 7.5 0.1 0.9 6.2 10.6 7.6 0.5 0.1 1.2 16.6 3.8 0.4 0.1 1.7 35.6 0.0 1.5 1.4 28.0 1.4 0.5 0.1 1.1 3.0 16.4 0.8 1.8 ETV3 PE-1 ENSG00000117036 "ETS variant transcription factor 3" P41162 1 157121191-157138474 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 361.2;monocytes: 97.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004794, HPA073211" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Vesicles "HPA004794: AB_1078761, HPA073211: " "unprognostic (1.65e-1)" "unprognostic (2.37e-1)" "unprognostic (3.78e-2)" "unprognostic (4.39e-2)" "unprognostic (7.59e-2)" "unprognostic (5.23e-2)" "unprognostic (1.38e-2)" "unprognostic (3.30e-1)" "unprognostic (2.36e-2)" "unprognostic (5.37e-2)" "unprognostic (1.34e-2)" "unprognostic (8.02e-2)" "unprognostic (7.26e-3)" "unprognostic (1.18e-1)" "unprognostic (1.22e-1)" "unprognostic (8.97e-2)" "unprognostic (6.65e-2)" 13.7 7.7 6.6 11.1 6.6 24.0 12.1 7.9 20.1 8.3 5.3 8.7 15.1 9.3 7.5 15.6 7.8 12.7 7.4 8.3 8.1 6.6 6.6 12.6 10.1 7.7 6.5 11.5 6.4 23.9 5.0 12.8 7.0 10.2 9.5 5.7 9.2 8.5 9.4 31.5 14.6 10.1 7.1 10.0 10.0 9.4 7.4 10.8 7.9 8.8 12.5 17.6 11.4 7.1 11.9 11.4 11.6 10.1 17.3 11.3 9.9 10.9 11.4 10.5 9.7 12.2 11.6 14.2 13.4 13.4 5.6 18.0 12.8 16.7 13.8 31.0 8.1 11.9 12.2 6.7 10.3 19.0 18.1 12.5 19.2 15.7 13.3 8.5 11.1 8.8 13.9 10.2 12.0 15.7 5.8 10.7 38.6 16.9 8.7 8.7 13.8 16.3 8.1 43.9 9.8 19.0 11.9 28.1 29.5 20.7 14.4 20.7 18.8 13.5 11.9 13.2 13.7 24.6 13.5 16.7 15.5 10.9 45.2 6.3 4.6 3.3 4.5 4.2 6.2 2.1 3.9 4.5 4.5 2.4 3.9 3.5 5.4 4.2 4.2 1.2 3.3 2.6 6.6 6.6 7.9 20.1 8.3 8.1 7.7 6.5 7.0 7.1 7.4 7.1 22.9 35.3 16.2 3.6 20.4 70.4 18.4 20.2 71.7 2.3 18.2 14.4 9.4 5.7 24.3 12.9 10.4 7.5 37.2 22.1 0.0 6.4 9.4 18.1 18.0 19.4 10.7 5.9 8.1 6.3 9.0 16.3 15.3 29.5 22.2 6.4 15.4 8.3 8.7 1.7 6.9 12.5 10.2 13.2 361.2 7.3 4.1 69.0 16.0 5.6 97.0 3.9 10.3 6.0 4.4 10.4 13.4 4.5 25.3 16.5 16.0 3.2 29.7 6.3 13.1 16.4 15.4 10.2 9.4 64.2 78.7 14.9 40.4 6.0 14.4 51.4 EVA1A "FAM176A, FLJ13391, TMEM166" ENSG00000115363 "Eva-1 homolog A, regulator of programmed cell death" Q9H8M9 2 75469302-75569722 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "liver: 191.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 41.7;Cytotrophoblasts: 43.3;Hepatocytes: 78.1;Proximal tubular cells: 77.3;Syncytiotrophoblasts: 124.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 85.7;U-138 MG: 110.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008055 Approved Supported "Vesicles,Plasma membrane" NA Yes "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "Plasma membrane" "HPA008055: AB_1080308" "unprognostic (2.72e-1)" "unprognostic (2.61e-2)" "unprognostic (4.14e-3)" "unprognostic (1.01e-1)" "unprognostic (1.36e-2)" "unprognostic (3.60e-2)" "unprognostic (5.02e-2)" "unprognostic (1.77e-2)" "unprognostic (1.77e-1)" "prognostic favorable (5.67e-4)" "unprognostic (7.33e-2)" "unprognostic (1.22e-1)" "prognostic favorable (5.80e-4)" "unprognostic (8.19e-2)" "unprognostic (4.37e-2)" "unprognostic (2.43e-2)" "unprognostic (9.07e-2)" 1.1 0.5 0.2 1.1 0.9 0.1 3.4 0.6 0.5 9.8 0.2 0.7 1.7 2.8 9.6 0.4 3.7 1.2 1.6 0.2 0.3 20.0 191.6 20.7 0.4 1.1 0.5 0.5 23.8 7.6 1.1 17.3 0.9 0.9 0.7 0.5 8.9 2.2 1.2 2.7 1.8 2.0 0.7 10.8 0.6 2.9 0.8 5.1 1.8 1.6 0.3 0.8 0.8 0.8 1.0 14.5 1.5 0.4 3.1 21.2 1.4 68.0 45.3 59.2 30.1 0.5 1.2 0.1 6.3 85.7 54.2 9.4 1.7 14.4 36.8 0.0 1.1 0.0 2.5 45.7 2.2 0.0 0.1 15.0 8.3 73.2 33.3 59.0 37.2 0.0 0.0 0.0 46.1 0.0 0.1 0.0 3.3 0.2 23.5 7.9 0.1 0.0 32.5 0.5 0.9 1.6 6.2 0.4 53.7 2.2 0.2 0.3 31.0 110.3 46.3 2.0 71.9 0.7 0.1 0.3 62.5 0.0 59.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.6 0.5 0.2 0.3 1.1 0.5 0.9 0.7 0.8 0.8 6.1 41.7 35.4 1.0 0.9 2.8 13.7 14.3 3.4 1.2 11.7 12.3 0.3 1.5 23.0 11.0 0.0 43.3 0.4 0.1 27.4 30.5 12.2 13.3 1.4 4.8 1.8 0.0 1.1 16.1 25.9 4.7 0.0 11.4 0.0 0.0 2.2 78.1 3.5 0.0 0.9 1.1 4.1 0.8 1.2 9.4 0.3 0.6 28.4 2.8 0.1 0.0 0.0 1.5 0.9 9.7 0.0 0.7 0.0 12.3 0.5 77.3 1.7 0.1 0.0 2.2 9.0 2.2 0.9 1.1 0.9 124.8 1.1 0.0 1.6 10.5 EVI5 NB4S ENSG00000067208 "Ecotropic viral integration site 5" O60447 1 92508696-92792404 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 199.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027339 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus" Vesicles "HPA027339: AB_1848308" "unprognostic (1.23e-1)" "unprognostic (2.84e-1)" "unprognostic (4.29e-3)" "unprognostic (1.65e-1)" "unprognostic (4.94e-2)" "unprognostic (1.06e-1)" "unprognostic (5.13e-3)" "unprognostic (7.43e-2)" "unprognostic (1.12e-1)" "unprognostic (9.11e-2)" "unprognostic (9.04e-3)" "unprognostic (2.25e-1)" "unprognostic (6.15e-2)" "unprognostic (8.30e-2)" "unprognostic (5.40e-1)" "unprognostic (6.38e-2)" "unprognostic (2.35e-2)" 5.7 8.1 5.9 4.5 8.3 2.7 4.4 8.5 5.8 5.9 8.2 4.8 4.3 6.4 4.6 4.0 5.1 5.8 7.1 4.2 7.7 5.0 16.4 7.1 3.2 8.1 6.2 3.8 3.8 7.9 3.9 12.1 6.8 5.3 5.5 4.9 4.5 5.6 2.9 5.0 4.0 7.1 8.6 4.5 6.4 9.6 6.3 1.3 6.6 3.6 3.3 5.5 3.8 10.9 5.4 5.9 9.1 8.9 14.5 18.2 8.6 12.2 18.5 8.2 9.4 10.4 1.4 2.4 16.8 14.0 15.2 6.1 8.6 9.0 14.6 0.2 3.3 4.3 5.6 6.2 14.2 3.1 4.8 11.5 7.2 14.2 8.5 23.9 17.9 0.2 7.7 3.8 13.9 2.7 0.3 3.6 2.6 3.5 4.8 2.2 21.7 3.2 6.3 15.5 3.4 7.0 14.4 7.4 16.6 9.8 3.6 7.1 11.8 9.1 6.6 12.2 8.1 5.5 3.4 3.8 6.0 5.0 7.6 0.9 2.7 2.8 0.1 1.9 0.0 1.2 0.1 0.0 1.3 1.2 0.0 0.0 3.4 0.1 2.9 0.8 0.0 0.4 5.9 8.3 8.5 5.8 4.2 7.7 8.1 6.2 6.8 8.6 6.3 10.9 27.2 60.9 29.9 91.4 18.7 43.5 29.3 23.0 18.2 24.5 20.5 17.7 51.8 22.8 32.3 16.5 25.0 48.4 7.5 22.9 17.6 27.9 3.0 67.8 39.4 31.2 22.1 11.4 158.4 29.9 26.0 42.5 42.3 26.2 13.3 21.9 43.2 52.4 32.2 30.3 149.3 27.0 14.2 54.0 27.0 5.8 28.3 45.1 26.6 114.3 48.9 28.5 5.2 112.6 199.6 68.4 19.3 54.2 28.8 28.1 21.8 20.1 46.9 25.4 13.1 51.4 56.4 37.4 42.4 21.2 50.0 65.5 5.5 60.9 20.0 32.1 EVL RNB6 ENSG00000196405 Enah/Vasp-like Q9UI08 14 99971449-100144236 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 402.4;NK-cells: 591.2;Rod photoreceptor cells: 438.0;T-cells: 373.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 291.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018849, HPA019536, CAB033987" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Vesicles, Cytosol" "CAB033987: AB_2101264, HPA018849: AB_1848310, HPA019536: AB_2670180" "unprognostic (1.12e-3)" "unprognostic (5.03e-3)" "unprognostic (6.46e-3)" "unprognostic (2.70e-1)" "unprognostic (2.65e-1)" "unprognostic (2.27e-3)" "unprognostic (3.65e-2)" "unprognostic (2.35e-1)" "unprognostic (2.06e-1)" "unprognostic (6.35e-3)" "prognostic favorable (4.07e-6)" "unprognostic (3.50e-3)" "prognostic unfavorable (4.14e-6)" "unprognostic (7.97e-2)" "unprognostic (1.58e-1)" "unprognostic (8.69e-3)" "unprognostic (2.43e-1)" 38.8 31.3 130.5 91.9 135.1 50.1 58.1 105.0 185.5 44.4 66.3 46.6 29.2 64.8 49.5 30.6 63.7 42.0 53.0 136.9 108.8 42.6 90.3 63.2 159.0 103.1 110.1 51.6 40.8 19.7 98.6 29.1 106.1 52.1 24.2 204.6 41.2 32.0 33.2 41.0 69.9 62.0 92.5 107.7 43.3 31.6 115.5 179.4 37.9 28.8 126.2 43.1 32.8 121.2 15.2 14.2 107.1 30.3 22.4 58.5 59.7 18.9 26.5 14.2 18.7 0.8 11.4 30.9 24.9 19.2 10.5 0.4 49.0 36.3 16.8 30.4 32.6 51.9 11.5 8.4 18.0 16.2 116.7 31.6 18.9 9.1 35.8 29.3 38.3 117.3 25.5 2.3 15.7 22.7 291.7 89.6 19.7 13.1 21.8 65.4 58.7 5.5 17.2 0.6 120.8 73.1 14.3 22.0 7.2 24.6 17.7 47.4 27.7 11.2 16.5 66.9 12.8 55.3 44.1 87.9 14.9 27.1 19.7 2.3 2.6 27.4 20.2 13.9 15.1 9.6 22.6 19.2 4.3 13.2 26.3 24.4 0.6 18.0 16.5 0.8 41.4 10.6 130.5 135.1 105.0 185.5 136.9 108.8 103.1 110.1 106.1 92.5 115.5 121.2 26.4 28.9 42.3 45.1 155.2 20.8 22.2 10.8 12.0 125.4 70.4 50.5 4.7 22.8 14.2 12.9 402.4 22.6 215.3 1.0 31.3 12.9 4.2 40.1 51.9 47.5 8.4 31.1 119.9 14.0 12.0 30.5 20.4 26.2 17.1 45.1 39.3 102.2 144.8 77.4 121.1 3.7 8.2 82.5 76.6 12.0 24.8 92.5 26.6 100.2 42.0 89.1 591.2 86.0 66.1 11.6 2.9 49.7 53.3 17.4 2.6 14.2 41.9 438.0 6.6 29.8 33.9 14.1 28.4 8.7 31.4 14.6 373.3 13.5 3.8 15.9 EXOC2 "FLJ11026, SEC5L1, Sec5p" ENSG00000112685 "Exocyst complex component 2" Q96KP1 6 485154-693139 "Predicted intracellular proteins, RAS pathway related proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 75.8;Inhibitory neurons: 80.1;Microglial cells: 68.4;Oligodendrocytes: 73.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032093 Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA032093: AB_10611964" "unprognostic (1.61e-1)" "unprognostic (4.69e-1)" "unprognostic (1.52e-1)" "unprognostic (9.32e-2)" "unprognostic (1.91e-2)" "unprognostic (2.48e-1)" "unprognostic (1.82e-3)" "unprognostic (1.34e-1)" "unprognostic (1.29e-1)" "unprognostic (1.30e-1)" "unprognostic (5.32e-2)" "unprognostic (2.02e-1)" "unprognostic (8.79e-2)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "unprognostic (2.20e-1)" 10.2 8.3 11.0 11.5 11.7 6.6 10.9 11.4 11.2 10.1 11.6 9.1 8.6 8.7 5.2 12.2 6.5 8.9 11.6 11.2 11.5 9.3 10.3 11.3 13.4 11.6 11.6 7.8 6.6 11.6 8.2 18.0 12.5 7.9 10.0 13.4 8.0 7.9 10.1 11.8 9.3 9.2 11.0 13.1 8.9 16.1 11.3 18.6 14.2 10.4 14.1 10.8 9.1 14.4 21.0 15.2 26.0 28.5 23.2 20.8 15.7 18.5 21.5 21.7 25.8 20.4 11.0 15.5 44.0 22.3 32.7 17.7 29.2 32.2 25.7 48.4 30.9 19.8 18.5 20.4 29.1 21.2 18.8 18.1 25.9 15.5 18.0 21.4 36.9 30.0 39.4 11.1 27.3 18.1 28.6 20.6 26.4 18.6 15.1 26.6 22.5 31.3 19.5 22.4 25.4 14.9 14.8 9.0 29.1 48.4 23.2 12.9 54.1 19.6 14.1 24.6 17.4 27.2 56.8 16.4 19.8 17.4 61.0 11.6 9.0 10.2 17.1 11.0 20.9 13.5 17.2 18.3 14.1 14.5 16.2 15.7 2.8 14.8 17.7 11.1 21.1 14.4 11.0 11.7 11.4 11.2 11.2 11.5 11.6 11.6 12.5 11.0 11.3 14.4 12.6 3.2 14.5 35.6 15.9 4.8 3.8 6.2 6.2 9.0 10.1 9.3 8.6 2.8 6.5 5.5 8.4 16.0 18.5 6.1 7.9 6.2 11.0 7.3 7.0 11.1 2.4 8.2 75.8 5.1 7.1 7.6 6.1 8.2 5.1 11.8 8.6 8.2 10.0 8.4 80.1 6.8 12.2 9.0 5.8 3.8 6.8 8.7 5.4 68.4 10.8 4.6 13.4 49.3 73.4 6.9 5.1 9.1 11.3 6.4 4.1 8.2 9.0 9.3 0.0 7.3 8.9 21.8 17.5 9.9 7.7 12.9 18.3 7.4 5.9 6.0 EXOC3L1 "EXOC3L, FLJ35539, FLJ35587" ENSG00000179044 "Exocyst complex component 3 like 1" Q86VI1 16 67184379-67190185 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 44.7" "Cell type enhanced" "Detected in many" "Adipocytes: 26.4;Endothelial cells: 19.6;Granulosa cells: 20.8;Hepatic stellate cells: 28.9;Leydig cells: 15.5;Peritubular cells: 18.4;Theca cells: 32.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.7;HUVEC TERT2: 3.5;SCLC-21H: 6.4;SuSa: 2.1;TIME: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA029574 Uncertain Approved "Vesicles,Plasma membrane" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" "HPA029574: AB_10602495" "unprognostic (1.15e-2)" "unprognostic (4.91e-2)" "unprognostic (6.87e-3)" "unprognostic (2.09e-3)" "unprognostic (2.33e-1)" "unprognostic (2.46e-2)" "unprognostic (6.77e-2)" "unprognostic (3.98e-2)" "unprognostic (1.55e-1)" "unprognostic (1.26e-2)" "unprognostic (6.48e-3)" "unprognostic (2.88e-1)" "unprognostic (6.64e-3)" "unprognostic (3.40e-1)" "unprognostic (1.23e-1)" "unprognostic (3.26e-1)" "unprognostic (1.35e-1)" 6.4 4.6 0.5 1.8 0.5 0.0 4.1 1.0 0.8 2.6 0.0 1.6 0.9 2.8 0.1 1.3 1.8 1.1 5.4 0.5 0.5 7.3 2.1 10.0 1.4 0.8 0.2 3.6 1.6 0.8 2.0 5.9 1.1 2.4 0.4 0.2 1.6 0.6 2.1 1.2 1.7 0.9 0.1 44.7 1.5 2.1 0.4 0.1 7.1 0.8 0.2 1.7 1.3 0.1 0.1 0.0 0.7 0.2 0.0 0.0 1.7 0.3 0.0 0.0 0.0 0.8 0.1 0.0 1.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 3.5 0.4 0.3 0.0 0.1 0.1 0.2 0.0 0.2 0.0 0.4 0.8 0.7 0.1 0.0 0.1 6.4 0.8 0.8 0.1 0.0 2.1 0.6 0.0 2.5 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.5 0.5 1.0 0.8 0.5 0.5 0.8 0.2 1.1 0.1 0.4 0.1 26.4 0.0 0.0 0.3 0.3 0.9 2.1 2.8 5.7 1.5 3.0 5.2 1.6 0.0 0.4 3.7 0.0 0.6 0.2 4.6 7.9 1.0 2.0 0.1 0.3 19.6 1.2 2.7 0.1 3.7 4.3 2.6 1.5 0.4 0.0 20.8 28.9 1.4 0.8 3.3 0.3 3.4 2.0 1.9 0.2 5.5 15.5 1.8 0.0 1.0 4.0 0.3 0.0 1.0 0.0 0.6 3.1 18.4 0.0 0.4 8.9 0.2 0.3 0.9 0.0 0.3 1.1 4.0 8.6 1.2 2.0 0.8 0.2 32.5 2.7 1.6 EXOC3L2 "FLJ36147, XTP7" ENSG00000283632 "Exocyst complex component 3 like 2" 19 45212370-45245407 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "kidney: 19.0;thyroid gland: 17.9" "Group enriched" "Detected in some" 4 "Adipocytes: 15.3;Endothelial cells: 17.7;Hepatic stellate cells: 51.4;Theca cells: 21.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HEL: 19.1;K-562: 16.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041595, HPA061110" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Nucleoplasm, Golgi apparatus, Cytosol" "HPA041595: AB_10794521, HPA061110: AB_2684431" 4.3 8.3 0.3 2.1 0.6 1.6 2.9 0.5 0.4 4.0 1.6 2.7 2.4 4.9 0.4 1.9 2.8 2.3 2.3 0.4 0.3 19.0 2.7 2.7 1.1 0.7 0.5 0.9 2.7 3.3 5.0 0.4 0.5 5.2 0.7 0.1 1.8 2.2 0.9 2.1 3.2 1.9 0.3 8.3 2.9 3.3 0.4 0.4 17.9 0.3 0.5 3.2 2.4 0.7 0.1 0.3 2.5 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.3 0.1 2.2 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.1 19.1 0.6 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 16.6 0.2 0.0 0.2 0.0 0.0 0.1 0.1 0.5 1.1 0.0 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.1 1.0 0.1 0.3 0.6 0.8 1.5 0.2 0.1 0.2 0.1 0.0 0.1 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.5 0.4 0.4 0.3 0.7 0.5 0.5 0.3 0.4 0.7 15.3 0.0 1.3 0.7 0.7 0.4 0.3 0.0 0.0 0.7 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 17.7 0.0 0.0 1.5 0.0 0.0 0.5 0.0 0.2 0.0 0.4 51.4 0.3 0.0 0.0 1.1 0.6 0.0 1.6 0.0 0.0 1.8 2.8 0.0 0.0 0.1 0.2 2.1 0.5 0.7 0.0 0.0 1.9 0.1 0.2 0.1 0.1 0.0 0.2 0.0 0.3 0.6 0.4 6.2 0.2 0.9 0.0 0.1 21.2 0.0 0.3 EXOC6 "DKFZp761I2124, EXOC6A, FLJ1125, MGC33397, SEC15L, SEC15L1, Sec15p" ENSG00000138190 "Exocyst complex component 6" Q8TAG9 10 92826831-93059493 "Plasma proteins, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "retina: 164.2" "Cell type enhanced" "Detected in all" "Excitatory neurons: 181.7;Microglial cells: 146.1;Oligodendrocyte precursor cells: 157.3;Rod photoreceptor cells: 177.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 30.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 113.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036285, HPA059111" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles Nucleoplasm "HPA036285: AB_10673617, HPA059111: AB_2683907" "unprognostic (1.41e-1)" "unprognostic (1.39e-3)" "unprognostic (5.20e-2)" "unprognostic (2.65e-1)" "unprognostic (1.10e-1)" "unprognostic (1.64e-1)" "unprognostic (1.16e-3)" "unprognostic (7.21e-3)" "unprognostic (3.84e-1)" "unprognostic (2.70e-1)" "unprognostic (1.66e-1)" "unprognostic (8.13e-2)" "prognostic favorable (4.66e-4)" "unprognostic (2.12e-2)" "unprognostic (1.00e-1)" "unprognostic (1.42e-1)" "unprognostic (6.41e-2)" 8.7 14.4 5.9 8.2 7.5 12.9 8.0 7.7 8.6 6.5 8.0 9.6 8.1 6.1 5.7 4.2 5.8 10.1 7.1 8.2 6.0 6.4 10.1 10.7 9.5 3.4 2.4 3.9 10.0 6.3 6.1 37.4 3.7 8.6 10.2 164.2 5.6 4.3 31.8 5.0 9.5 7.7 3.3 9.1 7.0 9.9 6.1 8.5 28.4 19.7 8.2 10.1 3.5 7.1 19.8 24.3 25.7 16.8 1.3 1.6 9.1 9.0 24.9 8.1 9.7 9.1 16.5 22.5 19.0 4.3 6.6 12.3 20.8 5.7 10.1 20.1 20.9 35.1 8.3 11.7 9.6 36.4 30.6 2.2 3.0 7.2 4.8 14.6 113.8 14.6 29.2 14.5 4.0 10.7 15.3 23.2 3.5 40.2 7.0 22.5 11.2 11.6 17.4 13.2 8.5 11.9 9.2 9.2 11.8 6.4 18.2 18.8 22.4 0.6 8.2 7.5 14.7 10.8 12.4 18.1 2.8 41.6 9.3 6.2 4.9 15.2 3.0 3.9 3.0 6.7 3.4 2.8 5.1 6.6 2.7 3.2 30.6 2.8 3.9 11.1 3.3 2.4 5.9 7.5 7.7 8.6 8.2 6.0 3.4 2.4 3.7 3.3 6.1 7.1 28.3 16.0 16.7 33.6 27.6 3.3 10.7 8.6 3.4 40.2 9.8 6.5 12.0 20.0 15.0 16.5 39.6 22.9 24.1 14.3 5.9 28.3 5.4 8.8 3.0 53.1 25.6 39.2 181.7 15.4 7.8 7.8 13.7 16.5 10.8 24.3 77.1 14.2 21.4 23.5 100.3 16.6 14.2 18.2 12.5 12.6 4.4 18.9 5.4 146.1 22.8 27.1 19.6 157.3 84.7 14.1 10.3 14.7 13.8 14.1 10.8 8.4 10.0 177.8 13.1 13.6 9.0 25.0 25.5 4.9 4.8 20.5 18.4 29.8 11.9 15.8 EXOC7 "BLOM4, EXO70, Exo70p, KIAA1067, YJL085W" ENSG00000182473 "Exocyst complex component 7" Q9UPT5 17 76081016-76121576 "Human disease related genes, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022840, HPA022842" Supported Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 52: Non-specific - Ribosome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Cytosol "Vesicles, Plasma membrane" "HPA022840: AB_1848316, HPA022842: AB_1848317" "unprognostic (5.20e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-1)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "unprognostic (3.49e-2)" "unprognostic (2.37e-2)" "unprognostic (1.88e-1)" "unprognostic (1.30e-1)" "unprognostic (1.02e-1)" "unprognostic (2.47e-2)" "unprognostic (7.39e-3)" "unprognostic (1.53e-2)" "unprognostic (1.73e-1)" "unprognostic (1.19e-1)" "unprognostic (1.05e-1)" "unprognostic (1.18e-1)" 40.4 31.4 36.0 32.7 37.0 53.2 31.2 31.4 36.7 39.3 34.1 40.1 32.5 40.1 33.1 52.3 52.3 35.4 47.2 36.8 35.5 31.9 30.2 35.9 32.7 35.4 34.3 49.6 41.1 61.2 41.0 35.3 36.5 48.1 27.9 24.7 50.6 43.1 43.0 37.0 34.7 43.5 31.9 32.4 30.3 24.9 36.4 43.5 43.0 41.4 32.3 44.3 30.1 34.8 65.6 79.4 71.9 58.5 66.6 47.0 74.5 58.9 77.6 103.9 74.7 67.5 43.0 33.7 42.0 103.0 65.6 52.7 43.9 57.1 69.0 29.3 59.1 55.8 64.0 72.3 46.4 62.9 55.7 66.1 44.3 80.5 39.2 73.5 116.9 59.8 38.1 33.7 65.6 59.8 102.1 27.8 37.8 49.5 83.4 54.0 123.3 34.6 59.7 133.6 38.9 91.4 66.5 48.6 44.6 68.8 79.7 51.0 77.5 111.3 66.3 74.1 65.8 46.0 18.2 31.2 66.4 28.0 59.0 55.1 41.1 66.1 35.5 57.4 24.4 26.7 26.9 30.4 28.9 26.9 27.7 23.9 46.2 36.4 79.7 12.3 32.0 44.9 36.0 37.0 31.4 36.7 36.8 35.5 35.4 34.3 36.5 31.9 36.4 34.8 31.0 19.2 35.0 36.6 37.7 19.8 40.1 40.8 31.3 87.6 30.2 28.8 7.5 28.6 41.4 40.5 143.9 51.5 37.5 47.6 33.2 38.3 22.4 35.1 25.8 27.1 48.9 48.6 26.2 37.1 29.0 31.6 27.0 34.4 41.1 65.0 30.7 27.0 37.7 67.3 31.1 43.8 54.9 29.6 21.3 52.2 37.3 26.9 24.9 15.0 36.8 52.1 56.7 44.2 35.0 44.6 41.4 38.4 15.7 41.5 62.8 35.3 43.7 108.8 46.0 27.8 49.5 32.1 16.6 20.3 19.9 71.1 35.8 56.6 29.8 44.8 EXOSC4 "FLJ20591, hRrp41p, p12A, RRP41, RRP41A, Rrp41p, SKI6, Ski6p" ENSG00000178896 "Exosome component 4" Q9NPD3 8 144078648-144080648 "Plasma proteins, Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 94.9" "Group enriched" "Detected in many" 4 "Early spermatids: 320.6;Late spermatids: 856.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 430.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024792, HPA065103" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" Vesicles "HPA024792: AB_1848325, HPA065103: " "unprognostic (2.32e-1)" "unprognostic (1.55e-2)" "unprognostic (3.06e-1)" "unprognostic (3.53e-2)" "unprognostic (1.33e-1)" "unprognostic (2.29e-2)" "unprognostic (6.58e-3)" "unprognostic (1.26e-1)" "unprognostic (8.36e-2)" "prognostic favorable (2.23e-4)" "unprognostic (4.32e-2)" "unprognostic (1.41e-1)" "unprognostic (2.30e-2)" "unprognostic (5.18e-2)" "unprognostic (1.23e-1)" "unprognostic (2.71e-1)" "unprognostic (5.11e-2)" 19.3 31.2 15.1 11.4 16.5 14.9 16.9 16.0 23.4 13.1 16.1 18.8 15.4 17.0 5.0 27.5 16.1 7.2 23.7 15.6 15.0 23.6 35.0 16.0 12.1 16.8 14.9 12.3 18.8 10.3 17.6 9.2 15.5 18.8 5.7 3.5 26.6 12.5 21.2 22.1 15.2 6.1 15.4 23.8 24.0 94.9 15.8 10.1 13.9 8.2 6.6 17.4 15.2 15.9 51.8 104.8 18.1 44.2 15.6 11.7 51.8 39.9 15.2 28.9 28.9 73.4 33.4 28.9 54.6 15.5 21.0 40.4 33.8 40.5 8.3 42.5 117.8 42.7 77.9 83.3 25.9 31.4 48.6 16.9 40.9 33.2 26.2 11.4 14.8 32.0 68.8 19.8 23.8 177.8 51.4 62.0 47.6 51.2 430.6 21.7 30.2 74.8 27.7 48.3 57.6 75.4 46.6 59.7 95.4 9.3 68.1 49.0 15.2 29.9 66.3 73.6 68.1 52.4 67.8 37.5 43.1 50.8 47.7 61.5 78.3 34.1 37.4 76.6 38.7 59.7 29.3 37.4 75.0 60.2 37.7 36.2 22.9 45.6 43.0 97.4 36.1 49.5 15.1 16.5 16.0 23.4 15.6 15.0 16.8 14.9 15.5 15.4 15.8 15.9 16.3 9.6 21.3 2.9 17.8 94.4 45.2 58.6 45.5 10.0 40.7 41.4 22.3 24.3 31.9 27.6 8.4 48.2 17.2 46.6 123.3 50.6 320.6 23.8 28.3 25.5 25.9 24.6 3.2 46.3 44.2 24.7 25.0 18.8 14.0 21.0 19.2 54.9 44.7 6.7 3.3 35.6 48.8 29.8 40.7 856.7 18.6 29.9 35.6 0.0 45.7 23.5 14.4 3.0 3.6 61.7 52.4 21.1 32.5 55.5 41.0 102.5 31.7 8.2 13.1 14.7 43.5 97.0 34.7 48.1 87.9 48.2 12.8 37.8 47.1 48.7 EXOSC8 "bA421P11.3, CIP3, EAP2, OIP2, p9, RRP43, Rrp43p" ENSG00000120699 "Exosome component 8" Q96B26 13 36998816-37009614 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "rRNA processing" RNA-binding "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 163.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034240, HPA039702, HPA043942, HPA075230" Uncertain Supported "Nucleoli fibrillar center,Mitotic chromosome,Vesicles" Yes NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli fibrillar center, Mitotic chromosome, Vesicles" "CAB034240: AB_2101977, HPA039702: AB_2676634, HPA043942: AB_2678742, HPA075230: " "unprognostic (8.67e-2)" "unprognostic (9.39e-2)" "unprognostic (5.77e-2)" "unprognostic (1.03e-1)" "unprognostic (2.58e-2)" "unprognostic (1.24e-2)" "unprognostic (1.02e-1)" "unprognostic (4.01e-2)" "unprognostic (3.24e-3)" "unprognostic (2.45e-2)" "unprognostic (2.35e-2)" "unprognostic (7.32e-3)" "prognostic unfavorable (8.39e-7)" "unprognostic (9.58e-3)" "unprognostic (7.42e-2)" "unprognostic (1.10e-1)" "unprognostic (4.51e-1)" 15.0 14.2 16.6 19.1 17.6 27.5 18.8 17.9 24.3 16.8 16.6 17.0 12.6 14.2 14.4 18.2 16.8 8.4 19.4 16.9 17.8 17.9 19.8 13.5 21.2 17.5 17.1 16.4 13.9 11.6 10.8 15.6 18.1 14.2 19.0 15.3 11.3 13.2 24.2 16.6 14.0 16.6 17.3 17.5 15.3 27.8 17.0 31.5 12.3 24.8 25.1 16.2 14.7 19.7 47.5 33.5 97.7 66.4 28.4 30.1 73.8 68.9 48.8 93.2 74.2 72.7 93.6 65.1 29.8 38.2 91.4 64.7 92.7 67.1 111.5 96.3 73.9 174.8 34.2 87.4 37.0 148.3 58.9 17.4 51.3 62.6 100.2 24.1 72.8 93.6 86.6 41.3 66.4 59.1 78.6 116.6 101.4 113.2 44.0 48.5 98.6 53.5 51.1 30.8 23.8 46.1 38.1 44.5 65.3 51.1 35.4 117.6 37.2 35.5 49.1 42.9 95.5 23.3 29.4 135.7 56.0 104.1 66.8 28.9 29.8 23.5 42.8 39.6 44.8 66.0 54.1 50.5 33.9 57.2 67.1 62.7 6.0 46.2 41.7 54.8 54.6 52.4 16.6 17.6 17.9 24.3 16.9 17.8 17.5 17.1 18.1 17.3 17.0 19.7 43.5 32.1 38.9 15.7 40.1 36.1 51.6 109.6 25.0 20.8 25.0 50.0 50.2 18.6 69.5 11.0 8.4 86.8 46.8 13.1 56.7 58.1 115.7 21.5 31.4 39.4 13.2 57.9 7.0 52.1 92.3 41.8 19.4 20.6 103.6 46.2 18.5 17.4 46.8 28.6 8.6 19.1 79.3 13.6 34.2 54.6 40.7 26.0 26.6 10.3 32.6 27.1 35.0 17.1 22.0 36.1 16.4 36.5 38.8 29.0 18.0 26.6 53.4 32.0 26.3 38.8 52.1 163.3 85.9 29.0 36.2 67.0 38.7 42.7 30.2 37.7 EXTL1 "EXTL, MGC70794" ENSG00000158008 "Exostosin like glycosyltransferase 1" Q92935 1 26019884-26036464 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 14.2;skeletal muscle: 12.7;tongue: 29.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 15.3;Breast glandular cells: 8.8;Excitatory neurons: 22.7;Horizontal cells: 10.1;Melanocytes: 7.2;Oligodendrocyte precursor cells: 10.6" "Cancer enriched" "Detected in some" 13 "melanoma: 21.7" "Group enriched" "Detected in many" 11 "amygdala: 10.3;basal ganglia: 9.8;cerebral cortex: 14.2;hippocampal formation: 11.5;white matter: 6.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "WM-115: 150.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010726, HPA037749" Uncertain Approved Vesicles,Centrosome "Intracellular and membrane" NA NA 79000 "Cluster 47: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 30: Mammary glandular cells - Lactation" Centrosome Vesicles "HPA010726: , HPA037749: AB_10805350" "unprognostic (2.00e-1)" "unprognostic (1.10e-2)" "unprognostic (8.16e-3)" "unprognostic (1.47e-2)" "unprognostic (2.47e-2)" "unprognostic (6.14e-3)" "unprognostic (3.78e-2)" "unprognostic (1.99e-1)" "unprognostic (1.99e-1)" "unprognostic (6.70e-2)" "unprognostic (1.44e-2)" "unprognostic (3.46e-1)" "unprognostic (1.12e-2)" "unprognostic (1.40e-3)" "unprognostic (2.27e-2)" "unprognostic (2.91e-1)" "unprognostic (1.35e-2)" 0.2 1.0 10.3 0.0 9.8 0.0 0.8 0.0 14.2 0.4 0.0 1.0 0.1 3.6 0.1 0.5 0.7 0.3 3.5 11.5 0.0 0.4 0.0 0.2 0.2 0.1 0.6 1.1 1.5 0.0 0.9 0.3 0.4 0.4 0.0 0.8 0.5 0.2 12.7 2.3 0.3 1.3 0.0 3.5 0.3 0.6 0.9 0.0 0.2 29.8 0.0 0.3 0.4 6.9 0.2 0.0 0.1 0.6 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.1 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.7 0.0 0.2 0.2 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 14.7 0.0 0.0 0.0 0.2 0.6 0.0 0.2 2.4 0.2 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 150.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 9.8 0.0 14.2 11.5 0.0 0.1 0.6 0.4 0.0 0.9 6.9 0.1 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 15.3 8.8 1.8 3.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.1 0.0 0.0 22.7 0.0 0.0 0.4 0.0 0.2 0.0 0.4 0.0 0.0 0.1 10.1 5.1 0.0 0.0 0.0 0.3 0.6 1.5 0.0 7.2 2.8 0.0 0.4 0.0 10.6 1.9 0.0 0.0 2.6 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.4 0.4 0.2 0.2 0.0 0.0 1.0 0.0 1.1 0.1 0.1 F11 FXI ENSG00000088926 "Coagulation factor XI" P03951 4 186266189-186289681 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Heparin-binding, Hydrolase, Protease, Serine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 243.2" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 27.6;Hepatocytes: 75.7" "Cancer enriched" "Detected in some" 13 "liver cancer: 16.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 9 "Hep G2: 6.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA039808 Approved Vesicles "Secreted to blood" NA NA 4400000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA039808: AB_2676693" "unprognostic (1.28e-1)" "unprognostic (3.15e-1)" "prognostic favorable (3.29e-5)" "unprognostic (1.88e-1)" "unprognostic (2.08e-1)" "unprognostic (2.11e-1)" "unprognostic (1.85e-3)" "unprognostic (2.91e-2)" "unprognostic (7.65e-2)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.5 0.2 0.0 0.2 17.1 0.2 0.1 0.0 0.0 13.1 0.0 0.2 0.0 27.6 243.2 8.4 0.0 0.0 0.3 0.3 58.9 0.0 0.2 0.0 0.1 0.0 0.1 0.7 0.0 0.2 0.7 0.0 8.7 0.0 0.0 0.1 0.8 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.2 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.0 27.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 4.3 2.5 1.8 0.0 0.0 0.2 0.3 11.7 2.3 0.0 0.0 0.0 0.1 0.0 5.3 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 75.7 0.0 0.0 0.6 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 2.1 0.0 0.0 0.0 0.0 1.1 5.5 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 F3 "CD142, TF" ENSG00000117525 "Coagulation factor III, tissue factor" P13726 1 94529173-94541759 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Blood coagulation, Hemostasis" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 902.0;Exocrine glandular cells: 464.1;Pancreatic endocrine cells: 1755.7;Peritubular cells: 530.7;Urothelial cells: 497.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 1062.0;HaCaT: 490.7;HBEC3-KT: 1270.5;U-2197: 473.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009438, HPA049292, HPA069132" Uncertain Approved Vesicles "Secreted to blood" NA NA 603000 "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB009438: AB_668005, HPA049292: AB_2680701, HPA069132: AB_2686092" "unprognostic (3.86e-2)" "unprognostic (1.19e-1)" "unprognostic (8.04e-2)" "unprognostic (1.64e-1)" "unprognostic (2.69e-2)" "unprognostic (1.23e-3)" "unprognostic (4.93e-2)" "unprognostic (8.00e-2)" "unprognostic (5.88e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.02e-8)" "unprognostic (4.84e-2)" "unprognostic (4.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.08e-1)" 118.2 21.3 53.1 28.8 69.9 4.1 70.1 53.2 74.4 48.0 44.1 52.2 36.8 61.1 44.2 41.3 89.9 59.6 36.8 54.0 62.7 18.0 5.1 59.8 12.9 77.7 62.6 114.8 96.5 17.2 81.2 133.4 57.1 56.8 42.1 72.6 93.3 60.4 7.6 56.0 47.3 10.7 60.8 7.2 42.6 34.6 62.0 5.6 62.6 9.9 14.9 65.4 73.0 55.4 1062.0 1.8 2.2 0.5 108.0 53.1 57.2 147.0 87.6 155.4 167.9 18.6 220.6 0.0 73.3 183.5 33.4 490.7 13.2 1270.5 254.4 0.9 1.6 0.0 35.0 3.3 35.9 0.7 0.6 91.9 28.2 73.8 356.5 293.7 1.1 1.1 0.9 0.8 110.0 1.8 1.5 22.3 9.8 6.8 2.2 1.2 10.3 0.5 19.8 3.2 1.3 2.6 117.4 48.3 3.6 29.6 1.3 13.9 0.3 93.7 2.5 473.0 44.6 0.9 1.3 0.9 71.9 5.7 3.8 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 53.1 69.9 53.2 74.4 54.0 62.7 77.7 62.6 57.1 60.8 62.0 55.4 9.4 131.4 243.3 196.6 0.7 16.3 902.0 359.6 2.2 3.6 29.6 20.4 26.4 18.6 380.3 14.7 0.0 16.5 0.6 20.9 0.0 133.5 8.6 61.3 125.0 13.2 13.1 0.0 0.4 464.1 6.0 125.3 23.0 123.0 2.5 38.1 7.5 0.4 6.1 3.3 4.6 70.3 65.1 2.8 5.2 14.5 281.1 9.1 3.6 45.9 2.1 340.6 0.0 15.6 1.2 1755.7 15.5 530.7 1.2 121.6 10.1 0.4 92.0 16.1 6.6 39.3 76.7 1.7 4.4 6.4 7.5 7.7 7.3 7.9 14.3 497.9 FAAP24 "C19orf40, FLJ46828, MGC32020" ENSG00000131944 "FA core complex associated protein 24" Q9BTP7 19 32972209-32978229 "Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 14.6;Spermatocytes: 22.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041168 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Vesicles "HPA041168: AB_10960496" "unprognostic (1.18e-2)" "unprognostic (1.22e-2)" "unprognostic (1.34e-1)" "prognostic unfavorable (4.38e-4)" "unprognostic (6.52e-2)" "unprognostic (2.73e-1)" "unprognostic (2.58e-3)" "unprognostic (3.76e-2)" "unprognostic (1.88e-2)" "unprognostic (3.98e-2)" "unprognostic (2.82e-3)" "unprognostic (3.54e-2)" "prognostic unfavorable (4.00e-7)" "unprognostic (4.37e-3)" "unprognostic (5.30e-1)" "unprognostic (2.31e-3)" "unprognostic (2.15e-1)" 1.7 1.4 0.8 2.6 0.7 3.5 1.8 1.2 1.1 1.0 1.1 1.7 1.8 1.3 2.4 1.8 1.4 2.3 0.7 0.8 0.6 1.2 1.4 1.4 3.1 1.4 0.6 2.5 0.9 0.4 0.8 1.6 1.0 4.8 2.5 0.5 1.2 1.1 0.5 2.8 2.2 1.5 0.4 2.4 1.4 6.2 0.9 2.6 1.8 0.2 3.5 1.5 1.2 2.2 6.0 15.0 5.7 9.3 3.2 6.3 4.9 7.7 8.2 14.5 18.8 10.3 9.7 7.0 11.2 3.2 11.4 4.2 11.7 5.9 11.5 19.4 5.4 15.3 5.8 7.6 1.7 5.2 7.5 3.5 3.5 9.0 5.3 2.3 5.9 11.2 8.2 7.1 11.1 6.7 11.6 7.1 2.6 8.7 6.7 10.2 5.1 3.9 2.9 3.6 5.9 4.9 8.7 9.9 6.1 6.2 6.6 13.7 3.5 14.2 6.6 6.2 7.2 5.5 12.4 9.6 10.1 11.9 9.6 15.3 5.7 8.8 3.2 6.9 3.8 6.4 4.0 4.9 3.6 6.2 3.6 5.2 13.9 7.1 7.8 6.9 5.6 3.2 0.8 0.7 1.2 1.1 0.8 0.6 1.4 0.6 1.0 0.4 0.9 2.2 1.7 3.2 1.1 0.0 3.0 0.0 3.3 0.0 1.8 1.5 3.9 3.6 0.5 2.8 1.3 3.7 2.1 11.1 6.5 1.2 1.9 1.6 7.2 4.4 3.0 2.1 1.2 7.4 0.0 8.0 14.6 3.1 0.5 6.3 1.3 7.1 3.6 0.4 8.2 5.0 0.0 2.4 0.0 5.1 0.0 12.3 3.4 3.5 0.0 0.0 7.0 0.6 2.1 0.0 0.0 4.2 2.4 3.4 2.6 3.2 3.5 1.0 0.0 1.0 0.0 2.7 2.2 22.6 8.3 2.7 0.0 5.1 2.5 5.8 2.7 2.6 FAM110A "bA371L19.3, C20orf55" ENSG00000125898 "Family with sequence similarity 110 member A" Q9BQ89 20 833715-857463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 71.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 71.7;Extravillous trophoblasts: 138.2;Langerhans cells: 74.2;Macrophages: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 543.5;eosinophil: 163.4;intermediate monocyte: 160.6;non-classical monocyte: 248.6" "Group enriched" "Detected in all" 9 "granulocytes: 543.5;monocytes: 248.6" "Cell line enhanced" "Detected in all" "SK-BR-3: 84.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB034110, HPA069240" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol Yes Yes "Cluster 10: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Vesicles" Cytosol "CAB034110: AB_1562838, HPA069240: AB_2686103" "unprognostic (6.33e-2)" "unprognostic (2.53e-2)" "unprognostic (1.57e-2)" "unprognostic (3.43e-2)" "unprognostic (1.81e-1)" "unprognostic (3.37e-2)" "unprognostic (4.90e-3)" "unprognostic (5.55e-2)" "unprognostic (6.01e-2)" "unprognostic (4.78e-2)" "unprognostic (2.35e-2)" "unprognostic (2.47e-1)" "prognostic unfavorable (4.42e-4)" "unprognostic (9.64e-3)" "unprognostic (1.17e-2)" "unprognostic (6.42e-3)" "unprognostic (4.21e-3)" 4.2 5.5 4.2 5.9 5.2 8.8 9.0 3.1 3.6 10.1 3.9 5.5 10.0 2.5 4.7 39.3 2.5 2.3 4.0 2.8 3.4 8.8 3.6 12.3 6.7 5.5 5.3 2.8 5.5 11.0 7.9 6.6 5.6 19.3 3.2 1.2 18.4 3.6 4.0 71.2 9.7 1.1 3.3 23.4 6.1 3.7 6.6 6.9 7.6 0.6 7.8 9.2 18.4 3.6 27.7 7.3 4.1 7.6 4.4 1.9 27.8 8.5 4.7 5.3 4.7 16.0 16.9 8.9 3.7 5.3 7.6 43.7 3.3 22.2 4.4 7.3 2.3 18.6 4.9 4.2 2.0 5.1 6.3 1.2 27.1 7.3 7.1 1.6 3.6 8.1 10.2 21.5 4.9 16.4 14.3 13.8 5.3 17.7 12.3 14.1 7.0 11.7 4.1 19.6 7.7 9.1 7.4 84.0 3.8 1.7 34.9 7.5 4.8 12.6 9.1 11.5 9.6 7.8 7.3 3.8 2.0 13.2 9.2 543.5 28.3 163.4 13.2 160.6 11.7 7.0 23.7 27.2 36.2 11.7 28.1 27.9 15.3 6.9 248.6 3.9 43.0 24.2 4.2 5.2 3.1 3.6 2.8 3.4 5.5 5.3 5.6 3.3 6.6 3.6 3.5 0.0 7.0 0.0 18.5 32.6 17.0 31.6 71.7 0.3 26.7 20.1 2.9 7.2 15.7 11.0 0.0 41.5 24.3 5.1 1.9 10.1 9.9 3.0 1.7 8.0 10.8 16.2 0.5 6.0 138.2 3.6 5.1 5.2 51.5 1.4 17.2 0.7 20.0 5.0 0.4 8.8 16.2 36.7 74.2 24.3 3.4 70.0 7.2 1.9 29.9 0.3 25.7 0.5 0.1 13.4 7.8 1.9 3.5 20.9 16.1 2.4 7.4 2.6 6.6 1.1 4.3 3.4 4.9 57.7 36.8 31.3 26.1 14.2 10.4 24.6 FAM114A2 "133K02, C5orf3" ENSG00000055147 "Family with sequence similarity 114 member A2" Q9NRY5 5 153990148-154038936 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 109.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035869, HPA035870" Approved Approved Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "HPA035869: AB_10669534, HPA035870: AB_10673222" "unprognostic (1.81e-1)" "unprognostic (2.65e-1)" "unprognostic (3.45e-2)" "unprognostic (3.27e-1)" "unprognostic (7.99e-2)" "unprognostic (8.21e-2)" "unprognostic (5.18e-3)" "unprognostic (6.70e-2)" "unprognostic (1.92e-2)" "unprognostic (2.66e-1)" "unprognostic (9.70e-3)" "unprognostic (4.37e-1)" "unprognostic (7.80e-2)" "unprognostic (1.38e-3)" "unprognostic (4.17e-2)" "unprognostic (5.90e-3)" "unprognostic (2.85e-2)" 14.1 12.6 7.6 13.8 7.7 9.1 12.6 7.1 7.7 10.7 9.3 9.9 12.1 10.8 16.6 13.4 9.6 10.2 19.3 6.7 9.7 15.4 16.2 11.7 15.9 8.5 8.8 10.1 14.6 22.1 8.5 13.4 8.7 12.1 10.8 13.2 14.3 11.6 19.9 9.3 11.8 15.4 8.4 14.3 12.8 37.6 9.9 14.2 13.5 16.1 17.2 12.0 8.1 8.1 15.7 20.4 21.5 33.8 29.6 27.5 19.5 37.1 25.8 26.9 37.2 15.2 22.6 19.7 34.7 27.5 18.8 13.1 18.8 36.1 32.5 22.1 21.0 25.2 12.2 11.1 34.8 22.3 25.0 24.9 22.0 24.3 43.5 19.7 38.3 25.6 16.2 30.1 35.3 15.1 25.5 9.2 9.7 16.7 9.9 21.9 29.6 30.4 20.5 10.8 5.0 17.8 26.8 28.7 38.2 22.6 38.5 16.1 35.7 24.9 17.6 23.0 22.5 45.4 39.7 27.9 29.5 30.4 27.3 38.1 14.6 35.7 15.6 18.2 17.9 15.5 12.6 18.2 14.5 17.9 16.0 15.4 7.2 17.6 23.3 13.2 16.0 11.9 7.6 7.7 7.1 7.7 6.7 9.7 8.5 8.8 8.7 8.4 9.9 8.1 22.6 9.6 11.5 9.1 14.9 6.2 5.7 9.5 11.4 10.5 9.2 6.5 26.9 10.0 8.2 11.0 4.2 22.4 8.5 4.8 7.9 12.3 45.3 9.6 13.1 19.8 5.4 24.0 10.4 12.5 16.2 15.0 11.7 8.7 17.2 12.9 10.4 19.8 17.7 10.1 12.9 8.2 6.1 17.7 8.7 14.8 11.1 11.5 14.2 15.0 13.2 25.0 12.3 18.1 11.7 9.1 2.9 9.8 19.2 5.4 12.4 15.4 12.3 15.6 6.6 10.4 14.5 109.6 38.5 11.4 6.8 18.3 11.2 14.1 6.0 3.6 FAM161B "C14orf44, FLJ31697" ENSG00000156050 "FAM161 centrosomal protein B" Q96MY7 14 73931501-73950414 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 62.9;Late spermatids: 142.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019125 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 21: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA019125: AB_1845570" "unprognostic (1.50e-1)" "unprognostic (9.03e-2)" "unprognostic (6.35e-2)" "unprognostic (1.99e-1)" "unprognostic (9.51e-2)" "unprognostic (1.79e-2)" "unprognostic (1.76e-3)" "unprognostic (5.54e-2)" "unprognostic (1.81e-1)" "unprognostic (1.57e-1)" "unprognostic (7.83e-2)" "unprognostic (1.53e-1)" "prognostic favorable (6.78e-4)" "unprognostic (1.26e-1)" "unprognostic (1.37e-1)" "unprognostic (7.35e-2)" "unprognostic (1.60e-1)" 2.7 8.7 6.6 1.7 6.6 1.2 4.8 5.8 8.2 5.3 3.4 3.9 3.3 5.2 4.3 4.1 5.5 2.7 5.4 6.4 5.9 7.2 5.1 2.8 1.8 6.8 5.7 12.8 2.2 4.3 7.6 2.4 7.1 6.0 2.7 10.1 2.8 5.2 7.9 2.1 3.3 3.4 5.5 3.1 3.3 18.8 6.1 1.9 4.2 4.8 1.8 5.5 3.8 6.6 2.1 1.6 2.2 3.4 4.7 3.5 2.0 3.6 2.8 6.0 5.8 1.5 2.6 3.3 2.3 4.2 2.5 3.9 0.9 1.7 4.1 9.2 1.8 1.6 1.6 1.7 4.0 1.1 2.3 2.6 3.4 6.1 2.2 4.4 2.7 3.4 1.0 1.6 4.3 3.3 3.1 4.2 0.5 1.4 3.5 2.1 2.9 1.3 3.1 3.1 2.7 2.5 5.1 2.3 3.1 1.6 8.1 1.5 2.9 12.4 5.6 3.1 2.2 3.3 2.2 2.1 6.3 1.9 2.2 3.2 1.3 1.9 1.1 0.3 1.3 0.7 1.2 1.7 0.2 0.9 0.6 0.4 0.4 1.3 0.4 0.3 0.7 0.9 6.6 6.6 5.8 8.2 6.4 5.9 6.8 5.7 7.1 5.5 6.1 6.6 3.5 3.2 4.8 4.9 3.0 0.6 2.1 1.0 3.4 8.9 3.7 3.8 3.4 0.0 3.2 1.8 4.2 1.5 1.9 3.5 0.0 1.0 62.9 5.9 3.9 2.2 0.0 1.7 7.3 1.6 1.1 4.6 7.1 4.5 0.0 5.0 2.5 0.7 2.9 3.3 8.6 4.1 2.0 1.2 0.7 142.7 3.4 1.4 1.8 2.8 2.2 8.0 6.2 5.5 2.9 1.2 0.8 9.4 1.4 0.8 4.3 4.2 9.4 16.7 6.6 5.2 4.2 11.0 6.1 0.6 0.9 2.2 3.3 9.6 1.4 0.9 FAM166C "C2orf70, LOC339778" ENSG00000173557 "Family with sequence similarity 166 member C" A6NJV1 2 26562585-26579532 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 7.6;testis: 26.6" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 1.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "OE19: 21.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA062453 Enhanced Approved "Nuclear membrane,Vesicles" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 21: OE19 - Mitochondria" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear membrane, Vesicles" "HPA062453: AB_2684769" "unprognostic (5.44e-2)" "unprognostic (9.30e-3)" "unprognostic (1.03e-1)" "unprognostic (4.06e-3)" "unprognostic (1.99e-2)" "unprognostic (9.40e-6)" "unprognostic (1.71e-1)" "unprognostic (4.70e-2)" "unprognostic (1.07e-1)" "prognostic favorable (6.49e-4)" "unprognostic (4.58e-2)" "unprognostic (1.52e-1)" "unprognostic (2.98e-1)" "unprognostic (2.01e-1)" "unprognostic (2.16e-3)" "unprognostic (7.08e-3)" 0.1 0.1 0.8 0.1 0.7 0.0 0.2 0.5 0.6 0.3 4.1 0.6 0.1 0.2 0.3 0.1 7.6 0.0 0.4 0.8 2.5 1.0 0.0 0.4 0.0 2.0 2.0 0.0 0.7 0.1 0.7 0.0 1.2 0.2 0.4 0.1 1.9 0.2 0.1 0.1 0.1 0.1 1.5 0.0 4.8 26.6 2.9 0.0 1.1 0.0 0.0 0.1 0.0 1.0 4.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 1.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 21.2 0.0 0.0 0.0 0.0 3.7 0.0 0.9 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.5 0.6 0.8 2.5 2.0 2.0 1.2 1.5 2.9 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM177A1 C14orf24 ENSG00000151327 "Family with sequence similarity 177 member A1" Q8N128 14 35044907-35113130 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 637.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053222, HPA055440" Uncertain Approved Nucleoplasm,Vesicles "Secreted to blood" NA NA 170000 "Cluster 1: Neutrophils - Mixed function" "Cluster 78: Testis - Spermatogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 24: Non-specific - Transcription regulation" Vesicles Nucleoplasm "HPA053222: AB_2682083, HPA055440: AB_2682817" "unprognostic (6.86e-2)" "unprognostic (2.03e-1)" "unprognostic (2.12e-1)" "unprognostic (7.01e-2)" "unprognostic (1.91e-2)" "prognostic unfavorable (9.70e-4)" "unprognostic (4.64e-3)" "unprognostic (6.28e-2)" "unprognostic (7.79e-2)" "prognostic favorable (8.51e-5)" "unprognostic (1.12e-2)" "unprognostic (7.22e-3)" "unprognostic (1.04e-1)" "unprognostic (2.56e-1)" "unprognostic (1.69e-1)" "unprognostic (8.28e-2)" "unprognostic (1.91e-1)" 45.3 43.2 36.8 30.0 50.1 49.6 38.2 45.3 46.5 44.2 36.9 81.5 57.2 29.4 29.6 49.7 26.8 37.7 78.1 39.0 51.3 61.3 77.0 68.6 20.2 52.4 50.6 28.2 49.4 30.6 47.4 27.3 49.1 63.1 71.5 31.3 43.4 36.1 48.3 41.3 54.6 42.3 45.0 23.6 42.5 86.2 47.0 21.6 48.0 32.8 23.2 46.7 37.7 57.0 63.4 51.2 38.0 31.3 64.6 64.6 46.7 101.3 55.8 52.4 57.1 52.2 82.6 25.1 68.1 98.9 71.1 65.8 47.1 58.5 66.7 73.5 28.8 19.5 63.8 179.5 79.4 30.7 44.9 58.5 75.3 63.5 49.5 76.7 60.6 46.7 47.7 79.8 102.5 91.5 38.0 28.1 30.9 100.9 65.2 21.9 52.7 35.9 95.2 68.7 52.1 45.9 119.3 94.2 81.3 75.2 87.2 23.9 71.3 67.5 59.2 76.6 53.2 59.3 79.8 31.2 42.3 20.5 68.0 79.9 43.9 79.2 31.0 36.7 36.5 45.0 40.3 35.7 34.8 35.8 31.7 31.4 167.5 32.6 31.9 50.8 60.0 30.4 36.8 50.1 45.3 46.5 39.0 51.3 52.4 50.6 49.1 45.0 47.0 57.0 126.7 240.4 176.3 6.5 87.4 160.7 199.4 200.4 83.6 35.8 119.0 118.4 147.8 67.2 168.1 104.8 27.1 71.0 322.2 329.3 119.3 121.9 637.1 235.5 86.6 116.4 133.8 36.0 10.7 249.6 118.0 80.5 107.0 426.4 82.3 43.1 82.5 235.6 75.5 23.5 13.4 189.5 144.5 61.1 130.9 505.9 54.0 85.4 149.4 8.4 125.1 45.3 48.4 9.0 28.4 364.6 220.1 53.0 133.3 211.4 273.7 347.2 177.8 45.5 46.0 65.2 106.2 189.3 106.8 93.1 171.5 123.3 215.7 30.4 224.2 229.5 FAM186A LOC121006 ENSG00000185958 "Family with sequence similarity 186 member A" A6NE01 12 50326230-50396622 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 14.2" "Cell type enriched" "Detected in some" 8 "Early spermatids: 521.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047128, HPA064735" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 78: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA047128: AB_10967726, HPA064735: " "unprognostic (1.01e-1)" "unprognostic (1.29e-1)" "unprognostic (1.25e-1)" "unprognostic (2.31e-1)" "unprognostic (1.88e-1)" "unprognostic (3.69e-2)" "unprognostic (3.48e-3)" "unprognostic (1.43e-2)" "unprognostic (1.30e-2)" "unprognostic (6.96e-2)" "unprognostic (4.65e-5)" "unprognostic (1.93e-1)" "unprognostic (2.42e-5)" "unprognostic (1.65e-1)" "unprognostic (1.32e-1)" "unprognostic (7.51e-2)" "unprognostic (3.22e-3)" 0.1 0.3 0.2 0.2 0.4 0.5 0.1 0.6 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.5 0.2 0.1 0.6 0.3 0.1 0.2 0.1 0.0 0.2 0.3 0.0 0.9 0.0 0.1 0.3 0.1 0.7 0.2 0.0 1.1 0.3 0.2 0.0 0.0 0.3 0.1 14.2 0.2 0.0 0.1 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.3 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.6 0.3 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.6 0.3 0.1 0.1 0.0 0.0 0.2 0.4 0.6 0.4 0.2 0.1 0.1 0.0 0.1 0.0 0.2 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 521.1 0.1 0.2 0.1 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 64.7 0.6 0.1 0.0 2.8 0.0 0.6 0.0 1.5 3.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 1.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM219A "bA573M23.5, C9orf25, FLJ39031" ENSG00000164970 "Family with sequence similarity 219 member A" Q8IW50 9 34398184-34458570 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 94.6" "Cell type enhanced" "Detected in many" "Horizontal cells: 53.8;Late spermatids: 35.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "HDLM-2: 96.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019338, HPA052909" Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA019338: AB_1845819, HPA052909: AB_2681986" "unprognostic (9.96e-3)" "unprognostic (2.16e-1)" "unprognostic (1.50e-2)" "unprognostic (1.23e-2)" "unprognostic (6.81e-2)" "unprognostic (4.07e-2)" "prognostic unfavorable (1.98e-5)" "unprognostic (2.71e-2)" "unprognostic (2.50e-1)" "unprognostic (2.95e-1)" "prognostic favorable (2.46e-4)" "unprognostic (3.46e-3)" "prognostic unfavorable (5.54e-5)" "unprognostic (2.04e-2)" "unprognostic (1.78e-1)" "unprognostic (3.34e-1)" "unprognostic (2.76e-1)" 19.8 14.0 82.5 9.0 79.4 3.8 17.5 72.4 88.0 18.5 25.9 17.0 5.4 22.5 6.2 9.8 15.7 5.6 29.9 75.9 77.5 15.7 12.7 18.8 6.5 90.0 84.8 15.3 13.2 6.4 26.3 13.4 94.6 16.3 4.6 19.3 12.1 7.0 42.7 16.2 11.9 11.9 83.8 15.1 12.7 9.7 82.9 8.3 14.9 12.6 5.0 17.7 15.7 85.4 27.9 10.6 24.5 14.0 22.3 8.5 23.8 16.5 12.4 14.0 17.7 7.4 6.3 6.1 16.6 16.1 27.7 11.4 19.6 10.6 14.0 96.0 11.2 2.5 14.6 8.0 12.5 6.1 13.6 9.0 10.5 21.0 11.7 17.4 23.4 10.6 6.1 29.6 11.0 5.6 9.5 8.5 15.8 3.8 15.6 12.1 4.1 5.3 10.1 5.9 7.8 24.8 14.3 10.3 8.5 22.2 5.2 6.1 28.0 15.4 11.9 32.3 23.2 7.8 12.0 5.1 44.2 13.9 27.8 0.6 0.1 1.1 0.3 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.5 0.2 0.2 0.1 0.4 0.1 82.5 79.4 72.4 88.0 75.9 77.5 90.0 84.8 94.6 83.8 82.9 85.4 14.3 6.4 3.3 17.3 3.3 6.2 3.7 5.6 4.0 21.1 5.1 2.9 11.7 1.5 2.5 3.7 4.2 9.4 4.3 2.1 0.0 6.1 13.8 2.0 6.0 17.4 10.8 0.4 28.6 5.1 16.8 7.8 6.1 2.8 2.5 3.4 9.3 2.8 5.9 53.8 31.8 2.3 8.2 5.5 2.6 35.1 3.7 4.1 8.8 15.0 4.5 9.3 3.1 22.1 15.9 6.6 1.7 5.7 3.0 5.1 1.3 3.0 2.3 11.0 6.6 5.2 9.1 9.9 3.8 3.0 6.5 20.7 3.5 2.9 0.9 2.7 FAM220A "ACPIN1, C7orf70, MGC12966, SIPAR" ENSG00000178397 "Family with sequence similarity 220 member A" Q7Z4H9 7 6329411-6348981 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 89.7;testis: 55.9" "Group enriched" "Detected in many" 13 "Early spermatids: 280.0;Late spermatids: 363.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055050 Approved Vesicles NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA055050: AB_2682684" "unprognostic (3.49e-2)" "unprognostic (3.53e-1)" "unprognostic (2.69e-2)" "unprognostic (9.79e-2)" "unprognostic (3.26e-2)" "unprognostic (4.02e-2)" "prognostic unfavorable (5.17e-6)" "unprognostic (2.78e-1)" "unprognostic (1.43e-2)" "unprognostic (2.36e-1)" "unprognostic (1.98e-1)" "unprognostic (1.51e-2)" "unprognostic (1.30e-1)" "unprognostic (8.84e-3)" "unprognostic (1.14e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (3.71e-2)" 7.1 8.6 13.6 6.9 14.7 2.6 8.3 17.5 17.0 9.1 9.3 6.2 5.4 10.3 7.4 11.5 7.6 7.6 13.8 15.3 13.6 8.2 6.4 6.2 9.9 11.7 12.7 10.7 9.8 19.2 0.6 7.9 12.4 8.0 5.3 11.5 8.4 8.3 89.7 10.1 4.9 9.3 12.5 7.9 6.1 55.9 13.7 12.0 11.7 39.1 10.4 9.6 0.5 13.4 26.9 16.6 11.9 28.0 27.0 22.7 13.1 13.4 16.6 15.9 18.5 10.5 14.6 22.2 15.1 15.9 31.8 19.2 18.2 11.3 20.6 15.5 11.7 7.3 10.0 12.6 29.2 13.5 10.8 12.7 37.5 11.9 28.5 15.3 15.0 16.4 14.6 20.7 13.9 20.9 8.4 24.7 27.8 14.0 21.4 21.6 17.9 18.7 14.7 9.6 12.1 21.0 18.8 23.0 28.6 23.9 22.1 34.9 11.4 12.5 28.5 20.6 17.5 19.7 37.2 23.2 14.6 24.1 39.3 6.6 4.2 8.0 4.7 3.5 4.4 9.1 5.4 6.5 7.7 7.7 8.4 6.8 2.0 12.9 3.8 6.8 6.6 3.7 13.6 14.7 17.5 17.0 15.3 13.6 11.7 12.7 12.4 12.5 13.7 13.4 4.1 3.2 1.1 1.3 8.1 7.8 4.9 6.2 12.0 2.9 6.0 6.9 9.2 0.0 8.2 1.8 6.2 6.3 5.4 3.8 1.9 4.9 280.0 6.0 5.5 4.6 6.1 7.8 4.7 4.8 7.5 6.8 7.7 4.8 1.3 4.4 6.4 3.5 6.2 0.0 4.7 4.2 4.1 6.8 10.5 363.4 8.4 7.4 3.6 2.8 7.1 5.2 6.2 4.0 3.9 4.8 2.1 13.2 3.9 5.5 3.3 2.8 3.4 2.3 0.0 6.3 5.4 23.7 11.4 10.3 10.1 8.2 5.2 3.9 3.4 6.7 FAM3B "2-21, C21orf11, C21orf76, D21M16SJHU19e, ORF9, PANDER, PRED44" ENSG00000183844 "FAM3 metabolism regulating signaling molecule B" P58499 21 41304212-41357727 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 142.6;pancreas: 212.3;salivary gland: 119.4;stomach 1: 114.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 304.6;Exocrine glandular cells: 399.9;Proximal enterocytes: 831.6" "Cancer enhanced" "Detected in many" "prostate cancer: 40.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 1.4;neutrophil: 2.8" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.8" "Cell line enhanced" "Detected in some" "CACO-2: 19.5;CAPAN-2: 11.7;Hep G2: 32.1;OE19: 27.3;RPMI-8226: 80.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015885, HPA029777, CAB034131" Enhanced Approved Vesicles "Secreted to blood" NA NA 2080000 250000 "Cluster 1: Neutrophils - Mixed function" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB034131: AB_2231472, HPA015885: AB_1848396, HPA029777: AB_2673194" "unprognostic (2.88e-1)" "unprognostic (3.31e-3)" "unprognostic (5.13e-2)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "unprognostic (6.32e-3)" "unprognostic (1.41e-1)" "unprognostic (8.79e-3)" "unprognostic (9.38e-2)" "unprognostic (1.70e-1)" "unprognostic (4.65e-1)" "unprognostic (3.78e-1)" "unprognostic (5.60e-3)" "unprognostic (1.57e-1)" "unprognostic (1.80e-1)" "unprognostic (1.78e-1)" "unprognostic (1.55e-3)" 1.5 0.1 0.0 2.5 0.1 0.8 17.7 0.1 0.3 4.9 1.3 5.9 142.6 0.3 22.1 56.2 17.2 16.2 0.6 0.1 0.1 17.9 2.6 9.3 1.5 0.1 0.1 0.2 212.3 0.5 5.4 15.2 0.1 37.9 0.1 0.0 119.4 8.7 0.1 2.3 135.0 0.5 0.1 0.6 114.9 6.9 0.1 3.1 8.0 0.0 16.8 34.4 16.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 19.5 11.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 32.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.4 0.9 27.3 0.0 0.2 0.0 80.6 0.0 5.8 0.4 0.4 0.0 0.7 0.4 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.3 1.4 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.0 0.3 0.7 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 1.0 22.4 25.7 0.0 0.8 1.3 17.0 2.9 1.2 0.0 101.3 123.1 0.2 102.9 36.5 66.2 0.0 304.6 1.4 2.7 25.4 172.1 25.2 0.2 0.1 2.5 0.0 0.0 0.1 399.9 11.1 3.4 147.3 0.7 1.3 0.6 0.4 0.3 27.0 0.0 0.1 120.9 42.7 5.0 15.8 11.5 0.6 3.9 5.4 1.9 2.1 0.0 0.0 0.0 0.1 144.6 169.0 0.4 0.2 64.9 831.6 0.7 22.4 0.0 0.0 0.4 1.8 28.0 8.1 29.1 1.3 161.3 0.9 0.0 125.2 130.5 FAM43A FLJ90022 ENSG00000185112 "Family with sequence similarity 43 member A" Q8N2R8 3 194685883-194689037 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 54.9" "Cell type enhanced" "Detected in many" "Adipocytes: 89.2;Endothelial cells: 102.4;Extravillous trophoblasts: 83.3;Hepatic stellate cells: 97.1;NK-cells: 75.2;Syncytiotrophoblasts: 162.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 4.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 123.7;NB-4: 72.8;PC-3: 56.9;TIME: 66.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048345 Uncertain Approved Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA048345: AB_2680367" "unprognostic (1.61e-1)" "unprognostic (1.11e-1)" "unprognostic (9.18e-2)" "unprognostic (1.90e-2)" "unprognostic (5.71e-3)" "unprognostic (5.13e-3)" "unprognostic (9.80e-2)" "unprognostic (8.28e-2)" "unprognostic (4.96e-2)" "unprognostic (1.38e-1)" "unprognostic (3.92e-3)" "unprognostic (1.74e-1)" "unprognostic (2.14e-1)" "unprognostic (1.15e-1)" "unprognostic (1.45e-1)" "unprognostic (2.91e-3)" "prognostic unfavorable (9.96e-4)" 25.2 4.8 8.3 5.1 5.6 3.7 15.7 6.9 14.1 16.1 4.0 15.7 1.4 13.0 1.2 15.4 15.1 4.0 30.3 11.7 6.5 41.4 5.8 9.7 10.0 33.2 9.6 4.5 3.0 1.4 8.7 11.2 34.8 22.1 2.3 0.8 8.0 2.7 6.0 25.2 11.6 3.7 7.3 54.9 8.3 4.4 8.3 1.3 8.0 4.0 6.3 17.2 25.1 6.9 0.3 1.8 1.4 1.1 23.3 11.4 10.4 3.8 8.6 0.1 0.0 0.8 0.3 1.3 37.4 11.6 8.5 3.8 2.3 1.0 0.1 0.9 6.4 4.7 10.8 1.3 1.8 1.2 13.5 3.0 4.8 0.5 0.1 0.6 123.7 0.2 2.8 2.5 0.3 1.9 0.0 72.8 6.0 12.8 56.9 6.0 0.4 0.6 0.1 0.2 35.6 3.0 2.4 2.3 7.5 2.4 1.5 15.7 66.3 1.2 1.9 1.6 0.8 0.2 1.5 3.5 0.7 34.3 24.0 2.2 0.6 1.3 0.5 0.5 0.7 1.2 0.3 0.5 0.8 2.5 0.0 0.2 0.9 1.6 0.5 4.5 0.2 0.3 8.3 5.6 6.9 14.1 11.7 6.5 33.2 9.6 34.8 7.3 8.3 6.9 89.2 0.0 2.5 0.0 26.7 4.0 21.4 6.7 4.6 16.0 10.6 7.0 35.1 0.0 4.0 1.8 8.4 21.1 38.3 39.6 7.9 7.8 0.3 3.2 19.5 102.4 6.6 0.4 3.5 1.8 83.3 30.1 8.6 4.0 15.2 3.8 97.1 1.4 6.0 0.0 7.3 8.0 24.4 13.1 3.9 1.3 16.4 9.3 12.4 28.1 7.7 2.2 75.2 0.0 2.6 7.0 19.1 9.8 8.5 20.3 1.0 0.4 1.4 2.8 26.3 5.2 20.8 0.6 14.2 6.5 4.0 162.4 16.0 3.0 11.0 12.6 FAM72A "LMPIP, MGC57827, p17, RP11-312O7.1, UGENE" ENSG00000196550 "Family with sequence similarity 72 member A" Q5TYM5 1 206186179-206204414 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.9" "Cell type enhanced" "Detected in many" "Early spermatids: 29.5;Kupffer cells: 18.2;Late spermatids: 30.2;Spermatocytes: 28.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA043271, HPA067321" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA Yes "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "Plasma membrane, Cytosol" "HPA043271: AB_2678402, HPA067321: " "unprognostic (3.61e-2)" "unprognostic (1.58e-1)" "unprognostic (1.80e-1)" "unprognostic (5.20e-5)" "unprognostic (3.61e-1)" "unprognostic (1.19e-3)" "unprognostic (1.01e-5)" "unprognostic (7.70e-3)" "unprognostic (1.45e-2)" "unprognostic (5.58e-3)" "unprognostic (2.87e-2)" "unprognostic (1.03e-1)" "unprognostic (4.44e-16)" "unprognostic (1.82e-1)" "unprognostic (1.94e-2)" "unprognostic (4.83e-2)" "unprognostic (3.89e-1)" 4.0 3.1 2.6 5.9 2.9 8.4 3.6 9.1 3.1 1.3 1.0 2.2 3.1 0.9 0.4 2.5 1.8 2.7 1.2 3.1 4.0 1.3 2.0 2.6 10.9 5.4 4.4 1.1 1.4 1.6 0.8 3.5 5.8 1.1 2.3 0.2 1.0 0.7 0.6 5.9 2.9 2.0 4.1 6.3 1.5 7.1 4.8 8.6 0.9 1.0 7.5 1.5 1.5 4.7 21.1 16.4 17.7 7.7 2.6 3.1 21.1 14.6 6.3 17.1 12.7 9.9 31.1 54.2 12.3 3.8 18.8 24.7 20.9 8.1 20.2 29.5 16.3 24.3 16.4 13.9 1.8 42.9 27.0 4.4 1.4 15.1 26.7 5.1 10.7 45.7 50.1 36.7 10.7 12.9 26.9 38.3 32.1 15.1 22.1 29.5 30.6 41.4 9.8 3.2 17.7 10.2 10.6 9.7 9.3 20.1 20.5 23.2 5.5 13.5 15.5 17.7 24.9 29.1 44.8 48.4 11.1 34.9 18.8 0.0 5.9 0.0 0.7 8.0 0.2 1.7 1.4 1.4 4.6 0.5 0.1 0.3 1.0 0.6 4.8 1.9 2.9 2.1 2.6 2.9 9.1 3.1 3.1 4.0 5.4 4.4 5.8 4.1 4.8 4.7 5.9 0.0 1.5 0.0 2.4 1.8 0.4 1.2 1.2 0.3 0.8 0.6 1.5 0.0 0.9 0.0 0.0 0.8 3.7 4.9 0.0 1.0 29.5 1.5 1.5 8.4 0.0 0.4 0.1 0.8 3.8 1.8 0.5 0.7 0.0 0.3 7.1 0.4 9.4 0.0 0.2 3.6 0.0 18.2 5.8 30.2 0.0 6.9 3.6 0.0 9.6 0.6 2.1 0.0 0.1 0.6 0.0 0.0 1.6 0.4 1.3 0.3 2.1 0.2 0.0 0.9 2.2 28.0 4.1 2.0 1.0 0.7 1.4 0.8 1.6 0.8 FAM72B RP11-439A17.6 ENSG00000188610 "Family with sequence similarity 72 member B" Q86X60 1 121167646-121185539 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.2;lymphoid tissue: 10.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 7.3;Early spermatids: 11.3;Erythroid cells: 5.9;Hepatic stellate cells: 6.4;Spermatocytes: 17.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA043271, HPA067321" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "Plasma membrane, Cytosol" "HPA043271: AB_2678402, HPA067321: " "unprognostic (8.53e-2)" "unprognostic (1.97e-2)" "unprognostic (1.63e-3)" "unprognostic (1.25e-3)" "unprognostic (4.36e-1)" "unprognostic (1.05e-1)" "unprognostic (1.26e-4)" "unprognostic (8.22e-5)" "unprognostic (1.30e-2)" "unprognostic (1.79e-2)" "unprognostic (1.36e-4)" "unprognostic (2.46e-2)" "unprognostic (0.00e+0)" "unprognostic (2.39e-2)" "unprognostic (1.71e-1)" "unprognostic (1.17e-2)" "unprognostic (5.30e-2)" 0.8 0.6 1.2 3.7 1.0 6.2 0.8 2.0 1.1 0.5 1.3 1.1 1.3 0.5 0.4 1.6 0.4 1.0 0.3 1.2 1.2 0.4 0.4 0.6 8.1 1.6 1.4 0.4 0.2 0.7 0.2 1.4 1.6 0.2 1.2 0.1 0.4 0.2 0.1 1.9 1.1 0.7 1.3 2.0 1.0 2.3 1.3 10.3 0.3 0.2 6.6 0.8 0.7 1.4 28.6 10.3 16.5 8.2 1.6 2.4 13.3 14.7 6.2 16.8 14.1 0.1 14.5 62.9 19.9 2.7 16.4 17.1 23.1 8.3 25.9 41.1 17.3 27.2 12.0 12.5 1.0 47.7 23.2 1.3 0.9 13.0 26.5 4.2 10.3 51.0 36.1 37.3 12.4 12.1 24.1 39.1 31.6 14.9 20.6 35.8 35.8 28.7 6.7 3.2 18.0 10.4 11.1 8.6 8.6 16.9 11.4 36.5 3.6 13.8 23.5 27.3 26.6 32.6 44.1 61.3 12.4 50.8 32.6 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.4 0.3 1.2 1.0 2.0 1.1 1.2 1.2 1.6 1.4 1.6 1.3 1.3 1.4 1.3 0.0 0.0 0.0 1.6 1.0 0.1 0.2 0.0 0.0 0.3 0.6 0.4 0.0 0.1 0.0 0.0 0.8 0.1 7.3 0.0 0.2 11.3 0.2 0.4 2.5 0.0 5.9 0.1 0.2 2.3 0.6 1.1 0.2 0.0 0.5 6.4 0.0 1.1 0.0 0.3 4.9 0.0 1.9 2.8 3.0 0.6 1.6 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.1 2.3 0.0 2.5 0.0 2.1 0.0 0.7 0.0 0.0 0.3 0.9 17.0 3.1 3.5 1.0 0.1 1.2 0.2 3.6 0.0 FAM72C RP5-998N21.9 ENSG00000263513 "Family with sequence similarity 72 member C" H0Y354 1 143955364-143971965 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.9;lymphoid tissue: 5.4" "Cell type enhanced" "Detected in some" "Erythroid cells: 7.8;Extravillous trophoblasts: 4.5;Sertoli cells: 6.6;Spermatocytes: 9.4;Spermatogonia: 3.5" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/84: 64.9" "HPA043271, HPA067321" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "Plasma membrane, Cytosol" "HPA043271: AB_2678402, HPA067321: " "unprognostic (2.18e-1)" "unprognostic (1.50e-1)" "unprognostic (6.45e-3)" "unprognostic (2.69e-2)" "unprognostic (2.21e-1)" "unprognostic (3.98e-3)" "unprognostic (9.46e-5)" "unprognostic (1.23e-3)" "unprognostic (4.36e-1)" "unprognostic (7.26e-2)" "unprognostic (1.04e-2)" "unprognostic (1.95e-1)" "unprognostic (0.00e+0)" "unprognostic (2.95e-1)" "unprognostic (4.70e-2)" "unprognostic (5.82e-2)" "unprognostic (1.47e-2)" 0.4 0.2 0.1 1.5 0.1 2.9 0.3 0.2 0.2 0.2 0.0 0.4 0.6 0.2 0.0 1.3 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.3 4.5 0.1 0.1 0.1 0.2 0.0 0.0 0.5 0.1 0.1 0.6 0.0 0.2 0.0 0.0 1.2 0.4 0.3 0.1 1.2 0.3 1.6 0.1 5.4 0.1 0.1 4.5 0.4 0.4 0.2 18.7 10.6 12.5 5.7 0.6 1.7 12.1 8.9 2.8 12.0 9.0 1.6 21.7 44.4 11.6 1.0 11.0 17.4 17.2 5.5 13.0 15.3 10.0 19.1 9.4 3.3 0.4 39.5 16.6 0.3 0.1 9.1 24.3 2.5 5.1 34.7 34.0 20.5 0.8 1.4 23.2 30.4 10.2 20.8 6.6 29.7 9.0 31.5 2.1 2.3 6.3 11.5 8.7 5.0 4.9 13.0 12.5 33.4 3.7 9.4 15.4 12.5 20.3 41.9 64.9 26.0 5.1 24.1 6.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.8 0.0 0.0 0.0 0.5 0.1 0.1 0.3 0.6 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 2.3 0.3 0.2 1.3 0.0 7.8 0.2 0.2 4.5 0.3 0.0 0.1 0.0 0.5 1.8 0.1 1.7 0.0 0.3 0.6 0.0 2.2 1.4 0.5 0.3 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 6.6 0.3 0.7 9.4 3.5 1.3 0.3 0.3 0.7 0.3 0.5 0.0 FAM72D ENSG00000215784 "Family with sequence similarity 72 member D" Q6L9T8 1 145095974-145112696 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.0;lymphoid tissue: 6.7" "Group enriched" "Detected in some" 4 "Early spermatids: 7.3;Erythroid cells: 9.7;Extravillous trophoblasts: 5.5;Spermatocytes: 15.4;Spermatogonia: 4.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA043271, HPA067321" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "Plasma membrane, Cytosol" "HPA043271: AB_2678402, HPA067321: " "unprognostic (2.70e-2)" "unprognostic (1.64e-1)" "unprognostic (1.73e-1)" "unprognostic (4.03e-3)" "unprognostic (1.26e-1)" "unprognostic (7.10e-3)" "unprognostic (5.88e-5)" "unprognostic (7.65e-4)" "unprognostic (6.72e-2)" "unprognostic (2.36e-2)" "unprognostic (1.22e-2)" "unprognostic (1.46e-1)" "unprognostic (0.00e+0)" "unprognostic (6.63e-2)" "unprognostic (1.72e-1)" "unprognostic (9.74e-2)" "unprognostic (6.50e-2)" 0.7 0.3 0.4 3.0 0.4 4.0 0.5 0.7 0.5 0.3 0.2 0.8 1.0 0.3 0.1 1.1 0.2 0.5 0.2 0.4 0.8 0.2 0.3 0.5 4.8 0.6 0.7 0.2 0.1 0.2 0.1 1.1 0.6 0.1 1.0 0.1 0.2 0.1 0.0 1.9 1.3 0.5 0.4 1.2 0.6 2.1 0.7 6.7 0.2 0.1 4.5 0.6 0.4 0.5 16.6 10.4 11.7 4.5 0.5 1.0 12.4 9.8 3.0 11.1 7.1 7.5 14.7 26.6 9.3 1.5 11.1 17.3 13.6 3.0 12.8 22.6 14.1 13.6 5.8 9.7 0.6 24.0 14.2 0.8 1.1 9.4 16.9 2.0 5.6 33.0 26.8 34.9 7.2 12.4 16.6 22.5 21.1 20.3 14.4 13.9 14.3 30.7 4.0 2.2 10.9 9.1 7.3 6.3 4.4 13.9 17.2 15.7 2.7 8.3 9.6 7.3 16.7 27.0 46.5 39.3 0.2 18.7 10.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.4 0.4 0.7 0.5 0.4 0.8 0.6 0.7 0.6 0.4 0.7 0.5 2.0 0.0 0.0 0.0 0.8 1.0 0.0 0.2 1.2 0.0 0.2 0.4 1.1 0.0 0.2 0.0 0.0 1.2 0.1 0.8 0.0 0.1 7.3 0.2 0.3 2.1 0.0 9.7 0.3 0.0 5.5 0.8 0.0 0.2 0.0 0.3 0.4 0.1 1.5 0.0 0.5 0.8 0.0 1.0 1.0 0.6 0.0 1.8 1.8 1.0 0.8 0.0 0.0 1.0 0.1 0.1 0.1 0.0 0.8 0.2 0.3 0.1 0.3 0.0 0.0 0.5 0.8 15.4 4.5 1.6 1.0 0.3 0.4 0.1 1.4 0.1 FAM78A "C9orf59, FLJ00024" ENSG00000126882 "Family with sequence similarity 78 member A" Q5JUQ0 9 131258076-131276510 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 53.7;testis: 31.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 55.7;Early spermatids: 90.6;Granulosa cells: 167.2;Late spermatids: 120.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 39.3;HEL: 38.6;HL-60: 38.7;NB-4: 60.7;THP-1: 53.5;U-937: 35.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021472, HPA023914" Uncertain Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 23: Testis - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Vesicles" "HPA021472: AB_1848411, HPA023914: AB_1848412" "unprognostic (5.16e-2)" "prognostic favorable (3.67e-4)" "unprognostic (3.65e-2)" "unprognostic (2.07e-2)" "unprognostic (2.71e-1)" "prognostic favorable (2.00e-4)" "unprognostic (3.24e-1)" "unprognostic (5.49e-2)" "unprognostic (1.46e-2)" "unprognostic (5.83e-1)" "unprognostic (5.84e-2)" "unprognostic (6.79e-2)" "unprognostic (1.59e-3)" "unprognostic (2.61e-3)" "unprognostic (7.42e-2)" "unprognostic (2.61e-2)" "unprognostic (2.39e-1)" 2.9 2.0 3.8 13.8 5.6 21.7 1.7 3.6 6.3 1.4 1.8 2.4 2.7 1.5 0.3 1.7 1.3 3.1 26.5 5.1 3.7 1.6 1.5 6.1 24.5 5.6 4.1 1.4 1.1 1.1 1.2 5.3 4.9 1.4 1.6 4.6 2.7 0.9 53.7 1.2 8.9 1.8 4.6 21.6 3.8 31.9 5.8 21.1 1.6 20.2 14.9 3.5 1.1 5.7 0.7 0.3 2.5 5.6 1.7 0.5 39.3 0.3 0.3 0.5 0.2 0.3 0.2 17.1 0.2 0.3 0.8 0.1 16.0 0.2 0.1 4.4 1.4 38.6 0.6 0.3 0.6 38.7 1.5 0.4 0.8 0.0 0.1 0.5 22.2 10.8 13.8 4.7 0.5 6.0 1.7 60.7 2.6 0.3 0.6 4.0 2.3 23.7 0.2 0.1 1.5 2.1 2.3 0.8 2.4 0.9 1.4 53.5 0.6 2.3 2.4 1.3 0.1 3.4 1.9 9.7 0.3 35.9 0.6 0.5 9.7 17.6 9.2 12.6 7.4 14.2 8.9 10.1 6.0 15.9 11.0 9.3 9.8 3.1 9.9 2.7 9.5 8.7 3.8 5.6 3.6 6.3 5.1 3.7 5.6 4.1 4.9 4.6 5.8 5.7 3.2 0.0 1.5 0.0 15.5 0.9 0.0 0.0 0.0 55.7 0.4 0.5 17.6 0.0 0.0 1.8 0.0 1.1 19.0 0.0 0.0 0.1 90.6 0.1 0.2 6.8 0.0 3.4 5.0 0.0 37.6 3.1 0.5 0.1 1.3 167.2 6.4 0.5 25.7 0.0 1.7 0.0 0.0 21.7 10.6 120.3 5.0 14.8 1.8 15.9 15.6 0.8 30.9 1.0 0.1 0.1 0.0 3.4 12.0 0.0 0.0 0.2 0.0 1.8 0.0 0.6 6.3 2.2 1.2 0.0 0.9 1.4 17.4 1.0 0.0 0.1 FAM78B ENSG00000188859 "Family with sequence similarity 78 member B" Q5VT40 1 166057426-166167001 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 2.6" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 87.6;Excitatory neurons: 55.4;Horizontal cells: 82.4;Inhibitory neurons: 85.0;Oligodendrocyte precursor cells: 45.8" "Cancer enhanced" "Detected in many" "melanoma: 3.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HDLM-2: 8.6;RT4: 4.9;SK-MEL-30: 10.1;U-2 OS: 2.6;WM-115: 3.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052789, HPA073246" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus, Vesicles" "HPA052789: AB_2681949, HPA073246: AB_2686588" "unprognostic (7.38e-3)" "unprognostic (1.14e-3)" "unprognostic (7.96e-2)" "unprognostic (3.16e-2)" "unprognostic (3.77e-2)" "unprognostic (3.34e-1)" "unprognostic (1.26e-2)" "unprognostic (1.22e-1)" "unprognostic (8.16e-3)" "unprognostic (3.25e-2)" "unprognostic (1.69e-3)" "unprognostic (3.87e-2)" "unprognostic (1.87e-11)" "unprognostic (7.41e-2)" "unprognostic (2.09e-1)" "unprognostic (5.41e-2)" "unprognostic (2.69e-2)" 0.7 0.2 0.9 0.0 0.7 0.0 0.5 0.5 2.6 1.1 0.0 0.5 0.2 0.7 0.0 0.4 0.2 0.1 0.6 1.0 0.1 0.2 0.7 0.2 0.1 0.6 0.1 0.3 0.4 0.1 0.5 0.0 0.1 0.4 0.1 0.8 0.3 0.1 0.7 0.5 0.1 0.2 0.2 0.2 0.2 0.7 0.1 0.0 0.4 0.1 0.1 0.8 0.5 0.5 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 8.6 0.0 0.0 0.1 0.3 0.2 0.0 0.4 0.0 0.3 0.0 0.3 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 4.9 0.8 0.5 0.0 0.1 10.1 0.0 0.3 0.2 0.1 0.6 2.6 0.0 0.1 0.0 0.0 0.0 0.5 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.5 2.6 1.0 0.1 0.6 0.1 0.1 0.2 0.1 0.5 1.2 0.0 1.7 5.5 0.4 0.5 0.5 0.0 1.8 15.5 1.0 0.8 9.9 2.8 0.0 0.0 87.6 0.0 0.0 0.4 1.9 0.7 2.5 0.1 1.7 1.6 0.0 0.0 55.4 0.2 0.0 1.6 0.0 0.1 0.0 1.1 0.4 1.6 0.0 82.4 85.0 0.6 0.0 0.3 0.6 2.6 1.2 0.1 1.8 5.6 0.6 2.2 0.0 45.8 5.7 0.3 0.3 0.7 0.0 0.2 0.1 1.3 0.0 12.9 0.0 4.5 1.0 0.6 4.4 0.6 0.1 0.0 0.7 0.4 1.1 0.2 FAM83E FLJ20200 ENSG00000105523 "Family with sequence similarity 83 member E" Q2M2I3 19 48599961-48615076 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.7;salivary gland: 28.5;stomach 1: 37.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 22.8;Early spermatids: 26.0;Gastric mucus-secreting cells: 74.9;Intestinal goblet cells: 26.9;Paneth cells: 16.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "CAPAN-2: 2.9;OE19: 9.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049305, HPA075968" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Cytosol Vesicles "HPA049305: AB_2680705, HPA075968: " "unprognostic (1.36e-1)" "unprognostic (9.81e-3)" "unprognostic (3.83e-2)" "unprognostic (7.39e-2)" "unprognostic (4.77e-2)" "unprognostic (4.56e-3)" "unprognostic (1.36e-1)" "unprognostic (2.26e-2)" "unprognostic (3.18e-1)" "unprognostic (2.71e-1)" "unprognostic (8.00e-2)" "unprognostic (9.31e-2)" "unprognostic (7.05e-8)" "unprognostic (5.17e-2)" "unprognostic (3.69e-1)" "unprognostic (3.70e-1)" "unprognostic (8.90e-3)" 0.1 0.1 0.2 3.7 0.3 0.4 1.4 0.8 0.5 10.6 0.2 32.7 30.0 1.1 0.1 7.0 3.9 6.4 0.2 0.3 0.2 0.8 0.3 8.0 0.2 0.1 0.1 0.0 1.2 0.0 0.2 0.6 0.2 3.2 16.6 0.2 28.5 0.4 2.7 1.9 30.0 1.0 0.0 0.2 37.4 2.2 0.2 0.1 0.1 0.0 1.3 1.2 4.1 0.5 0.4 0.4 0.0 0.7 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.3 2.9 0.5 0.2 0.1 0.0 0.5 0.1 0.0 0.0 0.4 0.1 0.1 0.3 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.6 0.1 0.8 1.1 9.4 0.9 0.2 0.1 0.3 0.0 0.2 0.5 0.2 0.0 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.4 0.2 0.0 0.2 0.5 0.1 0.1 0.2 0.1 1.0 0.1 0.2 0.1 0.1 0.0 0.4 0.0 0.1 0.0 0.1 0.1 0.2 0.6 0.1 0.1 0.1 0.0 0.0 0.2 0.3 0.8 0.5 0.3 0.2 0.1 0.1 0.2 0.0 0.2 0.5 0.0 9.6 13.4 1.3 0.4 0.0 1.4 0.8 0.6 0.0 1.8 0.8 2.1 8.6 6.5 1.8 0.0 0.1 0.3 22.8 0.0 0.1 26.0 4.8 0.5 0.2 5.4 0.0 0.3 1.1 0.1 0.2 74.9 5.4 0.0 0.0 0.0 0.1 0.0 0.0 0.4 26.9 2.0 0.0 0.0 9.3 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.5 0.3 1.6 16.5 0.0 0.4 3.3 12.7 0.0 5.1 0.0 0.0 0.2 0.2 0.8 0.5 2.3 0.0 0.1 0.3 0.1 12.8 6.9 FAM86B1 MGC16279 ENSG00000186523 "Family with sequence similarity 86 member B1" Q8N7N1 8 12182096-12194133 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 5.4;pituitary gland: 6.4" "Cell type enhanced" "Detected in many" "Granulosa cells: 17.5;Proximal tubular cells: 10.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 5.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 2.5" "HPA041610, HPA055718" Uncertain Uncertain Vesicles NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA041610: AB_2677581, HPA055718: AB_2682895" "unprognostic (1.90e-2)" "unprognostic (8.67e-2)" "unprognostic (2.79e-1)" "unprognostic (3.74e-2)" "unprognostic (3.13e-3)" "unprognostic (1.05e-1)" "unprognostic (1.94e-1)" "unprognostic (1.74e-1)" "unprognostic (5.68e-2)" "unprognostic (1.91e-2)" "unprognostic (1.32e-1)" "unprognostic (6.69e-2)" "unprognostic (8.00e-3)" "unprognostic (2.66e-2)" "unprognostic (1.58e-1)" "unprognostic (7.02e-2)" "unprognostic (2.58e-2)" 0.5 0.7 0.9 0.4 2.2 0.5 1.0 0.2 5.4 2.2 0.0 1.4 0.8 2.3 0.4 0.6 2.4 0.5 0.9 2.6 0.1 1.1 0.3 0.8 0.3 2.0 0.0 3.7 0.9 0.4 6.4 0.1 0.1 2.4 0.0 1.7 0.8 0.3 0.8 1.0 0.6 0.1 0.0 0.6 0.7 0.5 0.5 0.1 1.3 0.0 0.0 1.2 1.5 0.0 0.2 1.2 0.0 2.5 0.0 0.4 1.0 2.0 0.2 0.6 0.3 0.7 0.5 0.5 0.1 0.1 0.7 2.2 0.4 0.7 0.2 0.2 0.3 0.1 0.3 0.3 1.1 0.9 0.9 0.1 0.2 0.2 1.7 0.4 0.1 0.9 0.8 0.7 0.0 1.1 0.0 0.6 0.8 0.7 0.2 0.7 0.5 0.1 0.1 0.6 2.1 0.4 0.2 0.2 0.3 0.2 1.0 0.0 0.0 0.4 0.4 1.8 0.5 0.2 0.6 0.3 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.2 0.2 5.4 2.6 0.1 2.0 0.0 0.1 0.0 0.5 0.0 1.2 3.2 1.8 0.7 0.9 1.1 3.1 1.0 3.4 2.1 4.7 5.0 0.5 8.6 3.0 1.8 2.1 1.5 0.4 0.8 5.9 5.1 5.8 4.7 2.3 1.6 4.2 1.3 0.3 1.8 1.6 2.6 1.5 1.5 1.3 17.5 2.5 1.3 1.9 1.7 0.3 1.5 0.0 1.3 0.6 6.2 1.8 0.7 3.6 0.0 0.1 2.7 4.1 0.0 0.1 3.5 0.3 2.6 0.1 7.0 0.8 10.3 8.5 1.7 0.0 3.3 2.1 0.9 0.8 3.8 1.3 1.1 0.8 2.3 2.4 1.8 FAM86B2 ENSG00000145002 "Family with sequence similarity 86 member B2" P0C5J1 8 12425614-12436343 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 3.2;Early spermatids: 1.6;Granulosa cells: 2.7;Late spermatids: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "hTERT-HME1: 5.3;RPMI-8226: 12.5" "HPA041610, HPA055718" Uncertain Uncertain Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA041610: AB_2677581, HPA055718: AB_2682895" "unprognostic (3.75e-2)" "unprognostic (1.87e-1)" "unprognostic (6.57e-2)" "unprognostic (1.01e-1)" "unprognostic (3.26e-2)" "unprognostic (2.48e-1)" "unprognostic (2.26e-1)" "unprognostic (1.48e-1)" "unprognostic (3.82e-1)" "unprognostic (3.24e-1)" "unprognostic (6.04e-4)" "unprognostic (9.37e-2)" "unprognostic (3.78e-2)" "unprognostic (2.31e-2)" "unprognostic (2.62e-1)" "unprognostic (1.37e-1)" "unprognostic (2.13e-2)" 0.3 0.4 0.1 0.1 0.2 0.0 0.4 0.1 0.3 0.6 0.1 0.3 0.1 0.5 0.0 0.9 1.4 0.1 0.1 0.2 0.2 0.5 0.3 0.3 0.0 0.2 0.3 0.6 0.6 0.4 1.0 0.0 0.1 0.4 0.1 0.1 0.3 0.4 0.1 0.3 0.1 0.1 0.0 0.1 0.3 0.2 0.2 0.0 0.9 0.0 0.0 0.4 0.4 0.1 0.2 0.6 0.1 0.0 0.2 1.1 1.3 0.2 0.6 0.4 1.0 0.4 1.1 0.7 0.0 1.2 0.3 0.2 0.9 1.5 0.0 0.0 0.0 0.2 0.9 0.0 1.0 0.0 0.0 0.3 1.3 1.3 5.3 0.0 0.0 0.0 1.1 0.2 0.0 0.3 0.0 0.3 1.0 1.9 0.4 0.1 0.1 12.5 0.0 0.9 1.6 0.0 0.4 1.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.1 0.2 0.1 0.3 0.2 0.2 0.2 0.3 0.1 0.0 0.2 0.1 0.1 3.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.3 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 2.7 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.0 FAM89A "C1orf153, MGC15887" ENSG00000182118 "Family with sequence similarity 89 member A" Q96GI7 1 231018958-231040254 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 60.0;placenta: 68.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 186.3;Extravillous trophoblasts: 267.5;Rod photoreceptor cells: 102.5;Syncytiotrophoblasts: 278.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 145.4;SK-MEL-30: 81.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA059052, HPA059578" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus, Vesicles" Nucleoplasm "HPA059052: AB_2683890, HPA059578: AB_2684070" "unprognostic (7.80e-2)" "unprognostic (1.20e-1)" "unprognostic (3.58e-3)" "unprognostic (1.32e-2)" "unprognostic (2.77e-1)" "unprognostic (1.41e-2)" "unprognostic (1.98e-2)" "unprognostic (1.10e-1)" "unprognostic (8.05e-3)" "unprognostic (4.85e-1)" "unprognostic (1.54e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (1.75e-5)" "unprognostic (2.87e-2)" "unprognostic (2.03e-1)" "unprognostic (2.01e-1)" "unprognostic (9.26e-2)" 60.0 18.0 16.0 4.8 15.3 5.9 36.5 20.7 16.4 11.0 21.3 4.4 1.7 7.5 1.6 6.5 7.1 5.9 10.6 14.2 23.4 22.2 9.2 19.2 5.9 22.6 21.4 6.0 10.6 6.0 5.8 68.2 20.9 7.1 2.7 17.3 5.3 4.6 5.9 30.6 4.6 4.1 21.2 17.5 7.6 3.0 25.1 2.9 5.5 6.7 4.7 8.9 9.2 19.5 0.9 13.7 6.3 13.4 15.0 3.0 145.4 7.8 5.8 2.8 5.1 21.1 12.1 0.0 1.8 5.1 16.7 8.4 12.0 1.9 2.3 42.4 28.9 6.7 0.3 0.9 57.6 5.0 35.2 50.1 26.6 0.0 13.2 0.1 7.4 15.0 53.4 8.6 2.7 5.0 3.2 8.8 9.4 12.6 4.3 16.6 20.3 16.0 10.1 14.8 5.8 16.1 2.6 1.2 81.6 13.9 0.8 29.2 1.1 22.5 0.1 0.4 14.7 18.3 23.7 11.6 6.7 9.8 45.7 1.4 0.2 0.0 0.2 0.0 0.3 0.3 0.2 0.5 0.0 0.1 0.4 0.9 0.0 0.1 0.0 0.0 0.0 0.2 16.0 15.3 20.7 16.4 14.2 23.4 22.6 21.4 20.9 21.2 25.1 19.5 82.3 0.0 2.6 3.6 4.2 30.1 22.0 0.3 8.0 48.1 3.8 5.2 3.3 7.2 0.7 0.0 77.2 186.3 4.9 0.3 3.9 2.8 1.3 1.3 39.3 44.5 0.0 14.9 1.1 3.3 267.5 11.6 0.5 2.6 4.5 0.5 10.8 11.1 51.0 8.4 10.8 0.6 0.0 19.6 2.1 3.6 2.8 8.5 21.4 22.5 0.5 26.2 1.0 10.1 2.0 4.4 0.5 1.5 1.4 30.2 0.0 5.1 0.1 102.5 0.0 9.9 8.5 4.2 11.6 1.7 32.8 278.3 5.5 0.4 1.3 15.4 FAM98A DKFZP564F0522 ENSG00000119812 "Family with sequence similarity 98 member A" Q8NCA5 2 33583660-33599382 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036250, HPA036251" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 52: Non-specific - Transcription" Vesicles "HPA036250: AB_2675020, HPA036251: AB_10673124" "unprognostic (7.25e-2)" "unprognostic (9.92e-2)" "unprognostic (1.59e-2)" "unprognostic (1.40e-1)" "unprognostic (1.51e-1)" "unprognostic (2.42e-2)" "prognostic unfavorable (4.86e-7)" "unprognostic (1.07e-1)" "unprognostic (2.29e-1)" "unprognostic (2.78e-2)" "unprognostic (1.01e-1)" "unprognostic (3.51e-1)" "unprognostic (2.02e-2)" "unprognostic (2.38e-2)" "unprognostic (2.66e-1)" "prognostic unfavorable (8.18e-5)" "unprognostic (6.01e-2)" 29.2 21.5 21.4 20.5 26.5 7.2 16.3 28.6 30.4 21.7 27.9 20.7 13.6 19.1 19.3 19.9 12.2 15.7 40.6 30.8 25.7 27.4 25.5 11.5 18.4 25.1 24.5 16.5 14.6 51.2 20.5 20.6 29.5 23.0 17.1 17.2 28.0 16.7 61.3 14.9 12.1 36.4 27.7 14.3 19.8 49.4 26.4 17.4 19.2 62.4 22.6 27.5 12.9 39.7 93.4 47.2 25.5 43.9 99.4 108.3 41.9 224.1 81.6 62.3 80.2 49.8 18.8 144.5 41.3 101.8 55.3 41.3 84.8 60.8 84.2 67.7 56.3 119.7 46.9 69.3 47.2 95.5 44.7 56.1 42.2 83.9 52.1 63.5 83.3 15.5 84.4 43.8 108.7 46.1 53.3 28.5 64.4 83.2 59.9 41.1 82.5 51.9 65.0 72.2 45.6 26.1 60.0 89.5 27.0 40.7 36.2 15.6 135.7 39.5 66.1 82.9 89.2 80.2 106.6 142.4 91.2 68.2 56.8 1.3 4.1 2.3 6.4 7.2 6.9 10.7 5.4 5.8 6.1 5.5 6.9 5.7 0.1 4.0 4.6 3.5 9.0 4.1 21.4 26.5 28.6 30.4 30.8 25.7 25.1 24.5 29.5 27.7 26.4 39.7 19.0 22.4 11.5 6.8 17.4 20.4 19.0 12.2 18.8 16.8 15.0 14.0 74.6 11.5 19.8 7.3 2.1 25.5 9.8 6.9 25.4 20.3 14.9 16.7 29.9 21.1 5.4 12.8 22.8 29.2 33.2 31.9 17.9 18.9 2.5 44.4 17.2 23.4 16.4 47.1 15.7 15.1 8.2 7.7 11.8 13.8 22.4 8.7 8.8 6.5 5.9 17.4 16.5 9.0 36.1 26.0 8.7 21.8 40.3 22.6 9.3 46.2 16.5 15.7 0.0 21.7 27.1 41.5 40.1 26.1 20.5 40.0 13.7 54.9 12.1 23.4 FAM98B FLJ38426 ENSG00000171262 "Family with sequence similarity 98 member B" Q52LJ0 15 38454127-38487710 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008320, HPA008502" Enhanced Supported Nucleoplasm,Vesicles NA NA 20000 "Cluster 40: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Vesicles" "HPA008320: AB_1848419, HPA008502: AB_1848420" "unprognostic (1.05e-2)" "unprognostic (3.13e-1)" "unprognostic (1.15e-1)" "unprognostic (1.00e-2)" "unprognostic (1.54e-2)" "unprognostic (3.09e-2)" "unprognostic (9.25e-3)" "unprognostic (1.74e-1)" "unprognostic (4.69e-2)" "unprognostic (2.18e-1)" "unprognostic (3.15e-1)" "unprognostic (3.15e-2)" "unprognostic (1.51e-2)" "unprognostic (2.26e-1)" "unprognostic (4.36e-2)" "unprognostic (1.94e-1)" "unprognostic (1.13e-1)" 12.7 11.4 9.5 12.8 10.2 9.8 12.9 16.4 12.6 9.7 7.2 15.4 9.6 13.3 9.0 9.0 8.1 7.0 12.4 10.8 10.9 13.1 7.8 8.1 13.8 9.4 9.7 11.2 6.1 19.3 6.4 12.0 10.0 12.1 11.6 19.8 6.3 10.0 13.8 8.8 10.0 9.5 10.1 11.2 9.5 8.5 9.6 28.6 11.7 16.3 13.3 11.9 7.0 12.6 30.7 16.2 77.7 40.0 14.1 25.7 37.9 38.6 28.2 37.4 37.5 35.8 14.4 21.1 41.4 32.2 37.9 31.8 47.4 39.5 52.2 21.8 25.7 62.6 33.9 27.8 20.4 59.8 34.6 23.9 24.1 33.3 38.5 27.4 38.9 45.7 45.6 25.7 36.0 13.8 50.7 31.8 42.0 34.8 22.3 53.3 42.0 17.7 32.8 39.9 47.8 48.9 42.5 27.0 19.8 34.6 33.0 36.6 32.7 42.1 51.5 28.2 44.0 47.6 46.1 78.3 23.1 38.9 44.8 2.3 0.5 1.4 2.8 0.4 2.4 1.6 2.8 2.3 0.6 1.9 3.4 2.6 0.4 2.2 0.6 1.4 1.9 0.4 9.5 10.2 16.4 12.6 10.8 10.9 9.4 9.7 10.0 10.1 9.6 12.6 17.9 16.0 21.4 16.3 16.8 14.7 12.7 14.1 14.2 36.8 15.2 11.6 48.9 12.8 18.1 16.5 16.7 30.6 16.4 11.0 7.9 16.4 3.4 19.1 21.5 16.9 12.6 16.6 22.5 19.8 22.4 16.6 16.8 17.0 13.3 18.4 16.8 13.1 12.6 20.2 20.5 22.6 12.2 15.8 12.2 2.5 12.5 10.9 5.4 18.7 21.4 18.5 21.6 12.1 23.8 14.3 9.8 17.0 18.2 12.4 11.1 12.7 18.8 27.9 6.6 21.5 16.2 27.2 17.1 19.7 14.8 21.5 15.3 14.7 19.3 14.1 FANCD2OS "C3orf24, MGC40179" ENSG00000163705 "FANCD2 opposite strand" Q96PS1 3 10081317-10108255 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 33 "testis: 61.6" "Group enriched" "Detected in some" 59 "Early spermatids: 565.0;Late spermatids: 852.8" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebellum: 1.8" "Immune cell enriched" "Detected in some" 5 "neutrophil: 5.4" "Lineage enriched" "Detected in many" 5 "granulocytes: 5.4" "Cell line enhanced" "Detected in some" "CACO-2: 1.3;MCF7: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA076166 Approved Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 74: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA076166: " "unprognostic (5.99e-2)" "unprognostic (4.33e-3)" "unprognostic (8.04e-2)" "unprognostic (1.11e-3)" "unprognostic (3.51e-1)" "unprognostic (2.63e-2)" "unprognostic (4.78e-2)" "unprognostic (3.49e-1)" "unprognostic (2.53e-3)" "unprognostic (3.91e-2)" "unprognostic (9.45e-2)" "unprognostic (2.11e-7)" "unprognostic (2.95e-1)" "unprognostic (1.23e-1)" "unprognostic (2.15e-1)" "unprognostic (1.80e-1)" 0.0 0.0 0.3 0.0 0.1 1.0 0.0 1.8 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 61.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.4 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.5 0.4 0.3 0.2 0.4 0.3 0.3 0.4 0.2 0.1 0.8 0.3 0.3 5.4 0.2 1.0 0.3 0.1 0.1 0.3 0.1 1.8 0.4 0.2 0.1 0.3 0.2 0.3 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 565.0 0.4 0.0 0.3 0.0 0.0 0.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 852.8 7.2 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.9 0.0 4.1 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 12.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FANCL "FAAP43, FLJ10335, PHF9, Pog" ENSG00000115392 "FA complementation group L" Q9NW38 2 58159243-58241372 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 81.4;Oligodendrocytes: 188.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033842, HPA036685, HPA036686" Supported Approved "Nuclear bodies,Vesicles" NA Yes "Cluster 19: B-cells - Humoral immune response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear bodies" Vesicles "CAB033842: AB_1122766, HPA036685: AB_10672474, HPA036686: AB_10670844" "unprognostic (3.02e-1)" "unprognostic (5.52e-2)" "unprognostic (2.19e-1)" "unprognostic (2.02e-3)" "unprognostic (6.24e-2)" "unprognostic (2.92e-2)" "prognostic unfavorable (2.81e-7)" "unprognostic (4.71e-2)" "unprognostic (2.63e-2)" "unprognostic (1.31e-2)" "unprognostic (3.50e-1)" "unprognostic (1.17e-2)" "prognostic unfavorable (1.12e-7)" "unprognostic (1.50e-1)" "unprognostic (1.39e-1)" "unprognostic (9.08e-3)" "prognostic favorable (7.80e-5)" 8.5 35.3 39.4 11.0 49.5 15.1 19.5 35.3 39.4 18.6 27.2 12.1 11.5 19.9 18.4 11.5 13.9 12.0 13.0 34.1 45.1 12.2 21.7 9.6 14.8 51.6 40.3 24.8 14.5 14.0 44.3 12.5 55.4 14.7 14.8 24.6 18.7 10.7 9.1 17.9 12.8 13.5 40.9 16.8 13.1 19.1 41.2 13.2 17.1 9.1 12.6 11.7 14.6 68.6 48.6 35.0 69.4 34.0 11.9 15.1 36.9 34.8 21.5 33.8 43.5 30.9 59.4 33.4 43.8 11.4 46.3 27.5 39.0 26.4 56.0 78.8 61.7 54.8 49.5 42.1 13.0 53.3 29.0 11.8 12.4 24.8 9.7 29.9 27.0 23.5 51.9 29.6 23.2 24.6 18.9 65.8 75.2 77.4 7.2 35.2 52.5 26.1 29.9 47.2 78.1 39.3 49.5 20.2 33.8 37.0 18.7 35.4 15.9 30.0 45.0 22.3 39.0 30.4 20.6 19.7 63.7 35.7 46.6 3.2 3.0 4.9 3.7 5.6 3.0 9.1 3.2 4.2 5.9 9.3 1.0 2.3 0.8 7.6 4.3 5.3 4.8 2.2 39.4 49.5 35.3 39.4 34.1 45.1 51.6 40.3 55.4 40.9 41.2 68.6 16.7 19.2 20.0 18.6 9.4 10.3 13.9 26.1 11.4 16.6 12.5 15.4 16.4 8.6 16.1 9.2 4.2 29.1 4.8 7.2 11.7 9.7 2.5 11.1 15.8 14.8 9.0 14.5 45.0 4.2 14.0 12.2 15.3 6.2 10.8 25.8 13.2 12.5 10.9 8.4 38.4 15.0 30.5 6.3 4.6 3.6 10.8 7.0 26.6 34.7 6.8 22.8 3.1 81.4 188.9 4.6 13.3 14.3 9.7 6.2 21.7 5.7 23.2 18.7 13.1 10.8 12.4 52.6 37.9 9.5 6.8 7.4 5.6 13.2 16.0 9.3 FBXL6 FBL6 ENSG00000182325 "F-box and leucine rich repeat protein 6" Q8N531 8 144355431-144359376 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 43.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008867 Approved Nucleoplasm,Vesicles Yes No "Cluster 14: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" Nucleoplasm Vesicles "HPA008867: AB_2668161" "unprognostic (2.97e-2)" "unprognostic (3.30e-2)" "unprognostic (1.13e-3)" "unprognostic (3.13e-1)" "unprognostic (9.88e-2)" "unprognostic (1.68e-1)" "unprognostic (6.29e-3)" "unprognostic (2.62e-1)" "unprognostic (1.10e-1)" "unprognostic (1.43e-2)" "unprognostic (9.04e-2)" "unprognostic (9.73e-2)" "prognostic unfavorable (4.49e-10)" "unprognostic (3.93e-2)" "unprognostic (1.44e-1)" "unprognostic (3.53e-1)" "unprognostic (2.00e-1)" 4.6 4.8 2.3 1.4 2.3 2.0 4.9 2.5 3.2 4.3 2.5 8.0 4.6 3.5 0.6 7.2 3.1 1.0 4.1 2.3 2.2 4.6 10.8 3.9 1.8 2.5 2.4 2.1 8.1 1.6 3.8 1.8 2.4 4.2 1.8 0.5 5.1 1.6 4.2 6.6 7.8 0.7 2.4 6.8 5.5 5.2 2.6 1.5 3.3 0.3 1.2 4.6 4.3 2.3 9.0 3.0 2.1 13.3 2.7 0.7 3.8 4.4 5.1 4.5 3.1 3.2 3.9 4.1 5.3 2.2 2.2 5.8 2.4 6.1 1.0 7.6 3.0 8.2 1.6 7.9 4.0 2.1 8.4 1.2 5.5 2.5 6.6 1.2 3.7 6.7 3.8 6.6 1.7 16.7 6.0 1.9 2.6 9.8 8.3 6.7 2.4 14.0 6.0 3.0 3.1 3.0 5.1 8.0 7.7 1.2 13.2 3.7 3.3 2.2 8.1 10.8 5.4 2.5 2.1 3.0 3.4 5.1 2.9 0.0 0.1 0.6 0.4 0.4 0.3 0.2 0.2 0.2 0.1 0.1 0.0 0.1 0.0 0.3 1.6 0.7 0.0 0.0 2.3 2.3 2.5 3.2 2.3 2.2 2.5 2.4 2.4 2.4 2.6 2.3 17.9 6.4 2.0 4.6 10.1 5.7 6.0 2.1 7.4 9.9 13.2 12.8 1.1 7.2 4.6 0.0 14.6 8.3 17.3 18.2 5.9 5.2 1.9 5.2 6.8 5.9 2.4 3.0 7.4 6.2 11.6 5.2 13.7 7.8 1.3 7.7 6.8 6.7 6.9 1.7 5.6 19.4 2.0 4.7 7.6 1.6 5.3 9.0 5.4 4.7 2.6 7.9 6.2 2.0 2.7 7.5 10.8 1.9 20.1 8.2 43.7 8.1 2.0 9.0 0.0 5.1 13.6 5.0 7.8 14.8 6.7 3.8 10.7 9.9 17.3 6.3 FBXO16 FBX16 ENSG00000214050 "F-box protein 16" Q8IX29 8 28348287-28490278 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 18.4;pituitary gland: 17.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 35.5;Excitatory neurons: 44.4;Inhibitory neurons: 43.6;Rod photoreceptor cells: 48.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 9.6" "Lineage enriched" "Detected in single" 10 "dendritic cells: 9.6" "Cell line enhanced" "Detected in many" "AF22: 20.3;Karpas-707: 22.4" "Low region specificity" "Detected in all" "HPA058676, HPA076472" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles, Plasma membrane, Cytosol" "HPA058676: AB_2683795, HPA076472: " "unprognostic (3.44e-1)" "unprognostic (1.44e-1)" "unprognostic (3.37e-3)" "unprognostic (5.56e-3)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (2.55e-3)" "unprognostic (4.95e-3)" "unprognostic (6.49e-2)" "prognostic favorable (6.70e-5)" "unprognostic (3.41e-3)" "unprognostic (4.90e-2)" "unprognostic (7.15e-2)" "unprognostic (1.71e-2)" "unprognostic (4.85e-2)" "unprognostic (2.72e-2)" "unprognostic (2.07e-1)" 0.5 1.8 3.9 0.9 5.0 2.2 2.6 6.8 7.0 4.1 2.9 1.6 2.0 1.1 18.4 0.7 4.4 1.4 1.4 4.6 3.9 3.2 6.0 1.5 1.4 1.1 1.7 0.7 4.7 7.1 17.3 0.6 2.0 3.5 2.0 14.3 3.4 5.1 1.1 0.4 2.9 0.7 0.3 1.2 2.2 4.2 3.5 0.6 7.0 0.9 2.8 1.2 0.7 4.3 16.5 2.9 20.3 7.5 0.5 0.0 0.3 0.2 0.5 3.0 5.5 3.1 4.6 5.8 7.2 0.1 8.1 5.1 2.3 3.5 3.0 2.6 3.6 2.7 0.3 1.7 0.0 3.5 1.9 0.2 10.8 0.7 3.2 1.5 0.0 5.6 1.1 22.4 1.0 5.7 0.5 5.0 3.9 2.2 4.5 0.2 4.5 8.2 3.9 2.4 13.1 5.4 0.4 3.3 9.5 3.5 13.8 5.9 0.6 1.6 5.8 3.2 3.0 5.2 5.0 5.2 6.8 0.7 3.5 0.3 0.1 0.1 0.1 0.1 0.3 0.3 0.2 0.1 0.7 0.2 0.1 0.2 0.9 0.0 0.1 9.6 0.2 0.1 3.9 5.0 6.8 7.0 4.6 3.9 1.1 1.7 2.0 0.3 3.5 4.3 0.0 3.2 4.1 7.5 1.7 0.1 3.0 10.9 5.2 8.2 3.9 3.4 2.1 8.6 7.9 3.7 35.5 0.6 0.0 0.5 7.9 5.3 12.1 13.5 1.3 0.2 10.2 0.0 44.4 4.6 0.4 0.9 1.5 6.4 0.0 1.9 0.4 1.9 2.7 5.0 43.6 3.9 4.1 0.8 2.3 12.4 1.2 0.4 0.0 2.8 0.0 9.3 0.0 23.6 3.2 3.1 0.4 0.7 11.1 1.7 0.2 4.7 23.4 48.6 0.0 0.5 1.8 10.5 5.6 1.2 0.0 0.0 0.5 4.2 1.0 1.7 FBXO46 "20D7-FC4, Fbx46, FBXO34L" ENSG00000177051 "F-box protein 46" Q6PJ61 19 45710629-45730896 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 35.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HeLa: 84.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049390 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Vesicles" Cytosol "HPA049390: AB_2680742" "unprognostic (9.02e-3)" "unprognostic (1.01e-2)" "unprognostic (2.82e-2)" "prognostic unfavorable (2.13e-5)" "unprognostic (9.33e-2)" "prognostic favorable (5.44e-4)" "prognostic unfavorable (1.11e-4)" "unprognostic (1.08e-1)" "unprognostic (2.06e-1)" "unprognostic (6.13e-2)" "prognostic favorable (8.11e-4)" "unprognostic (9.77e-2)" "prognostic unfavorable (5.33e-4)" "unprognostic (5.10e-2)" "unprognostic (1.46e-1)" "unprognostic (3.27e-2)" "prognostic favorable (5.09e-6)" 7.5 7.2 10.6 11.1 11.0 9.2 8.9 9.5 12.6 13.5 18.4 11.7 7.6 13.6 7.5 21.4 10.3 5.1 8.5 8.8 12.2 7.9 10.5 7.4 14.7 8.7 9.6 14.1 9.6 5.8 9.4 6.6 11.5 9.8 7.5 9.9 10.1 5.3 11.4 13.4 11.1 6.3 6.0 14.4 10.8 12.3 9.9 11.1 10.4 5.4 13.9 9.3 13.0 20.9 14.0 21.5 16.2 18.9 4.1 7.3 18.3 7.1 4.0 5.6 6.5 17.8 17.9 24.1 9.5 4.0 7.9 19.9 12.1 9.1 4.2 30.0 25.5 19.6 84.1 9.8 6.2 8.7 24.2 6.1 8.1 9.5 5.9 14.0 8.4 29.4 15.6 28.4 4.6 13.2 20.3 10.2 10.2 13.0 7.3 27.3 9.0 22.6 6.7 16.3 16.1 14.1 11.4 23.7 9.4 15.3 20.1 10.7 9.6 11.8 10.6 6.5 12.0 27.2 41.0 16.1 13.1 12.3 9.8 4.6 1.1 1.2 1.8 0.9 1.2 2.1 1.3 1.3 0.8 3.8 1.2 1.4 3.3 0.6 1.2 1.3 1.4 0.7 10.6 11.0 9.5 12.6 8.8 12.2 8.7 9.6 11.5 6.0 9.9 20.9 4.8 9.6 4.8 6.2 6.5 26.0 10.0 5.7 9.1 3.3 12.7 8.5 5.4 10.0 6.1 7.3 2.1 7.9 3.4 16.3 1.9 6.5 2.9 8.0 5.1 5.2 7.3 5.9 6.5 4.9 19.0 3.6 6.1 9.2 3.8 11.4 4.2 21.1 3.7 11.8 5.5 12.7 0.0 5.7 8.8 3.1 5.6 3.3 5.4 5.6 5.6 4.0 7.2 4.0 6.1 6.9 12.2 1.9 5.5 8.0 6.3 2.2 7.2 3.4 0.0 3.6 4.7 6.5 4.6 13.3 35.8 12.4 5.1 4.9 9.3 11.1 FBXW11 "BTRC2, BTRCP2, Fbw11, Fbw1b, FBXW1B, Hos, KIAA0696" ENSG00000072803 "F-box and WD repeat domain containing 11" Q9UKB1 5 171861549-172006873 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Ubl conjugation pathway, Wnt signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072204 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Vesicles, Plasma membrane" Nucleoplasm "HPA072204: AB_2686493" "unprognostic (4.04e-3)" "unprognostic (1.27e-1)" "unprognostic (2.69e-2)" "unprognostic (5.79e-2)" "unprognostic (1.39e-1)" "unprognostic (1.06e-1)" "unprognostic (1.90e-2)" "unprognostic (1.63e-1)" "unprognostic (6.87e-2)" "unprognostic (9.43e-2)" "unprognostic (1.53e-1)" "unprognostic (8.14e-3)" "unprognostic (2.38e-3)" "unprognostic (1.57e-1)" "unprognostic (1.54e-1)" "unprognostic (3.76e-3)" "unprognostic (1.76e-1)" 19.5 20.4 33.3 13.6 38.2 8.2 17.0 34.7 41.6 19.9 27.4 14.6 12.6 22.9 12.4 24.2 27.0 17.5 36.1 38.0 35.5 23.0 20.7 17.6 16.7 33.3 34.4 25.6 29.1 33.1 14.2 13.9 33.1 19.0 16.0 37.2 13.5 20.3 34.5 13.7 13.2 26.1 34.4 18.1 20.0 14.3 37.7 17.3 21.1 35.6 22.0 19.2 15.8 42.4 35.4 35.6 52.0 45.2 39.9 40.2 26.4 37.1 51.7 45.0 54.9 36.7 23.1 32.5 44.3 46.4 72.0 22.8 37.6 56.3 74.6 42.7 37.3 26.2 35.0 28.5 35.4 29.8 36.0 28.5 38.2 36.8 59.8 48.5 38.6 27.3 16.6 31.7 55.7 26.5 20.7 15.3 19.8 20.8 39.5 30.1 43.7 22.0 34.8 29.2 21.6 37.2 32.9 27.3 70.8 38.7 34.2 31.0 33.8 44.3 22.0 27.4 37.2 31.8 38.9 22.2 31.3 27.8 34.6 25.4 7.3 7.2 5.8 5.1 6.1 8.5 4.8 5.7 7.3 8.4 4.3 5.7 7.1 14.1 5.7 8.6 5.7 6.6 33.3 38.2 34.7 41.6 38.0 35.5 33.3 34.4 33.1 34.4 37.7 42.4 35.4 25.6 21.2 75.4 52.7 19.1 15.6 21.8 32.5 43.5 26.4 22.1 59.1 42.9 20.8 27.6 8.4 8.5 49.8 25.1 43.0 33.7 32.9 42.0 47.9 26.3 28.8 27.4 86.5 36.9 7.8 24.7 38.2 51.0 20.8 25.8 29.3 43.1 12.8 35.3 85.3 21.6 20.3 29.6 25.3 34.3 29.5 26.6 12.4 62.8 24.6 63.6 16.5 75.9 94.4 54.1 14.9 28.6 36.5 30.2 21.5 52.4 17.1 34.3 46.0 28.2 33.5 34.5 16.0 28.7 23.7 12.0 28.8 17.2 15.0 32.9 FBXW12 "Fbw12, FBXO35" ENSG00000164049 "F-box and WD repeat domain containing 12" Q6X9E4 3 48372219-48401259 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "pancreas: 6.1" "Group enriched" "Detected in some" 4 "Early spermatids: 12.4;Late spermatids: 7.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA037491, HPA037492" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 25: Pancreas - Digestion" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol Vesicles "HPA037491: AB_2675504, HPA037492: AB_2675505" "unprognostic (5.38e-2)" "unprognostic (1.90e-1)" "unprognostic (2.81e-1)" "unprognostic (1.69e-1)" "unprognostic (1.25e-1)" "unprognostic (1.63e-2)" "unprognostic (8.56e-2)" "unprognostic (2.17e-1)" "unprognostic (9.48e-2)" "unprognostic (2.95e-1)" "unprognostic (1.21e-3)" "unprognostic (6.96e-3)" "unprognostic (2.36e-1)" "unprognostic (6.29e-3)" "unprognostic (1.43e-1)" "unprognostic (1.29e-1)" "unprognostic (8.81e-3)" 0.0 0.0 0.3 0.0 0.3 0.0 0.1 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.1 0.2 0.1 6.1 0.0 0.1 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.4 0.5 0.6 0.4 0.1 0.2 0.2 0.1 0.2 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.4 0.6 0.2 0.0 0.0 0.0 2.3 0.0 0.0 0.1 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.0 1.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 FBXW7 "AGO, CDC4, FBW7, FBX30, FBXW6, FLJ11071, SEL-10, SEL10" ENSG00000109670 "F-box and WD repeat domain containing 7" Q969H0 4 152320544-152536092 "Cancer-related genes, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 66.9" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 201.8;Excitatory neurons: 529.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 23.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 79.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013793, CAB029987" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "CAB013793: AB_2533451, CAB029987: AB_2246842" "unprognostic (3.32e-1)" "unprognostic (9.02e-2)" "unprognostic (1.84e-2)" "unprognostic (3.08e-2)" "unprognostic (3.87e-1)" "unprognostic (1.36e-3)" "unprognostic (4.37e-1)" "unprognostic (1.94e-1)" "unprognostic (8.28e-2)" "unprognostic (3.29e-1)" "unprognostic (5.32e-3)" "unprognostic (3.19e-2)" "prognostic unfavorable (1.52e-4)" "unprognostic (3.38e-2)" "unprognostic (1.41e-1)" "unprognostic (5.49e-3)" "unprognostic (2.17e-3)" 14.2 9.5 37.9 15.0 43.1 19.8 14.2 54.3 66.9 8.7 6.7 9.5 7.8 8.6 24.3 14.3 15.6 9.2 24.7 48.2 23.0 6.7 11.2 11.4 16.1 17.1 20.9 9.1 12.8 7.8 9.2 9.4 18.1 7.8 10.3 18.0 11.8 7.5 26.0 63.1 10.4 9.1 11.8 16.2 13.0 22.8 29.4 14.7 10.3 19.7 20.3 11.9 10.7 47.4 9.8 8.0 19.1 14.2 12.2 9.4 16.2 13.4 12.9 8.5 8.1 15.7 12.0 24.7 3.9 13.7 6.5 5.2 16.9 30.9 12.1 16.2 8.0 11.9 10.7 10.9 12.7 29.2 10.6 14.8 45.7 15.2 24.4 8.4 15.2 20.5 19.2 25.7 10.8 13.7 34.9 10.6 9.7 8.0 6.1 32.2 8.0 5.3 9.8 17.0 12.7 10.2 8.5 11.3 7.5 21.6 6.4 12.6 15.6 11.3 12.6 5.4 8.2 79.0 47.5 24.4 9.4 9.2 8.3 23.5 2.7 1.6 4.0 3.0 2.7 2.8 3.1 2.7 1.6 1.8 3.4 2.5 4.8 7.1 2.2 2.1 2.9 1.3 37.9 43.1 54.3 66.9 48.2 23.0 17.1 20.9 18.1 11.8 29.4 47.4 29.5 9.6 22.9 80.0 48.1 201.8 36.5 29.9 120.1 74.9 32.1 30.9 61.8 12.8 15.1 9.2 31.3 10.9 54.7 22.2 3.9 14.3 17.4 37.7 37.3 36.1 14.5 30.1 529.6 13.5 39.9 27.2 21.4 61.6 15.8 19.1 17.9 18.3 10.5 11.8 186.5 16.4 32.6 18.8 47.0 10.2 15.2 33.7 28.4 172.4 28.0 37.0 35.0 102.5 99.8 18.7 18.2 11.3 174.5 36.3 8.9 7.5 11.9 41.4 13.1 33.2 25.5 74.1 87.2 57.0 174.9 31.2 46.2 18.7 14.9 70.5 FCGR1A "CD64, CD64A" ENSG00000150337 "Fc fragment of IgG receptor Ia" P12314 1 149782671-149791675 "CD markers, FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 93.3;lymphoid tissue: 41.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 283.3;Kupffer cells: 140.9;Late spermatids: 64.9;Macrophages: 94.9" "Cancer enriched" "Detected in many" 4 "glioma: 10.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 131.5;intermediate monocyte: 54.7;myeloid DC: 35.6;neutrophil: 93.4" "Group enriched" "Detected in many" 53 "dendritic cells: 35.6;granulocytes: 93.4;monocytes: 131.5" "Cell line enriched" "Detected in some" 5 "THP-1: 191.6" "Low region specificity" "Detected in all" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (5.27e-2)" "unprognostic (2.89e-2)" "unprognostic (2.34e-2)" "unprognostic (7.97e-2)" "unprognostic (8.44e-3)" "unprognostic (1.73e-1)" "unprognostic (7.69e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-2)" "unprognostic (1.72e-1)" "unprognostic (1.98e-2)" "unprognostic (6.18e-2)" "prognostic unfavorable (4.83e-8)" "unprognostic (1.28e-1)" "unprognostic (4.51e-2)" "unprognostic (9.99e-2)" "unprognostic (9.03e-2)" 12.2 7.2 8.4 41.3 8.9 17.9 3.6 8.8 12.8 4.2 8.4 2.3 1.1 1.6 93.3 1.7 1.8 8.2 2.2 8.6 9.4 2.8 4.2 28.6 14.4 14.6 10.6 2.3 4.3 2.7 2.5 32.6 13.0 1.6 2.1 2.3 1.9 2.4 0.3 0.4 1.3 19.1 13.2 12.5 2.1 3.7 12.2 1.4 1.4 0.8 0.8 14.7 0.8 18.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 13.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.3 191.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 24.4 0.0 2.0 131.5 1.6 0.0 54.7 0.7 1.6 0.0 0.3 35.6 0.0 0.0 0.1 93.4 0.0 11.8 0.9 0.3 48.5 8.4 8.9 8.8 12.8 8.6 9.4 14.6 10.6 13.0 13.2 12.2 18.9 0.3 0.0 3.1 0.0 0.8 0.1 0.0 0.0 0.6 1.5 0.2 0.8 1.7 1.5 1.3 0.0 2.1 2.7 0.0 0.0 0.0 0.0 30.8 0.1 0.1 9.3 0.0 2.7 0.1 0.0 1.3 1.0 0.0 0.1 0.0 0.2 1.8 0.5 283.3 0.0 0.1 0.0 0.0 140.9 6.0 64.9 0.3 94.9 0.0 7.5 34.7 0.3 0.0 0.5 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.7 1.3 6.6 0.2 0.3 0.6 0.4 0.1 0.0 4.1 0.6 0.1 0.1 0.0 FCGR1B CD64b ENSG00000198019 "Fc fragment of IgG receptor Ib" Q92637 1 121087345-121097161 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 51.5;lymphoid tissue: 18.9" "Cell type enhanced" "Detected in some" "Hofbauer cells: 86.5;Kupffer cells: 51.5;Late spermatids: 14.6;Macrophages: 36.6;monocytes: 16.4;Sertoli cells: 19.7" "Cancer enriched" "Detected in single" 4 "glioma: 1.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 31.2;neutrophil: 36.3" "Group enriched" "Detected in many" 4 "granulocytes: 36.3;monocytes: 31.2" "Group enriched" "Detected in some" 6 "NB-4: 19.8;THP-1: 73.9" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (3.21e-2)" "unprognostic (4.35e-2)" "unprognostic (1.13e-2)" "unprognostic (2.84e-1)" "unprognostic (1.85e-1)" "unprognostic (9.60e-2)" "unprognostic (1.56e-2)" "unprognostic (6.42e-2)" "unprognostic (3.10e-2)" "unprognostic (8.17e-2)" "unprognostic (1.91e-1)" "unprognostic (3.65e-1)" "unprognostic (3.24e-10)" "unprognostic (8.99e-2)" "unprognostic (2.85e-2)" "unprognostic (7.86e-3)" "unprognostic (8.93e-2)" 5.0 3.0 4.4 18.9 4.5 6.6 1.8 4.5 7.8 1.0 3.7 0.7 0.5 0.7 51.5 0.7 0.8 1.9 1.1 4.6 4.7 1.4 1.7 6.8 2.2 6.1 5.7 0.6 2.6 0.7 1.0 11.0 6.2 0.8 0.8 0.8 0.9 0.6 0.4 0.2 0.7 5.8 6.0 7.2 0.9 0.7 6.2 0.4 2.1 0.1 0.3 4.0 0.4 6.4 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 5.9 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 19.8 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.1 0.0 0.3 1.0 73.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 31.2 0.6 0.0 19.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 36.3 0.0 12.4 0.3 0.0 8.8 4.4 4.5 4.5 7.8 4.6 4.7 6.1 5.7 6.2 6.0 6.2 6.4 0.4 0.0 2.0 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.1 0.6 2.2 0.0 0.6 0.0 2.1 0.8 0.1 0.1 0.0 0.0 7.7 0.2 0.2 2.0 0.0 0.8 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.4 0.4 0.3 86.5 3.3 0.1 0.0 0.0 51.5 4.1 14.6 1.2 36.6 0.0 11.2 16.4 0.1 1.0 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.4 19.7 0.6 0.1 0.5 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.1 FCHO2 ENSG00000157107 "FCH and mu domain containing endocytic adaptor 2" Q0JRZ9 5 72956041-73090522 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 19.3;neutrophil: 20.6" "Group enriched" "Detected in many" 9 "granulocytes: 20.6;monocytes: 6.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037685, HPA037686, HPA077850" Enhanced Approved Vesicles,Centrosome,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 28: BEWO - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Centrosome "Vesicles, Cytosol" "HPA037685: AB_2675610, HPA037686: AB_10673636, HPA077850: AB_2686860" "unprognostic (1.14e-1)" "unprognostic (2.78e-1)" "unprognostic (1.01e-2)" "unprognostic (1.10e-1)" "unprognostic (6.59e-2)" "unprognostic (2.68e-3)" "unprognostic (4.99e-2)" "unprognostic (6.25e-2)" "unprognostic (1.31e-1)" "unprognostic (5.67e-2)" "unprognostic (6.56e-3)" "unprognostic (1.21e-1)" "prognostic favorable (7.00e-5)" "unprognostic (1.43e-1)" "unprognostic (3.27e-3)" "unprognostic (9.59e-2)" "unprognostic (1.76e-1)" 16.6 9.8 5.1 11.3 6.5 10.7 15.0 9.8 9.1 14.5 11.4 16.3 17.1 16.1 9.0 29.6 11.3 16.9 10.6 5.2 5.0 19.7 17.9 21.8 11.0 6.7 5.6 14.9 9.1 15.3 4.1 21.2 6.4 13.0 17.1 9.1 11.6 12.6 10.4 12.3 18.6 13.4 5.3 17.1 13.6 7.2 8.8 5.2 24.0 12.2 9.2 14.9 16.5 9.5 15.0 11.8 11.3 9.9 15.6 20.5 33.0 12.9 19.0 9.6 15.1 6.0 25.6 3.5 17.6 18.0 17.8 11.1 9.6 22.6 13.0 3.8 11.3 7.3 9.9 7.6 7.8 1.5 7.3 13.8 11.5 12.8 20.6 21.9 22.3 3.5 8.4 6.2 20.2 7.0 0.0 7.3 3.6 3.0 6.1 3.2 10.8 4.4 23.4 20.8 4.5 7.1 17.7 12.6 8.3 15.7 15.1 10.4 23.1 12.5 5.8 13.9 9.3 2.2 4.4 0.7 8.1 1.1 15.8 19.3 3.2 8.8 1.5 4.6 1.0 0.4 0.5 0.6 1.4 0.9 0.2 0.5 20.6 0.9 6.6 0.5 0.4 0.8 5.1 6.5 9.8 9.1 5.2 5.0 6.7 5.6 6.4 5.3 8.8 9.5 51.8 57.7 44.3 34.9 3.8 10.5 15.6 12.0 12.5 11.1 16.5 12.3 15.1 14.3 23.1 35.0 4.2 14.2 7.0 25.6 13.7 16.0 2.4 24.3 17.0 36.8 14.9 12.6 78.2 17.5 8.9 22.8 17.3 38.3 18.3 9.5 52.1 11.0 19.8 11.8 51.5 14.8 8.2 81.0 13.0 2.8 13.4 45.8 16.0 71.2 12.9 15.4 3.1 62.4 59.1 30.7 29.4 13.9 3.5 22.5 21.0 21.8 21.5 8.9 26.3 25.1 21.3 16.9 14.3 15.0 15.3 13.7 4.4 9.1 14.0 30.2 FCSK "FLJ39408, FUK" ENSG00000157353 "Fucose kinase" Q8N0W3 16 70454595-70480274 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 2.7;Cardiomyocytes: 4.2;Cytotrophoblasts: 5.5;Extravillous trophoblasts: 3.0;Hofbauer cells: 5.0;Syncytiotrophoblasts: 5.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041971 Approved Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 24: Non-specific - Transcription regulation" Vesicles "HPA041971: AB_10795648" "unprognostic (4.55e-1)" "unprognostic (3.21e-1)" "unprognostic (1.73e-2)" "unprognostic (3.95e-2)" "unprognostic (3.79e-2)" "unprognostic (2.64e-2)" "unprognostic (8.79e-3)" "unprognostic (1.26e-1)" "unprognostic (1.49e-1)" "unprognostic (1.57e-1)" "unprognostic (4.82e-3)" "unprognostic (4.85e-2)" "prognostic favorable (8.91e-4)" "unprognostic (2.49e-2)" "unprognostic (9.68e-2)" "unprognostic (8.89e-2)" "prognostic favorable (8.38e-4)" 3.9 7.2 5.4 5.4 7.1 5.0 4.9 8.2 7.7 5.6 7.5 7.5 10.1 4.9 2.4 5.6 5.5 3.8 4.3 5.3 5.0 8.9 8.2 4.8 5.4 6.4 4.6 6.6 8.3 9.1 9.8 3.6 5.7 6.3 3.9 2.9 5.9 4.4 5.5 7.2 7.4 3.1 4.5 6.4 6.6 4.5 5.7 3.8 7.9 2.3 2.8 4.8 4.8 11.1 3.4 4.6 2.5 5.8 1.5 1.8 10.0 1.8 2.8 2.2 3.0 4.2 10.0 2.3 8.8 1.7 0.7 4.8 1.8 4.7 1.6 4.4 6.5 2.9 8.9 4.5 3.7 3.8 2.3 3.0 5.4 2.1 4.4 3.3 4.3 4.6 5.9 2.6 1.8 10.3 4.6 9.2 1.6 5.5 2.7 7.0 0.6 10.4 5.9 5.5 4.0 5.3 10.1 3.7 5.3 1.9 14.8 7.5 5.0 1.8 2.4 4.0 2.2 9.5 5.1 4.8 3.3 3.8 4.2 0.2 1.9 0.8 1.9 1.0 1.6 0.8 1.9 1.9 1.1 1.5 2.6 1.2 1.6 1.2 1.2 1.3 1.4 1.2 5.4 7.1 8.2 7.7 5.3 5.0 6.4 4.6 5.7 4.5 5.7 11.1 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 5.5 1.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 3.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 5.2 0.2 0.0 0.0 0.0 FERMT3 "KIND3, MGC10966, MIG-2, MIG2B, UNC112C, URP2" ENSG00000149781 "Fermitin family member 3" Q86UX7 11 64206678-64223891 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 180.6;lymphoid tissue: 130.1" "Cell type enhanced" "Detected in many" "dendritic cells: 118.3;granulocytes: 96.4;Hofbauer cells: 193.1;Kupffer cells: 95.8;Langerhans cells: 88.0;Macrophages: 232.9;monocytes: 142.9;NK-cells: 93.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 306.9;HL-60: 135.9;HMC-1: 314.2;Karpas-707: 127.6;MOLT-4: 121.8;NB-4: 174.1;U-937: 138.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA065231 Approved Vesicles NA NA 160000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA065231: AB_2685439" "unprognostic (1.96e-2)" "unprognostic (1.07e-2)" "unprognostic (3.38e-3)" "prognostic favorable (9.89e-4)" "unprognostic (8.77e-2)" "unprognostic (1.83e-2)" "unprognostic (3.56e-2)" "unprognostic (2.46e-1)" "unprognostic (4.20e-1)" "unprognostic (3.98e-1)" "unprognostic (2.70e-1)" "unprognostic (3.88e-1)" "prognostic unfavorable (2.12e-5)" "unprognostic (3.08e-3)" "unprognostic (5.25e-2)" "unprognostic (4.97e-2)" "unprognostic (1.75e-1)" 25.1 14.5 9.4 63.3 11.6 180.6 13.0 11.2 18.1 8.5 12.2 17.3 22.0 8.4 0.7 6.4 13.6 15.6 12.0 9.8 11.6 11.1 12.5 46.2 89.2 17.9 12.2 5.1 7.0 1.3 5.9 15.0 13.2 8.2 8.1 0.6 10.7 4.4 6.0 7.1 34.1 9.4 13.3 130.1 29.6 4.5 17.1 48.7 10.0 4.6 41.8 19.8 7.3 15.3 1.2 1.6 0.5 0.9 0.3 0.8 2.0 1.4 0.2 0.4 0.3 2.6 2.3 32.6 3.2 6.3 0.7 2.4 1.0 0.5 0.5 83.9 0.6 306.9 1.6 0.1 10.8 135.9 314.2 1.2 1.1 5.2 0.0 0.5 81.2 77.0 7.3 127.6 8.6 3.5 121.8 174.1 1.2 1.0 2.3 72.4 8.8 0.7 0.3 0.7 1.9 0.5 0.7 4.5 1.7 0.7 2.0 92.6 7.8 1.1 2.5 1.9 0.9 1.5 3.3 59.4 19.5 138.9 86.6 204.1 207.0 236.5 120.0 192.6 114.9 54.5 94.1 112.0 162.0 53.1 60.9 80.6 184.6 102.4 151.2 195.7 120.9 292.6 9.4 11.6 11.2 18.1 9.8 11.6 17.9 12.2 13.2 13.3 17.1 15.3 3.8 9.6 14.7 0.7 52.1 4.7 0.9 0.3 3.4 0.5 3.3 5.2 2.4 4.3 3.9 0.0 0.0 1.2 118.3 6.1 0.0 0.8 0.4 4.3 5.6 7.9 0.0 62.5 1.2 2.4 1.4 5.4 19.9 7.3 96.4 0.4 19.6 1.4 193.1 0.0 1.5 32.1 0.0 95.8 88.0 0.9 0.9 232.9 17.8 5.6 142.9 0.3 93.7 1.0 1.5 4.3 10.9 2.6 35.2 0.9 8.2 0.4 1.0 0.3 6.6 13.7 6.6 1.2 0.8 1.9 4.5 2.6 78.5 1.4 15.0 0.7 FES FPS ENSG00000182511 "FES proto-oncogene, tyrosine kinase" P07332 15 90883695-90895776 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 83.4;lymphoid tissue: 110.9" "Cell type enhanced" "Detected in many" "Adipocytes: 46.8;Hofbauer cells: 48.7;Kupffer cells: 92.3;Macrophages: 51.9;monocytes: 57.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 315.8" "Group enriched" "Detected in many" 4 "dendritic cells: 162.6;granulocytes: 315.8;monocytes: 151.7" "Cell line enhanced" "Detected in many" "HEL: 63.5;HL-60: 56.9;HMC-1: 116.6;NB-4: 76.1;THP-1: 110.8;U-937: 48.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001376 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" Vesicles "HPA001376: AB_1078847" "unprognostic (1.07e-2)" "unprognostic (2.54e-2)" "prognostic unfavorable (5.78e-4)" "unprognostic (2.31e-2)" "unprognostic (4.05e-3)" "unprognostic (7.33e-2)" "unprognostic (1.74e-1)" "unprognostic (2.22e-1)" "unprognostic (1.58e-3)" "unprognostic (1.35e-1)" "unprognostic (4.66e-2)" "unprognostic (5.15e-3)" "unprognostic (1.78e-3)" "unprognostic (2.53e-3)" "unprognostic (6.08e-2)" "unprognostic (1.18e-1)" "unprognostic (1.40e-1)" 30.8 8.0 9.4 20.2 8.8 83.4 21.3 9.6 10.8 18.1 9.6 12.5 5.8 15.7 2.4 5.9 19.0 14.0 19.6 8.3 8.7 18.9 25.2 30.9 13.8 11.1 9.2 13.5 7.8 2.3 5.6 16.3 10.1 17.9 4.6 1.5 58.3 8.0 6.1 8.0 12.5 10.7 10.4 110.9 9.6 4.5 10.9 4.2 16.0 7.0 5.7 15.1 13.5 9.8 0.4 0.8 0.8 10.3 3.1 8.8 17.9 2.9 0.1 5.1 2.9 2.6 0.1 6.8 0.5 6.0 0.2 1.5 1.7 0.3 1.6 3.3 1.1 63.5 0.0 11.9 6.8 56.9 116.6 8.8 0.1 7.6 0.0 0.0 31.2 9.4 1.8 0.2 0.0 21.3 1.8 76.1 3.2 2.5 0.0 8.6 0.1 0.1 0.0 0.2 0.4 0.1 0.0 2.8 2.3 2.9 0.1 110.8 24.9 0.2 10.4 0.2 0.2 0.1 8.0 2.5 0.3 48.0 2.4 64.4 151.7 315.8 0.5 88.6 0.4 5.2 0.3 0.4 162.6 4.1 0.2 0.3 100.5 51.4 39.8 65.0 0.2 81.5 9.4 8.8 9.6 10.8 8.3 8.7 11.1 9.2 10.1 10.4 10.9 9.8 46.8 3.2 5.8 3.6 5.0 3.8 5.4 0.5 0.6 0.2 4.1 3.8 3.4 8.6 0.5 1.8 0.0 5.3 25.6 0.6 3.9 7.3 1.7 2.0 4.2 29.1 3.0 8.0 2.8 4.3 4.2 9.0 2.0 4.2 29.2 10.7 20.0 15.0 48.7 0.0 0.2 2.0 2.0 92.3 27.9 8.4 9.0 51.9 7.2 5.6 57.8 2.5 26.8 2.0 0.3 2.1 2.0 10.1 4.0 3.1 0.7 1.5 0.2 1.9 13.1 4.6 12.9 4.4 15.9 1.0 2.8 4.5 6.7 3.3 3.7 5.2 FETUB ENSG00000090512 "Fetuin B" Q9UGM5 3 186635969-186653141 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "liver: 234.6" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 47.2" "Cancer enriched" "Detected in some" 12 "liver cancer: 44.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035132, HPA035133" Supported Approved Vesicles "Secreted to blood" NA NA 47500000000 3600000000 "Cluster 62: Liver - Hemostasis" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA035132: AB_10601650, HPA035133: " "unprognostic (9.01e-2)" "unprognostic (1.95e-1)" "unprognostic (4.62e-1)" "unprognostic (8.74e-2)" "unprognostic (6.28e-3)" "unprognostic (1.24e-2)" "unprognostic (7.55e-2)" "unprognostic (9.78e-2)" "unprognostic (1.73e-2)" "unprognostic (9.18e-2)" "unprognostic (1.79e-1)" "unprognostic (8.39e-2)" 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 1.6 0.0 0.1 0.0 0.0 0.0 8.7 0.0 0.0 0.0 0.1 0.0 0.4 234.6 0.0 0.0 0.1 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.8 0.0 0.1 2.7 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 5.8 0.0 2.4 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 3.9 0.0 5.3 0.2 0.2 0.1 0.0 2.7 0.2 0.2 0.0 0.0 0.0 1.4 0.0 0.0 0.7 47.2 0.0 0.0 0.0 0.2 0.0 2.9 0.0 5.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 FGD6 "FLJ11183, ZFYVE24" ENSG00000180263 "FYVE, RhoGEF and PH domain containing 6" Q6ZV73 12 95076749-95217482 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 109.0;Microglial cells: 90.9;Pancreatic endocrine cells: 78.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 23.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007974 Approved Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 31: Skin - Epidermis development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA007974: AB_1848520" "unprognostic (1.28e-2)" "unprognostic (2.67e-3)" "unprognostic (6.06e-2)" "unprognostic (5.56e-2)" "unprognostic (1.65e-1)" "unprognostic (4.70e-2)" "unprognostic (4.66e-2)" "unprognostic (1.35e-3)" "unprognostic (1.32e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (4.62e-5)" "prognostic unfavorable (9.83e-4)" "prognostic unfavorable (5.46e-6)" "unprognostic (1.01e-2)" "unprognostic (1.38e-1)" "unprognostic (3.33e-2)" "unprognostic (1.92e-1)" 1.8 3.3 3.3 5.1 5.3 1.5 2.9 0.3 5.2 3.3 4.0 4.5 1.3 3.4 1.2 3.3 1.9 4.9 3.6 3.2 0.4 3.3 3.1 5.2 5.5 2.0 1.7 4.5 3.4 1.2 1.1 4.3 0.3 3.3 4.2 2.2 2.2 4.0 1.6 7.8 3.5 3.5 1.8 3.3 1.8 3.0 2.9 2.5 5.2 1.3 9.7 3.3 3.5 1.6 22.5 20.1 18.2 2.0 1.9 1.8 9.5 3.1 4.4 1.1 1.8 7.7 15.0 23.8 5.1 2.0 1.3 8.9 3.3 18.7 2.6 2.5 2.0 1.1 3.2 3.8 2.5 2.5 0.2 7.5 8.4 2.2 22.1 7.3 11.9 3.2 5.1 0.4 0.6 1.2 2.0 0.5 7.5 2.8 6.9 5.5 3.6 1.9 12.8 7.1 3.0 4.9 9.0 4.6 0.4 9.1 2.1 0.2 16.4 0.7 2.0 0.9 2.4 2.2 5.3 6.7 0.9 1.6 1.4 0.2 1.6 0.0 0.0 2.5 0.0 0.5 0.0 0.0 0.9 1.4 0.1 0.0 0.1 0.1 2.0 0.0 0.0 0.6 3.3 5.3 0.3 5.2 3.2 0.4 2.0 1.7 0.3 1.8 2.9 1.6 12.4 16.0 17.0 109.0 3.9 48.6 21.9 18.6 29.0 3.8 11.0 10.5 22.2 10.0 14.0 9.2 4.2 4.5 1.5 26.5 0.0 22.6 1.7 10.9 17.3 22.3 12.5 1.7 23.9 21.9 8.8 7.3 6.6 22.1 1.3 10.6 16.4 5.2 11.7 1.7 22.4 15.5 10.2 16.1 11.8 3.1 12.5 11.0 1.8 90.9 12.6 1.9 1.0 4.0 4.1 78.1 17.0 10.5 3.5 19.3 14.9 5.2 12.0 9.7 0.0 3.5 6.1 4.8 16.0 28.3 24.9 43.8 1.7 4.9 5.5 30.7 FGFR2 "BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25" ENSG00000066468 "Fibroblast growth factor receptor 2" P21802 10 121478332-121598458 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 273.8;choroid plexus: 198.1" "Group enriched" "Detected in many" 5 "Astrocytes: 228.2;Cholangiocytes: 213.1;Oligodendrocytes: 562.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 13.2;eosinophil: 3.8" "Lineage enriched" "Detected in single" 58 "granulocytes: 13.2" "Cell line enhanced" "Detected in many" "AN3-CA: 189.0;BEWO: 60.9;CACO-2: 49.6;HaCaT: 55.6;HAP1: 63.7;NTERA-2: 57.8;T-47d: 49.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010886, HPA035305" Uncertain Supported "Nucleoplasm,Vesicles,Cell Junctions" "Secreted - unknown location" NA NA 1200000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "Nucleoplasm, Vesicles" "CAB010886: AB_259379, HPA035305: AB_10672862" "unprognostic (5.53e-2)" "prognostic favorable (8.79e-4)" "unprognostic (1.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.32e-4)" "unprognostic (1.53e-1)" "unprognostic (4.96e-3)" "unprognostic (1.74e-1)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "unprognostic (2.54e-1)" "unprognostic (6.93e-2)" "unprognostic (2.25e-1)" 5.7 21.3 103.9 8.2 186.8 0.3 22.9 178.9 198.9 19.7 198.1 44.8 10.4 54.6 15.3 25.2 29.6 31.3 5.6 109.9 124.7 26.3 41.0 30.9 2.9 250.9 185.9 18.0 31.0 61.0 6.8 15.7 220.5 27.4 21.2 1.2 59.1 54.6 0.5 109.3 12.2 43.6 165.5 0.8 22.5 7.6 148.0 10.1 54.6 0.2 9.1 16.6 27.4 273.8 7.2 0.4 30.2 189.0 0.1 0.0 60.9 0.4 0.0 0.0 0.0 49.6 1.1 0.1 12.5 2.8 0.1 55.6 63.7 13.0 0.0 0.1 12.7 0.0 0.2 1.2 1.5 0.2 11.7 0.1 26.2 0.0 0.6 0.0 0.0 0.3 0.2 0.2 0.0 11.7 0.2 0.1 57.8 8.7 0.0 0.1 0.0 7.5 18.0 15.8 0.5 0.5 0.4 33.4 0.0 36.6 49.3 0.0 0.1 0.3 8.5 0.2 0.7 0.1 0.1 0.0 0.3 0.0 0.5 13.2 0.0 3.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 103.9 186.8 178.9 198.9 109.9 124.7 250.9 185.9 220.5 165.5 148.0 273.8 1.4 19.2 36.0 228.2 0.6 40.1 34.3 18.4 58.6 0.2 8.7 25.4 9.1 213.1 38.4 36.8 0.0 16.5 0.3 7.3 0.0 7.4 4.1 28.1 4.4 1.0 2.4 2.7 14.8 0.2 3.0 9.0 13.3 53.1 0.0 0.1 1.8 5.0 2.3 0.0 31.2 40.8 10.2 0.6 4.4 9.6 1.2 1.1 5.4 10.3 0.6 2.0 1.0 6.0 562.5 0.7 3.0 6.0 0.1 15.0 1.8 13.6 15.3 0.2 0.0 1.6 2.6 0.7 9.9 18.7 27.7 4.0 1.5 0.4 3.8 31.4 FGFRL1 ENSG00000127418 "Fibroblast growth factor receptor like 1" Q8N441 4 1009936-1026898 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 34.0;Granulosa cells: 30.9;Hepatocytes: 37.5;Muller glia cells: 94.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.1;non-classical monocyte: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-251 MG: 99.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026019, HPA068828" Approved Supported Vesicles No No "Cluster 7: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 5: Muller glia cells - Visual perception" Vesicles "CAB026019: , HPA068828: AB_2686043" "unprognostic (1.30e-2)" "unprognostic (2.54e-2)" "unprognostic (6.27e-2)" "unprognostic (2.80e-2)" "unprognostic (1.23e-2)" "unprognostic (1.48e-1)" "unprognostic (2.62e-2)" "unprognostic (9.79e-2)" "unprognostic (4.87e-3)" "unprognostic (8.46e-2)" "unprognostic (2.01e-2)" "unprognostic (1.51e-1)" "unprognostic (2.36e-3)" "unprognostic (1.49e-1)" "unprognostic (7.80e-2)" "unprognostic (1.06e-2)" "unprognostic (1.96e-2)" 38.1 56.0 40.8 5.0 43.3 7.6 24.1 40.6 49.5 15.7 29.8 10.2 7.3 9.9 3.4 5.5 36.0 9.3 19.8 39.2 33.5 25.4 52.8 15.1 3.1 49.9 45.8 25.4 71.6 16.1 21.6 3.0 46.5 12.4 4.9 10.5 37.6 2.7 20.6 10.7 13.5 4.0 42.2 9.1 27.2 5.5 47.9 1.4 67.1 9.6 2.2 11.2 8.0 42.1 23.2 31.6 11.3 34.3 11.9 12.3 2.9 40.4 6.2 12.9 8.4 23.1 47.9 2.6 49.3 63.3 58.3 5.8 21.8 14.1 11.8 8.3 21.0 0.3 41.2 61.5 24.0 13.7 5.6 25.7 11.7 22.4 9.5 48.4 12.5 9.3 25.3 8.9 7.9 30.8 16.0 37.7 14.2 39.7 83.8 24.7 16.3 16.7 22.6 3.6 1.2 2.2 38.1 0.8 15.2 13.4 22.5 11.9 26.1 68.8 27.2 35.2 99.8 8.9 12.9 3.8 18.1 15.6 22.8 0.6 0.0 0.0 0.2 1.1 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.1 40.8 43.3 40.6 49.5 39.2 33.5 49.9 45.8 46.5 42.2 47.9 42.1 3.8 3.2 4.1 34.0 2.8 6.5 3.7 5.4 2.2 5.4 13.2 6.1 8.5 11.5 6.9 7.3 0.0 1.6 4.1 4.4 0.0 9.6 0.2 6.0 4.2 2.6 1.8 4.8 3.2 10.2 26.6 5.1 6.6 13.5 1.3 30.9 5.3 37.5 3.2 0.0 2.8 11.0 0.0 1.6 2.5 1.2 4.4 3.4 7.2 1.9 1.3 94.0 1.0 5.0 5.4 19.9 2.7 3.4 2.2 11.4 2.9 7.6 7.0 5.6 0.0 3.3 5.1 0.4 4.2 1.2 4.7 1.5 4.2 17.5 3.6 8.8 FIG4 "ALS11, CMT4J, dJ249I4.1, hSac3, KIAA0274, SAC3" ENSG00000112367 "FIG4 phosphoinositide 5-phosphatase" Q92562 6 109690609-109878098 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 49.5;Oligodendrocyte precursor cells: 46.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017823, HPA068859" Approved Supported "Vesicles,Lipid droplets" NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Lipid droplets" "CAB017823: , HPA068859: AB_2686049" "prognostic unfavorable (5.91e-4)" "unprognostic (4.12e-2)" "prognostic favorable (8.42e-4)" "unprognostic (3.17e-2)" "unprognostic (1.66e-1)" "unprognostic (1.16e-1)" "prognostic unfavorable (4.73e-4)" "unprognostic (7.06e-2)" "unprognostic (2.69e-1)" "unprognostic (8.67e-2)" "unprognostic (3.44e-3)" "unprognostic (4.22e-2)" "prognostic favorable (8.19e-4)" "unprognostic (1.48e-1)" "unprognostic (2.02e-1)" "unprognostic (5.45e-2)" "unprognostic (2.00e-2)" 9.3 10.2 5.5 7.1 7.2 5.6 8.1 5.9 7.7 8.2 12.9 10.1 5.0 8.5 7.8 9.4 7.2 7.6 7.7 6.0 8.8 9.5 6.1 13.4 10.1 6.4 7.3 8.2 7.5 17.4 11.9 8.8 8.9 7.7 9.5 10.8 10.7 7.8 10.6 7.6 9.1 10.3 5.6 13.8 8.7 8.2 6.1 12.3 9.3 8.3 10.1 9.2 8.4 7.0 8.3 8.4 11.7 14.9 11.8 17.2 7.8 9.9 14.1 8.3 23.2 4.6 7.2 23.2 5.8 18.9 14.9 5.2 12.6 8.5 20.7 13.3 16.5 10.9 5.9 5.5 11.4 9.5 10.0 8.8 9.9 12.8 10.6 22.8 18.3 13.9 6.8 8.8 12.7 6.8 12.0 8.4 5.9 12.0 4.7 7.9 6.1 7.3 13.3 18.4 12.8 11.7 7.1 10.7 21.1 15.6 6.0 23.1 11.2 4.2 3.8 5.4 9.5 3.4 2.6 7.9 27.3 8.5 4.6 15.4 24.9 14.2 8.8 24.5 7.7 18.9 6.3 8.5 19.2 21.2 7.5 7.5 7.4 10.0 15.2 8.1 9.4 11.7 5.5 7.2 5.9 7.7 6.0 8.8 6.4 7.3 8.9 5.6 6.1 7.0 4.9 16.0 9.0 24.5 15.7 4.6 7.1 7.3 5.2 8.8 5.4 3.3 6.7 2.8 6.9 9.2 2.1 13.4 9.5 7.0 5.9 9.8 18.0 7.5 5.3 5.2 10.2 3.0 49.5 11.4 7.0 6.0 8.2 7.9 8.8 8.6 7.1 4.1 23.3 1.7 32.4 8.6 8.2 19.2 6.8 17.7 3.4 17.3 8.8 29.0 16.4 8.5 11.3 46.8 37.4 7.6 6.3 6.8 6.5 4.0 6.3 8.2 9.1 7.6 0.0 5.1 6.6 5.5 12.1 8.3 4.4 12.3 9.3 5.6 6.4 8.9 FIGN ENSG00000182263 "Fidgetin, microtubule severing factor" Q5HY92 2 163593396-163736012 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 161.3;Inhibitory neurons: 82.9;Oligodendrocyte precursor cells: 309.6;Oligodendrocytes: 129.4;Sertoli cells: 72.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 34 "basophil: 3.3" "Lineage enriched" "Detected in single" 34 "granulocytes: 3.3" "Cell line enhanced" "Detected in many" "AF22: 18.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034987, HPA057919" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane, Cytosol" "Vesicles, Cell Junctions" "HPA034987: AB_10669681, HPA057919: " "unprognostic (3.93e-2)" "unprognostic (8.30e-3)" "unprognostic (1.48e-1)" "unprognostic (7.68e-5)" "unprognostic (3.45e-2)" "unprognostic (8.98e-4)" "unprognostic (5.23e-3)" "unprognostic (7.65e-3)" "unprognostic (2.33e-1)" "unprognostic (1.64e-1)" "unprognostic (2.07e-2)" "unprognostic (3.24e-2)" "unprognostic (3.85e-3)" "unprognostic (3.22e-2)" "unprognostic (2.69e-1)" "unprognostic (4.10e-2)" "unprognostic (3.78e-2)" 3.1 2.0 3.9 0.4 5.0 0.8 2.0 2.3 4.4 2.4 0.0 2.6 0.4 1.1 1.2 0.6 1.9 1.1 3.3 2.5 5.4 1.9 3.2 1.4 0.6 3.0 4.2 4.6 2.9 0.4 2.6 1.1 3.9 1.6 0.7 1.4 2.6 2.7 1.0 1.0 1.4 0.9 1.8 3.0 1.8 1.1 4.6 0.2 1.1 1.7 0.2 1.7 2.4 5.1 6.4 2.3 18.6 0.0 0.0 0.0 6.8 2.4 1.6 1.7 3.2 0.0 2.2 0.0 6.6 2.6 3.4 0.9 6.2 2.6 1.3 0.0 4.6 0.0 4.7 4.6 1.5 0.0 0.0 0.8 2.2 3.3 9.0 2.6 4.0 0.0 0.0 0.0 5.1 1.6 0.0 0.0 7.9 0.4 2.9 0.0 6.3 0.0 4.2 2.1 2.9 2.5 0.0 1.8 1.7 10.3 2.0 0.0 0.4 7.6 6.8 0.0 5.1 1.1 0.0 0.0 2.3 0.0 4.3 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 5.0 2.3 4.4 2.5 5.4 3.0 4.2 3.9 1.8 4.6 5.1 2.9 6.4 7.3 161.3 0.7 1.9 0.1 2.8 1.8 24.4 5.7 2.7 19.4 20.0 3.0 12.9 0.0 21.2 0.2 0.1 1.9 3.7 3.8 0.7 0.7 2.1 0.0 0.0 53.4 1.5 7.4 11.6 4.1 1.6 0.0 23.6 7.9 13.5 1.4 6.7 82.9 0.0 4.1 0.0 1.6 6.4 51.9 0.6 17.8 28.1 0.0 4.3 0.0 309.6 129.4 1.1 0.0 34.3 0.0 1.8 0.0 8.1 4.0 2.1 72.3 16.6 17.8 1.1 1.2 1.0 0.4 16.8 0.2 7.0 0.0 0.0 FJX1 "FLJ22416, FLJ25593" ENSG00000179431 "Four-jointed box kinase 1" Q86VR8 11 35618460-35620865 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 29.0;Cytotrophoblasts: 25.6;Endometrial ciliated cells: 30.6;Endometrial stromal cells: 35.4;Granulosa cells: 31.2" "Cancer enhanced" "Detected in all" "glioma: 34.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-251 MG: 60.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059220 Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA059220: AB_2683950" "unprognostic (8.99e-2)" "unprognostic (1.90e-1)" "unprognostic (1.65e-3)" "unprognostic (5.20e-2)" "unprognostic (5.72e-2)" "unprognostic (9.56e-3)" "unprognostic (5.16e-2)" "unprognostic (1.06e-2)" "unprognostic (1.74e-1)" "unprognostic (4.39e-3)" "unprognostic (5.28e-2)" "unprognostic (2.02e-1)" "prognostic unfavorable (9.24e-9)" "unprognostic (1.64e-2)" "unprognostic (9.64e-2)" "unprognostic (8.35e-2)" "prognostic unfavorable (6.56e-4)" 8.9 5.9 8.4 1.7 10.4 0.1 3.5 6.8 9.2 7.8 4.4 2.1 0.3 5.2 1.5 3.8 4.9 2.3 2.5 10.2 7.1 9.5 2.2 2.8 1.1 8.2 13.1 9.2 3.5 0.6 2.3 3.4 6.6 5.2 0.2 0.7 2.5 2.2 1.1 6.0 1.3 1.6 9.6 5.0 1.6 0.7 12.0 1.0 2.9 0.3 1.7 3.8 3.3 10.1 23.3 11.4 12.0 3.8 4.1 12.6 3.7 25.4 17.3 24.1 17.2 14.5 7.1 0.0 5.7 10.2 49.6 24.3 4.2 42.6 20.4 0.3 33.0 2.1 4.4 0.6 9.7 2.7 0.1 4.8 31.8 12.7 38.1 3.9 11.1 1.2 12.5 0.1 23.6 5.4 0.8 0.0 16.4 0.1 33.6 1.4 26.6 5.4 18.6 28.5 11.2 6.4 2.7 2.1 7.5 8.7 48.2 0.5 21.7 19.0 35.5 3.7 60.9 0.0 0.0 0.0 33.9 1.1 28.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 10.4 6.8 9.2 10.2 7.1 8.2 13.1 6.6 9.6 12.0 10.1 7.8 0.0 0.0 9.4 0.2 17.5 15.8 14.0 29.0 1.8 5.3 13.3 1.2 0.0 3.9 0.0 12.5 25.6 0.0 0.1 1.9 7.6 0.3 30.6 35.4 11.8 0.0 0.0 6.6 0.2 13.9 7.2 0.0 6.5 0.0 31.2 17.9 0.4 3.6 0.0 3.9 0.0 2.0 0.6 1.7 0.1 0.6 1.1 0.0 1.0 0.0 12.5 0.0 6.6 1.7 1.4 0.0 0.7 0.0 22.9 0.0 8.0 4.3 0.5 0.0 6.0 22.3 0.6 1.0 5.6 9.5 11.9 0.4 3.1 0.0 2.5 FKBP1B "FKBP12.6, FKBP1L, FKBP9, OTK4, PPIase" ENSG00000119782 "FKBP prolyl isomerase 1B" P68106 2 24049701-24063681 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 47.9" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 49.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.2;T-reg: 2.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 47.9;NTERA-2: 42.9;SH-SY5Y: 30.7;SuSa: 46.1;TIME: 38.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045572, HPA051798" Uncertain Approved Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "HPA045572: AB_2732521, HPA051798: AB_2681615" "unprognostic (3.01e-3)" "unprognostic (3.35e-1)" "unprognostic (7.05e-2)" "unprognostic (9.89e-3)" "unprognostic (1.47e-2)" "unprognostic (2.10e-1)" "unprognostic (2.23e-2)" "unprognostic (9.19e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-1)" "unprognostic (9.55e-2)" "unprognostic (1.08e-1)" "unprognostic (1.12e-1)" "unprognostic (7.53e-2)" "unprognostic (3.43e-2)" "unprognostic (2.85e-2)" "unprognostic (1.45e-1)" 5.6 4.4 32.5 2.2 36.1 1.6 5.5 26.5 47.9 6.7 23.0 7.1 19.6 4.8 2.7 8.3 3.9 5.4 5.1 39.2 30.9 8.7 6.6 10.5 1.5 27.7 27.6 5.5 7.5 7.0 6.4 4.0 30.3 7.2 3.3 7.7 6.6 6.3 1.4 6.5 6.8 2.7 25.9 2.8 15.0 1.6 32.7 1.6 6.7 1.2 2.3 5.6 8.1 30.5 0.2 2.0 17.2 0.0 10.9 4.7 6.2 5.8 6.0 2.5 3.6 1.2 2.0 0.0 4.3 10.3 15.4 6.8 25.7 20.2 1.6 3.0 16.1 6.0 0.2 47.9 4.5 0.0 14.1 3.9 4.6 5.9 1.1 14.7 16.5 6.8 1.5 0.1 5.9 0.2 2.0 0.0 42.9 1.7 3.0 3.1 1.5 0.2 2.0 1.3 4.1 30.7 0.3 0.1 5.8 46.1 1.2 2.2 38.0 0.0 5.2 0.2 1.4 1.1 0.5 0.0 6.4 0.0 1.3 0.4 0.4 2.2 0.1 0.4 0.0 0.1 0.2 0.2 1.0 1.2 0.0 0.1 0.0 0.1 0.0 0.2 2.8 0.5 32.5 36.1 26.5 47.9 39.2 30.9 27.7 27.6 30.3 25.9 32.7 30.5 9.3 0.0 6.8 2.9 1.8 9.2 14.0 13.7 11.4 2.1 6.5 13.7 0.9 22.8 4.7 7.3 0.0 4.9 2.7 15.8 13.7 27.6 0.6 3.5 5.0 10.9 9.5 7.0 16.9 38.2 31.9 6.9 16.3 7.1 1.3 3.4 15.7 10.2 7.5 1.7 7.8 8.9 2.0 4.0 17.4 2.9 2.8 9.1 28.4 4.7 13.0 31.4 1.0 2.5 1.3 49.8 25.4 4.1 2.4 15.5 10.6 6.8 2.0 3.6 26.3 2.9 10.6 1.6 5.4 9.1 7.4 5.2 4.9 1.4 4.5 19.3 FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FKBP prolyl isomerase 9" O95302 7 32957404-33006930 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 108.6;Fibroblasts: 89.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 379.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012595, HPA055256" Approved Approved "Golgi apparatus,Vesicles,Mitochondria" "Intracellular and membrane" No No 63000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Mitochondria" Vesicles "HPA012595: AB_1848629, HPA055256: AB_2682761" "unprognostic (1.23e-2)" "prognostic unfavorable (4.22e-4)" "unprognostic (6.94e-2)" "unprognostic (6.25e-3)" "prognostic unfavorable (5.80e-4)" "prognostic unfavorable (2.02e-4)" "prognostic unfavorable (8.69e-4)" "unprognostic (3.40e-2)" "unprognostic (9.59e-2)" "unprognostic (2.58e-1)" "unprognostic (3.63e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-2)" "unprognostic (6.31e-2)" "unprognostic (1.97e-1)" "unprognostic (8.90e-3)" "prognostic unfavorable (7.02e-6)" 80.7 44.8 23.9 16.8 24.0 2.3 59.1 26.5 25.3 65.9 28.1 44.8 19.7 55.7 22.4 35.6 50.6 44.4 77.1 21.4 32.1 38.2 21.1 49.6 13.6 28.9 30.2 46.3 40.8 25.1 34.8 77.4 29.3 42.3 45.3 11.7 36.0 52.1 35.0 64.4 31.0 74.4 28.0 23.7 41.0 11.4 34.2 8.2 40.8 49.7 15.8 43.3 52.2 27.9 38.9 71.4 27.6 113.4 254.1 290.2 36.4 202.6 209.9 65.5 103.9 31.6 89.2 0.2 80.7 379.5 105.1 73.3 40.8 100.0 75.2 0.1 11.9 6.6 72.3 31.6 105.6 0.4 10.8 191.8 59.6 59.0 56.9 156.3 83.9 0.1 15.0 7.7 137.3 37.1 0.2 19.4 5.8 76.6 37.3 0.3 73.7 0.3 73.0 13.0 25.7 62.4 115.6 58.4 73.4 69.6 41.1 18.7 112.8 107.0 99.8 67.4 46.8 23.9 48.9 0.2 104.4 0.3 218.5 0.9 2.2 0.5 0.0 1.6 0.0 0.2 0.0 0.0 0.8 0.1 0.1 0.0 4.0 0.1 0.4 0.1 0.0 0.6 23.9 24.0 26.5 25.3 21.4 32.1 28.9 30.2 29.3 28.0 34.2 27.9 108.6 12.8 21.7 22.9 0.6 34.3 12.7 31.4 10.2 8.2 15.7 16.5 46.1 17.2 10.3 18.4 10.4 18.8 0.6 23.2 5.9 19.5 0.5 22.6 25.8 80.1 12.2 1.7 9.8 41.5 27.7 89.1 17.9 23.0 5.7 81.0 60.0 18.0 7.6 11.8 10.2 25.4 10.2 8.6 23.5 3.2 36.7 5.4 60.5 15.0 2.9 30.5 0.0 8.5 8.8 36.5 22.1 55.3 4.4 8.1 18.8 8.1 11.0 5.2 46.0 21.2 45.8 1.0 1.3 12.1 28.6 13.1 3.1 12.3 27.7 10.5 FLOT1 ENSG00000137312 "Flotillin 1" O75955 6 30727709-30742732 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 314.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 423.3;hTERT-RPE1: 242.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001393, CAB007766" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA 160000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "Vesicles, Plasma membrane" "CAB007766: AB_562116, HPA001393: AB_1078892" "unprognostic (2.68e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (5.78e-4)" "unprognostic (1.78e-2)" "unprognostic (2.21e-1)" "unprognostic (3.41e-3)" "unprognostic (2.68e-3)" "unprognostic (1.86e-1)" "unprognostic (2.65e-1)" "prognostic favorable (3.06e-4)" "unprognostic (1.81e-2)" "unprognostic (9.36e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (6.43e-3)" "unprognostic (3.92e-1)" "unprognostic (1.61e-2)" "unprognostic (2.46e-2)" 141.7 239.5 49.3 27.9 54.6 41.7 129.8 49.4 60.9 111.1 56.8 150.3 28.7 108.9 8.4 81.8 95.8 23.1 234.5 55.1 57.9 146.1 127.3 136.8 22.1 50.9 51.5 84.1 88.5 41.4 102.5 35.0 57.4 109.6 17.7 6.3 99.1 45.8 190.0 51.7 87.1 33.0 45.8 129.6 96.9 65.0 53.6 24.9 111.7 83.1 17.0 134.5 96.9 48.8 54.3 18.3 46.4 62.0 49.1 71.0 1.3 59.7 67.5 82.8 79.3 19.4 30.0 13.0 29.0 101.3 423.3 41.8 35.0 20.1 28.6 36.1 1.3 41.1 17.5 19.1 119.2 12.2 67.0 75.4 30.6 40.9 71.3 242.7 65.9 37.9 21.7 52.7 77.9 22.9 38.0 14.5 15.1 29.4 15.7 20.2 48.4 38.0 30.3 13.0 16.4 17.2 33.7 28.7 164.6 30.4 43.8 10.1 44.0 199.5 37.6 20.6 120.6 18.6 19.7 28.8 26.2 42.6 122.7 179.3 76.9 132.0 35.0 38.9 24.1 28.0 21.3 30.4 58.9 23.0 23.7 27.4 314.3 79.9 26.3 59.2 3.9 58.3 49.3 54.6 49.4 60.9 55.1 57.9 50.9 51.5 57.4 45.8 53.6 48.8 175.4 89.8 77.0 26.1 38.1 28.7 111.5 44.9 80.2 14.7 72.1 73.4 90.6 62.9 59.2 84.6 6.2 82.2 57.7 103.2 123.3 77.6 60.2 73.9 50.1 141.6 68.8 41.7 41.3 85.9 70.7 67.6 55.5 75.2 143.3 41.4 154.9 59.7 130.6 20.2 40.2 66.6 57.0 61.3 84.9 144.1 61.8 89.4 71.2 28.1 99.2 64.7 68.0 27.2 22.7 65.7 112.0 38.0 60.4 69.5 89.0 172.1 80.7 18.1 52.6 58.1 65.9 80.2 26.7 63.7 26.9 61.6 51.2 29.1 83.2 99.4 FLOT2 "ECS-1, ECS1, ESA, ESA1, M17S1" ENSG00000132589 "Flotillin 2" Q14254 17 28879335-28897733 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001396, CAB004395, HPA071038" Supported Supported "Vesicles,Plasma membrane" NA NA 170000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" Vesicles "CAB004395: AB_627618, HPA001396: AB_1078894, HPA071038: " "unprognostic (6.04e-2)" "unprognostic (8.76e-3)" "unprognostic (3.01e-1)" "unprognostic (8.92e-2)" "unprognostic (4.15e-3)" "unprognostic (2.17e-2)" "unprognostic (4.36e-3)" "unprognostic (2.12e-1)" "unprognostic (5.21e-2)" "unprognostic (1.20e-1)" "unprognostic (9.98e-2)" "unprognostic (2.80e-1)" "unprognostic (4.12e-3)" "unprognostic (2.64e-2)" "unprognostic (1.09e-1)" "unprognostic (1.11e-3)" "unprognostic (2.20e-2)" 60.2 46.4 38.4 56.8 38.6 97.1 56.2 28.1 47.6 42.8 45.2 58.9 21.0 39.1 21.2 69.3 46.8 27.0 63.5 41.1 42.5 71.4 98.4 59.5 68.2 45.9 37.1 37.7 38.8 30.0 22.3 58.4 41.3 67.8 27.2 20.3 61.7 51.6 51.6 38.2 53.0 35.3 37.5 122.7 44.6 10.4 47.1 47.8 39.6 44.1 63.6 78.8 49.6 36.1 55.5 90.8 69.6 60.2 33.6 44.2 76.6 42.5 57.9 60.9 71.3 96.0 45.7 76.9 79.3 47.6 42.0 63.3 76.5 69.7 25.9 245.5 91.4 92.7 80.5 70.3 43.6 76.8 15.2 53.3 53.6 49.3 66.9 64.1 97.4 21.8 89.0 65.6 28.9 83.5 21.2 54.0 61.4 48.6 24.6 32.6 70.6 189.3 92.0 166.9 61.9 103.3 99.8 69.6 77.5 66.7 72.3 136.3 81.5 21.4 38.2 35.2 65.0 36.5 68.2 39.5 59.9 72.3 40.7 171.9 106.0 213.2 98.8 96.6 72.6 98.5 74.6 84.5 144.3 118.1 55.3 69.0 415.2 78.5 110.2 38.8 97.6 143.2 38.4 38.6 28.1 47.6 41.1 42.5 45.9 37.1 41.3 37.5 47.1 36.1 34.2 22.4 21.9 12.7 46.8 12.6 27.1 20.6 29.6 6.9 24.9 30.1 32.9 22.8 16.5 20.2 10.4 96.6 20.5 29.0 15.6 39.3 13.0 25.8 13.2 37.0 25.8 49.2 17.0 31.1 68.9 14.8 23.0 27.6 6.3 15.6 48.9 45.1 44.4 5.0 19.2 25.9 10.2 43.3 22.6 42.3 10.8 31.1 8.8 22.5 75.2 10.7 35.0 16.1 11.0 32.2 16.5 8.6 27.8 14.8 14.8 26.7 19.1 12.4 19.7 7.1 13.4 1.6 6.9 42.4 9.2 37.1 32.5 4.2 32.0 26.7 FMNL3 "DKFZp762B245, MGC45819, WBP3" ENSG00000161791 "Formin like 3" Q8IVF7 12 49636499-49708165 "Predicted intracellular proteins" Angiogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 35.8;Cone photoreceptor cells: 39.6;dendritic cells: 48.6;Microglial cells: 119.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 47.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002552, HPA023201" Uncertain Supported "Golgi apparatus,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Vesicles, Plasma membrane" Cytosol "HPA002552: AB_1078862, HPA023201: AB_1848575" "unprognostic (2.97e-1)" "unprognostic (2.77e-3)" "unprognostic (4.97e-3)" "unprognostic (7.19e-2)" "unprognostic (5.42e-2)" "unprognostic (2.33e-3)" "unprognostic (5.37e-3)" "unprognostic (1.52e-2)" "unprognostic (2.83e-1)" "unprognostic (1.54e-1)" "unprognostic (6.67e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (3.58e-5)" "unprognostic (1.04e-1)" "unprognostic (2.31e-1)" "unprognostic (2.03e-1)" "unprognostic (2.69e-2)" 12.2 5.7 13.7 20.5 13.2 5.2 10.6 13.0 11.2 9.6 3.0 8.0 5.7 11.2 19.2 4.5 6.9 11.1 12.6 11.0 12.6 9.3 2.7 17.4 23.5 21.7 14.6 16.1 3.2 3.6 4.1 14.0 18.2 6.0 5.6 2.7 4.6 4.4 5.6 4.4 10.2 11.5 17.7 13.4 6.6 10.1 20.4 20.1 13.4 6.7 28.3 8.6 6.3 20.4 8.6 2.5 18.4 6.1 5.0 20.1 0.2 10.4 21.0 13.8 12.1 9.7 2.3 18.2 19.5 12.4 15.2 0.4 9.5 4.3 12.6 16.2 3.6 20.1 2.9 0.5 8.8 4.0 25.1 12.7 0.7 21.7 9.1 41.2 37.1 9.0 4.6 13.0 20.5 6.3 16.6 6.0 6.0 0.9 5.5 7.9 23.0 2.8 13.1 1.3 3.0 8.6 6.0 0.8 11.8 9.3 1.5 5.9 47.2 34.2 11.8 0.6 18.2 6.7 0.4 9.8 21.3 12.4 14.7 3.0 0.1 0.8 0.8 0.4 0.4 0.2 0.3 0.5 0.2 1.1 0.4 0.5 0.0 0.6 0.3 5.1 0.1 0.5 13.7 13.2 13.0 11.2 11.0 12.6 21.7 14.6 18.2 17.7 20.4 20.4 35.8 3.2 3.4 6.8 17.5 1.7 0.7 0.4 2.2 11.3 1.3 2.3 3.3 0.0 1.4 1.8 39.6 2.1 48.6 0.1 0.0 0.3 2.0 0.7 2.6 29.7 0.0 1.7 16.0 0.6 0.8 7.1 1.5 2.0 27.8 5.4 15.7 0.8 11.1 3.3 6.5 0.8 0.0 6.9 9.0 4.6 3.7 17.7 5.4 119.0 22.9 0.5 16.5 27.6 5.5 0.8 0.1 6.4 1.8 0.8 0.0 0.2 0.2 2.0 13.1 15.5 10.3 5.9 7.5 0.4 1.4 2.5 13.6 2.6 0.1 0.4 FMO4 FMO2 ENSG00000076258 "Flavin containing dimethylaniline monoxygenase 4" P31512 1 171314183-171342084 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 48.6;liver: 61.3" "Cell type enhanced" "Detected in many" "Distal tubular cells: 29.4;Hepatocytes: 22.1;Oligodendrocytes: 18.5;Proximal enterocytes: 16.5;Proximal tubular cells: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 5.7;HSkMC: 6.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049100, HPA072438" Approved Approved Vesicles,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "HPA049100: AB_2680629, HPA072438: " "unprognostic (1.83e-2)" "unprognostic (1.17e-1)" "unprognostic (6.18e-2)" "unprognostic (3.01e-2)" "unprognostic (8.27e-2)" "unprognostic (4.13e-1)" "prognostic favorable (1.09e-4)" "prognostic favorable (7.45e-4)" "unprognostic (3.12e-2)" "unprognostic (2.15e-1)" "unprognostic (5.99e-2)" "unprognostic (2.90e-1)" "prognostic favorable (6.96e-4)" "unprognostic (1.03e-1)" "unprognostic (1.69e-1)" "unprognostic (7.45e-3)" "unprognostic (1.95e-1)" 3.7 2.6 2.2 1.9 3.1 0.9 4.1 2.8 3.0 3.3 3.1 5.0 5.4 2.7 6.3 2.3 3.5 4.9 5.2 2.1 2.6 48.6 61.3 3.2 2.9 3.1 2.8 3.8 2.4 4.7 1.9 2.3 3.3 3.1 4.8 0.7 2.0 2.2 1.0 3.4 9.2 2.0 2.6 3.1 5.0 1.7 3.1 3.6 3.2 2.1 3.3 2.4 2.9 3.5 0.1 0.1 0.3 0.4 4.1 3.4 0.2 0.8 3.7 1.1 1.2 0.6 5.3 3.7 5.7 0.1 2.0 0.2 0.7 1.0 1.6 1.6 0.8 0.0 0.0 0.0 0.6 0.7 0.8 6.6 2.4 0.4 1.0 0.4 0.2 1.7 0.2 2.3 0.5 0.7 1.6 1.3 0.4 0.9 1.2 0.4 0.4 2.1 2.6 0.0 0.1 0.0 1.2 1.0 2.4 4.1 2.2 1.0 0.1 0.9 0.3 1.0 0.7 2.9 1.0 2.2 1.8 1.1 0.8 0.2 1.0 0.3 0.9 1.6 0.7 1.2 0.8 1.3 0.9 1.8 1.2 0.9 0.1 1.7 1.1 1.2 2.1 0.8 2.2 3.1 2.8 3.0 2.1 2.6 3.1 2.8 3.3 2.6 3.1 3.5 2.2 0.0 2.6 7.2 3.2 2.8 4.6 5.0 2.8 0.0 2.3 2.0 3.7 2.8 3.7 9.2 0.0 2.8 0.6 7.1 29.4 2.3 5.7 3.8 1.7 1.4 1.2 0.0 0.1 1.4 1.2 6.6 8.2 1.7 1.3 1.5 2.9 22.1 3.7 0.0 0.1 3.2 2.0 5.9 1.3 1.3 1.5 2.7 5.4 2.8 1.6 1.8 1.0 0.0 18.5 1.1 0.7 0.4 1.1 0.9 16.5 49.5 7.3 0.0 0.0 1.8 2.1 0.3 0.5 1.9 1.6 1.9 1.7 2.0 2.8 1.8 FNBP1 "FBP17, KIAA0554" ENSG00000187239 "Formin binding protein 1" Q96RU3 9 129887187-130043194 "Disease related genes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 317.7;Langerhans cells: 402.9;monocytes: 433.2;Oligodendrocytes: 522.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 137.7;JURKAT: 143.2;MOLT-4: 140.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019635, HPA019691, HPA022119, HPA067742" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Plasma membrane" Vesicles "HPA019635: AB_2732423, HPA019691: AB_2670231, HPA022119: AB_2670897, HPA067742: " "unprognostic (2.86e-1)" "unprognostic (2.59e-3)" "unprognostic (1.22e-2)" "unprognostic (2.10e-1)" "unprognostic (3.20e-1)" "unprognostic (1.43e-2)" "unprognostic (6.30e-3)" "unprognostic (9.10e-2)" "unprognostic (2.90e-1)" "unprognostic (6.17e-2)" "unprognostic (9.26e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (8.45e-5)" "unprognostic (6.84e-2)" "unprognostic (1.37e-1)" "unprognostic (2.10e-1)" "unprognostic (1.21e-1)" 21.8 11.9 51.2 57.8 73.7 40.6 16.4 77.4 53.4 32.5 22.2 107.3 15.0 50.0 17.0 39.4 34.8 27.8 15.1 47.0 62.5 16.4 18.4 25.4 78.1 67.6 69.1 22.1 8.1 10.7 17.7 16.3 65.8 41.4 29.6 12.6 16.3 44.1 24.1 25.9 37.6 46.8 55.9 60.9 29.6 17.3 69.9 111.0 33.4 13.2 74.3 68.4 26.8 86.6 42.5 19.3 34.9 40.8 21.0 25.8 29.5 23.7 20.2 17.6 14.7 20.3 16.2 82.9 20.4 44.5 20.8 20.7 33.0 21.6 17.6 137.7 9.8 22.8 22.8 13.8 35.8 62.3 75.1 18.7 9.3 32.6 19.5 25.6 26.1 143.2 5.4 1.1 16.4 34.0 140.1 60.8 27.5 5.7 32.6 31.9 28.3 24.1 22.1 23.0 5.5 17.6 43.3 42.9 16.5 33.3 30.0 28.3 31.9 16.6 20.7 30.5 15.0 16.4 64.4 3.8 20.0 42.2 25.2 13.2 5.1 9.6 10.8 5.6 9.3 12.7 9.7 10.3 5.8 7.7 8.9 8.6 9.3 6.0 6.5 6.9 10.9 4.5 51.2 73.7 77.4 53.4 47.0 62.5 67.6 69.1 65.8 55.9 69.9 86.6 27.2 35.3 25.2 317.7 180.4 33.1 21.3 12.8 21.6 20.2 42.5 24.6 14.8 15.7 29.8 22.0 52.1 18.6 217.2 28.3 19.6 22.6 1.7 46.2 38.8 38.3 18.1 31.3 65.6 17.3 24.5 38.8 26.5 78.7 80.4 9.2 71.0 18.4 43.6 28.6 107.8 8.7 20.3 221.2 402.9 5.5 46.6 131.1 76.5 95.5 433.2 42.8 223.5 69.4 522.1 21.8 19.8 51.6 147.9 67.8 0.2 15.0 42.3 29.5 59.2 19.9 41.0 26.5 45.4 26.7 41.1 63.9 233.7 7.1 16.2 42.3 FNDC11 "C20orf195, MGC5356" ENSG00000125531 "Fibronectin type III domain containing 11" Q9BVV2 20 63547891-63556695 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 45 "testis: 108.0" "Cell type enhanced" "Detected in some" "Club cells: 1.3;Collecting duct cells: 1.8;Endometrial ciliated cells: 5.1;Respiratory ciliated cells: 6.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "memory B-cell: 1.5;naive B-cell: 3.3" "Lineage enriched" "Detected in single" 7 "B-cells: 3.3" "Cell line enhanced" "Detected in some" "CAPAN-2: 5.2;EFO-21: 2.6;HaCaT: 1.5;OE19: 1.8;SH-SY5Y: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA041341 Approved Nucleoplasm,Vesicles,Aggresome NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 83: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Vesicles" Aggresome "HPA041341: AB_10794991" "unprognostic (2.01e-1)" "unprognostic (6.63e-2)" "unprognostic (6.06e-2)" "unprognostic (1.26e-1)" "unprognostic (1.51e-2)" "unprognostic (1.15e-1)" "unprognostic (2.36e-1)" "unprognostic (9.99e-3)" "unprognostic (7.94e-2)" "unprognostic (8.30e-4)" "unprognostic (3.68e-1)" "unprognostic (8.33e-2)" "unprognostic (3.56e-2)" "unprognostic (1.18e-1)" "unprognostic (1.05e-1)" "unprognostic (3.75e-1)" "unprognostic (6.81e-2)" 0.4 0.1 0.2 0.3 0.1 0.5 0.6 0.1 0.3 0.8 0.3 0.3 0.1 0.4 2.3 0.2 1.2 0.3 0.2 0.1 1.1 1.2 0.1 0.9 0.6 0.5 0.5 0.4 0.1 0.0 0.9 0.1 0.3 0.6 0.0 0.0 0.4 0.1 0.1 0.4 0.6 0.0 0.4 1.0 0.4 108.0 0.5 0.3 0.5 0.0 0.4 0.7 0.6 0.2 0.2 0.0 0.9 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.0 0.0 5.2 0.3 2.6 0.0 0.1 1.5 0.1 0.1 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.6 0.0 0.1 0.4 0.0 0.0 0.5 0.0 0.4 0.0 0.0 0.5 0.0 0.1 0.1 1.8 0.4 0.0 0.0 0.0 0.9 0.0 0.2 3.3 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.5 0.0 0.0 0.0 1.5 0.1 0.2 0.0 3.3 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.1 0.1 0.3 0.1 1.1 0.5 0.5 0.3 0.4 0.5 0.2 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.0 0.0 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 5.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.2 6.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 FO393400.1 ENSG00000285382 "Novel protein" 20 32632183-32743567 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 1.8;choroid plexus: 1.0;retina: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "HEL: 4.6" HPA054119 Approved Vesicles NA NA "Cluster 36: HEL - Hemostasis" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA054119: AB_2682388" 0.0 0.0 1.4 0.0 1.4 0.0 0.1 1.5 1.8 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 1.5 0.1 0.3 0.0 0.0 1.4 1.4 0.0 0.1 0.0 0.0 1.5 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.4 1.5 1.8 1.3 1.5 1.4 1.4 1.5 1.3 1.5 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FOSB "AP-1, DKFZp686C0818, G0S3, GOS3, GOSB, MGC42291" ENSG00000125740 "FosB proto-oncogene, AP-1 transcription factor subunit" P53539 19 45467995-45475179 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast glandular cells: 1627.1;Skeletal myocytes: 2234.0" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 45.6" "Immune cell enhanced" "Detected in some" "neutrophil: 4.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "GAMG: 11.4;HMC-1: 13.3;hTCEpi: 8.1;Karpas-707: 6.8;SK-BR-3: 9.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB010267, HPA054663" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Vesicles "CAB010267: AB_640583, HPA054663: AB_2682562" "unprognostic (7.22e-2)" "unprognostic (9.74e-2)" "unprognostic (2.91e-1)" "unprognostic (3.04e-1)" "unprognostic (1.08e-2)" "unprognostic (2.50e-1)" "unprognostic (1.30e-3)" "unprognostic (9.43e-2)" "unprognostic (2.04e-2)" "unprognostic (2.99e-2)" "unprognostic (2.50e-1)" "unprognostic (1.40e-1)" "unprognostic (3.51e-2)" "unprognostic (4.99e-3)" "unprognostic (8.72e-2)" "unprognostic (4.45e-2)" "unprognostic (4.04e-2)" 394.7 121.6 2.1 118.4 5.5 433.8 91.7 35.7 45.6 150.3 4.8 37.6 24.8 46.6 3.9 187.7 404.1 347.1 48.9 11.1 7.8 34.7 85.5 113.5 67.7 1.5 1.6 274.4 126.3 46.2 27.3 57.8 1.5 118.5 78.4 10.7 76.8 29.6 3.3 267.8 63.1 353.7 0.8 21.8 104.4 8.8 1.2 152.2 316.0 81.3 1.6 213.9 11.0 3.8 0.4 0.6 0.1 0.3 1.2 0.3 1.8 2.3 1.0 0.7 0.7 0.5 1.0 2.0 0.4 1.5 11.4 0.8 0.5 1.6 0.5 0.3 0.7 0.6 0.8 0.4 0.8 1.1 13.3 0.5 8.1 1.7 1.9 0.4 0.9 2.3 0.8 6.8 0.2 0.2 0.2 1.2 0.4 1.0 0.4 0.5 0.1 1.4 0.6 1.3 3.1 0.4 1.4 9.6 1.2 1.9 0.5 0.8 0.1 0.5 0.6 1.1 0.7 5.1 0.8 0.5 1.1 0.8 1.3 0.9 1.2 1.0 0.2 0.1 0.4 0.0 0.2 0.1 1.0 0.1 0.0 0.0 4.5 0.1 0.0 0.0 0.1 0.1 2.1 5.5 35.7 45.6 11.1 7.8 1.5 1.6 1.5 0.8 1.2 3.8 1048.7 685.9 761.3 2.6 445.7 380.5 533.4 162.4 865.6 50.6 1627.1 1523.2 177.8 370.3 174.4 11.0 135.5 237.5 359.6 551.1 1.9 145.5 10.1 667.9 1204.4 442.6 877.0 68.6 1.3 74.2 301.9 788.2 911.3 1541.3 830.4 239.3 393.7 77.9 210.3 8.4 0.3 898.4 42.7 345.2 353.4 11.3 240.2 797.3 172.5 1.0 16.3 186.1 1.0 0.0 0.3 111.6 457.3 59.5 503.4 307.3 417.8 2.7 111.5 217.6 302.4 2234.0 608.8 3.3 4.5 476.3 380.9 396.9 481.8 174.2 616.5 208.5 FOXI1 "FKHL10, FREAC6" ENSG00000168269 "Forkhead box I1" Q12951 5 170105897-170109734 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "kidney: 44.0;salivary gland: 11.4" "Cell type enriched" "Detected in some" 4 "Ionocytes: 132.2" "Group enriched" "Detected in many" 7 "breast cancer: 5.8;renal cancer: 23.1" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "eosinophil: 1.5" "Lineage enriched" "Detected in single" 16 "granulocytes: 1.5" "Group enriched" "Detected in some" 5 "MCF7: 1.4;SuSa: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA071469 Enhanced Supported Nucleoli,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli Vesicles "HPA071469: AB_2686403" "unprognostic (3.06e-1)" "unprognostic (1.24e-1)" "unprognostic (2.09e-1)" "unprognostic (2.48e-2)" "unprognostic (8.06e-2)" "unprognostic (7.47e-2)" "unprognostic (2.73e-1)" "unprognostic (1.52e-2)" "unprognostic (9.71e-3)" "unprognostic (4.88e-3)" "unprognostic (6.20e-2)" "unprognostic (1.34e-2)" "unprognostic (2.22e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 44.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.5 0.1 0.0 0.1 3.0 0.0 0.0 11.4 1.5 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.5 0.2 0.0 0.0 7.6 6.5 0.3 0.0 0.3 1.8 0.0 0.0 0.1 0.0 27.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 132.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.0 0.2 0.0 0.0 0.0 FOXJ3 KIAA1041 ENSG00000198815 "Forkhead box J3" Q9UPW0 1 42176539-42335877 "Predicted intracellular proteins, Transcription factors" "Differentiation, Meiosis, Spermatogenesis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 126.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067284 Approved "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nuclear speckles" Vesicles "HPA067284: AB_2685817" "unprognostic (5.60e-2)" "unprognostic (2.26e-2)" "unprognostic (4.24e-2)" "unprognostic (5.15e-2)" "unprognostic (3.18e-2)" "unprognostic (1.56e-2)" "prognostic unfavorable (5.17e-6)" "unprognostic (3.65e-3)" "unprognostic (1.17e-1)" "unprognostic (1.30e-1)" "unprognostic (1.72e-1)" "unprognostic (5.14e-2)" "prognostic unfavorable (4.51e-7)" "unprognostic (2.10e-1)" "unprognostic (1.83e-1)" "unprognostic (1.87e-2)" "unprognostic (5.43e-2)" 23.2 12.9 15.6 14.9 18.6 30.2 22.2 28.6 20.1 22.6 15.2 17.8 15.7 20.2 14.8 15.5 17.9 13.1 20.1 19.7 19.6 13.4 16.2 18.5 17.8 13.4 13.2 23.1 18.9 21.4 17.1 18.4 11.9 17.1 18.1 19.4 16.9 14.6 42.1 22.9 17.6 17.7 12.5 17.2 17.5 16.4 16.2 22.2 19.2 29.2 17.3 18.3 19.1 20.6 24.8 20.5 22.1 23.0 23.3 28.5 31.7 18.4 27.1 24.2 26.8 19.0 28.9 37.8 19.1 25.8 20.7 23.1 31.1 30.2 40.8 28.5 17.5 41.7 26.3 16.3 20.1 38.7 27.4 21.3 29.3 36.2 44.6 25.7 26.7 29.6 25.7 26.6 29.2 14.1 39.3 22.0 34.4 19.8 18.3 36.4 57.9 25.9 20.5 35.4 30.6 28.8 33.1 37.8 33.1 31.4 19.0 56.9 25.0 25.1 33.5 25.7 30.8 26.2 34.8 30.2 22.7 31.6 20.7 5.1 4.9 5.5 7.2 4.3 8.9 6.4 8.9 7.9 4.0 9.2 9.3 10.7 9.3 9.9 8.9 8.3 6.2 4.2 15.6 18.6 28.6 20.1 19.7 19.6 13.4 13.2 11.9 12.5 16.2 20.6 47.5 12.8 21.3 75.4 29.5 35.4 10.9 16.7 40.5 21.4 22.9 18.3 39.9 10.0 18.5 16.5 18.8 13.9 28.8 33.2 17.6 10.7 23.7 30.6 32.0 26.7 27.0 27.3 110.8 14.7 30.8 22.6 31.6 38.1 12.7 19.3 16.4 17.0 11.7 21.9 112.6 26.5 8.2 18.6 15.3 18.4 22.4 18.7 10.6 87.1 16.0 15.0 27.8 102.5 126.6 15.9 18.9 19.9 29.2 21.4 22.6 14.8 15.1 31.3 6.6 38.3 22.0 32.1 22.5 28.2 33.4 27.9 27.7 12.6 18.9 20.8 FOXK2 "ILF, ILF1" ENSG00000141568 "Forkhead box K2" Q01167 17 82519713-82644662 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027523, HPA073491" Approved Supported Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 10: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Vesicles, Mitochondria" "HPA027523: AB_10601013, HPA073491: " "unprognostic (2.39e-1)" "unprognostic (8.28e-2)" "unprognostic (2.05e-1)" "unprognostic (9.52e-2)" "unprognostic (3.11e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.24e-6)" "unprognostic (3.35e-2)" "unprognostic (2.25e-1)" "unprognostic (5.19e-2)" "unprognostic (2.18e-2)" "unprognostic (2.26e-1)" "unprognostic (3.80e-3)" "unprognostic (2.24e-2)" "unprognostic (4.89e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-2)" 14.0 24.0 10.7 12.6 13.2 8.0 12.1 14.7 16.3 14.2 1.2 18.1 9.3 19.7 9.8 20.2 13.2 10.0 17.1 12.4 10.5 12.7 13.1 14.2 12.5 5.8 7.1 14.7 15.4 20.0 17.7 15.7 6.3 13.3 9.4 11.6 12.1 12.5 43.0 18.8 12.1 16.4 3.0 11.6 14.7 28.1 9.4 18.4 15.4 28.4 11.9 15.5 13.4 12.7 48.4 50.4 46.3 50.9 26.2 28.5 31.0 27.6 31.6 47.4 47.9 49.1 30.1 40.7 19.6 34.4 52.3 27.6 49.7 32.0 44.4 28.3 47.9 42.3 32.7 49.4 41.0 47.3 27.2 27.2 57.2 50.4 56.8 29.2 48.9 43.7 57.7 40.7 26.3 28.8 81.8 30.4 26.5 39.7 38.2 53.0 39.4 34.2 21.7 40.1 76.2 56.1 27.4 69.0 65.1 48.8 48.7 54.3 38.3 62.2 43.2 42.2 56.6 46.7 45.1 53.5 33.4 39.0 33.4 1.5 1.0 1.2 1.4 0.7 1.1 1.5 1.1 1.4 1.2 1.0 0.8 0.9 0.1 1.6 0.9 2.0 1.3 0.6 10.7 13.2 14.7 16.3 12.4 10.5 5.8 7.1 6.3 3.0 9.4 12.7 21.5 51.3 27.1 23.5 11.5 37.2 8.0 10.6 10.2 19.2 17.7 15.7 19.5 7.2 16.2 14.7 12.5 11.9 19.3 15.6 3.9 8.7 15.6 19.4 22.4 14.9 10.9 7.8 44.6 10.7 8.8 13.2 14.3 26.7 2.5 22.1 10.8 13.4 20.0 47.1 39.6 12.6 8.2 17.3 22.0 24.1 9.3 19.2 12.4 20.6 13.9 12.3 6.2 33.2 49.1 11.4 12.4 13.2 13.3 13.6 12.2 7.1 13.9 16.7 0.0 19.8 16.6 15.0 10.3 17.0 43.0 9.7 11.6 30.6 13.0 10.7 FOXN2 HTLF ENSG00000170802 "Forkhead box N2" P32314 2 48314637-48379295 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 54.0;brain: 53.3" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 152.3;Oligodendrocytes: 282.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003485 Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm Vesicles "HPA003485: AB_1078905" "unprognostic (5.38e-2)" "unprognostic (1.48e-1)" "unprognostic (1.86e-2)" "unprognostic (2.65e-3)" "prognostic favorable (3.85e-4)" "unprognostic (4.00e-1)" "unprognostic (2.32e-2)" "unprognostic (1.52e-1)" "unprognostic (8.95e-2)" "unprognostic (2.59e-1)" "unprognostic (5.15e-3)" "unprognostic (4.14e-2)" "prognostic unfavorable (2.81e-5)" "unprognostic (2.24e-2)" "unprognostic (1.55e-1)" "unprognostic (2.34e-2)" "unprognostic (1.12e-2)" 17.9 5.5 13.3 15.4 30.3 54.0 8.0 25.3 19.0 7.7 4.2 7.7 8.3 6.7 4.2 9.3 5.5 9.7 8.6 13.9 16.3 6.6 19.8 9.5 19.4 24.1 21.0 5.9 8.9 9.5 3.0 13.4 21.9 5.0 8.0 3.4 5.5 4.2 4.8 3.6 10.3 9.8 20.0 18.1 7.9 6.3 19.2 14.9 6.9 6.4 17.1 10.6 3.9 53.3 13.1 19.5 22.2 19.6 17.2 12.7 24.3 14.4 15.8 11.9 13.2 17.3 15.9 28.4 18.7 17.0 14.5 16.2 13.7 16.5 17.2 22.3 11.7 56.1 13.3 17.4 30.0 30.9 42.1 11.4 6.9 12.9 22.3 9.6 12.8 11.6 26.6 32.7 19.5 10.1 34.4 20.3 16.8 9.8 10.2 17.0 46.5 23.2 10.2 16.5 12.4 12.6 6.9 13.2 24.9 7.5 5.7 18.0 15.0 16.0 16.1 15.2 15.2 17.8 14.2 40.5 13.9 27.5 22.2 120.9 32.4 129.6 24.0 26.2 27.4 21.2 23.1 22.4 33.6 20.6 17.2 17.7 40.8 25.7 36.4 20.8 28.8 17.2 13.3 30.3 25.3 19.0 13.9 16.3 24.1 21.0 21.9 20.0 19.2 53.3 22.1 0.0 7.4 66.6 31.3 15.6 27.5 10.0 15.4 6.7 5.4 5.6 11.1 14.3 6.1 1.8 0.0 6.7 28.3 7.0 5.9 6.0 4.8 8.9 17.2 21.8 2.4 22.5 28.1 5.4 32.1 13.3 14.3 13.3 22.8 1.2 20.7 19.7 17.9 13.5 25.2 8.0 8.2 39.5 47.3 4.7 12.2 44.4 12.4 35.6 44.1 7.8 26.8 152.3 282.0 11.0 7.1 11.3 31.0 35.2 11.3 4.8 3.3 3.6 6.6 17.8 27.4 22.7 13.1 11.9 21.2 16.6 38.3 2.8 8.9 35.9 FPGT GFPP ENSG00000254685 "Fucose-1-phosphate guanylyltransferase" O14772 1 74198212-74234086 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072331 Uncertain Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA072331: " "unprognostic (1.53e-1)" "unprognostic (1.94e-1)" "unprognostic (8.18e-3)" "unprognostic (4.32e-2)" "unprognostic (5.14e-2)" "unprognostic (2.46e-1)" "prognostic unfavorable (2.30e-4)" "unprognostic (1.86e-1)" "unprognostic (5.14e-2)" "unprognostic (2.58e-1)" "unprognostic (7.59e-2)" "unprognostic (1.33e-1)" "unprognostic (3.59e-3)" "unprognostic (1.44e-1)" "unprognostic (7.88e-2)" "unprognostic (3.53e-2)" "unprognostic (1.91e-1)" 10.5 10.5 3.7 9.9 5.6 4.2 12.9 5.4 4.9 8.9 6.2 12.0 11.7 8.7 10.6 10.7 9.2 13.2 8.7 4.0 5.0 15.4 14.1 8.9 9.0 5.8 5.4 13.3 10.4 13.5 5.3 10.8 6.2 9.9 11.1 6.8 10.6 8.5 4.9 12.0 12.3 8.8 5.3 10.1 12.6 8.1 5.0 8.5 19.5 5.6 9.8 8.3 6.0 8.3 12.4 10.1 7.5 11.0 17.0 15.8 11.2 16.0 10.6 10.8 12.7 5.7 9.1 7.6 19.2 9.5 12.2 10.3 13.6 14.6 17.1 15.4 5.8 17.3 11.1 9.7 14.1 13.2 12.7 13.1 18.6 10.8 5.1 7.4 11.3 10.5 18.2 8.8 17.1 3.3 7.4 2.7 8.2 15.9 9.1 7.8 17.5 10.8 9.5 8.9 7.8 7.8 11.8 17.1 18.6 2.4 20.6 14.9 10.3 4.7 8.8 25.8 12.2 9.6 7.3 10.2 19.0 12.8 16.2 19.5 20.1 21.7 5.5 20.5 6.5 5.0 5.5 5.2 12.6 6.1 6.2 5.6 6.1 5.8 18.4 1.2 7.6 10.7 3.7 5.6 5.4 4.9 4.0 5.0 5.8 5.4 6.2 5.3 5.0 8.3 7.1 6.4 3.2 0.0 3.0 6.8 4.9 13.3 4.6 7.1 7.6 5.6 10.2 14.3 9.3 11.0 2.1 12.7 2.5 7.8 19.6 5.3 8.9 6.0 4.8 4.9 6.0 9.5 0.0 7.1 11.0 7.0 4.1 4.2 5.1 4.9 6.4 9.8 15.1 3.3 0.0 7.3 6.1 9.4 4.6 7.3 10.2 10.3 5.4 0.0 9.0 10.6 8.2 0.0 0.0 6.5 8.9 5.7 1.2 2.5 11.0 15.3 12.7 5.5 26.3 5.8 7.2 9.7 10.4 5.7 6.5 6.2 5.2 4.9 7.3 3.0 FPGT-TNNI3K ENSG00000259030 "FPGT-TNNI3K readthrough" 1 74198235-74544393 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 8.7" "Cell type enhanced" "Detected in many" "Astrocytes: 13.1;Cardiomyocytes: 10.2;Cone photoreceptor cells: 10.4;Excitatory neurons: 10.3;Inhibitory neurons: 11.2;Oligodendrocyte precursor cells: 17.1;Oligodendrocytes: 26.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC TERT1: 2.3;CAPAN-2: 2.2;SiHa: 3.1" HPA072331 Approved Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA072331: " "unprognostic (6.29e-2)" "unprognostic (4.96e-2)" "unprognostic (1.99e-1)" "unprognostic (1.46e-1)" "unprognostic (1.24e-1)" "unprognostic (3.44e-3)" "unprognostic (8.37e-2)" "unprognostic (1.70e-2)" "unprognostic (6.63e-2)" "unprognostic (6.85e-2)" "unprognostic (1.04e-1)" "unprognostic (8.37e-2)" "unprognostic (6.76e-3)" "unprognostic (3.20e-2)" "unprognostic (2.75e-1)" "unprognostic (1.11e-2)" "unprognostic (7.87e-3)" 2.4 1.2 0.8 0.5 1.3 0.4 1.4 2.9 1.9 1.1 0.0 1.8 0.3 1.4 0.8 1.4 1.3 0.8 8.7 1.0 1.2 1.6 0.4 1.4 0.6 1.0 1.0 1.3 0.5 1.0 1.4 0.5 1.4 1.2 0.7 3.4 0.9 1.3 3.5 2.1 0.8 1.5 1.1 1.5 1.0 0.8 0.9 0.2 1.1 1.8 0.6 1.3 1.1 2.4 0.0 0.5 0.3 0.7 0.4 2.3 0.0 1.0 0.5 0.1 0.1 0.5 2.2 0.0 1.5 0.1 0.0 0.0 0.1 1.5 0.2 0.0 0.0 0.8 0.0 0.0 0.3 0.2 0.1 0.9 0.9 0.0 0.1 0.3 0.1 0.1 0.0 0.8 0.5 0.0 0.0 0.1 0.0 0.8 0.4 1.1 1.8 0.0 0.2 0.0 0.5 1.5 3.1 0.1 0.1 0.0 0.0 1.0 0.1 0.3 0.1 0.1 0.4 0.1 0.0 0.9 0.4 0.5 0.4 1.3 1.6 1.4 0.4 1.9 1.2 0.9 1.4 0.8 0.9 0.9 1.8 0.9 1.8 0.4 0.5 0.8 1.6 1.6 0.8 1.3 2.9 1.9 1.0 1.2 1.0 1.0 1.4 1.1 0.9 2.4 0.5 3.2 1.1 13.1 0.9 0.1 0.5 0.2 0.0 4.9 0.6 0.9 10.2 1.5 0.7 0.0 10.4 0.2 0.2 0.5 0.0 0.2 1.4 0.6 0.3 0.9 3.0 0.0 10.3 1.0 0.2 1.3 0.0 0.2 2.5 1.6 1.8 0.5 0.2 5.0 11.2 0.2 0.0 0.9 0.3 0.6 2.8 0.7 1.8 7.5 0.1 1.1 0.0 17.1 26.7 1.3 1.6 0.7 0.3 0.3 0.0 1.4 1.6 2.7 0.0 1.5 1.1 2.1 1.7 0.1 0.1 0.0 0.4 0.8 0.5 0.2 FRAT1 ENSG00000165879 "FRAT regulator of WNT signaling pathway 1" Q92837 10 97319271-97321915 "Predicted intracellular proteins" "Wnt signaling pathway" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 25.2;Early spermatids: 31.3;Kupffer cells: 26.1;Late spermatids: 85.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 8.7;neutrophil: 10.1" "Lineage enriched" "Detected in many" 5 "granulocytes: 10.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB046472, HPA055258" Approved Approved Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 6: T47d - Mammary gland" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Cytosol" "CAB046472: AB_1849131, HPA055258: AB_2682763" "unprognostic (1.48e-2)" "prognostic favorable (5.92e-4)" "unprognostic (3.54e-1)" "unprognostic (1.13e-2)" "unprognostic (1.45e-1)" "prognostic favorable (2.75e-4)" "unprognostic (1.11e-2)" "unprognostic (4.44e-3)" "unprognostic (5.73e-2)" "unprognostic (2.50e-2)" "unprognostic (6.36e-3)" "unprognostic (1.89e-1)" "prognostic favorable (6.36e-5)" "unprognostic (6.38e-2)" "unprognostic (5.27e-2)" "unprognostic (4.31e-2)" "unprognostic (1.43e-2)" 3.2 2.9 2.6 5.0 2.6 10.6 2.4 3.8 3.5 2.5 1.8 3.2 4.4 2.6 1.0 2.4 3.0 1.2 3.1 2.8 3.1 2.1 11.8 3.3 3.8 3.6 3.4 2.4 3.9 2.0 2.1 1.2 3.1 4.0 1.9 1.9 3.7 1.6 3.8 4.2 4.5 1.5 2.9 12.6 4.8 10.9 3.9 4.1 2.0 2.6 2.4 2.3 2.1 2.6 0.7 1.3 1.4 6.7 1.8 0.9 1.5 0.8 2.9 0.5 0.6 0.2 0.8 4.5 1.5 0.5 1.0 2.0 1.1 1.4 0.1 4.0 2.0 3.8 0.8 1.8 0.6 1.4 4.0 0.8 2.0 0.2 0.9 2.7 1.2 6.1 1.6 3.1 0.4 4.2 4.0 7.9 1.9 4.8 5.5 3.3 0.3 2.9 0.5 1.0 0.7 2.2 1.0 2.1 1.5 1.4 7.7 5.4 1.1 0.3 0.4 1.0 0.3 2.9 1.7 1.5 0.5 7.0 0.0 0.9 2.0 8.7 0.5 1.3 0.4 0.5 0.4 0.7 1.0 0.5 0.7 0.5 10.1 0.2 1.5 0.6 0.3 0.5 2.6 2.6 3.8 3.5 2.8 3.1 3.6 3.4 3.1 2.9 3.9 2.6 4.1 3.2 5.8 1.0 5.8 1.1 1.1 0.9 1.2 25.2 2.9 1.9 3.3 5.7 0.9 1.8 0.0 0.6 16.8 6.0 0.0 1.4 31.3 5.8 1.6 4.0 4.2 4.2 0.7 2.0 1.7 1.5 2.0 4.1 0.0 5.0 3.3 15.6 3.9 3.3 1.6 4.9 4.1 26.1 1.8 85.2 1.2 15.5 3.6 0.0 12.5 4.9 13.4 0.5 0.7 1.1 2.3 1.9 1.1 2.5 3.8 1.0 3.3 8.4 0.0 3.4 1.7 1.2 0.6 1.6 1.6 2.3 9.0 4.7 2.8 2.2 FSD1L "CCDC10, CSDUFD1, FSD1CL, FSD1NL" ENSG00000106701 "Fibronectin type III and SPRY domain containing 1 like" Q9BXM9 9 105447796-105552433 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 43.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 423.3;Early spermatids: 97.2;Excitatory neurons: 79.0;Rod photoreceptor cells: 121.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035138 Approved Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 77: Retina - Visual perception" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA035138: AB_10601324" "unprognostic (9.28e-2)" "unprognostic (4.04e-3)" "unprognostic (1.73e-1)" "unprognostic (1.88e-3)" "unprognostic (3.93e-2)" "unprognostic (1.82e-2)" "unprognostic (3.17e-5)" "unprognostic (4.20e-2)" "unprognostic (5.65e-2)" "unprognostic (9.64e-3)" "unprognostic (2.66e-3)" "unprognostic (3.32e-2)" "unprognostic (8.28e-2)" "unprognostic (2.92e-1)" "unprognostic (1.87e-1)" "unprognostic (8.07e-2)" "unprognostic (1.22e-3)" 1.2 3.5 8.4 2.1 9.4 2.4 1.6 7.8 10.0 1.7 6.3 2.6 4.5 2.1 3.3 0.9 7.1 1.4 4.1 8.9 12.3 2.1 0.7 2.2 1.4 13.2 11.4 1.4 1.4 2.0 3.3 0.9 11.5 1.6 2.4 43.2 1.1 1.6 7.3 1.1 3.7 1.5 11.7 1.4 2.2 5.8 12.5 1.6 2.0 13.3 1.5 1.1 0.9 12.0 3.3 3.8 5.6 3.9 1.6 3.2 2.0 3.1 1.8 2.5 2.5 1.7 1.4 8.3 1.2 2.7 3.0 1.3 3.6 1.6 3.5 11.1 1.3 1.4 5.3 2.3 2.5 4.9 3.4 1.5 1.6 3.6 5.5 3.2 2.4 3.9 1.8 5.1 2.5 1.1 8.4 3.1 3.5 0.4 2.2 10.6 3.8 0.7 2.6 0.7 12.3 5.9 3.5 0.9 3.0 2.3 3.7 1.7 3.2 4.4 2.7 3.7 4.2 2.6 9.9 2.2 3.1 3.0 1.6 0.4 0.9 0.0 0.5 0.6 0.2 1.8 0.7 0.5 0.6 0.6 0.0 0.3 0.2 0.5 0.4 0.6 0.2 0.2 8.4 9.4 7.8 10.0 8.9 12.3 13.2 11.4 11.5 11.7 12.5 12.0 2.9 3.2 1.1 23.8 4.2 1.0 2.0 2.5 0.0 23.1 2.3 2.0 6.0 1.5 3.5 7.3 423.3 0.3 3.4 3.0 1.9 22.7 97.2 47.5 5.7 3.3 10.7 1.7 79.0 3.8 1.3 5.2 2.6 15.1 14.0 10.4 1.1 1.3 3.8 52.2 59.2 6.3 2.0 1.2 3.5 68.2 5.0 5.3 10.6 16.9 21.0 12.7 1.0 21.6 66.9 5.2 7.1 6.8 3.0 1.1 7.8 2.4 44.9 121.1 13.1 6.3 4.1 26.0 26.1 0.3 0.9 0.0 2.8 2.2 6.8 0.2 FST FS ENSG00000134363 Follistatin P19883 5 53480626-53487134 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 68.7" "Cell type enriched" "Detected in many" 6 "Granulosa cells: 700.1" "Cancer enhanced" "Detected in all" "liver cancer: 45.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 351.1;HaCaT: 292.3;HBEC3-KT: 191.3;HMC-1: 206.5;PC-3: 558.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA016612, CAB026025" Approved Approved Vesicles "Secreted to blood" NA NA 1800000 "Cluster 32: T-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Vesicles "CAB026025: , HPA016612: " "unprognostic (1.43e-1)" "unprognostic (6.50e-2)" "unprognostic (1.44e-1)" "unprognostic (7.73e-3)" "unprognostic (2.30e-1)" "unprognostic (1.50e-3)" "unprognostic (8.02e-2)" "unprognostic (2.32e-2)" "unprognostic (3.06e-1)" "unprognostic (1.57e-1)" "unprognostic (1.93e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (4.44e-5)" "unprognostic (1.21e-3)" "unprognostic (2.48e-1)" "unprognostic (2.07e-2)" "unprognostic (2.18e-1)" 26.1 6.2 0.8 3.0 0.5 0.4 15.2 0.4 0.7 7.7 0.7 9.8 1.8 4.2 3.7 6.5 11.8 7.2 9.4 2.0 2.0 2.9 68.7 8.2 1.6 1.8 1.0 9.9 2.6 0.5 5.9 24.1 0.9 15.5 3.0 0.3 11.3 10.8 9.2 18.0 8.8 4.7 0.5 0.3 11.1 5.0 1.1 2.3 4.0 7.7 12.9 40.4 7.5 0.7 20.0 1.8 33.7 0.0 38.6 13.5 55.4 76.3 351.1 46.4 45.4 0.3 0.2 0.0 0.6 19.9 2.3 292.3 0.0 191.3 32.7 0.8 0.2 4.0 1.7 31.3 20.4 0.3 206.5 31.0 0.5 84.5 55.0 31.3 40.0 0.0 0.0 0.6 29.7 0.1 0.1 1.6 52.1 0.0 558.2 4.2 43.6 0.0 0.0 31.9 0.5 0.1 3.1 0.2 2.0 83.9 0.3 0.3 0.2 124.1 35.3 13.2 11.1 0.4 0.1 0.1 14.8 4.1 116.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.5 0.4 0.7 2.0 2.0 1.8 1.0 0.9 0.5 1.1 0.7 5.2 0.0 1.1 0.0 1.0 20.0 31.5 64.4 13.1 0.0 0.9 23.4 11.4 0.0 8.3 0.0 0.0 0.6 0.0 0.0 0.0 1.6 0.4 0.1 3.4 2.9 0.0 0.0 0.1 4.6 14.8 107.7 3.6 0.1 0.0 700.1 1.1 57.2 1.8 0.0 0.7 0.0 2.0 0.8 16.4 1.5 3.1 1.5 5.4 0.0 0.0 0.0 0.0 0.0 0.0 16.6 0.0 11.3 0.2 37.1 0.0 0.1 1.6 0.0 13.1 29.6 33.3 0.3 12.2 4.0 4.7 6.0 2.0 0.3 0.0 51.8 FSTL1 "FRP, FSL1, OCC-1, OCC1, tsc36" ENSG00000163430 "Follistatin like 1" Q12841 3 120392293-120450993 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 352.1;Fibroblasts: 521.9;Leydig cells: 327.4;Peritubular cells: 270.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "basophil: 12.0" "Lineage enriched" "Detected in single" 14 "granulocytes: 12.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 1782.4;BJ: 2156.3;fHDF/TERT166: 2692.9;HBF TERT88: 1741.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035251, HPA040815" Uncertain Approved Vesicles,Cytosol "Secreted to blood" NA NA 34000000 "Cluster 34: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Cytosol" "HPA035251: AB_10601906, HPA040815: AB_2732489" "unprognostic (2.60e-1)" "unprognostic (1.59e-3)" "unprognostic (8.84e-2)" "unprognostic (4.54e-3)" "unprognostic (4.10e-2)" "unprognostic (1.35e-1)" "unprognostic (9.88e-2)" "unprognostic (3.05e-2)" "unprognostic (1.19e-2)" "unprognostic (3.88e-2)" "unprognostic (3.54e-2)" "unprognostic (2.64e-2)" "prognostic unfavorable (1.33e-4)" "unprognostic (4.89e-3)" "unprognostic (1.72e-2)" "unprognostic (1.05e-2)" "unprognostic (4.47e-3)" 432.4 134.3 20.5 116.3 18.1 2.2 166.1 22.8 22.7 279.9 83.0 156.4 37.1 157.5 50.8 126.1 150.6 257.0 242.7 20.6 22.8 45.4 35.7 120.7 50.3 28.5 44.6 90.3 37.3 35.5 25.7 442.0 23.1 188.3 90.4 29.8 59.3 184.4 31.8 64.2 69.1 409.6 22.7 63.1 68.6 33.5 22.7 24.2 78.8 89.8 38.8 260.4 104.3 20.6 81.0 21.2 222.9 91.8 1304.4 1782.4 1.3 2156.3 1208.9 1374.5 1211.0 0.1 178.5 0.8 178.8 2692.9 112.8 20.5 68.6 270.0 1741.5 1.1 32.5 0.4 159.8 0.3 286.0 1.2 0.9 1362.7 8.5 884.5 192.7 612.1 811.6 11.2 0.5 0.3 227.6 0.5 22.6 2.0 181.3 0.4 181.9 0.7 92.7 1.0 150.4 1.7 39.2 93.5 764.6 13.6 76.5 462.6 23.5 6.2 986.8 507.4 479.8 268.0 323.8 1.0 1.1 2.3 177.4 0.9 67.0 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 2.6 20.5 18.1 22.8 22.7 20.6 22.8 28.5 44.6 23.1 22.7 22.7 20.6 76.9 64.1 9.4 56.5 1.1 64.1 31.9 36.4 10.2 2.3 25.6 24.6 127.5 8.6 42.5 23.9 0.0 114.4 2.5 0.9 0.0 62.6 2.3 44.4 176.7 111.4 3.0 3.6 9.6 5.8 352.1 521.9 3.1 23.0 1.3 66.5 142.5 17.4 20.6 1.7 16.2 0.2 8.2 10.8 91.6 9.8 327.4 11.5 110.3 30.0 9.9 116.1 0.0 9.5 0.9 117.8 0.7 270.8 0.9 108.4 0.0 5.5 74.9 4.3 59.2 62.5 129.3 1.5 4.4 2.2 48.2 54.7 7.1 47.5 0.9 65.3 FTCDNL1 FONG ENSG00000226124 "Formiminotransferase cyclodeaminase N-terminal like" E5RQL4 2 199760544-199851192 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 39.8;Excitatory neurons: 43.5;Oligodendrocytes: 115.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA065748 Approved Vesicles "Secreted in other tissues" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA065748: " "unprognostic (1.78e-1)" "unprognostic (1.70e-1)" "unprognostic (1.27e-2)" "unprognostic (9.80e-2)" "unprognostic (3.09e-1)" "unprognostic (7.21e-2)" "unprognostic (1.54e-3)" "unprognostic (1.59e-1)" "unprognostic (1.03e-1)" "unprognostic (4.82e-2)" "unprognostic (5.37e-2)" "unprognostic (9.86e-2)" "prognostic favorable (3.31e-4)" "unprognostic (3.92e-2)" "unprognostic (4.63e-2)" "prognostic unfavorable (5.74e-4)" "unprognostic (1.21e-2)" 2.4 4.9 4.4 0.9 7.9 2.3 2.1 5.4 5.5 0.6 1.8 1.1 1.0 0.4 1.8 1.3 1.9 0.9 2.9 4.5 4.8 4.2 10.0 1.4 2.0 6.1 6.7 1.0 2.2 1.5 0.9 0.6 5.7 1.2 1.1 1.4 2.4 0.6 8.1 1.2 0.8 1.1 6.1 4.6 0.9 1.0 6.0 0.7 5.7 8.4 0.8 0.7 0.9 7.6 0.6 1.9 0.1 0.0 1.9 1.1 1.4 0.7 0.7 1.0 0.4 0.0 3.5 2.0 0.2 0.8 5.7 0.0 0.9 5.3 1.2 2.3 0.5 1.5 0.8 1.7 0.7 5.5 6.5 0.8 0.2 0.4 0.1 0.7 0.0 4.9 2.7 0.1 0.7 6.0 1.9 2.1 1.6 0.5 4.0 0.3 0.2 0.0 0.4 0.0 2.3 0.0 3.4 3.2 3.2 1.3 4.8 7.1 0.6 2.7 0.0 1.8 1.1 4.7 2.9 1.1 5.2 2.7 1.3 0.0 4.1 1.7 0.4 5.5 1.7 3.4 1.7 0.6 5.8 2.1 1.1 1.8 0.0 1.1 5.1 8.7 0.0 1.4 4.4 7.9 5.4 5.5 4.5 4.8 6.1 6.7 5.7 6.1 6.0 7.6 0.8 0.0 0.0 39.8 3.2 2.7 2.9 0.0 13.6 3.3 6.2 5.5 5.7 4.3 1.3 3.7 4.2 1.5 3.3 0.3 1.9 0.2 2.4 8.4 0.8 1.5 0.0 5.9 43.5 0.7 1.4 1.4 4.6 3.3 0.0 5.9 2.2 6.9 7.4 1.7 23.5 1.2 0.0 8.1 4.7 1.0 0.3 8.2 7.2 17.8 2.1 1.7 0.0 24.6 115.4 0.3 0.1 0.4 1.4 2.6 1.0 10.6 0.0 6.5 0.0 2.4 3.4 0.4 2.0 6.9 2.3 0.3 1.5 10.3 1.1 1.2 FTO "ALKBH9, KIAA1752, MGC5149" ENSG00000140718 "FTO alpha-ketoglutarate dependent dioxygenase" Q9C0B1 16 53701692-54158512 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase, Transferase" "Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 173.3;Excitatory neurons: 226.1;Inhibitory neurons: 240.7;Oligodendrocyte precursor cells: 210.6;Oligodendrocytes: 282.5;Respiratory ciliated cells: 182.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017123, HPA041086, HPA068695" Enhanced Supported Vesicles,Cytosol No No 540000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol Vesicles "CAB017123: , HPA041086: AB_2677293, HPA068695: AB_2732117" "unprognostic (9.74e-2)" "unprognostic (2.49e-1)" "unprognostic (9.30e-2)" "unprognostic (1.24e-2)" "unprognostic (1.81e-1)" "unprognostic (2.09e-2)" "unprognostic (2.95e-2)" "unprognostic (1.41e-1)" "unprognostic (8.67e-2)" "unprognostic (1.02e-1)" "unprognostic (3.88e-2)" "unprognostic (6.80e-2)" "unprognostic (1.44e-1)" "unprognostic (5.81e-3)" "unprognostic (1.78e-1)" "unprognostic (4.30e-3)" "unprognostic (6.11e-3)" 24.4 33.6 31.8 12.5 36.6 8.2 36.3 30.1 37.7 25.8 31.0 22.2 7.7 26.9 21.4 17.2 25.3 21.6 27.1 35.2 39.5 25.0 17.4 36.8 15.0 29.2 31.3 27.2 20.7 40.6 26.2 20.1 31.9 20.0 14.1 38.4 18.9 23.9 33.1 21.4 12.5 29.9 30.5 16.4 15.0 8.3 33.8 17.0 27.5 23.0 14.8 21.9 18.5 43.9 15.1 26.8 35.0 35.9 67.3 50.4 11.5 35.6 32.2 29.3 8.5 16.8 19.3 34.4 38.2 46.3 16.6 21.7 32.4 34.9 42.5 16.0 25.5 15.5 33.6 31.7 46.2 12.5 17.1 55.9 36.5 26.6 32.5 36.6 44.1 25.1 15.2 8.4 48.1 11.8 28.0 19.2 18.1 15.5 17.5 42.2 52.9 32.3 44.6 12.3 43.0 29.7 40.4 23.6 10.8 33.7 31.1 29.3 42.4 36.4 23.9 19.8 22.1 15.9 13.9 35.0 33.9 22.9 28.7 14.9 17.9 9.7 25.6 22.7 32.4 17.6 24.4 25.9 23.8 17.4 22.5 24.4 2.9 26.4 16.5 9.5 26.6 23.1 31.8 36.6 30.1 37.7 35.2 39.5 29.2 31.3 31.9 30.5 33.8 43.9 15.1 80.1 62.0 173.3 10.3 12.4 10.0 8.6 13.6 22.8 69.1 39.5 22.3 15.7 54.4 7.3 12.5 9.3 10.2 4.8 7.9 9.0 39.1 11.0 18.3 17.4 6.6 9.7 226.1 5.7 7.4 23.1 9.7 9.9 25.9 16.8 11.0 13.8 9.2 16.8 240.7 6.6 10.2 9.0 13.2 69.9 14.3 11.8 10.6 134.0 5.5 19.6 10.3 210.6 282.5 5.5 5.0 15.1 18.7 6.0 4.5 15.8 182.7 14.1 13.1 21.6 16.8 3.5 3.4 11.0 9.1 5.1 12.9 17.8 6.3 7.9 FUCA1 ENSG00000179163 "Alpha-L-fucosidase 1" P04066 1 23845077-23868290 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 181.7;Distal enterocytes: 226.6;Paneth cells: 221.0;Proximal enterocytes: 210.9;Syncytiotrophoblasts: 200.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 165.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046542, HPA056371" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 60000000 "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA046542: AB_2679691, HPA056371: AB_2683108" "unprognostic (6.94e-3)" "unprognostic (6.53e-2)" "unprognostic (2.68e-3)" "prognostic favorable (2.45e-4)" "unprognostic (5.64e-3)" "unprognostic (2.59e-3)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (4.99e-1)" "unprognostic (2.18e-2)" "unprognostic (2.05e-1)" "unprognostic (4.23e-2)" "prognostic favorable (5.70e-13)" "unprognostic (3.75e-2)" "unprognostic (4.35e-2)" "unprognostic (1.54e-2)" "unprognostic (2.13e-3)" 34.2 34.4 8.3 49.8 8.2 7.7 26.3 8.3 11.2 54.5 23.8 124.2 90.3 20.7 113.0 17.0 51.1 46.6 20.6 8.3 10.5 78.2 104.8 55.1 168.2 9.5 8.8 23.8 23.9 56.9 17.6 72.6 9.6 50.2 140.7 5.7 40.8 60.4 15.8 14.9 81.3 26.7 9.3 71.8 63.9 27.7 10.8 26.8 70.6 17.7 94.1 74.9 13.2 12.8 15.9 10.6 2.2 31.9 4.2 0.3 11.0 16.6 34.4 17.1 31.6 14.5 165.1 23.9 40.9 21.3 18.8 9.4 15.3 35.4 22.4 16.9 25.6 19.7 9.2 32.7 14.2 2.0 62.7 15.3 19.7 6.2 8.1 55.2 6.9 13.3 9.3 0.5 20.6 17.5 5.0 17.7 5.4 48.1 16.9 26.9 0.2 26.2 63.5 40.5 10.9 10.6 47.9 18.5 26.2 17.9 13.6 7.8 1.8 5.8 9.0 38.9 5.6 28.5 31.0 8.5 14.5 58.9 9.5 54.8 100.4 51.9 27.2 99.9 23.1 23.8 19.5 22.9 44.0 14.1 18.9 22.0 12.8 44.6 91.1 25.4 21.4 64.8 8.3 8.2 8.3 11.2 8.3 10.5 9.5 8.8 9.6 9.3 10.8 12.8 12.9 25.6 28.6 4.2 10.5 3.6 27.4 99.3 6.8 4.4 22.2 10.4 5.6 40.0 77.8 84.6 0.0 181.7 13.9 226.6 15.6 64.1 61.0 31.5 2.8 11.6 10.8 20.6 5.8 50.3 24.2 16.7 33.1 13.3 8.2 11.1 25.7 42.7 156.4 0.0 6.3 44.4 44.7 121.0 13.5 24.4 23.3 85.4 8.8 2.8 29.6 13.0 10.3 4.0 4.7 34.9 221.0 19.5 8.7 23.6 210.9 40.2 53.7 5.0 6.6 16.7 13.2 109.0 24.8 8.5 2.8 200.6 11.2 34.6 79.5 40.3 FUT4 "CD15, ELFT, FCT3A, FUC-TIV" ENSG00000196371 "Fucosyltransferase 4" P22083 11 94543840-94549898 "Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "bone marrow: 100.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 22.8;Ductal cells: 19.3;Gastric mucus-secreting cells: 21.9;Intestinal goblet cells: 23.7;Pancreatic endocrine cells: 22.5" "Cancer enhanced" "Detected in all" "colorectal cancer: 11.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HL-60: 37.4;NB-4: 24.2;THP-1: 46.6;U-937: 32.9" "Low region specificity" "Detected in single" "CAB000014, CAB016129" Enhanced Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 27: Mucus-secreting cells - Mucin production" Vesicles "CAB000014: , CAB016129: AB_626918" "unprognostic (6.36e-2)" "unprognostic (7.53e-2)" "unprognostic (4.70e-3)" "unprognostic (2.46e-3)" "unprognostic (1.46e-2)" "unprognostic (2.29e-2)" "unprognostic (1.66e-2)" "prognostic unfavorable (3.64e-4)" "unprognostic (7.26e-2)" "unprognostic (4.14e-1)" "unprognostic (4.81e-3)" "unprognostic (1.27e-1)" "unprognostic (9.08e-3)" "unprognostic (8.17e-2)" "unprognostic (1.37e-1)" "unprognostic (4.04e-1)" "unprognostic (3.10e-3)" 3.7 1.2 1.3 4.7 1.1 100.8 2.5 1.2 1.4 2.3 0.2 9.2 12.3 2.8 1.2 1.8 2.1 3.7 1.7 1.6 1.1 1.9 1.5 2.1 3.7 1.3 1.0 2.9 6.7 0.5 1.3 3.1 1.3 1.6 8.7 1.6 6.8 2.2 0.9 0.8 10.8 2.5 1.6 3.6 10.8 1.3 1.4 3.7 1.2 1.1 2.8 2.1 1.3 1.9 2.9 1.4 1.7 0.0 5.3 4.8 8.9 2.6 1.3 2.3 2.5 12.5 4.0 0.0 6.1 4.4 1.2 1.4 2.9 0.3 2.1 19.1 2.9 9.4 2.2 0.3 2.7 37.4 8.0 4.1 0.1 2.9 0.0 0.5 3.6 8.3 9.7 0.0 2.7 1.4 7.9 24.2 3.4 11.6 3.4 6.9 0.0 0.0 2.4 1.9 2.4 0.9 1.5 3.7 1.5 5.1 2.1 46.6 3.3 1.8 4.9 0.0 1.0 1.1 0.6 0.0 1.6 32.9 1.1 0.5 0.8 0.7 0.2 0.4 0.1 0.1 0.2 0.3 0.4 0.1 0.2 0.1 0.3 0.2 1.2 0.5 0.5 0.2 1.3 1.1 1.2 1.4 1.6 1.1 1.3 1.0 1.3 1.6 1.4 1.9 2.9 0.0 0.0 1.3 1.8 1.7 3.0 0.9 1.2 1.0 1.8 1.8 0.9 22.8 1.9 1.8 4.2 15.6 2.6 12.1 0.0 19.3 0.3 1.1 2.8 2.3 10.2 3.4 1.5 17.9 3.2 6.0 21.9 3.3 0.0 2.6 3.9 1.0 9.0 0.0 1.9 23.7 0.0 12.9 3.5 0.8 4.4 5.2 3.6 3.7 13.6 0.4 0.0 3.0 3.4 22.5 5.8 1.2 0.5 2.9 11.6 2.4 1.7 7.9 0.0 3.1 2.6 1.7 3.5 2.1 0.6 2.2 3.1 2.0 17.9 1.4 FXYD6-FXYD2 ENSG00000255245 "FXYD6-FXYD2 readthrough" 11 117820163-117876667 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "kidney: 7.5;salivary gland: 4.5" "Cell type enriched" "Detected in some" 6 "Distal tubular cells: 97.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "MOLT-4: 6.5;RPTEC TERT1: 7.3" "HPA068838, HPA075209" Approved Approved "Nuclear membrane,Vesicles" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear membrane, Vesicles" "HPA068838: AB_2686047, HPA075209: AB_2732285" 0.3 0.2 0.4 0.0 0.4 0.0 0.2 0.5 0.5 0.4 0.2 0.9 0.1 1.0 0.8 0.1 0.6 0.9 0.6 0.4 0.4 7.5 0.2 0.4 0.0 0.3 0.3 1.3 1.9 0.0 0.3 0.2 0.3 0.3 0.0 0.0 4.5 0.1 0.2 0.1 0.3 0.3 0.3 0.9 0.3 0.3 0.3 0.4 0.3 0.2 0.1 0.4 0.2 0.4 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.5 0.0 0.4 0.0 0.0 0.0 0.2 0.0 7.3 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.5 0.5 0.4 0.4 0.3 0.3 0.3 0.3 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.6 0.0 11.0 0.0 0.0 0.0 0.0 97.8 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.3 2.5 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 15.8 0.0 0.0 6.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 FYCO1 "FLJ13335, ZFYVE7" ENSG00000163820 "FYVE and coiled-coil domain autophagy adaptor 1" Q9BQS8 3 45917899-45995824 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 263.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 89.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035526, HPA057966" Uncertain Enhanced Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 15: RT4 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" Vesicles "HPA035526: AB_10672867, HPA057966: AB_2683567" "unprognostic (2.45e-1)" "unprognostic (6.62e-2)" "unprognostic (6.97e-3)" "unprognostic (1.14e-3)" "unprognostic (7.65e-2)" "unprognostic (1.23e-2)" "unprognostic (1.57e-2)" "unprognostic (4.53e-3)" "unprognostic (5.85e-2)" "unprognostic (8.85e-2)" "unprognostic (2.36e-1)" "unprognostic (2.98e-1)" "prognostic favorable (3.33e-11)" "unprognostic (2.90e-1)" "unprognostic (1.42e-1)" "unprognostic (2.89e-2)" "unprognostic (6.99e-2)" 16.7 13.0 10.5 9.7 12.0 6.5 13.4 9.6 9.4 23.1 11.3 42.0 8.0 25.6 10.3 21.3 15.4 18.7 66.8 8.6 10.3 10.7 10.8 14.7 8.6 15.5 10.8 23.1 12.7 20.3 7.6 8.2 14.8 19.3 10.7 33.0 14.9 22.9 263.3 19.3 14.4 28.2 15.1 10.2 20.4 3.3 11.9 10.5 16.5 104.6 8.2 39.6 16.9 15.1 10.8 10.3 3.0 13.0 27.9 21.8 4.9 10.2 23.7 13.1 14.6 5.6 9.3 7.9 5.6 14.2 12.7 7.9 8.5 17.0 15.7 3.3 9.0 11.4 8.7 6.3 19.0 8.8 7.9 24.3 16.7 21.1 20.5 20.3 26.7 13.4 7.4 11.3 9.5 6.7 9.0 5.5 4.5 8.8 9.8 3.1 8.3 4.4 15.9 37.2 2.2 3.4 6.4 20.0 17.6 4.4 9.7 5.7 20.8 5.0 5.9 17.0 5.7 6.4 4.4 2.7 17.2 11.1 9.6 0.7 0.5 0.3 2.0 0.5 2.7 0.2 1.2 2.1 0.2 0.2 0.5 0.7 0.4 1.5 0.3 1.3 1.2 0.7 10.5 12.0 9.6 9.4 8.6 10.3 15.5 10.8 14.8 15.1 11.9 15.1 9.5 28.9 13.7 12.4 4.8 4.1 4.8 5.6 3.4 11.2 8.5 4.8 89.3 8.6 13.0 16.5 35.5 4.3 8.7 6.8 3.9 8.8 0.1 6.4 8.9 9.3 9.6 6.9 0.8 8.3 2.2 14.0 12.8 11.2 2.5 14.9 11.4 9.2 4.1 0.0 0.8 7.6 2.0 5.8 4.6 1.6 12.8 5.1 10.6 10.3 4.0 20.0 6.2 8.0 21.2 11.0 2.5 17.7 3.0 17.3 8.7 6.2 18.6 37.1 6.6 20.8 12.8 2.3 0.8 8.4 4.1 2.9 12.7 6.1 6.2 7.9 FZD3 ENSG00000104290 "Frizzled class receptor 3" Q9NPG1 8 28494205-28574267 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Neurogenesis, Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 14.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 98.0;Excitatory neurons: 155.9;Inhibitory neurons: 82.3;Rod photoreceptor cells: 87.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 9.3" "Group enriched" "Detected in many" 5 "dendritic cells: 9.3;T-cells: 2.3" "Cell line enhanced" "Detected in many" "AF22: 53.2;Karpas-707: 27.9;SCLC-21H: 39.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024995, HPA042320" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles Nucleoplasm "CAB024995: , HPA042320: AB_2677948" "unprognostic (1.21e-1)" "unprognostic (1.73e-1)" "prognostic favorable (1.17e-4)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (2.57e-4)" "unprognostic (1.69e-2)" "unprognostic (4.26e-4)" "unprognostic (2.11e-1)" "prognostic favorable (3.71e-4)" "unprognostic (2.86e-2)" "unprognostic (1.68e-2)" "unprognostic (1.09e-2)" "unprognostic (1.38e-1)" "unprognostic (4.44e-2)" "unprognostic (3.77e-2)" "unprognostic (6.09e-3)" 1.0 2.9 5.2 1.5 6.7 1.5 2.3 5.7 9.9 2.4 13.8 2.2 1.3 3.4 6.9 1.9 3.5 1.3 1.1 6.8 4.0 2.6 0.6 1.0 2.1 1.8 5.4 7.0 3.5 4.2 3.8 1.3 4.2 4.3 1.2 14.7 3.3 5.5 1.2 1.5 1.0 2.4 0.9 0.6 2.5 5.0 3.2 1.8 3.4 1.3 1.4 1.9 1.6 2.6 14.8 3.1 53.2 10.2 0.0 0.8 7.9 0.5 1.1 3.0 1.3 3.1 3.1 6.9 2.6 0.3 6.6 5.2 8.0 8.8 2.1 9.1 5.8 4.8 1.0 2.0 0.0 2.7 7.9 0.6 4.1 0.2 2.3 0.6 0.6 7.3 3.5 27.9 0.1 3.7 0.2 5.8 13.3 6.4 4.6 3.3 8.0 6.8 4.0 4.4 39.6 10.7 2.9 7.5 8.7 7.0 7.4 4.0 0.0 0.0 14.3 2.0 3.7 5.1 6.1 6.7 4.2 0.0 2.7 0.7 0.2 0.0 1.6 0.2 2.1 1.1 1.2 2.3 0.9 0.6 1.6 1.6 0.1 0.9 0.0 9.3 0.0 0.7 5.2 6.7 5.7 9.9 6.8 4.0 1.8 5.4 4.2 0.9 3.2 2.6 1.7 9.6 12.0 65.6 5.6 6.6 7.9 17.0 10.8 28.1 21.6 11.7 6.0 4.3 17.7 9.2 98.0 10.5 15.7 1.4 1.9 12.1 25.7 24.2 18.7 4.3 28.7 5.0 155.9 14.9 9.7 8.8 8.2 27.7 5.7 29.3 8.6 3.0 4.2 21.9 82.3 6.3 8.2 1.0 7.4 11.9 48.1 2.1 33.8 14.0 0.7 17.0 2.1 52.8 14.3 11.8 3.4 51.1 17.2 14.1 0.8 11.4 17.5 87.1 26.3 8.6 15.0 58.4 45.6 5.6 4.7 4.8 5.0 15.0 5.4 7.7 FZD7 FzE3 ENSG00000155760 "Frizzled class receptor 7" O75084 2 202033855-202038441 "G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 30.9;Breast myoepithelial cells: 37.0;Cardiomyocytes: 21.1;Fibroblasts: 23.5;Proximal enterocytes: 21.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 30.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 42.8;BJ hTERT+: 48.4;CAPAN-2: 62.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059979, HPA069165, HPA076183" Approved Supported Vesicles NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 35: Glandular cells - Unknown function" Vesicles "HPA059979: , HPA069165: AB_2686096, HPA076183: " "unprognostic (3.44e-2)" "unprognostic (6.89e-2)" "unprognostic (9.30e-3)" "unprognostic (2.44e-3)" "unprognostic (4.92e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.71e-5)" "unprognostic (1.40e-1)" "unprognostic (4.92e-2)" "unprognostic (8.22e-2)" "unprognostic (2.73e-2)" "unprognostic (1.10e-1)" "unprognostic (1.87e-3)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (4.16e-2)" "unprognostic (2.05e-3)" 10.2 3.0 4.9 5.6 4.7 0.4 15.5 30.2 4.3 13.2 6.3 36.7 6.9 18.4 14.1 9.4 16.8 6.3 14.4 8.8 5.0 8.2 1.2 5.3 3.9 5.2 4.9 25.0 1.7 1.1 9.3 5.7 5.5 19.2 5.5 1.3 21.7 23.5 26.7 10.9 10.8 11.1 4.9 1.9 5.9 2.1 4.5 1.1 5.1 9.5 3.8 27.1 15.3 5.6 10.3 5.2 33.2 10.8 10.6 7.9 14.8 42.8 48.4 11.9 13.9 32.2 62.7 0.1 25.1 26.2 7.9 10.6 6.0 1.3 13.7 5.4 8.6 1.1 2.1 2.7 7.2 2.1 2.1 7.6 1.0 6.4 3.7 9.5 0.0 0.7 2.9 2.6 9.8 4.2 0.0 5.7 36.6 2.0 3.5 4.2 6.4 1.1 1.9 6.1 5.5 12.6 5.4 0.4 6.8 26.7 3.8 2.5 0.1 23.8 8.8 15.0 5.4 2.7 2.2 0.1 4.9 0.5 16.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 4.7 30.2 4.3 8.8 5.0 5.2 4.9 5.5 4.9 4.5 5.6 3.5 0.0 8.1 3.6 2.0 10.3 8.3 1.9 14.8 0.0 30.9 37.0 21.1 1.5 0.3 1.8 0.0 0.5 2.0 4.7 1.9 1.6 0.1 1.5 2.0 1.7 1.2 0.0 1.5 0.2 1.1 23.5 2.6 3.6 1.3 7.5 0.7 0.7 1.5 0.0 0.2 9.9 0.0 0.8 5.7 0.5 5.3 2.0 3.6 0.0 0.1 7.5 0.0 0.0 0.1 0.6 2.1 4.9 1.7 6.9 21.3 0.1 0.9 0.6 6.6 13.5 16.3 1.6 2.9 11.4 9.8 0.8 2.5 0.5 7.6 1.8 G2E3 "FLJ20333, KIAA1333, PHF7B" ENSG00000092140 "G2/M-phase specific E3 ubiquitin protein ligase" Q7L622 14 30559158-30620064 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 42.3" "Group enriched" "Detected in all" 6 "Early spermatids: 722.5;Late spermatids: 233.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001601 Uncertain Approved "Golgi apparatus,Vesicles,Cytosol" NA Yes "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "Golgi apparatus, Vesicles" "HPA001601: AB_1079198" "unprognostic (4.75e-2)" "unprognostic (6.31e-2)" "unprognostic (2.27e-2)" "unprognostic (4.86e-2)" "unprognostic (9.10e-2)" "unprognostic (3.99e-2)" "unprognostic (5.44e-6)" "unprognostic (1.17e-2)" "unprognostic (2.81e-2)" "unprognostic (1.86e-1)" "unprognostic (3.13e-2)" "unprognostic (1.35e-1)" "unprognostic (1.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.23e-1)" "unprognostic (2.32e-2)" "unprognostic (2.12e-2)" 4.8 3.2 2.1 6.4 7.0 10.0 6.4 11.6 5.5 6.4 0.7 5.6 5.0 6.3 3.7 6.2 4.8 3.8 4.8 2.4 5.6 4.5 5.2 4.5 9.1 3.1 2.5 6.1 5.2 5.6 2.7 6.3 2.7 5.1 5.3 13.8 4.9 4.6 3.0 5.9 4.9 6.2 1.0 6.3 5.3 42.3 7.0 14.3 6.6 3.9 8.9 4.9 3.9 9.6 37.9 15.6 33.7 16.1 11.2 15.0 30.5 31.9 12.9 20.2 22.9 17.1 20.5 32.9 10.9 18.4 15.9 29.7 36.4 18.8 42.2 25.7 15.7 19.6 17.1 31.0 10.3 34.0 22.5 8.1 7.4 15.1 34.9 18.3 22.9 22.5 21.2 24.2 29.0 21.9 22.6 9.6 31.2 27.5 32.7 21.4 0.0 8.2 10.5 22.3 28.4 19.9 27.7 16.0 7.9 20.5 19.1 12.5 17.3 19.7 21.9 16.9 21.9 14.1 47.7 38.8 5.4 16.6 29.2 20.2 6.5 12.9 7.6 8.5 10.1 9.2 7.4 6.3 5.6 9.9 9.2 7.8 5.9 6.5 11.3 6.8 6.6 4.1 2.1 7.0 11.6 5.5 2.4 5.6 3.1 2.5 2.7 1.0 7.0 9.6 22.6 19.2 9.0 17.9 32.9 21.9 22.5 11.8 26.7 34.9 13.0 10.8 10.0 12.8 13.6 5.5 25.0 17.8 23.0 9.0 9.8 8.9 722.5 13.9 26.6 17.0 13.8 42.7 45.3 7.1 22.7 20.6 14.3 14.1 17.1 23.3 13.2 7.5 14.2 35.3 38.4 14.7 14.2 13.9 12.4 233.9 16.4 16.5 8.8 24.4 16.2 15.5 32.0 41.7 43.1 10.7 9.4 14.3 14.4 22.5 5.6 12.0 10.9 33.4 52.6 18.0 18.6 69.8 42.7 20.7 25.4 10.0 24.9 11.9 12.4 20.6 GAA ENSG00000171298 "Glucosidase alpha, acid" P10253 17 80101556-80119881 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, FDA approved drug targets, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 156.2;Extravillous trophoblasts: 143.9;Kupffer cells: 122.7;Syncytiotrophoblasts: 166.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 66.6;eosinophil: 22.8;intermediate monocyte: 50.3;myeloid DC: 39.7;neutrophil: 27.0;non-classical monocyte: 68.5" "Group enriched" "Detected in all" 10 "dendritic cells: 39.7;granulocytes: 27.0;monocytes: 68.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026970, HPA029126" Enhanced Approved Vesicles NA NA 3800000 "Cluster 14: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA026970: AB_2672065, HPA029126: AB_2672918" "unprognostic (1.13e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (7.66e-4)" "unprognostic (2.94e-2)" "unprognostic (1.14e-2)" "unprognostic (7.96e-2)" "unprognostic (2.05e-2)" "unprognostic (1.19e-1)" "unprognostic (2.90e-1)" "unprognostic (1.43e-1)" "unprognostic (1.29e-2)" "unprognostic (2.76e-1)" "unprognostic (1.46e-1)" "unprognostic (7.02e-2)" "unprognostic (2.38e-1)" "unprognostic (1.78e-2)" "unprognostic (1.18e-1)" 31.7 29.9 16.9 22.6 20.8 16.7 30.1 19.2 26.5 25.8 17.1 29.2 24.7 31.2 35.2 15.8 29.1 29.9 35.1 18.3 24.7 37.6 47.3 44.4 22.5 28.2 21.6 18.8 37.2 33.3 38.8 48.5 26.6 33.2 8.7 6.6 37.7 23.6 47.0 25.5 26.9 14.6 21.0 54.3 26.9 56.0 26.0 20.4 32.6 25.1 7.0 31.5 22.0 31.4 35.6 67.8 13.2 43.2 40.4 40.2 85.1 21.8 39.6 16.2 13.2 20.3 56.3 12.7 56.5 17.3 13.8 14.8 4.1 25.2 3.8 16.5 49.9 0.2 12.8 73.3 69.7 1.7 40.4 86.7 35.4 30.6 10.5 32.8 28.9 33.5 12.9 51.5 12.4 81.3 6.0 8.4 27.3 8.7 46.8 30.9 44.8 22.2 13.1 36.5 15.1 43.4 28.5 31.3 39.0 8.1 89.5 50.1 18.8 59.7 31.5 43.6 8.1 121.4 36.5 3.8 19.1 32.8 38.4 0.6 66.6 22.8 3.7 50.3 4.4 3.1 2.8 3.8 39.7 3.0 3.2 2.3 27.0 3.0 68.5 9.5 2.1 32.9 16.9 20.8 19.2 26.5 18.3 24.7 28.2 21.6 26.6 21.0 26.0 31.4 21.9 19.2 41.3 31.6 9.3 11.2 19.6 38.7 8.0 16.1 24.1 28.2 19.9 24.3 24.7 14.7 8.4 156.2 11.8 11.5 5.9 25.2 55.7 14.3 16.7 21.6 6.1 4.8 16.2 15.8 143.9 33.0 20.4 27.8 8.8 28.5 23.6 26.4 99.8 11.8 18.9 10.9 12.2 122.7 29.6 29.3 23.9 83.9 24.9 20.6 39.1 32.1 8.2 11.6 12.5 9.4 13.5 19.2 12.9 20.2 31.4 21.5 9.3 18.5 6.6 15.0 13.9 66.0 29.4 10.3 8.4 166.2 8.2 30.2 14.4 14.8 GABARAP "ATG8A, MM46" ENSG00000170296 "GABA type A receptor-associated protein" O95166 17 7240008-7242449 "Predicted intracellular proteins, Transporters" "Apoptosis, Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 498.6;Ductal cells: 462.5;Plasma cells: 482.6;Squamous epithelial cells: 457.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065883 Approved Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 59: Non-specific - Transcription" Vesicles "HPA065883: AB_2685574" "unprognostic (2.58e-1)" "unprognostic (4.55e-3)" "unprognostic (1.92e-1)" "unprognostic (9.08e-2)" "unprognostic (1.19e-1)" "unprognostic (4.30e-2)" "unprognostic (1.36e-1)" "unprognostic (2.57e-1)" "unprognostic (1.01e-1)" "unprognostic (1.58e-1)" "prognostic favorable (9.52e-5)" "unprognostic (1.85e-1)" "unprognostic (1.45e-2)" "unprognostic (2.09e-1)" "unprognostic (2.85e-2)" "unprognostic (1.22e-2)" "unprognostic (1.58e-1)" 609.8 848.2 777.0 344.7 799.2 478.8 610.9 826.8 1091.7 696.5 776.2 600.1 292.4 548.9 574.9 479.4 561.2 302.8 740.4 753.9 807.5 741.1 625.2 569.8 308.5 819.2 790.0 751.1 732.2 662.1 851.7 302.2 829.3 604.6 372.4 280.6 592.3 385.4 1001.1 662.8 496.8 341.4 817.6 651.6 658.9 604.5 803.0 389.2 552.3 916.4 411.0 534.0 547.5 862.7 233.5 342.1 598.0 404.5 887.1 999.5 227.0 377.1 645.5 330.1 491.2 141.9 200.6 233.9 233.2 672.0 430.6 206.9 428.1 329.7 441.7 421.8 474.4 182.8 301.3 377.3 858.3 118.7 369.6 1016.1 445.4 424.5 378.9 925.6 623.7 350.0 143.6 256.8 577.5 159.4 288.4 267.6 242.0 420.9 329.1 393.8 273.3 318.8 682.9 240.9 262.8 695.8 284.1 262.5 409.4 439.3 333.4 228.4 563.7 363.6 211.1 357.7 314.8 280.6 294.2 152.6 586.1 296.2 383.5 2968.2 4092.7 3746.6 766.9 3665.8 796.1 1262.2 906.3 810.4 3152.3 1156.6 812.9 765.5 7095.7 734.6 3213.5 2410.2 1132.5 4745.4 777.0 799.2 826.8 1091.7 753.9 807.5 819.2 790.0 829.3 817.6 803.0 862.7 24.0 89.8 120.1 44.4 183.6 20.8 3.9 21.3 498.6 2.4 64.1 31.9 0.5 54.3 81.3 27.6 0.0 24.3 35.8 302.0 43.0 462.5 24.1 25.5 32.4 61.5 396.5 179.3 36.7 309.6 31.1 124.2 264.6 24.8 150.0 6.9 45.0 39.9 78.2 1.7 37.7 314.3 34.6 147.0 60.8 71.3 21.1 397.4 33.8 43.1 399.2 15.1 32.0 21.1 87.8 375.2 374.3 13.9 482.6 6.0 384.7 72.0 166.4 3.0 6.6 5.2 74.2 22.1 5.8 457.2 23.2 52.9 105.2 5.2 237.1 4.9 GABARAPL1 "APG8L, ATG8B, ATG8L, gec1" ENSG00000139112 "GABA type A receptor associated protein like 1" Q9H0R8 12 10212458-10223128 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 432.4;Syncytiotrophoblasts: 929.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 62.1" "Group enriched" "Detected in many" 5 "granulocytes: 62.1;NK-cells: 22.6;T-cells: 26.7" "Cell line enhanced" "Detected in many" "HHSteC: 255.7;SiHa: 231.5;SuSa: 557.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051386, HPA065883" Approved Approved Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA051386: AB_2681463, HPA065883: AB_2685574" "unprognostic (9.58e-3)" "unprognostic (1.16e-1)" "unprognostic (4.23e-2)" "unprognostic (1.06e-1)" "unprognostic (8.46e-2)" "unprognostic (1.85e-3)" "prognostic favorable (2.36e-4)" "unprognostic (2.90e-1)" "unprognostic (6.38e-2)" "unprognostic (2.79e-2)" "unprognostic (9.25e-3)" "unprognostic (1.72e-1)" "prognostic favorable (8.19e-8)" "unprognostic (5.42e-2)" "unprognostic (2.57e-2)" "unprognostic (1.10e-1)" "unprognostic (1.77e-1)" 185.4 97.7 115.0 33.6 131.3 164.3 150.7 102.6 215.8 75.2 105.2 101.9 40.8 77.7 125.3 44.1 91.1 75.5 334.3 141.9 155.8 314.9 207.4 146.0 15.2 145.7 105.6 157.9 138.2 126.0 218.2 190.1 135.9 92.9 35.0 327.0 118.1 69.8 381.8 71.5 67.1 64.7 90.9 42.3 133.6 37.4 123.2 21.8 93.4 163.3 14.2 107.5 82.8 138.4 8.7 18.3 36.2 34.2 200.8 57.3 30.2 200.0 91.8 33.6 43.9 79.5 30.1 2.0 16.4 215.4 84.8 54.6 32.0 24.2 24.5 6.1 29.9 11.8 115.4 22.0 255.7 14.8 13.3 101.0 52.0 25.9 20.4 96.7 82.5 23.7 14.9 0.5 14.4 0.7 12.4 15.2 88.3 1.9 18.2 0.9 66.1 0.9 139.7 21.6 3.5 7.6 231.5 36.8 71.5 557.0 16.9 8.8 113.1 10.9 36.6 17.4 9.6 35.3 60.4 55.8 36.5 6.7 16.2 53.6 4.8 43.0 26.7 2.7 8.9 0.2 3.6 16.3 2.9 0.1 3.4 14.2 62.1 22.6 6.7 1.1 5.8 6.5 115.0 131.3 102.6 215.8 141.9 155.8 145.7 105.6 135.9 90.9 123.2 138.4 216.8 60.9 35.7 15.0 23.5 62.8 196.6 57.1 101.3 118.3 45.0 26.0 197.8 72.9 33.6 58.8 154.3 310.8 171.8 38.5 432.4 62.5 295.1 57.8 75.0 88.0 71.0 61.7 45.5 57.2 31.1 128.9 61.7 143.9 17.7 15.4 63.9 112.1 72.0 89.2 41.4 37.6 75.3 73.1 56.4 70.3 25.7 111.6 74.7 18.7 24.6 114.2 25.7 13.0 26.6 45.4 31.5 24.5 57.2 130.7 55.0 250.3 16.1 237.6 19.7 96.8 85.2 10.0 8.8 32.6 42.3 929.0 125.6 25.8 11.5 169.0 GABRD ENSG00000187730 "Gamma-aminobutyric acid type A receptor subunit delta" O14764 1 2019329-2030758 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 49.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 14.7;Excitatory neurons: 30.0;Horizontal cells: 13.5;Inhibitory neurons: 37.4;Spermatogonia: 11.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 1.4;HMC-1: 1.2;MCF7: 4.4;NB-4: 2.7;SH-SY5Y: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044371 Enhanced Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 6: Brain - Smell perception" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus, Vesicles" "HPA044371: AB_2678916" "unprognostic (4.28e-2)" "unprognostic (1.90e-1)" "unprognostic (5.95e-8)" "unprognostic (6.34e-3)" "unprognostic (2.66e-3)" "unprognostic (1.04e-2)" "unprognostic (3.44e-3)" "unprognostic (2.14e-1)" "unprognostic (4.53e-2)" "unprognostic (1.12e-1)" "unprognostic (3.77e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (4.12e-8)" "unprognostic (1.72e-1)" "unprognostic (1.76e-1)" "unprognostic (2.77e-1)" "unprognostic (5.16e-2)" 0.3 1.5 12.8 0.0 16.9 0.0 0.5 49.6 40.5 0.1 0.1 0.2 0.0 0.3 0.1 0.3 0.2 0.4 0.7 14.7 5.4 0.7 0.2 0.9 0.2 14.3 18.1 0.2 0.1 0.7 2.7 0.1 20.2 0.2 0.0 1.4 0.3 0.0 0.3 0.4 0.2 0.3 1.0 0.3 0.1 3.6 29.7 0.1 0.9 0.4 0.0 0.2 0.2 14.7 0.0 0.3 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 2.7 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.8 16.9 49.6 40.5 14.7 5.4 14.3 18.1 20.2 1.0 29.7 14.7 1.0 3.2 3.6 4.9 0.1 0.5 0.0 0.0 0.0 14.7 0.3 0.0 0.9 0.0 6.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.2 3.4 0.0 0.0 30.0 0.0 0.3 0.5 0.0 0.2 2.5 0.3 0.0 0.0 0.1 13.5 37.4 0.0 0.0 0.0 0.3 0.2 0.0 0.9 0.0 8.4 0.0 1.4 0.0 3.0 4.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 4.4 1.6 0.0 0.0 4.8 0.1 11.3 0.1 0.0 0.3 0.4 0.2 0.1 0.1 GAD1 GAD ENSG00000128683 "Glutamate decarboxylase 1" Q99259 2 170813213-170861151 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Neurotransmitter biosynthesis" "Decarboxylase, Lyase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "brain: 98.5;parathyroid gland: 46.3;retina: 29.7" "Group enriched" "Detected in many" 8 "Inhibitory neurons: 392.8;Oligodendrocyte precursor cells: 146.8" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 20.1;HEL: 64.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 547.6" "CAB004415, HPA048871, HPA058412, CAB078176" Enhanced Supported Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane, Cytosol" "CAB004415: AB_627650, CAB078176: AB_2665792, HPA048871: , HPA058412: AB_2683710" "unprognostic (1.28e-1)" "prognostic favorable (7.31e-4)" "unprognostic (1.87e-2)" "prognostic favorable (8.61e-4)" "unprognostic (1.12e-1)" "unprognostic (3.05e-1)" "unprognostic (4.97e-7)" "unprognostic (1.51e-1)" "unprognostic (7.72e-2)" "unprognostic (4.27e-4)" "unprognostic (6.75e-2)" "unprognostic (9.18e-3)" "unprognostic (6.90e-5)" "unprognostic (2.93e-2)" "unprognostic (6.57e-2)" "unprognostic (1.56e-2)" "unprognostic (3.08e-3)" 0.2 3.0 22.1 0.0 29.9 3.3 0.1 15.5 33.0 1.0 0.0 0.0 0.0 1.6 4.3 0.4 0.2 0.1 0.0 17.1 98.5 4.8 0.1 0.2 0.1 12.4 41.6 0.2 0.2 46.3 5.0 0.4 17.6 0.8 0.1 29.7 0.1 0.3 0.0 0.2 0.1 0.0 12.7 0.1 0.0 3.2 31.1 0.8 0.1 0.0 0.2 0.6 0.4 14.2 18.2 0.7 0.0 7.3 0.0 0.0 0.1 0.4 0.0 2.6 1.7 4.6 6.7 0.0 0.9 0.5 2.9 20.1 2.3 0.6 1.6 2.8 13.4 64.5 6.0 0.2 0.0 0.3 1.1 0.0 5.5 0.0 2.3 0.6 0.1 0.5 17.0 0.3 0.8 1.5 0.0 0.0 8.1 9.7 6.7 1.0 4.6 0.4 8.5 9.4 6.7 2.1 12.6 0.0 3.5 0.6 0.2 0.0 0.0 12.0 1.7 2.4 7.0 0.0 0.0 0.1 11.5 3.2 16.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.1 29.9 15.5 33.0 17.1 98.5 12.4 41.6 17.6 12.7 31.1 14.2 0.0 0.0 0.0 14.7 0.0 0.3 2.1 7.7 2.2 32.5 0.1 0.1 1.3 0.0 3.6 0.0 10.4 0.0 0.0 0.2 7.9 4.5 5.6 4.4 0.4 0.4 3.0 5.5 2.6 5.6 0.1 0.2 0.0 2.9 0.0 5.5 0.0 0.0 4.0 5.0 392.8 0.3 2.0 0.8 0.4 6.2 0.6 0.5 0.0 7.5 0.0 4.9 0.0 146.8 7.6 2.9 0.0 0.0 0.1 0.9 0.0 0.0 4.7 6.0 0.0 0.0 1.2 4.4 7.7 0.6 0.1 0.5 0.0 0.1 0.1 0.4 GAK DNAJC26 ENSG00000178950 "Cyclin G associated kinase" O14976 4 849276-932373 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 134.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027405, HPA027459, HPA027463" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Vesicles "HPA027405: AB_10611111, HPA027459: AB_10599948, HPA027463: AB_10601959" "unprognostic (1.55e-1)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (3.24e-3)" "unprognostic (1.07e-1)" "unprognostic (3.50e-3)" "unprognostic (1.68e-1)" "unprognostic (7.07e-2)" "unprognostic (1.39e-2)" "unprognostic (3.34e-1)" "unprognostic (3.03e-2)" "unprognostic (3.33e-3)" "prognostic favorable (1.70e-6)" "unprognostic (1.09e-3)" "unprognostic (1.79e-1)" "unprognostic (6.26e-2)" "prognostic favorable (7.41e-4)" 31.9 40.7 21.1 25.9 22.5 35.5 34.0 20.1 29.7 42.7 20.1 56.3 51.2 41.9 8.0 49.7 43.0 17.7 25.4 21.5 17.8 55.0 47.7 46.0 25.6 28.7 19.8 40.5 53.1 22.7 37.1 15.6 22.1 41.8 14.8 9.4 71.0 13.3 31.4 40.4 57.4 9.8 17.7 61.5 54.2 45.8 20.6 21.6 38.5 6.6 12.9 38.7 39.3 20.5 36.0 28.3 16.9 29.0 16.6 14.2 43.6 33.0 19.7 22.3 18.5 35.9 49.8 30.4 20.9 20.1 40.3 29.7 17.7 27.4 10.5 30.7 27.9 35.3 29.5 27.5 31.1 36.2 53.0 20.5 23.2 22.7 11.0 14.2 24.7 35.3 38.4 37.4 15.2 34.7 61.6 92.1 30.4 38.2 46.3 50.2 19.4 27.4 18.2 28.8 29.0 31.3 19.3 24.2 23.3 14.1 39.2 30.7 40.8 30.9 18.0 31.8 45.1 59.5 41.3 33.8 34.9 43.7 29.0 3.0 10.3 12.8 8.8 9.8 7.6 4.9 5.8 6.1 6.5 3.9 3.3 4.8 7.4 4.8 24.6 7.6 5.6 9.4 21.1 22.5 20.1 29.7 21.5 17.8 28.7 19.8 22.1 17.7 20.6 20.5 24.7 25.6 33.2 34.0 33.9 17.0 15.3 17.9 14.8 27.2 25.3 17.7 12.2 18.6 28.2 25.8 64.6 19.0 46.2 131.3 9.8 18.8 99.1 32.2 21.6 26.7 29.4 26.1 25.7 28.0 17.5 19.5 93.8 52.5 18.3 31.2 18.5 31.6 36.6 11.8 23.5 66.5 26.4 35.9 18.4 134.7 25.1 35.5 16.0 59.0 28.8 16.3 35.0 9.0 24.4 37.6 71.1 18.8 26.1 28.4 65.8 31.0 33.8 26.9 19.7 17.9 18.0 32.9 27.4 19.9 22.3 31.1 34.6 41.6 65.0 44.6 GAL "GAL-GMAP, GALN, GLNN, GMAP" ENSG00000069482 "Galanin and GMAP prepropeptide" P22466 11 68683779-68691175 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Hormone, Neuropeptide" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 23 "brain: 645.9;pituitary gland: 885.8" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 22.2;Ductal cells: 38.9;Endometrial ciliated cells: 64.2;Endometrial stromal cells: 50.8;Exocrine glandular cells: 52.1;Extravillous trophoblasts: 48.7;Glandular and luminal cells: 26.4;Pancreatic endocrine cells: 39.5;Prostatic glandular cells: 82.5;Urothelial cells: 24.3" "Cancer enhanced" "Detected in many" "testis cancer: 22.2" "Region enriched" "Detected in many" 13 "hypothalamus: 645.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 267.2;HEK 293: 119.3;K-562: 139.5;NB-4: 493.5;SH-SY5Y: 189.6" "Region enhanced" "Detected in many" "hypothalamus: 82.6" "Low region specificity" "Detected in all" "HPA049864, CAB079779" Enhanced Supported Supported "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 60000 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 24: NB-4 - Immune response" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus" Vesicles "CAB079779: , HPA049864: AB_2680922" "unprognostic (8.56e-2)" "unprognostic (1.45e-2)" "unprognostic (7.50e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (2.70e-1)" "unprognostic (2.27e-2)" "unprognostic (8.07e-3)" "prognostic unfavorable (8.17e-4)" "unprognostic (5.98e-2)" "unprognostic (1.07e-2)" "unprognostic (8.84e-2)" "unprognostic (7.42e-2)" "unprognostic (1.20e-1)" "unprognostic (8.85e-2)" "unprognostic (7.88e-2)" "unprognostic (5.38e-2)" "unprognostic (3.24e-2)" 3.2 0.9 2.8 14.9 2.1 0.7 4.4 1.1 5.2 1.0 0.8 17.6 1.8 0.2 0.0 0.8 1.0 0.2 1.0 2.2 645.9 1.5 0.3 0.5 0.1 48.5 5.1 0.2 2.1 0.1 885.8 0.3 13.8 4.4 4.0 0.0 0.9 0.2 0.4 33.3 4.1 9.9 0.6 0.3 9.7 1.0 19.5 0.7 0.4 0.0 0.0 0.7 2.9 2.6 0.0 11.0 1.1 0.3 0.0 0.0 24.0 36.7 0.0 0.7 0.0 267.2 9.9 0.0 12.7 1.3 0.4 0.1 0.0 0.2 0.0 0.0 119.3 6.4 74.6 0.0 1.3 3.7 0.0 1.7 4.0 0.0 0.1 0.0 6.3 0.0 139.5 0.0 0.2 77.2 0.0 493.5 60.3 2.9 23.7 0.0 0.1 51.1 0.6 0.0 49.8 189.6 25.8 1.5 0.0 26.8 1.5 57.6 0.0 0.0 0.0 0.3 2.9 0.0 0.0 0.1 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 2.1 1.1 5.2 2.2 645.9 48.5 5.1 13.8 0.6 19.5 2.6 0.6 0.0 0.0 0.0 0.2 2.0 22.2 0.1 0.0 0.0 3.2 5.8 1.4 0.0 0.0 0.0 0.0 0.6 0.1 0.7 0.0 38.9 0.1 64.2 50.8 3.4 1.8 4.2 2.1 52.1 48.7 6.6 2.0 26.4 4.5 0.4 0.0 0.0 2.0 0.0 0.2 1.1 4.1 0.0 1.2 0.2 0.0 0.7 1.8 0.0 0.6 0.0 0.0 0.0 0.3 39.5 0.1 0.0 1.0 82.5 0.0 0.4 0.0 0.0 0.0 1.6 6.7 2.2 10.9 1.1 3.4 1.9 0.8 0.0 1.3 24.3 GAL3ST1 CST ENSG00000128242 "Galactose-3-O-sulfotransferase 1" Q99999 22 30554635-30574665 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 51.6;intestine: 24.4;kidney: 18.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 30.0;Muller glia cells: 35.3;Oligodendrocyte precursor cells: 26.7;Oligodendrocytes: 53.6;Proximal enterocytes: 48.1;Proximal tubular cells: 24.6" "Cancer enriched" "Detected in many" 6 "renal cancer: 38.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 27.6;CACO-2: 7.7;EFO-21: 14.6;K-562: 6.6;OE19: 10.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001220, HPA077138" Approved Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 45: Intestine - Brush border" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles Nucleoplasm "HPA001220: AB_1078933, HPA077138: " "unprognostic (2.69e-2)" "unprognostic (3.12e-4)" "unprognostic (5.93e-2)" "unprognostic (1.08e-2)" "unprognostic (2.32e-1)" "unprognostic (6.50e-3)" "unprognostic (1.53e-2)" "unprognostic (2.23e-1)" "unprognostic (2.89e-1)" "unprognostic (5.18e-2)" "unprognostic (1.19e-1)" "unprognostic (4.43e-2)" "prognostic unfavorable (1.79e-4)" "unprognostic (2.33e-1)" "unprognostic (4.23e-2)" "unprognostic (1.24e-1)" "unprognostic (3.56e-2)" 1.3 0.2 14.8 0.4 33.3 0.8 1.1 27.7 25.8 2.7 0.3 5.2 23.0 2.4 1.7 0.5 3.1 5.2 1.1 14.6 18.3 18.4 4.0 1.9 0.7 32.9 29.0 2.3 6.9 0.7 1.5 0.9 31.0 3.1 2.4 2.3 0.5 1.4 3.1 1.6 24.4 0.3 23.2 0.3 8.2 5.0 29.1 0.1 0.2 0.3 0.0 1.6 1.8 51.6 0.0 27.6 0.5 0.2 0.0 0.0 2.0 0.0 0.2 0.0 0.0 7.7 3.8 0.4 14.6 0.0 0.5 0.1 0.0 0.0 0.0 0.3 0.7 0.4 0.4 5.7 0.6 0.2 0.2 0.2 0.0 0.1 0.2 0.0 0.0 0.4 6.6 0.6 0.0 0.2 0.3 1.1 3.9 10.6 0.4 0.2 0.0 0.7 1.1 0.1 0.3 1.8 0.0 0.4 0.2 0.7 0.2 0.2 0.8 0.2 0.2 0.3 0.0 2.4 1.2 0.3 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.1 0.1 0.4 0.1 0.1 0.0 0.3 0.1 0.1 0.5 0.0 0.0 0.6 0.0 0.0 14.8 33.3 27.7 25.8 14.6 18.3 32.9 29.0 31.0 23.2 29.1 51.6 0.5 0.0 0.0 2.3 0.3 0.4 0.1 0.0 0.0 0.8 0.6 3.3 0.6 30.0 0.0 3.7 0.0 0.1 0.0 14.0 15.6 7.0 1.1 1.1 0.3 0.3 10.9 2.7 2.0 11.1 0.1 0.3 5.1 2.4 0.0 0.9 0.0 1.6 0.1 0.0 1.9 5.7 0.0 0.3 0.3 0.8 1.5 0.2 0.0 0.0 0.0 35.3 0.0 26.7 53.6 5.0 8.8 2.2 0.1 0.4 48.1 24.6 0.1 1.3 0.0 2.1 0.3 12.4 14.3 0.0 0.3 0.3 0.2 0.0 7.6 0.1 GALNT16 "GalNAc-T16, GALNTL1, KIAA1130" ENSG00000100626 "Polypeptide N-acetylgalactosaminyltransferase 16" Q8N428 14 69259277-69357033 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.8;heart muscle: 45.0" "Cell type enhanced" "Detected in many" "Astrocytes: 16.6;Cardiomyocytes: 46.7;Excitatory neurons: 27.6;Fibroblasts: 24.0;Inhibitory neurons: 23.8;Smooth muscle cells: 14.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.5;ASC diff: 11.7;hTEC/SVTERT24-B: 17.0;hTERT-RPE1: 17.2;SCLC-21H: 8.7;U-2 OS: 19.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059136, HPA075325" Approved Approved Vesicles,Cytosol NA NA 370000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Cytosol" "HPA059136: AB_2683919, HPA075325: " "unprognostic (9.71e-3)" "unprognostic (7.47e-2)" "unprognostic (4.02e-1)" "unprognostic (2.30e-2)" "unprognostic (6.71e-2)" "unprognostic (5.72e-3)" "unprognostic (3.18e-3)" "unprognostic (1.22e-1)" "unprognostic (1.02e-1)" "unprognostic (1.28e-2)" "unprognostic (3.62e-4)" "unprognostic (1.31e-2)" "prognostic favorable (5.23e-6)" "unprognostic (5.38e-3)" "unprognostic (3.34e-2)" "unprognostic (3.93e-2)" "unprognostic (7.96e-5)" 14.4 11.6 25.7 2.0 24.4 0.1 12.0 14.7 28.4 7.6 6.5 6.5 2.2 7.3 2.8 3.6 5.6 3.4 45.0 27.0 35.5 7.7 2.0 3.4 3.2 19.6 22.5 2.1 4.3 2.5 4.7 0.4 19.9 4.0 2.2 1.3 23.5 4.6 4.4 7.5 3.7 8.6 16.4 12.1 3.2 3.5 40.8 2.2 4.9 5.8 1.3 3.1 5.0 21.3 0.0 0.8 8.5 0.3 11.7 5.3 0.0 1.3 0.1 1.5 2.3 0.4 0.0 0.0 0.2 1.4 0.8 0.0 3.0 0.0 0.3 0.1 6.0 0.0 0.2 0.5 0.1 0.0 0.5 0.5 0.0 17.0 0.0 17.2 0.9 0.0 0.0 0.0 2.8 0.5 0.0 0.0 1.7 0.0 0.1 0.0 4.8 0.0 0.5 0.0 8.7 3.0 1.8 0.4 0.0 0.3 0.3 0.0 0.1 1.7 19.9 2.2 2.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.7 24.4 14.7 28.4 27.0 35.5 19.6 22.5 19.9 16.4 40.8 21.3 4.0 0.0 0.0 16.6 0.0 4.1 0.4 0.0 0.0 2.8 3.1 3.0 46.7 0.0 0.0 0.0 2.1 0.1 0.2 0.0 3.9 0.1 9.7 0.2 0.4 1.7 0.0 0.0 27.6 0.0 0.0 24.0 0.5 0.2 0.0 0.3 0.0 0.0 0.2 0.0 23.8 0.1 0.0 0.0 6.1 11.2 0.9 0.3 3.6 5.6 0.0 0.1 0.0 8.0 1.6 0.0 0.0 3.8 0.0 0.5 0.1 0.1 0.0 0.8 6.6 10.1 14.8 0.6 2.1 0.3 3.3 0.0 0.3 11.2 0.6 0.4 GALNT18 "GalNAc-T18, GALNT15, GALNTL4, MGC71806" ENSG00000110328 "Polypeptide N-acetylgalactosaminyltransferase 18" Q6P9A2 11 11270877-11622005 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 149.5;Excitatory neurons: 104.4;Inhibitory neurons: 156.3;Microglial cells: 79.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 42.1;HaCaT: 52.4;HBEC3-KT: 36.5;PC-3: 36.4;RPMI-8226: 39.3;SK-BR-3: 47.2;U-87 MG: 33.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012955, HPA070681" Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA 300000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "Vesicles, Cytosol" "HPA012955: AB_1849460, HPA070681: " "unprognostic (1.26e-1)" "unprognostic (2.80e-1)" "unprognostic (3.69e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (7.37e-2)" "unprognostic (1.22e-1)" "unprognostic (6.42e-3)" "unprognostic (6.68e-2)" "unprognostic (6.04e-2)" "unprognostic (2.05e-1)" "unprognostic (5.24e-2)" "unprognostic (1.70e-1)" "unprognostic (2.66e-3)" "unprognostic (3.54e-2)" "unprognostic (1.63e-1)" "unprognostic (2.10e-1)" "unprognostic (1.81e-2)" 18.0 4.7 19.1 4.1 17.7 0.0 15.6 17.1 20.8 13.0 10.7 24.8 3.0 24.0 2.4 7.7 12.0 11.2 26.9 29.5 12.9 26.5 10.5 51.2 5.4 12.2 17.2 4.9 8.2 9.8 6.4 24.4 13.9 13.0 3.2 3.6 17.0 9.3 10.7 13.0 8.8 13.3 12.3 3.6 6.8 14.7 19.7 6.3 42.8 6.2 3.3 11.7 11.5 12.9 42.1 15.0 2.0 9.1 0.0 0.0 0.3 4.5 11.2 0.6 0.0 1.7 5.4 0.1 3.1 0.1 5.6 52.4 9.9 36.5 0.1 0.0 14.6 0.0 0.1 0.1 0.5 0.0 0.0 0.2 14.9 0.0 13.5 0.0 0.0 18.5 0.0 0.1 1.9 10.2 0.5 0.1 1.5 0.1 36.4 0.0 0.0 39.3 27.5 5.1 0.6 4.1 7.6 47.2 0.3 1.4 9.9 0.1 0.0 0.7 8.1 0.4 0.2 0.0 0.0 0.0 33.6 0.0 10.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.1 17.7 17.1 20.8 29.5 12.9 12.2 17.2 13.9 12.3 19.7 12.9 40.5 44.8 6.9 149.5 0.1 5.6 6.6 18.3 12.0 1.6 1.6 2.5 8.5 30.0 13.7 20.2 2.1 49.2 0.4 0.8 15.6 19.9 2.2 1.9 0.4 40.6 0.0 0.0 104.4 4.0 3.5 5.4 0.0 1.3 1.3 16.7 18.5 2.6 2.6 0.0 156.3 0.4 8.2 0.8 1.1 1.4 1.5 0.4 1.8 79.6 0.0 43.1 0.0 8.5 10.5 7.3 0.2 3.0 0.2 13.4 0.0 40.8 14.3 2.1 13.1 15.1 7.4 0.6 1.1 1.8 5.4 15.5 0.3 46.7 1.1 1.9 GALNT5 GalNAc-T5 ENSG00000136542 "Polypeptide N-acetylgalactosaminyltransferase 5" Q7Z7M9 2 157257705-157318491 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.5;lung: 10.2;stomach 1: 12.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 157.0;Distal enterocytes: 48.3;Intestinal goblet cells: 75.5;Pancreatic endocrine cells: 53.5;Prostatic glandular cells: 40.1;Urothelial cells: 115.1" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 9 "cerebellum: 4.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 45.3;BJ: 29.8;BJ hTERT+: 53.5;fHDF/TERT166: 64.5;HaCaT: 51.8;K-562: 30.7;LHCN-M2: 52.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA008963, HPA009035" Approved Approved "Nucleoli,Golgi apparatus,Vesicles,Cytosol" NA NA 1300000 "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus, Cytosol" "Nucleoli, Vesicles" "HPA008963: AB_1078942, HPA009035: AB_1078943" "unprognostic (6.34e-3)" "unprognostic (9.31e-2)" "unprognostic (2.11e-2)" "unprognostic (9.89e-2)" "unprognostic (3.19e-2)" "unprognostic (2.46e-2)" "unprognostic (4.63e-3)" "unprognostic (1.88e-1)" "unprognostic (1.09e-1)" "unprognostic (6.93e-2)" "unprognostic (4.01e-3)" "unprognostic (1.78e-1)" "unprognostic (1.15e-2)" "unprognostic (6.27e-2)" "unprognostic (1.29e-1)" "unprognostic (1.88e-1)" "unprognostic (9.48e-3)" 0.1 0.0 0.0 0.7 0.0 0.6 1.1 4.0 0.3 1.1 5.2 10.6 2.2 0.1 0.1 4.5 0.0 2.7 0.4 0.4 0.0 0.0 0.0 10.2 0.0 0.1 0.1 0.1 0.0 0.1 0.6 0.0 0.2 0.7 13.5 0.1 8.2 0.1 0.0 0.3 4.1 0.4 0.0 0.1 12.8 0.1 0.1 0.1 0.1 0.1 1.7 4.5 4.6 0.2 45.3 4.8 0.0 0.0 2.0 17.0 0.0 29.8 53.5 0.5 1.1 1.9 24.4 0.0 0.1 64.5 0.0 51.8 0.9 10.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.0 0.2 0.0 0.9 0.0 0.0 0.0 30.7 0.0 52.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.1 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 25.4 0.3 0.6 0.1 0.0 0.1 0.0 4.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.3 0.4 0.0 0.1 0.1 0.2 0.0 0.1 0.2 0.1 157.0 36.1 0.0 0.1 0.8 13.3 20.2 6.2 0.0 0.5 2.8 0.5 2.8 32.9 0.0 0.0 0.0 0.2 48.3 0.0 1.2 6.9 1.2 0.0 0.6 2.4 5.2 0.8 3.2 0.0 2.1 35.7 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 75.5 6.1 0.0 0.7 0.5 0.0 0.3 3.6 0.0 1.6 0.0 0.0 0.0 0.1 53.5 26.4 0.0 1.4 40.1 3.1 0.2 10.0 0.0 0.0 0.5 1.2 2.6 0.5 4.5 0.1 0.0 0.3 0.0 22.7 115.1 GALNT8 GALNAC-T8 ENSG00000130035 "Polypeptide N-acetylgalactosaminyltransferase 8" Q9NY28 12 4720400-4851927 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 31.3;testis: 13.5" "Group enriched" "Detected in some" 6 "Early spermatids: 95.2;Intestinal goblet cells: 47.0;Late spermatids: 150.2" "Group enriched" "Detected in some" 4 "colorectal cancer: 1.2;glioma: 1.8;pancreatic cancer: 0.8;testis cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Karpas-707: 23.4;U-266/84: 7.6" "Not detected" "Not detected" "HPA012638, HPA073461" Supported Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA No "Cluster 22: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 2: Karpas-707 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA012638: AB_2294503, HPA073461: AB_2686604" "unprognostic (2.36e-2)" "unprognostic (1.95e-1)" "unprognostic (1.13e-2)" "unprognostic (1.75e-2)" "unprognostic (6.24e-2)" "unprognostic (2.87e-1)" "unprognostic (2.59e-2)" "unprognostic (3.79e-1)" "unprognostic (2.72e-1)" "unprognostic (5.76e-2)" "unprognostic (8.06e-5)" "unprognostic (1.16e-2)" "unprognostic (6.67e-5)" "unprognostic (5.18e-2)" "unprognostic (2.59e-2)" "unprognostic (2.53e-1)" "unprognostic (1.33e-2)" 0.4 0.6 3.2 1.8 3.3 0.0 0.6 2.7 5.1 0.5 2.0 14.0 5.7 0.3 0.1 0.1 0.6 0.0 2.5 3.2 2.8 0.4 0.2 0.3 0.2 3.4 3.2 0.7 0.2 0.0 2.8 0.1 3.3 0.4 31.3 0.2 0.4 0.3 0.1 0.2 12.6 0.8 2.9 0.5 0.5 13.5 3.3 0.0 0.2 0.0 0.0 0.4 0.3 4.1 0.0 0.0 0.5 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 23.4 0.0 0.0 0.0 0.1 3.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 3.2 3.3 2.7 5.1 3.2 2.8 3.4 3.2 3.3 2.9 3.3 4.1 0.1 6.4 0.5 1.3 0.5 0.0 0.0 0.1 0.6 2.1 0.1 2.3 4.5 0.0 0.0 0.0 0.0 0.0 1.5 1.8 0.0 0.0 95.2 0.5 0.1 0.5 6.6 0.0 1.1 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.7 47.0 0.0 0.0 0.0 150.2 1.5 0.1 0.0 3.7 0.2 0.5 0.0 15.1 7.4 0.2 0.6 2.6 0.0 0.1 1.0 1.0 0.0 0.6 6.6 0.7 0.1 12.3 8.3 0.0 0.0 0.0 0.8 0.3 2.2 0.0 GALNT9 GALNAC-T9 ENSG00000182870 "Polypeptide N-acetylgalactosaminyltransferase 9" Q9HCQ5 12 132196372-132329589 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.5;kidney: 9.4;thyroid gland: 13.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.7;Collecting duct cells: 27.6;Excitatory neurons: 37.1;Inhibitory neurons: 13.1;Proximal tubular cells: 8.2" "Group enriched" "Detected in some" 5 "glioma: 0.9;ovarian cancer: 0.5;renal cancer: 1.6;thyroid cancer: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "U-87 MG: 13.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075016 Approved Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA075016: AB_2686729" "unprognostic (1.13e-1)" "unprognostic (3.47e-2)" "unprognostic (1.47e-1)" "unprognostic (6.44e-2)" "unprognostic (1.03e-1)" "unprognostic (6.53e-2)" "unprognostic (2.65e-1)" "unprognostic (1.32e-2)" "unprognostic (2.03e-1)" "unprognostic (1.64e-3)" "unprognostic (2.85e-1)" "unprognostic (6.62e-2)" "unprognostic (5.17e-2)" "unprognostic (1.89e-1)" "unprognostic (1.71e-1)" "unprognostic (3.89e-2)" "unprognostic (5.69e-2)" 9.3 1.2 8.3 0.1 11.9 0.0 0.1 19.9 22.5 3.9 0.0 1.5 0.2 0.8 2.3 0.1 1.9 0.0 0.8 11.2 2.9 9.4 0.2 0.5 0.3 6.1 4.4 1.3 0.1 0.2 8.4 0.0 5.9 1.0 0.0 0.6 0.2 0.3 0.1 0.1 0.5 0.0 1.0 0.9 0.6 0.7 9.6 0.1 13.0 0.0 0.0 0.5 0.8 11.0 0.0 0.9 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.3 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 13.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 11.9 19.9 22.5 11.2 2.9 6.1 4.4 5.9 1.0 9.6 11.0 0.0 0.0 0.6 2.6 0.0 0.0 0.5 0.0 0.0 7.7 0.1 0.0 1.6 0.0 0.0 27.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.4 1.3 0.0 0.0 37.1 0.0 0.0 2.7 0.0 0.8 1.3 0.0 0.0 0.0 0.2 3.3 13.1 0.0 0.0 0.0 0.0 0.3 0.6 0.1 0.0 5.6 0.0 1.7 0.0 2.0 2.9 0.1 0.0 1.9 0.0 0.6 0.0 8.2 0.0 3.3 0.0 0.9 0.6 0.0 0.1 0.0 0.1 0.1 0.0 2.0 0.1 0.8 GAPDH GAPD ENSG00000111640 "Glyceraldehyde-3-phosphate dehydrogenase" P04406 12 6534512-6538374 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Glycolysis, Immunity, Innate immunity, Translation regulation" "Oxidoreductase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 27580.7;tongue: 18892.5" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 10357.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "CAB005197, CAB016392, HPA040067, HPA061280, CAB079968" Supported Enhanced "Nuclear membrane,Vesicles,Plasma membrane,Cytosol" No No 1400000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "Nuclear membrane, Vesicles" "CAB005197: AB_641107, CAB016392: AB_627678, CAB079968: , HPA040067: AB_10965903, HPA061280: AB_2684463" "unprognostic (3.03e-1)" "unprognostic (2.62e-3)" "unprognostic (3.58e-2)" "unprognostic (4.20e-1)" "unprognostic (9.73e-3)" "unprognostic (1.77e-3)" "prognostic unfavorable (1.79e-6)" "unprognostic (2.89e-3)" "unprognostic (2.86e-1)" "unprognostic (2.06e-2)" "unprognostic (9.50e-3)" "unprognostic (4.52e-1)" "prognostic unfavorable (6.25e-10)" "unprognostic (2.33e-1)" "unprognostic (4.28e-1)" "unprognostic (1.40e-1)" "unprognostic (1.26e-2)" 1219.9 1815.8 2605.9 1191.3 2589.5 4608.5 1042.3 2869.0 3067.8 1163.8 2419.2 1720.0 1480.8 1080.9 769.9 2973.8 1042.8 1161.3 5572.8 2630.1 2880.0 2323.2 2557.9 1137.9 1388.3 2845.2 2861.3 1087.0 652.0 1616.0 1338.7 1190.6 2828.4 1241.0 1586.6 2386.8 1835.8 1238.7 27580.7 1775.5 1457.5 1424.4 2670.8 1208.5 1215.5 693.0 2985.1 1570.9 1022.1 18892.5 1861.0 1889.0 1672.9 2741.6 6063.0 10247.9 3109.5 4709.2 3026.2 5018.7 6516.0 4716.2 7218.1 7172.8 7491.2 7211.3 4091.6 7540.8 878.2 5947.4 4904.2 3359.8 3372.7 10829.1 5432.4 6263.1 3229.5 4224.9 5857.5 6279.2 3890.9 6710.2 3046.1 4089.0 3521.7 6553.0 7609.7 15565.8 7762.7 5052.4 2215.9 1484.1 8670.0 11849.8 7303.1 3247.3 10995.7 7254.7 3950.7 5849.8 5505.7 3512.8 7909.6 7115.9 2088.3 3331.0 4243.1 10206.4 5984.0 8874.7 1657.2 4311.2 4794.3 5049.0 5907.2 2717.1 7931.5 3178.4 2544.6 9374.4 10632.2 4050.5 8040.5 2575.4 4295.8 737.9 1325.8 2011.2 1171.4 1046.9 1364.8 1333.1 3253.6 652.5 757.6 886.9 1981.4 1227.8 1900.6 474.6 2126.1 6812.0 2605.9 2589.5 2869.0 3067.8 2630.1 2880.0 2845.2 2861.3 2828.4 2670.8 2985.1 2741.6 1036.7 237.2 259.5 228.2 1086.9 1818.8 2223.4 7367.5 4070.9 1157.6 1794.6 3689.2 40.4 1263.9 2213.7 1022.5 417.0 4237.7 1032.7 2579.6 3463.0 5198.9 759.8 770.1 702.4 1597.4 1324.3 1180.6 112.1 3794.5 10357.8 1127.1 1068.8 1021.8 562.3 2063.7 1242.9 1742.3 3895.3 2348.7 145.8 2351.2 2543.1 2586.7 2494.4 2257.7 889.4 2134.0 4220.8 86.2 3422.3 6177.9 1045.4 98.5 196.2 5681.8 3001.4 1026.9 2668.2 1714.0 5714.0 7286.7 864.3 1435.2 1150.4 1744.7 2827.8 429.9 476.2 3605.2 1600.7 4694.0 1514.9 1839.0 3140.9 2882.4 GAPT "C5orf29, FLJ33641" ENSG00000175857 "GRB2 binding adaptor protein, transmembrane" Q8N292 5 58491435-58497090 "Predicted intracellular proteins" "B-cell activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 16.9;lymphoid tissue: 42.7" "Cell type enhanced" "Detected in some" "B-cells: 84.8;dendritic cells: 160.1;granulocytes: 55.0;Macrophages: 43.0;monocytes: 41.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "eosinophil: 1000.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 1000.3" "Cell line enhanced" "Detected in some" "HEL: 71.5;HL-60: 41.8;NB-4: 43.3;THP-1: 33.7;U-937: 118.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA011048, HPA011070" Uncertain Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA011048: , HPA011070: AB_1848887" "unprognostic (9.79e-2)" "unprognostic (5.67e-3)" "unprognostic (2.39e-2)" "unprognostic (3.26e-2)" "unprognostic (3.36e-2)" "unprognostic (8.09e-4)" "unprognostic (4.32e-1)" "unprognostic (1.23e-3)" "unprognostic (4.14e-2)" "unprognostic (9.47e-3)" "unprognostic (7.28e-2)" "unprognostic (2.93e-1)" "unprognostic (3.52e-3)" "unprognostic (3.74e-2)" "unprognostic (2.42e-2)" "unprognostic (2.33e-2)" "unprognostic (1.40e-2)" 1.7 0.8 0.7 28.5 0.7 16.9 2.3 0.7 1.1 2.7 1.3 2.7 3.7 1.3 1.1 2.1 1.6 5.7 0.7 0.7 1.0 0.8 2.0 4.2 25.3 1.3 1.1 0.4 1.1 1.1 0.6 1.0 1.3 1.8 3.8 0.5 1.9 1.2 0.2 0.8 6.6 4.7 1.0 18.2 3.7 0.7 1.1 6.9 0.6 0.7 42.7 6.0 0.5 1.8 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 71.5 0.2 0.0 0.0 41.8 12.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 43.3 0.0 0.0 0.0 17.7 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 33.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 118.4 0.0 125.5 66.7 1000.3 0.4 46.5 0.5 97.0 0.4 0.4 76.8 97.4 0.3 0.3 82.0 1.4 59.3 205.4 0.3 32.0 0.7 0.7 0.7 1.1 0.7 1.0 1.3 1.1 1.3 1.0 1.1 1.8 0.4 3.2 1.9 0.0 84.8 0.0 0.0 0.0 0.0 0.0 1.0 0.9 0.2 0.0 0.6 0.0 0.0 0.0 160.1 0.0 0.0 0.0 1.6 0.0 0.1 0.9 0.0 8.8 0.0 0.0 0.1 0.4 0.5 0.0 55.0 0.0 0.4 0.0 14.3 0.0 0.0 0.0 0.0 19.4 6.0 0.5 0.0 43.0 0.0 1.9 41.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.0 GARNL3 "bA356B19.1, DKFZp761J1523" ENSG00000136895 "GTPase activating Rap/RanGAP domain like 3" Q5VVW2 9 127224265-127393660 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 77.1;Excitatory neurons: 178.4;Inhibitory neurons: 184.7;Microglial cells: 48.7;Oligodendrocyte precursor cells: 45.2;Oligodendrocytes: 165.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "OE19: 5.3;SH-SY5Y: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028757, HPA074886" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 21: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Nucleoplasm "HPA028757: AB_2294383, HPA074886: AB_2732270" "unprognostic (3.15e-2)" "unprognostic (7.19e-2)" "unprognostic (2.25e-2)" "unprognostic (3.40e-2)" "unprognostic (3.12e-2)" "unprognostic (1.19e-3)" "unprognostic (5.58e-3)" "unprognostic (3.00e-2)" "unprognostic (1.97e-1)" "unprognostic (4.24e-3)" "unprognostic (6.88e-4)" "unprognostic (2.22e-1)" "unprognostic (3.23e-7)" "unprognostic (6.39e-2)" "unprognostic (6.60e-2)" "unprognostic (7.04e-3)" "unprognostic (1.78e-5)" 3.1 6.0 5.7 0.3 5.7 0.0 4.4 11.6 6.0 6.0 2.0 2.9 1.8 7.4 5.2 4.4 5.4 3.7 11.3 6.9 5.2 2.1 1.8 2.4 1.3 4.7 4.5 4.5 2.1 6.6 2.0 1.4 5.8 6.2 1.9 1.3 5.0 4.0 1.5 2.8 1.8 6.7 4.6 1.8 1.8 2.9 4.2 0.6 5.7 1.8 1.3 4.6 3.3 11.2 0.5 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.3 0.1 1.0 1.2 0.3 0.0 1.0 0.1 0.4 0.6 1.8 0.0 0.1 0.0 0.8 0.0 1.9 1.2 0.4 0.4 0.1 0.1 1.5 0.0 0.0 1.5 0.7 1.9 0.8 0.7 0.1 0.5 0.0 0.3 0.4 5.3 1.6 0.1 1.1 3.4 1.9 2.5 1.2 3.9 0.8 2.7 0.4 0.6 0.9 0.0 0.0 0.2 1.0 0.0 0.4 2.3 2.4 1.0 0.4 0.5 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 0.0 1.0 0.1 0.0 5.7 5.7 11.6 6.0 6.9 5.2 4.7 4.5 5.8 4.6 4.2 11.2 1.3 0.0 0.0 77.1 0.5 2.7 1.7 0.4 2.8 8.0 3.1 4.3 6.8 4.3 2.0 3.7 0.0 0.6 0.2 0.9 1.9 0.3 2.2 1.0 21.1 1.5 1.2 0.4 178.4 0.6 0.1 4.8 5.6 1.2 0.0 2.4 1.8 2.5 0.8 1.7 184.7 0.8 0.0 1.3 1.9 1.0 7.5 1.3 1.8 48.7 0.0 4.0 0.0 45.2 165.3 0.4 1.6 3.4 0.5 3.3 0.6 1.8 0.1 1.0 0.0 7.1 4.0 3.5 3.9 2.7 2.0 0.3 0.7 1.0 0.8 1.2 GASK1A "C3orf41, DKFZP434B172, FAM198A" ENSG00000144649 "Golgi associated kinase 1A" Q9UFP1 3 42979267-43060211 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.4;Extravillous trophoblasts: 2.6;Fibroblasts: 1.8;Hofbauer cells: 3.9;Syncytiotrophoblasts: 2.7" "Cancer enhanced" "Detected in many" "glioma: 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 3.1;RPMI-8226: 3.4;SK-BR-3: 2.6;T-47d: 6.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047726 Approved Supported Vesicles "Secreted - unknown location" NA NA 600000 "Cluster 15: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA047726: AB_10960554" "unprognostic (2.16e-3)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (2.93e-2)" "unprognostic (7.48e-2)" "unprognostic (2.18e-2)" "unprognostic (1.65e-2)" "unprognostic (5.79e-2)" "unprognostic (2.69e-1)" "unprognostic (6.21e-2)" "unprognostic (2.02e-1)" "unprognostic (1.50e-1)" "unprognostic (1.57e-4)" "unprognostic (4.45e-2)" "unprognostic (2.09e-2)" "unprognostic (3.49e-2)" "unprognostic (3.81e-1)" 5.5 2.1 4.9 2.5 6.4 0.0 4.2 6.3 3.8 10.6 4.9 3.4 0.7 9.8 2.2 1.8 11.3 5.3 1.7 4.1 5.9 1.0 13.1 3.1 0.7 8.8 7.7 6.8 2.0 0.1 3.0 2.0 7.6 2.6 1.0 3.9 2.6 2.2 1.4 1.7 2.1 6.0 6.3 0.9 3.4 2.9 10.0 0.6 2.1 0.8 0.3 3.2 3.9 5.2 0.0 0.0 0.0 3.1 0.1 0.0 1.1 0.2 0.3 0.0 0.0 0.1 0.9 0.0 1.0 0.0 1.6 0.0 0.3 0.0 0.0 0.0 1.9 0.7 0.0 0.0 0.6 0.4 1.2 0.8 0.0 0.4 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.8 0.0 1.9 0.0 0.0 0.0 0.0 3.4 0.0 0.5 0.1 0.3 0.0 2.6 0.0 0.1 6.7 0.9 0.0 0.4 0.6 1.4 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.9 6.4 6.3 3.8 4.1 5.9 8.8 7.7 7.6 6.3 10.0 5.2 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.8 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 GCG "GLP-1, GLP1, GLP2, GRPP" ENSG00000115263 Glucagon P01275 2 162142882-162152404 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "pancreas: 1943.6" "Cell type enriched" "Detected in some" 23 "Enteroendocrine cells: 5457.0" "Cancer enriched" "Detected in some" 209 "pancreatic cancer: 428.4" "Region enriched" "Detected in single" 55 "medulla oblongata: 6.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 133.4;U-2 OS: 186.8;U-698: 44.5" "Region enriched" "Detected in single" 10 "pons and medulla: 3.5" "Region enriched" "Detected in some" 5 "spinal cord: 13.7" "CAB000040, HPA036760, HPA036761" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to blood" NA NA 127000 420000 "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Endoplasmic reticulum" Vesicles "CAB000040: AB_10013726, HPA036760: AB_2675296, HPA036761: AB_2675297" "unprognostic (3.13e-3)" "unprognostic (9.99e-2)" "unprognostic (1.16e-2)" "unprognostic (1.26e-2)" 20.3 0.1 0.0 3.0 0.0 20.0 0.0 0.0 0.0 0.0 0.0 84.4 3.4 0.6 0.0 5.3 0.0 4.1 2.5 0.0 0.0 41.9 0.0 0.2 3.5 6.2 0.0 0.1 1943.6 0.0 0.0 0.1 0.1 0.8 151.9 0.0 0.3 0.0 0.0 37.2 130.2 0.8 0.0 0.2 41.2 0.0 0.0 0.4 0.6 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 133.4 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 186.8 0.2 12.1 0.0 5.6 44.5 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.2 0.0 0.0 0.3 0.1 5457.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 91.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.0 230.9 8.5 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 22.9 0.0 GCM1 "GCMA, hGCMa" ENSG00000137270 "Glial cells missing transcription factor 1" Q9NP62 6 53126961-53148841 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "placenta: 20.2" "Group enriched" "Detected in some" 7 "Extravillous trophoblasts: 230.3;Syncytiotrophoblasts: 266.1" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 5 "BEWO: 39.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA011343, HPA073469" Enhanced Approved Vesicles NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "HPA011343: AB_2668489, HPA073469: " "unprognostic (2.81e-2)" "unprognostic (4.09e-2)" "unprognostic (1.89e-2)" "unprognostic (1.53e-1)" "unprognostic (3.17e-1)" "unprognostic (7.68e-2)" "unprognostic (8.47e-3)" "unprognostic (2.83e-2)" "unprognostic (2.81e-1)" "unprognostic (4.04e-2)" "unprognostic (1.42e-1)" "unprognostic (5.98e-2)" "unprognostic (1.29e-4)" "unprognostic (1.86e-1)" "unprognostic (7.42e-2)" "unprognostic (2.96e-2)" 0.1 0.1 0.4 0.1 0.2 0.4 0.1 0.3 0.7 0.0 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.1 0.3 0.1 1.3 0.0 0.1 0.3 0.1 0.1 0.1 0.1 0.0 0.0 20.2 0.2 0.0 0.0 0.4 0.1 0.0 3.6 0.1 0.1 0.0 0.0 0.4 0.1 0.6 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.3 0.1 0.1 0.2 0.2 0.0 0.0 39.2 0.0 0.0 0.0 0.0 1.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.2 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.2 0.0 0.1 0.0 8.2 0.1 0.2 0.0 0.1 0.2 0.1 0.1 0.4 0.3 0.2 0.0 0.1 0.1 0.2 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 1.4 0.1 0.1 0.0 0.0 0.0 0.4 0.2 0.3 0.7 0.3 0.1 0.1 0.1 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.7 0.1 0.3 0.0 0.0 0.0 0.0 33.8 0.0 0.0 0.0 0.3 2.0 0.4 0.0 0.4 0.0 0.0 0.1 0.2 230.3 0.5 0.0 0.6 0.0 0.0 0.0 0.0 6.6 0.0 0.1 0.0 0.0 0.0 0.7 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 11.7 0.0 0.0 0.0 0.5 0.1 0.1 0.1 0.0 0.0 266.1 0.1 0.0 0.0 0.1 GCNT3 "C2/4GnT, C2GnT-M, C2GnT2" ENSG00000140297 "Glucosaminyl (N-acetyl) transferase 3, mucin type" O95395 15 59594875-59640239 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 75.5;intestine: 142.9;salivary gland: 55.8" "Cell type enhanced" "Detected in many" "Collecting duct cells: 104.8;Distal enterocytes: 360.1;Ductal cells: 92.6;Glandular and luminal cells: 75.6;Paneth cells: 163.2;Proximal enterocytes: 85.5" "Group enriched" "Detected in many" 4 "colorectal cancer: 16.4;pancreatic cancer: 29.8;stomach cancer: 20.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 147.4;EFO-21: 24.6;Hep G2: 30.3;OE19: 75.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA011154 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" Vesicles "HPA011154: AB_1078961" "unprognostic (5.09e-2)" "unprognostic (2.39e-1)" "unprognostic (5.92e-2)" "prognostic favorable (1.78e-4)" "unprognostic (3.99e-3)" "unprognostic (2.02e-2)" "prognostic unfavorable (6.49e-5)" "unprognostic (1.69e-1)" "unprognostic (1.31e-1)" "unprognostic (2.34e-1)" "unprognostic (1.64e-2)" "unprognostic (1.63e-1)" "unprognostic (4.02e-3)" "unprognostic (1.48e-1)" "unprognostic (1.06e-2)" "unprognostic (4.65e-2)" "unprognostic (2.43e-1)" 0.2 0.7 0.2 11.9 0.2 0.5 0.4 0.6 0.4 19.2 0.2 142.9 97.5 2.0 0.0 15.8 4.2 75.5 0.1 0.2 0.1 17.9 0.4 0.7 0.9 0.1 0.4 0.1 2.1 0.9 0.1 0.1 0.2 1.2 123.2 0.1 55.8 0.3 0.2 0.3 123.3 4.6 0.0 0.1 25.8 4.3 0.2 1.3 2.1 0.0 10.6 9.1 29.9 0.4 0.1 147.4 0.0 0.2 0.0 1.0 0.2 0.1 7.7 0.0 0.0 6.3 6.0 0.6 24.6 0.0 9.5 0.5 0.0 0.0 0.0 0.5 0.1 0.0 0.5 30.3 0.0 0.2 0.2 0.3 3.5 0.7 0.0 0.1 0.0 0.2 0.0 0.4 1.4 0.6 0.1 0.2 0.2 75.9 0.3 0.4 0.0 0.6 10.2 1.2 0.2 0.2 0.0 0.2 0.4 0.1 0.1 0.0 0.1 0.2 0.4 7.3 0.1 0.2 0.5 0.8 8.9 0.3 0.1 0.9 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.7 0.2 0.1 0.3 0.1 0.0 0.2 0.2 0.6 0.4 0.2 0.1 0.1 0.4 0.2 0.0 0.2 0.4 0.0 0.0 2.2 0.0 1.0 0.0 18.3 8.9 0.0 0.0 0.5 0.0 0.7 11.5 40.5 104.8 0.0 0.0 0.1 360.1 0.0 92.6 9.8 23.3 8.6 0.3 7.8 0.0 0.0 14.9 0.0 0.2 27.5 75.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 26.9 8.2 0.6 0.0 19.2 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 58.4 163.2 0.0 0.1 8.0 85.5 4.4 9.8 0.0 6.6 0.6 1.5 3.0 0.3 1.4 0.0 0.0 0.8 0.0 48.5 52.4 GCNT7 "C20orf105, dJ1153D9.2" ENSG00000124091 "Glucosaminyl (N-acetyl) transferase family member 7" Q6ZNI0 20 56491492-56525925 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "bone marrow: 4.4" "Cell type enhanced" "Detected in some" "Early spermatids: 2.2;Excitatory neurons: 1.4;Inhibitory neurons: 1.2;Late spermatids: 1.0;Oligodendrocyte precursor cells: 3.0;Oligodendrocytes: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA052617, HPA059403" Uncertain Approved "Nuclear bodies,Vesicles,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear bodies, Vesicles" Cytosol "HPA052617: AB_2681886, HPA059403: " "unprognostic (3.57e-2)" "unprognostic (1.39e-1)" "unprognostic (7.74e-2)" "unprognostic (1.89e-1)" "unprognostic (3.96e-2)" "unprognostic (9.08e-2)" "unprognostic (3.10e-1)" "unprognostic (1.13e-2)" "unprognostic (4.38e-2)" "unprognostic (2.38e-1)" "unprognostic (9.69e-2)" "unprognostic (2.84e-2)" "unprognostic (2.16e-3)" "unprognostic (1.84e-1)" "unprognostic (1.74e-1)" "unprognostic (1.96e-1)" "unprognostic (8.69e-2)" 0.0 0.1 0.1 0.3 0.2 4.4 0.0 0.6 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.1 0.0 0.2 0.4 0.1 0.0 0.1 0.2 0.1 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.1 0.2 0.1 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.2 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.4 0.2 0.1 0.2 0.2 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.1 0.1 0.3 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.9 0.0 0.1 0.2 0.2 0.0 0.1 0.2 0.6 0.2 0.1 0.2 0.3 0.2 0.3 0.1 0.4 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.2 0.0 0.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 GCSH ENSG00000140905 "Glycine cleavage system protein H" P23434 16 81081945-81096395 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 553.4;Extravillous trophoblasts: 1476.4;Proximal tubular cells: 655.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA041368, HPA057079" Supported Approved Vesicles "Intracellular and membrane" NA NA 50000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "HPA041368: AB_10804001, HPA057079: " "unprognostic (4.09e-2)" "unprognostic (2.98e-2)" "unprognostic (2.29e-1)" "unprognostic (2.47e-3)" "unprognostic (2.55e-3)" "unprognostic (4.87e-2)" "unprognostic (1.38e-1)" "unprognostic (1.67e-1)" "unprognostic (2.75e-1)" "unprognostic (1.96e-2)" "unprognostic (6.92e-2)" "unprognostic (2.80e-2)" "prognostic favorable (6.26e-6)" "unprognostic (1.12e-2)" "unprognostic (2.59e-1)" "unprognostic (6.31e-2)" "unprognostic (6.47e-2)" 28.7 20.1 58.9 6.9 66.5 6.3 24.2 62.9 113.8 18.2 50.8 16.0 7.2 17.5 68.9 15.5 19.8 11.7 38.1 55.8 60.9 78.2 118.9 10.8 6.7 60.1 66.0 18.4 19.7 31.0 14.3 26.0 61.1 18.7 13.0 15.6 15.6 16.7 59.3 10.1 9.5 11.8 61.7 6.3 17.5 7.4 63.7 10.4 96.4 63.6 9.3 18.3 15.2 67.8 63.6 28.3 82.4 37.0 40.4 30.9 175.5 35.9 26.4 43.3 20.6 37.0 57.2 17.2 32.3 15.9 31.9 33.3 64.5 36.5 71.6 4.7 86.7 21.8 34.9 114.6 45.7 70.3 24.1 32.0 47.8 26.8 53.7 13.0 22.3 45.1 86.3 3.4 42.9 67.7 45.9 138.8 113.0 49.6 57.5 72.7 44.1 25.5 98.4 56.4 43.7 45.3 53.3 32.9 70.8 63.9 48.3 33.2 19.8 27.6 49.3 44.0 37.8 14.7 31.8 102.1 18.2 41.3 22.6 3.6 1.3 1.3 2.8 2.1 4.6 3.5 2.6 4.0 3.9 2.5 4.4 5.9 1.7 7.0 1.7 10.8 2.2 2.4 58.9 66.5 62.9 113.8 55.8 60.9 60.1 66.0 61.1 61.7 63.7 67.8 31.1 3.2 5.9 16.3 24.8 29.1 94.6 73.6 52.3 43.7 97.9 115.6 12.9 44.3 31.4 80.9 37.5 553.4 13.8 15.3 295.4 70.0 32.4 34.8 128.3 31.9 26.4 71.1 12.6 42.5 1476.4 61.6 31.1 55.2 36.3 38.5 33.2 352.0 118.8 38.7 11.9 34.3 67.1 19.7 34.6 19.5 140.8 18.8 85.4 4.7 17.7 215.8 19.6 19.6 35.2 42.3 17.8 141.1 51.7 123.9 13.7 655.9 20.0 45.7 32.9 46.2 50.2 20.7 77.3 78.4 27.1 228.8 16.3 114.5 49.4 69.8 GDE1 MIR16 ENSG00000006007 "Glycerophosphodiester phosphodiesterase 1" Q9NZC3 16 19501693-19522123 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 270.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077420 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "Nucleoplasm, Plasma membrane" "HPA077420: " "unprognostic (1.69e-1)" "unprognostic (5.13e-2)" "prognostic favorable (3.12e-4)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (7.52e-5)" "unprognostic (2.10e-2)" "unprognostic (1.40e-2)" "unprognostic (4.31e-2)" "unprognostic (2.60e-3)" "unprognostic (9.92e-2)" "prognostic favorable (3.12e-5)" "unprognostic (8.36e-2)" "unprognostic (9.69e-3)" "unprognostic (1.88e-1)" "unprognostic (3.36e-2)" 28.9 25.9 42.9 15.6 46.3 27.8 21.1 42.9 49.9 21.9 40.4 44.9 30.0 20.0 27.5 22.4 16.9 18.4 52.8 45.7 45.5 27.6 25.4 29.3 11.7 44.5 47.7 12.8 28.5 76.8 19.2 20.5 43.3 26.7 41.6 19.8 28.3 30.3 62.9 26.4 27.7 26.5 42.8 13.5 34.3 14.1 48.8 16.8 20.3 64.4 15.3 30.2 16.6 47.4 38.6 46.2 25.0 29.4 115.3 43.3 34.7 38.3 66.9 30.0 37.1 26.6 67.4 29.2 48.1 57.2 32.8 31.8 35.2 46.6 36.9 31.7 52.8 24.2 41.4 57.2 69.1 32.7 21.5 44.9 73.1 32.2 37.4 54.5 40.6 36.3 13.7 29.1 33.2 70.3 28.3 29.1 29.1 59.9 34.2 40.2 45.7 41.7 72.9 59.7 28.9 25.8 37.0 44.5 37.9 38.5 45.8 37.8 42.7 25.3 22.3 33.9 24.6 27.0 27.4 19.9 38.5 47.2 23.1 52.0 19.3 11.2 8.9 17.7 11.5 7.2 10.4 10.4 12.4 6.1 5.5 8.5 34.0 6.6 22.7 7.5 12.7 8.2 42.9 46.3 42.9 49.9 45.7 45.5 44.5 47.7 43.3 42.8 48.8 47.4 12.2 38.5 86.8 7.2 18.9 23.5 30.3 56.2 22.8 15.4 38.3 22.4 66.8 34.3 56.0 9.2 27.1 80.4 23.2 123.1 23.5 97.0 35.1 26.9 23.8 17.7 33.5 100.8 12.0 163.9 78.6 27.3 24.5 21.5 3.8 36.4 20.7 23.9 60.8 32.0 15.9 57.5 61.1 48.2 22.9 61.2 28.6 32.3 24.9 8.4 38.2 22.3 24.7 9.5 25.0 77.4 97.6 38.0 19.6 100.5 101.7 45.9 39.7 29.6 13.1 16.7 24.9 87.1 59.6 31.9 29.5 270.4 22.0 45.9 85.3 79.2 GDF10 BMP-3b ENSG00000266524 "Growth differentiation factor 10" P55107 10 47300197-47313577 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 19.6;retina: 18.4" "Group enriched" "Detected in some" 5 "Bipolar cells: 20.9;Cone photoreceptor cells: 16.7;Fibroblasts: 25.7;Rod photoreceptor cells: 34.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 13.5;MOLT-4: 3.0;SH-SY5Y: 5.5" "Region enriched" "Detected in all" 8 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA015498 Uncertain Approved Vesicles "Secreted in other tissues" NA NA "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA015498: AB_1849584" "unprognostic (4.34e-2)" "unprognostic (3.10e-1)" "unprognostic (1.41e-1)" "unprognostic (5.09e-1)" "unprognostic (3.17e-1)" "unprognostic (9.84e-3)" "unprognostic (1.37e-2)" "unprognostic (2.26e-2)" "unprognostic (1.55e-1)" "unprognostic (4.08e-2)" "unprognostic (1.15e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-7)" "unprognostic (3.49e-2)" "unprognostic (1.48e-1)" "unprognostic (2.59e-3)" "unprognostic (2.63e-1)" 12.4 3.2 5.4 0.3 5.4 0.0 9.7 5.1 4.0 2.6 0.6 2.5 0.0 4.2 0.2 2.4 1.6 2.2 4.4 5.9 3.3 0.1 0.1 19.6 0.8 2.6 5.8 0.3 13.3 0.0 0.7 0.0 1.4 2.2 0.3 18.4 8.8 0.2 2.2 3.1 0.6 0.4 2.5 0.1 1.8 7.1 5.5 0.4 9.7 10.4 1.0 1.3 1.7 3.7 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 3.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 5.4 5.1 4.0 5.9 3.3 2.6 5.8 1.4 2.5 5.5 3.7 2.4 0.0 0.6 0.0 0.0 0.4 0.1 0.0 0.0 20.9 0.1 0.0 0.8 0.0 0.0 0.0 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.6 0.2 25.7 0.0 0.0 1.3 0.0 0.0 0.0 0.1 1.7 0.0 0.2 0.0 0.0 2.6 0.7 0.9 0.2 1.8 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.8 0.0 0.6 1.6 0.4 1.3 0.0 0.9 0.0 0.4 0.0 0.0 0.0 GDF11 "BMP-11, BMP11" ENSG00000135414 "Growth differentiation factor 11" O95390 12 55743122-55757264 "Predicted secreted proteins" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 26.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 76.6;Cone photoreceptor cells: 77.2;Horizontal cells: 57.2;Rod photoreceptor cells: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HMC-1: 127.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060985, HPA069609" Approved Approved Vesicles "Secreted to blood" No No 46400 340000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 3: HMC-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA060985: AB_2684403, HPA069609: AB_2686159" "unprognostic (5.21e-2)" "unprognostic (1.62e-1)" "unprognostic (3.20e-2)" "unprognostic (2.41e-2)" "unprognostic (2.78e-2)" "unprognostic (3.39e-1)" "unprognostic (2.13e-1)" "unprognostic (2.62e-2)" "unprognostic (8.96e-3)" "unprognostic (1.23e-2)" "prognostic favorable (1.08e-4)" "unprognostic (2.69e-1)" "unprognostic (1.62e-2)" "unprognostic (1.27e-1)" "unprognostic (3.13e-1)" "unprognostic (1.01e-3)" "unprognostic (9.48e-2)" 3.6 4.0 22.5 3.7 17.5 1.8 2.3 16.4 17.8 6.8 15.9 5.4 1.6 7.6 2.0 2.4 5.0 4.6 7.5 18.1 18.5 3.0 1.3 3.6 2.8 22.0 26.6 5.7 2.9 2.9 4.7 2.0 20.9 6.0 1.6 21.6 4.8 9.4 1.8 1.5 3.7 4.6 18.3 5.6 2.7 1.1 22.3 4.6 3.6 2.0 1.8 5.9 3.4 17.7 4.9 7.6 32.8 18.6 24.4 17.8 8.2 10.1 9.5 12.5 10.7 26.0 2.1 9.5 13.0 10.5 5.9 4.6 25.0 18.0 4.3 18.2 22.7 11.7 12.3 4.1 4.9 9.8 127.7 17.2 1.0 18.3 5.2 14.0 16.4 12.7 13.2 30.1 16.0 9.2 16.0 8.5 26.4 0.3 18.9 25.1 8.9 5.9 7.7 6.6 22.2 13.6 6.2 2.8 2.6 13.3 10.7 10.7 10.1 15.0 22.9 11.9 7.4 8.1 2.6 4.9 8.0 9.7 10.8 0.2 0.2 0.5 1.2 0.1 1.0 0.7 0.7 0.7 0.2 0.7 0.6 0.8 0.3 0.2 0.4 0.7 0.5 0.1 22.5 17.5 16.4 17.8 18.1 18.5 22.0 26.6 20.9 18.3 22.3 17.7 8.4 0.0 1.1 19.2 10.9 0.5 9.8 0.6 4.0 76.6 6.3 6.6 25.6 1.5 0.9 0.0 77.2 3.6 16.6 1.5 0.0 5.0 0.6 9.9 35.2 8.0 10.7 11.1 4.3 1.4 5.3 13.3 3.1 18.0 5.7 7.6 6.4 0.2 1.6 57.2 10.8 1.9 0.0 1.9 0.7 0.8 9.0 4.4 3.6 1.9 4.1 30.6 22.6 17.1 3.2 3.3 4.1 5.7 4.1 9.8 3.4 0.5 0.1 53.1 13.1 31.1 18.1 2.9 4.1 3.0 0.9 4.7 18.9 7.2 2.2 6.2 GDF6 "BMP13, KFS, KFS1, SGM1" ENSG00000156466 "Growth differentiation factor 6" Q6KF10 8 96142333-96160806 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Cytokine, Developmental protein, Growth factor" "Disease variant, Dwarfism, Leber congenital amaurosis, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 10.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.3;Distal tubular cells: 1.9;Excitatory neurons: 1.6;Fibroblasts: 3.1;Oligodendrocyte precursor cells: 7.1;Spermatogonia: 2.4" "Cancer enhanced" "Detected in some" "renal cancer: 2.8;thyroid cancer: 2.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTERT-RPE1: 20.4;LHCN-M2: 33.1;SuSa: 15.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "midbrain: 1.2" HPA045206 Uncertain Supported "Nucleoplasm,Nuclear membrane,Vesicles" "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Nuclear membrane" "HPA045206: AB_10962508" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (1.83e-2)" "unprognostic (9.66e-9)" "unprognostic (6.49e-2)" "unprognostic (1.47e-1)" "unprognostic (1.41e-1)" "unprognostic (3.18e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-3)" "unprognostic (5.37e-2)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.17e-4)" "unprognostic (5.88e-4)" "unprognostic (1.88e-2)" "unprognostic (2.68e-2)" "unprognostic (1.71e-1)" 1.3 0.1 0.3 0.9 0.3 0.0 0.4 0.4 0.8 0.2 0.0 0.7 0.3 1.4 0.4 0.4 0.5 2.4 2.8 0.3 0.4 0.2 0.4 0.2 0.1 0.8 0.4 0.1 0.7 0.1 0.1 10.9 1.0 0.3 0.3 0.0 0.0 1.4 0.0 0.0 0.9 1.1 0.4 0.0 0.6 0.6 0.8 0.1 0.6 0.0 0.0 0.8 0.9 0.4 0.0 0.0 0.2 0.0 1.1 0.6 3.9 2.6 0.0 2.3 2.0 0.0 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 3.2 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.1 0.0 3.0 0.0 20.4 0.2 0.0 0.0 0.0 33.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.8 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.4 0.8 0.3 0.4 0.8 0.4 1.0 0.4 0.8 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.8 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 1.0 2.4 0.0 0.0 0.3 0.1 0.0 0.0 0.1 GDF7 BMP12 ENSG00000143869 "Growth differentiation factor 7" Q7Z4P5 2 20667144-20679243 "Predicted secreted proteins" "Cytokine, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 9.8;seminal vesicle: 22.4" "Group enriched" "Detected in some" 12 "Endometrial stromal cells: 137.0;Granulosa cells: 83.7" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebral cortex: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 1.7;Hep G2: 4.4;RT4: 8.3;SH-SY5Y: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA069106 Approved Vesicles "Secreted in other tissues" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 15: RT4 - Unknown function" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA069106: " "unprognostic (1.35e-1)" "unprognostic (9.93e-3)" "unprognostic (5.10e-1)" "unprognostic (2.44e-3)" "unprognostic (1.35e-1)" "unprognostic (2.06e-3)" "unprognostic (8.63e-3)" "unprognostic (6.31e-3)" "unprognostic (8.00e-3)" "unprognostic (3.85e-1)" "unprognostic (4.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.28e-3)" "unprognostic (8.02e-3)" "unprognostic (2.05e-1)" "unprognostic (3.44e-2)" "unprognostic (1.89e-3)" 0.4 0.4 0.2 1.0 0.5 0.2 0.1 0.0 2.5 9.8 0.0 0.5 0.2 7.2 3.3 0.9 0.7 0.6 0.8 0.4 0.1 3.6 5.0 0.4 2.3 0.3 0.1 0.3 0.6 0.1 0.3 0.8 0.0 3.8 0.2 0.1 0.1 22.4 0.0 1.3 1.6 1.1 0.0 1.3 0.7 0.2 0.3 0.2 0.2 0.6 1.8 1.1 6.6 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.7 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.1 1.2 8.3 0.0 3.3 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 2.5 0.4 0.1 0.3 0.1 0.0 0.0 0.3 0.6 0.1 6.4 0.0 0.0 2.6 0.0 0.6 0.0 0.0 0.5 0.0 0.0 8.8 2.8 3.1 5.5 0.0 0.0 0.1 0.1 1.9 0.1 0.1 3.5 137.0 1.8 0.0 2.7 0.2 0.0 0.1 1.3 0.0 2.9 0.0 83.7 0.0 8.2 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.7 0.0 4.1 0.7 0.0 0.0 0.3 7.1 0.5 1.0 0.0 0.0 0.0 0.8 0.0 0.0 1.5 GDNF "ATF1, ATF2, HFB1-GDNF" ENSG00000168621 "Glial cell derived neurotrophic factor" P39905 5 37812677-37840041 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes, Disease variant, Hirschsprung disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 8.2;skeletal muscle: 10.1" "Cell type enhanced" "Detected in some" "Fibroblasts: 3.3;Skeletal myocytes: 11.5;Spermatogonia: 3.4;Theca cells: 2.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTEC/SVTERT24-B: 41.4;SuSa: 12.6;U-87 MG: 12.6;WM-115: 46.5" "Region enhanced" "Detected in single" "basal ganglia: 2.8" "Low region specificity" "Detected in some" "CAB005210, HPA070283" Supported Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 37: Myocytes - Muscle contraction" Vesicles Nucleoplasm "CAB005210: AB_2247684, HPA070283: AB_2686246" "unprognostic (1.08e-1)" "unprognostic (6.30e-2)" "unprognostic (3.54e-2)" "unprognostic (8.87e-2)" "unprognostic (1.09e-1)" "unprognostic (1.08e-1)" "unprognostic (5.33e-2)" "unprognostic (1.92e-1)" "unprognostic (3.71e-2)" "unprognostic (2.01e-2)" "unprognostic (2.41e-1)" "unprognostic (2.10e-1)" "unprognostic (1.16e-4)" "unprognostic (2.04e-1)" "unprognostic (8.86e-2)" "unprognostic (1.05e-1)" "unprognostic (4.42e-2)" 0.1 0.4 2.3 1.6 1.5 0.1 0.3 5.8 1.4 0.8 0.0 8.2 1.4 1.3 2.5 0.9 0.9 0.9 0.8 0.6 1.6 0.9 0.7 0.0 0.1 0.7 3.1 3.6 0.0 0.0 0.1 5.0 1.0 1.3 2.4 0.3 0.2 4.5 10.1 1.3 2.0 2.1 0.2 0.4 1.6 0.4 6.1 0.1 0.1 4.3 0.0 0.7 0.8 2.9 0.0 0.0 0.1 0.1 1.8 1.0 0.0 5.5 3.4 1.1 1.6 0.0 0.1 0.1 0.0 7.4 0.1 0.2 0.0 0.1 2.2 0.0 0.2 0.0 0.4 0.5 0.2 0.1 0.1 1.8 0.1 41.4 0.0 1.4 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.1 0.4 0.1 0.0 0.1 9.0 0.0 0.0 0.2 0.5 0.0 0.3 0.2 2.7 12.6 0.1 0.0 0.0 5.5 0.0 1.4 6.2 4.0 0.0 0.0 12.6 0.0 46.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.3 1.5 5.8 1.4 0.6 1.6 0.7 3.1 1.0 0.2 6.1 2.9 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.0 0.6 0.6 0.0 0.3 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.2 0.0 0.1 3.3 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 1.5 0.6 0.0 0.0 0.4 0.0 0.2 0.0 0.7 0.1 0.0 0.0 11.5 1.8 0.9 3.4 0.0 0.3 0.1 0.0 2.6 0.0 0.5 GFPT2 GFAT2 ENSG00000131459 "Glutamine-fructose-6-phosphate transaminase 2" O94808 5 180300698-180353336 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 112.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 30.4;Fibroblasts: 77.9;Skeletal myocytes: 27.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 3.5" "Lineage enriched" "Detected in single" 35 "T-cells: 3.5" "Cell line enhanced" "Detected in many" "ASC diff: 119.1;ASC TERT1: 202.3;GAMG: 152.5;HSkMC: 130.7;hTEC/SVTERT24-B: 248.0;U-87 MG: 426.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056892, HPA059910" Uncertain Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA056892: AB_2683266, HPA059910: AB_2684157" "unprognostic (3.48e-1)" "prognostic unfavorable (9.09e-4)" "unprognostic (1.91e-2)" "unprognostic (1.08e-2)" "unprognostic (6.28e-2)" "unprognostic (3.39e-3)" "unprognostic (3.05e-1)" "prognostic unfavorable (2.95e-4)" "unprognostic (7.65e-2)" "unprognostic (2.73e-2)" "unprognostic (4.50e-2)" "unprognostic (2.94e-2)" "prognostic unfavorable (2.58e-14)" "unprognostic (3.67e-3)" "unprognostic (1.23e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (1.52e-3)" 112.4 7.0 14.2 18.6 14.8 0.1 23.0 19.7 17.6 24.8 14.1 18.0 1.6 15.9 7.7 5.7 35.8 16.4 27.8 14.9 16.8 6.8 2.1 25.2 2.8 27.8 15.7 33.4 12.4 4.6 5.1 6.5 21.5 15.6 3.2 2.9 7.1 8.2 4.6 8.4 11.3 11.3 16.8 1.9 14.6 8.6 15.7 1.2 10.8 7.1 3.5 38.3 17.9 20.4 0.1 27.7 21.5 28.0 119.1 202.3 2.3 3.5 0.7 2.3 0.8 0.7 0.1 0.0 1.4 23.2 152.5 0.4 11.8 0.2 1.4 2.6 4.2 0.0 13.7 0.0 49.4 0.0 0.2 130.7 1.0 248.0 0.7 41.7 40.7 1.0 0.0 0.4 107.7 4.2 0.1 0.0 45.7 0.3 12.3 0.6 0.2 0.0 0.0 0.0 1.0 1.6 43.0 0.8 1.4 25.0 1.9 0.3 19.5 67.9 10.7 44.3 52.2 0.1 0.1 0.0 426.7 0.0 1.5 0.0 0.0 0.0 0.7 0.0 3.5 0.0 0.3 1.2 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.1 14.2 14.8 19.7 17.6 14.9 16.8 27.8 15.7 21.5 16.8 15.7 20.4 4.1 3.2 4.8 13.4 0.8 7.4 0.4 0.2 3.4 0.0 3.2 6.3 3.0 5.7 3.2 1.8 0.0 1.1 3.5 0.4 1.9 1.0 5.7 2.0 30.4 1.9 0.0 0.0 20.0 0.8 0.5 77.9 6.6 1.9 1.3 0.4 1.4 0.0 0.5 0.0 12.1 0.5 0.0 0.3 9.6 3.5 10.2 1.7 8.8 4.7 0.0 6.1 0.0 10.6 6.5 0.4 0.0 18.8 2.5 1.7 0.0 0.4 1.5 0.1 0.0 27.3 17.6 10.1 8.3 1.7 4.3 2.7 8.9 0.0 0.1 0.6 GFRA2 "GDNFRB, NTNRA, RETL2, TRNR2" ENSG00000168546 "GDNF family receptor alpha 2" O00451 8 21690398-21812357 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 9.4;thyroid gland: 8.7" "Group enriched" "Detected in some" 4 "Early spermatids: 91.9;Horizontal cells: 220.4;Late spermatids: 238.1" "Cancer enriched" "Detected in some" 5 "thyroid cancer: 6.2" "Region enhanced" "Detected in many" "cerebral cortex: 5.0" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 9.2" "Group enriched" "Detected in many" 7 "dendritic cells: 2.5;monocytes: 9.2" "Cell line enhanced" "Detected in some" "HEL: 9.1;HMC-1: 21.4;WM-115: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024704, CAB032791" Uncertain Approved Vesicles "Intracellular and membrane" NA NA 9000000 "Cluster 7: Monocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "CAB032791: AB_2110428, HPA024704: AB_1849629" "unprognostic (4.24e-2)" "unprognostic (1.11e-2)" "unprognostic (4.02e-1)" "unprognostic (3.46e-2)" "unprognostic (3.93e-2)" "unprognostic (1.08e-2)" "unprognostic (7.48e-4)" "unprognostic (2.87e-1)" "unprognostic (6.11e-2)" "unprognostic (4.40e-3)" "unprognostic (2.11e-3)" "unprognostic (7.82e-2)" "unprognostic (1.50e-4)" "unprognostic (8.45e-4)" "unprognostic (1.74e-1)" "unprognostic (4.68e-2)" "unprognostic (9.63e-3)" 2.4 1.8 1.2 2.0 1.0 0.6 0.6 0.0 5.0 2.6 0.0 2.1 1.9 0.5 0.2 1.5 1.3 0.6 1.0 1.5 2.2 0.2 0.9 1.2 1.6 0.0 0.8 0.3 0.3 0.1 0.4 7.1 0.0 0.4 1.1 2.6 0.9 1.5 0.1 0.5 1.8 2.0 0.0 7.5 1.0 9.4 1.8 1.1 8.7 0.6 0.8 1.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 1.9 0.8 0.0 9.2 0.0 0.0 0.0 0.0 2.5 0.0 0.1 0.0 0.4 0.0 1.3 0.0 0.0 0.9 1.2 1.0 0.0 5.0 1.5 2.2 0.0 0.8 0.0 0.0 1.8 0.0 0.3 0.0 1.8 1.3 0.1 1.8 0.2 0.0 0.0 4.3 0.1 0.4 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 91.9 0.0 1.2 0.3 0.0 0.0 39.5 0.0 0.1 1.8 0.0 0.1 1.3 0.0 0.7 0.2 0.6 220.4 6.5 0.0 0.0 30.6 25.2 238.1 0.6 11.8 0.0 3.7 0.5 1.9 0.0 2.5 1.1 0.0 0.0 1.9 0.1 0.1 0.0 0.0 0.0 2.1 6.6 0.7 1.8 1.2 7.0 0.0 0.9 0.3 0.2 0.1 0.0 0.1 GGA1 ENSG00000100083 "Golgi associated, gamma adaptin ear containing, ARF binding protein 1" Q9UJY5 22 37608725-37633564 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 179.3" "Cell type enhanced" "Detected in all" "Late spermatids: 221.2;Spermatocytes: 193.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048280, HPA051016" Supported Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 43: Testis - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Golgi apparatus, Vesicles" Nucleoplasm "HPA048280: AB_2680338, HPA051016: AB_2681312" "unprognostic (1.64e-1)" "unprognostic (1.42e-2)" "unprognostic (4.08e-1)" "unprognostic (9.23e-3)" "unprognostic (2.00e-1)" "unprognostic (2.77e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (2.32e-2)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "prognostic favorable (4.86e-4)" "unprognostic (1.42e-2)" "unprognostic (1.53e-2)" "unprognostic (1.14e-2)" "unprognostic (1.19e-1)" "unprognostic (2.22e-1)" "unprognostic (1.16e-3)" 25.0 49.3 35.9 23.3 39.7 37.2 27.3 39.0 42.3 38.0 41.0 35.0 24.3 32.1 21.5 41.1 37.4 20.4 29.5 35.3 35.0 42.4 42.1 33.7 29.1 41.1 37.6 46.3 34.5 33.2 52.7 19.1 38.4 40.0 17.8 22.8 34.9 19.6 43.1 35.7 40.7 16.9 36.1 55.6 34.9 179.3 41.2 26.9 44.7 24.6 21.1 31.6 33.5 45.0 37.4 28.3 32.9 31.1 28.0 23.0 35.4 30.8 25.0 27.0 29.6 23.3 21.8 59.9 20.6 22.9 17.0 35.0 29.4 35.6 24.8 51.0 53.6 24.0 52.3 27.3 28.1 56.1 42.6 28.4 31.3 38.9 24.2 45.1 26.5 30.3 48.0 36.8 27.8 37.7 24.8 64.2 26.2 39.2 28.7 28.5 25.8 25.2 28.8 31.0 30.4 54.0 18.7 39.0 48.9 31.3 42.4 42.0 31.0 36.8 35.2 32.1 24.4 81.1 35.3 62.5 39.9 33.6 30.8 8.1 10.7 6.1 18.0 10.2 22.1 8.3 7.2 23.3 6.7 5.0 5.1 16.5 4.5 11.6 7.9 5.8 8.0 11.5 35.9 39.7 39.0 42.3 35.3 35.0 41.1 37.6 38.4 36.1 41.2 45.0 17.9 25.6 38.5 26.8 50.9 24.2 31.1 36.5 21.1 57.6 26.5 20.8 19.2 20.0 34.5 44.1 83.4 38.8 34.7 67.3 5.9 34.9 148.2 27.6 19.8 32.6 32.4 38.3 18.4 20.1 37.4 18.8 44.4 26.5 49.4 33.3 40.7 20.4 77.1 25.2 19.3 40.4 32.6 66.9 40.3 221.2 26.4 50.5 16.0 20.6 47.9 37.0 73.2 16.6 28.7 36.6 51.6 22.6 24.4 24.7 55.4 13.2 46.7 74.1 26.3 26.9 22.1 193.4 50.4 19.7 28.6 56.8 59.6 44.4 42.8 33.6 GGT1 "CD224, D22S672, D22S732, GGT" ENSG00000100031 "Gamma-glutamyltransferase 1" P19440 22 24594811-24629005 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis, Lipid metabolism" "Acyltransferase, Hydrolase, Protease, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 174.8;liver: 115.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 80.1;Cholangiocytes: 48.6;Distal enterocytes: 54.1;Ductal cells: 82.6;Hepatocytes: 40.8;Proximal enterocytes: 111.7;Proximal tubular cells: 62.9" "Cancer enhanced" "Detected in all" "renal cancer: 37.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 103.6;Karpas-707: 165.8;OE19: 169.5;RPMI-8226: 210.3;RPTEC TERT1: 203.2" "HPA045635, HPA047534, HPA065444" Supported Uncertain Vesicles "Intracellular and membrane" NA NA 3600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA045635: AB_2679400, HPA047534: AB_2680079, HPA065444: AB_2685491" "unprognostic (8.13e-3)" "unprognostic (4.76e-1)" "unprognostic (8.29e-2)" "unprognostic (1.28e-2)" "unprognostic (3.70e-2)" "unprognostic (1.43e-2)" "unprognostic (5.60e-3)" "unprognostic (1.68e-1)" "unprognostic (2.21e-1)" "prognostic favorable (7.44e-4)" "unprognostic (4.55e-2)" "unprognostic (2.55e-2)" "prognostic favorable (4.83e-4)" "unprognostic (1.44e-2)" "unprognostic (5.37e-2)" "unprognostic (1.74e-1)" "unprognostic (6.10e-2)" 3.3 2.4 5.5 6.4 6.7 12.0 24.7 7.0 7.5 28.7 5.1 20.3 84.7 3.0 72.0 3.3 3.3 47.1 7.2 5.1 5.1 174.8 115.7 42.6 5.4 7.2 6.6 3.2 63.1 0.2 5.5 2.4 7.8 48.8 11.0 1.6 9.9 21.6 1.9 4.1 80.4 2.2 5.9 13.3 31.3 18.4 7.1 6.5 15.9 0.4 6.2 5.7 4.3 9.2 1.0 79.7 1.0 0.3 0.0 0.5 2.2 0.5 1.7 0.8 1.0 11.7 18.3 1.0 16.2 0.1 14.8 11.0 6.2 0.8 0.5 103.6 12.3 0.6 40.8 64.3 5.5 1.5 33.2 2.1 0.9 2.5 1.7 1.4 0.5 19.0 8.4 165.8 1.0 1.7 1.6 52.4 6.4 169.5 0.7 0.7 6.8 210.3 203.2 2.9 0.5 1.2 0.4 33.3 0.8 22.2 32.4 39.6 6.4 10.6 9.3 46.6 0.9 48.2 18.4 0.7 19.0 58.7 0.5 4.8 12.3 0.2 1.0 6.0 2.9 2.2 5.0 2.4 6.5 0.2 0.6 1.4 15.9 4.9 4.0 0.1 6.5 5.6 5.5 6.7 7.0 7.5 5.1 5.1 7.2 6.6 7.8 5.9 7.1 9.2 0.2 80.1 22.8 3.3 2.8 0.8 0.1 0.3 4.6 0.5 5.9 2.3 0.7 48.6 4.9 1.8 0.0 1.4 0.7 54.1 1.9 82.6 1.8 1.2 0.6 0.7 1.2 5.3 4.4 8.1 0.4 3.9 15.3 5.1 5.7 0.1 1.8 40.8 4.9 0.0 4.1 4.4 4.1 2.5 1.7 6.7 0.0 2.9 1.8 1.0 5.8 2.5 0.0 1.5 5.7 20.9 20.1 0.4 12.8 2.0 111.7 62.9 1.6 0.1 0.0 0.1 1.0 0.6 0.8 0.4 0.4 0.8 4.0 0.0 6.5 0.1 GGT2 GGT ENSG00000133475 "Gamma-glutamyltransferase 2" P36268 22 21207973-21227637 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "kidney: 8.7;thyroid gland: 8.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 7.2;Early spermatids: 5.6;Late spermatids: 18.7;Proximal tubular cells: 3.4" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 1.6;HeLa: 3.5;Karpas-707: 1.3;U-2197: 8.9" "HPA045635, HPA047534, HPA065444" Supported Uncertain Vesicles NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 18: U-2197 - ECM organization" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA045635: AB_2679400, HPA047534: AB_2680079, HPA065444: AB_2685491" "unprognostic (4.27e-1)" "unprognostic (6.91e-2)" "unprognostic (7.03e-2)" "unprognostic (8.13e-2)" "unprognostic (1.01e-2)" "unprognostic (2.38e-5)" "unprognostic (1.05e-3)" "unprognostic (5.85e-4)" "unprognostic (7.97e-3)" "unprognostic (8.84e-2)" "unprognostic (1.16e-1)" "unprognostic (6.39e-2)" "unprognostic (2.39e-1)" "unprognostic (1.48e-2)" "unprognostic (3.46e-3)" 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.2 0.3 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.1 0.7 0.0 0.2 0.1 0.0 0.2 0.0 0.3 0.0 0.2 0.1 0.0 0.1 1.5 0.0 0.0 0.5 0.4 0.0 0.1 0.0 0.2 1.0 0.1 0.0 8.5 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 1.6 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.6 0.0 0.9 0.0 0.0 0.0 0.3 0.3 8.9 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.1 0.2 0.1 0.1 0.2 0.0 3.2 7.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.6 0.7 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 3.4 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 GGT7 "D20S101, dJ18C9.2, GGTL3, GGTL5" ENSG00000131067 "Gamma-glutamyltransferase 7" Q9UJ14 20 34844720-34872856 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 60.9;Inhibitory neurons: 58.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013204, HPA013339" Approved Approved Nucleoplasm,Vesicles NA NA 1900000 "Cluster 30: Non-specific - Translation" "Cluster 80: Striated muscle - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Nucleoplasm "HPA013204: AB_1850347, HPA013339: AB_2668816" "unprognostic (1.32e-3)" "unprognostic (2.33e-1)" "unprognostic (9.31e-2)" "prognostic unfavorable (1.26e-5)" "unprognostic (1.27e-1)" "unprognostic (6.55e-2)" "unprognostic (1.46e-3)" "unprognostic (2.49e-2)" "unprognostic (3.49e-1)" "unprognostic (1.16e-2)" "unprognostic (3.34e-3)" "unprognostic (3.61e-2)" "unprognostic (5.00e-3)" "unprognostic (1.81e-1)" "unprognostic (1.63e-1)" "unprognostic (5.50e-2)" "unprognostic (2.00e-1)" 13.2 13.8 37.0 11.8 35.8 5.5 15.4 43.4 43.8 25.6 53.2 19.1 16.0 19.3 29.1 10.1 21.1 18.2 22.3 38.6 33.3 24.9 16.8 14.4 18.2 34.3 28.9 24.1 27.1 22.9 40.5 13.7 33.6 24.8 14.9 22.7 30.8 22.6 67.5 17.9 20.1 14.9 22.5 15.4 22.1 10.1 32.0 15.8 28.8 13.8 13.6 19.7 18.0 35.4 5.2 7.7 38.5 39.5 29.7 26.4 34.2 21.7 21.9 17.5 26.0 40.6 25.5 0.0 25.1 17.1 17.8 3.6 16.8 9.5 11.5 1.8 29.9 15.9 16.0 21.3 26.5 0.8 24.9 38.5 10.6 19.7 9.1 52.2 1.5 20.3 12.0 2.8 12.2 9.1 4.2 8.1 8.9 9.1 3.8 0.1 26.3 25.9 25.3 7.7 22.4 26.1 11.2 17.6 28.2 14.4 13.5 14.2 0.6 59.8 23.6 5.7 12.6 29.6 4.2 1.9 70.4 1.5 22.4 1.4 2.8 1.5 6.9 2.0 2.0 6.1 5.8 2.6 2.5 5.4 11.5 8.2 0.3 3.0 0.7 1.4 5.1 1.8 37.0 35.8 43.4 43.8 38.6 33.3 34.3 28.9 33.6 22.5 32.0 35.4 2.0 3.2 2.7 23.2 6.4 7.4 18.1 14.8 9.1 40.2 9.6 5.8 1.9 32.9 11.1 18.4 12.5 24.2 2.2 14.2 0.0 16.1 3.2 3.3 7.6 2.1 10.8 1.7 60.9 5.6 12.3 14.0 23.4 4.5 2.5 9.0 1.4 12.1 4.5 40.4 58.0 15.2 38.7 3.2 4.4 1.8 12.5 3.2 10.6 17.8 2.8 9.7 4.1 31.2 25.5 6.3 17.8 7.9 1.9 9.3 11.9 6.1 7.2 19.3 6.6 16.0 9.4 13.9 15.5 5.7 4.3 16.8 7.2 17.0 17.9 13.9 GIGYF1 "GYF1, PERQ1" ENSG00000146830 "GRB10 interacting GYF protein 1" O75420 7 100679507-100694250 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 100.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020999, HPA023995" Enhanced Approved Vesicles,Microtubules NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 71: Testis - DNA repair" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" Vesicles Microtubules "HPA020999: AB_2111744, HPA023995: AB_1855221" "unprognostic (3.82e-3)" "unprognostic (1.58e-1)" "unprognostic (2.56e-2)" "unprognostic (2.67e-2)" "unprognostic (7.46e-2)" "prognostic favorable (7.42e-4)" "prognostic unfavorable (2.30e-4)" "unprognostic (1.43e-2)" "unprognostic (8.06e-2)" "unprognostic (1.65e-2)" "prognostic favorable (1.35e-5)" "unprognostic (3.66e-2)" "unprognostic (1.32e-2)" "unprognostic (1.53e-1)" "unprognostic (1.89e-1)" "unprognostic (2.79e-1)" "unprognostic (2.67e-3)" 25.7 25.9 21.1 15.6 21.1 30.5 26.9 27.7 24.1 36.1 21.3 26.5 15.8 34.9 11.0 19.1 30.2 10.4 22.4 19.5 17.3 27.3 23.1 22.6 18.9 20.9 18.8 43.4 36.1 13.5 41.9 11.4 18.7 28.5 8.0 8.8 29.6 13.7 26.5 33.5 30.7 11.2 16.2 39.1 25.1 32.2 21.4 17.2 32.8 16.7 11.3 23.5 23.6 24.0 16.5 16.8 26.1 38.2 12.3 9.6 46.6 15.3 12.4 9.4 10.8 9.8 27.6 22.9 19.2 11.1 19.0 19.4 12.9 15.3 5.8 24.4 26.4 15.9 48.5 14.3 12.2 18.1 26.1 15.1 12.2 12.0 17.0 15.3 9.5 26.4 44.8 21.9 8.7 37.5 32.1 100.1 32.0 6.5 20.1 51.2 13.9 23.1 6.9 14.8 23.3 36.7 19.8 31.2 18.2 17.6 14.2 30.2 14.7 26.8 32.9 44.7 14.2 17.8 8.4 12.3 15.6 35.9 16.2 2.2 1.3 1.2 2.4 1.2 1.8 1.3 1.6 1.5 0.5 1.9 1.4 1.5 4.5 1.3 1.3 2.0 0.9 0.5 21.1 21.1 27.7 24.1 19.5 17.3 20.9 18.8 18.7 16.2 21.4 24.0 26.5 3.2 7.8 19.9 18.1 31.7 11.0 5.8 8.0 25.5 25.5 20.6 8.3 32.9 5.8 18.4 18.8 12.0 31.2 19.5 15.6 11.5 1.0 12.2 24.3 17.5 18.6 9.9 18.1 9.4 10.7 17.8 18.8 17.5 5.7 26.5 22.5 19.0 11.4 52.2 17.7 22.8 6.1 25.5 19.8 3.8 24.5 15.6 17.8 29.0 12.5 15.3 20.6 14.6 22.6 11.8 18.0 18.0 10.5 16.7 20.4 9.9 5.0 28.0 32.9 33.2 19.6 16.4 36.0 6.8 22.4 16.3 20.5 12.9 16.1 10.2 GIMAP4 "FLJ11110, HIMAP4, IAN1, IMAP4" ENSG00000133574 "GTPase, IMAP family member 4" Q9NUV9 7 150567369-150573953 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 127.7" "Cell type enhanced" "Detected in many" "Adipocytes: 182.3;Endothelial cells: 195.2;Hepatic stellate cells: 222.0;Kupffer cells: 197.2;Macrophages: 110.0;monocytes: 176.0;NK-cells: 344.0;T-cells: 186.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 26 "HUVEC TERT2: 326.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019135, HPA019137, HPA027198" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Vesicles, Cytosol" "HPA019135: AB_1849670, HPA019137: AB_1849672, HPA027198: AB_10602599" "unprognostic (5.03e-2)" "unprognostic (3.30e-3)" "unprognostic (4.08e-2)" "prognostic favorable (7.63e-4)" "unprognostic (1.72e-1)" "unprognostic (1.73e-2)" "unprognostic (7.00e-2)" "unprognostic (2.40e-2)" "unprognostic (1.87e-2)" "unprognostic (1.05e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.65e-1)" "unprognostic (3.32e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-1)" 46.1 18.3 15.0 75.1 15.6 4.2 31.8 16.2 21.2 19.7 16.3 21.2 16.5 23.0 9.6 12.0 18.7 24.6 31.3 14.3 16.0 17.3 29.9 50.8 127.7 19.2 18.0 7.7 6.7 9.6 6.0 48.7 18.0 10.2 22.4 1.5 11.2 13.3 17.5 8.4 25.0 38.3 18.8 115.6 18.0 4.2 16.4 30.5 21.1 48.1 85.1 31.1 11.6 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 326.4 3.4 0.1 0.3 0.0 0.0 0.4 0.2 0.4 0.0 0.0 12.7 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.5 370.2 5.2 325.8 390.9 404.2 3.0 408.0 402.8 122.1 1.3 424.3 361.9 339.7 263.4 320.4 5.3 312.1 776.9 15.0 15.6 16.2 21.2 14.3 16.0 19.2 18.0 18.0 18.8 16.4 18.7 182.3 3.2 12.4 0.3 7.3 6.8 0.2 0.0 3.4 0.1 2.2 4.7 9.9 5.7 1.8 11.0 0.0 0.6 82.6 0.0 0.0 0.2 0.6 0.3 0.4 195.2 0.0 9.7 0.5 0.2 0.8 9.0 2.0 0.3 6.3 0.0 222.0 3.7 96.4 0.0 0.1 0.0 0.0 197.2 20.9 1.7 5.0 110.0 10.6 18.7 176.0 0.2 344.0 0.0 0.1 0.1 0.0 0.0 14.7 0.4 0.0 1.9 0.7 0.4 13.1 3.9 7.9 0.0 0.8 1.1 6.1 0.8 186.2 0.8 0.0 0.3 GIMAP7 "IAN7, MGC27027" ENSG00000179144 "GTPase, IMAP family member 7" Q8NHV1 7 150514872-150521073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 170.1" "Cell type enhanced" "Detected in many" "Adipocytes: 265.8;Endothelial cells: 263.3;Hepatic stellate cells: 267.4;Kupffer cells: 156.8;monocytes: 140.8;NK-cells: 632.4;T-cells: 255.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "monocytes: 666.6;NK-cells: 1121.0;T-cells: 2269.3" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 92.9;MOLT-4: 78.6" "Not detected" "Not detected" "HPA020266, HPA020268" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus, Vesicles" "HPA020266: AB_1849680, HPA020268: AB_1849682" "unprognostic (4.85e-3)" "unprognostic (1.65e-3)" "unprognostic (6.11e-2)" "unprognostic (1.32e-2)" "unprognostic (3.71e-1)" "prognostic favorable (7.43e-4)" "prognostic favorable (8.98e-5)" "unprognostic (6.49e-3)" "unprognostic (5.24e-2)" "unprognostic (6.12e-3)" "unprognostic (2.36e-2)" "unprognostic (2.81e-1)" "unprognostic (2.07e-3)" "unprognostic (2.07e-1)" "unprognostic (3.14e-2)" "unprognostic (2.01e-1)" "unprognostic (8.86e-2)" 49.8 15.0 16.3 73.6 17.4 6.6 37.4 17.1 21.3 19.2 16.0 20.3 21.1 27.8 19.8 12.6 21.5 22.1 40.1 15.5 17.2 20.9 20.4 61.0 170.1 19.0 17.8 7.4 7.6 10.5 5.6 31.5 19.1 10.9 23.3 1.2 13.7 12.0 27.8 9.3 40.1 33.6 17.6 124.3 22.0 4.5 18.0 52.5 28.2 56.1 99.2 29.6 13.0 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 92.9 9.4 0.0 0.0 0.0 0.0 78.6 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.7 656.5 9.6 1184.0 595.9 1164.2 6.5 1762.9 1440.6 286.3 6.5 2269.3 1597.2 52.5 1121.0 666.6 16.3 1076.9 2581.7 16.3 17.4 17.1 21.3 15.5 17.2 19.0 17.8 19.1 17.6 18.0 17.6 265.8 0.0 13.2 0.3 13.1 2.4 0.4 0.0 2.8 0.0 2.8 5.6 14.6 5.7 0.6 1.8 0.0 0.2 125.1 0.2 0.0 0.5 1.3 0.9 0.6 263.3 0.0 17.0 0.0 0.7 0.0 8.0 3.1 0.7 13.9 0.0 267.4 5.3 15.5 0.0 0.0 0.1 0.0 156.8 10.6 2.0 2.5 54.9 1.8 22.5 140.8 0.4 632.4 0.5 0.1 0.4 1.2 0.4 19.3 0.2 0.0 1.7 0.7 0.4 0.0 6.0 9.4 0.2 0.9 1.1 3.3 0.4 255.9 0.9 0.2 0.0 GIPR ENSG00000010310 "Gastric inhibitory polypeptide receptor" P48546 19 45668221-45683722 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 22.7" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 29.9;Gastric mucus-secreting cells: 28.1;Respiratory ciliated cells: 44.5;Rod photoreceptor cells: 17.4" "Cancer enriched" "Detected in many" 5 "pancreatic cancer: 4.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HDLM-2: 9.8;HMC-1: 20.6;SCLC-21H: 13.9;U-266/70: 16.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB022710, HPA068054" Uncertain Uncertain Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 3: HMC-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "CAB022710: , HPA068054: " "unprognostic (2.40e-2)" "unprognostic (9.03e-2)" "unprognostic (2.24e-1)" "unprognostic (1.31e-2)" "unprognostic (2.65e-1)" "unprognostic (3.70e-4)" "unprognostic (1.82e-2)" "unprognostic (2.94e-2)" "unprognostic (1.42e-1)" "unprognostic (1.72e-2)" "unprognostic (4.85e-3)" "unprognostic (2.78e-1)" "unprognostic (1.72e-2)" "unprognostic (1.19e-1)" "unprognostic (1.37e-1)" "unprognostic (3.37e-2)" "unprognostic (2.59e-2)" 10.0 0.3 1.8 3.1 2.6 2.0 9.0 2.3 3.3 2.5 2.7 6.9 3.7 0.3 0.7 2.5 10.2 1.4 15.2 1.8 2.7 3.8 0.7 5.6 2.7 4.1 4.7 0.1 10.8 5.6 0.4 0.2 4.5 7.1 4.9 13.1 7.8 0.4 0.3 4.2 4.2 0.3 1.7 4.0 22.7 0.2 4.4 0.6 2.5 0.0 2.4 2.6 3.4 4.4 0.7 0.4 1.3 0.7 0.6 0.0 0.1 1.0 0.8 0.0 0.7 0.4 3.9 1.9 0.6 0.8 0.7 2.0 0.3 0.2 0.1 9.8 0.3 1.6 1.0 0.3 0.1 0.6 20.6 0.0 0.3 0.1 0.0 1.8 0.0 2.1 4.5 2.2 0.0 0.2 0.1 1.1 0.0 2.9 0.7 0.5 0.4 4.4 0.5 0.9 13.9 1.2 0.0 0.8 0.2 0.5 2.0 3.1 0.4 0.0 0.5 0.3 0.2 16.7 0.2 0.4 0.6 1.5 0.3 1.1 0.1 0.5 0.5 0.2 0.1 0.2 0.2 0.3 0.2 0.3 0.2 0.3 0.5 0.9 0.0 0.2 0.4 0.2 1.8 2.6 2.3 3.3 1.8 2.7 4.1 4.7 4.5 1.7 4.4 4.4 1.4 3.2 6.3 0.0 1.0 0.9 3.4 2.9 0.0 0.3 2.0 0.5 4.0 5.7 9.8 5.5 0.0 0.0 3.7 13.2 0.0 2.2 0.4 7.1 0.1 0.5 29.9 0.0 0.2 3.6 0.1 0.5 28.1 0.7 1.3 0.1 0.0 0.0 0.1 0.0 0.4 6.8 4.1 0.0 7.8 0.2 0.0 1.4 0.0 0.0 0.5 0.2 1.0 0.0 5.0 5.6 11.3 0.0 4.0 1.5 0.3 0.1 44.5 17.4 13.1 0.3 3.5 0.2 0.3 1.5 0.4 0.1 2.1 0.1 1.9 2.8 GJA1 "CX43, GJAL, ODD, ODDD, ODOD, SDTY3" ENSG00000152661 "Gap junction protein alpha 1" P17302 6 121435595-121449727 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cancer-related genes, Cataract, Disease variant, Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 250.0;Astrocytes: 276.2;Basal keratinocytes: 234.9;Cardiomyocytes: 199.7;Endometrial stromal cells: 215.5;Granulosa cells: 494.3;Suprabasal keratinocytes: 378.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 462.7;HUVEC TERT2: 362.3;NTERA-2: 365.8;SuSa: 453.4;U-87 MG: 350.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB010753, HPA035097, HPA047551, HPA069245" Enhanced Supported Supported "Nucleoplasm,Vesicles,Cell Junctions" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Cell Junctions" Nucleoplasm "CAB010753: AB_476857, HPA035097: AB_2674460, HPA047551: AB_2732540, HPA069245: " "unprognostic (3.37e-2)" "unprognostic (3.41e-3)" "unprognostic (2.95e-1)" "unprognostic (4.18e-2)" "unprognostic (1.48e-2)" "unprognostic (1.67e-2)" "unprognostic (1.27e-1)" "unprognostic (6.78e-2)" "unprognostic (2.89e-2)" "unprognostic (1.56e-1)" "unprognostic (5.47e-2)" "unprognostic (1.00e-1)" "unprognostic (4.88e-2)" "prognostic unfavorable (4.99e-5)" "unprognostic (2.39e-1)" "unprognostic (1.29e-1)" "unprognostic (3.00e-3)" 121.2 287.6 313.5 24.7 310.2 0.9 60.6 260.1 409.0 261.7 193.1 17.5 18.2 98.7 10.6 74.9 32.7 99.9 168.9 273.6 362.6 21.2 10.6 67.9 21.1 340.3 380.9 43.5 19.4 236.2 31.3 290.2 307.4 83.3 19.7 3.3 35.6 148.0 10.3 388.2 24.7 112.5 335.9 4.2 30.7 36.9 373.3 24.3 169.1 22.1 34.9 116.0 184.9 341.0 0.1 43.5 186.8 0.4 99.7 61.5 0.4 142.5 286.9 46.9 113.7 0.7 0.4 0.0 15.8 55.8 40.2 18.3 5.1 87.4 151.3 0.1 51.6 2.3 15.7 0.0 124.1 0.0 0.4 164.6 92.1 172.5 61.7 462.7 362.3 0.0 0.1 4.3 9.4 8.4 0.1 80.6 365.8 0.1 47.2 0.1 0.0 3.7 188.6 21.0 0.4 2.9 0.0 0.3 0.1 453.4 14.9 0.3 269.5 143.8 39.4 122.8 93.5 0.1 0.1 0.1 350.4 0.1 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 313.5 310.2 260.1 409.0 273.6 362.6 340.3 380.9 307.4 335.9 373.3 341.0 152.2 250.0 80.0 276.2 0.1 234.9 133.6 71.1 77.4 0.3 9.5 20.1 199.7 0.0 17.5 1.8 2.1 53.4 0.4 0.0 0.0 76.9 0.5 21.5 215.5 166.6 0.0 0.0 0.3 4.2 7.9 124.4 0.5 51.7 8.8 494.3 33.9 0.1 8.6 0.0 0.6 0.0 4.1 0.9 55.3 1.7 2.5 3.6 44.4 15.0 0.6 0.3 0.0 4.0 1.0 10.8 0.0 4.1 0.1 29.7 0.0 0.1 6.2 0.3 0.0 5.9 80.2 0.9 1.8 68.3 378.2 20.0 4.9 127.1 0.4 52.7 GJB3 "CX31, DFNA2, EKV" ENSG00000188910 "Gap junction protein beta 3" O75712 1 34781214-34786369 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 77.8;skin 1: 145.0" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 138.4;Basal prostatic cells: 71.9;Basal respiratory cells: 43.6;Pancreatic endocrine cells: 119.8;Prostatic glandular cells: 63.4;Squamous epithelial cells: 91.9;Suprabasal keratinocytes: 170.6;Urothelial cells: 171.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 58.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 88.8;CAPAN-2: 121.7;HaCaT: 99.4;HBEC3-KT: 84.9;hTCEpi: 136.8;OE19: 54.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA074472 Supported "Vesicles,Cell Junctions" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Cell Junctions" "HPA074472: AB_2686694" "unprognostic (1.34e-3)" "unprognostic (2.30e-1)" "unprognostic (2.84e-2)" "unprognostic (5.22e-3)" "unprognostic (3.82e-2)" "unprognostic (2.00e-2)" "unprognostic (1.21e-4)" "prognostic unfavorable (4.56e-4)" "unprognostic (2.30e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (7.56e-5)" "unprognostic (4.50e-2)" "unprognostic (5.74e-3)" "unprognostic (1.35e-1)" "unprognostic (1.22e-1)" "unprognostic (1.27e-2)" "unprognostic (2.46e-2)" 0.3 0.2 1.3 1.7 0.6 0.0 5.5 1.1 1.0 8.9 0.0 4.2 0.2 0.3 2.8 77.8 1.1 7.0 0.1 0.6 0.0 0.5 1.5 0.6 0.5 0.2 0.0 0.1 0.3 0.0 0.1 1.4 0.1 4.0 5.0 0.0 8.9 1.7 0.6 145.0 1.3 0.1 0.0 0.0 5.9 0.8 0.1 0.8 0.2 0.0 12.9 11.9 26.4 0.2 88.8 2.6 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 121.7 0.0 11.6 0.1 0.1 99.4 0.0 84.9 0.0 0.1 0.0 0.3 5.0 0.0 0.0 0.0 0.0 0.0 136.8 0.0 35.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.4 54.2 22.3 0.0 0.0 0.0 40.8 33.0 0.0 0.0 13.1 0.9 0.0 0.1 1.0 0.1 0.0 0.1 5.7 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.6 1.1 1.0 0.6 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.0 3.2 0.0 0.0 0.0 138.4 71.9 43.6 16.5 0.0 2.0 1.3 0.4 1.5 15.5 5.5 0.0 0.3 0.0 18.3 0.0 14.6 0.0 4.1 0.4 1.7 1.8 0.0 0.2 7.3 0.2 1.7 3.1 8.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 6.1 0.0 12.5 0.0 0.0 0.4 14.2 0.0 0.0 0.0 0.0 0.0 0.0 119.8 8.1 0.0 0.0 63.4 0.5 0.0 10.1 0.0 0.0 0.0 2.1 0.1 0.3 91.9 170.6 0.1 0.5 0.0 19.1 171.0 GLB1 "EBP, ELNR1" ENSG00000170266 "Galactosidase beta 1" P16278 3 32996609-33097202 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 857.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008382, HPA040610, HPA069503" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 2700000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles "Golgi apparatus" "CAB008382: AB_590642, HPA040610: AB_2677039, HPA069503: AB_2686142" "unprognostic (1.51e-2)" "unprognostic (3.66e-2)" "unprognostic (5.02e-3)" "unprognostic (9.66e-3)" "unprognostic (9.61e-3)" "unprognostic (1.04e-1)" "unprognostic (2.31e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (2.06e-1)" "unprognostic (2.08e-1)" "prognostic favorable (1.14e-5)" "unprognostic (3.05e-1)" "unprognostic (2.33e-1)" "unprognostic (2.20e-1)" "unprognostic (5.85e-2)" 22.0 36.1 12.1 27.8 13.0 21.9 20.5 12.5 14.8 33.4 16.0 43.5 43.0 21.9 103.6 15.4 28.2 32.0 15.5 12.5 14.8 46.0 48.2 42.7 25.8 14.3 12.9 21.4 30.8 59.4 18.5 53.8 15.4 23.2 45.6 14.9 25.3 29.3 7.7 15.8 31.0 30.6 12.4 24.4 35.5 13.5 13.5 17.5 52.8 10.8 23.0 31.8 16.2 15.1 37.4 63.6 39.8 48.3 241.9 123.7 857.2 59.1 157.6 73.7 95.1 91.3 86.5 17.9 50.9 120.9 53.9 35.1 38.1 75.5 53.7 104.9 33.0 69.9 35.3 47.4 124.3 50.5 69.9 144.9 70.2 67.0 39.2 144.1 116.5 24.7 64.3 67.0 81.8 44.6 29.6 31.6 26.4 78.0 27.0 24.7 26.4 86.6 78.4 54.4 12.0 40.3 75.0 120.2 74.4 69.3 80.3 130.2 67.7 46.8 32.2 65.2 50.1 53.2 87.9 5.9 99.6 71.2 36.7 43.9 146.2 86.4 29.2 125.8 40.4 37.9 34.3 31.8 166.5 35.6 17.9 21.8 56.6 26.0 92.1 35.1 77.1 91.9 12.1 13.0 12.5 14.8 12.5 14.8 14.3 12.9 15.4 12.4 13.5 15.1 8.7 19.2 25.3 39.2 18.6 6.0 13.6 60.1 10.8 11.3 11.5 7.5 9.1 34.3 43.3 27.6 6.2 100.1 14.1 41.9 27.4 53.5 24.8 18.7 16.0 17.4 16.9 20.6 46.7 35.4 55.3 29.2 26.0 27.1 26.6 20.6 19.6 39.7 79.5 5.0 46.0 23.5 40.7 43.9 13.9 5.0 15.2 41.7 14.2 23.4 64.6 16.5 10.3 27.2 24.2 28.1 43.4 21.1 19.8 9.9 36.2 33.1 31.0 16.2 13.1 12.9 16.3 1.0 6.6 10.1 3.4 49.1 18.7 51.0 32.0 12.1 GLB1L2 ENSG00000149328 "Galactosidase beta 1 like 2" Q8IW92 11 134331874-134378341 "Predicted secreted proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 160.6" "Cell type enriched" "Detected in many" 4 "Rod photoreceptor cells: 182.0" "Cancer enhanced" "Detected in many" "prostate cancer: 21.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.2;NK-cell: 3.1" "Group enriched" "Detected in many" 24 "NK-cells: 3.1;T-cells: 3.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 49.9;HaCaT: 52.6;OE19: 123.6;SCLC-21H: 34.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA054808, HPA059955" Uncertain Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 21: OE19 - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm Vesicles "HPA054808: AB_2682608, HPA059955: AB_2684178" "unprognostic (2.63e-2)" "unprognostic (9.77e-3)" "unprognostic (2.32e-2)" "unprognostic (2.20e-2)" "unprognostic (8.07e-2)" "unprognostic (1.54e-1)" "unprognostic (5.98e-2)" "unprognostic (2.08e-2)" "unprognostic (1.51e-1)" "unprognostic (8.31e-2)" "unprognostic (1.67e-1)" "unprognostic (1.48e-1)" "unprognostic (4.73e-2)" "unprognostic (1.22e-2)" "unprognostic (2.64e-1)" "unprognostic (3.88e-3)" "unprognostic (1.01e-1)" 1.5 2.1 3.0 2.6 2.1 0.3 7.0 0.1 7.7 5.9 14.7 27.6 5.7 33.9 2.1 3.5 25.6 2.8 1.2 8.5 0.3 20.7 0.6 3.6 0.6 1.0 0.8 13.7 10.6 25.0 14.1 1.5 1.0 34.5 11.7 160.6 9.1 25.2 1.0 9.4 4.0 4.4 0.1 0.6 9.0 8.3 0.7 0.5 22.7 0.2 0.6 6.7 5.0 1.3 16.0 1.6 8.2 4.7 0.0 0.0 5.5 0.0 0.0 0.0 0.0 13.3 49.9 0.0 16.3 0.0 6.8 52.6 25.2 0.4 0.0 0.0 23.9 0.0 6.7 0.6 2.2 0.0 28.4 0.3 0.7 0.0 0.0 0.0 0.1 7.6 26.3 0.0 0.0 15.3 4.4 3.0 4.7 123.6 18.2 0.0 0.0 1.5 14.1 11.0 34.9 13.1 11.4 14.2 0.0 1.2 18.4 0.2 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 4.1 0.0 3.1 0.0 0.0 0.0 3.2 0.0 1.2 0.0 0.6 1.2 0.0 0.1 0.9 1.4 0.0 3.1 0.0 0.0 0.0 0.5 3.0 2.1 0.1 7.7 8.5 0.3 1.0 0.8 1.0 0.1 0.7 1.3 0.2 0.0 1.8 0.3 0.4 2.2 5.2 1.0 1.8 6.2 7.2 7.9 1.6 1.5 2.5 0.0 41.7 0.2 3.4 19.5 0.0 2.5 2.1 7.9 22.1 1.2 9.0 0.0 1.6 2.4 1.0 3.6 4.1 2.2 0.0 41.9 0.0 0.2 0.2 5.0 1.2 5.9 0.0 0.0 0.3 6.8 1.2 0.3 5.4 1.0 0.0 10.8 1.0 1.0 0.3 2.2 6.3 0.7 2.2 8.1 3.0 8.4 10.1 182.0 0.0 3.7 2.3 2.6 4.6 1.9 0.9 0.1 2.5 3.4 11.5 2.7 GLDN "CLOM, COLM, colmedin, CRG-L2, UNC-122" ENSG00000186417 Gliomedin Q6ZMI3 15 51341655-51408005 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 84.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 510.8" "Cancer enhanced" "Detected in many" "glioma: 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 2.7;MCF7: 1.3;SuSa: 1.8;U-266/70: 3.3;U-266/84: 2.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA050873, HPA059441" Uncertain Supported "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA 410000 "Cluster 70: Brain - Nervous system development" "Cluster 29: U-266 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" "HPA050873: , HPA059441: AB_2684018" "unprognostic (5.04e-2)" "unprognostic (2.57e-2)" "unprognostic (5.15e-5)" "unprognostic (3.21e-3)" "unprognostic (2.82e-2)" "unprognostic (2.33e-1)" "unprognostic (2.07e-4)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (3.30e-2)" "unprognostic (3.15e-1)" "unprognostic (2.14e-2)" "unprognostic (9.89e-2)" "unprognostic (1.60e-2)" "unprognostic (2.20e-1)" "unprognostic (3.80e-3)" "unprognostic (1.37e-1)" 18.5 2.3 18.1 1.6 51.1 0.7 9.7 35.0 28.6 1.8 0.0 3.5 0.2 0.5 0.5 0.5 1.2 3.4 5.0 15.5 31.2 0.4 0.1 8.7 0.2 47.6 48.9 0.5 0.5 0.4 0.6 3.9 56.4 2.4 6.4 1.3 1.4 0.7 1.0 5.0 0.6 0.6 26.0 2.9 2.1 0.2 41.7 0.1 0.8 0.9 0.2 1.5 1.5 84.8 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 2.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.1 0.0 0.1 0.5 0.8 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.0 1.0 0.0 1.8 0.0 0.5 0.0 0.0 0.0 0.1 0.0 3.3 2.9 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 18.1 51.1 35.0 28.6 15.5 31.2 47.6 48.9 56.4 26.0 41.7 84.8 40.1 0.0 2.6 2.0 0.0 6.2 0.0 0.3 0.0 9.2 0.2 0.3 8.4 0.0 0.1 0.0 0.0 5.2 0.0 47.0 0.0 0.0 0.0 0.0 0.1 3.7 1.2 0.0 7.4 0.0 0.6 7.9 4.6 0.2 0.0 4.5 0.0 0.2 4.9 0.0 17.2 1.7 0.0 14.9 9.5 0.0 0.3 16.1 3.6 42.2 0.0 0.3 0.0 2.0 510.8 0.1 28.6 0.0 0.0 0.1 0.0 0.1 0.9 0.8 0.0 4.7 9.8 0.1 0.1 0.0 4.0 100.4 0.6 0.4 5.1 1.6 GLI3 "ACLS, GCPS, PAP-A, PAPA, PAPA1, PAPB, PHS, PPDIV" ENSG00000106571 "GLI family zinc finger 3" P10071 7 41960949-42264100 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 8 "Astrocytes: 301.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 47.1;WM-115: 34.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005534 Approved Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm "Nucleoli, Vesicles" "HPA005534: AB_1078973" "unprognostic (2.53e-1)" "unprognostic (2.41e-2)" "unprognostic (7.58e-2)" "unprognostic (8.22e-3)" "unprognostic (1.10e-1)" "unprognostic (1.28e-2)" "unprognostic (1.01e-1)" "unprognostic (5.35e-3)" "unprognostic (2.24e-1)" "unprognostic (7.38e-2)" "unprognostic (4.03e-1)" "unprognostic (3.54e-2)" "unprognostic (1.48e-5)" "unprognostic (9.13e-3)" "unprognostic (5.41e-2)" "unprognostic (3.21e-3)" "unprognostic (7.00e-2)" 6.1 1.9 9.2 3.6 8.8 0.1 8.9 1.0 5.4 7.2 0.0 11.6 1.2 11.8 2.7 3.7 8.2 3.8 1.6 6.3 5.5 1.7 0.3 3.4 0.9 1.7 10.4 13.2 0.7 0.5 1.1 11.9 3.0 5.5 2.9 1.8 2.8 8.2 1.1 8.3 3.4 10.7 0.5 1.1 2.6 1.7 14.4 3.0 4.6 2.3 1.7 4.8 7.3 2.3 0.0 0.0 47.1 0.4 16.9 23.6 3.5 3.1 9.0 9.3 12.8 0.0 0.0 0.0 1.7 22.1 22.7 10.1 8.7 8.9 10.8 0.0 7.0 0.0 6.0 0.0 9.0 0.0 0.1 21.0 12.9 10.6 6.8 5.7 10.6 5.4 0.0 0.2 5.6 5.6 0.4 0.0 20.9 0.0 21.2 12.4 0.1 1.4 0.2 6.4 1.5 0.0 6.3 7.0 4.1 23.8 8.0 0.1 11.3 13.6 18.8 16.0 6.0 0.1 0.0 0.0 7.3 0.2 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 8.8 1.0 5.4 6.3 5.5 1.7 10.4 3.0 0.5 14.4 2.3 2.9 0.0 7.7 301.3 0.2 23.5 7.2 8.5 31.9 1.6 20.5 27.1 1.8 0.0 2.3 1.8 0.0 21.1 0.5 0.0 0.0 0.0 16.6 2.4 12.6 3.4 0.0 0.0 0.8 0.0 13.6 25.9 0.0 4.6 1.3 10.5 3.9 0.0 3.3 0.0 3.6 0.1 6.1 0.3 6.3 5.4 19.3 0.4 8.8 22.5 0.0 13.6 0.0 8.5 0.7 0.1 0.0 3.4 1.2 6.6 0.0 3.8 1.5 1.1 13.1 17.0 12.1 0.3 2.2 7.9 15.5 34.2 0.7 5.2 0.1 5.0 GLIPR1L2 MGC39497 ENSG00000180481 "GLIPR1 like 2" Q4G1C9 12 75391089-75432688 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 46.8" "Group enriched" "Detected in many" 7 "Early spermatids: 254.0;Spermatocytes: 306.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "Hep G2: 4.2;SK-BR-3: 5.6;U-2 OS: 7.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039795, HPA039866" Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 78: Testis - Spermatogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Golgi apparatus" Vesicles "HPA039795: AB_10805595, HPA039866: AB_10795235" "unprognostic (1.23e-1)" "unprognostic (1.87e-1)" "unprognostic (3.32e-1)" "unprognostic (2.27e-1)" "unprognostic (7.74e-2)" "unprognostic (1.33e-1)" "unprognostic (8.78e-3)" "unprognostic (2.29e-2)" "unprognostic (1.48e-1)" "unprognostic (2.82e-1)" "unprognostic (7.68e-3)" "unprognostic (1.20e-1)" "unprognostic (1.10e-1)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (5.91e-2)" "unprognostic (2.57e-2)" 1.0 2.7 5.1 0.8 5.2 0.3 2.4 6.5 5.9 2.1 2.5 0.9 0.6 2.3 3.7 1.0 3.1 1.0 2.3 5.5 5.0 2.0 1.5 1.2 0.7 4.0 4.3 7.1 2.6 4.1 2.6 0.9 4.4 1.5 0.4 3.0 1.0 3.0 2.3 1.9 0.8 1.1 4.0 1.6 0.7 46.8 4.7 1.3 2.4 1.6 0.4 0.9 0.9 6.3 0.2 0.4 0.2 0.4 2.9 1.6 0.5 0.4 0.3 0.1 0.2 0.1 0.3 0.2 1.0 0.3 0.7 0.1 0.0 0.1 0.3 0.6 0.2 0.1 0.6 4.2 2.1 0.4 0.0 0.5 0.9 0.4 1.5 2.5 0.1 0.1 0.2 0.5 0.8 0.1 0.4 0.3 0.1 0.9 0.1 0.1 0.0 0.2 0.0 0.3 0.7 0.3 0.5 5.6 1.7 0.2 1.7 0.1 0.8 0.6 7.6 0.9 0.3 0.7 0.7 0.2 0.2 0.2 0.5 0.7 0.0 0.1 0.3 0.0 0.1 0.3 0.3 0.5 0.1 0.3 0.5 0.9 0.6 0.3 0.1 0.7 1.0 0.2 5.1 5.2 6.5 5.9 5.5 5.0 4.0 4.3 4.4 4.0 4.7 6.3 1.5 0.0 3.1 15.0 0.3 0.9 4.6 1.7 3.4 5.6 2.9 3.0 4.0 1.5 1.8 0.0 0.0 1.7 1.5 0.1 9.8 0.6 254.0 4.9 1.4 1.5 0.0 0.4 7.4 0.0 0.2 3.0 1.1 0.5 1.3 1.4 0.0 0.2 0.6 1.7 13.3 0.1 0.0 0.3 0.3 39.0 7.5 0.7 0.0 10.3 0.0 6.7 0.0 27.2 28.1 0.1 0.0 5.7 0.1 1.2 0.1 1.4 14.1 2.0 6.6 5.6 1.9 306.8 19.4 0.3 0.4 0.4 0.6 2.1 0.3 2.1 GLIPR2 "C9orf19, GAPR-1" ENSG00000122694 "GLI pathogenesis related 2" Q9H4G4 9 36136536-36163913 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 188.5;Langerhans cells: 203.6;Macrophages: 117.6;monocytes: 203.0;NK-cells: 180.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 71.6;HDLM-2: 72.9;TIME: 127.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029478 Approved Uncertain Vesicles,Microtubules NA NA 19000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Vesicles Microtubules "HPA029478: AB_10670038" "unprognostic (1.57e-2)" "unprognostic (5.70e-3)" "unprognostic (1.54e-1)" "unprognostic (1.28e-1)" "unprognostic (1.46e-2)" "unprognostic (1.33e-2)" "unprognostic (9.90e-2)" "unprognostic (2.50e-1)" "unprognostic (1.84e-2)" "unprognostic (4.26e-2)" "unprognostic (3.21e-1)" "unprognostic (5.87e-2)" "prognostic unfavorable (6.54e-7)" "unprognostic (6.57e-3)" "unprognostic (4.94e-1)" "unprognostic (1.02e-1)" "unprognostic (2.43e-2)" 38.5 20.9 17.6 52.7 22.8 73.8 32.4 21.0 22.6 45.9 14.1 73.7 14.7 77.8 15.1 18.6 36.9 24.1 24.2 17.2 19.3 8.8 6.9 62.6 29.9 24.8 22.1 13.3 5.6 2.5 4.9 8.8 22.3 38.3 33.1 2.7 15.3 39.3 7.7 12.2 32.2 63.8 22.8 41.3 25.3 3.4 26.7 18.7 15.8 11.1 19.2 38.8 27.4 27.6 3.7 2.9 20.9 22.3 71.6 33.3 2.4 32.9 20.0 7.8 14.1 1.3 0.3 0.2 10.2 30.9 19.7 0.2 7.9 1.1 4.7 72.9 6.4 8.8 6.2 0.4 27.9 5.7 28.3 23.4 1.0 44.5 7.8 14.0 62.5 22.6 0.4 5.0 17.4 7.9 27.9 15.2 20.1 0.3 10.7 18.9 44.1 1.0 1.6 1.8 5.6 11.3 4.4 2.2 3.6 42.2 2.3 24.0 127.3 10.7 24.8 9.6 28.0 7.8 2.2 12.7 11.0 35.0 2.5 268.6 360.9 540.3 168.4 162.5 89.1 24.4 114.3 108.2 208.3 24.5 47.0 74.7 657.0 125.5 124.9 18.5 132.2 414.0 17.6 22.8 21.0 22.6 17.2 19.3 24.8 22.1 22.3 22.8 26.7 27.6 11.9 3.2 25.4 4.6 22.3 13.4 2.5 14.7 1.8 0.3 46.9 19.0 2.6 2.8 30.9 5.5 0.0 3.8 66.9 14.7 0.0 21.2 0.7 1.8 33.9 13.3 8.4 58.7 1.1 1.3 3.3 54.3 11.7 2.1 52.6 1.9 16.1 0.9 188.5 0.0 0.8 42.4 14.2 83.2 203.6 2.3 18.0 117.6 62.2 2.8 203.0 21.4 180.2 3.0 28.6 5.2 16.1 25.9 22.8 16.0 4.0 1.1 64.3 0.5 46.0 44.7 43.2 0.9 6.4 0.9 10.2 3.4 75.5 10.9 45.3 3.3 GLRX2 "bA101E13.1, GRX2" ENSG00000023572 "Glutaredoxin 2" Q9NS18 1 193090866-193106114 "Metabolic proteins, Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 17 "Early spermatids: 796.4;Late spermatids: 1841.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 240.2" "Low region specificity" "Detected in all" "HPA023087, HPA057224" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Vesicles "HPA023087: AB_1849778, HPA057224: AB_2683373" "unprognostic (4.80e-2)" "unprognostic (3.77e-2)" "unprognostic (8.04e-2)" "unprognostic (2.33e-1)" "unprognostic (1.13e-1)" "unprognostic (4.99e-2)" "unprognostic (2.40e-3)" "unprognostic (5.11e-2)" "unprognostic (3.21e-2)" "unprognostic (2.38e-2)" "unprognostic (1.10e-2)" "unprognostic (2.38e-1)" "prognostic unfavorable (3.30e-7)" "unprognostic (6.23e-2)" "unprognostic (1.73e-1)" "unprognostic (6.21e-2)" "unprognostic (4.48e-2)" 16.1 22.3 16.0 7.9 16.5 9.5 12.4 17.0 28.7 10.2 15.4 14.4 11.7 8.2 10.7 16.7 7.2 6.9 37.0 16.5 18.2 16.2 25.9 9.8 5.2 17.3 15.8 6.2 9.6 5.5 8.4 7.5 17.9 17.9 9.0 2.5 11.1 8.4 37.6 12.9 10.6 8.7 15.9 9.8 12.9 30.2 16.8 3.8 7.2 24.8 7.3 13.9 11.7 17.2 47.2 57.8 14.6 32.8 52.2 33.9 24.0 67.2 29.8 55.6 45.9 36.3 44.2 20.0 36.1 28.6 67.1 44.4 17.5 39.4 56.7 45.6 30.4 40.4 39.0 42.6 55.9 32.8 39.0 23.1 33.8 76.5 38.4 21.6 35.7 13.7 60.8 21.9 68.4 66.3 26.9 60.6 16.8 75.6 38.2 23.7 22.9 48.3 53.7 31.4 13.8 12.4 26.9 81.2 240.2 21.6 35.2 37.5 21.6 42.8 11.2 93.7 70.5 42.6 48.7 41.4 40.8 38.1 61.2 13.6 18.8 26.6 12.7 23.1 14.2 13.2 13.4 11.7 22.5 10.8 11.7 13.4 9.6 16.1 30.0 9.2 18.6 14.5 16.0 16.5 17.0 28.7 16.5 18.2 17.3 15.8 17.9 15.9 16.8 17.2 24.2 9.6 10.1 5.5 14.8 18.2 21.1 39.1 14.2 7.2 21.7 23.6 62.8 12.8 21.5 16.5 6.2 39.2 19.5 25.8 29.4 41.1 796.4 16.1 24.2 18.7 13.8 15.6 11.3 41.4 41.6 25.2 14.8 17.7 46.9 16.4 11.0 30.3 44.2 1.7 10.1 26.5 32.6 15.0 26.9 1841.1 17.4 26.8 26.6 5.6 25.9 9.9 28.8 5.0 10.1 38.3 31.5 18.0 20.5 39.2 40.3 74.3 13.9 11.5 6.6 15.5 36.2 12.3 25.4 21.3 19.9 24.8 14.0 33.1 24.1 20.5 GLT8D2 FLJ31494 ENSG00000120820 "Glycosyltransferase 8 domain containing 2" Q9H1C3 12 103988987-104064183 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 26.3;Early spermatids: 41.2;Fibroblasts: 55.9;Leydig cells: 55.9;Peritubular cells: 51.9;Skeletal myocytes: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 69.3;BJ hTERT+: 89.4;HSkMC: 63.2;hTERT-RPE1: 51.9;RPTEC TERT1: 45.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA012740, HPA026904, HPA070791" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "HPA012740: , HPA026904: AB_1849731, HPA070791: " "unprognostic (4.02e-1)" "prognostic unfavorable (7.37e-4)" "unprognostic (9.53e-2)" "unprognostic (4.56e-2)" "unprognostic (1.92e-2)" "unprognostic (1.71e-1)" "unprognostic (4.34e-3)" "unprognostic (2.57e-1)" "unprognostic (1.25e-1)" "unprognostic (7.55e-2)" "unprognostic (5.03e-2)" "unprognostic (8.87e-2)" "prognostic unfavorable (1.58e-6)" "prognostic unfavorable (7.92e-4)" "unprognostic (7.15e-2)" "unprognostic (7.70e-3)" "unprognostic (7.03e-3)" 16.9 10.9 4.2 5.2 4.9 1.5 19.5 2.6 5.1 29.6 11.2 17.6 5.8 27.4 21.6 7.5 22.3 35.8 15.4 4.8 3.7 4.3 2.7 10.2 6.0 2.9 3.1 41.6 4.5 6.6 9.6 9.4 3.1 13.3 11.4 1.0 7.7 16.0 3.2 4.1 7.7 21.8 2.8 1.6 8.4 6.8 3.7 2.2 26.3 11.5 5.8 20.8 18.9 4.4 0.3 0.6 0.7 22.2 28.3 69.3 0.5 32.0 89.4 8.3 10.5 0.4 0.2 0.9 1.8 37.5 0.4 0.1 0.4 11.9 7.0 1.6 10.0 0.6 11.2 0.2 12.7 0.9 0.5 63.2 0.7 10.0 13.8 51.9 4.4 0.6 0.4 1.3 36.5 0.3 0.8 0.5 2.7 0.1 6.7 1.0 33.6 0.2 45.5 0.4 1.3 1.7 33.5 0.8 0.4 2.4 6.0 0.5 0.7 13.2 6.2 1.3 1.9 3.9 0.8 0.3 1.0 0.7 1.1 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.2 4.9 2.6 5.1 4.8 3.7 2.9 3.1 3.1 2.8 3.7 4.4 8.0 0.0 4.6 2.9 0.3 2.8 4.2 2.4 0.0 0.8 1.0 26.3 3.9 1.5 0.1 0.0 2.1 4.1 0.4 0.0 0.0 0.1 41.2 0.6 8.3 7.5 1.8 0.0 10.2 0.0 0.8 55.9 1.1 0.4 0.0 0.1 20.7 0.3 0.6 0.0 10.5 1.3 0.0 0.6 2.8 11.5 55.9 0.4 3.6 4.7 0.6 0.5 0.0 1.0 2.6 0.3 0.0 51.9 1.2 1.4 0.0 0.0 0.1 0.5 6.6 25.2 18.0 1.1 1.1 0.2 2.4 1.4 0.6 10.7 0.0 0.1 GLTPD2 ENSG00000182327 "Glycolipid transfer protein domain containing 2" A6NH11 17 4788964-4790589 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 73.8" "Group enriched" "Detected in some" 5 "Hepatocytes: 83.7;Proximal tubular cells: 135.8" "Cancer enriched" "Detected in many" 5 "liver cancer: 25.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BEWO: 3.4;CACO-2: 9.2;Hep G2: 13.7;MCF7: 4.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA058295, HPA065267" Uncertain Approved Vesicles "Secreted - unknown location" NA NA 150000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA058295: AB_2683671, HPA065267: AB_2685451" "unprognostic (4.00e-1)" "unprognostic (1.93e-1)" "unprognostic (1.95e-3)" "unprognostic (1.70e-1)" "unprognostic (3.03e-2)" "unprognostic (1.79e-4)" "unprognostic (1.40e-1)" "unprognostic (1.45e-2)" "unprognostic (4.16e-3)" "unprognostic (2.33e-2)" "unprognostic (5.62e-4)" "unprognostic (7.80e-2)" "unprognostic (2.62e-1)" "unprognostic (4.25e-1)" "unprognostic (4.79e-1)" "unprognostic (1.71e-4)" "unprognostic (7.59e-3)" 0.5 0.5 1.3 0.5 1.1 1.5 0.3 2.3 2.7 0.4 0.0 0.5 10.1 0.5 0.0 0.8 0.4 0.3 0.2 1.0 2.1 12.0 73.8 0.4 0.1 3.1 2.8 0.3 0.7 0.2 0.8 0.1 2.0 0.4 0.0 0.3 1.0 0.0 1.3 1.7 6.2 0.0 0.4 1.1 1.1 0.1 1.5 0.0 0.2 0.0 0.0 0.5 0.5 1.4 0.5 1.8 0.1 1.5 0.0 0.0 3.4 0.4 0.0 0.0 0.0 9.2 0.6 0.8 0.9 0.0 0.3 1.7 0.0 0.0 0.0 1.7 1.2 0.1 0.7 13.7 0.1 0.2 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.5 0.4 0.0 4.1 0.1 0.1 0.2 0.6 0.7 0.7 0.5 0.2 0.0 0.7 1.1 0.7 1.6 0.3 0.4 0.0 1.0 0.1 1.7 0.5 0.7 0.4 0.3 0.1 0.5 0.1 0.2 0.5 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.3 1.1 2.3 2.7 1.0 2.1 3.1 2.8 2.0 0.4 1.5 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.1 0.3 0.2 1.5 0.5 0.0 0.0 0.0 0.1 0.4 17.6 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.6 0.2 0.0 0.2 0.0 0.0 2.2 83.7 0.1 0.0 0.2 0.6 0.0 1.3 0.4 0.2 0.6 1.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 1.2 0.0 0.6 0.3 21.1 135.8 0.3 0.0 0.0 0.0 0.0 0.6 0.9 0.0 0.1 0.3 0.3 0.1 0.3 0.4 GM2A SAP-3 ENSG00000196743 "GM2 ganglioside activator" P17900 5 151212150-151270440 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Disease variant, Gangliosidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 224.7;Hofbauer cells: 100.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "B-cells: 30.9;dendritic cells: 39.6;monocytes: 40.4" "Cell line enhanced" "Detected in all" "BEWO: 207.1;HBEC3-KT: 291.8;hTCEpi: 287.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008063 Enhanced Approved Vesicles,Cytosol "Intracellular and membrane" NA NA 19000000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Vesicles, Cytosol" "HPA008063: AB_1849842" "unprognostic (4.33e-2)" "unprognostic (8.97e-3)" "unprognostic (2.27e-1)" "unprognostic (3.01e-1)" "unprognostic (1.10e-1)" "unprognostic (2.70e-1)" "prognostic unfavorable (1.77e-5)" "unprognostic (1.22e-1)" "unprognostic (1.72e-2)" "unprognostic (1.31e-2)" "unprognostic (1.50e-2)" "unprognostic (5.33e-3)" "unprognostic (9.81e-2)" "unprognostic (4.24e-2)" "unprognostic (4.42e-2)" "unprognostic (3.02e-2)" "unprognostic (1.65e-1)" 17.4 20.5 29.3 30.0 39.7 20.6 28.0 38.9 31.1 30.8 17.9 19.7 15.8 15.1 30.8 56.2 15.4 23.4 26.2 27.1 34.3 11.4 24.8 39.0 61.4 42.6 37.9 21.3 14.9 28.3 6.6 57.9 44.3 21.1 26.3 11.7 17.0 17.9 7.2 81.8 16.3 20.0 39.0 36.0 15.8 11.6 36.2 72.3 13.0 10.5 77.9 40.3 49.5 46.7 22.3 14.8 15.1 71.7 98.0 48.2 207.1 35.0 75.1 19.0 25.6 30.3 26.1 71.9 35.1 26.9 51.1 60.0 16.7 291.8 27.2 41.4 10.5 11.7 16.8 37.9 23.7 19.1 117.1 65.4 287.0 24.4 16.4 26.0 27.6 85.1 11.4 30.7 30.1 9.6 38.4 18.0 10.2 11.4 32.3 17.7 7.1 46.3 18.4 43.3 3.9 13.4 29.1 133.0 58.3 52.0 30.7 22.5 24.6 46.0 17.6 38.3 10.6 75.2 96.8 187.0 53.1 30.1 19.4 7.6 40.4 2.4 3.7 13.6 2.7 30.9 4.3 3.9 39.6 29.8 6.1 4.8 8.7 4.4 3.4 28.0 5.4 18.6 29.3 39.7 38.9 31.1 27.1 34.3 42.6 37.9 44.3 39.0 36.2 46.7 5.8 16.0 23.0 5.5 25.0 14.9 18.5 63.2 26.7 5.8 5.4 15.5 30.9 0.0 29.7 18.4 2.1 53.6 8.3 4.4 1.9 7.2 0.5 5.7 6.8 7.3 3.6 5.0 2.2 8.1 224.7 10.2 10.7 7.7 69.6 16.3 8.6 24.2 100.8 6.7 2.7 5.4 10.2 55.7 32.5 1.6 8.1 67.8 8.8 2.8 52.5 8.0 7.2 3.5 9.5 6.0 4.7 13.9 28.8 6.7 6.2 5.4 19.9 3.7 0.0 7.9 6.9 1.8 4.2 45.6 23.9 52.5 5.6 6.4 6.7 36.5 GNAZ ENSG00000128266 "G protein subunit alpha z" P19086 22 23070519-23125032 "Predicted intracellular proteins" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.2" "Cell type enhanced" "Detected in many" "Adipocytes: 32.1;Horizontal cells: 124.5;Rod photoreceptor cells: 37.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 18.3;SCLC-21H: 39.0;SH-SY5Y: 24.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003011 Enhanced Approved Vesicles NA NA 180000 "Cluster 14: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA003011: AB_1078918" "unprognostic (7.61e-2)" "unprognostic (1.63e-2)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.85e-4)" "unprognostic (1.01e-1)" "unprognostic (1.35e-1)" "unprognostic (1.51e-3)" "unprognostic (3.45e-2)" "unprognostic (1.30e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-3)" "unprognostic (1.68e-2)" "unprognostic (9.69e-2)" "unprognostic (2.29e-1)" "unprognostic (6.63e-2)" "unprognostic (2.82e-1)" "unprognostic (1.30e-1)" 9.2 6.6 30.7 2.8 35.9 1.6 8.4 27.4 36.2 5.4 27.8 14.8 1.7 10.1 2.8 5.0 10.2 11.2 2.4 33.6 24.5 2.0 0.5 1.4 1.8 29.6 30.7 8.9 1.6 7.5 24.1 0.3 32.0 8.5 1.6 33.0 1.8 17.2 1.4 1.4 3.2 11.9 27.0 4.7 11.5 4.3 29.0 0.5 1.5 2.1 1.2 8.0 3.6 35.7 0.1 2.0 6.8 14.3 0.0 0.0 0.4 9.2 18.3 8.9 6.0 0.1 0.1 17.7 0.6 0.8 12.2 0.3 8.4 0.3 6.4 2.2 7.0 1.1 10.2 13.1 0.6 0.0 1.4 0.0 0.3 0.2 0.5 2.2 0.2 1.0 0.2 5.4 0.2 6.4 0.1 0.1 4.1 0.5 5.5 0.1 6.8 2.7 0.1 0.1 39.0 24.0 2.0 4.4 1.9 0.8 1.9 0.2 0.0 7.2 8.2 2.0 0.2 6.6 12.0 9.2 3.7 0.6 2.8 0.9 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.2 0.3 0.0 0.6 0.0 0.0 2.0 30.7 35.9 27.4 36.2 33.6 24.5 29.6 30.7 32.0 27.0 29.0 35.7 32.1 3.2 0.0 4.9 0.7 0.3 0.3 0.4 0.0 12.6 0.8 1.7 1.6 7.2 0.7 3.7 8.4 0.0 0.7 0.3 0.0 2.0 1.5 1.6 0.5 5.0 4.8 2.7 11.0 1.6 0.0 1.1 1.5 0.4 0.0 2.1 2.2 0.4 0.1 124.5 11.0 0.3 2.0 0.0 1.7 2.1 4.1 18.6 1.8 1.0 1.2 19.3 1.0 2.0 16.5 0.7 0.0 4.1 0.1 0.3 0.1 0.9 1.3 37.7 0.0 9.0 2.1 2.0 4.2 0.0 0.4 0.0 0.6 0.9 0.2 0.1 GNG2 ENSG00000186469 "G protein subunit gamma 2" P59768 14 51826195-51979342 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 113.4" "Cell type enhanced" "Detected in many" "dendritic cells: 251.8;Early spermatids: 714.4;Late spermatids: 1146.4;NK-cells: 246.1" "Cancer enhanced" "Detected in all" "glioma: 15.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 77.2;fHDF/TERT166: 140.2;MOLT-4: 112.5;SH-SY5Y: 89.2;WM-115: 249.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003534, CAB018380" Uncertain Supported Approved "Vesicles,Plasma membrane" NA NA 170000 "Cluster 46: Basophils - DNA binding" "Cluster 65: Brain - Ion transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" Vesicles "CAB018380: AB_631547, HPA003534: AB_1079004" "unprognostic (6.11e-2)" "unprognostic (5.78e-3)" "unprognostic (2.06e-3)" "unprognostic (6.55e-2)" "unprognostic (1.33e-1)" "unprognostic (4.01e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (5.72e-2)" "unprognostic (1.24e-1)" "prognostic favorable (1.64e-4)" "unprognostic (8.47e-2)" "prognostic unfavorable (3.90e-6)" "unprognostic (9.82e-2)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (3.59e-2)" 51.3 22.0 38.5 41.1 44.8 64.0 21.0 0.8 55.4 11.9 10.9 24.1 15.2 12.2 5.1 14.1 5.8 17.3 13.5 54.1 75.2 7.5 12.7 19.0 47.7 10.6 20.5 14.4 7.3 3.5 14.9 19.5 27.2 10.6 19.6 15.0 8.1 9.0 5.6 7.8 21.2 19.8 13.6 61.7 15.9 113.4 46.4 62.0 5.7 13.1 45.4 22.2 5.3 22.2 0.0 3.1 77.2 48.6 11.6 15.0 1.2 12.9 15.9 6.1 4.9 6.4 0.2 0.2 1.8 140.2 8.9 0.3 10.4 0.0 4.2 36.4 1.2 0.0 0.7 0.0 6.0 7.4 0.3 25.1 0.0 6.2 0.5 32.2 0.0 67.9 0.0 6.5 39.7 0.0 112.5 12.0 41.1 0.0 9.5 39.4 6.1 2.0 6.4 0.0 11.5 89.2 0.3 0.1 34.5 2.7 0.0 0.3 0.0 18.7 3.1 0.3 9.9 0.2 0.0 5.5 15.5 39.2 249.0 379.4 64.0 177.1 162.8 111.9 110.5 38.1 88.9 134.2 65.8 36.2 55.5 98.5 185.2 25.2 177.3 28.0 143.2 158.6 38.5 44.8 0.8 55.4 54.1 75.2 10.6 20.5 27.2 13.6 46.4 22.2 11.6 6.4 7.2 3.3 101.3 11.5 0.4 0.0 2.2 18.7 1.5 1.9 1.0 1.5 0.0 3.7 2.1 0.6 251.8 0.8 1.9 0.2 714.4 0.5 2.7 11.7 175.8 20.4 66.2 0.0 0.6 23.9 11.7 0.8 32.3 0.2 11.0 0.9 51.1 0.0 59.6 2.4 0.0 94.1 60.0 1146.4 9.9 84.0 55.2 24.4 33.3 0.7 246.1 96.0 3.2 0.5 0.1 6.0 62.7 0.2 0.1 0.9 0.0 2.2 39.5 10.2 12.2 11.2 4.6 1.3 6.7 0.7 191.5 2.2 0.5 0.2 GNL1 HSR1 ENSG00000204590 "G protein nucleolar 1 (putative)" P36915 6 30541377-30557174 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 193.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033575, HPA043338, HPA050455" Uncertain Supported Vesicles NA NA 11000 "Cluster 39: Non-specific - mRNA processing" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "CAB033575: AB_2109945, HPA043338: AB_2678437, HPA050455: AB_2681132" "unprognostic (2.76e-2)" "unprognostic (3.68e-2)" "unprognostic (2.21e-1)" "unprognostic (3.53e-2)" "unprognostic (3.30e-2)" "unprognostic (2.75e-1)" "unprognostic (4.22e-2)" "unprognostic (8.33e-2)" "unprognostic (1.03e-1)" "unprognostic (3.84e-2)" "unprognostic (3.95e-3)" "unprognostic (7.32e-2)" "unprognostic (5.67e-3)" "unprognostic (4.42e-2)" "unprognostic (2.10e-1)" "unprognostic (4.15e-1)" "unprognostic (1.78e-1)" 22.6 19.6 3.3 3.5 3.5 2.0 21.7 2.0 4.0 30.5 1.7 19.3 0.6 27.3 3.9 17.0 26.2 2.4 15.2 2.3 4.8 21.2 13.1 27.8 2.3 3.3 3.0 37.5 24.3 7.8 23.8 2.8 3.5 19.9 3.4 4.1 16.6 3.9 15.0 23.3 17.4 4.5 2.7 18.7 20.0 38.0 4.7 5.0 23.3 1.6 4.6 21.1 22.9 5.4 10.5 2.2 5.9 16.9 10.9 12.8 0.4 3.2 6.4 2.6 4.0 15.1 6.5 4.8 6.2 10.4 25.8 6.9 15.4 12.7 4.4 1.8 9.0 7.8 7.9 1.4 0.0 1.3 5.0 11.0 9.9 20.4 6.7 0.0 1.1 18.6 14.2 0.3 6.5 2.4 3.8 0.2 3.4 8.4 1.6 7.3 3.6 5.3 8.7 4.5 5.2 4.9 4.2 3.1 1.6 2.0 3.0 4.9 6.2 10.5 3.0 2.0 3.7 7.9 9.3 9.9 0.1 6.6 13.1 0.2 0.2 0.2 0.7 0.2 1.0 0.4 0.8 0.9 0.0 0.3 0.1 0.3 0.2 0.4 0.2 0.1 0.5 0.5 3.3 3.5 2.0 4.0 2.3 4.8 3.3 3.0 3.5 2.7 4.7 5.4 48.2 44.8 41.8 17.3 45.0 59.3 104.0 44.1 56.3 40.6 35.4 40.6 14.3 34.3 28.8 25.8 41.7 72.6 36.3 22.6 23.5 38.4 113.1 30.0 40.2 50.8 46.0 13.3 26.2 35.3 65.5 46.4 27.5 47.5 31.7 40.9 50.7 16.9 28.5 16.8 27.0 25.8 26.4 19.8 32.5 193.5 36.4 24.6 28.4 9.4 14.8 30.9 18.6 11.1 10.8 29.9 22.1 32.0 42.6 56.2 32.4 30.3 20.7 34.6 39.5 47.9 58.1 108.4 51.8 36.1 40.6 160.1 46.0 40.9 27.0 66.7 GNPDA1 "GNPDA, GNPI, GPI, HLN, KIAA0060" ENSG00000113552 "Glucosamine-6-phosphate deaminase 1" P46926 5 141991749-142013041 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 127.2;Proximal tubular cells: 102.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "GAMG: 382.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000499, HPA046891" Uncertain Approved "Golgi apparatus,Vesicles" NA NA 930000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Golgi apparatus" "HPA000499: AB_1079005, HPA046891: AB_2679857" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "unprognostic (6.79e-2)" "unprognostic (1.04e-1)" "unprognostic (9.51e-2)" "unprognostic (8.89e-3)" "prognostic unfavorable (2.60e-6)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (3.45e-1)" "unprognostic (3.09e-1)" "unprognostic (1.58e-1)" "unprognostic (2.61e-1)" "unprognostic (1.16e-1)" "unprognostic (5.82e-2)" "unprognostic (9.66e-2)" "unprognostic (2.05e-3)" 18.8 38.4 26.9 17.3 28.8 8.1 20.9 26.2 35.2 26.7 27.7 19.7 29.5 28.7 51.9 13.6 18.4 22.3 17.3 28.1 30.8 76.4 16.6 17.6 22.7 27.0 27.7 31.8 11.3 27.9 20.5 22.2 29.3 22.2 21.9 17.7 14.6 28.3 26.4 14.8 22.5 29.2 27.0 30.9 14.5 18.8 29.7 24.9 27.8 25.7 19.8 33.3 17.1 30.7 42.6 61.0 23.2 115.8 77.1 51.9 54.6 32.6 78.7 84.7 95.8 91.3 49.2 0.2 72.9 23.6 382.3 44.0 109.9 98.0 74.8 32.9 46.5 31.3 33.1 65.5 137.2 86.4 39.2 63.5 56.9 54.5 144.8 63.2 91.6 80.6 37.3 110.1 93.0 27.2 66.8 9.8 88.0 62.8 121.4 25.5 76.3 94.3 81.8 114.8 20.6 54.0 65.0 67.8 127.9 67.5 54.6 26.5 43.3 50.9 33.3 76.9 47.5 61.2 126.9 47.1 74.2 29.3 45.0 0.3 48.6 7.1 37.2 59.1 77.9 19.4 30.0 34.2 51.7 11.1 35.3 38.8 12.7 15.8 56.3 29.6 27.6 40.2 26.9 28.8 26.2 35.2 28.1 30.8 27.0 27.7 29.3 27.0 29.7 30.7 10.5 9.6 14.9 10.7 8.2 6.0 40.8 20.9 21.1 11.6 12.6 17.8 12.6 12.8 20.1 18.4 8.4 26.7 11.1 6.9 35.2 29.3 1.1 5.8 19.8 14.6 15.0 9.9 11.5 14.2 48.6 22.8 7.7 9.6 12.0 30.8 15.4 7.4 127.2 6.7 12.7 6.2 12.2 60.2 10.7 3.6 19.9 48.5 14.2 12.2 23.5 40.5 15.5 7.1 11.5 21.6 7.1 26.7 7.8 32.9 19.4 102.3 8.0 7.9 0.0 10.4 11.7 10.4 17.0 17.6 7.4 29.7 16.6 64.8 9.1 34.7 GNPDA2 SB52 ENSG00000163281 "Glucosamine-6-phosphate deaminase 2" Q8TDQ7 4 44682200-44726588 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000499, HPA046891" Uncertain Approved "Golgi apparatus,Vesicles" NA NA 820000 "Cluster 44: Non-specific - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" Vesicles "Golgi apparatus" "HPA000499: AB_1079005, HPA046891: AB_2679857" "unprognostic (1.91e-1)" "unprognostic (2.76e-1)" "unprognostic (1.04e-1)" "unprognostic (1.16e-1)" "unprognostic (1.90e-2)" "unprognostic (3.29e-1)" "unprognostic (1.55e-3)" "unprognostic (1.02e-1)" "unprognostic (1.33e-1)" "unprognostic (9.57e-2)" "unprognostic (9.75e-3)" "unprognostic (1.03e-1)" "unprognostic (1.28e-3)" "unprognostic (4.18e-2)" "unprognostic (6.86e-2)" "unprognostic (1.63e-2)" "unprognostic (3.13e-2)" 13.1 12.6 9.6 9.8 10.8 8.4 14.5 21.9 13.3 13.9 7.5 12.3 7.9 16.6 14.0 10.1 12.6 10.5 17.5 10.8 9.9 13.8 4.0 10.0 12.6 9.5 9.8 22.6 8.2 13.0 12.8 6.7 9.9 14.7 8.2 18.5 9.2 15.2 11.3 9.7 8.5 16.5 10.4 11.8 9.1 11.6 9.8 13.2 18.1 10.1 10.5 12.0 10.0 12.5 15.7 10.9 11.4 9.7 17.8 24.7 3.9 27.1 30.3 17.9 16.7 5.6 19.1 13.6 15.5 23.4 29.8 5.3 10.6 26.3 19.7 18.4 11.9 19.3 16.6 9.2 18.8 20.8 17.7 28.5 18.1 17.9 13.1 22.6 26.5 18.1 12.2 17.9 33.6 0.7 25.2 11.6 5.5 10.4 19.5 16.3 24.3 8.0 17.3 9.5 19.5 15.8 12.1 7.0 27.2 5.4 14.9 12.1 25.9 23.7 22.6 38.5 31.6 23.0 38.7 19.7 38.6 14.3 21.3 9.3 2.4 5.0 9.7 3.6 11.2 12.2 9.0 9.3 3.7 10.5 11.2 10.8 1.1 9.8 4.9 2.8 10.7 4.7 9.6 10.8 21.9 13.3 10.8 9.9 9.5 9.8 9.9 10.4 9.8 12.5 18.4 9.6 4.6 17.0 19.8 12.5 8.9 18.6 8.0 15.6 9.2 8.1 14.1 2.8 9.4 14.7 8.4 1.2 15.7 3.0 15.6 13.3 30.3 7.9 21.9 14.4 6.7 6.5 29.1 15.1 1.1 22.0 7.1 8.5 15.8 8.5 11.4 1.6 4.8 13.5 29.2 4.4 18.3 3.7 8.7 5.0 16.1 4.2 8.8 8.4 4.3 19.8 13.4 31.2 20.4 14.2 2.9 23.7 6.3 5.2 2.9 13.2 8.0 18.2 13.1 14.3 20.0 34.4 29.9 5.7 10.7 0.5 13.7 20.0 4.4 5.2 GOLGA6A "GLP, GOLGA6" ENSG00000159289 "Golgin A6 family member A" Q9NYA3 15 74069857-74082550 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "liver: 4.1;testis: 15.1" "Cell type enriched" "Detected in some" 8 "Early spermatids: 47.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/70: 1.3" "HPA044978, HPA050087, HPA072134" Supported Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "Nucleoplasm, Centrosome" "HPA044978: AB_2679165, HPA050087: AB_2681010, HPA072134: " "unprognostic (1.68e-1)" "unprognostic (2.09e-2)" "unprognostic (9.50e-2)" "unprognostic (9.67e-2)" "unprognostic (6.70e-2)" 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 4.1 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 15.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GOLGA6B ENSG00000215186 "Golgin A6 family member B" A6NDN3 15 72654738-72666394 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 19 "liver: 3.5;testis: 7.2" "Group enriched" "Detected in some" 4 "Astrocytes: 3.9;Early spermatids: 8.6;Excitatory neurons: 2.7;Inhibitory neurons: 2.7;Oligodendrocytes: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044978, HPA050087, HPA072134" Supported Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "Nucleoplasm, Centrosome" "HPA044978: AB_2679165, HPA050087: AB_2681010, HPA072134: " "unprognostic (5.47e-3)" "unprognostic (1.88e-2)" "unprognostic (2.07e-1)" "unprognostic (2.01e-1)" "unprognostic (2.03e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GOLGA6C ENSG00000167195 "Golgin A6 family member C" A6NDK9 15 75258599-75270199 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 27 "testis: 9.9" "Cell type enriched" "Detected in some" 6 "Early spermatids: 9.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044978, HPA050087, HPA072134" Supported Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "Nucleoplasm, Centrosome" "HPA044978: AB_2679165, HPA050087: AB_2681010, HPA072134: " "unprognostic (6.53e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 GOLGA6D ENSG00000140478 "Golgin A6 family member D" P0CG33 15 75282835-75295807 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 12.1" "Cell type enriched" "Detected in some" 4 "Early spermatids: 12.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044978, HPA050087, HPA072134" Supported Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "Nucleoplasm, Centrosome" "HPA044978: AB_2679165, HPA050087: AB_2681010, HPA072134: " "unprognostic (7.95e-3)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 12.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 GOLPH3 "GOPP1, GPP34, MIDAS, Vps74" ENSG00000113384 "Golgi phosphoprotein 3" Q9H4A6 5 32124716-32174319 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044564, HPA055841" Approved Supported "Golgi apparatus,Vesicles" NA NA 23000 "Cluster 26: Non-specific - Mitochondria" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 28: BEWO - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus, Vesicles" "HPA044564: AB_10795169, HPA055841: AB_2682940" "unprognostic (1.64e-2)" "unprognostic (1.66e-1)" "unprognostic (9.27e-2)" "unprognostic (1.01e-1)" "unprognostic (2.28e-1)" "unprognostic (9.34e-2)" "unprognostic (1.89e-2)" "unprognostic (8.19e-2)" "unprognostic (2.95e-2)" "unprognostic (7.48e-2)" "unprognostic (2.02e-1)" "unprognostic (1.96e-1)" "unprognostic (1.58e-1)" "unprognostic (1.15e-1)" "unprognostic (8.56e-2)" "unprognostic (1.11e-1)" "unprognostic (1.52e-2)" 50.1 38.3 28.5 41.9 29.2 20.8 50.0 29.8 34.5 56.2 32.9 76.6 46.3 41.6 58.7 43.1 41.0 77.7 38.4 26.5 29.6 61.5 110.1 50.7 49.2 30.2 29.5 51.5 62.6 54.9 29.8 68.4 29.9 75.3 60.2 19.8 64.8 50.4 37.3 32.8 49.3 52.3 29.1 39.5 52.9 27.0 29.7 43.9 48.0 57.0 52.4 60.5 41.3 32.3 57.7 37.9 59.9 65.5 111.3 106.1 171.6 77.8 103.3 71.5 67.7 51.9 101.3 51.7 75.0 105.7 69.3 52.8 75.1 54.9 89.7 67.7 44.9 56.9 119.9 99.4 89.4 88.8 64.0 81.3 77.1 70.3 80.1 65.8 57.9 33.6 60.5 121.8 80.4 58.0 57.1 115.3 51.8 78.0 38.5 52.8 86.4 53.8 89.9 72.1 45.6 51.0 180.8 186.9 79.4 75.6 76.4 97.1 56.5 62.7 58.5 49.7 55.6 136.1 179.3 62.5 56.3 125.8 76.4 6.8 8.0 19.2 7.8 10.6 6.8 11.5 8.4 10.1 8.9 16.0 9.9 7.2 7.9 8.5 10.5 6.9 13.2 4.2 28.5 29.2 29.8 34.5 26.5 29.6 30.2 29.5 29.9 29.1 29.7 32.3 33.9 60.9 49.2 26.8 53.3 70.0 44.5 30.0 51.2 13.5 59.6 30.7 31.7 88.6 42.8 44.1 10.4 67.3 52.0 72.6 52.8 58.0 5.2 46.3 35.8 46.2 52.0 50.5 47.9 44.1 111.6 51.7 57.6 71.3 14.5 16.8 59.3 153.6 54.4 13.5 45.8 86.3 40.7 63.7 56.2 16.1 50.7 49.1 44.4 43.1 48.7 20.2 36.0 53.8 60.1 49.7 35.1 57.2 120.0 83.9 59.8 59.8 49.1 10.0 39.5 30.8 52.1 15.4 25.1 68.2 73.6 110.0 45.6 50.4 50.2 80.7 GOLT1B "CGI-141, GOT1, YMR292W" ENSG00000111711 "Golgi transport 1B" Q9Y3E0 12 21501781-21518408 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055909, HPA066383" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 5: NTERA-2 - Transcription" "Cluster 55: Plasma cells - Humoral immune response" Vesicles Nucleoplasm "HPA055909: AB_2682967, HPA066383: AB_2685667" "unprognostic (1.22e-2)" "unprognostic (3.07e-3)" "unprognostic (1.84e-1)" "unprognostic (3.65e-1)" "unprognostic (3.45e-1)" "unprognostic (5.37e-3)" "prognostic unfavorable (1.99e-8)" "unprognostic (2.24e-2)" "unprognostic (1.60e-1)" "unprognostic (1.76e-1)" "prognostic unfavorable (2.32e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (4.83e-10)" "unprognostic (3.13e-1)" "unprognostic (2.14e-1)" "unprognostic (6.78e-2)" "unprognostic (1.04e-1)" 17.5 22.1 12.7 16.9 14.1 25.8 18.5 13.4 18.9 18.0 12.7 13.4 10.6 14.6 15.6 13.6 12.5 13.9 14.8 13.9 15.1 15.5 18.8 17.6 15.0 13.2 14.6 10.9 21.6 11.9 19.0 29.0 13.8 16.1 14.8 14.1 16.1 13.2 15.5 12.9 11.3 17.7 13.9 12.4 14.2 10.6 14.7 11.2 15.9 11.8 14.1 17.8 12.2 16.3 31.2 30.0 28.5 36.5 56.5 83.2 46.1 126.5 48.2 40.4 63.3 45.4 48.1 19.4 29.8 66.6 71.0 30.1 23.4 27.2 69.5 29.4 22.8 29.7 19.6 32.8 61.0 37.0 36.8 44.2 50.1 44.9 85.6 67.7 35.8 24.4 18.6 21.1 59.2 30.7 17.3 62.1 75.7 27.8 23.5 14.0 65.0 39.4 32.2 18.7 7.2 23.1 49.0 20.6 70.4 90.2 28.2 39.4 40.6 46.5 49.5 57.1 67.2 20.3 45.9 51.8 63.6 35.5 64.2 48.0 26.6 20.8 22.1 31.4 26.6 22.7 25.8 24.4 27.0 25.9 23.3 23.8 7.2 21.6 29.4 29.4 28.0 27.6 12.7 14.1 13.4 18.9 13.9 15.1 13.2 14.6 13.8 13.9 14.7 16.3 23.4 9.6 15.6 15.0 38.9 46.7 23.4 42.7 27.3 27.6 20.4 11.2 18.9 22.8 36.8 16.5 10.4 29.0 34.9 13.8 27.4 31.6 3.4 10.9 26.3 28.7 13.1 22.9 70.4 33.4 72.4 45.7 15.3 21.7 21.5 10.3 16.8 23.2 41.0 18.5 49.3 31.7 38.7 23.6 65.1 5.2 17.4 35.4 53.4 14.0 26.0 17.5 18.6 25.1 25.4 38.6 15.4 19.9 75.8 49.0 8.7 21.7 18.2 7.7 13.1 24.6 39.3 23.7 32.4 22.8 63.9 64.0 39.1 9.6 14.6 44.9 GPBP1 DKFZp761C169 ENSG00000062194 "GC-rich promoter binding protein 1" Q86WP2 5 57173948-57264679 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 622.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037773 Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Cytosol" "Plasma membrane" "HPA037773: AB_10671721" "unprognostic (1.53e-1)" "unprognostic (2.23e-2)" "unprognostic (1.57e-1)" "unprognostic (3.49e-1)" "unprognostic (8.30e-2)" "unprognostic (9.68e-3)" "unprognostic (1.24e-2)" "unprognostic (3.19e-2)" "unprognostic (6.85e-3)" "unprognostic (3.70e-1)" "unprognostic (5.93e-2)" "unprognostic (5.48e-2)" "unprognostic (3.75e-2)" "unprognostic (1.65e-1)" "unprognostic (4.89e-2)" "unprognostic (2.57e-1)" "prognostic favorable (4.15e-5)" 39.2 48.6 67.6 37.8 72.0 66.0 55.7 87.7 87.8 46.5 63.6 38.9 31.2 42.6 48.0 36.9 47.0 36.6 39.8 66.0 67.8 48.0 44.0 43.5 57.8 66.2 68.0 65.1 35.7 50.1 41.7 43.3 66.8 42.1 36.9 83.7 42.6 36.5 59.0 38.2 40.3 32.7 68.5 48.1 37.6 75.2 67.3 69.0 51.5 56.5 53.0 43.9 38.0 85.4 56.4 45.3 83.7 70.1 53.8 51.6 75.9 42.9 72.4 68.6 88.4 73.0 63.2 74.2 48.0 44.0 84.9 37.5 71.9 48.6 86.8 41.7 48.1 61.9 49.6 61.5 62.9 45.2 60.8 43.6 74.8 56.1 78.1 65.8 56.7 59.5 62.3 117.6 56.4 72.3 70.3 78.6 51.2 28.2 31.3 75.4 68.5 72.7 53.7 58.7 72.7 56.0 62.1 53.4 69.6 54.3 104.9 75.8 37.3 25.0 50.2 35.1 62.0 90.0 79.6 81.6 40.7 66.7 46.9 93.8 38.2 76.4 59.6 41.0 76.3 71.5 72.1 72.6 43.7 61.9 78.5 73.8 73.2 79.5 45.5 29.8 84.9 68.8 67.6 72.0 87.7 87.8 66.0 67.8 66.2 68.0 66.8 68.5 67.3 85.4 132.9 60.9 88.3 129.3 272.2 227.5 241.1 102.6 206.1 139.8 146.1 87.9 89.0 65.8 121.9 84.6 148.0 99.0 246.9 149.6 99.7 76.5 249.9 246.6 134.0 123.1 107.7 82.7 106.4 55.9 74.3 143.2 115.2 267.8 142.8 119.0 68.2 47.0 56.2 134.6 96.4 103.3 118.0 70.3 622.0 102.4 133.9 162.8 188.5 112.4 160.7 95.7 178.2 168.9 221.6 70.5 176.3 91.4 261.6 246.5 87.9 72.6 154.6 199.0 52.6 129.7 139.9 379.3 279.6 195.6 237.7 161.7 285.2 107.0 102.0 304.1 GPC6 ENSG00000183098 "Glypican 6" Q9Y625 13 93226807-94408020 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 163.2;Excitatory neurons: 333.6;Inhibitory neurons: 496.1;Oligodendrocyte precursor cells: 691.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 62.5;HSkMC: 70.8;hTERT-RPE1: 64.3;SuSa: 39.5;U-87 MG: 52.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA017671 Approved Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 420000 "Cluster 48: NK-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus, Vesicles" "HPA017671: AB_1849833" "unprognostic (5.24e-2)" "unprognostic (4.65e-2)" "unprognostic (2.28e-1)" "unprognostic (9.76e-2)" "unprognostic (1.72e-1)" "unprognostic (5.50e-2)" "unprognostic (1.28e-1)" "unprognostic (4.79e-3)" "unprognostic (5.25e-2)" "unprognostic (2.66e-2)" "unprognostic (2.33e-2)" "unprognostic (3.71e-2)" "unprognostic (2.53e-3)" "unprognostic (6.21e-3)" "unprognostic (7.42e-2)" "unprognostic (3.36e-1)" "unprognostic (3.35e-3)" 9.1 2.2 0.8 8.9 1.9 0.1 2.2 1.7 1.5 3.6 1.1 6.3 2.3 2.4 2.4 5.2 4.1 17.0 6.2 1.3 3.1 7.7 17.7 3.5 0.4 1.7 2.4 7.3 1.6 1.8 2.9 1.3 2.3 6.2 6.5 5.6 3.1 15.1 0.6 1.1 4.3 7.8 2.0 2.2 5.4 2.0 1.9 1.7 1.7 1.9 0.9 11.6 2.4 2.1 0.0 4.7 10.2 4.5 62.5 19.5 0.0 7.2 0.0 4.9 6.4 0.0 0.0 0.2 0.0 16.0 0.0 0.0 5.7 1.2 9.1 0.0 4.1 0.0 0.1 20.2 37.8 0.1 0.1 70.8 0.5 11.7 8.1 64.3 0.0 0.0 0.0 0.1 6.9 0.0 0.0 0.1 6.4 0.0 3.4 0.0 1.6 0.1 5.5 0.0 4.1 16.8 0.0 1.9 0.0 39.5 14.0 0.0 0.0 26.9 22.6 25.4 12.3 15.9 0.1 0.0 52.8 0.0 27.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 1.9 1.7 1.5 1.3 3.1 1.7 2.4 2.3 2.0 1.9 2.1 0.6 0.0 0.5 163.2 0.0 0.6 0.5 0.5 0.6 50.3 0.6 1.9 1.7 4.3 0.7 7.3 10.4 0.2 0.0 0.1 0.0 0.3 6.7 1.6 25.9 1.1 0.0 0.0 333.6 0.0 0.1 31.2 0.0 3.1 0.0 36.0 5.7 41.2 0.5 0.0 496.1 0.1 2.0 1.3 1.0 5.0 4.7 0.5 1.8 31.9 0.0 2.7 0.0 691.6 13.2 0.1 0.0 1.9 0.1 1.6 0.0 14.5 0.0 115.0 0.0 34.4 20.9 4.2 2.7 0.5 0.4 0.1 0.7 11.9 0.1 0.2 GPER1 "CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPER, GPR30, LERGU, LERGU2, LyGPR" ENSG00000164850 "G protein-coupled estrogen receptor 1" Q99527 7 1082208-1093815 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Cell cycle, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 45.3" "Cell type enhanced" "Detected in many" "Adipocytes: 9.6;Distal enterocytes: 15.4;Endothelial cells: 11.3;Hepatocytes: 23.5;Kupffer cells: 16.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.9;intermediate monocyte: 2.8;myeloid DC: 5.8" "Group enriched" "Detected in many" 19 "dendritic cells: 5.8;monocytes: 2.9" "Cell line enhanced" "Detected in many" "AN3-CA: 11.5;Daudi: 12.1;fHDF/TERT166: 8.6;Hep G2: 22.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016718, HPA027052" Approved Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Nucleoli "Nucleoplasm, Vesicles, Cytosol" "HPA016718: , HPA027052: AB_10612112" "unprognostic (4.74e-2)" "unprognostic (1.32e-1)" "unprognostic (3.09e-2)" "prognostic favorable (1.17e-4)" "unprognostic (2.17e-1)" "unprognostic (6.17e-2)" "unprognostic (3.45e-1)" "unprognostic (6.38e-2)" "unprognostic (2.40e-1)" "unprognostic (1.23e-1)" "unprognostic (1.42e-2)" "unprognostic (2.49e-1)" "unprognostic (2.37e-2)" "unprognostic (1.79e-2)" "unprognostic (1.58e-1)" "unprognostic (7.26e-2)" "unprognostic (7.78e-2)" 10.6 12.6 12.7 1.5 11.7 0.2 8.4 9.0 15.9 5.4 8.1 10.8 0.6 5.8 0.3 2.2 4.3 1.2 7.1 10.0 9.6 9.7 27.9 12.1 1.9 9.9 10.2 2.4 2.1 0.4 6.1 6.3 10.5 7.2 1.4 0.9 2.9 5.0 4.3 2.8 3.6 1.8 8.4 8.5 45.3 1.5 11.6 0.9 9.7 1.3 1.0 6.1 4.7 9.2 1.1 0.4 0.3 11.5 2.7 2.6 1.1 6.7 4.4 2.1 3.7 0.2 0.3 12.1 1.1 8.6 0.1 0.6 0.1 0.0 0.2 2.6 2.1 0.0 1.4 22.8 0.4 0.1 0.7 1.5 0.0 1.3 0.0 1.6 0.6 0.2 0.1 0.1 0.5 0.8 0.0 0.4 2.2 2.4 7.9 1.1 0.0 0.0 0.2 0.0 0.1 4.5 0.0 0.5 2.5 0.8 0.2 0.1 1.6 0.4 2.8 6.9 2.1 0.0 0.0 4.4 3.8 0.2 0.2 0.0 2.9 0.0 0.0 2.8 0.0 0.2 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 1.4 12.7 11.7 9.0 15.9 10.0 9.6 9.9 10.2 10.5 8.4 11.6 9.2 9.6 0.0 0.0 1.0 1.2 0.5 0.0 0.5 1.8 0.0 0.5 0.5 2.8 0.0 0.0 5.5 0.0 0.0 0.0 15.4 0.0 0.1 0.0 4.4 0.1 11.3 1.2 0.0 0.8 3.1 0.6 1.5 0.5 1.0 0.0 0.4 1.1 23.5 0.6 0.0 0.5 2.8 0.0 16.9 2.7 0.7 2.8 2.9 0.0 1.9 0.6 4.4 0.0 0.5 0.1 0.8 7.4 1.2 0.1 0.8 0.2 5.6 0.0 0.4 0.0 0.7 7.2 0.5 2.7 0.1 0.3 0.0 0.0 0.1 2.0 0.1 GPHA2 "A2, GPA2, MGC126572, ZSIG51" ENSG00000149735 "Glycoprotein hormone subunit alpha 2" Q96T91 11 64934471-64935893 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "pancreas: 360.5" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 2.5;Exocrine glandular cells: 17.4;Pancreatic endocrine cells: 2.4;Spermatocytes: 7.7;Spermatogonia: 3.2" "Cancer enriched" "Detected in some" 7 "testis cancer: 15.8" "Region enhanced" "Detected in single" "cerebellum: 3.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "Hep G2: 21.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA067068 Approved Vesicles "Secreted to blood" NA NA "Cluster 25: Pancreas - Digestion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 1: Pancreatic cells - Digestion" Vesicles "HPA067068: " "unprognostic (1.13e-1)" "unprognostic (8.31e-3)" "unprognostic (1.51e-2)" "unprognostic (9.22e-4)" "unprognostic (7.88e-3)" "unprognostic (2.62e-1)" "unprognostic (1.45e-1)" "unprognostic (3.20e-2)" "unprognostic (1.82e-1)" "unprognostic (1.75e-1)" "unprognostic (5.03e-2)" "unprognostic (9.86e-3)" "unprognostic (1.70e-1)" 0.0 0.1 0.3 0.2 0.6 0.1 0.1 3.6 0.6 0.1 0.0 0.1 0.1 0.2 0.2 0.0 0.4 16.9 0.0 0.3 0.3 0.8 0.7 0.3 0.6 0.4 0.3 2.7 360.5 0.0 28.0 0.0 0.6 0.7 0.0 0.1 0.3 0.5 0.0 0.5 0.5 0.0 0.2 0.6 1.1 10.8 0.4 0.1 0.3 0.0 0.5 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 21.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 3.6 0.6 0.3 0.3 0.4 0.3 0.6 0.2 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.3 0.1 2.5 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 17.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.4 0.0 0.5 0.2 0.0 0.0 0.0 0.0 7.7 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 GPHN KIAA1385 ENSG00000171723 Gephyrin Q9NQX3 14 66507407-67181803 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" "Multifunctional enzyme, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 62.4" "Group enriched" "Detected in many" 4 "Astrocytes: 493.0;Excitatory neurons: 686.5;Inhibitory neurons: 866.7;Oligodendrocyte precursor cells: 576.1;Oligodendrocytes: 597.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003116, CAB004419, HPA024694" Enhanced Approved Vesicles,Cytosol NA NA 6900 "Cluster 16: MAIT-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Cytosol "CAB004419: AB_627670, HPA003116: AB_1078963, HPA024694: AB_1849616" "unprognostic (8.37e-2)" "unprognostic (2.53e-2)" "unprognostic (2.42e-1)" "unprognostic (1.20e-1)" "unprognostic (5.14e-2)" "unprognostic (4.89e-3)" "unprognostic (8.29e-2)" "unprognostic (1.41e-2)" "unprognostic (1.42e-1)" "unprognostic (2.23e-1)" "unprognostic (2.49e-2)" "unprognostic (8.54e-2)" "prognostic favorable (5.25e-12)" "unprognostic (9.81e-2)" "unprognostic (2.27e-1)" "unprognostic (7.50e-2)" "prognostic unfavorable (4.61e-5)" 13.8 11.1 35.5 3.5 36.0 2.6 13.4 48.4 54.1 9.7 20.9 11.8 7.4 9.9 11.6 12.2 11.1 6.2 17.1 36.1 37.6 25.3 62.4 9.3 3.8 32.7 35.3 8.9 23.9 11.7 13.6 3.6 32.3 11.3 10.1 23.1 9.4 6.6 24.5 15.2 9.0 6.2 32.4 6.7 14.7 6.2 34.6 5.8 11.9 13.8 4.3 11.4 10.7 39.5 39.9 8.8 13.7 15.9 14.2 17.5 9.5 11.1 5.7 12.7 12.2 2.8 17.9 0.0 1.8 7.7 5.5 13.1 17.0 19.9 18.9 15.0 14.9 15.8 9.4 22.3 7.8 9.1 15.8 13.3 13.8 2.9 16.0 4.8 11.8 13.8 9.3 14.2 7.1 19.2 11.9 22.2 5.0 28.3 17.0 0.0 32.5 13.2 16.7 7.5 25.8 10.3 10.2 31.6 12.4 3.3 18.5 11.5 6.7 14.1 24.8 11.3 13.0 22.8 9.1 0.3 10.5 0.8 11.2 0.0 0.7 0.3 2.0 1.2 3.2 1.2 2.5 1.7 1.1 1.9 1.7 1.6 0.0 1.3 1.0 1.5 3.0 0.7 35.5 36.0 48.4 54.1 36.1 37.6 32.7 35.3 32.3 32.4 34.6 39.5 11.5 6.4 13.1 493.0 11.8 4.7 9.2 5.8 27.9 34.3 12.4 6.7 12.7 8.6 10.8 1.8 52.1 3.9 3.5 8.6 13.7 4.0 3.8 7.2 13.5 10.7 6.0 7.6 686.5 5.3 2.3 8.7 19.9 13.6 0.0 3.9 15.7 47.6 3.7 43.7 866.7 15.0 8.2 5.8 1.7 5.0 11.1 4.5 1.8 148.0 1.3 8.9 1.0 576.1 597.5 3.1 7.8 5.7 15.1 11.5 7.1 20.1 2.4 34.9 0.0 12.5 11.8 11.8 8.9 26.7 5.8 2.1 7.9 9.0 10.4 6.5 GPR1 ENSG00000183671 "G protein-coupled receptor 1" P46091 2 206175316-206218047 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 12.2" "Group enriched" "Detected in some" 6 "Extravillous trophoblasts: 12.3;Granulosa cells: 42.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 24.7;HHSteC: 133.9;hTCEpi: 61.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA010525 Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "Nucleoplasm, Vesicles" "HPA010525: AB_1078919" "unprognostic (5.32e-2)" "unprognostic (1.20e-1)" "unprognostic (2.82e-1)" "unprognostic (2.25e-2)" "unprognostic (3.27e-5)" "unprognostic (1.36e-1)" "unprognostic (4.00e-3)" "unprognostic (1.49e-2)" "unprognostic (7.89e-2)" "unprognostic (9.94e-2)" "unprognostic (3.42e-3)" "unprognostic (5.65e-2)" "unprognostic (4.29e-4)" "unprognostic (8.48e-4)" "unprognostic (1.21e-1)" "unprognostic (2.68e-2)" "unprognostic (3.06e-3)" 1.5 2.7 0.1 0.2 0.9 0.0 0.7 0.5 0.3 2.6 12.2 0.3 0.1 0.5 0.2 4.5 0.5 1.2 1.6 0.6 0.3 0.4 0.0 0.2 0.8 0.0 0.0 1.3 0.0 0.4 0.2 3.9 0.0 0.2 0.3 0.7 0.9 0.1 0.7 4.8 0.3 1.0 0.0 0.0 0.1 0.9 0.2 0.0 0.3 2.4 0.3 1.0 5.6 0.0 2.2 0.2 1.8 0.0 0.4 7.5 0.6 14.4 24.7 8.8 7.4 0.0 0.0 0.0 0.8 7.3 0.6 0.2 0.7 0.0 2.9 0.0 0.3 0.0 4.2 0.0 133.9 0.0 0.0 5.5 61.8 12.5 20.0 10.2 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.0 6.9 0.5 1.3 0.0 0.0 0.0 0.0 0.0 0.3 6.1 2.9 0.0 0.0 1.6 0.1 0.0 0.3 10.5 4.8 12.5 1.1 0.0 0.0 0.0 3.8 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.5 0.3 0.6 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.5 0.6 0.6 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.8 0.0 12.3 4.5 0.0 0.0 0.0 42.1 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 3.3 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.9 1.2 0.0 0.0 0.8 1.0 0.7 0.5 0.0 0.0 0.4 GPR108 LUSTR2 ENSG00000125734 "G protein-coupled receptor 108" Q9NPR9 19 6729914-6737603 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041924, HPA041951, HPA063863" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus" Vesicles "HPA041924: AB_10804122, HPA041951: AB_10795385, HPA063863: AB_2685135" "unprognostic (2.00e-1)" "unprognostic (1.69e-1)" "unprognostic (1.07e-1)" "prognostic favorable (1.04e-7)" "unprognostic (1.58e-1)" "unprognostic (5.29e-2)" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" "unprognostic (4.23e-2)" "unprognostic (3.01e-2)" "unprognostic (7.89e-2)" "unprognostic (3.57e-2)" "prognostic favorable (1.29e-9)" "unprognostic (8.68e-3)" "unprognostic (2.95e-2)" "unprognostic (4.96e-3)" "unprognostic (4.13e-3)" 29.9 45.2 26.9 18.8 29.3 26.2 32.7 29.7 27.2 36.8 29.9 39.9 32.9 31.6 31.6 39.6 40.1 32.2 22.5 24.2 29.4 42.1 34.4 32.4 23.2 28.9 28.1 34.5 46.7 49.0 23.2 22.2 27.5 34.4 28.1 27.8 57.5 40.2 18.4 31.2 36.6 26.3 27.7 33.3 35.8 25.5 29.1 23.5 41.3 20.5 27.8 31.0 32.9 27.8 33.5 35.9 21.7 42.6 83.0 44.8 24.4 25.6 77.0 34.7 36.7 22.2 37.5 15.8 46.4 52.4 41.6 28.1 24.7 53.3 17.8 64.1 28.4 25.7 37.7 29.6 81.3 16.7 33.7 48.7 100.2 33.5 67.2 45.9 41.3 37.9 26.4 102.7 35.6 23.3 29.5 24.0 15.6 60.2 31.5 23.7 24.7 61.0 72.7 32.6 0.2 23.4 25.9 41.8 38.7 18.4 39.9 40.0 34.4 19.7 12.5 63.2 27.6 66.2 39.3 11.4 68.0 52.9 21.7 79.3 116.1 123.0 82.6 109.7 75.2 48.2 65.2 70.4 84.6 49.9 45.9 52.8 178.4 80.9 130.5 30.0 81.2 132.7 26.9 29.3 29.7 27.2 24.2 29.4 28.9 28.1 27.5 27.7 29.1 27.8 40.8 9.6 14.5 12.7 26.3 26.5 43.7 107.4 21.1 28.3 42.7 33.0 8.0 45.8 59.7 36.8 22.9 58.7 31.1 76.4 37.2 87.7 38.0 30.8 23.6 32.7 21.7 6.9 5.4 110.1 37.2 27.4 39.3 44.1 26.0 15.0 40.7 26.7 57.1 21.9 6.0 57.6 81.4 30.3 46.7 94.9 23.6 42.4 30.2 5.6 50.3 46.0 42.2 7.5 9.6 83.3 83.7 18.4 27.8 29.1 121.2 55.0 39.8 43.0 39.5 22.2 26.4 34.3 19.9 27.2 31.8 58.6 38.9 28.3 47.1 36.1 GPR137C "DKFZp762F0713, TM7SF1L2" ENSG00000180998 "G protein-coupled receptor 137C" Q8N3F9 14 52552836-52637713 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 14.6;epididymis: 8.1;retina: 17.3" "Group enriched" "Detected in many" 5 "Excitatory neurons: 85.5;Inhibitory neurons: 125.4;Oligodendrocyte precursor cells: 101.6;Oligodendrocytes: 137.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 9 "NK-cells: 1.5;T-cells: 1.4" "Cell line enhanced" "Detected in many" "SH-SY5Y: 9.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003640, HPA030763" Uncertain Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA003640: AB_2667025, HPA030763: AB_10602352" "unprognostic (1.39e-1)" "unprognostic (1.45e-1)" "unprognostic (1.23e-1)" "unprognostic (6.84e-2)" "unprognostic (8.50e-3)" "unprognostic (7.34e-3)" "unprognostic (5.95e-3)" "unprognostic (2.32e-2)" "unprognostic (4.41e-2)" "unprognostic (8.42e-4)" "unprognostic (2.20e-2)" "unprognostic (1.04e-1)" "unprognostic (7.88e-2)" "unprognostic (4.08e-1)" "unprognostic (1.38e-2)" "unprognostic (2.83e-1)" "unprognostic (2.60e-1)" 0.5 0.7 5.3 0.2 3.8 0.9 0.5 14.6 7.2 0.6 0.0 0.4 0.7 0.8 8.1 0.4 0.3 1.1 1.0 4.0 5.5 0.4 0.6 0.8 0.4 5.9 5.9 0.7 0.2 0.4 1.5 0.4 5.0 0.7 0.4 17.3 0.2 0.4 0.5 0.2 0.3 0.4 2.4 1.0 0.4 2.9 8.4 0.3 0.6 0.6 0.1 0.4 0.3 7.7 0.8 0.3 6.6 6.4 1.7 0.6 2.7 3.3 2.2 3.2 7.8 0.9 1.4 0.2 1.9 2.2 6.5 1.5 2.5 0.5 4.5 0.4 1.7 0.3 1.5 0.4 0.1 0.1 1.1 0.4 0.0 2.8 0.2 0.6 1.5 1.1 0.9 2.3 4.4 3.8 0.1 0.6 1.1 0.4 4.1 1.2 4.3 0.3 1.0 4.8 7.4 9.1 1.3 0.2 0.1 2.7 4.4 0.0 0.0 6.8 7.6 5.5 2.3 0.4 1.6 0.8 1.5 0.1 1.9 0.0 0.0 0.0 1.0 0.0 1.4 0.0 0.5 1.4 0.0 0.0 0.3 0.5 0.1 1.5 0.1 0.0 0.5 0.2 5.3 3.8 14.6 7.2 4.0 5.5 5.9 5.9 5.0 2.4 8.4 7.7 2.8 0.0 1.3 20.2 0.7 0.6 0.7 0.1 2.2 22.4 1.4 1.4 2.5 1.5 0.1 0.0 2.1 0.3 0.4 0.4 0.0 0.3 2.3 3.4 1.6 3.8 1.2 0.0 85.5 0.2 0.3 1.9 1.1 6.2 0.0 5.6 2.2 0.5 0.5 6.7 125.4 0.7 0.0 2.2 0.8 1.5 0.6 0.9 1.8 21.5 0.2 5.4 1.0 101.6 137.4 0.0 0.0 0.7 1.0 1.8 0.1 0.2 0.1 20.2 0.0 1.1 1.7 6.9 5.1 1.3 0.9 0.1 1.2 1.2 0.1 0.5 GPR17 ENSG00000144230 "G protein-coupled receptor 17" Q13304 2 127645864-127652639 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 19.8;intestine: 23.8" "Cell type enriched" "Detected in some" 58 "Oligodendrocyte precursor cells: 58.3" "Cancer enriched" "Detected in some" 32 "glioma: 16.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "naive B-cell: 1.9" "Lineage enriched" "Detected in single" 19 "B-cells: 1.9" "Cell line enhanced" "Detected in some" "HeLa: 3.1;REH: 4.4;TIME: 4.3;U-2 OS: 1.7;U-2197: 2.0;U-251 MG: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029766 Enhanced Supported Approved Vesicles NA NA "Cluster 24: B-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" Vesicles "HPA029766: AB_10612114" "unprognostic (8.10e-2)" "unprognostic (1.73e-1)" "unprognostic (2.61e-1)" "unprognostic (1.42e-2)" "unprognostic (1.54e-1)" "unprognostic (5.19e-2)" "unprognostic (2.77e-5)" "unprognostic (8.40e-3)" "unprognostic (2.92e-1)" "unprognostic (3.25e-2)" "unprognostic (1.61e-3)" "unprognostic (6.60e-2)" "unprognostic (2.11e-3)" "unprognostic (3.33e-2)" "unprognostic (2.19e-1)" "unprognostic (2.04e-1)" "unprognostic (1.31e-1)" 9.8 1.1 9.1 3.4 6.3 0.1 7.9 4.7 9.7 3.6 3.5 23.8 1.5 14.8 1.4 2.4 5.3 2.1 19.8 6.4 5.5 3.0 2.6 9.3 1.1 7.2 7.5 1.8 2.2 0.0 0.7 1.2 7.2 5.5 0.1 0.1 2.0 0.0 7.5 3.4 6.0 0.0 6.4 7.5 5.8 0.9 7.7 0.1 3.8 0.2 0.0 8.8 5.0 8.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.1 0.3 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 3.1 0.5 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.1 4.4 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 1.2 0.1 0.0 4.3 0.0 1.7 2.0 2.6 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 6.3 4.7 9.7 6.4 5.5 7.2 7.5 7.2 6.4 7.7 8.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 58.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 GPR174 FKSG79 ENSG00000147138 "G protein-coupled receptor 174" Q9BXC1 X 79144688-79175318 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 16.9" "Cell type enhanced" "Detected in some" "B-cells: 6.6;dendritic cells: 30.6;Plasma cells: 4.2;T-cells: 18.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "JURKAT: 42.3;MOLT-4: 75.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041025, HPA058306" Enhanced Supported "Vesicles,Plasma membrane,Centriolar satellite" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" "Vesicles, Centriolar satellite" "HPA041025: AB_10794260, HPA058306: " "unprognostic (6.38e-3)" "unprognostic (9.87e-3)" "unprognostic (4.36e-2)" "unprognostic (1.18e-2)" "unprognostic (1.84e-1)" "unprognostic (8.48e-4)" "unprognostic (7.12e-2)" "unprognostic (1.05e-2)" "unprognostic (1.75e-1)" "unprognostic (2.02e-1)" "unprognostic (2.46e-1)" "unprognostic (1.05e-1)" "unprognostic (6.53e-5)" "unprognostic (2.27e-1)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "unprognostic (1.78e-2)" 0.8 0.4 0.5 6.9 0.3 2.5 0.9 0.6 0.6 0.4 0.3 1.0 2.0 0.5 0.6 0.3 0.3 1.1 0.3 0.4 0.4 0.5 1.0 1.9 15.2 0.7 0.5 0.2 0.1 0.1 0.1 0.2 0.7 0.7 1.6 0.2 1.5 0.1 0.2 0.2 3.6 0.3 0.3 8.1 2.1 0.1 0.4 16.9 0.9 0.1 10.4 1.4 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.3 0.0 1.2 0.0 0.0 75.1 0.1 0.0 0.0 0.0 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.2 0.0 0.0 0.0 6.5 0.0 3.6 3.6 2.0 1.2 2.5 4.8 6.1 0.1 2.6 4.2 4.9 0.3 4.6 5.5 1.0 4.8 1.6 0.5 0.3 0.6 0.6 0.4 0.4 0.7 0.5 0.7 0.3 0.4 0.5 0.7 0.0 2.4 0.0 6.6 0.1 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.6 1.8 0.0 0.0 30.6 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 18.5 0.1 0.0 0.0 GPR180 ITR ENSG00000152749 "G protein-coupled receptor 180" Q86V85 13 94601857-94634661 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047250 Approved Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA047250: AB_2679998" "unprognostic (3.91e-3)" "unprognostic (3.28e-1)" "unprognostic (4.16e-3)" "unprognostic (2.95e-1)" "unprognostic (1.17e-2)" "unprognostic (1.40e-1)" "unprognostic (3.75e-3)" "unprognostic (2.57e-2)" "unprognostic (2.89e-2)" "unprognostic (6.71e-2)" "unprognostic (1.47e-1)" "unprognostic (2.86e-2)" "prognostic unfavorable (3.18e-5)" "unprognostic (2.49e-2)" "unprognostic (1.10e-1)" "unprognostic (8.47e-2)" "unprognostic (2.80e-2)" 5.8 2.3 3.0 2.4 3.6 0.9 2.6 4.5 4.5 2.7 4.1 2.1 2.0 2.4 1.8 1.7 2.5 1.8 1.8 3.4 3.2 2.5 6.9 2.4 2.4 2.8 3.0 2.4 3.1 2.5 3.5 3.6 3.1 2.5 2.5 7.0 2.8 2.3 1.8 1.9 1.6 2.8 3.6 2.2 2.7 1.1 3.2 2.6 3.6 1.8 2.6 2.3 1.5 3.6 14.6 3.6 5.1 5.4 10.5 11.4 2.1 9.7 7.7 9.3 12.3 4.4 9.8 4.8 4.1 8.4 6.4 9.0 7.3 6.9 12.7 12.7 4.6 9.4 4.9 0.0 8.3 13.6 7.3 6.5 5.8 5.7 7.7 8.3 9.6 6.8 2.7 2.3 9.3 2.1 6.9 3.0 3.3 10.4 4.0 7.8 6.8 2.0 10.4 4.3 7.4 5.3 4.5 9.9 12.2 6.4 7.0 5.5 8.7 5.7 4.6 6.8 8.2 3.8 4.2 2.2 9.5 10.9 7.9 0.1 0.5 0.1 0.8 0.3 1.4 0.5 0.9 0.6 0.9 0.5 1.1 0.9 0.0 0.5 0.4 0.6 1.2 0.4 3.0 3.6 4.5 4.5 3.4 3.2 2.8 3.0 3.1 3.6 3.2 3.6 9.0 3.2 4.1 20.2 6.1 6.0 5.4 11.2 7.4 12.5 7.4 5.5 6.8 7.2 7.8 12.9 31.3 8.7 9.3 3.8 5.9 8.3 1.0 11.1 8.9 8.3 10.3 3.6 47.6 10.2 27.8 11.8 9.7 9.0 5.1 9.2 9.7 30.8 10.5 18.5 30.5 9.8 6.1 4.4 4.9 0.7 9.6 5.3 7.2 18.7 4.1 15.4 9.2 40.7 26.3 9.6 3.7 5.7 16.0 10.6 3.0 7.5 16.8 22.0 6.6 6.3 10.6 3.5 10.6 6.4 4.7 4.1 6.6 3.6 5.5 5.0 GPR37L1 ETBR-LP-2 ENSG00000170075 "G protein-coupled receptor 37 like 1" O60883 1 202122917-202133592 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 76.4" "Cell type enhanced" "Detected in some" "Astrocytes: 91.7;Muller glia cells: 59.6;Oligodendrocyte precursor cells: 89.0;Oligodendrocytes: 20.4" "Cancer enriched" "Detected in some" 57 "glioma: 36.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 1.2;MCF7: 1.5;T-47d: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061629, HPA064454" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 6: T47d - Mammary gland" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Cell Junctions" "Vesicles, Plasma membrane" "HPA061629: , HPA064454: AB_2685268" "unprognostic (2.12e-2)" "unprognostic (1.83e-1)" "unprognostic (2.96e-1)" "unprognostic (1.61e-3)" "unprognostic (4.52e-1)" "unprognostic (8.20e-2)" "unprognostic (2.26e-4)" "unprognostic (5.83e-2)" "unprognostic (3.46e-3)" "unprognostic (2.07e-1)" "unprognostic (1.83e-1)" "unprognostic (3.28e-2)" "unprognostic (4.86e-3)" "unprognostic (1.14e-1)" "unprognostic (4.58e-2)" "unprognostic (1.18e-3)" "unprognostic (3.49e-1)" 0.1 0.2 55.2 0.0 71.1 0.2 0.0 60.7 52.2 0.2 10.6 0.9 0.2 0.1 0.1 0.1 0.1 0.0 0.1 48.0 50.7 0.0 0.2 0.0 0.0 66.7 67.0 0.0 0.0 0.0 0.6 0.0 53.7 0.2 0.2 2.8 0.1 0.3 0.1 0.1 0.3 0.1 59.4 0.0 0.2 0.3 76.4 0.0 0.1 0.1 0.0 0.0 0.1 53.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 55.2 71.1 60.7 52.2 48.0 50.7 66.7 67.0 53.7 59.4 76.4 53.1 0.0 0.0 0.0 91.7 0.1 0.4 0.5 0.7 0.0 1.2 0.3 0.3 1.1 1.5 1.7 0.0 4.2 0.1 0.0 4.9 0.0 3.2 4.5 0.9 0.2 0.1 0.0 0.0 0.4 1.2 1.0 0.2 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.5 1.1 0.0 0.0 0.0 0.8 0.9 0.1 0.0 2.8 0.0 59.6 0.0 89.0 20.4 2.1 2.7 1.9 0.0 0.8 1.3 0.1 1.1 4.9 0.0 0.5 0.1 0.0 0.1 0.0 0.1 0.7 0.1 0.2 0.7 1.0 GPR65 "hTDAG8, TDAG8" ENSG00000140030 "G protein-coupled receptor 65" Q8IYL9 14 88005135-88014811 "G-protein coupled receptors, Predicted membrane proteins" Apoptosis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.6;lymphoid tissue: 9.6" "Cell type enhanced" "Detected in many" "dendritic cells: 256.1;granulocytes: 317.8;Kupffer cells: 112.5;monocytes: 90.9;NK-cells: 319.3;T-cells: 192.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 5.7;HEL: 6.2;HL-60: 7.5;HMC-1: 9.0;RH-30: 11.5" "Not detected" "Not detected" "HPA072624, HPA077397" Enhanced Approved Nucleoli,Vesicles,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Nucleoli, Cytosol" "HPA072624: , HPA077397: " "unprognostic (8.56e-2)" "unprognostic (8.65e-3)" "unprognostic (1.98e-3)" "unprognostic (3.59e-3)" "unprognostic (3.10e-1)" "unprognostic (3.55e-3)" "unprognostic (1.15e-1)" "unprognostic (3.01e-2)" "unprognostic (3.62e-2)" "unprognostic (1.35e-1)" "unprognostic (1.08e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (4.99e-4)" "unprognostic (3.79e-1)" "unprognostic (4.46e-3)" "unprognostic (9.03e-2)" "unprognostic (3.80e-1)" 2.0 1.1 0.5 9.1 0.6 12.6 0.9 0.5 0.8 1.1 0.6 1.2 1.6 0.7 0.4 0.9 0.7 2.8 0.6 0.4 1.0 0.8 2.7 4.3 8.8 1.9 1.0 0.3 0.4 0.4 0.4 1.7 1.6 0.8 1.5 0.1 0.7 0.5 0.2 0.3 2.4 2.3 1.0 9.6 1.6 0.6 1.2 4.2 0.4 0.5 6.6 3.4 0.5 2.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.2 0.0 0.0 0.2 7.5 9.0 0.3 0.0 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.7 1.0 0.0 0.0 0.0 0.2 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 39.0 19.8 43.6 33.8 28.4 62.4 9.3 16.9 26.2 13.0 8.1 8.6 19.4 15.2 49.1 32.1 5.9 9.0 24.5 0.5 0.6 0.5 0.8 0.4 1.0 1.9 1.0 1.6 1.0 1.2 2.3 2.9 3.2 21.6 0.3 77.8 4.2 0.5 0.0 0.0 0.2 1.9 3.2 0.4 7.2 1.3 0.0 0.0 0.2 256.1 0.5 0.0 0.0 9.1 0.2 0.4 2.1 0.0 6.6 0.0 0.0 0.3 2.3 6.6 0.5 317.8 0.0 3.9 1.4 62.8 0.0 0.0 0.6 0.0 112.5 73.1 1.4 0.6 88.6 3.6 4.7 90.9 0.0 319.3 0.0 0.1 0.0 0.0 0.0 25.6 0.2 0.1 0.3 0.7 0.2 0.0 0.9 2.0 0.1 0.1 0.7 5.3 0.4 192.8 0.9 0.4 0.2 GPRC5A "PEIG-1, RAI3, RAIG1, TIG1" ENSG00000013588 "G protein-coupled receptor class C group 5 member A" Q8NFJ5 12 12891559-12917937 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 201.9;urinary bladder: 130.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 939.1;Club cells: 357.8;Distal enterocytes: 477.9;Pancreatic endocrine cells: 600.7;Paneth cells: 359.8;Urothelial cells: 1252.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 355.6;A549: 285.7;CAPAN-2: 1347.4;HaCaT: 351.2;SiHa: 492.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA007928, HPA046526" Enhanced Enhanced "Vesicles,Plasma membrane" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Plasma membrane" "HPA007928: AB_1849318, HPA046526: AB_2679685" "unprognostic (4.79e-2)" "unprognostic (8.35e-2)" "unprognostic (4.21e-2)" "unprognostic (1.64e-1)" "unprognostic (4.65e-3)" "unprognostic (1.73e-1)" "unprognostic (2.38e-2)" "unprognostic (1.89e-2)" "unprognostic (3.48e-1)" "unprognostic (8.69e-3)" "prognostic unfavorable (4.63e-6)" "unprognostic (3.81e-1)" "prognostic unfavorable (9.02e-5)" "unprognostic (9.30e-2)" "unprognostic (4.34e-1)" "unprognostic (1.62e-2)" "unprognostic (2.49e-1)" 31.5 3.7 1.2 11.5 0.9 1.8 9.6 1.0 1.4 35.4 3.4 56.4 18.7 8.9 0.4 23.0 9.8 24.9 18.9 1.8 0.8 9.0 1.8 201.9 0.2 2.7 4.5 21.4 2.7 0.9 2.5 13.5 1.0 10.2 48.4 1.6 23.5 1.3 0.7 5.8 20.9 5.1 0.5 0.4 33.6 1.5 2.1 0.3 55.5 0.6 4.4 130.8 30.6 1.8 355.6 285.7 0.1 1.3 3.4 1.5 18.4 105.2 39.5 66.2 49.4 49.1 1347.4 0.1 8.6 83.3 67.2 351.2 1.0 50.1 101.7 0.4 4.3 0.2 105.4 2.2 23.8 0.1 0.3 1.8 66.5 27.5 6.7 82.3 40.9 0.0 0.5 0.3 2.9 251.7 0.2 0.3 1.6 130.0 43.5 0.2 6.7 0.3 133.6 69.6 0.5 0.6 492.0 36.8 15.9 52.3 10.9 1.0 4.0 2.6 83.9 156.1 4.3 0.2 0.3 0.3 34.6 0.3 2.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 1.2 0.9 1.0 1.4 1.8 0.8 2.7 4.5 1.0 0.5 2.1 1.8 10.0 939.1 200.2 0.0 1.0 12.5 329.6 202.8 4.6 0.1 80.6 41.7 1.9 11.5 357.8 46.0 0.0 3.8 1.5 477.9 0.0 46.9 0.1 91.8 54.1 15.8 8.3 0.0 0.2 72.1 11.7 108.5 176.9 288.1 10.1 0.2 8.6 0.2 1.6 0.0 0.4 43.5 61.1 0.3 18.0 0.4 13.4 9.6 51.6 0.0 0.6 3.5 0.0 0.0 0.1 600.7 359.8 10.1 0.5 320.1 114.0 0.2 86.3 0.4 0.0 23.0 38.8 1.5 0.3 22.7 9.1 1.1 4.9 0.7 110.4 1252.7 GPRC5B RAIG-2 ENSG00000167191 "G protein-coupled receptor class C group 5 member B" Q9NZH0 16 19856691-19886167 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 490.3" "Cell type enhanced" "Detected in many" "Early spermatids: 197.7;Late spermatids: 269.9;Oligodendrocytes: 171.0" "Cancer enhanced" "Detected in all" "glioma: 52.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 2.8" "Lineage enhanced" "Detected in single" "T-cells: 2.8" "Cell line enhanced" "Detected in many" "EFO-21: 92.5;HHSteC: 60.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015247 Enhanced Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 34: Spermatids - Unknown function" Vesicles "Nucleoplasm, Nucleoli" "HPA015247: AB_1849323" "unprognostic (1.26e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (9.27e-5)" "unprognostic (2.60e-3)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (3.97e-2)" "unprognostic (5.70e-2)" "unprognostic (1.42e-1)" "unprognostic (2.26e-2)" "unprognostic (2.76e-2)" "unprognostic (1.27e-1)" "prognostic favorable (6.30e-4)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (4.42e-3)" "unprognostic (6.78e-3)" 25.3 7.0 249.1 4.4 428.3 0.1 19.6 365.2 263.4 12.8 13.1 8.1 5.7 13.1 14.8 8.1 20.1 15.3 40.7 245.8 278.4 22.4 3.2 5.8 7.8 379.4 327.1 22.6 21.7 45.9 14.1 15.7 333.0 9.6 2.4 17.4 40.1 17.7 72.7 7.5 11.1 7.5 262.7 2.5 41.3 34.0 315.0 3.2 13.8 73.8 3.4 12.8 8.6 490.3 1.2 29.9 29.0 5.2 29.3 2.0 5.3 0.3 7.4 2.9 1.8 28.0 1.0 0.0 92.5 1.0 18.9 1.6 21.6 0.2 1.7 0.2 8.6 0.0 0.1 0.0 60.3 0.0 0.0 2.5 0.0 4.9 0.0 7.9 14.3 0.7 6.6 0.6 6.7 1.5 0.1 0.1 31.8 0.0 15.6 8.9 0.0 0.2 1.1 13.8 22.9 1.9 3.6 1.9 27.2 9.1 0.1 0.6 2.9 0.0 3.5 14.4 0.8 0.4 0.1 0.3 1.4 0.3 1.8 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.7 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.1 0.0 0.0 0.5 249.1 428.3 365.2 263.4 245.8 278.4 379.4 327.1 333.0 262.7 315.0 490.3 71.4 0.0 3.0 75.4 1.2 1.3 5.3 2.6 9.1 30.7 22.5 16.3 15.7 40.0 7.2 31.3 0.0 5.0 0.3 0.2 1.9 65.3 197.7 4.1 20.7 44.8 0.0 0.0 2.4 64.5 1.4 14.8 31.6 13.7 0.0 0.4 9.3 0.2 4.1 0.0 13.5 0.0 38.7 1.6 2.6 269.9 23.9 2.2 16.0 7.5 1.0 24.8 0.0 51.8 171.0 72.8 0.0 26.7 1.3 12.3 0.0 0.3 3.3 6.0 13.1 3.3 13.0 4.9 1.6 2.4 1.7 2.5 0.8 7.0 0.2 1.6 GPRIN1 "GRIN1, KIAA1893" ENSG00000169258 "G protein regulated inducer of neurite outgrowth 1" Q7Z2K8 5 176595802-176610156 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 22.1;pituitary gland: 8.1;retina: 6.9" "Group enriched" "Detected in some" 4 "Bipolar cells: 12.8;Excitatory neurons: 7.5;Horizontal cells: 21.9;Inhibitory neurons: 8.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 56.5;SCLC-21H: 59.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036478, HPA070892" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" Vesicles "HPA036478: AB_2675145, HPA070892: AB_2686321" "unprognostic (1.70e-1)" "unprognostic (7.38e-2)" "unprognostic (4.41e-2)" "unprognostic (5.66e-2)" "unprognostic (6.54e-3)" "unprognostic (3.06e-1)" "unprognostic (4.76e-6)" "prognostic unfavorable (6.83e-6)" "unprognostic (1.11e-1)" "unprognostic (1.45e-1)" "unprognostic (2.59e-3)" "unprognostic (1.56e-3)" "prognostic unfavorable (2.79e-7)" "unprognostic (4.24e-3)" "unprognostic (5.60e-2)" "unprognostic (2.21e-1)" "unprognostic (3.32e-3)" 0.5 1.6 16.9 0.8 15.9 0.2 0.3 6.8 19.5 0.3 0.0 1.1 3.8 0.4 0.0 0.8 0.1 0.3 0.4 22.1 15.7 0.6 0.4 0.4 0.8 4.3 3.5 0.0 0.6 0.1 8.1 0.3 5.1 0.2 0.4 6.9 0.3 0.0 0.3 1.0 3.2 0.7 3.3 0.4 0.8 1.5 14.8 0.9 0.2 0.2 1.1 0.3 0.2 6.6 7.5 7.9 9.8 14.1 2.1 4.6 8.3 9.8 5.1 7.5 9.7 9.6 4.8 17.0 19.6 5.3 22.0 6.5 6.3 6.8 6.5 56.5 4.3 0.3 4.1 3.4 0.9 0.4 4.2 2.3 5.1 8.1 1.2 1.5 5.5 3.8 9.1 24.0 6.3 19.7 1.8 0.0 9.9 5.0 15.4 31.7 10.9 10.1 8.4 7.7 59.5 34.1 11.4 3.2 17.7 1.2 7.4 6.5 6.8 13.8 16.0 5.3 14.5 0.4 2.3 4.8 11.9 0.8 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 15.9 6.8 19.5 22.1 15.7 4.3 3.5 5.1 3.3 14.8 6.6 0.4 0.0 0.0 0.3 0.5 2.4 0.1 0.3 0.6 12.8 0.4 0.3 0.3 0.0 0.1 0.0 0.0 0.1 0.4 0.3 1.9 0.4 0.0 0.5 0.6 1.0 1.8 0.0 7.5 1.8 0.9 0.4 0.0 1.2 0.0 0.3 0.0 0.0 0.9 21.9 8.0 0.3 0.0 0.0 0.3 0.0 0.3 0.2 0.0 1.9 0.1 1.1 1.0 2.5 0.3 1.6 0.1 0.0 0.8 0.2 0.0 0.3 0.4 3.1 0.0 1.5 0.3 0.7 2.7 0.4 1.4 0.1 0.3 0.4 0.2 0.1 GRAMD1B "KIAA1201, LINC01059" ENSG00000023171 "GRAM domain containing 1B" Q3KR37 11 123358428-123627774 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 258.8;choroid plexus: 91.8;retina: 96.7" "Cell type enhanced" "Detected in many" "Astrocytes: 94.7;Cone photoreceptor cells: 114.7;Excitatory neurons: 120.7;Inhibitory neurons: 102.8;Oligodendrocyte precursor cells: 95.0;Rod photoreceptor cells: 92.3;Theca cells: 109.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 7.0" "Lineage enriched" "Detected in many" 4 "dendritic cells: 7.0" "Group enriched" "Detected in many" 4 "A549: 62.4;HDLM-2: 168.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008557, HPA075204" Approved Supported "Endoplasmic reticulum,Vesicles,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 58: Brain - Synaptic function" "Cluster 44: HDLM-2 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum, Plasma membrane" Vesicles "HPA008557: AB_1079197, HPA075204: " "unprognostic (1.86e-1)" "unprognostic (7.18e-3)" "unprognostic (2.43e-2)" "unprognostic (2.74e-3)" "unprognostic (8.15e-2)" "unprognostic (4.28e-2)" "unprognostic (2.69e-3)" "unprognostic (4.12e-3)" "unprognostic (1.40e-1)" "unprognostic (2.90e-2)" "unprognostic (9.60e-2)" "unprognostic (8.06e-2)" "prognostic unfavorable (4.30e-7)" "unprognostic (1.39e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (1.69e-1)" 1.8 258.8 22.5 4.3 27.4 18.6 1.1 80.1 52.3 0.9 91.8 1.6 34.6 1.1 9.4 0.6 3.6 12.1 15.0 55.6 19.4 15.5 1.5 2.6 5.4 25.7 20.1 15.2 2.4 0.7 16.6 5.0 24.2 1.1 1.1 96.7 1.9 2.0 3.4 0.5 25.2 1.2 9.4 3.6 11.4 16.8 33.5 6.6 4.9 2.2 3.5 1.2 0.8 26.1 0.1 62.4 3.5 0.1 0.3 0.7 9.5 20.5 14.6 4.1 1.8 2.6 0.4 3.8 10.4 10.1 6.8 0.0 6.2 0.0 4.3 168.5 5.0 0.0 28.3 0.7 0.0 22.1 0.0 1.0 0.1 7.1 0.0 5.2 1.8 1.6 0.0 0.2 3.7 0.5 3.8 7.2 7.6 28.3 23.0 10.8 9.8 6.8 0.2 0.0 20.0 16.3 4.9 0.5 0.1 8.1 0.5 12.0 12.3 23.8 3.2 4.2 1.0 0.0 0.0 0.0 4.6 20.5 1.1 0.0 1.2 0.4 0.4 0.7 0.2 0.0 1.5 1.2 1.7 0.0 0.2 0.2 0.1 1.6 0.7 7.0 0.7 0.5 22.5 27.4 80.1 52.3 55.6 19.4 25.7 20.1 24.2 9.4 33.5 26.1 1.4 0.0 0.5 94.7 0.6 0.0 0.0 0.1 1.2 44.3 1.1 1.0 5.7 21.5 0.2 5.5 114.7 6.9 17.9 0.1 3.9 0.7 9.6 1.6 0.6 1.0 0.0 0.0 120.7 0.4 3.7 1.6 16.3 0.9 0.0 41.9 0.7 0.0 2.6 45.4 102.8 1.8 0.0 3.8 2.6 2.7 0.6 7.5 0.0 37.5 2.5 23.4 0.0 95.0 5.5 3.9 1.3 0.7 2.4 0.1 17.3 8.9 0.4 92.3 0.0 3.0 4.2 3.9 1.9 0.1 0.4 2.5 7.2 109.3 1.5 0.0 GRB10 ENSG00000106070 "Growth factor receptor bound protein 10" Q13322 7 50590063-50793462 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Early spermatids: 143.0;Late spermatids: 212.6;Oligodendrocytes: 124.7;Rod photoreceptor cells: 81.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 10.0;eosinophil: 3.0" "Lineage enriched" "Detected in single" 28 "granulocytes: 10.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB019423, HPA027502, HPA031818" Enhanced Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 54: Non-specific - Microtubule organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "CAB019423: AB_2112883, HPA027502: AB_10602325, HPA031818: AB_2674057" "unprognostic (2.82e-2)" "unprognostic (1.69e-3)" "unprognostic (1.25e-2)" "unprognostic (1.45e-2)" "unprognostic (3.68e-2)" "unprognostic (1.60e-1)" "unprognostic (6.83e-2)" "unprognostic (5.91e-3)" "unprognostic (1.67e-2)" "unprognostic (2.31e-3)" "unprognostic (4.44e-1)" "unprognostic (2.07e-1)" "unprognostic (1.23e-3)" "unprognostic (1.73e-3)" "unprognostic (8.16e-3)" "unprognostic (2.63e-2)" "unprognostic (8.50e-2)" 27.6 26.0 29.5 6.5 33.6 10.0 25.0 25.2 32.5 18.2 28.5 27.2 17.2 19.8 10.3 9.5 18.8 21.6 34.8 26.5 40.2 29.3 32.1 20.6 6.0 31.5 41.8 14.2 94.3 10.5 24.3 14.7 40.2 20.1 6.4 83.5 16.5 15.0 57.4 9.1 13.3 16.1 21.6 36.8 17.6 18.1 48.2 2.8 27.8 76.0 4.0 31.0 15.9 33.5 0.3 32.5 51.6 21.1 23.5 17.8 27.6 13.1 11.3 24.9 29.7 19.8 0.4 0.7 22.6 16.7 71.0 3.1 53.5 13.9 12.2 0.4 21.6 56.7 32.6 14.4 49.8 36.0 84.1 46.4 21.0 38.6 37.4 23.9 62.7 3.9 109.5 0.6 18.7 4.0 6.4 48.0 56.9 27.2 55.4 16.8 0.0 0.3 16.0 13.1 22.7 0.2 1.6 8.1 68.7 33.0 27.7 71.6 78.7 21.8 29.6 45.4 50.4 2.1 0.7 0.4 68.9 32.2 75.2 10.0 0.1 3.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 29.5 33.6 25.2 32.5 26.5 40.2 31.5 41.8 40.2 21.6 48.2 33.5 46.3 6.4 8.3 3.9 1.2 7.5 5.3 9.4 7.4 12.1 14.8 9.0 13.5 47.1 5.2 5.5 87.6 4.5 0.3 6.9 1.9 18.3 143.0 5.3 12.4 45.2 0.0 19.0 64.8 24.4 16.5 15.4 5.6 9.7 0.0 0.8 53.2 26.8 1.6 5.0 55.0 2.8 6.1 9.7 5.5 212.6 1.8 4.0 7.2 40.3 0.8 21.8 0.0 41.7 124.7 36.4 3.0 0.4 0.6 22.2 11.2 22.2 2.3 81.9 0.0 9.2 10.9 1.9 16.2 1.2 4.3 2.6 1.5 0.9 3.8 7.0 GRHL1 "LBP-32, MGR, TFCP2L2" ENSG00000134317 "Grainyhead like transcription factor 1" Q9NZI5 2 9951693-10002277 "Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 119.6;skin 1: 87.7;vagina: 66.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 62.6;Cytotrophoblasts: 61.9;Extravillous trophoblasts: 80.5;Suprabasal keratinocytes: 132.7;Syncytiotrophoblasts: 184.6;Urothelial cells: 104.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "eosinophil: 2.2" "Lineage enriched" "Detected in single" 8 "granulocytes: 2.2" "Cell line enhanced" "Detected in many" "BEWO: 212.3;RT4: 41.4;SK-BR-3: 112.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA005798, HPA006420" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm Vesicles "HPA005798: AB_1079026, HPA006420: AB_1079025" "unprognostic (2.26e-3)" "unprognostic (5.80e-2)" "unprognostic (8.35e-2)" "unprognostic (7.33e-3)" "unprognostic (2.70e-1)" "unprognostic (2.76e-2)" "unprognostic (4.43e-3)" "unprognostic (6.73e-2)" "unprognostic (1.68e-1)" "unprognostic (1.00e-1)" "unprognostic (8.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.14e-4)" "unprognostic (3.66e-1)" "unprognostic (3.40e-1)" "unprognostic (4.04e-2)" "unprognostic (2.14e-1)" 4.5 1.3 2.2 1.2 2.3 8.7 39.8 0.8 2.8 31.0 1.0 1.5 1.2 1.0 7.3 119.6 2.2 3.0 2.5 2.7 2.5 4.0 12.2 5.0 1.0 0.8 1.5 0.4 4.2 29.0 3.6 26.7 0.9 11.4 1.0 11.4 44.7 7.3 1.1 87.7 0.7 0.7 0.6 0.8 3.7 3.2 4.3 0.9 2.9 0.4 26.1 13.9 66.9 1.7 10.9 0.2 1.2 3.0 0.4 0.5 212.3 1.0 1.5 0.7 1.2 0.9 7.5 1.4 0.4 0.1 1.5 6.5 13.0 1.4 3.1 3.2 5.9 0.3 2.3 4.3 0.3 0.7 1.2 0.4 5.5 6.0 0.0 0.0 1.1 2.3 2.2 4.1 0.0 14.3 2.2 1.7 0.8 3.5 2.5 0.9 1.0 1.9 1.4 41.4 2.4 1.6 2.0 112.3 2.7 17.4 13.7 0.4 1.2 0.6 2.6 3.3 1.3 2.7 1.7 1.5 0.6 1.7 1.8 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.2 1.7 2.2 2.3 0.8 2.8 2.7 2.5 0.8 1.5 0.9 0.6 4.3 1.7 2.2 3.2 8.1 3.9 1.2 40.0 23.1 10.7 2.8 25.5 37.1 19.9 2.1 1.5 31.1 20.2 62.6 61.9 1.3 1.2 0.0 2.9 6.4 4.5 1.3 4.2 3.5 0.0 14.6 9.1 80.5 5.4 3.1 9.6 10.2 0.4 2.5 7.7 7.7 11.8 6.0 0.8 4.1 1.0 15.7 3.0 0.0 10.6 21.4 1.9 1.0 1.1 0.0 4.0 1.0 5.7 0.1 0.4 1.0 31.5 0.1 2.4 18.6 11.5 0.0 3.0 3.7 9.6 5.1 35.2 132.7 184.6 2.1 0.1 1.2 104.6 GRIK1 "GluK1, GLUR5" ENSG00000171189 "Glutamate ionotropic receptor kainate type subunit 1" P39086 21 29536933-29940033 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "adrenal gland: 12.5;brain: 32.6;retina: 38.2" "Group enriched" "Detected in some" 10 "Inhibitory neurons: 2260.1;Oligodendrocyte precursor cells: 862.5" "Cancer enriched" "Detected in some" 5 "glioma: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Daudi: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014623, HPA073879" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Vesicles "HPA014623: AB_1850305, HPA073879: " "unprognostic (1.39e-1)" "unprognostic (6.54e-2)" "unprognostic (1.32e-1)" "unprognostic (1.04e-2)" "unprognostic (1.03e-3)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (2.12e-3)" "unprognostic (1.25e-1)" "unprognostic (8.77e-2)" "unprognostic (4.89e-3)" "unprognostic (1.20e-3)" "unprognostic (1.47e-8)" "unprognostic (2.09e-1)" "unprognostic (2.68e-1)" "unprognostic (1.09e-1)" "unprognostic (3.15e-3)" 0.2 12.5 7.5 0.2 6.6 0.1 1.8 2.4 6.0 0.8 0.0 0.3 0.0 0.1 2.0 0.3 0.0 0.1 0.0 8.4 12.3 0.0 0.1 0.1 0.1 30.0 11.2 0.3 0.0 0.0 0.2 0.4 32.6 2.4 0.5 38.2 0.0 0.1 0.1 0.8 0.4 0.1 2.6 0.1 0.2 0.5 9.7 0.0 0.0 0.0 0.0 0.4 0.4 2.9 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.5 6.6 2.4 6.0 8.4 12.3 30.0 11.2 32.6 2.6 9.7 2.9 0.1 0.0 0.0 27.4 0.0 0.3 0.0 0.0 0.0 149.8 2.3 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.8 0.1 1.2 0.4 0.0 0.0 29.8 0.0 0.0 0.7 0.0 0.2 0.0 148.8 0.0 0.0 0.1 1.7 2260.1 0.0 0.0 0.0 0.4 13.2 0.3 0.2 3.6 10.3 0.0 2.5 0.0 862.5 8.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 4.9 0.0 0.0 5.7 0.0 0.0 0.0 0.1 0.0 0.1 33.8 0.1 0.0 GRIPAP1 "DKFZp434P0630, GRASP-1, GRASP1, KIAA1167, MPMGp800B12492Q3" ENSG00000068400 "GRIP1 associated protein 1" Q4V328 X 48973720-49002264 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 212.7;Rod photoreceptor cells: 169.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000282, HPA000615" Approved Approved Vesicles,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "Vesicles, Cytosol" "HPA000282: AB_1079022, HPA000615: AB_1079023" "unprognostic (3.34e-1)" "unprognostic (2.86e-3)" "unprognostic (3.24e-3)" "unprognostic (3.93e-3)" "unprognostic (2.68e-1)" "unprognostic (1.23e-1)" "unprognostic (3.97e-3)" "unprognostic (1.01e-2)" "unprognostic (5.26e-2)" "unprognostic (3.65e-1)" "unprognostic (1.69e-3)" "unprognostic (1.06e-2)" "prognostic unfavorable (3.92e-7)" "unprognostic (4.24e-3)" "unprognostic (2.30e-1)" "unprognostic (1.05e-1)" "prognostic favorable (4.63e-7)" 17.2 23.8 30.6 23.6 31.7 35.3 16.6 28.0 35.5 19.6 19.6 19.3 19.0 17.5 24.7 19.3 19.3 13.3 15.3 31.4 30.4 20.6 22.0 21.3 25.4 29.2 29.6 19.9 15.4 22.9 33.6 15.6 29.9 19.0 15.4 48.1 16.7 15.5 18.4 24.4 21.9 14.7 23.1 28.1 19.4 19.7 30.1 26.1 20.9 12.9 24.1 18.0 17.5 32.2 27.9 43.6 30.7 64.3 18.1 13.8 27.7 22.4 27.6 28.3 26.7 23.7 24.0 42.1 12.6 22.3 30.4 39.0 38.5 24.5 22.6 49.3 19.7 34.0 59.8 25.2 31.1 36.7 58.3 14.4 34.5 37.7 27.8 26.2 26.1 35.6 25.2 54.3 26.3 51.5 32.2 49.3 36.3 19.8 23.5 35.3 46.1 33.8 28.0 34.1 27.0 30.0 47.6 18.8 28.4 44.4 42.6 72.5 31.3 14.9 23.2 30.7 18.5 33.0 27.6 29.6 25.9 54.9 25.9 32.5 14.6 21.3 10.1 13.3 8.6 11.3 10.4 9.7 12.0 13.6 8.9 9.5 25.9 15.7 13.0 12.4 9.0 9.5 30.6 31.7 28.0 35.5 31.4 30.4 29.2 29.6 29.9 23.1 30.1 32.2 22.6 9.6 25.1 13.7 28.6 8.2 15.5 25.2 10.8 67.6 11.6 9.1 13.9 22.8 26.7 18.4 212.7 21.2 30.1 25.8 29.4 15.5 9.3 23.8 19.3 21.2 21.7 17.2 32.1 18.4 9.9 14.4 26.0 26.3 43.1 31.2 18.5 18.5 17.2 69.0 32.9 22.4 34.6 27.0 18.7 14.4 17.1 28.5 7.2 10.3 32.7 25.3 33.0 18.1 17.7 18.4 30.6 19.2 22.2 16.9 23.9 19.1 25.5 169.4 19.7 16.9 17.8 11.5 10.1 16.6 14.2 26.1 25.1 35.8 16.5 19.5 GRM1 "GPRC1A, mGlu1, MGLUR1, PPP1R85" ENSG00000152822 "Glutamate metabotropic receptor 1" Q13255 6 146027646-146437601 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 27.6" "Group enriched" "Detected in some" 6 "Excitatory neurons: 215.5;Inhibitory neurons: 138.8;Rod photoreceptor cells: 124.9" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebellum: 27.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA015701 Approved Supported Approved Vesicles NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA015701: AB_1853917" "unprognostic (1.04e-2)" "unprognostic (7.33e-2)" "unprognostic (3.73e-3)" "unprognostic (9.77e-3)" "unprognostic (6.75e-2)" "unprognostic (2.13e-1)" "unprognostic (1.09e-1)" "unprognostic (5.78e-2)" "unprognostic (4.31e-2)" "unprognostic (2.93e-2)" "unprognostic (9.48e-3)" "unprognostic (7.92e-2)" "unprognostic (1.84e-2)" "unprognostic (1.03e-1)" "unprognostic (3.50e-2)" "unprognostic (8.33e-3)" "unprognostic (9.76e-2)" 0.0 0.0 3.3 0.0 3.6 0.0 0.0 27.6 6.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 7.3 2.3 0.7 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 5.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 7.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 3.6 27.6 6.8 7.3 2.3 0.0 3.1 0.9 0.0 7.7 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 13.8 0.0 0.0 3.7 0.0 0.0 1.8 16.7 0.0 0.0 0.0 1.9 0.0 8.5 0.1 0.0 0.2 0.0 0.0 215.5 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.6 6.7 138.8 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 3.7 0.0 4.0 0.0 8.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 124.9 0.0 0.0 0.1 1.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GSAP "LOC54103, PION" ENSG00000186088 "Gamma-secretase activating protein" A4D1B5 7 77310751-77416349 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;NK-cells: 110.2;Oligodendrocyte precursor cells: 72.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 12.5;U-937: 17.0" "Region enhanced" "Detected in all" "cerebellum: 15.5" "Low region specificity" "Detected in all" HPA023994 Approved Vesicles NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 64: Macrophages - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA023994: AB_1855386" "prognostic favorable (3.36e-4)" "unprognostic (3.70e-1)" "unprognostic (8.55e-3)" "unprognostic (4.53e-3)" "unprognostic (6.80e-3)" "unprognostic (3.52e-3)" "unprognostic (4.36e-2)" "unprognostic (7.18e-3)" "unprognostic (1.09e-1)" "unprognostic (9.98e-3)" "unprognostic (2.07e-3)" "unprognostic (2.41e-1)" "prognostic unfavorable (3.51e-4)" "unprognostic (3.61e-1)" "unprognostic (1.82e-2)" "unprognostic (9.49e-2)" "prognostic favorable (4.15e-5)" 5.3 5.3 2.5 10.9 2.2 9.4 5.9 1.8 3.4 3.7 3.2 5.0 2.6 4.0 3.8 3.1 6.4 7.9 4.9 2.4 4.1 6.3 16.4 18.4 13.1 3.6 2.9 3.6 5.4 11.8 7.4 3.8 3.0 5.4 4.7 10.9 4.7 5.1 2.0 4.4 7.5 3.8 2.8 18.7 7.8 1.9 4.2 6.1 8.3 3.9 13.0 5.9 2.3 4.1 3.8 2.0 0.0 0.0 0.5 2.4 0.4 2.3 7.7 1.2 3.2 0.6 5.4 0.8 0.2 0.1 4.3 1.8 0.1 1.9 3.4 2.5 1.6 4.1 0.2 10.7 3.3 0.3 0.0 0.9 7.0 6.2 12.5 9.2 0.5 0.0 0.1 0.3 10.5 2.1 0.0 8.2 0.6 6.0 2.7 0.0 0.2 0.2 6.9 3.2 0.2 5.7 2.5 1.2 6.3 0.5 2.3 3.4 0.0 2.0 1.4 0.2 7.1 1.5 0.1 1.4 8.8 17.0 1.6 0.0 13.3 1.4 8.5 12.7 5.2 18.6 2.8 6.0 16.3 16.4 3.6 6.1 1.7 16.7 9.4 0.4 0.1 8.2 2.5 2.2 1.8 3.4 2.4 4.1 3.6 2.9 3.0 2.8 4.2 4.1 15.2 76.9 60.8 29.0 53.3 5.2 11.6 19.3 13.6 17.0 12.5 9.8 8.5 11.5 22.8 3.7 16.7 3.2 60.5 0.7 25.4 8.5 0.1 10.2 1.6 9.2 5.4 4.4 28.2 6.2 0.7 4.9 9.7 15.8 13.3 9.8 3.3 17.2 9.7 20.2 51.9 6.1 10.2 38.2 23.3 0.2 5.3 46.5 8.8 42.2 30.8 41.6 110.2 72.4 12.7 6.8 4.6 3.8 15.4 20.0 1.4 12.0 9.8 20.9 6.6 9.8 3.2 2.5 1.5 8.6 4.5 1.6 22.8 2.0 4.6 17.2 GSKIP C14orf129 ENSG00000100744 "GSK3B interacting protein" Q9P0R6 14 96363452-96387288 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 166.1;Early spermatids: 384.9;Late spermatids: 321.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043054, HPA046782" Approved Approved "Nucleoli,Golgi apparatus,Vesicles" No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 15: RT4 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Golgi apparatus, Vesicles" Nucleoli "HPA043054: AB_2678293, HPA046782: AB_2679803" "unprognostic (3.48e-1)" "unprognostic (1.16e-1)" "unprognostic (1.68e-2)" "unprognostic (5.08e-2)" "unprognostic (1.58e-1)" "unprognostic (1.04e-1)" "unprognostic (6.23e-3)" "unprognostic (1.11e-1)" "unprognostic (9.35e-2)" "unprognostic (1.16e-3)" "unprognostic (6.82e-2)" "unprognostic (2.84e-1)" "unprognostic (8.74e-3)" "unprognostic (4.67e-2)" "unprognostic (1.52e-1)" "unprognostic (1.48e-2)" "unprognostic (2.30e-1)" 11.4 13.1 13.6 17.5 16.7 16.2 13.2 14.7 16.7 10.4 10.9 60.4 48.3 10.6 11.3 41.0 10.9 14.2 11.0 15.7 14.8 16.4 23.3 9.7 19.6 12.9 12.0 6.7 9.9 9.5 8.1 13.8 13.3 13.9 54.6 67.8 12.1 9.9 12.7 14.5 56.6 15.9 13.9 11.8 23.3 48.7 13.7 11.1 10.3 10.6 22.4 21.1 16.2 14.9 21.9 30.5 33.6 23.1 25.2 29.1 56.6 39.7 30.7 26.2 28.8 22.7 36.6 20.9 23.6 30.4 15.9 23.8 22.1 24.2 37.9 49.9 21.1 8.8 16.1 17.5 23.4 23.1 14.5 23.2 37.7 33.1 32.7 20.1 34.6 23.5 19.2 18.7 33.6 53.5 17.0 18.6 37.3 33.9 38.3 16.7 31.4 19.3 61.5 79.9 11.8 38.4 44.8 41.6 34.9 33.7 31.9 14.3 37.8 12.0 15.1 25.6 12.8 21.7 67.0 17.8 30.6 16.4 19.6 64.4 20.9 47.0 27.7 24.3 42.8 38.3 37.6 32.4 21.2 33.1 37.0 34.5 40.9 37.5 33.6 17.9 66.6 28.6 13.6 16.7 14.7 16.7 15.7 14.8 12.9 12.0 13.3 13.9 13.7 14.9 12.6 12.8 7.4 5.9 24.8 45.2 24.2 27.6 19.9 26.8 18.4 14.5 18.9 14.3 21.7 20.2 41.7 42.7 17.9 166.1 72.4 34.1 384.9 32.3 11.1 17.4 28.1 24.0 14.3 39.4 43.3 12.1 41.8 32.2 19.7 6.6 17.9 17.3 23.6 23.5 10.8 73.0 52.9 19.8 19.6 321.7 8.1 16.8 19.6 5.6 25.2 22.3 16.5 10.6 17.9 39.9 102.9 7.9 22.6 37.4 81.8 47.4 28.6 104.0 19.7 6.5 16.5 40.0 34.1 35.7 65.9 119.6 24.4 7.9 69.1 43.7 GSPT1 "eRF3a, ETF3A, GST1" ENSG00000103342 "G1 to S phase transition 1" P15170 16 11868128-11916082 "Plasma proteins, Predicted intracellular proteins" "Nonsense-mediated mRNA decay, Protein biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052488, HPA074588" Approved Approved Vesicles,Cytosol NA NA 210000 "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol Vesicles "HPA052488: AB_2681849, HPA074588: " "unprognostic (4.13e-2)" "unprognostic (1.66e-1)" "prognostic favorable (2.10e-5)" "unprognostic (1.64e-1)" "unprognostic (2.05e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (7.94e-4)" "unprognostic (2.38e-1)" "unprognostic (2.31e-1)" "unprognostic (1.74e-1)" "unprognostic (1.41e-3)" "unprognostic (1.65e-1)" "prognostic favorable (3.06e-5)" "unprognostic (3.47e-1)" "unprognostic (1.19e-1)" "unprognostic (6.61e-3)" "unprognostic (3.13e-2)" 60.8 57.5 22.3 49.5 24.7 76.3 46.0 24.4 33.3 42.0 27.4 56.0 33.8 34.5 46.6 67.9 30.1 35.2 53.4 23.9 24.5 53.6 76.3 47.7 55.4 25.0 23.1 33.3 62.2 62.7 27.5 50.0 26.2 47.8 59.6 35.3 41.0 41.8 127.0 43.5 34.3 46.9 25.0 40.2 49.8 68.7 23.1 56.3 57.7 97.8 82.0 85.7 39.6 29.3 220.1 212.9 116.1 161.0 164.2 169.3 167.5 238.0 245.9 187.1 185.4 153.1 197.8 295.7 303.9 207.5 130.1 164.3 297.8 220.3 312.9 142.4 153.6 202.0 163.1 325.5 137.9 258.7 103.5 133.5 170.0 212.0 288.3 122.4 210.4 146.2 331.7 148.7 220.0 211.2 219.8 134.0 232.9 163.0 120.1 256.4 200.5 345.6 184.7 189.3 186.4 99.6 342.0 256.3 144.2 164.3 222.4 122.6 163.3 206.8 129.5 151.5 190.3 146.6 233.2 253.8 145.4 258.1 128.5 1.4 5.8 7.7 6.3 11.1 8.8 7.9 8.1 7.7 7.0 6.5 8.2 8.1 1.9 7.2 9.9 3.8 10.5 4.3 22.3 24.7 24.4 33.3 23.9 24.5 25.0 23.1 26.2 25.0 23.1 29.3 69.4 76.9 160.2 39.5 92.3 242.2 232.0 47.1 170.8 47.7 95.0 61.6 123.4 57.2 69.1 86.5 50.1 76.1 94.5 88.1 103.7 58.9 94.9 109.0 95.6 74.4 66.6 328.5 61.6 63.4 118.3 77.2 81.1 153.9 24.7 93.2 43.5 77.9 75.2 52.2 47.0 107.2 32.6 60.8 116.3 51.6 47.8 80.9 64.0 35.6 50.1 43.6 25.7 38.7 42.9 73.0 66.9 47.4 166.2 271.0 38.3 120.3 52.7 41.5 59.2 94.6 123.0 138.3 83.5 198.5 257.7 102.1 132.1 128.1 114.1 270.4 GSTM2 GST4 ENSG00000213366 "Glutathione S-transferase mu 2" P28161 1 109668022-109709551 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 61.0;Plasma cells: 28.4;Squamous epithelial cells: 27.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 116.0;HSkMC: 115.6" "Low region specificity" "Detected in all" "CAB040547, HPA055972, HPA055973" Approved Supported Vesicles,Cytosol NA NA 1200000 "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" Cytosol Vesicles "CAB040547: , HPA055972: AB_2682992, HPA055973: AB_2682993" "unprognostic (2.51e-3)" "unprognostic (1.28e-1)" "unprognostic (2.04e-2)" "unprognostic (2.57e-2)" "unprognostic (2.20e-1)" "unprognostic (5.04e-2)" "unprognostic (7.31e-2)" "prognostic favorable (9.70e-5)" "unprognostic (1.51e-2)" "unprognostic (7.43e-2)" "unprognostic (1.80e-3)" "unprognostic (2.94e-1)" "unprognostic (1.48e-3)" "unprognostic (1.07e-2)" "unprognostic (1.87e-1)" "unprognostic (2.32e-1)" "unprognostic (2.14e-1)" 73.7 84.4 92.3 11.9 109.9 10.7 81.2 86.7 104.6 165.9 111.5 115.2 26.3 70.6 43.7 61.6 102.7 22.0 99.7 93.5 104.7 86.8 35.6 45.2 14.3 94.3 97.1 240.9 54.5 53.6 113.7 9.3 91.9 159.0 17.7 25.1 55.2 80.7 218.4 88.2 65.5 34.2 93.9 52.6 88.3 41.9 105.2 15.9 97.9 108.4 12.6 108.3 144.5 90.6 0.0 3.5 37.8 38.9 44.0 116.0 7.2 24.5 42.6 22.1 28.0 6.7 0.0 0.7 25.5 61.1 18.0 0.2 3.1 0.2 28.6 1.5 0.8 14.0 0.4 9.3 29.6 1.1 25.2 115.6 1.0 32.7 0.0 58.5 16.1 11.6 4.2 0.7 48.5 0.3 19.5 24.6 6.7 0.7 32.4 23.8 0.1 0.2 6.6 0.5 8.1 18.7 0.0 1.0 13.0 21.7 38.6 7.0 0.2 24.3 1.2 35.3 1.9 11.9 19.0 1.3 36.7 0.5 0.3 1.8 3.8 29.6 3.1 6.3 3.1 8.8 8.8 3.4 23.0 6.2 34.4 15.1 2.2 18.0 4.1 29.8 9.4 10.8 92.3 109.9 86.7 104.6 93.5 104.7 94.3 97.1 91.9 93.9 105.2 90.6 2.0 0.0 4.8 16.0 4.5 4.8 2.4 0.9 20.5 1.5 4.5 4.3 61.0 2.8 11.5 3.7 0.0 0.5 6.1 0.4 0.0 0.2 1.9 2.8 10.3 5.8 0.0 10.9 1.5 0.0 0.2 19.2 14.8 2.7 2.5 4.4 1.8 0.8 1.5 3.3 2.6 1.3 2.0 0.8 2.3 10.4 15.5 3.4 5.4 11.2 0.7 7.2 8.2 12.5 0.7 0.1 0.0 10.5 28.4 0.8 0.4 1.2 9.9 0.3 6.6 5.6 13.6 0.3 0.8 27.0 2.8 0.5 5.1 4.0 0.7 1.6 GTF2F1 "BTF4, RAP74, TF2F1, TFIIF" ENSG00000125651 "General transcription factor IIF subunit 1" P35269 19 6379572-6393981 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 228.3;Late spermatids: 391.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022793, HPA028707, HPA070752" Supported Enhanced "Nucleoplasm,Vesicles,Cell Junctions" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 16: U-266 - Nucleosome" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Vesicles, Cell Junctions" "HPA022793: AB_1857946, HPA028707: AB_2672745, HPA070752: AB_2732163" "unprognostic (1.30e-2)" "unprognostic (6.05e-3)" "unprognostic (2.00e-1)" "prognostic favorable (8.39e-4)" "unprognostic (3.18e-1)" "unprognostic (8.46e-2)" "unprognostic (1.05e-1)" "unprognostic (1.38e-1)" "unprognostic (1.23e-1)" "unprognostic (5.99e-2)" "unprognostic (6.45e-3)" "unprognostic (6.96e-2)" "prognostic favorable (9.80e-4)" "unprognostic (1.34e-2)" "unprognostic (7.02e-2)" "unprognostic (9.92e-2)" "unprognostic (4.25e-1)" 35.0 38.1 36.7 34.0 38.4 71.0 34.2 43.6 43.0 48.8 30.2 41.2 40.5 48.5 25.9 46.0 44.8 36.1 32.8 39.1 35.8 37.6 30.0 31.5 43.5 34.4 34.3 73.6 57.5 42.6 49.8 26.8 34.6 39.5 23.3 24.9 43.8 31.7 36.8 36.8 39.2 25.1 30.1 36.4 43.9 68.3 36.1 37.1 49.6 22.6 29.8 37.3 41.0 36.1 115.6 97.1 62.0 100.9 46.5 73.1 47.3 81.7 84.7 112.0 106.0 104.4 48.5 76.3 111.9 67.2 73.5 109.9 69.3 65.6 57.1 106.6 90.1 97.2 60.7 86.9 78.6 107.1 79.5 82.8 78.2 85.5 64.1 86.4 69.0 72.9 115.9 91.7 63.9 96.2 115.4 79.7 108.2 59.7 124.3 101.5 68.0 94.6 67.5 74.2 76.1 99.8 83.0 64.5 95.6 36.4 84.0 94.0 79.8 78.5 62.6 134.0 110.1 153.9 197.2 79.7 98.1 124.9 91.0 10.2 29.7 20.8 26.1 28.4 29.7 32.9 23.5 24.9 23.3 31.6 27.0 24.6 40.1 27.6 30.2 30.3 25.4 19.8 36.7 38.4 43.6 43.0 39.1 35.8 34.4 34.3 34.6 30.1 36.1 36.1 29.2 48.1 56.6 5.2 51.9 24.3 50.2 40.5 53.5 27.6 43.1 34.7 28.9 32.9 58.4 25.8 8.4 46.1 51.6 88.2 21.5 48.5 228.3 70.5 70.7 41.0 30.5 51.7 6.9 50.8 43.0 43.3 51.0 57.4 63.8 32.7 58.9 26.0 60.2 25.2 7.0 53.4 24.4 54.8 25.9 391.6 44.4 42.1 33.8 5.6 66.0 35.6 49.4 3.5 4.9 47.4 66.0 49.7 55.4 29.9 65.3 48.8 83.6 33.5 32.9 44.8 52.9 71.8 38.3 44.9 21.0 54.0 48.3 41.8 54.4 40.6 GTPBP2 ENSG00000172432 "GTP binding protein 2" Q9BX10 6 43605316-43629264 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 5.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 5.4" "Cell line enhanced" "Detected in all" "hTERT-HME1: 181.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031418, HPA031419" Approved Approved Vesicles NA Yes "Cluster 34: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA031418: AB_2673872, HPA031419: AB_10600709" "unprognostic (1.35e-1)" "unprognostic (1.01e-1)" "unprognostic (8.94e-2)" "unprognostic (1.08e-3)" "unprognostic (2.56e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (1.08e-6)" "unprognostic (4.71e-2)" "unprognostic (2.58e-3)" "unprognostic (6.47e-2)" "unprognostic (8.31e-2)" "unprognostic (6.15e-3)" "prognostic unfavorable (1.44e-15)" "unprognostic (1.13e-1)" "unprognostic (3.36e-1)" "unprognostic (1.06e-1)" "unprognostic (2.89e-3)" 38.5 29.8 14.5 15.3 15.3 28.7 37.4 16.5 17.9 39.5 16.0 34.0 19.9 26.8 15.5 61.3 25.1 12.5 35.4 14.4 15.0 36.1 33.3 46.7 16.9 17.5 16.7 29.0 40.0 24.1 40.0 18.0 15.6 31.5 17.0 18.9 42.6 11.6 31.6 26.5 34.7 15.4 14.3 44.5 35.9 27.2 17.0 16.8 44.2 10.4 17.0 33.9 40.4 16.2 59.2 10.9 37.7 24.0 28.3 30.6 45.6 56.3 55.2 52.6 70.1 12.0 19.9 18.8 23.5 26.9 53.8 31.6 9.8 14.5 45.6 60.9 31.6 44.1 33.0 13.9 126.0 35.6 50.1 35.1 160.5 72.5 181.4 35.1 20.5 25.7 77.1 107.8 26.2 13.9 23.4 45.1 10.6 41.2 14.8 19.4 29.5 17.5 24.0 25.8 33.1 32.4 19.5 14.0 72.5 19.0 30.3 37.3 34.8 27.2 33.2 20.5 38.3 70.8 38.2 26.7 45.4 26.0 27.5 5.4 0.8 2.1 1.2 0.7 0.9 0.6 0.2 1.1 0.4 1.0 0.7 1.0 1.3 0.6 0.9 1.1 0.6 1.2 14.5 15.3 16.5 17.9 14.4 15.0 17.5 16.7 15.6 14.3 17.0 16.2 19.6 3.2 5.5 6.8 5.1 5.2 2.3 4.3 1.2 5.9 7.5 5.0 11.4 5.7 5.7 1.8 8.4 2.8 5.3 24.0 0.0 10.1 17.0 8.5 8.2 9.7 1.2 14.3 7.2 10.1 9.8 6.8 11.7 13.3 1.3 5.7 6.8 5.5 8.2 1.7 6.3 8.8 2.0 12.6 6.5 47.6 5.3 16.0 7.2 5.6 10.1 3.4 1.0 5.5 9.1 20.7 13.4 4.1 2.4 5.8 6.8 1.8 4.1 9.2 13.1 5.3 7.8 7.1 8.1 4.4 5.3 2.5 3.8 4.7 6.0 12.6 GUCY2C "GUC2C, STAR" ENSG00000070019 "Guanylate cyclase 2C" P25092 12 14612632-14696599 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis" "Lyase, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "intestine: 68.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 34.4;Enteroendocrine cells: 176.7;Intestinal goblet cells: 56.0;Paneth cells: 97.9;Proximal enterocytes: 81.5;Undifferentiated cells: 47.6" "Group enriched" "Detected in many" 5 "colorectal cancer: 23.9;stomach cancer: 9.1" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AN3-CA: 1.4;CACO-2: 1.1;CAPAN-2: 1.7;SiHa: 1.6" "Region enhanced" "Detected in some" "midbrain: 1.8" "Low region specificity" "Detected in all" "HPA037655, HPA073759" Uncertain Uncertain Vesicles NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "HPA037655: AB_10672388, HPA073759: " "unprognostic (1.08e-1)" "unprognostic (2.12e-1)" "unprognostic (3.58e-2)" "unprognostic (2.11e-2)" "unprognostic (1.60e-2)" "unprognostic (5.67e-3)" "prognostic unfavorable (1.37e-5)" "unprognostic (9.14e-2)" "unprognostic (1.49e-2)" "unprognostic (2.95e-1)" "unprognostic (1.58e-1)" "unprognostic (5.40e-2)" "unprognostic (2.35e-4)" "unprognostic (8.02e-2)" "unprognostic (1.64e-1)" "unprognostic (1.33e-1)" "unprognostic (1.98e-1)" 0.5 0.2 0.1 3.4 0.3 0.5 0.0 0.2 0.1 0.0 3.0 37.2 68.2 0.3 0.0 1.9 0.0 0.9 2.2 0.2 0.3 0.4 0.3 0.2 0.4 0.4 0.3 0.0 2.2 0.0 0.0 0.2 0.4 0.3 41.4 0.1 0.6 0.0 0.7 1.0 66.5 1.4 0.5 0.2 1.9 0.4 0.3 0.0 0.5 0.0 0.3 0.5 0.2 0.5 0.4 0.0 0.0 1.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.1 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.2 1.6 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.3 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 1.5 0.0 0.0 0.3 1.1 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.2 0.1 0.3 0.2 0.1 0.2 0.3 0.4 0.3 0.4 0.5 0.3 0.5 0.0 0.0 0.0 1.3 6.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 34.4 0.0 0.0 0.1 0.1 0.0 0.0 176.7 0.0 1.4 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 56.0 0.0 0.3 0.3 0.2 0.0 0.3 0.0 1.0 0.3 0.0 0.0 1.0 0.2 0.4 97.9 0.0 0.1 0.0 81.5 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 47.6 0.0 GULP1 "CED-6, CED6, GULP" ENSG00000144366 "GULP PTB domain containing engulfment adaptor 1" Q9UBP9 2 188291669-188595931 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Lipid transport, Phagocytosis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 83.0" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 136.5;Inhibitory neurons: 115.5;Muller glia cells: 129.4;Syncytiotrophoblasts: 204.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 106.9;SH-SY5Y: 83.4;WM-115: 228.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020587 Enhanced Approved Vesicles NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA020587: AB_1850452" "unprognostic (1.95e-1)" "unprognostic (3.32e-1)" "unprognostic (3.80e-2)" "unprognostic (5.19e-2)" "unprognostic (2.12e-2)" "unprognostic (2.41e-1)" "unprognostic (8.69e-4)" "unprognostic (3.86e-2)" "unprognostic (1.06e-1)" "unprognostic (9.28e-2)" "unprognostic (8.25e-3)" "unprognostic (2.23e-1)" "prognostic favorable (4.25e-6)" "prognostic unfavorable (6.17e-4)" "unprognostic (1.29e-1)" "unprognostic (7.33e-2)" "unprognostic (3.04e-4)" 9.4 24.5 2.0 5.8 6.4 0.2 13.1 0.0 4.3 27.7 33.0 13.3 13.5 35.3 83.0 19.2 18.2 17.5 5.2 3.6 7.3 21.3 0.8 13.3 1.7 22.7 4.1 31.8 22.2 26.1 3.4 19.7 23.2 27.7 7.8 17.7 16.1 28.1 9.6 6.2 15.8 21.7 0.3 5.9 22.6 28.0 4.0 1.7 7.8 16.7 3.3 11.9 14.3 0.1 12.5 26.9 106.9 23.8 17.1 15.5 18.6 16.5 27.0 25.1 19.9 18.9 62.6 0.0 13.2 13.2 28.2 8.3 20.0 1.5 18.9 0.0 13.9 27.0 20.5 0.2 15.1 0.0 0.2 10.1 4.2 13.0 14.2 42.9 12.7 0.0 22.5 0.5 19.3 1.8 0.0 0.4 27.4 18.1 46.0 0.1 25.1 14.0 60.0 4.7 0.5 83.4 0.0 14.6 40.2 47.9 4.7 0.1 5.9 7.8 3.8 26.3 9.6 0.0 0.1 0.0 4.6 0.0 228.6 0.2 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 2.0 6.4 0.0 4.3 3.6 7.3 22.7 4.1 23.2 0.3 4.0 0.1 22.8 16.0 13.4 43.4 1.6 15.7 23.9 3.6 10.2 1.5 10.6 12.2 1.6 45.8 28.2 23.9 0.0 41.1 0.6 3.7 45.0 33.0 5.0 23.9 35.4 32.1 136.5 0.0 82.7 38.2 5.9 55.3 39.8 52.1 0.0 2.2 10.0 1.5 3.2 1.7 115.5 4.6 14.2 1.0 10.5 7.9 20.5 2.0 35.6 53.4 1.1 129.4 0.0 3.0 3.1 51.3 9.8 61.3 1.4 79.8 30.8 43.2 43.5 3.7 6.6 42.2 27.9 79.6 23.9 38.9 27.6 204.4 2.7 27.0 4.7 34.5 GUSB ENSG00000169919 "Glucuronidase beta" P08236 7 65960684-65982215 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Cancer-related genes, Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 213.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036322, HPA036323" Approved Supported Vesicles "Intracellular and membrane" NA NA 330000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA036322: AB_10670796, HPA036323: AB_2675059" "unprognostic (1.54e-2)" "unprognostic (6.49e-2)" "unprognostic (1.18e-2)" "unprognostic (3.50e-1)" "unprognostic (2.58e-2)" "unprognostic (4.46e-2)" "unprognostic (2.89e-1)" "unprognostic (1.56e-3)" "unprognostic (1.32e-1)" "unprognostic (2.32e-1)" "unprognostic (7.00e-3)" "unprognostic (1.91e-1)" "unprognostic (3.34e-2)" "unprognostic (8.83e-3)" "unprognostic (1.98e-1)" "unprognostic (5.06e-1)" "unprognostic (1.45e-1)" 28.4 18.2 11.0 22.3 12.3 84.2 80.9 12.0 16.1 26.7 14.3 38.2 36.1 26.2 41.8 16.4 24.6 27.6 19.6 10.7 11.5 25.1 104.0 35.7 25.6 13.2 12.2 19.9 33.6 30.3 12.6 48.2 13.2 20.2 41.9 9.7 32.9 21.2 10.9 18.8 29.8 19.1 11.9 34.0 38.1 19.5 13.0 22.7 27.7 14.4 24.0 27.3 15.4 13.5 67.0 26.5 25.2 56.3 80.9 49.1 35.3 21.3 56.8 45.0 42.1 37.0 67.8 30.9 32.3 26.8 24.1 27.5 16.5 25.1 26.8 27.3 34.1 41.5 40.9 27.3 39.7 89.6 67.1 33.4 26.7 26.3 33.3 54.5 39.3 18.0 63.2 213.5 30.5 50.3 34.2 92.0 17.9 103.0 21.0 34.4 55.9 172.4 29.4 42.8 36.2 32.7 55.6 129.1 72.3 29.9 71.1 88.8 28.5 55.3 49.3 21.8 53.6 119.6 151.9 50.0 41.0 116.3 68.3 26.0 80.1 65.7 32.0 103.0 28.4 27.7 24.7 28.4 80.5 22.6 16.8 19.5 13.2 46.6 93.5 34.2 34.5 51.4 11.0 12.3 12.0 16.1 10.7 11.5 13.2 12.2 13.2 11.9 13.0 13.5 53.1 51.3 58.7 10.1 33.0 18.0 32.0 51.9 29.0 12.2 26.1 19.9 12.2 48.6 48.9 29.5 8.4 81.9 32.6 52.2 5.9 41.1 59.1 28.9 26.5 39.7 43.0 47.1 12.3 30.3 61.2 49.5 49.5 49.4 36.8 38.3 37.9 72.7 126.4 16.8 10.6 51.6 30.5 88.1 33.2 46.7 43.2 78.0 39.2 14.0 44.8 28.0 20.6 8.5 14.2 29.4 49.5 28.6 87.5 25.3 50.6 26.8 43.2 20.1 26.3 27.1 26.0 49.6 31.0 16.0 14.8 66.9 32.2 24.4 44.3 29.6 GYG1 GYG ENSG00000163754 "Glycogenin 1" P46976 3 148991408-149031775 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycogen biosynthesis" Transferase "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 560.0;tongue: 357.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 229.8;Early spermatids: 251.2;Late spermatids: 368.8;Spermatocytes: 296.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030497, HPA073229" Supported Approved Vesicles NA NA 30000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA030497: AB_10602326, HPA073229: " "unprognostic (2.68e-2)" "unprognostic (6.31e-3)" "unprognostic (3.21e-1)" "unprognostic (1.81e-1)" "unprognostic (6.19e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (6.15e-5)" "unprognostic (2.55e-2)" "unprognostic (2.71e-1)" "unprognostic (1.10e-1)" "unprognostic (7.75e-3)" "unprognostic (1.29e-1)" "unprognostic (3.56e-2)" "unprognostic (1.27e-2)" "unprognostic (1.96e-1)" "unprognostic (1.05e-1)" "unprognostic (4.79e-2)" 40.3 31.1 30.1 31.3 32.2 219.8 33.8 33.1 39.4 36.5 28.7 152.2 16.7 64.1 38.7 53.6 52.6 23.9 117.8 29.9 44.0 29.0 18.6 41.1 24.8 37.0 39.7 43.8 42.7 25.2 31.5 23.0 39.0 47.3 25.6 34.3 39.7 64.4 560.0 21.2 37.7 68.1 35.9 59.2 50.7 115.1 33.6 18.0 21.1 357.6 23.0 86.1 30.8 38.3 62.7 39.8 29.0 32.6 78.5 81.7 39.5 90.2 74.4 128.3 119.2 52.3 62.2 0.1 43.5 105.1 68.4 18.8 76.7 39.8 128.6 21.1 33.3 47.6 16.7 59.9 70.7 49.1 68.8 45.1 63.8 42.7 53.3 66.8 74.7 30.7 29.8 109.8 74.7 110.3 9.6 38.9 34.9 48.3 32.2 26.7 43.8 89.3 35.7 57.6 23.7 11.3 47.6 64.6 54.4 27.3 64.4 51.4 62.9 65.4 19.4 47.4 66.9 98.7 59.1 44.4 55.1 74.3 21.7 22.7 58.1 42.4 39.4 59.6 73.1 15.9 25.7 41.3 64.0 14.0 13.8 23.5 27.0 44.3 67.9 25.3 39.4 50.1 30.1 32.2 33.1 39.4 29.9 44.0 37.0 39.7 39.0 35.9 33.6 38.3 27.7 12.8 11.1 16.3 28.3 12.1 22.4 27.7 12.5 9.4 22.5 17.1 229.8 15.7 21.9 33.1 18.8 36.5 50.4 9.9 27.4 43.4 251.2 7.9 15.2 32.6 14.4 12.2 9.8 77.6 47.2 45.0 17.3 9.5 18.3 19.7 45.3 13.5 95.3 6.7 11.3 19.0 26.4 87.1 26.3 368.8 53.1 56.2 40.9 6.5 56.2 132.1 36.0 11.6 5.4 31.6 14.3 76.8 104.1 45.9 15.0 17.3 16.1 7.0 65.7 35.8 50.3 296.7 52.2 23.1 14.9 29.3 61.2 33.8 15.2 19.6 HACL1 "2-HPCL, HPCL, PHYH2" ENSG00000131373 "2-hydroxyacyl-CoA lyase 1" Q9UJ83 3 15560699-15601852 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 117.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 117.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035496, HPA035497, HPA073760" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles Nucleoplasm "HPA035496: AB_10601328, HPA035497: AB_2674653, HPA073760: AB_2686633" "unprognostic (6.64e-3)" "unprognostic (2.82e-2)" "unprognostic (2.24e-3)" "unprognostic (3.82e-1)" "unprognostic (4.08e-2)" "unprognostic (1.77e-1)" "unprognostic (2.96e-2)" "unprognostic (6.31e-2)" "unprognostic (8.27e-3)" "unprognostic (5.23e-2)" "unprognostic (3.30e-2)" "unprognostic (1.44e-1)" "prognostic favorable (2.63e-5)" "unprognostic (6.62e-2)" "unprognostic (2.66e-1)" "unprognostic (3.23e-2)" "unprognostic (9.07e-2)" 14.4 12.0 7.5 8.2 7.8 11.6 14.6 10.4 10.5 9.1 7.9 10.0 56.6 8.3 16.6 7.5 10.8 8.8 11.0 7.6 7.0 26.0 51.8 9.7 14.1 7.4 7.2 7.5 15.2 20.0 7.8 7.8 7.0 10.8 12.0 12.2 9.1 9.1 17.6 10.6 27.7 9.5 7.4 11.4 13.2 26.7 6.8 13.9 20.4 10.6 14.5 10.3 6.4 10.0 15.1 28.6 8.2 30.7 13.4 12.4 82.3 14.2 22.0 26.6 26.3 27.3 14.3 14.6 9.7 18.7 10.5 10.4 18.7 25.3 23.8 13.6 36.4 25.4 17.7 24.7 20.3 30.5 23.1 13.7 16.2 37.9 16.6 8.3 31.4 18.3 24.0 21.2 22.9 28.7 14.0 12.6 19.7 19.7 29.7 14.4 21.5 19.6 26.4 20.2 9.6 12.3 22.4 19.0 25.2 12.8 8.5 25.4 22.5 14.1 14.6 17.4 24.7 27.2 50.9 28.5 27.1 26.4 17.2 117.3 16.0 18.3 14.4 20.1 21.2 15.4 15.5 18.0 16.0 21.2 14.8 16.1 3.4 24.1 24.2 10.2 19.8 13.0 7.5 7.8 10.4 10.5 7.6 7.0 7.4 7.2 7.0 7.4 6.8 10.0 12.4 9.6 17.3 34.9 22.1 10.3 12.0 13.5 20.5 19.3 9.1 10.2 6.4 14.3 15.6 11.0 29.2 27.2 15.7 6.1 13.7 16.0 66.6 12.6 6.0 12.3 9.1 8.2 67.4 25.2 18.0 12.0 11.2 5.4 13.3 12.7 8.9 24.3 13.2 13.5 55.8 7.5 10.2 9.3 8.1 56.8 23.3 8.8 12.4 25.3 19.3 24.8 8.2 40.7 38.8 14.5 11.2 15.4 21.4 9.0 41.9 39.7 29.8 38.3 6.6 9.0 11.2 51.1 24.4 8.6 7.1 18.9 19.4 15.1 10.6 7.9 HAND2 "bHLHa26, dHand, Hed, Thing2" ENSG00000164107 "Heart and neural crest derivatives expressed 2" P61296 4 173524969-173530229 "Predicted intracellular proteins, Transcription factors" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 60.5" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 100.3;Endometrial stromal cells: 317.1" "Cancer enhanced" "Detected in many" "pancreatic cancer: 5.5;stomach cancer: 4.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 24 "SH-SY5Y: 410.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA019591, CAB025576" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm Vesicles "CAB025576: , HPA019591: AB_2670199" "unprognostic (4.11e-2)" "unprognostic (7.50e-3)" "unprognostic (2.43e-2)" "unprognostic (1.25e-2)" "unprognostic (1.95e-1)" "unprognostic (2.44e-2)" "unprognostic (1.82e-1)" "unprognostic (2.24e-1)" "unprognostic (1.28e-2)" "unprognostic (2.56e-1)" "unprognostic (2.44e-1)" "unprognostic (1.35e-1)" "unprognostic (3.27e-2)" "unprognostic (4.95e-2)" "unprognostic (1.56e-1)" "unprognostic (6.39e-3)" 4.9 28.0 0.0 5.4 0.0 0.0 2.1 0.5 0.0 22.2 0.0 60.5 2.5 33.4 0.3 1.0 16.0 16.2 36.8 0.0 0.0 0.1 5.5 0.0 0.2 0.0 0.0 15.3 4.1 0.0 0.1 20.9 0.2 1.3 4.4 0.0 0.8 1.0 0.2 1.5 11.0 27.3 0.0 1.1 22.1 0.4 0.0 0.4 1.5 1.1 0.8 12.4 5.3 0.0 0.0 0.1 0.0 0.0 16.6 7.7 0.3 2.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.5 0.0 0.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 17.3 0.0 0.1 1.7 0.0 3.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 410.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 1.3 4.1 0.0 0.0 0.0 0.0 0.2 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.4 0.1 0.0 1.2 0.0 0.1 0.1 100.3 2.8 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.6 0.2 9.0 317.1 2.7 0.0 0.0 0.0 0.4 1.4 30.4 0.0 5.3 0.0 0.0 6.8 0.1 2.5 0.0 0.0 0.0 0.0 0.0 2.3 0.9 39.4 1.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 10.9 0.1 0.3 0.2 0.3 2.3 1.3 0.6 0.0 0.0 HAO2 "GIG16, HAOX2" ENSG00000116882 "Hydroxyacid oxidase 2" Q9NYQ3 1 119368779-119394130 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "kidney: 303.7;liver: 425.6" "Group enriched" "Detected in some" 7 "Hepatocytes: 256.8;Proximal tubular cells: 450.1" "Group enriched" "Detected in some" 26 "liver cancer: 25.6;renal cancer: 11.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050355 Uncertain Vesicles,Cytosol NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Vesicles "HPA050355: " "unprognostic (1.13e-1)" "unprognostic (1.68e-2)" "unprognostic (2.07e-1)" "unprognostic (1.00e-1)" "unprognostic (6.22e-2)" "unprognostic (5.33e-3)" "unprognostic (2.80e-2)" "unprognostic (3.27e-1)" "unprognostic (3.15e-1)" "unprognostic (3.17e-1)" "unprognostic (1.41e-1)" "unprognostic (1.73e-1)" "prognostic favorable (4.92e-4)" "unprognostic (9.66e-2)" "unprognostic (1.79e-1)" "unprognostic (2.89e-2)" "unprognostic (5.14e-4)" 0.0 0.6 0.2 0.1 0.6 0.0 0.6 0.1 0.6 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 303.7 425.6 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 4.4 0.1 0.0 0.1 0.4 0.2 0.1 0.3 23.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.1 0.6 0.2 0.0 0.2 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 5.7 0.0 11.0 0.0 0.0 0.0 0.0 49.0 0.0 0.0 0.0 0.0 0.6 0.0 13.5 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 4.2 256.8 0.1 0.0 0.1 0.0 0.0 6.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 450.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 HAPLN1 CRTL1 ENSG00000145681 "Hyaluronan and proteoglycan link protein 1" P10915 5 83637805-83720855 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "placenta: 75.0" "Cell type enhanced" "Detected in some" "Fibroblasts: 146.7;Granulosa cells: 43.2;Inhibitory neurons: 35.6;Syncytiotrophoblasts: 23.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 33 "PC-3: 152.4;SuSa: 70.1;TIME: 91.8;U-2 OS: 139.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019105, HPA019482, HPA025238" Enhanced Approved Supported Vesicles "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA019105: AB_1850496, HPA019482: AB_1850498, HPA025238: " "unprognostic (5.74e-4)" "unprognostic (2.94e-2)" "unprognostic (6.58e-3)" "unprognostic (2.30e-2)" "unprognostic (1.30e-1)" "unprognostic (2.76e-3)" "unprognostic (6.01e-4)" "unprognostic (2.52e-2)" "unprognostic (1.70e-1)" "unprognostic (9.04e-3)" "unprognostic (1.31e-1)" "unprognostic (2.28e-2)" "prognostic unfavorable (4.81e-9)" "unprognostic (6.87e-2)" "unprognostic (2.04e-1)" "unprognostic (8.62e-2)" "unprognostic (3.91e-2)" 0.1 0.0 0.3 0.8 0.7 0.0 0.1 1.1 0.9 0.1 0.0 9.0 7.2 0.6 0.3 2.1 0.0 0.8 3.9 0.6 2.7 0.1 0.0 0.5 0.0 0.9 1.0 0.5 0.5 0.2 0.0 75.0 0.6 0.9 11.1 0.1 0.5 0.0 0.0 0.3 10.8 0.5 0.3 0.2 4.8 0.0 0.0 0.0 0.2 0.0 0.0 2.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 2.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.2 0.0 3.4 0.0 152.4 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.3 0.0 70.1 0.1 0.0 91.8 0.0 139.4 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 1.1 0.9 0.6 2.7 0.9 1.0 0.6 0.3 0.0 0.3 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 9.2 0.0 0.2 0.0 0.0 0.0 0.1 0.5 6.9 0.0 0.0 0.5 0.0 10.6 146.7 0.0 0.1 0.0 43.2 0.0 0.0 10.6 0.0 35.6 2.6 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.6 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 23.7 0.1 3.8 0.4 0.0 HAVCR1 "CD365, HAVCR, HAVCR-1, KIM1, TIM-1, TIM1, TIMD1" ENSG00000113249 "Hepatitis A virus cellular receptor 1" Q96D42 5 157029413-157059119 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 4.6;kidney: 7.5" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.9;Inhibitory neurons: 1.3;Microglial cells: 5.6;Oligodendrocytes: 1.8;Proximal tubular cells: 2.3" "Cancer enriched" "Detected in many" 12 "renal cancer: 26.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A549: 93.0;CACO-2: 113.9;RPTEC TERT1: 43.5" "Low region specificity" "Detected in many" "HPA007173, CAB075697" Uncertain Approved Vesicles NA NA 155000 "Cluster 15: NK-cells - Transcription" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "CAB075697: , HPA007173: AB_1080282" "unprognostic (1.24e-1)" "unprognostic (1.66e-1)" "unprognostic (5.76e-2)" "unprognostic (2.00e-1)" "unprognostic (6.99e-2)" "unprognostic (2.46e-3)" "unprognostic (4.75e-3)" "unprognostic (3.20e-2)" "unprognostic (3.21e-1)" "unprognostic (8.70e-4)" "unprognostic (3.81e-3)" "unprognostic (7.10e-3)" "prognostic unfavorable (7.81e-4)" "unprognostic (1.38e-1)" "unprognostic (1.57e-1)" "prognostic favorable (1.32e-4)" 0.3 0.0 0.3 0.4 0.3 0.9 0.1 0.6 0.4 0.1 0.5 4.6 0.2 0.1 0.2 0.0 0.1 0.5 0.0 0.4 0.3 7.5 0.3 0.3 0.6 0.7 0.4 0.1 0.0 0.1 0.0 0.1 0.5 0.0 3.5 0.3 0.1 0.0 0.0 0.2 0.1 0.2 0.3 0.3 0.3 0.9 0.5 0.1 0.1 0.0 0.3 0.1 0.0 0.8 0.0 93.0 0.2 0.0 0.3 0.0 13.8 0.0 0.0 0.0 0.0 113.9 0.0 0.0 14.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 4.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 43.5 3.4 0.2 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 5.6 0.1 0.0 0.0 0.0 0.5 0.2 0.1 0.1 0.1 0.2 0.2 0.3 0.1 0.1 0.2 0.6 0.5 0.2 0.4 0.1 0.1 0.6 0.4 0.3 0.3 0.6 0.4 0.4 0.3 0.7 0.4 0.5 0.3 0.5 0.8 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.0 0.2 1.0 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.9 0.0 0.1 0.0 5.6 0.0 0.0 0.0 1.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.2 0.1 0.0 HCK JTK9 ENSG00000101336 "HCK proto-oncogene, Src family tyrosine kinase" P08631 20 32052197-32101856 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Exocytosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Phagocytosis" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 112.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 150.7;Kupffer cells: 155.5;Langerhans cells: 89.2;Macrophages: 170.1;Microglial cells: 52.5;monocytes: 222.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 575.0;eosinophil: 707.8;intermediate monocyte: 1059.1;myeloid DC: 336.3;neutrophil: 801.3;non-classical monocyte: 1251.7" "Group enriched" "Detected in all" 16 "dendritic cells: 336.3;granulocytes: 801.3;monocytes: 1251.7" "Group enriched" "Detected in some" 9 "THP-1: 69.3;U-937: 199.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB005195, HPA035534, HPA063768" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane, Cytosol" "CAB005195: AB_631619, HPA035534: , HPA063768: AB_2685118" "unprognostic (6.22e-2)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "unprognostic (7.98e-2)" "unprognostic (8.83e-2)" "unprognostic (5.50e-2)" "unprognostic (4.09e-2)" "unprognostic (1.72e-2)" "unprognostic (4.34e-2)" "unprognostic (1.59e-1)" "unprognostic (4.08e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (4.92e-2)" "unprognostic (4.42e-2)" "unprognostic (6.95e-2)" "unprognostic (1.12e-1)" 24.8 9.2 4.7 100.0 5.0 55.2 6.0 5.5 6.0 5.5 13.7 12.8 15.2 3.1 2.6 6.7 7.6 14.4 4.8 4.7 6.2 4.7 14.1 46.0 38.6 9.9 6.8 2.5 4.5 2.1 3.1 20.9 8.3 4.0 13.6 0.5 5.1 4.7 1.6 5.8 17.8 25.3 8.1 112.1 6.7 2.3 8.4 14.5 2.8 6.9 39.3 32.8 4.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.9 0.0 0.1 0.1 1.3 0.0 0.0 0.1 0.0 4.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 15.6 0.0 0.1 0.1 4.9 0.4 0.0 0.0 0.4 0.2 0.6 0.0 0.0 0.3 0.0 0.5 0.0 0.2 0.7 0.0 69.3 0.0 0.0 0.3 0.0 0.1 1.9 0.3 10.3 0.0 199.6 0.0 6.4 575.0 707.8 1.1 1059.1 1.3 48.4 1.1 1.1 336.3 43.0 1.1 0.9 801.3 11.0 1251.7 30.4 1.2 566.4 4.7 5.0 5.5 6.0 4.7 6.2 9.9 6.8 8.3 8.1 8.4 12.0 0.6 6.4 14.0 0.0 17.1 3.1 4.0 0.2 0.6 0.1 0.4 1.3 2.0 1.5 3.9 7.3 0.0 0.9 12.1 0.2 1.9 0.1 2.5 0.1 0.1 3.7 1.8 1.7 1.2 0.6 0.9 1.3 4.6 0.1 6.3 0.1 1.1 2.3 150.7 0.0 1.0 0.5 22.4 155.5 89.2 0.3 0.0 170.1 1.8 52.5 222.0 0.0 4.1 1.5 0.6 0.0 0.0 0.0 0.7 0.5 0.1 0.3 1.5 0.1 0.0 0.6 0.5 0.2 0.3 0.2 1.1 1.6 3.0 0.2 0.9 3.7 HCST "DAP10, DKFZP586C1522, KAP10, PIK3AP" ENSG00000126264 "Hematopoietic cell signal transducer" Q9UBK5 19 35902529-35904377 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 253.7;lymphoid tissue: 115.6" "Cell type enhanced" "Detected in many" "dendritic cells: 993.2;Hofbauer cells: 571.1;Kupffer cells: 396.6;Langerhans cells: 584.5;Macrophages: 392.7;NK-cells: 1687.0;T-cells: 769.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 239.9;HL-60: 139.6;HMC-1: 154.3;THP-1: 177.8;U-937: 272.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB034435, HPA063026" Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus, Plasma membrane" Vesicles "CAB034435: AB_2117803, HPA063026: " "unprognostic (1.40e-3)" "unprognostic (3.07e-2)" "unprognostic (3.04e-2)" "unprognostic (7.27e-3)" "unprognostic (1.23e-1)" "unprognostic (8.23e-3)" "unprognostic (1.85e-1)" "unprognostic (2.54e-1)" "prognostic favorable (6.70e-4)" "unprognostic (5.97e-2)" "unprognostic (1.94e-3)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.59e-10)" "unprognostic (3.78e-1)" "unprognostic (3.25e-2)" "unprognostic (1.65e-1)" "unprognostic (1.56e-1)" 27.2 9.5 14.0 53.6 13.8 253.7 14.1 13.7 18.5 9.6 16.6 12.7 11.3 8.3 4.7 5.5 9.9 11.5 8.3 13.5 17.0 10.6 14.5 40.3 68.0 18.3 14.7 5.7 6.7 2.5 9.6 24.7 17.6 9.4 8.6 2.2 10.7 8.2 4.2 6.6 28.2 11.2 17.1 115.6 15.4 3.4 18.2 59.6 7.9 3.0 37.8 16.4 8.0 22.2 0.9 0.0 0.3 0.5 1.1 0.0 0.3 1.9 1.1 0.0 0.6 0.8 1.2 26.9 1.7 2.0 0.4 0.9 0.0 0.2 0.0 0.6 0.0 239.9 0.5 0.7 0.9 139.6 154.3 1.6 0.3 0.0 0.0 0.7 0.0 14.8 2.1 33.4 0.4 0.4 16.9 54.7 0.3 0.3 0.7 0.8 0.5 2.0 0.4 0.1 0.9 0.4 1.3 0.7 0.9 0.2 0.5 177.8 0.5 1.4 1.8 0.2 0.2 1.6 1.1 39.5 1.4 272.2 0.3 124.7 725.8 105.8 1583.4 546.1 1172.3 78.6 664.6 1293.3 409.8 51.0 550.6 1108.0 196.1 1290.7 314.4 823.7 629.9 1421.2 14.0 13.8 13.7 18.5 13.5 17.0 18.3 14.7 17.6 17.1 18.2 22.2 12.3 6.4 43.3 0.0 85.3 28.6 1.3 1.7 2.8 0.4 11.4 12.8 1.2 15.7 7.1 9.2 0.0 3.8 993.2 1.8 0.0 2.8 1.3 4.0 2.5 18.3 0.0 84.2 0.1 1.2 4.7 9.5 14.8 5.5 240.4 0.3 21.0 14.3 571.1 1.7 0.1 0.9 2.0 396.6 584.5 3.0 2.1 392.7 44.4 5.6 309.9 0.7 1687.0 0.0 0.1 1.0 1.4 0.0 97.7 0.6 2.0 6.1 5.1 2.2 19.7 4.2 6.2 2.2 4.9 2.7 21.0 6.0 769.9 1.0 2.7 1.2 HDHD2 DKFZP564D1378 ENSG00000167220 "Haloacid dehalogenase like hydrolase domain containing 2" Q9H0R4 18 47107408-47150500 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040697, CAB045978, HPA059818" Approved Approved Vesicles NA NA 240000 "Cluster 27: Non-specific - Gene expression" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB045978: AB_11124418, HPA040697: AB_2677084, HPA059818: AB_2684132" "unprognostic (3.22e-1)" "unprognostic (6.32e-2)" "unprognostic (9.95e-2)" "unprognostic (7.24e-2)" "unprognostic (1.11e-1)" "unprognostic (1.58e-1)" "unprognostic (3.11e-1)" "unprognostic (1.24e-1)" "unprognostic (2.10e-2)" "unprognostic (5.35e-3)" "unprognostic (1.82e-2)" "unprognostic (8.64e-3)" "prognostic favorable (3.52e-5)" "unprognostic (1.95e-1)" "unprognostic (1.61e-1)" "unprognostic (3.44e-1)" "unprognostic (1.17e-1)" 13.7 26.3 29.1 10.5 31.0 10.5 17.0 37.2 33.4 10.9 27.3 17.2 13.4 11.8 16.0 14.3 16.2 11.9 27.2 28.3 31.5 23.9 30.2 13.5 19.6 34.2 31.8 14.2 17.9 27.0 15.6 11.6 35.2 17.6 16.5 22.1 14.0 17.1 15.5 11.7 13.7 13.5 31.2 13.5 15.8 11.4 31.9 28.1 26.4 24.1 21.2 13.1 10.0 37.5 14.1 9.1 34.5 16.9 20.6 28.4 9.6 15.8 15.3 24.9 25.0 4.7 11.1 23.0 13.4 17.7 11.3 12.2 19.0 21.2 35.3 19.2 17.6 22.1 15.0 23.5 28.2 31.1 19.6 23.4 25.5 14.0 31.3 27.1 21.0 37.2 22.8 26.3 32.6 19.0 29.2 19.6 33.9 11.9 9.3 28.1 22.0 31.2 31.4 21.5 31.2 26.0 15.0 10.6 19.5 23.7 16.0 42.7 15.2 18.9 15.2 5.4 11.5 33.1 16.9 19.9 23.3 32.1 18.8 21.4 24.7 19.7 20.7 22.9 21.8 27.3 21.5 20.5 23.9 26.7 27.1 21.6 2.3 30.5 23.3 15.8 24.2 21.4 29.1 31.0 37.2 33.4 28.3 31.5 34.2 31.8 35.2 31.2 31.9 37.5 8.8 16.0 18.2 21.5 16.9 7.1 11.1 10.7 13.6 22.5 17.7 10.5 13.1 15.7 14.0 11.0 14.6 25.0 9.7 15.6 72.4 18.9 1.9 11.0 8.5 11.5 13.8 13.9 28.9 17.9 15.0 11.0 12.8 6.4 7.6 15.6 13.9 28.1 21.7 45.4 29.2 16.2 14.2 20.3 15.0 2.7 17.7 15.0 16.0 20.6 22.7 53.1 14.4 36.7 45.4 16.4 19.3 23.7 9.7 17.5 16.0 57.7 16.4 27.0 19.7 15.1 19.7 20.2 35.1 13.1 6.0 19.7 12.2 29.8 21.6 13.0 HDHD3 "C9orf158, MGC12904" ENSG00000119431 "Haloacid dehalogenase like hydrolase domain containing 3" Q9BSH5 9 113373419-113376999 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 156.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 214.0;Exocrine glandular cells: 156.4;Paneth cells: 208.6;Proximal enterocytes: 254.0;Proximal tubular cells: 275.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 73.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020427, HPA024158, HPA024585" Enhanced Enhanced Nucleoli,Vesicles NA NA "Cluster 24: B-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoli Vesicles "HPA020427: AB_1850561, HPA024158: AB_1850563, HPA024585: AB_1850565" "unprognostic (1.30e-1)" "prognostic favorable (2.72e-4)" "unprognostic (3.01e-2)" "unprognostic (1.31e-2)" "unprognostic (8.24e-3)" "unprognostic (1.57e-2)" "unprognostic (6.66e-2)" "unprognostic (2.10e-1)" "unprognostic (2.76e-2)" "unprognostic (1.86e-1)" "unprognostic (2.92e-2)" "unprognostic (5.87e-2)" "prognostic favorable (3.54e-7)" "unprognostic (2.16e-2)" "unprognostic (1.84e-1)" "unprognostic (4.68e-1)" "unprognostic (1.19e-3)" 12.2 156.4 16.8 11.1 18.0 8.4 19.5 16.2 19.3 19.9 14.5 59.7 82.9 13.4 14.9 42.1 16.5 17.8 22.4 15.8 17.7 56.3 122.8 10.2 10.2 15.7 17.0 19.9 53.0 68.4 23.1 5.0 16.2 30.4 35.9 8.0 52.2 16.1 8.8 28.3 68.5 7.7 15.7 17.6 50.1 7.0 18.5 6.7 38.7 5.7 7.6 17.6 21.1 15.5 7.4 20.8 4.4 12.3 10.7 4.7 37.0 5.4 10.1 8.6 9.3 38.3 36.1 16.2 6.6 3.0 17.0 28.3 7.0 8.3 2.9 22.9 16.1 22.4 12.5 24.1 12.5 1.4 16.6 7.4 17.4 7.0 19.7 9.9 4.5 14.9 18.0 4.0 4.1 48.3 10.4 6.5 9.9 73.7 16.1 8.5 0.0 13.2 11.0 15.4 11.1 7.0 9.3 39.4 14.0 9.5 24.8 4.7 4.5 1.7 0.1 1.4 1.9 9.7 20.2 6.8 2.1 0.1 1.3 0.2 3.7 8.2 12.4 2.1 14.0 14.8 14.2 11.5 6.1 16.6 14.5 11.1 2.4 8.2 0.2 14.1 17.1 8.5 16.8 18.0 16.2 19.3 15.8 17.7 15.7 17.0 16.2 15.7 18.5 15.5 4.1 9.6 10.1 24.5 19.7 9.9 20.6 26.6 10.8 10.3 38.6 31.2 15.8 80.1 32.6 23.9 10.4 29.4 11.7 214.0 86.1 84.8 0.2 20.9 6.4 9.4 40.3 15.4 9.2 156.4 16.5 8.6 112.7 22.3 7.6 122.4 9.7 85.4 20.6 1.7 10.4 80.4 28.5 6.5 3.7 2.0 14.3 6.9 10.6 6.5 13.7 12.1 15.5 5.5 4.9 104.8 208.6 9.1 9.3 23.7 254.0 275.1 33.3 13.8 6.6 5.5 11.1 0.3 6.0 42.9 14.6 31.6 14.0 26.0 94.6 51.4 HEATR4 MGC48595 ENSG00000187105 "HEAT repeat containing 4" Q86WZ0 14 73478484-73558947 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.4;testis: 11.5" "Cell type enhanced" "Detected in some" "Astrocytes: 27.4;Early spermatids: 85.5;Excitatory neurons: 19.8;Inhibitory neurons: 16.9;Late spermatids: 29.3;Oligodendrocyte precursor cells: 13.0" "Not detected" "Not detected" "Region enriched" "Detected in some" 6 "cerebellum: 6.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 2.2;SCLC-21H: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003642, HPA079348" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 21: Non-specific - Transcription" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles Cytosol "HPA003642: AB_1079376, HPA079348: " "unprognostic (5.25e-2)" "unprognostic (2.45e-3)" "unprognostic (2.85e-2)" "unprognostic (1.36e-2)" "unprognostic (2.53e-2)" "unprognostic (2.60e-2)" "unprognostic (3.50e-1)" "unprognostic (8.09e-2)" "unprognostic (3.13e-1)" "unprognostic (1.51e-1)" "unprognostic (4.49e-2)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (3.28e-1)" "unprognostic (5.50e-2)" "unprognostic (1.96e-1)" "unprognostic (4.82e-3)" 0.5 0.5 0.2 0.8 0.2 0.9 0.4 6.4 1.0 0.7 0.0 0.4 1.9 1.0 0.3 0.6 0.6 0.8 0.6 0.8 0.0 0.4 0.8 0.5 1.6 0.0 0.0 1.0 0.9 0.2 0.5 0.3 0.1 0.4 0.1 2.9 0.8 0.1 1.9 3.6 0.8 0.1 0.0 1.0 0.7 11.5 0.1 0.0 1.0 0.0 0.0 0.3 0.5 0.8 0.7 0.8 0.3 0.5 0.0 0.0 0.3 0.3 0.0 0.0 0.1 0.2 0.2 0.8 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.2 0.1 0.6 0.1 0.0 0.0 0.5 1.0 0.0 0.0 0.1 0.0 0.5 0.0 0.8 0.2 0.2 0.0 2.2 0.2 0.9 0.3 0.2 0.7 0.4 0.4 0.3 0.0 1.1 2.4 0.3 0.8 1.1 1.2 0.5 1.3 0.1 0.4 0.1 0.9 0.7 0.1 0.6 0.2 0.1 0.5 0.2 0.1 0.2 0.1 0.1 0.4 0.1 0.2 0.5 0.5 0.3 0.0 0.6 0.5 0.5 0.3 0.3 0.0 0.2 0.2 0.1 0.2 0.2 6.4 1.0 0.8 0.0 0.0 0.0 0.1 0.0 0.1 0.8 0.2 0.0 1.5 27.4 0.2 0.3 0.5 0.1 0.0 0.8 0.3 0.3 0.8 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 85.5 0.3 0.3 0.4 0.0 0.0 19.8 0.0 0.2 0.5 0.0 0.9 0.0 0.4 0.0 0.6 0.1 0.0 16.9 0.2 0.0 0.0 1.0 29.3 0.6 0.3 0.0 3.7 0.0 0.6 0.0 13.0 6.8 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.0 0.9 0.7 11.1 1.6 0.0 0.9 0.1 0.4 0.1 0.0 0.1 HEATR5B "DKFZp686P15184, KIAA1414" ENSG00000008869 "HEAT repeat containing 5B" Q9P2D3 2 36968383-37084372 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 62.3;Inhibitory neurons: 58.9;Oligodendrocyte precursor cells: 57.3;Oligodendrocytes: 69.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042025, HPA055639" Approved Approved "Nuclear speckles,Vesicles,Cytosol" NA NA 6800 "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Nuclear speckles, Vesicles, Cytosol" "HPA042025: AB_10959880, HPA055639: AB_2682870" "unprognostic (3.11e-2)" "unprognostic (1.65e-2)" "unprognostic (4.07e-1)" "unprognostic (6.05e-2)" "unprognostic (3.70e-2)" "unprognostic (7.75e-2)" "unprognostic (5.95e-2)" "unprognostic (3.33e-3)" "unprognostic (8.26e-2)" "unprognostic (3.08e-2)" "unprognostic (1.66e-1)" "unprognostic (8.07e-2)" "unprognostic (5.80e-3)" "unprognostic (8.69e-2)" "unprognostic (4.18e-1)" "unprognostic (2.72e-1)" "unprognostic (3.95e-1)" 9.7 8.8 7.1 15.0 7.1 24.3 14.5 11.7 9.8 9.9 4.9 9.9 10.8 9.5 16.9 11.7 8.1 10.7 9.7 7.4 6.4 9.3 9.3 10.8 31.9 5.8 5.2 9.8 18.2 13.4 6.3 10.2 6.4 11.4 13.5 24.3 14.3 7.7 4.9 18.2 11.5 8.3 3.9 19.0 12.3 9.6 7.0 24.7 11.8 9.4 31.2 10.1 8.5 8.1 16.2 8.1 11.7 17.8 11.9 11.7 14.9 10.1 7.4 9.0 9.1 9.6 10.9 34.6 7.1 8.6 11.9 13.4 11.6 8.2 11.7 17.0 12.6 22.6 11.3 13.1 7.4 24.5 28.5 10.8 11.2 13.0 12.3 9.9 15.5 18.3 21.6 29.8 10.9 9.6 21.5 17.4 7.7 16.7 5.6 20.5 11.9 26.3 10.5 13.8 14.3 12.6 10.6 16.7 7.8 11.7 12.0 7.9 17.2 13.5 7.7 9.9 7.9 18.5 16.2 39.0 11.0 14.3 9.0 18.3 5.0 12.3 7.7 2.8 7.1 9.7 8.5 8.7 9.0 14.0 8.7 7.6 5.2 7.5 4.4 11.2 9.7 5.9 7.1 7.1 11.7 9.8 7.4 6.4 5.8 5.2 6.4 3.9 7.0 8.1 12.9 22.4 10.3 35.9 20.8 9.8 4.2 4.7 6.8 13.0 11.9 8.3 20.8 8.6 7.1 5.5 10.4 7.0 24.4 11.3 1.9 4.6 6.3 14.8 10.0 9.5 5.4 18.7 62.3 6.2 6.2 9.4 25.5 11.1 7.0 9.8 11.7 7.8 6.3 16.8 58.9 8.9 6.1 17.0 15.7 2.6 9.0 13.2 7.2 56.2 9.2 6.5 16.5 57.3 69.7 8.8 6.3 6.4 17.6 5.5 12.7 5.4 12.8 16.2 19.7 6.5 10.6 3.6 11.2 11.7 11.6 5.6 14.5 7.7 8.7 4.9 HEBP1 "HBP, HEBP" ENSG00000013583 "Heme binding protein 1" Q9NRV9 12 12974870-13000265 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 242.9" "Cell type enriched" "Detected in many" 4 "Proximal enterocytes: 837.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056417, HPA075277" Approved Approved Nucleoplasm,Vesicles NA NA 290000 "Cluster 14: Monocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Vesicles Nucleoplasm "HPA056417: AB_2683122, HPA075277: AB_2686741" "unprognostic (1.65e-1)" "unprognostic (2.31e-2)" "unprognostic (9.28e-2)" "unprognostic (5.67e-3)" "unprognostic (4.45e-3)" "unprognostic (5.42e-3)" "unprognostic (2.70e-1)" "unprognostic (2.44e-1)" "unprognostic (6.04e-2)" "unprognostic (3.50e-2)" "unprognostic (1.94e-3)" "unprognostic (6.19e-2)" "unprognostic (2.28e-3)" "unprognostic (5.71e-2)" "unprognostic (1.64e-1)" "unprognostic (4.02e-2)" "unprognostic (4.43e-2)" 72.5 108.1 43.1 21.0 49.6 57.9 66.6 48.0 46.0 54.8 47.3 44.5 242.9 43.8 17.4 42.6 49.9 41.4 58.5 40.9 46.0 69.1 145.8 54.6 28.2 52.5 46.5 80.0 75.9 50.2 27.8 34.6 49.9 42.4 21.7 15.2 43.7 36.8 39.3 59.6 165.7 38.7 49.9 58.5 45.1 29.8 46.8 19.5 122.6 37.7 21.4 51.2 50.3 53.5 74.2 46.2 29.3 54.8 229.6 167.6 20.5 65.0 91.0 60.2 79.7 29.8 26.6 21.2 25.2 128.8 51.9 64.7 37.6 54.2 69.1 3.0 30.0 12.0 51.0 74.2 159.1 22.3 11.3 134.7 47.9 80.7 101.9 187.0 124.3 25.1 13.6 19.4 103.9 48.1 18.3 34.9 42.5 71.5 30.0 40.2 85.3 22.1 50.8 74.1 16.6 14.8 85.6 41.1 86.5 84.2 21.3 33.6 140.2 45.7 53.1 72.6 36.2 16.4 14.4 7.9 73.2 38.5 18.8 15.6 65.7 17.2 9.6 49.4 13.5 11.5 16.5 10.4 51.2 11.8 20.6 12.1 21.0 18.7 69.8 25.3 9.7 25.9 43.1 49.6 48.0 46.0 40.9 46.0 52.5 46.5 49.9 49.9 46.8 53.5 120.1 54.5 21.3 2.0 14.9 37.5 56.2 38.3 39.9 43.0 73.3 95.8 26.7 115.8 19.8 57.0 4.2 36.2 14.5 56.5 99.7 89.5 33.8 8.6 27.4 80.4 20.4 174.4 1.5 100.3 27.1 68.6 28.5 14.6 1.3 31.6 162.4 121.7 82.0 6.7 1.7 45.3 18.3 85.4 43.1 13.0 89.2 53.7 62.2 0.0 78.1 44.2 10.3 4.5 3.5 71.1 90.5 94.0 8.0 79.8 837.6 93.0 7.0 6.7 52.6 35.7 40.8 13.8 7.5 44.5 36.1 26.3 14.5 84.3 93.6 54.3 HECTD4 "C12orf51, FLJ34154, KIAA0614" ENSG00000173064 "HECT domain E3 ubiquitin protein ligase 4" 12 112160188-112382439 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 141.8;Excitatory neurons: 190.4;Inhibitory neurons: 180.0;Oligodendrocyte precursor cells: 109.1;Oligodendrocytes: 138.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041062, HPA045473" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 71: Testis - DNA repair" "Cluster 15: RT4 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Nucleoplasm "HPA041062: AB_2677281, HPA045473: AB_2679338" "unprognostic (9.27e-2)" "unprognostic (2.35e-1)" "unprognostic (6.50e-2)" "unprognostic (1.33e-1)" "unprognostic (3.38e-1)" "prognostic favorable (2.97e-4)" "unprognostic (3.52e-2)" "unprognostic (2.13e-1)" "unprognostic (2.28e-1)" "unprognostic (1.21e-2)" "unprognostic (4.95e-2)" "unprognostic (1.06e-1)" "unprognostic (2.89e-2)" "unprognostic (2.81e-2)" "unprognostic (1.89e-1)" "unprognostic (1.58e-2)" "unprognostic (4.51e-3)" 6.7 6.5 6.3 3.1 6.1 14.2 6.8 15.6 6.9 10.0 3.4 11.3 2.0 9.5 4.0 11.0 8.4 3.1 6.8 5.9 2.0 7.5 7.6 7.8 3.8 1.0 0.8 8.5 8.8 6.1 11.7 4.1 1.3 10.5 3.6 10.8 7.9 4.0 8.0 10.7 7.6 4.2 0.4 7.6 10.0 6.8 1.2 6.5 13.5 5.6 4.1 8.8 9.7 6.7 5.1 9.2 7.7 6.1 8.7 7.4 3.2 3.2 3.6 4.8 4.0 8.6 1.3 5.2 3.2 6.7 5.4 4.6 10.8 4.3 3.9 7.0 9.4 8.6 10.7 3.8 2.6 6.1 6.3 4.7 4.8 7.3 5.1 8.7 7.7 9.6 10.2 3.9 4.5 4.4 6.7 7.7 3.3 5.7 7.1 8.3 4.2 3.3 2.4 8.8 12.8 8.0 9.2 7.5 2.8 7.2 5.3 6.7 11.0 5.2 4.0 5.7 4.6 11.8 5.7 6.5 4.1 3.3 2.9 0.2 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.2 0.2 0.2 0.3 0.0 0.0 6.3 6.1 15.6 6.9 5.9 2.0 1.0 0.8 1.3 0.4 1.2 6.7 14.7 19.2 20.8 96.9 15.7 11.5 8.4 8.3 18.8 54.3 15.1 11.7 20.1 12.8 9.4 12.9 141.8 10.9 15.2 14.6 0.0 8.0 7.0 23.9 25.9 14.2 27.6 47.4 190.4 8.7 5.2 11.2 23.9 32.2 8.2 17.9 15.7 15.2 6.6 80.8 180.0 14.2 8.2 11.1 6.7 6.3 11.5 12.6 7.2 66.5 11.1 17.7 14.4 109.1 138.8 10.3 9.0 15.8 15.8 12.8 9.2 5.6 16.0 53.8 0.0 19.3 14.6 25.0 7.8 22.1 14.9 8.9 12.9 12.4 14.0 9.0 HEG1 "HEG, KIAA1237" ENSG00000173706 "Heart development protein with EGF like domains 1" Q9ULI3 3 124965710-125055997 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 90.1;Cardiomyocytes: 90.5;Cone photoreceptor cells: 264.8;Endothelial cells: 121.5;Hepatic stellate cells: 130.3;Microglial cells: 92.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 174.1;HHSteC: 241.5;hTERT-RPE1: 351.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010952, HPA011559" Approved Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 510000000 "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Plasma membrane" "HPA010952: AB_2668389, HPA011559: AB_1850580" "unprognostic (1.10e-1)" "unprognostic (2.21e-1)" "unprognostic (6.52e-2)" "unprognostic (2.23e-1)" "unprognostic (1.30e-1)" "unprognostic (5.40e-2)" "unprognostic (6.48e-2)" "unprognostic (2.89e-2)" "unprognostic (2.36e-1)" "unprognostic (9.80e-2)" "unprognostic (1.69e-1)" "unprognostic (8.33e-2)" "prognostic unfavorable (1.93e-5)" "unprognostic (1.11e-2)" "unprognostic (4.99e-2)" "unprognostic (6.20e-3)" "prognostic unfavorable (1.16e-4)" 30.1 9.9 19.3 19.2 23.2 1.9 14.8 27.0 15.0 20.8 28.3 11.9 8.0 19.2 6.2 16.1 13.2 38.9 67.3 14.3 22.7 15.2 7.5 55.1 16.5 32.0 28.1 12.4 31.6 16.1 3.6 33.4 28.6 13.9 12.2 46.8 7.7 14.6 14.3 5.2 9.4 25.4 27.3 17.9 9.8 13.5 30.3 8.6 52.2 24.2 15.7 30.0 10.1 30.6 7.0 7.1 54.7 4.2 73.2 58.7 21.1 64.9 90.1 72.6 83.5 58.5 1.0 2.8 43.8 174.1 52.3 15.3 7.4 31.6 97.9 6.5 3.7 1.3 42.3 8.4 241.5 1.8 80.6 77.8 10.1 87.4 21.5 351.3 69.3 5.0 0.1 1.0 25.7 1.3 2.8 0.1 10.1 0.1 5.5 4.8 41.0 0.2 14.6 1.2 1.0 5.6 134.8 10.6 6.4 55.1 24.2 4.3 93.9 37.7 41.3 150.5 29.1 6.9 19.7 0.4 76.8 6.5 82.4 1.1 0.1 0.0 1.9 1.7 1.1 0.5 0.6 1.7 0.4 0.3 1.2 0.8 0.0 3.9 1.9 0.4 0.2 0.5 19.3 23.2 27.0 15.0 14.3 22.7 32.0 28.1 28.6 27.3 30.3 30.6 90.1 86.6 5.8 28.7 4.9 5.0 8.0 25.4 6.8 6.1 2.4 5.7 90.5 7.2 6.5 27.6 264.8 1.8 19.2 0.5 0.0 32.0 7.0 4.0 20.1 121.5 0.0 6.1 0.9 6.4 65.3 44.8 1.1 2.2 26.6 24.9 130.3 3.5 6.8 1.7 14.9 0.5 4.1 18.4 7.3 9.4 5.0 7.1 7.2 92.8 4.0 6.0 35.0 13.0 57.6 6.4 0.1 13.9 8.6 5.2 0.8 1.3 1.0 66.8 0.0 24.0 28.7 1.0 1.1 2.7 4.4 3.3 14.2 3.1 0.1 1.3 HELLS "LSH, Nbla10143, PASG, SMARCA6" ENSG00000119969 "Helicase, lymphoid specific" Q9NRZ9 10 94501434-94613905 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Developmental protein, Helicase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.3;lymphoid tissue: 15.9" "Cell type enhanced" "Detected in many" "Spermatocytes: 182.0;Spermatogonia: 173.9" "Cancer enhanced" "Detected in all" "testis cancer: 16.1" "Region enhanced" "Detected in many" "cerebellum: 5.5" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 36.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004491, HPA063242" Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" No Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus, Vesicles" "CAB004491: AB_627895, HPA063242: AB_2684968" "unprognostic (1.94e-1)" "prognostic favorable (1.36e-4)" "unprognostic (9.85e-2)" "unprognostic (3.38e-2)" "unprognostic (8.65e-2)" "unprognostic (4.85e-3)" "unprognostic (1.76e-5)" "unprognostic (7.59e-3)" "unprognostic (7.03e-3)" "unprognostic (6.49e-2)" "unprognostic (2.05e-2)" "unprognostic (9.45e-5)" "unprognostic (9.93e-13)" "unprognostic (2.25e-2)" "unprognostic (1.72e-1)" "unprognostic (6.24e-2)" "unprognostic (3.03e-2)" 1.1 1.2 0.8 6.4 0.3 16.3 3.0 5.5 1.2 3.2 1.3 4.3 2.9 2.9 1.4 5.9 1.7 2.0 0.7 0.4 1.3 2.5 1.8 1.7 12.4 0.8 0.8 2.6 1.2 1.4 3.0 4.1 1.0 2.1 5.1 1.1 1.9 1.0 0.3 5.3 3.9 2.2 0.9 4.3 3.7 12.8 0.9 15.9 1.1 0.2 12.6 3.6 3.2 1.5 57.7 55.4 70.6 90.1 2.9 6.4 37.4 42.9 27.8 34.4 54.6 70.3 45.5 70.0 16.7 15.5 29.1 56.3 40.9 34.9 50.7 68.5 45.5 37.3 56.3 58.0 1.7 71.2 31.6 3.6 2.0 42.1 20.0 9.4 24.0 46.0 20.7 43.5 43.1 54.9 75.2 35.6 73.4 42.3 24.1 70.3 62.1 16.3 24.2 72.2 28.4 22.8 50.3 14.5 7.8 59.0 60.9 23.1 17.2 38.4 19.4 35.4 52.4 22.3 47.6 74.5 19.0 42.8 17.9 0.3 0.7 0.0 7.0 1.5 2.4 18.8 11.4 9.4 2.3 23.2 5.2 7.7 1.0 10.2 1.0 36.8 19.7 2.3 0.8 0.3 5.5 1.2 0.4 1.3 0.8 0.8 1.0 0.9 0.9 1.5 4.7 9.6 3.9 0.0 19.7 21.5 11.5 12.6 13.1 16.4 10.0 15.0 1.0 12.8 12.6 22.0 0.0 46.3 13.2 26.2 3.9 9.0 2.0 9.3 16.4 8.1 10.8 50.5 3.3 6.2 43.4 13.0 17.9 16.3 5.7 60.6 5.7 3.6 15.1 6.7 5.4 17.8 8.2 2.2 10.3 5.3 9.0 7.3 1.8 9.4 5.7 4.3 1.0 4.5 6.6 4.7 1.8 5.7 37.5 3.7 1.7 1.6 6.3 11.4 19.7 10.5 16.4 182.0 173.9 22.9 9.9 11.1 15.7 16.5 30.9 11.7 HEPACAM "FLJ25530, GLIALCAM" ENSG00000165478 "Hepatic and glial cell adhesion molecule" Q14CZ8 11 124919205-124936412 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion, Cell cycle, Growth arrest, Growth regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 222.6;choroid plexus: 79.7" "Group enriched" "Detected in some" 9 "Astrocytes: 184.8;Oligodendrocyte precursor cells: 72.9;Oligodendrocytes: 163.2" "Cancer enriched" "Detected in some" 12 "glioma: 29.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 30 "Hep G2: 25.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017613, CAB025486" Enhanced Approved Vesicles NA NA "Cluster 42: Non-specific - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "CAB025486: , HPA017613: AB_1850595" "unprognostic (3.22e-3)" "unprognostic (1.06e-2)" "unprognostic (1.64e-1)" "unprognostic (6.41e-2)" "unprognostic (1.47e-1)" "unprognostic (9.16e-2)" "unprognostic (2.25e-1)" "unprognostic (7.58e-2)" "unprognostic (1.33e-2)" "unprognostic (1.06e-6)" "unprognostic (2.62e-1)" "unprognostic (3.21e-1)" 15.6 0.3 172.8 0.2 203.3 0.0 2.5 170.4 162.1 0.2 79.7 0.4 0.1 0.1 0.1 0.1 0.0 0.1 0.2 163.2 156.1 0.1 16.2 0.0 0.2 222.6 182.8 0.0 0.0 0.0 0.8 0.0 183.6 0.2 0.2 1.8 0.2 0.5 0.1 0.0 0.2 0.1 205.7 0.0 0.1 0.2 182.0 0.0 0.0 0.3 0.6 0.0 0.1 212.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 25.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.6 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.1 0.1 0.2 172.8 203.3 170.4 162.1 163.2 156.1 222.6 182.8 183.6 205.7 182.0 212.2 0.1 0.0 0.0 184.8 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 11.2 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.6 0.0 15.5 0.0 72.9 163.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 1.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 HEPACAM2 FLJ38683 ENSG00000188175 "HEPACAM family member 2" A8MVW5 7 93188534-93226469 "Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "intestine: 96.2" "Group enriched" "Detected in some" 11 "Enteroendocrine cells: 218.2;Intestinal goblet cells: 387.5;Ionocytes: 349.9;Paneth cells: 318.1" "Group enriched" "Detected in many" 5 "colorectal cancer: 8.4;pancreatic cancer: 10.7;renal cancer: 10.6;stomach cancer: 5.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 36 "SCLC-21H: 172.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA012381 Supported "Nucleoplasm,Vesicles,Mitotic spindle" Yes NA 210000 "Cluster 9: Intestine - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 27: Mucus-secreting cells - Mucin production" "Vesicles, Mitotic spindle" Nucleoplasm "HPA012381: AB_1853037" "unprognostic (2.01e-3)" "unprognostic (6.05e-2)" "prognostic favorable (9.73e-5)" "unprognostic (1.33e-2)" "unprognostic (7.27e-2)" "unprognostic (2.24e-2)" "unprognostic (4.48e-2)" "unprognostic (8.40e-3)" "unprognostic (7.61e-2)" "unprognostic (8.68e-2)" "unprognostic (5.37e-3)" "unprognostic (4.93e-2)" "unprognostic (3.64e-3)" "unprognostic (2.06e-1)" "unprognostic (4.73e-2)" "unprognostic (3.82e-1)" "unprognostic (6.34e-2)" 0.1 0.1 0.0 2.3 0.0 2.5 8.9 0.0 0.1 0.0 0.0 64.3 30.1 0.0 0.5 0.1 0.0 0.2 0.1 0.0 0.0 15.2 0.0 0.1 0.0 0.1 0.1 0.0 4.3 0.4 7.3 0.2 0.0 0.8 96.2 0.0 2.6 1.4 0.0 0.0 48.0 1.5 0.1 0.1 10.1 3.2 0.0 0.1 0.0 0.0 1.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.5 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 172.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.7 0.4 0.3 1.1 0.7 0.0 0.0 15.1 6.6 0.2 0.0 0.9 5.5 0.0 0.0 0.0 17.2 9.8 0.1 2.5 0.0 0.0 0.1 218.2 18.7 0.5 0.0 0.0 0.1 27.5 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.6 387.5 349.9 0.0 0.0 2.4 0.0 0.0 7.2 1.0 0.0 0.0 0.0 0.0 2.2 0.0 318.1 0.0 0.1 0.9 11.5 0.0 0.3 0.0 0.0 0.0 0.1 5.6 1.2 0.0 0.1 0.1 0.1 0.0 19.7 0.3 HES4 bHLHb42 ENSG00000188290 "Hes family bHLH transcription factor 4" Q9HCC6 1 998962-1000172 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 345.1;Paneth cells: 397.4;Prostatic glandular cells: 286.6;Smooth muscle cells: 385.7;Urothelial cells: 494.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "eosinophil: 12.4" "Lineage enriched" "Detected in many" 10 "granulocytes: 12.4" "Cell line enriched" "Detected in many" 7 "HEK 293: 198.1" "Low region specificity" "Detected in all" HPA062465 Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoplasm "Vesicles, Cytosol" "HPA062465: AB_2684771" "unprognostic (6.23e-2)" "unprognostic (3.77e-2)" "unprognostic (7.07e-2)" "prognostic favorable (3.85e-4)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.99e-4)" "unprognostic (6.25e-3)" "unprognostic (2.34e-1)" "unprognostic (1.62e-2)" "unprognostic (3.77e-1)" "unprognostic (7.76e-2)" "prognostic unfavorable (6.27e-4)" "unprognostic (3.97e-1)" "unprognostic (3.87e-2)" "unprognostic (1.86e-1)" "unprognostic (5.08e-3)" 10.5 1.9 12.9 0.7 15.3 0.5 9.1 8.1 34.3 9.2 0.9 11.0 1.2 10.5 0.4 7.5 10.3 0.1 22.6 6.8 17.9 13.6 3.0 10.8 0.2 22.3 15.8 3.9 5.6 0.9 8.4 1.5 17.0 11.4 0.3 0.8 7.7 2.2 4.0 8.4 3.9 1.2 6.0 4.4 5.6 2.6 24.0 1.4 6.0 0.9 0.3 10.0 8.4 4.0 14.3 1.6 1.5 0.2 0.2 0.1 17.6 8.6 1.0 5.2 5.4 2.3 4.5 0.0 20.0 0.7 2.3 25.3 2.1 0.3 0.2 0.1 198.1 0.1 2.4 2.9 1.7 0.0 1.7 0.1 2.0 0.3 0.4 0.7 0.6 2.5 4.1 0.3 0.0 7.6 11.7 0.6 0.2 3.1 19.2 0.2 1.9 4.4 2.0 0.0 1.1 4.6 5.8 14.3 29.1 0.7 10.5 0.0 1.1 1.6 0.6 0.0 4.0 0.0 0.0 0.0 0.1 0.3 0.5 0.0 0.0 12.4 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 12.9 15.3 8.1 34.3 6.8 17.9 22.3 15.8 17.0 6.0 24.0 4.0 90.1 0.0 0.0 18.6 15.3 52.1 345.1 1.7 6.8 8.9 158.9 149.4 13.3 20.0 4.0 58.8 0.0 1.5 22.3 88.3 31.3 44.1 1.0 74.7 30.0 63.4 10.7 2.7 12.9 2.9 43.9 65.5 11.2 153.3 53.5 3.1 37.5 0.8 4.8 0.0 25.9 25.4 4.1 10.0 120.5 1.5 7.5 70.8 115.6 11.2 5.2 129.7 12.3 8.5 1.7 10.7 397.4 15.4 2.3 286.6 1.5 0.8 1.1 11.3 164.3 157.8 385.7 3.2 29.6 43.0 82.7 3.4 27.4 2.0 56.9 494.9 HEXA ENSG00000213614 "Hexosaminidase subunit alpha" P06865 15 72340924-72376420 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 234.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018082, HPA054583" Supported Supported Vesicles,Cytosol "Intracellular and membrane" NA NA 20000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Vesicles Cytosol "HPA018082: , HPA054583: AB_2682531" "unprognostic (1.51e-2)" "unprognostic (1.73e-2)" "unprognostic (3.41e-1)" "prognostic favorable (5.63e-8)" "unprognostic (6.58e-2)" "unprognostic (1.32e-2)" "unprognostic (1.34e-2)" "unprognostic (2.82e-2)" "unprognostic (3.75e-1)" "unprognostic (1.09e-1)" "unprognostic (1.59e-2)" "unprognostic (9.98e-2)" "unprognostic (3.98e-1)" "unprognostic (7.05e-3)" "unprognostic (3.02e-2)" "unprognostic (4.73e-2)" "unprognostic (8.69e-2)" 49.8 56.1 18.3 37.6 21.1 110.0 58.5 20.4 21.6 73.8 28.5 55.1 49.8 42.6 164.6 24.8 47.8 76.7 54.3 19.9 20.1 90.1 79.4 84.2 54.2 23.0 21.3 39.3 30.6 54.0 26.3 102.0 24.6 45.3 67.0 32.1 45.0 53.3 22.1 21.8 41.2 59.5 21.7 54.7 45.1 35.6 27.0 38.1 76.5 33.2 42.4 71.6 19.7 29.9 39.8 66.4 27.8 53.8 223.6 253.1 39.7 54.8 274.1 115.3 182.8 34.6 282.7 32.9 50.9 110.0 59.9 77.1 74.5 34.6 72.5 26.5 30.0 41.4 60.4 60.9 172.9 99.9 113.1 216.7 101.3 50.4 89.3 210.3 107.4 48.4 65.1 197.6 156.0 33.9 21.7 50.0 16.0 128.9 0.3 22.3 60.6 75.3 129.1 61.6 23.8 26.4 136.5 126.6 307.3 56.1 23.4 123.9 54.1 171.9 70.7 160.1 59.3 104.7 151.8 33.4 62.1 130.4 85.3 24.2 84.6 60.1 43.8 35.7 38.7 41.1 28.8 38.9 98.0 38.0 22.5 33.2 8.1 51.3 13.3 37.3 28.2 63.0 18.3 21.1 20.4 21.6 19.9 20.1 23.0 21.3 24.6 21.7 27.0 29.9 68.9 64.1 62.4 19.9 46.3 22.2 33.3 94.3 19.4 42.4 28.6 30.4 26.9 30.0 68.0 66.2 106.3 150.2 54.2 36.6 60.7 88.3 20.6 27.2 30.2 50.8 47.2 19.1 22.7 38.0 68.0 78.7 42.8 40.6 29.9 49.9 43.5 42.9 234.3 26.9 24.7 46.3 81.4 92.8 75.0 13.7 74.3 118.1 94.3 24.4 60.3 38.4 82.4 20.6 26.7 39.1 74.6 44.8 37.7 33.0 68.5 66.7 37.5 56.9 46.0 24.5 31.7 24.3 32.3 13.5 15.6 157.6 36.7 45.2 50.6 27.5 HEXIM1 "CLP-1, EDG1, HIS1, MAQ1" ENSG00000186834 "HEXIM P-TEFb complex subunit 1" O94992 17 45148475-45152099 "Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 467.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008926, CAB011625" Supported Enhanced Nucleoplasm,Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 20: HeLa - Mitochondria" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Vesicles "CAB011625: AB_2233058, HPA008926: AB_1079048" "unprognostic (2.82e-2)" "unprognostic (1.08e-1)" "unprognostic (1.15e-1)" "unprognostic (2.72e-2)" "unprognostic (2.39e-1)" "unprognostic (2.27e-1)" "unprognostic (1.10e-1)" "unprognostic (1.34e-2)" "unprognostic (4.74e-2)" "unprognostic (1.44e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (1.83e-2)" "unprognostic (2.77e-1)" "unprognostic (1.58e-1)" "unprognostic (2.89e-3)" "unprognostic (1.26e-2)" 16.8 32.6 16.3 13.2 15.4 36.3 17.0 16.2 16.5 17.2 16.5 22.5 17.7 19.6 15.9 24.2 21.3 14.3 15.0 14.8 16.8 21.1 26.8 17.3 12.8 17.0 19.1 14.4 19.7 14.1 19.2 25.2 16.0 24.2 10.2 9.0 19.2 19.8 33.2 22.6 24.9 13.0 17.7 25.6 23.1 21.6 19.7 15.4 20.1 21.6 12.4 19.7 17.6 14.2 35.7 111.1 22.8 33.0 36.7 19.6 55.3 30.9 27.8 25.0 27.8 52.6 49.3 15.5 93.1 32.7 12.1 28.2 13.8 30.4 20.0 32.2 32.9 48.2 65.8 65.0 32.0 30.3 61.4 23.0 25.5 18.6 8.1 62.6 12.7 26.8 21.5 36.6 19.0 47.8 31.9 34.9 20.9 32.9 33.4 13.1 19.9 19.2 66.5 62.1 12.2 9.2 46.6 52.0 52.2 23.0 54.2 23.5 24.3 25.1 34.6 14.6 58.5 33.1 11.4 10.0 23.0 28.1 29.1 16.2 4.0 6.8 4.2 6.1 2.4 3.0 4.2 3.7 3.3 3.2 3.7 3.9 10.0 3.7 7.3 3.4 3.8 2.2 16.3 15.4 16.2 16.5 14.8 16.8 17.0 19.1 16.0 17.7 19.7 14.2 210.3 73.7 111.8 7.2 76.1 84.5 75.0 57.7 157.1 25.1 127.0 215.9 59.7 87.2 60.5 25.8 22.9 134.8 114.3 250.4 7.9 35.0 2.2 88.8 66.1 91.3 52.8 82.1 10.7 23.6 70.1 99.2 94.3 137.9 125.9 16.5 42.5 40.5 42.1 15.2 12.9 122.0 54.9 33.9 83.2 3.0 35.1 83.0 53.4 9.4 38.4 27.7 28.8 7.1 8.2 25.3 127.1 43.6 44.1 52.1 184.9 53.8 45.7 24.8 26.3 249.2 128.2 2.6 7.9 126.7 71.5 467.5 111.1 16.9 92.2 34.4 HFM1 "FLJ36760, FLJ39011, MER3, SEC63D1" ENSG00000162669 "Helicase for meiosis 1" A2PYH4 1 91260766-91404856 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Meiosis "Helicase, Hydrolase" "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 9.3;testis: 13.8" "Cell type enhanced" "Detected in some" "Astrocytes: 50.9;Inhibitory neurons: 38.4;Oligodendrocyte precursor cells: 90.5;Spermatocytes: 58.9" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 5.2;AN3-CA: 2.8;K-562: 3.0;SH-SY5Y: 2.1;U-266/70: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035036, HPA035557" Supported "Golgi apparatus,Vesicles" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA035036: AB_2797224, HPA035557: AB_10696507" "unprognostic (1.35e-2)" "unprognostic (9.39e-2)" "unprognostic (1.17e-1)" "unprognostic (2.83e-4)" "unprognostic (2.05e-2)" "unprognostic (1.52e-1)" "unprognostic (7.43e-3)" "unprognostic (1.79e-1)" "unprognostic (7.75e-2)" "unprognostic (7.97e-2)" "unprognostic (1.76e-4)" "unprognostic (2.81e-2)" "unprognostic (1.06e-2)" "unprognostic (2.89e-3)" "unprognostic (2.78e-2)" "unprognostic (1.77e-4)" "unprognostic (9.59e-2)" 0.4 0.3 1.0 0.1 1.0 0.2 0.4 5.1 1.0 0.9 0.0 0.5 0.3 2.3 1.1 0.1 0.8 0.2 0.6 0.7 1.6 0.7 0.1 0.2 0.1 1.7 1.6 3.9 0.7 0.1 9.3 0.5 1.1 0.6 0.3 4.5 0.5 1.1 1.5 0.1 0.2 0.9 1.1 0.4 0.2 13.8 1.6 0.1 1.6 1.1 0.2 0.4 0.3 1.3 0.0 0.1 5.2 2.8 0.0 0.1 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 0.1 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.0 0.0 0.3 0.1 1.6 0.0 0.0 0.2 1.0 0.0 0.0 0.0 1.7 2.1 0.0 0.0 0.7 1.4 0.0 0.5 0.0 0.0 0.5 0.5 0.1 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 5.1 1.0 0.7 1.6 1.7 1.6 1.1 1.1 1.6 1.3 0.2 0.0 1.1 50.9 0.0 0.0 0.0 0.0 0.6 3.9 0.1 0.3 3.1 0.0 0.0 0.0 6.2 0.5 0.0 0.0 0.0 0.4 17.8 0.2 1.9 0.4 0.0 2.5 17.6 0.2 0.2 0.6 0.0 0.0 0.0 5.9 0.0 0.0 0.1 0.0 38.4 0.0 0.0 0.0 0.0 5.0 4.1 0.0 0.0 10.3 0.0 2.4 0.0 90.5 9.5 0.1 0.0 2.2 0.0 0.1 0.0 0.0 0.0 6.2 0.0 2.0 1.4 58.9 15.6 0.0 0.0 0.0 0.0 1.8 0.0 0.0 HIP1 ILWEQ ENSG00000127946 "Huntingtin interacting protein 1" O00291 7 75533298-75738962 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Apoptosis, Differentiation, Endocytosis, Transcription, Transcription regulation" "Actin-binding, Activator" "Cancer-related genes, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.9" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1373.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 9.5;eosinophil: 6.8;neutrophil: 6.8;NK-cell: 3.0;plasmacytoid DC: 3.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 55.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013606, CAB015334, CAB016402, HPA017964" Enhanced Supported Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "CAB015334: AB_2117565, CAB016402: AB_627725, HPA013606: AB_1850717, HPA017964: AB_1850719" "unprognostic (8.23e-2)" "unprognostic (1.22e-1)" "unprognostic (2.20e-2)" "unprognostic (1.64e-1)" "unprognostic (1.04e-1)" "unprognostic (2.59e-1)" "unprognostic (2.73e-3)" "unprognostic (1.03e-2)" "unprognostic (1.11e-2)" "unprognostic (2.02e-2)" "unprognostic (2.70e-2)" "unprognostic (7.98e-2)" "unprognostic (1.73e-3)" "unprognostic (9.67e-2)" "unprognostic (1.75e-1)" "unprognostic (1.00e-2)" "unprognostic (1.09e-1)" 16.7 7.9 23.6 7.3 38.7 5.4 13.2 29.8 29.0 11.7 14.4 6.1 2.7 9.8 9.2 5.3 12.9 8.3 9.0 22.4 24.9 14.8 9.3 18.5 4.7 34.6 35.4 8.0 3.8 4.2 3.4 19.7 32.0 6.8 4.1 4.6 4.0 11.2 4.2 10.6 5.0 12.2 24.5 11.2 4.8 30.4 34.8 3.1 15.3 8.4 4.5 9.0 7.9 50.9 5.2 55.9 37.1 35.2 15.3 20.8 11.1 9.7 6.3 6.2 4.6 3.2 5.0 3.8 11.2 24.2 21.6 6.3 38.1 8.0 8.3 3.1 7.1 3.0 6.6 5.3 15.2 0.8 14.8 16.0 4.8 20.4 4.2 11.4 26.3 4.2 4.0 3.6 10.1 21.6 2.5 22.2 40.5 0.5 6.6 4.4 15.5 0.3 4.7 20.0 1.8 16.2 9.0 5.6 12.5 32.8 34.6 13.9 9.4 18.0 13.7 6.2 13.6 4.0 0.4 8.9 18.1 8.0 12.4 9.5 0.9 6.8 0.9 0.9 0.7 0.3 0.1 0.7 1.4 0.4 0.1 0.5 6.8 3.0 0.7 3.3 1.4 0.3 23.6 38.7 29.8 29.0 22.4 24.9 34.6 35.4 32.0 24.5 34.8 50.9 54.0 60.9 37.5 43.8 7.8 17.6 6.2 7.1 20.5 12.0 14.8 10.7 14.3 11.5 12.2 27.6 12.5 2.1 27.2 2.2 13.7 14.4 256.9 15.5 24.2 54.3 4.8 7.8 16.3 6.0 10.0 17.1 6.1 25.5 14.0 25.9 36.8 22.5 14.9 23.5 19.0 3.0 6.1 18.5 49.1 1373.3 22.4 24.1 10.6 45.9 9.4 14.3 21.6 336.3 313.7 3.1 7.7 24.8 18.4 4.2 0.3 2.6 1.3 9.4 85.5 25.9 44.8 12.1 5.6 5.6 9.1 0.8 13.5 7.7 3.3 3.5 HIP1R "FLJ14000, HIP12, HIP3, ILWEQ, KIAA0655" ENSG00000130787 "Huntingtin interacting protein 1 related" O75146 12 122834453-122862961 "Cancer-related genes, Predicted intracellular proteins" Endocytosis Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 103.4" "Cell type enhanced" "Detected in many" "Astrocytes: 134.5;Oligodendrocyte precursor cells: 168.9;Oligodendrocytes: 117.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 9.3;naive B-cell: 10.6" "Group enriched" "Detected in many" 8 "B-cells: 10.6;granulocytes: 2.9;T-cells: 3.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017187, HPA038135, HPA038136" Enhanced Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Cytosol" Vesicles "CAB017187: , HPA038135: AB_2675851, HPA038136: AB_2675852" "unprognostic (4.52e-1)" "unprognostic (6.39e-2)" "unprognostic (7.07e-2)" "unprognostic (6.55e-3)" "unprognostic (8.67e-2)" "unprognostic (1.00e-2)" "unprognostic (1.02e-2)" "unprognostic (8.11e-2)" "unprognostic (6.37e-2)" "unprognostic (1.76e-1)" "unprognostic (1.39e-2)" "unprognostic (6.72e-2)" "prognostic favorable (6.50e-7)" "unprognostic (2.18e-2)" "unprognostic (2.84e-1)" "unprognostic (2.54e-3)" "prognostic favorable (7.26e-4)" 18.5 24.0 68.6 10.4 95.5 13.3 22.6 78.8 80.3 16.0 33.5 16.3 31.8 9.0 3.8 18.0 9.0 7.7 18.9 68.0 67.8 50.2 25.6 15.4 17.5 87.3 83.8 5.6 50.2 8.9 42.0 4.7 75.6 21.0 4.9 5.5 58.7 10.5 7.2 51.7 36.0 2.2 65.3 20.9 66.7 8.5 85.7 12.6 21.5 4.4 11.7 11.4 19.7 103.4 38.1 10.8 8.0 33.1 2.3 6.1 39.2 5.9 9.5 5.9 4.6 16.8 11.1 36.0 19.0 4.3 8.9 32.4 9.7 21.4 0.5 5.8 14.0 0.8 13.8 17.8 7.1 2.8 24.5 3.8 14.9 8.0 13.4 8.1 40.5 16.5 9.6 2.0 3.4 54.4 17.4 8.8 7.4 32.8 12.8 9.0 10.2 12.5 19.6 45.4 8.1 17.9 7.1 18.0 9.5 4.3 36.6 1.5 32.8 3.7 27.5 11.7 5.7 24.8 14.2 21.8 6.0 6.0 3.1 0.0 0.0 2.9 2.7 0.0 1.5 9.3 1.7 2.1 0.0 10.6 3.0 1.9 0.2 0.7 0.0 0.0 0.4 2.0 68.6 95.5 78.8 80.3 68.0 67.8 87.3 83.8 75.6 65.3 85.7 103.4 57.0 0.0 13.4 134.5 38.0 13.3 16.8 8.4 6.8 16.4 21.2 18.2 4.2 60.1 11.1 60.7 29.2 3.7 18.2 28.4 0.0 40.1 3.1 21.9 4.7 18.2 7.8 1.3 11.2 28.7 13.1 2.3 80.5 37.5 5.7 25.3 19.2 24.4 0.6 18.5 9.7 29.9 22.4 1.2 4.2 2.9 1.5 2.2 10.6 9.4 0.1 12.5 7.2 168.9 117.8 22.7 25.3 1.2 17.2 20.2 47.5 17.9 14.2 16.6 0.0 2.5 4.1 6.5 13.3 11.5 21.0 1.9 15.0 1.3 23.9 28.4 HK2 ENSG00000159399 "Hexokinase 2" P52789 2 74834127-74893359 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 144.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 216.4;Early spermatids: 89.5;Paneth cells: 108.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 51.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 172.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA028587, HPA061711" Enhanced Supported Vesicles,Centrosome,Mitochondria,Cytosol NA NA 100000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Mitochondria, Cytosol" "Vesicles, Centrosome" "HPA028587: AB_10602605, HPA061711: " "unprognostic (1.28e-1)" "unprognostic (1.52e-3)" "unprognostic (3.02e-1)" "unprognostic (3.63e-2)" "unprognostic (1.69e-1)" "unprognostic (7.21e-2)" "prognostic unfavorable (3.65e-4)" "unprognostic (2.85e-2)" "unprognostic (2.57e-1)" "unprognostic (2.17e-1)" "unprognostic (4.43e-3)" "unprognostic (2.24e-2)" "prognostic unfavorable (1.37e-4)" "unprognostic (1.20e-1)" "unprognostic (1.17e-1)" "unprognostic (1.42e-1)" "unprognostic (7.67e-2)" 58.2 2.7 2.7 14.6 3.9 45.7 16.0 4.8 5.6 7.8 2.7 46.6 2.8 5.1 66.1 19.9 9.7 9.5 7.9 3.5 3.6 1.9 2.7 15.2 5.8 11.1 6.3 14.9 2.9 2.5 1.9 13.1 8.5 4.9 37.3 144.0 14.7 1.1 45.6 14.6 13.0 3.3 5.9 6.9 18.7 32.8 6.0 3.7 14.1 83.7 7.8 27.1 15.9 8.6 55.9 0.4 12.5 45.4 103.3 10.8 46.5 21.3 30.6 23.4 33.4 44.0 9.8 40.7 20.1 9.9 30.2 19.0 57.0 44.7 67.0 11.6 12.5 55.1 12.4 61.0 32.5 80.8 86.3 18.2 47.3 44.5 77.1 26.3 11.3 23.0 49.2 0.2 6.9 39.6 19.8 82.0 45.3 52.4 38.2 31.8 26.2 31.7 14.2 77.2 9.2 44.6 13.5 67.4 27.4 17.8 3.6 12.8 9.4 74.0 13.4 31.2 39.2 27.1 8.2 20.2 172.5 57.9 19.9 16.8 14.0 51.7 0.2 11.0 0.6 1.2 0.8 0.1 11.8 1.3 1.2 1.2 11.2 0.0 7.7 0.3 1.5 4.7 2.7 3.9 4.8 5.6 3.5 3.6 11.1 6.3 8.5 5.9 6.0 8.6 1.6 16.0 45.3 4.9 5.7 51.6 9.5 26.7 5.7 14.8 16.0 5.6 7.2 4.3 24.2 5.5 83.4 2.3 0.6 216.4 0.0 4.6 89.5 5.8 4.1 4.4 39.0 4.2 0.2 4.5 33.5 6.4 14.8 15.0 22.2 27.2 1.4 0.3 15.8 21.9 0.1 37.7 6.1 20.8 35.1 46.0 14.6 22.8 23.2 25.3 18.9 6.3 2.1 0.5 0.7 25.6 108.3 7.9 4.7 34.3 5.4 0.2 15.2 42.1 13.1 19.9 3.3 3.9 4.2 10.7 57.0 8.2 3.6 5.8 51.7 70.0 HLA-DMA "D6S222E, RING6" ENSG00000204257 "Major histocompatibility complex, class II, DM alpha" P28067 6 32948613-32969094 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 120.4" "Cell type enhanced" "Detected in many" "B-cells: 400.4;Hofbauer cells: 354.3;Kupffer cells: 411.6;Langerhans cells: 1350.5;Macrophages: 591.4;monocytes: 332.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "classical monocyte: 3.8;intermediate monocyte: 3.8;memory B-cell: 6.3;myeloid DC: 7.2;naive B-cell: 6.4;plasmacytoid DC: 5.2" "Group enriched" "Detected in many" 12 "B-cells: 6.4;dendritic cells: 7.2;monocytes: 3.8" "Group enriched" "Detected in some" 5 "U-266/70: 30.5;U-698: 94.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012750, HPA017295" Enhanced Approved Vesicles NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA012750: AB_1853926, HPA017295: AB_2669575" "unprognostic (1.69e-3)" "unprognostic (3.52e-2)" "unprognostic (8.03e-2)" "prognostic favorable (4.64e-5)" "unprognostic (3.99e-1)" "unprognostic (3.90e-2)" "unprognostic (1.60e-1)" "prognostic favorable (4.59e-4)" "unprognostic (7.01e-2)" "unprognostic (9.69e-2)" "unprognostic (6.66e-2)" "unprognostic (1.89e-1)" "unprognostic (2.12e-3)" "unprognostic (1.41e-1)" "unprognostic (4.95e-2)" "unprognostic (3.80e-1)" "unprognostic (2.14e-2)" 79.9 63.6 0.1 1.0 0.1 23.4 63.4 0.1 0.6 33.1 0.5 26.7 1.6 19.8 22.8 16.0 31.4 0.9 23.5 0.1 0.2 48.0 15.1 98.3 2.4 0.3 0.2 13.5 19.4 0.1 15.6 0.9 0.2 23.1 13.6 0.4 25.9 0.3 11.8 25.1 69.6 0.5 0.3 120.4 32.7 4.0 0.2 0.6 33.1 0.2 36.9 21.3 20.8 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 2.1 0.1 0.1 0.0 0.1 0.0 0.5 1.9 0.0 0.0 0.5 0.3 0.3 2.5 0.4 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.1 0.0 0.9 0.0 0.7 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.1 30.5 13.7 94.3 0.6 0.0 0.0 0.0 3.8 0.3 0.2 3.8 0.0 6.3 0.1 0.2 7.2 6.4 0.0 0.1 0.4 0.3 1.2 5.2 0.4 3.6 0.1 0.1 0.1 0.6 0.1 0.2 0.3 0.2 0.2 0.3 0.2 0.5 240.5 73.7 171.3 0.7 400.4 48.3 15.5 77.3 17.6 1.8 38.2 32.0 5.2 45.8 95.9 53.3 2.1 4.9 175.6 19.3 17.6 101.0 3.4 12.5 3.1 123.6 3.0 30.5 0.8 51.1 4.2 16.4 43.8 24.5 41.2 8.2 37.1 4.4 354.3 0.0 1.2 25.0 22.4 411.6 1350.5 5.3 16.1 591.4 80.0 14.0 332.4 4.3 33.0 1.5 1.3 26.6 46.2 18.8 68.9 19.1 267.0 47.1 77.6 1.3 19.7 5.4 15.6 4.1 4.8 7.0 41.9 4.0 44.7 4.3 42.6 60.9 HLA-DMB "D6S221E, RING7" ENSG00000242574 "Major histocompatibility complex, class II, DM beta" P28068 6 32934629-32941028 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 78.8;lymphoid tissue: 101.5" "Group enriched" "Detected in many" 4 "B-cells: 228.5;dendritic cells: 129.4;Hofbauer cells: 274.8;Kupffer cells: 201.9;Langerhans cells: 472.8;Macrophages: 272.4;monocytes: 187.1;Proximal enterocytes: 284.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 6 "B-cells: 128.8;dendritic cells: 85.3;monocytes: 73.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 14.2;Daudi: 27.6;EFO-21: 12.4;U-266/70: 7.8;U-698: 31.9" "Low region specificity" "Detected in all" "HPA012298, HPA077524" Supported Supported Vesicles NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA012298: AB_1853927, HPA077524: " "unprognostic (5.34e-2)" "unprognostic (1.63e-2)" "unprognostic (2.45e-2)" "prognostic favorable (3.89e-5)" "unprognostic (3.07e-1)" "unprognostic (7.64e-3)" "unprognostic (4.00e-1)" "unprognostic (3.46e-3)" "unprognostic (6.99e-2)" "unprognostic (8.76e-2)" "unprognostic (8.93e-2)" "unprognostic (2.73e-1)" "unprognostic (6.82e-3)" "unprognostic (2.03e-1)" "unprognostic (4.14e-2)" "unprognostic (8.35e-2)" "unprognostic (5.60e-2)" 38.3 35.9 0.1 13.2 0.2 6.9 25.7 0.3 1.0 21.6 0.1 19.9 0.0 14.6 7.4 9.3 14.6 0.1 11.1 0.0 0.6 41.9 7.8 59.9 17.6 0.3 0.4 9.5 9.1 0.0 9.2 0.8 0.2 13.1 14.9 0.5 14.7 0.0 5.3 14.3 78.8 0.0 0.9 101.5 17.6 2.2 0.1 9.9 45.9 0.0 18.8 14.4 10.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.2 27.6 12.4 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 7.8 0.4 31.9 0.0 0.1 0.0 0.5 73.2 16.7 1.2 73.8 2.6 94.0 1.0 2.9 85.0 128.8 0.7 2.4 4.7 16.2 28.1 85.3 6.7 71.4 0.1 0.2 0.3 1.0 0.0 0.6 0.3 0.4 0.2 0.9 0.1 1.1 36.8 9.6 57.0 0.7 228.5 12.0 1.0 5.4 2.2 0.2 2.5 4.7 2.6 5.7 12.7 16.5 0.0 1.7 129.4 3.3 11.7 28.8 0.5 7.5 5.4 37.2 4.2 10.3 0.8 4.4 1.6 3.8 3.1 38.5 15.2 22.7 5.7 0.5 274.8 0.0 0.6 8.5 2.0 201.9 472.8 1.5 3.4 272.4 16.0 27.2 187.1 0.5 21.6 1.0 0.1 2.5 17.8 1.9 3.8 1.3 284.8 7.4 16.8 1.1 6.6 1.6 3.1 0.6 0.7 1.1 10.9 2.7 17.6 0.9 10.3 8.7 HLA-DPA1 HLA-DP1A ENSG00000231389 "Major histocompatibility complex, class II, DP alpha 1" P20036 6 33064569-33080775 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 319.9;lymphoid tissue: 359.6" "Cell type enhanced" "Detected in many" "B-cells: 1387.3;Kupffer cells: 1794.6;Langerhans cells: 8122.8;Macrophages: 2736.9;monocytes: 2940.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 81.8;intermediate monocyte: 187.4;memory B-cell: 150.4;myeloid DC: 296.0;naive B-cell: 136.5;non-classical monocyte: 124.1;plasmacytoid DC: 82.6" "Group enriched" "Detected in all" 7 "B-cells: 150.4;dendritic cells: 296.0;monocytes: 187.4" "Cell line enhanced" "Detected in many" "Daudi: 37.2;HDLM-2: 115.9;REH: 30.3;U-698: 26.1" HPA017967 Enhanced Supported Vesicles NA NA 240000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA017967: AB_1853929" "unprognostic (8.93e-3)" "unprognostic (3.15e-2)" "unprognostic (3.64e-2)" "unprognostic (9.40e-3)" "unprognostic (9.07e-2)" "unprognostic (2.80e-2)" "unprognostic (5.69e-2)" "unprognostic (1.82e-2)" "unprognostic (7.28e-2)" "unprognostic (1.39e-1)" "unprognostic (1.93e-1)" "unprognostic (1.80e-1)" "unprognostic (8.38e-2)" "unprognostic (1.17e-1)" "unprognostic (4.69e-2)" "unprognostic (8.11e-2)" "unprognostic (1.06e-1)" 180.8 108.0 2.2 33.4 2.0 12.8 138.4 2.7 3.3 76.7 2.5 72.1 20.2 55.3 8.3 43.1 63.0 13.0 62.0 2.0 3.4 99.0 36.8 319.9 51.3 4.9 2.8 24.9 28.6 5.9 58.0 3.4 4.3 64.0 16.1 2.0 59.5 16.2 29.5 66.3 174.4 14.6 4.3 359.6 52.1 13.4 3.1 30.2 76.6 7.3 51.5 58.6 60.0 4.4 0.1 0.0 0.0 0.0 0.8 1.3 1.1 0.4 0.4 0.5 0.0 0.0 4.9 37.2 5.0 0.9 7.1 0.0 0.0 0.0 0.1 115.9 2.5 6.2 0.0 0.0 0.1 0.0 11.6 1.7 0.0 2.2 0.0 0.0 0.6 0.0 0.0 3.3 0.0 0.0 0.1 0.1 0.6 0.0 0.0 30.3 0.0 4.9 0.1 0.0 0.1 0.0 0.0 0.0 2.9 0.0 0.0 1.3 2.6 7.8 0.1 0.1 0.0 5.6 0.9 26.1 12.2 0.2 4.4 2.2 81.8 6.6 21.6 187.4 5.7 150.4 9.6 23.9 296.0 136.5 3.4 15.7 3.0 20.9 124.1 82.6 29.2 136.0 2.2 2.0 2.7 3.3 2.0 3.4 4.9 2.8 4.3 4.3 3.1 4.4 621.8 83.3 404.3 0.3 1387.3 206.7 7.2 12.4 9.1 2.8 41.2 110.4 12.1 64.3 107.3 23.9 0.0 4.2 574.9 10.6 9.8 36.4 2.8 1.2 4.1 337.8 10.2 80.3 0.5 18.8 9.3 53.7 48.4 2.8 64.6 14.3 62.2 7.5 1153.8 5.0 0.9 18.2 12.2 1794.6 8122.8 11.7 18.0 2736.9 302.4 32.8 2940.3 5.1 94.7 0.0 0.1 4.7 5.4 27.4 100.2 10.6 114.0 42.7 129.2 5.0 52.6 14.7 29.8 1.3 4.8 6.0 175.2 6.8 157.8 11.5 28.6 34.4 HLA-E ENSG00000204592 "Major histocompatibility complex, class I, E" P13747 6 30489509-30494194 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 2347.3;Hepatic stellate cells: 1647.8;NK-cells: 1874.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebral cortex: 109.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 212.3;U-266/70: 284.8" "CAB024589, HPA031454" Enhanced Approved Vesicles "Secreted to blood" NA NA 100000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB024589: AB_324025, HPA031454: AB_2673891" "unprognostic (1.14e-2)" "unprognostic (1.38e-2)" "unprognostic (9.20e-2)" "unprognostic (2.47e-3)" "unprognostic (2.06e-1)" "unprognostic (3.63e-1)" "unprognostic (1.14e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-2)" "unprognostic (1.35e-2)" "unprognostic (5.57e-2)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.86e-4)" "unprognostic (2.90e-1)" "unprognostic (4.14e-2)" "unprognostic (1.75e-3)" "unprognostic (1.42e-3)" 724.7 217.2 9.6 173.7 10.0 410.3 578.9 10.9 109.5 360.1 7.3 329.4 0.6 313.5 119.3 330.9 336.5 186.1 356.0 7.7 13.1 375.2 332.8 1144.6 336.3 16.6 22.7 213.2 156.6 95.8 121.8 117.3 16.1 251.2 116.8 12.4 252.5 93.0 179.2 518.3 428.9 89.0 10.0 1007.2 259.5 41.1 11.7 86.0 381.9 0.0 137.5 295.0 366.3 14.2 100.7 16.7 6.8 57.0 212.3 166.4 0.9 0.0 0.0 0.1 0.3 40.0 189.1 65.6 98.7 92.7 148.3 121.6 12.8 53.1 0.0 67.6 32.7 78.6 18.7 0.0 0.0 0.2 38.3 135.4 94.4 67.7 0.0 0.0 0.2 34.6 9.8 0.9 54.5 0.2 0.3 0.8 0.5 32.0 0.0 20.6 0.2 97.4 82.7 58.4 0.3 4.8 63.3 56.9 0.3 1.2 0.0 132.7 102.0 60.7 0.1 0.5 14.7 284.8 171.6 29.4 0.3 62.1 149.2 1140.0 335.4 1153.0 723.3 550.2 602.2 449.1 539.9 709.2 158.5 450.3 531.5 547.8 1916.1 512.9 648.0 138.3 611.7 1441.6 9.6 10.0 10.9 109.5 7.7 13.1 16.6 22.7 16.1 10.0 11.7 14.2 2347.3 310.9 411.0 8.1 950.6 484.6 386.6 284.2 183.8 2.7 238.7 204.0 108.3 231.6 270.0 123.2 6.2 88.2 1304.6 603.0 17.6 484.9 5.0 157.7 157.9 1554.7 216.2 172.3 0.1 677.2 277.0 402.8 233.4 325.6 531.6 59.2 1647.8 120.1 700.6 5.0 0.1 545.3 248.2 1220.4 512.2 11.0 132.0 821.6 466.0 105.9 740.5 100.2 1874.4 2.0 0.5 682.2 559.1 76.3 716.6 436.9 473.9 79.9 214.7 9.5 177.5 535.1 350.1 10.6 7.0 170.0 426.5 359.0 1162.1 196.5 285.0 544.4 HMCN2 "DKFZp434P0216, FLJ23816" ENSG00000148357 "Hemicentin 2" Q8NDA2 9 130265882-130434123 "Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 33.9;intestine: 51.1" "Cell type enriched" "Detected in many" 8 "Skeletal myocytes: 283.7" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "pons: 4.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 7.8;RH-30: 18.0;SCLC-21H: 2.6;SH-SY5Y: 4.1;U-138 MG: 2.9;U-87 MG: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA053903, HPA070647" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 27000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA053903: AB_2682301, HPA070647: AB_2686290" "unprognostic (1.61e-1)" "unprognostic (8.05e-3)" "unprognostic (1.69e-1)" "unprognostic (5.53e-4)" "unprognostic (1.05e-1)" "unprognostic (1.12e-2)" "unprognostic (1.10e-1)" "unprognostic (8.78e-3)" "unprognostic (3.23e-1)" "unprognostic (3.97e-4)" "unprognostic (3.36e-2)" "unprognostic (3.93e-1)" "unprognostic (1.04e-3)" "unprognostic (1.53e-2)" "unprognostic (3.62e-2)" "unprognostic (8.96e-3)" "unprognostic (8.63e-2)" 14.4 1.3 0.3 1.5 0.2 0.0 3.9 0.1 0.7 21.4 0.0 51.1 5.2 33.9 0.1 4.8 10.1 0.7 12.4 0.1 0.9 4.0 1.2 3.8 1.2 2.0 0.7 2.6 0.9 0.1 0.3 0.2 4.0 9.2 1.9 0.0 2.2 2.3 25.0 4.1 21.6 4.2 1.2 0.4 4.9 5.7 1.0 1.2 4.8 6.3 0.2 9.2 12.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.4 0.2 0.5 0.0 18.0 0.1 0.0 0.1 2.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.2 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.7 0.1 0.9 2.0 0.7 4.0 1.2 1.0 0.4 1.2 3.2 7.5 2.3 0.5 0.9 0.4 0.0 0.0 1.1 0.2 0.3 4.8 0.0 3.7 0.0 0.0 0.1 0.1 22.9 1.9 0.0 17.0 0.0 0.2 5.0 0.0 0.0 1.3 0.0 0.1 24.8 0.0 0.1 7.6 0.1 0.7 2.3 0.4 1.7 5.8 3.6 2.0 0.8 0.8 10.6 0.0 2.3 1.8 1.0 0.0 0.0 0.0 0.5 0.7 0.1 8.3 0.0 0.1 0.8 34.1 1.2 4.0 0.7 0.0 283.7 4.5 0.9 1.1 0.0 0.6 0.3 1.6 2.9 5.5 4.7 HMOX2 HO-2 ENSG00000103415 "Heme oxygenase 2" P30519 16 4474690-4510347 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 515.3;Late spermatids: 2001.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025464, HPA040611" Supported Approved Vesicles,Cytosol NA NA 12000 "Cluster 20: T-cells - T-cell receptor" "Cluster 43: Testis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Cytosol" "CAB025464: , HPA040611: AB_10961034" "unprognostic (3.33e-1)" "unprognostic (3.58e-2)" "unprognostic (1.11e-1)" "prognostic favorable (7.91e-4)" "unprognostic (2.74e-1)" "unprognostic (4.27e-2)" "unprognostic (6.23e-2)" "unprognostic (5.77e-2)" "unprognostic (1.43e-2)" "unprognostic (3.60e-1)" "unprognostic (7.74e-3)" "unprognostic (9.87e-2)" "prognostic favorable (8.98e-6)" "unprognostic (3.51e-2)" "unprognostic (4.14e-2)" "unprognostic (1.65e-2)" "unprognostic (2.64e-1)" 63.0 51.3 43.7 23.2 51.9 18.3 55.7 56.9 55.2 47.1 36.2 41.0 34.8 35.8 22.5 84.5 35.9 26.9 149.9 47.7 50.0 71.2 109.5 46.6 33.2 55.8 49.2 25.6 39.7 38.6 43.8 17.9 57.1 34.5 25.1 22.5 44.1 14.1 37.9 44.4 42.6 22.7 44.7 67.8 100.2 152.2 54.3 24.3 41.9 32.3 36.3 33.2 49.0 53.5 82.9 38.2 20.5 45.6 65.8 31.5 33.8 53.9 26.5 48.3 43.7 48.3 55.5 36.9 64.0 55.7 34.6 51.5 75.4 126.9 48.4 51.5 48.4 27.5 35.2 63.3 43.7 56.8 44.4 48.7 41.7 55.7 37.6 37.9 83.7 46.9 44.7 18.1 44.5 114.3 48.7 58.4 34.2 81.1 35.7 54.3 33.7 84.4 72.3 51.8 34.4 19.4 43.1 95.1 66.4 33.9 58.2 36.3 91.7 25.7 39.9 120.3 30.1 24.3 30.0 78.0 16.5 52.5 35.2 87.6 37.1 252.6 166.3 46.5 142.1 69.8 153.8 168.5 73.6 66.8 145.5 151.6 125.1 99.0 35.7 39.2 155.4 142.3 43.7 51.9 56.9 55.2 47.7 50.0 55.8 49.2 57.1 44.7 54.3 53.5 33.8 35.3 41.5 7.8 37.2 54.8 35.7 73.5 19.4 29.3 26.4 29.1 70.6 32.9 54.5 36.8 20.9 75.3 59.8 70.7 129.1 79.7 515.3 38.6 30.9 53.4 31.8 14.3 23.0 90.7 69.6 39.4 89.7 53.3 19.7 38.8 75.0 93.0 67.2 28.6 21.6 37.6 85.5 23.9 52.9 2001.6 45.4 30.6 62.2 5.6 29.3 53.9 141.1 9.5 32.9 114.9 70.7 56.1 47.1 37.7 110.8 239.3 39.9 27.8 72.3 14.6 58.0 199.7 149.8 28.2 51.6 38.4 88.3 47.4 48.9 28.7 HNF1B "HNF1beta, LFB3, MODY5, TCF2, VHNF1" ENSG00000275410 "HNF1 homeobox B" P35680 17 37686431-37745105 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 61.1;pancreas: 33.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 78.6;Collecting duct cells: 57.0;Distal tubular cells: 45.0;Ductal cells: 42.0;Early spermatids: 32.3;Glandular and luminal cells: 41.7;Pancreatic endocrine cells: 31.7;Proximal tubular cells: 38.2" "Cancer enhanced" "Detected in many" "renal cancer: 32.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RPTEC TERT1: 139.3" "Region enhanced" "Detected in single" "hypothalamus: 2.0" "Low region specificity" "Detected in single" "HPA002083, CAB068192" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Nucleoplasm Vesicles "CAB068192: AB_2665649, HPA002083: AB_1080232" "unprognostic (2.52e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-2)" "unprognostic (5.29e-3)" "unprognostic (5.29e-2)" "unprognostic (3.00e-2)" "unprognostic (1.58e-2)" "unprognostic (1.31e-1)" "unprognostic (1.29e-1)" "unprognostic (1.51e-1)" "unprognostic (1.71e-2)" "unprognostic (2.33e-1)" "prognostic favorable (6.00e-4)" "unprognostic (7.06e-2)" "unprognostic (2.26e-1)" "unprognostic (7.49e-2)" "prognostic favorable (2.51e-6)" 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 2.7 0.0 9.9 6.9 1.5 7.5 0.0 5.7 15.1 0.0 0.0 0.1 61.1 12.9 6.8 0.0 0.0 0.0 0.0 33.0 3.5 0.0 0.0 0.0 2.3 7.1 0.0 0.0 4.4 0.0 0.0 8.6 0.1 0.0 0.0 8.2 3.9 0.1 0.0 0.0 0.0 0.0 3.2 0.1 0.0 0.0 19.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.7 2.2 0.0 28.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.1 139.3 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.6 14.1 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.0 0.6 78.6 1.9 57.0 0.0 0.0 0.0 15.4 45.0 42.0 32.3 18.5 3.6 0.4 14.4 0.0 0.2 25.4 0.0 0.2 13.7 41.7 5.7 0.0 0.0 5.1 0.1 0.0 0.2 13.5 0.0 0.3 0.0 11.6 0.6 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.1 31.7 11.4 0.0 0.0 2.6 14.3 38.2 3.7 0.0 0.0 0.0 0.3 3.0 2.5 0.0 0.0 0.0 0.6 0.0 20.4 2.7 HOOK2 HK2 ENSG00000095066 "Hook microtubule tethering protein 2" Q96ED9 19 12763003-12872740 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 291.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 83.7;RT4: 100.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043519, HPA050351" Approved Supported Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 15: RT4 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Vesicles, Cytosol" "HPA043519: AB_2678525, HPA050351: AB_2681102" "unprognostic (4.26e-1)" "unprognostic (3.80e-2)" "unprognostic (2.53e-3)" "unprognostic (1.16e-1)" "unprognostic (4.57e-1)" "unprognostic (1.59e-3)" "unprognostic (1.76e-1)" "unprognostic (6.25e-3)" "unprognostic (3.06e-2)" "unprognostic (2.52e-2)" "unprognostic (1.75e-3)" "prognostic unfavorable (7.59e-5)" "prognostic favorable (3.28e-4)" "unprognostic (3.27e-3)" "unprognostic (5.74e-2)" "unprognostic (1.54e-1)" "unprognostic (2.91e-2)" 40.0 20.6 15.8 10.3 15.1 4.1 45.8 15.5 21.0 31.4 14.3 35.8 52.0 15.1 46.8 55.5 27.0 20.9 63.3 14.8 15.2 54.9 46.8 24.0 7.1 15.3 14.3 24.9 98.1 38.4 113.8 14.2 15.5 53.1 25.0 13.4 59.3 26.8 70.7 56.2 43.1 10.7 12.7 18.0 41.8 24.7 14.8 7.5 96.2 34.0 13.3 25.1 39.3 15.5 38.5 9.7 11.3 8.0 12.5 11.5 40.5 11.9 5.6 6.5 8.3 33.3 44.2 7.5 20.8 11.5 5.7 48.6 12.0 34.3 6.8 19.7 8.8 7.5 21.1 11.0 5.9 4.2 10.2 14.0 32.4 8.3 13.4 15.0 3.9 14.6 12.6 5.7 13.6 83.7 4.3 7.8 4.8 24.9 10.2 12.1 7.1 18.6 13.4 100.5 28.1 14.5 8.7 25.7 7.3 11.5 35.3 9.1 7.2 12.6 8.5 19.7 4.2 20.6 23.9 4.5 13.4 14.2 9.3 0.2 0.8 0.0 1.4 1.3 0.9 1.7 1.8 0.6 1.3 1.2 3.0 1.9 1.0 1.3 0.8 0.6 0.4 1.1 15.8 15.1 15.5 21.0 14.8 15.2 15.3 14.3 15.5 12.7 14.8 15.5 14.8 19.2 38.0 25.1 34.4 50.5 99.8 135.0 158.8 117.7 84.4 62.9 29.6 75.8 84.5 82.8 100.1 85.0 11.9 137.2 43.0 77.5 9.2 26.2 21.0 18.6 63.0 11.1 28.9 45.4 40.2 24.2 140.2 39.3 12.6 30.7 22.1 24.4 16.6 63.9 43.3 93.9 118.0 11.1 21.6 9.1 27.1 20.4 28.4 6.5 19.7 26.6 10.3 17.1 10.6 46.7 98.0 26.7 30.1 131.6 291.7 45.4 49.3 84.5 13.1 24.5 25.4 73.9 26.1 82.1 65.5 128.1 27.9 42.1 95.6 87.1 HOXA2 HOX1K ENSG00000105996 "Homeobox A2" O43364 7 27100354-27102686 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 23.3;Breast myoepithelial cells: 3.8;Enteroendocrine cells: 4.8;Hepatic stellate cells: 6.4;Squamous epithelial cells: 6.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 16 "medulla oblongata: 4.5;pons: 3.3;spinal cord: 4.7;white matter: 4.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 14.5;HaCaT: 6.2;RPTEC TERT1: 4.9" "Region enriched" "Detected in single" 36 "pons and medulla: 5.8" "Group enriched" "Detected in some" 17 "medulla oblongata: 4.2;pons: 1.1;spinal cord: 3.0" HPA078220 Approved Nucleoplasm,Vesicles Yes NA "Cluster 1: Neutrophils - Mixed function" "Cluster 68: Epididymis - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Vesicles" "HPA078220: AB_2686880" "unprognostic (7.30e-2)" "unprognostic (4.90e-4)" "unprognostic (2.81e-1)" "unprognostic (7.43e-4)" "unprognostic (1.44e-1)" "unprognostic (2.01e-2)" "unprognostic (1.17e-1)" "unprognostic (2.96e-1)" "unprognostic (1.85e-3)" "unprognostic (1.48e-2)" "unprognostic (1.84e-1)" "unprognostic (1.58e-2)" "unprognostic (4.98e-9)" "unprognostic (1.34e-1)" "unprognostic (1.33e-1)" "unprognostic (9.36e-2)" "unprognostic (1.28e-2)" 1.9 1.0 0.0 0.6 0.0 0.0 1.6 0.0 0.0 1.6 0.0 3.3 0.9 2.0 5.1 2.3 4.1 1.0 0.2 0.0 0.0 4.4 0.2 1.7 0.2 4.5 0.2 0.6 0.3 5.7 0.0 0.0 3.3 1.7 1.8 0.0 0.0 2.1 0.7 1.6 2.6 0.9 4.7 1.2 2.2 0.1 0.1 1.8 0.8 3.0 0.6 2.0 0.9 4.3 1.1 0.6 4.0 14.5 0.0 0.0 0.0 0.2 0.1 0.0 0.1 1.6 3.4 0.1 1.5 0.1 1.8 6.2 0.2 0.0 0.0 0.0 2.0 0.0 0.1 0.2 1.8 0.1 0.3 0.8 0.0 3.1 3.1 0.0 2.5 0.3 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.9 1.0 0.7 0.0 4.9 0.5 0.9 0.0 0.2 0.0 0.9 0.2 0.0 0.0 2.5 0.0 0.2 1.1 0.5 0.0 0.0 0.1 0.0 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.2 3.3 4.7 0.1 4.3 1.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 23.3 0.0 1.2 3.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.1 1.3 2.5 4.8 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 6.4 0.1 0.1 0.0 0.0 1.3 0.0 0.0 0.7 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.1 1.1 0.5 0.0 0.0 0.0 1.0 1.9 0.0 0.0 6.3 0.3 0.0 0.1 0.0 1.7 0.7 HP ENSG00000257017 Haptoglobin P00738 16 72054505-72061055 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Immunity" "Antibiotic, Antimicrobial, Antioxidant, Serine protease homolog" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 91 "liver: 61113.6" "Cell type enriched" "Detected in many" 43 "Hepatocytes: 59512.7" "Cancer enriched" "Detected in many" 81 "liver cancer: 1297.4" "Region enhanced" "Detected in all" "medulla oblongata: 29.7" "Group enriched" "Detected in many" 5 "classical monocyte: 49.3;eosinophil: 80.2" "Group enriched" "Detected in many" 7 "granulocytes: 80.2;monocytes: 49.3" "Group enriched" "Detected in some" 5 "Hep G2: 232.2;HSkMC: 121.4" "CAB003787, HPA047750, HPA066795" Enhanced Approved Vesicles "Secreted to blood" NA NA 998000000000 100000000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB003787: , HPA047750: AB_2680146, HPA066795: " "unprognostic (6.38e-3)" "unprognostic (7.73e-3)" "unprognostic (1.23e-1)" "unprognostic (2.41e-2)" "unprognostic (2.34e-3)" "unprognostic (2.07e-1)" "unprognostic (7.79e-3)" "unprognostic (1.37e-1)" "unprognostic (2.31e-1)" "unprognostic (1.84e-1)" "unprognostic (6.30e-2)" "unprognostic (8.18e-2)" "prognostic unfavorable (6.94e-13)" "unprognostic (4.34e-4)" "unprognostic (1.80e-1)" "unprognostic (6.61e-2)" "unprognostic (2.49e-2)" 673.1 11.4 1.3 26.9 1.7 231.5 34.2 1.4 2.9 71.9 3.6 3.6 1.5 3.5 2.9 5.3 74.6 1.3 146.7 1.4 1.4 19.8 61113.6 91.3 1.7 29.7 2.0 9.9 7.6 0.2 49.9 2.5 3.7 7.3 0.6 0.7 6.1 0.2 5.0 3.4 4.4 4.5 2.3 72.0 6.2 2.1 8.3 2.7 6.3 0.4 3.0 3.8 3.3 5.9 0.0 0.0 0.0 0.0 6.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 8.5 0.3 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 11.2 0.2 232.2 0.3 33.3 6.2 121.4 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 2.0 0.4 2.6 0.0 0.0 1.1 23.6 0.0 0.0 0.1 0.0 0.0 16.2 0.0 0.0 0.0 0.0 6.8 5.1 0.0 0.8 0.0 0.0 3.9 0.0 14.1 0.0 12.7 0.0 6.2 49.3 80.2 0.0 2.0 0.0 0.0 0.0 0.0 8.7 0.0 0.0 0.0 14.2 0.0 2.1 0.0 0.0 15.2 1.3 1.7 1.4 2.9 1.4 1.4 29.7 2.0 3.7 2.3 8.3 5.9 0.4 19.2 228.7 1.6 96.1 0.1 0.7 1.9 0.0 0.4 0.4 0.3 66.6 1085.2 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 56.7 0.0 1128.3 0.0 10.4 0.1 45.5 0.0 1.3 3.8 0.4 1038.7 59512.7 2.3 0.0 0.0 0.2 4.1 1381.4 0.0 0.5 10.2 7.8 1.8 0.0 0.3 1.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.8 0.0 1.5 7.5 0.2 0.0 2.6 1.8 0.0 0.0 0.1 0.3 0.1 90.3 0.0 0.3 0.1 HPGDS "GSTS, GSTS1, GSTS1-1, H-PGDS, PGD2, PGDS" ENSG00000163106 "Hematopoietic prostaglandin D synthase" O60760 4 94298535-94342876 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 18.7" "Group enriched" "Detected in many" 18 "granulocytes: 1056.2;Hofbauer cells: 631.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "basophil: 18.1" "Lineage enriched" "Detected in single" 28 "granulocytes: 18.1" "Group enriched" "Detected in some" 8 "HEL: 46.2;HMC-1: 13.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA024035 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 250000 "Cluster 46: Basophils - DNA binding" "Cluster 19: Lung - Lung function" "Cluster 36: HEL - Hemostasis" "Cluster 60: Granulocytes - Receptor signaling" "Vesicles, Cytosol" Nucleoplasm "HPA024035: AB_1855743" "unprognostic (5.71e-2)" "unprognostic (5.80e-3)" "unprognostic (1.17e-1)" "unprognostic (5.36e-3)" "unprognostic (2.76e-1)" "unprognostic (2.38e-4)" "unprognostic (1.01e-2)" "unprognostic (4.41e-3)" "unprognostic (1.35e-1)" "unprognostic (7.75e-4)" "unprognostic (1.44e-1)" "unprognostic (1.14e-1)" "unprognostic (5.15e-3)" "unprognostic (4.07e-2)" "unprognostic (6.48e-2)" "unprognostic (2.61e-2)" "unprognostic (6.14e-2)" 3.4 1.9 2.2 1.1 2.1 1.1 4.0 2.3 3.1 3.5 2.1 5.1 5.8 2.4 2.3 2.9 1.4 6.9 1.8 2.3 2.3 1.5 0.8 9.4 0.6 2.7 2.6 0.5 0.5 0.8 0.4 18.7 2.9 2.6 5.3 0.1 1.5 1.3 0.5 3.3 5.6 3.3 2.6 0.3 2.8 0.7 3.1 2.0 0.3 1.7 0.9 4.8 1.2 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.2 0.0 0.0 0.0 3.5 13.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.1 0.1 0.3 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 2.2 2.1 2.3 3.1 2.3 2.3 2.7 2.6 2.9 2.6 3.1 3.5 0.3 12.8 44.7 1.0 0.2 4.1 0.8 0.0 0.6 0.0 0.2 0.8 0.3 0.0 3.7 0.0 0.0 3.6 0.7 0.5 0.0 0.5 0.1 0.2 0.0 2.0 7.1 12.2 0.8 0.0 3.0 3.0 3.6 0.0 1056.2 0.0 0.0 0.0 631.9 0.0 0.6 0.0 0.0 11.4 13.1 0.0 0.3 16.3 3.6 32.8 0.1 0.0 0.0 0.0 0.5 0.1 1.2 0.4 2.1 3.9 0.0 0.0 1.5 0.1 0.0 0.6 0.4 0.0 0.1 0.0 5.4 5.5 20.5 0.3 0.9 0.2 HPR ENSG00000261701 "Haptoglobin-related protein" P00739 16 72063148-72077246 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 811.9" "Group enriched" "Detected in some" 14 "Hepatocytes: 503.0;Smooth muscle cells: 128.8" "Cancer enriched" "Detected in some" 53 "liver cancer: 185.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "Hep G2: 50.6" HPA047750 Supported Approved Vesicles "Secreted to blood" NA NA 49000000000 55000000000 "Cluster 35: T-regs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA047750: AB_2680146" "unprognostic (2.43e-1)" "unprognostic (4.69e-2)" "unprognostic (5.97e-3)" "unprognostic (2.42e-1)" "unprognostic (2.32e-3)" "unprognostic (2.36e-1)" "unprognostic (1.66e-1)" "unprognostic (8.21e-2)" "unprognostic (2.30e-1)" "unprognostic (3.44e-6)" "unprognostic (2.09e-2)" "unprognostic (1.45e-1)" "unprognostic (1.29e-1)" 5.5 0.5 14.1 0.2 15.3 0.1 2.0 13.9 16.7 1.2 11.3 1.2 0.6 0.3 0.4 0.3 1.3 0.7 137.2 13.7 14.3 4.0 811.9 1.5 0.7 14.4 14.3 2.0 0.6 0.0 0.3 0.0 13.6 1.6 0.1 0.8 0.3 0.3 1.7 0.6 1.1 0.1 12.8 0.3 1.7 1.9 15.2 0.2 1.1 0.2 0.1 0.4 1.9 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.6 2.2 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.1 0.1 0.1 0.0 0.2 0.4 0.2 0.0 0.1 0.0 0.6 0.6 0.0 14.1 15.3 13.9 16.7 13.7 14.3 14.4 14.3 13.6 12.8 15.2 13.1 0.0 0.0 7.5 2.3 0.4 0.1 0.0 0.9 0.0 0.1 0.0 0.0 22.4 12.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.8 0.0 5.3 0.2 0.2 0.0 2.6 0.0 0.0 0.0 1.1 10.8 503.0 0.0 0.0 0.2 0.0 2.0 12.8 0.0 2.8 9.9 0.0 0.0 0.0 0.0 4.9 0.0 0.0 1.2 0.0 0.0 5.3 0.0 0.0 0.0 13.0 0.2 0.1 0.0 6.1 128.8 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.2 0.0 HPSE "HPA, HPSE1, HSE1" ENSG00000173083 Heparanase Q9Y251 4 83292461-83335153 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Cell adhesion" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 16.4;Kupffer cells: 41.5;Macrophages: 20.2;monocytes: 33.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "classical monocyte: 27.2;neutrophil: 18.5" "Group enriched" "Detected in many" 4 "granulocytes: 18.5;monocytes: 27.2" "Cell line enhanced" "Detected in many" "Karpas-707: 39.8;OE19: 40.1;TIME: 25.8" "Region enhanced" "Detected in some" "olfactory bulb: 3.7" "Low region specificity" "Detected in all" "CAB009813, HPA055344" Supported Nucleoplasm,Vesicles "Secreted to extracellular matrix" No No 6500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 2: Karpas-707 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm Vesicles "CAB009813: AB_2120854, HPA055344: " "unprognostic (6.57e-2)" "unprognostic (1.22e-2)" "unprognostic (9.13e-2)" "unprognostic (5.92e-3)" "unprognostic (1.12e-1)" "unprognostic (1.25e-1)" "unprognostic (1.24e-2)" "unprognostic (5.65e-2)" "unprognostic (7.06e-2)" "unprognostic (1.90e-1)" "unprognostic (1.50e-1)" "unprognostic (9.62e-3)" "unprognostic (3.27e-1)" "unprognostic (2.78e-1)" "unprognostic (3.04e-3)" "unprognostic (4.15e-2)" "unprognostic (3.70e-3)" 3.4 4.5 0.8 6.6 0.9 2.3 1.0 0.6 1.7 2.4 0.4 5.9 2.1 2.7 0.2 9.9 3.9 2.7 0.8 0.9 0.9 1.6 2.4 3.2 4.5 1.8 1.0 4.5 0.8 5.6 1.2 2.1 1.3 0.6 6.4 0.2 9.7 0.6 0.3 5.3 2.8 1.9 1.8 6.0 2.0 5.7 2.7 2.0 0.7 0.3 3.9 3.0 3.3 3.6 13.5 0.6 0.1 1.7 3.2 0.9 0.1 1.5 8.2 3.6 16.5 0.0 11.0 0.4 2.3 4.2 20.8 12.3 16.8 2.5 6.5 1.4 1.7 4.2 9.0 0.2 1.4 2.5 8.4 1.8 5.1 2.4 15.4 1.4 18.1 2.4 0.1 39.8 1.5 2.8 0.2 0.3 0.7 40.1 2.6 0.0 0.4 0.6 10.2 0.3 9.3 0.0 17.7 9.8 1.4 2.6 1.5 3.8 25.8 1.5 4.6 1.4 1.7 0.5 6.2 0.2 9.9 11.4 2.7 0.4 27.2 0.0 1.4 10.1 1.0 0.2 2.7 1.0 3.0 0.3 1.7 1.6 18.5 2.3 1.5 0.1 5.2 7.9 0.8 0.9 0.6 1.7 0.9 0.9 1.8 1.0 1.3 1.8 2.7 3.6 0.3 6.4 4.4 0.0 0.7 3.4 3.0 3.3 2.8 0.0 0.3 0.5 0.6 0.0 5.6 1.8 0.0 0.5 2.4 10.1 0.0 1.9 0.6 2.3 3.7 1.0 6.6 2.7 0.8 1.3 2.9 1.4 4.1 13.2 0.0 0.4 2.9 0.6 16.4 0.0 3.8 2.8 0.0 41.5 3.0 0.3 0.6 20.2 0.0 7.5 33.9 0.0 3.1 0.0 0.1 1.1 6.7 0.0 0.7 1.7 4.1 0.0 2.8 0.0 0.0 0.1 1.2 0.2 1.0 4.0 3.7 1.5 6.2 1.4 4.6 3.7 HS3ST1 3OST1 ENSG00000002587 "Heparan sulfate-glucosamine 3-sulfotransferase 1" O14792 4 11393150-11429564 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.4;ovary: 31.9" "Cell type enhanced" "Detected in many" "Club cells: 112.0;granulocytes: 96.3;Granulosa cells: 285.0;Peritubular cells: 90.3;Urothelial cells: 92.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 25.4" "Group enriched" "Detected in some" 36 "memory B-cell: 14.9;naive B-cell: 26.6;plasmacytoid DC: 42.3" "Group enriched" "Detected in many" 108 "B-cells: 26.6;dendritic cells: 42.3" "Cell line enhanced" "Detected in some" "A-431: 5.8;CAPAN-2: 20.6;HaCaT: 6.0;RPTEC TERT1: 13.2;RT4: 14.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002237 Approved Approved Vesicles "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA002237: AB_1079085" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (4.01e-2)" "prognostic favorable (7.73e-4)" "unprognostic (3.32e-2)" "unprognostic (8.90e-3)" "unprognostic (4.21e-1)" "unprognostic (2.08e-1)" "unprognostic (2.22e-1)" "unprognostic (1.32e-1)" "unprognostic (1.77e-2)" "unprognostic (1.08e-1)" "prognostic favorable (5.99e-8)" "unprognostic (9.99e-2)" "unprognostic (1.42e-1)" "unprognostic (1.57e-1)" "prognostic favorable (8.67e-4)" 2.6 2.5 2.3 2.7 1.9 2.0 1.9 25.4 6.9 2.4 0.0 2.1 3.7 3.4 1.3 11.6 4.4 12.7 1.9 1.6 4.7 5.9 0.4 1.8 2.3 4.7 3.3 31.9 1.0 0.1 4.7 0.7 3.8 2.0 1.1 1.0 5.6 1.5 0.4 0.5 2.9 0.9 4.4 3.3 6.5 1.3 5.8 1.3 1.6 0.2 1.2 14.5 2.6 6.1 5.8 1.8 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 20.6 0.0 0.4 0.0 0.0 6.0 0.0 2.8 0.0 0.3 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.8 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.1 1.6 2.2 1.2 0.0 0.0 13.2 14.5 4.6 0.0 0.0 0.1 0.4 0.2 0.0 0.0 2.0 0.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.2 14.9 0.0 0.0 0.7 26.6 0.0 0.0 0.0 0.0 0.0 42.3 0.0 1.1 2.3 1.9 25.4 6.9 1.6 4.7 4.7 3.3 3.8 4.4 5.8 6.1 3.5 3.2 5.8 0.0 13.1 9.1 13.5 70.1 5.2 3.7 2.4 9.3 3.2 32.9 112.0 20.2 4.2 0.5 21.6 5.2 0.0 25.0 1.7 3.6 1.0 28.9 2.4 0.0 13.4 2.1 42.1 13.2 23.9 14.9 96.3 285.0 25.0 0.4 37.6 1.7 35.0 7.2 71.2 3.5 3.7 2.0 8.7 12.5 1.8 6.5 4.9 32.9 8.2 24.1 0.7 51.9 6.5 90.3 0.0 5.6 2.7 19.1 61.2 2.6 0.0 0.5 17.5 5.4 5.6 36.6 8.1 1.4 1.4 68.5 4.3 92.9 HS3ST3B1 "30ST3B1, 3OST3B1" ENSG00000125430 "Heparan sulfate-glucosamine 3-sulfotransferase 3B1" Q9Y662 17 14301081-14349404 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 28.4;retina: 11.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 39.6;dendritic cells: 32.5;Hepatic stellate cells: 25.7;Hepatocytes: 39.7;Syncytiotrophoblasts: 36.3" "Cancer enhanced" "Detected in many" "liver cancer: 5.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 35.1" "Group enriched" "Detected in many" 5 "dendritic cells: 35.1;T-cells: 26.2" "Cell line enhanced" "Detected in many" "AF22: 20.7;BEWO: 14.9;Hep G2: 18.8;HSkMC: 20.2;U-251 MG: 19.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" HPA064126 Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA064126: AB_2685194" "unprognostic (1.74e-1)" "unprognostic (1.13e-1)" "unprognostic (2.29e-2)" "unprognostic (5.55e-3)" "unprognostic (2.85e-3)" "unprognostic (5.22e-2)" "unprognostic (5.03e-3)" "unprognostic (1.79e-1)" "unprognostic (2.93e-1)" "unprognostic (8.13e-3)" "unprognostic (8.80e-2)" "unprognostic (1.13e-1)" "unprognostic (1.02e-3)" "unprognostic (7.77e-3)" "unprognostic (9.46e-2)" "unprognostic (1.91e-1)" "unprognostic (1.54e-3)" 0.9 0.9 0.2 4.6 1.0 1.4 0.9 0.3 1.3 2.4 1.5 1.2 1.3 0.6 0.2 1.8 0.9 1.4 1.5 0.4 0.4 3.0 28.4 1.6 6.3 5.4 2.5 3.5 0.6 0.3 0.7 3.5 2.0 2.0 1.7 11.5 5.3 2.0 1.0 1.5 1.8 0.5 2.9 3.4 1.2 0.4 1.4 3.2 0.7 0.9 4.8 2.6 1.9 0.9 0.0 0.4 20.7 0.0 6.2 6.9 14.9 6.1 8.7 5.3 5.6 0.0 0.1 0.0 0.0 8.2 0.0 0.1 0.5 3.3 2.7 1.8 4.5 0.5 2.9 18.8 8.1 0.8 3.2 20.2 1.1 1.9 4.8 1.2 0.0 1.1 6.6 0.1 4.3 1.1 1.0 0.8 0.7 0.1 0.6 3.9 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 2.8 0.4 0.6 0.0 5.2 0.0 0.1 19.9 0.0 0.0 0.0 4.0 0.0 1.2 0.2 0.4 0.0 10.2 0.7 8.1 0.9 12.0 8.0 0.8 0.7 12.1 11.8 0.9 6.6 0.8 35.1 26.2 5.1 0.2 1.0 0.3 1.3 0.4 0.4 5.4 2.5 2.0 2.9 1.4 0.9 2.9 0.0 1.1 6.2 3.5 11.5 0.3 4.9 21.1 3.2 1.2 2.2 3.0 10.0 3.9 7.3 39.6 7.2 32.5 0.0 0.0 0.7 14.3 0.3 1.5 2.9 0.0 0.4 3.3 0.2 11.9 6.6 0.0 0.8 0.0 2.4 25.7 39.7 1.6 8.4 2.2 0.1 2.0 3.8 12.9 3.3 2.8 6.7 1.8 1.9 1.3 7.3 14.4 3.5 0.1 0.2 0.0 1.2 2.2 1.1 0.4 0.1 3.9 17.9 13.1 15.0 2.6 4.0 0.3 10.0 14.8 36.3 12.4 0.1 0.2 0.3 HSD11B1L "HSD1L, SCDR10, SDR26C2" ENSG00000167733 "Hydroxysteroid 11-beta dehydrogenase 1 like" Q7Z5J1 19 5680604-5688523 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 58.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SH-SY5Y: 19.0" "Low region specificity" "Detected in all" HPA049078 Supported Vesicles "Secreted in brain" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA049078: AB_2680622" "unprognostic (2.34e-2)" "unprognostic (1.10e-1)" "unprognostic (4.73e-3)" "unprognostic (5.26e-2)" "unprognostic (9.37e-2)" "prognostic favorable (4.38e-4)" "unprognostic (4.81e-3)" "unprognostic (6.63e-3)" "unprognostic (2.63e-1)" "unprognostic (2.47e-1)" "unprognostic (1.18e-3)" "unprognostic (1.43e-1)" "unprognostic (3.33e-2)" "unprognostic (1.75e-1)" "unprognostic (5.77e-2)" "unprognostic (4.52e-1)" "unprognostic (1.73e-2)" 3.9 9.8 46.6 1.3 46.7 2.6 5.1 32.0 58.2 5.5 34.0 8.4 1.6 5.4 5.1 3.7 6.7 3.0 5.9 46.1 41.8 12.4 5.4 4.4 1.4 38.4 36.5 6.7 7.0 7.3 21.2 1.5 37.2 6.1 1.0 6.3 5.8 4.1 10.9 9.3 3.4 1.6 32.9 3.2 6.3 8.1 42.4 1.6 8.6 3.3 1.0 6.0 4.3 39.1 3.6 3.0 11.3 2.1 5.0 5.7 2.2 2.7 4.4 1.1 4.8 1.3 3.3 0.8 5.9 2.2 0.9 1.7 1.4 1.8 1.0 3.2 3.6 2.3 3.0 2.2 3.6 0.9 7.9 5.5 3.9 1.6 1.6 10.4 1.8 5.1 2.4 2.9 4.6 0.3 2.1 2.1 3.0 14.2 4.1 3.6 0.5 3.1 9.5 0.8 3.2 19.0 0.5 1.6 12.8 3.8 2.6 0.7 3.2 2.7 5.0 4.9 2.2 7.6 2.8 0.9 7.7 1.2 2.4 1.5 1.0 0.5 0.6 2.7 0.6 0.5 1.4 1.6 1.0 1.1 1.8 1.7 1.9 0.7 1.8 2.2 0.4 0.9 46.6 46.7 32.0 58.2 46.1 41.8 38.4 36.5 37.2 32.9 42.4 39.1 8.2 0.0 2.6 13.7 2.6 8.2 8.6 12.9 9.6 11.3 23.7 23.1 2.3 10.0 8.6 23.9 14.6 4.7 3.0 4.5 15.6 12.4 9.5 21.8 6.0 6.1 25.7 1.3 24.7 4.7 6.5 8.1 4.6 5.4 10.2 12.4 8.9 4.1 5.1 8.4 20.4 4.6 12.2 2.8 6.0 13.9 7.2 2.4 5.4 1.9 3.1 30.5 1.0 14.1 4.6 4.8 4.3 12.8 0.9 8.4 4.1 33.3 31.2 12.9 0.0 8.1 9.5 10.8 12.7 4.8 10.2 2.9 3.1 16.6 3.7 9.7 HSD17B13 "SCDR9, SDR16C3" ENSG00000170509 "Hydroxysteroid 17-beta dehydrogenase 13" Q7Z5P4 4 87303789-87322886 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 61 "liver: 573.7" "Cell type enhanced" "Detected in many" "Adipocytes: 100.0;Club cells: 42.9;Hepatocytes: 131.3;Respiratory ciliated cells: 34.0;Urothelial cells: 57.0" "Cancer enriched" "Detected in some" 26 "liver cancer: 52.9" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in single" "NB-4: 1.4" "Not detected" "Not detected" HPA029125 Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 37: B-cells - Transcription" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 24: NB-4 - Immune response" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Golgi apparatus" "HPA029125: AB_10601580" "unprognostic (2.49e-1)" "unprognostic (7.46e-2)" "unprognostic (7.02e-2)" "unprognostic (1.86e-4)" "unprognostic (4.74e-2)" "unprognostic (8.44e-2)" "prognostic favorable (2.94e-4)" "prognostic favorable (7.80e-4)" "unprognostic (4.97e-1)" "unprognostic (2.22e-2)" "unprognostic (1.00e-1)" "unprognostic (2.46e-1)" "unprognostic (7.18e-4)" "unprognostic (3.62e-1)" "unprognostic (1.01e-1)" "unprognostic (1.03e-1)" "unprognostic (1.52e-3)" 9.4 0.3 0.6 0.2 0.6 1.4 6.4 2.4 1.0 2.7 0.1 0.7 0.4 2.7 0.2 0.2 1.0 0.2 0.4 0.6 0.5 0.4 573.7 3.6 0.2 0.8 0.5 0.5 1.8 0.1 0.2 0.8 0.9 4.5 0.4 0.8 0.2 0.2 0.3 6.5 0.7 4.2 0.4 0.7 0.3 0.4 0.5 0.3 0.2 0.1 0.1 1.2 7.8 0.9 0.0 0.1 0.2 0.2 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.3 0.4 0.2 0.7 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.2 0.2 0.2 0.1 0.0 0.1 1.4 0.1 0.4 0.1 0.2 0.2 0.1 0.0 0.1 0.1 0.5 0.1 0.1 0.0 0.1 0.0 0.4 0.2 0.1 0.7 0.1 0.1 0.1 0.1 0.1 0.0 0.5 0.2 1.0 0.1 0.4 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.2 0.2 0.1 0.6 0.1 0.0 0.1 0.1 0.0 0.6 0.6 2.4 1.0 0.6 0.5 0.8 0.5 0.9 0.4 0.5 0.9 100.0 3.2 6.4 1.6 0.0 2.5 22.6 0.3 0.0 0.2 0.2 0.3 0.3 4.3 42.9 1.8 0.0 0.1 0.4 1.0 0.0 0.1 2.7 0.4 0.5 2.4 1.8 5.3 3.7 0.4 0.3 0.8 0.0 0.1 0.0 0.2 1.8 131.3 0.2 0.0 3.0 0.5 0.0 2.4 0.4 2.7 0.0 0.7 0.0 0.0 0.3 0.3 0.0 1.5 2.8 0.1 1.4 0.4 0.1 4.7 0.2 0.5 34.0 0.1 0.0 0.7 0.4 0.0 0.9 0.2 0.4 0.0 0.7 0.2 0.7 57.0 HSD17B3 SDR12C2 ENSG00000130948 "Hydroxysteroid 17-beta dehydrogenase 3" P37058 9 96235306-96302176 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Disease variant, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 15.1;testis: 36.7" "Group enriched" "Detected in some" 6 "Leydig cells: 108.1;Oligodendrocytes: 93.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HBEC3-KT: 2.3;HEL: 1.0;U-2 OS: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA056833 Enhanced Approved Vesicles NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA056833: AB_2683252" "unprognostic (2.78e-1)" "unprognostic (6.61e-3)" "unprognostic (1.03e-1)" "unprognostic (5.76e-2)" "unprognostic (1.15e-1)" "unprognostic (1.55e-1)" "unprognostic (3.08e-2)" "unprognostic (6.15e-2)" "unprognostic (1.74e-1)" "unprognostic (5.13e-2)" "unprognostic (3.26e-4)" "unprognostic (3.45e-1)" "unprognostic (5.48e-8)" "unprognostic (8.47e-3)" "unprognostic (1.15e-1)" "unprognostic (7.24e-2)" "unprognostic (3.11e-2)" 1.6 0.8 3.1 0.2 4.3 0.0 1.7 3.4 5.9 3.1 2.4 2.7 0.5 1.5 0.9 0.7 3.5 0.2 2.1 3.1 3.6 4.7 15.1 1.8 0.0 4.3 3.9 1.4 4.2 0.0 1.7 0.1 4.2 3.2 0.1 0.7 1.0 0.1 0.5 0.9 3.7 0.0 3.3 0.9 1.4 36.7 4.2 0.1 10.0 0.1 0.0 1.6 1.8 5.4 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.3 0.0 0.0 0.0 1.0 0.0 0.1 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.1 4.3 3.4 5.9 3.1 3.6 4.3 3.9 4.2 3.3 4.2 5.4 0.0 0.0 0.0 15.3 0.2 0.0 0.1 0.8 0.0 0.2 0.1 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.2 4.0 0.2 0.0 0.4 1.8 0.0 0.5 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.0 2.5 0.0 0.0 0.5 0.5 0.0 0.0 0.4 14.4 108.1 1.1 0.0 4.7 0.1 0.6 0.0 1.0 93.2 0.2 0.1 12.8 0.0 0.1 0.6 0.0 0.5 0.2 0.0 0.1 0.5 1.9 1.8 0.0 0.3 0.1 0.0 0.0 0.3 0.0 HSD17B6 "HSE, RODH, SDR9C6" ENSG00000025423 "Hydroxysteroid 17-beta dehydrogenase 6" O14756 12 56752161-56787790 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "liver: 1804.3" "Cell type enriched" "Detected in many" 11 "Hepatocytes: 1969.3" "Cancer enriched" "Detected in many" 5 "liver cancer: 170.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 13.4;U-266/84: 18.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059141 Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 16: U-266 - Nucleosome" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Vesicles" "HPA059141: AB_2683922" "unprognostic (7.70e-2)" "unprognostic (8.76e-2)" "unprognostic (5.08e-2)" "unprognostic (1.92e-2)" "unprognostic (2.01e-1)" "unprognostic (3.79e-2)" "prognostic favorable (6.32e-4)" "unprognostic (1.06e-2)" "unprognostic (3.21e-1)" "unprognostic (1.44e-1)" "unprognostic (1.35e-1)" "unprognostic (6.74e-2)" "unprognostic (2.50e-10)" "unprognostic (1.26e-1)" "unprognostic (1.79e-1)" "unprognostic (1.08e-1)" "unprognostic (1.05e-1)" 8.5 2.5 13.1 6.9 16.2 0.5 0.7 13.4 18.9 28.0 9.4 24.7 3.2 20.9 1.6 9.9 6.5 9.1 0.8 12.3 12.6 2.5 1804.3 63.2 0.8 12.0 14.6 6.0 0.6 0.5 0.6 5.4 11.5 51.2 7.6 0.8 0.4 69.2 0.4 1.2 4.8 13.1 12.4 47.5 5.7 23.3 13.7 0.9 31.4 0.5 0.9 36.7 14.6 12.8 0.3 0.8 1.9 0.4 1.9 1.4 2.3 4.1 3.5 1.9 1.9 0.4 0.4 12.0 1.7 0.5 0.5 0.3 6.1 1.1 1.1 7.7 2.2 3.7 1.2 0.6 1.2 1.9 6.0 1.0 0.4 1.2 0.6 0.6 0.0 10.3 1.1 13.4 0.9 2.4 5.6 1.3 7.5 0.7 0.7 7.4 0.8 2.9 0.2 1.4 11.0 2.3 2.0 3.6 0.9 0.7 0.6 1.5 0.3 0.9 0.8 4.0 1.0 11.7 18.0 7.8 1.3 6.9 0.6 0.0 0.0 0.0 1.0 0.2 1.2 0.7 0.8 0.8 0.2 0.3 1.1 0.7 0.0 0.0 0.5 0.7 1.0 0.3 13.1 16.2 13.4 18.9 12.3 12.6 12.0 14.6 11.5 12.4 13.7 12.8 0.4 173.1 130.6 21.2 6.1 1.3 3.1 0.6 0.6 0.4 0.7 0.6 0.2 27.1 9.3 0.0 0.0 1.4 0.4 0.0 0.0 0.1 4.6 0.7 3.5 1.3 0.0 29.5 1.4 0.0 2.6 5.0 0.0 0.1 0.0 1.6 26.0 1969.3 0.4 0.0 2.1 0.4 0.0 40.2 0.3 4.5 12.5 0.5 0.0 1.0 1.0 1.3 0.0 3.0 5.5 0.1 0.0 1.5 0.8 16.1 0.0 0.3 1.5 0.6 13.1 0.6 3.5 16.4 11.4 1.2 1.6 0.4 2.2 36.0 0.7 1.1 HSDL1 SDR12C3 ENSG00000103160 "Hydroxysteroid dehydrogenase like 1" Q3SXM5 16 84122141-84145192 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Horizontal cells: 45.4;Rod photoreceptor cells: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045745 Supported "Vesicles,Intermediate filaments,Mitochondria" No No "Cluster 34: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 40: Granulosa cells - Unknown function" Mitochondria "Vesicles, Intermediate filaments" "HPA045745: AB_2679440" "unprognostic (2.16e-1)" "unprognostic (4.32e-2)" "unprognostic (2.09e-1)" "unprognostic (4.80e-3)" "unprognostic (3.66e-2)" "unprognostic (1.68e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (1.25e-2)" "unprognostic (7.43e-2)" "unprognostic (3.39e-2)" "unprognostic (6.42e-2)" "unprognostic (3.66e-1)" "prognostic favorable (4.20e-7)" "unprognostic (2.30e-1)" "unprognostic (1.57e-1)" "unprognostic (1.03e-2)" "unprognostic (1.14e-2)" 7.5 15.4 14.3 7.1 14.6 4.4 11.9 10.9 13.0 10.6 10.7 7.4 6.2 13.2 10.5 7.8 12.6 7.1 15.7 14.0 18.3 10.8 5.1 9.1 9.0 15.0 14.8 22.0 4.9 15.1 11.9 9.1 18.6 9.8 6.9 34.3 7.3 11.1 20.7 8.0 5.7 10.8 9.5 8.0 6.4 13.2 17.0 14.1 26.8 30.5 9.2 7.3 7.1 10.2 11.1 12.6 57.4 19.8 20.7 14.5 14.6 13.8 13.1 17.0 8.9 14.5 18.8 22.7 24.7 12.4 18.8 7.6 31.1 12.1 26.9 4.9 18.9 10.9 7.9 32.5 21.0 17.1 19.2 11.0 20.0 24.1 15.4 21.9 20.9 30.6 23.0 28.2 34.3 27.3 37.8 17.4 29.5 6.4 13.3 36.7 20.4 8.4 16.6 12.0 27.1 20.2 35.0 5.6 39.0 28.5 34.4 10.2 17.5 19.2 22.9 13.9 11.3 44.1 38.1 36.9 22.8 12.3 18.2 21.2 5.0 11.1 3.8 3.4 5.0 5.0 4.1 4.6 2.8 7.5 5.3 5.6 5.5 4.3 6.3 0.0 5.4 4.4 14.3 14.6 10.9 13.0 14.0 18.3 15.0 14.8 18.6 9.5 17.0 10.2 8.9 12.8 16.4 7.8 8.2 4.8 4.6 6.4 8.6 20.2 10.2 8.3 16.7 1.5 8.6 3.7 14.6 6.9 4.4 3.7 5.9 7.9 38.5 11.4 10.5 7.7 9.5 5.7 12.4 6.7 6.6 7.7 3.6 11.0 1.3 38.6 9.3 4.1 12.2 45.4 15.8 3.7 4.1 6.9 3.5 12.2 5.9 10.4 5.4 11.2 6.1 28.4 5.2 15.6 13.0 6.8 2.5 10.1 10.1 5.2 3.9 8.0 13.7 44.2 0.0 8.0 7.8 35.8 30.1 8.8 7.0 8.8 6.6 12.7 4.5 4.8 HSPA1A "HSP70-1, HSPA1" ENSG00000204389 "Heat shock protein family A (Hsp70) member 1A" P0DMV8 6 31815543-31817946 "Disease related genes, Predicted intracellular proteins" "Host-virus interaction, Stress response" "Chaperone, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 7514.5;Langerhans cells: 2690.4;Urothelial cells: 3444.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 64 "cerebral cortex: 403.6" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 6.8;monocytes: 3.6;T-cells: 3.0" "Cell line enriched" "Detected in some" 8 "HEK 293: 4450.4" "CAB017451, CAB032815, HPA052504" Supported Approved Nucleoplasm,Vesicles,Cytosol "Intracellular and membrane" NA Yes 47000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Vesicles" Cytosol "CAB017451: AB_10013742, CAB032815: AB_627759, HPA052504: AB_2681854" "unprognostic (2.44e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (1.54e-5)" "unprognostic (6.86e-2)" "unprognostic (2.01e-1)" "unprognostic (1.98e-1)" "unprognostic (1.18e-2)" "unprognostic (6.17e-3)" "unprognostic (2.47e-2)" "unprognostic (1.74e-2)" "unprognostic (8.43e-3)" "unprognostic (1.43e-1)" "unprognostic (1.47e-1)" "unprognostic (2.38e-1)" "unprognostic (6.48e-2)" "unprognostic (4.12e-2)" "unprognostic (1.51e-1)" 640.5 350.5 3.5 12.7 3.8 0.0 167.2 6.3 403.6 414.1 3.4 497.7 0.0 209.7 15.9 452.9 194.6 5.9 927.7 4.3 3.7 745.9 1116.2 1055.0 9.1 5.4 5.1 369.7 308.2 1.1 474.3 12.0 4.0 427.7 4.2 6.5 111.5 0.5 294.4 257.3 174.4 2.2 3.8 451.9 483.2 98.0 3.7 2.5 340.2 0.3 2.3 569.2 553.7 6.1 0.2 524.1 0.0 0.1 20.1 14.4 0.0 0.3 0.0 0.0 0.0 1.6 0.7 0.0 122.9 28.7 0.0 0.4 0.0 34.1 0.0 6.9 4450.4 0.0 1.7 3.1 0.0 1.1 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.0 1.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 33.4 0.0 0.5 0.7 0.0 0.0 16.6 5.3 0.0 0.1 4.1 0.0 49.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.3 2.3 3.2 1.1 3.6 0.7 0.6 1.6 1.4 0.3 0.2 0.7 0.6 6.8 0.8 2.0 0.3 3.0 0.4 3.5 3.8 6.3 403.6 4.3 3.7 5.4 5.1 4.0 3.8 3.7 6.1 1537.0 147.4 97.0 427.4 312.4 362.4 7514.5 125.5 968.7 305.3 782.0 844.3 1010.7 81.5 109.3 126.9 379.5 43.2 148.1 634.6 41.1 86.8 81.0 534.7 488.1 1049.0 469.2 64.0 9.7 21.6 154.1 1208.6 592.8 753.4 445.4 18.1 123.5 95.2 270.4 205.3 11.4 560.1 114.0 319.0 2690.4 49.5 603.0 1715.2 839.6 398.2 126.6 768.2 15.5 17.1 207.0 39.5 668.8 160.6 1173.3 1404.1 68.4 72.9 177.2 690.2 151.2 443.4 1802.0 65.4 148.8 1105.8 336.3 104.3 1382.2 285.6 454.9 3444.4 HSPA1B HSP70-2 ENSG00000204388 "Heat shock protein family A (Hsp70) member 1B" P0DMV9 6 31827738-31830254 "Predicted intracellular proteins" "Host-virus interaction, Stress response" "Chaperone, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 3007.4;Urothelial cells: 1619.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "Karpas-707: 204.3" "CAB008640, HPA052504" Approved Approved Nucleoplasm,Vesicles,Cytosol NA Yes "Cluster 18: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Cytosol" Nucleoplasm "CAB008640: AB_1617331, HPA052504: AB_2681854" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (4.23e-3)" "unprognostic (3.23e-2)" "unprognostic (3.54e-1)" "unprognostic (1.15e-1)" "unprognostic (2.76e-3)" "unprognostic (9.50e-2)" "unprognostic (3.45e-1)" "unprognostic (4.42e-2)" "unprognostic (6.92e-2)" "unprognostic (4.88e-2)" "unprognostic (5.74e-2)" "unprognostic (1.15e-1)" "unprognostic (9.17e-3)" "unprognostic (4.69e-2)" "unprognostic (5.99e-2)" 526.3 340.1 0.7 0.4 1.3 0.0 126.0 1.6 5.6 475.3 0.6 361.2 0.0 154.0 9.1 375.2 231.5 2.3 718.3 1.1 1.9 555.5 685.4 845.3 0.0 0.8 1.0 682.2 336.5 3.3 438.2 0.0 1.2 303.6 0.5 2.6 94.8 0.3 159.9 299.0 139.1 0.0 0.4 274.7 372.0 93.8 1.5 0.0 289.9 0.0 0.0 415.3 503.3 1.2 0.4 24.1 0.4 0.2 1.1 0.0 0.3 0.2 0.0 0.0 0.0 1.0 0.1 0.0 8.4 0.0 0.0 3.3 0.0 0.0 0.0 0.0 15.4 0.0 0.5 2.2 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 204.3 0.0 3.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.5 0.0 1.7 0.0 1.6 0.0 0.0 0.3 3.2 0.0 0.4 41.5 0.4 0.4 0.4 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 1.3 1.6 5.6 1.1 1.9 0.8 1.0 1.2 0.4 1.5 1.2 563.2 112.2 75.0 140.7 242.7 239.2 3007.4 63.2 630.0 44.6 509.4 403.9 512.3 40.0 73.7 69.9 131.3 82.7 82.8 542.8 19.6 45.5 1.9 434.9 380.2 446.2 318.6 57.9 2.7 15.6 140.8 585.8 595.8 710.4 346.8 14.1 25.7 17.7 142.0 47.1 2.8 426.3 61.1 84.4 1140.4 9.8 220.6 627.1 642.1 126.5 17.7 192.4 1.0 5.5 61.8 21.4 524.1 54.9 967.0 584.2 159.1 38.3 75.0 144.2 105.2 226.4 846.5 15.2 46.4 904.0 221.9 259.7 604.6 116.7 400.5 1619.4 HSPA1L "HSP70-HOM, hum70t" ENSG00000204390 "Heat shock protein family A (Hsp70) member 1 like" P34931 6 31809619-31815283 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "testis: 63.2" "Group enriched" "Detected in many" 22 "Early spermatids: 212.5;Late spermatids: 560.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.1;EFO-21: 1.5;HEK 293: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA043285, HPA052504" Enhanced Approved Nucleoplasm,Vesicles NA NA 53000000 "Cluster 83: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Vesicles Nucleoplasm "HPA043285: AB_10962482, HPA052504: AB_2681854" "unprognostic (1.80e-1)" "unprognostic (8.70e-2)" "unprognostic (2.52e-3)" "unprognostic (6.97e-4)" "unprognostic (2.69e-2)" "unprognostic (1.17e-2)" "unprognostic (4.24e-2)" "unprognostic (4.33e-2)" "unprognostic (1.71e-1)" "prognostic favorable (1.02e-4)" "unprognostic (5.26e-3)" "unprognostic (9.96e-2)" "prognostic favorable (4.63e-4)" "unprognostic (4.48e-2)" "unprognostic (4.30e-1)" "unprognostic (1.02e-1)" "unprognostic (1.53e-3)" 1.2 1.4 0.0 0.0 0.2 0.1 0.9 1.4 0.3 1.5 0.0 1.8 0.1 1.8 0.0 0.6 2.4 0.0 1.4 0.1 0.2 1.5 1.2 1.3 0.0 0.2 0.2 2.2 0.9 0.0 1.7 0.0 0.3 1.1 0.0 0.1 1.0 0.0 3.9 1.0 1.5 0.0 0.2 2.4 1.3 63.2 0.4 0.0 1.5 0.1 0.0 1.6 1.1 0.6 0.1 1.1 0.1 0.4 0.3 0.3 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 1.5 0.0 0.4 0.4 0.1 0.0 0.1 0.3 4.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.4 0.3 0.1 0.2 0.2 0.2 0.3 0.2 0.4 0.6 4.2 0.0 1.1 2.9 3.5 0.9 1.3 0.4 2.2 2.6 1.9 2.0 4.5 0.0 0.9 0.0 8.4 0.6 1.4 1.4 0.0 0.7 212.5 2.0 0.7 2.2 1.8 3.2 0.6 0.2 0.6 1.3 0.0 1.3 0.0 0.9 1.8 1.1 1.3 3.3 0.8 1.4 0.0 4.4 2.5 560.9 5.0 2.1 5.4 2.8 4.1 3.6 1.0 0.5 2.0 0.4 1.4 2.2 1.9 0.9 0.9 0.6 2.2 2.8 0.0 0.8 2.9 17.0 8.7 1.7 0.1 0.4 3.8 0.9 1.5 0.3 HSPA2 ENSG00000126803 "Heat shock protein family A (Hsp70) member 2" P54652 14 64535905-64546173 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 320.2;skeletal muscle: 170.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 342.0;Distal tubular cells: 238.7;Extravillous trophoblasts: 509.9;Spermatocytes: 578.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A549: 75.4;BEWO: 114.4;BJ hTERT+: 99.0;CAPAN-2: 52.9;SCLC-21H: 101.4" "Low region specificity" "Detected in all" "HPA000798, HPA052504" Enhanced Supported Approved Nucleoplasm,Vesicles NA NA 63000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 28: BEWO - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles Nucleoplasm "HPA000798: AB_1079090, HPA052504: AB_2681854" "prognostic favorable (1.78e-4)" "unprognostic (1.72e-1)" "unprognostic (2.73e-1)" "unprognostic (1.08e-2)" "unprognostic (3.78e-2)" "unprognostic (2.90e-2)" "unprognostic (7.11e-2)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.31e-1)" "unprognostic (3.14e-2)" "unprognostic (2.09e-1)" "unprognostic (2.60e-1)" "unprognostic (5.31e-2)" "unprognostic (1.14e-1)" "unprognostic (1.90e-1)" "unprognostic (8.36e-2)" "unprognostic (1.25e-1)" 9.8 6.5 83.9 7.5 161.2 0.7 6.4 148.0 116.3 12.5 84.2 94.1 5.5 51.6 18.6 42.3 17.0 5.3 39.7 88.5 96.0 73.0 4.2 14.2 3.8 170.1 122.9 5.6 8.8 7.8 15.2 61.5 174.9 10.8 9.5 1.2 16.4 4.5 170.4 31.7 29.6 28.7 128.5 20.2 18.5 121.0 125.3 3.0 2.7 60.6 5.0 42.9 16.0 320.2 30.4 75.4 11.4 0.2 8.1 0.7 114.4 42.3 99.0 16.6 27.3 2.9 52.9 7.4 16.8 46.4 3.6 33.6 0.0 2.2 10.1 4.3 5.8 0.1 4.0 0.2 7.9 0.2 10.0 3.7 1.7 2.4 0.1 4.1 1.1 0.5 0.0 6.0 8.4 13.5 0.5 0.4 8.4 11.7 9.1 6.0 0.0 0.1 26.1 4.6 101.4 5.8 1.8 3.7 0.1 3.9 2.9 3.1 1.6 0.3 0.2 3.7 0.2 7.6 0.2 0.2 9.2 0.1 11.4 0.3 0.0 0.0 0.5 0.1 0.0 0.2 0.4 0.2 0.0 0.1 0.1 0.1 0.6 0.2 0.1 0.0 1.0 0.1 83.9 161.2 148.0 116.3 88.5 96.0 170.1 122.9 174.9 128.5 125.3 320.2 74.7 0.0 5.2 18.6 21.1 54.0 31.2 35.1 342.0 1.9 37.5 57.1 39.1 5.7 8.8 132.4 0.0 42.5 30.8 29.2 238.7 8.3 35.7 56.4 63.8 59.6 28.1 0.0 0.5 5.6 509.9 40.7 83.6 54.5 13.3 1.4 32.2 0.8 15.7 0.0 1.1 63.4 24.4 3.1 25.7 27.3 8.7 24.0 30.2 6.5 0.0 14.2 0.0 2.5 157.4 5.5 15.6 7.5 7.1 7.5 8.5 1.5 4.6 2.4 26.3 48.6 66.2 578.6 77.1 175.8 42.3 75.9 29.8 4.5 12.9 11.3 HSPA6 HSP70B' ENSG00000173110 "Heat shock protein family A (Hsp70) member 6" P17066 1 161524540-161526894 "Plasma proteins, Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 242.2;lung: 94.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 335.3;Langerhans cells: 478.8;Macrophages: 213.7;Prostatic glandular cells: 180.1;Smooth muscle cells: 235.6;T-cells: 391.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 8 "cerebral cortex: 242.2" "Immune cell enriched" "Detected in many" 7 "neutrophil: 317.9" "Lineage enriched" "Detected in many" 7 "granulocytes: 317.9" "Cell line enriched" "Detected in some" 7 "Karpas-707: 50.7" "Low region specificity" "Detected in all" "CAB017452, HPA028549, HPA052504" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" Vesicles Nucleoplasm "CAB017452: AB_10618032, HPA028549: AB_10601817, HPA052504: AB_2681854" "unprognostic (3.90e-2)" "unprognostic (2.05e-1)" "unprognostic (5.87e-2)" "unprognostic (2.59e-1)" "unprognostic (2.40e-1)" "unprognostic (6.36e-3)" "prognostic unfavorable (7.26e-4)" "unprognostic (4.61e-2)" "unprognostic (1.29e-1)" "unprognostic (1.93e-1)" "unprognostic (1.68e-1)" "unprognostic (2.25e-1)" "prognostic unfavorable (1.98e-5)" "unprognostic (2.33e-2)" "unprognostic (1.49e-1)" "unprognostic (1.19e-2)" "unprognostic (2.04e-1)" 26.2 15.7 11.3 9.9 16.3 3.6 3.6 22.1 242.2 2.9 24.7 9.3 1.7 1.7 0.7 7.3 3.8 8.7 31.7 12.9 12.4 27.2 33.0 94.4 2.3 15.1 12.4 46.8 5.9 1.1 23.8 20.5 28.7 3.3 1.7 1.8 3.3 5.0 3.8 8.4 5.1 2.3 13.8 63.5 34.5 2.4 15.5 1.3 12.8 3.6 1.7 18.5 10.9 20.1 0.8 1.5 0.0 0.3 0.0 1.1 1.0 0.6 0.5 0.2 0.4 0.5 0.7 0.2 2.2 0.2 0.8 0.4 0.5 0.4 0.3 0.5 0.1 0.3 1.4 0.0 0.0 0.1 3.3 0.2 1.0 0.5 0.0 0.0 0.0 0.2 0.6 50.7 0.0 0.0 0.3 1.3 0.1 0.3 5.4 0.0 0.1 0.7 0.0 0.3 0.1 0.0 0.2 0.9 3.1 0.1 0.4 0.7 0.2 0.1 0.5 0.4 3.6 6.9 0.4 0.0 1.3 1.3 2.3 6.5 35.1 13.4 6.4 44.1 1.0 0.2 0.7 3.4 12.2 0.0 0.0 1.6 317.9 8.3 37.7 0.2 0.0 11.8 11.3 16.3 22.1 242.2 12.9 12.4 15.1 12.4 28.7 13.8 15.5 20.1 14.0 9.6 9.3 0.3 23.8 29.3 335.3 4.4 5.2 42.5 8.7 36.2 11.1 0.0 12.2 5.5 127.2 1.8 12.8 25.3 0.0 0.4 3.2 16.2 16.4 36.7 71.0 24.0 0.0 0.0 11.2 98.8 30.1 26.2 2.5 0.0 3.9 0.3 76.0 10.1 0.0 71.0 4.1 47.8 478.8 1.1 5.6 213.7 103.2 1.0 15.8 36.1 5.2 0.0 0.1 0.3 16.5 0.0 104.1 180.1 0.0 1.5 17.1 36.9 0.0 11.1 235.6 2.9 0.6 16.5 21.7 18.3 391.3 3.6 67.3 92.7 HSPA8 "HSC70, HSC71, HSP73, HSPA10" ENSG00000109971 "Heat shock protein family A (Hsp70) member 8" P11142 11 123057489-123063230 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Stress response, Transcription, Transcription regulation" "Chaperone, Hydrolase, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 2455.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002056, HPA052504" Uncertain Approved Nucleoplasm,Vesicles NA Yes 140000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Vesicles "CAB002056: , HPA052504: AB_2681854" "unprognostic (2.28e-3)" "unprognostic (1.19e-3)" "prognostic favorable (6.14e-6)" "unprognostic (1.75e-1)" "unprognostic (1.84e-2)" "unprognostic (5.70e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (9.65e-3)" "unprognostic (3.82e-1)" "unprognostic (9.64e-2)" "unprognostic (2.93e-1)" "unprognostic (3.22e-1)" "prognostic favorable (3.81e-4)" "unprognostic (2.53e-1)" "unprognostic (1.83e-1)" "unprognostic (2.74e-1)" "unprognostic (7.16e-2)" 539.8 604.9 456.3 542.1 498.1 442.4 448.9 591.6 887.9 326.6 571.4 435.8 506.9 367.3 614.7 554.2 498.5 508.6 892.4 535.1 614.9 850.5 763.2 480.1 685.0 564.8 564.2 421.4 1238.1 593.8 501.9 487.1 620.0 411.2 525.8 531.5 404.1 439.8 1519.0 224.4 453.5 508.4 554.2 520.3 676.7 395.0 559.8 628.6 422.6 1508.5 879.6 866.0 302.4 656.8 1369.6 2077.3 1370.5 1176.5 1259.4 1337.4 1775.6 2730.9 1550.4 3373.2 2004.8 3151.7 1787.3 2318.5 1614.6 1591.9 2337.3 1835.9 4091.6 1027.2 3323.5 1955.4 605.9 2570.4 881.5 1532.0 347.5 2418.0 1757.1 721.8 1594.5 1045.0 320.7 1753.4 1845.6 321.7 2727.8 1147.0 2704.5 1235.5 2507.0 1761.3 2063.2 3463.3 1874.0 2214.4 962.2 1281.3 1665.1 1008.4 1371.8 1023.9 1980.4 2110.5 763.6 1491.1 1837.1 901.9 1767.0 1621.1 1246.1 1404.5 2402.7 740.6 1985.0 1890.9 1791.1 3316.9 1970.0 517.7 592.3 587.8 1245.4 1159.8 1499.6 1009.2 1441.8 1366.1 656.1 752.2 1367.5 1326.5 201.8 1110.7 1255.0 465.5 1761.7 3439.4 456.3 498.1 591.6 887.9 535.1 614.9 564.8 564.2 620.0 554.2 559.8 656.8 795.5 192.3 228.2 72.5 576.3 282.3 2455.6 315.3 507.6 206.7 454.5 380.1 396.3 278.8 352.8 130.6 127.2 926.1 740.3 513.1 528.3 589.0 49.8 404.1 380.1 512.8 519.8 551.7 33.4 628.8 1032.6 609.7 366.0 366.5 434.8 633.8 249.9 223.9 810.9 181.7 45.6 511.1 303.2 359.8 1060.8 58.2 222.4 590.6 528.3 35.6 530.9 307.4 639.5 28.1 50.3 513.8 552.1 270.0 573.6 779.5 823.0 1002.2 465.7 278.1 243.3 416.3 893.1 248.9 419.2 590.6 284.6 1512.1 1123.5 430.3 632.0 1171.5 HSPB9 CT51 ENSG00000260325 "Heat shock protein family B (small) member 9" Q9BQS6 17 42122804-42123352 "Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 17.8" "Group enriched" "Detected in some" 5 "Early spermatids: 375.3;Late spermatids: 1017.0" "Cancer enhanced" "Detected in single" "liver cancer: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.3;HEK 293: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA053091 Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Vesicles, Cytosol" "HPA053091: " "unprognostic (2.36e-1)" "unprognostic (2.63e-1)" "unprognostic (8.35e-2)" "unprognostic (1.99e-2)" "unprognostic (5.67e-2)" "unprognostic (8.37e-2)" "unprognostic (2.30e-2)" "unprognostic (3.42e-6)" "unprognostic (2.31e-1)" "unprognostic (5.13e-2)" "unprognostic (3.82e-1)" "unprognostic (8.62e-2)" "unprognostic (3.36e-3)" "unprognostic (3.68e-4)" "unprognostic (4.78e-2)" "unprognostic (4.01e-1)" "unprognostic (1.24e-1)" 0.4 0.2 1.3 0.4 1.4 0.6 0.2 1.6 1.7 0.2 0.9 0.3 0.3 0.2 0.0 0.1 0.7 0.6 0.2 1.2 1.3 0.5 3.6 0.2 0.4 1.4 1.2 1.3 4.8 0.2 0.5 0.2 1.4 0.5 0.0 0.0 2.9 0.5 1.5 0.4 0.4 0.1 1.2 0.5 0.4 17.8 1.4 0.0 0.2 1.0 0.0 0.2 0.2 1.7 0.2 0.2 0.3 0.9 0.0 0.0 3.3 0.0 0.0 0.0 0.3 1.0 0.1 0.3 0.1 0.0 0.1 0.0 0.4 0.2 0.0 0.3 3.0 0.5 1.2 0.4 0.0 0.3 1.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.4 0.2 0.0 0.4 0.3 1.1 0.1 0.3 0.0 0.1 0.2 1.0 0.0 0.7 1.4 0.3 0.0 1.5 0.2 0.1 0.2 0.1 0.4 0.7 0.0 0.6 0.2 0.6 0.3 0.6 0.1 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.3 0.5 0.0 0.0 1.3 1.4 1.6 1.7 1.2 1.3 1.4 1.2 1.4 1.2 1.4 1.7 0.7 0.0 0.0 0.0 0.0 0.4 0.5 0.1 0.6 0.6 0.6 0.5 0.6 2.8 0.0 0.0 2.1 3.2 0.2 0.4 19.6 0.0 375.3 0.5 0.3 0.6 0.0 0.0 0.1 1.1 0.8 0.7 0.0 0.3 0.0 0.5 1.8 15.3 0.2 3.3 0.1 0.7 0.0 0.8 0.4 1017.0 7.2 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.3 6.8 0.0 0.4 0.6 0.9 0.1 0.4 0.0 0.8 0.3 127.3 4.5 0.1 0.3 0.3 0.2 0.6 0.3 0.2 HSPBP1 FES1 ENSG00000133265 "HSPA (Hsp70) binding protein 1" Q9NZL4 19 55262223-55280381 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Respiratory ciliated cells: 119.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 270.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005865, HPA070398, HPA071444" Supported Approved Vesicles,Centrosome,Cytosol NA NA 19000 "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Vesicles, Centrosome" "CAB005865: AB_304116, HPA070398: , HPA071444: AB_2686396" "unprognostic (3.07e-2)" "unprognostic (6.36e-2)" "unprognostic (5.41e-2)" "unprognostic (8.05e-2)" "unprognostic (9.24e-2)" "unprognostic (1.43e-1)" "unprognostic (3.71e-3)" "unprognostic (1.12e-2)" "unprognostic (5.72e-2)" "unprognostic (1.52e-1)" "unprognostic (6.20e-3)" "unprognostic (7.23e-2)" "unprognostic (4.28e-3)" "unprognostic (2.44e-2)" "unprognostic (2.62e-1)" "unprognostic (9.45e-2)" "unprognostic (2.14e-2)" 24.6 29.0 41.4 14.5 50.8 16.6 25.4 41.4 60.5 29.8 34.1 34.9 15.7 39.3 5.2 42.1 38.4 6.2 46.9 41.9 40.3 38.8 37.9 23.9 12.3 40.3 41.8 34.3 27.4 18.9 26.8 8.3 38.6 29.3 6.7 7.3 25.2 10.4 46.9 33.7 24.0 8.0 39.2 21.0 28.9 32.5 39.6 9.6 27.1 16.9 8.1 33.3 29.7 39.5 86.9 150.0 27.1 38.6 15.3 14.3 78.8 44.3 17.8 45.0 38.3 85.5 57.7 56.1 42.1 24.3 27.0 59.0 33.1 43.9 11.6 48.4 270.8 74.9 48.2 79.7 34.1 72.3 38.1 18.5 39.4 44.6 20.9 19.4 22.5 46.5 61.6 31.1 15.8 80.3 65.4 64.2 95.6 75.2 125.8 63.7 41.7 121.0 30.4 54.8 71.0 108.0 54.2 54.2 46.9 14.4 41.7 56.4 29.8 50.3 55.0 29.4 83.1 48.4 126.9 60.0 57.6 62.6 56.6 2.0 25.7 7.2 39.1 45.4 40.9 53.9 42.2 44.7 52.9 64.3 42.1 41.1 1.7 44.2 39.6 29.3 43.3 25.1 41.4 50.8 41.4 60.5 41.9 40.3 40.3 41.8 38.6 39.2 39.6 39.5 11.8 9.6 11.5 5.5 15.6 26.8 39.7 55.5 29.6 15.9 20.1 20.8 13.2 34.3 35.1 35.0 6.2 48.0 11.6 46.4 72.4 62.5 13.4 69.4 15.2 18.5 22.6 18.1 8.6 46.1 57.0 22.0 25.5 13.4 10.8 20.0 10.4 23.9 39.1 13.5 11.6 31.7 44.7 11.3 13.7 16.0 19.6 11.9 17.8 3.7 28.2 14.9 21.6 6.0 7.3 42.6 44.4 17.7 27.3 29.5 25.5 62.5 119.8 14.8 26.3 24.2 31.9 39.0 28.8 27.9 29.5 37.5 17.1 16.6 58.9 35.2 HTRA3 "Prsp, Tasp" ENSG00000170801 "HtrA serine peptidase 3" P83110 4 8269754-8307098 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 194.9" "Cell type enhanced" "Detected in some" "Fibroblasts: 158.8;Leydig cells: 43.5;Peritubular cells: 42.9;Skeletal myocytes: 99.0;Theca cells: 25.2" "Cancer enhanced" "Detected in all" "pancreatic cancer: 67.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "U-2197: 182.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 10.3" "HPA021187, HPA063810" Approved Approved Vesicles "Secreted in other tissues" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA021187: AB_1851311, HPA063810: AB_2685129" "unprognostic (5.87e-2)" "unprognostic (1.40e-2)" "unprognostic (2.89e-2)" "unprognostic (9.32e-2)" "unprognostic (1.84e-1)" "unprognostic (3.09e-2)" "unprognostic (1.12e-3)" "unprognostic (5.29e-2)" "unprognostic (3.81e-2)" "unprognostic (1.15e-1)" "unprognostic (1.95e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (1.61e-9)" "unprognostic (1.65e-3)" "unprognostic (2.56e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.34e-2)" 68.0 6.0 0.9 8.7 1.3 13.4 50.4 0.9 1.3 35.4 5.0 33.9 8.7 42.4 10.6 15.1 26.2 35.5 194.9 0.9 1.0 6.2 3.2 38.0 1.2 1.0 1.0 93.0 6.8 0.4 15.7 20.4 1.0 26.3 4.8 0.1 22.8 6.7 32.1 28.1 16.9 11.8 1.0 2.9 21.9 4.3 1.7 2.2 26.0 12.9 0.7 62.4 32.6 0.7 0.0 1.0 1.4 0.0 5.8 10.8 0.3 2.4 0.2 2.8 0.6 0.1 0.1 0.0 13.6 6.4 1.4 0.1 1.2 0.0 0.9 0.0 2.3 1.3 13.9 0.0 6.1 0.0 0.6 1.2 0.0 4.2 0.0 1.7 9.8 0.0 0.3 0.0 10.2 0.0 0.2 36.5 6.1 0.0 0.3 0.3 0.0 0.1 0.0 0.0 15.8 0.3 26.4 0.5 0.2 28.8 0.1 1.1 8.1 1.4 4.7 182.1 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 1.3 0.9 1.3 0.9 1.0 1.0 1.0 1.0 1.0 1.7 0.7 12.6 0.0 0.0 0.0 0.0 5.2 0.5 0.0 0.6 0.0 0.5 0.9 16.5 0.0 0.6 0.0 0.0 0.8 0.1 0.0 0.0 0.1 1.2 0.3 8.1 5.3 0.0 0.0 0.0 0.0 4.2 158.8 0.5 0.3 0.0 6.0 3.3 0.0 1.4 0.0 0.0 0.0 0.0 0.0 8.6 1.4 43.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 42.9 0.4 0.4 0.0 0.1 0.0 0.0 0.0 99.0 10.6 0.4 0.7 0.6 5.3 1.4 0.9 25.2 0.0 0.2 HYKK "AGPHD1, LOC123688" ENSG00000188266 "Hydroxylysine kinase" A2RU49 15 78507564-78537372 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 29.4;Late spermatids: 33.7;Proximal enterocytes: 37.0;Proximal tubular cells: 39.4;Skeletal myocytes: 28.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 3.0" "Lineage enriched" "Detected in single" 6 "T-cells: 3.0" "Cell line enhanced" "Detected in many" "HEK 293: 22.2;U-266/84: 24.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040706 Approved Approved Vesicles,Aggresome NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles Aggresome "HPA040706: AB_10795528" "unprognostic (9.26e-2)" "unprognostic (1.98e-4)" "unprognostic (7.84e-2)" "unprognostic (3.16e-2)" "unprognostic (3.64e-1)" "unprognostic (2.72e-2)" "unprognostic (1.14e-1)" "unprognostic (8.00e-3)" "unprognostic (2.73e-1)" "unprognostic (5.16e-2)" "unprognostic (6.24e-3)" "unprognostic (6.37e-2)" "unprognostic (3.44e-3)" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (3.11e-3)" "unprognostic (3.90e-2)" 4.5 4.8 2.8 1.0 3.1 1.3 4.5 2.2 3.2 5.6 1.6 4.6 7.3 3.8 5.9 2.8 4.3 2.4 5.3 2.7 2.2 12.3 5.7 2.1 2.0 2.0 2.0 6.1 6.8 4.8 3.5 0.7 1.8 4.1 3.4 2.6 3.5 4.1 6.2 2.8 7.2 3.6 1.6 1.3 5.1 5.3 2.3 1.9 4.5 5.4 1.7 3.9 3.8 2.9 4.3 6.3 1.0 11.3 2.3 5.3 2.7 1.5 2.7 3.7 4.2 2.2 4.9 3.1 1.4 2.5 6.3 5.2 10.0 3.3 3.5 1.5 22.2 1.7 3.8 5.6 6.0 0.5 1.9 4.8 6.4 1.4 2.7 1.8 2.7 13.8 4.0 8.4 2.2 5.0 4.2 1.0 0.7 9.8 8.3 2.4 12.4 2.7 7.1 5.1 1.3 1.6 2.9 8.6 10.9 1.9 9.5 0.4 1.9 2.4 1.8 4.3 4.4 12.9 24.2 0.2 3.2 0.2 3.4 0.4 0.1 0.2 0.1 0.0 0.1 0.1 1.1 0.1 0.0 0.1 3.0 0.6 0.3 0.1 0.0 0.3 0.5 0.4 2.8 3.1 2.2 3.2 2.7 2.2 2.0 2.0 1.8 1.6 2.3 2.9 4.1 12.8 4.1 4.6 1.4 3.6 7.7 4.5 6.2 2.0 4.5 9.8 6.7 0.0 2.9 7.3 2.1 7.3 1.5 2.8 29.4 2.5 14.0 2.7 3.3 4.1 4.2 1.3 2.8 7.9 4.4 5.4 5.1 1.5 0.0 2.4 6.8 7.1 0.8 0.0 2.7 3.9 2.0 1.0 0.9 33.7 5.3 1.0 7.2 2.8 0.3 7.5 0.0 0.5 1.1 2.9 3.6 3.8 1.7 3.7 37.0 39.4 3.5 1.9 0.0 28.1 4.0 5.4 8.0 4.9 1.6 3.4 1.6 3.9 5.7 4.7 IAPP "AMYLIN, DAP, IAP" ENSG00000121351 "Islet amyloid polypeptide" P10997 12 21354959-21379980 "Predicted intracellular proteins, Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 53 "pancreas: 166.7" "Group enriched" "Detected in some" 5 "Early spermatids: 44.5;Pancreatic endocrine cells: 15.2" "Cancer enriched" "Detected in single" 76 "pancreatic cancer: 21.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-2 OS: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000352, HPA053194" Enhanced Approved Vesicles "Secreted to blood" NA NA 11900 "Cluster 11: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 9: U-2 OS - Unknown function" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "CAB000352: AB_2121635, HPA053194: AB_2682076" "unprognostic (5.52e-3)" "unprognostic (1.00e-1)" "unprognostic (4.16e-1)" "unprognostic (1.74e-1)" "unprognostic (1.91e-1)" 0.5 0.0 0.1 0.0 0.2 1.0 0.0 0.5 0.3 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.1 2.3 0.0 0.2 0.1 0.5 0.0 166.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 3.1 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.1 0.3 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.5 0.3 0.1 0.2 0.1 0.5 0.2 0.0 0.8 0.5 0.0 0.0 1.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 44.5 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 5.9 0.3 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 1.5 0.3 0.3 0.2 0.0 0.4 0.3 0.3 0.1 0.0 0.8 ICA1 "ICA69, ICAp69" ENSG00000003147 "Islet cell autoantigen 1" Q05084 7 8113184-8262687 "Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 594.7;Late spermatids: 867.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "T-reg: 29.9" "Lineage enriched" "Detected in many" 9 "T-cells: 29.9" "Cell line enhanced" "Detected in many" "CAPAN-2: 47.1;MCF7: 42.5;OE19: 48.4;RT4: 49.4;SCLC-21H: 66.1;SH-SY5Y: 105.8;SK-BR-3: 52.1;T-47d: 43.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017646, HPA061452" Approved Supported Vesicles,Cytosol NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 25: Pancreas - Digestion" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Vesicles, Cytosol" "HPA017646: AB_1851382, HPA061452: AB_2684525" "unprognostic (1.39e-1)" "unprognostic (1.37e-1)" "unprognostic (3.74e-1)" "unprognostic (6.83e-3)" "unprognostic (9.49e-2)" "unprognostic (8.57e-3)" "unprognostic (1.37e-2)" "unprognostic (3.54e-1)" "unprognostic (7.61e-2)" "unprognostic (3.42e-1)" "unprognostic (5.84e-2)" "unprognostic (2.62e-1)" "prognostic favorable (4.23e-8)" "unprognostic (1.30e-1)" "unprognostic (1.29e-1)" "unprognostic (2.77e-2)" "unprognostic (4.08e-2)" 15.8 10.4 11.3 5.7 16.2 23.8 21.1 21.5 21.8 16.4 1.2 22.8 13.6 6.8 13.6 9.5 13.7 11.1 44.3 13.4 9.3 16.0 8.8 11.2 13.5 8.0 9.5 1.7 62.7 20.9 19.8 8.2 9.3 22.1 23.5 2.9 37.1 4.9 2.8 12.8 17.8 5.6 5.1 12.4 30.5 24.2 13.3 5.0 14.1 3.3 9.6 13.8 7.4 15.3 0.0 1.5 1.7 0.2 0.2 0.0 4.2 0.0 0.0 0.6 0.2 1.0 47.1 0.3 5.2 0.1 0.9 0.0 0.8 1.9 0.0 0.0 6.8 9.1 0.9 0.0 0.4 9.1 1.8 0.0 3.0 0.0 0.0 0.5 31.5 8.2 26.4 0.0 0.0 42.5 0.4 0.0 9.9 48.4 0.4 0.0 0.0 19.5 19.0 49.4 66.1 105.8 0.0 52.1 0.7 11.6 43.4 14.3 19.8 0.0 0.9 0.2 1.0 14.1 7.5 0.0 0.0 6.9 10.3 1.0 2.4 0.2 0.3 0.8 0.6 0.4 5.4 0.4 2.4 0.7 0.3 0.2 3.4 0.9 0.4 0.6 29.9 1.3 11.3 16.2 21.5 21.8 13.4 9.3 8.0 9.5 9.3 5.1 13.3 15.3 73.4 28.9 24.4 6.5 1.6 20.5 16.2 7.1 9.1 10.4 42.8 28.7 43.2 22.8 20.1 22.0 6.2 2.7 2.1 28.2 43.0 38.4 594.7 34.2 5.8 44.1 77.2 16.4 132.1 74.8 0.8 4.5 56.1 65.4 8.2 11.2 42.1 1.3 23.9 0.0 138.0 80.5 44.7 8.1 9.3 867.0 7.5 9.6 14.2 60.0 6.3 0.8 3.1 49.3 3.9 59.8 53.1 3.0 1.7 53.8 23.8 8.3 17.8 1.7 6.6 1.2 5.6 13.9 9.6 18.4 8.9 2.2 9.5 4.7 41.8 42.7 ICAM1 "BB2, CD54" ENSG00000090339 "Intercellular adhesion molecule 1" P05362 19 10271093-10286615 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 219.3;urinary bladder: 215.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 612.2;Alveolar cells type 2: 561.6;Endothelial cells: 240.8;Langerhans cells: 232.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 158.3;Karpas-707: 459.7;RPMI-8226: 148.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002126, CAB002142, HPA004877" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA 87900000 2200000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Vesicles, Cytosol" "CAB002142: AB_563596, HPA002126: AB_1078470, HPA004877: AB_1846317" "prognostic favorable (7.09e-4)" "unprognostic (1.88e-1)" "unprognostic (1.94e-1)" "unprognostic (2.63e-2)" "unprognostic (3.25e-3)" "unprognostic (3.05e-1)" "unprognostic (1.45e-2)" "unprognostic (3.48e-1)" "unprognostic (3.18e-2)" "unprognostic (1.09e-2)" "unprognostic (1.49e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (1.32e-6)" "unprognostic (2.77e-1)" "unprognostic (2.16e-2)" "unprognostic (2.25e-1)" "unprognostic (3.70e-3)" 87.9 23.6 9.1 44.6 9.6 117.1 32.4 7.9 12.0 11.2 9.9 17.7 16.8 23.9 3.5 11.0 26.2 56.4 39.1 8.8 9.9 43.9 67.1 219.3 38.3 12.3 8.7 13.0 11.1 8.3 9.3 27.8 10.2 22.2 18.1 10.5 18.0 6.3 15.1 17.9 22.6 23.4 10.0 55.9 21.5 5.6 15.4 28.4 30.8 12.8 32.9 215.3 12.5 10.2 46.3 0.5 7.9 0.2 2.0 4.4 9.7 8.6 91.6 21.8 62.0 14.0 49.8 39.6 130.3 3.8 99.3 8.9 1.7 0.4 45.6 123.8 0.1 3.8 1.4 62.0 158.3 1.3 23.9 55.7 4.0 13.7 20.3 2.0 10.7 4.9 15.0 459.7 1.5 3.3 0.5 34.9 3.1 0.5 24.7 1.0 0.2 148.5 36.8 0.3 0.3 1.1 61.2 3.3 94.5 3.7 6.9 2.8 34.3 22.3 1.9 12.3 0.8 137.4 142.7 25.5 35.1 26.3 32.6 5.0 28.3 5.2 5.3 25.8 9.8 3.8 4.0 6.3 24.7 1.5 1.9 3.8 40.8 15.2 17.0 14.1 6.1 20.8 9.1 9.6 7.9 12.0 8.8 9.9 12.3 8.7 10.2 10.0 15.4 10.2 150.3 612.2 561.6 0.3 31.7 85.3 22.2 62.6 28.5 0.0 50.2 24.9 1.1 21.5 133.5 3.7 0.0 1.1 28.9 2.9 0.0 176.8 2.0 14.1 15.5 240.8 2.4 1.3 0.5 98.7 3.3 136.6 13.7 29.8 139.8 0.1 48.2 12.1 86.7 0.0 0.4 0.7 32.6 53.6 232.6 1.3 4.7 168.3 76.5 7.5 101.9 4.6 5.2 0.5 0.2 113.7 0.3 1.5 57.6 27.1 0.3 15.0 83.2 0.4 6.6 38.2 57.6 0.8 1.6 4.3 69.3 1.2 28.8 0.5 1.6 14.1 IDI2 IPPI2 ENSG00000148377 "Isopentenyl-diphosphate delta isomerase 2" Q9BXS1 10 1018910-1025859 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Isoprene biosynthesis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "skeletal muscle: 273.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Glandular and luminal cells: 1.1;Horizontal cells: 1.7;Skeletal myocytes: 3.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041254 Uncertain Vesicles NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" Vesicles "HPA041254: AB_10794270" "unprognostic (6.69e-3)" "unprognostic (4.05e-2)" "unprognostic (1.64e-1)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 2.8 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.1 0.0 0.2 0.1 0.0 1.2 0.0 0.0 273.8 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.1 0.0 11.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.7 0.4 0.3 0.0 0.1 0.2 0.2 0.0 0.6 0.3 0.5 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.4 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.9 0.5 0.4 0.2 0.0 0.0 0.3 0.0 0.1 0.1 0.0 1.1 0.0 0.1 0.0 0.0 0.2 1.7 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 3.2 0.2 0.3 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.2 IDO1 "IDO, INDO" ENSG00000131203 "Indoleamine 2,3-dioxygenase 1" P14902 8 39902275-39928790 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Immunity, Tryptophan catabolism" "Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 58.7;placenta: 110.9" "Cell type enriched" "Detected in many" 11 "monocytes: 2612.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 14 "eosinophil: 465.0" "Lineage enriched" "Detected in many" 18 "granulocytes: 465.0" "Cell line enriched" "Detected in some" 7 "EFO-21: 61.8" "Region enriched" "Detected in many" 12 "basal ganglia: 34.1" "Low region specificity" "Detected in all" "HPA023072, HPA023149, HPA027772, CAB072820" Enhanced Supported Nucleoplasm,Vesicles,Mitochondria,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 3: Monocytes - Immune response regulation" Cytosol "Nucleoplasm, Vesicles, Mitochondria" "CAB072820: , HPA023072: AB_1846220, HPA023149: AB_1846221, HPA027772: AB_1846222" "unprognostic (1.68e-2)" "unprognostic (1.71e-2)" "unprognostic (4.08e-3)" "unprognostic (7.21e-3)" "unprognostic (1.90e-1)" "unprognostic (1.09e-2)" "unprognostic (1.86e-1)" "unprognostic (3.06e-2)" "prognostic favorable (5.27e-4)" "prognostic favorable (3.32e-4)" "unprognostic (3.59e-2)" "unprognostic (2.74e-1)" "prognostic unfavorable (1.12e-7)" "unprognostic (4.18e-2)" "unprognostic (4.42e-2)" "unprognostic (1.16e-1)" "unprognostic (1.97e-2)" 9.8 0.7 0.6 40.5 0.4 0.7 2.0 0.4 0.8 7.2 1.0 5.3 10.3 10.2 1.2 1.3 2.6 6.2 1.8 0.4 0.6 1.7 2.4 25.9 58.7 0.7 0.3 1.2 1.2 0.2 0.1 110.9 0.5 2.0 8.2 1.3 1.9 3.0 8.1 1.3 8.4 2.4 0.4 23.0 5.8 1.1 0.8 31.2 4.0 0.6 31.5 9.1 0.5 0.6 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.9 7.6 4.8 0.3 0.8 0.0 61.8 0.0 3.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.1 0.4 0.1 0.0 0.0 0.2 0.0 0.3 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.1 8.4 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 2.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 9.1 0.2 0.2 0.0 0.3 0.0 32.5 1.3 465.0 0.1 1.4 0.1 0.2 0.1 0.0 26.4 0.3 0.1 0.2 4.9 0.1 0.1 0.3 0.1 1.2 0.6 0.4 0.4 0.8 0.4 0.6 0.7 0.3 0.5 0.4 0.8 0.6 24.9 0.0 0.5 0.7 4.4 0.4 0.2 18.3 0.0 0.0 0.5 0.1 0.3 0.0 76.0 0.0 0.0 0.0 0.3 8.3 0.0 4.4 3.7 70.1 23.0 6.9 0.0 0.0 0.2 8.1 0.0 0.3 0.0 223.3 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 2.0 3.7 28.1 1.8 0.0 13.6 0.0 0.0 2612.3 3.0 0.0 0.0 0.1 0.4 0.0 0.4 2.4 0.5 0.0 0.0 33.3 0.2 0.0 1.2 8.4 0.0 0.1 0.1 0.6 0.0 1.3 0.0 1.3 2.0 IDUA "MPS1, MPSI" ENSG00000127415 Alpha-L-iduronidase P35475 4 986997-1004564 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Leydig cells: 19.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 29.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025901, HPA046979, HPA054254" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 170000 "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "CAB025901: , HPA046979: AB_2679888, HPA054254: AB_2682429" "unprognostic (3.62e-2)" "unprognostic (9.08e-2)" "prognostic unfavorable (3.13e-4)" "unprognostic (7.23e-2)" "unprognostic (1.45e-1)" "unprognostic (2.31e-2)" "unprognostic (1.83e-1)" "unprognostic (1.67e-1)" "unprognostic (1.43e-2)" "unprognostic (1.89e-3)" "unprognostic (2.64e-2)" "unprognostic (4.61e-3)" "prognostic unfavorable (7.87e-5)" "unprognostic (2.24e-1)" "unprognostic (1.55e-1)" "unprognostic (2.46e-2)" "prognostic favorable (8.04e-5)" 13.5 17.6 3.4 2.2 3.4 2.9 16.1 9.2 7.5 17.5 2.9 10.3 3.6 15.4 2.4 9.9 16.3 3.7 11.6 3.8 1.5 15.9 13.6 13.9 3.5 3.2 2.1 17.0 21.0 2.8 17.2 1.7 2.4 18.5 1.8 1.8 16.6 4.5 3.7 8.9 14.3 2.0 1.0 18.9 17.1 5.6 2.9 3.4 17.0 0.7 1.3 12.0 13.9 2.6 1.8 0.4 0.0 1.1 12.7 3.6 5.3 10.7 8.5 1.2 1.7 0.6 6.4 0.8 10.7 5.0 1.0 0.5 0.1 0.3 0.4 6.1 0.6 1.0 0.8 0.1 5.8 0.8 4.6 9.3 3.1 0.6 0.0 3.4 1.0 0.7 0.6 0.0 1.6 0.0 2.2 2.5 0.8 11.9 5.5 2.7 0.0 1.1 3.5 0.9 0.1 3.3 0.3 0.0 5.7 1.3 1.2 2.3 9.3 9.0 1.6 2.6 1.2 29.0 1.4 0.4 7.8 3.3 1.8 0.0 1.5 0.0 1.4 1.2 1.8 0.1 1.1 0.9 1.8 0.2 1.3 0.7 0.0 1.5 1.7 1.1 0.6 0.5 3.4 3.4 9.2 7.5 3.8 1.5 3.2 2.1 2.4 1.0 2.9 2.6 8.7 6.4 5.0 4.9 5.2 3.6 11.5 1.1 8.6 2.0 8.5 9.1 2.6 1.5 1.5 7.3 4.2 0.4 4.3 5.0 0.0 1.6 0.9 4.1 9.0 4.9 10.7 1.3 4.4 2.4 1.7 13.4 16.8 6.0 2.5 8.2 6.1 2.6 6.5 0.0 2.9 4.2 0.0 5.0 3.6 0.9 19.6 7.3 5.4 1.0 1.6 1.1 4.1 5.5 3.3 1.4 6.9 10.5 15.7 7.7 6.9 1.4 1.4 2.1 0.0 5.5 4.4 3.7 1.6 4.7 1.8 0.4 5.6 4.7 4.3 7.9 IFI30 "GILT, IFI-30, IP-30, IP30, MGC32056" ENSG00000216490 "IFI30 lysosomal thiol reductase" P13284 19 18173162-18178117 "Predicted intracellular proteins, Predicted membrane proteins" Immunity Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 572.7;lymphoid tissue: 708.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 155.9;Kupffer cells: 205.4;Langerhans cells: 139.3;Macrophages: 426.2;monocytes: 144.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 9509.8;eosinophil: 3890.4;intermediate monocyte: 14243.6;myeloid DC: 5699.9;non-classical monocyte: 9865.9" "Group enriched" "Detected in all" 8 "dendritic cells: 5699.9;granulocytes: 3890.4;monocytes: 14243.6" "Cell line enhanced" "Detected in many" "Daudi: 655.7;RPMI-8226: 717.7;SK-BR-3: 457.4;U-266/84: 794.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026650 Enhanced Supported Vesicles,Cytosol "Intracellular and membrane" NA NA 110000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Cytosol" "HPA026650: AB_10602237" "unprognostic (4.66e-2)" "unprognostic (1.25e-4)" "unprognostic (2.35e-3)" "unprognostic (7.40e-2)" "unprognostic (1.76e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-3)" "unprognostic (2.40e-1)" "unprognostic (4.01e-2)" "unprognostic (9.19e-3)" "unprognostic (3.04e-1)" "unprognostic (1.19e-1)" "unprognostic (7.29e-11)" "unprognostic (3.50e-1)" "unprognostic (1.62e-2)" "unprognostic (3.39e-2)" "unprognostic (9.59e-3)" 132.4 121.0 18.4 708.3 20.8 283.8 58.6 20.3 104.5 40.8 48.7 129.0 197.3 22.2 26.9 38.7 57.3 109.6 31.2 18.0 23.3 80.3 148.2 572.7 370.7 32.0 24.9 14.8 61.3 75.0 27.9 128.8 40.5 31.6 148.0 2.6 66.3 22.0 12.6 55.0 153.6 165.0 26.8 385.3 112.2 16.0 69.4 91.9 54.2 9.0 221.0 215.7 19.6 49.8 115.5 59.2 0.4 37.9 11.2 19.9 102.6 11.8 17.2 34.6 91.8 132.3 193.1 655.7 96.6 39.7 175.2 85.1 69.9 30.1 3.7 182.5 55.2 8.1 98.1 188.9 111.8 20.1 46.9 70.4 60.4 59.8 19.7 4.4 2.0 23.8 96.8 394.8 16.6 217.3 9.9 2.5 21.2 380.6 68.7 65.8 4.5 717.7 101.1 3.7 5.3 8.0 200.5 457.4 11.3 7.4 31.6 8.8 4.2 55.2 34.2 120.7 12.0 14.6 794.7 368.5 154.1 133.5 8.5 106.9 9509.8 3890.4 40.8 14243.6 38.8 952.6 28.5 31.1 5699.9 708.1 19.7 24.3 2102.8 70.2 9865.9 173.2 41.5 11082.7 18.4 20.8 20.3 104.5 18.0 23.3 32.0 24.9 40.5 26.8 69.4 49.8 6.4 9.6 38.8 0.0 54.2 3.6 2.5 2.1 2.2 0.4 8.6 13.2 1.1 4.3 18.3 12.9 0.0 5.6 4.0 8.3 1.9 1.8 0.3 2.5 1.7 8.4 0.0 4.6 0.1 1.1 14.8 8.1 6.6 4.1 13.9 0.2 3.6 1.3 155.9 0.0 0.1 14.9 2.0 205.4 139.3 0.2 0.3 426.2 5.4 1.0 144.1 0.7 5.2 0.0 0.1 1.2 3.4 0.0 47.7 4.6 5.9 5.4 8.9 0.7 0.0 2.6 1.8 0.2 0.7 3.7 3.3 12.0 9.6 1.5 9.6 1.2 IFIT2 "cig42, G10P2, GARG-39, IFI-54, IFI54, ISG-54K" ENSG00000119922 "Interferon induced protein with tetratricopeptide repeats 2" P09913 10 89283694-89309271 "Predicted intracellular proteins" "Antiviral defense, Apoptosis, Immunity, Innate immunity" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 48.4" "Cell type enhanced" "Detected in many" "Adipocytes: 53.5;Glandular and luminal cells: 67.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 420.2" "Lineage enriched" "Detected in all" 5 "granulocytes: 420.2" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 141.0;BJ hTERT+ SV40 Large T+ RasG12V: 113.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003408 Approved Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA003408: AB_1079100" "unprognostic (1.77e-1)" "unprognostic (2.10e-1)" "unprognostic (2.42e-2)" "unprognostic (2.25e-3)" "unprognostic (1.75e-2)" "unprognostic (9.28e-2)" "unprognostic (6.71e-3)" "unprognostic (2.22e-1)" "unprognostic (5.40e-1)" "unprognostic (1.36e-1)" "unprognostic (7.03e-3)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.99e-4)" "unprognostic (2.92e-2)" "unprognostic (1.03e-2)" "unprognostic (5.33e-3)" "unprognostic (6.46e-2)" 7.7 6.7 12.6 13.1 17.3 48.4 5.4 14.7 16.2 6.1 8.2 5.4 6.7 5.0 6.2 2.8 9.3 13.6 7.5 11.7 14.1 10.2 21.8 21.0 7.9 19.5 16.6 9.2 3.1 10.0 2.5 16.4 18.9 4.1 4.5 1.7 8.8 6.5 2.3 3.7 5.7 6.5 30.1 27.5 3.6 2.2 15.9 12.6 3.4 6.8 5.7 6.3 2.9 20.8 29.3 1.1 0.3 14.5 13.0 14.4 5.2 10.7 32.4 141.0 113.0 0.1 20.0 3.2 5.9 7.8 20.6 28.9 0.6 1.5 15.4 11.6 0.1 5.3 14.3 0.0 22.2 0.7 2.3 8.2 0.7 10.7 1.6 8.6 0.7 2.8 0.1 0.5 2.2 0.1 3.4 6.6 3.5 0.0 6.1 2.1 3.7 0.8 4.8 5.6 0.1 0.2 3.8 0.6 24.7 1.8 0.7 1.6 0.9 1.5 0.3 3.9 1.1 1.4 5.1 0.5 2.3 2.4 2.9 97.6 32.6 107.8 9.5 75.9 5.1 19.2 8.0 6.5 10.6 17.7 7.6 6.8 420.2 8.9 92.3 12.7 3.9 17.6 12.6 17.3 14.7 16.2 11.7 14.1 19.5 16.6 18.9 30.1 15.9 20.8 53.5 41.7 6.7 1.6 12.3 1.5 5.3 6.6 1.2 1.3 5.6 9.5 7.4 11.5 9.4 12.9 0.0 2.9 27.6 23.5 9.8 35.0 0.2 34.9 9.1 34.9 3.5 0.8 1.0 4.2 1.6 10.9 2.0 67.0 5.1 3.8 16.4 6.1 26.0 25.2 2.1 5.9 4.1 25.5 3.3 0.2 8.1 29.5 7.2 4.7 20.9 13.3 12.3 2.0 20.3 6.3 11.5 11.7 2.4 19.1 18.9 30.8 4.7 0.9 0.0 8.3 14.3 0.2 0.2 3.2 0.6 1.4 13.1 6.2 2.1 5.8 IFITM5 "BRIL, DSPA1, fragilis4, Hrmp1" ENSG00000206013 "Interferon induced transmembrane protein 5" A6NNB3 11 298200-299526 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Mineral balance" "Developmental protein" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 4.9;pancreas: 7.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 8 "cerebral cortex: 4.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA039258 Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Vesicles, Cytosol" "HPA039258: AB_10673608" "unprognostic (9.84e-2)" "unprognostic (2.15e-1)" "unprognostic (1.38e-1)" "unprognostic (5.80e-2)" "unprognostic (7.46e-2)" "unprognostic (4.20e-2)" "unprognostic (4.42e-2)" "unprognostic (8.31e-2)" "unprognostic (7.99e-3)" "unprognostic (1.94e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (4.90e-2)" 0.1 0.0 0.0 0.1 0.0 0.7 0.2 0.0 4.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.2 0.4 0.1 0.1 0.1 0.0 7.3 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.1 0.1 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IGDCC3 "HsT18880, PUNC" ENSG00000174498 "Immunoglobulin superfamily DCC subclass member 3" Q8IVU1 15 65327127-65378002 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.3;parathyroid gland: 5.1;placenta: 6.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 33.3;Cytotrophoblasts: 104.8;Early spermatids: 37.6;Late spermatids: 98.6;Syncytiotrophoblasts: 41.3" "Group enriched" "Detected in many" 5 "glioma: 2.2;testis cancer: 5.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 105.8;CACO-2: 27.4;Hep G2: 87.8;SuSa: 41.9" "Low region specificity" "Detected in many" HPA015713 Uncertain Nucleoplasm,Vesicles NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Vesicles" "HPA015713: " "unprognostic (7.11e-2)" "unprognostic (1.99e-1)" "unprognostic (4.24e-2)" "unprognostic (7.25e-3)" "unprognostic (6.67e-2)" "unprognostic (7.35e-3)" "unprognostic (3.93e-2)" "unprognostic (1.53e-1)" "unprognostic (1.82e-2)" "unprognostic (4.56e-1)" "unprognostic (1.61e-1)" "unprognostic (1.78e-1)" "unprognostic (5.77e-5)" "unprognostic (4.15e-1)" "unprognostic (1.26e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-2)" 0.0 0.2 2.3 0.0 2.0 0.0 0.8 4.3 3.2 1.0 0.0 0.4 0.0 0.7 0.1 0.0 0.6 0.1 0.1 2.6 1.9 0.2 0.0 0.0 0.0 2.4 2.7 0.8 0.0 5.1 1.9 6.0 2.4 0.1 0.0 1.0 0.0 0.1 0.1 0.1 0.1 0.2 1.6 0.0 0.2 2.8 3.0 1.4 0.9 0.0 0.0 0.1 0.4 1.9 0.0 0.0 105.8 4.7 0.0 0.0 1.3 0.0 0.0 0.0 0.0 27.4 0.2 0.0 0.3 0.0 0.0 0.0 7.2 0.0 0.0 0.0 1.0 0.0 0.2 87.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 16.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 2.2 1.5 0.1 0.1 0.0 41.9 3.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.0 4.3 3.2 2.6 1.9 2.4 2.7 2.4 1.6 3.0 1.9 0.1 0.0 0.0 15.3 0.0 0.0 0.2 0.0 0.0 4.1 2.2 1.0 0.6 0.0 0.0 1.8 33.3 104.8 0.0 0.4 0.0 0.0 37.6 0.4 4.8 1.0 0.0 0.0 2.8 0.0 4.3 3.0 0.0 0.6 0.0 0.1 0.0 0.0 7.2 0.0 7.0 0.0 0.0 0.0 0.0 98.6 0.6 0.1 0.0 1.0 0.0 3.7 0.0 16.1 8.9 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 3.1 0.0 0.7 0.4 1.3 11.0 0.0 0.0 41.3 0.1 0.1 0.2 0.0 IGF2 "C11orf43, FLJ44734, IGF-II" ENSG00000167244 "Insulin like growth factor 2" P01344 11 2129112-2141238 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Carbohydrate metabolism, Glucose metabolism, Osteogenesis" "Growth factor, Hormone, Mitogen" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "placenta: 2749.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1104.3;Extravillous trophoblasts: 3196.3;Leydig cells: 3007.5;Peritubular cells: 643.9;Syncytiotrophoblasts: 1612.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 86.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 862.0;Hep G2: 600.5;LHCN-M2: 333.7;RH-30: 408.5;SH-SY5Y: 495.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007556, HPA007993" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 609000000 1200000000 "Cluster 28: Placenta - Pregnancy" "Cluster 39: CACO-2 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "HPA007556: AB_2667860, HPA007993: AB_1851474" "unprognostic (1.54e-1)" "unprognostic (1.65e-2)" "unprognostic (1.31e-1)" "unprognostic (7.08e-2)" "unprognostic (2.30e-3)" "unprognostic (2.59e-1)" "prognostic favorable (7.12e-4)" "unprognostic (7.92e-2)" "unprognostic (2.59e-2)" "unprognostic (1.68e-2)" "unprognostic (3.69e-2)" "unprognostic (1.85e-1)" "unprognostic (1.79e-3)" "unprognostic (2.00e-2)" "unprognostic (8.98e-2)" "unprognostic (8.93e-3)" "unprognostic (5.78e-2)" 99.7 58.4 5.5 9.2 32.6 0.9 41.8 12.6 86.0 75.5 236.8 22.3 4.7 75.2 52.7 18.8 128.4 34.8 91.7 6.5 7.1 31.8 305.9 9.8 3.4 20.2 6.6 117.8 37.5 5.2 25.4 2749.2 10.1 14.5 4.8 0.5 11.6 15.2 82.1 8.4 10.9 14.7 13.0 14.4 11.9 23.7 10.9 3.4 12.4 114.0 4.7 24.2 23.6 9.0 0.0 2.8 0.3 0.6 0.2 0.3 1.8 112.8 1.3 3.6 0.4 862.0 0.4 0.1 8.4 0.0 2.1 0.1 0.9 7.0 7.9 0.1 0.5 0.2 0.2 600.5 143.4 0.7 0.0 174.7 0.5 0.7 0.2 0.1 1.4 0.0 0.3 0.0 333.7 2.2 0.1 0.8 1.2 0.2 1.5 0.1 408.5 0.9 0.0 0.9 32.7 495.6 0.7 0.1 0.0 83.0 4.2 0.0 0.4 0.2 20.1 0.2 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 32.6 12.6 86.0 6.5 7.1 20.2 6.6 10.1 13.0 10.9 9.0 40.6 3.2 3.1 0.0 2.6 5.4 0.5 0.5 0.6 0.4 0.0 0.0 6.5 8.6 0.9 3.7 0.0 1104.3 0.0 0.0 0.0 0.0 13.1 0.0 0.0 498.4 0.0 16.0 0.0 0.0 3196.3 334.2 0.0 0.0 0.0 0.0 171.4 494.9 218.2 0.0 0.0 0.0 0.0 11.6 5.5 91.1 3007.5 3.4 3.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 643.9 0.0 1.1 0.0 0.0 0.9 0.5 65.7 33.5 37.5 3.8 6.3 1.5 4.1 1612.9 1.8 0.0 0.0 0.4 IGF2R "CD222, CI-M6PR, CI-MPR, CIMPR, M6P-R, MPR1, MPR300, MPRI" ENSG00000197081 "Insulin like growth factor 2 receptor" P11717 6 159969082-160113507 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 69.5" "Cell type enhanced" "Detected in many" "NK-cells: 264.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.4" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009661, HPA011332" Supported Enhanced "Golgi apparatus,Vesicles" NA NA 190000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 65: Plasmacytoid DCs - Unknown function" "Golgi apparatus, Vesicles" "CAB009661: AB_2122795, HPA011332: AB_1846276" "prognostic unfavorable (3.01e-4)" "prognostic unfavorable (2.92e-5)" "unprognostic (5.83e-2)" "unprognostic (1.72e-1)" "unprognostic (4.15e-1)" "unprognostic (3.25e-1)" "unprognostic (7.32e-3)" "unprognostic (2.32e-1)" "unprognostic (1.62e-1)" "unprognostic (1.07e-2)" "unprognostic (2.37e-1)" "unprognostic (1.45e-1)" "unprognostic (5.74e-3)" "unprognostic (1.16e-1)" "unprognostic (1.46e-1)" "unprognostic (1.85e-1)" "prognostic unfavorable (6.08e-4)" 20.3 21.9 1.8 11.4 3.7 13.3 16.0 3.9 4.3 15.2 11.7 17.4 7.4 19.3 4.8 16.7 13.9 10.7 21.8 3.2 4.2 14.8 23.9 22.2 8.2 4.3 3.6 17.0 16.6 14.3 9.5 15.3 3.8 11.0 11.6 3.2 18.4 6.7 69.5 16.5 14.7 16.0 3.2 23.2 15.5 7.7 4.8 15.9 14.5 27.2 7.8 15.3 16.5 5.9 20.8 18.1 32.6 44.6 108.4 76.4 36.9 30.1 80.4 30.3 52.8 28.3 37.2 7.3 30.9 38.4 101.7 25.4 27.0 140.0 52.0 47.7 19.4 3.6 30.0 32.1 49.2 20.7 31.2 52.7 45.4 57.6 144.8 65.4 19.2 36.0 42.2 48.2 46.4 10.1 8.8 13.4 13.1 19.3 23.2 23.2 20.6 46.1 29.9 20.8 11.3 25.4 45.0 34.5 44.8 41.4 15.7 49.4 25.3 27.0 27.9 57.3 60.4 16.7 40.2 9.1 49.0 23.7 38.9 0.5 1.0 0.8 1.1 0.3 0.4 0.2 0.5 0.4 0.2 0.2 0.5 0.7 4.4 0.7 0.4 1.3 0.2 0.3 1.8 3.7 3.9 4.3 3.2 4.2 4.3 3.6 3.8 3.2 4.8 5.9 44.7 48.1 47.3 34.6 16.7 22.2 10.0 16.0 17.1 13.0 20.2 14.7 33.6 24.3 22.1 16.5 20.9 7.5 107.0 46.2 0.0 29.3 7.5 25.8 38.7 29.6 22.3 9.5 33.0 19.4 12.3 29.9 16.8 39.7 3.8 41.7 28.9 63.4 22.2 15.2 34.2 18.4 12.2 59.4 12.8 5.2 47.5 37.6 12.4 31.9 65.9 11.7 264.7 30.7 40.0 40.8 17.2 38.4 35.9 17.1 23.2 23.6 12.2 15.1 65.7 63.7 32.6 10.9 10.4 28.9 19.7 9.3 38.8 38.8 20.9 16.7 IGFBP3 "BP-53, IBP3" ENSG00000146674 "Insulin like growth factor binding protein 3" P17936 7 45912245-45921874 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Growth factor binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 1864.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 457.7;Basal respiratory cells: 777.7;Extravillous trophoblasts: 2064.1;Fibroblasts: 463.4;Urothelial cells: 809.9" "Cancer enhanced" "Detected in all" "renal cancer: 377.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 54.5" "Lineage enriched" "Detected in many" 5 "dendritic cells: 54.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 8578.6;U-2197: 3469.4;U-87 MG: 1774.2" "Low region specificity" "Detected in all" CAB010360 Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 3250000000 3600000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Cytosol" "CAB010360: AB_2233528" "unprognostic (4.46e-3)" "unprognostic (4.84e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.30e-1)" "unprognostic (1.15e-1)" "unprognostic (6.54e-2)" "prognostic unfavorable (1.64e-4)" "unprognostic (8.14e-3)" "unprognostic (3.31e-2)" "unprognostic (2.03e-1)" "unprognostic (9.67e-3)" "unprognostic (2.80e-1)" "prognostic unfavorable (5.07e-7)" "unprognostic (2.36e-2)" "unprognostic (4.14e-2)" "unprognostic (2.37e-3)" "unprognostic (2.63e-1)" 350.6 16.2 15.6 28.5 20.2 1.2 278.2 12.2 24.1 291.8 18.9 96.7 67.8 547.3 43.1 28.2 130.9 44.6 284.6 16.5 22.5 65.9 721.3 37.5 68.3 20.7 13.7 233.1 14.4 28.0 98.1 1864.4 21.0 87.4 58.4 11.9 46.2 81.1 57.9 176.5 77.9 198.1 12.8 191.0 81.7 10.8 16.5 18.2 40.8 73.3 67.4 369.7 165.3 15.9 199.6 59.5 113.1 1.0 83.9 34.7 0.9 850.6 153.8 71.9 38.8 0.2 157.4 0.2 263.2 8578.6 35.6 466.5 1.5 3.4 29.2 0.6 0.1 0.3 20.8 0.2 21.9 0.4 1.6 285.7 12.8 15.1 53.8 112.3 0.7 0.0 0.1 3.2 26.8 1.2 1.3 1.4 7.8 1.8 10.9 0.8 0.4 81.4 53.2 423.6 13.6 32.7 293.9 11.4 15.3 250.6 1.5 0.7 0.5 815.4 1.7 3469.4 49.3 11.6 0.7 1.1 1774.2 0.3 282.1 0.0 0.0 0.0 10.1 0.0 8.0 0.0 10.9 10.7 0.0 0.0 4.9 8.1 0.1 0.0 0.0 54.5 0.8 4.5 15.6 20.2 12.2 24.1 16.5 22.5 20.7 13.7 21.0 12.8 16.5 15.9 260.4 3.2 3.9 0.7 1.9 457.7 148.9 777.7 8.0 2.8 12.6 30.4 12.6 8.6 409.7 228.1 0.0 94.1 10.0 0.7 11.7 145.6 1.3 32.3 220.1 168.0 273.7 5.3 2.5 2.0 2064.1 463.4 1.5 31.3 1.3 12.2 182.0 2.6 80.9 0.0 5.6 8.4 57.0 7.2 21.9 3.5 288.3 3.5 16.0 1.9 7.2 0.6 0.0 0.5 0.2 19.0 2.5 6.8 1.0 212.1 0.8 1.0 136.0 0.5 0.0 12.6 124.6 0.8 1.4 9.3 244.6 154.2 9.3 3.6 2.0 809.9 IGFBP5 ENSG00000115461 "Insulin like growth factor binding protein 5" P24593 2 216672105-216695549 "Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1492.5;ovary: 1323.4" "Cell type enhanced" "Detected in many" "Fibroblasts: 1104.1;Ionocytes: 980.6;Leydig cells: 1828.2;Peritubular cells: 981.7;Sertoli cells: 1275.3;Skeletal myocytes: 2750.9;Smooth muscle cells: 1376.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 831.3;BJ hTERT+: 2192.6;T-47d: 531.7;U-138 MG: 710.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059827, HPA070407" Supported Approved "Nuclear bodies,Golgi apparatus,Vesicles" "Secreted to blood" NA NA 110000000 380000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus, Vesicles" "Nuclear bodies" "HPA059827: AB_2732640, HPA070407: " "unprognostic (7.69e-2)" "unprognostic (2.56e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (4.58e-2)" "unprognostic (3.47e-1)" "unprognostic (2.04e-1)" "unprognostic (1.76e-1)" "unprognostic (1.32e-1)" "unprognostic (9.58e-2)" "unprognostic (1.12e-1)" "unprognostic (2.41e-2)" "unprognostic (4.04e-2)" "unprognostic (9.62e-3)" "unprognostic (1.55e-1)" "unprognostic (3.28e-2)" "unprognostic (1.91e-3)" 375.1 221.8 35.6 178.2 35.1 0.7 354.6 21.9 30.9 1492.5 46.9 232.3 35.0 837.7 121.3 166.4 953.0 129.3 155.0 50.4 41.8 479.1 34.2 78.2 71.3 36.3 37.9 1323.4 30.7 30.7 272.8 290.7 31.5 241.4 66.2 105.4 111.0 121.8 470.9 129.0 139.3 621.2 28.1 38.7 323.5 28.8 43.8 95.0 326.2 292.9 45.9 259.2 382.9 62.4 0.0 0.0 210.6 0.9 237.1 7.5 0.8 831.3 2192.6 108.8 10.4 0.0 1.0 0.1 3.3 2.3 0.0 0.1 26.2 0.0 5.6 0.1 8.2 218.1 4.4 0.2 103.1 0.1 1.8 33.1 0.0 14.7 0.1 24.8 0.1 0.2 0.7 0.1 0.5 70.9 0.9 1.2 2.3 0.0 3.4 0.3 0.8 1.2 70.3 249.1 14.5 8.5 14.6 100.4 0.0 12.8 531.7 0.1 80.3 710.2 42.2 109.3 41.0 0.7 0.1 0.1 1.4 0.1 23.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.6 35.1 21.9 30.9 50.4 41.8 36.3 37.9 31.5 28.1 43.8 62.4 237.3 3.2 4.4 40.1 20.6 102.5 13.5 211.0 25.0 8.7 73.9 199.9 92.0 5.7 251.6 112.2 6.2 3.9 1.7 0.0 5.9 10.3 8.4 140.2 250.7 120.8 0.0 0.0 6.0 0.0 4.5 1104.1 30.5 128.5 2.5 11.4 49.6 1.4 8.7 3.3 13.7 0.0 980.6 0.6 189.7 39.9 1828.2 18.4 101.4 29.0 0.6 674.4 0.0 5.5 0.4 2.2 0.0 981.7 5.5 17.0 0.0 1.1 120.9 18.7 1275.3 2750.9 1376.0 2.2 3.0 17.7 67.9 5.6 18.4 124.7 0.1 16.8 IGFBPL1 bA113O24.1 ENSG00000137142 "Insulin like growth factor binding protein like 1" Q8WX77 9 38406528-38424454 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "thyroid gland: 16.5" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 1.8;Excitatory neurons: 2.5;Hofbauer cells: 1.9;Inhibitory neurons: 1.6;Oligodendrocyte precursor cells: 2.5;Spermatogonia: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 360.4;NTERA-2: 104.2;RH-30: 97.5;SCLC-21H: 334.3;SH-SY5Y: 332.6;SuSa: 241.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA051354 Uncertain Uncertain Nucleoplasm,Vesicles "Secreted to blood" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "HPA051354: " "unprognostic (5.63e-2)" "unprognostic (3.33e-1)" "unprognostic (5.22e-2)" "unprognostic (2.42e-1)" "unprognostic (2.56e-2)" "unprognostic (1.92e-1)" "unprognostic (1.30e-1)" "unprognostic (5.66e-2)" "unprognostic (2.26e-1)" "unprognostic (3.05e-1)" "unprognostic (2.00e-2)" "unprognostic (2.35e-1)" "unprognostic (2.73e-1)" "unprognostic (3.94e-1)" "unprognostic (3.92e-2)" "unprognostic (1.59e-2)" "unprognostic (6.67e-2)" 0.8 1.5 2.4 0.5 4.2 0.5 0.1 3.4 2.8 0.2 1.4 0.5 0.9 0.7 0.1 0.3 0.3 0.6 1.3 2.6 2.0 0.2 0.3 0.8 0.2 1.5 2.3 0.1 0.9 0.0 1.1 0.6 1.7 0.4 0.3 0.3 0.1 1.6 0.2 0.2 0.6 1.1 1.0 0.1 1.6 2.1 2.8 2.9 16.5 0.0 0.1 0.5 0.1 1.8 0.0 8.6 360.4 0.4 0.0 0.0 0.2 2.4 0.0 0.5 0.3 0.1 0.2 0.1 1.3 0.3 0.0 0.1 44.0 0.0 0.5 0.0 2.7 0.1 1.2 0.2 0.0 1.7 1.2 0.4 0.0 0.0 0.0 0.2 0.0 1.6 0.2 0.2 2.5 0.1 0.3 0.2 104.2 0.5 0.7 0.1 97.5 0.9 0.0 0.2 334.3 332.6 6.4 0.5 0.0 241.3 2.3 2.3 0.4 0.1 7.7 0.3 0.0 0.1 0.0 0.1 0.0 0.1 0.7 0.5 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.4 0.2 0.1 0.2 0.1 0.0 2.4 4.2 3.4 2.8 2.6 2.0 1.5 2.3 1.7 1.0 2.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.3 0.6 0.1 0.0 1.8 0.0 2.5 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.4 0.0 0.0 0.1 0.0 0.0 0.2 0.0 IGIP "C5orf53, LOC492311" ENSG00000182700 "IgA inducing protein" A6NJ69 5 140125937-140129392 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 55.4" "Cell type enhanced" "Detected in many" "Horizontal cells: 28.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 13.7;ASC TERT1: 13.1" "Low region specificity" "Detected in all" "HPA041877, HPA048615" Uncertain Approved Vesicles "Secreted to blood" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" Vesicles "HPA041877: AB_2677721, HPA048615: AB_2680462" "unprognostic (1.15e-1)" "unprognostic (1.12e-1)" "unprognostic (5.85e-2)" "unprognostic (2.00e-2)" "unprognostic (2.46e-1)" "unprognostic (1.16e-2)" "unprognostic (1.28e-1)" "unprognostic (1.10e-1)" "unprognostic (2.38e-1)" "unprognostic (5.05e-2)" "prognostic favorable (3.94e-4)" "unprognostic (1.94e-1)" "prognostic favorable (6.25e-6)" "unprognostic (2.93e-3)" "unprognostic (1.70e-1)" "unprognostic (5.98e-2)" "unprognostic (7.77e-2)" 8.3 8.9 43.6 2.9 41.0 0.1 7.7 38.9 55.4 12.7 29.7 14.1 3.7 9.2 9.0 6.3 8.9 3.7 11.8 38.3 40.9 9.3 10.0 9.4 4.5 41.5 43.8 9.9 8.4 13.7 18.6 4.2 43.9 12.0 3.8 19.5 8.0 8.1 10.4 9.0 8.3 4.6 45.7 7.8 9.2 4.0 45.1 4.2 11.9 9.2 3.9 10.7 11.6 40.8 2.0 0.6 0.9 2.8 13.7 13.1 1.3 5.1 5.0 1.1 1.5 2.0 1.6 3.8 5.3 6.9 0.6 2.1 1.1 3.1 2.3 3.4 1.9 0.8 3.0 1.5 3.2 1.0 1.3 4.5 7.7 2.2 4.2 8.6 1.4 2.8 0.6 1.5 4.4 1.8 1.2 2.6 0.2 1.6 1.5 1.2 2.4 1.7 6.6 1.8 1.0 1.5 2.8 1.8 3.1 1.0 1.4 3.0 8.8 3.5 0.3 1.2 2.8 3.6 2.5 1.3 3.7 2.6 2.6 0.0 0.0 0.2 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.2 0.0 43.6 41.0 38.9 55.4 38.3 40.9 41.5 43.8 43.9 45.7 45.1 40.8 6.5 12.8 5.1 14.0 2.3 2.0 2.1 3.2 0.0 21.3 4.5 3.7 14.4 8.6 5.4 3.7 14.6 2.5 1.4 5.5 0.0 3.3 1.9 2.4 3.5 5.4 9.0 0.0 22.2 1.8 1.5 4.4 3.6 2.2 8.2 3.0 7.9 5.9 1.0 28.6 19.8 4.2 0.0 2.2 1.3 1.3 6.5 2.2 7.2 14.0 3.9 5.9 3.1 9.5 17.6 2.8 4.4 17.0 1.3 3.7 7.8 4.2 6.1 8.8 0.0 11.2 5.5 2.4 1.3 1.7 4.0 1.8 1.9 2.8 4.0 2.2 IGSF10 "CMF608, FLJ25972" ENSG00000152580 "Immunoglobulin superfamily member 10" Q6WRI0 3 151425384-151458709 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Osteogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 17.7" "Cell type enhanced" "Detected in many" "Early spermatids: 170.5;Horizontal cells: 60.6;Late spermatids: 34.1;Microglial cells: 61.8;Syncytiotrophoblasts: 30.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HeLa: 44.1;HL-60: 23.3;REH: 17.2;RPMI-8226: 55.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "HPA012655, HPA012921" Uncertain Approved Vesicles "Secreted - unknown location" NA NA 540000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA012655: , HPA012921: AB_1851526" "unprognostic (1.78e-3)" "unprognostic (2.48e-2)" "unprognostic (1.71e-1)" "unprognostic (3.47e-7)" "unprognostic (1.68e-1)" "unprognostic (2.12e-1)" "unprognostic (9.82e-2)" "unprognostic (8.84e-4)" "unprognostic (9.38e-3)" "unprognostic (1.96e-1)" "unprognostic (5.70e-2)" "unprognostic (2.04e-1)" "unprognostic (7.52e-4)" "unprognostic (6.01e-2)" "unprognostic (8.93e-2)" "unprognostic (4.59e-3)" "unprognostic (7.57e-4)" 3.9 4.0 1.4 0.9 0.7 0.6 6.1 0.3 1.0 0.5 3.2 1.3 0.5 1.4 1.6 2.9 4.3 9.7 4.3 2.8 1.1 0.2 0.3 8.6 1.4 0.1 1.0 17.7 0.7 1.3 1.7 0.7 0.3 0.1 1.3 0.2 5.2 0.2 0.1 1.9 1.2 1.5 0.0 0.9 0.7 0.9 3.6 1.3 1.5 0.5 2.5 2.2 0.3 0.3 0.0 0.1 0.3 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.1 0.0 0.4 0.0 0.0 0.3 0.3 7.5 44.1 0.0 1.6 23.3 0.1 0.4 0.0 0.0 0.0 0.6 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 17.2 0.1 55.1 0.1 0.1 1.0 0.0 5.9 0.0 0.0 0.2 0.0 0.2 0.0 0.1 1.1 0.0 0.0 2.4 0.0 0.0 0.2 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.4 0.7 0.3 1.0 2.8 1.1 0.1 1.0 0.3 0.0 3.6 0.3 2.0 0.0 0.5 1.0 0.6 2.4 1.2 0.5 2.8 15.8 0.6 0.9 1.6 2.8 6.3 1.8 4.2 21.7 2.7 0.2 0.0 0.1 170.5 11.4 4.0 0.9 6.0 3.4 2.4 1.3 2.9 20.4 0.5 0.5 0.0 0.0 0.0 0.1 1.3 60.6 2.8 0.7 4.1 0.8 3.2 34.1 6.8 2.9 3.6 61.8 1.1 25.6 0.0 0.5 0.7 0.4 0.1 1.2 0.3 0.7 0.0 0.3 12.5 2.4 0.0 0.5 2.2 10.7 7.9 0.8 2.4 30.9 0.6 2.5 0.1 0.2 IGSF8 "CD316, CD81P3, EWI2, PGRL" ENSG00000162729 "Immunoglobulin superfamily member 8" Q969P0 1 160091340-160098943 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 155.3" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 219.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 177.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011917, HPA075970" Approved Supported Vesicles NA NA 280000 "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "HPA011917: AB_1851536, HPA075970: " "unprognostic (4.08e-1)" "prognostic unfavorable (7.32e-4)" "unprognostic (1.30e-2)" "unprognostic (9.31e-2)" "unprognostic (1.46e-1)" "unprognostic (1.20e-1)" "unprognostic (1.71e-1)" "unprognostic (1.01e-3)" "unprognostic (1.63e-2)" "unprognostic (1.65e-1)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (2.31e-1)" "unprognostic (2.60e-2)" "unprognostic (2.35e-1)" "unprognostic (3.74e-3)" "unprognostic (1.75e-3)" 21.9 19.1 97.9 14.0 119.0 3.7 26.7 91.7 130.7 25.7 39.9 31.7 26.5 19.8 22.7 22.3 28.2 12.3 29.0 106.0 82.4 35.5 53.9 23.6 16.8 109.3 97.8 37.5 31.8 15.8 30.7 11.2 99.9 26.4 10.4 14.3 30.1 18.2 12.4 50.3 28.5 7.0 98.6 24.2 27.5 33.4 94.7 13.6 28.6 7.1 8.9 20.3 25.0 155.3 26.8 15.7 20.1 51.3 11.6 7.3 42.9 12.9 16.8 26.9 25.0 17.9 17.9 39.0 47.1 18.8 23.4 50.3 8.2 18.9 3.8 47.3 15.0 5.1 17.3 31.2 19.2 13.5 41.7 9.0 37.7 17.5 5.6 19.0 5.6 42.0 7.0 21.8 6.3 25.4 33.8 31.3 42.4 55.6 24.8 19.1 10.3 28.7 24.7 27.4 8.5 36.6 14.8 47.4 177.6 17.5 33.7 17.3 5.8 11.8 25.4 21.5 10.6 59.6 71.2 17.7 41.6 5.3 31.6 0.1 5.2 2.4 22.0 7.2 19.5 19.6 18.0 25.6 5.8 22.7 23.4 25.7 1.4 9.2 4.7 9.9 26.9 11.3 97.9 119.0 91.7 130.7 106.0 82.4 109.3 97.8 99.9 98.6 94.7 155.3 12.2 9.6 3.3 18.3 21.1 43.7 30.2 43.1 26.2 55.6 28.0 29.2 3.3 17.2 16.7 38.6 10.4 32.8 15.1 36.1 5.9 34.2 3.8 12.0 7.2 7.8 19.9 7.4 65.3 12.4 219.7 22.4 6.6 26.4 10.2 12.2 13.2 28.8 14.9 65.6 43.8 24.7 44.7 4.3 16.2 1.1 16.8 8.5 42.7 9.4 51.5 75.7 10.3 9.0 107.2 20.6 39.5 15.8 20.0 22.0 47.6 15.8 6.0 11.8 6.6 39.8 15.3 4.0 6.6 21.0 62.4 69.4 19.5 13.6 32.6 26.0 IL13RA1 "CD213a1, IL-13Ra, NR4" ENSG00000131724 "Interleukin 13 receptor subunit alpha 1" P78552 X 118727133-118794535 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 10.9;eosinophil: 12.2;myeloid DC: 17.2;neutrophil: 29.2" "Group enriched" "Detected in many" 7 "dendritic cells: 17.2;granulocytes: 29.2;monocytes: 10.9" "Cell line enhanced" "Detected in many" "HDLM-2: 181.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001587 Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 17000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" Vesicles Nucleoplasm "HPA001587: AB_1079133" "unprognostic (5.14e-3)" "unprognostic (4.72e-2)" "unprognostic (7.12e-2)" "unprognostic (7.75e-2)" "unprognostic (8.81e-3)" "unprognostic (3.82e-2)" "unprognostic (1.11e-1)" "unprognostic (1.89e-1)" "unprognostic (1.51e-1)" "unprognostic (2.44e-1)" "unprognostic (1.90e-1)" "unprognostic (8.21e-2)" "prognostic unfavorable (1.19e-8)" "unprognostic (1.88e-2)" "unprognostic (2.37e-2)" "unprognostic (2.82e-2)" "unprognostic (5.08e-2)" 51.9 34.3 15.9 40.3 16.2 7.1 41.5 18.1 17.3 27.1 20.4 52.1 48.5 31.9 26.2 53.5 35.8 39.3 20.2 14.6 22.3 33.7 120.3 48.9 25.4 26.0 20.3 37.5 22.3 22.2 15.4 32.8 24.6 22.5 61.6 25.6 34.7 27.1 31.4 20.6 60.8 40.6 22.2 29.9 35.8 16.6 19.6 16.0 29.8 55.9 34.5 31.6 27.4 24.6 31.6 37.2 17.4 48.0 39.0 113.5 33.1 63.3 86.2 29.2 37.6 21.8 55.0 0.1 111.4 86.6 84.8 29.1 19.0 26.6 32.3 181.0 16.5 5.1 30.9 55.8 23.4 0.6 13.0 104.1 23.5 40.0 48.8 87.9 61.8 0.0 16.6 3.3 41.9 44.8 0.1 8.5 16.1 57.8 38.6 0.1 43.3 0.2 43.6 32.9 6.5 6.0 102.3 35.5 24.7 22.8 22.8 28.9 79.3 56.7 26.7 99.7 50.5 0.7 16.8 0.3 125.6 16.1 24.6 0.2 10.9 12.2 0.0 2.7 0.1 2.9 0.0 0.0 17.2 2.5 0.0 0.0 29.2 0.1 1.1 2.9 0.1 2.9 15.9 16.2 18.1 17.3 14.6 22.3 26.0 20.3 24.6 22.2 19.6 24.6 36.0 70.5 48.5 1.0 20.2 17.2 37.1 17.2 18.2 2.1 32.4 26.3 11.5 37.1 46.0 29.5 16.7 8.1 2.8 61.9 9.8 36.1 38.1 25.8 34.0 58.8 93.2 4.8 0.3 98.3 31.9 38.7 38.7 27.3 0.0 13.6 78.9 149.0 41.2 0.0 2.0 138.4 16.2 124.8 140.6 7.3 24.2 120.4 21.4 73.1 199.7 43.7 2.1 0.0 6.9 87.9 27.0 18.8 1.3 42.3 70.8 25.2 49.7 11.2 32.9 14.4 26.2 7.5 28.9 37.2 12.1 9.4 2.7 7.1 29.5 30.8 IL13RA2 "CD213a2, CT19, IL-13R, IL13BP" ENSG00000123496 "Interleukin 13 receptor subunit alpha 2" Q14627 X 115003975-115019977 "Cancer-related genes, CD markers, Predicted membrane proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 12.0;testis: 30.0" "Cell type enriched" "Detected in some" 5 "Early spermatids: 322.4" "Cancer enhanced" "Detected in many" "glioma: 17.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "PC-3: 133.0;U-2197: 425.6;U-251 MG: 297.4;U-87 MG: 167.9" "Region enhanced" "Detected in many" "olfactory bulb: 7.0" "Low region specificity" "Detected in some" "HPA045831, HPA067363" Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 18: U-2197 - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions" "Nucleoplasm, Vesicles" "HPA045831: , HPA067363: " "unprognostic (1.97e-1)" "unprognostic (2.83e-1)" "unprognostic (6.62e-4)" "unprognostic (7.39e-2)" "unprognostic (8.45e-2)" "unprognostic (1.80e-1)" "prognostic favorable (3.55e-4)" "unprognostic (3.54e-1)" "unprognostic (2.85e-1)" "unprognostic (1.92e-2)" "unprognostic (2.20e-3)" "unprognostic (2.19e-2)" "unprognostic (1.53e-5)" "unprognostic (1.58e-1)" "unprognostic (1.63e-1)" "unprognostic (9.70e-3)" "unprognostic (1.20e-1)" 0.8 4.8 1.3 4.0 1.9 0.0 0.4 0.1 1.1 1.1 1.6 0.4 0.3 0.8 4.4 0.6 0.1 0.8 0.7 1.5 10.6 3.6 10.0 1.4 0.1 3.1 3.7 0.1 0.1 0.5 12.0 0.4 1.8 4.1 0.7 0.0 0.9 3.5 0.0 0.2 0.3 0.3 0.7 0.2 0.1 30.0 6.1 2.1 1.2 0.1 0.1 4.4 0.2 0.8 0.4 0.0 4.6 0.1 0.7 3.6 0.0 29.2 28.0 0.1 0.1 0.0 0.0 0.0 0.5 14.6 46.6 0.1 0.0 5.2 0.0 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.1 4.8 0.8 4.6 26.9 0.4 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 133.0 0.0 0.0 0.0 2.4 0.2 0.0 6.8 2.1 0.3 0.4 0.0 0.1 0.4 0.0 14.7 0.4 425.6 297.4 0.0 0.2 0.1 167.9 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.9 0.1 1.1 1.5 10.6 3.1 3.7 1.8 0.7 6.1 0.8 0.3 0.0 0.0 0.0 0.1 0.1 4.7 0.3 0.0 0.0 0.0 0.0 0.2 1.5 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 322.4 0.4 0.3 1.3 4.2 0.0 0.4 0.0 0.0 10.3 0.0 0.4 0.0 0.0 46.4 0.4 0.0 0.0 0.6 0.0 0.0 2.8 0.3 58.6 2.8 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 8.5 0.0 4.9 0.1 10.9 0.0 0.0 2.9 0.0 0.0 0.0 3.4 63.1 4.0 0.0 0.0 0.0 0.1 0.0 0.0 2.3 IL17RB "CRL4, EVI27, IL17BR, IL17RH1" ENSG00000056736 "Interleukin 17 receptor B" Q9NRM6 3 53846568-53865794 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.9;kidney: 59.8;liver: 33.3" "Cell type enhanced" "Detected in many" "Astrocytes: 48.3;Enteroendocrine cells: 29.2;Oligodendrocyte precursor cells: 37.7;Proximal tubular cells: 78.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 20.2;Hep G2: 59.5;OE19: 46.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005482 Enhanced Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" "HPA005482: AB_1234567" "unprognostic (1.85e-3)" "unprognostic (4.22e-3)" "unprognostic (1.60e-3)" "unprognostic (2.86e-2)" "unprognostic (1.42e-2)" "unprognostic (6.20e-3)" "unprognostic (1.62e-2)" "unprognostic (6.09e-3)" "unprognostic (1.30e-1)" "unprognostic (5.41e-2)" "unprognostic (4.75e-2)" "unprognostic (4.27e-2)" "prognostic favorable (6.61e-4)" "unprognostic (8.10e-2)" "unprognostic (6.97e-2)" "unprognostic (5.29e-1)" "unprognostic (7.15e-3)" 0.9 2.0 20.2 2.3 21.4 0.5 5.7 22.7 28.9 18.1 16.6 6.8 5.8 5.1 0.7 1.7 3.3 2.4 2.7 19.4 20.2 59.8 33.3 3.8 2.5 18.7 19.9 1.5 7.8 1.1 4.2 0.9 19.0 2.4 6.9 4.8 4.9 0.6 1.3 2.2 5.9 0.8 18.9 1.2 3.6 2.5 23.2 0.3 2.9 0.2 0.7 0.8 1.3 23.6 1.5 3.1 4.5 3.4 0.1 0.0 7.1 3.1 0.1 0.1 0.0 20.2 1.4 4.6 1.0 1.0 1.7 0.8 12.2 0.0 0.0 1.6 3.5 6.0 6.1 59.5 0.0 5.6 3.2 0.0 0.0 0.0 0.0 3.8 0.0 1.6 4.9 2.1 0.1 4.2 0.9 2.3 12.1 46.2 2.6 1.7 1.9 5.3 1.4 5.3 6.4 3.7 10.1 2.4 1.9 3.3 9.2 2.0 2.5 3.0 3.3 2.6 3.9 4.7 5.6 2.9 2.7 3.3 1.7 1.3 0.2 0.0 0.2 0.2 0.1 0.1 0.6 0.2 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.3 0.9 0.1 20.2 21.4 22.7 28.9 19.4 20.2 18.7 19.9 19.0 18.9 23.2 23.6 0.2 0.0 4.1 48.3 0.2 0.3 2.0 0.0 0.0 0.1 8.2 4.4 4.1 17.2 1.3 0.0 0.0 1.4 0.3 4.3 9.8 4.8 1.0 0.5 1.0 0.2 29.2 0.0 0.5 1.6 1.0 0.6 4.6 1.7 2.5 0.4 0.4 13.1 0.1 0.0 2.5 8.7 2.0 0.0 1.1 0.7 1.2 1.2 0.0 1.9 0.0 4.4 0.0 37.7 4.3 1.8 3.0 0.4 0.0 4.4 2.9 78.0 0.0 0.1 0.0 0.3 0.5 0.4 1.0 0.0 0.1 0.4 0.9 0.0 10.2 0.6 IL1R1 "CD121A, D2S1473, IL1R, IL1RA" ENSG00000115594 "Interleukin 1 receptor type 1" P14778 2 102064544-102179874 "Cancer-related genes, CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 127.1;Endometrial stromal cells: 280.2;Glandular and luminal cells: 315.4;Hepatic stellate cells: 146.7;Langerhans cells: 188.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 624.9;ASC TERT1: 276.8;HHSteC: 196.3;HSkMC: 770.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001237, HPA005823, CAB007779, HPA029560" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1400000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Vesicles" "Plasma membrane, Cytosol" "CAB007779: AB_562073, HPA001237: , HPA005823: AB_2667445, HPA029560: AB_2673094" "unprognostic (6.16e-3)" "unprognostic (3.55e-2)" "unprognostic (3.33e-1)" "unprognostic (1.22e-1)" "unprognostic (4.26e-2)" "unprognostic (7.10e-2)" "unprognostic (2.01e-1)" "unprognostic (3.36e-2)" "unprognostic (1.44e-1)" "unprognostic (3.16e-1)" "unprognostic (4.26e-2)" "unprognostic (7.77e-2)" "prognostic unfavorable (6.92e-6)" "unprognostic (2.48e-2)" "unprognostic (6.95e-2)" "unprognostic (4.83e-2)" "unprognostic (7.73e-2)" 137.3 68.0 7.1 69.5 8.3 18.0 77.5 7.5 11.0 161.1 16.2 39.3 20.7 33.5 105.2 32.1 52.0 92.0 58.3 7.6 9.0 45.7 75.5 115.5 17.1 16.2 8.4 31.1 43.3 126.7 13.1 120.8 8.9 66.7 30.5 8.5 34.2 47.4 18.6 40.1 40.3 49.9 10.0 41.0 43.9 20.6 14.9 21.7 52.5 16.0 19.7 87.4 40.2 7.7 2.0 12.8 0.3 10.8 624.9 276.8 4.4 27.4 123.8 19.2 28.7 5.7 3.4 0.0 19.8 55.0 33.9 5.5 0.2 2.2 16.1 55.5 0.1 0.7 2.9 31.3 196.3 0.1 0.3 770.6 2.3 21.7 5.2 8.4 8.7 0.0 3.5 1.1 28.1 5.6 0.0 1.2 0.7 5.6 0.9 0.3 2.0 0.4 18.3 13.4 0.1 0.3 12.5 7.7 0.0 3.6 11.1 0.8 0.3 54.7 3.6 92.1 2.2 0.1 0.0 0.1 21.3 0.6 3.6 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.6 0.0 7.1 8.3 7.5 11.0 7.6 9.0 16.2 8.4 8.9 10.0 14.9 7.7 99.3 25.6 73.2 1.3 1.8 31.1 46.8 8.2 5.2 0.1 19.4 13.7 5.2 28.6 68.6 5.5 0.0 6.1 2.5 0.7 3.9 31.7 7.0 127.1 280.2 103.6 1.2 14.3 0.5 21.8 82.8 79.1 2.0 315.4 1.3 0.3 146.7 47.1 5.4 0.0 3.0 0.5 10.2 12.0 188.2 12.6 28.0 26.0 19.6 23.4 7.0 9.0 0.0 0.5 0.5 12.0 0.3 1.5 1.8 65.9 0.0 8.3 28.6 1.0 6.6 37.7 34.3 1.3 1.2 4.5 38.6 23.9 8.5 4.0 0.8 23.6 IL1RAP "C3orf13, IL-1RAcP, IL1R3" ENSG00000196083 "Interleukin 1 receptor accessory protein" Q9NPH3 3 190514051-190659750 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 225.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 109.2;Hepatocytes: 295.8;Oligodendrocyte precursor cells: 298.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "eosinophil: 23.8;neutrophil: 95.0" "Lineage enriched" "Detected in many" 15 "granulocytes: 95.0" "Cell line enriched" "Detected in many" 4 "SK-MEL-30: 247.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035293 Uncertain Approved Vesicles,Cytosol "Secreted to blood" NA NA 350000000 "Cluster 1: Neutrophils - Mixed function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 2: Hepatocytes - Metabolism" "Vesicles, Cytosol" "HPA035293: AB_10671511" "unprognostic (6.48e-2)" "unprognostic (1.02e-1)" "unprognostic (3.04e-2)" "unprognostic (1.04e-2)" "unprognostic (1.37e-1)" "unprognostic (8.84e-3)" "unprognostic (2.35e-2)" "unprognostic (6.60e-2)" "unprognostic (2.62e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.72e-1)" "prognostic unfavorable (2.16e-7)" "unprognostic (4.02e-3)" "unprognostic (9.06e-2)" "unprognostic (5.72e-2)" "prognostic unfavorable (6.29e-4)" 6.2 2.9 4.0 11.4 1.1 20.3 4.3 0.0 8.7 4.4 0.5 2.2 1.8 4.0 2.6 13.1 5.4 12.1 3.9 4.6 3.1 3.3 225.8 8.2 2.7 2.4 3.7 3.0 3.9 1.5 1.2 37.0 3.3 3.9 2.2 2.4 5.2 3.4 1.3 11.9 2.2 6.4 1.5 5.4 4.5 1.3 5.5 4.6 4.0 2.1 4.8 9.4 5.5 3.3 13.3 3.0 5.5 0.8 9.5 7.7 10.0 5.8 11.9 13.4 13.2 5.8 29.3 2.2 59.2 16.4 31.1 34.1 3.0 57.6 18.7 2.5 3.6 2.9 5.3 14.5 19.6 20.2 9.5 10.3 23.1 19.7 59.2 27.8 6.0 5.9 0.4 0.2 6.4 6.5 1.7 9.4 8.5 6.0 6.0 9.5 8.2 4.8 5.3 14.8 1.0 0.0 26.3 15.0 247.1 5.2 9.6 14.6 7.9 10.3 10.4 32.1 26.6 5.0 0.2 0.5 17.2 18.0 60.9 11.7 3.8 23.8 1.8 4.3 3.3 2.1 2.1 2.3 3.8 2.1 2.0 1.3 95.0 0.3 6.3 0.6 2.1 1.4 4.0 1.1 0.0 8.7 4.6 3.1 2.4 3.7 3.3 1.5 5.5 3.3 3.5 0.0 14.7 6.5 6.8 44.7 16.5 45.8 68.9 6.5 2.5 4.7 5.5 40.0 22.8 3.7 8.4 8.5 3.6 1.8 0.0 7.7 4.4 8.6 3.8 8.0 5.4 4.4 44.3 7.5 109.2 7.3 7.1 12.3 7.6 0.7 7.5 295.8 7.8 0.0 63.3 1.4 4.1 33.7 17.7 0.6 4.4 28.8 8.8 53.4 5.0 1.0 6.2 298.6 1.5 19.7 0.8 2.6 5.3 11.5 0.7 1.1 8.7 0.6 0.0 18.0 5.1 0.1 0.6 30.9 37.2 24.2 5.2 1.4 1.1 14.3 IL20RB "DIRS1, FNDC6, IL-20R2, MGC34923" ENSG00000174564 "Interleukin 20 receptor subunit beta" Q6UXL0 3 136946230-137011085 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 110.7;skin 1: 163.3;vagina: 66.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 36.8;Basal respiratory cells: 115.8;Basal squamous epithelial cells: 60.9;Club cells: 43.0;Early spermatids: 57.0;Late spermatids: 28.8;Squamous epithelial cells: 56.5;Suprabasal keratinocytes: 38.1" "Group enriched" "Detected in many" 5 "cervical cancer: 54.5;head and neck cancer: 50.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 86.0;HBEC3-KT: 140.0;HHSteC: 91.8;hTCEpi: 555.6;hTERT-HME1: 102.6" "Not detected" "Not detected" HPA063914 Approved Vesicles,Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles Cytosol "HPA063914: AB_2732709" "unprognostic (1.35e-2)" "unprognostic (1.05e-1)" "unprognostic (7.43e-4)" "unprognostic (2.48e-4)" "unprognostic (2.74e-1)" "unprognostic (3.31e-1)" "unprognostic (7.43e-4)" "unprognostic (4.08e-3)" "unprognostic (7.64e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (3.57e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (2.55e-1)" "unprognostic (3.55e-2)" "unprognostic (1.33e-2)" "unprognostic (5.57e-2)" 2.3 0.2 0.1 0.0 0.2 0.0 10.3 0.1 0.6 24.3 0.1 0.6 0.0 0.2 0.0 110.7 0.4 0.0 0.6 0.1 0.1 0.2 5.4 0.5 0.0 0.2 0.1 0.2 0.2 0.0 0.3 0.4 0.2 2.2 0.5 0.0 13.6 0.2 1.0 163.3 0.4 0.0 0.1 0.3 0.5 3.7 0.2 2.0 0.5 0.9 9.5 1.3 66.2 0.2 27.2 0.0 0.1 0.4 15.4 64.9 2.6 0.6 1.8 0.3 1.2 2.7 3.4 0.2 14.9 9.7 1.0 86.0 0.0 140.0 0.7 0.4 0.0 0.3 19.5 0.0 91.8 0.2 0.2 11.5 555.6 4.5 102.6 0.7 0.1 0.1 0.3 0.1 0.0 0.0 0.6 0.0 0.4 2.4 0.0 0.0 0.7 0.2 0.1 0.0 0.0 0.0 54.6 0.0 2.8 4.7 0.5 0.9 0.0 0.2 1.8 0.5 0.5 0.1 0.2 0.2 8.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.6 0.1 0.1 0.2 0.1 0.2 0.1 0.2 0.2 0.7 0.0 0.0 0.7 0.0 36.8 1.7 115.8 60.9 0.0 0.3 0.5 0.4 0.0 43.0 0.0 0.0 1.7 0.8 0.8 0.0 0.9 57.0 0.7 0.4 0.9 0.0 0.0 1.0 0.2 1.4 3.9 0.0 0.8 0.0 0.2 0.0 2.2 0.4 0.0 1.2 0.7 10.2 0.3 6.6 28.8 0.3 0.6 3.6 1.0 1.7 0.0 1.0 1.0 0.2 1.0 0.1 0.7 0.4 1.3 0.2 0.3 5.5 0.0 0.0 0.6 3.6 1.7 1.9 56.5 38.1 1.6 0.6 0.2 0.5 5.3 IL27RA "CRL1, IL-27R, TCCR, WSX-1, WSX1, zcytor1" ENSG00000104998 "Interleukin 27 receptor subunit alpha" Q6UWB1 19 14031762-14053218 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 16.5" "Cell type enhanced" "Detected in many" "B-cells: 49.1;dendritic cells: 56.6;Kupffer cells: 41.1;Langerhans cells: 44.2;NK-cells: 69.0;T-cells: 63.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA073441 Approved Vesicles NA NA 4900000 "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA073441: " "prognostic favorable (1.74e-6)" "unprognostic (1.99e-1)" "unprognostic (1.55e-1)" "unprognostic (6.09e-2)" "unprognostic (2.03e-3)" "unprognostic (2.28e-1)" "unprognostic (2.05e-2)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (1.40e-3)" "unprognostic (9.92e-2)" "unprognostic (3.35e-2)" "prognostic unfavorable (2.58e-10)" "unprognostic (5.45e-3)" "unprognostic (3.91e-2)" "unprognostic (1.76e-1)" "unprognostic (1.87e-3)" 7.8 1.7 2.4 8.7 2.3 2.7 6.5 2.2 2.7 2.7 2.2 3.1 2.3 2.4 0.7 2.6 3.3 2.3 7.7 2.8 2.9 6.1 1.5 8.0 12.6 2.5 2.5 1.0 2.8 5.6 0.8 1.3 2.7 3.6 2.1 0.2 3.0 1.2 2.0 2.2 8.1 1.9 2.5 14.7 2.8 2.0 3.1 11.1 4.0 2.4 16.5 3.9 2.8 2.4 7.7 3.3 3.2 4.4 0.2 1.6 1.3 3.5 7.3 6.3 9.0 1.6 6.1 0.1 3.6 3.1 2.9 1.4 5.1 2.1 4.8 14.8 3.5 18.6 0.7 2.7 0.5 9.0 0.2 1.6 0.8 3.0 0.6 5.1 2.5 4.6 13.1 13.5 0.3 10.7 6.8 19.5 4.2 4.5 2.2 5.8 1.9 7.1 3.9 1.8 2.8 1.5 4.5 0.3 5.2 1.7 5.6 5.4 4.0 0.6 7.7 6.4 3.8 13.9 7.2 6.7 0.6 18.2 4.2 7.9 22.5 0.6 24.3 18.4 21.4 15.6 24.0 20.2 20.7 12.8 26.1 20.6 1.6 22.9 9.5 7.6 23.1 21.4 2.4 2.3 2.2 2.7 2.8 2.9 2.5 2.5 2.7 2.5 3.1 2.4 30.4 0.0 10.0 0.0 49.1 1.9 13.3 8.5 3.4 0.3 14.0 11.9 5.4 5.7 5.7 3.7 0.0 0.6 56.6 0.7 0.0 10.7 0.4 1.9 1.2 22.8 2.4 7.2 2.4 2.7 1.4 4.0 3.6 1.5 17.7 1.4 22.9 0.7 21.4 1.7 2.1 0.9 4.1 41.1 44.2 0.5 3.4 32.8 5.4 1.0 22.8 0.3 69.0 1.0 0.6 3.8 0.8 3.4 26.0 12.4 0.0 0.9 2.0 0.0 0.0 1.9 2.2 0.1 11.5 2.6 1.3 0.1 63.5 0.4 2.4 3.5 IL2RG "CD132, CIDX, IMD4, SCIDX1" ENSG00000147168 "Interleukin 2 receptor subunit gamma" P31785 X 71107404-71112108 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 118.0;lymphoid tissue: 346.4" "Cell type enhanced" "Detected in many" "B-cells: 186.1;dendritic cells: 199.0;Distal enterocytes: 202.0;NK-cells: 310.0;Paneth cells: 133.2;Plasma cells: 221.2;T-cells: 289.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 6 "Karpas-707: 2316.2" "HPA046641, HPA049691" Enhanced Approved Vesicles NA NA 13000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" Vesicles "HPA046641: AB_2679733, HPA049691: AB_2680851" "unprognostic (2.97e-3)" "unprognostic (4.24e-2)" "unprognostic (1.23e-1)" "prognostic favorable (1.73e-4)" "unprognostic (8.25e-2)" "unprognostic (1.93e-3)" "unprognostic (1.37e-1)" "unprognostic (1.53e-1)" "unprognostic (1.91e-3)" "unprognostic (1.23e-2)" "unprognostic (4.36e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (2.28e-7)" "unprognostic (1.73e-1)" "unprognostic (4.69e-2)" "unprognostic (4.89e-2)" "unprognostic (9.54e-2)" 12.8 6.2 2.7 132.2 2.4 87.3 14.1 2.5 6.3 10.2 4.0 98.9 50.4 7.5 7.5 15.1 6.8 28.2 4.6 2.3 2.8 7.1 20.6 51.7 235.6 3.6 2.7 4.9 4.1 1.9 1.5 16.9 4.2 7.8 118.0 0.5 19.0 5.9 2.6 15.4 82.8 12.3 3.1 119.4 41.4 2.2 3.0 346.4 5.8 6.3 306.9 46.4 5.5 3.8 1.2 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.2 0.0 4.7 9.1 187.3 13.5 0.0 0.7 1.7 0.4 0.0 0.0 160.3 0.2 23.6 0.3 0.3 0.2 99.3 4.0 0.0 0.0 0.0 0.1 0.1 0.0 220.5 43.3 2316.2 0.0 0.0 356.4 193.7 0.4 0.9 0.1 79.5 0.8 20.0 0.0 0.7 0.2 0.3 2.3 0.1 0.5 0.0 0.0 3.5 0.4 0.0 1.0 0.0 0.5 132.1 242.2 119.6 2.1 397.4 0.9 540.5 102.2 169.7 1204.7 239.5 1179.9 604.7 1086.3 1250.7 243.5 603.0 742.0 943.1 773.0 1190.3 177.0 368.9 1422.2 1494.0 2.7 2.4 2.5 6.3 2.3 2.8 3.6 2.7 4.2 3.1 3.0 3.8 3.3 3.2 11.2 0.0 186.1 8.2 8.1 13.1 1.2 0.0 1.5 1.7 0.9 4.3 4.2 0.0 0.0 0.5 199.0 202.0 0.0 1.2 0.1 0.8 0.7 5.8 77.7 27.1 0.0 2.3 0.3 4.2 13.7 0.7 39.3 0.4 6.1 2.1 31.1 0.0 0.0 24.5 4.1 25.2 116.7 0.0 0.0 45.4 42.7 1.0 91.1 0.1 310.0 0.0 0.1 28.0 133.2 0.4 221.2 4.3 88.8 1.1 2.3 0.4 0.0 1.3 2.6 0.0 0.1 1.8 6.8 0.3 289.5 0.0 18.6 8.9 IL31RA "CRL, CRL3, GLM-R, Glmr, IL-31RA" ENSG00000164509 "Interleukin 31 receptor A" Q8NI17 5 55851357-55922854 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.6;lymphoid tissue: 2.1;testis: 1.8" "Cell type enhanced" "Detected in some" "Early spermatids: 2.2;Late spermatids: 1.2;Spermatocytes: 2.5;Syncytiotrophoblasts: 1.1" "Cancer enhanced" "Detected in some" "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 26.3;HBEC3-KT: 10.3;HHSteC: 9.5;hTERT-HME1: 11.5;U-2 OS: 16.8;U-87 MG: 20.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.2" "HPA051532, HPA068114" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles Nucleoplasm "HPA051532: , HPA068114: AB_2732779" "unprognostic (1.14e-1)" "unprognostic (5.65e-2)" "unprognostic (1.97e-1)" "unprognostic (5.13e-2)" "unprognostic (2.70e-2)" "unprognostic (2.95e-3)" "unprognostic (7.34e-2)" "unprognostic (3.54e-1)" "unprognostic (5.38e-2)" "unprognostic (2.95e-3)" "unprognostic (7.75e-5)" "unprognostic (5.55e-2)" "unprognostic (2.65e-6)" "unprognostic (7.73e-2)" "unprognostic (7.68e-2)" "unprognostic (4.02e-1)" "unprognostic (1.76e-2)" 0.0 0.0 0.1 0.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 0.0 0.4 0.5 0.0 0.1 0.0 0.0 0.1 1.8 0.0 2.1 0.0 0.6 0.1 0.1 0.0 0.0 0.1 1.4 0.0 0.0 0.1 0.4 0.5 0.2 0.5 0.3 0.1 0.0 0.2 0.0 0.0 0.4 26.3 0.0 0.0 10.3 2.2 0.0 0.1 0.0 0.0 0.0 9.5 0.0 0.0 7.3 2.9 4.8 11.5 0.6 4.1 0.1 0.0 0.4 1.4 0.0 0.0 1.2 0.0 0.0 6.8 0.0 1.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 3.5 2.0 0.5 16.8 0.0 0.8 0.0 0.0 0.0 20.8 0.0 2.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.1 0.3 0.3 0.0 0.0 0.3 0.2 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.1 2.5 0.6 0.0 0.1 1.1 0.0 0.7 0.0 0.0 IL33 "C9orf26, DKFZp586H0523, DVS27, IL1F11, NF-HEV" ENSG00000137033 "Interleukin 33" O95760 9 6215786-6257983 "Predicted intracellular proteins, Predicted secreted proteins" Transcription Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 120.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 141.8;Fibroblasts: 87.5;Hepatic stellate cells: 499.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "hTERT-RPE1: 53.6;U-2197: 162.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007057, HPA022899, HPA024426" Supported Supported Nucleoplasm,Vesicles "Secreted to blood" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Vesicles "CAB007057: , HPA022899: , HPA024426: AB_1845820" "prognostic favorable (4.42e-4)" "unprognostic (8.36e-2)" "unprognostic (5.67e-3)" "unprognostic (7.67e-3)" "unprognostic (4.27e-1)" "unprognostic (1.63e-1)" "unprognostic (2.59e-3)" "unprognostic (2.66e-3)" "unprognostic (3.18e-1)" "unprognostic (2.05e-1)" "unprognostic (1.43e-1)" "unprognostic (8.08e-2)" "unprognostic (1.58e-3)" "unprognostic (4.70e-3)" "unprognostic (4.10e-2)" "unprognostic (2.64e-1)" "unprognostic (6.85e-3)" 38.7 16.7 9.2 44.6 9.3 0.2 27.2 7.0 12.1 56.2 6.4 24.8 8.8 50.0 15.9 24.5 25.9 33.4 40.9 8.5 10.8 5.0 36.7 53.0 47.1 7.8 8.3 5.0 3.4 3.7 5.7 61.1 7.1 30.0 19.4 2.0 18.9 31.5 6.1 44.0 15.6 50.8 8.3 20.5 33.6 5.8 10.8 13.1 12.6 13.8 43.0 120.7 21.2 8.6 0.0 0.0 0.0 0.0 0.3 1.4 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.1 16.9 0.3 0.0 0.1 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.9 0.7 0.3 0.4 53.6 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.0 0.4 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 162.9 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 9.3 7.0 12.1 8.5 10.8 7.8 8.3 7.1 8.3 10.8 8.6 63.5 6.4 7.2 39.5 1.0 24.2 17.0 73.9 27.3 0.0 9.4 4.1 5.8 4.3 77.8 0.0 0.0 0.0 0.1 2.2 0.0 3.0 0.5 12.4 7.1 141.8 10.7 8.0 0.2 7.9 0.0 87.5 48.4 20.6 1.3 0.0 499.4 5.0 0.1 0.0 0.1 0.2 2.0 20.8 10.2 1.6 20.5 1.7 1.8 1.0 0.0 9.5 0.0 0.5 0.1 12.1 0.2 12.4 0.2 5.2 0.0 0.0 62.1 0.1 0.0 65.5 11.5 0.0 0.4 3.3 48.4 0.1 1.2 0.1 1.1 4.9 IL37 "FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H4, IL-1RP1, IL1F7" ENSG00000125571 "Interleukin 37" Q9NZH6 2 112912971-112918882 "Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 136.8" "Cell type enriched" "Detected in some" 26 "Ionocytes: 73.2" "Cancer enriched" "Detected in some" 6 "lung cancer: 6.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 2.7;PC-3: 5.9;RT4: 3.2" "HPA054371, HPA057950" Uncertain Supported Nucleoplasm,Vesicles "Secreted to blood" NA NA 76700 "Cluster 48: NK-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Vesicles" "HPA054371: AB_2682465, HPA057950: AB_2683561" "unprognostic (1.79e-1)" "unprognostic (1.29e-1)" "unprognostic (1.64e-1)" "unprognostic (3.71e-5)" "unprognostic (1.11e-1)" "unprognostic (2.58e-2)" "unprognostic (1.09e-2)" "unprognostic (1.28e-2)" "unprognostic (9.54e-2)" "unprognostic (8.26e-3)" "unprognostic (3.95e-2)" "unprognostic (1.66e-1)" "unprognostic (8.92e-2)" "unprognostic (1.35e-2)" 0.1 0.0 0.0 0.2 0.0 0.2 16.7 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.1 0.4 136.8 0.1 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.1 0.0 0.0 0.1 0.2 2.7 0.2 0.2 0.2 0.3 0.0 0.2 0.1 0.2 0.1 0.1 0.4 0.8 0.1 0.0 1.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.6 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.8 0.2 0.2 5.9 0.0 0.0 0.0 0.0 3.2 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 73.2 0.0 0.4 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.0 2.8 0.0 0.1 0.0 0.0 0.0 IL6 "BSF2, HGF, HSF, IFNB2, IL-6" ENSG00000136244 "Interleukin 6" P05231 7 22725884-22732002 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Cytokine, Growth factor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 217.6;urinary bladder: 281.3" "Group enriched" "Detected in many" 4 "Adipocytes: 188.5;Endometrial ciliated cells: 163.9;Endothelial cells: 287.4;Fibroblasts: 593.3;Glandular and luminal cells: 322.2;Smooth muscle cells: 449.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 44 "memory B-cell: 3.9;naive B-cell: 4.8" "Lineage enriched" "Detected in single" 48 "B-cells: 4.8" "Group enriched" "Detected in many" 4 "BJ hTERT+: 2214.7;GAMG: 1447.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB023406, CAB072821" Supported Approved Vesicles "Secreted to blood" NA NA 5700 "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB023406: AB_617317, CAB072821: " "unprognostic (1.13e-1)" "unprognostic (1.55e-2)" "unprognostic (1.47e-1)" "unprognostic (1.35e-1)" "unprognostic (3.59e-2)" "unprognostic (9.88e-3)" "unprognostic (1.35e-1)" "unprognostic (3.07e-3)" "unprognostic (3.25e-1)" "unprognostic (2.17e-1)" "unprognostic (2.48e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (1.10e-11)" "unprognostic (2.45e-3)" "unprognostic (2.10e-1)" "unprognostic (4.31e-2)" "unprognostic (7.80e-2)" 217.6 13.9 3.6 30.8 3.8 46.8 31.3 3.7 6.0 4.7 9.2 22.1 1.9 5.7 0.0 34.9 18.9 41.6 55.1 3.8 3.8 17.7 13.0 114.9 9.1 4.0 4.3 6.2 19.5 10.0 38.3 11.3 4.9 16.5 17.3 1.4 12.0 2.0 7.8 7.6 8.3 19.5 3.9 7.0 18.0 1.2 4.7 6.3 14.2 4.1 3.7 281.3 5.7 4.1 0.1 0.0 0.0 0.0 0.7 2.2 7.5 8.9 2214.7 43.2 151.0 0.0 0.6 0.2 71.6 15.2 1447.6 1.7 0.0 0.3 59.9 94.2 0.2 0.0 3.7 0.0 47.3 0.0 0.6 5.6 0.0 413.8 63.1 44.2 18.2 0.0 10.6 0.5 1.9 0.1 0.0 0.3 1.6 0.7 0.5 0.0 0.0 0.0 124.2 0.0 0.0 0.0 144.5 0.1 0.6 7.9 0.1 0.1 14.5 15.2 1.4 28.2 4.7 0.0 27.8 0.4 98.5 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.6 3.8 3.7 6.0 3.8 3.8 4.0 4.3 4.9 3.9 4.7 4.1 188.5 6.4 22.7 0.0 27.0 44.6 3.4 28.5 1.8 0.1 1.4 1.1 1.4 0.0 17.7 3.7 0.0 1.1 0.4 0.1 0.0 9.8 0.4 163.9 44.6 287.4 0.0 0.0 0.0 2.8 4.0 593.3 0.0 322.2 6.3 0.0 3.6 0.1 4.1 0.0 0.0 0.0 0.0 9.3 76.5 0.2 0.0 27.4 40.9 2.8 4.2 0.0 0.0 0.0 0.1 4.3 0.1 0.0 0.9 16.4 0.0 0.0 8.1 0.0 0.0 28.9 449.0 0.0 0.1 0.4 33.4 1.4 8.6 0.2 0.0 20.6 ILVBL "209L8, AHAS, FLJ39061, HACL1L, ILV2H, MGC1269, MGC19535" ENSG00000105135 "IlvB acetolactate synthase like" A1L0T0 19 15114984-15125786 "Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 148.2;Syncytiotrophoblasts: 253.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067682 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Golgi apparatus, Vesicles" "HPA067682: AB_2685885" "unprognostic (5.68e-2)" "unprognostic (1.86e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (1.52e-4)" "unprognostic (8.59e-2)" "unprognostic (1.53e-1)" "unprognostic (4.04e-2)" "unprognostic (2.53e-1)" "unprognostic (3.83e-1)" "unprognostic (5.60e-2)" "unprognostic (1.77e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.91e-8)" "unprognostic (4.65e-2)" "unprognostic (1.68e-1)" "unprognostic (1.40e-1)" "unprognostic (2.40e-1)" 29.7 45.5 22.7 13.9 27.5 15.5 27.5 30.9 25.1 29.7 32.8 46.2 50.1 24.3 14.4 40.9 22.6 25.5 73.7 21.4 25.5 41.6 56.8 19.2 15.5 29.2 25.3 28.3 42.5 65.8 34.4 19.2 26.3 24.2 18.6 13.8 27.7 23.2 18.7 43.4 43.7 13.7 24.8 17.6 41.1 25.5 25.2 10.5 48.0 25.0 10.6 28.5 30.6 32.3 68.8 41.0 34.4 40.7 43.8 29.7 39.6 31.6 42.2 37.2 47.5 65.5 162.1 29.7 61.1 34.2 22.3 50.6 20.9 38.5 10.8 27.5 41.1 43.7 41.3 72.4 70.1 37.2 37.0 44.6 43.9 21.7 28.3 30.4 35.0 29.6 17.9 37.6 29.3 159.0 24.9 29.6 31.9 54.9 58.8 36.0 31.1 46.5 32.3 33.6 28.4 38.3 18.8 81.2 62.1 13.2 37.2 31.2 37.7 55.9 30.7 71.0 45.1 26.1 29.2 15.1 35.9 35.8 43.1 22.7 22.2 5.5 21.1 31.8 24.0 11.9 17.7 22.0 26.3 12.9 22.9 23.6 2.5 23.7 30.3 19.1 20.2 23.3 22.7 27.5 30.9 25.1 21.4 25.5 29.2 25.3 26.3 24.8 25.2 32.3 28.0 25.6 11.7 18.3 12.7 12.7 26.8 53.8 22.2 95.3 18.0 14.9 36.1 62.9 43.0 25.8 27.1 84.2 15.8 67.8 19.6 48.4 6.2 9.9 13.4 23.2 44.4 12.6 4.9 50.6 148.2 21.4 40.2 13.0 11.4 29.0 26.7 59.3 43.2 18.5 8.3 60.6 28.5 12.1 9.5 6.5 25.7 15.8 83.6 5.6 6.8 48.0 7.2 9.0 15.7 32.3 68.4 19.9 17.2 18.6 123.0 50.4 26.1 36.8 19.7 14.7 21.2 20.3 20.8 25.0 16.2 253.4 11.8 48.2 73.2 23.4 INHA ENSG00000123999 "Inhibin subunit alpha" P05111 2 219569162-219575711 "Predicted secreted proteins" "Growth factor, Hormone" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adrenal gland: 75.6;ovary: 104.4;testis: 95.3" "Cell type enhanced" "Detected in some" "Granulosa cells: 254.3;Syncytiotrophoblasts: 331.0;Theca cells: 75.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.5;HEL: 4.5;SK-BR-3: 9.9;SuSa: 4.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB000047, HPA019141, HPA048834" Enhanced Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Golgi apparatus" "CAB000047: AB_322161, HPA019141: AB_1851789, HPA048834: " "unprognostic (8.90e-3)" "unprognostic (2.91e-2)" "unprognostic (2.82e-1)" "unprognostic (7.55e-2)" "unprognostic (1.02e-3)" "unprognostic (1.45e-1)" "unprognostic (3.57e-1)" "unprognostic (9.61e-3)" "unprognostic (4.15e-3)" "unprognostic (6.71e-2)" "unprognostic (3.73e-1)" "unprognostic (7.34e-2)" "prognostic unfavorable (4.03e-5)" "unprognostic (4.85e-2)" "unprognostic (7.20e-2)" "unprognostic (1.93e-1)" "unprognostic (4.43e-2)" 1.2 75.6 3.4 0.2 3.7 0.1 1.4 2.7 4.8 2.0 2.2 0.9 0.2 2.0 2.2 0.8 3.0 0.4 16.3 3.5 3.2 3.1 0.7 0.8 0.1 3.4 2.9 104.4 12.3 0.7 6.6 11.3 3.5 3.1 0.0 1.9 1.5 1.1 0.8 2.1 0.4 0.4 2.5 0.4 0.7 95.3 3.4 0.0 3.3 0.0 0.0 1.0 1.8 3.0 0.4 0.2 0.0 1.9 0.6 0.1 3.5 0.3 0.2 0.5 0.2 0.3 3.2 0.0 0.2 0.7 0.5 2.0 0.2 0.5 0.0 0.0 0.6 4.5 1.8 2.4 0.3 0.0 0.0 0.6 0.8 0.0 0.5 1.4 0.0 0.0 2.8 0.0 0.0 2.3 0.0 0.1 1.2 0.1 0.9 0.1 0.2 0.0 0.5 0.2 0.3 0.8 1.1 9.9 0.3 4.9 0.5 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 3.7 2.7 4.8 3.5 3.2 3.4 2.9 3.5 2.5 3.4 3.0 0.1 0.0 0.0 5.9 0.0 0.0 0.1 0.8 0.0 2.7 0.3 0.3 2.2 0.0 0.1 7.3 2.1 11.8 0.0 0.0 0.0 2.8 0.8 0.5 0.5 0.2 0.0 0.0 5.9 8.9 35.5 1.2 0.0 0.5 0.0 254.3 0.7 0.1 2.6 6.7 6.9 0.0 0.0 0.3 0.0 5.0 4.1 0.2 0.0 0.0 0.0 3.7 0.0 1.0 0.4 2.1 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 1.5 3.4 0.6 0.0 0.0 331.0 0.0 75.6 0.0 0.0 INHBE "activin, MGC4638" ENSG00000139269 "Inhibin subunit beta E" P58166 12 57452323-57459280 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor, Hormone" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 88 "liver: 148.4" "Cell type enriched" "Detected in single" 43 "Hepatocytes: 35.0" "Cancer enriched" "Detected in some" 27 "liver cancer: 34.4" "Region enhanced" "Detected in some" "cerebellum: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 50.8;Karpas-707: 79.1;RH-30: 36.9;U-266/70: 263.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016843, CAB034017" Enhanced Supported Vesicles "Secreted to blood" NA NA 3500000 "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 2: Hepatocytes - Metabolism" Vesicles "CAB034017: AB_2233745, HPA016843: AB_1851796" "unprognostic (7.34e-2)" "unprognostic (6.73e-2)" "unprognostic (3.45e-1)" "unprognostic (4.69e-5)" "unprognostic (2.61e-1)" "unprognostic (2.50e-1)" "unprognostic (3.13e-1)" "unprognostic (1.24e-1)" "unprognostic (8.79e-3)" "unprognostic (1.44e-1)" "unprognostic (3.22e-1)" "unprognostic (2.70e-1)" "prognostic unfavorable (5.66e-8)" "unprognostic (4.09e-3)" "unprognostic (1.56e-1)" "unprognostic (3.57e-2)" "unprognostic (7.52e-3)" 0.0 0.0 0.0 0.1 0.1 0.3 0.0 1.6 0.3 0.2 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.3 148.4 0.1 0.1 0.9 0.0 0.0 0.9 0.1 1.0 0.0 1.1 0.3 0.0 0.1 0.0 0.0 1.5 0.1 0.2 0.0 0.0 0.3 0.0 0.2 0.1 0.0 1.4 0.5 0.0 0.2 0.1 0.2 0.2 0.4 0.3 0.5 0.0 0.5 0.3 2.9 7.8 0.2 9.2 0.4 0.1 4.0 1.9 0.7 0.2 0.4 1.8 0.0 1.2 18.3 0.2 0.1 0.3 11.9 50.8 2.3 2.4 4.9 5.3 1.2 11.4 0.4 0.0 1.8 5.0 79.1 0.0 0.0 0.2 0.2 0.5 0.1 0.3 0.2 36.9 8.8 0.0 0.1 19.5 0.9 0.0 0.0 7.6 0.3 0.6 8.7 0.3 0.2 4.0 0.1 0.6 263.5 9.2 3.8 1.5 0.4 0.3 0.9 0.1 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.1 0.2 0.0 0.0 0.0 0.1 1.6 0.3 0.1 0.1 0.9 0.0 1.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 INKA1 "C3orf54, FAM212A" ENSG00000185614 "Inka box actin regulator 1" 3 49803261-49805030 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "skin 1: 24.1" "Cell type enhanced" "Detected in some" "Adipocytes: 19.9;Breast myoepithelial cells: 9.7;Endothelial cells: 8.4;Hofbauer cells: 54.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 59.6;memory B-cell: 65.9;naive B-cell: 64.4" "Group enriched" "Detected in many" 7 "B-cells: 65.9;granulocytes: 59.6" "Cell line enhanced" "Detected in many" "HEL: 68.5;HMC-1: 45.1;NB-4: 38.5;THP-1: 42.1;U-937: 34.9" "Low region specificity" "Detected in all" HPA041879 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 32: U-937 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Vesicles" "HPA041879: AB_10797269" "unprognostic (1.36e-1)" "unprognostic (2.99e-2)" "unprognostic (6.97e-2)" "unprognostic (7.95e-2)" "unprognostic (1.34e-1)" "prognostic favorable (1.96e-4)" "unprognostic (2.70e-2)" "unprognostic (4.35e-2)" "unprognostic (7.28e-2)" "unprognostic (2.94e-1)" "unprognostic (3.35e-3)" "unprognostic (4.61e-2)" "unprognostic (1.90e-3)" "unprognostic (4.95e-2)" "unprognostic (3.90e-2)" "unprognostic (1.45e-1)" "unprognostic (1.40e-2)" 5.1 2.3 4.8 2.0 5.0 3.5 4.1 5.2 7.6 6.2 2.8 3.2 0.8 4.7 1.4 19.7 2.8 1.5 5.2 5.3 5.5 5.8 1.1 5.4 4.1 6.2 5.3 2.2 1.3 0.5 2.1 3.1 5.7 6.4 0.5 0.2 4.9 2.1 11.7 24.1 4.3 1.8 5.8 6.7 2.4 2.9 6.5 1.6 2.1 2.3 3.9 5.5 10.3 7.0 1.3 1.1 1.5 1.1 1.8 4.1 0.0 3.0 1.9 1.4 1.7 0.1 0.0 14.9 0.4 2.2 1.5 8.7 0.5 10.4 0.1 2.6 0.0 68.5 0.7 0.2 2.6 10.4 45.1 5.4 14.5 2.9 2.6 0.9 6.1 1.0 4.7 1.2 1.2 0.6 0.9 38.5 1.1 0.0 5.8 13.9 0.8 3.3 0.1 16.9 0.8 5.3 2.7 0.5 1.5 0.4 0.3 42.1 3.8 7.3 0.9 3.4 1.3 1.7 1.7 1.2 3.2 34.9 1.8 59.6 2.4 11.6 1.3 5.9 0.3 65.9 1.5 1.8 0.7 64.4 2.2 3.6 1.3 0.0 8.5 9.3 1.6 6.4 4.8 5.0 5.2 7.6 5.3 5.5 6.2 5.3 5.7 5.8 6.5 7.0 19.9 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 1.0 9.7 0.0 0.0 0.0 0.0 0.0 0.4 1.0 0.0 0.0 0.7 0.0 0.5 1.6 8.4 0.0 0.0 0.0 1.2 0.7 3.0 0.0 0.1 0.0 0.1 0.0 0.0 54.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 3.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.1 0.4 0.5 0.0 0.0 INKA2 "C1orf183, FAM212B, FLJ31105" ENSG00000197852 "Inka box actin regulator 2" Q9NTI7 1 111680630-111755824 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in single" 8 "Hofbauer cells: 4.0" "Cancer enhanced" "Detected in many" "glioma: 6.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 13 "neutrophil: 25.2" "Lineage enriched" "Detected in many" 13 "granulocytes: 25.2" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 35.6;U-87 MG: 73.0;WM-115: 28.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027809, HPA027810, HPA027811" Approved Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 47: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 33: Fibroblasts - ECM organization" Nucleoplasm "Nucleoli, Vesicles" "HPA027809: AB_10599616, HPA027810: , HPA027811: AB_10600872" "unprognostic (1.92e-1)" "unprognostic (9.70e-3)" "unprognostic (1.84e-1)" "unprognostic (1.85e-2)" "unprognostic (2.81e-2)" "prognostic favorable (4.51e-5)" "unprognostic (9.96e-4)" "unprognostic (1.15e-1)" "unprognostic (1.36e-2)" "unprognostic (9.50e-3)" "unprognostic (9.92e-5)" "unprognostic (8.66e-2)" "unprognostic (1.31e-3)" "unprognostic (2.84e-1)" "unprognostic (1.42e-1)" "unprognostic (3.03e-3)" "unprognostic (5.07e-2)" 7.4 1.0 8.8 3.0 13.0 2.9 4.0 5.0 16.7 2.3 2.0 3.5 1.2 3.9 1.7 6.6 5.1 2.9 13.8 14.6 4.0 2.7 0.9 4.8 1.0 4.3 3.8 2.1 1.2 2.3 0.7 6.1 3.9 3.0 2.4 1.4 2.3 4.0 7.8 5.5 2.4 5.8 3.5 5.3 3.8 2.6 4.0 2.1 2.5 8.9 1.7 2.8 3.4 9.8 2.5 2.3 5.1 3.2 20.5 7.3 1.7 1.8 4.0 3.3 7.8 4.1 0.1 2.0 0.9 1.8 1.6 2.2 2.2 4.9 3.2 4.6 1.9 15.0 1.8 4.0 8.1 1.1 2.3 6.0 20.9 35.6 1.6 0.9 8.9 2.6 0.1 3.3 5.3 2.8 1.1 1.2 1.2 2.4 2.0 2.2 19.4 0.7 0.9 3.5 10.2 3.4 1.1 0.1 9.8 5.6 2.8 3.3 3.5 7.1 11.4 3.9 1.5 20.7 3.8 2.1 73.0 4.5 28.0 0.2 1.8 1.4 0.0 1.4 0.0 0.2 0.1 0.1 1.0 0.4 0.0 0.0 25.2 0.6 2.0 0.5 0.0 0.6 8.8 13.0 5.0 16.7 14.6 4.0 4.3 3.8 3.9 3.5 4.0 9.8 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 INMT ENSG00000241644 "Indolethylamine N-methyltransferase" O95050 7 30697985-30757602 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Detoxification "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 205.8" "Group enriched" "Detected in many" 7 "Endothelial cells: 150.4;Hepatic stellate cells: 268.4;Leydig cells: 285.2;Peritubular cells: 455.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 22.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "CACO-2: 16.7;HHSteC: 6.7" HPA061343 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Vesicles" "HPA061343: AB_2684483" "unprognostic (1.70e-1)" "unprognostic (4.36e-2)" "unprognostic (5.26e-2)" "unprognostic (6.78e-3)" "unprognostic (1.59e-1)" "unprognostic (3.39e-4)" "prognostic favorable (5.72e-4)" "unprognostic (3.08e-2)" "unprognostic (3.94e-2)" "unprognostic (1.59e-1)" "unprognostic (8.51e-2)" "unprognostic (9.07e-2)" "unprognostic (4.97e-2)" "unprognostic (1.62e-2)" "unprognostic (1.43e-2)" "unprognostic (9.71e-2)" "unprognostic (1.58e-2)" 64.5 51.2 3.1 2.7 6.0 0.7 10.2 7.9 13.1 6.4 9.3 9.5 2.8 16.0 25.4 15.0 43.8 8.3 75.6 7.6 8.7 20.0 23.3 205.8 7.6 9.6 6.0 17.7 11.3 5.7 7.8 33.7 5.6 29.6 4.6 0.5 9.1 48.0 14.4 4.2 8.5 25.7 2.5 13.0 12.7 15.8 4.8 1.7 21.3 13.2 4.0 11.1 7.2 16.6 0.0 0.1 0.0 0.1 1.5 2.1 0.3 0.2 2.1 0.0 0.0 16.7 0.1 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 6.7 0.1 0.3 0.8 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.2 0.2 0.1 0.0 0.4 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.5 0.1 0.6 0.0 0.6 0.1 0.0 1.0 0.0 0.6 0.2 0.0 0.7 0.3 0.0 0.2 0.1 0.3 1.6 0.2 0.2 0.2 0.1 0.1 0.3 0.1 0.1 0.1 0.4 0.2 0.2 0.8 0.5 0.1 0.3 0.1 0.2 3.1 6.0 7.9 13.1 7.6 8.7 9.6 6.0 5.6 2.5 4.8 16.6 39.4 0.0 3.6 0.0 1.0 2.2 0.1 0.0 1.2 0.0 0.4 0.6 10.0 7.2 2.5 0.0 0.0 0.7 0.3 0.0 0.0 0.0 2.3 0.1 0.8 150.4 1.2 8.0 0.0 0.0 0.4 38.2 0.0 0.0 0.0 0.9 268.4 5.1 0.8 0.0 0.0 0.2 0.0 16.6 4.4 16.0 285.2 0.7 3.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 455.5 1.5 0.2 0.0 0.1 0.7 0.0 32.9 5.0 19.6 1.3 1.3 0.4 2.3 1.8 1.3 0.2 0.0 0.4 INPP5F "hSac2, KIAA0966, SAC2" ENSG00000198825 "Inositol polyphosphate-5-phosphatase F" Q9Y2H2 10 119726042-119829147 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 135.3" "Cell type enhanced" "Detected in all" "Excitatory neurons: 79.5;Inhibitory neurons: 130.5;Late spermatids: 88.6;Oligodendrocytes: 70.5" "Cancer enhanced" "Detected in all" "testis cancer: 27.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 91.4;SK-MEL-30: 149.0;SuSa: 181.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042605 Supported Vesicles NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA042605: AB_10793886" "unprognostic (2.65e-2)" "unprognostic (3.23e-1)" "unprognostic (3.42e-2)" "unprognostic (5.84e-2)" "unprognostic (1.87e-2)" "unprognostic (1.57e-3)" "unprognostic (2.46e-3)" "unprognostic (2.21e-1)" "unprognostic (1.12e-1)" "unprognostic (8.09e-2)" "unprognostic (2.09e-1)" "unprognostic (6.46e-2)" "unprognostic (7.78e-2)" "unprognostic (1.02e-1)" "unprognostic (9.91e-2)" "unprognostic (2.96e-2)" "unprognostic (6.21e-2)" 9.9 16.8 53.8 9.9 49.4 4.7 7.6 45.3 63.9 15.7 10.1 15.5 4.6 15.4 22.8 9.3 8.3 6.9 5.9 50.6 135.3 10.5 3.2 9.1 10.7 71.2 57.3 12.3 6.7 7.4 57.1 10.9 75.0 10.9 8.0 32.9 10.8 10.0 11.0 13.7 9.5 13.2 50.3 7.5 8.6 14.8 62.7 7.0 10.5 3.8 13.0 9.2 12.5 55.2 13.5 8.2 91.4 14.3 6.9 10.6 8.5 18.4 9.3 8.4 8.4 12.0 15.2 8.3 7.6 19.7 10.6 14.4 7.9 9.8 11.9 6.0 10.3 6.5 3.9 11.0 13.5 4.4 19.0 9.7 8.6 14.2 13.5 15.7 23.2 6.1 5.7 13.8 20.8 7.0 5.5 15.7 9.2 9.9 12.0 7.0 18.8 2.3 12.5 5.3 6.5 70.2 19.8 7.2 149.0 181.5 4.3 3.4 19.6 9.9 12.2 11.0 17.5 15.2 7.7 4.5 11.0 12.8 32.3 0.9 3.4 1.3 1.0 3.0 1.3 6.7 2.2 1.3 6.2 9.1 2.2 1.1 0.8 3.4 3.6 1.4 5.3 1.9 53.8 49.4 45.3 63.9 50.6 135.3 71.2 57.3 75.0 50.3 62.7 55.2 7.8 6.4 4.8 52.5 21.5 9.1 11.7 7.5 10.2 24.2 6.9 9.5 5.4 1.5 7.8 12.9 16.7 9.3 7.9 15.1 11.7 3.6 58.7 4.3 18.3 8.6 1.2 5.2 79.5 4.5 10.6 7.9 5.1 6.9 2.5 9.7 4.2 3.5 9.9 42.1 130.5 5.6 10.2 6.0 27.8 88.6 5.3 13.1 19.6 34.7 16.3 21.7 6.2 52.8 70.5 6.8 6.6 3.8 4.7 8.2 6.5 24.7 4.0 21.6 6.6 7.8 13.8 22.4 41.0 13.1 10.4 13.3 7.7 19.3 6.5 13.1 INSIG1 "CL-6, MGC1405" ENSG00000186480 "Insulin induced gene 1" O15503 7 155297776-155310235 "Plasma proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 563.4" "Cell type enriched" "Detected in all" 4 "Langerhans cells: 4121.3" "Cancer enriched" "Detected in all" 5 "liver cancer: 142.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "intermediate monocyte: 272.8;non-classical monocyte: 500.8" "Lineage enriched" "Detected in all" 6 "monocytes: 500.8" "Cell line enhanced" "Detected in many" "Karpas-707: 1228.9;RPMI-8226: 605.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071524 Uncertain Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA071524: " "unprognostic (8.11e-2)" "unprognostic (3.22e-1)" "unprognostic (2.91e-1)" "unprognostic (1.47e-1)" "unprognostic (9.23e-2)" "unprognostic (3.83e-2)" "unprognostic (2.05e-2)" "unprognostic (3.06e-1)" "unprognostic (1.60e-2)" "unprognostic (1.52e-1)" "unprognostic (4.64e-2)" "unprognostic (2.12e-1)" "unprognostic (1.26e-1)" "unprognostic (1.85e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (9.62e-4)" "unprognostic (4.97e-2)" 79.2 37.3 25.3 35.4 36.9 45.5 37.4 47.1 39.1 25.5 58.0 29.8 53.0 19.5 31.8 40.1 17.6 31.6 21.0 30.2 40.9 45.6 563.4 43.2 30.9 61.1 51.7 24.0 111.7 17.4 18.9 34.2 62.8 62.6 26.4 40.5 70.9 11.3 9.0 42.5 35.2 20.3 36.6 19.0 61.1 34.4 36.5 40.4 12.5 12.0 25.3 36.7 23.3 86.3 158.9 29.0 76.8 48.1 200.6 265.5 41.9 12.5 179.1 36.9 242.6 18.1 225.2 104.0 35.7 98.2 282.2 83.9 53.1 92.6 43.3 32.3 155.5 28.6 51.7 0.0 99.0 49.3 448.7 165.6 50.4 281.8 25.8 27.3 49.8 202.8 53.2 1228.9 47.9 82.2 238.7 128.6 80.0 30.4 20.4 43.5 0.2 605.1 291.6 77.8 57.2 45.5 41.6 29.9 67.8 28.7 29.0 162.0 56.3 40.5 11.8 77.2 33.3 296.8 57.4 93.3 177.6 187.2 38.2 21.3 29.7 13.4 49.3 272.8 25.5 46.5 32.8 41.9 78.5 60.2 32.6 36.7 62.6 27.5 500.8 44.7 77.0 85.2 25.3 36.9 47.1 39.1 30.2 40.9 61.1 51.7 62.8 36.6 36.5 86.3 91.4 41.7 121.5 39.8 100.5 140.2 59.4 148.2 74.6 16.5 58.0 31.6 43.6 35.8 114.4 40.5 10.4 47.7 79.0 129.1 17.6 52.0 21.2 30.8 11.6 135.6 126.8 38.3 11.1 140.4 189.0 120.4 57.6 67.4 60.4 18.1 33.2 828.9 46.9 38.7 16.9 91.5 185.1 63.6 4121.3 9.7 15.8 381.0 247.3 7.5 29.6 88.7 34.0 17.1 61.8 53.6 86.6 18.4 100.1 180.4 29.1 9.4 68.3 18.1 19.7 36.3 62.0 33.6 45.0 135.8 155.3 130.4 108.2 20.6 48.0 158.5 INSL4 EPIL ENSG00000120211 "Insulin like 4" Q14641 9 5231419-5235304 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "placenta: 15.9" "Cell type enriched" "Detected in some" 10 "Syncytiotrophoblasts: 3575.7" "Cancer enhanced" "Detected in some" "lung cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "A549: 24.6" HPA065145 Approved Vesicles "Secreted to blood" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA065145: " "unprognostic (9.77e-2)" "unprognostic (2.02e-1)" "unprognostic (4.66e-1)" "unprognostic (7.74e-2)" 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 24.6 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.4 0.0 2.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 325.8 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 26.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 38.2 0.0 0.0 0.0 0.0 0.0 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3575.7 0.0 0.0 0.0 0.0 INSR CD220 ENSG00000171105 "Insulin receptor" P06213 19 7112255-7294414 "CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Carbohydrate metabolism" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 9.8;granulocytes: 5.9;monocytes: 12.5" "Cell line enhanced" "Detected in many" "Karpas-707: 54.9;U-266/70: 40.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036302, HPA036303" Uncertain Approved "Vesicles,Plasma membrane" NA Yes 190000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Plasma membrane" "HPA036302: AB_2675048, HPA036303: " "unprognostic (4.64e-2)" "unprognostic (2.42e-1)" "unprognostic (9.65e-3)" "unprognostic (9.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.15e-2)" "unprognostic (2.58e-1)" "unprognostic (5.09e-2)" "unprognostic (1.97e-1)" "unprognostic (3.05e-1)" "unprognostic (9.29e-2)" "unprognostic (1.86e-1)" "unprognostic (6.33e-2)" "unprognostic (3.45e-3)" "unprognostic (2.43e-1)" "unprognostic (2.75e-1)" "unprognostic (8.82e-2)" 13.0 22.6 12.5 2.8 16.8 5.6 13.0 17.3 12.8 14.6 18.8 15.0 10.0 18.4 6.3 4.1 16.9 8.2 26.3 10.0 12.2 21.8 33.0 7.2 2.3 18.3 16.3 39.9 64.2 13.0 16.3 7.4 18.7 15.2 10.4 6.5 16.9 9.9 23.5 11.5 12.2 11.5 14.1 48.2 12.5 5.4 16.6 2.7 14.5 13.3 3.5 12.3 9.2 22.5 6.2 3.2 3.6 5.7 18.8 6.1 11.1 3.5 2.9 1.6 1.6 8.4 7.0 9.0 8.2 6.8 4.0 1.6 8.9 1.4 1.2 0.0 6.4 0.0 2.3 22.6 8.2 4.3 6.7 10.0 4.5 0.2 4.9 4.2 3.8 4.8 9.5 54.9 1.8 3.2 3.1 7.8 3.3 3.8 5.2 29.0 2.1 7.6 0.1 27.8 6.6 5.2 6.5 3.8 3.3 6.4 1.4 21.6 3.6 3.4 2.1 8.2 5.1 40.4 23.9 20.2 4.3 7.3 0.0 2.7 8.6 5.9 0.2 8.8 0.3 0.8 0.3 0.1 9.8 1.1 0.7 0.1 1.9 1.0 12.5 8.2 0.0 1.6 12.5 16.8 17.3 12.8 10.0 12.2 18.3 16.3 18.7 14.1 16.6 22.5 75.6 48.1 34.7 64.9 10.6 64.9 63.6 34.7 8.0 40.4 134.0 76.2 92.1 137.2 83.3 62.5 79.2 17.8 6.7 124.1 15.6 55.1 4.7 26.8 106.8 123.9 163.6 25.0 68.3 78.7 53.7 43.7 20.4 42.1 3.8 168.4 255.2 246.0 9.2 38.7 100.8 97.3 32.6 49.0 31.1 9.0 96.3 35.0 51.6 62.8 24.2 31.6 0.0 62.8 183.5 50.7 68.8 245.3 21.8 107.9 122.9 114.1 65.3 23.6 59.2 37.6 44.2 5.2 3.6 3.2 68.8 38.3 4.7 81.4 65.2 130.0 INTS13 "ASUN, C12orf11, FLJ10637, Mat89Bb, NET48, SPATA30" ENSG00000064102 "Integrator complex subunit 13" Q9NVM9 12 26905181-26938326 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 22.4;Endometrial stromal cells: 16.7;Extravillous trophoblasts: 16.1;Theca cells: 18.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039543, HPA040109, HPA073020" Uncertain Enhanced "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nuclear bodies, Vesicles" "HPA039543: AB_10795150, HPA040109: , HPA073020: " "unprognostic (2.09e-1)" "unprognostic (8.48e-3)" "unprognostic (2.75e-2)" "unprognostic (1.40e-3)" "unprognostic (3.94e-2)" "unprognostic (3.01e-2)" "prognostic unfavorable (1.17e-10)" "unprognostic (5.22e-3)" "unprognostic (5.28e-2)" "unprognostic (1.67e-2)" "unprognostic (1.78e-3)" "unprognostic (3.75e-3)" "prognostic unfavorable (3.16e-6)" "unprognostic (1.02e-1)" "unprognostic (8.51e-2)" "unprognostic (4.37e-2)" "unprognostic (4.78e-2)" 9.9 21.4 9.3 11.3 13.4 17.2 11.7 13.2 14.3 10.4 8.1 9.7 9.9 10.0 10.3 14.6 8.5 8.2 12.2 9.5 11.6 13.2 15.1 7.9 16.7 15.4 12.0 8.0 11.5 8.0 8.1 10.0 14.8 8.5 10.7 21.8 9.0 7.0 19.0 11.8 8.5 11.9 13.9 12.9 15.4 12.1 12.2 18.6 9.9 18.1 16.8 12.8 10.6 20.0 33.4 38.1 21.5 46.4 30.5 48.9 30.9 44.9 27.4 43.3 48.1 58.4 43.1 82.7 45.0 25.1 40.6 46.2 56.1 43.6 72.8 39.5 37.4 66.7 44.5 44.9 53.9 110.6 38.4 26.3 32.2 69.5 147.0 53.5 56.8 35.6 71.5 31.9 46.7 40.9 57.9 197.8 94.6 45.6 68.9 40.8 62.3 114.0 36.4 31.0 17.8 16.7 39.1 30.6 47.4 72.8 42.6 23.4 36.5 50.1 36.2 85.6 55.1 15.6 19.6 119.4 33.1 75.8 36.2 7.8 8.1 7.8 14.6 5.7 22.1 9.7 18.2 18.2 9.9 11.3 12.7 15.7 2.5 25.9 5.2 6.7 28.1 10.5 9.3 13.4 13.2 14.3 9.5 11.6 15.4 12.0 14.8 13.9 12.2 20.0 7.2 22.4 7.8 0.0 2.7 0.0 0.0 0.0 0.0 0.0 7.9 8.3 0.0 0.0 2.5 5.5 0.0 11.8 8.8 0.0 3.9 13.7 0.0 8.7 16.7 3.9 0.0 0.0 0.0 11.9 16.1 8.3 0.0 8.2 7.6 13.9 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 5.7 0.0 0.0 0.0 0.0 13.7 0.0 0.0 1.6 0.0 0.0 11.6 2.9 0.0 0.0 0.0 6.6 0.0 0.0 0.0 0.0 13.1 6.5 18.5 0.0 0.0 IPO9 "FLJ10402, Imp9" ENSG00000198700 "Importin 9" Q96P70 1 201829149-201884291 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059540 Approved Vesicles,Cytosol "Intracellular and membrane" NA NA 70000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" Cytosol Vesicles "HPA059540: " "unprognostic (1.20e-1)" "unprognostic (1.37e-1)" "unprognostic (7.44e-3)" "unprognostic (2.02e-2)" "unprognostic (1.13e-1)" "unprognostic (4.99e-2)" "prognostic unfavorable (4.11e-5)" "unprognostic (8.92e-3)" "unprognostic (2.23e-3)" "unprognostic (2.52e-1)" "unprognostic (1.05e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (2.86e-4)" "unprognostic (5.05e-2)" "unprognostic (2.57e-1)" "unprognostic (3.13e-2)" "prognostic unfavorable (5.78e-4)" 17.0 18.2 17.8 12.0 17.8 10.1 16.5 18.0 22.5 18.9 16.4 15.9 9.2 19.2 18.2 15.7 15.2 9.2 15.9 18.8 17.6 17.4 26.9 17.9 13.7 17.3 16.7 17.2 17.9 14.8 20.7 14.5 16.8 17.5 13.9 23.7 12.3 10.8 14.0 17.7 15.1 16.7 15.0 19.6 14.3 14.4 17.8 16.2 19.3 10.7 16.7 16.6 15.0 17.1 45.4 46.9 63.0 51.4 35.7 24.1 47.1 34.2 34.3 55.6 53.8 75.6 38.4 26.8 18.9 32.9 48.8 41.0 43.0 47.2 47.9 24.5 38.1 20.0 75.2 57.2 27.2 26.2 31.4 26.7 21.3 60.2 48.5 37.1 56.7 36.0 40.5 24.6 40.4 45.1 30.5 34.2 63.4 40.6 15.2 32.2 65.8 26.6 30.7 71.0 53.3 60.5 37.5 58.7 30.8 96.6 43.1 32.8 31.1 52.1 46.6 29.5 63.5 18.1 12.0 31.5 25.9 30.5 39.8 10.1 10.1 8.7 9.9 13.2 8.6 9.5 9.5 10.9 12.6 8.5 7.6 8.3 2.3 10.2 13.8 6.6 9.5 7.8 17.8 17.8 18.0 22.5 18.8 17.6 17.3 16.7 16.8 15.0 17.8 17.1 25.7 22.4 45.6 48.0 22.1 15.8 14.9 14.3 13.6 57.9 14.5 14.7 23.6 10.0 20.4 7.3 60.5 27.8 17.6 7.5 1.9 16.9 8.0 9.2 28.9 27.3 11.3 28.6 60.1 18.7 20.8 25.4 16.3 11.2 11.4 32.6 23.2 18.1 19.5 75.7 60.7 16.3 10.2 17.6 21.5 8.8 20.2 13.3 14.2 36.5 21.6 38.1 26.8 46.8 50.6 17.6 10.6 28.2 18.2 16.4 8.9 9.0 10.5 56.5 39.5 35.4 26.1 42.0 37.3 16.4 14.2 22.6 17.0 26.0 17.0 12.5 IQCC FLJ10547 ENSG00000160051 "IQ motif containing C" Q4KMZ1 1 32205671-32208682 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 22.2;Spermatogonia: 11.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028602, HPA028686" Approved Approved Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 14: REH - Unknown function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "HPA028602: AB_10600298, HPA028686: AB_10601985" "unprognostic (1.45e-3)" "unprognostic (4.25e-3)" "unprognostic (2.07e-1)" "unprognostic (1.76e-1)" "unprognostic (2.56e-1)" "unprognostic (4.00e-3)" "unprognostic (7.81e-6)" "prognostic favorable (5.65e-4)" "unprognostic (4.97e-2)" "unprognostic (2.97e-2)" "prognostic favorable (8.23e-5)" "unprognostic (2.00e-1)" "unprognostic (3.28e-1)" "unprognostic (3.12e-3)" "prognostic favorable (3.79e-4)" "unprognostic (4.22e-2)" "unprognostic (1.66e-1)" 1.0 1.8 2.3 1.0 2.7 2.1 2.1 3.6 3.1 1.5 5.3 1.5 0.9 1.5 4.4 1.2 3.5 1.4 1.2 2.6 2.2 1.7 0.8 1.1 1.6 2.1 2.2 2.1 2.4 2.9 3.6 1.1 1.9 1.6 1.5 2.8 1.8 1.7 1.6 2.3 1.2 1.2 2.0 1.3 1.9 8.8 2.4 2.1 3.4 1.3 1.7 1.2 1.3 2.4 6.6 2.3 5.1 4.8 0.9 1.9 3.3 3.7 4.2 7.8 7.2 5.3 5.7 2.3 3.9 1.1 1.3 5.5 5.4 3.3 6.5 3.2 5.6 4.2 5.2 2.3 1.2 4.5 2.7 1.3 3.5 6.9 3.1 2.9 1.6 8.9 7.6 0.5 3.5 4.6 7.7 4.7 3.3 3.6 4.9 10.4 3.1 5.5 2.9 2.3 7.3 2.9 7.4 4.2 4.1 4.7 5.1 4.5 2.2 2.8 5.1 4.1 6.2 2.9 2.1 2.1 3.9 4.2 5.9 0.8 0.3 0.1 1.1 0.4 1.0 2.3 1.2 0.9 0.7 0.8 1.3 0.7 1.1 1.6 0.4 1.0 1.6 0.5 2.3 2.7 3.6 3.1 2.6 2.2 2.1 2.2 1.9 2.0 2.4 2.4 1.7 0.0 2.3 2.0 0.7 0.3 1.0 0.9 1.2 5.4 2.9 1.9 1.6 7.2 0.4 3.7 6.2 1.9 2.1 2.3 3.9 1.8 1.7 8.5 2.0 1.6 3.0 7.0 2.0 1.4 1.6 2.0 1.5 2.1 1.3 2.1 0.0 0.4 0.9 6.7 1.9 4.8 0.0 0.0 1.1 1.8 1.2 0.7 0.0 0.0 1.2 2.6 1.0 0.5 1.3 1.1 1.8 2.6 0.6 0.6 0.9 0.6 3.6 8.6 0.0 2.4 1.7 22.2 11.6 1.1 0.9 1.0 1.3 1.8 2.0 0.3 IQGAP2 ENSG00000145703 "IQ motif containing GTPase activating protein 2" Q13576 5 76403285-76708132 "Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 113.1" "Cell type enhanced" "Detected in many" "Early spermatids: 1011.9;Late spermatids: 351.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 21.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 74.2;Hep G2: 61.7;HMC-1: 211.8;RPMI-8226: 81.6;U-937: 57.0" "Region enhanced" "Detected in many" "hippocampal formation: 30.5" "Low region specificity" "Detected in all" "CAB004241, HPA037403, HPA037404" Uncertain Approved "Vesicles,Plasma membrane" NA NA 3700000 "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "CAB004241: AB_2125909, HPA037403: AB_2675459, HPA037404: AB_2675460" "unprognostic (9.46e-2)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (1.48e-1)" "unprognostic (9.03e-3)" "unprognostic (8.85e-2)" "prognostic favorable (5.65e-4)" "unprognostic (5.96e-2)" "unprognostic (1.14e-1)" "unprognostic (2.34e-1)" "unprognostic (2.14e-1)" "unprognostic (1.41e-1)" "prognostic favorable (9.44e-12)" "unprognostic (3.29e-2)" "unprognostic (9.89e-2)" "unprognostic (1.52e-2)" "unprognostic (1.27e-2)" 7.9 12.2 0.8 11.7 0.6 25.0 27.1 0.5 0.7 19.6 2.4 25.7 56.5 3.3 9.5 2.8 3.4 18.6 2.9 0.4 0.9 35.2 113.1 9.9 14.4 2.2 2.5 8.9 25.7 44.3 1.1 30.7 1.9 15.2 23.0 23.9 34.6 15.4 0.3 2.7 31.4 4.3 1.4 13.2 39.1 51.1 2.4 7.3 28.6 1.3 8.2 6.5 1.5 2.4 0.0 9.6 31.5 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 74.2 0.1 0.7 2.7 0.0 2.7 0.2 12.1 0.0 0.1 8.6 12.0 27.6 6.8 61.7 0.2 15.7 211.8 0.0 0.0 0.0 0.0 0.0 1.2 14.9 24.6 21.4 0.0 0.0 13.5 42.4 14.8 25.4 0.3 4.9 0.1 81.6 0.0 0.1 0.6 3.2 17.3 0.9 0.1 31.4 0.0 9.3 0.4 0.0 0.5 0.0 0.3 19.8 0.0 18.7 0.1 57.0 3.0 21.3 3.1 1.9 4.5 2.5 3.7 0.5 4.7 3.9 2.9 0.2 1.8 3.3 6.0 4.3 3.4 7.7 6.2 1.4 0.8 0.6 0.5 0.7 0.4 0.9 2.2 2.5 1.9 1.4 2.4 2.4 9.1 12.8 12.2 0.7 27.3 4.7 21.5 2.4 0.0 6.7 68.9 34.5 3.5 107.2 9.1 35.0 108.4 14.2 230.3 96.2 7.9 44.5 1011.9 43.8 3.3 7.7 9.1 76.3 2.3 66.7 1.2 22.0 99.4 37.5 94.9 8.7 18.5 235.7 65.9 1.7 19.0 52.9 61.1 132.6 63.3 351.0 7.5 141.3 16.0 47.8 63.4 14.0 114.4 0.5 1.1 18.7 37.5 5.3 148.3 21.5 87.1 65.2 16.1 121.8 0.0 3.9 3.5 25.5 11.4 1.2 3.8 7.3 112.1 82.7 43.7 6.5 IQSEC1 "ARF-GEP100, BRAG2, GEP100, KIAA0763" ENSG00000144711 "IQ motif and Sec7 domain ArfGEF 1" Q6DN90 3 12897043-13283281 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 183.0;Cone photoreceptor cells: 193.9;Excitatory neurons: 191.3;Horizontal cells: 235.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 66.5;U-266/84: 64.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038143, HPA038144" Uncertain Supported "Nucleoli,Nucleoli rim,Vesicles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Nucleoli rim, Vesicles" "HPA038143: AB_10697241, HPA038144: AB_2675860" "prognostic unfavorable (3.03e-5)" "unprognostic (1.80e-1)" "unprognostic (6.32e-2)" "unprognostic (3.01e-1)" "unprognostic (8.19e-3)" "unprognostic (2.64e-3)" "unprognostic (5.60e-2)" "unprognostic (1.67e-1)" "unprognostic (3.00e-1)" "unprognostic (1.14e-2)" "prognostic favorable (9.07e-4)" "unprognostic (4.42e-1)" "prognostic favorable (3.58e-6)" "unprognostic (1.50e-1)" "unprognostic (1.12e-1)" "unprognostic (1.00e-3)" "unprognostic (4.65e-2)" 26.8 38.7 37.0 19.3 49.4 54.9 19.7 13.9 85.6 20.5 0.0 19.6 7.0 19.6 7.4 9.2 19.5 11.0 35.3 42.7 19.9 16.8 30.9 28.4 24.6 48.1 14.2 21.1 19.3 30.9 18.5 19.0 50.6 22.4 7.1 56.3 15.3 13.7 34.4 12.8 22.3 12.3 4.3 46.6 17.7 10.8 17.6 14.0 16.1 27.0 16.4 19.6 15.3 55.1 10.2 13.3 11.4 12.5 9.6 12.8 66.5 10.8 9.1 7.2 5.5 9.1 8.1 21.2 12.0 20.1 7.9 5.8 9.0 5.7 5.3 14.1 19.0 12.6 8.0 38.0 10.3 0.2 5.1 13.0 10.6 14.7 8.3 9.6 6.7 8.6 36.0 20.6 5.1 31.6 8.2 13.1 12.3 7.6 26.4 11.3 3.9 29.6 4.4 12.8 9.5 18.2 7.4 27.5 6.5 10.4 11.6 8.6 17.5 7.5 19.2 6.4 1.5 43.6 64.7 8.1 14.2 6.0 6.1 4.5 2.7 3.9 2.5 2.9 1.9 5.0 1.7 1.9 1.4 4.3 1.7 2.0 8.3 1.3 2.8 4.9 1.3 2.1 37.0 49.4 13.9 85.6 42.7 19.9 48.1 14.2 50.6 4.3 17.6 55.1 29.1 3.2 17.9 59.7 45.6 11.5 7.9 7.8 12.0 110.1 16.1 15.9 183.0 21.5 10.7 3.7 193.9 9.9 48.5 3.4 7.9 6.8 2.9 7.3 13.2 29.8 10.2 46.3 191.3 12.9 42.2 22.8 8.2 5.0 15.2 21.6 24.7 42.7 22.0 235.6 128.4 13.3 4.1 60.4 42.4 4.8 16.8 34.2 7.2 78.7 36.3 16.6 45.3 67.3 78.8 7.8 3.8 22.6 23.3 19.0 3.0 5.8 29.1 123.1 26.3 24.9 30.6 2.2 1.7 3.5 7.7 21.8 24.8 45.2 8.5 13.2 IQSEC2 "BRAG1, IQ-ArfGEF, KIAA0522, MRX1, MRX18, MRX78" ENSG00000124313 "IQ motif and Sec7 domain ArfGEF 2" Q5JU85 X 53225828-53321350 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 58.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 54.0;Late spermatids: 41.6;Proximal enterocytes: 42.1;Proximal tubular cells: 52.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 10.4;plasmacytoid DC: 10.6" "Group enriched" "Detected in many" 16 "dendritic cells: 10.6;monocytes: 10.4" "Cell line enhanced" "Detected in many" "A549: 47.3;GAMG: 58.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003973, HPA076533" Approved "Vesicles,Lipid droplets" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 47: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Lipid droplets" "HPA003973: AB_2280343, HPA076533: " "unprognostic (1.85e-1)" "unprognostic (7.77e-2)" "unprognostic (2.61e-2)" "unprognostic (1.32e-1)" "unprognostic (4.66e-3)" "unprognostic (6.02e-2)" "unprognostic (2.80e-1)" "unprognostic (3.78e-2)" "unprognostic (2.82e-1)" "unprognostic (9.05e-2)" "unprognostic (1.57e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (1.56e-2)" "unprognostic (1.75e-1)" "unprognostic (4.30e-2)" "prognostic favorable (2.38e-4)" 10.8 18.8 18.3 5.8 22.4 2.4 9.9 9.8 32.3 9.7 0.0 14.9 12.5 12.0 4.4 9.5 10.7 6.1 11.2 35.8 0.0 19.4 1.9 8.7 2.8 2.4 0.1 7.6 9.0 14.1 10.9 3.8 2.8 12.0 7.1 3.0 14.9 8.8 58.7 8.9 14.2 7.3 0.3 5.3 10.4 9.9 0.2 3.4 9.7 34.0 3.4 12.1 9.8 14.2 4.8 47.3 1.8 4.4 6.5 13.1 5.3 7.7 13.4 6.2 10.9 1.2 18.2 0.3 12.4 18.3 58.5 6.4 1.7 7.7 4.4 4.8 8.3 5.4 20.8 1.3 14.2 0.2 2.8 9.8 11.8 16.1 9.0 14.4 8.5 0.1 17.3 5.3 12.4 11.2 0.0 1.0 14.6 14.2 21.0 3.5 3.7 6.0 9.0 10.1 1.9 1.8 18.0 11.0 7.5 8.3 15.7 2.3 9.5 5.6 10.6 3.1 3.5 1.5 0.2 0.2 34.6 3.5 3.1 0.1 10.4 0.5 0.0 3.7 0.1 0.2 0.0 0.0 5.4 0.1 0.1 0.0 0.6 0.0 2.0 10.6 0.0 2.3 18.3 22.4 9.8 32.3 35.8 0.0 2.4 0.1 2.8 0.3 0.2 14.2 8.4 6.4 5.9 15.0 1.4 4.0 6.7 11.5 7.4 1.5 12.2 9.5 4.0 12.8 9.3 14.7 0.0 8.0 2.0 21.1 21.5 5.2 18.0 5.4 3.5 6.2 3.6 0.8 54.0 7.1 6.5 6.6 8.2 4.7 3.8 9.1 6.4 0.9 14.7 0.0 25.7 9.7 8.2 12.0 5.0 41.6 1.5 14.1 10.6 17.8 11.9 5.0 0.0 9.5 2.5 5.5 12.6 2.2 1.0 7.0 42.1 52.4 7.6 0.1 0.0 2.7 8.4 0.8 1.5 9.3 3.8 4.5 1.5 2.5 10.7 14.6 IRAK1BP1 "AIP70, SIMPL" ENSG00000146243 "Interleukin 1 receptor associated kinase 1 binding protein 1" Q5VVH5 6 78867551-78946440 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 65.4;Excitatory neurons: 73.1;Inhibitory neurons: 57.2;Late spermatids: 52.0;Oligodendrocyte precursor cells: 56.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 5.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035742, HPA035743" Uncertain Approved Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA035742: AB_10670119, HPA035743: AB_2674764" "unprognostic (2.62e-1)" "unprognostic (1.38e-2)" "unprognostic (1.32e-1)" "unprognostic (1.19e-1)" "unprognostic (5.82e-2)" "unprognostic (2.12e-1)" "unprognostic (2.38e-3)" "unprognostic (3.93e-2)" "unprognostic (6.55e-2)" "unprognostic (2.34e-2)" "unprognostic (1.32e-2)" "unprognostic (9.88e-2)" "unprognostic (2.81e-2)" "unprognostic (4.64e-2)" "unprognostic (1.82e-1)" "unprognostic (3.39e-2)" "unprognostic (2.58e-1)" 1.5 1.8 0.4 1.0 1.0 5.3 2.4 5.3 2.8 1.8 1.7 1.7 1.1 2.8 4.4 1.2 3.2 1.4 1.7 1.0 0.5 2.9 0.9 2.2 1.8 0.3 0.1 3.1 3.2 3.6 3.4 1.1 0.6 1.8 1.4 5.6 2.6 2.4 1.2 2.3 1.4 2.1 0.0 2.0 3.5 3.9 0.5 3.0 3.3 1.1 1.0 1.5 1.5 1.4 1.1 2.0 3.7 3.5 1.6 3.5 2.1 0.8 2.1 0.8 1.4 1.8 0.9 1.6 0.9 1.9 2.0 2.3 7.1 3.4 1.4 3.7 2.8 1.3 2.4 0.9 2.1 7.6 1.3 2.9 3.3 1.5 1.8 2.7 2.7 4.9 4.0 2.1 1.3 0.6 2.2 3.8 1.8 0.5 2.0 0.4 2.2 1.2 3.6 1.9 5.1 6.0 1.1 1.2 0.9 2.4 2.8 5.1 1.9 1.8 1.3 0.6 2.4 2.5 3.3 2.2 0.6 0.3 2.3 0.9 0.0 0.0 0.3 0.0 0.2 0.3 0.3 0.1 0.1 0.2 0.4 0.4 0.4 0.2 0.1 0.4 0.4 0.1 0.4 1.0 5.3 2.8 1.0 0.5 0.3 0.1 0.6 0.0 0.5 1.4 6.1 19.2 7.8 39.2 3.3 2.5 5.3 3.9 10.8 10.3 5.2 8.5 13.6 8.6 9.3 3.7 33.3 3.6 3.5 1.0 9.8 5.5 65.4 20.5 11.5 5.5 6.6 7.8 73.1 6.0 0.8 5.8 5.1 3.6 0.0 11.6 5.0 2.4 1.6 5.0 57.2 2.7 0.0 1.3 0.9 52.0 10.5 1.6 0.0 22.5 0.8 12.9 2.1 56.3 33.6 3.3 1.0 8.2 3.1 1.2 0.6 11.8 21.5 17.9 13.1 8.2 8.1 42.3 15.2 6.3 2.6 0.8 2.5 11.1 3.2 2.8 IRAK2 ENSG00000134070 "Interleukin 1 receptor associated kinase 2" O43187 3 10164919-10243745 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 23.3" "Cell type enhanced" "Detected in many" "Langerhans cells: 43.7;Oligodendrocytes: 34.3;Prostatic glandular cells: 23.4;Urothelial cells: 30.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 33.2;BJ hTERT+: 35.2;CAPAN-2: 35.6;GAMG: 62.6;RT4: 49.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013483, HPA050520" Uncertain Approved Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 41: Macrophages - Immune response" Vesicles "CAB013483: , HPA050520: AB_2681154" "unprognostic (1.31e-1)" "unprognostic (2.04e-2)" "unprognostic (1.46e-2)" "unprognostic (4.61e-3)" "unprognostic (8.71e-2)" "unprognostic (9.55e-2)" "prognostic unfavorable (8.35e-4)" "unprognostic (1.89e-2)" "unprognostic (8.01e-2)" "unprognostic (1.24e-1)" "prognostic unfavorable (2.26e-4)" "unprognostic (2.24e-1)" "unprognostic (3.10e-2)" "unprognostic (7.22e-2)" "unprognostic (4.38e-2)" "unprognostic (3.91e-2)" "prognostic favorable (6.60e-5)" 6.4 3.6 4.0 6.0 3.9 23.3 4.6 3.9 8.0 2.9 1.7 2.1 2.0 2.0 0.7 7.2 1.8 4.4 1.9 3.2 5.1 3.4 10.8 10.4 3.8 5.1 4.1 1.0 1.9 1.0 1.2 2.2 5.6 3.3 1.7 1.5 3.6 1.8 17.0 5.2 5.4 1.4 3.4 4.5 3.4 1.3 4.2 3.9 3.1 4.3 11.5 16.1 4.5 8.0 2.7 7.6 0.3 1.0 8.1 6.7 33.2 2.9 35.2 4.7 4.5 3.6 35.6 0.1 0.9 4.3 62.6 0.8 0.8 9.0 6.3 2.3 2.5 0.8 1.7 9.9 3.9 0.0 1.1 4.1 1.5 17.3 22.4 12.4 9.7 0.3 1.8 10.7 5.7 0.1 0.0 1.8 0.3 4.2 7.5 1.7 0.0 0.6 10.3 49.2 0.5 0.3 3.3 0.1 0.3 0.8 0.8 1.7 10.1 10.7 0.9 6.5 7.0 3.6 11.3 2.1 22.9 4.7 1.9 0.2 1.0 0.1 5.8 0.7 6.0 4.2 1.7 3.3 1.0 3.2 1.2 3.0 2.1 7.4 0.2 0.0 0.7 2.2 4.0 3.9 3.9 8.0 3.2 5.1 5.1 4.1 5.6 3.4 4.2 8.0 3.9 0.0 4.1 1.6 8.3 8.0 20.8 9.9 5.2 0.9 1.6 1.3 2.0 0.0 6.1 0.0 0.0 0.2 3.8 1.3 0.0 9.8 4.1 4.3 2.4 12.3 0.0 0.0 6.3 4.2 0.7 4.3 7.7 16.7 0.0 0.1 0.7 4.8 3.4 0.0 7.0 0.7 4.1 2.9 43.7 1.5 0.9 20.9 5.4 13.1 1.9 2.1 7.2 7.1 34.3 15.7 0.3 0.0 7.4 23.4 2.6 1.1 1.3 0.0 0.0 4.2 2.0 0.7 0.9 4.7 7.4 1.0 3.9 0.2 0.5 30.4 IRAK3 IRAK-M ENSG00000090376 "Interleukin 1 receptor associated kinase 3" Q9Y616 12 66189195-66254622 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.1" "Cell type enhanced" "Detected in many" "Adipocytes: 83.3;Kupffer cells: 123.0;Macrophages: 126.3;Microglial cells: 114.3;monocytes: 96.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 12.7;classical monocyte: 23.4;intermediate monocyte: 24.2;myeloid DC: 11.5;neutrophil: 12.9;non-classical monocyte: 42.0" "Group enriched" "Detected in many" 12 "dendritic cells: 11.5;granulocytes: 12.9;monocytes: 42.0" "Cell line enhanced" "Detected in many" "ASC diff: 25.9;ASC TERT1: 21.1;HEL: 22.9;HL-60: 30.8;NB-4: 25.1;THP-1: 37.3;U-937: 26.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA043097 Approved Approved Vesicles "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA043097: AB_10795612" "unprognostic (7.12e-2)" "unprognostic (1.06e-1)" "unprognostic (2.90e-1)" "unprognostic (1.28e-1)" "unprognostic (1.90e-1)" "unprognostic (7.56e-3)" "unprognostic (1.49e-1)" "unprognostic (2.46e-1)" "unprognostic (7.82e-2)" "unprognostic (1.33e-1)" "unprognostic (2.95e-2)" "unprognostic (8.52e-2)" "prognostic unfavorable (6.23e-4)" "unprognostic (5.58e-2)" "unprognostic (4.64e-2)" "unprognostic (3.41e-2)" "unprognostic (3.23e-2)" 18.7 3.8 3.7 12.4 4.1 78.1 11.6 4.1 7.5 9.3 5.4 4.6 1.3 4.0 3.0 3.8 8.0 6.9 7.9 3.2 4.7 3.5 2.8 19.0 4.1 5.6 5.7 3.2 2.5 0.9 8.9 6.8 6.5 5.3 2.8 0.4 6.2 5.6 2.6 3.4 5.6 5.4 5.0 27.5 6.9 1.8 5.6 2.7 5.0 4.6 3.9 8.4 6.6 5.1 0.0 0.0 0.4 0.0 25.9 21.1 0.0 2.9 0.0 1.5 2.3 0.0 2.2 0.0 1.4 5.3 0.0 0.0 3.2 0.0 1.3 0.0 0.0 22.9 1.4 0.0 13.4 30.8 4.0 13.5 0.1 1.2 0.0 0.0 7.6 0.0 0.0 0.0 1.0 0.0 0.0 25.1 1.3 0.0 0.0 0.0 6.4 0.0 0.1 3.3 0.1 0.0 11.6 0.0 1.2 0.1 0.1 37.3 8.2 0.0 0.0 0.0 0.0 0.9 0.2 2.2 0.0 26.8 0.0 12.7 23.4 4.3 0.0 24.2 0.0 0.1 0.0 0.0 11.5 0.7 0.0 0.0 12.9 1.8 42.0 0.1 0.6 7.3 3.7 4.1 4.1 7.5 3.2 4.7 5.6 5.7 6.5 5.0 5.6 5.1 83.3 9.6 19.4 1.3 2.3 1.5 4.8 27.5 6.2 0.3 2.5 1.8 2.8 0.0 46.9 3.7 0.0 0.2 14.8 0.5 0.0 0.6 6.4 0.5 7.5 38.5 0.0 9.7 0.4 1.2 0.4 22.3 18.3 0.5 27.3 0.5 36.4 1.2 9.4 0.0 5.6 1.1 36.7 123.0 12.1 5.3 7.2 126.3 5.4 114.3 96.9 0.2 3.1 2.0 0.6 4.9 0.1 11.3 9.1 1.6 0.0 0.2 35.1 0.1 0.0 18.1 10.2 0.8 1.8 1.2 1.3 0.3 3.5 12.5 0.7 2.5 IRGQ "FKSG27, IRGQ1" ENSG00000167378 "Immunity related GTPase Q" Q8WZA9 19 43584369-43596135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.3" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043254, HPA050338" Approved Approved Vesicles NA NA 45000 "Cluster 17: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "HPA043254: AB_10794178, HPA050338: AB_2681094" "unprognostic (1.98e-1)" "prognostic favorable (5.17e-4)" "unprognostic (2.55e-1)" "unprognostic (2.07e-3)" "unprognostic (9.87e-2)" "unprognostic (3.20e-3)" "prognostic unfavorable (9.60e-4)" "unprognostic (1.96e-2)" "unprognostic (3.98e-1)" "unprognostic (7.48e-2)" "prognostic favorable (3.57e-5)" "unprognostic (9.24e-2)" "prognostic favorable (3.92e-4)" "unprognostic (2.82e-1)" "unprognostic (7.91e-2)" "unprognostic (5.18e-2)" "unprognostic (4.65e-2)" 2.3 3.0 6.7 1.5 6.6 7.0 2.4 2.3 8.3 3.6 0.0 2.9 1.5 3.4 1.5 2.8 3.3 1.2 4.5 8.0 4.5 2.5 2.4 3.7 1.0 12.7 5.6 4.3 2.7 2.2 4.2 1.4 5.2 2.8 1.3 3.2 3.1 1.6 6.0 2.9 2.0 1.6 1.5 2.3 2.7 2.2 7.4 1.0 2.6 3.9 1.5 2.7 2.9 3.6 2.6 4.3 3.5 7.1 3.7 2.6 3.5 2.3 1.4 2.6 2.6 3.3 1.5 1.6 3.6 2.8 2.5 3.7 3.3 1.8 1.6 3.1 2.4 2.3 6.0 2.7 2.3 3.1 3.2 2.6 3.6 3.3 1.8 2.8 3.3 2.7 3.4 3.3 2.5 2.2 3.9 2.2 1.8 0.8 2.3 7.2 3.2 1.3 2.1 5.4 6.7 6.0 6.3 6.4 1.8 3.7 4.2 2.8 5.2 8.7 6.3 2.2 3.2 3.4 3.1 2.8 5.2 1.4 7.0 2.3 0.5 0.3 0.2 0.4 0.2 0.2 0.2 0.2 0.3 0.3 0.3 0.2 1.0 0.3 0.5 0.5 0.2 0.3 6.7 6.6 2.3 8.3 8.0 4.5 12.7 5.6 5.2 1.5 7.4 3.6 5.3 12.8 18.1 9.8 5.4 6.5 10.9 8.8 8.6 17.1 16.5 11.0 28.8 17.2 10.5 3.7 27.1 5.8 5.0 15.7 1.9 12.6 7.4 12.6 14.5 10.9 36.0 4.4 11.7 13.0 3.8 8.0 9.7 18.6 12.7 18.3 8.2 14.3 8.6 20.2 12.3 14.4 2.0 11.1 9.9 5.7 3.1 12.0 5.4 4.7 7.2 11.9 0.0 9.0 9.1 17.8 8.6 10.5 5.9 18.5 10.5 10.9 7.0 20.8 0.0 13.8 9.3 2.8 2.6 12.5 6.7 7.7 5.3 9.6 11.8 16.4 IRX4 ENSG00000113430 "Iroquois homeobox 4" P78413 5 1877413-1887236 "Plasma proteins, Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 15.8;heart muscle: 14.3;skin 1: 22.5;vagina: 12.2" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 48.6;Basal squamous epithelial cells: 50.7;Breast myoepithelial cells: 15.6;Prostatic glandular cells: 13.3;Squamous epithelial cells: 26.5;Suprabasal keratinocytes: 20.2" "Group enriched" "Detected in many" 5 "cervical cancer: 5.4;head and neck cancer: 7.3;lung cancer: 1.8;prostate cancer: 6.9;testis cancer: 7.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 41.8;HaCaT: 16.3;HBEC3-KT: 8.1;MCF7: 8.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "medulla oblongata: 1.2;pons: 1.5" HPA064094 Uncertain Nucleoplasm,Vesicles NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Vesicles" "HPA064094: " "unprognostic (1.00e-2)" "unprognostic (1.00e-1)" "unprognostic (1.90e-1)" "unprognostic (3.01e-1)" "unprognostic (1.35e-2)" "unprognostic (2.77e-1)" "unprognostic (1.53e-1)" "unprognostic (1.35e-1)" "unprognostic (7.52e-2)" "unprognostic (7.54e-2)" "unprognostic (4.26e-1)" "unprognostic (1.70e-2)" 0.2 0.0 0.0 0.0 0.0 0.1 3.2 0.7 0.0 3.7 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 14.3 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.7 0.0 0.0 0.0 0.9 0.0 1.2 9.9 0.0 0.0 9.5 0.0 0.6 22.5 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 12.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 41.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 16.3 0.0 8.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 8.3 1.1 0.1 0.1 4.3 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.3 2.1 0.0 0.0 0.0 3.4 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.8 0.7 1.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 48.6 2.8 0.1 50.7 0.0 1.4 15.6 6.7 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.0 0.3 0.0 0.2 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 1.1 26.5 20.2 3.7 0.0 0.0 0.0 1.7 ISOC1 CGI-111 ENSG00000066583 "Isochorismatase domain containing 1" Q96CN7 5 129094749-129114028 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SH-SY5Y: 156.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070307 Approved "Endoplasmic reticulum,Vesicles" NA NA 1900000 "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 39: Non-specific - Basic cellular processes" "Endoplasmic reticulum, Vesicles" "HPA070307: AB_2686249" "unprognostic (1.67e-1)" "unprognostic (4.46e-2)" "unprognostic (1.29e-1)" "unprognostic (6.42e-3)" "unprognostic (3.87e-2)" "unprognostic (1.91e-1)" "unprognostic (6.32e-2)" "unprognostic (1.90e-1)" "unprognostic (2.47e-1)" "unprognostic (4.19e-2)" "unprognostic (2.00e-2)" "unprognostic (4.18e-1)" "unprognostic (7.09e-3)" "unprognostic (2.49e-1)" "unprognostic (2.65e-1)" "unprognostic (1.65e-2)" "unprognostic (1.32e-2)" 27.8 28.0 11.9 12.8 12.2 12.6 25.5 11.9 13.7 57.2 11.4 19.6 32.1 102.7 21.0 22.1 27.2 15.6 65.7 11.1 16.0 33.6 100.2 14.0 14.6 15.9 16.4 17.1 19.9 15.7 20.5 15.3 13.8 19.7 21.7 14.8 28.4 8.9 17.1 23.5 28.3 64.9 13.8 10.0 20.4 11.1 15.2 18.9 13.3 16.4 16.8 21.3 19.2 15.2 27.7 21.4 21.7 33.5 35.0 18.5 95.7 11.7 10.0 13.1 23.1 75.5 38.2 19.6 28.3 6.9 40.0 14.7 46.5 35.2 24.2 107.5 52.8 39.0 20.9 55.7 24.7 15.6 13.6 12.2 10.5 20.5 17.7 9.4 31.6 30.6 43.0 33.2 11.6 110.2 29.2 25.3 33.5 26.4 57.8 41.5 63.2 19.3 32.9 55.4 36.6 156.9 33.7 42.3 21.6 19.7 34.9 13.0 13.4 14.8 28.1 11.9 38.3 27.5 22.9 32.7 16.5 48.4 17.0 64.0 25.2 38.0 54.0 25.0 61.4 47.7 50.3 57.7 31.5 49.4 43.9 51.8 30.9 61.4 25.3 29.0 69.0 48.9 11.9 12.2 11.9 13.7 11.1 16.0 15.9 16.4 13.8 13.8 15.2 15.2 58.1 12.8 17.2 6.5 18.9 131.8 42.4 28.5 88.2 12.4 33.6 19.8 70.6 34.3 19.3 20.2 10.4 74.7 26.3 19.9 125.2 22.2 1.6 23.5 30.1 16.9 31.8 21.0 1.7 28.1 71.8 33.9 17.3 24.9 18.4 51.0 5.3 84.7 23.9 0.0 5.6 26.6 30.5 8.8 41.0 4.2 13.7 14.3 28.4 4.7 18.9 52.9 18.6 6.0 9.2 16.3 29.8 19.2 36.9 38.5 45.7 96.2 10.6 6.5 0.0 33.7 15.9 6.5 38.1 53.7 84.1 50.9 26.4 79.3 32.8 37.8 IST1 "CHMP8, KIAA0174" ENSG00000182149 "IST1 factor associated with ESCRT-III" P53990 16 71845996-71931199 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041802, HPA054532" Approved Supported Vesicles NA NA 270000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA041802: AB_10794491, HPA054532: AB_2682517" "unprognostic (2.15e-1)" "unprognostic (2.80e-1)" "unprognostic (1.22e-1)" "unprognostic (1.67e-3)" "unprognostic (2.04e-2)" "unprognostic (3.13e-3)" "unprognostic (2.11e-2)" "unprognostic (4.49e-2)" "unprognostic (3.96e-2)" "unprognostic (1.32e-1)" "unprognostic (1.31e-1)" "unprognostic (1.02e-1)" "prognostic favorable (4.55e-4)" "unprognostic (1.64e-2)" "unprognostic (7.88e-3)" "unprognostic (8.43e-3)" "prognostic favorable (8.88e-4)" 47.7 44.1 43.2 38.8 49.7 81.0 50.5 46.2 50.6 49.0 43.9 68.3 52.4 55.9 42.4 50.5 61.4 46.8 50.4 42.9 45.3 68.7 37.9 50.0 64.3 47.2 47.6 60.0 46.9 90.4 57.2 60.1 47.1 45.7 62.9 32.4 52.0 45.8 64.1 52.5 52.0 60.8 45.5 50.6 52.5 47.4 46.1 62.2 59.4 80.8 81.6 53.0 44.3 53.8 57.0 81.9 113.3 73.2 110.7 77.9 95.7 70.0 87.1 95.2 98.9 90.1 77.1 80.5 84.2 81.2 67.7 83.8 112.0 74.2 120.4 53.7 54.1 68.1 46.8 146.9 83.8 66.9 91.9 92.7 100.8 85.5 81.6 94.8 120.6 74.8 94.5 28.7 99.5 94.9 87.4 55.6 129.7 92.7 50.6 135.7 62.0 99.1 78.5 81.8 85.0 63.3 77.2 40.3 63.9 138.2 73.7 82.2 60.7 71.8 70.9 44.5 55.9 75.0 145.5 226.7 60.7 59.2 88.6 234.9 195.1 243.5 158.7 185.4 172.6 179.1 150.6 166.9 180.1 178.5 159.6 150.1 300.0 193.7 185.1 124.9 244.9 293.9 43.2 49.7 46.2 50.6 42.9 45.3 47.2 47.6 47.1 45.5 46.1 53.8 59.7 48.1 51.8 39.8 57.1 70.1 41.2 49.8 39.9 29.2 69.1 50.0 43.9 60.1 48.1 46.0 25.0 56.7 68.4 130.6 35.2 47.1 18.4 50.0 52.8 55.4 75.4 30.7 35.5 41.7 44.3 48.1 42.3 70.1 61.4 55.1 61.1 40.8 53.4 21.9 41.6 76.3 46.8 81.1 73.8 22.5 41.0 57.2 42.7 38.4 75.9 22.2 51.5 34.2 59.7 58.1 88.4 47.8 45.2 51.5 82.2 52.4 56.2 30.3 59.2 45.3 44.4 52.4 57.3 34.4 70.0 65.7 51.8 31.3 57.6 66.4 ITCH AIP4 ENSG00000078747 "Itchy E3 ubiquitin protein ligase" Q96J02 20 34363241-34540748 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 139.7;Oligodendrocytes: 260.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021126, HPA049032, CAB072824, CAB072825" Supported Enhanced Nucleoplasm,Vesicles No No "Cluster 1: Neutrophils - Mixed function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm Vesicles "CAB072824: , CAB072825: , HPA021126: AB_1851941, HPA049032: AB_2680607" "unprognostic (2.51e-1)" "unprognostic (6.95e-2)" "unprognostic (1.25e-3)" "unprognostic (3.22e-2)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (2.78e-1)" "unprognostic (9.29e-3)" "unprognostic (1.94e-1)" "unprognostic (3.89e-3)" "unprognostic (1.28e-3)" "unprognostic (1.42e-1)" "unprognostic (1.84e-2)" "unprognostic (1.30e-1)" "unprognostic (2.24e-1)" "unprognostic (3.23e-2)" "unprognostic (2.21e-1)" 19.5 16.2 13.7 18.1 27.1 27.3 20.0 19.6 17.7 24.5 17.7 21.6 20.2 19.4 16.6 42.8 15.7 17.0 20.2 14.7 15.9 23.3 55.6 18.7 21.4 19.8 20.0 18.8 16.5 23.1 7.8 25.6 21.0 19.6 23.5 25.6 18.7 19.9 17.2 14.0 20.9 21.5 15.9 20.4 20.9 38.5 20.2 23.2 26.3 21.7 25.7 30.6 14.8 45.7 55.5 34.6 35.2 25.9 38.3 57.4 42.7 43.5 52.0 56.2 54.0 101.5 83.8 26.7 42.1 55.6 73.9 66.2 54.9 92.3 66.2 20.8 17.9 78.3 28.2 59.3 43.9 32.6 34.4 31.7 46.2 44.4 72.2 49.8 41.7 40.6 45.5 45.7 46.2 26.5 49.2 18.8 16.9 35.6 44.2 40.9 76.3 63.6 34.7 91.2 21.4 16.4 82.0 32.7 51.0 33.9 38.3 31.1 39.5 61.5 36.0 42.8 33.3 36.2 40.5 40.0 41.0 21.6 38.0 4.6 6.7 7.0 12.0 7.0 12.5 9.2 4.2 6.1 4.9 7.8 3.7 5.7 20.2 7.6 4.9 14.3 5.8 4.3 13.7 27.1 19.6 17.7 14.7 15.9 19.8 20.0 21.0 15.9 20.2 45.7 26.1 12.8 21.8 56.5 33.1 15.0 23.9 11.7 25.6 19.5 15.1 8.5 25.0 12.8 25.6 31.3 25.0 17.5 46.1 28.8 5.9 12.8 59.0 26.5 34.6 20.7 12.0 26.5 85.0 16.3 21.2 24.2 33.1 36.1 19.0 17.9 18.2 53.0 15.8 15.2 72.3 16.9 10.2 24.3 26.7 139.7 22.4 31.4 26.6 68.4 30.0 38.2 43.3 79.4 260.0 22.6 23.7 15.4 50.3 25.8 21.1 26.8 23.5 26.0 13.1 21.4 22.0 40.6 25.5 30.4 16.2 46.9 30.8 12.3 11.9 40.6 ITGA7 ENSG00000135424 "Integrin subunit alpha 7" Q13683 12 55684568-55716043 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Cell shape" "Integrin, Receptor" "Congenital muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 262.3" "Group enriched" "Detected in many" 6 "Astrocytes: 87.5;Cardiomyocytes: 124.5;Sertoli cells: 164.3;Skeletal myocytes: 65.8;Smooth muscle cells: 110.6" "Cancer enhanced" "Detected in all" "glioma: 35.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "hTERT-RPE1: 309.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008427 Uncertain Approved "Nuclear speckles,Vesicles,Plasma membrane" NA NA 1200000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Nuclear speckles, Vesicles" "HPA008427: AB_1851823" "unprognostic (4.71e-2)" "unprognostic (1.55e-1)" "unprognostic (2.00e-3)" "unprognostic (3.02e-3)" "unprognostic (2.50e-1)" "unprognostic (2.36e-1)" "unprognostic (1.66e-2)" "unprognostic (2.20e-1)" "unprognostic (2.20e-2)" "unprognostic (3.57e-1)" "prognostic favorable (1.75e-4)" "unprognostic (2.85e-2)" "unprognostic (5.89e-2)" "unprognostic (1.79e-1)" "unprognostic (5.10e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (9.59e-5)" 133.4 8.2 18.5 18.5 21.2 1.8 69.0 15.9 30.2 28.7 16.1 97.8 17.7 45.5 12.3 23.9 56.1 30.8 157.9 34.5 17.8 11.5 10.2 15.5 6.4 21.2 21.1 19.1 5.1 6.1 12.6 1.9 20.3 33.9 8.9 2.4 14.9 37.3 262.3 16.0 27.4 95.2 16.4 10.2 35.2 8.9 23.8 3.4 26.1 154.1 3.3 46.5 25.5 21.0 0.2 4.1 7.5 12.3 66.5 13.4 0.7 5.4 8.7 11.7 11.8 8.4 6.5 2.3 7.4 3.4 0.9 1.1 5.1 0.3 10.0 0.2 3.8 0.8 2.8 3.2 0.5 0.3 2.7 19.1 0.2 64.2 0.3 309.1 0.2 2.2 0.9 1.6 37.8 5.3 0.3 3.1 20.9 1.7 0.4 0.1 28.7 0.6 0.2 0.2 0.9 2.8 0.6 0.2 48.0 4.0 0.9 13.9 0.0 1.3 12.4 0.8 8.4 3.2 2.2 0.9 57.8 8.2 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 18.5 21.2 15.9 30.2 34.5 17.8 21.2 21.1 20.3 16.4 23.8 21.0 11.9 0.0 0.0 87.5 0.3 1.9 0.5 0.1 0.6 2.4 1.2 3.4 124.5 2.8 0.0 1.8 4.2 0.0 0.3 0.7 0.0 0.3 0.3 1.1 1.2 9.5 7.7 0.4 17.6 0.0 0.1 5.0 0.5 1.1 0.0 6.2 0.7 1.4 0.6 0.0 9.4 1.8 0.0 1.9 2.7 0.1 6.5 2.2 3.6 9.4 0.0 3.4 0.0 6.6 3.7 0.3 0.1 6.4 0.1 0.8 2.6 0.8 0.1 0.6 164.3 65.8 110.6 4.1 2.9 0.7 2.3 0.1 0.5 0.3 0.9 0.3 ITGA9 "ALPHA-RLC, ITGA4L, RLC" ENSG00000144668 "Integrin subunit alpha 9" Q13797 3 37452115-37823507 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 82.0;Hepatic stellate cells: 54.3;Inhibitory neurons: 61.0;Leydig cells: 41.3;Microglial cells: 53.4;Oligodendrocyte precursor cells: 93.5;Peritubular cells: 74.9" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 23.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 10.1;HEL: 8.1;SH-SY5Y: 11.8;SuSa: 16.9;WM-115: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030609 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 500000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Nucleoplasm, Plasma membrane, Cell Junctions" "HPA030609: AB_10600815" "unprognostic (2.35e-2)" "unprognostic (3.36e-2)" "unprognostic (5.58e-2)" "unprognostic (3.94e-2)" "unprognostic (4.48e-2)" "unprognostic (2.85e-2)" "unprognostic (3.10e-1)" "unprognostic (8.87e-3)" "unprognostic (3.23e-1)" "unprognostic (2.31e-1)" "unprognostic (2.04e-1)" "unprognostic (1.51e-1)" "unprognostic (1.78e-2)" "unprognostic (1.50e-2)" "unprognostic (1.07e-1)" "unprognostic (1.72e-2)" "unprognostic (3.16e-2)" 8.8 15.5 1.9 4.5 1.8 8.5 5.9 0.0 6.2 21.8 3.6 9.6 6.3 10.6 4.0 15.5 5.4 9.4 20.1 7.8 0.7 4.0 14.8 8.9 4.1 0.9 1.3 5.0 1.8 2.6 1.7 9.8 0.4 12.5 6.8 0.7 4.2 10.8 2.8 3.0 9.1 15.8 0.7 22.6 7.5 6.9 5.0 1.8 20.7 9.8 2.4 6.5 4.5 1.2 0.2 0.0 4.3 0.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 10.1 0.0 3.2 1.4 0.0 0.1 0.2 3.8 0.0 0.0 0.1 0.6 8.1 0.1 0.2 0.2 0.0 4.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.4 0.3 0.0 0.2 0.5 11.8 0.1 0.5 0.7 16.9 0.0 3.1 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.2 6.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.8 0.0 6.2 7.8 0.7 0.9 1.3 0.4 0.7 5.0 1.2 20.8 0.0 14.7 16.0 0.1 2.5 1.1 0.1 1.2 1.2 1.1 2.9 12.9 2.8 3.1 1.8 0.0 0.2 0.0 0.0 0.0 0.1 1.5 1.4 4.9 21.6 0.0 3.0 82.0 0.0 0.5 7.5 0.0 0.9 6.3 36.2 54.3 1.3 2.8 0.0 61.0 0.1 0.0 31.9 2.2 4.2 41.3 5.7 3.6 53.4 0.1 0.6 0.0 93.5 6.2 0.0 0.0 74.9 0.4 0.2 0.0 0.1 0.0 0.0 0.0 3.2 3.3 0.6 0.9 0.0 1.7 0.3 1.8 25.9 0.4 0.3 ITIH1 "H1P, IATIH, ITIH" ENSG00000055957 "Inter-alpha-trypsin inhibitor heavy chain 1" P19827 3 52777595-52792068 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 782 "liver: 1504.9" "Cell type enriched" "Detected in some" 34 "Hepatocytes: 1087.0" "Cancer enriched" "Detected in some" 598 "liver cancer: 329.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 5.3;Hep G2: 1.7;HL-60: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041639, HPA042049" Approved Approved Vesicles "Secreted to blood" NA NA 4490000 59000000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA041639: AB_10796349, HPA042049: AB_10797379" "unprognostic (1.87e-4)" "unprognostic (1.31e-3)" "unprognostic (2.38e-1)" "unprognostic (8.55e-2)" "unprognostic (1.03e-1)" "unprognostic (2.64e-3)" "prognostic favorable (1.89e-5)" "unprognostic (2.27e-2)" "unprognostic (1.70e-1)" "unprognostic (1.30e-1)" "unprognostic (2.91e-2)" "unprognostic (8.45e-2)" "unprognostic (4.53e-4)" "unprognostic (4.02e-3)" "unprognostic (5.70e-3)" "unprognostic (2.08e-1)" "unprognostic (2.24e-2)" 0.8 0.3 0.0 0.5 0.0 0.0 0.3 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.4 0.0 0.0 0.2 1504.9 0.1 0.5 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.1 0.0 0.0 1.9 0.4 0.4 0.0 0.4 0.0 0.1 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 31.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.1 0.0 29.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 18.5 1087.0 0.1 0.0 0.0 0.0 0.0 20.2 0.0 1.7 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.1 ITIH4 "H4P, IHRP, ITIHL1" ENSG00000055955 "Inter-alpha-trypsin inhibitor heavy chain 4" Q14624 3 52812962-52830688 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 38 "liver: 1863.4" "Group enriched" "Detected in many" 5 "Early spermatids: 119.2;Hepatocytes: 134.6;Late spermatids: 126.5" "Cancer enriched" "Detected in single" 27 "liver cancer: 7.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 2.4;JURKAT: 2.0;U-266/70: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA001835, HPA003948, CAB072872" Enhanced Approved Vesicles "Secreted to blood" NA NA 3060000 58000000000 "Cluster 15: NK-cells - Transcription" "Cluster 62: Liver - Hemostasis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB072872: AB_2665724, HPA001835: AB_1079432, HPA003948: AB_1079433" "unprognostic (6.08e-2)" "unprognostic (4.45e-2)" "unprognostic (1.67e-1)" "unprognostic (2.69e-1)" "unprognostic (2.64e-1)" "unprognostic (1.96e-1)" "unprognostic (5.86e-2)" "unprognostic (1.98e-2)" "unprognostic (5.64e-2)" "unprognostic (1.02e-1)" "unprognostic (2.47e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-14)" "unprognostic (1.71e-3)" "unprognostic (2.96e-2)" "unprognostic (1.52e-1)" "unprognostic (4.21e-5)" 4.2 18.5 4.1 1.2 4.2 10.0 3.0 3.7 5.0 4.2 3.5 3.6 1.0 2.9 1.7 1.4 3.8 1.1 3.2 3.9 3.6 5.4 1863.4 4.9 1.7 3.9 3.8 2.4 48.9 0.1 4.3 0.7 3.9 4.0 1.0 3.3 2.1 1.8 40.3 2.5 3.4 1.5 3.6 7.4 3.9 1.8 3.8 2.2 5.2 2.8 1.2 5.3 3.3 3.9 0.0 0.1 0.4 0.9 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.2 0.1 0.4 0.0 0.0 0.2 2.4 0.1 1.0 0.0 1.2 0.4 1.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 2.0 0.3 0.8 0.0 0.1 0.2 0.3 0.4 0.1 0.0 0.8 0.3 0.0 0.2 0.3 0.0 0.4 0.3 0.0 0.1 0.4 0.5 0.3 0.1 0.0 0.4 0.4 0.0 3.0 1.4 0.2 0.0 0.3 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 4.1 4.2 3.7 5.0 3.9 3.6 3.9 3.8 3.9 3.6 3.8 3.9 0.7 0.0 1.1 22.5 0.9 0.8 0.3 0.3 0.0 10.0 0.6 1.3 1.1 2.8 0.8 0.0 12.5 0.0 0.4 0.1 0.0 0.3 119.2 0.7 0.7 0.8 0.0 8.4 11.6 2.6 0.0 0.6 1.1 0.4 0.0 2.7 2.5 134.6 0.5 5.0 8.6 0.2 0.0 2.2 1.0 126.5 1.2 1.3 0.0 5.6 1.9 2.3 2.1 3.0 3.1 2.3 0.5 1.9 0.7 0.2 0.0 0.3 0.3 6.0 6.6 6.2 2.4 1.3 1.5 0.0 0.3 0.3 1.2 3.2 0.1 0.1 ITIH5 MGC10848 ENSG00000123243 "Inter-alpha-trypsin inhibitor heavy chain 5" 10 7559270-7666998 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 112.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 282.7;Fibroblasts: 111.3;Microglial cells: 160.2;Smooth muscle cells: 110.1;Syncytiotrophoblasts: 221.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "WM-115: 102.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038305 Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus" Vesicles "HPA038305: AB_10670662" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "unprognostic (3.11e-3)" "unprognostic (6.80e-2)" "unprognostic (1.80e-1)" "unprognostic (5.84e-3)" "unprognostic (1.63e-1)" "unprognostic (2.55e-2)" "unprognostic (1.53e-1)" "unprognostic (2.90e-1)" "unprognostic (5.80e-3)" "unprognostic (6.11e-2)" "unprognostic (1.36e-1)" "unprognostic (6.79e-3)" "unprognostic (2.00e-2)" "unprognostic (4.50e-2)" "unprognostic (3.48e-2)" 112.7 3.7 17.9 19.4 18.6 0.2 53.3 19.7 23.2 17.4 28.6 62.7 13.9 24.3 6.3 21.4 10.5 27.7 16.8 14.7 18.0 16.4 1.6 22.4 12.5 18.9 18.1 21.2 15.0 6.3 5.4 86.9 19.7 24.0 16.8 3.5 9.5 46.6 17.8 12.0 21.6 28.8 15.7 3.4 24.0 6.2 22.5 3.8 24.5 22.5 13.4 51.4 15.3 15.2 0.0 0.0 0.0 0.1 0.0 0.0 7.0 18.0 0.0 0.0 0.0 0.0 0.1 0.0 3.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 5.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.7 0.0 0.0 0.0 12.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.5 14.8 0.0 0.0 0.0 0.0 1.6 0.1 0.0 0.2 0.1 0.0 0.0 0.0 102.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.9 18.6 19.7 23.2 14.7 18.0 18.9 18.1 19.7 15.7 22.5 15.2 74.9 3.2 2.7 1.3 0.2 11.3 3.0 0.1 6.8 2.7 1.6 17.3 8.7 8.6 3.7 0.0 2.1 282.7 0.8 0.1 0.0 25.7 2.0 18.7 1.5 58.8 0.0 0.0 0.5 0.4 70.2 111.3 0.0 34.1 2.5 0.5 1.8 0.1 20.7 0.0 0.7 0.0 8.2 1.2 19.6 2.2 5.3 3.6 14.2 160.2 1.1 21.9 0.0 1.5 1.0 0.3 0.0 15.4 0.9 1.8 0.2 2.1 0.7 3.2 78.9 32.3 110.1 1.7 7.7 0.7 8.8 221.9 3.0 0.3 0.0 1.6 ITM2A "BRICD2A, E25A" ENSG00000078596 "Integral membrane protein 2A" O43736 X 79360384-79367667 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 322.9" "Cell type enhanced" "Detected in many" "Adipocytes: 390.0;Endothelial cells: 368.4;Fibroblasts: 302.1;granulocytes: 194.6;Leydig cells: 335.5;Muller glia cells: 188.9;T-cells: 239.2" "Cancer enhanced" "Detected in all" "glioma: 51.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 172.6;eosinophil: 88.5;gdT-cell: 107.1;MAIT T-cell: 79.3;memory CD4 T-cell: 204.7;memory CD8 T-cell: 170.5;naive CD4 T-cell: 216.7;naive CD8 T-cell: 101.6;NK-cell: 130.3;T-reg: 168.1" "Group enriched" "Detected in all" 7 "granulocytes: 172.6;NK-cells: 130.3;T-cells: 216.7" "Cell line enriched" "Detected in some" 5 "MOLT-4: 1749.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000296 Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Golgi apparatus, Plasma membrane" "HPA000296: " "unprognostic (1.05e-2)" "unprognostic (5.22e-3)" "unprognostic (2.77e-3)" "unprognostic (5.65e-2)" "unprognostic (1.73e-2)" "unprognostic (1.06e-3)" "prognostic favorable (3.66e-6)" "unprognostic (1.57e-1)" "unprognostic (4.94e-2)" "unprognostic (9.85e-2)" "unprognostic (1.33e-2)" "unprognostic (2.57e-1)" "unprognostic (1.04e-2)" "unprognostic (1.56e-1)" "unprognostic (3.31e-1)" "unprognostic (2.18e-1)" "unprognostic (4.30e-1)" 80.2 10.8 103.4 26.8 95.2 45.8 74.5 99.4 172.0 55.3 75.5 30.5 15.1 44.4 18.8 40.1 42.8 28.8 115.3 92.1 105.4 20.6 6.3 52.2 87.2 101.5 102.2 181.4 10.0 14.9 21.0 29.7 102.0 22.8 32.2 11.9 74.9 22.4 41.2 25.0 22.1 56.6 95.2 24.5 24.2 15.9 109.8 322.9 83.1 75.2 46.9 42.3 26.0 95.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 216.6 2.5 0.0 4.4 0.0 69.9 0.0 0.0 0.0 113.1 124.2 19.5 0.0 0.0 0.0 0.1 0.0 333.3 80.2 0.0 0.0 0.0 1749.0 77.6 25.0 0.0 0.0 0.7 0.1 0.3 64.6 0.0 0.2 19.0 0.0 0.9 0.0 17.6 2.2 2.5 3.0 0.0 1.8 0.4 1.1 208.1 0.0 0.0 0.2 0.0 8.7 172.6 0.8 88.5 107.1 1.3 79.3 23.4 204.7 170.5 0.8 23.5 216.7 101.6 3.9 130.3 1.1 6.1 168.1 115.3 103.4 95.2 99.4 172.0 92.1 105.4 101.5 102.2 102.0 95.2 109.8 95.8 390.0 3.2 14.8 1.0 28.0 67.4 13.2 2.1 50.1 3.1 21.1 81.9 29.3 2.8 4.4 1.8 0.0 0.4 64.8 2.1 5.9 0.4 3.1 0.4 2.6 368.4 2.4 42.7 3.5 50.9 0.2 302.1 29.6 0.6 194.6 1.4 135.0 1.0 1.3 1.7 2.3 85.6 0.0 9.5 39.5 7.1 335.5 8.6 62.2 114.3 3.2 188.9 65.9 18.1 60.2 1.0 1.4 117.8 81.8 12.3 0.2 1.4 0.7 12.1 0.0 31.8 22.5 0.5 2.6 24.3 47.0 0.3 239.2 2.0 2.9 2.5 ITM2B "BRI, BRI2, BRICD2B, E25B, E3-16" ENSG00000136156 "Integral membrane protein 2B" Q9Y287 13 48232612-48270357 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Amyloidosis, Deafness, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 4375.2" "Lineage enriched" "Detected in all" 5 "granulocytes: 4375.2" "Cell line enhanced" "Detected in all" "HMC-1: 731.2;RPTEC TERT1: 1718.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029292, HPA071992" Enhanced Enhanced "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 5800000 "Cluster 5: Granulocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus, Vesicles" "HPA029292: AB_10601917, HPA071992: AB_2686480" "unprognostic (4.66e-2)" "unprognostic (2.02e-1)" "unprognostic (1.03e-2)" "unprognostic (1.00e-1)" "unprognostic (4.41e-2)" "unprognostic (6.84e-2)" "unprognostic (2.52e-1)" "unprognostic (1.29e-1)" "unprognostic (9.88e-2)" "unprognostic (2.42e-1)" "unprognostic (5.89e-2)" "unprognostic (2.87e-2)" "prognostic favorable (3.73e-5)" "unprognostic (4.38e-2)" "unprognostic (4.09e-2)" "unprognostic (6.00e-2)" "unprognostic (1.22e-1)" 510.2 367.4 286.9 172.5 301.0 125.6 323.8 328.6 489.0 416.1 406.6 260.1 289.2 388.8 1171.8 399.9 305.4 257.5 381.0 320.1 339.2 1306.3 391.2 376.1 236.7 334.9 308.0 507.2 179.6 233.7 290.5 573.8 304.4 312.5 191.4 174.4 408.7 386.2 164.7 399.6 287.4 232.5 373.6 435.2 312.8 121.4 308.8 188.3 386.1 206.2 187.4 305.1 402.2 394.8 67.6 51.8 73.1 116.3 348.5 254.5 119.2 215.0 202.2 87.5 100.6 29.1 248.3 16.6 168.8 121.6 48.5 214.1 61.3 107.0 107.4 69.9 147.3 137.9 29.0 99.0 138.5 140.6 731.2 113.4 149.1 45.1 62.0 375.7 131.2 78.3 24.5 90.9 174.8 29.6 200.4 310.1 266.0 116.5 103.6 100.1 100.5 73.6 1718.9 268.6 26.2 119.5 154.5 110.2 111.0 306.0 74.0 119.4 180.5 62.9 73.8 95.7 85.4 72.9 59.6 2.5 78.0 75.3 155.3 3091.4 864.5 2737.9 387.4 661.3 512.5 235.3 523.1 476.4 428.9 245.3 551.3 466.8 4375.2 356.5 692.7 196.2 563.4 1723.5 286.9 301.0 328.6 489.0 320.1 339.2 334.9 308.0 304.4 373.6 308.8 394.8 1380.0 695.5 300.4 174.6 408.6 862.4 1661.1 2606.2 1006.2 653.1 460.1 573.5 384.8 722.0 1121.9 1991.8 187.7 1164.3 448.2 754.2 545.9 910.2 23.6 751.8 802.2 1166.2 283.3 307.0 114.2 682.9 2362.8 1334.0 302.8 1177.2 578.0 421.2 1319.7 557.3 2117.8 353.3 142.6 503.2 1129.1 1569.8 900.6 76.7 1867.0 1381.5 681.3 252.0 1415.7 1634.9 425.3 174.4 237.9 515.7 788.3 2011.6 445.4 922.5 1259.3 2748.9 795.6 219.4 1222.7 602.4 1022.9 143.6 256.4 1384.6 1149.6 1471.5 723.2 665.5 440.9 1613.4 ITPKA "IP3-3KA, IP3KA" ENSG00000137825 "Inositol-trisphosphate 3-kinase A" P23677 15 41493393-41503551 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.5;intestine: 18.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 51.4;Early spermatids: 45.4;Gastric mucus-secreting cells: 34.1;Late spermatids: 166.4;Proximal enterocytes: 35.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "MAIT T-cell: 1.4" "Lineage enriched" "Detected in single" 11 "T-cells: 1.4" "Cell line enhanced" "Detected in many" "Hep G2: 33.6;OE19: 18.2" "Low region specificity" "Detected in all" HPA040454 Enhanced Approved Approved "Vesicles,Plasma membrane" No No "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "Plasma membrane" "HPA040454: AB_10672897" "unprognostic (5.91e-2)" "unprognostic (2.16e-3)" "unprognostic (4.19e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (6.77e-4)" "unprognostic (2.25e-2)" "unprognostic (2.69e-2)" "unprognostic (1.01e-1)" "unprognostic (3.58e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (3.76e-9)" "unprognostic (2.15e-1)" "unprognostic (2.87e-1)" "unprognostic (1.12e-3)" "unprognostic (2.10e-2)" 0.2 7.3 21.4 0.7 26.7 0.4 0.2 13.8 36.5 1.3 10.9 10.7 17.6 0.3 0.1 0.3 0.5 0.2 2.6 28.7 12.4 0.2 1.7 0.5 0.1 10.9 12.0 0.3 1.9 2.0 0.4 0.3 11.6 0.8 2.7 0.3 1.4 0.3 4.4 0.4 18.1 0.3 11.3 0.2 10.9 10.4 12.1 0.0 0.2 0.0 0.0 0.6 0.9 20.4 7.1 1.9 0.3 7.9 0.0 2.5 14.3 4.3 3.4 2.8 2.9 16.3 0.3 0.0 3.5 0.4 6.3 0.8 3.4 0.3 0.2 6.6 4.3 9.9 4.7 33.6 12.6 3.4 0.5 0.2 0.2 2.7 0.8 1.6 0.2 1.3 12.9 1.9 1.0 4.7 0.3 6.5 0.9 18.2 5.6 1.7 1.4 0.6 0.3 0.4 0.7 1.5 3.2 0.0 0.3 0.0 0.9 5.0 0.3 6.9 7.1 7.7 11.8 1.0 10.8 0.0 12.6 13.2 2.3 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 21.4 26.7 13.8 36.5 28.7 12.4 10.9 12.0 11.6 11.3 12.1 20.4 0.1 0.0 0.0 3.3 0.5 0.1 0.3 0.1 0.0 0.0 0.3 0.0 1.4 0.0 0.1 0.0 0.0 0.6 0.1 51.4 0.0 0.1 45.4 0.3 2.4 0.5 0.0 0.8 23.7 0.7 0.5 0.3 34.1 0.3 0.0 1.0 0.4 0.3 0.2 0.0 0.8 12.0 0.0 0.0 0.0 166.4 2.5 0.4 0.0 1.9 0.0 7.9 0.0 1.5 2.9 0.8 16.1 1.5 0.1 0.1 35.8 0.1 0.1 0.2 6.6 0.3 0.5 14.4 4.9 0.0 0.0 0.1 0.4 0.1 18.7 0.2 ITPR1 "ACV, Insp3r1, IP3R1, PPP1R94, SCA15, SCA16, SCA29" ENSG00000150995 "Inositol 1,4,5-trisphosphate receptor type 1" Q14643 3 4493345-4847840 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Mental retardation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 290.2;Inhibitory neurons: 183.1;Microglial cells: 84.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 49.9" "Immune cell enhanced" "Detected in many" "naive B-cell: 13.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 76.4;HEL: 41.1;HeLa: 74.9;HMC-1: 40.0;U-87 MG: 56.7" "Region enhanced" "Detected in all" "cerebellum: 697.2" "Region enhanced" "Detected in all" "cerebellum: 208.8" "HPA014765, HPA016487" Approved Approved Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA014765: AB_1851843, HPA016487: AB_1851842" "unprognostic (1.92e-1)" "unprognostic (5.04e-2)" "unprognostic (1.34e-1)" "unprognostic (1.75e-1)" "unprognostic (2.16e-2)" "unprognostic (3.61e-2)" "unprognostic (1.60e-1)" "unprognostic (1.12e-1)" "unprognostic (1.12e-1)" "unprognostic (3.17e-2)" "unprognostic (1.92e-2)" "unprognostic (2.08e-1)" "unprognostic (2.77e-2)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.43e-4)" "unprognostic (2.40e-1)" 10.6 12.0 1.8 11.8 12.0 7.2 17.3 49.9 20.1 11.5 15.6 19.5 4.5 36.5 10.0 10.6 27.1 14.1 10.1 5.9 0.0 13.9 3.9 13.7 11.2 0.0 0.5 25.3 6.7 45.3 16.0 8.0 0.0 21.7 6.3 3.9 16.1 27.9 3.0 5.0 11.5 24.5 0.0 9.2 11.1 4.5 0.0 10.3 31.7 5.3 10.5 27.9 11.8 6.1 0.4 4.1 1.0 3.0 27.7 1.9 11.8 0.9 0.5 1.3 0.8 1.3 1.2 14.5 0.6 1.9 6.5 0.1 2.2 2.6 2.1 76.4 3.2 41.1 74.9 3.5 27.4 17.7 40.0 9.2 4.0 5.8 1.1 7.6 7.2 8.4 7.9 13.9 3.7 1.8 7.2 3.0 2.1 0.5 9.7 4.2 1.0 1.1 1.7 5.5 0.7 19.5 5.4 4.3 4.3 0.9 2.6 20.6 13.5 1.8 4.3 3.7 2.3 17.7 12.0 9.6 56.7 17.0 2.7 5.8 2.0 1.5 2.3 0.9 1.7 6.7 1.6 1.6 2.2 13.4 2.7 1.6 1.8 1.8 0.9 4.7 1.4 1.1 1.8 12.0 49.9 20.1 5.9 0.0 0.0 0.5 0.0 0.0 0.0 6.1 30.1 0.0 31.4 24.8 49.7 3.8 6.1 6.3 11.4 4.0 40.0 29.7 8.0 2.8 11.2 9.2 0.0 0.5 17.8 0.3 3.9 2.4 5.4 9.1 11.9 31.2 3.5 8.4 290.2 5.1 0.5 21.5 20.4 12.7 26.5 22.6 36.0 2.0 4.7 1.7 183.1 1.3 2.0 12.9 17.4 7.9 30.1 23.9 7.2 84.3 14.2 4.3 6.2 25.1 12.7 1.5 1.2 52.6 8.8 5.4 0.3 3.9 13.1 1.5 39.5 8.8 28.2 1.5 2.9 4.9 3.1 1.0 25.7 22.0 0.8 3.3 ITPR3 IP3R3 ENSG00000096433 "Inositol 1,4,5-trisphosphate receptor type 3" Q14573 6 33620365-33696574 "Human disease related genes, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 123.0;Gastric mucus-secreting cells: 127.4;Late spermatids: 220.4;Pancreatic endocrine cells: 89.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 164.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA003915, HPA064704" Approved Uncertain Vesicles No Yes "Cluster 44: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA003915: AB_1851845, HPA064704: " "unprognostic (2.57e-1)" "unprognostic (2.81e-2)" "unprognostic (1.52e-2)" "unprognostic (2.30e-1)" "unprognostic (5.40e-2)" "unprognostic (1.24e-1)" "unprognostic (2.08e-2)" "unprognostic (6.14e-2)" "unprognostic (3.35e-1)" "unprognostic (3.08e-2)" "unprognostic (4.14e-3)" "unprognostic (1.88e-1)" "unprognostic (6.44e-3)" "unprognostic (5.01e-2)" "unprognostic (1.74e-1)" "unprognostic (8.89e-2)" "unprognostic (2.43e-2)" 16.3 11.4 5.5 17.0 5.0 6.1 14.6 3.8 5.3 18.0 3.7 26.2 29.1 8.5 13.1 18.1 14.0 15.3 15.0 3.8 3.9 16.4 2.2 30.6 20.4 5.6 5.0 13.5 11.3 2.8 7.4 4.3 5.2 13.9 18.4 0.8 18.5 11.2 4.5 58.9 35.1 4.7 4.7 39.8 41.5 15.4 7.0 14.3 54.0 5.1 21.0 12.1 24.0 3.9 73.7 34.0 6.3 0.3 6.2 19.3 40.9 24.8 62.8 30.5 27.4 46.7 55.9 62.6 26.1 17.9 76.1 70.9 28.6 66.7 15.7 36.8 24.0 0.1 102.6 52.0 14.1 11.3 7.9 14.0 59.2 76.7 164.7 66.5 52.1 24.5 25.0 19.7 33.3 35.0 19.0 6.4 6.2 55.8 49.4 29.0 0.1 37.1 107.6 50.9 57.3 2.1 42.8 61.6 60.2 6.9 21.2 5.9 71.8 41.1 20.1 53.1 55.2 13.5 14.3 29.4 32.8 16.6 24.1 0.8 0.0 0.0 0.8 0.0 0.6 0.4 0.4 0.5 0.0 0.6 0.4 0.5 0.0 0.0 0.0 0.0 0.7 0.2 5.5 5.0 3.8 5.3 3.8 3.9 5.6 5.0 5.2 4.7 7.0 3.9 12.4 48.1 58.9 0.3 13.5 26.5 10.9 27.9 18.2 1.5 9.3 9.9 2.7 12.8 20.2 31.3 0.0 0.3 10.9 52.9 0.0 28.4 123.0 19.1 9.1 18.2 23.9 6.6 1.1 30.2 6.3 9.2 127.4 43.1 0.0 0.2 12.5 0.4 0.5 0.0 1.6 41.6 10.2 0.6 6.9 220.4 23.3 2.6 12.4 23.4 3.2 0.4 4.1 0.5 0.4 89.7 41.6 13.9 18.7 20.5 45.9 0.2 12.1 1.2 6.6 3.9 3.3 1.6 3.2 14.5 25.4 0.5 13.1 5.8 35.6 20.7 ITPRIP "bA127L20.2, DANGER, KIAA1754" ENSG00000148841 "Inositol 1,4,5-trisphosphate receptor interacting protein" Q8IWB1 10 104309698-104338465 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 203.2" "Cell type enhanced" "Detected in many" "Adipocytes: 98.0;Hepatic stellate cells: 82.1;Squamous epithelial cells: 108.4;Suprabasal keratinocytes: 72.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 30.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 103.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA043626 Uncertain Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "HPA043626: AB_10963078" "unprognostic (2.45e-2)" "unprognostic (3.06e-1)" "unprognostic (1.59e-2)" "unprognostic (3.22e-2)" "unprognostic (1.08e-2)" "unprognostic (4.20e-1)" "unprognostic (7.87e-2)" "prognostic unfavorable (3.59e-4)" "unprognostic (9.74e-2)" "unprognostic (1.87e-1)" "unprognostic (2.64e-2)" "unprognostic (4.00e-2)" "unprognostic (5.37e-3)" "unprognostic (1.01e-3)" "unprognostic (2.65e-1)" "unprognostic (2.75e-1)" "unprognostic (2.11e-3)" 36.3 13.7 5.7 16.9 5.9 203.2 25.4 5.3 10.5 31.6 15.5 13.6 3.1 16.3 3.7 52.9 15.1 21.2 72.5 5.5 6.6 18.0 13.3 38.5 10.4 8.0 6.3 29.1 9.4 8.0 15.9 26.8 6.4 14.0 5.0 1.7 14.1 9.0 10.1 66.3 8.8 18.2 7.0 12.6 12.3 7.4 8.0 12.8 21.1 10.4 11.9 23.7 43.5 7.7 6.4 16.1 19.2 8.6 32.8 31.4 10.9 35.0 75.9 25.8 32.0 1.2 2.8 11.2 7.7 22.5 51.2 20.7 6.5 17.4 26.6 9.6 7.6 6.6 24.6 4.9 64.3 15.9 12.3 29.2 103.5 53.8 42.8 29.9 48.7 11.4 28.4 21.5 32.0 2.7 3.1 17.0 14.3 2.2 17.9 14.3 9.9 6.8 10.6 2.8 10.7 7.0 6.7 7.8 16.0 11.6 0.6 11.8 82.7 51.9 13.6 34.5 34.5 7.8 9.8 7.3 38.0 27.9 24.8 4.4 9.5 14.0 4.5 5.8 4.5 2.5 2.7 2.6 6.2 2.8 3.2 2.9 30.6 5.0 5.8 4.2 2.3 21.3 5.7 5.9 5.3 10.5 5.5 6.6 8.0 6.3 6.4 7.0 8.0 7.7 98.0 3.2 8.3 1.3 9.0 37.9 15.3 13.2 44.3 0.0 3.0 2.4 7.8 1.5 9.0 3.7 0.0 7.3 37.0 1.7 0.0 3.7 6.3 11.7 10.0 42.5 0.0 8.8 0.6 2.4 22.6 15.5 3.6 46.7 20.3 3.6 82.1 2.3 10.8 0.0 0.4 2.6 2.0 17.2 20.6 1.6 5.0 28.1 8.8 6.5 7.0 3.8 10.3 0.5 0.9 3.0 0.5 5.7 13.6 5.8 0.2 0.5 5.2 0.6 13.1 6.3 14.7 8.1 1.8 108.4 72.7 5.1 23.8 4.4 1.1 20.5 ITSN2 "KIAA1256, PRO2015, SH3D1B, SH3P18, SWA, SWAP" ENSG00000198399 "Intersectin 2" Q9NZM3 2 24202864-24360536 "Predicted intracellular proteins" "Differentiation, Endocytosis, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036475 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 10: Non-specific - Unknown function" "Vesicles, Plasma membrane" "HPA036475: AB_10670718" "unprognostic (2.36e-1)" "unprognostic (1.28e-1)" "unprognostic (1.24e-1)" "unprognostic (5.95e-2)" "unprognostic (4.64e-1)" "prognostic favorable (2.98e-4)" "unprognostic (3.32e-2)" "unprognostic (3.83e-2)" "unprognostic (2.77e-1)" "unprognostic (1.66e-1)" "unprognostic (2.69e-2)" "unprognostic (1.02e-1)" "unprognostic (1.66e-1)" "unprognostic (2.39e-1)" "unprognostic (2.72e-2)" "unprognostic (2.41e-2)" "unprognostic (2.12e-2)" 23.1 21.4 11.0 35.8 11.1 73.6 15.3 6.6 12.3 22.1 17.5 19.5 17.6 19.5 12.9 36.7 15.4 19.0 20.0 10.3 10.3 21.2 27.4 27.0 53.3 12.1 12.5 16.4 67.0 18.7 16.2 24.7 11.8 17.8 20.1 16.0 18.4 15.0 23.3 26.5 22.4 18.0 9.4 43.3 24.7 15.2 15.3 30.0 50.7 18.9 50.9 22.2 24.5 15.7 41.2 19.7 4.8 14.2 13.6 18.1 43.5 24.5 22.8 11.1 13.2 19.2 21.4 63.6 21.2 20.4 32.7 18.2 21.9 15.5 18.3 50.8 21.0 86.1 12.6 21.4 22.9 44.7 47.6 14.2 17.7 19.4 33.7 21.1 35.3 23.7 25.0 46.7 17.6 16.9 18.4 21.7 8.9 24.9 19.1 22.8 55.7 19.0 19.6 76.0 3.3 9.9 19.4 20.6 29.5 19.2 14.1 23.7 49.1 23.6 20.6 19.6 22.9 50.6 60.4 65.0 18.8 40.4 21.0 69.6 30.4 56.2 31.1 37.0 32.8 68.7 26.8 27.7 28.7 73.1 27.4 24.6 112.8 26.5 59.3 18.9 31.2 20.3 11.0 11.1 6.6 12.3 10.3 10.3 12.1 12.5 11.8 9.4 15.3 15.7 62.6 96.1 103.3 64.6 143.2 51.7 82.0 21.7 41.5 23.7 21.9 20.2 70.5 22.8 48.5 29.5 20.9 26.1 88.6 42.5 17.6 53.0 4.3 42.8 21.5 62.8 24.5 33.2 114.7 75.5 35.3 40.7 53.0 62.1 103.9 30.4 39.3 27.8 42.4 13.5 98.2 28.6 26.4 93.1 111.1 7.6 30.1 102.2 24.9 132.1 107.1 16.0 105.0 104.0 140.5 88.3 48.4 18.0 85.2 74.9 40.1 27.0 35.3 33.2 13.1 54.2 40.3 95.6 58.8 36.4 58.1 24.2 94.9 28.3 24.6 116.6 JAG2 ENSG00000184916 "Jagged canonical Notch ligand 2" Q9Y219 14 105140982-105168824 "Predicted membrane proteins" "Notch signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 56.1;Basal respiratory cells: 30.9;Basal squamous epithelial cells: 27.3;Breast myoepithelial cells: 26.4;Endothelial cells: 34.2;Horizontal cells: 26.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 62.6;HBEC3-KT: 21.0;SCLC-21H: 31.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025481, HPA030636, HPA050567" Approved Supported Vesicles,Cytosol NA NA 370000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles Cytosol "CAB025481: , HPA030636: AB_10602607, HPA050567: AB_2681178" "unprognostic (6.74e-2)" "unprognostic (4.49e-2)" "unprognostic (4.28e-2)" "unprognostic (6.97e-3)" "unprognostic (3.50e-1)" "unprognostic (2.13e-2)" "unprognostic (1.01e-1)" "unprognostic (6.84e-2)" "unprognostic (1.18e-2)" "unprognostic (2.62e-1)" "unprognostic (1.67e-2)" "unprognostic (9.19e-2)" "unprognostic (8.47e-3)" "unprognostic (1.46e-1)" "unprognostic (2.58e-1)" "unprognostic (2.39e-1)" "unprognostic (2.17e-1)" 7.2 1.0 4.0 1.3 3.6 0.1 9.6 0.9 5.0 4.6 0.5 3.1 1.1 5.3 0.4 8.8 5.3 1.8 12.8 3.5 7.4 4.3 0.9 5.1 0.7 4.6 4.4 1.5 6.8 1.5 17.4 3.0 6.8 8.1 0.2 0.8 7.8 2.8 9.7 19.5 4.0 1.1 2.5 2.0 3.0 3.2 6.5 1.6 4.7 2.8 0.6 5.2 6.8 1.6 16.8 6.7 0.4 1.7 0.0 0.0 20.0 0.2 0.1 0.0 0.0 5.6 20.1 0.0 13.8 0.0 0.1 62.6 4.0 21.0 0.0 2.3 9.7 0.0 20.0 0.0 0.2 0.1 3.9 0.2 9.9 0.0 2.3 0.2 5.1 0.9 4.1 0.0 0.0 7.6 0.0 0.0 2.0 2.1 2.3 5.3 3.9 7.2 0.1 4.4 31.4 1.0 5.6 1.3 0.2 0.3 15.8 2.5 17.2 0.1 1.7 0.0 0.2 0.9 0.1 0.1 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 3.6 0.9 5.0 3.5 7.4 4.6 4.4 6.8 2.5 6.5 1.6 56.1 6.4 3.2 1.0 0.2 23.3 7.6 30.9 27.3 2.7 3.8 26.4 6.7 2.8 7.6 0.0 25.0 2.2 2.2 2.7 0.0 3.9 0.1 16.5 0.9 34.2 0.0 0.0 12.1 2.7 1.0 1.8 2.0 7.4 0.0 1.1 7.9 0.6 0.7 26.9 9.9 3.6 4.1 0.8 2.9 1.0 1.5 1.1 7.2 15.0 1.3 0.6 1.0 0.5 1.1 3.3 2.1 0.7 0.9 4.4 8.2 0.3 11.5 4.8 0.0 3.7 3.7 0.8 13.5 6.0 6.8 1.4 3.4 0.3 2.7 1.5 JAGN1 "FLJ14602, GL009" ENSG00000171135 "Jagunal homolog 1" Q8N5M9 3 9890574-9894349 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067610 Approved Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA067610: " "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" "unprognostic (1.86e-3)" "unprognostic (1.97e-2)" "unprognostic (1.77e-1)" "unprognostic (1.95e-1)" "unprognostic (2.92e-3)" "unprognostic (1.57e-1)" "unprognostic (2.37e-2)" "unprognostic (6.36e-3)" "unprognostic (9.93e-3)" "unprognostic (2.70e-1)" "unprognostic (1.11e-1)" "unprognostic (1.44e-1)" "unprognostic (1.29e-1)" "unprognostic (3.65e-2)" "unprognostic (2.49e-1)" 29.6 43.5 21.3 15.7 22.3 12.1 26.6 23.8 28.9 21.9 24.6 26.3 27.0 23.4 39.7 19.4 25.7 16.4 22.9 21.6 23.1 30.1 62.6 17.4 19.2 22.5 22.3 25.5 40.2 31.5 17.8 20.6 22.5 20.9 30.2 19.9 24.0 20.8 36.1 27.6 26.4 20.5 22.9 17.6 30.8 14.1 22.7 24.0 17.8 30.1 23.6 23.0 21.0 23.6 32.7 54.0 39.8 23.9 116.9 121.5 128.3 43.8 65.2 49.4 49.6 40.6 43.1 51.4 19.6 44.2 54.0 28.1 63.1 59.5 48.9 38.4 65.7 62.4 55.7 73.7 99.4 45.6 37.3 115.3 89.4 63.6 73.2 51.0 47.0 45.8 65.0 34.5 59.2 99.0 37.8 80.5 50.1 65.3 74.3 31.0 32.5 64.4 73.3 45.9 25.0 46.4 29.6 31.8 58.1 35.8 50.4 56.8 39.9 26.2 28.1 29.3 35.4 60.2 94.5 60.7 33.1 55.7 44.9 100.9 61.8 31.1 48.1 48.6 50.5 52.5 46.8 45.9 57.4 53.3 50.9 48.0 24.9 51.9 37.9 58.1 54.7 67.9 21.3 22.3 23.8 28.9 21.6 23.1 22.5 22.3 22.5 22.9 22.7 23.6 28.7 32.1 17.5 5.2 38.6 27.5 47.8 84.1 30.7 27.3 53.0 58.8 14.1 55.8 43.5 38.6 10.4 74.7 30.8 49.5 21.5 80.6 3.2 33.0 33.5 36.3 25.8 30.9 4.8 98.1 80.1 37.9 30.1 22.9 8.2 36.5 42.8 52.4 55.8 23.5 5.7 55.2 59.0 40.7 22.5 6.8 39.4 29.8 37.4 4.7 75.3 52.3 50.4 8.0 8.0 73.5 55.7 38.7 35.3 66.2 114.2 55.9 40.6 23.3 46.0 31.6 31.7 66.0 51.2 35.8 36.8 52.9 31.3 48.8 58.3 39.2 JCAD KIAA1462 ENSG00000165757 "Junctional cadherin 5 associated" Q9P266 10 30012803-30115494 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 106.8;Endothelial cells: 30.3;Granulosa cells: 72.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 29.3;HUVEC TERT2: 29.9;LHCN-M2: 24.9;TIME: 67.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017956 Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Cell Junctions" "HPA017956: AB_1852408" "unprognostic (1.78e-1)" "unprognostic (8.33e-2)" "unprognostic (5.37e-2)" "unprognostic (8.07e-2)" "unprognostic (6.32e-2)" "unprognostic (7.09e-2)" "unprognostic (9.36e-2)" "unprognostic (1.28e-1)" "unprognostic (1.16e-1)" "unprognostic (4.93e-2)" "unprognostic (1.33e-1)" "unprognostic (3.08e-2)" "prognostic unfavorable (2.54e-4)" "prognostic unfavorable (2.01e-4)" "unprognostic (1.41e-1)" "unprognostic (1.13e-2)" "unprognostic (1.34e-2)" 31.2 7.5 13.5 5.2 21.2 0.1 13.0 5.1 13.0 6.5 3.1 36.0 1.4 17.3 7.5 5.9 12.5 10.4 18.3 10.8 7.2 6.7 1.8 24.2 3.5 12.5 8.4 10.9 16.9 4.9 4.5 33.6 10.1 7.8 3.9 13.1 2.4 9.5 9.9 3.7 3.7 17.3 7.3 0.9 4.5 14.0 13.3 6.1 13.6 14.8 1.8 18.3 4.4 8.1 15.3 6.7 5.9 0.0 3.7 0.9 8.6 8.1 8.5 1.2 2.0 2.6 0.1 0.0 0.6 29.3 1.7 0.3 1.6 0.5 3.3 1.7 3.6 0.0 0.0 0.1 16.0 0.0 1.0 9.1 0.2 19.9 1.5 0.5 29.9 0.4 0.0 0.0 24.9 0.5 0.0 0.7 1.2 0.9 10.2 0.0 3.3 0.0 1.2 0.3 0.8 0.1 0.3 0.1 0.0 8.4 0.0 1.4 67.8 14.9 3.6 4.7 0.7 6.2 0.8 0.0 3.5 10.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 21.2 5.1 13.0 10.8 7.2 12.5 8.4 10.1 7.3 13.3 8.1 106.8 0.0 3.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 16.4 0.0 1.3 8.5 30.3 0.0 0.0 0.0 0.4 0.9 2.2 0.0 0.8 1.3 72.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 2.9 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 3.4 0.2 7.1 0.0 0.0 JKAMP "C14orf100, CDA06, HSPC213, HSPC327, JAMP" ENSG00000050130 "JNK1/MAPK8 associated membrane protein" Q9P055 14 59484443-59505410 "Cancer-related genes, Predicted membrane proteins" "Unfolded protein response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 174.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031172, HPA071650" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles Nucleoplasm "HPA031172: AB_10670563, HPA071650: AB_2686429" "unprognostic (1.48e-1)" "unprognostic (2.19e-2)" "unprognostic (4.95e-2)" "unprognostic (5.88e-2)" "unprognostic (2.54e-1)" "unprognostic (1.49e-3)" "prognostic unfavorable (3.09e-6)" "unprognostic (2.68e-1)" "unprognostic (3.52e-1)" "unprognostic (1.16e-1)" "unprognostic (3.09e-1)" "unprognostic (3.14e-1)" "prognostic favorable (1.36e-4)" "unprognostic (1.76e-1)" "unprognostic (2.27e-1)" "unprognostic (1.36e-1)" "unprognostic (1.73e-1)" 25.9 34.9 23.6 17.7 26.5 22.9 32.5 29.5 30.3 23.0 34.2 29.6 17.3 30.5 26.4 17.8 31.2 30.8 25.9 22.9 30.2 44.5 34.0 30.7 25.2 30.1 29.8 25.8 20.7 56.6 28.6 33.8 31.3 29.9 29.5 34.7 25.4 27.0 17.1 17.9 24.0 27.7 28.7 23.0 24.4 30.4 26.1 22.1 34.6 21.1 20.7 26.4 16.2 32.0 54.8 68.0 57.3 46.8 40.9 59.0 42.8 85.9 76.6 52.6 62.9 21.8 108.1 27.7 75.6 85.5 55.3 40.0 41.2 52.8 72.1 82.8 24.0 30.3 38.5 42.3 56.0 45.6 53.6 60.9 56.6 45.9 32.6 82.1 55.7 35.8 25.4 54.9 100.7 54.1 25.6 37.8 31.2 45.9 60.4 31.4 73.6 27.9 92.1 59.3 23.7 40.9 82.8 68.4 45.1 40.0 66.4 32.3 72.4 54.9 65.6 53.0 58.0 21.7 45.5 32.7 80.7 33.2 68.0 86.3 59.3 82.3 34.4 74.8 34.3 36.1 37.0 37.0 51.9 34.1 38.9 36.5 89.4 50.2 83.0 70.5 47.0 57.8 23.6 26.5 29.5 30.3 22.9 30.2 30.1 29.8 31.3 28.7 26.1 32.0 25.5 22.4 31.2 29.7 23.6 30.0 32.8 132.9 54.1 30.3 31.6 27.1 10.2 41.5 66.3 46.0 18.8 64.2 42.0 27.4 7.9 45.4 174.5 43.3 31.7 26.9 31.2 40.8 30.3 54.8 64.8 37.4 27.5 20.9 34.9 28.0 26.4 41.9 57.8 28.6 26.8 26.7 89.5 60.3 31.4 61.2 35.4 40.4 48.0 19.7 34.2 40.1 29.9 28.1 34.5 51.4 21.3 31.6 50.2 26.3 22.4 53.0 110.6 30.3 13.1 27.5 58.8 85.1 41.1 30.7 29.1 29.8 27.6 30.3 24.6 20.9 JMJD4 FLJ12517 ENSG00000081692 "Jumonji domain containing 4" Q9H9V9 1 227730425-227735411 "Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 74.0;Late spermatids: 204.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027260, HPA052861" Uncertain Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" Vesicles "HPA027260: AB_10602608, HPA052861: AB_2681975" "unprognostic (1.80e-1)" "unprognostic (1.37e-1)" "unprognostic (4.86e-2)" "unprognostic (2.29e-1)" "unprognostic (1.43e-1)" "unprognostic (2.86e-1)" "unprognostic (1.23e-1)" "unprognostic (6.19e-2)" "unprognostic (1.74e-2)" "unprognostic (4.31e-2)" "unprognostic (8.69e-3)" "unprognostic (8.68e-3)" "prognostic unfavorable (3.16e-4)" "unprognostic (4.45e-2)" "unprognostic (2.82e-1)" "unprognostic (2.05e-1)" "unprognostic (4.68e-1)" 6.8 12.8 8.5 4.8 7.9 3.6 7.1 7.7 9.4 6.2 8.1 6.2 4.3 8.1 4.8 6.8 7.0 4.1 7.4 8.6 8.4 7.4 11.9 5.2 6.9 9.0 9.2 7.9 9.6 5.8 10.0 4.0 9.3 9.7 2.4 1.6 8.7 5.6 10.2 6.0 6.2 4.2 8.3 9.0 5.9 14.8 8.6 6.5 6.4 4.7 4.4 6.8 4.6 8.9 18.4 26.4 8.4 9.3 9.0 5.1 31.0 11.3 11.6 17.0 10.4 22.6 15.2 24.3 16.8 10.7 9.1 18.1 5.8 17.9 2.0 13.2 29.4 14.9 13.3 17.8 15.8 15.7 7.1 9.0 11.1 16.2 11.8 6.7 8.8 17.5 19.7 7.8 8.3 15.4 19.5 8.3 14.6 13.9 42.2 17.8 10.3 21.9 10.1 16.7 16.4 11.1 10.8 37.4 14.5 4.3 30.2 16.9 7.7 8.6 8.8 10.6 21.0 14.5 5.0 9.3 8.6 7.6 24.1 3.2 7.2 2.8 11.1 7.4 12.2 8.7 8.4 7.7 6.6 8.6 13.1 11.4 0.7 14.3 4.1 13.2 10.2 8.0 8.5 7.9 7.7 9.4 8.6 8.4 9.0 9.2 9.3 8.3 8.6 8.9 7.0 6.4 7.2 4.6 7.9 4.1 8.0 8.6 1.8 14.0 16.6 13.2 3.7 4.3 7.4 7.3 0.0 13.1 7.2 8.8 5.9 21.7 74.0 5.2 11.0 6.9 9.0 13.9 4.4 28.9 14.0 9.7 10.7 4.9 7.0 12.7 6.8 14.5 16.9 11.8 3.3 6.9 2.0 7.6 2.1 204.9 11.5 6.1 12.4 2.8 11.0 12.2 13.4 3.0 2.1 23.7 5.6 4.1 14.7 11.0 12.9 12.5 7.7 14.7 6.6 6.7 8.2 36.1 7.5 7.4 4.7 9.6 7.3 13.3 7.3 7.5 JTB "hJT, PAR" ENSG00000143543 "Jumping translocation breakpoint" O76095 1 153974269-153977674 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006514 Approved Uncertain Vesicles NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA006514: AB_1079164" "unprognostic (1.33e-1)" "unprognostic (1.77e-1)" "unprognostic (8.01e-2)" "unprognostic (1.66e-1)" "unprognostic (1.08e-1)" "unprognostic (3.40e-1)" "unprognostic (5.66e-3)" "unprognostic (8.62e-3)" "unprognostic (5.60e-2)" "prognostic favorable (7.87e-4)" "unprognostic (1.00e-3)" "unprognostic (8.16e-2)" "prognostic unfavorable (6.65e-9)" "unprognostic (1.36e-1)" "unprognostic (4.25e-1)" "unprognostic (5.48e-2)" "unprognostic (2.58e-3)" 105.6 119.8 121.1 60.4 125.1 127.0 103.0 122.3 153.9 99.8 149.0 117.8 89.5 89.8 96.3 110.8 91.8 53.7 121.0 120.8 122.2 135.4 207.1 110.2 80.4 125.4 122.2 98.4 232.2 93.9 185.9 68.0 121.5 131.0 86.7 49.8 162.0 68.0 166.5 99.8 115.3 50.1 123.3 136.9 164.8 46.6 126.6 77.7 120.5 82.7 80.2 96.3 89.4 123.4 206.3 139.4 57.9 108.0 189.0 116.2 163.5 144.6 142.3 95.9 96.0 135.3 166.7 193.7 198.7 171.8 59.1 181.0 151.0 113.2 78.1 180.5 296.0 112.5 158.4 139.0 198.1 221.4 165.7 110.4 210.4 101.1 119.1 131.0 115.4 223.7 169.3 139.2 68.4 359.6 161.5 280.5 125.8 402.1 239.1 163.9 79.3 393.1 123.7 110.9 158.4 158.8 115.3 332.7 208.4 107.4 209.1 316.4 89.6 46.5 80.4 144.4 189.0 201.8 244.7 211.3 114.5 209.6 103.7 98.7 119.5 173.2 74.7 86.4 90.9 143.5 104.0 118.7 88.9 139.9 107.0 85.6 104.9 85.3 96.5 147.4 98.5 97.7 121.1 125.1 122.3 153.9 120.8 122.2 125.4 122.2 121.5 123.3 126.6 123.4 127.7 80.1 101.1 15.7 184.3 156.8 177.4 227.5 104.7 56.6 253.4 207.3 96.5 213.1 171.4 99.3 22.9 308.8 237.3 273.4 258.2 251.9 7.1 145.0 95.3 120.4 212.0 178.8 26.3 411.8 405.0 155.6 149.9 125.9 82.5 113.2 125.7 341.3 289.1 57.2 24.0 423.4 213.6 235.8 185.8 20.1 151.6 176.3 170.7 19.7 207.9 140.4 257.5 19.6 29.1 274.1 302.2 123.4 344.8 346.0 368.2 274.1 138.2 60.2 105.2 105.3 114.0 58.9 71.5 173.4 190.2 289.5 173.6 136.6 315.2 304.0 JUP "CTNNG, DP3, DPIII, PDGB, PKGB" ENSG00000173801 "Junction plakoglobin" P14923 17 41754604-41786931 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cancer-related genes, Cardiomyopathy, Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 952.2;skin 1: 932.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 315.9;Pancreatic endocrine cells: 356.2;Squamous epithelial cells: 318.3;Suprabasal keratinocytes: 383.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 13.1;eosinophil: 28.7;intermediate monocyte: 22.6;memory B-cell: 13.5;myeloid DC: 14.5;naive B-cell: 11.7;non-classical monocyte: 43.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 1090.1;OE19: 3919.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002139, HPA032047" Supported Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 64000000 "Cluster 14: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" Vesicles "CAB002139: AB_563468, HPA032047: AB_2674124" "unprognostic (3.96e-3)" "unprognostic (3.40e-1)" "unprognostic (2.32e-1)" "unprognostic (4.71e-3)" "unprognostic (2.49e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (8.11e-3)" "unprognostic (1.41e-2)" "unprognostic (9.85e-3)" "unprognostic (2.29e-3)" "unprognostic (9.60e-2)" "prognostic favorable (2.06e-10)" "unprognostic (2.50e-1)" "unprognostic (9.49e-2)" "unprognostic (9.05e-2)" "unprognostic (1.51e-2)" 46.5 16.0 13.6 23.6 21.6 20.7 68.6 20.8 18.9 243.7 25.8 94.9 88.1 57.0 15.3 952.2 69.9 39.8 145.1 14.6 14.3 120.7 70.9 57.1 15.7 20.7 16.2 46.2 59.6 19.9 37.3 51.5 19.6 68.0 49.0 4.7 226.4 41.8 110.8 932.4 95.7 23.1 14.8 22.7 86.3 12.5 16.2 29.6 86.4 62.2 92.0 68.7 432.6 33.6 268.8 217.8 21.7 18.5 0.2 0.1 330.6 15.3 89.2 5.9 5.2 332.6 289.0 5.4 157.8 9.7 7.5 1090.1 31.6 242.4 1.0 0.6 74.2 11.6 165.1 74.4 34.7 7.3 113.6 0.5 538.6 0.9 43.9 64.2 96.1 7.0 99.6 94.0 0.0 342.6 1.9 96.5 42.3 3919.9 36.2 313.5 0.2 202.5 165.8 674.0 52.2 38.6 33.8 652.1 1.9 98.6 545.9 8.0 152.4 0.3 14.8 6.8 5.1 8.2 31.2 5.5 1.5 12.7 2.6 3.9 13.1 28.7 0.0 22.6 0.0 13.5 0.0 0.2 14.5 11.7 0.2 0.1 0.6 0.8 43.8 4.5 0.1 5.7 13.6 21.6 20.8 18.9 14.6 14.3 20.7 16.2 19.6 14.8 16.2 33.6 56.9 60.9 36.8 4.6 10.6 196.9 218.5 104.5 100.2 1.9 87.3 77.0 87.8 48.6 80.9 132.4 4.2 98.9 1.1 315.9 27.4 212.2 28.5 112.6 21.1 55.2 66.8 3.4 0.5 135.4 167.3 25.6 136.1 247.0 11.4 16.5 41.4 34.1 14.4 0.0 1.6 125.0 81.4 7.7 32.7 8.3 5.0 10.9 12.4 2.8 6.3 18.2 0.0 7.1 13.6 356.2 223.7 0.0 3.9 220.1 141.1 35.6 45.7 4.3 6.6 37.4 18.8 2.5 4.5 318.3 383.3 185.7 6.1 3.2 129.2 301.6 KANSL3 "FLJ10081, KIAA1310, NSL3, Rcd1" ENSG00000114982 "KAT8 regulatory NSL complex subunit 3" Q9P2N6 2 96593170-96642787 "Metabolic proteins, Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035017, HPA035018" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 52: Non-specific - Ribosome" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm Vesicles "HPA035017: AB_2674414, HPA035018: AB_10601763" "unprognostic (2.19e-1)" "unprognostic (6.94e-2)" "unprognostic (5.62e-2)" "unprognostic (8.72e-3)" "unprognostic (3.28e-1)" "unprognostic (4.35e-3)" "prognostic unfavorable (5.34e-4)" "unprognostic (6.34e-2)" "unprognostic (1.41e-1)" "unprognostic (2.02e-1)" "unprognostic (3.01e-2)" "unprognostic (2.99e-2)" "unprognostic (2.04e-3)" "unprognostic (3.28e-1)" "unprognostic (1.92e-1)" "unprognostic (8.30e-3)" "unprognostic (4.99e-3)" 11.8 9.9 1.9 8.6 2.4 14.9 12.3 1.6 3.1 13.7 8.1 11.8 7.2 15.0 7.7 8.9 12.5 6.9 10.7 2.9 2.6 8.8 6.4 9.9 8.2 2.1 2.9 15.1 9.8 15.1 8.8 9.0 2.3 11.2 6.9 6.3 12.5 14.7 33.9 10.8 12.0 10.6 3.3 10.1 9.8 12.8 3.3 13.1 12.9 21.1 8.9 13.0 10.8 2.3 13.1 7.9 26.0 19.4 10.6 6.4 11.4 9.7 15.2 20.1 21.4 15.1 7.8 18.1 14.6 16.2 14.7 8.2 18.8 9.4 17.5 12.8 14.8 26.0 8.1 16.2 15.0 17.4 9.0 15.0 5.8 12.8 11.4 12.0 11.0 21.0 18.6 12.8 12.8 6.9 32.3 13.5 12.5 6.7 12.8 26.2 16.5 10.6 12.4 12.7 26.8 16.9 12.3 11.8 11.8 14.7 11.4 5.5 15.9 13.5 11.8 9.8 8.9 10.1 6.7 15.7 7.0 19.9 12.2 2.4 1.3 0.5 2.8 1.5 2.1 1.6 1.7 2.9 0.7 1.5 1.2 2.3 0.2 3.1 1.3 0.7 1.1 1.7 1.9 2.4 1.6 3.1 2.9 2.6 2.1 2.9 2.3 3.3 3.3 2.3 11.6 44.8 30.8 29.0 10.5 4.6 9.9 8.1 9.1 15.0 14.8 12.2 23.8 10.0 18.8 11.0 43.8 8.1 10.0 15.0 3.9 10.5 13.4 13.0 13.7 12.1 13.1 6.7 35.6 9.6 4.3 12.7 17.3 13.5 18.3 33.1 15.7 12.7 8.1 15.2 36.2 18.4 10.2 12.5 5.6 28.6 9.9 11.2 7.2 16.9 13.7 10.2 9.2 29.7 37.3 13.2 7.9 12.8 10.6 10.3 10.7 5.8 13.1 29.5 13.1 16.0 13.6 23.3 9.7 11.3 6.5 11.1 14.2 18.3 15.6 10.1 KAT5 "cPLA2, ESA1, HTATIP, HTATIP1, PLIP, TIP60, ZC2HC5" ENSG00000172977 "Lysine acetyltransferase 5" Q92993 11 65711996-65719604 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Growth regulation, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016953, HPA074328" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "Vesicles, Cytosol" "HPA016953: AB_1851277, HPA074328: " "unprognostic (2.20e-1)" "unprognostic (3.58e-1)" "unprognostic (3.59e-2)" "unprognostic (2.74e-1)" "unprognostic (9.61e-2)" "unprognostic (7.16e-2)" "unprognostic (1.29e-3)" "unprognostic (1.20e-1)" "unprognostic (2.01e-1)" "unprognostic (2.74e-1)" "unprognostic (2.13e-1)" "unprognostic (2.54e-1)" "prognostic favorable (1.10e-13)" "unprognostic (1.37e-1)" "unprognostic (2.55e-1)" "unprognostic (1.85e-1)" "unprognostic (8.54e-2)" 31.6 30.0 38.7 23.8 41.0 52.9 32.1 41.7 48.8 39.5 38.6 43.6 21.6 45.1 33.7 34.9 44.9 20.5 32.4 37.9 38.9 32.9 26.3 29.5 28.0 40.0 39.5 39.2 32.7 45.6 33.7 29.9 41.2 33.1 27.0 31.0 29.6 36.3 42.8 47.6 32.2 35.2 40.0 34.3 35.9 45.2 39.9 39.3 38.2 34.6 30.2 39.5 34.8 43.8 37.2 44.1 40.1 29.6 31.3 32.7 41.1 26.7 43.6 44.0 38.0 32.6 42.2 34.3 36.2 47.4 47.5 30.8 50.8 45.1 26.4 44.4 32.5 50.6 36.3 38.9 44.6 55.7 56.4 35.2 49.7 28.9 59.0 33.7 28.1 39.1 52.5 51.1 42.0 68.2 45.7 62.3 33.9 26.8 28.4 38.2 26.5 63.3 40.6 56.2 37.1 38.9 25.4 46.5 51.2 20.8 45.9 34.2 36.3 33.9 30.4 27.6 28.0 38.7 43.7 50.4 29.7 27.0 29.3 42.7 33.6 58.8 33.4 32.0 29.6 28.2 28.8 34.2 34.1 30.4 36.5 29.8 34.8 35.8 34.6 20.9 31.0 36.4 38.7 41.0 41.7 48.8 37.9 38.9 40.0 39.5 41.2 40.0 39.9 43.8 17.6 12.8 17.5 10.7 26.0 21.2 44.2 60.2 17.6 44.9 17.3 15.0 1.0 25.8 33.8 29.5 31.3 51.3 25.6 27.1 35.2 42.2 11.1 20.2 14.2 18.7 30.4 12.4 7.5 51.5 42.6 21.1 20.4 19.8 33.7 27.0 18.2 10.9 36.3 38.7 8.7 25.1 42.7 17.6 15.2 11.1 28.0 20.4 42.7 3.7 38.8 40.3 33.0 7.1 13.8 39.4 30.6 38.7 10.4 24.2 23.3 32.6 30.0 44.8 46.0 27.6 27.0 61.1 27.8 14.6 21.3 102.5 21.6 29.2 26.2 31.0 KBTBD4 "BKLHD4, FLJ10450, HSPC252" ENSG00000123444 "Kelch repeat and BTB domain containing 4" Q9NVX7 11 47572197-47578976 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037792, HPA037793" Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Vesicles, Cytosol" "HPA037792: AB_10671633, HPA037793: AB_2675671" "unprognostic (5.52e-2)" "unprognostic (2.23e-1)" "unprognostic (8.36e-3)" "unprognostic (1.15e-1)" "unprognostic (3.30e-2)" "unprognostic (7.32e-2)" "unprognostic (1.21e-1)" "unprognostic (2.09e-1)" "unprognostic (8.73e-3)" "unprognostic (2.78e-1)" "unprognostic (4.04e-2)" "unprognostic (7.22e-2)" "prognostic favorable (2.70e-7)" "unprognostic (4.18e-1)" "unprognostic (1.32e-1)" "unprognostic (2.07e-1)" "unprognostic (4.25e-2)" 10.2 13.9 5.8 4.6 6.2 8.7 10.0 7.2 6.2 10.0 6.4 12.8 4.2 13.2 8.8 9.2 10.6 4.6 10.6 5.9 5.8 9.9 8.3 8.3 6.4 5.5 5.7 10.9 8.4 12.4 13.0 4.3 5.6 8.5 6.2 7.4 10.3 6.7 24.3 13.1 10.5 6.7 5.7 10.9 10.4 14.5 5.7 7.9 9.3 11.0 8.4 11.3 8.3 6.0 5.0 11.8 13.0 10.2 7.8 10.6 3.7 9.0 11.8 12.8 11.2 4.0 9.8 9.6 4.8 11.6 9.2 8.5 7.5 13.3 10.9 12.6 10.7 7.2 15.9 5.7 5.8 15.3 14.5 9.6 9.1 5.4 6.9 8.8 13.4 6.7 5.4 7.6 10.2 13.1 11.2 4.6 6.4 14.0 7.6 10.2 17.0 5.4 13.8 11.9 17.2 11.0 7.7 10.4 6.5 4.3 17.4 4.8 10.7 7.9 8.4 12.1 9.0 10.3 20.3 14.2 11.5 4.2 8.8 11.6 4.6 11.7 12.5 3.8 13.8 11.6 9.8 11.4 5.9 10.9 10.6 11.4 8.3 13.5 4.1 2.5 12.8 10.4 5.8 6.2 7.2 6.2 5.9 5.8 5.5 5.7 5.6 5.7 5.7 6.0 6.2 6.4 3.6 3.3 9.6 4.8 6.2 16.4 7.4 14.0 6.9 4.4 0.1 8.6 11.3 11.0 8.4 12.3 9.7 6.9 23.5 13.9 14.5 10.2 5.2 9.0 7.2 9.5 5.7 13.7 7.3 5.8 1.5 4.6 10.8 6.8 7.5 8.8 8.1 13.5 6.6 4.0 20.3 4.1 2.9 18.3 5.0 4.3 1.8 3.7 11.4 24.9 10.3 2.5 4.6 9.0 2.9 9.4 5.8 4.1 6.3 10.9 18.8 12.1 13.1 6.9 6.0 23.7 20.1 4.0 4.5 14.1 10.2 7.6 5.4 4.6 KCNAB1 "AKR6A3, hKvb3, hKvBeta3, KCNA1B, Kvb1.3" ENSG00000169282 "Potassium voltage-gated channel subfamily A member regulatory beta subunit 1" Q14722 3 156037701-156539138 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 52.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 85.8;Excitatory neurons: 108.6;Inhibitory neurons: 605.4;Oligodendrocyte precursor cells: 206.6;Oligodendrocytes: 97.5;Sertoli cells: 78.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HEL: 3.4;hTEC/SVTERT24-B: 5.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036110, HPA044550" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "Nucleoplasm, Plasma membrane" "HPA036110: , HPA044550: AB_10797032" "unprognostic (1.52e-1)" "unprognostic (3.73e-1)" "unprognostic (1.33e-1)" "unprognostic (2.98e-4)" "unprognostic (1.24e-2)" "unprognostic (1.64e-1)" "unprognostic (1.81e-1)" "unprognostic (2.83e-2)" "unprognostic (8.51e-2)" "unprognostic (3.72e-2)" "unprognostic (5.87e-2)" "unprognostic (9.70e-2)" "unprognostic (2.17e-3)" "unprognostic (2.60e-1)" "unprognostic (1.95e-1)" "unprognostic (1.06e-1)" "unprognostic (4.00e-1)" 15.8 6.3 12.7 1.2 52.7 1.6 7.3 15.5 17.3 8.4 4.2 4.1 1.7 5.4 12.8 2.2 4.3 2.9 5.5 25.9 11.6 1.8 2.6 3.3 0.9 7.2 12.1 2.9 4.0 2.0 1.8 1.3 7.2 22.4 1.8 12.8 3.9 19.2 2.0 2.2 2.7 2.7 8.4 5.2 1.6 3.1 14.1 1.8 28.7 5.1 0.3 2.9 5.0 15.4 0.5 0.5 0.7 0.2 0.0 0.0 1.4 1.2 0.0 0.0 0.1 0.9 0.1 0.4 0.7 0.0 0.3 0.3 0.0 0.0 0.0 0.4 1.0 3.4 0.6 1.6 0.0 1.0 0.2 0.0 0.0 5.2 0.0 1.1 2.1 0.5 0.1 0.3 0.2 0.1 0.3 0.6 1.1 1.5 0.2 0.6 0.7 2.8 0.0 0.2 0.8 0.8 0.3 0.6 0.7 0.5 0.8 0.5 2.2 0.8 0.5 1.4 1.2 1.8 0.4 0.4 2.6 1.1 1.0 0.8 0.1 0.0 0.4 0.2 0.8 0.2 0.4 0.3 0.2 0.2 0.3 0.3 0.0 0.3 0.3 1.2 0.5 0.1 12.7 52.7 15.5 17.3 25.9 11.6 7.2 12.1 7.2 8.4 14.1 15.4 7.2 0.0 0.0 7.5 0.7 0.8 0.3 0.0 0.0 85.8 1.4 1.4 4.3 0.0 0.7 0.0 31.3 0.1 0.5 0.1 0.0 0.4 13.7 0.6 2.4 2.8 0.0 0.0 108.6 0.0 0.0 3.8 0.0 2.1 0.0 0.4 0.7 0.0 4.6 0.0 605.4 0.0 0.0 11.1 1.0 7.0 0.0 1.2 1.8 24.4 0.0 2.7 0.0 206.6 97.5 0.0 0.0 2.6 2.3 0.2 0.0 0.1 0.0 6.7 78.9 1.3 73.3 0.3 4.2 1.2 0.9 0.1 0.5 0.2 0.0 0.2 KCNC1 Kv3.1 ENSG00000129159 "Potassium voltage-gated channel subfamily C member 1" P48547 11 17734774-17856804 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 47.3" "Group enriched" "Detected in some" 5 "Bipolar cells: 79.6;Excitatory neurons: 48.2;Inhibitory neurons: 120.2" "Group enriched" "Detected in some" 5 "glioma: 1.1;testis cancer: 0.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 3.2;neutrophil: 1.4" "Lineage enriched" "Detected in single" 6 "granulocytes: 3.2" "Cell line enhanced" "Detected in some" "HeLa: 1.6;RH-30: 3.7;SCLC-21H: 3.5;SH-SY5Y: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047634, HPA048249" Enhanced Approved "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 6: Brain - Smell perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Nuclear membrane" "Vesicles, Cytosol" "HPA047634: AB_2680109, HPA048249: " "unprognostic (1.79e-2)" "unprognostic (2.68e-1)" "unprognostic (1.33e-1)" "unprognostic (4.09e-3)" "unprognostic (1.12e-1)" "unprognostic (8.02e-2)" "unprognostic (2.40e-1)" "unprognostic (1.27e-1)" "unprognostic (8.37e-2)" "unprognostic (2.14e-1)" "unprognostic (7.04e-5)" "unprognostic (5.89e-2)" "unprognostic (7.32e-4)" "unprognostic (1.29e-1)" "unprognostic (5.44e-2)" "unprognostic (1.05e-2)" "unprognostic (7.83e-2)" 0.1 0.8 1.1 0.1 3.3 0.9 0.2 41.0 47.3 0.9 0.0 0.3 0.3 0.3 0.0 0.2 0.1 0.2 0.1 4.5 8.0 0.1 0.2 0.1 0.2 8.8 3.0 0.2 0.4 0.0 2.2 0.0 9.3 0.2 0.0 7.0 0.3 0.0 0.5 0.5 0.3 0.0 1.0 0.2 0.3 1.4 12.3 0.1 0.3 1.2 0.0 0.3 0.5 18.8 0.1 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.4 0.9 0.0 0.1 0.2 1.1 0.3 1.6 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.7 0.0 0.2 0.2 0.4 0.7 0.0 0.0 0.4 3.7 0.4 0.0 0.2 3.5 2.1 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 1.0 0.1 0.0 0.2 0.3 0.4 0.2 0.2 0.4 3.2 0.3 0.4 0.3 0.2 0.2 0.2 0.3 0.2 0.0 0.5 0.2 0.2 1.4 0.2 0.3 0.3 0.1 0.1 1.1 3.3 41.0 47.3 4.5 8.0 8.8 3.0 9.3 1.0 12.3 18.8 0.2 0.0 0.0 5.5 1.1 0.0 0.2 0.0 0.0 79.6 0.3 0.4 2.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.5 9.5 0.2 0.5 0.4 7.7 0.0 48.2 0.2 0.0 0.3 0.0 0.3 0.0 2.8 0.0 0.0 0.0 1.7 120.2 0.0 0.0 0.0 0.0 10.2 0.3 0.2 0.0 7.5 0.6 1.5 0.0 16.1 5.6 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 7.7 0.0 0.2 0.5 6.1 5.0 0.0 0.0 0.0 0.6 1.8 0.0 0.0 KCNF1 "IK8, KCNF, kH1, Kv5.1" ENSG00000162975 "Potassium voltage-gated channel modifier subfamily F member 1" Q9H3M0 2 10911934-10914225 "Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 24 "brain: 28.9;choroid plexus: 32.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 9.3;Extravillous trophoblasts: 14.4;Inhibitory neurons: 8.8;Oligodendrocyte precursor cells: 18.1;Syncytiotrophoblasts: 7.7" "Cancer enriched" "Detected in many" 7 "glioma: 27.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 14.3;MCF7: 5.1;T-47d: 6.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA014738, HPA062278" Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA014738: AB_1852114, HPA062278: AB_2732679" "unprognostic (2.54e-1)" "unprognostic (6.06e-3)" "unprognostic (1.37e-1)" "unprognostic (3.07e-2)" "unprognostic (4.39e-2)" "unprognostic (7.41e-4)" "unprognostic (1.54e-3)" "unprognostic (4.83e-5)" "unprognostic (1.57e-1)" "unprognostic (6.95e-2)" "unprognostic (1.60e-2)" "unprognostic (1.40e-1)" "unprognostic (2.96e-1)" "unprognostic (3.10e-4)" "unprognostic (2.37e-1)" "unprognostic (4.28e-2)" "unprognostic (4.08e-2)" 0.1 0.0 20.6 0.1 28.9 0.0 0.2 0.0 21.5 0.0 32.1 1.2 0.2 0.6 0.0 0.2 0.1 0.1 0.7 28.8 14.7 0.4 0.0 0.3 0.1 0.0 5.3 0.0 0.9 0.3 0.8 0.0 0.0 0.7 0.2 0.2 0.1 0.3 0.0 0.0 0.6 0.0 0.6 0.5 0.3 0.5 12.5 0.3 0.0 0.0 0.0 0.6 0.0 15.8 0.1 14.3 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 2.1 0.1 1.5 0.0 0.1 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.1 6.1 0.7 0.0 0.0 1.6 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.6 28.9 0.0 21.5 28.8 14.7 0.0 5.3 0.0 0.6 12.5 15.8 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.2 0.0 2.0 0.8 1.4 1.4 0.0 0.0 0.0 2.1 0.0 0.1 1.6 0.0 0.0 2.2 0.8 0.3 0.9 1.2 0.0 9.3 0.0 14.4 0.7 0.0 2.0 0.0 0.2 0.0 0.0 0.2 0.0 8.8 0.2 0.0 0.0 0.0 3.4 0.3 0.1 0.0 1.9 0.0 0.3 0.0 18.1 1.4 0.1 0.2 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 7.7 0.0 0.4 0.3 0.1 KCNG1 "K13, KCNG, kH2, Kv6.1" ENSG00000026559 "Potassium voltage-gated channel modifier subfamily G member 1" Q9UIX4 20 51003656-51023107 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.8;endometrium 1: 87.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 53.7;Granulosa cells: 34.0;Syncytiotrophoblasts: 97.0" "Cancer enhanced" "Detected in many" "urothelial cancer: 8.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 20 "naive B-cell: 7.1" "Lineage enriched" "Detected in single" 71 "B-cells: 7.1" "Cell line enhanced" "Detected in many" "hTCEpi: 53.5;U-138 MG: 40.4;WM-115: 34.6" "Group enriched" "Detected in many" 5 "amygdala: 20.6;basal ganglia: 19.1;cerebral cortex: 14.9;hippocampal formation: 18.1;white matter: 9.1" "Group enriched" "Detected in all" 5 "amygdala: 12.6;basal ganglia: 11.1;cerebral cortex: 22.4;hippocampal formation: 16.8" "HPA039530, HPA040024" Approved Approved Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA039530: AB_10795144, HPA040024: AB_10796338" "unprognostic (1.19e-1)" "unprognostic (4.47e-2)" "unprognostic (8.70e-2)" "unprognostic (3.49e-2)" "unprognostic (4.07e-2)" "unprognostic (5.05e-4)" "unprognostic (2.53e-2)" "unprognostic (3.89e-3)" "unprognostic (3.64e-2)" "unprognostic (3.43e-2)" "unprognostic (8.74e-2)" "unprognostic (8.89e-2)" "unprognostic (1.83e-9)" "unprognostic (1.52e-1)" "unprognostic (7.42e-2)" "unprognostic (1.60e-1)" "unprognostic (1.02e-2)" 0.4 3.0 17.3 2.2 26.7 0.0 0.4 0.0 21.7 17.9 0.1 5.0 0.2 87.4 0.8 6.7 19.2 0.9 1.3 14.9 0.6 0.5 0.2 0.3 2.2 28.9 46.8 0.7 2.7 4.1 0.8 7.1 3.2 5.6 0.8 0.1 2.2 12.8 0.0 0.5 5.3 4.1 1.0 2.7 0.7 9.5 1.2 0.2 0.2 0.0 0.9 3.4 6.2 1.1 0.9 3.6 2.7 13.3 1.5 3.4 0.2 11.6 0.1 6.7 5.3 0.2 0.2 0.0 7.1 3.5 18.8 3.4 1.7 3.5 6.9 0.4 4.7 0.0 13.6 0.0 23.2 0.0 0.4 6.8 53.5 25.7 26.1 1.3 1.8 0.1 0.2 0.0 0.6 13.4 0.0 0.4 13.7 0.0 25.0 0.0 0.0 0.0 0.0 4.1 3.9 15.0 25.5 29.3 19.9 4.3 2.1 1.9 0.7 40.4 23.9 0.3 3.4 0.1 0.0 0.0 11.8 1.0 34.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 17.3 26.7 0.0 21.7 14.9 0.6 28.9 46.8 3.2 1.0 1.2 1.1 0.2 3.2 1.1 0.3 10.5 1.1 11.0 0.6 13.6 0.3 1.1 2.3 1.1 7.2 0.9 0.0 0.0 53.7 0.0 7.5 0.0 2.6 18.2 9.3 2.0 1.2 0.0 0.0 2.0 0.0 2.7 1.5 0.5 15.9 0.0 34.0 0.4 0.3 3.3 1.7 2.2 0.6 0.0 0.0 0.3 20.3 1.5 0.3 0.0 1.0 0.0 0.2 1.0 0.0 0.6 0.2 3.4 4.1 0.0 18.1 12.8 0.1 0.9 0.2 0.0 1.1 7.1 12.7 0.7 5.4 0.3 97.0 0.4 0.3 0.4 9.9 KCNH1 "eag, eag1, h-eag, hEAG, Kv10.1" ENSG00000143473 "Potassium voltage-gated channel subfamily H member 1" O95259 1 210676823-211134165 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 17.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 533.5;Inhibitory neurons: 261.0;Oligodendrocytes: 116.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "LHCN-M2: 6.2;RH-30: 10.1;RPTEC TERT1: 6.0;SH-SY5Y: 12.9;SK-MEL-30: 12.9;T-47d: 9.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 34.0;cerebellum: 19.1;cerebral cortex: 23.9;hippocampal formation: 17.9;olfactory bulb: 8.9" "HPA014551, HPA019445, HPA076421" Enhanced Supported Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA014551: AB_2669038, HPA019445: AB_1852118, HPA076421: " "unprognostic (9.12e-2)" "unprognostic (4.82e-3)" "unprognostic (2.63e-1)" "unprognostic (6.70e-2)" "unprognostic (3.56e-1)" "unprognostic (3.63e-2)" "unprognostic (1.73e-1)" "unprognostic (9.36e-2)" "unprognostic (1.41e-1)" "unprognostic (1.98e-1)" "unprognostic (1.46e-2)" "unprognostic (2.77e-2)" "unprognostic (1.42e-3)" "unprognostic (1.17e-1)" "unprognostic (8.89e-2)" "unprognostic (1.36e-1)" "unprognostic (9.70e-2)" 0.2 0.9 6.8 0.4 9.2 0.0 0.2 9.5 17.9 0.7 2.7 0.5 0.3 0.4 0.2 0.1 0.6 0.2 0.0 11.2 5.3 0.1 0.1 0.0 0.0 4.8 4.4 0.1 0.2 0.0 0.7 0.3 4.0 0.5 0.3 0.3 0.1 0.1 0.2 0.1 0.8 0.2 4.0 0.0 0.5 1.5 4.9 0.2 0.1 0.6 0.0 0.2 0.4 8.3 0.0 2.1 0.4 0.1 0.0 0.1 0.1 1.0 0.2 2.1 2.4 0.0 0.0 0.0 0.0 1.4 2.4 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.5 0.1 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 6.2 0.2 0.0 0.0 0.2 0.0 0.0 0.0 10.1 0.0 6.0 0.0 0.4 12.9 2.4 0.2 12.9 1.7 9.2 0.0 0.0 1.6 0.2 2.0 1.2 0.0 0.0 0.0 0.2 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.8 9.2 9.5 17.9 11.2 5.3 4.8 4.4 4.0 4.0 4.9 8.3 0.2 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 11.2 0.2 2.8 0.1 0.0 0.0 533.5 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 261.0 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 7.5 0.0 0.0 0.0 19.1 116.6 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KCNIP1 KCHIP1 ENSG00000182132 "Potassium voltage-gated channel interacting protein 1" Q9NZI2 5 170353487-170736632 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.7;choroid plexus: 15.1;epididymis: 21.6" "Cell type enhanced" "Detected in some" "Astrocytes: 57.8;Horizontal cells: 50.5;Inhibitory neurons: 221.4;Microglial cells: 167.7;Oligodendrocyte precursor cells: 196.1" "Cancer enriched" "Detected in some" 18 "glioma: 22.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 24 "RPTEC TERT1: 58.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022864, HPA066717" Uncertain Approved Vesicles NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA022864: AB_1858712, HPA066717: " "unprognostic (7.75e-5)" "unprognostic (2.66e-2)" "unprognostic (6.78e-2)" "unprognostic (3.22e-4)" "unprognostic (4.51e-2)" "unprognostic (3.49e-1)" "unprognostic (1.25e-2)" "unprognostic (2.69e-1)" "unprognostic (5.46e-2)" "unprognostic (6.62e-3)" "unprognostic (4.74e-2)" "unprognostic (7.52e-2)" "unprognostic (2.55e-1)" "unprognostic (2.58e-2)" "unprognostic (1.63e-1)" "unprognostic (2.39e-1)" "unprognostic (6.05e-2)" 0.5 4.2 23.5 0.5 26.5 0.0 1.0 19.4 28.3 2.7 15.1 0.7 0.2 1.6 21.6 0.3 1.7 1.8 0.4 21.8 32.6 3.8 0.1 1.0 0.5 24.3 26.6 0.3 1.4 1.3 1.0 1.2 24.7 1.5 0.5 5.8 0.4 5.6 0.1 0.4 0.3 1.1 28.7 1.5 0.4 2.7 32.7 0.1 0.7 0.2 0.4 0.5 0.6 19.6 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 58.7 0.0 0.6 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.5 26.5 19.4 28.3 21.8 32.6 24.3 26.6 24.7 28.7 32.7 19.6 0.0 0.0 0.0 57.8 0.0 0.4 0.1 0.0 0.0 0.4 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 2.0 1.2 0.0 0.0 18.6 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 50.5 221.4 0.0 0.0 0.0 0.6 0.7 5.0 0.1 0.0 167.7 0.0 0.2 0.0 196.1 2.8 0.0 0.0 11.7 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 KCNIP2 KCHIP2 ENSG00000120049 "Potassium voltage-gated channel interacting protein 2" Q9NS61 10 101825974-101843920 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 227.4;brain: 139.6;heart muscle: 307.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 54.3;Cardiomyocytes: 135.7;Cone photoreceptor cells: 25.0;Excitatory neurons: 23.3;Horizontal cells: 48.8;Inhibitory neurons: 41.9" "Cancer enhanced" "Detected in many" "glioma: 3.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEL: 21.3;HMC-1: 12.7" "Group enriched" "Detected in all" 4 "amygdala: 96.8;basal ganglia: 234.9;cerebral cortex: 106.9;hippocampal formation: 142.6;olfactory bulb: 144.0" "Low region specificity" "Detected in all" HPA066717 Approved Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA066717: " "unprognostic (5.92e-2)" "unprognostic (2.16e-1)" "unprognostic (3.48e-3)" "unprognostic (5.77e-4)" "unprognostic (1.34e-1)" "unprognostic (1.31e-3)" "unprognostic (8.80e-2)" "unprognostic (9.11e-3)" "unprognostic (1.14e-1)" "unprognostic (5.34e-2)" "unprognostic (3.18e-2)" "unprognostic (7.20e-2)" "unprognostic (1.49e-9)" "unprognostic (9.85e-2)" "unprognostic (1.81e-1)" "unprognostic (3.27e-1)" "unprognostic (8.37e-4)" 227.4 6.8 74.5 3.5 139.6 0.9 67.1 48.8 84.5 7.4 40.5 5.0 1.8 4.1 4.1 2.5 4.9 3.1 307.5 98.8 50.6 2.8 2.3 2.5 8.1 47.5 51.6 11.5 2.4 1.7 19.7 2.9 48.1 5.2 4.7 52.6 9.9 3.5 8.0 5.9 5.3 2.6 50.3 5.7 2.7 8.5 57.1 2.3 3.5 5.4 8.3 4.8 4.4 60.8 1.7 2.6 2.5 3.2 1.0 1.1 0.6 1.2 1.0 0.6 0.9 3.6 3.4 1.6 0.9 0.8 0.7 1.7 0.9 0.4 0.6 2.4 2.0 21.3 3.0 1.9 0.9 1.4 12.7 2.6 1.7 1.0 1.4 3.7 1.0 4.7 6.3 1.8 1.0 1.2 0.8 4.0 0.8 0.7 0.6 1.0 0.2 1.4 1.0 1.1 7.4 1.2 0.8 0.6 2.4 1.5 2.2 0.9 2.3 1.3 2.0 0.6 1.2 1.7 1.9 1.7 1.4 5.3 0.2 0.0 0.0 0.7 0.0 0.5 0.1 0.9 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 74.5 139.6 48.8 84.5 98.8 50.6 47.5 51.6 48.1 50.3 57.1 60.8 0.4 0.0 0.0 8.5 2.3 0.4 0.1 0.3 0.0 54.3 0.3 0.5 135.7 0.0 0.1 1.8 25.0 0.2 0.0 0.8 0.0 0.2 6.6 0.0 0.2 1.6 0.0 0.0 23.3 0.0 0.2 5.8 0.0 0.0 0.0 0.8 0.4 0.1 2.2 48.8 41.9 0.4 0.0 0.6 0.8 5.2 1.8 0.3 0.0 1.0 0.5 8.3 0.0 5.5 3.7 0.3 0.2 0.7 0.3 0.1 0.5 0.1 0.2 4.7 0.0 0.1 1.3 2.5 5.5 0.5 0.0 0.3 0.1 0.5 0.3 0.1 KCNIP3 "CSEN, DREAM, KCHIP3" ENSG00000115041 "Potassium voltage-gated channel interacting protein 3" Q9Y2W7 2 95297327-95386077 "Predicted intracellular proteins, Transporters" "Apoptosis, Ion transport, Potassium transport, Transcription, Transcription regulation, Transport" "Ion channel, Potassium channel, Repressor, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 39.0;Leydig cells: 25.4;Oligodendrocyte precursor cells: 54.8;Peritubular cells: 42.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 13.8;BJ hTERT+: 18.0;hTERT-RPE1: 23.2;RPTEC TERT1: 35.2;U-138 MG: 16.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066717, HPA069797" Enhanced Approved Vesicles "Intracellular and membrane" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA066717: , HPA069797: AB_2686199" "unprognostic (1.05e-2)" "unprognostic (5.76e-2)" "unprognostic (3.33e-3)" "prognostic unfavorable (1.58e-5)" "unprognostic (2.67e-1)" "unprognostic (6.73e-2)" "unprognostic (2.23e-1)" "unprognostic (2.96e-1)" "unprognostic (2.73e-1)" "unprognostic (7.42e-2)" "unprognostic (2.32e-1)" "unprognostic (4.09e-1)" "unprognostic (1.44e-3)" "unprognostic (8.90e-2)" "unprognostic (6.51e-2)" "unprognostic (7.33e-2)" "unprognostic (1.04e-1)" 6.7 1.5 21.8 0.8 20.0 0.0 5.4 15.2 31.2 10.7 12.2 9.8 1.2 10.6 3.6 2.4 10.1 1.5 6.0 22.1 16.8 8.4 2.0 2.4 0.4 15.4 17.2 10.1 2.4 27.0 6.4 5.3 15.2 9.3 0.9 0.5 5.6 14.7 1.5 6.0 3.7 5.1 15.3 2.6 5.5 12.2 18.0 24.4 19.7 1.8 0.5 9.0 10.6 19.3 13.8 0.0 0.8 6.1 5.3 4.2 0.0 6.3 18.0 10.1 9.3 0.0 0.0 0.0 0.6 8.3 5.5 0.2 4.0 1.1 4.3 0.0 1.4 0.0 1.8 0.0 2.2 0.0 0.0 2.9 3.6 2.2 10.0 23.2 0.0 1.0 0.0 0.0 0.8 8.0 0.1 0.0 0.1 0.0 3.7 0.0 0.0 0.0 35.2 0.0 0.7 0.2 0.3 0.3 6.8 0.0 0.3 0.1 0.3 16.3 3.8 0.0 4.9 0.0 0.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.8 20.0 15.2 31.2 22.1 16.8 15.4 17.2 15.2 15.3 18.0 19.3 0.4 0.0 1.1 13.4 0.5 0.4 0.8 0.0 1.2 8.1 1.0 1.0 1.6 0.0 0.0 1.8 0.0 0.0 0.0 0.2 7.9 0.2 0.6 0.3 3.7 1.0 4.2 0.0 39.0 0.0 0.1 3.5 0.0 0.3 0.0 7.5 0.0 0.5 0.1 0.0 5.1 0.1 0.0 0.0 0.4 1.3 25.4 0.1 7.2 1.9 0.6 0.5 0.0 54.8 3.0 0.2 0.0 42.9 0.0 0.5 1.0 1.5 0.0 0.0 0.0 8.3 3.7 0.1 0.9 0.2 0.9 0.0 0.0 1.5 0.3 0.1 KCNIP4 "CALP, KCHIP4, MGC44947" ENSG00000185774 "Potassium voltage-gated channel interacting protein 4" Q6PIL6 4 20728606-21948772 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.5;retina: 18.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 9816.7;Inhibitory neurons: 1982.4;Oligodendrocyte precursor cells: 5175.8" "Cancer enhanced" "Detected in some" "glioma: 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "RPTEC TERT1: 6.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022862, HPA066717" Supported Approved Vesicles NA NA "Cluster 58: Brain - Synaptic function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA022862: AB_1852654, HPA066717: " "unprognostic (8.08e-2)" "unprognostic (1.05e-1)" "unprognostic (7.36e-2)" "unprognostic (4.14e-2)" "unprognostic (9.26e-2)" "unprognostic (1.49e-1)" "unprognostic (2.53e-1)" "unprognostic (2.99e-2)" "unprognostic (1.18e-1)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (2.13e-1)" "unprognostic (3.11e-1)" "unprognostic (1.03e-2)" "unprognostic (2.69e-1)" "unprognostic (4.59e-2)" "unprognostic (2.10e-2)" 0.6 2.2 11.9 1.3 16.4 0.0 0.6 13.8 24.5 11.0 0.0 6.9 1.2 6.2 0.6 4.0 2.5 1.1 0.5 17.8 12.8 8.2 0.2 0.5 0.0 7.0 7.9 1.3 0.5 0.0 4.2 1.0 13.7 0.5 4.1 18.1 0.5 0.3 0.3 0.5 3.8 6.0 4.3 0.3 0.8 0.4 9.0 0.0 6.4 0.0 0.0 1.0 1.5 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.3 0.1 0.0 0.2 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.4 0.4 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 16.4 13.8 24.5 17.8 12.8 7.0 7.9 13.7 4.3 9.0 10.6 0.0 0.0 0.0 148.2 0.1 0.0 0.0 0.0 0.0 33.0 0.1 0.0 0.5 0.0 0.0 14.7 0.0 0.1 0.0 0.3 62.6 0.1 9.8 0.2 2.1 1.6 0.0 0.0 9816.7 0.0 0.0 3.1 0.0 0.2 0.0 12.3 1.1 0.2 0.2 0.0 1982.4 0.6 0.0 0.0 0.0 4.2 0.0 0.5 3.6 119.9 0.6 45.9 0.0 5175.8 91.4 0.0 7.8 0.0 0.0 0.0 0.4 15.2 0.0 12.6 0.0 0.2 0.4 0.1 0.7 0.1 0.1 0.1 0.1 14.5 0.7 0.1 KCNJ15 "IRKK, Kir1.3, Kir4.2" ENSG00000157551 "Potassium inwardly rectifying channel subfamily J member 15" Q99712 21 38155549-38307357 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 241.6;thyroid gland: 129.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 60.9;Alveolar cells type 2: 197.9;Cholangiocytes: 88.6;Proximal tubular cells: 236.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 29.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 20 "neutrophil: 395.3" "Lineage enriched" "Detected in many" 20 "granulocytes: 395.3" "Cell line enhanced" "Detected in many" "ASC TERT1: 68.7;GAMG: 103.6;HBEC3-KT: 69.6;RPTEC TERT1: 67.5;RT4: 80.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA016702 Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Vesicles, Cytosol" "HPA016702: AB_1855560" "unprognostic (6.34e-2)" "unprognostic (5.04e-2)" "unprognostic (7.92e-2)" "unprognostic (2.07e-3)" "unprognostic (1.21e-1)" "unprognostic (3.54e-3)" "unprognostic (2.72e-3)" "unprognostic (3.03e-2)" "unprognostic (6.79e-2)" "unprognostic (2.89e-3)" "unprognostic (3.77e-2)" "unprognostic (1.95e-2)" "prognostic favorable (4.09e-10)" "unprognostic (9.46e-3)" "unprognostic (1.82e-1)" "unprognostic (5.27e-2)" "prognostic favorable (1.95e-4)" 8.7 0.5 0.8 20.7 0.7 14.1 2.8 0.9 6.7 12.7 0.5 0.9 1.5 0.5 11.0 8.5 1.2 30.4 0.8 0.8 0.6 241.6 2.8 42.2 1.2 0.9 0.6 0.3 57.8 0.7 0.4 4.6 1.8 2.6 0.4 0.5 25.5 14.6 0.5 3.0 0.7 2.4 0.3 11.7 40.5 1.8 5.4 1.9 129.5 3.0 1.9 25.1 8.1 1.1 1.6 0.0 0.3 0.6 13.7 68.7 0.6 1.0 4.8 0.0 0.0 0.0 0.6 0.2 0.0 7.5 103.6 23.5 0.0 69.6 0.6 0.0 0.0 0.0 0.5 0.3 0.0 0.2 0.1 21.0 7.2 17.8 3.8 1.5 3.2 0.1 0.2 0.7 31.6 0.0 0.1 0.2 0.0 0.1 0.7 1.5 0.3 0.7 67.5 80.2 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.5 0.0 1.5 0.4 3.5 0.2 1.7 0.4 0.1 5.6 4.3 0.4 0.3 19.3 0.1 0.0 0.8 0.0 0.0 0.1 0.0 1.2 0.0 0.2 0.3 395.3 0.0 0.0 0.4 0.0 4.6 0.8 0.7 0.9 6.7 0.8 0.6 0.9 0.6 1.8 0.3 5.4 1.1 2.9 60.9 197.9 0.0 1.1 2.8 10.4 20.7 13.6 0.0 0.5 0.0 1.6 88.6 33.1 31.3 0.0 0.1 0.0 0.0 17.6 27.8 1.9 0.0 0.0 4.6 0.0 0.0 0.3 8.6 0.8 1.5 15.8 0.1 6.3 0.0 0.7 0.4 0.4 0.0 0.1 0.0 2.0 2.9 3.0 2.2 0.6 5.9 1.8 0.0 2.1 0.0 0.0 0.0 0.1 44.7 0.0 0.0 0.1 0.7 0.0 236.9 7.0 0.0 0.0 1.5 0.8 1.1 1.1 16.8 1.6 0.1 1.7 0.1 0.0 9.0 KCNJ16 "BIR9, Kir5.1" ENSG00000153822 "Potassium inwardly rectifying channel subfamily J member 16" Q9NPI9 17 70053429-70135608 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 196.1;parathyroid gland: 269.2;thyroid gland: 139.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 54.3;Collecting duct cells: 244.6;Distal tubular cells: 41.1;Oligodendrocyte precursor cells: 54.8;Proximal tubular cells: 95.2" "Group enriched" "Detected in many" 10 "renal cancer: 37.2;thyroid cancer: 80.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.6" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.6" "Cell line enriched" "Detected in some" 22 "RPTEC TERT1: 279.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059563 Approved Uncertain Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA059563: AB_2684065" "unprognostic (2.81e-3)" "unprognostic (2.10e-1)" "unprognostic (6.06e-2)" "unprognostic (1.20e-3)" "unprognostic (1.16e-1)" "unprognostic (7.53e-2)" "unprognostic (4.38e-4)" "unprognostic (1.02e-1)" "unprognostic (1.23e-1)" "unprognostic (1.52e-2)" "unprognostic (3.35e-1)" "unprognostic (1.34e-1)" "prognostic favorable (9.61e-7)" "unprognostic (2.74e-1)" "unprognostic (1.39e-1)" "prognostic favorable (6.58e-4)" "unprognostic (3.88e-1)" 0.3 0.4 10.0 0.4 14.0 0.6 3.8 22.7 11.6 0.1 2.3 0.6 0.7 0.5 15.9 0.3 5.1 18.8 0.6 6.8 39.5 196.1 1.3 0.9 0.8 39.7 37.6 0.2 44.2 269.2 1.0 0.9 25.7 0.2 0.2 1.2 11.8 21.7 0.3 0.8 2.5 0.0 29.9 1.5 23.4 1.7 27.3 0.2 139.4 0.0 0.1 0.0 0.0 20.8 0.1 0.4 0.2 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.6 0.0 1.2 0.5 0.0 0.2 0.0 0.0 0.0 0.2 1.2 0.8 0.3 0.3 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 1.1 0.2 0.0 0.0 0.0 0.3 0.6 0.1 0.0 12.7 0.0 0.0 279.8 0.2 0.3 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.4 0.0 0.3 0.1 0.1 0.0 0.2 0.8 0.2 0.0 0.1 0.0 0.0 0.2 0.3 0.0 0.3 0.3 0.3 0.1 0.0 0.3 0.2 0.2 1.6 0.3 0.0 0.1 0.3 0.1 10.0 14.0 22.7 11.6 6.8 39.5 39.7 37.6 25.7 29.9 27.3 20.8 0.1 0.0 0.0 12.1 0.0 0.0 0.0 2.7 0.0 0.0 2.3 1.1 0.4 54.3 2.6 244.6 0.0 0.0 0.0 0.0 41.1 12.4 0.0 2.8 0.1 0.0 0.0 0.0 1.0 1.4 0.0 0.3 3.1 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 54.8 0.1 6.0 0.0 0.0 0.0 0.0 1.0 95.2 9.8 0.0 0.0 0.2 0.3 0.2 0.6 0.0 0.0 0.0 0.6 0.2 0.0 0.0 KCNK1 "DPK, K2p1.1, TWIK-1" ENSG00000135750 "Potassium two pore domain channel subfamily K member 1" O00180 1 233614106-233672514 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 157.8;Horizontal cells: 200.2;Prostatic glandular cells: 222.9;Urothelial cells: 371.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 69 "plasmacytoid DC: 6.9" "Lineage enriched" "Detected in single" 69 "dendritic cells: 6.9" "Cell line enhanced" "Detected in many" "HeLa: 64.7;SCLC-21H: 62.5;U-266/70: 137.3;U-266/84: 134.7" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 117.0" "HPA016049, CAB022588" Approved Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 45: Intestine - Brush border" "Cluster 29: U-266 - Adaptive immune response" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "CAB022588: , HPA016049: AB_1855571" "unprognostic (7.06e-3)" "unprognostic (1.76e-1)" "unprognostic (4.64e-2)" "unprognostic (7.46e-2)" "unprognostic (9.15e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.84e-4)" "unprognostic (4.32e-2)" "unprognostic (6.15e-2)" "unprognostic (1.34e-2)" "prognostic unfavorable (7.29e-4)" "unprognostic (1.10e-1)" "prognostic unfavorable (8.69e-8)" "unprognostic (1.62e-1)" "unprognostic (2.76e-1)" "unprognostic (1.77e-1)" "unprognostic (1.97e-1)" 3.9 4.1 17.7 2.9 19.8 0.3 5.7 58.0 28.4 7.8 50.4 15.7 16.9 6.1 30.9 20.9 10.9 12.1 41.0 24.3 13.7 9.2 12.1 4.4 1.0 23.5 17.8 7.3 5.5 16.2 22.2 6.8 24.1 6.4 13.9 18.5 15.1 11.3 0.4 13.3 12.6 3.8 15.4 0.9 38.1 0.9 16.3 0.5 7.2 0.9 4.4 11.5 14.4 21.3 33.2 18.3 0.1 0.0 0.0 0.0 50.2 8.8 0.0 0.0 0.0 0.0 52.9 0.0 20.7 6.8 7.3 47.1 8.9 15.2 0.0 0.1 15.8 0.0 64.7 0.0 0.5 0.0 1.8 3.9 17.0 0.0 12.4 1.1 0.2 17.7 7.9 15.0 0.0 12.6 12.2 0.1 10.9 38.5 41.0 0.0 2.7 3.7 16.0 28.4 62.5 11.8 33.5 14.3 0.0 1.0 4.1 0.1 0.0 0.1 25.8 0.0 1.0 137.3 134.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 17.7 19.8 58.0 28.4 24.3 13.7 23.5 17.8 24.1 15.4 16.3 21.3 0.4 9.6 22.9 5.9 0.6 63.3 136.7 32.6 3.4 2.9 23.0 6.0 54.7 12.8 44.6 18.4 4.2 0.5 3.0 91.0 1.9 29.2 1.1 52.7 26.4 3.5 29.3 0.0 157.8 48.3 14.0 31.2 50.4 89.3 0.0 15.0 0.0 8.9 0.6 200.2 61.0 56.3 24.4 0.3 4.4 0.2 1.5 1.0 10.6 12.2 0.0 72.6 0.0 36.2 73.2 96.3 82.4 0.0 0.2 222.9 10.6 8.8 42.9 5.1 0.0 2.3 6.9 0.6 3.2 19.1 47.6 0.8 1.4 0.5 31.2 371.6 KCNQ5 Kv7.5 ENSG00000185760 "Potassium voltage-gated channel subfamily Q member 5" Q9NR82 6 72621792-73198853 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 28.3;skeletal muscle: 21.1;tongue: 12.2" "Group enriched" "Detected in some" 30 "Excitatory neurons: 2136.7;Inhibitory neurons: 862.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 28.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 34.9;HEL: 23.2;HL-60: 31.5;U-251 MG: 23.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016655 Approved Approved Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA016655: AB_1855557" "unprognostic (4.91e-2)" "unprognostic (1.42e-1)" "unprognostic (4.96e-2)" "unprognostic (3.78e-2)" "unprognostic (2.69e-1)" "unprognostic (2.18e-2)" "unprognostic (3.57e-2)" "unprognostic (1.43e-1)" "unprognostic (6.09e-2)" "unprognostic (8.55e-2)" "unprognostic (7.96e-2)" "unprognostic (1.05e-1)" "unprognostic (6.77e-2)" "unprognostic (1.08e-2)" "unprognostic (2.62e-1)" "unprognostic (8.16e-2)" "unprognostic (1.39e-3)" 0.1 1.6 1.2 1.3 7.5 5.1 0.4 0.0 28.3 0.4 0.0 0.4 0.2 0.1 0.0 0.9 0.3 0.3 0.2 4.3 0.0 0.1 0.2 0.3 2.2 17.4 1.0 0.1 0.1 0.0 0.2 0.4 19.4 1.3 0.3 0.2 1.2 0.9 21.1 0.1 0.7 0.3 0.0 1.1 0.3 1.2 0.0 1.7 4.7 12.2 2.0 0.9 0.6 4.6 4.4 1.1 0.0 0.2 0.0 1.5 0.0 34.9 5.2 5.1 4.3 0.0 0.0 21.2 0.0 11.9 0.4 0.7 0.1 2.1 6.1 0.3 7.2 23.2 0.1 0.0 0.9 31.5 0.0 0.3 0.8 14.5 14.9 3.3 0.0 0.0 1.4 14.2 10.2 0.1 0.0 13.5 1.3 0.0 7.1 0.0 1.1 14.4 1.9 0.0 5.8 2.7 0.0 0.1 13.7 0.2 4.3 2.3 0.0 21.0 9.2 0.1 23.4 14.8 0.4 9.3 0.2 14.9 1.2 0.3 0.0 0.0 0.0 0.0 0.2 0.9 0.1 0.4 0.1 0.3 0.3 0.3 0.0 0.6 0.0 0.0 0.0 0.0 1.2 7.5 0.0 28.3 4.3 0.0 17.4 1.0 19.4 0.0 0.0 4.6 0.0 0.0 0.0 38.8 7.6 0.3 3.6 0.7 5.2 0.3 0.4 0.5 3.6 0.0 0.1 0.0 0.0 0.1 2.6 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 5.5 2136.7 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 862.4 0.0 0.0 0.0 1.5 1.6 0.0 0.2 1.8 49.6 0.0 0.1 1.0 30.2 26.7 0.0 0.0 0.0 7.6 5.7 0.0 0.0 0.0 0.2 0.0 6.0 0.8 0.5 0.5 0.8 0.3 0.3 2.8 0.0 0.0 0.7 KCNRG ENSG00000198553 "Potassium channel regulator" Q8N5I3 13 50015254-50020922 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "fallopian tube: 35.7" "Cell type enhanced" "Detected in some" "Early spermatids: 19.4;Endometrial ciliated cells: 46.0;Late spermatids: 12.6;Respiratory ciliated cells: 88.6" "Cancer enhanced" "Detected in single" "endometrial cancer: 1.6" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "JURKAT: 3.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001027 Uncertain Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA001027: " "unprognostic (1.85e-3)" "unprognostic (1.66e-2)" "unprognostic (1.08e-2)" "prognostic favorable (2.61e-5)" "unprognostic (3.15e-1)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (5.39e-3)" "unprognostic (1.26e-1)" "unprognostic (1.09e-1)" "unprognostic (1.71e-1)" "unprognostic (5.91e-1)" "unprognostic (1.65e-2)" "unprognostic (4.98e-2)" "unprognostic (4.69e-2)" "unprognostic (1.52e-1)" "unprognostic (9.16e-2)" 0.6 0.3 0.5 0.6 2.3 1.9 0.8 3.2 1.6 1.4 0.1 0.6 0.5 1.3 0.5 0.8 35.7 0.4 0.6 0.5 1.2 0.8 0.4 3.1 0.6 2.1 0.9 0.5 0.4 1.1 0.5 0.2 1.3 0.6 0.8 0.8 0.5 0.4 0.6 0.9 0.6 0.5 0.6 0.6 0.5 2.0 1.5 0.6 0.5 0.5 0.6 0.7 0.5 3.5 0.4 0.3 1.1 0.4 0.4 0.5 0.2 0.0 0.9 0.8 0.0 1.3 0.4 0.8 0.2 1.1 0.5 0.5 0.8 0.3 0.6 0.6 0.5 1.7 0.5 0.7 1.0 1.5 0.4 0.6 0.8 0.5 1.4 0.7 1.6 3.1 0.7 0.1 1.0 0.5 1.6 1.5 0.9 1.0 0.6 1.0 0.0 0.0 0.7 1.0 1.0 2.2 0.3 0.7 0.8 0.6 0.6 0.4 0.5 0.7 0.3 0.4 0.3 0.1 0.2 0.9 0.2 0.5 0.2 1.0 0.3 0.2 0.1 0.3 0.2 0.4 0.1 0.3 0.3 0.6 0.2 0.2 1.2 0.4 0.2 0.3 0.4 0.1 0.5 2.3 3.2 1.6 0.5 1.2 2.1 0.9 1.3 0.6 1.5 3.5 1.1 0.0 2.7 0.7 0.9 0.1 0.9 3.8 0.0 1.0 0.6 0.9 0.5 0.0 6.2 0.0 2.1 0.8 0.5 0.8 0.0 0.5 19.4 46.0 1.0 0.8 4.2 0.0 0.7 1.4 0.5 0.8 0.0 1.0 0.0 0.5 0.0 0.3 0.5 3.3 0.7 0.9 0.0 0.0 0.3 12.6 0.6 1.3 0.0 0.0 1.3 0.7 0.0 1.0 0.5 0.6 0.3 0.7 0.0 0.9 0.8 2.1 88.6 1.2 0.0 1.4 1.5 11.4 1.5 0.0 0.1 0.7 0.5 0.5 0.7 1.3 KCNT2 "KCa4.2, SLICK, SLO2.1" ENSG00000162687 "Potassium sodium-activated channel subfamily T member 2" Q6UVM3 1 196225779-196609225 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 3.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 220.2;Inhibitory neurons: 240.5;Oligodendrocyte precursor cells: 310.7" "Cancer enhanced" "Detected in some" "renal cancer: 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 3.2;hTERT-RPE1: 9.0;SCLC-21H: 7.5;SH-SY5Y: 5.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051218 Uncertain Approved Vesicles NA NA "Cluster 15: Liver - Metabolism" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA051218: AB_2681392" "unprognostic (5.06e-2)" "unprognostic (2.94e-2)" "unprognostic (8.01e-2)" "unprognostic (5.10e-6)" "unprognostic (1.22e-3)" "unprognostic (1.30e-2)" "unprognostic (1.07e-1)" "unprognostic (3.03e-2)" "unprognostic (5.90e-2)" "unprognostic (2.18e-1)" "unprognostic (9.56e-3)" "unprognostic (2.61e-1)" "prognostic unfavorable (1.67e-5)" "unprognostic (3.30e-4)" "unprognostic (2.95e-2)" "unprognostic (4.75e-1)" "unprognostic (1.72e-3)" 1.0 0.6 0.9 0.1 2.0 0.0 0.4 0.0 2.0 0.4 0.3 0.5 0.2 0.3 0.4 1.0 0.5 1.4 1.8 2.5 3.3 0.3 2.8 1.8 0.1 0.0 0.2 3.8 0.1 0.0 0.9 0.2 0.0 1.0 0.5 0.1 0.5 0.6 0.1 0.3 0.4 0.5 0.6 0.2 0.5 1.1 1.0 0.1 1.1 0.8 0.1 0.8 0.4 0.5 0.0 0.1 1.8 0.0 0.2 0.2 0.0 0.0 1.0 0.1 1.8 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.9 0.0 3.2 0.0 0.0 1.2 0.0 0.4 0.1 9.0 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 2.4 0.0 0.1 0.0 0.1 0.0 0.0 0.5 7.5 5.6 0.0 0.0 0.1 1.9 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.0 0.0 2.0 2.5 3.3 0.0 0.2 0.0 0.6 1.0 0.5 0.8 41.7 1.1 6.8 0.0 0.4 0.2 0.0 0.6 0.0 0.0 0.1 1.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.2 0.8 0.0 0.0 220.2 0.0 0.0 9.3 0.0 0.0 0.0 6.1 2.5 6.2 0.0 0.0 240.5 0.0 0.0 0.0 0.7 3.3 6.5 0.0 1.8 58.1 0.0 0.0 0.0 310.7 6.1 0.0 0.0 4.9 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.4 4.0 0.6 0.2 0.0 0.0 0.0 0.0 3.9 0.0 0.2 KCTD14 MGC2376 ENSG00000151364 "Potassium channel tetramerization domain containing 14" Q9BQ13 11 78015715-78046191 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 13.7;Breast myoepithelial cells: 12.8;Exocrine glandular cells: 17.1;Gastric mucus-secreting cells: 14.3;Intestinal goblet cells: 20.8;Prostatic glandular cells: 14.3;Proximal tubular cells: 15.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 26.1;Hep G2: 29.0;RPTEC TERT1: 45.9;U-2 OS: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041118, HPA042181" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 30: Mammary glandular cells - Lactation" Nucleoplasm "Vesicles, Cytosol" "HPA041118: AB_10963117, HPA042181: AB_10968059" "unprognostic (7.37e-3)" "unprognostic (4.27e-2)" "unprognostic (7.03e-2)" "unprognostic (6.93e-2)" "unprognostic (1.59e-2)" "unprognostic (2.28e-2)" "unprognostic (2.04e-3)" "unprognostic (3.26e-1)" "prognostic unfavorable (3.96e-5)" "prognostic favorable (8.01e-4)" "prognostic unfavorable (1.05e-4)" "unprognostic (3.19e-1)" "prognostic favorable (6.92e-5)" "unprognostic (2.42e-2)" "unprognostic (2.05e-1)" "prognostic favorable (5.93e-4)" "unprognostic (1.63e-1)" 3.4 23.1 2.0 1.6 2.0 0.1 20.4 5.1 2.9 10.4 3.2 8.1 4.9 3.4 14.3 1.5 11.7 6.7 0.6 2.1 2.1 11.5 10.3 8.2 0.3 1.9 2.3 0.8 27.2 8.3 2.5 1.3 2.2 7.0 11.9 1.6 28.7 19.1 0.2 1.9 5.2 2.1 1.6 0.6 20.8 0.6 2.5 1.3 15.9 0.6 0.5 2.3 1.4 1.7 0.0 3.5 0.6 0.5 1.3 0.8 3.5 1.8 1.6 3.4 8.4 13.5 8.8 0.1 9.3 1.1 0.4 1.0 0.6 26.1 8.9 0.5 13.2 0.0 3.0 29.0 4.9 0.2 0.1 4.0 0.7 13.9 11.0 2.5 1.0 0.2 0.3 0.1 1.4 0.2 0.3 0.8 6.5 0.5 0.5 0.4 0.0 0.0 45.9 3.5 2.3 0.2 0.0 0.2 4.5 0.8 1.4 1.1 0.8 0.2 20.2 0.7 0.4 0.3 0.2 0.2 0.2 0.2 3.7 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.3 0.2 0.0 0.1 0.3 0.0 0.2 0.2 0.2 0.0 0.0 2.0 2.0 5.1 2.9 2.1 2.1 1.9 2.3 2.2 1.6 2.5 1.7 0.6 3.2 10.8 0.0 0.2 0.4 12.2 2.0 2.8 0.4 13.7 12.8 0.0 1.5 4.1 5.5 0.0 0.6 0.3 5.2 3.9 2.6 0.3 2.7 2.0 0.9 4.8 0.0 0.0 17.1 1.3 1.1 14.3 3.7 1.3 0.5 0.0 4.8 0.2 0.0 0.0 20.8 0.0 0.0 0.0 0.0 3.4 0.4 1.8 0.0 0.1 2.1 0.0 0.0 0.0 10.5 6.6 5.3 0.0 14.3 2.2 15.1 0.1 0.0 0.0 0.0 1.8 0.2 0.3 0.7 0.1 0.7 0.3 0.7 8.5 7.4 KCTD8 ENSG00000183783 "Potassium channel tetramerization domain containing 8" Q6ZWB6 4 44173903-44448809 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 26.0;retina: 6.8" "Group enriched" "Detected in some" 4 "Astrocytes: 169.4;Excitatory neurons: 223.7;Inhibitory neurons: 445.3;Oligodendrocyte precursor cells: 322.7;Oligodendrocytes: 610.8" "Cancer enhanced" "Detected in some" "glioma: 0.9;thyroid cancer: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 2.2;NTERA-2: 1.5;SCLC-21H: 5.7;U-2 OS: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA031562 Enhanced Approved Vesicles NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA031562: AB_10602609" "unprognostic (1.49e-2)" "unprognostic (7.70e-3)" "unprognostic (1.53e-1)" "unprognostic (4.15e-1)" "unprognostic (1.77e-2)" "unprognostic (1.48e-1)" "unprognostic (7.85e-2)" "unprognostic (2.62e-3)" "unprognostic (1.33e-1)" "unprognostic (4.58e-3)" "unprognostic (2.57e-3)" "unprognostic (8.72e-2)" "unprognostic (3.55e-2)" "unprognostic (2.44e-1)" 1.5 0.2 5.4 0.0 9.6 0.0 0.0 26.0 7.0 1.0 3.6 0.9 0.0 1.4 0.2 0.1 0.2 0.3 0.2 6.4 11.5 0.8 0.0 0.1 0.0 9.2 12.7 1.5 0.6 1.0 0.0 0.0 10.2 0.4 0.1 6.8 0.4 0.9 1.5 0.1 0.1 0.5 14.6 0.0 1.5 1.3 8.2 0.0 3.0 1.1 0.0 0.1 0.3 16.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.9 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 9.6 26.0 7.0 6.4 11.5 9.2 12.7 10.2 14.6 8.2 16.3 0.1 0.0 0.0 169.4 0.0 0.0 0.6 0.0 1.8 2.6 1.3 0.3 0.3 4.3 0.0 3.7 4.2 0.0 0.0 0.0 0.0 0.1 0.5 0.1 3.5 1.0 0.0 0.0 223.7 0.0 0.0 1.0 0.0 0.1 0.0 2.0 0.4 0.0 0.1 0.0 445.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 71.2 0.0 4.4 0.0 322.7 610.8 0.2 0.0 0.0 0.0 1.2 0.0 1.9 0.0 17.1 0.0 1.7 0.2 0.1 1.6 1.0 0.0 0.1 0.0 10.0 0.0 0.1 KDELR1 "ERD2, ERD2.1, HDEL" ENSG00000105438 "KDEL endoplasmic reticulum protein retention receptor 1" P24390 19 48382575-48391551 "Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 605.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 856.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB017455 Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "Vesicles, Cytosol" "CAB017455: AB_10615208" "unprognostic (3.10e-2)" "unprognostic (4.17e-2)" "unprognostic (1.64e-1)" "unprognostic (1.87e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (3.49e-4)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.35e-2)" "unprognostic (2.26e-1)" "unprognostic (1.71e-1)" "unprognostic (1.51e-1)" "unprognostic (7.55e-2)" "unprognostic (4.97e-2)" "unprognostic (3.81e-1)" "unprognostic (2.74e-1)" "unprognostic (3.06e-1)" "unprognostic (1.68e-2)" 109.3 124.4 58.0 61.7 56.5 45.8 106.6 54.5 59.7 132.5 78.1 120.3 132.5 110.0 117.3 107.3 112.2 100.9 96.6 56.1 62.5 119.5 127.2 101.4 53.3 61.1 59.1 165.8 138.9 191.7 116.2 128.7 59.0 102.5 128.5 39.0 137.7 105.0 76.8 103.8 114.5 100.6 56.2 79.5 120.1 93.7 62.9 51.6 121.8 58.4 73.2 102.5 102.4 58.0 216.2 305.3 173.1 184.7 379.7 440.6 126.5 207.4 363.9 247.0 281.0 202.3 238.7 89.1 132.6 456.4 154.4 187.6 211.1 222.2 234.0 72.7 224.5 74.4 99.4 382.2 329.6 84.1 133.4 419.6 268.0 168.5 178.5 387.4 233.0 75.3 131.7 160.9 333.1 173.6 79.4 856.7 126.3 426.8 122.5 112.1 103.4 141.0 316.2 176.3 172.9 134.5 182.1 160.6 113.1 196.7 126.6 102.1 182.6 173.4 142.6 145.3 179.3 451.1 382.0 60.2 110.1 112.4 181.1 10.8 41.0 12.6 18.1 34.7 20.8 17.0 17.6 19.7 30.6 14.3 14.3 16.1 9.9 20.2 30.2 45.4 20.4 18.2 58.0 56.5 54.5 59.7 56.1 62.5 61.1 59.1 59.0 56.2 62.9 58.0 150.8 35.3 54.2 8.5 82.2 75.3 130.6 147.1 124.7 39.4 141.0 154.4 28.8 98.7 110.9 93.8 6.2 231.7 59.5 153.0 56.7 224.1 6.2 72.0 188.8 111.4 145.0 56.8 8.7 169.0 605.5 161.0 120.3 166.3 62.7 149.2 102.8 79.6 180.0 40.4 12.7 379.6 93.6 107.6 73.5 14.2 163.5 103.1 92.5 8.4 102.3 89.8 35.0 10.6 10.6 190.3 199.8 132.0 365.9 161.2 213.8 149.6 49.2 28.1 85.5 87.9 131.6 41.8 69.1 127.7 70.2 387.7 55.4 191.3 202.9 157.6 KDR "CD309, FLK1, VEGFR, VEGFR2" ENSG00000128052 "Kinase insert domain receptor" P35968 4 55078481-55125595 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Adipocytes: 157.8;Endothelial cells: 143.8;Hepatic stellate cells: 158.1;Muller glia cells: 206.6" "Cancer enhanced" "Detected in all" "renal cancer: 27.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HUVEC TERT2: 74.8;TIME: 83.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004028, HPA073577" Enhanced Approved "Nuclear membrane,Vesicles" "Intracellular and membrane" NA NA 11000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Nuclear membrane" "CAB004028: AB_2212507, HPA073577: " "unprognostic (1.61e-1)" "unprognostic (2.03e-1)" "unprognostic (9.65e-2)" "unprognostic (1.97e-1)" "unprognostic (9.63e-2)" "unprognostic (1.22e-2)" "unprognostic (1.78e-3)" "unprognostic (2.59e-2)" "unprognostic (1.19e-2)" "unprognostic (1.10e-1)" "unprognostic (8.79e-3)" "unprognostic (1.34e-1)" "prognostic unfavorable (7.26e-4)" "unprognostic (4.00e-2)" "unprognostic (2.30e-1)" "unprognostic (3.22e-1)" "unprognostic (1.86e-1)" 41.6 11.7 2.7 4.3 3.8 0.0 26.1 2.8 4.1 14.8 10.4 6.3 2.2 39.5 2.9 4.0 17.9 5.6 20.6 2.1 2.8 15.7 9.2 23.5 2.8 3.2 3.6 5.2 6.2 8.6 11.0 30.9 3.5 11.7 1.0 16.4 5.3 10.0 6.5 5.9 7.5 7.5 3.3 4.4 8.4 1.8 4.5 1.0 34.4 4.6 1.0 8.6 7.5 3.4 0.0 0.0 4.4 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 8.5 0.0 0.0 0.9 0.0 0.0 0.4 0.2 74.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.9 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 83.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.8 2.8 4.1 2.1 2.8 3.2 3.6 3.5 3.3 4.5 3.4 157.8 0.0 4.9 0.0 1.4 2.5 0.5 0.1 1.8 11.7 1.3 2.5 9.4 1.5 18.4 0.0 0.0 0.1 0.8 0.0 0.0 0.5 0.8 0.4 2.6 143.8 0.0 2.7 0.1 0.0 0.1 8.3 0.0 0.8 2.5 0.0 158.1 3.3 0.4 0.0 1.3 0.0 0.0 10.6 2.1 0.9 0.0 1.2 7.2 7.5 0.0 206.6 0.0 0.0 6.1 0.5 0.0 0.4 1.3 0.5 0.0 0.0 3.9 7.9 0.0 0.9 7.5 0.3 0.9 0.8 2.7 0.1 0.6 1.6 0.0 1.4 KHK ENSG00000138030 Ketohexokinase P50053 2 27086747-27100762 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 14 "intestine: 121.2;kidney: 104.4;liver: 180.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 428.5;Proximal enterocytes: 1858.7;Proximal tubular cells: 1019.7" "Group enriched" "Detected in all" 7 "liver cancer: 62.2;renal cancer: 32.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 32.8;Hep G2: 48.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007040 Enhanced Approved Vesicles,Cytosol NA NA 620000 "Cluster 39: Non-specific - mRNA processing" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol Vesicles "HPA007040: AB_1079185" "unprognostic (8.44e-2)" "unprognostic (1.49e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (7.62e-8)" "unprognostic (2.25e-1)" "unprognostic (1.21e-1)" "unprognostic (3.08e-2)" "unprognostic (3.13e-2)" "unprognostic (1.67e-2)" "unprognostic (2.50e-2)" "unprognostic (3.01e-2)" "unprognostic (1.30e-1)" "unprognostic (1.68e-2)" "unprognostic (2.56e-3)" "unprognostic (2.32e-1)" "unprognostic (2.44e-1)" "unprognostic (1.02e-2)" 2.2 4.6 4.2 3.0 4.3 1.7 2.0 7.1 5.9 2.6 1.2 4.2 112.4 3.8 0.6 2.4 4.3 1.3 1.4 4.8 3.9 104.4 180.5 1.6 1.9 5.4 4.0 3.6 9.4 2.6 1.4 0.5 5.5 1.6 1.2 1.5 4.4 1.4 3.8 2.4 121.2 1.9 3.6 2.0 2.9 3.2 3.8 0.7 1.1 2.0 1.2 1.8 2.3 4.7 25.0 18.5 2.8 11.0 2.0 0.5 2.5 1.7 1.1 2.3 1.4 9.0 5.3 3.7 5.8 0.1 2.6 10.7 9.4 3.1 0.8 8.8 17.2 32.8 5.2 48.0 1.1 4.6 3.7 0.1 1.3 2.7 0.2 1.2 2.1 5.1 5.9 6.1 0.2 16.0 5.4 3.6 4.0 22.3 7.2 18.9 1.4 20.9 2.7 3.0 10.2 15.8 3.6 6.2 6.9 1.0 2.7 2.0 1.9 0.7 3.6 1.6 6.5 7.5 14.4 6.3 3.0 10.7 1.8 0.0 5.4 0.3 4.1 3.1 5.5 3.8 6.6 6.0 4.9 3.6 4.7 5.8 0.5 4.9 1.4 6.1 4.7 4.9 4.2 4.3 7.1 5.9 4.8 3.9 5.4 4.0 5.5 3.6 3.8 4.7 6.5 3.2 3.7 1.6 6.8 3.6 2.6 0.8 6.8 3.6 4.7 5.8 1.8 20.0 1.0 40.5 2.1 4.1 1.3 7.4 129.1 3.2 1.2 0.1 0.6 5.5 6.0 15.6 3.4 3.0 3.6 2.4 3.6 0.3 4.5 2.9 9.7 428.5 8.3 6.7 2.7 89.6 4.1 11.9 2.0 6.2 1.8 10.8 8.8 0.0 1.9 9.8 4.1 2.5 2.3 2.1 95.7 1.5 8.0 0.7 1858.7 1019.7 0.0 5.4 0.0 5.0 5.0 1.1 5.8 4.6 6.8 9.4 6.8 0.8 82.6 2.2 KIAA0319 NMIG ENSG00000137261 KIAA0319 Q5VV43 6 24544104-24646191 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 12.3;pituitary gland: 4.1" "Group enriched" "Detected in some" 8 "Astrocytes: 119.5;Early spermatids: 65.6;Excitatory neurons: 129.2;Inhibitory neurons: 72.7;Late spermatids: 96.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.6" "Lineage enhanced" "Detected in single" "granulocytes: 1.6" "Cell line enhanced" "Detected in some" "A-431: 2.0;A549: 2.0;GAMG: 2.1;HDLM-2: 2.4;HeLa: 1.9;SCLC-21H: 3.8;U-266/84: 3.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015607, HPA076313" Enhanced Supported Approved Vesicles "Secreted in brain" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA015607: AB_1852299, HPA076313: AB_2732308" "unprognostic (1.64e-1)" "unprognostic (2.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.31e-1)" "unprognostic (1.08e-1)" "unprognostic (1.77e-1)" "unprognostic (1.72e-2)" "unprognostic (4.65e-2)" "unprognostic (9.70e-2)" "unprognostic (2.21e-5)" "unprognostic (7.88e-4)" "unprognostic (9.53e-4)" "unprognostic (1.44e-6)" "unprognostic (1.20e-1)" "unprognostic (6.97e-2)" "unprognostic (3.13e-1)" "unprognostic (3.41e-2)" 0.0 0.4 10.0 0.2 10.3 0.0 0.1 4.3 10.4 0.1 0.6 0.4 0.0 0.0 0.0 0.0 1.6 0.2 0.0 9.2 5.8 0.0 0.0 0.6 0.0 7.2 7.4 0.0 1.4 0.1 4.1 0.0 7.6 0.4 0.4 1.2 0.2 0.0 0.0 0.7 0.2 0.1 2.7 0.2 0.8 1.1 12.3 0.0 0.0 0.0 0.1 0.0 0.0 4.8 2.0 2.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.6 0.9 0.0 2.1 0.8 0.3 0.0 0.0 2.4 1.0 0.0 1.9 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.5 0.0 0.0 0.2 0.1 0.1 0.1 0.0 0.3 0.0 0.1 3.8 0.2 0.0 1.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.1 0.4 0.3 3.2 0.1 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 10.0 10.3 4.3 10.4 9.2 5.8 7.2 7.4 7.6 2.7 12.3 4.8 0.1 3.2 0.5 119.5 0.6 0.0 0.0 0.5 0.0 3.6 0.1 0.1 1.4 0.0 1.5 0.0 0.0 0.0 0.0 1.4 0.0 0.4 65.6 2.6 0.1 0.0 10.2 0.0 129.2 0.0 0.0 0.3 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 72.7 0.8 0.0 0.0 0.0 96.8 0.6 0.2 0.0 5.6 0.6 0.3 0.0 5.0 3.1 0.3 0.1 0.7 0.0 0.2 0.0 0.1 10.9 0.9 0.0 0.1 0.0 1.2 1.5 0.0 0.0 0.7 0.1 0.1 0.3 0.3 KIAA0895L LOC653319 ENSG00000196123 "KIAA0895 like" Q68EN5 16 67175599-67184040 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 74.3;Early spermatids: 84.9;Horizontal cells: 107.7;Late spermatids: 198.4;Rod photoreceptor cells: 68.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065996 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" "HPA065996: AB_2685593" "unprognostic (8.71e-2)" "unprognostic (1.54e-1)" "unprognostic (8.11e-3)" "unprognostic (2.89e-2)" "unprognostic (2.15e-1)" "unprognostic (4.98e-2)" "unprognostic (1.79e-2)" "unprognostic (4.78e-2)" "unprognostic (4.89e-3)" "unprognostic (2.90e-1)" "prognostic favorable (3.16e-4)" "unprognostic (3.74e-2)" "unprognostic (2.67e-3)" "unprognostic (3.93e-2)" "unprognostic (2.82e-1)" "unprognostic (3.61e-1)" "unprognostic (1.00e-3)" 14.6 25.1 19.9 4.9 20.1 3.4 11.5 25.6 26.6 21.5 12.4 11.8 6.5 21.1 7.5 12.4 30.8 6.0 11.7 21.0 18.8 19.2 9.3 14.5 2.1 21.2 17.3 39.7 11.7 6.6 46.1 5.7 21.3 17.1 5.2 29.2 10.8 4.1 5.1 9.3 11.2 7.1 15.9 16.2 14.4 23.5 17.7 4.1 25.3 2.2 1.7 15.5 13.3 20.4 3.1 5.0 19.0 11.9 3.6 8.2 12.3 7.9 1.6 3.6 3.4 5.1 3.1 5.7 5.0 3.3 3.0 11.6 5.4 4.5 2.3 5.2 7.1 8.3 15.6 4.7 2.8 3.8 16.2 4.7 2.0 4.5 1.7 13.4 6.0 12.2 8.6 5.3 4.6 5.1 8.6 6.4 4.1 3.1 8.2 23.0 9.1 11.1 6.3 7.3 21.6 18.0 9.4 4.7 2.6 9.0 10.2 6.4 7.0 11.8 8.4 5.8 3.4 6.6 5.9 6.0 15.3 5.7 6.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 19.9 20.1 25.6 26.6 21.0 18.8 21.2 17.3 21.3 15.9 17.7 20.4 5.3 3.2 7.9 29.4 1.3 2.9 3.8 7.0 7.4 74.3 6.3 6.9 3.3 8.6 8.8 7.3 43.8 3.9 2.3 6.6 3.9 5.6 84.9 6.7 14.9 5.8 13.1 1.7 23.6 2.5 6.7 5.4 10.7 10.8 4.5 18.6 7.1 4.3 4.2 107.7 28.9 4.6 10.2 0.6 2.1 198.4 6.8 2.3 5.4 5.6 1.7 13.8 0.0 20.1 14.9 3.4 5.4 10.9 1.2 4.5 2.1 1.9 5.1 68.0 19.7 2.8 8.8 6.9 10.9 5.9 2.4 3.0 2.0 16.3 6.6 4.8 KIAA1210 ENSG00000250423 KIAA1210 Q9ULL0 X 119078635-119150579 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "epididymis: 39.4;seminal vesicle: 19.8;testis: 30.9" "Cell type enhanced" "Detected in some" "Early spermatids: 4.0;Endometrial stromal cells: 25.2;Granulosa cells: 11.1;Late spermatids: 11.5;Peritubular cells: 6.0" "Cancer enhanced" "Detected in single" "prostate cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "MCF7: 1.0" "Not detected" "Not detected" "HPA000551, HPA048322" Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 36: Stromal cells - Cell proliferation" "Golgi apparatus, Vesicles" "HPA000551: AB_1079165, HPA048322: AB_2680358" "unprognostic (2.48e-1)" "unprognostic (5.63e-2)" "unprognostic (1.77e-1)" "unprognostic (1.43e-1)" "unprognostic (3.90e-1)" "unprognostic (2.25e-2)" "unprognostic (1.16e-2)" "unprognostic (6.29e-2)" "unprognostic (2.53e-1)" "unprognostic (1.06e-1)" "unprognostic (2.92e-2)" "unprognostic (5.69e-2)" "unprognostic (1.05e-1)" "unprognostic (8.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.24e-1)" "unprognostic (6.26e-4)" 0.0 1.4 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 1.6 39.4 0.0 5.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 4.7 0.0 0.0 0.0 19.8 0.3 0.0 0.0 0.2 0.0 0.0 0.0 30.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.2 0.4 1.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 4.0 1.9 25.2 0.2 0.0 0.0 0.1 0.0 0.2 0.3 0.0 1.6 0.0 11.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 11.5 3.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.5 2.4 1.1 0.0 0.0 0.3 0.1 0.3 0.0 0.0 KIAA1328 ENSG00000150477 KIAA1328 Q86T90 18 36829106-37232172 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 75.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 230.8;Alveolar cells type 2: 228.3;Inhibitory neurons: 113.9;Oligodendrocyte precursor cells: 117.6;Oligodendrocytes: 178.0;Respiratory ciliated cells: 122.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040946 Approved Approved "Nuclear speckles,Vesicles,Lipid droplets" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 16: U-266 - Nucleosome" "Cluster 11: Alveolar cells - Smell perception" "Nuclear speckles" "Vesicles, Lipid droplets" "HPA040946: AB_10794998" "unprognostic (3.66e-2)" "unprognostic (5.37e-4)" "unprognostic (2.76e-2)" "unprognostic (1.55e-3)" "unprognostic (1.59e-1)" "unprognostic (1.18e-2)" "unprognostic (2.46e-2)" "unprognostic (1.51e-3)" "unprognostic (1.99e-1)" "unprognostic (5.05e-2)" "unprognostic (3.18e-3)" "unprognostic (4.85e-2)" "unprognostic (1.06e-4)" "unprognostic (1.77e-1)" "unprognostic (2.25e-2)" "unprognostic (3.36e-2)" "unprognostic (2.64e-3)" 6.9 7.1 24.6 7.7 33.8 22.0 5.7 54.3 62.5 5.0 10.1 6.2 9.0 9.5 9.0 6.6 6.1 7.2 6.6 27.2 13.9 7.2 7.0 7.3 7.5 5.5 1.5 13.7 5.3 5.1 2.8 8.3 12.5 7.6 5.5 37.9 9.4 3.9 11.0 13.6 9.4 5.5 0.6 8.3 9.0 16.8 12.6 4.0 7.0 4.1 4.6 4.6 3.6 75.8 26.2 7.4 11.2 13.5 3.8 5.8 10.5 10.7 4.0 5.1 3.4 12.9 16.4 18.1 32.8 4.1 8.6 11.7 4.2 4.7 6.4 15.3 5.0 22.9 24.6 9.3 3.6 16.0 11.9 5.4 5.8 5.6 5.0 5.5 4.4 10.9 18.1 40.7 5.0 23.0 10.6 10.6 25.0 9.6 11.4 14.0 11.9 12.8 4.2 22.2 11.7 13.5 12.8 15.9 6.7 20.4 23.3 8.3 13.8 22.4 29.5 13.3 11.2 32.2 43.8 14.4 11.0 11.3 15.4 23.8 6.7 9.9 8.2 5.0 9.8 7.4 7.2 7.0 3.2 11.4 9.3 7.5 13.2 7.4 8.0 5.5 9.4 4.0 24.6 33.8 54.3 62.5 27.2 13.9 5.5 1.5 12.5 0.6 12.6 75.8 10.9 230.8 228.3 85.5 13.3 5.7 7.9 7.0 6.8 36.1 6.5 7.1 6.0 7.2 106.8 5.5 20.9 8.8 6.5 1.7 5.9 7.6 51.9 6.8 10.5 18.2 3.0 5.5 83.8 5.8 7.8 23.9 5.1 6.9 107.9 13.5 9.7 3.0 6.6 16.8 113.9 3.2 2.0 4.4 4.6 13.0 9.3 18.3 7.2 94.6 5.0 10.1 19.6 117.6 178.0 6.3 3.7 7.9 8.0 3.6 4.4 4.4 122.7 30.9 0.0 14.3 11.0 45.3 19.6 6.6 7.0 3.8 20.6 11.5 4.5 5.0 KIAA1549L "C11orf41, C11orf69, G2, MGC34830" ENSG00000110427 "KIAA1549 like" Q6ZVL6 11 33376108-33674102 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "brain: 26.4;parathyroid gland: 33.5" "Group enriched" "Detected in some" 6 "Excitatory neurons: 366.9;Inhibitory neurons: 193.5" "Cancer enhanced" "Detected in many" "melanoma: 4.4" "Group enriched" "Detected in many" 141 "amygdala: 8.6;basal ganglia: 14.9;cerebral cortex: 26.4;hippocampal formation: 12.3;white matter: 7.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "TIME: 42.4;U-138 MG: 53.8;WM-115: 37.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010132, HPA051594" Approved Nucleoplasm,Vesicles NA NA 160000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Vesicles "HPA010132: AB_1078313, HPA051594: " "unprognostic (3.02e-1)" "unprognostic (1.18e-1)" "unprognostic (2.70e-2)" "unprognostic (1.34e-5)" "unprognostic (2.63e-1)" "unprognostic (7.92e-2)" "unprognostic (2.89e-2)" "unprognostic (5.27e-3)" "unprognostic (1.55e-2)" "unprognostic (2.59e-4)" "unprognostic (8.88e-2)" "unprognostic (1.44e-1)" "unprognostic (3.62e-3)" "unprognostic (1.08e-3)" "unprognostic (8.46e-2)" "unprognostic (4.04e-1)" "unprognostic (1.09e-1)" 0.2 0.4 8.6 0.2 14.9 0.0 0.7 0.0 26.4 0.1 0.0 0.3 0.0 0.1 0.0 0.7 0.0 0.3 0.1 12.3 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.2 0.3 33.5 0.7 1.1 0.0 0.0 0.1 0.9 0.3 0.0 0.1 1.8 0.0 0.1 0.0 0.0 0.1 0.8 0.0 0.1 0.0 0.1 0.7 0.3 0.2 7.9 0.1 1.9 6.1 0.2 1.0 6.5 0.0 24.7 14.4 3.8 2.1 0.0 0.6 18.7 0.3 21.9 19.2 1.4 0.9 7.3 5.7 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.0 2.6 0.1 6.4 11.0 13.4 16.9 0.5 0.2 20.5 15.1 0.0 0.2 0.0 1.4 0.0 9.1 0.0 1.6 0.0 0.0 9.6 2.2 2.2 0.3 0.0 6.2 0.2 0.0 0.0 42.4 53.8 11.8 1.3 19.6 0.0 0.0 0.0 14.7 0.0 37.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 14.9 0.0 26.4 12.3 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.2 0.0 0.0 18.3 0.1 2.0 0.6 0.6 0.0 5.6 2.2 2.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.9 0.8 1.1 0.2 0.1 0.7 0.0 0.0 366.9 0.0 0.2 1.0 0.0 0.6 0.0 0.2 5.0 0.2 0.3 3.3 193.5 0.0 0.0 0.0 0.9 1.2 0.0 0.1 17.8 18.7 0.0 0.1 0.0 40.2 7.2 1.2 0.0 0.4 0.0 1.2 0.0 0.1 0.1 0.4 0.0 0.1 1.8 0.0 1.8 0.6 0.3 0.0 0.0 0.1 0.0 0.7 KIAA1614 ENSG00000135835 KIAA1614 Q5VZ46 1 180912897-180951614 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 25.3" "Group enriched" "Detected in many" 13 "Bipolar cells: 95.3;Cone photoreceptor cells: 131.3;Rod photoreceptor cells: 176.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.3" "Cell line enhanced" "Detected in many" "RH-30: 17.8;SH-SY5Y: 44.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028227, HPA061684" Approved Approved "Nuclear membrane,Vesicles" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" "Nuclear membrane, Vesicles" "HPA028227: AB_10601765, HPA061684: AB_2684585" "unprognostic (3.23e-1)" "unprognostic (3.60e-2)" "unprognostic (3.17e-2)" "unprognostic (2.15e-2)" "unprognostic (1.05e-1)" "unprognostic (3.55e-2)" "unprognostic (8.76e-3)" "unprognostic (1.30e-1)" "unprognostic (1.38e-1)" "unprognostic (1.33e-1)" "unprognostic (3.15e-2)" "unprognostic (1.57e-1)" "unprognostic (8.61e-5)" "unprognostic (8.93e-2)" "unprognostic (8.88e-2)" "unprognostic (1.36e-2)" "unprognostic (1.35e-2)" 5.7 1.2 3.8 1.3 3.9 0.4 4.0 15.4 6.1 7.2 4.3 8.4 2.4 8.1 1.3 3.5 6.1 2.5 7.7 4.9 2.4 6.2 0.5 3.6 1.2 3.6 3.2 5.8 1.7 0.3 1.8 2.8 2.9 4.8 0.6 25.3 3.2 2.1 2.0 2.5 2.9 3.1 2.8 2.5 3.2 1.7 4.0 0.3 6.1 0.4 0.4 7.4 4.2 5.3 1.7 0.8 1.4 3.0 4.3 10.5 4.8 3.3 3.8 1.6 0.9 1.6 1.7 0.7 3.0 4.1 0.8 3.2 0.3 0.1 0.5 0.9 1.3 2.4 0.6 2.2 5.9 1.5 1.7 5.0 0.1 0.2 0.1 2.7 2.2 2.5 2.1 1.1 1.4 1.4 2.1 0.6 3.3 0.5 0.4 1.1 17.8 2.5 2.6 1.6 12.2 44.7 1.0 1.1 7.3 1.4 1.3 2.1 5.2 3.4 2.5 4.0 1.3 2.3 3.2 1.6 0.4 1.2 2.3 1.3 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.1 3.8 3.9 15.4 6.1 4.9 2.4 3.6 3.2 2.9 2.8 4.0 5.3 1.0 0.0 1.8 9.8 0.5 0.4 0.8 0.8 0.6 95.3 0.5 0.6 3.5 1.5 1.3 1.8 131.3 0.3 0.5 0.0 1.9 0.4 4.6 0.8 3.6 2.1 0.0 0.0 5.0 0.2 0.4 3.3 0.0 2.2 1.3 1.6 1.8 0.1 1.8 3.3 1.5 0.0 0.0 0.3 0.4 1.8 7.8 0.5 3.6 1.0 1.0 10.0 0.0 4.5 1.4 0.7 0.0 5.7 0.1 0.4 0.2 1.8 0.1 176.0 6.6 8.4 2.4 0.6 0.6 0.2 0.3 0.3 0.4 0.6 0.1 0.0 KIAA1755 RP5-1054A22.3 ENSG00000149633 KIAA1755 Q5JYT7 20 38210503-38260772 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 105.0" "Group enriched" "Detected in some" 4 "Astrocytes: 63.3;Microglial cells: 67.5;Oligodendrocytes: 135.6" "Cancer enhanced" "Detected in many" "melanoma: 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 75.6;ASC diff: 11.3;ASC TERT1: 16.9;WM-115: 19.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA051064 Approved Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoli "Golgi apparatus, Vesicles" "HPA051064: AB_2681331" "unprognostic (3.98e-3)" "unprognostic (2.20e-2)" "unprognostic (3.79e-1)" "unprognostic (3.01e-3)" "unprognostic (1.77e-1)" "unprognostic (7.01e-2)" "unprognostic (2.22e-1)" "unprognostic (1.11e-1)" "unprognostic (4.50e-2)" "unprognostic (2.70e-1)" "unprognostic (3.88e-2)" "unprognostic (1.69e-1)" "unprognostic (2.42e-8)" "unprognostic (1.41e-2)" "unprognostic (2.78e-2)" "unprognostic (1.25e-2)" "unprognostic (5.53e-3)" 5.6 2.1 18.4 6.0 87.7 0.5 3.4 39.2 42.2 13.1 0.0 9.0 2.4 14.6 6.4 5.1 8.7 16.2 11.4 29.0 64.1 4.1 1.2 2.5 5.0 59.2 62.3 13.6 0.9 0.1 2.2 0.1 54.7 6.6 4.2 0.5 5.8 7.3 0.6 1.4 4.2 14.7 18.3 2.7 3.6 2.6 75.3 8.3 2.0 1.7 4.7 5.2 4.8 105.0 3.0 0.3 75.6 0.1 11.3 16.9 0.0 7.6 4.3 0.0 0.0 0.3 2.2 0.0 0.3 2.4 2.5 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.3 0.0 2.2 1.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 2.0 0.1 0.0 0.0 0.4 0.0 1.1 0.4 1.4 0.0 0.0 0.0 0.2 0.0 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.4 87.7 39.2 42.2 29.0 64.1 59.2 62.3 54.7 18.3 75.3 105.0 0.1 0.0 0.0 63.3 0.0 0.3 0.0 0.0 0.0 0.0 0.8 1.8 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 1.5 0.1 2.5 0.2 0.0 0.0 0.8 0.0 0.0 4.4 0.0 0.6 0.0 0.0 0.4 1.1 0.1 0.0 0.5 0.0 0.0 0.0 0.5 1.9 3.7 0.2 1.8 67.5 0.0 0.0 0.0 19.6 135.6 0.6 0.0 7.5 0.0 0.0 0.0 4.1 0.0 0.0 0.0 1.1 1.2 0.3 0.3 0.2 0.3 0.0 0.0 0.4 0.0 0.0 KIAA2026 FLJ20375 ENSG00000183354 KIAA2026 Q5HYC2 9 5881596-6008482 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 26.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002109 Uncertain Approved Nucleoplasm,Vesicles,Cytosol No No "Cluster 37: B-cells - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 36: HEL - Hemostasis" "Cluster 52: Non-specific - Transcription" "Vesicles, Cytosol" Nucleoplasm "HPA002109: AB_1078071" "unprognostic (7.42e-2)" "unprognostic (2.79e-1)" "unprognostic (3.67e-2)" "unprognostic (1.52e-1)" "unprognostic (5.97e-3)" "unprognostic (1.61e-1)" "unprognostic (8.74e-2)" "unprognostic (6.86e-2)" "unprognostic (9.19e-2)" "unprognostic (8.41e-3)" "unprognostic (6.49e-2)" "unprognostic (1.52e-1)" "prognostic favorable (8.34e-4)" "unprognostic (2.41e-1)" "unprognostic (2.07e-1)" "unprognostic (1.76e-1)" "unprognostic (9.00e-2)" 6.8 5.1 13.5 5.6 17.2 6.4 6.2 24.1 11.7 7.8 25.1 6.4 4.8 7.9 5.8 6.1 6.4 5.7 5.7 9.9 12.1 6.1 4.9 5.9 6.7 11.6 13.3 10.2 5.2 8.6 6.2 6.9 11.9 6.2 5.0 10.4 6.1 5.4 9.5 8.2 5.6 6.3 10.3 8.1 6.5 11.5 12.6 8.3 8.4 9.5 5.9 6.2 7.1 17.0 7.1 3.5 7.2 4.6 5.4 8.5 3.2 4.6 6.8 4.4 4.0 2.3 4.0 8.8 1.7 5.8 5.5 3.5 4.2 3.9 6.5 19.2 3.0 26.5 8.4 3.7 4.2 9.4 11.6 5.3 5.0 3.9 6.4 8.3 6.9 5.7 2.8 16.2 5.5 2.2 5.1 17.2 4.0 4.1 2.8 5.3 4.6 4.5 4.8 4.9 9.3 5.3 4.3 4.0 3.7 4.9 4.1 12.6 7.8 8.4 4.7 4.2 5.3 11.1 9.5 8.8 4.3 4.3 2.3 5.0 2.3 7.0 4.2 1.9 4.8 5.9 4.1 3.8 0.9 3.8 4.5 4.8 6.0 4.8 4.5 2.9 2.6 0.8 13.5 17.2 24.1 11.7 9.9 12.1 11.6 13.3 11.9 10.3 12.6 17.0 47.8 44.8 34.0 99.9 40.3 44.6 29.9 21.4 37.5 89.0 33.5 25.5 53.7 42.9 22.1 38.6 79.2 17.1 51.9 31.0 7.9 18.2 33.0 28.3 40.9 39.7 38.5 18.7 97.8 13.4 10.6 33.2 31.1 46.7 20.2 43.5 29.3 18.7 16.9 45.4 119.1 34.7 16.2 25.5 28.8 17.2 70.5 31.9 23.2 113.4 55.1 47.7 95.8 116.1 170.1 18.4 29.1 76.3 35.4 34.4 30.1 11.9 18.2 81.5 46.0 45.8 40.1 127.7 121.2 38.3 52.4 30.0 45.1 38.7 28.5 42.0 KIF5C ENSG00000168280 "Kinesin family member 5C" O60282 2 148875227-149026759 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Transport "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 65.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 252.2;Early spermatids: 568.4;Excitatory neurons: 267.2;Inhibitory neurons: 249.1;Late spermatids: 702.5;Oligodendrocytes: 270.7" "Cancer enhanced" "Detected in many" "glioma: 11.7;prostate cancer: 19.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SCLC-21H: 117.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035210, HPA062272" Enhanced Approved Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA035210: AB_10671931, HPA062272: AB_2732678" "unprognostic (1.95e-1)" "unprognostic (2.39e-1)" "unprognostic (2.54e-1)" "unprognostic (4.70e-4)" "unprognostic (1.89e-1)" "unprognostic (3.79e-2)" "unprognostic (1.24e-1)" "unprognostic (3.90e-2)" "unprognostic (2.86e-1)" "unprognostic (1.41e-2)" "unprognostic (6.61e-3)" "unprognostic (1.56e-1)" "unprognostic (6.55e-6)" "unprognostic (8.34e-3)" "unprognostic (3.69e-1)" "unprognostic (3.63e-2)" "unprognostic (4.46e-2)" 0.5 5.1 41.3 0.6 17.6 0.0 0.5 13.9 65.2 1.4 0.0 1.1 0.3 0.5 3.7 0.1 0.9 0.1 0.6 28.9 13.7 0.2 0.0 0.2 0.3 15.4 9.0 1.6 2.3 0.3 5.5 0.0 24.6 10.4 0.6 7.8 0.2 2.8 0.3 0.3 0.8 0.4 16.3 0.2 0.6 12.1 49.8 0.1 1.3 0.9 0.2 0.6 1.4 32.0 0.0 0.0 17.8 3.6 0.0 0.0 0.0 0.0 0.0 0.8 0.6 0.2 0.0 0.7 0.0 0.2 5.4 0.0 14.1 0.0 1.3 13.7 3.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.2 0.7 0.0 0.7 0.0 0.1 0.0 0.8 0.0 0.0 22.4 0.0 9.2 0.0 0.1 0.1 0.0 3.6 117.1 27.1 0.2 0.5 0.2 2.8 0.0 0.0 0.0 0.0 3.3 0.0 3.7 3.0 0.4 0.0 8.8 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.3 17.6 13.9 65.2 28.9 13.7 15.4 9.0 24.6 16.3 49.8 32.0 1.8 0.0 0.0 33.6 2.4 1.3 6.1 0.1 2.2 252.2 8.0 3.7 14.9 4.3 0.0 18.4 108.4 0.0 0.8 1.1 0.0 0.3 568.4 0.9 1.6 6.1 129.7 0.0 267.2 0.0 0.1 4.9 2.0 0.2 0.0 1.1 0.7 0.0 0.2 99.3 249.1 2.7 4.1 0.3 1.9 702.5 8.1 0.8 5.4 10.3 0.8 8.5 2.1 125.2 270.7 0.9 3.4 12.8 1.7 35.8 0.1 0.1 0.0 15.1 6.6 1.6 9.1 15.8 10.7 0.2 0.4 0.0 11.9 0.3 4.9 2.3 KISS1 ENSG00000170498 "KiSS-1 metastasis suppressor" Q15726 1 204190341-204196491 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Cancer-related genes, Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "placenta: 233.1" "Cell type enriched" "Detected in many" 26 "Syncytiotrophoblasts: 1336.6" "Cancer enhanced" "Detected in many" "urothelial cancer: 9.2" "Region enriched" "Detected in some" 6 "hypothalamus: 10.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "BJ: 145.5;U-2 OS: 59.4" "Not detected" "Not detected" "CAB017775, HPA035542" Enhanced Approved Vesicles "Secreted in female reproductive system" NA NA 860000 "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "CAB017775: , HPA035542: AB_2674677" "unprognostic (9.64e-2)" "unprognostic (1.78e-2)" "unprognostic (1.86e-2)" "unprognostic (1.18e-2)" "unprognostic (3.89e-1)" "unprognostic (6.87e-2)" "unprognostic (1.87e-1)" "unprognostic (3.28e-2)" "unprognostic (1.28e-2)" "unprognostic (4.51e-2)" "unprognostic (1.63e-1)" "unprognostic (8.98e-12)" "unprognostic (2.25e-1)" "unprognostic (2.91e-2)" "unprognostic (1.76e-1)" "prognostic favorable (6.29e-6)" 0.0 0.0 0.4 0.0 0.8 0.0 0.1 0.6 0.6 0.3 0.8 0.2 0.9 0.2 0.0 0.1 0.1 0.0 0.1 0.4 10.7 2.4 4.3 1.3 0.0 1.8 0.3 0.0 1.0 0.0 3.1 233.1 0.4 0.6 0.0 0.0 0.1 0.0 0.0 0.1 1.3 0.2 0.2 2.0 3.2 5.2 1.0 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 2.4 145.5 1.8 2.5 0.7 0.0 0.7 0.0 1.4 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.9 0.2 0.0 0.2 0.1 0.0 0.0 0.9 0.2 0.1 0.0 0.7 0.0 0.8 0.2 0.3 0.0 0.1 59.4 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.6 0.6 0.4 10.7 1.8 0.3 0.4 0.2 1.0 0.3 0.3 0.0 0.0 0.3 0.0 0.0 4.0 7.5 0.0 1.0 1.2 0.6 0.0 1.5 2.2 0.0 0.0 9.3 0.0 1.5 0.0 11.3 40.2 0.2 0.0 1.4 0.0 0.0 0.1 4.9 6.9 1.9 4.1 0.5 0.0 0.4 0.7 2.8 15.1 0.0 0.0 0.6 0.0 0.0 0.0 5.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.5 0.0 0.1 50.1 17.0 1.4 0.4 0.0 0.0 0.0 7.1 0.6 1.1 0.0 0.0 1336.6 0.1 0.1 2.1 14.3 KISS1R "AXOR12, GPR54, HOT7T175" ENSG00000116014 "KISS1 receptor" Q969F8 19 917287-921005 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 8.5" "Cell type enriched" "Detected in some" 9 "Extravillous trophoblasts: 41.9" "Cancer enhanced" "Detected in many" "renal cancer: 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 15.7;RPMI-8226: 37.4;SCLC-21H: 7.4;SH-SY5Y: 20.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA007156, HPA071913" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 30: Non-specific - Translation" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 25: RPMI-8226 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" Vesicles "HPA007156: , HPA071913: AB_2686471" "unprognostic (1.54e-1)" "unprognostic (3.01e-2)" "unprognostic (9.42e-2)" "unprognostic (2.15e-1)" "unprognostic (8.46e-3)" "unprognostic (9.23e-2)" "unprognostic (1.65e-2)" "unprognostic (3.23e-1)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (7.17e-2)" "prognostic unfavorable (3.33e-6)" "unprognostic (1.87e-1)" "unprognostic (8.09e-3)" "unprognostic (1.05e-1)" "unprognostic (2.05e-2)" 0.0 0.0 2.9 0.1 1.8 0.0 0.0 0.9 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 3.8 0.3 0.1 0.1 0.1 4.0 2.2 0.0 1.3 0.3 1.1 0.1 3.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.0 0.4 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.7 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.3 4.1 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 15.7 0.0 0.0 0.3 0.1 0.0 0.6 1.2 0.4 1.0 0.0 37.4 0.0 0.0 7.4 20.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 2.9 1.8 0.9 3.4 1.3 3.8 4.0 2.2 3.9 1.0 8.5 0.8 0.1 0.0 0.0 0.0 1.0 0.1 0.1 0.5 0.0 1.1 1.2 1.4 0.5 0.0 0.2 0.0 0.0 0.4 0.2 0.1 0.0 0.7 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.2 41.9 0.1 0.0 0.4 0.0 0.1 0.0 0.1 0.7 0.0 0.7 0.0 0.0 0.0 1.5 0.0 0.0 0.3 1.8 0.0 0.0 0.2 1.0 0.0 0.0 0.1 0.0 0.0 4.2 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.4 0.0 0.3 0.3 0.3 1.6 0.9 0.2 0.1 0.2 KITLG "DFNA69, FPH2, Kitl, KL-1, MGF, SCF, SF, SLF" ENSG00000049130 "KIT ligand" P21583 12 88492793-88580851 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Cell adhesion" "Growth factor" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 83.6;Collecting duct cells: 69.9;Excitatory neurons: 46.5;Inhibitory neurons: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 299.8;SK-BR-3: 118.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070395 Approved Approved Vesicles "Intracellular and membrane" NA NA 260000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA070395: AB_2686264" "unprognostic (7.13e-2)" "unprognostic (1.90e-1)" "unprognostic (5.00e-2)" "unprognostic (2.05e-1)" "unprognostic (2.70e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (4.01e-4)" "unprognostic (2.22e-3)" "unprognostic (5.61e-3)" "unprognostic (7.89e-2)" "unprognostic (5.47e-3)" "unprognostic (5.03e-2)" "prognostic favorable (5.81e-7)" "unprognostic (7.15e-2)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (1.54e-2)" 13.2 3.9 2.3 8.2 3.5 0.3 10.6 0.2 3.1 12.9 1.2 18.7 9.6 15.1 2.8 14.3 4.0 18.5 7.0 2.9 0.3 16.0 2.3 31.6 3.3 0.0 2.5 6.0 3.7 3.7 0.2 15.0 0.0 15.1 22.6 2.3 8.8 14.8 3.1 7.1 11.6 18.8 0.3 3.5 17.4 6.3 5.2 5.1 5.9 14.4 10.4 12.3 1.3 6.2 14.3 7.1 7.1 0.9 29.0 61.5 0.0 77.6 60.1 13.5 6.4 299.8 11.0 0.0 2.2 73.3 14.9 49.5 11.5 20.1 14.2 0.1 9.5 0.0 9.5 2.6 4.4 1.9 0.0 53.5 20.6 41.6 26.8 6.3 17.9 0.0 0.0 0.3 6.8 2.5 0.2 0.0 4.8 17.7 17.9 0.0 12.6 0.0 25.0 6.5 2.3 4.8 18.5 118.9 2.2 6.5 57.2 4.3 10.0 60.7 7.4 69.0 6.8 0.0 0.0 0.0 8.4 0.2 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.5 0.2 3.1 2.9 0.3 0.0 2.5 0.0 0.3 5.2 6.2 42.5 19.2 38.3 9.4 0.5 13.5 11.2 7.5 83.6 2.7 12.2 8.1 4.4 1.5 16.5 69.9 0.0 0.1 0.0 12.0 1.9 4.4 0.4 3.1 6.8 43.1 9.5 0.0 46.5 18.2 0.1 34.5 43.3 3.4 0.0 2.1 5.0 0.4 1.2 21.9 61.4 8.5 18.3 3.2 5.7 0.9 14.0 1.9 12.4 18.7 0.0 0.3 0.0 3.0 0.6 8.7 3.0 3.8 1.4 11.2 2.3 1.4 9.8 1.2 13.1 2.2 27.2 0.2 0.5 18.5 5.3 0.0 1.0 4.4 14.7 3.2 KLF15 KKLF ENSG00000163884 "Kruppel like factor 15" Q9UIH9 3 126342635-126357408 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 92.5" "Cell type enhanced" "Detected in many" "Astrocytes: 22.9;Cardiomyocytes: 29.7;Distal tubular cells: 29.4;Hepatocytes: 66.9;Peritubular cells: 19.9;Proximal tubular cells: 22.1" "Cancer enhanced" "Detected in many" "liver cancer: 30.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 57.4;HHSteC: 34.8;RPMI-8226: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003286, HPA028866" Uncertain Supported "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "Nucleoplasm, Nuclear speckles" Vesicles "HPA003286: , HPA028866: AB_10600819" "unprognostic (3.77e-3)" "unprognostic (1.08e-1)" "unprognostic (1.99e-2)" "unprognostic (1.07e-2)" "unprognostic (2.72e-3)" "unprognostic (2.11e-1)" "unprognostic (4.63e-2)" "unprognostic (1.09e-2)" "unprognostic (2.91e-1)" "unprognostic (1.32e-1)" "unprognostic (3.58e-2)" "unprognostic (1.10e-1)" "prognostic favorable (3.27e-7)" "unprognostic (6.75e-2)" "unprognostic (7.65e-2)" "unprognostic (1.91e-2)" "unprognostic (5.58e-3)" 36.5 6.2 42.2 0.8 50.7 0.1 25.4 45.1 69.5 15.8 37.5 18.6 1.2 19.1 4.1 7.1 29.7 3.5 31.4 41.7 40.6 20.3 92.5 18.6 1.8 64.9 45.9 46.3 48.5 4.5 10.4 1.7 47.2 17.6 0.9 3.9 19.7 5.2 67.3 10.3 10.2 2.5 44.9 3.6 30.2 5.6 44.7 1.2 11.1 32.4 0.8 27.0 12.0 48.4 0.8 0.0 2.2 9.2 57.4 1.0 10.0 0.6 1.4 0.7 1.3 1.1 0.0 3.4 0.9 0.0 1.7 0.1 5.3 0.1 0.2 0.2 2.0 0.1 0.8 7.9 34.8 0.0 0.2 5.4 0.5 0.0 1.2 0.0 0.6 4.5 4.3 7.4 0.2 0.7 0.0 1.3 6.6 1.3 0.3 4.7 0.2 20.2 0.1 0.8 0.7 7.7 0.1 0.3 10.2 3.3 0.5 4.6 0.3 0.3 0.4 0.3 0.3 4.7 0.6 0.7 0.2 1.5 1.3 25.1 7.6 10.3 7.0 10.2 8.2 12.3 7.3 7.4 8.2 11.4 9.4 11.3 16.7 12.8 9.3 9.0 10.5 11.7 42.2 50.7 45.1 69.5 41.7 40.6 64.9 45.9 47.2 44.9 44.7 48.4 1.5 6.4 4.6 22.9 0.8 0.0 2.9 0.2 0.6 1.3 7.8 1.8 29.7 15.7 0.7 0.0 0.0 0.1 0.1 0.0 29.4 0.1 0.1 2.5 4.4 2.1 0.0 2.7 0.6 0.0 0.2 8.1 3.1 3.4 0.0 13.7 8.2 66.9 0.1 0.0 2.8 0.1 0.0 2.6 0.0 0.8 12.2 0.4 1.8 2.8 0.0 12.0 0.0 15.1 5.7 0.4 0.0 19.9 0.9 5.2 0.0 22.1 0.8 3.3 0.0 12.0 5.5 0.1 0.1 0.3 0.0 0.3 0.5 0.6 0.1 1.8 KLF5 "BTEB2, CKLF, IKLF" ENSG00000102554 "Kruppel like factor 5" Q13887 13 73054976-73077541 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 242.0;skin 1: 234.9" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 1105.5;Basal squamous epithelial cells: 757.5;Glandular and luminal cells: 678.2;Squamous epithelial cells: 1028.4;Suprabasal keratinocytes: 685.9;Urothelial cells: 1495.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 21 "basophil: 24.0" "Lineage enriched" "Detected in single" 140 "granulocytes: 24.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 111.8;HaCaT: 128.8;HBEC3-KT: 112.2;hTCEpi: 156.1;OE19: 246.3;RT4: 136.3;SiHa: 114.5" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 23.2" HPA040398 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Golgi apparatus, Vesicles" "HPA040398: AB_10673267" "unprognostic (7.90e-3)" "unprognostic (5.11e-2)" "unprognostic (2.03e-2)" "unprognostic (1.56e-1)" "unprognostic (4.69e-2)" "unprognostic (2.75e-1)" "unprognostic (1.18e-1)" "unprognostic (3.97e-2)" "unprognostic (5.82e-1)" "unprognostic (1.47e-2)" "prognostic unfavorable (2.55e-4)" "unprognostic (4.43e-2)" "unprognostic (1.42e-3)" "unprognostic (3.56e-3)" "unprognostic (3.98e-1)" "unprognostic (5.09e-2)" "unprognostic (1.54e-2)" 6.5 5.9 4.2 18.0 9.1 63.5 36.2 0.6 3.3 49.9 2.7 161.2 130.4 6.7 6.6 242.0 37.5 55.9 3.3 2.6 3.4 8.5 4.7 29.6 2.0 0.8 3.4 4.5 11.9 0.5 10.9 18.8 0.7 23.1 145.4 0.4 79.8 14.4 19.2 234.9 146.2 6.6 0.5 1.5 82.2 12.0 4.1 12.0 25.7 7.8 53.6 111.5 122.2 1.0 22.3 31.1 0.2 0.4 1.1 1.5 34.1 12.9 29.8 5.6 6.9 28.5 111.8 0.4 68.9 11.4 2.3 128.8 39.0 112.2 8.9 0.9 11.0 0.4 61.9 2.8 7.8 10.5 1.9 8.1 156.1 1.7 61.1 5.7 0.1 3.8 1.6 2.2 25.5 7.9 2.1 0.8 1.4 246.3 43.3 2.0 28.3 2.5 87.3 136.3 2.9 1.3 114.5 18.3 8.5 13.9 2.5 2.5 0.3 7.8 23.1 0.2 5.4 3.7 1.9 3.8 10.8 2.1 9.5 24.0 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.1 4.2 9.1 0.6 3.3 2.6 3.4 0.8 3.4 0.7 0.5 4.1 1.0 7.8 163.5 123.3 0.7 5.2 518.9 1105.5 185.6 757.5 0.4 79.9 57.0 6.0 91.5 218.5 36.8 2.1 77.8 4.6 420.7 21.5 31.8 448.3 302.1 44.1 12.5 203.2 0.4 1.6 46.1 98.5 33.4 425.1 678.2 3.8 0.9 2.2 4.7 6.1 10.1 11.6 387.4 46.8 0.9 34.6 241.4 6.5 12.4 58.7 1.9 4.3 0.0 1.0 1.0 0.6 88.6 374.9 1.5 15.7 632.1 260.0 3.5 159.3 0.2 0.0 38.4 32.4 8.8 26.3 1028.4 685.9 58.0 17.4 0.5 505.4 1495.5 KLF6 "BCD1, COPEB, CPBP, GBF, PAC1, ST12, Zf9" ENSG00000067082 "Kruppel like factor 6" Q99612 10 3775996-3785281 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 436.6" "Cell type enhanced" "Detected in all" "Squamous epithelial cells: 2075.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013529, HPA069585" Supported Supported Nucleoplasm,Nucleoli,Vesicles,Cytosol No No "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nucleoli, Vesicles, Cytosol" "CAB013529: AB_2533431, HPA069585: AB_2686157" "unprognostic (1.23e-1)" "unprognostic (1.53e-2)" "unprognostic (1.47e-3)" "unprognostic (4.53e-2)" "unprognostic (1.47e-1)" "unprognostic (7.55e-2)" "unprognostic (2.00e-1)" "unprognostic (1.08e-3)" "unprognostic (1.61e-1)" "unprognostic (2.83e-2)" "unprognostic (1.36e-2)" "unprognostic (2.35e-2)" "prognostic favorable (2.28e-4)" "unprognostic (8.07e-3)" "unprognostic (4.85e-2)" "unprognostic (6.87e-2)" "unprognostic (1.37e-2)" 211.3 46.9 19.0 122.1 18.0 436.6 129.7 19.2 22.4 95.4 21.9 92.1 55.4 98.1 17.7 165.5 77.2 181.9 49.7 18.0 19.2 64.1 141.8 117.0 65.4 29.4 20.1 47.3 118.3 31.8 12.0 98.2 25.2 32.8 99.6 18.4 73.8 33.7 84.9 197.1 106.0 208.2 22.7 64.3 73.2 14.6 23.0 56.8 193.9 41.3 45.0 136.3 92.7 25.0 55.0 14.7 27.2 9.0 155.1 154.3 17.1 91.7 46.5 95.9 64.8 38.0 71.4 15.6 20.8 100.0 74.5 32.7 17.0 84.9 79.5 76.6 10.2 2.2 17.5 35.8 66.4 10.3 51.5 51.4 158.2 68.6 129.3 34.2 99.3 10.1 17.5 117.9 123.6 4.0 19.4 15.9 10.2 29.2 26.0 12.6 28.2 55.5 94.1 53.4 12.0 11.5 22.5 64.0 142.8 73.5 32.0 8.6 130.9 128.7 17.8 76.9 43.0 22.6 78.1 28.6 34.7 13.7 40.8 318.8 85.2 234.1 129.8 74.2 115.9 81.1 147.4 131.5 67.6 70.9 44.9 69.0 391.6 72.5 104.6 152.8 120.6 148.7 19.0 18.0 19.2 22.4 18.0 19.2 29.4 20.1 25.2 22.7 23.0 25.0 511.0 1246.8 489.4 14.0 716.9 585.5 1298.4 625.8 1227.0 39.6 985.9 630.0 63.6 544.7 451.9 138.0 33.3 163.1 518.3 1507.0 21.5 808.6 58.0 1065.6 618.9 469.9 397.3 77.9 18.5 553.0 473.8 545.5 1120.3 1905.9 626.7 195.9 248.4 309.9 583.6 37.0 10.0 746.7 429.3 968.7 885.1 53.2 130.5 992.1 483.8 58.1 609.8 42.9 150.4 7.5 4.3 857.9 949.9 133.9 1172.5 600.2 1009.9 97.4 342.0 90.1 138.1 194.8 441.8 9.0 19.4 2075.6 628.2 195.9 920.5 67.1 542.0 572.5 KLHL12 C3IP1 ENSG00000117153 "Kelch like family member 12" Q53G59 1 202891116-202928636 "Predicted intracellular proteins" "ER-Golgi transport, Transport, Ubl conjugation pathway, Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 140.7;Late spermatids: 88.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071324 Supported "Vesicles,Centriolar satellite" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Vesicles, Centriolar satellite" "HPA071324: AB_2686389" "unprognostic (1.69e-2)" "unprognostic (2.84e-1)" "unprognostic (2.95e-2)" "unprognostic (1.97e-1)" "unprognostic (1.93e-1)" "unprognostic (4.86e-2)" "unprognostic (2.54e-3)" "unprognostic (3.35e-2)" "unprognostic (1.15e-2)" "unprognostic (9.11e-2)" "unprognostic (3.44e-1)" "unprognostic (1.58e-1)" "unprognostic (2.20e-3)" "unprognostic (6.22e-2)" "unprognostic (6.01e-2)" "unprognostic (3.32e-1)" "unprognostic (4.87e-2)" 13.3 15.8 26.4 14.6 26.8 18.8 17.3 24.7 27.8 13.8 23.9 19.4 14.5 14.9 22.7 15.8 18.4 12.3 20.4 27.5 29.8 21.8 16.2 15.0 19.0 24.6 26.5 17.7 16.3 21.2 15.2 15.6 27.6 19.3 23.4 24.6 13.7 13.6 14.3 13.5 14.8 17.3 24.6 17.1 16.0 44.8 28.5 20.4 19.8 18.3 22.4 14.2 13.1 26.4 20.4 24.5 30.2 34.3 46.2 34.2 35.6 24.1 28.0 29.7 27.0 23.3 33.0 57.8 18.5 27.7 29.8 25.8 40.5 33.8 32.3 29.9 17.6 20.1 19.5 23.6 33.4 42.3 31.7 33.0 43.0 25.7 56.1 23.5 26.8 56.9 51.5 36.7 41.3 28.0 35.6 20.4 43.4 25.8 18.3 36.5 52.8 37.0 26.1 25.7 22.5 25.8 29.9 27.6 33.2 54.7 49.2 29.4 22.0 29.0 20.2 7.1 21.7 26.4 22.5 48.0 28.6 29.9 28.3 7.5 10.1 15.6 6.9 12.3 10.2 7.1 6.9 8.3 10.5 6.7 7.3 7.9 10.1 8.3 13.2 6.1 11.1 9.2 26.4 26.8 24.7 27.8 27.5 29.8 24.6 26.5 27.6 24.6 28.5 26.4 7.0 6.4 11.5 12.7 13.3 5.4 9.4 8.9 6.2 11.2 8.5 5.7 16.6 12.8 9.2 16.5 12.5 11.9 9.3 17.6 23.5 12.1 140.7 8.6 7.8 7.8 10.8 15.8 14.9 8.9 12.1 9.3 5.6 7.4 3.8 15.0 8.6 7.8 17.2 5.0 19.3 13.2 6.1 15.9 5.6 88.1 8.4 12.9 5.4 14.0 16.8 11.3 10.3 11.1 18.6 11.4 10.1 8.2 9.3 8.7 11.6 15.9 8.2 10.2 6.6 6.9 7.6 26.0 44.9 9.2 6.7 11.1 11.5 9.5 12.5 7.2 KLHL2 MAV ENSG00000109466 "Kelch like family member 2" O95198 4 165207561-165323156 "Predicted intracellular proteins" "Ubl conjugation pathway" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 78.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 125.4;Oligodendrocytes: 144.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 7.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 7.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051637 Uncertain Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Vesicles "HPA051637: " "unprognostic (1.14e-1)" "unprognostic (8.11e-2)" "unprognostic (1.46e-1)" "unprognostic (8.31e-3)" "unprognostic (1.46e-1)" "unprognostic (1.56e-1)" "unprognostic (1.79e-1)" "unprognostic (3.11e-3)" "unprognostic (4.42e-2)" "unprognostic (2.06e-1)" "unprognostic (4.67e-1)" "unprognostic (4.88e-2)" "prognostic favorable (3.77e-4)" "unprognostic (4.21e-2)" "unprognostic (1.83e-1)" "unprognostic (2.30e-2)" "unprognostic (1.81e-1)" 11.8 11.8 35.3 12.1 50.9 21.4 13.0 26.7 55.8 5.9 14.3 7.2 5.3 7.7 13.5 19.7 9.9 10.7 5.5 78.4 34.7 15.4 27.1 14.2 11.2 33.2 35.7 4.1 7.8 9.5 16.3 7.7 30.8 8.2 6.7 8.8 20.0 10.0 4.7 6.4 6.5 10.7 33.3 14.6 8.3 6.1 35.5 6.3 12.3 6.8 9.5 15.2 8.8 45.2 16.1 14.7 9.8 10.1 14.1 12.9 10.2 21.3 16.7 10.7 11.7 8.9 11.5 16.3 5.1 10.9 19.2 10.5 16.1 10.4 13.9 27.2 6.0 14.1 12.8 12.9 12.9 14.2 19.3 10.7 30.5 9.8 37.1 18.5 25.9 6.1 6.4 33.0 16.1 6.0 0.4 4.0 6.0 8.9 6.5 5.6 7.0 5.1 18.1 14.9 49.1 8.1 13.5 4.5 13.0 18.1 3.3 15.1 37.0 8.4 17.6 9.6 14.0 21.5 16.3 13.2 10.1 9.7 16.9 1.8 0.9 1.3 0.5 1.0 0.3 0.3 0.3 0.3 0.8 0.8 0.9 1.0 7.2 0.3 1.2 0.4 0.5 0.4 35.3 50.9 26.7 55.8 78.4 34.7 33.2 35.7 30.8 33.3 35.5 45.2 19.0 6.4 17.9 33.3 10.7 6.0 13.1 8.0 4.6 8.9 13.2 10.9 4.7 8.6 9.7 22.0 14.6 4.3 8.3 7.5 27.4 8.7 1.9 8.3 6.6 14.6 15.5 2.1 125.4 12.9 9.4 5.2 8.2 13.5 9.5 4.0 25.7 35.6 8.3 32.0 33.0 6.2 8.2 42.5 13.9 1.7 4.1 22.7 5.4 39.4 13.5 5.8 1.0 43.2 144.5 9.6 7.4 4.5 6.3 11.9 5.4 19.0 10.9 7.3 0.0 11.9 7.2 3.3 7.4 7.7 7.5 3.7 9.2 3.9 3.9 20.1 KLHL22 "FLJ14360, KELCHL" ENSG00000099910 "Kelch like family member 22" Q53GT1 22 20441519-20495844 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 41.1;Excitatory neurons: 42.9;Inhibitory neurons: 51.1;Oligodendrocyte precursor cells: 41.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040766 Supported "Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 2: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA040766: AB_2732488" "unprognostic (4.15e-1)" "unprognostic (9.34e-3)" "unprognostic (5.37e-2)" "prognostic favorable (4.88e-6)" "unprognostic (1.17e-1)" "unprognostic (2.30e-3)" "unprognostic (1.00e-2)" "unprognostic (1.19e-3)" "unprognostic (2.20e-1)" "unprognostic (8.99e-2)" "prognostic favorable (3.85e-6)" "unprognostic (3.94e-2)" "prognostic favorable (1.34e-8)" "unprognostic (3.94e-2)" "unprognostic (3.10e-1)" "unprognostic (4.64e-2)" "unprognostic (1.08e-2)" 13.7 14.2 24.1 10.2 23.0 11.3 11.9 25.9 25.1 20.5 18.2 16.6 7.7 20.4 17.2 8.0 17.9 13.6 14.2 22.9 21.4 15.6 10.8 11.8 17.6 18.0 18.1 22.3 16.5 22.9 19.6 11.6 18.7 18.7 10.6 15.3 14.0 18.0 22.1 11.7 10.4 21.7 14.8 15.6 12.2 10.2 23.1 8.0 20.8 18.0 20.7 13.4 10.9 21.2 17.1 16.5 37.5 29.9 30.6 35.5 9.0 21.4 37.6 21.0 23.6 8.2 6.4 11.9 7.0 37.3 16.9 21.3 25.6 9.2 18.1 25.9 15.1 12.6 17.4 8.3 30.6 2.6 11.7 26.9 14.2 19.3 12.4 26.8 31.3 9.1 32.7 11.4 20.7 25.9 2.5 15.6 6.3 14.1 11.4 23.5 13.8 0.5 12.3 19.9 19.9 20.3 23.0 16.9 15.8 12.3 15.7 9.3 14.2 25.1 12.2 17.5 8.9 6.4 7.4 7.9 13.5 11.1 16.6 8.9 4.6 19.3 8.1 6.3 6.4 8.3 10.2 7.5 15.5 6.2 7.7 8.3 10.6 16.6 8.3 5.6 19.2 6.5 24.1 23.0 25.9 25.1 22.9 21.4 18.0 18.1 18.7 14.8 23.1 21.2 4.6 0.0 3.7 41.1 8.2 1.7 2.8 8.4 4.0 11.7 4.3 5.2 4.8 10.0 5.3 9.2 4.2 17.9 5.2 2.9 3.9 8.4 0.8 3.2 7.1 4.8 3.0 1.3 42.9 2.6 6.6 9.2 5.1 3.9 5.1 14.2 4.2 6.3 7.9 13.5 51.1 5.2 12.2 5.7 4.9 1.8 12.2 4.8 1.8 16.9 4.2 13.9 7.2 41.2 26.8 5.6 3.5 19.9 5.4 3.9 3.0 10.9 4.3 6.7 6.6 4.7 5.3 17.3 15.4 2.8 1.4 13.4 7.8 17.7 3.8 1.8 KLK8 "HNP, neuropsin, ovasin, PRSS19, TADG14" ENSG00000129455 "Kallikrein related peptidase 8" O60259 19 50996007-51002711 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 118.0;skin 1: 87.1;vagina: 47.2" "Group enriched" "Detected in some" 5 "Basal keratinocytes: 66.0;Suprabasal keratinocytes: 180.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 29.9;ovarian cancer: 30.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "A-431: 88.3;CAPAN-2: 112.2;HaCaT: 83.5" "Region enriched" "Detected in all" 5 "hippocampal formation: 36.1" "Region enhanced" "Detected in single" "basal ganglia: 1.2" "CAB019393, HPA035761" Enhanced Approved Vesicles "Secreted in other tissues" NA NA 3200000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" Vesicles "CAB019393: , HPA035761: AB_2674769" "unprognostic (4.27e-3)" "unprognostic (2.59e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (2.31e-4)" "unprognostic (5.46e-2)" "prognostic unfavorable (5.72e-4)" "unprognostic (2.95e-1)" "unprognostic (9.02e-2)" "prognostic unfavorable (1.10e-4)" "unprognostic (4.29e-2)" "unprognostic (4.66e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (6.17e-4)" 5.7 0.0 0.1 0.0 0.0 0.0 8.4 0.8 0.7 24.7 0.2 0.0 0.0 0.9 0.4 118.0 13.2 0.1 0.2 0.0 0.0 0.4 0.1 0.1 0.0 0.7 0.2 0.1 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.0 17.1 0.1 0.7 87.1 0.0 0.1 0.0 0.2 0.1 1.2 0.2 1.1 0.5 0.0 9.6 0.0 47.2 0.5 88.3 0.0 0.0 0.6 0.0 0.0 12.3 0.0 0.0 0.0 0.0 1.7 112.2 0.0 2.2 0.0 0.1 83.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.7 10.3 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.7 0.0 0.0 0.7 0.2 0.4 0.0 0.2 0.5 0.1 0.0 0.0 0.0 0.3 66.0 0.0 0.4 14.8 0.0 13.0 15.6 0.1 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.7 11.0 0.3 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.7 5.0 1.8 0.1 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.3 2.8 6.2 21.1 180.1 0.0 0.2 0.0 0.2 0.1 KLRC3 NKG2-E ENSG00000205810 "Killer cell lectin like receptor C3" Q07444 12 10412315-10420595 "Predicted membrane proteins" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.9;brain: 2.1;lymphoid tissue: 4.0" "Group enriched" "Detected in some" 4 "dendritic cells: 19.2;Oligodendrocyte precursor cells: 36.2;T-cells: 15.9" "Cancer enriched" "Detected in single" 9 "glioma: 0.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "NK-cell: 63.1" "Lineage enriched" "Detected in many" 6 "NK-cells: 63.1" "Cell line enhanced" "Detected in some" "ASC TERT1: 1.4;GAMG: 2.8;HEL: 1.3;HeLa: 7.0;HSkMC: 1.2;SuSa: 1.3;U-698: 1.9" "HPA039910, HPA062570" Approved Uncertain Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA039910: , HPA062570: AB_2684795" "unprognostic (8.92e-4)" "unprognostic (4.47e-2)" "unprognostic (2.03e-2)" "unprognostic (1.32e-1)" "unprognostic (5.07e-3)" "unprognostic (2.48e-1)" "unprognostic (3.22e-1)" "unprognostic (9.12e-2)" "unprognostic (3.52e-3)" "unprognostic (3.09e-1)" "unprognostic (1.08e-1)" "unprognostic (3.15e-1)" 0.2 0.1 1.3 0.3 1.4 1.9 0.1 0.7 2.1 0.1 0.2 0.5 0.8 0.5 0.1 0.2 0.2 0.6 0.0 1.3 1.7 0.1 0.5 0.6 1.7 1.7 1.1 0.1 0.1 0.0 0.0 0.1 1.2 0.1 0.4 0.0 0.1 0.0 0.0 0.0 1.3 0.1 1.3 4.0 0.6 0.2 1.3 0.4 0.1 0.0 0.8 0.1 0.1 2.1 0.0 0.0 0.1 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.6 0.0 0.0 0.0 1.3 7.0 0.1 0.0 0.1 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.5 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.1 0.0 0.0 7.0 0.0 0.0 0.1 8.7 0.6 63.1 0.0 0.0 0.0 3.6 1.3 1.4 0.7 2.1 1.3 1.7 1.7 1.1 1.2 1.3 1.3 2.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.7 0.1 0.0 0.0 0.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 1.9 0.0 0.0 1.0 36.2 2.3 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 0.0 0.0 0.1 KLRG1 "2F1, CLEC15A, MAFA, MAFA-L" ENSG00000139187 "Killer cell lectin like receptor G1" Q96E93 12 8950044-9010760 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.4" "Group enriched" "Detected in many" 4 "dendritic cells: 93.7;granulocytes: 118.9;NK-cells: 164.8;T-cells: 109.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 390.9;MAIT T-cell: 461.3" "Lineage enriched" "Detected in all" 22 "T-cells: 461.3" "Cell line enhanced" "Detected in many" "HEL: 25.1;NTERA-2: 22.1;U-937: 17.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051403, HPA076494" Approved Enhanced Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA051403: , HPA076494: AB_2686800" "unprognostic (1.54e-2)" "unprognostic (8.42e-4)" "unprognostic (1.06e-1)" "unprognostic (1.28e-1)" "unprognostic (2.94e-1)" "unprognostic (1.53e-4)" "unprognostic (3.05e-1)" "unprognostic (2.27e-3)" "unprognostic (2.23e-2)" "unprognostic (1.01e-2)" "unprognostic (3.45e-3)" "unprognostic (6.88e-2)" "unprognostic (1.71e-2)" "unprognostic (2.05e-2)" "unprognostic (4.17e-2)" "unprognostic (4.96e-2)" "unprognostic (7.86e-2)" 4.1 1.7 2.4 3.8 2.6 3.0 2.5 4.3 2.9 1.3 1.4 1.5 1.0 1.2 2.1 1.0 1.0 3.3 2.0 2.1 3.2 1.4 3.0 2.2 10.4 2.5 3.4 1.0 0.5 0.4 1.1 0.6 2.3 1.1 1.9 1.3 1.6 0.7 1.7 1.0 2.2 1.6 1.7 8.8 1.6 1.1 2.6 2.5 1.0 1.8 5.0 2.4 0.8 3.8 0.2 3.1 1.6 2.3 3.0 0.7 1.4 0.5 0.3 0.4 1.1 1.1 1.1 4.9 0.1 0.4 2.1 0.2 3.3 0.5 0.4 3.6 1.9 25.1 0.4 1.6 0.8 1.1 1.6 1.4 0.4 0.5 0.0 0.4 7.6 2.5 1.4 0.4 0.2 0.7 1.0 2.0 22.1 1.0 1.7 1.2 1.0 0.0 0.5 0.4 0.4 4.4 1.1 0.5 1.6 4.3 0.3 1.7 0.8 0.7 1.0 0.6 1.4 1.4 4.1 2.6 1.8 17.3 0.2 17.5 2.6 1.5 390.9 2.9 461.3 4.2 85.1 237.7 8.2 5.0 23.5 147.7 5.7 20.9 5.4 3.9 8.7 99.7 2.4 2.6 4.3 2.9 2.1 3.2 2.5 3.4 2.3 1.7 2.6 3.8 12.7 0.0 4.3 2.9 4.7 0.4 0.4 0.0 4.0 5.0 1.0 0.9 2.8 1.5 0.1 0.0 8.4 1.0 93.7 0.1 1.9 0.7 1.6 0.8 0.6 2.9 1.2 24.6 3.8 0.2 0.5 1.3 0.5 0.5 118.9 0.9 25.7 2.0 3.4 5.0 3.6 0.1 0.0 9.1 1.4 3.1 0.6 3.7 1.8 2.8 5.4 1.8 164.8 9.5 6.2 0.3 0.1 0.0 16.9 0.2 0.3 3.1 0.1 3.9 0.0 2.1 1.0 7.8 7.3 1.3 0.0 0.3 109.3 0.7 0.6 0.1 KNDC1 "bB439H18.3, C10orf23, FLJ25027, KIAA1768, RASGEF2, v-KIND, Very-KIND" ENSG00000171798 "Kinase non-catalytic C-lobe domain containing 1" Q76NI1 10 133160219-133226412 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.0;pituitary gland: 27.5" "Cell type enhanced" "Detected in many" "Astrocytes: 93.4;Excitatory neurons: 41.9;Inhibitory neurons: 36.3;Respiratory ciliated cells: 25.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.6;EFO-21: 1.2;MCF7: 1.1;NTERA-2: 1.4;RPMI-8226: 2.1;SuSa: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039624, HPA056143" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 38: EFO-21 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane, Cytosol" Vesicles "HPA039624: AB_10671045, HPA056143: " "unprognostic (2.32e-1)" "unprognostic (1.11e-1)" "unprognostic (6.35e-4)" "unprognostic (1.59e-3)" "unprognostic (1.96e-2)" "unprognostic (2.76e-1)" "unprognostic (5.61e-2)" "unprognostic (2.75e-2)" "unprognostic (6.77e-2)" "unprognostic (1.15e-1)" "unprognostic (6.80e-3)" "unprognostic (2.46e-3)" "unprognostic (1.18e-1)" "unprognostic (1.25e-1)" "unprognostic (2.53e-1)" "unprognostic (1.94e-1)" "unprognostic (9.41e-2)" 1.5 13.7 31.1 0.1 17.9 0.0 0.2 8.4 44.0 2.3 0.0 0.3 0.0 2.8 0.7 0.2 9.0 0.2 0.3 19.8 9.1 0.8 6.5 2.8 0.0 17.3 13.3 8.5 0.5 0.4 27.5 0.4 10.3 1.1 0.0 0.9 0.6 0.9 0.0 0.2 0.2 0.4 3.0 0.5 0.3 1.8 22.7 0.0 2.5 0.0 0.0 0.2 0.9 13.1 0.2 0.3 0.2 1.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.6 0.2 0.0 1.2 0.1 0.5 0.2 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 1.4 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 31.1 17.9 8.4 44.0 19.8 9.1 17.3 13.3 10.3 3.0 22.7 13.1 0.0 0.0 9.0 93.4 0.2 0.0 0.1 0.4 0.0 1.6 0.2 0.0 2.4 1.5 4.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 14.2 1.5 0.2 3.0 0.0 41.9 0.0 0.1 1.4 0.0 0.3 0.0 1.5 0.4 4.6 0.2 1.7 36.3 0.0 0.0 1.0 0.4 1.0 3.7 1.2 0.0 5.6 0.3 4.5 0.0 6.6 2.1 0.0 0.0 1.2 0.0 0.1 0.0 0.0 25.9 1.0 0.0 0.1 0.5 0.0 1.7 0.0 0.3 0.1 0.4 1.2 0.0 0.0 KPTN 2E4 ENSG00000118162 "Kaptin, actin binding protein" Q9Y664 19 47475150-47484265 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 23.9" "Lineage enriched" "Detected in all" 4 "dendritic cells: 23.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041710, HPA041796" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane" "Nucleoplasm, Vesicles" "HPA041710: AB_10961904, HPA041796: AB_10962832" "unprognostic (4.80e-3)" "unprognostic (2.22e-1)" "unprognostic (7.24e-2)" "unprognostic (1.53e-1)" "unprognostic (5.54e-2)" "unprognostic (3.47e-2)" "prognostic unfavorable (7.91e-6)" "unprognostic (9.30e-2)" "unprognostic (2.24e-1)" "unprognostic (2.21e-2)" "unprognostic (5.51e-2)" "unprognostic (2.59e-2)" "prognostic unfavorable (7.82e-4)" "unprognostic (1.40e-1)" "unprognostic (8.72e-2)" "unprognostic (2.04e-1)" "unprognostic (2.34e-1)" 5.2 6.6 5.1 3.0 5.5 5.6 4.7 5.9 8.4 7.2 3.6 6.2 3.4 5.3 1.4 7.7 4.4 2.4 5.8 5.6 5.1 6.3 8.6 4.5 3.4 5.6 5.1 3.2 5.5 4.0 10.0 2.8 5.0 8.0 2.2 1.6 10.1 2.0 6.9 4.8 4.5 2.6 4.6 6.1 4.7 5.4 5.1 8.2 4.8 6.7 2.1 5.1 5.8 5.4 9.7 16.8 12.9 8.6 12.9 10.0 9.3 5.4 9.9 28.4 17.5 12.6 11.3 12.3 4.1 9.5 10.1 11.1 11.0 19.1 7.9 11.4 17.2 5.2 12.2 11.4 11.5 10.1 13.8 11.5 12.3 9.5 8.7 7.2 11.0 15.2 10.1 10.9 8.3 7.8 17.7 44.8 11.6 10.5 10.3 12.6 6.3 4.8 8.8 15.0 27.8 21.1 9.1 10.3 6.8 6.4 8.5 14.5 6.6 6.9 7.6 3.7 12.2 2.8 4.8 5.3 6.1 6.4 10.4 0.0 3.9 1.7 1.4 3.4 0.4 1.5 1.0 1.2 4.6 1.6 1.3 1.1 3.2 1.2 5.3 23.9 1.7 2.2 5.1 5.5 5.9 8.4 5.6 5.1 5.6 5.1 5.0 4.6 5.1 5.4 2.6 3.2 2.7 4.6 4.8 2.8 8.5 13.8 2.8 5.8 5.8 3.9 3.7 4.3 8.9 5.5 6.2 14.5 12.1 3.4 9.8 9.6 0.8 3.1 3.3 3.0 3.0 0.8 4.7 4.2 13.3 5.0 5.1 3.4 2.5 4.9 3.3 6.2 8.5 10.1 3.5 2.5 8.2 5.6 2.8 2.5 1.2 5.8 1.8 1.9 2.5 6.9 5.2 3.0 4.3 5.0 1.8 0.7 6.5 4.4 4.3 8.3 2.9 4.0 0.0 3.5 3.5 4.9 18.9 4.5 3.1 15.3 1.7 8.2 4.0 5.8 KRIT1 "CAM, CCM1" ENSG00000001631 "KRIT1 ankyrin repeat containing" O00522 7 92198969-92246166 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 177.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049606 Supported Uncertain Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "HPA049606: AB_2680832" "unprognostic (8.12e-2)" "unprognostic (1.11e-2)" "unprognostic (1.83e-2)" "unprognostic (3.75e-2)" "unprognostic (1.94e-1)" "unprognostic (8.93e-2)" "unprognostic (4.10e-3)" "unprognostic (1.06e-2)" "unprognostic (2.30e-3)" "unprognostic (2.18e-1)" "unprognostic (7.24e-2)" "unprognostic (1.04e-1)" "unprognostic (1.19e-1)" "unprognostic (2.82e-1)" "unprognostic (2.61e-1)" "unprognostic (6.18e-2)" "unprognostic (1.04e-1)" 11.4 13.6 6.5 16.2 8.9 8.5 11.8 15.8 11.3 13.1 11.7 12.1 14.5 17.1 14.1 13.3 14.0 15.7 18.9 7.4 9.5 14.1 12.1 10.7 14.7 6.7 6.9 20.3 15.9 23.8 11.4 13.6 7.9 12.1 12.6 16.3 14.1 11.2 16.3 14.0 12.2 14.1 5.7 14.7 13.7 18.8 7.8 19.4 22.4 17.5 15.8 13.6 10.8 14.2 27.6 22.0 26.8 27.4 21.2 15.9 19.6 25.5 18.3 12.0 12.3 18.8 31.1 25.9 24.6 14.8 25.9 24.1 21.9 12.7 18.5 23.0 31.4 25.2 26.6 13.2 15.2 34.9 34.5 22.3 21.8 15.0 16.9 20.7 16.2 21.8 51.4 40.5 18.9 30.7 40.6 26.0 26.6 22.4 16.3 28.4 35.5 34.1 10.8 30.9 27.4 33.5 27.7 38.3 22.9 28.2 22.0 20.6 25.1 37.3 28.2 46.9 18.3 25.6 31.1 50.4 19.5 29.6 34.4 13.4 5.5 5.4 6.5 4.0 6.6 10.8 7.5 9.5 5.6 8.5 9.5 8.3 2.2 12.0 2.9 7.6 7.7 3.3 6.5 8.9 15.8 11.3 7.4 9.5 6.7 6.9 7.9 5.7 7.8 14.2 40.6 16.0 34.3 47.0 38.9 19.9 25.7 27.3 40.5 43.7 35.5 34.3 27.6 20.0 26.8 42.3 33.3 37.3 39.2 22.0 46.9 24.0 29.7 30.0 44.1 36.2 20.4 29.2 76.9 24.2 30.0 39.7 35.7 27.9 36.7 49.4 44.6 29.7 19.3 28.6 92.6 23.1 20.3 22.1 16.2 19.5 51.3 23.4 7.2 35.6 29.9 39.9 41.2 46.8 115.4 22.1 33.1 54.2 38.0 22.4 32.2 36.3 36.9 53.1 39.5 43.8 36.8 177.1 90.1 43.1 25.1 28.0 33.0 41.8 23.7 20.5 KRT222 "KA21, KRT222P, MGC45562" ENSG00000213424 "Keratin 222" Q8N1A0 17 40654665-40665181 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.7;retina: 8.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 53.9;Excitatory neurons: 25.9;Horizontal cells: 28.6;Inhibitory neurons: 24.4;Muller glia cells: 46.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "RPTEC TERT1: 9.7" "HPA054586, HPA068724, HPA069774" Enhanced Approved "Vesicles,Lipid droplets" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Lipid droplets" "HPA054586: AB_2682532, HPA068724: , HPA069774: AB_2686195" "unprognostic (2.72e-2)" "unprognostic (4.08e-2)" "unprognostic (1.92e-1)" "unprognostic (2.43e-1)" "unprognostic (1.26e-2)" "unprognostic (3.50e-1)" "unprognostic (1.27e-1)" "unprognostic (6.12e-2)" "unprognostic (5.59e-1)" "unprognostic (2.04e-1)" "unprognostic (1.04e-2)" "unprognostic (1.82e-1)" "unprognostic (1.49e-2)" "unprognostic (3.18e-1)" "unprognostic (1.00e-1)" "unprognostic (1.79e-1)" "unprognostic (7.41e-2)" 1.2 2.7 4.8 0.1 5.5 0.0 0.3 6.1 9.7 0.4 0.0 0.5 0.4 0.5 5.0 0.3 0.3 3.3 0.3 5.0 4.0 0.5 2.8 0.2 0.1 3.8 3.5 0.1 0.5 0.7 1.8 0.0 3.9 1.1 0.5 8.0 0.2 1.4 0.0 0.1 0.9 0.5 1.8 1.8 0.3 0.3 4.1 0.4 0.7 0.1 0.1 0.3 0.4 5.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 5.5 6.1 9.7 5.0 4.0 3.8 3.5 3.9 1.8 4.1 5.1 1.5 0.0 0.5 1.3 0.0 0.1 0.8 0.0 1.8 53.9 1.0 0.6 0.5 10.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 0.4 0.0 0.1 4.3 0.0 0.0 25.9 0.2 0.2 2.5 0.0 0.0 2.5 0.0 2.2 3.5 0.0 28.6 24.4 0.2 0.0 0.3 0.3 0.6 6.5 0.0 0.0 2.8 0.0 46.7 0.0 1.5 2.1 0.1 0.0 0.7 0.0 0.1 1.2 2.7 0.0 8.9 0.0 0.0 0.2 0.2 1.2 0.9 0.0 0.1 0.1 0.0 0.1 0.1 KRT25 KRT25A ENSG00000204897 "Keratin 25" Q7Z3Z0 17 40748021-40755331 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 42 "skin 1: 112.3" "Cell type enhanced" "Detected in some" "Early spermatids: 7.8;Late spermatids: 9.2;Spermatogonia: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "RPTEC TERT1: 1.3" "Region enriched" "Detected in some" 7 "cerebellum: 8.6" "Group enriched" "Detected in some" 5 "cerebral cortex: 7.3;hippocampal formation: 4.8" "HPA053977, HPA058943" Enhanced Approved Vesicles NA NA "Cluster 61: Skin - Cornification" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA053977: AB_2682329, HPA058943: AB_2683859" "unprognostic (8.19e-2)" "unprognostic (5.89e-8)" "unprognostic (1.79e-1)" 2.6 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 112.3 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KRT34 "Ha-4, KRTHA4" ENSG00000131737 "Keratin 34" O76011 17 41377650-41382403 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "skin 1: 66.6" "Group enriched" "Detected in some" 8 "Early spermatids: 5.4;Late spermatids: 15.6" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "BJ: 201.8" "Not detected" "Not detected" "HPA055194, HPA072208" Enhanced Approved Nucleoplasm,Vesicles NA NA 170000000 "Cluster 61: Skin - Cornification" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" "HPA055194: AB_2682733, HPA072208: AB_2686494" "unprognostic (2.52e-1)" "unprognostic (2.14e-1)" "unprognostic (9.03e-2)" "unprognostic (2.94e-1)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (2.86e-3)" "unprognostic (5.12e-7)" "unprognostic (3.84e-2)" 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 66.6 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 1.1 1.8 0.0 1.6 0.0 0.0 0.0 0.1 1.9 0.0 201.8 8.8 23.5 46.4 0.0 0.1 0.0 0.0 25.1 0.1 0.0 0.0 0.0 42.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 8.2 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.4 6.1 26.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.4 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.3 0.1 0.0 0.3 0.0 0.0 KSR1 "KSR, RSU2" ENSG00000141068 "Kinase suppressor of ras 1" Q8IVT5 17 27456470-27626438 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 101.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 73.0;Glandular and luminal cells: 50.3;Inhibitory neurons: 50.2;Oligodendrocyte precursor cells: 53.3;Oligodendrocytes: 49.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 393.5;HEL: 140.5;HMC-1: 93.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009623, HPA011215, HPA011878" Uncertain Supported Vesicles,Cytosol NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" Cytosol Vesicles "CAB009623: AB_2265455, HPA011215: AB_1852649, HPA011878: " "unprognostic (2.03e-2)" "unprognostic (2.74e-1)" "unprognostic (2.60e-1)" "unprognostic (3.48e-3)" "unprognostic (2.90e-1)" "unprognostic (6.98e-2)" "unprognostic (1.92e-5)" "unprognostic (8.36e-3)" "unprognostic (1.32e-1)" "unprognostic (3.15e-2)" "unprognostic (1.12e-3)" "unprognostic (1.65e-1)" "prognostic unfavorable (6.54e-4)" "unprognostic (1.00e-1)" "unprognostic (7.55e-2)" "unprognostic (1.74e-2)" "unprognostic (9.61e-2)" 22.6 17.5 19.6 19.9 22.0 16.7 15.6 17.4 35.8 36.9 13.2 13.1 8.1 26.5 9.9 29.8 20.8 21.4 13.6 33.1 19.3 40.7 6.5 26.2 14.3 28.6 20.2 26.4 101.4 7.3 15.1 44.9 23.0 15.6 8.5 19.4 8.4 18.5 30.0 21.6 15.2 20.0 17.5 22.5 9.3 25.3 22.9 11.6 31.0 14.0 14.6 14.6 23.1 26.7 4.6 18.1 11.1 5.8 9.2 6.5 64.7 4.2 9.1 6.2 7.2 55.0 0.8 4.4 9.5 8.0 40.8 2.8 11.0 2.5 3.7 393.5 12.1 140.5 19.3 23.0 16.0 1.8 93.0 8.1 4.0 17.8 0.5 25.3 34.8 6.1 75.0 0.5 3.6 4.4 2.1 5.4 8.3 4.0 3.2 9.1 61.5 3.2 25.1 3.3 17.1 11.3 22.3 5.1 6.0 29.4 0.7 7.5 32.5 1.8 8.2 5.1 3.0 0.5 0.1 0.1 1.8 7.9 10.5 0.0 1.0 3.8 0.3 2.1 0.3 0.4 0.1 0.2 0.5 0.1 0.1 0.1 1.1 0.9 1.1 0.0 0.5 0.4 19.6 22.0 17.4 35.8 33.1 19.3 28.6 20.2 23.0 17.5 22.9 26.7 19.7 6.4 3.4 33.6 4.1 3.1 3.6 3.1 1.8 11.8 1.9 2.3 1.2 1.5 11.9 14.7 73.0 19.2 4.9 7.1 3.9 2.0 33.4 24.0 21.6 9.1 6.6 0.4 26.2 5.3 21.0 8.2 3.6 50.3 0.0 10.8 11.7 1.3 6.7 10.1 50.2 2.2 0.0 8.3 6.9 47.7 1.5 9.0 8.8 27.2 10.4 5.7 4.1 53.3 49.2 2.1 7.1 2.2 2.8 1.6 6.7 3.2 14.9 25.8 0.0 5.3 4.8 2.6 6.1 11.3 6.0 19.4 5.7 8.4 1.2 6.2 L1TD1 "ECAT11, FLJ10884" ENSG00000240563 "LINE1 type transposase domain containing 1" Q5T7N2 1 62194849-62212328 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 5.5;intestine: 5.3;lymphoid tissue: 4.7;placenta: 11.6;testis: 5.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 110.2;Extravillous trophoblasts: 26.2;Intestinal goblet cells: 37.5;Spermatogonia: 53.1;Syncytiotrophoblasts: 28.2" "Cancer enriched" "Detected in some" 14 "testis cancer: 120.2" "Region enriched" "Detected in some" 4 "cerebellum: 5.5" "Immune cell enriched" "Detected in single" 13 "non-classical monocyte: 5.0" "Lineage enriched" "Detected in single" 21 "monocytes: 5.0" "Group enriched" "Detected in some" 22 "NTERA-2: 255.7;SuSa: 191.2" "Not detected" "Not detected" "HPA028501, HPA030064" Enhanced Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "HPA028501: AB_10599287, HPA030064: AB_10600538" "unprognostic (2.03e-2)" "unprognostic (7.88e-2)" "unprognostic (1.07e-1)" "unprognostic (1.86e-1)" "unprognostic (3.51e-1)" "unprognostic (2.29e-1)" "unprognostic (2.46e-1)" "unprognostic (4.03e-1)" "unprognostic (1.09e-1)" "unprognostic (9.23e-2)" "unprognostic (4.04e-2)" "unprognostic (4.61e-2)" "unprognostic (1.52e-5)" "unprognostic (3.49e-2)" "unprognostic (2.43e-1)" "unprognostic (5.75e-2)" "unprognostic (1.95e-1)" 0.2 0.3 0.1 4.7 0.5 0.0 0.2 5.5 1.3 0.3 0.0 5.3 0.1 0.1 0.3 0.0 0.1 0.2 0.0 0.3 0.0 0.3 0.0 1.5 0.2 0.2 0.1 0.2 0.0 0.0 0.1 11.6 0.3 0.1 1.2 0.0 0.4 0.1 0.0 0.1 0.3 0.3 0.0 0.9 0.1 5.8 0.0 0.2 0.4 0.0 0.1 0.1 0.2 0.6 0.0 0.0 0.2 0.1 0.0 0.0 10.1 0.1 0.0 1.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 255.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 191.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 5.0 0.0 0.0 0.0 0.1 0.5 5.5 1.3 0.3 0.0 0.2 0.1 0.3 0.0 0.0 0.6 0.5 6.4 13.0 0.0 1.8 0.4 0.7 0.1 0.0 2.5 1.0 2.2 0.3 0.0 7.5 0.0 6.2 110.2 2.1 3.6 0.0 0.0 0.5 0.8 0.5 2.3 10.7 0.0 0.6 0.4 26.2 3.6 0.0 1.7 1.3 2.2 0.0 0.1 7.6 3.3 0.4 37.5 0.0 1.4 1.2 1.0 1.8 4.3 0.0 0.0 0.5 0.4 1.0 0.0 0.1 0.3 1.6 18.4 1.1 0.6 0.1 0.1 6.0 3.7 0.0 1.1 2.7 0.7 53.1 0.0 0.1 28.2 1.9 2.3 9.2 0.3 L3HYPDH "C14orf149, FLJ25436" ENSG00000126790 "Trans-L-3-hydroxyproline dehydratase" Q96EM0 14 59460363-59484408 "Enzymes, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 47.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056694 Approved Uncertain Vesicles NA NA 49000 "Cluster 48: NK-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA056694: AB_2683210" "unprognostic (3.39e-2)" "unprognostic (5.55e-3)" "unprognostic (3.81e-2)" "unprognostic (5.86e-2)" "unprognostic (1.10e-1)" "unprognostic (5.06e-2)" "unprognostic (8.34e-2)" "unprognostic (1.16e-1)" "unprognostic (7.24e-2)" "unprognostic (9.50e-2)" "unprognostic (1.26e-3)" "unprognostic (6.60e-2)" "prognostic unfavorable (1.72e-9)" "unprognostic (1.16e-1)" "unprognostic (2.22e-1)" "unprognostic (1.05e-1)" "unprognostic (1.14e-1)" 18.1 14.0 4.8 12.5 5.2 4.8 16.3 9.9 6.6 15.9 10.0 10.6 11.0 16.0 8.5 9.2 15.4 11.5 14.8 5.0 5.8 17.4 17.3 11.2 17.5 7.9 5.8 18.0 12.6 12.2 14.8 10.4 7.4 13.5 10.2 5.2 13.0 11.9 8.9 9.7 13.8 11.9 5.6 13.0 10.5 17.1 4.8 4.3 16.6 5.6 13.7 13.4 14.5 8.3 12.0 31.8 6.8 16.2 14.4 37.6 9.5 31.7 25.1 17.9 17.4 6.4 21.1 4.1 13.0 17.7 31.8 31.8 11.1 17.0 17.7 7.0 14.4 11.0 30.1 23.7 16.2 10.0 7.6 27.3 11.4 18.0 27.6 27.8 22.3 11.3 14.8 18.4 18.8 14.3 3.8 16.4 10.9 4.7 28.5 5.5 11.1 16.6 28.7 6.8 6.9 9.9 29.8 12.2 11.9 5.6 12.8 6.4 31.3 20.9 25.6 16.4 37.5 4.7 2.3 4.0 35.9 8.3 41.7 0.0 3.5 0.5 3.2 5.1 2.4 1.5 1.7 2.0 5.7 1.4 2.5 0.9 0.0 5.6 2.4 3.2 0.8 1.8 4.8 5.2 9.9 6.6 5.0 5.8 7.9 5.8 7.4 5.6 4.8 8.3 11.2 3.2 6.1 11.1 10.9 5.2 5.4 4.2 6.2 2.9 5.6 8.6 8.7 5.7 4.3 3.7 2.1 13.7 3.5 1.0 7.9 7.7 12.2 6.8 17.5 8.1 3.0 5.5 26.7 2.5 11.4 16.0 4.6 2.3 14.0 6.5 11.0 16.8 8.3 1.7 18.9 4.3 4.1 4.6 2.9 7.4 19.3 4.9 3.6 10.3 3.5 4.6 4.1 10.6 17.1 4.4 1.0 12.0 5.5 6.6 3.4 47.0 17.3 2.7 13.1 17.4 11.6 14.1 5.7 7.5 3.4 4.9 6.0 11.9 3.5 2.0 L3MBTL4 "FLJ35936, HsT1031" ENSG00000154655 "L3MBTL histone methyl-lysine binding protein 4" Q8NA19 18 5954706-6415237 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 160.4;Late spermatids: 85.8;Microglial cells: 78.7;Oligodendrocyte precursor cells: 191.5;Oligodendrocytes: 252.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "NK-cell: 3.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "GAMG: 3.4;Karpas-707: 4.8;RPMI-8226: 11.6;SCLC-21H: 5.3;SH-SY5Y: 5.8;U-2 OS: 3.4" "Low region specificity" "Detected in some" "HPA064194, HPA069042" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Vesicles" "HPA064194: AB_2685208, HPA069042: AB_2686071" "unprognostic (1.33e-3)" "unprognostic (8.98e-2)" "unprognostic (6.31e-2)" "unprognostic (1.10e-1)" "unprognostic (3.56e-2)" "unprognostic (1.40e-1)" "unprognostic (1.70e-2)" "unprognostic (1.73e-1)" "unprognostic (4.68e-2)" "unprognostic (1.94e-1)" "unprognostic (1.92e-1)" "unprognostic (1.91e-1)" "unprognostic (1.20e-2)" "unprognostic (5.08e-2)" "unprognostic (1.00e-1)" "unprognostic (2.14e-3)" "unprognostic (6.08e-2)" 3.0 4.3 7.1 1.8 11.5 1.6 4.9 0.2 8.4 4.3 0.6 2.1 3.0 3.2 3.6 3.6 4.2 2.5 4.9 3.8 6.8 7.1 8.8 3.9 2.0 3.3 8.2 8.5 6.5 8.5 3.2 0.7 4.7 2.0 2.0 1.7 3.4 2.9 1.0 7.3 3.5 1.3 1.6 2.9 3.2 12.7 6.6 2.9 5.8 1.3 1.6 1.4 4.1 14.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.5 0.0 0.0 3.4 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.1 2.4 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.2 0.0 1.4 3.1 0.0 11.6 0.0 2.0 5.3 5.8 0.0 0.0 0.2 0.3 0.0 0.0 0.1 0.0 3.4 0.1 1.4 0.1 0.0 0.0 1.3 0.0 1.7 0.3 1.1 0.0 0.7 0.3 0.0 0.5 0.1 0.1 0.7 2.5 0.1 0.2 0.1 3.6 0.8 0.1 0.0 0.5 7.1 11.5 0.2 8.4 3.8 6.8 3.3 8.2 4.7 1.6 6.6 14.0 6.5 3.2 12.2 56.2 4.8 7.8 7.0 0.8 10.2 2.2 4.5 4.8 6.4 11.5 4.1 5.5 16.7 0.1 2.7 0.3 3.9 7.4 62.5 8.1 1.2 3.6 11.4 0.8 33.9 5.2 0.0 3.4 1.5 16.9 1.3 15.4 2.5 10.0 3.2 0.0 160.4 1.5 0.0 3.2 5.3 85.8 10.2 2.9 1.8 78.7 27.2 1.8 25.7 191.5 252.9 3.5 1.9 12.8 1.5 10.3 3.5 8.1 1.2 0.6 6.6 6.9 7.2 9.3 2.4 6.5 8.2 0.1 2.1 0.5 2.5 4.6 LAMA5 ENSG00000130702 "Laminin subunit alpha 5" O15230 20 62307955-62367312 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Cytotrophoblasts: 104.4;Glandular and luminal cells: 82.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 114.9;CACO-2: 159.6;EFO-21: 114.4;HaCaT: 107.2;HeLa: 118.3;TIME: 138.4" "Low region specificity" "Detected in many" "HPA058389, CAB078157" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 1800000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "CAB078157: AB_2665809, HPA058389: " "unprognostic (8.01e-2)" "unprognostic (2.47e-1)" "unprognostic (1.92e-2)" "unprognostic (3.42e-3)" "unprognostic (1.17e-1)" "unprognostic (9.90e-3)" "unprognostic (4.01e-3)" "unprognostic (5.45e-2)" "unprognostic (8.99e-2)" "unprognostic (1.34e-2)" "unprognostic (5.98e-3)" "unprognostic (2.98e-3)" "unprognostic (4.04e-2)" "unprognostic (9.86e-3)" "unprognostic (2.07e-1)" "unprognostic (9.76e-2)" "unprognostic (1.33e-2)" 27.1 11.8 4.7 5.0 2.2 1.3 27.0 15.2 7.0 26.3 18.9 66.7 5.3 31.3 1.2 24.5 31.8 7.9 26.6 2.4 2.0 32.7 13.2 43.9 3.0 3.2 1.9 9.3 13.9 4.8 12.1 20.0 2.5 36.7 1.2 0.6 17.8 15.4 11.0 36.0 19.9 7.3 0.6 14.0 25.1 4.6 9.3 2.7 28.6 2.8 1.9 32.6 30.2 0.4 15.1 114.9 2.2 14.8 2.7 31.0 85.9 4.2 2.2 3.3 0.6 159.6 59.1 1.3 114.4 0.1 3.6 107.2 3.1 45.8 0.2 0.3 6.5 3.8 118.3 46.1 9.9 0.0 16.6 1.6 29.6 7.9 8.0 5.7 15.0 0.0 7.0 1.7 0.0 22.3 0.1 0.4 7.3 19.3 65.9 0.2 1.4 12.8 28.6 70.3 1.1 44.5 63.2 62.2 1.2 11.6 62.0 0.9 138.4 1.6 41.2 0.7 18.9 0.8 0.2 0.6 31.7 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.7 2.2 15.2 7.0 2.4 2.0 3.2 1.9 2.5 0.6 9.3 0.4 60.2 76.9 37.1 19.9 6.9 17.1 16.0 56.8 52.9 3.6 16.7 20.8 20.5 12.8 43.9 38.6 8.4 104.4 3.9 0.6 0.0 28.6 4.3 35.5 11.7 49.6 2.4 6.1 5.9 4.5 23.3 13.0 6.1 82.0 2.5 0.9 18.9 12.7 13.1 3.3 12.7 0.3 14.2 0.6 5.4 1.3 9.9 2.2 1.8 10.3 1.1 8.2 1.0 3.5 1.3 13.2 0.1 19.5 8.5 21.9 0.0 12.2 49.6 1.8 26.3 11.0 39.4 0.6 1.7 23.4 12.6 57.3 2.2 1.7 0.6 27.5 LAMB2 "LAMS, NPHS5" ENSG00000172037 "Laminin subunit beta 2" P55268 3 49121114-49133118 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 151.8;Leydig cells: 146.3;Peritubular cells: 140.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 299.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000053, HPA001895, HPA050033, CAB078160" Supported Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA 25000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Cytosol "CAB000053: AB_2313665, CAB078160: AB_2665799, HPA001895: AB_1079227, HPA050033: " "unprognostic (1.12e-2)" "unprognostic (4.40e-2)" "unprognostic (5.14e-3)" "unprognostic (1.10e-1)" "unprognostic (4.08e-1)" "unprognostic (4.01e-1)" "unprognostic (5.59e-2)" "unprognostic (6.80e-2)" "unprognostic (1.24e-1)" "unprognostic (1.82e-2)" "unprognostic (1.26e-1)" "unprognostic (4.96e-2)" "unprognostic (1.21e-3)" "unprognostic (1.78e-1)" "unprognostic (4.38e-2)" "unprognostic (6.20e-2)" "unprognostic (1.24e-2)" 75.2 73.2 12.8 18.2 14.2 2.6 58.2 15.1 14.9 68.0 47.7 63.1 24.6 72.7 25.5 31.9 63.8 62.2 169.1 13.1 14.5 41.3 31.7 55.1 16.9 20.0 14.8 94.4 32.7 104.7 15.4 99.0 15.4 50.4 18.0 11.7 40.3 81.0 67.5 40.9 32.5 80.2 14.1 29.8 48.4 21.4 17.3 6.7 60.2 70.0 12.8 52.2 55.9 13.5 15.7 38.7 34.4 122.0 196.3 201.5 31.1 131.9 161.8 73.8 75.7 18.3 52.0 0.2 44.4 299.0 38.3 49.3 30.0 47.6 52.3 0.1 9.5 6.9 63.4 32.1 132.5 0.3 0.3 176.9 69.4 61.6 62.1 184.3 75.9 0.0 4.1 0.1 61.4 30.3 0.1 0.3 15.1 20.7 32.0 0.2 16.6 0.5 53.5 19.1 0.2 20.4 74.9 42.9 68.3 57.5 93.4 0.9 126.9 82.2 34.9 28.5 35.4 0.1 0.4 0.4 39.1 0.3 57.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.8 14.2 15.1 14.9 13.1 14.5 20.0 14.8 15.4 14.1 17.3 13.5 83.7 118.6 53.5 26.1 2.4 31.2 13.9 33.6 33.0 1.7 39.4 40.5 151.8 37.1 43.6 55.2 6.2 11.3 0.9 3.6 5.9 26.4 3.5 15.4 24.4 77.8 0.0 0.4 0.2 9.4 6.4 120.1 50.4 27.2 1.3 88.9 94.9 49.9 10.4 8.4 0.4 3.1 32.6 10.1 31.1 12.3 146.3 7.5 42.7 15.9 3.5 46.7 2.1 1.0 0.6 14.1 14.9 140.7 0.5 10.2 16.4 28.6 11.2 2.6 118.3 80.8 92.3 4.3 8.6 14.2 24.4 9.4 3.8 27.6 5.6 9.3 LAMB3 "BM600-125kDa, kalinin-140kDa, LAMNB1, nicein-125kDa" ENSG00000196878 "Laminin subunit beta 3" Q13751 1 209614870-209652425 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Amelogenesis imperfecta, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 73.2;urinary bladder: 73.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 370.0;Basal respiratory cells: 447.6;Pancreatic endocrine cells: 853.8;Urothelial cells: 392.7" "Cancer enhanced" "Detected in all" "head and neck cancer: 223.9" "Region enriched" "Detected in many" 7 "cerebral cortex: 21.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 353.8;HaCaT: 538.2;HBEC3-KT: 1315.0;hTCEpi: 412.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA007584, HPA008069, CAB078183" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 20000 "Cluster 1: Neutrophils - Mixed function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "CAB078183: AB_2665825, HPA007584: , HPA008069: AB_1079228" "prognostic favorable (8.43e-4)" "unprognostic (3.08e-2)" "unprognostic (1.46e-2)" "unprognostic (2.88e-2)" "unprognostic (8.00e-2)" "unprognostic (1.60e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.62e-5)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" "prognostic unfavorable (2.55e-4)" "unprognostic (1.31e-1)" "prognostic unfavorable (2.43e-5)" "unprognostic (1.02e-1)" "unprognostic (2.38e-1)" "unprognostic (6.01e-2)" "unprognostic (4.92e-3)" 10.9 16.0 2.6 13.1 2.9 10.7 20.7 0.9 21.3 13.2 0.5 26.2 31.5 18.0 2.6 47.2 16.4 11.9 6.8 2.9 2.1 16.3 9.3 28.4 1.2 1.5 1.5 1.1 4.2 0.1 1.7 5.8 1.6 25.9 16.6 0.2 41.5 24.1 6.8 42.1 43.7 2.3 1.7 1.0 73.2 1.0 1.9 5.8 1.2 0.3 13.2 73.1 32.6 2.8 178.4 25.8 0.0 0.4 18.1 11.7 1.0 5.1 15.4 6.0 9.1 68.9 353.8 0.1 15.1 3.7 8.9 538.2 0.1 1315.0 9.1 13.1 1.4 1.1 86.9 1.1 2.4 1.0 1.3 2.6 412.8 19.1 253.4 11.7 6.4 0.1 2.5 6.7 1.9 0.3 0.2 1.2 0.6 81.0 74.0 0.2 17.1 165.4 70.9 109.0 0.5 0.5 73.9 8.5 15.4 1.0 2.0 9.7 138.3 29.1 61.3 1.0 104.6 1.7 3.4 0.4 42.2 0.8 2.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 2.6 2.9 0.9 21.3 2.9 2.1 1.5 1.5 1.6 1.7 1.9 2.8 0.4 221.2 67.7 1.6 1.2 109.7 370.0 447.6 159.9 0.3 11.5 64.4 8.4 4.3 168.5 47.8 0.0 1.1 0.4 247.5 0.0 180.5 6.0 50.8 10.0 3.5 7.8 0.4 2.5 153.0 1.4 7.5 195.7 135.0 18.4 0.2 0.4 3.9 2.0 3.3 2.3 71.7 18.3 0.3 30.0 10.9 1.8 9.9 8.8 0.0 2.1 0.4 0.0 1.0 1.7 853.8 229.1 0.7 2.1 185.0 111.9 2.3 52.2 0.3 0.0 5.3 10.4 0.3 0.6 51.7 26.0 0.5 4.0 0.0 63.1 392.7 LAMP2 CD107b ENSG00000005893 "Lysosomal associated membrane protein 2" P13473 X 120426148-120469365 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Autophagy "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 507.2;Syncytiotrophoblasts: 402.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 556.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 556.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005272, HPA029100" Supported Supported Vesicles NA NA 520000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "CAB005272: AB_647855, HPA029100: AB_10795022" "unprognostic (2.99e-3)" "unprognostic (5.26e-2)" "unprognostic (2.66e-3)" "unprognostic (1.74e-1)" "unprognostic (3.10e-1)" "unprognostic (2.50e-2)" "unprognostic (4.84e-1)" "unprognostic (1.56e-1)" "unprognostic (1.15e-1)" "unprognostic (1.55e-1)" "unprognostic (9.73e-2)" "unprognostic (1.11e-2)" "unprognostic (2.50e-2)" "unprognostic (2.85e-1)" "unprognostic (6.78e-2)" "unprognostic (2.66e-1)" "unprognostic (5.53e-3)" 54.2 68.7 80.3 38.3 144.2 62.8 56.3 109.1 135.5 64.9 52.7 39.2 44.3 44.3 55.1 79.4 44.1 69.6 45.3 81.6 101.8 85.5 129.9 54.2 34.1 113.0 112.6 49.1 57.8 64.2 32.2 47.9 120.6 62.2 35.0 32.6 102.1 55.1 111.6 67.2 42.4 42.8 100.5 39.5 51.8 26.2 100.9 59.3 61.7 67.4 36.6 43.4 63.3 211.7 53.8 47.5 40.1 49.7 367.0 140.9 91.5 79.3 130.4 77.1 134.4 42.7 90.3 47.9 73.1 132.7 236.2 84.9 56.7 67.2 125.5 43.6 37.2 35.8 46.4 54.3 148.1 158.9 73.2 151.5 114.8 108.1 75.1 188.6 107.5 32.5 42.1 122.9 117.2 79.3 45.3 80.2 29.0 63.7 42.6 35.1 65.3 73.1 102.3 36.9 14.0 22.6 99.7 93.0 196.5 57.4 64.7 173.0 122.5 114.1 58.7 176.2 261.5 68.5 78.6 30.2 131.4 182.4 284.4 30.6 114.9 224.1 27.1 97.1 20.6 17.1 24.3 24.5 64.2 22.5 23.4 21.8 556.6 31.8 96.2 33.4 33.4 66.3 80.3 144.2 109.1 135.5 81.6 101.8 113.0 112.6 120.6 100.5 100.9 211.7 75.7 73.7 53.8 52.2 29.8 100.9 92.5 262.7 64.9 17.6 74.0 58.3 37.3 173.0 155.3 66.2 14.6 163.7 44.3 52.1 39.2 217.7 3.3 103.4 74.1 69.9 36.6 14.1 32.4 70.6 128.3 113.7 38.7 168.1 17.7 46.7 87.8 176.8 208.0 18.5 40.7 32.6 134.3 133.1 80.4 8.6 113.7 135.5 131.6 33.7 132.7 116.3 50.4 57.3 507.2 62.5 54.4 109.9 66.6 100.8 97.5 154.7 75.6 11.5 39.5 176.8 61.7 6.4 13.7 78.8 136.2 402.4 34.5 71.0 34.8 92.9 LAMP3 "CD208, DC-LAMP, DCLAMP, LAMP, TSC403" ENSG00000078081 "Lysosomal associated membrane protein 3" Q9UQV4 3 183122215-183163839 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "lung: 219.7" "Group enriched" "Detected in many" 4 "Alveolar cells type 2: 486.7;monocytes: 339.6" "Cancer enhanced" "Detected in many" "lung cancer: 27.6" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "eosinophil: 5.6" "Group enriched" "Detected in many" 8 "granulocytes: 5.6;T-cells: 4.8" "Group enriched" "Detected in many" 4 "EFO-21: 169.5;HDLM-2: 46.6;HHSteC: 60.4;hTCEpi: 59.1;JURKAT: 52.7" "CAB025133, HPA051467" Enhanced Enhanced Vesicles NA NA 59000 "Cluster 13: T-cells - Unknown function" "Cluster 19: Lung - Lung function" "Cluster 38: EFO-21 - Unknown function" "Cluster 3: Monocytes - Immune response regulation" Vesicles "CAB025133: , HPA051467: AB_2681495" "unprognostic (1.43e-3)" "unprognostic (2.06e-2)" "unprognostic (1.70e-1)" "unprognostic (2.99e-3)" "unprognostic (1.30e-2)" "unprognostic (2.15e-1)" "unprognostic (7.67e-2)" "unprognostic (8.64e-2)" "unprognostic (4.95e-2)" "prognostic favorable (9.90e-4)" "unprognostic (1.80e-3)" "unprognostic (5.80e-2)" "prognostic unfavorable (1.89e-7)" "unprognostic (3.12e-1)" "unprognostic (4.13e-2)" "unprognostic (8.35e-2)" "unprognostic (1.29e-1)" 0.7 0.6 0.2 33.1 0.4 0.8 1.3 0.3 0.2 1.4 0.0 3.2 2.7 0.7 2.6 4.4 1.1 3.9 0.3 0.2 0.1 0.6 0.9 219.7 16.1 0.2 0.1 0.3 7.8 1.9 0.5 1.9 0.1 2.7 6.8 0.6 27.2 2.5 0.2 7.0 3.1 4.3 0.2 9.0 4.1 22.7 0.3 28.1 7.5 0.2 21.5 11.2 0.9 0.0 10.7 0.3 0.2 1.7 0.1 0.1 8.7 0.2 2.8 1.8 0.5 2.8 5.3 0.1 169.5 0.9 18.9 1.5 3.7 6.4 0.2 46.6 5.9 0.0 0.3 0.4 60.4 0.0 1.4 0.9 59.1 0.1 7.4 0.0 7.6 52.7 0.4 9.9 0.2 0.2 2.5 0.4 0.3 0.9 2.7 0.0 0.0 0.8 0.2 3.4 0.7 0.4 0.8 0.3 5.0 2.1 3.4 0.4 8.3 0.0 3.0 0.4 0.2 3.5 13.2 0.5 0.0 0.1 0.1 0.3 0.0 5.6 0.2 0.0 2.4 0.1 1.8 1.1 0.0 0.2 2.3 1.3 1.3 0.6 0.0 0.0 4.8 0.7 0.2 0.4 0.3 0.2 0.2 0.1 0.2 0.1 0.1 0.2 0.3 0.0 0.2 64.1 486.7 0.0 2.0 6.0 2.9 2.4 8.6 0.0 0.3 0.6 1.2 1.5 9.5 1.8 0.0 2.9 0.1 0.1 0.0 0.6 34.3 1.3 0.2 0.5 0.0 0.4 0.7 6.1 0.4 1.0 1.5 0.8 18.9 0.4 0.0 0.0 1.3 0.0 0.6 0.2 0.0 0.0 41.1 84.9 0.6 4.8 1.8 0.0 339.6 0.0 0.0 0.0 0.1 0.6 0.0 0.0 4.1 1.6 0.1 0.0 11.5 0.0 0.0 0.4 0.3 14.0 0.5 4.0 5.7 1.2 2.3 0.0 0.5 2.2 LAMTOR1 "C11orf59, FLJ20625, p18, p27RF-Rho, Pdro, Ragulator1" ENSG00000149357 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1" Q6IAA8 11 72085895-72103297 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002997 Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA 160000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 51: Myeloid cells - Hemostasis" "Golgi apparatus" "Vesicles, Plasma membrane" "HPA002997: AB_1845531" "unprognostic (7.32e-2)" "unprognostic (1.79e-1)" "unprognostic (3.94e-2)" "unprognostic (3.77e-2)" "unprognostic (2.30e-1)" "unprognostic (2.71e-2)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.00e-1)" "unprognostic (2.18e-1)" "unprognostic (1.94e-1)" "unprognostic (5.45e-2)" "unprognostic (2.10e-3)" "unprognostic (1.78e-3)" "unprognostic (3.08e-1)" "unprognostic (2.46e-1)" "unprognostic (1.00e-1)" "unprognostic (1.04e-1)" 100.7 143.8 171.2 69.1 177.8 118.6 96.2 173.2 180.4 87.0 162.1 88.6 67.5 86.5 90.0 114.1 74.9 65.8 131.9 163.5 169.5 129.5 114.2 91.3 80.6 177.4 177.2 81.5 85.6 87.0 92.0 67.4 174.9 102.4 76.5 46.6 85.8 71.7 126.4 89.9 82.5 73.7 175.4 130.9 96.6 41.2 176.1 75.4 112.3 109.3 79.4 88.5 77.9 172.5 94.2 181.0 97.3 132.0 224.7 152.3 97.6 129.0 201.6 206.2 151.7 230.9 139.7 93.1 162.3 216.9 214.2 138.1 171.1 260.1 155.8 117.8 99.3 245.6 108.5 156.5 291.4 97.2 147.7 252.3 199.2 224.4 224.0 116.4 173.1 102.5 104.1 96.0 211.4 295.6 86.2 146.1 93.9 291.8 194.9 73.7 178.9 78.8 246.8 195.1 65.7 103.3 127.6 127.5 343.7 106.4 192.6 93.2 125.3 137.5 98.0 323.8 93.0 111.6 139.0 80.4 81.8 81.8 113.0 113.4 414.3 274.1 80.6 228.8 77.7 132.1 75.6 81.1 332.6 146.2 63.4 77.9 229.5 122.8 180.6 197.1 98.8 397.5 171.2 177.8 173.2 180.4 163.5 169.5 177.4 177.2 174.9 175.4 176.1 172.5 132.6 44.8 71.6 9.1 109.7 55.7 161.7 271.1 117.8 58.5 159.9 195.7 66.4 121.5 120.2 128.8 12.5 266.5 110.7 235.4 295.4 276.4 12.4 61.2 98.9 134.9 116.4 133.5 9.8 340.2 300.1 111.6 71.4 85.2 97.7 71.5 142.1 86.9 468.0 77.4 12.9 140.2 170.9 248.5 111.6 19.2 107.8 311.5 113.8 8.4 413.6 223.7 177.1 10.1 24.2 307.3 202.6 102.7 87.9 193.4 230.3 370.9 61.0 56.1 111.7 102.5 116.3 58.7 103.3 126.1 55.4 282.0 89.4 178.5 170.8 157.2 LAMTOR2 "ENDAP, MAPBPIP, MAPKSP1AP, p14, Ragulator2, ROBLD3" ENSG00000116586 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2" Q9Y2Q5 1 156054782-156058506 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 627.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004126 Approved Approved Nucleoplasm,Vesicles No No "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Vesicles" "HPA004126: AB_1849916" "unprognostic (2.09e-1)" "unprognostic (1.23e-1)" "unprognostic (2.07e-1)" "unprognostic (1.58e-1)" "unprognostic (8.14e-2)" "unprognostic (4.52e-2)" "unprognostic (8.64e-2)" "unprognostic (3.90e-2)" "unprognostic (3.79e-1)" "unprognostic (1.66e-2)" "unprognostic (2.06e-1)" "unprognostic (3.41e-2)" "prognostic unfavorable (1.10e-6)" "unprognostic (2.47e-1)" "unprognostic (1.34e-1)" "unprognostic (8.65e-2)" "unprognostic (1.35e-1)" 64.3 84.4 81.9 41.6 81.4 57.1 57.7 83.9 98.9 44.8 83.0 62.0 51.5 42.3 76.7 75.2 52.1 43.8 96.1 81.6 84.7 91.0 164.3 53.8 56.3 81.6 82.5 26.7 87.8 74.4 44.6 37.5 82.0 50.9 56.5 18.0 59.3 44.0 88.6 57.8 53.7 48.9 82.2 65.7 78.1 26.6 85.8 56.1 44.7 70.2 52.0 53.6 46.7 85.8 63.9 142.3 65.4 90.9 131.9 106.7 72.3 55.7 94.4 68.8 78.1 65.9 106.1 94.0 94.4 108.7 60.0 91.5 67.7 151.1 38.7 78.4 103.0 54.9 96.2 88.6 104.4 78.0 86.5 126.1 93.4 73.1 93.3 94.4 142.6 137.3 50.8 68.1 100.9 128.7 80.6 111.4 69.4 250.9 212.1 67.5 48.7 138.7 152.5 93.2 25.3 145.3 70.4 195.1 116.3 104.1 136.5 227.9 96.6 57.5 52.4 83.4 53.0 101.6 166.5 56.2 102.2 87.3 62.9 281.8 465.8 376.2 172.2 446.9 169.8 290.6 188.2 188.7 537.2 249.4 142.6 152.8 231.8 207.0 363.2 284.1 298.3 389.7 81.9 81.4 83.9 98.9 81.6 84.7 81.6 82.5 82.0 82.2 85.8 85.8 102.5 57.7 46.5 3.6 64.5 48.4 59.5 190.3 43.3 29.4 129.9 123.2 113.5 114.4 120.2 108.5 6.2 146.3 73.9 247.5 387.4 193.0 44.5 113.2 78.7 92.6 126.1 48.0 4.5 179.3 203.1 67.5 68.3 105.0 107.3 56.7 86.7 322.1 416.1 6.7 5.4 164.7 197.4 188.9 150.1 89.0 47.2 165.0 158.3 5.6 297.4 92.8 94.7 4.5 5.8 183.2 267.4 50.8 76.8 80.2 317.8 627.2 144.1 30.5 32.9 38.9 124.6 25.5 33.9 99.4 80.0 77.2 64.2 83.3 166.9 97.7 LAMTOR4 C7orf59 ENSG00000188186 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 4" Q0VGL1 7 100148907-100155944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 3294.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020998 Enhanced Supported Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA020998: AB_1845762" "prognostic favorable (2.48e-4)" "prognostic favorable (6.08e-4)" "unprognostic (1.29e-2)" "unprognostic (1.14e-1)" "unprognostic (8.21e-3)" "unprognostic (6.11e-2)" "unprognostic (1.10e-2)" "unprognostic (1.32e-2)" "unprognostic (6.17e-2)" "unprognostic (1.57e-1)" "unprognostic (2.42e-3)" "unprognostic (8.83e-2)" "unprognostic (1.11e-1)" "unprognostic (1.80e-1)" "unprognostic (2.68e-1)" "unprognostic (2.45e-1)" "unprognostic (1.68e-2)" 145.5 144.7 207.2 92.8 215.4 194.6 143.4 221.1 260.4 148.0 204.4 180.6 89.4 116.7 65.9 117.5 123.1 97.7 167.4 205.7 212.3 188.5 139.1 128.0 159.0 222.1 211.3 142.7 124.2 126.7 162.7 68.1 213.3 160.8 105.8 39.9 116.8 76.2 137.5 478.7 151.0 69.0 217.6 251.9 162.2 86.6 215.8 104.8 133.8 106.0 85.5 145.8 126.7 224.1 105.9 250.9 130.2 165.4 135.2 154.9 105.7 62.1 151.0 113.1 138.9 116.9 165.7 169.1 204.7 94.2 205.7 108.9 124.0 160.0 48.1 172.4 353.2 135.2 245.0 205.4 127.4 106.4 187.1 187.3 155.4 118.5 145.6 125.7 174.9 155.3 129.9 264.4 156.1 501.0 104.0 424.7 138.7 291.1 199.9 107.4 107.1 302.8 129.1 126.9 91.6 169.0 114.3 265.8 211.3 99.0 107.1 207.0 118.3 107.1 158.6 223.7 101.7 159.1 231.2 324.2 171.0 293.5 155.9 1033.3 843.2 3121.0 299.6 795.1 251.1 541.8 377.5 312.8 570.0 475.4 381.8 307.2 3294.2 310.1 756.2 482.6 453.0 893.6 207.2 215.4 221.1 260.4 205.7 212.3 222.1 211.3 213.3 217.6 215.8 224.1 181.8 93.0 150.7 18.9 195.8 274.9 194.0 282.0 167.9 65.3 240.8 277.2 176.6 143.0 172.9 218.8 12.5 258.4 199.9 819.7 534.1 167.3 40.0 152.9 125.8 186.7 299.3 99.3 12.0 326.2 196.5 175.6 146.3 131.4 183.2 120.9 239.1 246.3 531.1 58.9 13.6 423.9 252.3 497.4 351.7 46.6 146.3 365.2 434.0 13.1 411.0 229.9 298.6 11.6 26.2 204.2 867.4 120.4 133.0 169.5 511.6 557.5 194.8 67.0 144.7 142.1 196.9 88.1 101.2 151.3 662.9 201.4 195.9 150.8 511.8 219.0 LAPTM4A "HUMORF13, KIAA0108, LAPTM4, MBNT, Mtrp" ENSG00000068697 "Lysosomal protein transmembrane 4 alpha" Q15012 2 20032650-20051628 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 1393.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031402, HPA031404, HPA068554" Approved Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus, Vesicles" "Plasma membrane" "HPA031402: AB_10669882, HPA031404: AB_10670293, HPA068554: AB_2686003" "unprognostic (2.01e-1)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (5.73e-1)" "unprognostic (6.04e-2)" "unprognostic (3.00e-2)" "unprognostic (1.53e-3)" "unprognostic (5.37e-2)" "unprognostic (1.27e-1)" "unprognostic (3.65e-2)" "prognostic unfavorable (4.37e-4)" "unprognostic (8.70e-2)" "unprognostic (1.05e-2)" "unprognostic (7.78e-3)" "unprognostic (2.18e-2)" "unprognostic (7.98e-3)" "unprognostic (2.36e-1)" 360.5 451.0 116.8 177.1 114.9 199.5 338.5 120.7 146.8 469.8 150.8 256.2 219.6 507.6 339.7 315.4 370.1 383.7 322.5 112.7 130.2 460.9 409.2 308.0 160.1 123.3 122.2 460.3 290.8 289.2 155.6 397.6 128.1 306.3 233.9 59.1 306.0 611.8 204.4 247.2 227.7 412.2 130.1 190.9 240.5 389.3 125.5 122.8 365.8 234.8 178.5 342.1 248.7 128.0 417.7 228.8 136.4 283.2 1393.4 1031.8 509.1 514.3 651.8 349.3 393.6 180.5 398.4 73.2 116.2 637.9 356.9 400.7 115.0 250.6 317.8 181.2 183.2 112.4 244.3 520.1 534.8 86.7 294.9 691.7 501.2 338.7 386.4 481.9 367.6 62.2 86.6 135.8 527.5 243.3 53.8 114.0 299.2 353.1 207.1 89.3 397.5 139.7 858.6 347.7 214.8 207.3 480.4 390.5 335.9 492.9 169.6 70.1 467.5 575.7 203.8 500.3 336.5 221.7 349.2 118.3 455.3 172.8 234.4 737.8 382.3 289.3 94.6 324.9 116.4 197.4 112.9 106.9 269.2 192.3 126.7 113.7 200.1 124.3 393.4 226.9 119.3 427.0 116.8 114.9 120.7 146.8 112.7 130.2 123.3 122.2 128.1 130.1 125.5 128.0 351.7 195.5 203.1 39.2 156.5 659.0 601.1 1210.5 339.2 24.4 330.3 306.1 211.7 380.3 727.7 553.6 12.5 224.4 109.8 174.8 162.4 539.4 1235.7 195.7 407.1 384.0 138.1 65.0 15.0 347.6 1035.3 896.8 111.6 286.0 521.9 445.7 331.3 519.4 311.3 20.2 14.3 203.6 767.0 299.3 716.0 1080.9 835.3 254.4 588.7 39.4 278.0 315.3 48.4 34.7 18.7 289.4 246.2 600.7 156.8 331.2 171.5 940.9 506.7 24.7 532.5 389.4 583.0 356.3 173.5 268.2 709.8 302.9 146.4 579.1 224.8 500.9 LBH ENSG00000213626 "LBH regulator of WNT signaling pathway" Q53QV2 2 30231534-30323730 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 210.6;Pancreatic endocrine cells: 298.9;Smooth muscle cells: 435.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 112.4;MAIT T-cell: 110.2;memory B-cell: 92.0;memory CD4 T-cell: 83.8;memory CD8 T-cell: 86.1;naive B-cell: 123.0;naive CD4 T-cell: 140.2;naive CD8 T-cell: 124.6;T-reg: 89.2" "Group enriched" "Detected in all" 7 "B-cells: 123.0;T-cells: 140.2" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 302.4;hTERT-RPE1: 150.6;U-2 OS: 95.1" "Low region specificity" "Detected in all" HPA034669 Approved Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA034669: AB_10600820" "unprognostic (2.13e-2)" "unprognostic (2.34e-2)" "unprognostic (1.78e-1)" "unprognostic (4.77e-3)" "unprognostic (1.23e-3)" "unprognostic (1.57e-1)" "unprognostic (2.69e-1)" "unprognostic (3.65e-3)" "unprognostic (1.93e-1)" "unprognostic (3.24e-2)" "unprognostic (2.54e-1)" "unprognostic (1.60e-1)" "unprognostic (2.32e-2)" "prognostic unfavorable (8.24e-4)" "unprognostic (2.25e-2)" "unprognostic (7.91e-3)" "unprognostic (1.67e-1)" 35.2 10.3 8.4 57.4 7.9 28.6 32.0 13.7 22.4 45.6 18.4 27.4 14.4 83.0 27.0 17.0 41.7 44.9 119.3 15.2 33.9 39.3 15.0 130.7 117.8 23.0 17.4 63.3 14.4 84.8 16.7 54.5 18.4 27.3 18.1 70.8 63.9 26.3 14.3 30.3 41.2 48.2 11.2 83.5 22.8 9.8 14.4 125.7 68.9 20.4 100.9 35.5 22.7 11.8 0.1 11.4 14.0 2.5 3.6 2.2 1.1 14.5 19.1 3.8 0.6 59.4 15.2 28.6 33.3 302.4 3.8 19.5 81.1 0.8 0.6 41.3 3.4 4.6 12.2 0.2 10.9 0.4 4.0 13.0 1.1 5.0 0.3 150.6 0.7 19.0 14.6 0.2 14.2 0.2 32.3 0.4 84.6 2.6 0.6 33.1 75.4 9.7 2.6 5.0 3.9 10.0 23.7 2.3 1.0 49.7 0.1 1.2 18.9 26.8 95.1 52.0 1.8 53.8 3.3 2.7 11.9 1.8 8.4 0.7 0.7 1.1 112.4 1.2 110.2 92.0 83.8 86.1 0.8 123.0 140.2 124.6 4.0 18.9 3.2 12.1 89.2 110.4 8.4 7.9 13.7 22.4 15.2 33.9 23.0 17.4 18.4 11.2 14.4 11.8 46.9 109.0 20.0 0.7 167.3 12.4 64.5 51.7 16.5 41.2 13.0 125.0 65.1 12.8 40.8 25.8 210.6 18.3 152.2 6.0 13.7 85.4 39.4 110.5 18.0 81.8 23.8 85.9 2.2 56.9 10.8 54.7 23.4 45.2 15.8 2.3 23.6 1.2 33.2 8.4 16.4 9.3 30.5 10.0 23.1 144.5 10.5 14.3 23.2 14.0 6.7 13.1 163.7 9.5 0.7 298.9 8.7 26.7 26.3 95.3 0.7 21.7 67.8 45.4 177.5 36.3 435.6 0.7 6.6 9.1 10.7 9.3 205.3 8.8 6.3 56.8 LDHA ENSG00000134333 "Lactate dehydrogenase A" P00338 11 18394560-18408425 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 2198.1;Basal respiratory cells: 2133.0;Extravillous trophoblasts: 2086.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015336, CAB069404" Uncertain Supported Vesicles,Cytosol NA NA 170000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol Vesicles "CAB015336: AB_2134947, CAB069404: " "unprognostic (8.83e-2)" "prognostic unfavorable (2.78e-5)" "unprognostic (3.81e-2)" "unprognostic (1.73e-1)" "unprognostic (3.43e-3)" "unprognostic (4.66e-3)" "prognostic unfavorable (3.26e-8)" "prognostic unfavorable (2.27e-6)" "unprognostic (1.08e-1)" "unprognostic (1.88e-2)" "prognostic unfavorable (8.09e-6)" "unprognostic (1.76e-2)" "prognostic unfavorable (9.69e-9)" "unprognostic (4.15e-2)" "unprognostic (1.89e-1)" "unprognostic (3.07e-1)" "unprognostic (1.05e-2)" 444.5 358.1 64.3 139.5 68.4 184.6 330.4 54.0 72.1 203.1 58.4 278.5 158.1 151.1 43.8 450.6 189.2 75.5 361.2 68.4 73.7 440.2 729.2 242.0 97.2 73.6 74.9 149.7 171.5 26.6 95.9 113.9 94.9 170.1 117.4 443.8 267.5 81.8 947.5 468.6 296.6 124.2 58.5 185.3 181.1 95.2 67.4 115.3 180.8 500.3 146.5 266.2 314.4 65.9 1261.4 730.9 28.4 415.2 599.8 399.3 400.6 1186.1 1148.5 936.9 1366.4 324.5 196.6 909.3 380.3 1110.8 727.1 979.2 716.1 1715.1 2082.2 331.3 422.6 329.6 629.4 588.5 148.9 811.2 235.8 411.1 760.3 380.3 373.7 1670.8 550.8 292.3 462.8 431.7 1127.7 319.4 674.8 509.3 182.7 413.2 849.4 432.0 298.0 768.0 1546.6 284.5 220.5 279.3 642.7 518.6 230.8 431.4 241.7 192.9 546.9 1228.3 455.3 1094.7 14.3 348.0 545.1 899.4 1767.1 415.0 434.1 98.4 147.1 79.7 93.8 165.0 105.2 70.4 122.1 99.6 202.1 54.4 78.1 81.0 47.1 91.3 169.3 68.0 140.8 237.6 64.3 68.4 54.0 72.1 68.4 73.7 73.6 74.9 94.9 58.5 67.4 65.9 421.7 73.7 201.6 21.5 220.8 2198.1 475.6 2133.0 523.0 464.2 213.6 229.5 241.8 175.8 837.3 309.0 146.0 509.8 427.2 696.1 434.3 1293.9 204.4 180.0 317.4 492.8 45.6 123.2 38.7 1532.3 2086.2 544.4 163.6 485.8 262.9 205.3 205.6 514.4 659.3 514.8 33.5 285.1 649.0 224.4 1155.1 129.6 287.7 373.9 1177.5 20.6 973.4 444.2 170.0 9.5 12.6 1771.4 590.3 205.0 376.0 546.8 1765.0 682.5 178.1 481.4 190.7 251.6 706.3 195.5 44.0 422.9 1723.2 501.7 410.9 196.2 362.1 530.8 LDLRAD4 C18orf1 ENSG00000168675 "Low density lipoprotein receptor class A domain containing 4" O15165 18 13217498-13652755 "Predicted intracellular proteins, Predicted membrane proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.2;lymphoid tissue: 49.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 338.9;Inhibitory neurons: 308.5;Late spermatids: 231.5;Microglial cells: 429.1;Oligodendrocyte precursor cells: 318.7;Oligodendrocytes: 284.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 35.3;JURKAT: 37.4;MOLT-4: 131.3;REH: 31.6;U-698: 26.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047633, HPA065246" Approved Supported Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA047633: , HPA065246: AB_2685444" "unprognostic (2.52e-1)" "unprognostic (4.31e-3)" "unprognostic (5.30e-2)" "unprognostic (1.23e-1)" "unprognostic (1.64e-1)" "unprognostic (3.94e-3)" "unprognostic (9.73e-2)" "unprognostic (2.26e-2)" "unprognostic (2.21e-2)" "unprognostic (2.92e-2)" "unprognostic (2.30e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (4.58e-4)" "unprognostic (2.51e-2)" "unprognostic (4.38e-2)" "unprognostic (6.58e-2)" "unprognostic (8.18e-2)" 6.5 4.3 13.9 7.3 38.0 9.7 6.3 34.6 25.9 7.8 37.4 5.8 6.1 12.4 0.9 3.9 11.3 4.6 16.6 10.7 16.4 4.0 10.3 4.6 6.5 46.1 33.2 2.3 3.3 2.9 6.9 6.2 38.6 8.6 2.1 7.0 3.0 5.3 15.4 4.2 7.2 5.7 27.3 5.6 5.0 9.2 48.2 49.3 4.4 9.5 3.8 5.3 5.3 39.6 0.2 0.3 1.4 0.8 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.1 0.1 0.1 2.7 1.6 0.8 0.4 0.0 0.0 0.0 17.1 1.7 35.3 7.0 1.2 0.0 1.7 0.9 0.0 0.0 0.0 0.0 0.0 0.4 37.4 0.4 0.7 0.0 2.6 131.3 1.1 2.9 0.3 8.9 31.6 0.1 1.2 0.0 1.1 2.4 3.9 0.5 2.2 0.0 1.9 3.8 4.7 2.4 1.3 11.5 0.2 1.9 5.6 0.4 26.1 0.0 6.9 6.4 12.8 7.0 2.1 6.5 7.7 5.7 5.2 5.8 5.6 3.9 4.4 8.2 7.6 12.1 9.1 8.5 5.9 3.4 4.5 13.9 38.0 34.6 25.9 10.7 16.4 46.1 33.2 38.6 27.3 48.2 39.6 19.4 3.2 4.7 143.3 79.2 10.5 2.7 0.8 0.0 5.4 26.0 16.9 18.4 0.0 5.0 1.8 70.9 0.6 21.0 6.8 1.9 5.1 135.2 16.3 22.0 16.6 58.7 7.6 338.9 3.6 0.7 16.5 13.3 7.8 23.5 7.6 25.0 24.4 21.1 0.0 308.5 9.1 2.0 27.4 160.5 231.5 11.1 56.2 14.2 429.1 13.6 4.7 3.1 318.7 284.9 0.7 2.6 24.5 11.7 13.5 15.6 2.3 13.7 18.7 6.6 2.3 9.7 5.4 4.9 0.4 7.7 1.6 66.0 0.2 8.8 3.2 LECT2 "chm-II, chm2" ENSG00000145826 "Leukocyte cell derived chemotaxin 2" O14960 5 135922279-135954983 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "liver: 477.9" "Group enriched" "Detected in some" 15 "Early spermatids: 147.7;Hepatocytes: 100.7;Late spermatids: 55.8" "Cancer enriched" "Detected in single" 216 "liver cancer: 35.1" "Region enhanced" "Detected in some" "cerebellum: 6.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA043883, HPA058246" Enhanced Supported Vesicles,Cytosol "Secreted to blood" NA NA 26500000 5300000 "Cluster 17: Basophils - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 20: HeLa - Mitochondria" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol Vesicles "HPA043883: AB_2678714, HPA058246: " "prognostic favorable (4.16e-5)" "unprognostic (2.57e-2)" "unprognostic (3.52e-1)" 0.2 0.5 0.4 0.4 0.8 2.4 0.4 6.3 2.8 0.1 0.0 0.2 0.5 0.3 0.8 0.4 0.1 0.4 0.1 0.9 0.0 0.6 477.9 0.3 0.9 0.0 0.0 0.3 0.1 0.2 0.0 0.2 0.1 0.4 0.2 3.1 0.7 0.2 2.1 1.4 0.9 0.1 0.0 0.9 0.3 8.8 0.0 0.2 0.4 0.0 0.2 0.1 0.0 1.1 0.3 0.4 0.5 0.7 0.2 0.4 0.6 0.1 0.0 0.0 0.0 0.1 0.4 0.8 0.6 0.3 0.3 0.5 0.0 0.2 0.0 0.3 1.0 0.7 0.7 1.3 0.3 1.0 0.1 0.2 0.1 0.3 0.3 0.6 0.1 0.8 0.2 0.3 0.6 0.0 0.4 0.4 0.5 0.3 0.6 0.5 0.5 0.2 0.2 0.9 0.3 0.6 0.0 0.2 0.0 0.9 0.1 0.5 0.8 0.3 0.4 0.4 0.1 1.1 0.5 0.3 0.3 0.9 0.8 0.6 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.4 0.8 6.3 2.8 0.9 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 147.7 0.0 0.1 0.3 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 100.7 0.0 0.0 0.1 0.0 0.0 2.9 0.0 55.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 6.6 0.0 0.0 1.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.1 LGMN "LGMN1, PRSC1" ENSG00000100600 Legumain Q99538 14 92703807-92748679 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 1448.9;Macrophages: 346.1;Syncytiotrophoblasts: 416.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "plasmacytoid DC: 209.2" "Lineage enriched" "Detected in all" 12 "dendritic cells: 209.2" "Cell line enhanced" "Detected in many" "RPMI-8226: 898.6;U-266/70: 462.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001426 Enhanced Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 2000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoplasm "HPA001426: AB_1079247" "unprognostic (1.19e-1)" "unprognostic (1.16e-1)" "unprognostic (2.37e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (3.29e-2)" "unprognostic (4.52e-2)" "unprognostic (1.31e-1)" "unprognostic (5.03e-2)" "unprognostic (3.50e-2)" "unprognostic (4.70e-2)" "unprognostic (2.47e-1)" "prognostic favorable (4.70e-4)" "unprognostic (8.06e-2)" "unprognostic (3.64e-2)" "unprognostic (7.18e-3)" "unprognostic (7.24e-2)" 173.7 44.4 37.6 82.2 38.6 20.6 69.7 31.7 60.8 52.6 51.2 102.5 110.4 30.8 36.8 64.5 36.6 145.8 85.3 40.0 40.3 205.9 111.1 107.3 177.0 35.6 37.3 33.0 37.9 247.0 24.9 262.1 42.4 51.9 105.9 19.7 56.4 32.2 50.4 32.7 97.6 65.0 35.9 202.2 107.0 29.8 62.8 52.8 93.2 50.4 54.9 144.7 52.1 49.4 33.2 47.5 30.8 57.4 94.3 76.0 108.4 70.3 67.0 71.7 84.2 36.9 58.6 18.2 101.5 116.5 44.3 81.5 0.0 60.8 33.7 1.6 36.2 1.2 24.4 42.8 27.7 1.0 2.7 54.2 29.1 68.4 39.4 21.3 82.1 33.7 7.4 150.9 5.2 45.2 8.9 1.2 15.1 208.2 32.1 8.4 27.1 898.6 59.2 129.1 33.6 23.2 97.9 59.4 53.0 66.8 43.9 0.6 47.2 35.3 44.8 64.5 21.8 462.5 58.0 25.0 20.0 0.2 69.1 1.9 1.6 0.1 0.8 3.1 1.6 17.0 5.1 1.3 19.3 14.5 15.2 9.0 1.6 3.7 1.0 209.2 9.7 7.0 37.6 38.6 31.7 60.8 40.0 40.3 35.6 37.3 42.4 35.9 62.8 49.4 34.9 57.7 128.0 8.8 33.9 23.1 37.5 36.0 22.2 10.6 31.2 37.6 29.8 42.9 48.1 31.3 93.8 181.8 24.5 64.2 9.8 61.3 1.3 79.4 23.5 38.3 36.5 22.7 19.2 50.6 140.2 63.8 73.4 177.7 8.8 17.6 276.3 46.4 1448.9 13.5 41.0 31.1 95.6 317.6 89.0 3.3 30.4 346.1 48.0 27.2 37.5 23.6 2.1 10.6 15.2 50.5 57.1 57.9 24.7 44.6 163.4 220.4 20.9 19.8 19.7 40.4 62.1 19.9 17.6 22.3 17.5 416.3 8.2 15.1 48.3 44.7 LGSN "GLULD1, LGS" ENSG00000146166 "Lengsin, lens protein with glutamine synthetase domain" Q5TDP6 6 63275951-63319983 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 2.0;liver: 3.8;placenta: 1.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 3.5;Inhibitory neurons: 3.7;Late spermatids: 4.4;Oligodendrocytes: 5.9;Proximal tubular cells: 5.6;Respiratory ciliated cells: 3.0" "Cancer enriched" "Detected in some" 4 "lung cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 6.2;BEWO: 3.3;CACO-2: 1.6;HeLa: 1.8;Karpas-707: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA030957, HPA039983" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Vesicles" "HPA030957: AB_10670149, HPA039983: AB_2676784" "unprognostic (1.94e-1)" "unprognostic (1.72e-1)" "unprognostic (1.12e-1)" "unprognostic (9.03e-2)" "unprognostic (2.81e-1)" "unprognostic (1.01e-1)" "unprognostic (5.05e-4)" "unprognostic (1.26e-1)" "unprognostic (1.74e-1)" "unprognostic (1.08e-1)" "unprognostic (2.13e-1)" "unprognostic (2.53e-2)" "unprognostic (4.51e-3)" "unprognostic (1.64e-3)" "unprognostic (1.31e-1)" "unprognostic (2.19e-1)" 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.4 0.2 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 2.0 3.8 0.2 0.0 0.3 0.1 0.0 0.3 0.0 0.0 1.1 0.2 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.2 0.0 0.0 0.0 0.0 3.3 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.4 0.2 0.1 0.1 0.3 0.1 0.2 0.1 0.1 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.0 0.0 0.0 2.2 0.0 1.1 1.9 0.1 1.2 2.0 0.0 0.1 0.0 0.0 3.5 0.2 0.5 0.1 0.0 0.0 0.0 0.3 0.0 1.1 0.3 0.0 3.7 0.7 0.0 0.3 0.0 4.4 0.3 0.1 0.0 1.9 0.0 0.0 0.0 1.5 5.9 0.0 0.3 0.0 0.1 0.2 0.1 5.6 3.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 1.4 0.1 0.1 0.8 0.2 LHFPL2 KIAA0206 ENSG00000145685 "LHFPL tetraspan subfamily member 2" Q6ZUX7 5 78485215-78770021 "Predicted membrane proteins" Fertilization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 121.9;Microglial cells: 209.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.9;plasmacytoid DC: 6.3" "Group enriched" "Detected in many" 9 "dendritic cells: 6.3;granulocytes: 7.9;monocytes: 3.9" "Cell line enhanced" "Detected in many" "GAMG: 116.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042402, HPA076743" Uncertain Approved "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "Nuclear bodies, Vesicles" "HPA042402: AB_10794276, HPA076743: " "unprognostic (2.19e-2)" "unprognostic (3.86e-2)" "unprognostic (2.00e-2)" "unprognostic (1.09e-1)" "unprognostic (2.40e-1)" "unprognostic (4.45e-2)" "prognostic unfavorable (2.73e-4)" "unprognostic (3.44e-3)" "unprognostic (2.32e-1)" "unprognostic (8.43e-2)" "unprognostic (3.62e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (3.45e-7)" "unprognostic (3.40e-2)" "unprognostic (3.88e-2)" "unprognostic (1.34e-2)" "unprognostic (7.85e-2)" 18.2 18.8 10.9 19.6 11.5 18.4 20.5 12.0 13.4 14.0 15.3 17.7 23.8 18.0 18.9 6.3 9.1 22.6 12.2 10.1 11.1 3.1 6.4 19.7 15.2 17.2 13.7 18.5 11.4 10.4 5.7 14.8 14.9 11.4 17.5 5.5 19.3 24.7 2.7 5.7 21.2 22.0 14.6 4.3 14.8 9.1 18.5 14.8 9.1 4.1 14.4 36.3 10.3 18.7 9.8 36.1 10.6 14.1 63.0 18.0 32.7 11.0 28.0 18.7 32.5 12.8 28.4 24.4 4.8 21.7 116.4 16.6 10.2 11.8 30.6 0.2 9.1 24.3 7.2 21.6 46.5 0.1 0.2 20.7 46.6 57.3 88.4 29.6 44.8 0.9 0.2 17.8 42.9 5.2 0.1 1.4 11.8 7.9 10.3 4.7 15.0 6.8 7.1 42.6 2.0 14.4 17.9 6.6 62.5 22.3 3.9 3.0 29.8 21.7 11.8 60.1 33.2 0.7 0.1 34.1 57.5 0.2 39.7 7.9 3.9 4.0 0.0 1.4 0.1 0.6 0.0 0.0 0.9 0.6 0.0 0.0 0.7 0.0 0.5 6.3 0.1 1.3 10.9 11.5 12.0 13.4 10.1 11.1 17.2 13.7 14.9 14.6 18.5 18.7 13.5 3.2 3.4 20.2 5.7 8.7 7.3 5.2 0.6 6.6 18.2 15.6 3.7 1.5 7.6 7.3 0.0 4.0 20.3 34.8 0.0 9.1 1.5 7.5 26.3 21.4 2.4 10.7 15.8 12.9 2.6 38.1 10.7 14.6 0.0 121.9 35.3 1.4 60.1 3.3 7.9 16.3 6.1 40.4 14.7 1.7 19.3 36.3 10.6 209.9 5.5 5.4 0.0 55.3 4.6 17.0 16.1 33.4 3.3 10.4 29.8 0.7 3.9 2.2 6.6 19.1 13.1 0.7 1.7 1.4 4.8 7.3 1.3 22.1 10.0 12.4 LHFPL3 LHFPL4 ENSG00000187416 "LHFPL tetraspan subfamily member 3" Q86UP9 7 104328700-104907232 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 30.5;retina: 23.6" "Cell type enriched" "Detected in some" 19 "Oligodendrocyte precursor cells: 4790.3" "Cancer enriched" "Detected in some" 12 "glioma: 27.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 1.6;SH-SY5Y: 2.1;SK-BR-3: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069691 Approved Vesicles No NA "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Vesicles "HPA069691: AB_2686171" "unprognostic (1.20e-2)" "unprognostic (6.91e-2)" "unprognostic (4.59e-3)" "unprognostic (5.03e-2)" "unprognostic (2.27e-2)" "unprognostic (2.22e-1)" "unprognostic (1.07e-1)" "unprognostic (6.96e-2)" "unprognostic (5.81e-2)" "unprognostic (5.99e-3)" "unprognostic (8.50e-3)" "unprognostic (3.07e-1)" "unprognostic (1.33e-1)" 0.0 0.1 20.2 0.1 10.8 0.0 0.0 13.1 7.4 3.3 0.0 0.7 1.4 0.6 0.0 0.0 0.3 0.0 0.0 5.4 15.5 1.4 0.0 1.5 0.0 7.3 14.2 0.1 0.9 0.0 0.0 0.0 7.5 0.2 0.1 23.6 0.0 0.0 0.0 0.2 1.2 0.0 10.2 0.4 0.3 0.1 30.5 0.0 0.0 0.0 0.1 0.0 0.2 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.1 0.0 1.9 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.2 10.8 13.1 7.4 5.4 15.5 7.3 14.2 7.5 10.2 30.5 9.5 0.0 0.0 0.5 3.6 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.2 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.3 0.2 7.7 0.1 0.0 0.0 31.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 245.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.8 0.0 1.3 0.0 4790.3 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 7.3 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 LHFPL5 "DFNB67, dJ510O8.8, MGC33835, Tmhs" ENSG00000197753 "LHFPL tetraspan subfamily member 5" Q8TAF8 6 35797206-35845397 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.8;epididymis: 12.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 13.5;Excitatory neurons: 8.0;Glandular and luminal cells: 2.8;Inhibitory neurons: 3.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 3.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029421, HPA055110" Uncertain Approved Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Vesicles "HPA029421: , HPA055110: AB_2682697" "unprognostic (2.35e-1)" "unprognostic (6.45e-2)" "unprognostic (2.41e-2)" "unprognostic (1.22e-3)" "unprognostic (1.96e-1)" "unprognostic (1.78e-1)" "unprognostic (4.89e-3)" "unprognostic (2.96e-3)" "unprognostic (2.46e-2)" "unprognostic (1.47e-8)" "unprognostic (5.53e-2)" "unprognostic (1.70e-1)" "unprognostic (2.15e-1)" "unprognostic (1.41e-1)" 0.9 1.1 4.1 2.7 4.6 18.8 0.8 4.8 5.6 0.3 0.3 0.9 3.0 1.5 12.4 1.3 0.6 1.7 0.7 3.6 2.6 0.6 0.8 1.0 2.8 0.0 0.3 1.1 5.6 0.3 0.5 1.3 0.2 1.0 0.7 8.2 2.4 0.4 1.4 7.6 2.5 0.3 0.0 2.2 1.7 1.5 1.9 0.5 1.4 0.2 0.6 0.6 0.0 2.7 2.3 1.5 3.0 3.1 0.2 0.6 4.6 1.6 0.3 0.1 0.4 2.7 2.0 3.6 1.2 0.6 1.9 2.9 0.2 0.8 0.3 1.6 2.6 3.2 5.3 4.0 0.0 3.4 2.2 0.5 0.3 0.3 0.4 2.1 0.2 3.6 3.1 5.1 0.9 1.9 2.5 6.2 2.6 0.7 1.5 2.2 1.1 2.0 0.7 5.6 3.4 1.9 1.6 2.3 1.0 2.9 2.4 1.9 2.6 3.1 1.7 2.5 2.4 3.2 3.0 3.1 1.1 3.6 1.6 2.9 0.6 0.5 0.3 0.3 0.3 0.5 0.3 0.3 0.1 0.9 0.4 0.5 3.3 0.6 0.4 0.7 0.4 0.1 4.1 4.6 4.8 5.6 3.6 2.6 0.0 0.3 0.2 0.0 1.9 2.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 1.3 0.7 0.3 0.0 0.4 8.0 0.2 0.0 0.2 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.0 3.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 LIG1 ENSG00000105486 "DNA ligase 1" P18858 19 48115445-48170603 "Enzymes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, DNA replication" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 34.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037015, HPA041431, HPA048071" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" Yes No "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Golgi apparatus, Vesicles" "CAB037015: , HPA041431: AB_2677476, HPA048071: AB_2680248" "unprognostic (1.83e-1)" "unprognostic (1.48e-3)" "unprognostic (6.45e-2)" "unprognostic (9.76e-2)" "unprognostic (9.47e-2)" "unprognostic (9.24e-3)" "unprognostic (1.17e-3)" "unprognostic (2.28e-1)" "unprognostic (6.03e-3)" "unprognostic (4.26e-1)" "unprognostic (1.78e-2)" "unprognostic (1.10e-3)" "prognostic unfavorable (5.75e-5)" "unprognostic (3.59e-2)" "unprognostic (4.09e-2)" "unprognostic (1.59e-2)" "unprognostic (1.55e-2)" 2.8 3.2 3.3 9.0 3.2 34.5 3.6 3.6 3.5 5.5 2.3 6.8 8.6 4.0 2.5 7.4 5.9 2.3 1.6 2.9 3.2 2.9 4.0 3.4 15.6 4.4 2.9 6.0 7.0 4.2 4.8 5.1 4.5 4.0 4.2 2.7 4.8 3.0 3.8 10.4 9.6 2.2 2.6 6.0 5.2 8.2 3.1 20.7 5.1 1.0 9.7 3.5 5.0 3.9 43.4 64.1 57.1 37.6 2.6 4.2 41.7 27.0 19.1 44.1 47.2 35.0 42.9 83.7 15.3 11.2 11.9 30.1 24.7 26.7 16.9 45.2 48.8 56.4 38.7 47.5 1.0 63.0 43.7 5.7 2.5 23.0 3.4 5.0 24.0 51.0 46.3 29.8 23.3 44.0 107.3 123.7 33.6 46.7 15.9 84.1 48.4 43.6 12.3 64.8 36.3 36.5 32.3 33.6 10.1 12.5 22.7 44.5 22.6 31.7 54.3 23.9 40.3 29.3 49.0 83.1 12.7 38.0 33.3 0.0 1.6 2.6 7.8 6.8 7.7 10.9 8.8 8.3 1.6 10.0 11.5 8.2 1.3 12.1 3.3 1.5 10.9 5.7 3.3 3.2 3.6 3.5 2.9 3.2 4.4 2.9 4.5 2.6 3.1 3.9 3.9 3.2 13.6 5.9 16.1 8.3 9.5 8.7 24.5 21.5 7.8 12.3 3.9 7.2 10.3 3.7 10.4 31.1 9.6 10.2 7.9 5.8 19.3 12.0 5.1 8.3 0.0 36.2 4.2 5.2 35.8 6.8 5.1 8.3 6.3 23.1 5.0 5.3 16.4 8.4 5.6 10.0 6.1 3.5 6.8 8.5 2.1 6.6 3.6 3.7 7.2 10.9 11.3 3.5 8.4 3.0 4.4 1.9 23.0 2.8 7.6 4.7 19.5 11.3 13.1 4.5 6.5 13.5 26.1 15.9 9.1 10.0 13.9 6.0 15.3 8.7 LINGO4 LRRN6D ENSG00000213171 "Leucine rich repeat and Ig domain containing 4" Q6UY18 1 151800264-151805419 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "skeletal muscle: 21.3;tongue: 5.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Melanocytes: 1.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "cerebellum: 1.8;hypothalamus: 1.0;midbrain: 2.7;pons and medulla: 4.0;thalamus: 1.4" "Region enriched" "Detected in many" 7 "spinal cord: 19.7" HPA060781 Uncertain Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 15: Hepatocytes - Hemostasis" "Golgi apparatus, Vesicles" "HPA060781: AB_2684361" "unprognostic (2.71e-2)" "unprognostic (1.98e-1)" "unprognostic (1.33e-3)" "unprognostic (1.96e-1)" "unprognostic (8.65e-2)" "unprognostic (3.16e-2)" "unprognostic (1.49e-5)" "unprognostic (1.14e-1)" "unprognostic (2.04e-1)" "unprognostic (2.39e-1)" "unprognostic (1.94e-4)" "unprognostic (6.92e-2)" "unprognostic (3.94e-4)" "unprognostic (3.84e-1)" "unprognostic (1.65e-1)" "unprognostic (7.06e-2)" "unprognostic (5.60e-2)" 0.0 2.0 0.1 0.1 0.1 0.0 0.1 4.1 0.2 0.1 0.1 0.1 0.1 0.0 0.8 0.1 0.7 0.1 0.7 0.3 0.5 0.3 1.1 0.2 0.2 2.8 1.6 0.0 0.4 0.5 1.4 0.0 3.9 0.7 0.1 0.1 0.6 0.2 21.3 0.6 0.2 0.0 1.3 0.1 0.4 0.6 1.6 1.2 0.6 5.6 0.2 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 4.1 0.2 0.3 0.5 2.8 1.6 3.9 1.3 1.6 2.1 0.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.3 0.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 LIPA "CESD, LAL" ENSG00000107798 "Lipase A, lysosomal acid type" P38571 10 89213569-89414557 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 398.4" "Cell type enhanced" "Detected in many" "Hofbauer cells: 515.0;Kupffer cells: 714.8;Macrophages: 303.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 167.3;intermediate monocyte: 355.1;myeloid DC: 123.6;non-classical monocyte: 198.5" "Group enriched" "Detected in all" 6 "dendritic cells: 123.6;monocytes: 355.1" "Cell line enhanced" "Detected in many" "A-431: 354.4;AN3-CA: 367.8;ASC TERT1: 450.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034892, HPA057052" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" "Intracellular and membrane" NA NA 280000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "CAB034892: AB_784329, HPA057052: AB_2683322" "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (1.17e-1)" "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (7.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (4.28e-2)" "unprognostic (1.08e-1)" "unprognostic (7.30e-3)" "unprognostic (1.39e-2)" "unprognostic (1.40e-1)" "unprognostic (4.42e-2)" "unprognostic (3.42e-2)" "unprognostic (5.71e-2)" 76.0 46.3 43.5 66.7 65.2 39.8 47.8 64.1 74.4 54.0 39.0 67.7 167.6 38.8 21.7 28.6 37.8 83.5 24.2 43.5 53.1 44.9 218.9 169.5 159.3 74.7 55.5 32.7 21.4 68.9 12.7 79.1 82.2 30.7 72.0 12.6 22.5 33.8 11.8 18.7 227.5 47.7 65.4 398.4 34.3 13.4 57.0 44.5 31.6 22.5 45.5 58.4 19.3 115.5 354.4 49.4 30.7 367.8 343.5 450.8 10.0 171.4 194.8 65.5 121.5 18.6 176.6 63.9 34.0 264.4 73.7 338.7 13.8 92.8 53.6 86.1 34.7 25.1 19.1 81.5 87.6 48.8 48.9 190.4 69.2 72.9 40.6 88.2 14.9 45.4 0.3 108.5 58.3 28.2 45.7 34.6 22.7 62.4 60.0 26.4 39.0 60.5 69.2 50.9 10.5 21.8 41.4 49.9 133.9 20.4 64.4 65.8 26.2 58.8 15.5 132.1 44.6 60.0 65.7 25.8 71.4 112.9 82.1 4.2 167.3 16.9 40.0 355.1 40.6 31.9 35.8 38.8 123.6 33.4 36.7 40.4 7.1 29.8 198.5 25.0 38.2 159.6 43.5 65.2 64.1 74.4 43.5 53.1 74.7 55.5 82.2 65.4 57.0 115.5 75.5 41.7 33.8 11.1 35.9 17.7 30.3 58.1 25.6 5.4 16.1 14.1 9.6 45.8 31.9 33.1 0.0 34.8 31.4 2.8 21.5 35.1 6.8 11.4 20.4 56.7 21.8 27.4 34.4 36.2 32.9 34.6 21.4 15.5 28.5 10.8 54.7 66.7 515.0 16.8 15.1 8.9 40.7 714.8 69.0 2.7 11.5 303.1 48.0 30.0 71.7 33.1 29.9 15.1 143.0 19.3 12.0 21.8 15.4 11.3 161.0 14.0 28.8 2.2 6.6 19.7 21.0 5.1 13.8 31.9 12.5 20.0 33.1 17.6 9.1 24.0 LITAF "FLJ38636, PIG7, SIMPLE, TP53I7" ENSG00000189067 "Lipopolysaccharide induced TNF factor" Q99732 16 11547722-11636381 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" DNA-binding "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 701.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 2578.1" "Lineage enriched" "Detected in all" 6 "granulocytes: 2578.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006960 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Golgi apparatus, Vesicles" "HPA006960: AB_1079254" "unprognostic (2.26e-1)" "unprognostic (4.96e-2)" "unprognostic (2.32e-3)" "unprognostic (1.03e-1)" "prognostic unfavorable (2.02e-4)" "unprognostic (4.07e-2)" "unprognostic (8.75e-3)" "unprognostic (3.60e-1)" "unprognostic (6.15e-3)" "unprognostic (1.04e-1)" "unprognostic (4.61e-2)" "unprognostic (5.01e-1)" "unprognostic (1.85e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (6.25e-4)" "unprognostic (3.57e-2)" "unprognostic (1.60e-1)" 139.3 43.7 53.5 165.8 81.9 207.0 95.5 79.6 70.0 121.2 70.5 121.1 46.3 100.5 77.8 62.7 108.2 114.1 63.9 52.2 63.0 182.3 107.7 192.1 112.3 94.0 79.4 67.6 64.6 56.5 39.0 71.3 92.7 105.9 116.1 63.9 116.4 83.4 36.3 71.6 57.9 93.5 77.3 119.6 70.7 10.6 77.6 68.6 116.8 37.6 123.7 214.1 83.1 109.4 79.2 157.8 89.4 43.8 13.9 11.0 90.7 100.2 309.0 93.6 139.1 62.6 206.3 39.9 126.8 86.1 108.7 95.5 40.1 186.4 88.4 304.2 45.8 2.8 117.1 310.3 212.9 12.5 12.9 35.0 320.8 79.6 210.7 84.4 0.3 2.7 25.3 149.5 1.5 75.8 1.8 183.3 146.4 104.0 0.6 12.1 19.6 228.2 79.0 110.4 22.2 68.0 172.9 219.4 183.9 136.3 122.5 66.7 0.8 38.7 65.3 23.0 24.2 59.2 140.6 100.5 45.1 95.8 225.5 508.8 149.5 284.0 459.6 130.2 277.2 174.0 284.0 412.7 178.0 173.9 318.9 381.4 2578.1 274.5 81.9 220.1 350.3 584.9 53.5 81.9 79.6 70.0 52.2 63.0 94.0 79.4 92.7 77.3 77.6 109.4 297.5 44.8 70.0 7.5 176.7 157.4 336.2 365.4 68.3 2.2 180.5 157.6 48.8 148.7 222.2 163.7 0.0 56.4 505.5 305.4 485.2 245.8 2.3 112.2 151.9 76.3 17.5 18.3 1.1 72.9 471.9 156.7 39.8 108.1 214.9 1.1 94.2 52.9 227.8 0.0 1.6 153.1 175.0 156.9 701.0 11.3 56.2 422.0 156.5 7.5 391.8 232.7 433.5 11.6 59.5 123.3 236.1 68.4 186.3 239.8 23.3 104.3 150.3 5.4 52.6 89.6 176.1 0.2 5.4 37.1 132.1 37.1 278.7 16.6 88.9 368.6 LIX1 "C5orf11, Lft" ENSG00000145721 "Limb and CNS expressed 1" Q8N485 5 97091867-97142753 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 32.4;retina: 42.6" "Cell type enriched" "Detected in some" 13 "Muller glia cells: 289.4" "Cancer enhanced" "Detected in many" "glioma: 13.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.2" "Lineage enriched" "Detected in single" 6 "B-cells: 2.2" "Group enriched" "Detected in some" 13 "RPTEC TERT1: 53.5;SuSa: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA058426 Uncertain Approved "Vesicles,Cytokinetic bridge,Cytosol" Yes NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 5: Muller glia cells - Visual perception" Cytosol "Vesicles, Cytokinetic bridge" "HPA058426: AB_2683715" "unprognostic (3.18e-1)" "unprognostic (4.53e-2)" "unprognostic (9.46e-2)" "prognostic unfavorable (2.48e-4)" "unprognostic (8.96e-2)" "unprognostic (6.60e-2)" "unprognostic (1.34e-1)" "unprognostic (4.70e-1)" "unprognostic (7.63e-2)" "unprognostic (1.58e-2)" "unprognostic (3.52e-1)" "unprognostic (2.01e-1)" "unprognostic (4.88e-2)" "unprognostic (2.16e-1)" "unprognostic (1.26e-1)" "unprognostic (9.61e-2)" 0.0 0.3 24.0 0.2 22.3 0.3 0.0 24.7 16.2 0.0 7.1 0.6 0.1 0.1 0.1 0.1 0.1 0.1 0.1 26.6 30.7 3.1 0.0 0.0 0.5 31.1 32.4 0.0 0.0 0.0 1.5 0.4 24.7 1.5 0.3 42.6 0.0 5.8 0.0 0.1 0.2 0.2 32.2 0.1 0.4 0.1 26.1 0.0 4.6 0.0 0.0 0.0 0.0 29.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 53.5 0.0 0.1 0.0 0.0 0.0 0.0 31.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 24.0 22.3 24.7 16.2 26.6 30.7 31.1 32.4 24.7 32.2 26.1 29.1 0.0 0.0 0.0 21.2 1.3 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.7 0.0 0.1 12.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.0 0.0 1.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 3.3 1.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 289.4 0.0 0.5 1.4 0.0 0.0 0.0 0.1 0.1 0.0 2.3 0.0 9.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LLGL2 "HGL, Hugl-2" ENSG00000073350 "LLGL scribble cell polarity complex component 2" Q6P1M3 17 75525080-75575209 "Predicted intracellular proteins" "Cell cycle, Cell division, Exocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 297.5;Pancreatic endocrine cells: 249.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.1" "Group enriched" "Detected in many" 6 "dendritic cells: 1.1;NK-cells: 2.1;T-cells: 3.1" "Cell line enhanced" "Detected in many" "CACO-2: 92.6;CAPAN-2: 134.2;MCF7: 132.1;OE19: 101.6;RT4: 92.9;SK-BR-3: 127.5;T-47d: 96.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA022913 Uncertain Supported Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Vesicles "HPA022913: AB_1852930" "unprognostic (1.18e-1)" "unprognostic (4.18e-2)" "unprognostic (2.89e-2)" "unprognostic (1.34e-1)" "unprognostic (3.43e-1)" "prognostic favorable (9.25e-4)" "unprognostic (2.60e-2)" "unprognostic (2.40e-1)" "unprognostic (7.97e-2)" "unprognostic (3.49e-1)" "prognostic favorable (6.00e-5)" "unprognostic (6.22e-3)" "prognostic favorable (6.14e-9)" "unprognostic (1.14e-2)" "unprognostic (2.77e-2)" "unprognostic (4.15e-3)" "unprognostic (1.56e-2)" 3.9 7.8 2.7 14.2 6.0 4.6 9.0 6.2 3.6 16.3 9.5 64.5 54.5 4.1 24.0 55.5 14.9 21.3 3.4 2.1 4.1 56.7 26.9 27.6 5.1 6.0 5.9 4.9 74.5 17.3 11.2 6.3 6.2 14.7 28.4 10.4 43.4 12.5 1.3 34.1 55.4 1.9 4.0 24.5 64.2 6.9 4.5 2.3 17.8 0.9 5.7 9.6 25.9 9.8 60.1 54.7 0.3 10.4 0.0 0.0 22.7 0.4 0.6 1.1 0.6 92.6 134.2 4.0 13.6 0.2 5.0 73.7 10.1 10.1 0.2 5.1 18.1 4.0 16.1 35.1 0.6 0.6 8.5 0.0 13.6 0.2 2.1 1.3 2.0 5.8 7.9 5.4 0.0 132.1 3.5 7.1 7.4 101.6 21.2 6.9 0.2 14.9 28.4 92.9 22.1 4.5 11.8 127.5 4.0 12.2 96.6 9.4 0.5 0.2 0.6 0.2 1.0 6.4 9.3 1.8 0.4 0.3 2.7 0.0 0.1 0.1 3.1 0.3 0.7 0.3 0.7 2.1 0.1 0.3 0.1 1.2 0.1 2.1 0.1 1.1 0.5 0.4 2.7 6.0 6.2 3.6 2.1 4.1 6.0 5.9 6.2 4.0 4.5 9.8 7.7 89.8 51.6 3.6 9.0 10.6 34.7 17.3 12.0 15.5 28.8 20.1 3.8 74.4 40.5 90.1 166.8 3.7 44.7 297.5 31.3 84.1 0.6 88.7 7.2 9.0 95.1 0.8 1.1 138.9 8.5 3.5 158.5 87.7 22.2 7.2 4.6 25.0 6.0 8.4 0.8 113.0 32.6 3.8 6.0 1.0 4.7 4.7 3.6 5.6 5.5 28.1 50.4 0.5 49.9 249.4 159.8 4.1 16.1 37.6 84.5 47.0 53.9 117.5 6.6 1.3 6.4 1.5 18.9 27.5 21.7 4.4 21.8 7.5 136.1 89.7 LMAN1 "ERGIC-53, ERGIC53, F5F8D, FMFD1, gp58, MCFD1, MR60" ENSG00000074695 "Lectin, mannose binding 1" P49257 18 59327823-59359265 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 502.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002320, CAB037163" Supported Supported "Endoplasmic reticulum,Vesicles" NA NA 18000000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "Endoplasmic reticulum" "CAB037163: AB_532237, HPA002320: AB_1079256" "unprognostic (5.64e-2)" "unprognostic (8.96e-3)" "unprognostic (4.20e-3)" "unprognostic (1.61e-1)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (1.65e-1)" "unprognostic (5.40e-3)" "unprognostic (1.16e-1)" "unprognostic (2.03e-1)" "unprognostic (2.40e-2)" "unprognostic (1.06e-1)" "unprognostic (5.79e-2)" "unprognostic (4.28e-2)" "unprognostic (5.37e-3)" "unprognostic (7.05e-2)" "unprognostic (3.71e-3)" 36.0 43.3 14.8 39.4 16.4 21.7 43.8 16.9 19.4 66.0 20.1 34.1 45.7 46.1 52.9 31.1 48.8 31.9 42.6 13.8 19.4 64.5 181.1 33.6 28.4 17.1 16.0 43.3 53.1 74.3 32.7 54.8 17.4 58.4 39.3 40.0 69.0 43.7 33.3 20.3 49.1 37.7 16.2 27.4 59.3 21.2 16.0 32.1 86.5 41.1 34.8 40.1 21.2 20.4 90.6 52.7 55.1 46.4 125.6 215.6 110.7 159.6 227.9 105.7 140.5 52.7 85.2 16.0 110.7 191.0 75.7 108.1 79.0 90.5 191.0 61.7 50.4 52.5 65.4 109.5 148.9 183.6 77.0 144.7 106.8 102.5 208.1 198.1 108.1 54.3 89.7 173.6 104.2 24.5 53.5 37.9 37.8 45.8 64.5 60.0 100.1 176.0 58.9 67.6 37.5 40.9 80.6 78.0 91.6 76.8 57.8 70.8 89.8 170.5 59.9 55.2 94.0 131.6 71.3 76.2 179.1 96.0 142.6 6.0 2.5 0.7 7.3 3.7 10.0 7.1 7.9 7.7 3.5 5.1 7.5 7.7 0.3 10.0 2.1 8.8 9.6 4.0 14.8 16.4 16.9 19.4 13.8 19.4 17.1 16.0 17.4 16.2 16.0 20.4 120.0 102.5 97.1 15.0 104.0 69.8 120.3 213.5 84.8 39.2 104.5 97.2 134.6 71.4 171.2 80.9 106.3 149.3 86.7 32.8 21.5 130.6 28.1 117.5 203.7 97.7 51.6 49.6 17.2 84.6 304.8 162.4 106.0 200.7 33.6 96.9 75.0 394.0 80.2 58.9 22.1 181.4 107.8 41.9 40.1 10.3 110.6 52.5 67.6 22.5 53.5 76.8 54.6 20.1 33.5 71.6 45.5 85.4 502.1 214.1 95.5 75.6 164.7 66.7 65.7 95.4 142.3 47.2 65.1 80.7 57.0 231.2 69.5 149.6 89.7 129.5 LMBRD1 "bA810I22.1, C6orf209, cblF, FLJ11240" ENSG00000168216 "LMBR1 domain containing 1" Q9NUN5 6 69672757-69867236 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Endocytosis, Gastrulation, Host-virus interaction, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 21.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016491, HPA019547" Uncertain Supported Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 25: RPMI-8226 - Immune response" "Cluster 59: Non-specific - Transcription" Vesicles "HPA016491: , HPA019547: AB_2281256" "unprognostic (1.44e-1)" "unprognostic (3.84e-2)" "unprognostic (7.67e-2)" "unprognostic (7.64e-2)" "unprognostic (2.41e-1)" "unprognostic (5.37e-2)" "unprognostic (2.26e-1)" "unprognostic (4.39e-2)" "unprognostic (2.19e-1)" "unprognostic (1.97e-1)" "unprognostic (2.22e-1)" "unprognostic (1.47e-1)" "prognostic favorable (1.07e-7)" "unprognostic (7.99e-2)" "unprognostic (1.67e-1)" "unprognostic (2.60e-2)" "unprognostic (2.68e-2)" 33.3 49.4 10.3 11.5 10.8 4.2 31.4 20.7 17.0 28.9 13.3 26.4 13.5 22.5 27.7 25.7 26.3 16.0 27.7 11.1 11.5 53.0 42.9 27.9 12.1 13.6 11.9 34.5 36.5 31.7 26.5 17.2 12.3 19.1 20.5 10.7 33.2 20.0 28.8 28.1 28.6 12.7 11.4 21.8 29.6 10.4 10.2 9.1 35.1 13.1 16.8 30.1 29.4 16.1 3.8 3.8 6.0 10.2 16.5 23.7 17.9 2.2 7.1 2.6 5.6 4.8 8.2 6.5 9.2 8.8 5.8 7.5 3.8 9.8 2.4 16.3 11.9 6.2 4.9 7.8 13.7 3.4 8.7 7.6 9.6 0.8 5.7 19.1 7.4 5.5 9.4 6.1 6.0 8.1 2.5 4.7 4.6 8.5 4.8 0.3 15.4 37.8 17.0 13.8 5.5 8.5 0.9 7.0 13.3 3.0 4.6 25.3 1.1 3.9 4.6 4.3 2.8 8.8 5.5 2.8 2.3 4.0 12.3 6.5 2.2 3.9 2.0 2.5 2.5 12.1 2.9 1.9 1.7 21.0 3.1 2.3 11.4 2.6 4.8 2.2 3.7 2.1 10.3 10.8 20.7 17.0 11.1 11.5 13.6 11.9 12.3 11.4 10.2 16.1 49.7 64.1 38.3 82.3 93.4 29.1 41.9 45.2 71.2 73.7 39.2 25.4 40.6 50.1 56.0 58.8 110.5 69.6 36.2 79.0 19.6 49.0 28.8 48.3 22.7 41.1 18.7 18.5 119.2 49.6 59.2 56.1 36.7 61.7 40.5 15.7 44.6 60.5 42.1 55.5 144.6 37.6 44.7 66.9 36.3 9.3 35.4 52.0 32.0 79.6 49.3 56.3 28.8 122.2 156.6 42.0 51.0 33.8 82.7 19.6 78.7 64.1 65.5 90.8 26.3 36.4 33.9 22.5 16.9 43.4 38.1 77.4 43.2 26.9 31.7 34.2 LMX1A "LMX1, LMX1.1" ENSG00000162761 "LIM homeobox transcription factor 1 alpha" Q8TE12 1 165201867-165356715 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "choroid plexus: 20.4" "Group enriched" "Detected in some" 16 "Early spermatids: 30.6;Enteroendocrine cells: 41.9;Late spermatids: 23.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "HPA028051, HPA030088" Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA028051: AB_10599731, HPA030088: AB_10601106" "unprognostic (1.73e-1)" "unprognostic (9.57e-2)" "unprognostic (7.58e-2)" "unprognostic (1.59e-1)" "unprognostic (2.17e-1)" "unprognostic (2.82e-1)" "unprognostic (2.63e-1)" "unprognostic (3.22e-2)" "unprognostic (2.10e-3)" "unprognostic (1.51e-1)" "unprognostic (9.82e-3)" 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.1 0.3 20.4 0.3 1.0 0.0 0.0 0.1 0.1 0.0 0.1 0.7 1.3 0.0 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.0 3.1 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.4 0.1 0.6 0.0 0.0 0.0 0.0 1.3 2.5 0.0 0.1 1.0 0.0 0.2 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.7 1.3 0.2 2.1 0.5 0.0 2.5 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 30.6 0.2 0.0 0.1 41.9 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.0 0.0 0.0 23.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 LNP1 NP3 ENSG00000206535 "Leukemia NUP98 fusion partner 1" A1A4G5 3 100401532-100456319 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "retina: 46.1;testis: 29.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 50.1;Early spermatids: 147.6;Horizontal cells: 257.4;Spermatocytes: 91.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.4" "Lineage enriched" "Detected in single" 4 "T-cells: 1.4" "Cell line enhanced" "Detected in many" "PC-3: 18.7;U-266/84: 17.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "amygdala: 6.8;cerebral cortex: 8.7;hippocampal formation: 7.3;olfactory bulb: 5.0" HPA047926 Approved "Nuclear speckles,Vesicles,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 16: U-266 - Nucleosome" "Cluster 62: Horizontal cells - Visual perception" Vesicles "Nuclear speckles, Cytosol" "HPA047926: " "unprognostic (1.78e-1)" "unprognostic (3.70e-2)" "unprognostic (8.33e-3)" "unprognostic (4.40e-3)" "unprognostic (6.33e-3)" "unprognostic (1.17e-1)" "unprognostic (1.34e-1)" "unprognostic (1.66e-3)" "unprognostic (1.81e-1)" "unprognostic (1.75e-2)" "unprognostic (1.58e-2)" "unprognostic (1.74e-2)" "unprognostic (8.28e-3)" "unprognostic (1.43e-1)" "unprognostic (7.98e-2)" "unprognostic (2.11e-1)" "unprognostic (6.08e-2)" 2.2 1.9 5.1 0.8 5.9 0.1 1.9 5.3 6.1 2.6 3.0 2.5 0.6 3.1 6.7 1.3 3.0 2.0 8.5 5.2 6.0 4.3 7.7 3.1 0.9 5.2 5.1 3.9 3.3 1.7 6.1 2.7 6.4 1.9 1.5 46.1 2.0 2.3 2.9 0.7 1.2 2.7 4.6 1.2 1.5 29.0 4.7 1.3 3.6 2.1 1.1 3.1 1.7 5.3 3.2 1.7 9.9 0.9 4.1 2.9 0.7 2.0 6.3 2.7 2.8 0.9 0.9 2.4 0.9 1.9 2.8 2.1 1.8 3.2 2.9 2.6 2.1 7.1 0.5 4.0 1.8 5.4 0.8 3.5 0.8 1.2 5.0 2.5 0.3 1.0 2.7 11.6 2.1 2.7 6.2 4.3 7.6 2.1 18.7 4.6 5.4 6.1 1.9 0.4 9.5 4.9 1.6 2.7 4.5 2.3 0.6 0.6 0.7 1.0 10.4 1.0 2.2 14.9 17.3 9.5 3.3 3.3 2.1 0.0 0.0 0.0 0.4 0.0 0.9 0.3 0.3 0.2 0.2 0.1 0.4 0.4 0.0 0.1 0.0 0.0 1.4 0.1 5.1 5.9 5.3 6.1 5.2 6.0 5.2 5.1 6.4 4.6 4.7 5.3 0.9 0.0 0.5 4.2 1.8 1.0 1.3 0.7 2.2 42.2 2.2 1.9 10.5 0.0 1.5 1.8 50.1 1.5 0.3 0.6 7.9 0.8 147.6 0.9 2.3 1.2 2.4 6.1 6.9 1.0 1.9 3.2 3.1 0.7 0.0 1.2 0.0 1.7 0.6 257.4 11.3 1.6 0.0 0.3 0.3 34.2 3.4 0.3 21.4 0.0 0.7 17.1 1.0 7.5 3.7 0.6 0.5 1.2 7.5 0.8 1.1 6.0 3.3 44.3 0.0 1.9 4.6 91.8 3.3 0.6 0.6 0.4 0.7 0.7 0.8 0.5 LNX2 "MGC46315, PDZRN1" ENSG00000139517 "Ligand of numb-protein X 2" Q8N448 13 27545913-27620529 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040698 Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "Plasma membrane, Cytosol" "HPA040698: AB_10673138" "unprognostic (4.97e-2)" "unprognostic (1.97e-2)" "unprognostic (3.29e-2)" "unprognostic (1.47e-1)" "unprognostic (1.15e-1)" "unprognostic (2.65e-2)" "unprognostic (1.12e-1)" "unprognostic (8.38e-2)" "unprognostic (1.16e-1)" "unprognostic (9.27e-3)" "unprognostic (4.21e-2)" "unprognostic (8.79e-2)" "prognostic favorable (7.09e-13)" "unprognostic (4.18e-3)" "unprognostic (1.67e-1)" "unprognostic (2.21e-1)" "unprognostic (2.84e-2)" 3.2 6.7 2.0 3.7 2.3 3.8 6.9 5.1 3.0 4.0 6.5 10.7 14.2 3.0 4.8 10.6 4.6 7.9 8.7 2.4 2.8 7.9 20.5 11.5 4.0 1.7 1.8 4.3 19.6 7.1 3.2 3.7 1.7 6.4 10.5 8.0 9.4 4.8 5.9 6.6 13.4 3.8 1.9 3.1 9.9 12.3 2.4 7.8 9.9 5.9 5.1 6.2 6.7 1.9 6.4 3.5 6.5 7.2 6.7 3.1 6.8 5.6 4.9 5.4 4.9 12.7 12.5 9.6 4.7 4.9 9.8 12.0 11.8 15.0 7.0 6.0 4.9 12.3 7.2 9.3 10.5 6.6 7.6 2.6 22.8 3.8 14.7 15.4 9.9 9.9 3.8 3.6 7.9 7.9 10.0 4.4 7.2 29.0 3.9 9.2 12.7 5.0 11.9 11.1 16.7 3.5 7.6 15.4 10.1 8.0 10.7 5.2 12.6 3.1 4.3 3.1 4.6 3.5 6.3 9.9 2.0 6.3 4.4 2.0 0.3 0.9 0.5 0.1 0.7 0.5 0.6 0.7 0.3 0.5 0.6 0.6 0.3 1.1 0.2 0.1 1.0 0.2 2.0 2.3 5.1 3.0 2.4 2.8 1.7 1.8 1.7 1.9 2.4 1.9 4.5 32.1 27.6 9.8 5.6 25.4 27.7 15.8 23.9 8.9 13.3 7.6 11.4 25.8 11.4 20.2 2.1 1.5 5.5 27.8 3.9 10.2 16.4 11.0 2.7 7.2 10.2 18.9 23.2 14.2 8.1 3.2 11.7 14.7 1.3 10.8 9.3 59.2 2.3 5.0 8.0 17.0 8.2 5.0 7.7 7.3 2.8 2.8 10.6 21.5 2.3 4.4 5.2 3.0 6.7 11.0 23.5 3.4 5.4 16.8 17.8 7.8 15.9 16.3 0.0 3.1 3.5 15.6 17.5 14.8 22.0 3.0 5.5 11.1 11.9 20.9 LOXL4 "FLJ21889, LOXC" ENSG00000138131 "Lysyl oxidase like 4" Q96JB6 10 98247690-98268194 "Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Basal respiratory cells: 141.0" "Cancer enhanced" "Detected in all" "melanoma: 44.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "BJ hTERT+: 249.7;CAPAN-2: 301.6" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033876, HPA037609" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "CAB033876: AB_2135101, HPA037609: AB_2675579" "unprognostic (9.91e-3)" "unprognostic (3.97e-2)" "unprognostic (1.81e-2)" "unprognostic (1.43e-2)" "prognostic unfavorable (6.49e-4)" "unprognostic (7.71e-2)" "unprognostic (1.75e-2)" "unprognostic (8.38e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (9.57e-4)" "unprognostic (2.51e-1)" "unprognostic (4.97e-2)" "unprognostic (5.25e-2)" "unprognostic (5.77e-3)" "unprognostic (1.28e-1)" "unprognostic (6.10e-2)" "unprognostic (7.40e-3)" 8.2 2.4 0.7 1.6 0.9 0.5 11.9 1.1 0.7 11.8 2.3 10.4 1.9 7.0 3.0 2.0 7.8 1.8 3.0 0.8 1.2 6.6 6.0 4.4 0.4 1.3 1.3 7.1 6.6 1.2 1.9 5.8 1.3 6.6 1.8 2.6 19.6 10.8 8.3 4.0 3.2 7.6 1.0 2.7 2.9 5.5 1.0 1.4 7.0 1.5 0.7 5.0 7.4 1.0 0.0 1.6 0.1 0.3 6.9 29.5 0.9 32.1 249.7 2.6 26.6 5.4 301.6 0.1 28.4 25.1 1.1 0.3 0.1 0.0 2.2 0.0 0.2 0.0 4.4 13.3 6.7 0.0 0.0 3.3 0.0 4.4 0.0 0.4 0.1 0.0 0.3 0.0 0.4 0.0 0.0 2.3 0.6 0.1 0.5 0.1 2.9 0.0 0.0 0.0 0.1 1.0 0.1 0.0 0.0 8.7 0.2 0.7 0.7 0.2 53.7 3.2 1.1 0.0 0.0 0.2 0.5 0.0 35.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.7 0.9 1.1 0.7 0.8 1.2 1.3 1.3 1.3 1.0 1.0 1.0 0.3 6.4 1.5 0.7 0.3 0.9 2.1 141.0 0.0 0.4 6.5 6.5 1.6 4.3 17.5 31.3 0.0 0.2 1.7 0.1 0.0 11.1 0.3 1.5 1.2 0.9 0.0 0.0 0.1 0.5 0.4 6.0 0.0 4.2 1.3 1.1 2.2 0.4 0.2 0.0 0.1 0.2 8.2 0.0 2.1 0.4 4.1 0.2 0.0 9.4 0.0 5.4 0.0 0.0 0.0 3.0 0.0 1.5 0.3 7.9 0.0 0.4 6.3 0.1 0.0 5.2 2.2 0.1 0.2 0.1 0.9 0.4 0.2 0.7 0.0 3.4 LPAR4 "GPR23, LPA4, P2RY9, P2Y5-LIKE, P2Y9" ENSG00000147145 "Lysophosphatidic acid receptor 4" Q99677 X 78747709-78757094 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.8;ovary: 3.6" "Cell type enhanced" "Detected in some" "Astrocytes: 10.1;Fibroblasts: 4.2;Leydig cells: 20.2;Oligodendrocyte precursor cells: 3.5;Skeletal myocytes: 3.6" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "basophil: 6.3" "Lineage enriched" "Detected in single" 19 "granulocytes: 6.3" "Cell line enhanced" "Detected in some" "AF22: 9.3;NTERA-2: 15.2;RH-30: 6.4;U-937: 3.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA046563, HPA054951, HPA055571" Uncertain Supported "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear bodies, Vesicles" "HPA046563: AB_2732529, HPA054951: AB_2682646, HPA055571: AB_2682853" "unprognostic (1.62e-1)" "unprognostic (3.53e-1)" "unprognostic (1.58e-1)" "unprognostic (5.81e-4)" "unprognostic (3.12e-2)" "unprognostic (4.85e-3)" "unprognostic (2.81e-1)" "unprognostic (2.57e-1)" "unprognostic (6.75e-2)" "unprognostic (6.73e-2)" "unprognostic (8.91e-2)" "unprognostic (4.86e-4)" "unprognostic (2.99e-5)" "unprognostic (9.27e-3)" "unprognostic (1.00e-1)" "unprognostic (3.58e-2)" "unprognostic (6.03e-3)" 0.5 0.0 1.8 0.4 1.3 0.3 0.8 1.1 1.7 0.6 1.1 0.3 0.0 1.1 0.3 0.6 0.3 0.8 0.7 3.0 1.2 0.1 0.1 0.1 0.0 1.8 1.7 3.6 0.4 0.0 0.1 0.0 1.3 0.2 0.4 0.1 0.3 0.1 0.0 0.5 0.3 0.5 2.6 0.1 0.4 0.3 1.1 0.7 0.1 0.3 0.4 0.3 0.2 3.8 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.6 1.0 1.2 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.6 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.1 2.1 0.0 0.4 1.7 15.2 0.0 0.2 0.8 6.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 3.4 0.0 2.6 0.0 0.0 0.2 0.0 0.6 1.2 0.0 0.7 0.7 3.7 1.5 6.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.8 1.3 1.1 1.7 3.0 1.2 1.8 1.7 1.3 2.6 1.1 3.8 1.2 0.0 0.0 10.1 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.1 0.8 0.0 0.0 0.1 0.0 0.0 4.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.4 0.5 20.2 0.1 1.8 1.0 0.6 1.0 0.0 3.5 0.1 0.0 0.0 2.6 0.1 0.2 0.0 0.1 0.0 0.0 0.0 3.6 0.4 0.0 0.3 1.5 0.4 0.0 0.4 0.2 0.0 0.2 LPL LIPD ENSG00000175445 "Lipoprotein lipase" P06858 8 19901717-19967259 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant, FDA approved drug targets, Hyperlipidemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 937.4;heart muscle: 407.8" "Cell type enhanced" "Detected in many" "Adipocytes: 453.0;Cardiomyocytes: 489.0;Granulosa cells: 495.2;Horizontal cells: 206.9;Sertoli cells: 236.7" "Cancer enhanced" "Detected in all" "glioma: 39.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.2" "Lineage enriched" "Detected in single" 6 "monocytes: 4.2" "Cell line enriched" "Detected in some" 5 "AF22: 391.6" "Region enhanced" "Detected in many" "basal ganglia: 45.3" "Group enriched" "Detected in all" 5 "basal ganglia: 79.2;spinal cord: 59.3" HPA048749 Supported Vesicles "Secreted to blood" NA NA 4200000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA048749: AB_2680511" "unprognostic (5.52e-2)" "unprognostic (3.16e-1)" "unprognostic (6.41e-2)" "unprognostic (3.03e-1)" "unprognostic (4.14e-2)" "unprognostic (1.01e-2)" "unprognostic (1.88e-4)" "unprognostic (1.05e-1)" "unprognostic (6.78e-2)" "unprognostic (8.20e-2)" "unprognostic (2.54e-2)" "unprognostic (5.28e-1)" "unprognostic (1.18e-1)" "unprognostic (4.20e-3)" "unprognostic (4.16e-3)" "unprognostic (1.19e-1)" "prognostic unfavorable (6.07e-4)" 937.4 15.9 6.8 9.1 53.2 0.9 255.4 20.3 12.2 2.7 8.9 12.0 1.5 3.7 0.5 2.8 2.7 8.6 407.8 10.7 9.5 19.1 0.7 62.1 8.5 7.4 7.7 10.6 6.3 181.5 4.1 14.7 7.9 3.8 5.8 11.1 24.4 64.7 86.4 8.3 13.3 4.1 5.5 1.6 8.4 1.0 11.5 4.3 10.6 127.3 2.8 6.1 4.7 8.8 0.0 0.0 391.6 0.1 8.1 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.8 0.0 0.0 0.1 0.3 0.0 71.5 0.0 0.2 8.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.1 0.7 9.6 0.0 0.0 0.0 0.0 68.4 0.0 0.0 8.4 0.2 0.0 0.0 0.1 13.5 0.0 1.8 0.0 0.0 8.1 0.0 3.5 0.0 0.1 0.1 0.1 0.1 32.6 0.0 0.9 0.7 0.0 1.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.2 6.8 53.2 20.3 12.2 10.7 9.5 7.4 7.7 7.9 5.5 11.5 8.8 453.0 12.8 104.9 1.0 0.4 1.5 0.1 0.0 0.6 2.8 114.7 5.7 489.0 0.0 0.6 0.0 2.1 0.4 0.9 0.1 15.6 0.0 0.8 0.2 2.5 56.1 0.0 0.0 1.9 0.0 0.7 13.6 0.0 0.3 6.3 495.2 2.9 0.0 108.5 206.9 0.4 1.0 0.0 14.8 4.2 1.3 1.2 38.2 14.2 1.9 2.0 2.3 0.0 9.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 0.4 2.9 2.7 236.7 91.4 68.1 0.4 0.2 0.2 0.6 0.4 2.3 4.3 2.8 0.1 LRG1 LRG ENSG00000171236 "Leucine rich alpha-2-glycoprotein 1" P02750 19 4536402-4540036 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "liver: 944.2" "Cell type enriched" "Detected in many" 7 "Hepatocytes: 793.0" "Cancer enriched" "Detected in many" 9 "liver cancer: 160.9" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 19 "neutrophil: 285.2" "Lineage enriched" "Detected in many" 44 "granulocytes: 285.2" "Cell line enhanced" "Detected in many" "Hep G2: 15.4;SK-BR-3: 15.7;THP-1: 26.2;U-937: 48.7" "Low region specificity" "Detected in single" "HPA001888, HPA001889" Enhanced Approved Vesicles "Secreted to blood" NA NA 21000000000 42000000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 32: U-937 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "HPA001888: AB_1079276, HPA001889: AB_1079275" "unprognostic (5.54e-3)" "unprognostic (1.78e-1)" "unprognostic (1.78e-1)" "unprognostic (1.42e-1)" "unprognostic (2.64e-2)" "unprognostic (1.05e-1)" "unprognostic (1.88e-1)" "unprognostic (1.13e-1)" "unprognostic (1.01e-1)" "unprognostic (1.16e-2)" "unprognostic (1.46e-3)" "unprognostic (9.83e-2)" "prognostic unfavorable (3.66e-6)" "unprognostic (4.06e-2)" "unprognostic (1.45e-1)" "prognostic favorable (3.49e-4)" "unprognostic (2.60e-2)" 7.2 4.5 0.6 17.8 0.5 31.4 4.3 1.2 2.6 8.7 1.1 7.3 6.7 1.9 5.9 22.7 10.0 15.5 1.2 0.6 0.6 9.8 944.2 7.8 0.8 0.7 0.7 1.5 44.1 0.1 1.6 1.9 1.9 4.4 4.7 0.1 20.9 6.2 1.0 4.8 3.3 2.2 0.5 16.2 13.6 0.3 0.9 1.2 1.3 1.4 6.5 13.3 3.8 0.9 10.8 0.1 0.0 0.0 0.0 0.1 8.0 0.0 0.0 0.0 0.0 1.0 8.0 3.6 13.3 0.0 0.5 1.4 0.0 1.7 0.1 13.4 0.4 0.3 0.2 15.4 0.0 0.4 13.9 4.1 0.0 0.0 0.0 0.0 0.1 0.0 9.6 0.2 0.0 0.6 0.0 11.3 0.2 8.2 0.0 0.1 0.3 11.3 1.0 2.0 0.0 0.0 0.1 15.7 0.1 1.3 4.8 26.2 0.3 0.0 0.2 0.1 0.2 0.1 0.1 0.2 0.0 48.7 0.0 2.4 6.4 15.0 0.1 2.0 0.1 0.4 0.3 0.1 1.6 0.4 0.1 0.1 285.2 0.2 1.3 0.2 1.1 2.2 0.6 0.5 1.2 2.6 0.6 0.6 0.7 0.7 1.9 0.5 0.9 0.9 13.4 12.8 54.3 0.0 3.3 8.0 33.1 56.8 18.2 0.1 14.2 2.5 0.5 60.1 50.2 14.7 0.0 0.8 0.5 44.7 1.9 112.7 0.0 38.0 1.8 24.7 4.9 13.2 0.0 64.1 12.4 3.0 31.6 17.3 12.0 0.2 38.2 793.0 6.7 1.7 0.0 26.3 32.6 19.9 5.0 0.0 0.0 14.7 1.8 0.0 7.3 0.1 0.0 0.0 0.0 40.6 11.9 0.0 1.7 4.5 10.8 4.9 76.1 0.1 0.0 2.3 3.3 0.0 0.2 9.0 5.8 1.4 1.9 3.4 27.6 30.2 LRP1 "A2MR, APOER, APR, CD91, IGFBP-3R, IGFBP3R1, LRP, LRP1A" ENSG00000123384 "LDL receptor related protein 1" Q07954 12 57128483-57213361 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Endocytosis "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 109.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 273.4;Hepatocytes: 188.4;Leydig cells: 233.3;Peritubular cells: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "classical monocyte: 4.3;intermediate monocyte: 2.2;myeloid DC: 1.6;non-classical monocyte: 2.4" "Group enriched" "Detected in many" 21 "dendritic cells: 1.6;monocytes: 4.3" "Cell line enhanced" "Detected in many" "ASC diff: 484.8;ASC TERT1: 488.4;fHDF/TERT166: 222.2;HSkMC: 318.5;hTERT-RPE1: 248.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004182, CAB018621, HPA022903" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 180000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Nucleoplasm "CAB018621: AB_627893, HPA004182: AB_2667163, HPA022903: AB_10602426" "unprognostic (1.65e-1)" "unprognostic (1.61e-1)" "unprognostic (1.76e-1)" "unprognostic (2.71e-1)" "unprognostic (5.00e-2)" "unprognostic (4.33e-2)" "unprognostic (3.98e-1)" "unprognostic (8.68e-2)" "unprognostic (1.70e-1)" "unprognostic (3.37e-3)" "unprognostic (1.48e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.52e-5)" "unprognostic (2.81e-3)" "unprognostic (6.13e-2)" "unprognostic (2.80e-2)" "prognostic unfavorable (1.29e-5)" 109.2 14.1 21.3 29.0 36.3 8.2 40.0 30.2 19.7 32.3 8.0 24.1 23.2 36.9 6.2 19.3 30.3 31.5 35.5 16.7 21.9 5.7 35.0 34.0 4.9 46.0 31.5 71.0 10.7 7.8 10.2 39.8 27.9 13.8 11.2 9.9 20.3 20.2 13.0 20.4 18.4 28.9 27.1 13.6 15.1 7.3 48.9 5.6 17.6 23.5 2.7 25.5 29.3 27.6 7.7 14.5 30.4 24.2 484.8 488.4 91.2 85.3 109.0 27.5 26.7 26.9 12.4 0.4 10.4 222.2 6.0 33.6 5.3 8.7 9.7 0.7 1.3 0.4 17.9 56.4 66.5 0.5 14.6 318.5 3.1 61.8 7.2 248.7 1.7 1.1 0.4 1.3 87.2 1.7 0.2 0.4 34.8 11.0 8.8 3.2 171.0 1.6 1.9 2.2 1.4 16.4 19.0 0.6 13.2 42.0 2.9 1.2 1.2 96.0 35.0 53.9 5.2 1.1 0.1 0.2 167.4 0.1 18.7 0.0 4.3 0.0 0.0 2.2 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 2.4 0.0 0.0 1.6 21.3 36.3 30.2 19.7 16.7 21.9 46.0 31.5 27.9 27.1 48.9 27.6 24.6 12.8 8.4 113.6 3.2 24.0 11.9 28.7 19.9 29.2 4.9 19.3 14.8 15.7 14.7 1.8 0.0 87.5 1.1 81.7 0.0 7.4 1.9 9.7 111.4 13.0 4.2 0.8 39.3 1.8 53.0 273.4 49.5 4.2 6.3 36.9 11.0 188.4 73.8 8.4 41.6 14.1 6.1 145.3 28.6 8.4 233.3 102.9 28.4 89.9 48.8 154.7 1.0 173.4 6.6 14.7 27.2 184.3 4.4 5.5 86.0 2.1 15.1 7.3 39.5 129.7 77.0 1.6 2.4 35.4 16.1 125.9 4.2 11.4 25.0 12.3 LRP11 "bA350J20.3, MANSC3" ENSG00000120256 "LDL receptor related protein 11" Q86VZ4 6 149818757-149864359 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 61.3;Respiratory ciliated cells: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017267 Approved "Vesicles,Plasma membrane" NA NA 1500000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Vesicles "HPA017267: " "prognostic unfavorable (2.31e-8)" "unprognostic (3.85e-3)" "unprognostic (1.68e-1)" "unprognostic (1.30e-2)" "unprognostic (5.17e-2)" "unprognostic (4.25e-3)" "prognostic unfavorable (2.01e-5)" "unprognostic (5.05e-2)" "unprognostic (1.47e-1)" "unprognostic (2.49e-1)" "unprognostic (3.29e-1)" "unprognostic (2.63e-1)" "unprognostic (4.76e-2)" "unprognostic (2.47e-1)" "unprognostic (6.75e-2)" "unprognostic (1.34e-2)" "unprognostic (4.23e-2)" 14.5 18.0 25.2 5.3 25.8 1.4 11.8 18.7 31.5 17.2 13.8 13.1 11.7 11.4 16.4 28.6 22.3 11.3 10.8 26.7 23.3 20.3 10.0 13.6 2.9 23.6 24.9 16.5 19.8 42.8 17.6 12.5 25.0 25.5 12.3 13.5 20.1 13.0 5.2 20.6 9.1 12.0 19.7 4.1 16.3 8.0 26.0 2.4 22.9 4.8 5.9 18.0 20.8 25.0 26.5 22.9 17.2 15.0 37.8 67.2 3.5 27.7 52.1 18.5 22.4 7.3 52.9 0.2 36.7 43.3 79.4 69.4 19.2 47.1 13.3 43.7 19.4 13.3 74.3 30.4 22.6 13.2 0.8 42.8 93.1 23.0 46.5 52.5 28.9 11.8 26.8 11.0 22.3 45.4 0.5 1.3 10.4 52.0 19.6 14.5 25.5 6.4 33.9 53.8 22.4 15.6 86.7 46.3 17.0 8.5 38.8 26.4 21.1 22.6 4.8 48.4 21.3 0.1 8.7 6.3 40.9 12.9 13.9 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 25.2 25.8 18.7 31.5 26.7 23.3 23.6 24.9 25.0 19.7 26.0 25.0 7.3 6.4 2.8 17.6 0.5 11.3 14.3 17.9 5.7 12.2 10.2 6.0 8.8 12.8 18.3 20.2 2.1 2.1 0.5 7.7 5.9 6.5 27.0 61.3 6.4 7.4 29.4 5.5 42.5 22.7 1.8 20.5 15.3 16.5 0.0 12.4 9.3 9.5 3.6 8.4 44.3 5.0 16.2 1.9 6.2 31.7 16.4 1.7 14.2 11.2 0.1 6.0 0.0 17.6 40.1 19.7 4.2 14.7 0.6 22.2 4.0 7.0 107.7 5.5 0.0 10.0 11.7 14.7 10.4 14.9 14.3 5.6 1.8 15.7 13.2 23.6 LRP1B "LRP-DIT, LRPDIT" ENSG00000168702 "LDL receptor related protein 1B" Q9NZR2 2 140231423-142131016 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 22.5" "Cell type enhanced" "Detected in some" "Astrocytes: 2119.8;Excitatory neurons: 3755.5;Inhibitory neurons: 2917.8;Oligodendrocyte precursor cells: 5568.9;Oligodendrocytes: 1203.1" "Cancer enhanced" "Detected in some" "breast cancer: 0.8;glioma: 1.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.5;HEK 293: 1.7;U-138 MG: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069094, HPA074788" Approved Approved Vesicles NA NA 370000 "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA069094: AB_2686082, HPA074788: AB_2797273" "unprognostic (5.31e-4)" "unprognostic (3.68e-2)" "unprognostic (2.61e-1)" "unprognostic (7.36e-4)" "unprognostic (5.19e-2)" "unprognostic (1.26e-1)" "unprognostic (2.00e-2)" "unprognostic (3.49e-1)" "unprognostic (3.75e-1)" "unprognostic (7.02e-3)" "unprognostic (1.64e-3)" "unprognostic (1.05e-1)" "unprognostic (2.94e-3)" "unprognostic (4.85e-3)" "unprognostic (1.52e-1)" "unprognostic (1.66e-2)" "unprognostic (1.36e-1)" 3.1 1.4 18.6 0.0 22.5 0.0 1.6 7.2 18.7 0.3 0.0 0.3 0.0 0.0 2.2 0.0 0.3 0.1 0.3 21.5 8.7 0.4 0.2 0.1 0.0 6.8 9.4 0.6 0.1 0.1 1.9 0.0 8.2 0.9 0.0 2.6 0.6 1.0 4.4 0.4 0.1 0.0 3.3 0.0 0.4 0.3 11.5 0.2 5.6 3.5 0.0 0.1 0.9 19.8 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.1 0.1 0.2 1.7 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 18.6 22.5 7.2 18.7 21.5 8.7 6.8 9.4 8.2 3.3 11.5 19.8 1.4 0.0 0.0 2119.8 0.0 0.3 0.5 0.0 3.4 14.9 0.2 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 6.9 0.1 1.7 0.2 0.0 0.0 3755.5 0.0 0.0 9.1 0.0 0.5 0.0 0.1 0.0 0.5 0.0 0.0 2917.8 0.0 0.0 0.0 0.5 5.4 1.2 0.1 0.0 142.4 0.0 2.4 0.0 5568.9 1203.1 0.0 0.0 0.7 0.0 0.3 0.0 0.2 0.0 0.8 0.0 1.1 0.4 0.2 0.3 0.2 0.3 0.0 0.1 0.2 0.0 0.8 LRP2 "DBS, gp330" ENSG00000081479 "LDL receptor related protein 2" P98164 2 169127109-169362534 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Endocytosis, Hearing, Neurogenesis, Transport" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 70.5;kidney: 34.8;parathyroid gland: 44.7;retina: 29.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Cytotrophoblasts: 63.2;Oligodendrocytes: 300.1;Proximal tubular cells: 283.9" "Cancer enhanced" "Detected in many" "renal cancer: 29.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "AF22: 39.4;CACO-2: 64.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA005980, HPA064792" Enhanced Approved Vesicles,Mitochondria No NA 74000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 39: CACO-2 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Mitochondria" "HPA005980: AB_1079278, HPA064792: AB_2685353" "unprognostic (1.87e-1)" "unprognostic (1.04e-3)" "unprognostic (1.32e-3)" "unprognostic (3.65e-3)" "unprognostic (3.18e-2)" "unprognostic (1.60e-2)" "unprognostic (1.64e-3)" "unprognostic (2.99e-1)" "unprognostic (1.94e-1)" "unprognostic (1.39e-1)" "unprognostic (4.09e-2)" "unprognostic (4.38e-1)" "prognostic favorable (3.43e-5)" "unprognostic (1.37e-1)" "unprognostic (4.21e-1)" "unprognostic (2.44e-2)" "unprognostic (1.62e-2)" 1.5 0.0 5.5 0.0 23.4 0.1 9.6 18.9 13.5 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.2 7.5 14.6 34.8 0.3 1.2 0.0 30.5 17.5 0.0 0.0 44.7 0.1 7.5 31.9 0.0 0.0 29.3 0.9 0.0 0.1 0.1 0.0 0.0 14.5 0.0 0.0 0.2 18.7 0.0 17.3 0.0 0.0 0.0 0.0 70.5 0.0 0.0 39.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 64.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 4.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.2 0.0 0.5 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 23.4 18.9 13.5 7.5 14.6 30.5 17.5 31.9 14.5 18.7 70.5 0.2 6.4 43.7 1.0 3.0 0.3 0.2 0.0 0.0 2.8 22.9 15.1 2.1 2.8 2.5 3.7 87.6 63.2 0.2 0.0 17.6 0.0 3.1 0.1 0.1 0.5 0.0 0.0 1.8 0.0 2.2 1.8 0.0 0.1 2.5 0.0 0.0 0.8 5.1 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 2.5 0.0 1.9 0.0 33.1 0.0 1.5 300.1 0.0 0.0 0.0 0.0 0.0 0.0 283.9 2.2 19.5 0.0 0.0 0.3 0.1 0.8 0.0 0.0 23.1 1.7 0.0 0.0 0.2 LRR1 "LRR-1, MGC20689, PPIL5" ENSG00000165501 "Leucine rich repeat protein 1" Q96L50 14 49598761-49614672 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 29.1" "Cell type enhanced" "Detected in many" "Early spermatids: 129.5;Spermatocytes: 151.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA065703, HPA069364" Approved Approved "Nucleoplasm,Nuclear membrane,Vesicles" No No "Cluster 46: Basophils - DNA binding" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Nuclear membrane" Vesicles "HPA065703: AB_2685537, HPA069364: AB_2686129" "unprognostic (2.73e-2)" "unprognostic (1.21e-2)" "unprognostic (3.17e-2)" "unprognostic (2.26e-2)" "unprognostic (2.85e-2)" "unprognostic (9.34e-2)" "prognostic unfavorable (2.97e-4)" "unprognostic (7.34e-2)" "unprognostic (2.50e-2)" "unprognostic (8.30e-2)" "unprognostic (4.64e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (4.90e-7)" "unprognostic (6.86e-2)" "unprognostic (1.21e-1)" "unprognostic (1.86e-1)" "unprognostic (4.04e-2)" 5.7 5.5 1.6 9.1 1.7 22.6 5.6 1.7 2.1 3.0 1.6 12.2 9.6 3.7 2.4 6.7 3.3 3.6 3.2 1.5 1.6 3.1 6.1 4.2 14.0 1.8 1.7 2.4 4.3 2.9 1.2 4.0 1.8 3.2 10.0 3.2 4.1 3.4 4.0 4.7 10.1 6.1 1.7 7.5 4.6 29.1 1.8 23.2 3.4 4.8 13.3 5.4 3.5 1.9 66.5 39.3 34.2 38.4 15.1 10.6 38.2 35.0 30.8 72.5 68.7 38.4 49.1 60.9 25.1 22.9 23.2 41.7 42.2 29.8 64.1 56.5 31.3 27.4 29.4 24.6 8.5 64.5 34.2 6.9 11.3 33.9 19.4 9.2 35.8 49.2 29.3 45.4 49.2 55.2 87.2 60.1 22.5 31.7 53.0 54.8 56.2 41.4 25.4 27.1 36.9 21.7 33.1 35.3 25.4 12.1 49.9 49.6 13.1 50.6 83.1 24.8 44.4 23.6 35.9 69.0 23.6 47.7 42.9 22.4 14.2 25.4 10.1 22.7 13.5 16.1 13.3 14.8 15.0 12.6 10.8 12.3 8.2 11.1 16.9 17.7 15.7 10.5 1.6 1.7 1.7 2.1 1.5 1.6 1.8 1.7 1.8 1.7 1.8 1.9 6.4 3.2 6.5 2.0 12.1 15.6 5.7 12.0 4.6 3.8 6.5 5.6 3.6 5.7 9.3 3.7 2.1 12.6 9.2 11.8 1.9 16.8 129.5 3.4 5.3 8.9 4.8 48.4 0.9 22.7 34.2 7.8 6.6 2.9 14.5 9.5 6.8 6.6 21.6 1.7 1.1 11.0 12.2 10.4 19.2 41.6 7.5 11.5 10.6 2.8 16.7 8.1 13.4 1.0 2.0 14.1 3.7 3.4 31.3 11.2 8.7 7.5 4.3 5.2 6.6 5.5 8.0 151.7 14.0 8.8 14.9 7.7 10.5 7.5 14.5 7.0 LRRC15 LIB ENSG00000172061 "Leucine rich repeat containing 15" Q8TF66 3 194355249-194369743 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.9;skin 1: 7.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.9;Endothelial cells: 1.0;Fibroblasts: 2.3;Hepatic stellate cells: 1.8;Langerhans cells: 3.0;Suprabasal keratinocytes: 1.4" "Cancer enhanced" "Detected in many" "breast cancer: 25.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "fHDF/TERT166: 120.6;U-87 MG: 62.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA035503 Uncertain Approved "Vesicles,Plasma membrane" NA NA 1700000 "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Plasma membrane" "HPA035503: AB_10961253" "unprognostic (3.20e-2)" "unprognostic (1.45e-2)" "unprognostic (3.11e-1)" "unprognostic (6.30e-2)" "unprognostic (1.19e-2)" "unprognostic (2.04e-1)" "unprognostic (7.11e-2)" "unprognostic (2.95e-2)" "unprognostic (1.84e-1)" "unprognostic (3.53e-2)" "unprognostic (3.97e-2)" "unprognostic (1.88e-3)" "unprognostic (1.22e-8)" "unprognostic (5.81e-2)" "unprognostic (1.11e-1)" "unprognostic (5.62e-3)" "unprognostic (7.54e-3)" 1.1 0.1 0.0 1.3 0.0 0.0 3.7 0.0 0.0 2.9 0.0 1.7 0.5 1.9 0.0 0.5 1.1 1.6 0.2 0.0 0.0 0.0 0.1 2.0 0.8 0.0 0.1 0.2 0.1 0.1 0.0 2.2 0.0 0.1 3.0 0.0 1.0 0.0 0.1 7.3 0.4 0.6 0.0 1.3 1.5 0.0 0.1 0.2 1.3 0.2 4.9 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.7 0.1 0.1 0.4 0.0 0.0 1.0 120.6 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 22.5 3.7 3.0 0.0 0.0 0.0 0.0 62.7 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 LRRC17 "H_RG318M05.3, P37NB" ENSG00000128606 "Leucine rich repeat containing 17" Q8N6Y2 7 102913000-102945111 "Predicted secreted proteins" Osteogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 76.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 31.3;Granulosa cells: 68.6;Leydig cells: 101.9;Peritubular cells: 31.6;Sertoli cells: 65.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "eosinophil: 9.9" "Lineage enriched" "Detected in single" 94 "granulocytes: 9.9" "Cell line enriched" "Detected in many" 5 "LHCN-M2: 1237.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA073458 Approved "Vesicles,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Cytokinetic bridge" "HPA073458: " "unprognostic (1.77e-1)" "unprognostic (7.73e-2)" "unprognostic (4.79e-2)" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "unprognostic (4.46e-1)" "unprognostic (1.18e-1)" "unprognostic (9.76e-4)" "unprognostic (6.09e-3)" "unprognostic (2.26e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (4.12e-6)" "unprognostic (8.57e-3)" "unprognostic (4.48e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (6.30e-4)" 8.1 2.4 1.6 1.1 1.7 0.2 12.9 1.6 2.4 22.5 1.7 2.7 1.6 15.7 12.1 6.0 17.3 27.4 13.2 1.7 1.6 2.8 3.5 3.2 2.1 1.6 1.7 76.2 2.3 2.0 2.4 0.6 1.5 5.6 3.3 1.8 2.7 3.2 2.1 3.0 2.3 6.0 1.6 3.3 6.9 5.0 2.3 6.2 3.8 2.8 1.0 4.4 5.8 1.6 0.0 0.0 58.8 0.5 6.0 29.4 0.1 1.6 18.2 0.6 2.8 0.0 0.2 0.0 3.4 1.5 7.3 0.1 0.0 0.0 4.3 0.0 1.4 0.1 0.0 0.1 8.3 0.5 0.2 28.1 0.7 21.5 0.0 141.1 140.9 0.6 0.0 0.1 1237.5 0.0 0.1 0.4 3.1 0.1 0.1 0.1 244.0 0.2 0.2 0.1 1.3 1.3 0.1 0.0 0.1 0.1 0.0 1.7 11.8 0.2 1.5 15.2 2.3 1.1 0.4 0.0 0.3 0.0 0.3 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.7 1.6 2.4 1.7 1.6 1.6 1.7 1.5 1.6 2.3 1.6 3.6 0.0 1.1 4.6 0.2 0.9 0.2 0.9 0.0 3.7 0.7 0.8 1.1 0.0 0.5 1.8 2.1 0.3 0.3 0.0 0.0 1.7 3.5 2.7 15.3 4.4 0.0 0.0 6.9 0.4 0.2 31.3 1.1 4.6 1.3 68.6 6.1 0.5 0.4 0.0 8.7 0.1 2.0 0.0 2.7 2.9 101.9 0.5 5.4 10.3 0.6 0.6 0.0 2.5 5.3 0.2 0.3 31.6 0.0 0.3 0.1 0.3 0.1 2.2 65.7 16.1 17.8 0.6 0.5 0.4 0.6 0.0 0.9 6.6 0.2 0.2 LRRC24 LRRC14OS ENSG00000254402 "Leucine rich repeat containing 24" Q50LG9 8 144522388-144527033 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 13.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 103.2;Cone photoreceptor cells: 73.0;Horizontal cells: 30.3;Late spermatids: 69.0;Rod photoreceptor cells: 86.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 2.6;SCLC-21H: 2.7;SH-SY5Y: 7.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028171, HPA052250" Enhanced Approved Vesicles NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA028171: AB_2672504, HPA052250: AB_2681774" "unprognostic (1.75e-1)" "unprognostic (5.76e-2)" "unprognostic (2.33e-3)" "unprognostic (3.63e-2)" 2.1 3.6 6.2 0.1 6.4 0.3 2.3 4.1 7.8 5.0 0.8 3.1 0.3 4.4 0.2 3.8 5.4 0.1 1.9 5.4 9.0 3.7 3.2 2.7 0.2 10.0 8.3 6.1 3.0 1.2 13.3 0.2 6.5 11.5 0.1 1.4 1.5 0.6 1.2 1.8 2.6 0.2 4.5 2.1 2.4 3.0 5.3 0.3 3.4 0.1 0.0 2.9 3.2 4.8 0.2 0.5 0.4 0.9 0.4 0.3 1.1 0.3 0.4 0.4 0.3 0.1 1.0 0.5 2.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 1.3 0.3 0.6 0.2 0.3 0.0 0.6 0.4 0.2 0.3 0.0 0.2 0.2 0.5 0.6 0.1 0.0 2.6 0.7 1.0 0.1 0.1 0.5 1.1 0.0 0.4 0.1 0.3 2.7 7.4 0.2 0.1 0.2 0.0 2.3 0.8 0.0 0.1 0.7 0.3 0.1 0.5 0.1 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 6.4 4.1 7.8 5.4 9.0 10.0 8.3 6.5 4.5 5.3 4.8 0.7 0.0 2.3 8.5 1.0 0.9 0.5 0.0 0.0 103.2 2.3 2.8 0.0 1.5 0.7 1.8 73.0 0.6 0.5 2.1 3.9 0.2 23.7 1.5 1.5 1.1 10.7 0.8 3.8 0.2 0.4 1.4 3.1 1.6 0.0 4.8 0.7 3.1 0.5 30.3 6.5 2.7 0.0 0.8 1.7 69.0 2.8 0.8 5.4 1.0 0.2 18.6 1.0 4.5 2.2 0.3 1.9 3.0 1.2 1.8 1.9 3.6 0.1 86.2 0.0 2.9 1.9 11.2 3.5 1.7 0.4 0.4 0.6 8.4 1.9 0.9 LRRC37A KIAA0563 ENSG00000176681 "Leucine rich repeat containing 37A" A6NMS7 17 46292733-46337794 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 11.1" "Cell type enhanced" "Detected in some" "Astrocytes: 55.5;Excitatory neurons: 86.9;Inhibitory neurons: 82.8;Microglial cells: 49.6;Oligodendrocyte precursor cells: 60.8;Oligodendrocytes: 48.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 3.7;HeLa: 2.0" "HPA042121, HPA043056, HPA045090, HPA049080" Supported Approved Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA042121: AB_2677858, HPA043056: AB_2678294, HPA045090: AB_2679211, HPA049080: AB_2680624" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" "unprognostic (7.22e-2)" "unprognostic (3.75e-2)" "unprognostic (6.02e-1)" "unprognostic (2.94e-1)" "unprognostic (1.78e-1)" "unprognostic (3.06e-2)" "unprognostic (5.23e-2)" "unprognostic (5.20e-2)" "unprognostic (8.22e-2)" "unprognostic (2.05e-1)" "unprognostic (2.65e-3)" "unprognostic (3.37e-1)" "unprognostic (4.35e-1)" "unprognostic (1.70e-2)" "unprognostic (4.30e-2)" 2.0 1.7 1.0 0.7 1.0 0.5 2.1 1.2 3.1 3.1 0.9 2.3 0.0 2.1 0.0 2.0 3.2 0.1 1.5 1.0 1.1 2.2 1.7 2.2 0.5 1.0 0.9 2.3 2.2 0.3 3.7 0.2 1.1 2.8 0.2 1.6 2.3 0.2 4.7 3.7 2.4 0.1 0.8 2.6 2.0 11.1 1.3 0.4 2.5 0.4 0.3 2.5 2.6 1.1 0.1 0.1 0.7 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.1 1.7 0.1 3.7 0.1 0.1 1.2 0.1 0.0 0.0 0.0 0.2 0.5 0.2 2.0 1.3 0.3 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.2 0.1 0.1 0.2 0.4 0.0 0.1 0.3 0.5 0.0 0.0 1.3 1.3 0.8 0.0 0.8 0.2 0.4 0.1 0.3 0.0 0.0 0.2 1.7 0.6 0.6 1.0 0.1 0.1 1.5 1.2 0.2 0.6 1.1 1.0 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.2 0.2 0.1 0.0 1.0 1.0 1.2 3.1 1.0 1.1 1.0 0.9 1.1 0.8 1.3 1.1 0.7 3.2 0.5 55.5 1.0 0.1 0.4 0.0 0.6 0.5 0.2 0.0 4.3 0.0 0.2 0.0 0.0 0.1 0.9 1.4 1.9 0.1 21.0 0.3 0.7 0.4 1.2 0.0 86.9 0.4 0.0 0.6 2.0 0.4 1.3 0.4 0.4 0.1 0.3 0.0 82.8 1.1 0.0 2.2 0.8 2.8 0.0 0.6 0.0 49.6 0.1 0.2 0.0 60.8 48.1 0.2 0.8 0.4 0.4 0.1 1.9 0.2 0.9 0.9 0.0 0.7 0.6 1.3 1.1 0.4 0.1 0.1 1.4 0.1 1.1 0.1 LRRC37A2 FLJ45049 ENSG00000238083 "Leucine rich repeat containing 37 member A2" A6NM11 17 46511511-46555650 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "testis: 6.5" "Cell type enhanced" "Detected in many" "Astrocytes: 34.0;Early spermatids: 46.8;Excitatory neurons: 55.9;Inhibitory neurons: 55.5;Microglial cells: 34.7;Oligodendrocyte precursor cells: 47.7;Oligodendrocytes: 46.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.3;THP-1: 1.2" "HPA042121, HPA043056, HPA045090, HPA049080" Supported Approved Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA042121: AB_2677858, HPA043056: AB_2678294, HPA045090: AB_2679211, HPA049080: AB_2680624" "unprognostic (1.59e-2)" "unprognostic (3.75e-2)" "unprognostic (8.96e-2)" "unprognostic (6.35e-2)" "unprognostic (2.53e-1)" "unprognostic (2.97e-3)" "unprognostic (4.61e-3)" "unprognostic (1.63e-1)" "unprognostic (6.47e-2)" "unprognostic (2.01e-1)" "unprognostic (1.55e-3)" "unprognostic (8.00e-2)" "unprognostic (3.02e-7)" "unprognostic (8.40e-2)" "unprognostic (2.82e-1)" "unprognostic (1.52e-1)" "unprognostic (5.77e-2)" 0.5 0.1 0.2 0.2 0.2 0.5 0.5 0.8 0.2 0.3 0.1 0.3 0.0 0.3 0.0 0.2 0.3 0.0 0.1 0.1 0.1 0.6 0.1 0.3 0.2 0.4 0.1 0.2 0.2 0.4 0.7 0.0 0.3 0.3 0.3 0.4 0.2 0.3 0.6 0.6 0.4 0.2 0.0 0.1 0.2 6.5 0.4 0.4 0.3 0.2 0.2 0.4 0.3 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.6 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 0.4 0.0 0.1 0.1 0.0 0.1 0.0 0.4 1.2 0.2 0.7 0.6 0.0 0.2 0.4 0.3 0.1 0.0 0.3 0.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.2 0.1 0.1 0.4 0.1 0.3 0.0 0.4 0.0 2.5 22.4 14.6 34.0 3.8 1.5 4.2 1.0 2.2 7.1 2.6 2.2 2.5 1.5 5.1 0.0 12.5 1.1 8.5 2.3 0.0 2.6 46.8 8.3 5.6 3.0 1.8 0.8 55.9 0.9 0.9 3.2 1.5 5.5 11.4 5.4 1.4 0.8 1.4 13.5 55.5 2.5 0.0 1.2 1.8 11.5 3.4 3.5 0.0 34.7 1.8 2.4 3.1 47.7 46.4 1.0 2.7 1.9 3.0 2.5 1.2 0.4 11.3 8.8 13.1 4.1 2.7 7.9 3.0 1.4 2.3 0.7 6.1 1.7 1.6 2.9 LRRC37A3 "FLJ34306, KIAA0563" ENSG00000176809 "Leucine rich repeat containing 37 member A3" O60309 17 64854312-64919480 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 28.9" "Cell type enhanced" "Detected in many" "Astrocytes: 82.6;Excitatory neurons: 143.1;Inhibitory neurons: 161.3;Microglial cells: 75.9;Oligodendrocyte precursor cells: 110.1;Oligodendrocytes: 99.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA042121, HPA043056, HPA045090" Supported Approved Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA042121: AB_2677858, HPA043056: AB_2678294, HPA045090: AB_2679211" "unprognostic (2.28e-1)" "unprognostic (1.68e-1)" "unprognostic (1.39e-1)" "unprognostic (4.73e-2)" "unprognostic (2.92e-2)" "unprognostic (3.38e-1)" "unprognostic (1.84e-2)" "unprognostic (2.27e-1)" "unprognostic (3.29e-1)" "unprognostic (1.80e-2)" "unprognostic (5.31e-6)" "unprognostic (1.83e-1)" "prognostic unfavorable (3.25e-6)" "unprognostic (2.26e-1)" "unprognostic (4.89e-2)" "unprognostic (5.18e-2)" "unprognostic (7.43e-3)" 4.1 4.2 12.2 2.1 11.5 4.0 5.0 15.4 16.1 6.3 11.5 3.8 1.5 4.2 9.3 3.4 7.6 3.8 3.7 11.2 13.5 14.9 4.3 4.2 2.6 12.2 11.9 7.8 4.7 2.7 22.3 2.6 12.0 8.2 2.1 18.8 3.2 3.3 4.2 4.2 3.0 2.3 9.7 4.4 3.0 28.9 14.7 2.0 17.1 1.0 1.6 3.5 4.4 11.6 2.2 4.4 4.1 9.3 4.6 2.8 2.9 3.0 2.5 2.0 2.3 1.9 3.3 2.2 1.4 1.6 3.6 1.9 1.1 0.9 0.9 2.9 4.2 7.0 3.1 1.3 1.8 2.5 1.6 1.9 1.9 1.5 0.6 9.2 1.4 2.8 1.4 1.2 1.5 6.0 1.3 4.5 3.1 0.5 1.2 1.5 2.2 1.0 4.3 2.0 2.7 10.2 1.2 5.3 1.3 11.6 2.4 4.7 5.1 3.7 1.1 1.5 1.7 1.8 1.9 1.7 2.6 10.7 6.3 2.7 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.6 0.3 0.3 0.7 1.1 0.4 0.8 0.3 0.1 12.2 11.5 15.4 16.1 11.2 13.5 12.2 11.9 12.0 9.7 14.7 11.6 2.0 0.0 2.2 82.6 1.8 1.8 1.6 0.5 1.8 11.4 1.6 1.5 2.8 1.5 1.9 1.8 4.2 1.3 1.9 1.5 1.9 3.0 37.9 4.9 2.7 3.6 1.2 0.4 143.1 1.3 0.2 1.9 1.1 2.3 2.5 4.6 4.6 1.0 1.5 25.2 161.3 1.1 0.0 0.9 0.7 8.6 2.1 1.4 1.8 75.9 1.4 3.7 2.1 110.1 99.3 0.7 1.7 3.0 1.8 1.2 0.7 6.9 6.9 4.1 6.6 4.1 1.7 7.3 1.8 1.0 1.0 1.0 1.4 1.3 1.1 1.4 LRRC43 MGC35140 ENSG00000158113 "Leucine rich repeat containing 43" Q8N309 12 122167738-122203471 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 4.9;choroid plexus: 16.1;fallopian tube: 19.0;testis: 6.4" "Cell type enhanced" "Detected in some" "Early spermatids: 23.2;Endometrial ciliated cells: 21.8;Late spermatids: 43.5;Proximal tubular cells: 15.9;Respiratory ciliated cells: 35.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 1.1;HSkMC: 1.3;HUVEC TERT2: 2.7;SCLC-21H: 2.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA039425 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "Golgi apparatus" Vesicles "HPA039425: AB_2676501" "unprognostic (6.42e-3)" "unprognostic (1.33e-1)" "unprognostic (2.71e-1)" "unprognostic (2.83e-3)" "unprognostic (2.48e-2)" "unprognostic (6.93e-2)" "unprognostic (1.05e-1)" "unprognostic (1.56e-2)" "unprognostic (6.03e-5)" "unprognostic (1.19e-1)" "unprognostic (4.52e-3)" "unprognostic (2.61e-1)" "unprognostic (6.21e-4)" "unprognostic (1.93e-1)" "unprognostic (2.23e-1)" "unprognostic (3.39e-1)" "unprognostic (2.49e-1)" 0.5 0.3 2.1 0.0 2.7 0.5 0.3 1.5 2.2 1.1 16.1 0.3 0.5 0.7 1.8 0.1 19.0 0.9 0.7 2.3 2.7 2.1 0.1 1.6 0.0 3.5 4.9 0.3 0.6 1.9 2.2 0.1 2.8 0.7 0.1 0.6 1.1 1.2 0.1 0.3 0.1 0.2 3.7 0.3 0.2 6.4 2.9 0.0 1.6 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.1 0.0 0.1 0.3 0.1 0.0 0.7 0.2 0.2 0.2 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 1.1 0.0 0.2 1.3 0.0 0.4 0.0 0.0 2.7 0.2 0.0 0.0 0.5 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 2.1 0.4 0.0 0.0 0.1 0.0 0.3 0.7 0.2 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.4 0.0 0.9 0.2 0.2 0.0 0.2 2.1 2.7 1.5 2.2 2.3 2.7 3.5 4.9 2.8 3.7 2.9 1.4 0.0 6.4 0.0 4.6 0.1 0.0 0.1 1.0 0.0 0.4 0.3 0.3 0.5 0.0 2.7 1.8 4.2 0.1 1.7 0.2 1.9 0.1 23.2 21.8 0.4 0.1 0.0 0.8 3.5 0.0 0.0 0.1 0.0 0.7 0.0 0.1 0.0 0.2 0.1 0.0 2.8 0.0 2.0 0.0 0.3 43.5 0.6 0.3 0.0 1.0 0.0 0.9 2.1 2.0 0.7 0.0 0.0 0.4 0.1 0.1 0.0 15.9 35.2 0.1 0.0 0.1 0.5 8.2 1.2 0.0 0.0 0.1 0.5 0.0 0.1 0.1 LRRD1 IMAGE:4798971 ENSG00000240720 "Leucine rich repeats and death domain containing 1" A4D1F6 7 92141643-92179531 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 16.5" "Group enriched" "Detected in some" 90 "Early spermatids: 258.1;Late spermatids: 869.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA055670, HPA079440" Enhanced Approved Vesicles,Mitochondria NA NA "Cluster 17: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" Mitochondria Vesicles "HPA055670: , HPA079440: " "unprognostic (1.11e-1)" "unprognostic (1.49e-1)" "unprognostic (3.72e-1)" "unprognostic (4.01e-2)" "unprognostic (1.93e-1)" "unprognostic (1.12e-1)" "unprognostic (5.39e-2)" "unprognostic (1.14e-1)" "unprognostic (3.29e-1)" "unprognostic (1.27e-2)" "unprognostic (1.56e-2)" "unprognostic (1.81e-3)" "unprognostic (1.77e-1)" "unprognostic (7.67e-2)" "unprognostic (2.02e-1)" "unprognostic (3.13e-3)" 0.0 0.0 0.4 0.0 0.5 0.3 0.1 1.7 0.8 0.1 0.0 0.0 0.1 0.1 0.4 0.0 0.1 0.2 0.1 0.5 0.9 0.0 0.0 0.0 0.1 0.6 0.4 0.1 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.5 0.1 0.0 0.1 0.3 0.1 0.1 0.2 0.1 0.0 16.5 0.8 0.0 0.1 0.0 0.1 0.0 0.0 1.1 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.4 0.1 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.2 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.6 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.1 0.1 0.2 0.0 0.4 0.5 1.7 0.8 0.5 0.9 0.6 0.4 0.8 0.2 0.8 1.1 0.1 0.0 0.6 1.6 0.0 0.3 0.5 0.0 0.0 0.6 0.2 0.0 0.2 0.0 0.7 0.0 0.0 0.1 0.3 0.1 0.0 0.0 258.1 0.1 0.6 0.3 0.0 0.0 1.7 0.0 0.1 0.3 0.0 0.3 1.3 0.4 0.0 0.0 0.1 1.7 2.8 0.0 0.0 0.0 0.7 869.3 4.7 0.5 0.0 1.0 0.0 0.3 0.0 1.5 1.4 0.0 0.0 3.0 0.0 0.4 0.1 0.1 1.5 0.9 0.0 1.2 0.3 6.2 2.6 0.0 0.3 0.0 0.5 0.3 0.1 0.3 LRRK2 "DKFZp434H2111, FLJ45829, PARK8, RIPK7, ROCO2" ENSG00000188906 "Leucine rich repeat kinase 2" Q5S007 12 40196744-40369285 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Differentiation" "GTPase activation, Hydrolase, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lung: 52.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 502.2;Excitatory neurons: 92.0;monocytes: 133.1;Oligodendrocyte precursor cells: 256.9" "Cancer enhanced" "Detected in many" "renal cancer: 17.1;thyroid cancer: 22.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 8 "neutrophil: 58.2" "Lineage enriched" "Detected in many" 8 "granulocytes: 58.2" "Cell line enhanced" "Detected in some" "A549: 4.6;ASC TERT1: 5.6;BJ hTERT+: 3.2;RPTEC TERT1: 7.8;T-47d: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014293, CAB037160" Approved Supported Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" Vesicles "CAB037160: AB_1840989, HPA014293: AB_1853353" "unprognostic (2.67e-1)" "unprognostic (1.75e-1)" "unprognostic (6.45e-3)" "unprognostic (1.06e-1)" "unprognostic (3.00e-2)" "unprognostic (6.10e-3)" "unprognostic (2.71e-1)" "unprognostic (3.14e-1)" "unprognostic (2.25e-1)" "unprognostic (9.07e-2)" "unprognostic (2.76e-1)" "unprognostic (1.23e-1)" "prognostic favorable (3.02e-6)" "unprognostic (2.55e-2)" "unprognostic (3.43e-2)" "unprognostic (2.01e-3)" "unprognostic (5.21e-3)" 4.8 3.1 1.1 10.1 1.9 9.0 2.6 0.9 2.1 5.1 1.2 4.3 0.6 4.8 1.9 7.0 4.1 6.2 3.9 1.3 1.1 10.9 5.6 52.4 6.8 1.7 1.1 5.4 3.6 8.4 2.1 1.2 1.4 2.6 1.8 1.5 3.5 2.0 5.5 2.1 3.6 4.0 1.1 10.8 2.1 0.8 1.2 2.5 2.9 7.9 5.4 4.5 5.5 1.9 0.0 4.6 0.0 0.0 2.3 5.6 0.0 1.3 3.2 0.1 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.2 0.1 0.0 0.6 0.4 0.0 2.1 0.4 0.0 0.0 2.5 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.3 0.0 0.5 2.7 0.1 3.1 1.5 1.0 0.4 0.5 0.6 0.4 0.0 0.0 0.0 1.3 0.0 1.7 0.0 7.2 2.2 0.0 5.2 0.0 1.8 0.0 0.0 2.1 1.7 0.0 0.0 58.2 0.0 6.9 0.3 0.0 1.3 1.1 1.9 0.9 2.1 1.3 1.1 1.7 1.1 1.4 1.1 1.2 1.9 7.4 32.1 502.2 17.3 29.9 2.4 1.8 0.4 2.8 8.6 1.3 1.4 7.8 5.7 17.3 27.6 0.0 0.0 1.9 0.0 1.9 1.3 0.5 0.4 2.6 7.0 0.0 2.1 92.0 2.7 0.1 16.1 0.5 0.4 13.9 2.7 13.2 8.2 4.6 47.1 28.0 0.0 0.0 55.8 8.7 1.2 19.0 52.2 12.4 73.1 133.1 8.6 3.1 256.9 3.1 0.8 1.1 12.0 2.8 0.6 0.0 22.5 3.4 1.0 0.0 22.5 4.8 0.3 1.0 12.6 3.1 0.4 3.4 11.2 0.0 0.7 LRWD1 "CENP-33, DKFZp434K1815, ORCA" ENSG00000161036 "Leucine rich repeats and WD repeat domain containing 1" Q9UFC0 7 102464956-102473168 "Predicted intracellular proteins" "DNA replication" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 11 "testis: 275.2" "Group enriched" "Detected in many" 4 "Early spermatids: 1002.6;Spermatocytes: 677.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021320 Enhanced Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Vesicles" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 78: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Nucleoli rim" "Nucleoplasm, Vesicles" "HPA021320: AB_1853372" "unprognostic (1.50e-1)" "unprognostic (1.25e-1)" "unprognostic (1.31e-2)" "unprognostic (7.66e-3)" "unprognostic (1.60e-2)" "unprognostic (2.08e-3)" "unprognostic (1.72e-3)" "unprognostic (4.97e-2)" "unprognostic (3.34e-1)" "unprognostic (3.04e-2)" "prognostic favorable (8.71e-5)" "unprognostic (1.00e-1)" "prognostic unfavorable (1.25e-4)" "unprognostic (1.46e-2)" "unprognostic (4.14e-2)" "unprognostic (7.82e-2)" "unprognostic (9.20e-2)" 8.2 16.8 10.7 6.8 10.7 14.9 7.9 11.4 13.1 10.4 10.7 8.9 5.3 10.0 2.3 7.7 13.8 3.9 9.7 13.0 11.5 11.4 15.0 10.1 8.1 12.1 14.4 9.4 9.3 8.7 17.6 3.1 12.2 8.6 2.3 3.4 7.6 6.1 13.2 6.7 17.1 4.2 10.8 24.3 9.0 275.2 12.1 8.7 10.0 5.3 7.3 8.9 7.3 10.2 18.6 24.6 13.0 36.8 9.4 7.2 21.0 19.6 11.9 30.5 20.9 23.7 10.3 44.8 27.5 13.9 36.3 19.2 18.7 16.4 9.0 16.6 39.2 10.0 11.1 14.8 12.7 17.6 17.4 6.7 9.9 35.4 7.5 10.2 16.2 33.9 44.5 13.3 16.8 54.3 53.4 42.1 28.7 22.0 37.8 28.2 12.2 48.5 9.2 11.3 17.7 50.7 21.0 20.1 19.3 14.6 11.2 14.4 11.1 17.3 37.7 54.8 30.8 50.5 94.3 43.6 19.3 17.1 31.4 10.6 2.6 9.9 9.7 4.0 9.0 10.0 8.4 8.4 2.7 11.8 5.2 6.9 5.5 10.5 3.8 9.7 9.3 6.0 10.7 10.7 11.4 13.1 13.0 11.5 12.1 14.4 12.2 10.8 12.1 10.2 9.1 0.0 1.1 5.5 10.6 10.5 6.4 16.5 3.4 11.7 5.5 5.0 0.8 2.8 12.8 12.9 2.1 9.2 10.8 8.6 7.9 12.3 1002.6 54.4 7.3 6.5 7.8 13.7 4.7 10.5 12.4 7.0 10.7 13.7 0.0 14.8 5.7 7.2 8.8 5.0 5.0 9.8 18.3 3.4 4.0 172.3 19.0 5.0 5.4 2.8 7.2 7.9 10.3 4.5 2.8 12.4 11.2 15.8 20.2 3.9 8.6 15.9 65.3 11.4 0.0 5.4 13.6 677.0 38.3 4.5 9.8 6.2 9.3 22.2 7.5 3.4 LSM14B "bA11M20.3, C20orf40, FAM61B, FLJ25473, FT005, LSM13, RAP55B" ENSG00000149657 "LSM family member 14B" Q9BX40 20 62122461-62135374 "Predicted intracellular proteins" "Translation regulation" "Developmental protein, Ribonucleoprotein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 16 "Early spermatids: 215.2;Late spermatids: 560.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 2.2" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.2" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041274, HPA061189" Approved Supported Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 39: CACO-2 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA041274: AB_2677388, HPA061189: AB_2684448" "unprognostic (2.24e-1)" "unprognostic (2.35e-1)" "unprognostic (2.89e-1)" "unprognostic (1.85e-2)" "unprognostic (1.20e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (3.61e-5)" "unprognostic (4.99e-2)" "unprognostic (2.28e-1)" "unprognostic (5.43e-2)" "unprognostic (4.93e-3)" "unprognostic (4.69e-2)" "unprognostic (3.34e-3)" "unprognostic (6.61e-2)" "unprognostic (2.00e-1)" "unprognostic (4.53e-3)" "unprognostic (1.98e-1)" 19.7 23.9 29.3 21.0 30.1 26.7 19.8 39.5 34.5 27.5 21.6 27.4 23.4 31.2 14.2 31.6 25.7 14.5 37.7 32.3 24.1 19.0 24.4 19.3 23.5 24.2 26.6 37.4 30.4 21.3 24.9 14.9 25.9 22.0 14.3 31.2 23.7 17.4 71.6 34.6 22.8 17.6 23.2 21.7 23.3 51.9 27.1 28.8 20.9 45.3 17.8 26.5 27.3 27.2 44.4 41.6 65.0 62.5 29.0 30.3 55.3 46.0 34.1 93.7 40.9 123.4 30.1 46.5 51.7 31.9 67.9 62.9 31.5 39.6 46.4 19.2 22.9 112.3 57.8 74.3 40.0 48.6 65.1 26.1 70.4 39.1 36.1 36.7 24.3 53.8 61.4 32.7 33.0 58.7 81.2 72.7 40.2 70.8 61.0 104.3 128.5 36.9 25.5 51.7 88.8 77.0 83.9 73.5 61.3 37.5 91.6 60.9 31.8 132.9 90.0 69.1 47.3 40.8 52.1 56.8 58.5 31.7 43.4 0.0 0.4 2.2 0.3 0.3 0.1 0.5 0.2 0.4 0.3 0.5 0.2 0.3 0.6 0.0 0.2 0.4 0.2 0.1 29.3 30.1 39.5 34.5 32.3 24.1 24.2 26.6 25.9 23.2 27.1 27.2 8.6 9.6 6.8 9.1 7.3 9.7 3.5 4.7 5.2 15.1 8.4 7.1 22.8 7.2 7.9 1.8 8.4 6.4 15.3 13.5 1.9 5.0 215.2 13.3 14.1 8.0 13.9 9.5 6.2 5.3 6.0 7.5 8.2 10.3 5.1 14.8 5.0 11.6 8.6 8.4 6.8 12.0 6.1 13.2 6.8 560.0 13.4 8.8 3.6 7.5 8.2 17.2 7.2 5.0 8.4 7.1 8.2 15.8 4.7 9.2 9.7 6.7 12.1 20.3 0.0 9.5 6.4 11.2 23.1 7.6 10.1 5.2 6.9 13.4 12.4 3.0 LSM4 YER112W ENSG00000130520 "LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated" Q9Y4Z0 19 18306236-18323112 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 705.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040932 Uncertain Approved Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "HPA040932: AB_10795529" "unprognostic (2.71e-1)" "unprognostic (1.44e-1)" "unprognostic (1.43e-1)" "unprognostic (7.42e-3)" "unprognostic (1.98e-1)" "unprognostic (4.09e-2)" "unprognostic (1.10e-3)" "unprognostic (9.80e-2)" "unprognostic (1.57e-1)" "prognostic favorable (1.34e-4)" "unprognostic (8.31e-3)" "unprognostic (1.25e-1)" "prognostic favorable (2.22e-4)" "unprognostic (2.51e-2)" "unprognostic (7.23e-2)" "unprognostic (8.08e-2)" "unprognostic (1.34e-1)" 56.5 130.5 97.9 31.8 101.8 62.9 55.1 99.7 111.7 52.7 111.4 86.4 57.6 51.6 36.3 100.5 52.8 17.4 108.2 102.8 104.9 118.8 122.8 60.9 41.4 99.6 102.5 50.6 57.4 48.5 72.5 35.5 105.1 64.2 45.2 33.1 55.2 39.6 149.1 70.4 77.1 27.3 95.9 71.1 78.4 126.8 104.8 78.9 62.2 89.4 38.9 62.1 59.7 97.3 294.3 151.2 252.3 226.2 95.4 91.4 291.8 132.2 113.6 167.9 158.7 137.0 305.5 172.0 274.5 139.0 152.5 192.3 276.4 274.5 127.1 201.1 524.0 156.1 247.0 167.5 94.9 148.9 89.2 83.3 160.5 156.9 182.9 94.2 139.6 248.6 333.0 172.3 177.3 479.7 411.0 321.6 327.1 419.2 475.4 229.4 112.0 320.5 212.9 102.0 283.8 264.9 113.0 141.3 204.2 174.8 140.4 157.8 81.0 98.0 113.2 244.3 250.5 160.2 147.7 204.4 131.4 289.3 170.4 171.5 223.2 163.8 148.3 258.5 182.5 163.5 158.3 154.4 252.8 164.5 169.7 171.4 18.4 220.4 205.6 359.0 166.9 283.9 97.9 101.8 99.7 111.7 102.8 104.9 99.6 102.5 105.1 95.9 104.8 97.3 76.8 28.9 38.8 7.5 85.1 67.4 92.4 183.1 46.7 72.0 141.7 134.9 53.2 74.4 90.5 115.8 14.6 270.4 95.8 179.1 299.3 196.7 280.8 102.8 55.1 75.7 124.4 109.8 11.5 182.1 489.1 67.9 68.8 96.9 117.4 115.7 54.3 89.3 288.4 58.9 11.1 194.5 154.6 85.4 129.0 705.7 62.4 109.1 104.9 7.5 243.2 115.6 130.7 7.1 13.4 159.3 205.5 47.4 98.3 153.1 225.3 347.7 94.6 73.0 46.0 38.5 80.7 203.1 378.6 125.5 71.9 170.5 87.7 174.2 237.1 119.9 LSM8 YJR022W ENSG00000128534 "LSM8 homolog, U6 small nuclear RNA associated" O95777 7 118184144-118204035 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020116 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 32: Non-specific - Translation" "Nucleoplasm, Vesicles" "HPA020116: AB_1853385" "unprognostic (1.02e-2)" "unprognostic (6.58e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (9.85e-4)" "unprognostic (3.33e-2)" "unprognostic (7.34e-2)" "unprognostic (1.13e-3)" "unprognostic (1.87e-2)" "unprognostic (1.79e-2)" "unprognostic (9.90e-2)" "unprognostic (5.14e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (7.46e-6)" "unprognostic (4.82e-2)" "unprognostic (1.42e-1)" "unprognostic (7.80e-2)" "unprognostic (3.00e-3)" 26.8 19.1 6.2 22.3 8.3 44.8 25.6 16.5 7.7 20.5 6.2 22.0 15.5 19.9 16.5 24.4 18.7 9.2 19.2 6.3 7.5 23.7 18.5 21.2 28.9 7.5 7.4 19.8 24.9 8.4 16.3 10.1 7.7 20.8 14.2 16.7 22.7 7.8 21.7 21.6 26.0 8.3 6.8 30.9 21.3 17.3 7.2 18.2 22.1 7.8 27.5 20.0 20.6 10.5 37.2 21.2 53.7 43.6 11.3 19.4 25.3 36.1 26.4 19.2 21.5 16.8 35.6 70.0 78.9 13.4 51.5 28.2 23.1 16.3 18.6 35.9 27.7 49.5 63.3 48.6 29.2 63.9 59.1 20.8 19.6 24.6 25.8 17.7 19.6 55.8 45.8 71.2 26.1 13.2 142.9 155.6 43.6 28.9 26.0 40.8 32.0 53.3 20.3 27.8 28.2 41.6 29.2 83.0 89.1 36.9 17.3 72.7 17.4 36.9 27.7 56.3 51.2 69.9 52.0 101.1 29.1 66.9 61.5 65.3 46.5 45.5 61.8 66.7 59.8 68.0 67.8 75.6 51.5 58.0 64.6 67.5 15.4 43.9 65.7 93.2 74.2 39.5 6.2 8.3 16.5 7.7 6.3 7.5 7.5 7.4 7.7 6.8 7.2 10.5 108.5 25.6 58.6 15.0 130.3 0.0 93.6 0.0 82.6 41.5 71.8 92.1 43.5 74.4 35.3 62.5 47.9 133.2 141.2 76.8 90.1 101.2 54.6 76.1 92.8 79.6 86.4 83.1 19.5 172.0 193.6 69.0 66.3 76.4 101.4 87.1 88.5 75.3 139.8 42.1 22.4 99.1 0.0 148.9 0.0 19.1 97.3 102.2 0.0 36.5 184.9 52.6 158.6 23.6 39.1 144.8 109.0 76.0 95.6 108.6 83.6 106.8 36.5 42.0 85.5 65.3 66.2 135.3 117.8 106.7 0.0 120.8 121.1 76.1 100.7 121.2 LSMEM1 "C7orf53, FLJ39575" ENSG00000181016 "Leucine rich single-pass membrane protein 1" Q8N8F7 7 112480853-112491062 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 81.6" "Cell type enhanced" "Detected in many" "Early spermatids: 49.2;Glandular and luminal cells: 27.7;Late spermatids: 67.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HeLa: 8.7" "Group enriched" "Detected in many" 4 "amygdala: 1.4;basal ganglia: 1.0;cerebellum: 4.0;olfactory bulb: 3.3" "Low region specificity" "Detected in many" "HPA013753, HPA047988" Uncertain Supported Vesicles,Cytosol NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 7: Non-specific - Mitochondria" Cytosol Vesicles "HPA013753: AB_1848926, HPA047988: AB_2680229" "unprognostic (6.87e-2)" "unprognostic (5.94e-2)" "unprognostic (2.79e-2)" "unprognostic (2.77e-2)" "unprognostic (1.38e-1)" "unprognostic (3.01e-1)" "unprognostic (2.34e-1)" "unprognostic (1.36e-1)" "unprognostic (2.17e-1)" "unprognostic (6.68e-2)" "unprognostic (3.54e-2)" "unprognostic (2.80e-3)" "unprognostic (1.47e-6)" "unprognostic (1.56e-1)" "unprognostic (1.36e-1)" "unprognostic (4.25e-2)" "unprognostic (3.42e-2)" 2.2 2.1 1.2 0.2 1.7 0.3 1.5 2.1 2.5 1.7 1.1 2.0 0.5 1.0 1.0 2.0 1.6 0.1 2.9 1.2 1.7 4.0 7.2 4.3 0.1 1.2 1.1 1.7 5.5 0.0 2.3 0.2 1.1 2.5 0.3 0.8 1.7 0.3 81.6 1.4 2.2 0.1 0.8 4.2 2.7 2.9 1.3 0.1 2.2 17.0 0.0 1.8 2.2 1.5 0.0 0.1 0.1 0.6 0.5 0.5 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.3 0.0 0.0 0.2 0.2 8.7 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.1 0.1 0.2 0.2 0.0 0.1 0.9 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.7 1.3 0.0 0.2 0.4 0.1 0.0 0.2 0.5 0.3 0.1 0.2 0.0 0.0 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.7 2.1 2.5 1.2 1.7 1.2 1.1 1.1 0.8 1.3 1.5 16.8 0.0 2.8 5.9 5.1 5.5 2.7 1.3 9.6 2.1 12.8 23.4 9.9 2.8 2.2 1.8 2.1 1.3 9.5 17.5 0.0 0.8 49.2 12.7 18.4 5.3 3.0 0.0 8.5 0.9 1.1 7.2 7.7 27.7 0.0 0.5 1.1 1.0 4.0 0.0 7.6 5.7 0.0 1.2 4.8 67.8 0.9 13.6 1.8 3.7 1.8 0.6 0.0 1.5 5.0 0.8 7.1 0.4 4.2 6.1 5.2 0.5 1.4 3.2 0.0 22.3 8.1 0.5 0.5 9.5 4.7 1.9 6.3 2.2 5.4 3.6 LTK TYK1 ENSG00000062524 "Leukocyte receptor tyrosine kinase" P29376 15 41503637-41513887 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.2;lung: 15.1;salivary gland: 11.8" "Cell type enhanced" "Detected in some" "Distal enterocytes: 25.3;Gastric mucus-secreting cells: 18.8;Hepatic stellate cells: 11.4;Intestinal goblet cells: 7.9;Proximal enterocytes: 15.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "MAIT T-cell: 5.7;plasmacytoid DC: 5.0" "Group enriched" "Detected in many" 10 "dendritic cells: 5.0;T-cells: 5.7" "Cell line enhanced" "Detected in some" "HEL: 5.0;NB-4: 9.7;RH-30: 4.6;THP-1: 14.7" "Low region specificity" "Detected in many" HPA059545 Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 43: THP-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA059545: AB_2684057" "unprognostic (9.47e-4)" "unprognostic (5.52e-4)" "unprognostic (1.51e-1)" "unprognostic (2.49e-1)" "unprognostic (4.12e-1)" "unprognostic (5.65e-3)" "unprognostic (1.74e-2)" "unprognostic (7.22e-2)" "unprognostic (2.89e-2)" "unprognostic (2.81e-3)" "unprognostic (9.36e-3)" "unprognostic (5.36e-2)" "unprognostic (4.68e-2)" "unprognostic (5.78e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.90e-1)" 0.8 0.6 1.0 1.4 1.6 4.6 0.5 1.2 1.8 0.9 0.6 5.2 12.5 0.2 0.0 0.3 0.4 2.4 1.7 1.3 0.7 4.0 2.9 15.1 1.2 0.6 0.6 0.1 0.3 0.6 0.7 10.4 0.7 0.4 5.7 0.1 11.8 0.3 1.8 1.4 13.2 0.3 0.6 5.5 9.9 2.5 0.8 0.4 0.7 0.0 2.1 0.7 0.7 0.9 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.1 0.6 0.8 1.2 2.2 0.0 0.0 0.0 0.6 0.0 0.0 2.6 0.0 0.4 0.2 1.3 5.0 0.1 0.0 2.0 0.0 0.0 0.3 0.4 0.0 0.1 0.0 0.0 0.0 1.9 0.0 1.8 0.0 0.0 9.7 0.4 1.8 0.2 0.2 4.6 0.1 0.0 0.0 0.4 2.9 0.1 0.2 0.0 2.6 0.2 14.7 0.0 0.0 0.2 0.1 0.0 0.3 0.2 0.2 0.0 0.5 0.8 0.0 0.0 0.0 0.4 0.0 5.7 0.5 0.3 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.1 1.0 1.6 1.2 1.8 1.3 0.7 0.6 0.6 0.7 0.6 0.8 0.9 0.3 0.0 0.0 0.3 1.6 0.1 0.0 0.4 0.0 0.0 0.2 0.1 0.8 2.8 0.9 0.0 0.0 0.3 5.5 25.3 0.0 0.0 2.8 0.1 0.4 1.8 1.8 3.2 2.9 0.2 1.5 0.2 18.8 0.2 0.0 0.3 11.4 0.5 0.1 0.0 0.2 7.9 0.0 1.9 0.6 2.1 0.0 0.4 3.6 0.0 0.4 0.0 1.0 0.5 0.4 0.7 5.5 0.0 2.7 0.0 15.3 0.0 5.6 0.0 0.0 0.3 0.5 2.2 1.2 0.0 0.1 0.4 4.0 0.0 3.8 0.0 LURAP1 "C1orf190, FLJ25163, LRAP35a" ENSG00000171357 "Leucine rich adaptor protein 1" Q96LR2 1 46203334-46221256 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Early spermatids: 140.9;Late spermatids: 335.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 5.4;RPTEC TERT1: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030060, HPA030061" Uncertain Supported Vesicles,Cytosol NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 21: Non-specific - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 31: Spermatids - Spermatogenesis" Cytosol Vesicles "HPA030060: AB_10599997, HPA030061: AB_10601990" "unprognostic (3.88e-2)" "unprognostic (6.21e-2)" "unprognostic (3.22e-3)" "unprognostic (8.82e-2)" "unprognostic (1.91e-2)" "unprognostic (1.20e-1)" "unprognostic (1.03e-1)" "unprognostic (6.47e-2)" "unprognostic (2.44e-2)" "unprognostic (2.95e-2)" "unprognostic (4.14e-2)" "unprognostic (1.33e-1)" "prognostic favorable (8.81e-8)" "unprognostic (1.32e-2)" "unprognostic (2.80e-1)" "unprognostic (3.11e-2)" "unprognostic (2.39e-2)" 2.1 3.5 2.4 0.9 6.5 1.7 2.1 5.7 5.7 4.5 2.5 3.1 0.8 3.2 2.2 2.0 3.3 1.7 5.4 3.1 4.7 5.3 0.4 1.6 0.5 9.7 5.4 3.9 0.3 9.5 2.1 0.9 7.3 4.6 1.0 1.3 2.6 4.8 1.1 2.0 1.3 2.7 4.0 1.6 2.7 8.9 6.2 1.2 10.5 1.0 0.8 3.8 4.0 13.6 0.1 0.1 2.1 0.1 2.8 3.8 2.1 1.5 3.8 2.0 2.3 0.1 0.1 0.2 0.1 3.6 0.7 0.2 2.2 4.8 1.6 0.4 1.0 0.2 0.5 0.2 0.8 0.1 0.1 1.8 3.0 4.0 1.8 5.4 3.0 0.5 1.9 0.3 1.1 0.2 0.2 0.2 0.8 0.0 0.3 0.7 1.0 0.0 5.3 0.0 0.3 0.8 0.0 0.1 3.4 0.8 1.1 0.2 0.2 1.2 1.5 1.0 0.3 0.1 0.1 0.2 1.2 0.2 0.3 0.2 0.2 0.1 0.1 0.1 0.3 0.2 0.1 0.1 0.1 0.3 0.3 0.2 0.8 0.3 0.1 0.2 0.0 0.1 2.4 6.5 5.7 5.7 3.1 4.7 9.7 5.4 7.3 4.0 6.2 13.6 2.2 0.0 0.0 6.8 0.0 5.0 15.6 4.5 8.0 0.2 2.7 4.1 3.1 0.0 1.3 11.0 0.0 4.1 0.1 0.2 15.6 0.1 140.9 1.3 1.6 2.9 1.2 0.0 10.0 0.4 2.3 4.0 0.0 1.3 0.0 2.5 3.3 0.1 4.4 0.0 5.5 0.3 0.0 0.3 3.3 335.2 9.3 1.2 14.2 5.6 0.7 2.0 1.0 1.0 25.3 0.0 0.1 9.8 0.0 8.6 0.1 5.3 3.3 0.2 6.6 2.6 4.7 36.3 2.2 2.7 3.4 7.7 0.2 2.7 0.1 5.5 LY96 MD-2 ENSG00000154589 "Lymphocyte antigen 96" Q9Y6Y9 8 73991392-74029079 "Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 570.8;Kupffer cells: 544.6;Langerhans cells: 155.4;Macrophages: 198.5;monocytes: 136.0;Plasma cells: 172.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 627.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 627.0" "Cell line enhanced" "Detected in many" "GAMG: 75.1;Karpas-707: 184.9;RPMI-8226: 94.0;U-87 MG: 92.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053060 Approved Vesicles "Secreted to blood" NA NA 250000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA053060: AB_2682029" "unprognostic (2.96e-1)" "unprognostic (2.64e-2)" "unprognostic (2.11e-1)" "unprognostic (1.85e-1)" "unprognostic (1.64e-2)" "unprognostic (2.87e-1)" "unprognostic (2.12e-3)" "unprognostic (1.42e-1)" "unprognostic (8.29e-2)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (6.38e-11)" "unprognostic (2.87e-2)" "unprognostic (1.29e-2)" "unprognostic (1.60e-2)" "unprognostic (5.90e-2)" 28.6 12.4 12.9 42.4 13.5 17.9 24.7 13.1 22.7 12.9 13.8 15.7 12.3 10.5 5.4 9.0 11.1 35.3 9.5 13.0 14.4 13.2 22.8 22.0 47.4 16.3 14.8 22.6 3.7 2.4 8.0 44.9 14.9 6.1 14.5 1.2 11.4 6.7 3.8 4.4 9.9 20.3 14.7 59.6 10.6 4.7 13.9 16.2 7.3 9.8 39.3 30.5 7.9 17.1 1.5 0.0 0.3 0.2 34.5 73.2 0.1 49.5 61.9 13.5 31.1 0.0 0.5 15.9 16.7 32.6 75.1 0.5 0.2 0.6 34.4 17.1 0.3 0.3 0.0 1.8 17.5 2.7 0.9 21.2 0.4 21.9 4.3 2.2 67.2 9.7 0.2 184.9 48.9 0.0 6.5 2.1 0.2 0.0 1.0 6.4 0.0 94.0 2.5 0.0 0.3 0.2 0.0 0.2 6.5 0.3 0.0 3.3 52.1 33.5 2.6 18.0 12.1 48.1 24.7 9.6 92.3 1.0 14.7 13.7 90.2 0.4 0.5 85.1 1.3 26.3 12.8 1.9 45.8 15.1 8.2 2.9 627.0 0.2 71.8 37.6 21.6 30.6 12.9 13.5 13.1 22.7 13.0 14.4 16.3 14.8 14.9 14.7 13.9 17.1 35.1 16.0 10.7 0.0 48.4 13.8 1.2 1.3 0.0 0.2 11.2 4.4 2.4 0.0 9.7 3.7 0.0 2.7 16.3 0.1 0.0 6.8 24.2 0.3 1.0 63.6 0.0 14.1 2.8 7.4 3.1 32.9 0.0 0.3 3.8 0.0 104.2 3.3 570.8 0.0 3.9 0.0 2.0 544.6 155.4 3.1 14.3 198.5 76.5 21.5 136.0 0.0 1.0 0.5 1.1 9.4 0.0 6.8 172.6 0.8 0.0 1.1 5.6 0.2 6.6 20.0 14.0 0.7 0.2 2.2 11.6 6.4 21.8 12.4 0.3 1.4 LYN JTK8 ENSG00000254087 "LYN proto-oncogene, Src family tyrosine kinase" P07948 8 55879835-56014169 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 73.8;lymphoid tissue: 85.4" "Cell type enhanced" "Detected in many" "B-cells: 237.5;Kupffer cells: 183.7;Macrophages: 226.0;monocytes: 182.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 64.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 198.4;HMC-1: 193.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001231, CAB004492" Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA 770000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus, Plasma membrane" Vesicles "CAB004492: AB_627897, HPA001231: AB_1079286" "unprognostic (7.87e-2)" "unprognostic (4.89e-2)" "unprognostic (9.04e-2)" "unprognostic (3.74e-1)" "unprognostic (8.12e-2)" "unprognostic (2.17e-1)" "unprognostic (5.70e-2)" "unprognostic (1.11e-1)" "unprognostic (2.79e-1)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (7.15e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (2.13e-1)" "unprognostic (2.72e-3)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" 17.2 7.3 3.9 79.2 4.0 73.8 9.2 7.4 8.7 11.0 7.8 14.2 36.3 6.2 4.8 8.6 10.0 23.5 5.4 4.4 5.5 5.9 14.9 28.2 49.2 9.4 7.2 3.6 9.5 6.3 4.8 23.5 8.3 5.6 13.3 8.9 17.0 9.7 1.6 3.7 31.6 14.2 7.2 85.4 13.3 3.1 9.0 10.4 10.6 4.4 53.1 29.7 5.7 11.2 47.2 24.6 6.9 0.7 0.5 0.0 43.6 34.6 54.7 21.0 15.7 18.0 15.5 41.2 15.0 12.1 15.3 19.3 22.2 23.8 14.6 70.0 19.8 198.4 6.9 5.5 4.0 20.6 193.4 0.8 7.8 0.6 13.6 13.1 27.2 0.0 98.3 90.2 3.0 3.3 0.1 21.5 38.6 72.9 2.1 3.3 9.6 5.0 9.8 24.9 4.5 74.8 17.3 0.1 7.5 44.9 3.4 41.4 33.1 0.0 10.0 0.1 15.0 26.4 13.2 102.4 1.5 38.8 1.7 4.5 12.2 22.7 1.6 28.3 1.3 15.9 0.3 0.6 10.3 16.1 0.2 0.7 64.4 4.3 49.1 16.2 0.0 5.0 3.9 4.0 7.4 8.7 4.4 5.5 9.4 7.2 8.3 7.2 9.0 11.2 21.0 35.3 37.5 27.7 237.5 5.4 23.8 32.4 4.6 6.3 10.3 7.0 2.2 18.6 44.5 9.2 2.1 2.9 130.0 14.5 0.0 21.8 0.9 14.6 26.2 28.1 6.0 40.4 1.1 53.0 65.2 13.6 18.8 15.9 72.8 0.5 22.9 13.2 126.6 0.0 2.5 14.1 14.2 183.7 96.1 2.4 3.4 226.0 5.4 92.8 182.6 54.3 94.7 13.0 1.7 40.7 13.3 1.2 58.9 62.9 26.0 2.1 40.9 2.6 19.7 3.7 6.4 1.2 2.1 4.9 5.8 38.7 25.0 62.5 17.1 82.4 LYPD1 "LYPDC1, MGC29643" ENSG00000150551 "LY6/PLAUR domain containing 1" Q8N2G4 2 132643286-132671579 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 31.2;choroid plexus: 15.4;fallopian tube: 53.5;pituitary gland: 33.7" "Cell type enhanced" "Detected in some" "Ductal cells: 73.8;Exocrine glandular cells: 74.5;monocytes: 62.0;Oligodendrocyte precursor cells: 28.1;Pancreatic endocrine cells: 43.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 57.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 3.6" "Lineage enriched" "Detected in single" 22 "granulocytes: 3.6" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 41.6;HUVEC TERT2: 32.7;SK-MEL-30: 36.5;U-251 MG: 65.9;WM-115: 140.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA068333 Approved "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "Vesicles, Plasma membrane" "HPA068333: " "unprognostic (9.25e-2)" "unprognostic (7.45e-2)" "unprognostic (1.03e-1)" "unprognostic (1.44e-2)" "unprognostic (1.15e-1)" "unprognostic (2.07e-2)" "unprognostic (6.40e-3)" "unprognostic (5.60e-2)" "unprognostic (8.36e-3)" "unprognostic (1.05e-2)" "unprognostic (6.70e-2)" "unprognostic (2.86e-2)" "unprognostic (1.51e-2)" "unprognostic (1.43e-2)" "unprognostic (1.55e-1)" "unprognostic (1.03e-1)" "unprognostic (6.78e-2)" 0.6 0.8 24.8 0.3 27.1 0.4 0.8 19.5 25.5 0.3 15.4 8.1 0.1 0.9 0.1 1.5 53.5 1.2 0.8 24.2 29.2 5.9 1.0 1.0 0.6 29.9 30.0 1.3 5.1 0.3 33.7 0.0 27.7 0.7 0.2 1.6 5.5 0.1 0.3 0.3 1.6 0.6 27.3 0.3 0.9 0.7 31.2 2.2 0.9 0.1 1.0 0.8 0.6 21.5 0.4 8.6 11.6 0.2 0.0 0.0 0.0 1.9 1.5 6.3 1.4 0.6 1.1 0.0 18.3 5.1 3.0 7.2 0.0 0.0 2.9 0.1 1.8 0.0 4.0 0.0 0.0 0.0 0.2 0.0 0.1 41.6 0.0 1.7 32.7 0.0 0.0 0.1 0.0 0.8 0.0 0.0 11.1 0.2 3.3 0.0 0.0 0.0 15.1 0.2 1.1 2.3 1.8 0.2 36.5 26.8 0.1 0.3 1.5 0.7 17.4 5.9 65.9 0.1 0.0 0.1 10.0 0.0 140.5 0.6 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 27.1 19.5 25.5 24.2 29.2 29.9 30.0 27.7 27.3 31.2 21.5 0.7 0.0 0.0 8.1 0.2 0.1 0.1 0.4 0.0 1.6 2.0 0.9 0.2 2.8 0.2 5.5 0.0 0.0 0.0 0.5 1.9 73.8 5.6 1.4 0.1 0.2 1.8 0.0 0.8 74.5 0.0 2.2 0.0 0.9 0.0 0.1 0.4 0.0 0.1 15.2 4.7 0.0 0.0 0.8 0.7 9.3 4.1 0.1 0.0 0.0 62.0 1.4 0.0 28.1 4.4 43.4 0.0 0.0 0.0 0.1 0.1 4.8 0.3 0.8 0.0 0.2 3.9 2.6 2.1 0.3 0.0 0.0 0.1 0.0 0.1 0.1 LYPD3 C4.4A ENSG00000124466 "LY6/PLAUR domain containing 3" O95274 19 43460787-43465608 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 1066.8;skin 1: 669.3;vagina: 487.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 504.7;Squamous epithelial cells: 811.7;Suprabasal keratinocytes: 2306.1;Syncytiotrophoblasts: 715.8;Urothelial cells: 642.9" "Cancer enhanced" "Detected in many" "cervical cancer: 158.5;head and neck cancer: 235.7" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 5.5" "Group enriched" "Detected in many" 9 "dendritic cells: 2.6;granulocytes: 2.1;T-cells: 5.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 42.5;HaCaT: 99.5;MCF7: 114.2;RT4: 108.2;SK-BR-3: 158.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041529, HPA041797, HPA077859" Enhanced Approved "Endoplasmic reticulum,Vesicles" NA NA 7600000 "Cluster 32: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Endoplasmic reticulum, Vesicles" "HPA041529: AB_2677534, HPA041797: AB_2677679, HPA077859: " "unprognostic (1.07e-1)" "unprognostic (1.42e-1)" "unprognostic (1.45e-1)" "unprognostic (1.13e-2)" "unprognostic (2.80e-1)" "unprognostic (2.67e-2)" "unprognostic (4.90e-3)" "prognostic unfavorable (7.86e-5)" "unprognostic (1.20e-1)" "unprognostic (6.99e-2)" "unprognostic (1.61e-1)" "unprognostic (5.09e-1)" "unprognostic (1.07e-3)" "unprognostic (5.13e-2)" "unprognostic (8.79e-2)" "unprognostic (1.11e-1)" "unprognostic (2.96e-3)" 1.7 3.5 0.7 1.7 0.8 6.6 32.1 0.6 1.0 259.1 1.4 1.1 0.5 7.6 1.8 1066.8 3.5 1.3 1.3 0.7 0.9 2.9 1.2 1.6 2.6 0.7 0.8 8.9 1.3 1.8 2.3 12.3 0.7 11.9 0.7 1.0 183.3 1.3 2.8 669.3 1.6 0.8 0.7 2.1 3.3 1.1 0.8 12.2 1.2 0.2 131.9 55.0 487.0 0.7 38.6 0.6 0.2 0.6 0.3 0.0 15.3 1.5 3.9 1.4 1.9 0.5 42.5 0.4 1.7 1.1 5.6 99.5 0.2 4.4 0.7 0.0 0.3 0.7 4.5 0.8 0.4 0.0 0.9 1.7 37.2 0.2 0.3 1.7 0.0 3.1 0.2 0.1 0.1 114.2 0.9 0.0 0.2 24.3 8.3 0.5 0.0 0.2 1.0 108.2 0.1 0.3 0.5 158.9 1.8 4.7 17.7 0.1 0.0 0.0 0.7 0.5 0.7 0.6 3.0 0.1 0.1 0.2 0.1 0.0 0.3 0.0 0.8 0.0 1.1 0.1 2.9 1.1 2.6 0.0 5.5 4.7 2.1 0.0 0.0 0.3 0.9 1.2 0.7 0.8 0.6 1.0 0.7 0.9 0.7 0.8 0.7 0.7 0.8 0.7 0.9 0.0 1.1 0.0 1.3 504.7 102.5 161.2 111.0 0.7 66.6 38.0 0.6 2.8 72.6 14.7 0.0 96.5 2.1 0.9 1.9 1.6 0.1 4.5 4.4 7.5 0.0 0.4 0.0 0.2 87.2 18.1 3.6 24.5 5.7 0.5 0.0 0.3 14.0 3.3 0.1 2.2 24.4 0.3 139.8 0.0 0.6 23.2 147.7 0.0 0.7 4.5 0.0 0.0 0.2 4.7 0.2 0.4 0.0 40.4 0.3 0.7 5.7 0.5 0.0 1.5 10.5 0.1 0.9 811.7 2306.1 715.8 9.6 0.5 1.1 642.9 LZTS3 "KIAA0552, ProSAPiP1" ENSG00000088899 "Leucine zipper tumor suppressor family member 3" O60299 20 3162617-3173592 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 80.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Astrocytes: 17.9;Excitatory neurons: 52.5;Inhibitory neurons: 27.7;Oligodendrocyte precursor cells: 20.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 19.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031008, HPA031009" Approved Approved Vesicles NA NA "Cluster 6: Brain - Smell perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA031008: AB_10601610, HPA031009: AB_10670162" "unprognostic (4.09e-2)" "unprognostic (4.10e-2)" "unprognostic (1.55e-2)" "prognostic unfavorable (7.26e-4)" "unprognostic (1.15e-1)" "unprognostic (6.19e-3)" "unprognostic (2.14e-1)" "prognostic favorable (7.98e-4)" "unprognostic (3.31e-1)" "unprognostic (1.08e-1)" "unprognostic (4.57e-2)" "unprognostic (9.69e-3)" "prognostic favorable (5.92e-8)" "unprognostic (4.63e-2)" "unprognostic (1.85e-1)" "unprognostic (8.47e-2)" "unprognostic (1.38e-1)" 4.0 5.9 57.3 1.2 80.0 1.8 5.3 57.7 77.9 14.5 1.6 5.9 9.8 7.6 3.6 3.0 10.0 7.5 12.2 67.2 21.5 27.8 7.1 9.5 1.0 25.6 21.1 16.1 30.7 9.5 15.1 2.0 27.2 11.2 2.0 54.0 43.4 7.9 11.8 4.0 9.8 2.6 11.8 2.4 21.1 6.1 23.8 1.4 18.5 4.5 0.7 7.6 6.0 55.5 3.5 3.3 4.6 5.2 6.3 1.8 3.2 3.5 7.5 5.8 8.5 19.2 9.9 6.0 1.9 6.9 7.5 1.7 2.6 3.7 4.4 0.1 3.3 0.2 0.7 15.9 14.2 0.3 1.6 2.3 8.1 8.1 3.1 2.1 0.9 5.5 3.5 1.9 2.8 1.6 0.5 0.7 10.4 8.2 3.2 1.6 1.5 6.6 7.4 1.3 18.1 5.6 2.9 4.0 2.8 6.7 9.5 0.2 5.4 6.2 11.7 2.5 1.1 3.7 0.6 1.8 3.0 1.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 57.3 80.0 57.7 77.9 67.2 21.5 25.6 21.1 27.2 11.8 23.8 55.5 2.6 19.2 10.3 17.9 1.3 1.5 0.0 3.3 0.0 0.0 7.4 6.3 16.6 0.0 12.9 11.0 0.0 1.6 0.4 0.9 11.7 4.9 0.0 9.7 5.7 1.6 1.8 0.0 52.5 5.1 0.4 3.7 0.0 11.9 0.0 2.2 0.0 0.0 0.3 0.0 27.7 0.0 6.1 0.0 1.1 0.0 0.0 0.5 3.6 3.7 0.0 0.0 0.0 20.6 7.1 8.2 0.0 0.0 0.3 0.0 0.0 11.2 11.3 0.0 0.0 0.0 3.0 0.0 0.0 0.0 1.0 1.6 0.5 1.5 0.6 0.0 MAF1 DKFZp586G1123 ENSG00000179632 "MAF1 homolog, negative regulator of RNA polymerase III" Q9H063 8 144104461-144107611 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024821, HPA058548" Uncertain Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Nucleoli, Vesicles" "HPA024821: AB_2671696, HPA058548: AB_2683751" "unprognostic (2.26e-1)" "unprognostic (3.05e-1)" "unprognostic (2.71e-2)" "unprognostic (2.21e-1)" "unprognostic (8.51e-2)" "unprognostic (9.67e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (6.12e-2)" "unprognostic (4.92e-2)" "unprognostic (5.90e-3)" "unprognostic (9.42e-2)" "unprognostic (6.48e-2)" "unprognostic (9.40e-3)" "unprognostic (9.02e-2)" "unprognostic (2.59e-1)" "unprognostic (2.38e-1)" "unprognostic (3.99e-2)" 96.2 84.4 86.6 61.7 89.7 164.4 92.4 87.3 98.3 97.1 82.5 186.9 62.1 101.9 63.6 81.8 93.3 63.0 193.4 83.5 82.7 89.8 61.1 78.0 78.6 91.2 87.6 110.3 84.6 87.4 71.0 65.1 86.4 103.6 58.3 35.4 77.5 94.6 413.1 69.6 92.2 80.5 85.3 96.5 102.1 76.4 88.7 90.8 78.6 294.7 69.5 130.7 84.1 90.5 119.8 187.1 85.4 86.3 229.0 113.3 68.9 91.8 151.0 140.5 142.1 69.2 129.1 131.0 150.4 154.9 78.1 71.4 117.4 129.9 103.0 115.4 139.5 144.5 127.8 109.6 154.1 62.0 94.4 100.7 150.0 112.8 211.4 156.7 153.6 94.1 112.5 86.9 85.0 281.2 230.9 112.3 64.0 216.3 490.2 90.3 119.7 141.8 89.0 88.8 123.8 102.2 122.0 156.7 152.6 79.5 106.7 93.9 93.0 65.0 146.0 116.1 117.5 102.7 86.0 62.2 107.8 113.7 44.0 50.4 98.0 126.5 72.8 76.1 81.0 110.2 105.0 117.5 107.6 129.9 110.9 105.0 52.9 93.1 78.4 81.0 84.1 111.9 86.6 89.7 87.3 98.3 83.5 82.7 91.2 87.6 86.4 85.3 88.7 90.5 76.8 16.0 15.6 6.8 95.2 92.9 92.4 51.6 53.5 41.4 76.5 77.8 54.2 42.9 24.8 44.1 14.6 106.4 113.9 82.6 105.7 101.1 86.1 30.0 39.3 69.7 93.3 129.0 5.0 107.9 103.6 66.3 28.5 43.6 32.5 77.3 67.5 29.3 97.6 37.0 5.5 89.7 32.6 72.3 85.6 41.0 88.3 84.9 78.2 6.5 138.0 82.0 138.0 7.1 10.7 106.0 97.4 93.3 60.3 170.3 155.0 110.2 12.9 37.6 98.6 65.5 84.8 96.1 43.3 54.0 89.8 144.3 87.6 72.4 88.5 122.4 MAK16 "MAK16L, RBM13" ENSG00000198042 "MAK16 homolog" Q9BXY0 8 33485182-33501262 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044417, HPA050574" Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoli, Vesicles" "HPA044417: AB_2678935, HPA050574: AB_2681181" "unprognostic (2.10e-1)" "unprognostic (1.74e-1)" "unprognostic (8.48e-3)" "unprognostic (2.28e-2)" "unprognostic (1.72e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.00e-4)" "unprognostic (2.07e-1)" "unprognostic (1.62e-1)" "unprognostic (4.00e-2)" "unprognostic (3.08e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (3.66e-4)" "unprognostic (8.04e-2)" "unprognostic (1.20e-1)" "unprognostic (6.74e-2)" "unprognostic (1.47e-1)" 9.9 6.2 4.7 9.3 4.8 9.2 8.9 5.1 5.7 6.6 4.1 5.7 5.4 7.2 5.1 8.0 5.9 6.5 7.0 4.5 6.4 7.2 9.0 5.6 11.1 5.3 6.3 7.5 9.3 5.9 4.5 7.8 5.8 6.1 6.5 4.0 5.6 5.6 8.4 7.4 5.0 7.7 5.3 6.5 5.4 5.6 5.5 8.8 8.5 8.0 10.8 12.2 5.1 6.0 14.1 19.3 13.2 30.6 15.2 18.1 19.9 25.0 16.2 26.4 24.6 28.5 12.0 49.7 23.8 22.1 22.5 18.3 45.6 27.8 35.0 10.8 12.3 46.9 13.2 25.6 22.9 19.3 27.4 19.1 24.8 34.8 40.4 9.4 19.6 33.5 59.5 27.5 22.0 16.1 68.9 22.4 71.4 34.4 13.2 23.9 20.1 22.2 22.2 23.7 33.6 26.7 15.5 21.1 30.4 16.2 14.7 19.5 17.8 24.9 19.3 32.6 28.9 13.8 16.4 50.4 15.3 39.7 27.0 0.0 2.4 0.6 3.2 5.0 3.6 2.0 3.2 2.8 2.9 2.5 4.0 4.3 0.4 4.4 7.9 3.0 2.6 2.3 4.7 4.8 5.1 5.7 4.5 6.4 5.3 6.3 5.8 5.3 5.5 6.0 12.8 16.0 9.7 3.6 12.8 15.6 15.2 5.6 13.1 5.1 7.9 9.0 12.9 10.0 11.3 9.2 2.1 11.5 7.8 3.9 7.9 10.6 1.8 9.8 19.8 12.7 1.8 15.8 5.8 7.8 15.8 15.8 8.2 10.5 9.5 10.8 5.3 7.3 8.7 10.1 6.0 6.7 6.1 5.3 4.7 1.3 9.0 7.8 1.8 2.8 7.7 2.9 10.3 7.1 4.7 11.5 5.0 7.5 12.1 15.3 4.1 10.2 10.5 5.1 6.6 17.6 14.4 13.8 19.2 12.7 14.9 7.5 9.9 13.8 7.4 12.3 MAN1B1 "ERManI, MANA-ER, MRT15" ENSG00000177239 "Mannosidase alpha class 1B member 1" Q9UKM7 9 137086985-137109183 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051516 Approved Uncertain Vesicles NA NA 940000 "Cluster 27: Non-specific - Gene expression" "Cluster 35: Non-specific - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA051516: AB_2681518" "unprognostic (1.21e-2)" "unprognostic (4.66e-1)" "unprognostic (1.25e-3)" "unprognostic (4.67e-3)" "unprognostic (2.27e-1)" "unprognostic (3.70e-3)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.59e-1)" "unprognostic (6.67e-2)" "unprognostic (1.79e-2)" "unprognostic (5.93e-3)" "unprognostic (1.75e-1)" "unprognostic (3.55e-2)" "unprognostic (2.28e-1)" "unprognostic (5.85e-2)" "unprognostic (2.37e-1)" "unprognostic (1.44e-3)" 25.3 32.2 21.3 12.1 21.2 9.1 25.1 21.1 32.9 22.6 26.3 24.1 15.5 20.7 20.4 32.1 22.0 20.1 27.3 22.4 23.1 31.8 39.6 23.0 15.4 22.6 22.7 28.0 36.0 20.0 32.6 21.4 25.2 26.1 9.9 3.6 34.2 15.2 17.6 32.6 22.9 12.1 21.7 28.7 25.6 28.3 22.9 13.8 27.1 9.9 10.1 22.0 21.9 22.8 22.8 50.7 18.2 49.9 67.0 57.7 57.0 37.9 78.4 48.6 43.7 24.9 67.4 20.0 118.8 64.7 69.2 74.3 11.0 36.3 9.1 27.7 17.3 8.7 41.2 33.2 59.6 16.0 33.1 65.1 66.9 29.1 25.1 67.1 32.4 26.5 24.5 32.7 36.4 45.0 16.7 37.8 23.5 67.3 50.0 9.7 30.6 63.9 41.6 11.3 20.4 18.3 55.2 55.9 38.7 9.6 63.5 31.5 46.5 69.6 25.9 52.9 43.6 13.0 11.1 13.3 84.6 19.9 61.6 17.9 31.2 27.0 32.4 34.4 30.2 19.1 25.1 30.4 36.0 16.4 24.3 25.0 9.0 31.0 42.2 26.6 34.5 32.1 21.3 21.2 21.1 32.9 22.4 23.1 22.6 22.7 25.2 21.7 22.9 22.8 18.8 19.2 27.3 23.5 18.3 11.6 12.6 33.0 12.0 20.7 23.5 21.7 10.3 14.3 21.5 25.8 16.7 53.2 24.3 39.1 7.9 32.0 5.8 21.5 16.4 19.7 30.5 14.3 13.0 32.0 72.4 26.9 23.4 20.3 21.0 47.8 25.0 25.2 32.1 30.3 10.2 28.1 22.4 22.9 17.4 6.8 21.1 21.8 23.2 11.2 29.3 16.0 16.5 6.6 12.8 27.6 25.0 21.8 25.4 9.0 35.9 15.9 24.9 19.3 13.1 19.4 20.2 16.1 28.4 16.3 16.2 45.4 21.5 41.1 25.6 8.2 MAN1C1 HMIC ENSG00000117643 "Mannosidase alpha class 1C member 1" Q9NR34 1 25616791-25786206 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 54.2;Excitatory neurons: 72.8;Hepatic stellate cells: 63.9;Hepatocytes: 57.8;Inhibitory neurons: 65.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 4.7" "Lineage enriched" "Detected in single" 5 "T-cells: 4.7" "Cell line enhanced" "Detected in many" "AF22: 30.5;HSkMC: 108.9;U-266/70: 31.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048352 Uncertain Uncertain Nucleoplasm,Vesicles NA NA 1800000 "Cluster 32: T-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Vesicles" "HPA048352: AB_2680368" "unprognostic (2.75e-1)" "unprognostic (5.45e-3)" "unprognostic (5.71e-3)" "unprognostic (2.05e-2)" "unprognostic (1.95e-1)" "unprognostic (8.90e-3)" "unprognostic (4.78e-2)" "prognostic favorable (7.55e-4)" "unprognostic (1.80e-1)" "unprognostic (5.70e-2)" "prognostic favorable (4.79e-4)" "unprognostic (2.51e-1)" "unprognostic (9.09e-3)" "unprognostic (3.18e-2)" "unprognostic (7.23e-2)" "unprognostic (7.44e-2)" "unprognostic (5.18e-2)" 12.5 11.6 13.3 9.4 15.2 2.2 6.2 16.6 16.1 19.6 27.3 10.0 4.5 14.5 7.5 7.0 9.7 18.6 10.1 15.9 16.9 25.4 29.6 9.2 12.4 45.1 23.2 17.3 3.6 24.0 17.1 21.1 26.1 17.6 4.6 11.0 5.7 17.9 4.6 8.1 6.1 19.9 29.4 19.3 7.3 4.2 16.4 10.5 26.0 5.5 9.4 12.3 9.1 37.8 0.1 0.4 30.5 6.4 22.4 17.2 8.6 0.4 5.8 1.4 0.4 0.6 0.2 0.1 0.3 2.3 3.9 0.4 3.0 0.3 0.6 9.8 1.3 0.6 0.5 0.1 2.6 5.2 12.0 108.9 0.5 0.7 0.0 0.4 0.1 1.2 0.1 1.3 0.0 1.6 0.0 5.8 7.8 0.1 0.2 0.6 18.9 0.6 0.2 0.7 17.7 0.6 0.7 4.7 1.5 5.5 2.4 3.6 0.1 0.0 1.6 20.1 0.7 31.7 0.1 0.1 4.6 10.7 1.5 0.3 0.9 0.4 0.3 0.6 0.5 0.2 2.1 0.9 0.3 0.5 4.7 2.7 0.6 0.4 0.8 0.2 0.5 0.7 13.3 15.2 16.6 16.1 15.9 16.9 45.1 23.2 26.1 29.4 16.4 37.8 5.8 3.2 3.2 18.3 2.0 6.6 2.9 3.6 5.2 23.5 1.1 1.5 7.0 4.3 7.3 22.0 54.2 10.6 1.6 0.5 9.8 1.0 0.3 0.4 8.1 8.4 3.0 2.7 72.8 3.8 0.9 23.3 1.1 0.6 2.5 0.3 63.9 57.8 24.8 21.9 65.8 0.1 16.2 19.0 4.3 2.1 27.1 6.8 1.8 39.4 3.3 17.8 3.1 25.1 21.7 1.4 0.3 22.2 2.2 2.0 0.0 23.3 2.2 4.4 6.6 17.0 7.1 0.2 2.9 1.0 5.3 42.7 6.9 0.7 0.2 1.9 MAN2B1 "LAMAN, MANB" ENSG00000104774 "Mannosidase alpha class 2B member 1" O00754 19 12646511-12666742 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 32.8;Plasma cells: 78.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 201.8;intermediate monocyte: 178.8;myeloid DC: 158.8;non-classical monocyte: 138.4;plasmacytoid DC: 187.5" "Group enriched" "Detected in all" 5 "dendritic cells: 187.5;monocytes: 201.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041530, HPA053404" Supported Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 3200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Vesicles" "HPA041530: AB_10795639, HPA053404: " "unprognostic (6.63e-2)" "unprognostic (3.61e-1)" "unprognostic (2.20e-2)" "unprognostic (5.48e-2)" "unprognostic (3.81e-1)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (1.84e-2)" "unprognostic (9.55e-2)" "unprognostic (1.95e-1)" "unprognostic (2.79e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.94e-5)" "unprognostic (4.00e-1)" "unprognostic (4.17e-2)" "unprognostic (2.22e-1)" "unprognostic (1.51e-1)" 35.8 21.4 5.3 54.6 6.4 83.6 24.8 6.6 5.9 19.6 18.5 30.3 31.0 21.8 9.0 19.8 19.9 28.4 16.0 4.9 7.4 17.3 23.7 46.8 52.1 10.3 6.7 16.7 39.7 16.6 9.9 24.6 9.5 20.5 22.6 1.6 35.2 14.9 12.1 28.9 33.6 20.2 8.9 70.1 32.7 6.4 9.7 23.1 16.3 9.4 39.3 35.6 16.7 12.4 52.4 26.3 26.4 31.3 85.8 57.3 74.0 37.9 79.2 33.1 32.4 21.3 21.4 56.9 44.9 30.4 9.4 40.1 13.6 25.6 15.7 28.5 41.6 19.8 13.6 34.9 43.5 131.6 130.2 68.5 49.2 18.5 23.3 35.6 31.7 21.1 25.6 41.9 17.8 40.9 17.9 74.2 21.9 26.2 32.8 40.8 36.1 28.8 38.9 59.8 8.2 25.5 37.7 32.0 63.0 15.8 49.4 80.0 42.0 44.8 18.4 44.0 36.2 55.4 65.5 28.0 30.4 127.5 51.2 12.2 201.8 29.7 31.9 178.8 35.4 32.9 28.9 29.0 158.8 26.4 15.4 15.9 29.4 13.2 138.4 187.5 30.7 150.3 5.3 6.4 6.6 5.9 4.9 7.4 10.3 6.7 9.5 8.9 9.7 12.4 1.6 6.4 7.5 8.5 25.1 3.6 2.0 2.7 14.2 2.6 1.9 1.0 0.9 2.8 2.0 1.8 0.0 2.5 20.5 2.0 1.9 1.7 3.7 1.4 2.5 3.1 1.8 9.4 7.8 2.3 2.8 7.2 20.9 1.3 1.3 3.4 1.8 0.8 8.4 0.0 6.4 0.9 0.0 15.4 24.7 11.1 3.7 32.8 1.8 17.8 11.0 1.5 9.2 3.5 13.4 1.5 2.5 4.5 78.1 2.5 3.8 1.5 3.9 4.0 13.1 2.3 2.0 0.6 1.6 11.5 3.3 2.7 9.4 2.7 2.0 2.0 MANBA ENSG00000109323 "Mannosidase beta" O00462 4 102630770-102760994 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Macrophages: 74.0;Microglial cells: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 16.6" "Group enriched" "Detected in many" 5 "dendritic cells: 5.3;granulocytes: 16.6;monocytes: 9.1" "Cell line enhanced" "Detected in many" "ASC diff: 15.5;hTCEpi: 13.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053478 Approved Supported Vesicles NA NA 15000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 57: B-cells - Immune response" Vesicles "HPA053478: AB_2682165" "unprognostic (2.29e-2)" "unprognostic (1.40e-1)" "unprognostic (3.80e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (7.56e-5)" "unprognostic (4.11e-2)" "prognostic unfavorable (3.74e-6)" "unprognostic (1.32e-1)" "unprognostic (2.19e-1)" "unprognostic (4.87e-2)" "unprognostic (7.78e-2)" "unprognostic (1.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.75e-2)" "unprognostic (7.12e-2)" "unprognostic (4.81e-2)" "unprognostic (2.13e-1)" 7.1 12.4 1.9 1.5 2.4 7.0 6.4 4.7 2.2 6.5 2.2 6.7 1.6 6.1 0.2 3.8 6.3 1.3 6.6 1.1 2.1 4.8 4.7 10.5 2.1 3.8 2.9 8.8 8.3 3.0 5.0 3.7 4.7 4.3 1.1 2.7 8.9 2.0 3.0 4.5 8.5 2.4 3.0 12.0 9.1 1.6 3.5 1.2 7.1 0.1 2.0 8.1 5.8 3.7 2.9 1.4 0.6 1.6 15.5 12.1 0.9 1.1 6.9 1.8 4.1 1.7 1.0 3.6 1.4 2.7 3.9 1.0 3.0 2.2 1.1 2.2 0.7 3.0 1.1 0.7 2.7 2.8 8.2 3.7 13.7 7.6 3.4 8.9 3.0 1.2 3.6 2.0 3.4 1.4 2.0 2.3 1.3 1.9 1.1 1.9 1.6 0.6 3.4 2.3 1.4 0.5 1.4 1.9 1.5 5.4 4.5 1.8 0.2 2.0 1.3 9.3 1.2 1.3 5.8 0.5 3.1 1.5 1.6 4.0 6.8 16.6 0.4 6.1 0.7 1.7 0.0 0.7 5.3 2.1 0.4 0.6 6.1 1.8 9.1 1.2 0.5 3.1 1.9 2.4 4.7 2.2 1.1 2.1 3.8 2.9 4.7 3.0 3.5 3.7 6.4 32.1 35.6 24.5 45.4 5.9 8.4 13.2 12.0 6.2 11.6 8.1 14.6 14.3 13.5 9.2 6.2 42.3 14.3 5.1 1.9 8.1 2.8 6.9 6.9 8.1 1.8 19.7 36.4 2.7 7.3 13.8 25.5 12.8 34.8 5.5 10.4 17.7 43.6 6.7 66.5 10.5 2.0 58.5 29.6 1.6 9.0 74.0 0.0 111.5 52.8 5.2 17.5 31.2 66.8 5.5 17.3 19.9 17.5 7.5 5.2 9.8 5.8 7.5 0.0 10.8 6.7 0.2 1.4 12.6 4.5 22.6 16.9 12.6 11.2 9.7 MANSC1 "FLJ10298, LOH12CR3" ENSG00000111261 "MANSC domain containing 1" Q9H8J5 12 12326056-12350242 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 70.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 15 "neutrophil: 98.3" "Lineage enriched" "Detected in many" 39 "granulocytes: 98.3" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 50.7;OE19: 54.3;RPTEC TERT1: 25.9" "Low region specificity" "Detected in all" "HPA007955, HPA007956" Approved Approved "Golgi apparatus,Vesicles" NA NA 44000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus, Vesicles" "HPA007955: AB_1079306, HPA007956: AB_1079305" "unprognostic (5.41e-3)" "unprognostic (3.10e-2)" "unprognostic (1.24e-1)" "unprognostic (5.46e-3)" "unprognostic (9.64e-2)" "unprognostic (1.29e-2)" "unprognostic (1.63e-2)" "unprognostic (8.47e-2)" "unprognostic (9.18e-2)" "unprognostic (5.20e-2)" "unprognostic (2.06e-2)" "unprognostic (3.03e-1)" "prognostic favorable (3.30e-5)" "unprognostic (1.15e-2)" "unprognostic (4.46e-2)" "unprognostic (3.65e-1)" "unprognostic (1.03e-2)" 18.9 12.1 3.4 4.3 4.1 3.5 19.5 3.9 6.5 16.9 5.0 22.9 11.7 22.1 11.5 42.3 16.6 10.2 11.2 4.1 3.0 13.2 9.7 12.3 2.3 3.2 3.3 11.3 25.2 11.3 17.9 9.5 3.2 15.1 15.8 5.4 70.0 10.8 4.0 21.7 15.2 12.1 2.6 11.3 21.5 8.4 3.8 1.4 13.8 4.4 6.4 16.3 20.6 4.0 0.3 5.7 1.8 0.1 5.6 5.5 6.2 3.9 4.6 2.0 2.5 4.8 18.2 0.0 4.2 3.9 2.1 0.8 7.1 3.3 1.5 0.0 6.9 8.3 6.4 4.2 0.9 1.4 2.3 3.5 5.3 1.3 0.9 13.8 50.7 0.1 5.6 0.1 0.6 11.0 0.0 0.6 6.5 54.3 3.0 0.2 0.0 0.1 25.9 18.8 2.6 10.3 2.1 16.9 6.0 2.8 15.4 5.0 20.5 2.8 2.3 0.7 5.5 0.4 0.2 2.8 2.0 0.0 2.1 6.6 1.2 1.0 0.1 0.9 0.0 0.2 0.3 0.0 0.6 0.4 2.5 0.4 98.3 0.6 0.4 0.1 0.0 0.6 3.4 4.1 3.9 6.5 4.1 3.0 3.2 3.3 3.2 2.6 3.8 4.0 29.0 9.6 21.2 8.8 3.3 4.0 7.1 7.2 6.2 6.1 21.2 13.5 2.6 28.6 11.9 23.9 8.4 35.4 4.5 33.6 1.9 19.0 0.9 15.1 5.2 28.8 21.7 3.6 16.6 37.9 7.4 10.4 23.0 20.5 2.5 8.6 37.1 9.8 8.0 10.1 13.5 33.4 8.2 5.5 0.7 2.2 13.7 2.0 0.0 15.0 2.7 11.4 9.2 7.5 11.4 16.3 25.2 16.6 1.0 7.4 16.7 3.0 18.1 13.1 0.0 4.8 6.5 2.1 1.5 22.1 4.7 17.0 3.0 9.7 26.5 8.8 MAP11 "C7orf43, FLJ10925, TRAPPC14" ENSG00000146826 "Microtubule associated protein 11" Q8WVR3 7 100154420-100158723 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 7.0;Extravillous trophoblasts: 7.2;Hofbauer cells: 7.7;Syncytiotrophoblasts: 19.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019359, HPA029463, HPA029464" Approved Enhanced "Vesicles,Plasma membrane,Centriolar satellite" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "Plasma membrane, Centriolar satellite" "HPA019359: AB_1848677, HPA029463: AB_10600001, HPA029464: AB_10600205" "unprognostic (1.57e-2)" "unprognostic (1.24e-1)" "unprognostic (6.19e-3)" "unprognostic (2.59e-1)" "unprognostic (5.23e-2)" "unprognostic (1.06e-1)" "unprognostic (9.36e-3)" "unprognostic (5.68e-3)" "unprognostic (6.97e-3)" "unprognostic (1.25e-1)" "prognostic favorable (6.19e-5)" "unprognostic (2.42e-2)" "unprognostic (1.85e-2)" "unprognostic (4.26e-2)" "unprognostic (2.81e-1)" "unprognostic (3.26e-1)" "unprognostic (6.54e-3)" 7.5 13.3 9.4 16.7 9.6 11.9 8.4 9.6 10.7 9.7 7.4 20.0 14.2 11.8 6.4 15.9 9.5 7.1 7.3 10.4 12.1 16.6 17.2 10.7 20.7 11.5 11.4 6.7 13.8 17.6 17.9 7.3 12.3 12.8 11.5 4.9 15.3 8.4 5.6 25.0 22.5 5.7 7.0 32.2 17.8 30.3 12.0 13.9 15.5 3.8 12.4 9.4 10.9 9.4 7.6 9.7 11.1 18.8 6.8 3.7 12.5 13.9 10.8 9.4 6.8 7.6 8.8 9.6 12.4 10.5 14.6 14.4 5.3 11.0 3.6 18.1 10.6 7.3 13.5 6.7 8.1 9.0 32.1 7.5 7.4 9.1 7.0 6.8 8.3 9.7 15.9 16.9 12.4 23.6 20.7 19.3 12.4 14.0 13.9 12.3 5.1 10.7 8.2 8.6 14.0 14.8 12.5 35.7 7.6 7.3 7.2 10.7 11.5 18.6 15.7 24.7 10.9 24.8 25.4 9.7 10.5 12.3 20.2 0.6 0.3 1.4 0.6 0.6 0.5 0.2 0.8 0.6 0.2 0.6 0.4 0.7 1.9 0.2 0.6 0.2 0.0 0.2 9.4 9.6 9.6 10.7 10.4 12.1 11.5 11.4 12.3 7.0 12.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 7.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 MAP1LC3A "ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3" ENSG00000101460 "Microtubule associated protein 1 light chain 3 alpha" Q9H492 20 34546854-34560345 "Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 674.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 85.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 85.4" "Cell line enhanced" "Detected in many" "HHSteC: 57.5;HSkMC: 71.2;SK-BR-3: 62.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007649, CAB037174, HPA042824, HPA052474, HPA052484" Enhanced Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "CAB037174: AB_1079382, HPA007649: AB_1853943, HPA042824: , HPA052474: AB_2681844, HPA052484: AB_2681846" "unprognostic (6.10e-3)" "unprognostic (8.03e-2)" "unprognostic (1.02e-1)" "unprognostic (1.99e-2)" "unprognostic (4.56e-3)" "unprognostic (1.06e-2)" "unprognostic (1.55e-1)" "unprognostic (1.79e-1)" "unprognostic (4.78e-2)" "unprognostic (1.98e-1)" "prognostic favorable (5.31e-5)" "unprognostic (2.82e-2)" "unprognostic (1.59e-3)" "unprognostic (3.84e-1)" "unprognostic (1.35e-1)" "unprognostic (7.90e-2)" "unprognostic (2.76e-1)" 53.0 26.6 120.8 13.7 122.1 16.4 40.6 114.4 177.2 49.6 69.7 56.3 30.6 44.9 17.8 22.6 41.7 23.9 81.7 123.7 148.4 54.2 53.2 39.4 28.1 137.1 135.6 38.3 24.8 23.7 84.8 12.4 155.9 46.6 19.7 31.6 31.0 20.3 54.7 64.8 44.9 19.1 101.2 22.0 36.6 52.8 116.2 6.9 52.9 34.1 30.4 39.1 43.5 123.3 0.0 7.0 4.2 0.0 28.4 37.3 0.2 26.1 21.9 16.3 14.9 0.1 0.5 0.0 0.3 21.3 39.5 4.8 0.1 8.1 3.2 6.2 2.0 0.1 17.2 0.0 57.5 0.0 14.0 71.2 1.4 11.4 4.9 0.1 13.5 0.0 0.0 0.1 17.4 0.0 0.2 0.5 1.6 5.3 5.2 0.0 0.0 0.0 0.0 0.0 41.4 31.9 29.6 62.2 0.0 16.3 0.3 22.7 20.5 45.2 0.4 9.8 11.2 0.0 6.5 0.0 29.4 0.0 16.1 4.0 3.2 11.0 5.1 4.8 3.7 9.4 5.5 5.4 1.0 6.0 1.7 3.4 85.4 3.3 1.7 4.5 12.1 2.9 120.8 122.1 114.4 177.2 123.7 148.4 137.1 135.6 155.9 101.2 116.2 123.3 107.4 0.0 6.6 19.2 18.3 57.7 123.0 50.5 12.5 127.2 41.9 57.8 25.4 41.5 27.1 46.0 85.5 25.7 26.1 67.3 113.5 42.0 137.3 98.4 78.4 64.4 165.1 3.6 48.4 23.5 15.8 75.4 34.1 90.6 18.4 90.8 75.7 44.6 37.9 70.7 58.8 70.5 136.3 16.1 47.1 674.0 95.1 17.5 62.2 14.0 21.0 98.7 7.2 12.5 54.6 44.7 82.5 108.7 10.1 146.3 149.4 120.0 40.7 127.7 138.1 77.7 119.3 53.0 21.6 5.8 51.4 211.8 26.4 79.8 76.7 98.1 MAP1LC3B ATG8F ENSG00000140941 "Microtubule associated protein 1 light chain 3 beta" Q9GZQ8 16 87383953-87404779 "Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037216, HPA042824, HPA052474, HPA052484, HPA053767" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Vesicles Nucleoplasm "CAB037216: AB_796155, HPA042824: , HPA052474: AB_2681844, HPA052484: AB_2681846, HPA053767: AB_2682253" "unprognostic (4.70e-3)" "unprognostic (2.89e-1)" "unprognostic (3.21e-1)" "unprognostic (9.70e-3)" "unprognostic (4.28e-1)" "unprognostic (1.79e-2)" "unprognostic (4.98e-3)" "unprognostic (2.50e-2)" "unprognostic (1.20e-1)" "unprognostic (7.26e-2)" "unprognostic (1.04e-1)" "unprognostic (1.70e-1)" "prognostic favorable (2.77e-7)" "prognostic unfavorable (8.97e-4)" "unprognostic (9.66e-2)" "unprognostic (1.14e-1)" "unprognostic (1.60e-1)" 92.0 82.9 108.4 37.5 112.9 245.6 72.9 123.7 135.3 46.1 110.7 46.2 25.5 52.6 44.7 45.0 48.2 57.0 102.7 105.2 130.1 71.3 50.3 50.9 52.5 131.5 132.0 43.3 37.1 74.2 51.1 75.6 140.8 43.6 47.1 125.9 49.2 49.3 195.2 62.5 36.9 66.6 120.5 44.4 42.3 51.8 126.5 54.9 63.5 176.7 51.4 57.3 42.0 123.8 56.9 33.7 63.8 59.2 188.5 145.3 41.9 111.4 130.1 88.0 59.9 56.0 42.4 37.7 82.0 155.7 97.5 50.8 95.2 72.3 125.3 49.9 81.0 39.4 40.2 94.4 313.4 28.3 40.0 194.9 234.8 137.0 326.0 131.1 101.1 57.2 107.4 79.0 150.4 61.5 48.4 64.0 66.1 27.7 81.2 76.2 42.2 37.6 119.0 28.4 53.0 60.3 174.8 29.4 230.8 85.2 48.0 34.0 134.1 94.7 59.7 86.4 65.3 99.4 131.5 137.7 133.9 68.3 69.6 312.5 86.8 198.1 78.6 81.6 80.5 72.5 75.8 81.1 69.2 58.2 58.4 62.0 214.3 104.7 85.3 75.1 108.2 109.2 108.4 112.9 123.7 135.3 105.2 130.1 131.5 132.0 140.8 120.5 126.5 123.8 523.1 89.8 90.5 15.7 185.3 221.0 203.1 176.2 301.7 70.4 183.9 227.3 180.7 72.9 117.2 77.3 52.1 130.6 242.7 309.1 262.2 310.9 222.1 283.6 235.9 191.7 132.2 364.2 29.2 134.8 140.2 177.7 96.4 530.5 131.1 49.3 80.7 70.1 206.4 87.5 41.4 137.3 238.0 150.9 268.5 269.7 90.7 262.2 188.5 19.7 207.0 194.3 143.2 14.6 26.9 322.8 407.6 89.1 202.0 209.3 217.4 236.9 133.5 124.0 59.2 129.5 168.2 361.2 206.7 221.8 213.5 631.5 221.6 85.7 122.4 294.5 MAP1LC3B2 ATG8G ENSG00000258102 "Microtubule associated protein 1 light chain 3 beta 2" A6NCE7 12 116548105-116576606 "Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 40.5;Langerhans cells: 33.4;Paneth cells: 63.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 7.2" "HPA042824, HPA052474, HPA052484, HPA053767" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles Nucleoplasm "HPA042824: , HPA052474: AB_2681844, HPA052484: AB_2681846, HPA053767: AB_2682253" "unprognostic (1.50e-1)" "unprognostic (6.94e-2)" "unprognostic (9.14e-2)" "unprognostic (3.89e-3)" "unprognostic (1.62e-1)" "unprognostic (1.22e-1)" "unprognostic (2.43e-3)" "unprognostic (3.15e-1)" "unprognostic (2.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.33e-1)" "unprognostic (1.84e-1)" "unprognostic (1.11e-3)" "unprognostic (6.66e-3)" "unprognostic (1.65e-1)" "unprognostic (1.53e-2)" "unprognostic (3.42e-1)" 1.8 2.2 0.3 0.7 0.4 3.9 1.5 2.0 0.6 0.7 0.8 0.9 1.2 1.3 1.2 1.8 1.0 1.6 2.4 0.3 0.8 1.3 1.1 1.2 1.1 0.5 0.6 1.4 0.8 0.1 0.9 0.7 0.7 0.8 1.5 0.9 1.2 0.0 4.2 1.6 1.4 1.5 0.5 0.8 0.8 1.1 0.4 0.7 0.9 0.5 1.5 0.8 0.9 0.7 1.4 0.7 1.5 1.8 0.4 0.5 1.6 2.8 0.2 0.0 0.1 2.7 2.0 1.1 1.8 0.2 3.4 1.0 0.4 0.3 0.5 1.0 1.9 0.6 2.7 4.9 0.9 0.9 1.0 0.1 0.4 0.9 0.7 3.9 1.9 1.2 3.3 3.0 0.3 2.7 1.0 1.9 0.8 1.2 2.6 1.4 0.2 3.6 0.2 1.5 1.5 2.3 1.9 0.6 7.2 2.8 1.0 0.4 0.7 2.6 0.9 2.2 1.4 2.2 3.3 3.6 3.9 1.4 1.3 38.6 11.6 34.2 7.8 11.8 7.2 9.0 8.8 7.9 9.4 7.7 6.1 7.0 43.5 9.8 14.2 9.6 15.9 13.6 0.3 0.4 2.0 0.6 0.3 0.8 0.5 0.6 0.7 0.5 0.4 0.7 1.9 0.0 1.7 10.7 4.0 24.2 17.3 6.1 0.0 1.5 1.1 2.5 40.5 1.5 4.6 0.0 0.0 2.5 2.8 22.7 7.9 0.2 12.3 2.8 2.2 8.0 1.8 24.0 4.4 0.0 2.4 8.3 0.0 5.9 7.0 0.9 2.5 2.0 4.5 13.5 8.6 7.5 12.2 7.2 33.4 14.2 4.7 5.5 10.6 1.0 2.4 0.5 7.2 4.0 1.7 0.4 63.1 3.8 0.1 12.5 2.5 8.1 3.1 1.1 0.0 9.0 8.0 20.8 11.5 0.0 21.5 11.4 8.2 0.8 5.9 21.8 MAP3K14 "FTDCR1B, HS, HSNIK, NIK" ENSG00000006062 "Mitogen-activated protein kinase kinase kinase 14" Q99558 17 45263119-45317029 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 33.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 40.6;U-251 MG: 43.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027269, HPA027270" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 59: Non-specific - Translation" "Cluster 9: U-2 OS - Unknown function" "Cluster 3: Monocytes - Immune response regulation" "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "HPA027269: AB_2732436, HPA027270: AB_2732437" "unprognostic (1.05e-2)" "prognostic favorable (5.27e-5)" "unprognostic (2.71e-2)" "unprognostic (9.42e-2)" "unprognostic (5.31e-2)" "unprognostic (2.61e-3)" "unprognostic (2.70e-2)" "unprognostic (1.72e-1)" "unprognostic (3.40e-1)" "unprognostic (3.45e-1)" "unprognostic (1.07e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.78e-4)" "unprognostic (8.82e-2)" "unprognostic (3.49e-2)" "unprognostic (1.03e-2)" "unprognostic (2.28e-1)" 5.9 4.7 2.6 12.5 5.0 5.2 6.4 2.9 2.3 7.1 2.8 15.6 8.1 5.7 1.9 7.8 6.6 5.9 9.9 3.2 2.7 5.1 7.3 8.1 17.7 3.6 4.6 6.0 8.3 4.6 5.9 2.7 3.1 7.0 5.2 2.2 8.1 4.7 28.0 8.5 10.3 5.9 2.5 12.4 7.6 6.9 4.8 13.4 5.8 9.9 16.0 7.2 7.1 2.1 17.1 40.6 3.6 6.5 2.4 7.1 9.4 4.5 3.4 14.9 9.1 5.5 21.0 7.4 24.1 5.3 14.6 11.6 1.5 6.5 7.6 24.3 3.1 1.4 10.1 2.1 7.1 1.1 6.9 10.0 3.6 7.3 3.6 15.6 3.0 3.2 2.7 30.1 8.1 6.1 6.8 1.7 1.8 11.1 5.1 9.5 12.1 17.9 10.5 2.6 3.5 3.0 7.6 3.4 5.0 5.5 2.8 0.4 5.6 6.5 10.2 5.7 43.1 29.1 12.1 4.1 3.9 4.0 9.2 0.0 2.0 0.8 1.6 1.8 1.0 4.2 1.1 1.0 1.4 4.4 1.2 0.9 1.6 2.0 0.6 1.7 2.9 1.6 2.6 5.0 2.9 2.3 3.2 2.7 3.6 4.6 3.1 2.5 4.8 2.1 5.8 3.2 12.8 23.5 15.3 0.0 14.7 0.0 14.8 4.5 5.6 4.8 2.3 18.6 2.5 0.0 4.2 0.9 14.5 13.9 0.0 4.8 4.7 7.0 4.0 6.1 13.1 1.3 8.9 2.7 1.5 6.3 10.2 5.6 1.3 2.1 6.4 9.2 4.9 1.7 15.6 7.8 0.0 9.4 0.0 6.2 4.7 11.3 0.0 26.2 33.4 1.9 5.2 6.6 5.5 3.3 9.6 1.2 8.5 6.2 13.4 3.8 5.1 2.9 0.0 12.9 2.8 4.2 3.0 7.9 0.0 0.0 10.6 2.4 8.5 6.8 MAP3K15 "ASK3, bA723P2.3, FLJ16518" ENSG00000180815 "Mitogen-activated protein kinase kinase kinase 15" Q6ZN16 X 19360056-19515261 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "adrenal gland: 10.8;choroid plexus: 13.1" "Cell type enhanced" "Detected in some" "Collecting duct cells: 5.5;Cone photoreceptor cells: 4.2;Granulosa cells: 7.5;Theca cells: 29.8" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.0;HAP1: 4.9;HEK 293: 4.1;JURKAT: 2.5;REH: 2.6;SuSa: 4.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA004006 Approved Vesicles NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Vesicles "HPA004006: AB_1079358" "unprognostic (2.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.21e-2)" "unprognostic (6.56e-8)" "unprognostic (3.47e-2)" "unprognostic (1.42e-2)" "unprognostic (2.19e-3)" "unprognostic (2.35e-2)" "unprognostic (1.46e-1)" "unprognostic (4.87e-2)" "unprognostic (1.30e-2)" "unprognostic (8.95e-2)" "unprognostic (2.77e-3)" "unprognostic (4.00e-1)" "unprognostic (2.37e-1)" "unprognostic (3.98e-2)" "unprognostic (8.20e-2)" 0.0 10.8 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 13.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.6 1.1 0.0 0.3 0.0 0.0 0.3 0.4 0.5 0.7 0.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.3 0.0 4.9 0.0 0.0 0.8 4.1 1.7 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.3 0.0 0.0 0.1 0.0 1.1 1.3 0.0 0.5 2.6 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.7 0.6 0.0 0.3 0.4 0.0 0.2 0.0 0.2 0.0 3.1 0.3 0.0 0.1 0.5 0.0 0.0 1.0 0.2 0.6 2.9 0.0 0.0 5.5 4.2 0.0 0.1 0.2 3.9 0.0 0.4 0.3 0.3 0.1 0.0 0.4 2.6 0.0 0.3 0.4 0.0 0.3 0.0 7.5 0.4 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.2 0.3 0.2 0.0 1.0 0.0 0.3 0.0 0.5 1.1 0.1 0.0 1.2 0.0 0.2 0.0 0.1 0.0 0.6 0.0 0.3 0.2 0.6 1.4 0.0 0.0 0.1 0.2 29.8 0.1 0.0 MAP4K2 "BL44, GCK, RAB8IP" ENSG00000168067 "Mitogen-activated protein kinase kinase kinase kinase 2" Q12851 11 64784918-64803241 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 46.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007330 Enhanced Approved Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" Vesicles "HPA007330: AB_1079361" "unprognostic (1.66e-1)" "unprognostic (2.83e-1)" "unprognostic (3.07e-3)" "unprognostic (4.37e-3)" "unprognostic (2.67e-1)" "unprognostic (9.23e-2)" "prognostic unfavorable (3.10e-5)" "unprognostic (4.51e-2)" "unprognostic (3.65e-1)" "unprognostic (5.28e-2)" "unprognostic (1.24e-2)" "unprognostic (1.41e-1)" "unprognostic (2.47e-2)" "unprognostic (2.97e-1)" "unprognostic (1.57e-2)" "unprognostic (1.82e-1)" "unprognostic (1.95e-2)" 5.0 3.9 8.9 6.9 7.2 15.5 4.1 9.8 9.9 4.6 4.9 5.6 3.3 4.8 2.5 2.7 3.8 4.2 4.3 7.6 7.0 5.4 2.0 9.7 17.6 7.8 8.0 3.4 5.0 3.2 5.8 8.9 8.1 4.7 3.0 5.3 6.6 5.8 2.5 3.5 8.9 3.7 6.6 18.0 5.2 4.6 9.7 7.4 7.0 1.5 14.2 4.6 3.5 8.8 9.4 8.4 5.4 9.8 4.7 2.9 12.7 7.0 6.5 8.2 5.8 3.7 4.3 16.4 12.6 8.0 14.5 2.8 6.5 6.8 4.9 21.5 3.1 28.9 12.0 7.9 5.8 15.3 10.4 2.9 3.4 6.4 4.1 5.7 20.3 28.0 2.5 1.5 2.5 11.8 9.2 15.2 3.6 5.6 11.2 18.8 0.6 18.9 4.6 4.7 6.4 9.3 6.0 7.8 6.4 6.1 15.5 23.2 15.8 6.8 15.0 6.3 2.9 1.8 3.8 18.1 6.0 22.8 5.1 2.2 4.3 5.9 4.9 12.5 4.9 9.9 6.5 4.4 4.4 6.6 7.7 6.0 8.0 2.5 15.8 5.0 9.5 7.3 8.9 7.2 9.8 9.9 7.6 7.0 7.8 8.0 8.1 6.6 9.7 8.8 21.6 3.2 4.8 6.8 32.9 1.3 2.8 1.8 6.2 20.6 8.1 10.4 4.7 7.2 2.4 1.8 25.0 7.6 9.4 6.8 3.9 1.7 33.8 2.6 3.8 20.0 6.0 5.0 5.9 1.7 11.3 4.9 9.2 6.0 1.3 7.7 24.3 2.0 11.0 11.8 4.6 1.8 6.1 8.9 3.1 46.8 4.1 16.2 1.8 18.7 13.4 7.2 14.4 2.0 7.2 0.9 16.2 7.2 15.6 1.8 1.6 3.6 1.5 14.6 6.6 3.7 4.3 2.1 13.8 5.2 1.4 5.1 19.9 22.6 2.2 2.0 MAPK8IP3 "JIP3, JSAP1, KIAA1066, syd" ENSG00000138834 "Mitogen-activated protein kinase 8 interacting protein 3" Q9UPT6 16 1706183-1770351 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 62.1;Horizontal cells: 87.5;Inhibitory neurons: 65.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005580, HPA041785, HPA069311" Approved Approved Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 57: B-cells - Immune response" Vesicles "CAB005580: AB_627840, HPA041785: AB_2677671, HPA069311: AB_2686116" "unprognostic (1.49e-1)" "unprognostic (2.22e-1)" "unprognostic (8.28e-3)" "unprognostic (8.32e-2)" "unprognostic (3.90e-1)" "unprognostic (6.83e-3)" "unprognostic (3.66e-2)" "unprognostic (2.41e-2)" "unprognostic (1.55e-1)" "unprognostic (8.67e-2)" "unprognostic (1.57e-2)" "unprognostic (6.91e-3)" "prognostic unfavorable (5.25e-5)" "unprognostic (2.84e-1)" "unprognostic (1.85e-1)" "unprognostic (2.45e-1)" "prognostic favorable (3.95e-4)" 25.1 32.2 29.3 13.5 36.5 26.4 26.1 16.2 64.9 38.6 0.0 26.9 13.5 25.9 4.0 20.2 31.7 7.9 39.3 39.7 18.5 34.1 30.8 31.7 16.3 39.5 17.4 46.8 39.3 7.0 78.6 8.5 34.9 43.6 3.8 11.3 28.8 7.4 22.1 37.0 39.4 4.4 7.9 49.8 25.9 32.0 18.4 11.8 38.3 4.3 6.5 35.2 30.5 44.9 6.5 12.2 12.7 11.4 6.1 10.3 9.9 10.7 4.0 5.2 4.6 17.3 21.0 7.5 6.6 6.7 3.7 12.1 3.1 7.0 1.7 11.9 14.1 10.0 33.6 13.4 8.4 6.5 16.9 20.7 9.2 7.6 3.7 22.9 6.9 14.1 8.6 14.1 5.5 16.6 10.2 28.5 8.5 3.2 6.9 44.1 6.3 12.9 6.4 8.4 26.4 21.0 12.8 11.8 5.3 5.8 6.4 9.1 21.9 21.8 12.2 9.4 8.6 31.4 5.8 9.7 5.7 6.7 11.1 0.0 0.2 0.5 0.2 0.0 0.1 0.3 0.0 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.1 29.3 36.5 16.2 64.9 39.7 18.5 39.5 17.4 34.9 7.9 18.4 44.9 9.1 3.2 7.8 46.7 30.5 9.8 4.3 10.0 13.1 40.8 7.9 7.5 6.6 10.0 10.5 3.7 37.5 5.6 10.4 16.8 1.9 4.9 24.9 13.2 13.0 7.8 10.2 8.6 62.1 3.8 5.7 7.5 34.7 21.9 1.3 23.4 6.4 9.7 7.2 87.5 65.2 11.1 10.2 10.3 12.5 23.4 7.8 13.5 7.2 31.9 8.7 11.9 9.2 32.6 52.8 7.7 9.5 9.1 17.6 4.7 10.3 1.2 15.9 19.2 6.6 7.3 8.2 19.8 5.1 10.8 9.7 5.6 11.8 5.9 11.7 6.0 MARCHF1 "FLJ20668, MARCH-I, MARCH1, RNF171" ENSG00000145416 "Membrane associated ring-CH-type finger 1" Q8TCQ1 4 163524298-164384050 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 31.6;retina: 27.5" "Group enriched" "Detected in some" 4 "B-cells: 21.4;Hofbauer cells: 46.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 94 "classical monocyte: 41.8;eosinophil: 25.5;intermediate monocyte: 41.0;memory B-cell: 42.3;myeloid DC: 44.2;naive B-cell: 35.8;non-classical monocyte: 45.4;plasmacytoid DC: 16.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 7.1;U-266/70: 7.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014600, HPA048024" Uncertain Supported "Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Vesicles "Endoplasmic reticulum, Golgi apparatus" "HPA014600: AB_1853573, HPA048024: " "unprognostic (7.29e-2)" "unprognostic (5.82e-2)" "unprognostic (1.48e-1)" "unprognostic (9.09e-2)" "unprognostic (8.25e-2)" "unprognostic (2.98e-2)" "unprognostic (4.79e-3)" "unprognostic (9.00e-2)" "unprognostic (3.00e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-1)" "unprognostic (2.20e-1)" "unprognostic (1.24e-1)" "unprognostic (7.00e-2)" "unprognostic (2.48e-2)" "unprognostic (2.70e-1)" "unprognostic (2.91e-2)" 6.4 3.5 7.8 21.5 8.1 3.9 2.7 3.6 7.7 3.1 1.8 3.5 3.9 2.5 0.7 3.0 2.8 5.3 1.7 6.6 10.1 1.8 4.1 8.0 31.6 8.0 8.2 2.7 2.8 0.8 2.5 9.9 6.9 2.3 4.5 27.5 3.2 1.2 1.0 4.5 7.0 6.2 7.0 25.8 3.9 1.7 12.1 5.6 2.1 1.0 25.5 7.7 2.9 14.4 0.6 0.5 2.1 1.2 0.0 0.0 1.3 0.9 0.0 0.0 0.0 1.2 2.4 7.1 2.5 0.0 0.2 1.0 0.0 0.0 0.0 0.8 0.7 5.0 3.0 0.5 0.0 3.1 1.6 0.0 0.0 0.0 0.1 2.8 0.0 1.3 1.9 3.6 2.4 0.7 1.8 1.9 2.6 0.2 0.9 2.0 0.3 0.5 0.1 1.1 1.0 0.9 0.6 1.0 0.4 1.4 2.9 0.5 2.3 0.8 1.4 0.5 1.7 7.0 2.5 1.9 0.9 1.5 1.1 0.0 41.8 25.5 0.1 41.0 0.0 42.3 0.1 0.0 44.2 35.8 0.0 0.0 0.3 0.3 45.4 16.5 0.0 18.4 7.8 8.1 3.6 7.7 6.6 10.1 8.0 8.2 6.9 7.0 12.1 14.4 0.1 0.0 0.0 0.0 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 46.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 MARCHF3 "MARCH-III, MARCH3, MGC48332, RNF173" ENSG00000173926 "Membrane associated ring-CH-type finger 3" Q86UD3 5 126867714-127030558 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Cytotrophoblasts: 43.8;Syncytiotrophoblasts: 98.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 10.5;naive B-cell: 12.1" "Lineage enriched" "Detected in many" 4 "B-cells: 12.1" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 40.4;HUVEC TERT2: 27.4;TIME: 33.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043406 Uncertain Supported Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA043406: AB_10793947" "unprognostic (5.96e-3)" "unprognostic (1.46e-2)" "unprognostic (1.91e-2)" "unprognostic (4.21e-2)" "unprognostic (9.00e-3)" "unprognostic (1.17e-2)" "unprognostic (7.75e-3)" "unprognostic (9.41e-2)" "unprognostic (8.93e-2)" "unprognostic (2.05e-3)" "unprognostic (3.15e-2)" "unprognostic (1.82e-1)" "unprognostic (5.60e-6)" "unprognostic (7.74e-2)" "unprognostic (7.64e-2)" "unprognostic (1.05e-1)" "unprognostic (3.64e-1)" 5.6 2.8 6.1 2.9 5.6 3.7 2.6 5.3 4.1 0.9 1.9 5.3 0.9 1.4 0.0 1.4 1.5 5.2 7.8 3.9 5.7 0.8 0.7 2.4 2.5 11.5 7.1 1.1 2.4 0.3 2.4 1.7 7.9 0.6 5.6 7.4 4.6 0.2 6.5 5.8 2.4 2.9 8.3 1.6 2.4 5.6 7.8 1.3 1.4 3.3 2.1 7.6 0.7 8.5 0.4 1.8 3.9 2.1 3.4 3.2 1.2 14.2 5.9 11.1 16.3 1.9 0.8 3.8 1.3 1.9 2.4 1.1 4.9 2.5 15.3 0.8 4.7 12.2 3.2 1.9 5.6 5.0 3.0 2.4 0.7 40.4 4.8 2.6 27.4 0.6 5.1 0.7 9.3 1.3 0.5 2.3 3.3 3.0 4.6 1.5 15.5 1.2 0.9 2.0 1.3 0.9 3.3 0.5 1.6 1.9 2.9 5.0 33.5 2.2 1.8 12.6 1.6 1.9 2.3 2.3 8.3 3.8 2.0 0.0 0.2 2.8 0.5 0.4 0.1 10.5 0.6 0.3 0.1 12.1 2.3 0.5 0.8 2.3 0.3 0.7 2.9 0.8 6.1 5.6 5.3 4.1 3.9 5.7 11.5 7.1 7.9 8.3 7.8 8.5 3.8 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.0 0.0 43.8 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 3.2 5.8 0.0 0.0 0.0 0.0 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 98.6 0.6 0.0 0.0 0.0 MARCO "SCARA2, SR-A6" ENSG00000019169 "Macrophage receptor with collagenous structure" Q9UEW3 2 118942194-118994660 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 94.9;lung: 199.6;lymphoid tissue: 87.9" "Cell type enriched" "Detected in many" 6 "Kupffer cells: 1269.8" "Cancer enhanced" "Detected in many" "lung cancer: 21.6" "Group enriched" "Detected in many" 4 "cerebral cortex: 4.1;thalamus: 12.6" "Group enriched" "Detected in some" 4 "classical monocyte: 33.7;intermediate monocyte: 56.5" "Lineage enriched" "Detected in many" 5 "monocytes: 56.5" "Cell line enhanced" "Detected in some" "HaCaT: 1.7;THP-1: 2.5;U-2 OS: 2.6;U-266/70: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA063793 Enhanced Approved "Golgi apparatus,Vesicles" NA NA 30000000 "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "Golgi apparatus" Vesicles "HPA063793: AB_2685123" "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" "unprognostic (5.96e-3)" "unprognostic (3.36e-2)" "unprognostic (1.71e-2)" "unprognostic (3.58e-2)" "unprognostic (3.67e-1)" "unprognostic (1.06e-1)" "unprognostic (2.95e-1)" "unprognostic (2.83e-1)" "unprognostic (6.27e-3)" "unprognostic (5.13e-2)" "unprognostic (2.24e-3)" "unprognostic (1.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.40e-1)" "unprognostic (6.55e-2)" 64.7 31.1 0.4 87.9 1.4 3.4 7.4 0.7 4.1 0.7 4.4 5.7 2.0 0.7 1.3 2.4 25.5 2.4 19.0 0.9 1.0 1.6 94.9 199.6 17.7 1.2 1.7 7.5 0.8 0.3 1.5 2.8 1.9 1.8 2.1 0.0 4.4 2.3 1.5 2.5 3.1 29.8 1.2 37.1 3.5 2.0 12.6 1.3 1.5 5.0 1.1 25.2 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.0 2.6 0.4 0.0 1.6 0.0 0.0 0.0 0.5 0.0 0.0 33.7 0.0 0.0 56.5 0.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.7 0.0 7.2 1.0 0.0 9.2 0.4 1.4 0.7 4.1 0.9 1.0 1.2 1.7 1.9 1.2 12.6 0.7 0.7 25.6 45.1 0.0 1.0 1.1 0.1 0.0 0.0 0.0 3.4 1.8 0.4 1.5 16.7 3.7 0.0 0.7 1.4 0.1 0.0 3.9 0.0 0.0 0.0 5.2 0.0 8.0 0.0 0.2 1.1 2.6 0.0 0.0 12.6 0.0 11.4 3.4 169.6 0.0 0.0 0.0 0.0 1269.8 46.4 0.1 0.0 199.3 0.0 2.8 23.2 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.5 0.1 0.0 0.2 13.1 0.0 0.0 0.5 0.2 0.0 0.3 0.0 0.9 1.9 4.1 0.0 0.0 0.1 MARF1 "KIAA0430, LKAP, LMKB, PPP1R34" ENSG00000166783 "Meiosis regulator and mRNA stability factor 1" Q9Y4F3 16 15594387-15643154 "Predicted intracellular proteins" "Differentiation, Meiosis, Oogenesis" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 28.7;Breast glandular cells: 26.3;Endometrial stromal cells: 27.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017992 Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" "Golgi apparatus, Vesicles" "HPA017992: AB_1852921" "unprognostic (2.33e-1)" "unprognostic (6.44e-3)" "unprognostic (8.84e-2)" "unprognostic (3.78e-2)" "unprognostic (1.28e-1)" "unprognostic (6.13e-3)" "unprognostic (2.35e-1)" "unprognostic (2.10e-2)" "unprognostic (2.47e-2)" "unprognostic (6.93e-2)" "unprognostic (8.44e-3)" "unprognostic (1.35e-1)" "unprognostic (6.94e-3)" "unprognostic (3.08e-2)" "unprognostic (1.24e-1)" "unprognostic (8.74e-2)" "unprognostic (7.94e-2)" 10.5 7.1 2.1 10.8 5.2 9.7 9.4 1.5 6.6 10.0 3.7 16.0 10.4 12.8 1.0 12.3 13.7 12.5 9.2 4.5 3.4 13.5 8.3 9.3 14.6 3.6 4.5 18.2 12.9 12.3 5.9 9.4 2.6 10.4 12.1 8.4 14.4 13.7 18.3 10.5 11.2 12.0 0.0 12.1 10.1 4.9 4.4 12.7 14.8 15.2 22.0 12.1 8.8 4.5 8.3 9.4 15.0 8.2 12.1 22.4 7.2 9.6 12.4 8.2 13.5 2.7 6.2 29.8 17.0 12.3 6.7 5.6 7.7 12.4 13.6 11.6 5.0 13.1 12.3 10.4 13.4 15.7 10.5 13.4 13.4 15.3 15.5 16.9 19.5 12.8 12.6 13.3 15.6 7.7 13.9 2.6 5.6 7.1 7.2 19.5 22.0 5.9 7.1 6.4 9.1 10.8 7.7 8.9 14.3 6.7 9.2 13.2 19.7 11.2 5.5 11.6 6.3 12.3 12.9 15.9 12.4 9.6 16.4 2.5 0.7 4.6 1.1 1.2 0.7 4.1 1.7 1.3 0.8 5.2 1.9 1.4 7.1 0.9 1.8 0.3 1.7 0.9 2.1 5.2 1.5 6.6 4.5 3.4 3.6 4.5 2.6 0.0 4.4 4.5 21.4 22.4 28.7 0.0 10.7 0.0 0.0 0.0 0.0 0.0 26.3 19.8 0.0 0.0 18.6 23.9 0.0 5.7 14.7 0.0 15.6 10.4 0.0 17.8 27.5 8.4 0.0 0.0 0.0 14.2 5.9 7.7 0.0 20.0 11.4 23.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 0.0 0.0 7.2 0.0 0.0 0.0 0.0 13.7 0.0 0.0 6.8 0.0 0.0 19.0 17.5 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 7.7 7.8 17.9 0.0 0.0 MARVELD3 MRVLDC3 ENSG00000140832 "MARVEL domain containing 3" Q96A59 16 71626161-71642114 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 150.1;Intestinal goblet cells: 68.2;Paneth cells: 102.9;Proximal enterocytes: 199.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "basophil: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 21.7;BEWO: 30.9;CACO-2: 23.6;CAPAN-2: 22.5;HaCaT: 21.4;MCF7: 40.8;RT4: 18.8;SK-BR-3: 18.5;T-47d: 26.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043514, HPA045471" Approved "Vesicles,Intermediate filaments" No NA "Cluster 17: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 45: Enterocytes - Digestion" Vesicles "Intermediate filaments" "HPA043514: AB_10959475, HPA045471: " "unprognostic (1.18e-1)" "unprognostic (3.92e-1)" "unprognostic (9.92e-2)" "unprognostic (5.56e-2)" "unprognostic (1.03e-1)" "unprognostic (6.16e-3)" "unprognostic (2.04e-1)" "unprognostic (3.22e-2)" "unprognostic (2.54e-1)" "unprognostic (8.75e-3)" "unprognostic (3.29e-1)" "unprognostic (5.16e-2)" "prognostic favorable (6.80e-10)" "unprognostic (2.63e-3)" "unprognostic (4.76e-1)" "unprognostic (3.59e-2)" "unprognostic (2.43e-1)" 0.2 0.3 0.5 3.1 0.6 0.6 6.2 1.8 0.9 4.0 6.5 23.6 31.1 1.8 7.3 4.2 4.2 4.8 0.3 1.1 0.5 12.9 5.3 2.4 0.5 0.4 0.5 0.5 17.1 12.5 1.0 5.7 0.5 6.0 18.7 2.1 11.6 2.5 0.8 3.3 33.1 0.6 0.1 0.4 2.8 0.9 0.5 0.9 3.9 0.0 1.7 3.8 2.5 0.9 21.7 0.7 0.5 0.9 0.0 0.1 30.9 0.0 0.0 0.0 0.0 23.6 22.5 0.2 2.3 0.0 0.1 21.4 1.9 10.3 0.1 0.0 12.1 0.0 0.4 6.2 0.0 0.1 0.2 0.9 12.5 0.1 0.2 0.1 0.0 0.1 0.3 0.1 0.0 40.8 0.2 0.3 3.5 13.4 0.2 0.0 0.1 8.8 0.3 18.8 3.7 0.2 0.4 18.5 0.0 2.4 26.3 0.3 0.0 0.0 0.4 0.4 0.2 0.2 0.3 0.1 0.2 0.2 0.2 1.8 0.2 0.2 0.2 0.1 0.1 0.2 0.2 0.2 0.1 0.4 0.2 0.2 1.2 0.4 0.1 0.3 0.2 0.1 0.5 0.6 1.8 0.9 1.1 0.5 0.4 0.5 0.5 0.1 0.5 0.9 0.3 9.6 8.4 0.3 0.8 7.9 28.7 9.6 22.8 7.0 25.4 10.7 0.6 40.0 17.9 9.2 0.0 36.5 1.5 150.1 1.9 29.8 4.4 14.2 1.5 1.0 61.5 0.0 0.6 33.7 2.5 1.5 6.1 19.4 0.0 3.8 0.4 9.1 3.1 0.0 0.6 68.2 14.2 1.0 1.0 3.3 0.3 1.2 0.0 0.0 0.8 1.0 0.0 0.0 0.6 26.3 102.9 0.7 0.0 38.4 199.3 27.6 17.4 19.6 0.0 4.1 1.6 9.6 5.0 19.6 3.7 4.8 1.4 0.0 61.3 44.3 MAST1 "KIAA0973, SAST" ENSG00000105613 "Microtubule associated serine/threonine kinase 1" Q9Y2H9 19 12833951-12874952 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 37.7;pituitary gland: 23.3;retina: 15.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 24.7;Cone photoreceptor cells: 43.8;Excitatory neurons: 64.7;Inhibitory neurons: 70.3;Oligodendrocyte precursor cells: 22.1;Rod photoreceptor cells: 20.4" "Cancer enhanced" "Detected in many" "glioma: 3.5" "Region enhanced" "Detected in many" "cerebral cortex: 37.7" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 9 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "AN3-CA: 23.3;SCLC-21H: 40.5;SH-SY5Y: 20.2;U-266/70: 16.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028181, HPA073106" Enhanced Supported Vesicles,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Cytosol "HPA028181: AB_10603872, HPA073106: AB_2732218" "unprognostic (6.32e-2)" "unprognostic (3.66e-2)" "unprognostic (3.93e-2)" "unprognostic (2.83e-5)" "unprognostic (1.72e-1)" "unprognostic (4.19e-2)" "unprognostic (2.38e-1)" "unprognostic (8.72e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "unprognostic (8.89e-3)" "unprognostic (3.43e-2)" "unprognostic (3.84e-3)" "unprognostic (1.19e-1)" "unprognostic (7.04e-2)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" 0.0 2.2 6.5 0.3 12.1 0.3 0.1 7.3 37.7 0.2 0.0 1.2 0.3 0.0 0.0 0.2 0.1 0.2 0.2 8.3 2.4 0.1 0.6 0.1 0.1 11.2 1.1 0.3 0.6 0.5 23.3 0.0 9.5 0.2 0.1 15.4 0.2 0.0 0.0 3.7 0.4 0.0 0.0 0.1 0.6 5.0 1.2 0.8 0.1 0.0 0.0 0.2 0.3 3.0 3.6 1.6 1.5 23.3 0.0 0.0 1.9 0.2 0.1 0.3 0.9 0.8 1.5 5.8 2.6 0.0 3.9 0.1 6.8 0.1 0.1 4.1 4.5 0.5 5.8 2.6 0.0 1.3 1.2 0.5 0.1 0.8 0.7 1.3 0.0 15.2 5.2 3.0 0.0 0.8 2.4 0.6 6.9 0.6 7.2 15.9 4.6 8.3 0.3 0.2 40.5 20.2 0.8 1.4 4.3 1.2 3.8 2.1 0.0 2.8 4.2 3.1 0.8 16.7 14.5 3.7 5.1 3.1 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 6.5 12.1 7.3 37.7 8.3 2.4 11.2 1.1 9.5 0.0 1.2 3.0 0.5 0.0 2.4 7.8 0.2 0.9 1.6 0.6 0.6 24.7 0.8 2.5 1.0 0.0 0.3 0.0 43.8 0.6 0.4 0.6 0.0 0.4 14.0 0.2 0.2 1.3 0.0 0.0 64.7 0.5 0.6 1.3 0.0 0.3 1.3 0.5 1.1 0.5 0.2 15.2 70.3 0.1 0.0 1.0 1.2 8.2 0.6 0.7 5.4 6.5 0.1 3.7 0.0 22.1 3.0 0.3 2.5 1.2 0.0 1.0 0.9 0.2 1.0 20.4 0.0 2.0 0.5 8.0 5.2 0.7 1.4 0.3 1.0 0.4 0.7 1.2 MAX "bHLHd4, bHLHd5, bHLHd6, bHLHd7, bHLHd8" ENSG00000125952 "MYC associated factor X" P61244 14 65006174-65102695 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 390.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000328, HPA003474" Supported Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "Golgi apparatus, Vesicles" "CAB000328: AB_2281783, HPA003474: AB_1079317" "unprognostic (4.50e-3)" "unprognostic (1.51e-3)" "unprognostic (4.08e-2)" "unprognostic (2.87e-1)" "unprognostic (8.37e-2)" "unprognostic (2.42e-2)" "unprognostic (1.13e-3)" "unprognostic (1.30e-3)" "unprognostic (1.53e-2)" "unprognostic (7.36e-3)" "unprognostic (7.19e-2)" "unprognostic (1.66e-2)" "prognostic unfavorable (5.57e-4)" "unprognostic (2.99e-1)" "unprognostic (4.68e-2)" "prognostic favorable (2.12e-4)" "unprognostic (6.03e-2)" 48.1 36.3 57.4 43.5 63.2 105.1 41.2 74.6 62.9 61.0 44.8 51.1 41.3 51.1 29.2 75.8 67.2 36.2 52.8 55.0 59.4 39.5 36.8 51.6 63.7 65.5 61.8 56.2 29.3 31.3 32.5 39.8 65.0 52.2 31.8 23.6 43.5 38.7 43.8 55.3 51.7 39.5 59.4 66.3 39.4 21.5 62.1 63.7 42.7 54.0 55.1 51.3 68.7 65.3 117.1 40.4 27.8 44.6 73.4 58.0 35.4 39.9 62.3 47.5 58.4 29.1 86.7 88.1 33.1 48.8 45.0 60.4 63.4 52.7 37.3 84.5 40.5 143.4 29.9 32.0 90.9 56.2 390.3 67.6 43.5 42.7 54.9 71.9 54.9 71.8 66.8 42.4 53.1 63.9 140.1 217.6 36.3 71.3 70.6 75.2 42.7 47.3 49.2 38.8 61.8 38.2 49.6 60.6 60.4 25.1 58.0 71.6 69.7 47.8 55.8 42.0 33.6 50.7 43.6 61.7 56.9 56.1 46.0 667.6 141.9 540.8 125.7 126.4 140.1 115.7 147.5 130.5 119.9 114.9 151.1 127.9 305.1 126.9 120.3 114.6 194.0 314.2 57.4 63.2 74.6 62.9 55.0 59.4 65.5 61.8 65.0 59.4 62.1 65.3 45.8 28.9 27.4 31.0 74.5 170.2 66.0 63.3 126.3 28.2 59.8 43.1 27.4 32.9 42.0 18.4 20.9 38.4 79.1 116.3 52.8 38.8 45.5 38.1 43.6 59.9 44.3 40.4 50.7 31.4 43.4 46.7 32.6 36.0 62.8 38.2 71.0 23.8 59.9 47.1 43.3 49.7 38.7 81.8 66.7 115.6 77.9 147.2 56.9 32.8 67.1 47.3 69.0 28.1 60.4 61.6 96.7 60.2 58.0 80.3 100.6 66.4 32.9 16.9 138.1 47.4 76.3 43.2 28.4 84.8 180.6 54.0 83.9 25.4 29.7 76.2 MBD1 "CXXC3, PCM1" ENSG00000141644 "Methyl-CpG binding domain protein 1" Q9UIS9 18 50266882-50281774 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 97.4;Spermatocytes: 136.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009017, CAB036003, HPA068850" Approved Enhanced Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Vesicles" "CAB009017: AB_2095559, CAB036003: , HPA068850: AB_2732121" "unprognostic (2.12e-2)" "unprognostic (5.05e-2)" "unprognostic (6.88e-2)" "unprognostic (5.01e-3)" "unprognostic (9.20e-2)" "unprognostic (6.85e-2)" "prognostic unfavorable (5.08e-6)" "unprognostic (5.91e-2)" "unprognostic (2.61e-2)" "unprognostic (4.65e-2)" "unprognostic (1.96e-3)" "prognostic unfavorable (1.70e-6)" "unprognostic (7.06e-3)" "unprognostic (7.70e-2)" "unprognostic (7.05e-2)" "unprognostic (4.61e-2)" "unprognostic (1.31e-1)" 28.5 39.8 23.9 26.2 25.9 44.2 29.1 24.8 28.2 32.3 19.3 35.7 24.8 32.1 20.5 39.2 31.6 19.6 35.7 26.7 22.2 32.5 35.7 29.9 30.2 23.1 22.0 34.8 34.5 32.4 42.8 24.6 21.1 33.0 17.7 24.0 30.5 23.5 51.0 43.4 33.7 20.4 19.5 41.0 33.6 88.1 23.1 29.6 35.4 28.6 24.2 35.3 32.2 25.6 30.9 28.6 31.5 35.9 33.2 26.9 33.9 36.2 41.4 49.2 37.7 21.6 23.9 48.5 25.8 35.3 28.8 54.4 36.3 63.4 28.4 54.7 23.2 30.6 43.8 23.1 63.9 74.8 62.1 31.5 100.4 56.2 127.2 31.1 40.9 47.4 39.3 73.8 38.3 28.5 63.3 38.9 29.8 16.1 22.7 57.8 23.3 53.2 24.4 13.8 41.5 39.5 27.0 25.5 33.2 25.4 32.4 67.4 44.7 53.0 24.1 17.3 37.2 135.8 62.2 51.6 34.3 56.8 49.0 16.0 11.2 22.7 15.3 9.7 14.6 11.6 13.5 12.9 11.2 11.4 13.8 11.4 14.5 14.3 7.8 10.2 13.8 12.6 23.9 25.9 24.8 28.2 26.7 22.2 23.1 22.0 21.1 19.5 23.1 25.6 17.7 9.6 24.6 19.6 20.1 22.7 13.9 18.2 23.3 15.1 16.5 14.5 28.1 14.3 20.5 16.5 18.8 31.1 25.0 24.5 13.7 15.7 85.1 17.1 16.1 17.6 13.1 9.7 20.4 13.8 24.2 16.5 28.1 17.3 8.8 17.7 13.9 18.1 18.7 15.2 17.3 19.5 24.4 15.8 11.1 97.4 15.5 17.5 16.0 9.4 15.7 17.4 14.4 12.1 16.4 21.1 24.5 19.2 34.6 14.4 21.3 9.7 16.9 20.3 13.1 14.8 18.9 136.0 32.5 21.6 29.3 51.4 20.0 28.1 18.6 17.0 MBNL3 "CHCR, FLJ11316, MBLX39, MBXL" ENSG00000076770 "Muscleblind like splicing regulator 3" Q9NUK0 X 132369317-132489968 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 59.3;placenta: 170.8" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 328.3;Hepatocytes: 119.6;Syncytiotrophoblasts: 344.1" "Cancer enhanced" "Detected in all" "liver cancer: 13.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CACO-2: 123.8;Hep G2: 171.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001584 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 28: Placenta - Pregnancy" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "Golgi apparatus" "HPA001584: AB_1079326" "unprognostic (3.38e-2)" "unprognostic (1.40e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (1.57e-4)" "unprognostic (1.87e-1)" "unprognostic (2.67e-3)" "unprognostic (8.74e-2)" "unprognostic (3.46e-2)" "unprognostic (2.19e-2)" "unprognostic (5.77e-3)" "unprognostic (4.36e-3)" "unprognostic (1.65e-1)" "unprognostic (1.07e-1)" "unprognostic (1.67e-1)" "unprognostic (2.43e-1)" "unprognostic (8.28e-2)" "unprognostic (2.37e-1)" 6.8 11.6 1.3 8.7 1.9 14.8 4.7 1.7 1.0 3.7 2.4 11.7 9.9 4.9 24.3 10.9 9.4 5.7 9.7 1.1 4.4 8.0 59.3 5.9 13.8 3.6 3.1 4.8 10.0 4.2 1.6 170.8 3.2 4.0 11.5 0.1 6.6 11.1 0.6 12.6 9.8 4.0 2.0 11.3 13.0 42.8 1.6 14.3 8.2 3.4 15.1 8.5 2.8 3.7 7.2 0.0 8.6 1.4 1.6 3.6 15.7 0.5 3.2 1.1 0.0 123.8 22.7 32.6 0.7 1.3 1.1 7.7 19.8 8.2 0.8 3.3 7.6 29.1 25.9 171.5 1.5 32.9 10.2 1.5 7.1 0.0 3.6 0.1 1.1 20.4 2.6 9.2 1.6 19.2 56.3 12.5 1.3 27.5 1.6 53.2 10.7 18.6 5.7 18.6 3.1 10.5 14.8 8.6 4.3 15.1 3.1 8.4 3.9 6.3 1.2 8.2 6.7 18.2 13.0 47.0 1.2 21.8 20.2 11.9 7.9 5.5 16.6 9.9 14.4 20.6 9.8 11.6 8.8 25.5 10.0 11.2 1.2 18.7 21.7 17.0 2.2 9.1 1.3 1.9 1.7 1.0 1.1 4.4 3.6 3.1 3.2 2.0 1.6 3.7 4.1 3.2 6.8 16.0 16.9 8.8 2.2 2.1 5.2 0.7 3.5 3.6 14.7 41.5 5.0 11.0 0.0 328.3 9.5 12.8 3.9 1.5 5.8 12.6 1.3 3.6 6.7 55.8 0.9 5.4 56.6 7.5 15.3 6.6 8.8 6.8 6.4 119.6 29.3 0.0 0.9 9.8 0.0 27.2 6.5 9.4 23.0 9.6 7.2 30.0 10.6 0.2 9.2 0.0 20.6 1.3 3.6 50.8 12.2 1.4 6.4 9.7 4.5 1.9 0.0 3.1 2.7 2.1 1.7 13.6 8.5 344.1 10.3 5.7 10.3 3.3 MBOAT2 "FLJ14415, FLJ90298, OACT2" ENSG00000143797 "Membrane bound O-acyltransferase domain containing 2" Q6ZWT7 2 8852690-9003709 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 171.1;Erythroid cells: 162.6;Excitatory neurons: 134.6;Horizontal cells: 141.3;Oligodendrocyte precursor cells: 177.4;Oligodendrocytes: 230.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 4.7;eosinophil: 1.7;neutrophil: 4.0" "Lineage enriched" "Detected in single" 10 "granulocytes: 4.7" "Cell line enhanced" "Detected in many" "SK-BR-3: 41.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014836 Uncertain Approved Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA014836: AB_1854745" "unprognostic (2.49e-1)" "unprognostic (2.17e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (2.13e-9)" "unprognostic (1.30e-1)" "unprognostic (2.32e-2)" "unprognostic (2.38e-1)" "unprognostic (3.97e-3)" "unprognostic (3.09e-1)" "unprognostic (3.00e-1)" "unprognostic (1.03e-3)" "unprognostic (1.70e-1)" "unprognostic (5.90e-2)" "unprognostic (2.23e-1)" "unprognostic (3.04e-2)" "unprognostic (6.66e-2)" "prognostic unfavorable (5.32e-4)" 2.2 2.1 16.4 2.4 23.6 26.9 9.0 20.5 18.4 7.7 26.2 7.6 2.4 4.6 2.7 15.8 2.9 3.6 4.6 18.9 21.9 7.0 0.8 6.7 1.9 21.8 22.2 5.8 1.4 29.3 5.4 3.2 22.4 14.4 8.5 15.6 5.7 2.3 1.1 11.6 3.7 3.9 20.6 2.4 6.1 2.1 21.9 2.4 4.5 1.1 4.8 3.8 8.4 29.3 14.0 4.2 12.7 5.4 5.6 12.5 7.3 6.5 2.4 8.5 5.6 1.1 21.9 3.9 7.5 15.9 6.8 10.5 11.4 13.5 12.6 12.3 19.0 16.7 5.9 0.0 6.9 0.0 5.0 9.1 7.8 8.1 5.6 18.5 4.5 5.5 14.4 3.0 7.5 3.6 4.9 0.3 5.0 6.4 15.8 7.4 20.0 0.1 12.6 2.0 7.6 23.0 6.9 41.1 6.6 6.2 7.7 4.8 2.5 14.7 7.7 11.6 19.0 1.1 0.4 4.3 23.3 2.4 5.1 4.7 0.4 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 4.0 0.0 0.1 0.1 0.0 0.2 16.4 23.6 20.5 18.4 18.9 21.9 21.8 22.2 22.4 20.6 21.9 29.3 7.7 19.2 12.7 171.1 1.7 3.3 4.6 33.1 0.6 20.6 18.1 12.1 12.2 7.2 54.7 40.5 8.4 3.9 1.1 28.2 5.9 5.6 9.7 3.2 19.4 13.4 37.6 162.6 134.6 1.5 1.4 12.7 21.4 2.9 8.2 14.7 4.6 0.2 1.8 141.3 107.8 59.3 32.6 1.9 17.7 12.7 5.3 5.0 14.2 33.7 29.0 98.7 0.0 177.4 230.5 88.1 42.9 7.5 0.3 19.5 1.6 10.4 45.7 8.8 6.6 10.5 15.2 12.1 24.8 24.4 5.1 1.9 2.0 1.9 12.7 66.4 MCOLN1 "ML4, MLIV, MST080, MSTP080, TRPM-L1, TRPML1" ENSG00000090674 "Mucolipin 1" Q9GZU1 19 7522624-7534009 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Calcium transport, Immunity, Ion transport, Transport" "Ion channel" "Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 109.4;Kupffer cells: 117.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 117.5;classical monocyte: 45.2;eosinophil: 105.7;intermediate monocyte: 95.5;neutrophil: 41.1;non-classical monocyte: 105.1" "Group enriched" "Detected in all" 5 "granulocytes: 117.5;monocytes: 105.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031763, CAB032637, HPA069495" Uncertain Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" Nucleoplasm "CAB032637: AB_2142964, HPA031763: AB_10600822, HPA069495: " "unprognostic (5.51e-2)" "unprognostic (1.31e-2)" "unprognostic (1.35e-2)" "unprognostic (3.30e-2)" "unprognostic (2.66e-1)" "unprognostic (4.07e-2)" "unprognostic (8.38e-3)" "unprognostic (1.57e-1)" "unprognostic (1.79e-2)" "unprognostic (1.47e-1)" "prognostic favorable (5.60e-5)" "unprognostic (1.36e-1)" "prognostic favorable (5.67e-4)" "unprognostic (2.58e-1)" "unprognostic (1.66e-1)" "unprognostic (1.07e-1)" "unprognostic (1.83e-1)" 21.2 37.4 6.4 9.2 6.5 10.4 15.3 7.0 8.4 11.7 8.3 13.6 8.3 11.6 2.7 11.0 12.2 10.1 15.7 7.0 7.4 11.7 14.7 20.3 13.2 8.2 7.4 10.0 9.9 10.2 21.7 15.9 9.0 8.7 5.6 5.0 12.3 6.1 22.2 20.8 12.1 8.1 7.1 48.2 12.8 5.6 8.2 6.2 8.5 11.7 4.1 15.8 10.9 9.9 11.6 11.7 5.6 19.1 32.0 10.3 16.1 21.2 16.9 25.2 21.6 9.0 10.0 6.5 25.5 14.5 22.2 5.3 9.5 7.3 7.4 12.7 21.1 5.8 11.0 7.3 28.0 6.6 24.5 14.5 16.8 24.1 4.2 7.9 10.7 14.2 10.9 27.9 14.7 3.9 9.1 6.6 12.6 6.1 24.8 12.6 9.4 13.8 9.6 9.9 14.4 17.8 9.1 15.8 26.8 6.1 9.6 11.4 13.5 12.0 6.9 48.8 16.0 21.5 35.5 4.7 19.2 9.2 18.4 117.5 45.2 105.7 7.7 95.5 6.3 4.2 6.5 6.3 19.2 4.1 6.0 6.5 41.1 10.3 105.1 21.1 10.0 17.1 6.4 6.5 7.0 8.4 7.0 7.4 8.2 7.4 9.0 7.1 8.2 9.9 15.1 3.2 2.6 5.9 8.0 13.4 6.5 16.9 10.2 27.3 15.9 15.0 2.3 15.7 8.1 31.3 22.9 11.6 12.1 32.0 1.9 23.7 4.8 5.0 19.8 14.1 16.8 21.7 10.6 23.1 20.0 16.0 9.7 6.5 1.3 22.2 13.6 13.6 109.4 58.9 8.0 10.0 22.4 117.1 32.2 17.0 16.4 70.6 21.4 7.5 18.0 23.0 16.5 7.5 11.4 23.4 19.3 15.8 8.0 5.6 21.8 12.3 6.5 44.1 6.6 11.2 14.8 10.3 14.7 8.9 17.3 29.6 8.7 17.3 9.4 4.8 MCUB "CCDC109B, FLJ20647" ENSG00000005059 "Mitochondrial calcium uniporter dominant negative subunit beta" Q9NWR8 4 109560209-109688719 "Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 32.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 127.7;Exocrine glandular cells: 111.4;Extravillous trophoblasts: 91.9;Hofbauer cells: 106.8;Pancreatic endocrine cells: 67.9;Syncytiotrophoblasts: 73.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 93.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA048776 Enhanced Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 30: Non-specific - Translation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Vesicles, Mitochondria" "HPA048776: AB_2680518" "unprognostic (6.12e-3)" "unprognostic (1.70e-2)" "unprognostic (3.12e-2)" "unprognostic (1.60e-1)" "unprognostic (1.42e-1)" "unprognostic (1.70e-1)" "unprognostic (1.70e-2)" "unprognostic (3.06e-1)" "unprognostic (2.35e-1)" "unprognostic (1.14e-2)" "unprognostic (1.26e-3)" "unprognostic (3.40e-1)" "prognostic unfavorable (7.35e-6)" "unprognostic (2.48e-1)" "unprognostic (5.21e-2)" "unprognostic (1.21e-1)" "unprognostic (1.42e-2)" 10.2 2.0 2.6 18.4 3.0 10.6 7.6 2.1 3.4 7.0 3.5 5.3 3.8 8.8 1.5 6.8 5.8 7.8 10.5 2.7 4.6 3.5 2.2 7.2 32.2 4.3 3.0 5.6 1.5 1.2 3.7 6.1 3.2 3.0 6.3 3.7 4.9 2.1 1.4 6.2 7.8 8.2 3.7 13.5 4.6 3.0 5.2 31.4 3.3 3.5 25.7 9.2 7.5 4.6 26.9 11.7 6.4 32.6 6.9 18.1 23.9 23.3 14.2 24.9 22.1 0.6 21.6 93.0 4.6 20.2 13.8 7.6 24.1 14.0 21.9 59.2 18.4 11.3 11.6 1.6 12.1 23.6 0.4 11.7 3.8 15.1 13.0 17.7 33.9 35.0 3.3 59.4 19.2 34.0 54.1 0.4 28.2 4.8 15.6 20.4 47.7 10.8 29.6 12.1 25.6 11.1 24.2 73.4 7.7 5.3 9.2 1.2 23.9 9.8 12.6 51.8 40.2 22.3 16.4 22.7 29.9 4.9 6.9 0.4 51.4 0.8 18.9 32.2 26.6 43.6 79.1 56.5 49.8 50.7 114.7 66.2 3.6 65.0 24.4 35.1 74.9 92.2 2.6 3.0 2.1 3.4 2.7 4.6 4.3 3.0 3.2 3.7 5.2 4.6 21.5 9.6 5.2 0.0 19.5 0.0 0.0 0.0 0.0 0.0 12.7 9.9 0.0 0.0 2.5 5.5 0.0 127.7 36.0 0.0 0.0 25.2 0.0 7.0 5.9 11.7 0.0 0.0 0.0 111.4 91.9 15.1 0.0 8.9 1.3 9.1 0.0 0.0 106.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.0 14.5 0.0 0.0 0.0 0.0 67.9 0.0 0.0 5.8 0.0 0.0 0.9 2.2 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 73.5 28.2 7.4 0.0 0.0 MDK "FLJ27379, MK, NEGF2" ENSG00000110492 Midkine P21741 11 46380756-46383837 "Cancer-related genes, Predicted secreted proteins" Differentiation "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 529.1" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 1010.4;Granulosa cells: 726.2;Paneth cells: 1272.7;Proximal enterocytes: 883.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.8;neutrophil: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NTERA-2: 888.4;REH: 1343.8;SH-SY5Y: 1093.6" "CAB010055, HPA057126" Uncertain Approved Vesicles "Secreted to blood" NA NA 158000 960000 "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 33: Fibroblasts - ECM organization" Vesicles "CAB010055: AB_627949, HPA057126: AB_2683344" "unprognostic (8.87e-3)" "unprognostic (6.65e-2)" "unprognostic (4.02e-2)" "unprognostic (7.24e-2)" "prognostic unfavorable (5.48e-4)" "unprognostic (1.90e-1)" "unprognostic (5.67e-3)" "unprognostic (1.02e-1)" "unprognostic (3.66e-2)" "unprognostic (1.11e-2)" "unprognostic (4.01e-2)" "unprognostic (4.15e-1)" "prognostic unfavorable (3.06e-6)" "unprognostic (8.78e-2)" "unprognostic (1.31e-1)" "unprognostic (3.48e-1)" "unprognostic (1.12e-2)" 41.1 98.0 23.3 22.9 23.3 11.7 82.2 27.0 37.0 379.4 16.3 78.0 263.3 208.2 60.3 38.1 170.3 140.0 36.1 21.6 40.7 35.9 8.5 48.5 20.3 31.8 27.5 529.1 30.5 103.9 370.4 32.0 22.6 128.7 38.0 5.9 137.4 84.1 7.6 26.9 211.3 49.5 24.6 78.1 108.3 16.8 31.5 92.9 26.8 9.8 15.9 84.1 129.3 24.6 51.1 66.5 758.4 2.5 5.2 62.2 18.6 39.2 77.0 145.6 128.8 505.2 219.5 3.4 528.6 58.5 6.3 429.6 431.8 0.7 13.3 157.0 91.6 22.5 5.6 703.6 336.2 1.7 3.5 100.0 13.2 89.2 0.5 31.0 214.3 28.9 385.2 3.5 83.3 348.6 19.8 9.4 888.4 275.9 388.0 1343.8 28.8 4.4 1.8 1.6 418.1 1093.6 128.9 11.3 11.0 665.8 347.3 349.5 59.0 221.1 526.2 3.1 27.2 2.9 11.0 5.1 6.5 13.7 197.3 0.0 0.0 0.0 0.1 0.2 0.0 1.8 0.1 0.2 0.0 0.4 0.0 0.0 2.1 0.1 0.2 0.1 0.9 0.4 23.3 23.3 27.0 37.0 21.6 40.7 31.8 27.5 22.6 24.6 31.5 24.6 108.2 0.0 5.4 5.5 9.6 11.1 162.1 392.4 12.5 1.3 245.2 218.7 7.0 34.3 393.6 47.8 0.0 162.3 5.4 499.0 1.9 286.0 26.4 134.6 490.2 115.0 1010.4 2.5 2.1 104.5 123.5 275.2 162.1 228.2 4.5 726.2 102.4 4.6 48.3 0.0 1.9 368.8 286.8 4.2 12.0 126.3 109.6 10.0 37.4 7.5 9.4 47.1 0.0 4.5 1.3 221.1 1272.7 18.8 18.6 163.6 883.4 19.6 109.5 1.1 85.5 26.1 197.0 31.8 34.3 26.2 8.1 153.1 11.4 8.9 187.6 511.1 MED23 "CRSP130, CRSP3, DRIP130, MRT18, Sur2" ENSG00000112282 "Mediator complex subunit 23" Q9ULK4 6 131573966-131628242 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 72.0;Inhibitory neurons: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070341 Approved Nucleoplasm,Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Vesicles" "HPA070341: AB_2686257" "unprognostic (1.11e-2)" "unprognostic (4.66e-2)" "unprognostic (5.51e-3)" "unprognostic (1.80e-1)" "unprognostic (3.06e-2)" "unprognostic (1.14e-2)" "unprognostic (6.62e-3)" "unprognostic (4.47e-1)" "unprognostic (1.64e-1)" "unprognostic (6.81e-3)" "unprognostic (1.44e-2)" "unprognostic (3.59e-1)" "unprognostic (1.64e-1)" "unprognostic (1.82e-2)" "unprognostic (2.21e-1)" "unprognostic (2.44e-2)" "unprognostic (2.53e-2)" 7.7 10.5 3.4 11.5 3.7 22.0 14.3 9.8 5.0 12.0 3.7 10.6 11.4 13.3 10.6 8.5 11.0 8.9 6.5 3.5 3.6 10.3 7.9 9.9 14.8 2.4 2.8 14.2 10.7 18.3 6.0 11.0 3.1 11.7 12.4 11.5 12.7 11.6 7.4 11.5 10.6 10.4 2.7 12.8 11.6 10.5 3.5 18.0 14.4 10.1 15.3 10.1 7.8 6.4 7.2 7.8 18.2 23.0 22.1 16.8 16.7 17.6 19.8 16.0 23.0 8.2 9.8 15.9 12.5 18.2 15.4 12.6 9.9 11.4 24.7 18.1 13.8 16.6 14.9 14.0 16.0 27.8 27.1 14.9 13.3 17.7 17.8 18.6 20.1 16.9 21.7 16.2 17.0 11.0 21.3 17.4 8.7 12.3 7.8 18.9 11.4 9.6 12.2 10.4 13.6 12.3 12.6 17.4 11.6 20.9 4.8 19.3 20.4 11.8 13.3 19.0 16.2 17.0 12.3 22.6 14.5 12.6 16.1 4.9 4.5 7.6 5.5 4.6 8.3 4.7 5.5 6.2 5.6 4.2 5.5 5.1 3.6 12.9 3.3 2.9 6.6 3.9 3.4 3.7 9.8 5.0 3.5 3.6 2.4 2.8 3.1 2.7 3.5 6.4 16.3 19.2 9.6 24.8 21.5 9.2 6.3 11.9 13.6 23.7 15.5 10.9 6.5 8.6 15.7 23.9 16.7 8.7 23.7 15.5 3.9 7.6 2.1 14.8 14.7 13.9 14.4 12.0 72.0 7.7 6.8 12.5 14.3 16.6 14.0 18.3 14.3 12.4 8.1 11.8 67.1 17.4 6.1 17.6 9.5 3.2 14.3 12.8 5.4 36.5 16.9 7.7 21.6 42.3 60.8 9.1 14.9 10.1 19.4 10.7 14.7 8.5 13.4 24.4 13.1 13.8 10.2 13.5 5.3 12.0 8.7 7.8 20.7 14.6 14.3 12.8 MED26 "CRSP7, CRSP70" ENSG00000105085 "Mediator complex subunit 26" O95402 19 16574907-16629062 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 35.9" "Cell type enhanced" "Detected in many" "Early spermatids: 65.4;Late spermatids: 67.4;Spermatocytes: 54.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057997, HPA071835" Enhanced Approved Nucleoplasm,Vesicles,Cytosol Yes No "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Vesicles, Cytosol" "HPA057997: AB_2732618, HPA071835: AB_2686455" "unprognostic (2.02e-2)" "prognostic favorable (2.46e-4)" "unprognostic (2.47e-2)" "unprognostic (2.57e-3)" "unprognostic (1.42e-1)" "unprognostic (3.60e-3)" "unprognostic (5.03e-2)" "unprognostic (3.77e-2)" "unprognostic (1.34e-2)" "unprognostic (1.17e-2)" "unprognostic (2.99e-3)" "unprognostic (2.60e-2)" "prognostic unfavorable (5.50e-5)" "unprognostic (9.43e-3)" "unprognostic (1.64e-1)" "unprognostic (5.14e-2)" "unprognostic (5.98e-3)" 4.5 3.8 4.4 3.8 4.0 11.0 4.1 5.1 4.7 4.0 4.0 4.1 2.4 4.3 1.8 5.2 3.2 2.3 3.2 5.0 5.1 2.8 3.7 4.0 4.9 5.2 4.7 4.7 3.9 3.5 3.6 3.2 4.7 4.2 1.9 2.0 4.5 2.4 6.9 6.4 3.6 2.5 3.6 4.7 3.6 35.9 4.5 4.4 3.1 3.2 4.6 3.9 4.6 4.2 11.1 4.2 3.8 8.3 4.8 3.8 11.1 6.3 4.4 6.7 6.0 6.3 6.5 17.6 6.5 4.0 2.1 8.2 5.9 6.3 4.6 13.0 12.2 6.9 4.2 5.1 4.7 7.9 6.3 4.6 6.1 5.7 5.9 4.0 3.6 9.1 11.5 20.7 4.2 11.1 8.4 7.4 9.0 5.2 13.4 8.7 5.8 19.3 4.0 4.3 10.0 5.4 5.5 5.3 6.4 2.7 3.9 10.3 4.5 8.5 6.8 10.4 8.5 14.3 12.6 14.4 6.0 10.4 5.0 0.7 0.1 0.1 0.5 0.3 0.1 0.4 0.0 0.2 0.2 0.7 0.3 0.0 0.3 0.4 0.1 1.4 0.7 0.1 4.4 4.0 5.1 4.7 5.0 5.1 5.2 4.7 4.7 3.6 4.5 4.2 13.7 3.2 12.7 11.4 11.8 14.1 5.0 3.8 11.4 4.2 14.3 12.2 1.1 2.8 3.0 5.5 10.4 6.2 15.8 5.9 3.9 4.4 65.4 12.9 7.7 6.1 2.4 5.0 8.6 4.0 11.1 7.0 5.6 16.6 1.3 5.8 4.2 5.6 5.0 5.0 7.6 4.7 2.0 8.5 10.7 67.4 6.5 9.9 1.8 1.9 4.9 6.0 4.1 7.1 8.5 6.0 3.0 3.8 15.9 6.7 3.6 2.0 3.5 6.4 0.0 17.7 8.0 54.1 19.4 11.5 10.7 16.8 11.0 6.1 5.1 8.7 MEF2C ENSG00000081189 "Myocyte enhancer factor 2C" Q06413 5 88717117-88904257 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 555.4;tongue: 246.8" "Cell type enhanced" "Detected in many" "B-cells: 471.5;Excitatory neurons: 735.7;Inhibitory neurons: 759.5;Microglial cells: 730.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "amygdala: 29.7;basal ganglia: 58.6;cerebral cortex: 75.3;hippocampal formation: 55.7" "Group enriched" "Detected in many" 4 "classical monocyte: 72.0;intermediate monocyte: 82.6;memory B-cell: 141.6;myeloid DC: 95.2;naive B-cell: 187.9;non-classical monocyte: 71.5;plasmacytoid DC: 100.3" "Group enriched" "Detected in many" 5 "B-cells: 187.9;dendritic cells: 100.3;monocytes: 82.6" "Cell line enhanced" "Detected in many" "Daudi: 103.6;HEL: 229.3;Karpas-707: 121.6;REH: 261.8;WM-115: 145.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "amygdala: 70.0;cerebral cortex: 253.1;hippocampal formation: 220.0;olfactory bulb: 66.8" "HPA005533, CAB068196, CAB068197" Enhanced Supported Nucleoplasm,Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Vesicles" "CAB068196: AB_2665646, CAB068197: AB_2665645, HPA005533: AB_1079352" "unprognostic (2.74e-1)" "unprognostic (1.64e-2)" "unprognostic (2.37e-2)" "unprognostic (8.78e-2)" "unprognostic (9.75e-2)" "unprognostic (1.69e-1)" "unprognostic (1.06e-1)" "unprognostic (3.19e-2)" "unprognostic (3.52e-2)" "unprognostic (8.73e-2)" "unprognostic (1.15e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (7.18e-3)" "unprognostic (1.58e-1)" "unprognostic (4.42e-2)" "unprognostic (1.42e-2)" 28.9 26.8 29.7 39.2 58.6 11.1 17.5 0.0 75.3 18.8 0.0 15.9 6.9 25.9 7.3 13.6 17.3 28.5 35.2 55.7 0.0 10.4 10.5 21.3 62.9 0.0 0.0 34.9 5.6 9.3 6.3 45.5 0.0 20.0 15.4 34.2 9.0 17.7 555.4 4.9 11.2 31.5 0.0 43.8 12.7 9.4 0.0 12.8 21.7 246.8 77.7 21.3 7.6 11.0 1.6 0.0 7.1 0.0 7.7 4.6 0.2 2.2 4.5 0.3 1.0 0.2 1.0 103.6 0.6 12.0 2.5 3.1 9.6 9.1 0.2 31.7 12.5 229.3 12.3 0.0 2.8 10.4 0.6 21.6 0.0 0.3 0.0 1.4 35.1 0.0 12.3 121.6 9.0 0.0 0.3 0.1 2.2 0.1 8.4 261.8 63.1 50.5 0.0 1.2 0.0 8.3 0.0 0.7 29.5 3.9 0.3 58.0 40.4 5.6 1.0 0.6 5.4 92.0 11.5 62.0 1.5 70.1 145.2 0.6 72.0 0.2 0.2 82.6 0.1 141.6 0.2 0.1 95.2 187.9 0.2 0.2 24.3 16.7 71.5 100.3 0.5 34.4 29.7 58.6 0.0 75.3 55.7 0.0 0.0 0.0 0.0 0.0 0.0 11.0 367.4 32.1 52.0 117.5 471.5 10.7 4.2 0.0 7.4 22.6 5.2 26.5 86.4 10.0 21.7 1.8 214.8 0.8 138.6 9.2 27.4 0.8 11.0 0.8 13.4 197.5 1.2 59.1 735.7 12.7 1.2 26.8 2.0 1.0 5.1 107.5 283.4 3.4 171.1 5.0 759.5 1.5 0.0 205.8 127.5 8.6 29.8 205.1 67.6 730.7 202.7 61.8 8.2 119.6 18.7 0.4 3.0 71.8 314.7 2.1 0.2 0.8 3.7 202.9 335.2 72.7 257.6 4.0 29.5 2.5 8.4 1.6 12.2 58.6 6.3 2.3 MEF2D ENSG00000116604 "Myocyte enhancer factor 2D" Q14814 1 156463727-156500779 "Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 170.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 173.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "THP-1: 211.3;U-266/70: 193.0;U-266/84: 214.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004807, HPA007114" Enhanced Enhanced Nucleoplasm,Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA004807: AB_1079354, HPA007114: AB_1079353" "unprognostic (3.17e-2)" "unprognostic (7.31e-2)" "unprognostic (3.35e-2)" "unprognostic (3.45e-2)" "unprognostic (1.95e-1)" "unprognostic (8.99e-2)" "unprognostic (2.02e-1)" "unprognostic (1.29e-1)" "unprognostic (9.96e-2)" "unprognostic (1.96e-2)" "unprognostic (1.97e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (7.53e-4)" "unprognostic (9.27e-2)" "unprognostic (1.66e-1)" "unprognostic (8.09e-3)" "unprognostic (1.45e-1)" 33.3 32.6 15.7 24.4 22.6 79.8 27.5 21.8 24.9 43.5 0.0 43.6 16.0 48.9 14.3 19.2 39.1 20.2 54.9 24.1 4.8 17.8 19.6 37.0 21.1 1.3 3.2 44.5 31.6 27.9 26.1 22.9 1.0 31.1 13.9 50.0 21.6 24.1 170.9 32.8 27.0 25.6 1.5 29.4 28.2 14.7 2.7 27.5 25.2 69.2 14.8 33.8 32.8 14.0 19.7 32.2 7.2 10.7 15.6 22.2 12.4 26.1 29.6 12.0 12.5 10.4 24.1 42.5 30.3 31.4 12.7 18.8 8.2 13.2 7.1 65.7 11.6 10.8 42.1 6.2 19.2 25.6 32.8 24.5 21.6 21.0 27.9 24.8 22.5 13.5 8.6 72.7 19.1 16.6 18.6 56.4 10.6 10.2 20.5 80.6 16.5 48.3 10.4 8.7 12.0 19.2 24.1 48.2 39.6 13.4 13.7 211.3 40.2 29.1 29.3 22.1 19.7 193.0 214.3 81.3 24.5 19.2 15.9 1.1 1.4 1.7 1.3 0.7 1.5 1.1 0.9 1.2 1.0 1.0 0.5 0.8 5.3 1.1 1.4 5.8 1.3 0.7 15.7 22.6 21.8 24.9 24.1 4.8 1.3 3.2 1.0 1.5 2.7 14.0 21.8 6.4 18.6 21.9 29.8 37.2 10.9 10.6 25.6 82.3 25.2 19.7 42.0 17.2 16.2 1.8 173.0 5.0 72.5 60.6 0.0 7.7 2.5 26.4 26.0 24.0 21.5 11.0 28.7 11.1 4.9 25.1 25.0 43.1 3.8 9.0 22.9 13.2 18.0 70.7 18.8 32.2 8.2 25.4 64.1 4.4 31.4 35.5 14.2 20.6 17.7 19.0 33.0 13.0 20.2 25.8 46.3 32.4 44.6 19.7 17.2 3.4 9.1 85.3 98.6 48.8 46.1 5.1 10.7 16.6 38.1 15.3 33.1 11.0 14.0 19.3 MEMO1 "C2orf4, CGI-27, MEMO" ENSG00000162959 "Mediator of cell motility 1" Q9Y316 2 31865060-32011230 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 115.0;Inhibitory neurons: 111.2;Microglial cells: 100.2;Oligodendrocyte precursor cells: 106.1;Oligodendrocytes: 134.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042603, HPA057952" Approved Approved Vesicles NA NA 9100 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 24: NB-4 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA042603: AB_10806243, HPA057952: AB_2683562" "unprognostic (1.33e-1)" "unprognostic (1.28e-3)" "unprognostic (1.81e-1)" "unprognostic (2.94e-5)" "unprognostic (1.02e-2)" "unprognostic (3.96e-2)" "unprognostic (2.24e-4)" "unprognostic (1.70e-2)" "unprognostic (6.73e-2)" "unprognostic (8.37e-3)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (5.95e-9)" "unprognostic (6.57e-2)" "unprognostic (2.26e-1)" "unprognostic (3.77e-2)" "unprognostic (4.23e-2)" 17.2 23.7 15.0 23.2 13.7 45.7 14.7 14.0 14.1 15.1 9.9 17.5 16.7 14.4 16.7 33.6 13.1 13.4 36.3 13.4 13.7 16.4 35.9 13.9 31.9 14.2 14.2 10.7 17.3 14.6 11.9 20.6 13.9 14.2 20.7 11.7 16.8 13.6 58.8 19.2 16.7 19.5 13.4 20.3 17.3 62.2 14.4 31.5 12.5 36.5 34.2 26.3 19.3 16.8 87.7 37.4 40.5 37.8 34.8 49.4 73.0 73.6 45.7 41.1 31.5 51.0 48.2 92.4 23.2 50.6 54.2 43.4 48.4 63.9 54.0 61.8 26.4 67.0 22.8 62.7 48.6 67.7 53.7 37.2 40.7 40.6 40.7 46.7 65.1 21.8 49.0 41.4 72.2 38.3 81.5 137.8 60.0 74.9 46.2 54.4 46.0 71.4 81.8 83.6 34.2 63.3 38.0 90.7 59.2 33.9 38.2 80.4 61.0 57.0 63.4 45.8 82.1 42.8 69.8 79.7 51.7 96.1 45.7 1.8 16.6 17.1 7.5 23.4 5.7 9.6 9.2 9.0 24.4 7.5 6.6 6.5 13.4 12.6 27.9 9.1 17.1 10.1 15.0 13.7 14.0 14.1 13.4 13.7 14.2 14.2 13.9 13.4 14.4 16.8 6.7 6.4 13.3 70.8 19.1 27.8 17.2 10.3 17.6 15.3 10.6 6.3 4.7 12.8 9.3 11.0 16.7 13.3 9.0 8.3 1.9 4.9 3.6 5.2 9.1 11.3 13.1 18.3 115.0 2.6 10.5 9.6 11.2 8.7 10.1 10.2 14.3 14.0 10.1 11.8 111.2 7.0 8.2 19.2 18.4 3.0 13.1 15.2 12.4 100.2 21.8 4.6 14.4 106.1 134.4 7.5 8.3 8.6 11.2 19.7 8.5 2.4 8.8 10.5 6.6 12.5 6.0 12.2 6.4 26.9 16.6 16.6 12.8 7.9 10.4 16.8 METAP1D "MAP1D, Metap1l" ENSG00000172878 "Methionyl aminopeptidase type 1D, mitochondrial" Q6UB28 2 171999943-172082430 "Enzymes, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 39.5;Oligodendrocyte precursor cells: 35.7;Oligodendrocytes: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030298, HPA030299, HPA077742" Uncertain Uncertain Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA030298: AB_2673419, HPA030299: AB_10602421, HPA077742: " "unprognostic (5.31e-2)" "unprognostic (1.07e-1)" "unprognostic (1.88e-1)" "unprognostic (5.83e-2)" "unprognostic (2.54e-2)" "unprognostic (7.90e-3)" "unprognostic (1.92e-3)" "unprognostic (1.07e-2)" "unprognostic (4.55e-1)" "unprognostic (7.07e-2)" "unprognostic (2.64e-2)" "unprognostic (8.19e-2)" "unprognostic (2.53e-3)" "unprognostic (3.44e-3)" "unprognostic (3.06e-2)" "unprognostic (5.48e-3)" "unprognostic (2.92e-2)" 4.4 4.9 4.3 2.4 4.5 3.5 3.9 3.7 5.0 5.4 3.7 4.6 2.3 4.5 2.8 3.4 6.7 2.0 4.8 4.1 5.1 4.5 6.0 2.3 2.8 4.1 4.1 11.9 8.1 2.2 4.3 1.8 4.6 5.6 3.2 2.5 4.1 3.7 7.8 3.4 4.1 2.8 3.6 5.8 4.6 2.8 4.3 1.2 3.6 5.6 2.0 4.2 3.8 5.0 3.6 2.8 4.1 13.5 5.9 7.7 8.3 4.1 4.1 6.4 4.1 6.4 4.7 1.8 7.2 4.3 6.6 6.4 9.1 7.2 6.5 6.3 10.6 10.2 7.8 8.6 6.2 6.1 2.6 5.8 10.9 6.4 10.2 5.5 3.6 6.9 14.8 5.1 4.9 4.4 3.5 8.2 7.4 10.4 3.4 7.7 3.5 3.3 4.5 5.0 8.4 3.2 2.9 5.8 10.2 3.6 6.7 8.1 4.4 8.1 6.4 5.0 4.0 6.3 6.1 4.0 5.8 11.9 7.9 0.0 0.0 0.0 0.4 0.4 0.2 0.3 0.5 0.2 0.1 0.7 0.5 1.1 0.0 0.4 0.0 0.0 0.4 0.2 4.3 4.5 3.7 5.0 4.1 5.1 4.1 4.1 4.6 3.6 4.3 5.0 6.1 0.0 4.6 23.8 15.4 5.6 10.3 7.5 22.8 5.8 9.2 8.9 4.5 7.2 3.5 3.7 2.1 4.1 2.7 1.3 7.9 2.5 1.2 2.7 14.7 5.4 0.0 16.8 19.6 3.5 4.7 10.9 8.2 2.5 4.5 17.9 6.4 6.4 3.9 5.0 39.5 2.9 2.0 2.5 2.2 2.3 33.5 2.2 5.4 14.0 1.0 3.7 9.2 35.7 35.5 1.4 1.3 26.4 9.9 4.3 0.6 5.7 2.0 6.1 13.1 18.1 9.5 9.8 12.2 11.6 5.7 1.9 7.5 14.5 5.7 5.1 METTL23 "C17orf95, LOC124512" ENSG00000181038 "Methyltransferase like 23" Q86XA0 17 76726830-76733936 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 182.5;Spermatocytes: 198.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022889 Approved Vesicles No No "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA022889: " "unprognostic (5.45e-3)" "unprognostic (1.22e-1)" "unprognostic (1.35e-1)" "unprognostic (1.35e-1)" "unprognostic (7.70e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (4.18e-6)" "unprognostic (5.22e-2)" "unprognostic (1.76e-1)" "unprognostic (1.73e-2)" "unprognostic (1.03e-3)" "unprognostic (3.21e-2)" "prognostic unfavorable (3.93e-7)" "unprognostic (1.13e-2)" "unprognostic (1.82e-1)" "unprognostic (3.79e-1)" "unprognostic (3.65e-1)" 30.8 32.7 20.4 24.2 22.8 27.3 30.6 22.5 27.9 28.7 24.2 26.0 22.6 25.8 34.7 23.9 27.7 19.8 28.5 20.1 21.4 39.1 47.3 26.7 42.7 21.9 22.0 29.4 42.2 35.1 33.3 19.7 22.7 28.1 27.4 22.9 29.1 21.9 34.7 29.2 30.7 23.5 22.3 48.1 30.0 51.6 21.9 36.9 42.1 25.9 40.4 26.1 24.7 26.1 68.3 58.4 32.6 30.0 79.2 66.5 31.3 33.7 68.2 43.5 41.9 29.5 47.1 38.0 32.2 43.0 56.7 37.6 23.8 61.0 48.9 19.2 55.8 49.5 38.0 56.6 77.4 35.1 41.7 64.0 57.3 54.0 74.6 68.5 69.1 46.5 48.1 46.0 53.1 38.5 44.3 30.1 24.2 75.2 65.3 29.9 54.5 106.5 63.0 33.9 30.9 44.5 33.8 51.6 123.3 78.8 72.3 43.7 25.8 49.8 24.9 48.9 59.9 63.2 26.0 38.6 47.5 25.0 46.3 23.0 28.9 34.1 48.0 30.3 53.6 51.3 53.0 53.5 32.1 44.7 50.2 51.1 9.4 51.8 27.9 48.3 57.6 34.5 20.4 22.8 22.5 27.9 20.1 21.4 21.9 22.0 22.7 22.3 21.9 26.1 39.5 28.9 14.5 8.5 49.6 16.4 47.2 64.8 42.1 13.9 34.9 48.4 17.7 27.1 35.6 20.2 10.4 42.9 50.7 11.7 119.3 42.0 182.5 31.7 23.4 28.0 22.8 22.3 4.2 39.5 41.1 26.6 24.5 25.9 31.1 21.8 25.7 49.9 57.0 6.7 5.4 24.5 40.7 33.3 23.5 54.5 32.6 33.9 24.9 8.4 50.1 38.6 81.4 7.5 13.4 33.2 26.3 25.9 49.2 33.2 27.5 87.8 32.7 23.7 52.6 28.1 43.0 198.9 49.5 32.2 16.2 17.2 55.3 53.3 32.1 34.1 METTL6 MGC24132 ENSG00000206562 "Methyltransferase like 6" Q8TCB7 3 15381275-15440566 "Metabolic proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 223.0;Late spermatids: 121.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035166 Uncertain Approved Vesicles No No "Cluster 40: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA035166: AB_10602709" "unprognostic (2.73e-1)" "unprognostic (3.53e-1)" "unprognostic (2.60e-1)" "unprognostic (1.29e-2)" "unprognostic (6.60e-2)" "unprognostic (2.20e-1)" "prognostic unfavorable (2.66e-6)" "unprognostic (3.98e-1)" "unprognostic (1.82e-1)" "unprognostic (1.13e-1)" "unprognostic (1.45e-1)" "unprognostic (2.19e-2)" "unprognostic (1.68e-2)" "unprognostic (1.27e-2)" "unprognostic (2.81e-1)" "unprognostic (3.77e-2)" "unprognostic (2.46e-1)" 7.9 7.0 13.7 7.5 13.8 5.3 9.7 13.9 15.9 9.0 6.5 6.1 6.2 8.9 8.8 8.2 9.5 6.2 7.8 14.4 13.3 6.9 6.3 6.7 9.2 11.0 10.9 12.2 6.5 9.2 8.3 9.2 11.4 8.5 7.1 13.2 5.7 9.1 7.0 8.1 5.8 10.3 11.6 7.5 7.0 18.0 14.0 10.2 9.5 7.7 10.0 7.6 6.5 16.8 13.5 21.4 23.4 20.2 21.0 23.7 59.3 24.0 24.5 28.4 29.9 12.9 17.2 22.3 16.1 22.7 24.2 11.0 23.3 20.8 30.0 15.9 25.6 21.4 20.6 19.9 39.7 20.5 18.5 21.3 25.6 34.1 17.1 22.9 26.6 22.8 22.5 22.4 28.6 28.0 22.7 17.0 23.7 14.2 25.6 17.4 29.0 22.0 17.1 18.6 10.1 18.7 20.9 19.1 19.8 16.9 27.9 17.6 18.1 22.0 14.1 22.3 22.0 24.1 43.9 26.7 23.6 19.5 21.1 7.2 8.1 12.2 9.7 10.7 9.6 7.6 9.1 9.7 9.2 9.6 9.1 10.0 4.7 11.8 10.5 12.4 9.1 6.9 13.7 13.8 13.9 15.9 14.4 13.3 11.0 10.9 11.4 11.6 14.0 16.8 5.6 3.2 5.5 20.5 6.8 4.0 8.0 13.9 10.2 17.4 5.9 6.5 5.5 1.5 7.8 9.2 6.2 9.2 5.0 1.3 5.9 10.2 223.0 5.9 10.7 7.7 1.8 6.3 37.4 13.5 21.5 8.2 4.1 5.4 5.1 14.2 5.3 2.3 9.0 20.2 38.2 2.3 4.1 4.4 4.2 121.3 9.0 6.8 5.4 9.4 8.0 11.9 13.4 17.1 22.0 9.2 2.7 9.1 10.3 5.5 4.6 4.9 9.3 15.9 6.6 8.7 8.6 31.3 17.6 6.3 2.8 11.6 8.2 11.4 3.7 5.3 METTL7B "ALDI, MGC17301" ENSG00000170439 "Methyltransferase like 7B" Q6UX53 12 55681678-55684611 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 133.1;heart muscle: 124.2;liver: 284.3" "Cell type enhanced" "Detected in some" "Hepatocytes: 83.9;Hofbauer cells: 72.7;Proximal enterocytes: 192.4;Proximal tubular cells: 55.6" "Cancer enhanced" "Detected in many" "glioma: 97.9;liver cancer: 97.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "intermediate monocyte: 4.5;myeloid DC: 7.0;naive B-cell: 1.7;non-classical monocyte: 3.3" "Group enriched" "Detected in many" 45 "B-cells: 1.7;dendritic cells: 7.0;monocytes: 4.5" "Cell line enhanced" "Detected in many" "CACO-2: 28.4;CAPAN-2: 56.6;EFO-21: 41.3;Hep G2: 28.7;LHCN-M2: 47.0;OE19: 32.5;THP-1: 42.2;U-87 MG: 41.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA038644 Enhanced Approved Vesicles,Microtubules NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" Microtubules Vesicles "HPA038644: AB_2676130" "unprognostic (7.54e-2)" "unprognostic (7.15e-2)" "unprognostic (5.55e-2)" "unprognostic (3.07e-3)" "unprognostic (6.30e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (2.00e-1)" "unprognostic (2.22e-1)" "unprognostic (1.22e-1)" "unprognostic (2.55e-1)" "unprognostic (2.98e-2)" "unprognostic (5.33e-2)" "unprognostic (2.64e-1)" "unprognostic (2.76e-2)" "unprognostic (7.10e-2)" "prognostic favorable (2.37e-4)" "unprognostic (2.43e-1)" 2.1 1.7 5.5 1.8 5.9 1.2 0.9 4.9 10.8 0.4 5.9 28.5 59.6 0.4 133.1 0.1 3.1 11.7 124.2 13.1 5.9 52.1 284.3 1.6 2.3 8.4 5.5 0.1 2.9 0.2 3.1 10.9 5.0 0.3 23.6 1.3 0.5 0.8 7.4 0.9 55.3 2.1 5.7 4.3 4.2 0.7 11.6 0.2 3.3 10.0 0.5 1.3 0.1 7.7 0.4 21.8 0.1 0.5 4.3 15.3 0.3 0.8 3.2 0.2 1.4 28.4 56.6 11.6 41.3 1.2 1.1 0.1 4.1 0.3 0.8 0.0 5.4 1.2 3.2 28.7 0.0 0.6 0.0 4.0 0.0 1.0 0.0 4.2 0.0 0.0 0.2 0.0 47.0 20.2 0.0 0.4 5.7 32.5 2.7 0.0 1.5 2.7 0.5 0.1 0.1 0.3 2.2 0.0 3.9 0.2 3.8 42.2 0.0 3.1 3.5 0.4 2.9 0.0 0.6 3.5 41.9 9.9 0.2 0.0 0.8 0.0 0.0 4.5 0.0 0.5 0.0 0.0 7.0 1.7 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.4 5.5 5.9 4.9 10.8 13.1 5.9 8.4 5.5 5.0 5.7 11.6 7.7 0.0 0.0 1.5 0.7 0.5 0.0 0.3 0.0 0.0 0.0 0.1 0.1 26.5 22.8 0.6 0.0 0.0 0.5 0.0 29.0 3.9 3.9 0.0 0.1 0.0 0.5 1.2 4.0 0.7 5.1 0.5 2.0 2.6 0.2 0.0 0.8 1.1 83.9 72.7 0.0 0.1 14.0 0.0 17.0 0.0 0.0 0.0 3.3 0.0 0.0 0.2 0.5 0.0 0.0 0.0 4.6 20.7 1.2 0.0 0.1 192.4 55.6 0.0 0.0 0.0 7.8 0.6 0.0 0.1 0.0 0.0 0.7 0.3 0.1 22.2 0.1 MEX3C "FLJ38871, RKHD2, RNF194" ENSG00000176624 "Mex-3 RNA binding family member C" Q5U5Q3 18 51174550-51218333 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 118.4" "Group enriched" "Detected in many" 6 "Early spermatids: 555.3;Late spermatids: 514.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040603 Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA040603: AB_10805714" "unprognostic (1.09e-1)" "unprognostic (2.90e-2)" "unprognostic (8.88e-2)" "unprognostic (8.88e-3)" "unprognostic (2.04e-1)" "unprognostic (7.30e-2)" "prognostic unfavorable (8.49e-5)" "unprognostic (4.34e-2)" "unprognostic (4.43e-1)" "unprognostic (1.05e-2)" "unprognostic (1.03e-2)" "unprognostic (6.75e-2)" "unprognostic (7.99e-2)" "unprognostic (1.82e-1)" "unprognostic (1.48e-1)" "unprognostic (8.01e-2)" "unprognostic (3.17e-1)" 17.6 13.5 9.1 17.0 9.9 49.4 17.4 12.5 12.3 16.4 9.0 13.5 12.6 17.6 10.4 15.5 14.0 18.6 10.8 10.5 9.8 11.9 14.0 13.7 23.6 10.5 10.0 23.5 14.7 17.9 1.7 16.1 10.6 11.5 14.1 14.8 9.6 12.2 9.7 9.2 13.4 20.1 10.7 22.3 13.3 118.4 9.3 40.9 16.1 17.1 26.6 20.2 2.4 11.6 23.8 19.6 71.2 26.8 27.7 36.8 49.6 32.8 37.4 18.9 22.2 33.6 17.3 53.0 13.2 44.2 30.4 44.6 27.9 42.7 31.0 43.0 12.5 10.7 19.1 29.0 44.5 75.2 22.3 28.2 46.5 26.9 76.4 47.0 41.8 36.0 11.3 95.7 40.0 18.0 63.8 24.3 32.1 13.3 15.0 61.7 36.5 46.7 31.1 9.5 34.8 39.1 30.4 12.4 117.7 54.3 13.5 34.3 43.2 46.3 30.9 15.1 28.1 64.5 12.4 87.2 32.9 31.3 110.7 9.7 1.2 1.5 2.3 1.0 2.0 1.9 2.4 2.4 1.4 1.1 0.9 2.3 0.4 3.4 0.7 1.1 2.0 1.4 9.1 9.9 12.5 12.3 10.5 9.8 10.5 10.0 10.6 10.7 9.3 11.6 25.2 19.2 5.0 6.8 18.6 38.2 10.3 12.4 11.4 12.6 25.9 23.2 14.5 14.3 11.2 3.7 20.9 5.2 56.6 9.0 5.9 12.1 555.3 18.9 22.7 30.0 6.7 7.4 8.0 8.5 7.0 18.2 6.1 34.9 12.7 79.3 10.4 7.6 7.7 11.8 7.9 9.4 12.2 10.9 20.5 514.0 16.1 13.8 19.6 5.6 8.2 10.0 34.0 14.1 13.3 16.5 3.9 15.1 20.6 15.4 9.1 9.3 6.4 14.8 0.0 30.2 17.7 14.4 14.2 18.1 45.9 4.2 24.2 14.9 11.5 19.6 MFNG ENSG00000100060 "MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" O00587 22 37469063-37486393 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 69.1" "Cell type enhanced" "Detected in many" "Adipocytes: 51.4;dendritic cells: 54.6;Endothelial cells: 37.1;Hepatic stellate cells: 53.2;Kupffer cells: 45.8;monocytes: 40.6;NK-cells: 72.1;T-cells: 51.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 174.6;HEL: 143.4;HL-60: 220.9;HMC-1: 266.9;HUVEC TERT2: 232.9;TIME: 134.7;U-698: 166.8;U-937: 201.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA048936, HPA056479" Approved Approved Vesicles "Intracellular and membrane" NA NA 74000 "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA048936: AB_2680564, HPA056479: " "unprognostic (1.21e-1)" "unprognostic (4.17e-3)" "prognostic unfavorable (5.12e-4)" "prognostic favorable (1.65e-4)" "unprognostic (6.41e-3)" "unprognostic (1.00e-2)" "unprognostic (2.64e-1)" "unprognostic (2.36e-2)" "unprognostic (4.64e-2)" "unprognostic (2.91e-2)" "unprognostic (5.44e-2)" "unprognostic (1.42e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (2.67e-1)" "unprognostic (4.03e-2)" "unprognostic (3.86e-2)" "unprognostic (1.43e-1)" 22.2 7.1 8.9 37.0 8.9 40.3 14.8 8.4 10.8 8.9 6.4 10.5 8.6 9.7 2.4 7.5 11.0 14.5 14.6 7.9 9.2 9.5 7.1 26.3 69.1 18.1 10.8 3.1 3.9 2.6 3.1 30.3 20.5 6.6 7.8 0.7 5.4 5.7 7.5 5.0 24.0 11.5 10.2 58.9 8.6 2.9 11.0 50.5 9.6 8.8 42.5 13.9 6.2 10.3 6.0 2.2 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.2 7.1 3.0 174.6 0.7 0.0 0.8 10.8 45.1 8.7 0.2 81.6 1.0 143.4 0.6 1.5 0.6 220.9 266.9 0.0 2.6 1.7 3.2 0.9 232.9 69.0 0.7 73.8 0.0 1.5 27.8 3.0 0.4 6.1 1.0 67.0 1.8 128.7 0.4 0.1 94.1 0.9 0.5 0.3 0.3 0.8 1.3 14.1 134.7 0.0 5.8 22.8 0.6 0.4 0.4 166.8 1.1 201.1 2.7 210.3 198.9 386.5 196.1 196.1 214.5 103.0 222.7 206.1 204.1 113.5 243.4 209.9 127.9 217.1 218.7 51.7 284.3 314.0 8.9 8.9 8.4 10.8 7.9 9.2 18.1 10.8 20.5 10.2 11.0 10.3 51.4 0.0 3.8 0.0 35.4 3.7 0.4 0.2 0.0 6.3 1.0 1.3 1.6 5.7 3.1 0.0 0.0 0.3 54.6 1.1 0.0 2.9 0.2 0.4 0.2 37.1 1.2 30.1 0.1 0.9 0.3 1.1 2.0 1.0 31.6 0.1 53.2 1.5 31.9 0.0 0.1 2.1 0.0 45.8 20.2 0.3 0.0 33.5 3.6 6.5 40.6 0.1 72.1 0.0 0.0 3.7 4.0 0.0 35.0 0.5 2.3 0.3 0.1 0.6 0.0 1.6 1.0 0.1 0.7 0.3 2.4 0.7 51.0 0.1 0.8 0.4 MFSD14A "DKFZP564L0864, HIAT1" ENSG00000156875 "Major facilitator superfamily domain containing 14A" Q96MC6 1 100038095-100083377 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 131.4" "Group enriched" "Detected in many" 5 "Early spermatids: 303.1;Late spermatids: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA073127, HPA073681" Approved Approved Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA073127: , HPA073681: AB_2686625" "unprognostic (1.37e-1)" "unprognostic (3.49e-2)" "unprognostic (2.51e-3)" "unprognostic (1.54e-1)" "unprognostic (2.18e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.08e-4)" "unprognostic (2.16e-1)" "unprognostic (7.75e-2)" "unprognostic (2.39e-1)" "unprognostic (1.11e-2)" "unprognostic (1.14e-1)" "unprognostic (1.18e-1)" "unprognostic (2.41e-1)" "unprognostic (3.84e-1)" "unprognostic (1.05e-1)" "unprognostic (5.15e-2)" 29.1 28.5 18.1 26.2 21.1 90.3 27.4 21.2 24.7 25.9 20.8 26.8 19.6 35.3 26.0 29.0 26.6 25.2 19.6 18.2 21.1 29.7 29.5 28.8 28.4 23.3 20.2 30.5 31.5 131.4 18.7 34.1 22.1 33.4 21.8 19.6 23.0 31.4 15.0 24.9 19.6 35.5 21.9 28.4 22.4 35.3 20.0 31.1 27.9 20.1 29.2 33.5 24.0 25.7 54.3 22.2 48.9 25.4 56.0 52.8 41.3 38.9 65.9 51.5 59.9 18.9 37.0 40.5 61.7 50.6 34.1 51.0 44.0 42.8 49.2 35.6 34.8 40.1 32.8 28.6 49.4 65.0 50.2 43.3 64.1 45.5 57.9 45.3 40.2 45.1 49.8 77.2 48.1 16.0 49.3 38.1 56.4 26.2 32.4 34.1 59.6 39.8 54.8 46.9 50.7 45.2 43.8 63.0 66.6 30.9 24.6 65.3 44.5 42.3 29.6 44.9 40.9 72.8 82.4 56.0 46.1 46.6 18.6 80.1 56.0 54.6 49.5 51.4 55.9 46.2 49.6 54.4 55.2 38.8 54.8 51.5 94.8 59.9 45.2 25.6 60.3 72.0 18.1 21.1 21.2 24.7 18.2 21.1 23.3 20.2 22.1 21.9 20.0 25.7 4.5 6.4 11.5 0.0 33.5 0.0 47.5 0.0 43.3 17.8 3.4 1.5 0.0 27.1 3.7 3.7 10.4 37.5 7.8 6.5 1.9 10.1 303.1 1.0 1.7 20.8 13.3 35.8 0.0 7.2 33.5 19.5 18.3 1.5 2.5 0.6 19.6 17.1 23.1 13.5 0.0 9.4 0.0 26.4 0.0 373.8 22.7 15.8 0.0 0.0 22.2 25.1 33.0 0.0 0.0 6.5 17.1 30.5 41.9 56.3 8.1 1.1 5.8 11.6 13.1 25.6 12.8 28.2 22.5 43.4 0.0 58.3 33.7 0.4 9.6 52.3 MFSD3 ENSG00000167700 "Major facilitator superfamily domain containing 3" Q96ES6 8 144509070-144511213 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 53.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056013 Uncertain Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA056013: AB_2683009" "unprognostic (7.92e-2)" "prognostic unfavorable (5.08e-4)" "unprognostic (2.00e-1)" "unprognostic (5.18e-2)" "unprognostic (6.50e-2)" "unprognostic (3.74e-2)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" "unprognostic (9.41e-2)" "unprognostic (1.06e-1)" "unprognostic (5.49e-2)" "unprognostic (5.29e-2)" "prognostic favorable (5.44e-7)" "unprognostic (4.08e-3)" "unprognostic (2.37e-1)" "unprognostic (1.50e-1)" "unprognostic (9.81e-2)" 8.4 22.6 9.2 3.4 8.0 1.8 10.7 7.2 12.0 8.0 6.4 22.6 13.5 8.3 4.1 16.1 8.4 2.5 21.8 8.8 6.7 27.5 44.6 7.6 2.8 10.8 7.1 6.7 18.8 12.3 17.8 1.5 9.4 19.2 3.3 1.5 19.6 5.4 23.5 17.8 15.4 1.2 5.4 10.8 15.6 6.3 9.5 2.3 23.9 6.1 1.7 9.7 9.2 7.0 16.2 21.7 5.4 4.6 5.9 4.4 17.6 5.1 5.3 2.8 4.2 7.3 11.2 23.3 17.3 4.8 5.6 15.5 2.5 12.1 0.5 11.0 44.0 7.5 19.9 18.3 11.0 3.6 9.9 6.5 22.3 1.8 7.7 12.1 7.3 16.0 14.2 6.2 6.8 53.7 9.0 18.9 14.3 22.9 36.9 9.9 2.8 41.7 13.2 9.5 39.1 19.7 13.0 31.6 11.3 3.4 33.1 5.2 7.9 3.7 9.9 4.2 7.1 6.0 2.6 8.1 8.0 11.3 6.5 1.8 7.4 3.8 3.9 6.7 3.7 4.9 3.9 4.0 11.0 2.5 3.5 3.6 0.4 3.8 3.6 19.2 4.4 4.1 9.2 8.0 7.2 12.0 8.8 6.7 10.8 7.1 9.4 5.4 9.5 7.0 3.0 3.2 3.7 6.5 8.0 6.0 10.3 17.3 8.6 8.2 18.8 14.5 9.3 30.0 11.8 27.6 10.4 16.5 3.7 31.3 37.2 17.6 0.6 5.1 3.9 3.8 19.8 8.2 6.2 21.0 15.0 4.0 16.3 7.4 0.0 9.7 3.3 27.6 15.5 16.8 6.2 19.6 24.4 7.0 3.2 1.8 4.4 6.4 8.8 1.9 7.5 14.8 6.2 2.5 3.8 15.7 19.1 4.9 14.8 12.8 33.1 63.6 3.2 10.0 0.0 7.0 3.4 3.8 11.7 19.0 7.1 9.3 3.5 16.9 27.1 9.8 MFSD8 "CLN7, MGC33302" ENSG00000164073 "Major facilitator superfamily domain containing 8" Q8NHS3 4 127917799-127966034 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044802 Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" Vesicles Nucleoplasm "HPA044802: AB_10963221" "unprognostic (1.67e-1)" "unprognostic (1.95e-1)" "unprognostic (4.47e-2)" "unprognostic (8.10e-2)" "unprognostic (1.57e-1)" "unprognostic (4.12e-2)" "unprognostic (1.18e-1)" "unprognostic (8.99e-2)" "unprognostic (2.19e-2)" "unprognostic (8.69e-2)" "unprognostic (4.51e-2)" "unprognostic (3.44e-2)" "unprognostic (3.93e-3)" "unprognostic (1.70e-1)" "unprognostic (5.61e-3)" "unprognostic (3.14e-1)" "prognostic favorable (2.21e-4)" 4.6 5.7 1.3 6.8 1.3 2.6 6.9 1.9 1.6 6.2 1.1 6.8 10.0 5.6 3.9 5.4 5.5 4.8 3.8 1.1 1.7 6.4 10.0 4.8 5.4 1.4 1.3 6.8 8.1 9.1 7.1 5.9 1.5 5.5 8.2 4.6 5.8 4.4 3.7 5.9 7.6 5.8 1.1 7.3 6.4 3.9 0.8 5.2 7.0 4.4 7.9 5.3 5.9 2.2 10.9 7.3 9.5 4.6 7.2 6.9 7.0 8.3 10.3 10.2 10.5 5.2 14.3 5.2 14.5 14.3 14.8 7.8 10.2 7.4 14.4 10.8 7.9 5.7 9.1 8.0 9.4 6.0 6.6 8.3 2.7 8.6 7.7 5.0 10.6 6.6 9.5 5.9 14.6 8.9 5.0 1.9 1.7 11.8 5.2 5.3 0.6 4.7 7.5 13.9 8.5 2.9 9.0 12.0 3.5 6.4 5.6 5.1 6.7 2.9 3.1 10.7 7.8 12.5 22.1 9.6 10.3 5.3 8.8 1.9 1.6 2.8 2.5 2.4 2.4 2.5 2.7 2.2 1.6 1.1 2.4 2.6 2.5 2.4 3.7 2.2 3.4 1.2 1.3 1.3 1.9 1.6 1.1 1.7 1.4 1.3 1.5 1.1 0.8 2.2 9.5 12.8 14.1 17.0 18.8 3.2 4.9 8.5 10.2 17.2 8.1 5.3 3.0 5.7 14.0 16.5 20.9 12.5 17.9 7.2 1.9 8.5 10.4 7.7 7.2 7.2 4.2 3.8 32.1 7.0 7.3 8.6 11.7 8.2 12.7 18.4 8.9 10.1 7.6 11.8 34.9 6.8 10.2 8.5 3.3 14.7 9.3 6.5 3.6 27.2 10.5 8.6 20.6 20.6 24.6 7.8 9.5 9.4 19.9 5.4 11.1 6.3 12.1 24.9 6.6 5.8 6.6 12.6 8.4 8.9 5.7 22.0 13.7 11.4 7.3 4.8 MGAM2 ENSG00000257743 "Maltase-glucoamylase 2 (putative)" Q2M2H8 7 142111749-142222324 "Enzymes, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 11.8;pancreas: 4.0;salivary gland: 5.9" "Group enriched" "Detected in some" 4 "Early spermatids: 27.4;Late spermatids: 18.2" "Group enriched" "Detected in some" 11 "colorectal cancer: 3.5;pancreatic cancer: 2.5;stomach cancer: 9.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "OE19: 1.6;RH-30: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA055697 Enhanced Approved Vesicles,Cytosol NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" Vesicles Cytosol "HPA055697: AB_2682890" "unprognostic (1.79e-2)" "unprognostic (1.00e-1)" "unprognostic (1.26e-1)" "unprognostic (5.27e-3)" "unprognostic (5.65e-2)" "unprognostic (2.19e-2)" "unprognostic (1.89e-2)" "unprognostic (1.01e-1)" "unprognostic (1.50e-2)" "unprognostic (5.93e-2)" "unprognostic (2.43e-1)" "unprognostic (2.05e-1)" "unprognostic (5.50e-4)" "unprognostic (7.11e-3)" "unprognostic (1.66e-1)" "unprognostic (6.71e-2)" "unprognostic (9.33e-2)" 0.1 0.0 0.0 0.4 0.0 0.2 1.1 0.0 0.4 0.0 0.2 1.5 11.8 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 5.9 0.0 0.0 0.0 9.6 0.0 0.0 0.9 0.5 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.5 27.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 MGAT4B GnT-Ivb ENSG00000161013 "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B" Q9UQ53 5 179797597-179806952 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 277.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 224.7;Proximal enterocytes: 224.5;Undifferentiated cells: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 5.5" "Lineage enriched" "Detected in single" 6 "granulocytes: 5.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012804, HPA052134" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" "Intracellular and membrane" NA NA 19000 "Cluster 52: Eosinophils - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Golgi apparatus, Vesicles, Cytosol" "HPA012804: , HPA052134: AB_2681741" "unprognostic (2.01e-2)" "unprognostic (8.68e-3)" "unprognostic (1.40e-1)" "unprognostic (3.83e-2)" "prognostic unfavorable (6.15e-5)" "unprognostic (3.61e-3)" "unprognostic (7.57e-3)" "unprognostic (1.22e-2)" "unprognostic (2.02e-1)" "unprognostic (5.13e-2)" "unprognostic (2.26e-2)" "unprognostic (2.27e-2)" "prognostic favorable (5.78e-4)" "unprognostic (1.52e-1)" "unprognostic (2.54e-1)" "unprognostic (1.72e-2)" "unprognostic (1.42e-1)" 48.4 105.0 17.2 19.0 16.9 24.6 39.9 16.8 19.3 37.0 18.1 147.0 134.1 36.9 13.4 75.1 37.2 23.5 103.3 18.9 14.2 124.8 277.1 61.2 15.5 16.3 15.0 41.1 63.3 22.9 37.7 17.9 15.1 42.3 65.0 4.4 57.9 11.9 43.8 53.4 168.3 14.9 14.6 52.8 96.3 30.6 18.0 10.5 60.1 14.9 16.0 38.7 42.1 16.2 84.2 85.3 40.8 93.7 117.4 65.1 71.1 48.3 98.3 44.4 34.8 91.7 226.4 14.4 122.3 108.2 193.1 61.6 57.9 110.1 32.2 121.0 33.0 43.5 75.1 78.4 85.9 53.7 13.4 70.5 76.6 44.1 53.0 165.2 89.1 16.9 28.7 38.5 73.6 92.6 8.4 47.4 24.7 123.7 35.1 21.6 31.4 40.4 132.3 158.5 67.5 39.7 73.7 75.2 139.1 33.8 51.3 56.3 109.2 106.6 48.6 61.2 80.2 32.5 39.5 35.4 125.0 68.2 78.7 0.0 0.4 5.5 0.1 0.1 0.0 0.0 0.3 0.1 0.3 0.9 0.2 0.3 0.1 0.0 0.3 0.3 0.0 0.2 17.2 16.9 16.8 19.3 18.9 14.2 16.3 15.0 15.1 14.6 18.0 16.2 35.7 12.8 9.2 9.4 7.7 12.5 17.8 12.5 5.2 15.5 29.6 30.7 24.1 37.1 11.1 27.6 4.2 8.1 22.1 224.7 3.9 66.7 0.7 27.2 17.8 24.3 22.9 5.5 11.4 54.0 11.1 15.3 78.5 50.5 5.1 39.5 26.7 89.9 17.7 30.3 10.0 72.2 14.2 20.7 11.7 2.6 15.2 24.5 10.6 9.4 16.8 25.7 6.2 4.5 6.3 89.9 114.6 17.0 7.0 49.0 224.5 22.4 7.7 11.1 13.1 16.2 24.7 1.5 6.5 21.1 11.9 14.0 12.5 24.9 131.8 64.8 MGAT4C HGNT-IV-H ENSG00000182050 "MGAT4 family member C" Q9UBM8 12 85955666-86838904 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "epididymis: 3.7;pituitary gland: 3.1;testis: 4.7;thyroid gland: 6.2" "Group enriched" "Detected in some" 8 "Astrocytes: 876.3;Excitatory neurons: 988.4;Inhibitory neurons: 1438.9" "Cancer enriched" "Detected in single" 19 "thyroid cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "NTERA-2: 6.0;SCLC-21H: 2.5;SuSa: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016418 Approved Approved "Vesicles,Plasma membrane,Centriolar satellite" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane" "Centriolar satellite" "HPA016418: AB_2732416" "unprognostic (5.23e-2)" "unprognostic (2.33e-1)" "unprognostic (1.84e-1)" "unprognostic (3.32e-4)" "unprognostic (1.07e-1)" "unprognostic (9.64e-2)" "unprognostic (5.94e-3)" "unprognostic (1.88e-1)" "unprognostic (8.05e-2)" "unprognostic (1.89e-1)" "unprognostic (6.32e-3)" "unprognostic (3.51e-2)" "unprognostic (6.85e-10)" "unprognostic (3.15e-2)" "unprognostic (1.77e-1)" "unprognostic (1.97e-1)" "unprognostic (4.74e-3)" 0.3 0.8 1.7 0.0 2.0 0.1 0.0 0.2 1.4 0.1 0.0 0.4 0.0 0.0 3.7 0.0 0.1 0.1 1.7 1.0 1.8 0.0 0.1 0.1 0.0 1.0 2.4 0.0 0.1 0.0 3.1 0.0 1.6 0.2 0.1 0.5 0.0 0.6 0.0 0.0 0.1 0.0 1.1 0.0 0.1 4.7 2.3 0.0 6.2 0.0 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.0 0.2 1.4 1.0 1.8 1.0 2.4 1.6 1.1 2.3 0.7 0.1 6.4 1.1 876.3 0.0 0.1 0.2 1.5 0.0 11.2 0.0 0.0 10.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 123.9 0.1 0.1 4.2 0.0 0.0 988.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1438.9 0.0 4.1 0.0 0.0 98.9 16.1 0.3 0.0 34.7 0.2 0.5 0.0 32.2 17.2 0.4 0.0 4.1 0.0 0.3 0.0 0.1 0.0 1.8 0.0 0.4 0.2 3.8 1.5 0.0 0.1 0.0 0.5 6.2 0.0 0.3 MGRN1 "KIAA0544, RNF156" ENSG00000102858 "Mahogunin ring finger 1" O60291 16 4616493-4690974 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 16.2" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007653, HPA008033" Approved Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 18: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 52: Non-specific - Transcription" Vesicles "Endoplasmic reticulum" "HPA007653: AB_1846304, HPA008033: " "unprognostic (2.27e-1)" "unprognostic (1.09e-1)" "unprognostic (1.18e-1)" "unprognostic (1.04e-2)" "unprognostic (1.06e-1)" "unprognostic (1.97e-2)" "unprognostic (4.24e-1)" "unprognostic (1.26e-2)" "unprognostic (9.96e-2)" "unprognostic (1.70e-1)" "unprognostic (4.03e-2)" "unprognostic (9.47e-2)" "unprognostic (6.41e-2)" "unprognostic (2.32e-1)" "unprognostic (9.06e-2)" "unprognostic (1.79e-1)" "unprognostic (5.04e-2)" 23.3 34.3 18.6 25.0 20.6 32.6 22.8 11.9 25.4 28.3 4.9 30.6 28.9 36.9 6.8 20.4 32.1 19.7 26.9 26.4 11.4 24.0 53.5 30.3 18.1 14.1 10.4 30.5 34.6 18.5 33.2 18.5 8.8 30.1 10.9 9.0 25.6 20.5 52.1 23.0 29.9 17.5 8.1 37.7 35.3 18.0 12.0 11.7 28.8 16.7 10.9 28.2 20.6 24.3 13.6 63.9 32.4 33.2 19.0 18.4 44.0 28.7 20.0 23.6 20.0 42.5 31.4 40.0 36.2 35.0 17.6 21.4 26.0 23.6 7.0 56.0 28.8 22.0 45.2 59.6 34.7 32.1 52.3 34.2 15.0 33.0 14.1 17.0 23.0 26.0 32.7 28.6 16.4 59.7 33.3 42.9 48.0 19.2 27.4 60.7 17.0 54.3 20.8 39.3 51.8 42.8 47.6 50.6 28.2 14.8 30.7 31.4 40.8 43.7 24.1 124.3 25.0 44.6 37.8 27.2 18.6 31.8 32.0 5.4 3.5 3.8 2.5 3.9 2.3 1.3 1.4 2.3 2.4 1.5 3.2 1.9 16.2 1.4 2.6 4.1 1.7 3.7 18.6 20.6 11.9 25.4 26.4 11.4 14.1 10.4 8.8 8.1 12.0 24.3 14.7 25.6 34.0 24.2 22.2 9.2 29.5 10.0 6.2 27.3 15.8 11.0 11.4 22.8 9.6 18.4 43.8 23.5 28.2 27.7 5.9 18.6 16.2 20.1 24.2 16.9 37.0 13.7 26.6 22.7 17.7 19.0 44.9 24.5 14.0 30.4 15.0 34.8 30.4 25.2 25.0 23.5 4.1 30.1 21.4 27.2 26.8 27.0 21.4 8.4 36.5 20.8 23.7 18.6 29.8 32.0 15.8 24.8 29.0 23.7 31.7 13.9 11.1 35.2 0.0 20.4 17.6 9.3 12.5 11.9 16.3 34.2 24.0 29.8 23.1 27.8 MIA3 "FLJ39207, KIAA0268, TANGO, TANGO1, UNQ6077" ENSG00000154305 "MIA SH3 domain ER export factor 3" Q5JRA6 1 222618097-222668007 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA055922, HPA056816" Supported Enhanced Vesicles NA NA 1400000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" Vesicles "HPA055922: AB_2682971, HPA056816: AB_2683243" "unprognostic (1.24e-1)" "unprognostic (7.42e-2)" "unprognostic (1.43e-1)" "unprognostic (6.60e-2)" "unprognostic (1.86e-2)" "unprognostic (8.57e-2)" "unprognostic (1.28e-3)" "unprognostic (5.41e-2)" "unprognostic (2.56e-1)" "unprognostic (5.65e-2)" "unprognostic (6.73e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (3.57e-2)" "unprognostic (1.83e-1)" "unprognostic (8.62e-3)" "unprognostic (3.26e-1)" 25.6 22.0 11.0 23.4 13.1 33.2 21.4 12.9 14.9 23.9 13.2 24.3 23.9 23.7 29.2 13.7 16.0 20.6 20.6 10.9 13.6 21.1 74.5 21.5 26.9 10.8 12.3 25.4 38.7 30.1 15.2 23.1 11.7 39.3 29.5 24.4 33.2 22.1 23.7 17.4 25.9 23.8 10.7 27.3 45.0 36.5 11.5 25.7 31.7 20.5 26.2 21.0 14.1 12.8 24.8 18.8 26.5 42.5 92.8 47.1 46.5 34.8 49.4 36.2 43.1 16.6 26.2 24.0 33.0 41.8 20.5 39.9 28.5 31.3 37.8 38.1 21.6 27.7 21.5 31.5 88.6 50.7 34.7 45.2 35.0 35.9 60.8 44.8 41.4 28.9 34.8 44.4 30.7 15.9 34.3 33.8 33.2 76.8 27.5 24.4 70.8 47.8 23.1 22.8 30.4 31.3 38.6 36.2 30.4 36.2 38.2 37.5 31.7 27.5 17.9 44.5 41.3 48.4 30.9 23.8 36.7 25.4 37.5 26.8 15.6 36.5 17.6 22.4 17.7 20.7 14.7 17.5 11.7 18.6 16.4 17.8 27.1 22.5 26.0 13.2 19.2 13.5 11.0 13.1 12.9 14.9 10.9 13.6 10.8 12.3 11.7 10.7 11.5 12.8 48.5 70.5 49.6 31.3 46.9 18.7 26.8 20.4 29.0 60.9 24.3 35.3 65.0 25.8 47.1 5.5 31.3 28.6 73.8 35.2 0.0 25.1 37.0 34.9 72.5 36.4 60.4 26.3 51.4 34.8 17.0 53.0 79.5 42.0 17.7 44.2 25.4 63.3 20.4 45.4 58.0 95.3 32.6 22.0 14.0 24.9 37.0 32.9 19.6 35.6 32.1 31.8 44.3 41.2 29.1 26.4 25.8 48.9 54.4 39.0 41.3 19.4 44.7 41.5 19.7 57.9 46.6 55.7 42.1 21.9 16.1 35.8 47.8 70.2 24.6 29.4 MIB1 "DIP-1, KIAA1323, MIB, ZZANK2, ZZZ6" ENSG00000101752 "Mindbomb E3 ubiquitin protein ligase 1" Q86YT6 18 21704957-21870953 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 121.2;Oligodendrocytes: 109.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "REH: 121.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019100, CAB037044" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Vesicles "CAB037044: AB_1841007, HPA019100: AB_1853934" "unprognostic (1.38e-1)" "unprognostic (6.92e-2)" "unprognostic (7.29e-2)" "unprognostic (6.99e-2)" "unprognostic (5.66e-2)" "unprognostic (3.23e-2)" "unprognostic (8.45e-3)" "unprognostic (2.70e-1)" "unprognostic (5.42e-2)" "unprognostic (4.69e-2)" "unprognostic (3.78e-2)" "unprognostic (4.70e-2)" "unprognostic (8.33e-3)" "unprognostic (4.91e-3)" "unprognostic (1.73e-1)" "unprognostic (4.86e-2)" "unprognostic (1.85e-2)" 8.1 6.3 9.1 6.0 9.1 4.9 11.2 9.2 8.5 11.0 8.0 7.1 5.1 13.0 9.5 8.0 7.1 8.6 6.0 8.4 9.2 11.1 10.4 7.2 7.6 9.5 10.2 11.7 8.1 9.8 5.2 11.0 8.6 10.1 7.0 8.3 8.4 8.5 5.8 9.1 5.2 10.2 10.1 7.2 7.6 8.7 10.3 11.5 13.6 7.0 7.9 8.4 8.2 9.6 19.9 7.6 36.4 25.8 19.5 23.0 9.0 15.6 17.2 10.8 15.6 11.3 7.1 16.9 14.1 21.4 11.8 13.2 21.4 21.0 24.4 22.4 10.4 18.8 9.7 15.9 15.8 38.3 7.8 14.8 23.0 12.6 32.0 16.0 27.8 6.6 26.5 47.5 17.2 9.5 18.9 14.7 9.5 12.2 10.2 121.1 30.3 42.5 18.7 16.9 12.1 30.1 26.8 12.4 13.9 18.6 8.8 25.1 23.9 27.8 14.2 11.7 21.1 25.6 9.5 25.4 11.8 24.1 16.9 0.7 0.3 0.1 0.2 0.1 0.2 0.2 0.3 0.2 0.1 0.1 0.2 0.1 0.3 0.5 0.1 0.2 0.4 0.1 9.1 9.1 9.2 8.5 8.4 9.2 9.5 10.2 8.6 10.1 10.3 9.6 35.7 48.1 22.7 68.2 11.9 21.9 15.1 19.8 24.5 28.8 24.1 19.7 18.1 25.8 31.8 16.5 25.0 13.3 18.2 20.8 3.9 13.4 7.0 29.0 59.2 30.8 24.0 23.1 106.7 12.9 7.5 33.1 10.2 32.4 14.5 16.8 24.3 30.0 12.9 15.2 92.6 17.1 26.4 17.2 16.2 5.6 20.5 14.2 26.6 67.5 19.4 17.7 15.5 121.2 109.6 18.8 7.0 24.8 18.1 48.5 8.7 15.9 30.6 14.5 0.0 35.4 26.9 26.2 12.0 23.4 24.6 25.3 14.5 21.8 10.4 25.3 MINDY4 "C7orf67, FAM188B, FLJ22374" ENSG00000106125 "MINDY lysine 48 deubiquitinase 4" Q4G0A6 7 30771417-30892387 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Collecting duct cells: 12.9;Endometrial ciliated cells: 36.7;Endometrial stromal cells: 8.9;Respiratory ciliated cells: 18.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "K-562: 19.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019475, HPA030129, HPA030130" Approved Supported Vesicles,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 1: K-562 - Erythropoiesis" "Cluster 49: Ciliated cells - Cilium organization" "Vesicles, Cytosol" "HPA019475: AB_1848806, HPA030129: AB_10599621, HPA030130: AB_10601565" "unprognostic (2.96e-1)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "unprognostic (2.10e-2)" "unprognostic (1.64e-1)" "unprognostic (4.07e-1)" "unprognostic (6.01e-3)" "unprognostic (3.81e-2)" "unprognostic (5.25e-3)" "unprognostic (1.97e-1)" "unprognostic (5.59e-3)" "unprognostic (2.96e-2)" "unprognostic (1.92e-1)" "unprognostic (9.55e-2)" "unprognostic (1.12e-2)" "unprognostic (1.05e-1)" "unprognostic (2.18e-1)" 6.7 3.7 2.1 1.2 3.5 2.4 4.4 0.4 4.2 5.7 10.6 4.6 1.3 5.4 8.4 2.9 11.5 5.6 4.7 1.9 1.8 4.9 2.1 9.5 1.2 2.8 4.5 8.9 3.4 4.8 5.6 3.3 2.2 5.9 2.1 2.1 3.1 8.1 2.3 3.2 2.2 5.9 1.8 1.2 3.2 9.0 2.4 1.2 6.7 3.5 0.9 4.3 3.7 2.5 2.4 6.0 3.1 9.5 2.7 10.3 4.5 3.5 6.0 2.6 2.2 0.0 4.4 0.0 3.9 2.3 3.6 2.6 2.1 2.0 2.5 0.0 3.5 1.9 3.2 0.0 3.3 2.7 1.3 5.3 3.1 7.7 1.5 0.2 3.8 1.7 19.2 1.1 2.2 0.0 1.5 0.8 8.9 8.5 1.4 0.4 0.0 0.6 7.1 1.2 5.7 7.7 2.3 12.5 1.3 3.5 6.4 2.0 2.3 0.1 1.4 2.7 1.5 2.5 3.5 0.0 4.9 0.1 11.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 2.1 3.5 0.4 4.2 1.9 1.8 2.8 4.5 2.2 1.8 2.4 2.5 5.2 9.6 3.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.1 2.4 0.0 0.0 1.8 12.9 0.0 2.3 0.5 0.0 3.9 2.8 0.0 36.7 8.9 2.3 0.0 0.0 0.0 1.3 4.1 2.7 0.0 3.9 2.5 4.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 2.4 18.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.5 0.2 4.1 0.0 0.0 MITD1 LOC129531 ENSG00000158411 "Microtubule interacting and trafficking domain containing 1" Q8WV92 2 99161427-99181058 "Predicted intracellular proteins" "Cell cycle, Cell division, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036162, HPA036163" Approved Enhanced Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA036162: AB_10672236, HPA036163: AB_2674978" "prognostic favorable (5.96e-4)" "unprognostic (1.67e-2)" "unprognostic (3.09e-1)" "unprognostic (2.79e-1)" "unprognostic (2.02e-1)" "unprognostic (8.96e-2)" "prognostic unfavorable (1.47e-6)" "unprognostic (1.39e-1)" "unprognostic (5.35e-2)" "unprognostic (1.01e-2)" "unprognostic (1.09e-1)" "unprognostic (6.31e-3)" "prognostic unfavorable (1.32e-11)" "unprognostic (2.38e-1)" "unprognostic (2.40e-1)" "unprognostic (6.91e-2)" "prognostic favorable (5.46e-8)" 17.9 16.8 12.3 25.1 12.9 13.2 17.1 12.3 15.5 17.2 11.8 17.5 15.4 16.8 14.3 17.9 15.8 12.7 13.6 11.9 12.9 18.7 17.3 14.2 36.5 13.0 12.7 17.0 11.7 9.1 11.0 16.6 12.9 13.5 20.0 22.1 13.5 11.9 10.7 15.8 19.1 17.0 12.4 22.3 17.4 7.0 12.7 27.0 15.1 11.2 29.1 16.8 16.2 13.7 58.0 15.3 30.5 11.8 35.1 45.2 41.9 27.1 37.8 37.2 50.3 18.8 47.6 40.0 30.4 22.2 84.9 43.0 30.0 29.9 61.7 57.2 20.6 35.4 22.3 40.4 52.2 60.2 20.1 35.9 25.4 32.6 31.2 34.3 42.4 37.8 29.6 24.1 34.0 13.8 57.8 88.5 25.8 37.1 30.0 32.4 43.8 34.7 47.2 32.1 10.0 14.7 26.5 24.3 35.0 52.8 12.9 47.1 32.1 23.0 30.2 24.3 34.1 28.2 23.6 55.5 41.7 50.2 23.4 19.2 24.7 18.2 17.5 22.8 19.7 30.6 24.8 20.8 22.0 28.4 23.6 19.3 28.0 26.0 21.8 29.8 23.1 12.8 12.3 12.9 12.3 15.5 11.9 12.9 13.0 12.7 12.9 12.4 12.7 13.7 31.0 25.6 19.9 22.9 51.2 18.9 30.3 78.2 22.2 13.4 19.5 22.9 12.3 31.5 41.6 35.0 14.6 48.2 39.1 28.1 45.0 46.9 18.8 28.2 34.8 33.1 15.7 27.3 18.3 61.2 34.9 27.6 19.9 24.7 30.4 20.2 30.0 31.2 51.0 11.8 16.9 25.5 40.7 24.5 22.3 6.2 51.0 31.0 23.2 11.2 50.5 26.2 40.2 15.6 38.4 57.3 33.5 39.5 23.3 20.2 32.9 63.4 34.5 55.4 39.5 22.4 24.4 14.4 15.5 20.0 17.5 22.6 42.4 26.4 27.5 19.6 MKLN1 TWA2 ENSG00000128585 "Muskelin 1" Q9UL63 7 131110096-131496632 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 455.1;Excitatory neurons: 336.5;Inhibitory neurons: 256.4;Oligodendrocyte precursor cells: 369.5;Oligodendrocytes: 332.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 9.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 9.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022817, HPA041810" Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" Vesicles "HPA022817: AB_1853974, HPA041810: AB_2677686" "unprognostic (1.97e-1)" "unprognostic (2.83e-2)" "unprognostic (1.23e-1)" "unprognostic (3.92e-3)" "unprognostic (1.03e-1)" "unprognostic (4.20e-2)" "unprognostic (1.44e-3)" "unprognostic (4.58e-2)" "unprognostic (1.94e-2)" "unprognostic (1.97e-1)" "unprognostic (2.43e-3)" "unprognostic (1.55e-1)" "unprognostic (9.18e-3)" "unprognostic (1.70e-1)" "unprognostic (4.13e-1)" "unprognostic (1.13e-2)" "unprognostic (2.32e-1)" 12.6 12.1 20.0 6.9 22.3 9.1 13.6 23.1 17.8 10.8 19.1 7.5 9.0 10.1 11.8 7.5 11.9 7.1 8.9 17.1 22.3 13.8 14.7 7.6 8.8 19.4 24.7 13.8 7.7 10.0 4.6 11.6 22.8 16.0 7.3 22.0 11.3 13.4 10.5 9.6 8.4 9.0 18.8 8.7 8.4 9.5 21.4 8.6 11.3 13.5 7.7 7.2 5.4 21.5 14.1 16.0 13.6 13.8 32.8 29.6 8.5 13.3 30.7 14.8 18.8 7.3 11.9 14.6 9.0 16.7 29.3 9.5 14.4 13.1 24.2 14.5 7.0 6.2 13.1 8.5 15.7 10.4 8.7 17.7 8.8 20.6 10.0 15.9 13.7 8.8 23.3 10.2 18.6 5.2 12.3 11.1 15.5 11.4 8.3 7.7 16.0 10.1 16.4 8.1 7.0 15.2 25.7 25.7 12.9 14.1 5.0 12.9 14.1 11.5 6.5 21.1 11.0 24.7 10.0 24.6 39.6 12.3 17.2 1.2 0.7 1.4 1.1 0.9 0.8 0.9 1.1 0.9 0.8 1.6 1.7 1.4 9.5 0.7 1.3 1.2 0.7 0.5 20.0 22.3 23.1 17.8 17.1 22.3 19.4 24.7 22.8 18.8 21.4 21.5 54.4 51.3 43.7 455.1 42.6 44.1 29.3 22.9 31.9 49.7 34.6 21.5 24.9 38.6 27.4 46.0 70.9 17.3 37.6 33.2 7.9 23.0 5.7 30.5 60.4 50.5 37.1 38.9 336.5 23.7 17.4 46.3 36.7 46.9 34.2 42.9 64.2 78.3 21.7 53.8 256.4 29.4 28.5 41.9 52.1 7.8 68.0 35.1 35.6 210.8 44.9 44.1 26.8 369.5 332.5 27.1 36.5 84.2 40.2 49.3 38.7 31.4 25.9 64.9 85.5 64.3 56.9 41.1 28.0 28.9 45.9 14.8 37.9 35.9 28.4 39.1 MMD "MMA, PAQR11" ENSG00000108960 "Monocyte to macrophage differentiation associated" Q15546 17 55392622-55421924 "Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "adipose tissue: 152.2;brain: 87.5" "Cell type enhanced" "Detected in many" "Kupffer cells: 56.4;Macrophages: 85.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 110.0;HSkMC: 199.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026978 Approved Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA026978: AB_2672068" "unprognostic (1.33e-1)" "unprognostic (2.92e-2)" "prognostic favorable (3.52e-5)" "prognostic unfavorable (3.88e-4)" "unprognostic (2.48e-1)" "unprognostic (4.16e-2)" "prognostic unfavorable (6.39e-5)" "unprognostic (8.07e-3)" "unprognostic (6.67e-2)" "unprognostic (2.15e-1)" "unprognostic (1.30e-1)" "unprognostic (1.06e-3)" "prognostic unfavorable (2.85e-4)" "unprognostic (3.71e-3)" "unprognostic (7.93e-2)" "prognostic unfavorable (8.62e-4)" "unprognostic (1.12e-2)" 152.2 13.3 54.2 15.7 55.9 14.1 28.4 11.6 58.5 4.8 5.4 13.4 10.9 6.2 9.7 7.2 4.2 9.4 6.5 87.5 19.7 8.5 13.2 10.0 17.8 16.3 29.2 2.8 3.5 3.7 4.8 21.4 16.1 6.2 12.9 12.8 4.9 7.9 3.4 5.3 10.1 11.4 24.2 16.5 5.4 17.0 21.6 8.2 6.6 8.0 12.1 11.6 4.0 27.2 20.1 46.3 67.0 13.5 110.0 86.0 39.2 13.6 5.2 7.2 10.2 7.4 53.8 30.1 39.6 4.5 20.1 1.5 18.8 14.3 14.9 41.5 9.5 11.0 2.5 85.2 29.8 10.8 3.2 199.4 4.5 10.1 11.4 15.7 9.0 27.4 4.4 20.5 15.1 2.8 29.7 8.2 20.6 3.3 15.6 12.4 46.9 10.0 19.7 5.0 7.0 72.8 5.0 7.1 10.9 41.5 15.4 17.3 9.6 18.7 26.6 15.5 14.0 13.1 6.2 45.7 26.7 8.5 15.2 14.2 1.5 1.9 1.7 2.1 4.9 4.5 1.8 3.3 4.3 5.0 3.1 3.3 4.6 2.9 1.9 1.3 2.1 17.5 54.2 55.9 11.6 58.5 87.5 19.7 16.3 29.2 16.1 24.2 21.6 27.2 15.5 3.2 0.6 5.2 20.3 5.4 23.7 9.3 5.2 28.2 3.3 3.3 4.6 11.5 2.7 7.3 4.2 11.5 12.2 3.4 15.6 27.7 2.5 4.8 8.9 16.4 7.8 27.3 36.5 1.3 18.8 12.7 2.6 8.7 0.0 3.5 19.6 17.9 37.6 16.8 11.5 6.8 8.2 56.4 35.9 4.0 1.8 85.9 7.2 14.0 48.6 14.5 12.3 7.5 7.2 17.3 1.6 3.4 12.1 26.2 2.3 9.8 2.4 10.2 19.7 5.2 11.4 28.9 23.3 3.1 17.5 20.0 17.7 1.3 8.6 6.1 MMP1 CLG ENSG00000196611 "Matrix metallopeptidase 1" P03956 11 102789401-102798160 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Collagen degradation, Host-virus interaction" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 75.7;stomach 1: 47.6;urinary bladder: 52.2" "Cell type enriched" "Detected in many" 10 "Pancreatic endocrine cells: 2239.5" "Cancer enhanced" "Detected in many" "head and neck cancer: 344.2" "Region enriched" "Detected in single" 7 "cerebral cortex: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 1139.1;HBF TERT88: 1094.4;HUVEC TERT2: 2954.4;WM-115: 1454.1" "Not detected" "Not detected" HPA004920 Approved Vesicles "Secreted to extracellular matrix" NA NA 7730000 55000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "HPA004920: AB_2667293" "unprognostic (4.11e-3)" "prognostic unfavorable (4.66e-4)" "unprognostic (4.20e-3)" "unprognostic (1.19e-3)" "unprognostic (6.46e-2)" "unprognostic (6.50e-2)" "prognostic unfavorable (4.22e-6)" "unprognostic (7.83e-3)" "unprognostic (2.94e-2)" "unprognostic (5.44e-2)" "unprognostic (1.11e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.86e-10)" "unprognostic (1.67e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-2)" "unprognostic (5.11e-2)" 0.3 0.1 0.0 26.7 0.0 0.3 0.2 0.0 1.3 0.1 0.0 6.1 7.9 10.7 0.0 4.2 0.1 75.7 0.4 0.0 0.1 1.0 0.8 6.7 0.1 0.0 0.0 0.0 1.8 0.0 0.1 7.2 0.0 0.4 6.8 0.0 6.9 0.2 0.0 0.6 13.0 1.2 0.0 2.1 47.6 0.1 0.1 0.3 0.2 0.0 1.7 52.2 0.2 0.0 0.0 0.0 0.0 1.0 0.0 1.1 0.0 517.1 1139.1 456.6 118.2 9.1 1.0 0.0 5.2 275.5 175.2 4.6 0.0 160.0 1094.4 0.0 1.0 0.0 0.0 0.0 2.9 0.0 0.5 0.3 0.8 470.1 39.6 0.1 2954.4 0.0 1.5 0.5 0.3 0.0 0.0 0.0 0.4 189.3 20.8 0.0 0.1 0.0 0.7 2.2 0.0 0.1 4.8 0.0 1.6 0.1 0.5 0.0 155.0 374.1 0.6 16.8 1.3 0.1 0.0 0.0 8.8 0.0 1454.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.3 3.2 2.6 0.0 0.2 2.3 22.4 90.4 0.0 0.0 0.0 0.0 0.1 30.0 15.8 3.7 0.0 0.0 0.0 0.2 0.0 143.7 0.0 0.1 0.2 113.2 0.0 0.0 0.1 204.8 0.1 11.5 25.5 2.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.0 1.9 0.4 0.0 0.0 15.5 0.0 0.0 4.2 0.0 0.0 0.0 0.0 2239.5 1.2 0.0 0.0 30.9 0.7 0.2 1.3 0.0 0.0 1.8 10.5 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.1 44.3 MMP16 "C8orf57, DKFZp761D112, MT3-MMP" ENSG00000156103 "Matrix metallopeptidase 16" P51512 8 88032011-88328025 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 2402.1" "Cancer enhanced" "Detected in many" "glioma: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 29.4;HUVEC TERT2: 12.8;SH-SY5Y: 16.2;U-138 MG: 13.7;WM-115: 28.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023693 Uncertain Approved Vesicles,Cytosol "Secreted to extracellular matrix" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol Vesicles "HPA023693: AB_1854025" "unprognostic (2.58e-1)" "unprognostic (2.42e-2)" "unprognostic (1.38e-1)" "unprognostic (1.87e-1)" "unprognostic (7.09e-2)" "unprognostic (3.31e-2)" "unprognostic (2.39e-3)" "unprognostic (1.45e-3)" "unprognostic (2.46e-1)" "unprognostic (2.61e-1)" "unprognostic (9.42e-2)" "unprognostic (2.92e-1)" "unprognostic (2.09e-8)" "unprognostic (6.90e-3)" "unprognostic (1.16e-1)" "unprognostic (3.62e-1)" "unprognostic (2.19e-3)" 0.7 0.3 4.6 0.3 5.8 0.0 1.8 2.2 5.4 1.7 0.0 0.8 0.1 1.6 0.6 0.4 0.6 2.6 0.8 5.1 3.9 0.1 0.1 0.2 0.2 1.0 1.5 1.0 0.6 0.2 0.5 1.0 1.3 0.9 0.4 0.4 0.3 0.7 0.1 0.2 0.3 1.3 1.4 0.4 0.3 0.4 3.0 0.4 1.0 0.5 0.2 0.9 0.5 3.3 0.0 0.2 7.9 29.4 1.0 2.0 0.0 10.9 1.6 3.0 1.8 0.0 0.1 0.0 0.0 4.9 1.8 0.0 5.8 0.0 3.7 0.0 3.4 0.0 0.0 0.0 2.4 0.0 0.5 1.4 0.0 4.4 1.3 5.4 12.8 0.1 0.0 1.1 1.7 0.0 0.0 0.0 1.7 0.0 3.0 0.3 0.6 0.0 0.6 0.1 0.2 16.2 0.0 0.0 0.2 2.2 1.1 0.0 7.1 13.7 7.7 0.2 4.2 0.0 0.0 0.0 5.7 0.0 28.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 5.8 2.2 5.4 5.1 3.9 1.0 1.5 1.3 1.4 3.0 3.3 2.2 0.0 0.0 20.5 0.1 1.1 0.0 0.0 0.6 4.4 0.8 1.4 1.0 0.0 0.0 0.0 2.1 0.1 0.1 0.0 1.9 0.0 6.5 0.5 15.9 5.2 0.0 0.0 443.4 0.0 0.1 16.0 0.0 0.4 0.0 1.9 1.4 0.0 0.4 1.7 300.3 0.0 0.0 0.0 1.6 6.5 0.9 0.4 1.8 10.3 0.0 3.0 0.0 2402.1 13.0 0.1 0.0 1.2 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.7 2.9 0.0 1.1 0.2 0.1 0.0 0.2 3.4 0.0 0.1 MMP19 "MMP18, RASI-1" ENSG00000123342 "Matrix metallopeptidase 19" Q99542 12 55835433-55842966 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Angiogenesis, Collagen degradation, Differentiation" "Developmental protein, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 58.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 54.4;Fibroblasts: 52.8;Hofbauer cells: 30.8;Kupffer cells: 35.7;Langerhans cells: 100.7;Macrophages: 61.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in single" "thalamus: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "BEWO: 75.6" "Region enriched" "Detected in many" 5 "olfactory bulb: 7.2" "Low region specificity" "Detected in all" HPA070804 Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" NA NA 2100000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum, Vesicles" "HPA070804: AB_2686315" "unprognostic (2.61e-1)" "unprognostic (6.56e-2)" "unprognostic (2.28e-2)" "unprognostic (2.42e-1)" "unprognostic (4.77e-3)" "unprognostic (4.77e-3)" "unprognostic (2.01e-2)" "unprognostic (4.03e-2)" "unprognostic (2.85e-2)" "unprognostic (4.30e-2)" "unprognostic (2.37e-1)" "unprognostic (2.09e-1)" "prognostic unfavorable (8.56e-9)" "unprognostic (5.06e-3)" "unprognostic (1.28e-3)" "unprognostic (2.73e-2)" "unprognostic (4.00e-2)" 58.5 3.6 0.0 11.4 0.1 0.7 18.3 0.0 0.3 10.4 0.5 7.3 1.2 20.7 0.5 2.3 17.2 25.6 8.8 0.1 0.1 5.7 2.7 25.4 2.8 0.1 0.1 11.9 7.2 0.5 0.8 10.8 0.2 3.3 3.3 0.1 3.1 2.3 0.9 5.5 8.7 8.7 0.1 27.4 9.6 0.4 1.3 2.9 4.4 0.6 6.9 9.6 6.2 0.1 1.5 0.0 0.2 0.0 7.8 12.4 75.6 10.1 10.6 3.9 4.4 0.6 0.6 0.0 0.0 12.8 0.3 0.0 0.0 3.0 4.0 0.8 0.0 0.0 0.3 0.1 6.5 0.0 0.6 12.1 0.4 1.9 2.4 6.2 0.7 0.0 0.2 0.1 11.2 0.0 0.0 0.2 0.3 0.0 0.2 0.0 2.8 0.0 1.7 4.7 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.2 15.7 2.2 5.0 0.2 0.3 0.1 0.0 0.0 8.4 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.1 0.2 0.1 1.3 0.1 2.8 0.0 4.6 0.7 1.3 7.1 0.3 1.9 0.6 0.4 0.3 0.3 0.7 11.5 3.3 0.0 4.2 18.6 0.7 0.0 0.0 0.3 0.5 2.4 20.8 1.5 0.0 0.0 0.2 0.5 54.4 52.8 1.1 1.7 2.5 0.4 3.6 0.7 30.8 0.0 0.2 0.1 0.0 35.7 100.7 0.9 5.9 61.2 12.4 1.9 22.5 0.4 0.0 0.0 0.3 0.1 0.0 5.3 1.0 0.3 0.0 0.1 1.5 1.7 0.0 3.8 7.6 0.2 0.2 1.0 4.3 18.7 0.9 0.2 0.0 0.4 MMP2 "CLG4, CLG4A, TBE-1" ENSG00000087245 "Matrix metallopeptidase 2" P08253 16 55389700-55506691 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 1062.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 222.4;Extravillous trophoblasts: 467.9;Fibroblasts: 815.9;Leydig cells: 340.2;Peritubular cells: 419.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 5619.3;ASC TERT1: 1623.2;hTERT-RPE1: 6400.4;U-87 MG: 1812.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001939, CAB002788" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 1600000000 220000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB002788: , HPA001939: AB_1079395" "unprognostic (7.26e-2)" "unprognostic (1.36e-3)" "unprognostic (1.66e-1)" "unprognostic (2.14e-3)" "unprognostic (5.03e-2)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (9.36e-3)" "unprognostic (4.81e-3)" "unprognostic (3.79e-2)" "unprognostic (4.59e-3)" "unprognostic (6.12e-2)" "unprognostic (1.28e-3)" "unprognostic (1.59e-2)" "unprognostic (8.00e-2)" "unprognostic (8.98e-2)" "unprognostic (4.63e-2)" 518.9 68.3 3.9 135.1 4.0 1.2 328.9 4.9 7.8 514.1 9.4 173.8 57.4 453.6 192.6 121.5 190.6 1062.9 212.8 3.6 5.3 43.7 15.6 279.7 28.1 7.6 4.9 271.1 42.8 13.8 14.7 225.0 5.4 116.8 171.3 11.4 124.1 137.5 60.8 455.6 177.3 468.5 6.7 58.3 134.0 49.6 8.6 19.8 113.5 66.1 30.3 660.8 238.1 10.0 6.5 3.9 192.0 2.4 5619.3 1623.2 312.7 501.4 1146.1 99.4 79.0 0.2 2.1 0.5 391.7 891.0 37.0 54.2 1.2 4.6 57.0 0.7 0.9 0.7 12.9 3.0 530.6 0.4 14.8 1396.8 1.7 512.4 4.4 6400.4 651.1 0.5 0.7 2.4 334.7 0.0 0.4 8.2 152.4 0.5 1.6 0.4 46.1 0.9 16.1 7.6 3.2 345.0 93.3 0.8 2.1 849.0 1.6 36.0 924.6 1546.0 144.9 300.5 66.9 1.0 0.6 2.2 1812.3 28.3 289.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.0 4.9 7.8 3.6 5.3 7.6 4.9 5.4 6.7 8.6 10.0 38.4 0.0 0.5 0.0 0.0 122.1 14.1 48.8 9.1 30.5 3.1 16.8 4.4 0.0 3.1 11.0 0.0 5.6 0.5 0.1 0.0 2.5 12.5 7.7 222.4 46.9 28.2 0.0 0.0 0.4 467.9 815.9 12.2 5.4 0.0 0.0 13.2 0.1 28.2 1.7 0.2 0.1 2.0 1.6 180.7 40.2 340.2 11.8 128.1 27.2 0.0 7.7 0.0 5.0 0.0 9.3 0.0 419.0 2.8 5.6 0.0 0.2 1.1 2.5 13.1 80.0 65.3 1.2 2.8 6.6 102.3 17.2 10.3 35.2 0.0 4.4 MMP3 "STMY, STMY1" ENSG00000149968 "Matrix metallopeptidase 3" P08254 11 102835801-102843609 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 90.7;salivary gland: 286.1" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 20.4;Basal respiratory cells: 25.8;Early spermatids: 24.2;Extravillous trophoblasts: 13.4;Fibroblasts: 17.9;Prostatic glandular cells: 11.9;Smooth muscle cells: 10.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 59.9" "Region enriched" "Detected in some" 4 "thalamus: 7.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "BJ: 1545.7;BJ hTERT+: 4229.3;fHDF/TERT166: 1846.6" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hippocampal formation: 3.2" HPA007875 Uncertain Supported Vesicles "Secreted to extracellular matrix" NA NA 2540000 460000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA007875: AB_1079396" "unprognostic (2.27e-1)" "prognostic unfavorable (9.73e-4)" "unprognostic (1.63e-3)" "unprognostic (5.11e-3)" "unprognostic (3.78e-1)" "unprognostic (5.11e-2)" "unprognostic (5.26e-6)" "unprognostic (3.46e-2)" "unprognostic (7.14e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (4.09e-4)" "unprognostic (3.26e-2)" "unprognostic (1.22e-15)" "unprognostic (3.17e-1)" "unprognostic (1.55e-1)" "unprognostic (3.43e-2)" "unprognostic (2.34e-1)" 90.7 0.1 0.3 20.1 0.4 0.0 36.6 0.2 1.6 0.3 0.1 6.1 2.4 38.1 0.2 0.8 0.2 1.9 0.2 0.4 1.6 0.4 1.6 0.3 0.0 0.4 0.4 0.1 0.3 0.1 0.9 0.4 0.3 2.2 2.3 0.0 286.1 2.2 39.6 63.7 4.5 1.6 0.3 0.0 10.5 0.1 7.3 0.1 2.6 0.4 1.3 13.9 0.5 0.3 0.0 0.0 0.0 0.1 0.4 0.0 0.0 1545.7 4229.3 27.0 8.7 0.1 0.2 0.0 0.0 1846.6 96.9 0.0 0.1 0.1 45.1 0.0 0.0 0.0 0.0 1.0 0.7 0.0 0.0 4.6 0.2 122.0 5.3 0.0 0.0 0.0 0.2 0.3 4.7 0.0 0.0 0.0 0.2 0.4 0.9 0.0 0.2 0.0 0.1 0.0 0.1 0.0 2.3 0.0 0.0 0.9 0.0 0.3 0.0 140.5 13.1 1.6 0.5 0.0 0.0 0.2 56.8 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 1.6 0.4 1.6 0.4 0.4 0.3 0.3 7.3 0.3 0.0 3.2 0.0 0.0 0.0 8.4 20.4 25.8 0.0 0.0 0.1 0.1 0.3 4.3 7.6 0.0 0.0 0.1 0.0 0.0 0.0 0.8 24.2 0.0 0.3 0.5 0.0 0.0 0.2 1.4 13.4 17.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 4.1 0.0 2.2 1.2 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 3.5 4.0 0.0 0.0 11.9 1.0 0.9 0.1 0.0 0.0 1.8 10.2 0.0 1.8 0.0 3.4 0.3 0.6 0.0 0.8 7.4 MMP7 "MPSL1, PUMP-1" ENSG00000137673 "Matrix metallopeptidase 7" P09237 11 102520508-102530750 "Cancer-related genes, Enzymes, Plasma proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 509.9;salivary gland: 267.9;urinary bladder: 211.2" "Cell type enriched" "Detected in many" 8 "Ductal cells: 8176.2" "Cancer enhanced" "Detected in all" "pancreatic cancer: 352.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 145.9;CAPAN-2: 815.9;EFO-21: 189.8;RPTEC TERT1: 350.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025869, HPA051358" Supported Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" NA NA 2810000 35000 "Cluster 5: Breast - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Vesicles" "CAB025869: , HPA051358: AB_2681452" "unprognostic (1.06e-3)" "unprognostic (9.51e-2)" "unprognostic (4.15e-2)" "unprognostic (1.38e-1)" "unprognostic (7.70e-3)" "unprognostic (7.28e-2)" "prognostic unfavorable (2.53e-4)" "prognostic unfavorable (3.38e-4)" "unprognostic (3.96e-2)" "unprognostic (5.63e-2)" "unprognostic (6.59e-3)" "unprognostic (1.51e-1)" "unprognostic (6.36e-3)" "unprognostic (1.42e-2)" "unprognostic (5.54e-2)" "unprognostic (1.48e-1)" "unprognostic (1.46e-1)" 3.8 0.1 0.0 2.0 0.0 0.3 168.7 0.0 0.3 13.3 0.0 1.6 0.6 97.4 27.9 21.3 91.2 509.9 0.2 0.0 0.0 140.2 3.4 31.6 1.9 0.0 0.0 0.7 85.2 0.0 0.3 0.8 0.0 54.0 1.0 0.0 267.9 34.9 0.1 32.4 0.6 4.8 0.0 0.2 7.3 0.6 0.4 3.3 0.4 0.0 29.3 211.2 1.7 0.0 0.2 145.9 0.0 0.4 0.0 0.0 0.2 0.0 2.1 0.1 0.1 1.9 815.9 0.0 189.8 0.0 0.0 1.1 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.6 1.0 0.1 0.2 0.7 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.5 11.8 0.0 0.0 0.0 0.0 350.1 1.0 0.0 0.0 0.0 0.0 0.0 3.9 0.3 0.1 0.0 0.7 3.0 0.0 1.6 0.1 0.6 0.4 1.0 5.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 86.6 43.3 0.0 1.5 1.0 382.2 135.4 1.2 0.0 124.2 93.7 0.7 100.1 401.2 1017.0 0.0 0.7 2.9 1.2 0.0 8176.2 6.1 62.1 3.3 8.8 0.0 0.0 0.0 209.4 0.3 3.4 0.0 124.6 2.5 0.0 0.0 0.0 98.0 0.0 0.0 0.0 38.7 0.6 0.3 10.3 11.8 12.6 0.0 0.0 65.2 0.0 0.0 0.0 0.0 850.9 0.0 0.0 0.1 603.3 0.0 33.9 72.6 0.0 0.0 0.0 31.4 0.1 0.2 17.0 2.4 0.8 3.6 0.0 2.3 840.8 MMP8 CLG1 ENSG00000118113 "Matrix metallopeptidase 8" P22894 11 102711796-102727050 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 36 "bone marrow: 501.1" "Group enriched" "Detected in some" 6 "Hofbauer cells: 4.0;Macrophages: 1.5" "Cancer enriched" "Detected in single" 17 "melanoma: 5.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.7" "Lineage enhanced" "Detected in single" "monocytes: 1.7" "Cell line enriched" "Detected in some" 8 "WM-115: 70.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021221, HPA021763, HPA022935" Enhanced Approved Vesicles "Secreted to extracellular matrix" NA NA 360000 "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 17: WM-115 - Nervous system development" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA021221: AB_1854043, HPA021763: , HPA022935: AB_1854044" "unprognostic (3.03e-1)" "unprognostic (8.49e-5)" "unprognostic (1.08e-2)" "unprognostic (3.95e-3)" "unprognostic (1.80e-1)" "unprognostic (1.01e-2)" "unprognostic (7.68e-3)" "unprognostic (1.27e-1)" "unprognostic (4.92e-2)" "unprognostic (6.64e-3)" "unprognostic (2.45e-6)" "unprognostic (2.33e-4)" "unprognostic (1.33e-1)" "unprognostic (4.97e-1)" "unprognostic (2.30e-2)" 0.5 0.0 0.0 0.3 0.1 501.1 0.2 0.1 0.2 0.0 0.2 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.6 4.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.5 0.0 0.2 0.0 13.8 0.1 0.0 0.6 2.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 70.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.7 0.0 0.0 0.9 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 MMRN2 "EMILIN3, EndoGlyx-1, FLJ13465" ENSG00000173269 "Multimerin 2" Q9H8L6 10 86935540-86969481 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Adipocytes: 229.3;Endothelial cells: 127.1;Hepatic stellate cells: 182.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 89.2;HUVEC TERT2: 196.6;TIME: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020741 Approved Vesicles "Secreted to extracellular matrix" NA NA 84000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA020741: AB_1848154" "unprognostic (4.17e-1)" "unprognostic (7.87e-2)" "unprognostic (6.67e-3)" "unprognostic (3.30e-1)" "unprognostic (1.73e-1)" "unprognostic (2.08e-2)" "unprognostic (1.75e-3)" "unprognostic (1.43e-1)" "unprognostic (2.09e-2)" "unprognostic (3.11e-2)" "unprognostic (1.81e-2)" "unprognostic (1.34e-1)" "unprognostic (6.17e-3)" "unprognostic (1.54e-3)" "unprognostic (1.25e-1)" "unprognostic (6.44e-2)" "unprognostic (1.66e-1)" 63.2 13.9 14.0 10.1 12.7 1.5 54.5 11.5 12.5 20.6 11.0 14.2 10.5 28.1 13.8 16.9 22.7 16.6 38.8 11.4 11.9 22.0 8.6 32.1 9.7 13.6 12.4 23.1 10.5 10.6 7.6 73.8 13.7 14.1 8.9 3.0 26.6 28.7 26.8 38.9 13.8 27.3 13.2 34.6 11.9 15.3 15.8 6.5 25.8 32.5 13.3 32.3 19.1 12.0 11.4 2.9 0.4 0.2 1.2 6.3 7.1 4.1 11.1 4.8 6.8 6.4 89.2 0.1 39.5 7.6 11.6 21.9 0.0 5.2 6.4 8.1 0.0 2.3 10.2 0.2 0.9 0.0 4.6 1.5 26.4 5.7 38.6 13.0 196.6 2.4 2.1 35.0 1.8 7.1 0.4 4.4 2.0 0.4 4.9 0.2 0.1 0.1 2.0 17.5 4.8 0.0 3.1 3.7 1.4 0.9 14.9 1.2 237.1 1.9 11.0 1.9 0.1 2.6 4.0 0.1 5.8 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 14.0 12.7 11.5 12.5 11.4 11.9 13.6 12.4 13.7 13.2 15.8 12.0 229.3 0.0 5.8 1.6 0.3 9.4 0.9 0.0 4.6 0.2 1.4 2.0 13.2 5.7 0.7 1.8 0.0 0.7 0.4 0.0 0.0 0.1 1.0 0.3 0.4 127.1 0.0 2.7 0.9 0.0 0.1 8.1 0.0 0.5 0.0 0.2 182.0 4.1 1.7 0.0 1.2 0.0 0.0 6.5 4.4 2.8 2.5 0.7 3.6 15.9 0.0 0.7 0.0 1.0 0.1 0.0 0.0 3.0 0.1 0.6 0.5 0.2 0.0 0.6 6.6 3.9 9.4 1.8 2.3 2.2 7.7 0.3 0.8 3.6 0.2 1.0 MNDA PYHIN3 ENSG00000163563 "Myeloid cell nuclear differentiation antigen" P41218 1 158831351-158849506 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 292.9;lymphoid tissue: 107.8" "Cell type enhanced" "Detected in many" "Hofbauer cells: 219.1;Kupffer cells: 408.5;Langerhans cells: 241.7;Macrophages: 412.0;monocytes: 1118.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "neutrophil: 6012.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 6012.8" "Group enriched" "Detected in some" 14 "NB-4: 151.8;THP-1: 282.7;U-937: 185.5" "Low region specificity" "Detected in all" "HPA034532, HPA073215" Enhanced Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Vesicles,Cytosol" NA NA 400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Nucleoli, Nucleoli rim, Vesicles, Cytosol" "HPA034532: AB_10669677, HPA073215: AB_2686582" "unprognostic (1.53e-2)" "unprognostic (7.84e-3)" "unprognostic (2.45e-2)" "unprognostic (1.03e-1)" "unprognostic (1.42e-1)" "unprognostic (1.41e-2)" "unprognostic (2.02e-2)" "unprognostic (7.99e-3)" "unprognostic (1.58e-2)" "unprognostic (1.46e-1)" "unprognostic (1.65e-1)" "unprognostic (9.89e-2)" "unprognostic (1.96e-2)" "unprognostic (1.07e-1)" "unprognostic (4.95e-2)" "unprognostic (2.81e-2)" "unprognostic (1.02e-1)" 24.2 14.9 2.7 82.4 2.8 292.9 6.0 2.9 4.4 6.3 3.2 6.7 3.7 4.0 1.4 7.4 5.7 26.6 4.3 2.6 3.1 3.6 11.5 47.3 15.6 5.2 4.3 2.2 4.8 3.7 1.6 20.4 4.3 3.8 7.7 12.1 5.7 3.5 3.8 5.1 7.7 20.7 5.1 107.8 4.5 5.1 4.2 14.4 3.8 19.0 14.5 23.4 1.8 5.4 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 14.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 151.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 282.7 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.2 0.0 185.5 0.0 155.4 1354.4 243.8 2.6 534.3 3.7 33.5 1.6 1.9 616.5 15.3 1.6 1.4 6012.8 2.8 270.6 9.6 1.5 1099.5 2.7 2.8 2.9 4.4 2.6 3.1 5.2 4.3 4.3 5.1 4.2 5.4 2.6 35.3 56.0 0.0 34.7 2.4 0.0 0.0 0.0 1.2 1.1 3.4 0.9 5.7 9.3 0.0 0.0 0.9 5.9 0.0 0.0 0.0 0.4 0.1 0.1 5.0 0.0 22.3 0.0 0.4 1.3 6.5 0.5 0.1 44.1 0.0 3.9 2.2 219.1 0.0 0.1 0.0 0.0 408.5 241.7 3.3 1.2 412.0 1.8 33.7 1118.9 136.1 26.8 0.5 0.1 0.0 0.0 0.0 1.1 0.0 0.0 1.7 8.0 4.8 13.1 1.5 8.2 0.9 0.3 0.4 2.3 1.0 11.7 0.0 0.0 0.1 MOSPD1 dJ473B4 ENSG00000101928 "Motile sperm domain containing 1" Q9UJG1 X 134887632-134915257 "Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 106.9;Endometrial ciliated cells: 80.3;Erythroid cells: 150.1;Late spermatids: 82.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031158 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 13: T-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Vesicles" "HPA031158: AB_10603874" "unprognostic (2.23e-3)" "unprognostic (3.37e-3)" "unprognostic (1.34e-1)" "unprognostic (2.30e-1)" "unprognostic (1.77e-1)" "unprognostic (3.36e-1)" "unprognostic (6.78e-3)" "unprognostic (5.15e-2)" "unprognostic (1.58e-1)" "unprognostic (1.25e-1)" "unprognostic (6.20e-3)" "unprognostic (4.27e-2)" "unprognostic (6.45e-3)" "unprognostic (2.92e-2)" "unprognostic (2.01e-1)" "unprognostic (5.71e-2)" "unprognostic (1.15e-1)" 5.1 14.0 4.1 4.9 4.1 15.4 8.3 4.5 5.5 8.7 12.4 6.7 5.9 16.2 12.8 15.2 26.9 7.1 20.0 4.0 4.4 10.9 7.6 7.5 6.2 4.8 4.4 10.9 7.7 15.1 3.4 11.8 4.5 8.4 7.4 6.7 9.4 7.7 21.5 10.4 5.6 11.3 4.4 6.4 5.4 10.4 4.4 9.7 9.6 14.1 8.5 10.6 8.8 4.5 19.6 15.1 12.5 8.7 19.5 11.4 27.3 32.2 58.2 30.4 29.4 37.2 7.6 6.5 43.7 20.6 54.9 6.9 19.6 16.7 39.9 21.9 11.5 5.6 36.7 15.1 82.2 15.6 9.1 20.6 20.0 34.2 14.7 34.5 22.6 13.3 7.0 25.9 37.3 27.2 11.2 7.1 12.8 10.2 34.1 8.3 22.2 12.4 13.0 55.3 7.4 9.2 16.3 16.2 56.7 60.6 6.5 9.7 11.3 14.9 9.2 56.0 29.0 20.1 29.0 10.4 20.2 26.4 19.9 4.9 5.4 10.5 5.8 4.3 7.9 4.7 6.9 6.4 6.3 4.1 7.7 7.6 3.5 5.1 5.1 6.7 12.4 4.1 4.1 4.1 4.5 5.5 4.0 4.4 4.8 4.4 4.5 4.4 4.4 4.5 13.2 6.4 5.8 3.9 11.0 21.3 10.6 13.8 29.6 8.5 10.8 9.4 43.7 4.3 11.8 11.0 2.1 9.0 6.9 7.6 21.5 26.3 106.9 80.3 10.5 12.2 4.2 150.1 7.6 12.4 16.0 10.5 8.6 12.0 5.7 21.5 13.9 6.7 14.9 5.0 8.8 6.9 16.2 11.9 7.7 82.9 6.8 7.5 30.2 4.7 7.4 9.3 11.3 9.0 4.4 20.9 12.7 10.9 14.7 11.8 5.7 27.9 20.0 8.5 6.6 6.8 16.9 3.8 6.6 12.2 20.5 26.1 13.2 15.8 7.1 9.9 MPLKIP "C7orf11, ORF20, TTDN1" ENSG00000168303 "M-phase specific PLK1 interacting protein" Q8TAP9 7 40126027-40134622 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058457, HPA065463" Uncertain Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Golgi apparatus, Vesicles" "HPA058457: AB_2683724, HPA065463: AB_2685493" "unprognostic (5.59e-2)" "unprognostic (1.74e-1)" "unprognostic (9.40e-2)" "unprognostic (2.39e-2)" "unprognostic (5.55e-2)" "unprognostic (1.34e-3)" "unprognostic (2.73e-1)" "unprognostic (3.40e-2)" "unprognostic (3.94e-2)" "unprognostic (1.65e-1)" "unprognostic (3.16e-3)" "unprognostic (8.89e-2)" "unprognostic (1.61e-2)" "unprognostic (8.44e-2)" "unprognostic (2.91e-2)" "unprognostic (1.91e-2)" "unprognostic (6.08e-2)" 2.9 3.8 2.6 2.0 2.6 2.4 2.8 4.7 3.0 2.8 3.0 2.8 2.2 2.6 2.0 3.1 2.5 1.2 2.1 2.6 2.3 4.2 8.0 2.1 2.6 2.4 2.3 2.8 2.9 2.5 3.0 1.8 2.6 2.5 1.8 3.1 2.7 1.5 2.4 3.0 2.6 1.1 2.0 3.1 2.4 2.3 2.5 3.3 3.0 1.4 2.0 2.5 2.7 4.0 8.2 2.5 4.8 6.6 4.3 4.9 4.9 3.1 3.3 4.4 4.3 3.1 4.0 6.8 4.2 3.0 8.7 10.3 3.0 5.3 5.6 5.2 9.2 5.4 3.7 6.9 4.9 6.7 5.2 4.8 6.7 3.4 4.1 4.5 5.1 7.5 13.1 5.5 4.4 4.1 6.8 20.4 6.7 6.7 7.4 9.6 3.3 8.9 5.0 2.1 7.1 8.4 5.0 4.8 7.7 6.2 6.1 9.3 5.5 2.8 7.5 3.6 4.7 8.6 9.6 10.9 4.4 10.5 7.6 20.6 11.2 16.8 8.0 10.8 9.0 16.9 10.1 9.4 11.8 15.3 11.3 9.9 9.2 10.6 10.4 13.1 14.2 13.1 2.6 2.6 4.7 3.0 2.6 2.3 2.4 2.3 2.6 2.0 2.5 4.0 49.8 51.3 34.5 6.5 53.3 110.1 96.2 151.8 58.6 43.5 53.8 66.2 18.0 67.2 79.6 58.8 25.0 110.8 41.3 60.3 117.4 66.6 118.4 73.6 62.3 58.0 48.6 52.2 7.4 54.6 79.7 51.1 35.7 56.6 51.3 63.6 47.2 133.4 69.0 53.8 8.1 63.4 85.5 59.3 62.6 38.6 75.8 50.4 58.7 7.5 74.6 52.9 66.9 12.1 12.5 59.9 97.2 55.3 36.3 76.2 61.6 190.5 91.1 50.1 52.6 57.1 58.4 66.6 53.9 67.1 134.1 95.6 46.8 125.7 82.3 105.7 MPO ENSG00000005381 Myeloperoxidase P05164 17 58269855-58280935 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 61 "bone marrow: 4023.1" "Cell type enriched" "Detected in some" 30 "Erythroid cells: 87.4" "Cancer enhanced" "Detected in single" "stomach cancer: 1.1" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "classical monocyte: 6.2" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 94 "HL-60: 3517.4;NB-4: 4589.9" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000059, HPA021147, HPA061464" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" No NA 576000000 24000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles Nucleoplasm "CAB000059: AB_2335676, HPA021147: AB_1854083, HPA061464: AB_2684531" "unprognostic (1.91e-1)" "unprognostic (9.08e-2)" "unprognostic (4.62e-2)" "unprognostic (2.90e-2)" "unprognostic (2.13e-3)" "unprognostic (2.78e-1)" "unprognostic (3.23e-1)" "unprognostic (2.91e-1)" "unprognostic (2.56e-1)" "unprognostic (1.68e-1)" "unprognostic (6.92e-2)" "unprognostic (8.34e-3)" "unprognostic (4.91e-2)" "unprognostic (3.07e-3)" "unprognostic (2.83e-1)" "unprognostic (1.14e-2)" "unprognostic (8.05e-2)" 0.5 0.4 0.8 0.6 0.6 4023.1 0.3 0.6 1.1 0.0 0.3 0.2 0.0 0.2 1.1 0.1 0.1 0.3 1.1 0.8 0.7 0.2 1.8 8.4 1.7 0.9 1.0 0.1 0.1 0.0 1.5 1.4 0.9 0.2 0.2 0.4 66.3 0.1 1.1 4.3 0.2 0.3 0.8 21.7 0.1 0.4 0.8 10.9 0.3 0.3 0.2 0.5 0.1 0.7 0.4 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 3517.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4589.9 0.0 0.0 0.0 5.3 3.2 0.6 0.0 0.0 0.0 0.5 1.1 0.0 0.0 0.0 0.0 43.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.1 0.0 4.0 0.0 0.0 6.2 0.0 0.0 3.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.4 0.0 0.6 0.0 0.1 7.5 0.8 0.6 0.6 1.1 0.8 0.7 0.9 1.0 0.9 0.8 0.8 0.7 0.0 0.0 0.5 0.7 0.3 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 1.9 0.0 0.5 0.1 0.0 0.1 0.0 87.4 0.3 0.2 0.9 0.7 0.0 0.0 0.0 0.0 0.7 0.3 0.9 0.0 0.2 0.0 0.0 1.2 0.0 1.3 0.0 2.9 0.0 0.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.1 0.1 0.3 0.1 0.0 0.1 0.6 0.0 0.0 0.0 MPPED2 "239FB, C11orf8, D11S302E, dJ1024C24.1, dJ873F21.1, FAM1B, Hs.46638" ENSG00000066382 "Metallophosphoesterase domain containing 2" Q15777 11 30384493-30586872 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 24.5;thyroid gland: 24.6" "Cell type enhanced" "Detected in many" "Astrocytes: 155.7;Cone photoreceptor cells: 285.7;Excitatory neurons: 108.1;Horizontal cells: 82.4;Oligodendrocyte precursor cells: 345.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HaCaT: 21.6;HAP1: 12.2;JURKAT: 10.9;RT4: 9.0;SH-SY5Y: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062575 Approved Nucleoli,Vesicles,Mitochondria NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoli "Vesicles, Mitochondria" "HPA062575: AB_2684797" "unprognostic (9.60e-3)" "unprognostic (6.12e-3)" "unprognostic (3.70e-3)" "unprognostic (4.56e-2)" "unprognostic (5.46e-2)" "unprognostic (5.04e-2)" "unprognostic (1.46e-1)" "unprognostic (2.32e-1)" "unprognostic (1.57e-2)" "unprognostic (1.13e-1)" "unprognostic (7.98e-4)" "unprognostic (6.82e-2)" "unprognostic (2.47e-7)" "unprognostic (3.64e-3)" "unprognostic (2.50e-1)" "unprognostic (2.22e-2)" "unprognostic (2.57e-2)" 2.0 5.2 6.3 0.5 13.3 0.3 4.1 4.7 10.5 24.5 0.9 4.9 0.7 6.4 5.6 0.9 8.9 1.0 3.7 11.9 13.0 9.6 0.4 0.4 0.2 19.6 10.3 0.5 1.6 3.2 11.0 1.6 11.7 12.6 0.6 16.0 10.3 7.4 5.1 0.7 1.0 3.6 4.9 2.3 1.7 1.7 9.5 3.6 24.6 1.5 0.3 3.3 5.1 6.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.6 12.2 0.0 0.0 0.0 2.6 0.0 0.2 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.9 0.0 0.3 3.5 0.1 0.1 0.0 3.4 0.2 0.0 9.0 0.1 6.5 0.0 0.0 3.6 1.3 1.8 0.0 0.1 0.0 1.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 1.8 0.0 0.0 0.2 0.1 0.4 0.5 0.0 0.0 0.7 0.0 0.2 0.0 0.1 6.3 13.3 4.7 10.5 11.9 13.0 19.6 10.3 11.7 4.9 9.5 6.8 3.1 0.0 2.2 155.7 1.8 1.0 51.7 2.6 2.8 26.7 3.6 5.2 5.2 0.0 1.0 46.0 285.7 0.3 0.5 0.1 25.4 4.2 2.1 35.6 1.5 6.3 0.0 1.3 108.1 0.0 0.2 2.6 0.0 13.8 5.1 12.1 0.7 0.2 4.1 82.4 56.0 0.3 2.0 22.5 3.6 1.6 0.3 2.7 5.4 13.1 0.5 44.0 0.0 345.8 7.9 0.1 0.1 3.4 0.5 19.3 0.0 3.1 3.0 18.5 0.0 1.2 7.1 0.1 2.1 1.5 1.1 0.5 0.8 0.4 0.0 28.4 MPV17L "FLJ39599, MLPH1, MLPH2, MPV17L1" ENSG00000156968 "MPV17 mitochondrial inner membrane protein like" Q2QL34 16 15395754-15413271 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 14.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 29.5;SK-BR-3: 8.2" "Low region specificity" "Detected in all" HPA041180 Approved Supported Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA041180: AB_10794266" "unprognostic (9.65e-2)" "unprognostic (8.74e-2)" "unprognostic (4.16e-1)" "unprognostic (1.35e-3)" "unprognostic (6.68e-2)" "unprognostic (2.84e-1)" "unprognostic (2.73e-1)" "unprognostic (4.38e-3)" "unprognostic (8.41e-2)" "unprognostic (8.99e-3)" "unprognostic (8.70e-2)" "unprognostic (6.36e-3)" "prognostic favorable (1.48e-11)" "unprognostic (2.84e-1)" "unprognostic (7.60e-2)" "unprognostic (6.61e-3)" "unprognostic (3.87e-2)" 1.8 2.5 1.2 1.8 0.1 4.4 6.4 1.9 2.2 2.8 0.0 2.3 3.4 2.0 0.3 1.0 1.8 2.4 1.6 0.1 0.0 3.3 9.1 0.9 2.3 0.1 0.0 2.1 14.1 2.4 3.2 0.6 0.3 2.0 1.0 4.4 7.1 1.8 8.0 4.5 2.3 0.8 0.0 1.8 1.8 1.0 0.5 0.2 2.2 2.4 0.6 1.9 1.3 0.4 1.0 1.9 0.8 0.8 0.2 0.1 1.2 0.5 0.0 0.0 0.0 1.9 3.4 1.5 1.3 0.6 0.5 1.5 3.0 0.0 0.0 1.2 0.8 5.9 4.6 3.9 0.3 3.6 29.5 0.3 0.4 0.1 0.2 0.5 0.0 1.6 2.3 3.3 0.1 1.9 1.4 2.3 1.7 0.3 0.1 2.0 0.6 1.6 0.5 0.8 4.8 1.6 2.7 8.2 0.2 0.9 1.8 2.6 2.6 1.3 0.8 1.1 1.1 1.4 0.6 1.7 0.7 1.7 0.5 1.7 1.2 0.2 0.8 0.9 0.6 0.8 0.5 0.8 0.4 1.2 0.4 0.8 1.8 1.1 0.4 0.7 0.4 0.6 1.2 0.1 1.9 2.2 0.1 0.0 0.1 0.0 0.3 0.0 0.5 0.4 2.5 6.4 8.8 3.9 2.0 7.9 14.4 8.2 0.0 12.8 11.4 6.0 6.0 14.3 13.1 0.0 10.4 0.5 4.1 2.7 15.6 7.5 4.6 5.4 9.2 6.6 1.2 2.1 5.6 12.9 0.5 8.1 2.0 10.7 6.3 7.6 4.2 29.1 1.0 8.4 5.9 8.7 2.0 13.6 20.6 0.8 7.2 6.0 21.4 2.8 0.7 6.2 0.0 7.5 3.2 5.9 15.3 14.3 1.4 9.6 9.3 19.9 21.0 16.6 0.0 23.5 6.7 9.0 2.0 0.6 11.5 0.5 9.9 4.4 12.1 10.1 MPZL1 "FLJ21047, PZR" ENSG00000197965 "Myelin protein zero like 1" O95297 1 167721192-167791919 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 183.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 183.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026966, HPA063538" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA026966: AB_10600931, HPA063538: AB_2685034" "unprognostic (6.54e-2)" "unprognostic (9.26e-3)" "unprognostic (4.59e-2)" "unprognostic (4.88e-1)" "unprognostic (2.18e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (4.27e-6)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.22e-1)" "unprognostic (3.41e-2)" "unprognostic (2.59e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (3.99e-7)" "unprognostic (3.55e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (8.08e-4)" "unprognostic (4.21e-2)" 74.8 34.1 23.1 49.2 21.6 8.3 91.6 22.0 21.8 63.1 40.1 60.1 40.8 50.0 27.4 52.9 60.1 67.7 52.4 22.1 28.3 28.6 23.0 42.3 35.2 25.7 30.0 46.4 27.5 28.4 33.0 68.9 30.7 41.8 59.4 12.7 73.1 38.9 14.7 34.0 41.0 62.6 26.4 29.2 43.8 48.2 28.6 29.3 39.5 26.8 45.9 74.7 51.3 24.9 88.5 126.3 96.9 75.8 303.4 137.2 304.8 134.5 172.7 86.3 106.4 234.4 119.5 31.0 152.9 171.6 76.1 144.2 97.5 149.0 72.6 70.9 52.8 25.5 63.5 56.7 188.5 30.2 16.1 126.1 183.5 137.8 153.4 121.4 116.4 93.6 97.1 63.5 103.0 29.3 103.6 36.2 61.9 176.7 53.5 62.5 82.7 137.5 131.4 84.6 55.7 91.8 119.6 122.4 69.7 221.9 66.6 16.0 132.8 97.9 44.1 127.5 73.8 94.0 157.2 142.8 140.8 35.3 15.8 7.7 29.1 20.0 2.8 24.8 1.3 14.7 2.8 4.1 38.5 8.8 7.7 2.6 183.8 10.4 34.6 43.9 0.5 11.0 23.1 21.6 22.0 21.8 22.1 28.3 25.7 30.0 30.7 26.4 28.6 24.9 52.9 28.9 30.0 31.0 15.1 76.3 78.5 57.6 35.9 8.8 75.9 73.9 6.3 20.0 49.6 20.2 6.2 128.7 21.1 67.1 5.9 63.2 1.8 14.5 40.4 56.7 47.8 10.1 32.8 75.6 145.2 118.2 41.3 23.0 3.8 75.3 24.3 23.3 37.7 10.1 27.9 39.7 20.3 28.2 31.9 4.9 69.9 23.5 16.0 60.0 84.0 11.8 3.1 141.8 1.7 81.0 41.6 83.8 23.5 141.7 55.5 10.1 28.3 13.9 19.7 18.6 48.6 8.9 26.8 41.2 55.5 76.9 8.6 49.4 61.0 57.7 MRAP "B27, C21orf61, FALP" ENSG00000170262 "Melanocortin 2 receptor accessory protein" Q8TCY5 21 32291813-32314784 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 27 "adipose tissue: 75.6;adrenal gland: 166.5;breast: 44.2" "Group enriched" "Detected in some" 5 "Early spermatids: 16.1;Granulosa cells: 43.7;Horizontal cells: 43.7" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "NK-cell: 1.9" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 5 "Hep G2: 1.5;HSkMC: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011024, HPA011093" Uncertain Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" Vesicles "HPA011024: AB_10599292, HPA011093: AB_10600889" "unprognostic (1.38e-1)" "unprognostic (1.55e-3)" "unprognostic (1.53e-1)" "unprognostic (1.11e-1)" "unprognostic (9.53e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" "unprognostic (2.27e-1)" "unprognostic (1.18e-1)" "unprognostic (1.80e-2)" "unprognostic (4.12e-1)" "unprognostic (6.30e-6)" "unprognostic (3.32e-2)" "unprognostic (2.37e-1)" "unprognostic (1.18e-1)" "unprognostic (5.76e-2)" 75.6 166.5 0.1 1.8 0.1 0.0 44.2 0.0 0.5 0.1 0.8 1.2 0.2 0.0 0.0 0.1 0.0 0.6 2.0 0.1 0.0 0.3 2.4 1.0 0.1 0.2 0.0 2.0 0.7 0.0 0.1 1.7 0.1 0.0 0.2 1.0 2.0 0.0 0.2 1.3 3.5 0.1 0.0 0.0 0.6 0.5 0.0 0.1 0.7 0.2 0.0 1.4 0.4 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.2 0.7 0.2 0.4 0.2 0.8 0.2 0.5 0.0 1.9 0.1 0.5 0.7 0.0 0.1 0.1 0.0 0.5 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 1.1 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.1 0.4 0.0 0.1 0.0 0.0 0.7 0.0 0.1 1.3 0.0 0.0 0.0 43.7 0.0 1.7 0.1 43.7 0.6 0.0 0.0 0.0 0.0 6.6 0.6 0.1 0.0 0.0 0.0 0.3 0.0 2.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.6 1.6 0.1 0.0 0.0 0.0 0.0 1.9 0.0 0.0 MRAS "M-RAs, R-RAS3, RRAS3" ENSG00000158186 "Muscle RAS oncogene homolog" O14807 3 138347648-138405534 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 202.3;heart muscle: 132.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 121.7;Distal tubular cells: 58.7;Theca cells: 59.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "non-classical monocyte: 25.0" "Lineage enriched" "Detected in many" 9 "monocytes: 25.0" "Cell line enhanced" "Detected in many" "BJ: 92.9;EFO-21: 113.7;fHDF/TERT166: 70.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042728 Approved Approved Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 38: EFO-21 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol Vesicles "HPA042728: AB_10796582" "unprognostic (1.96e-1)" "unprognostic (2.95e-1)" "unprognostic (1.63e-3)" "prognostic unfavorable (1.73e-4)" "unprognostic (1.69e-1)" "unprognostic (5.32e-2)" "unprognostic (8.96e-2)" "unprognostic (3.85e-3)" "unprognostic (1.70e-1)" "unprognostic (1.86e-1)" "unprognostic (1.71e-1)" "unprognostic (2.59e-1)" "unprognostic (3.18e-3)" "unprognostic (1.78e-2)" "unprognostic (6.25e-2)" "unprognostic (2.21e-1)" "unprognostic (4.23e-2)" 91.9 67.7 112.7 10.8 130.6 1.7 46.7 118.2 105.5 17.3 48.9 24.2 3.3 28.7 7.1 7.9 26.4 12.0 132.9 105.6 132.8 22.9 5.5 18.4 5.2 126.1 135.9 48.6 5.7 8.2 17.7 10.6 112.9 15.3 4.1 15.9 13.4 15.0 80.4 12.2 8.7 23.2 110.3 12.2 12.0 9.6 202.3 4.9 26.4 48.0 3.3 29.1 12.1 97.8 0.8 7.9 15.8 24.5 59.6 29.2 40.0 92.9 16.0 7.3 8.2 3.3 3.1 0.3 113.7 70.4 18.6 0.1 9.0 1.8 6.1 7.7 3.1 0.5 4.8 20.1 15.9 0.0 1.9 41.5 5.9 0.7 1.4 13.6 1.3 0.0 10.7 0.8 31.4 3.7 0.0 20.4 19.1 0.0 2.7 1.1 33.8 0.2 30.4 2.0 18.6 42.0 62.8 0.7 45.9 10.9 16.1 37.7 0.6 23.7 25.3 24.3 2.4 0.1 1.0 1.2 21.4 0.1 11.4 0.2 2.1 0.0 0.0 4.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.3 0.8 25.0 0.1 0.0 0.8 112.7 130.6 118.2 105.5 105.6 132.8 126.1 135.9 112.9 110.3 202.3 97.8 8.9 9.6 1.5 54.2 0.8 2.2 3.0 3.4 1.2 5.6 28.8 34.8 121.7 2.8 3.5 9.2 10.4 20.1 0.2 0.0 58.7 8.6 11.6 1.0 21.4 14.5 1.8 0.0 25.5 3.2 3.2 23.0 2.0 1.5 6.3 35.2 12.8 1.6 26.3 28.6 20.6 0.0 2.0 15.1 18.4 40.0 23.3 18.2 28.4 20.6 12.2 24.3 0.0 28.6 11.0 3.8 0.0 34.3 0.1 3.3 0.0 27.5 1.3 9.6 6.6 20.8 18.9 7.3 18.6 0.4 1.0 14.4 0.8 59.1 0.0 0.6 MREG "DSU, FLJ10116, WDT2" ENSG00000118242 Melanoregulin Q8N565 2 215942584-216034096 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 46.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 60.5;Glandular and luminal cells: 34.1;Rod photoreceptor cells: 40.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 82.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068583 Approved Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" Vesicles "HPA068583: AB_2686009" "unprognostic (4.53e-2)" "unprognostic (1.12e-1)" "unprognostic (3.05e-1)" "unprognostic (1.20e-2)" "unprognostic (3.24e-1)" "unprognostic (1.13e-2)" "unprognostic (3.70e-1)" "unprognostic (7.37e-2)" "unprognostic (2.39e-1)" "unprognostic (5.85e-3)" "unprognostic (8.11e-3)" "unprognostic (8.93e-2)" "unprognostic (6.38e-3)" "unprognostic (6.62e-3)" "unprognostic (6.92e-2)" "prognostic favorable (4.20e-4)" "unprognostic (9.99e-2)" 5.9 8.2 3.9 5.4 8.9 5.9 21.4 17.9 5.6 6.7 6.2 5.6 6.4 3.4 5.0 29.8 5.8 2.8 0.7 4.6 4.5 5.4 17.8 10.3 10.8 5.6 4.7 2.5 2.2 7.3 7.6 7.7 5.9 2.4 5.8 46.9 4.9 6.1 2.7 20.2 5.5 1.8 3.3 4.4 6.8 1.1 6.5 9.9 6.6 0.9 15.1 5.5 14.3 5.0 20.9 5.1 5.9 3.5 3.9 2.1 13.1 7.0 5.6 4.6 8.9 24.3 15.5 6.7 6.0 4.3 11.5 13.0 17.9 26.5 10.1 14.1 15.1 10.6 5.6 43.5 2.3 6.0 3.9 3.9 11.2 5.3 7.4 4.6 4.0 15.2 5.3 17.8 2.9 82.8 17.0 5.7 23.3 12.4 4.8 9.8 13.9 10.7 12.3 29.3 16.4 8.6 4.4 36.4 40.3 13.7 20.2 2.8 0.5 9.8 2.5 5.0 10.7 23.0 15.3 17.5 6.0 22.2 7.5 1.6 0.1 0.2 0.7 0.1 1.2 1.1 0.6 1.1 0.1 0.6 0.3 0.5 0.8 0.8 0.2 2.1 1.0 0.1 3.9 8.9 17.9 5.6 4.6 4.5 5.6 4.7 5.9 3.3 6.5 5.0 0.6 3.2 13.4 7.8 4.3 2.7 12.1 0.6 9.6 14.4 24.1 12.1 0.8 2.8 9.2 7.3 60.5 21.7 8.5 3.8 3.9 3.2 0.3 14.0 1.9 1.1 1.8 2.1 21.1 2.5 4.7 1.8 5.6 34.1 1.3 0.6 1.4 8.3 13.4 1.7 21.4 1.8 2.0 0.8 3.0 0.0 2.5 4.0 5.4 6.5 21.3 7.6 2.1 8.5 12.8 7.5 4.6 7.5 7.0 7.0 3.1 1.1 3.0 40.1 6.6 1.2 1.2 1.1 4.6 28.7 1.6 25.9 4.0 1.0 2.9 22.6 MS4A6A "CD20L3, MS4A6" ENSG00000110077 "Membrane spanning 4-domains A6A" Q9H2W1 11 60172014-60184666 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 580.8;Hofbauer cells: 376.8;Kupffer cells: 1649.6;Langerhans cells: 470.0;Macrophages: 675.9;monocytes: 429.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 406.4;classical monocyte: 1095.3;intermediate monocyte: 345.6;myeloid DC: 638.8;plasmacytoid DC: 454.4" "Group enriched" "Detected in all" 74 "dendritic cells: 638.8;granulocytes: 406.4;monocytes: 1095.3" "Cell line enriched" "Detected in some" 8 "THP-1: 47.9" "HPA011391, HPA076623" Approved Approved Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA011391: AB_10603876, HPA076623: AB_2686809" "unprognostic (1.17e-1)" "prognostic favorable (6.33e-4)" "unprognostic (2.35e-2)" "unprognostic (1.21e-2)" "unprognostic (1.00e-1)" "unprognostic (8.51e-2)" "unprognostic (2.33e-1)" "unprognostic (3.75e-2)" "unprognostic (3.61e-1)" "unprognostic (1.76e-1)" "unprognostic (1.91e-1)" "unprognostic (3.20e-1)" "unprognostic (4.75e-3)" "unprognostic (1.06e-1)" "unprognostic (4.66e-2)" "unprognostic (3.94e-2)" "unprognostic (2.97e-2)" 72.6 42.3 10.7 57.5 10.9 33.5 40.0 10.8 22.5 28.1 14.7 41.0 27.8 14.3 9.6 25.7 16.8 61.4 22.8 10.0 11.8 11.5 108.6 56.4 109.1 15.8 13.7 12.3 7.8 8.7 9.8 65.2 14.8 12.4 54.9 1.4 16.0 18.3 5.3 7.3 45.1 52.6 12.4 121.5 24.5 7.8 13.6 32.2 10.0 17.7 47.6 59.9 8.6 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 4.1 0.0 5.7 0.0 0.0 0.0 0.0 4.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 47.9 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 4.1 0.0 406.4 1095.3 8.2 1.6 345.6 3.4 9.6 2.2 1.4 638.8 1.5 1.0 1.0 72.8 2.1 24.4 454.4 1.9 752.8 10.7 10.9 10.8 22.5 10.0 11.8 15.8 13.7 14.8 12.4 13.6 17.6 5.3 6.4 22.9 0.0 16.1 9.3 0.6 0.0 1.2 0.3 2.2 8.0 3.3 17.2 2.5 3.7 0.0 2.0 220.6 0.3 0.0 0.0 2.2 0.4 0.2 12.8 0.0 43.9 0.1 0.0 2.7 4.3 2.6 0.2 13.9 0.1 580.8 20.5 376.8 0.0 0.1 0.1 0.0 1649.6 470.0 5.1 1.5 675.9 14.2 40.3 429.2 0.0 11.3 0.5 0.1 0.0 1.2 0.0 2.0 0.2 0.0 0.5 1.5 0.6 46.0 3.0 4.4 0.5 1.1 2.4 8.0 2.1 10.4 0.1 0.2 0.3 MS4A6E ENSG00000166926 "Membrane spanning 4-domains A6E" Q96DS6 11 60334831-60396596 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 35.6" "Cell type enriched" "Detected in some" 10 "Early spermatids: 1211.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA076623 Approved Vesicles NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA076623: AB_2686809" "unprognostic (2.58e-1)" "unprognostic (3.35e-1)" "unprognostic (3.47e-1)" "unprognostic (6.81e-3)" "unprognostic (4.55e-4)" "unprognostic (1.08e-1)" "unprognostic (1.71e-1)" "unprognostic (1.76e-1)" 2.1 0.0 0.0 1.1 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 35.6 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1211.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 114.8 6.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 MSH2 "COCA1, HNPCC, HNPCC1" ENSG00000095002 "MutS homolog 2" P43246 2 47403067-47663146 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "testis cancer: 46.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009572, HPA066845, CAB070867" Approved Supported Nucleoplasm,Vesicles NA Yes 28000 "Cluster 48: NK-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm Vesicles "CAB009572: AB_2144828, CAB070867: , HPA066845: AB_2732752" "unprognostic (2.35e-1)" "unprognostic (1.54e-2)" "unprognostic (2.89e-3)" "prognostic unfavorable (4.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.31e-3)" "prognostic unfavorable (1.72e-9)" "unprognostic (1.77e-1)" "unprognostic (7.09e-3)" "unprognostic (8.57e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (5.38e-2)" "unprognostic (3.29e-3)" "unprognostic (1.20e-3)" "unprognostic (5.74e-1)" "unprognostic (8.46e-2)" "unprognostic (1.48e-1)" 8.1 7.5 8.3 12.8 10.5 15.7 15.7 14.6 10.6 9.7 12.2 11.9 7.8 11.7 14.0 9.5 12.4 5.8 10.1 9.6 9.0 8.2 6.7 8.1 23.7 8.6 8.0 8.7 6.5 14.8 6.2 11.6 9.5 8.6 15.0 34.9 8.5 7.7 7.1 11.1 9.3 8.8 8.5 10.8 8.1 16.2 7.9 32.6 15.8 7.2 25.0 7.9 6.4 8.9 114.3 35.3 103.3 57.9 7.3 21.2 64.3 62.9 33.3 80.9 76.9 72.3 50.1 141.2 84.6 23.8 56.6 49.8 78.6 37.4 122.3 68.1 55.8 99.3 42.3 65.6 7.7 97.7 34.9 12.3 11.2 68.1 19.0 19.1 45.2 3.9 165.1 34.0 63.1 44.2 119.6 75.4 195.7 69.3 45.1 151.1 182.2 84.4 35.8 57.3 85.9 91.6 58.4 49.2 48.0 83.6 46.9 38.8 18.7 55.5 70.9 57.1 74.6 20.8 63.4 180.1 33.1 72.5 35.4 3.0 1.3 4.9 8.0 4.4 9.3 6.7 7.7 10.3 2.5 7.9 12.6 13.1 1.0 14.2 3.9 3.4 11.8 6.5 8.3 10.5 14.6 10.6 9.6 9.0 8.6 8.0 9.5 8.5 7.9 8.9 14.7 9.6 11.5 18.6 13.0 8.3 7.9 14.4 8.6 17.4 7.5 7.1 15.6 5.7 12.6 9.2 45.9 19.9 14.2 6.6 3.9 11.5 17.8 21.0 11.3 13.4 3.5 54.1 59.9 8.4 20.7 12.2 7.1 18.8 12.0 28.2 5.0 1.6 11.4 11.8 58.0 12.1 14.2 4.1 4.6 22.8 5.3 5.1 8.8 16.9 5.5 22.6 17.5 35.7 54.7 7.3 5.0 6.4 12.4 2.8 5.4 4.5 23.3 41.1 0.0 9.8 9.0 56.5 50.8 9.3 6.5 5.1 12.8 24.3 13.5 3.8 MSH5 G7 ENSG00000204410 "MutS homolog 5" O43196 6 31739677-31762676 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Meiosis" DNA-binding "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 14.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 18.8;Erythroid cells: 8.0;Gastric mucus-secreting cells: 10.7;Plasma cells: 10.7;Spermatocytes: 10.9;Spermatogonia: 8.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 2.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 3.1;NB-4: 5.2" HPA062688 Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 24: NB-4 - Immune response" "Cluster 59: Non-specific - Transcription" Vesicles "Endoplasmic reticulum" "HPA062688: AB_2684835" "unprognostic (3.21e-3)" "unprognostic (2.32e-2)" "unprognostic (2.05e-1)" "unprognostic (4.37e-2)" "unprognostic (4.51e-1)" "unprognostic (9.20e-4)" "unprognostic (7.67e-3)" "unprognostic (2.57e-2)" "unprognostic (1.45e-2)" "unprognostic (2.05e-3)" "unprognostic (4.59e-3)" "unprognostic (2.28e-2)" "unprognostic (5.19e-5)" "unprognostic (3.75e-2)" "unprognostic (8.83e-2)" "unprognostic (9.21e-2)" "unprognostic (9.34e-4)" 1.3 1.2 0.1 0.5 0.1 0.7 1.5 0.1 0.4 1.7 0.2 1.6 0.0 1.4 0.0 2.2 1.9 0.0 1.0 0.1 0.1 5.6 2.0 1.4 0.6 0.1 0.2 2.3 1.6 0.0 2.2 0.0 0.1 2.9 0.0 0.1 1.6 0.0 0.6 1.8 1.8 0.0 0.1 2.4 1.6 14.0 0.1 0.0 1.5 0.0 0.0 1.6 1.7 0.2 0.3 1.1 0.4 0.9 0.0 0.1 0.0 0.2 0.0 0.4 0.1 0.1 1.0 3.1 0.4 0.0 0.1 0.8 0.0 0.0 0.1 0.0 0.7 1.1 0.1 0.6 0.0 0.3 1.3 0.0 0.0 0.1 0.3 0.5 0.9 1.2 1.9 1.6 0.0 2.1 0.5 5.2 0.9 0.9 0.0 2.1 0.1 2.4 0.3 0.5 0.2 0.8 0.3 0.2 0.0 0.0 0.3 1.8 0.0 0.3 1.6 0.1 0.6 0.3 2.1 1.7 0.0 0.5 0.8 2.5 0.4 0.0 0.4 0.3 0.0 1.4 0.4 0.1 0.1 0.6 0.1 0.1 0.6 0.1 0.6 0.8 0.1 0.1 0.1 0.1 0.1 0.4 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.2 0.4 0.0 2.3 0.0 3.6 0.5 0.5 0.3 3.4 0.7 0.5 0.5 0.3 2.8 0.8 3.7 18.8 0.6 0.5 1.0 0.0 0.2 0.1 1.6 1.3 0.6 1.2 8.0 0.0 0.2 0.4 0.9 10.7 2.8 3.8 3.1 0.4 0.3 0.5 0.0 0.0 1.2 0.0 0.8 1.3 0.5 1.2 1.5 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.4 0.5 0.7 10.7 0.5 2.0 0.8 0.9 7.3 0.0 1.0 1.4 10.9 8.3 6.2 0.4 0.5 2.5 0.9 1.9 0.4 MSH6 GTBP ENSG00000116062 "MutS homolog 6" P52701 2 47695530-47810063 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 119.6;Theca cells: 114.9" "Cancer enhanced" "Detected in all" "testis cancer: 31.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009091, HPA028376, HPA028446, CAB070870" Enhanced Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA Yes 15000 "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Golgi apparatus, Vesicles" "CAB009091: AB_670083, CAB070870: AB_2144959, HPA028376: AB_10598909, HPA028446: AB_10602182" "unprognostic (5.10e-2)" "unprognostic (5.87e-3)" "unprognostic (3.29e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (1.98e-1)" "unprognostic (3.09e-2)" "prognostic unfavorable (7.86e-4)" "unprognostic (1.79e-1)" "unprognostic (2.35e-3)" "unprognostic (1.01e-1)" "unprognostic (1.74e-3)" "unprognostic (8.99e-2)" "prognostic unfavorable (1.06e-7)" "unprognostic (1.22e-1)" "unprognostic (2.31e-1)" "unprognostic (9.68e-2)" "unprognostic (3.48e-2)" 11.7 22.7 9.3 17.7 13.7 24.0 16.2 15.0 12.7 15.5 12.7 13.0 9.0 27.7 10.2 11.7 17.8 10.9 9.3 8.9 11.5 12.1 19.8 11.6 28.4 12.7 11.7 53.0 31.3 17.0 9.8 20.3 13.0 15.0 12.4 21.6 10.8 15.6 10.5 13.1 9.8 27.2 10.7 12.7 10.9 35.3 11.3 36.3 17.2 11.2 31.0 12.8 12.2 19.9 116.5 77.6 128.4 37.5 42.3 46.3 67.9 63.6 51.1 60.2 59.8 67.2 41.4 158.1 84.5 59.5 82.0 46.0 130.3 74.3 82.1 80.7 69.0 117.0 60.8 71.1 28.8 131.5 37.8 38.6 28.3 60.7 41.6 53.8 40.8 5.3 115.9 69.8 61.8 85.5 144.2 80.1 130.7 81.3 37.7 219.6 204.3 84.7 44.5 76.2 92.8 100.3 79.1 40.4 42.7 124.3 54.6 42.6 33.4 72.2 92.3 54.6 80.6 63.8 79.3 276.2 61.9 77.9 42.4 7.7 3.7 3.8 4.8 6.2 5.5 4.3 5.5 5.0 5.5 4.2 8.4 4.5 2.5 5.9 6.4 2.7 5.3 3.6 9.3 13.7 15.0 12.7 8.9 11.5 12.7 11.7 13.0 10.7 11.3 19.9 19.8 28.9 21.4 5.9 19.2 25.2 22.0 12.3 31.9 25.4 14.4 15.1 8.6 2.8 21.8 7.3 35.5 35.6 20.7 7.4 3.9 15.7 46.4 27.1 31.1 18.4 4.8 47.1 8.5 9.6 21.8 24.0 8.6 31.7 17.7 119.6 13.6 10.2 13.0 15.2 12.1 9.7 20.3 5.6 13.2 17.5 25.4 16.8 3.6 7.5 10.0 22.7 8.2 9.5 27.4 9.1 3.7 22.6 31.1 16.1 2.6 6.7 22.1 31.4 6.6 27.4 33.0 54.3 48.8 22.0 17.5 9.6 19.8 114.9 12.1 11.7 MSLN "CAK1, MPF" ENSG00000102854 Mesothelin Q13421 16 760734-768865 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 93.4;fallopian tube: 278.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 189.1;Alveolar cells type 2: 85.6;Club cells: 121.9;Glandular and luminal cells: 57.1;Paneth cells: 214.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 343.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "myeloid DC: 5.9" "Group enriched" "Detected in many" 39 "dendritic cells: 5.9;monocytes: 1.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 513.4;EFO-21: 77.4;HeLa: 173.4;hTCEpi: 111.5;OE19: 96.4" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 9 "spinal cord: 1.7" "CAB002216, HPA017172" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 17000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles Nucleoplasm "CAB002216: AB_563874, HPA017172: AB_1853819" "unprognostic (1.73e-1)" "unprognostic (1.77e-1)" "unprognostic (2.06e-2)" "unprognostic (1.33e-1)" "unprognostic (3.43e-2)" "unprognostic (3.95e-2)" "unprognostic (2.46e-1)" "unprognostic (9.47e-2)" "unprognostic (8.57e-2)" "unprognostic (4.69e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (2.63e-1)" "prognostic favorable (5.91e-4)" "unprognostic (2.00e-2)" "unprognostic (1.60e-1)" "unprognostic (2.14e-2)" "unprognostic (3.35e-2)" 93.4 0.2 0.7 1.1 1.0 3.2 0.5 0.6 1.5 15.9 0.3 8.9 7.1 6.2 24.1 7.1 278.2 16.4 8.4 0.7 0.8 6.5 0.2 71.8 0.2 1.9 1.2 3.7 0.9 0.1 0.7 2.7 1.3 3.8 4.0 0.7 39.3 9.9 0.0 1.4 2.9 3.4 1.0 0.4 13.0 1.1 1.2 0.8 0.2 0.0 27.2 2.9 2.9 1.0 0.4 2.1 0.0 1.0 0.0 0.0 2.3 0.3 7.7 8.7 2.0 7.4 513.4 0.0 77.4 0.7 0.1 1.3 0.0 0.7 0.7 0.2 0.3 0.0 173.4 5.9 4.4 0.2 0.1 0.0 111.5 0.0 2.0 7.8 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.1 0.6 96.4 0.8 0.2 0.2 0.6 2.4 0.1 0.1 0.0 29.7 0.1 0.0 0.1 0.7 0.0 0.0 0.4 12.1 0.1 0.0 0.3 0.3 0.4 0.0 0.0 0.6 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.3 0.7 1.0 0.6 1.5 0.7 0.8 1.9 1.2 1.3 1.0 1.2 1.0 0.0 189.1 85.6 0.0 0.0 0.3 3.0 49.0 0.0 1.4 0.3 0.3 1.6 52.9 121.9 25.8 0.0 0.2 0.0 4.1 0.0 9.3 1.6 35.8 3.3 0.7 3.0 0.0 0.0 0.9 0.0 4.6 0.0 57.1 0.0 0.0 0.4 0.1 2.9 0.0 0.0 1.6 22.4 1.0 1.9 7.4 4.7 3.7 1.8 1.0 4.4 0.0 0.0 0.0 0.0 33.0 214.4 0.0 1.4 3.3 1.7 0.1 54.2 0.6 0.0 0.0 2.8 0.6 0.7 0.5 0.1 0.1 1.3 0.0 3.1 50.8 MSMP "PC-3, PSMP" ENSG00000215183 "Microseminoprotein, prostate associated" Q1L6U9 9 35752990-35756613 "Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.5;choroid plexus: 1.1;pituitary gland: 1.5;placenta: 1.2" "Group enriched" "Detected in some" 50 "Early spermatids: 96.3;Late spermatids: 216.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HUVEC TERT2: 85.7;PC-3: 108.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA055174 Uncertain Supported Vesicles,Cytosol "Secreted in other tissues" No No 30000 "Cluster 10: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 34: Spermatids - Unknown function" Vesicles Cytosol "HPA055174: AB_2682726" 0.2 0.0 0.6 0.2 0.3 0.0 0.1 0.4 0.8 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.1 0.0 0.1 0.2 1.5 0.4 0.0 0.0 0.0 1.5 1.2 0.9 0.0 0.1 0.2 0.0 0.0 0.5 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.3 0.0 0.2 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 85.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.1 0.1 0.6 0.3 0.4 0.8 0.3 0.3 1.5 0.4 0.9 0.6 0.3 0.4 1.3 0.0 1.1 0.0 1.1 0.4 1.0 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.0 1.4 96.3 0.6 0.1 3.1 0.0 0.0 0.0 2.0 0.2 0.3 0.0 0.2 0.0 0.5 2.5 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.8 216.6 0.3 0.1 1.8 0.0 0.0 0.4 0.0 0.0 0.0 1.8 0.1 0.7 0.1 1.5 0.0 0.4 0.2 0.5 0.0 0.0 0.1 0.8 0.5 0.0 0.1 0.3 0.2 0.1 0.3 1.3 MSS51 "FLJ39565, ZMYND17" ENSG00000166343 "MSS51 mitochondrial translational activator" Q4VC12 10 73423579-73433561 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 261.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 5.3;Excitatory neurons: 11.9;Inhibitory neurons: 9.7;Oligodendrocyte precursor cells: 6.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA038564 Uncertain Vesicles,Cytosol NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" Vesicles Cytosol "HPA038564: AB_10674687" "unprognostic (2.49e-2)" "unprognostic (2.07e-1)" "unprognostic (1.40e-3)" "unprognostic (2.06e-1)" "unprognostic (3.21e-2)" "unprognostic (1.62e-3)" "unprognostic (3.05e-3)" "unprognostic (7.88e-3)" "unprognostic (1.98e-2)" "unprognostic (3.78e-2)" "unprognostic (1.50e-4)" "unprognostic (1.22e-1)" "unprognostic (1.78e-7)" "unprognostic (1.51e-1)" "unprognostic (2.60e-1)" "unprognostic (2.67e-1)" "unprognostic (1.55e-2)" 1.9 1.5 1.5 1.5 1.8 1.6 1.7 4.3 2.0 3.2 1.6 2.3 1.2 2.1 1.7 1.4 2.2 1.2 10.9 1.5 0.6 1.7 1.6 2.2 1.8 0.2 0.3 3.0 1.9 56.2 2.3 0.6 0.2 2.5 1.3 2.5 1.7 0.8 261.3 3.7 2.7 1.1 0.0 3.9 1.8 1.4 0.7 1.5 1.5 5.9 1.5 2.2 2.2 1.3 0.9 0.6 1.5 2.7 2.1 2.8 1.2 0.7 0.5 0.3 0.6 0.3 0.7 2.1 0.2 0.7 0.1 1.1 1.0 0.2 0.8 1.1 0.9 1.7 1.3 0.5 0.7 1.1 1.7 2.4 0.7 0.6 1.7 2.1 0.2 0.8 0.6 1.0 1.2 0.2 0.9 1.6 0.4 0.5 0.7 0.5 4.1 0.1 0.8 0.9 0.3 0.8 0.5 1.0 0.9 1.4 0.9 0.9 1.3 1.2 0.7 0.4 1.7 0.6 2.1 1.1 0.5 1.9 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.8 4.3 2.0 1.5 0.6 0.2 0.3 0.2 0.0 0.7 1.3 0.9 0.0 3.6 4.6 1.0 0.5 0.1 0.6 0.0 1.4 0.4 0.5 5.3 0.0 0.2 0.0 0.0 0.3 0.4 0.4 0.0 0.4 0.3 0.4 0.7 1.2 0.0 1.3 11.9 0.4 0.2 0.8 1.1 0.8 5.1 1.8 1.4 0.2 0.2 0.0 9.7 0.4 0.0 0.8 0.6 0.3 3.1 0.5 0.0 4.7 1.1 0.5 1.0 6.0 3.4 0.2 3.9 1.5 0.4 0.5 0.6 0.2 0.3 1.2 0.0 4.0 0.6 0.7 0.3 0.0 0.0 0.1 1.1 1.4 0.6 0.2 MTA3 KIAA1266 ENSG00000057935 "Metastasis associated 1 family member 3" Q9BTC8 2 42494569-42756947 "Plasma proteins, Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 70.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 137.0;Oligodendrocyte precursor cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039433 Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 63: T-cells - Adaptive immune response" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Vesicles "HPA039433: AB_10794747" "unprognostic (5.40e-2)" "unprognostic (4.89e-2)" "unprognostic (5.28e-2)" "prognostic unfavorable (2.30e-4)" "unprognostic (4.13e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (4.69e-4)" "unprognostic (7.55e-2)" "unprognostic (2.04e-1)" "unprognostic (5.43e-2)" "unprognostic (2.27e-1)" "unprognostic (1.58e-1)" "unprognostic (2.64e-2)" "unprognostic (9.03e-2)" "unprognostic (2.05e-1)" "unprognostic (3.47e-1)" "unprognostic (1.28e-2)" 11.8 41.8 16.4 5.6 18.9 1.6 14.9 9.1 19.4 18.5 7.1 16.6 7.8 16.8 27.5 21.8 16.1 10.0 12.4 21.9 14.9 13.6 7.9 8.8 10.7 12.3 13.9 29.2 18.8 17.3 15.1 15.3 18.8 14.4 13.2 9.3 13.6 16.8 9.1 19.1 11.4 12.0 11.7 7.8 16.8 21.0 16.1 70.4 12.6 9.9 14.5 15.3 17.8 14.8 13.0 16.6 20.1 14.3 17.4 28.0 46.6 7.4 18.6 21.7 19.2 22.2 26.2 45.4 12.6 22.1 15.9 8.2 51.6 25.2 34.2 14.1 21.0 6.7 8.8 36.4 21.9 5.0 29.0 29.5 29.1 13.4 16.6 28.1 30.4 23.9 16.5 6.1 25.7 27.8 30.3 22.0 84.4 20.8 9.7 18.4 18.9 0.0 25.7 12.1 12.3 37.1 13.5 45.5 17.8 61.6 23.2 7.0 14.2 8.9 12.1 7.2 8.1 11.5 4.7 63.5 12.6 5.7 11.1 2.5 0.9 0.0 1.7 0.6 2.6 1.2 2.0 2.9 1.5 1.3 4.4 3.0 0.2 1.8 0.9 0.4 1.1 1.5 16.4 18.9 9.1 19.4 21.9 14.9 12.3 13.9 18.8 11.7 16.1 14.8 12.7 12.8 12.5 60.4 10.8 15.3 21.1 33.0 15.4 0.0 24.6 19.6 12.5 15.7 25.7 22.0 0.0 58.5 5.1 19.1 17.6 22.9 10.7 44.5 23.1 13.1 9.6 2.5 137.0 28.0 42.0 21.7 31.1 32.3 12.0 72.3 20.7 13.3 12.4 0.0 81.8 20.0 50.8 6.6 7.1 26.0 33.8 5.2 17.8 53.4 6.9 0.0 9.2 106.1 65.9 20.2 21.8 39.9 10.9 17.7 25.2 33.1 18.4 0.0 13.1 15.8 35.9 25.5 41.1 24.5 18.3 59.9 12.6 44.5 21.5 17.3 MTFR2 "DUFD1, FAM54A" ENSG00000146410 "Mitochondrial fission regulator 2" Q6P444 6 136231024-136250335 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.3;lymphoid tissue: 6.4;testis: 7.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 23.6;Spermatocytes: 27.6;Spermatogonia: 13.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA029792, HPA029794" Approved Uncertain Vesicles NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "HPA029792: AB_10600210, HPA029794: AB_10600535" "unprognostic (6.49e-3)" "unprognostic (6.29e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (9.64e-4)" "unprognostic (3.93e-1)" "unprognostic (1.75e-2)" "unprognostic (4.60e-6)" "prognostic unfavorable (8.28e-4)" "unprognostic (3.77e-2)" "unprognostic (1.22e-1)" "unprognostic (6.27e-2)" "unprognostic (6.54e-2)" "unprognostic (1.11e-16)" "unprognostic (8.82e-3)" "unprognostic (1.55e-1)" "unprognostic (4.10e-2)" "unprognostic (3.64e-2)" 0.8 0.5 0.4 3.6 0.3 16.3 1.0 0.4 0.6 0.6 0.2 2.9 2.8 0.5 0.3 2.6 0.3 0.3 0.3 0.4 0.3 0.6 0.4 1.2 6.4 0.4 0.5 0.3 0.4 0.0 0.4 1.8 0.3 0.4 3.8 0.5 0.8 0.2 1.2 1.9 2.3 1.1 0.4 2.2 1.2 7.0 0.4 6.2 0.3 0.1 5.3 0.8 0.9 0.4 15.2 11.5 9.7 18.2 1.6 2.8 17.4 19.6 13.6 22.8 31.7 20.7 12.2 39.2 11.7 7.9 30.1 23.1 22.3 14.4 33.8 22.1 17.1 31.0 7.8 18.9 1.0 57.4 28.1 2.3 3.1 25.5 16.1 2.7 12.4 33.8 33.9 29.6 17.2 20.2 32.5 47.8 9.8 20.2 14.1 29.3 15.5 19.7 9.9 11.6 7.7 7.6 12.4 21.5 11.3 11.9 9.1 39.1 6.8 11.3 11.8 40.2 30.4 11.2 28.3 26.1 6.5 38.5 17.6 0.0 0.2 0.0 0.3 0.9 0.1 0.4 0.4 0.7 0.9 0.3 0.0 0.4 0.0 0.0 0.7 0.7 0.7 0.3 0.4 0.3 0.4 0.6 0.4 0.3 0.4 0.5 0.3 0.4 0.4 0.4 2.0 0.0 1.1 0.0 2.2 1.0 0.6 3.1 0.0 0.0 3.4 3.6 0.4 0.0 2.3 0.0 0.0 8.4 1.3 2.2 0.0 1.1 7.9 2.4 1.3 1.7 0.0 9.9 0.5 2.5 23.6 1.5 2.6 2.5 1.3 3.5 0.7 0.5 6.6 0.0 0.4 2.1 4.1 3.8 2.1 5.9 0.3 2.5 0.0 1.0 2.3 0.0 1.0 0.5 0.0 1.3 0.4 0.0 7.4 1.2 1.3 1.4 2.5 0.0 0.0 5.3 1.8 27.6 13.0 5.3 0.3 3.0 3.1 0.8 4.6 0.9 MTHFSD FLJ12998 ENSG00000103248 "Methenyltetrahydrofolate synthetase domain containing" Q2M296 16 86530178-86555235 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 35.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041333 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Vesicles" "HPA041333: AB_10795006" "unprognostic (4.09e-2)" "unprognostic (2.52e-2)" "prognostic unfavorable (9.88e-5)" "unprognostic (2.66e-2)" "unprognostic (7.71e-2)" "unprognostic (1.66e-1)" "unprognostic (4.90e-2)" "unprognostic (6.24e-2)" "unprognostic (3.29e-1)" "unprognostic (4.05e-2)" "unprognostic (2.96e-2)" "unprognostic (3.90e-3)" "unprognostic (1.94e-3)" "unprognostic (1.00e-1)" "unprognostic (1.05e-1)" "unprognostic (4.77e-1)" "unprognostic (5.85e-3)" 7.2 8.2 5.3 8.7 6.5 6.3 10.4 6.3 6.2 9.2 7.6 8.7 7.4 9.6 10.6 10.1 13.0 8.4 7.9 5.2 5.1 7.6 7.9 8.3 11.7 6.4 6.2 11.5 9.9 11.8 9.3 8.1 6.4 10.2 10.5 6.6 11.0 8.1 11.3 12.7 8.6 8.3 6.1 10.6 9.7 17.7 6.4 10.6 11.0 8.3 11.7 8.9 8.8 9.6 15.7 14.6 14.2 12.3 11.8 18.0 17.0 15.3 11.1 19.0 9.4 13.0 25.8 14.2 16.3 13.4 10.2 21.4 15.8 15.0 17.7 9.4 12.8 12.9 20.0 12.0 16.0 10.1 6.9 11.4 23.4 24.4 20.9 16.4 11.5 20.5 26.9 0.0 13.9 19.8 12.6 15.0 9.3 12.9 18.3 38.6 8.0 11.2 11.1 9.4 13.8 9.5 34.7 6.8 12.6 14.1 34.5 10.3 11.9 18.3 15.7 12.2 15.1 11.1 14.7 41.6 16.7 15.8 18.2 5.9 4.8 2.4 4.7 3.5 5.0 4.6 5.2 4.9 6.0 3.4 4.2 5.0 1.9 6.3 4.3 2.7 4.5 4.8 5.3 6.5 6.3 6.2 5.2 5.1 6.4 6.2 6.4 6.1 6.4 9.6 6.4 6.4 5.9 10.4 6.4 1.1 2.7 4.2 1.2 0.0 6.8 7.1 4.4 2.8 4.7 5.5 0.0 7.9 5.6 7.2 11.7 5.2 35.6 7.4 5.9 4.6 4.2 7.4 6.6 4.2 4.5 4.5 2.6 4.9 4.5 9.4 5.7 3.4 6.1 0.0 7.1 5.3 2.0 5.5 2.0 18.8 6.5 4.3 3.6 3.7 4.7 0.0 6.2 5.5 13.5 3.6 3.6 8.2 4.1 2.6 5.3 4.4 8.2 0.0 6.6 2.2 5.5 11.4 4.0 4.5 1.4 7.7 3.8 5.7 5.5 2.0 MTMR1 ENSG00000063601 "Myotubularin related protein 1" Q13613 X 150692971-150765108 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 79.3;Excitatory neurons: 61.2;Inhibitory neurons: 58.1;Oligodendrocyte precursor cells: 54.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-698: 104.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018502, HPA075953" Approved Approved Vesicles NA NA "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA018502: AB_1854185, HPA075953: " "unprognostic (2.37e-2)" "unprognostic (1.64e-3)" "unprognostic (2.07e-1)" "unprognostic (1.05e-2)" "unprognostic (4.34e-2)" "unprognostic (1.14e-1)" "unprognostic (1.97e-1)" "unprognostic (1.34e-1)" "unprognostic (4.35e-2)" "unprognostic (3.16e-1)" "unprognostic (7.48e-2)" "unprognostic (1.41e-2)" "unprognostic (1.67e-2)" "unprognostic (1.32e-2)" "unprognostic (1.93e-1)" "unprognostic (3.19e-1)" "unprognostic (8.40e-2)" 6.7 7.2 11.3 11.1 13.0 11.9 12.5 11.7 13.0 9.3 7.1 10.2 9.0 7.9 7.1 20.6 9.7 7.2 12.2 17.3 10.8 8.3 9.0 9.5 21.8 7.5 10.0 8.5 10.0 17.9 9.2 14.2 7.6 10.9 9.4 22.1 12.4 10.9 22.9 21.4 10.4 7.3 9.2 14.3 10.7 8.0 11.9 31.3 10.0 16.0 25.5 12.6 13.5 8.7 32.3 20.3 21.5 17.7 4.9 5.7 28.8 28.1 36.0 28.0 39.4 19.8 24.9 70.2 40.1 22.9 27.1 28.4 43.9 40.8 43.2 28.4 26.3 4.4 31.6 8.5 14.5 20.7 14.6 15.6 27.7 30.8 0.4 26.8 17.1 22.9 13.8 17.5 20.3 27.7 30.6 5.3 9.9 35.9 30.3 16.0 34.1 31.2 22.0 36.4 31.9 19.9 10.7 23.7 8.8 17.0 30.3 11.8 21.7 18.3 14.6 2.3 42.1 22.2 24.6 104.8 3.7 13.3 14.4 0.0 0.5 5.0 2.1 0.9 1.5 1.7 2.3 1.9 1.4 1.9 2.0 2.8 1.5 3.9 0.9 5.0 3.2 1.2 11.3 13.0 11.7 13.0 17.3 10.8 7.5 10.0 7.6 9.2 11.9 8.7 3.7 16.0 6.5 79.3 11.4 11.2 11.0 8.0 6.8 0.0 7.8 5.5 8.2 2.8 7.5 5.5 0.0 10.1 19.3 4.6 0.0 5.9 0.0 10.0 3.7 3.6 9.6 6.5 61.2 6.6 7.3 4.5 7.7 9.2 1.3 4.8 2.9 8.0 4.6 0.0 58.1 5.5 8.2 9.4 8.8 1.7 5.6 4.8 3.6 30.0 6.2 0.0 8.2 54.8 22.6 10.6 8.6 5.3 7.9 11.0 3.8 3.1 8.4 0.0 6.6 6.7 3.9 2.5 3.0 10.3 16.8 10.4 8.8 5.9 5.9 12.5 MTMR2 "CMT4B, KIAA1073" ENSG00000087053 "Myotubularin related protein 2" Q13614 11 95821766-95925315 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 120.1;Oligodendrocytes: 226.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049831 Approved Supported Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 15: RT4 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA049831: AB_2680904" "unprognostic (1.71e-2)" "unprognostic (2.55e-3)" "unprognostic (7.81e-3)" "unprognostic (4.16e-1)" "unprognostic (4.18e-3)" "unprognostic (5.36e-2)" "prognostic unfavorable (1.61e-8)" "unprognostic (3.23e-3)" "unprognostic (3.42e-2)" "unprognostic (1.77e-2)" "prognostic unfavorable (3.60e-4)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (1.54e-1)" "unprognostic (1.50e-1)" "unprognostic (1.14e-1)" "unprognostic (8.03e-3)" 14.7 9.3 11.0 11.2 16.8 4.4 11.8 16.3 18.3 12.2 12.2 12.9 7.1 12.3 6.2 14.7 12.4 14.3 13.5 10.8 14.3 16.4 4.3 12.3 9.5 15.1 14.4 11.5 7.8 12.7 6.4 24.5 15.8 16.1 13.9 18.6 20.5 11.4 6.2 8.2 8.3 18.0 13.5 8.6 13.0 31.0 14.1 15.1 9.9 8.9 12.1 15.2 10.4 22.4 24.1 25.3 54.1 39.2 19.2 29.0 47.5 43.3 37.9 42.4 37.8 57.3 47.1 16.2 50.3 45.5 35.9 30.9 47.7 48.2 38.9 30.8 21.3 31.5 55.0 33.0 42.8 59.3 26.7 24.0 31.2 56.6 54.5 41.8 64.4 35.4 44.7 14.2 39.6 17.9 29.0 27.2 46.6 59.0 34.9 23.2 32.2 16.8 43.9 125.0 35.6 40.6 43.6 36.4 19.2 35.1 27.6 26.5 64.4 47.7 45.1 34.4 41.1 13.1 42.4 14.3 20.4 15.6 50.6 9.8 3.9 1.7 12.4 4.7 13.4 5.8 7.9 15.7 7.6 4.9 4.0 11.3 0.9 14.1 7.2 3.7 8.1 7.8 11.0 16.8 16.3 18.3 10.8 14.3 15.1 14.4 15.8 13.5 14.1 22.4 19.6 3.2 8.6 28.7 9.6 10.3 15.0 9.0 8.6 0.0 8.0 6.7 17.3 0.0 11.6 9.2 0.0 9.0 8.8 9.1 9.8 17.8 74.8 18.1 14.1 20.2 16.2 12.8 69.8 16.9 34.3 17.0 9.7 8.7 19.0 49.1 11.0 1.0 12.5 0.0 37.5 9.8 24.4 10.3 8.2 120.1 11.1 8.3 3.6 40.3 6.8 0.0 14.4 63.8 226.6 17.7 4.7 12.0 7.0 15.1 6.0 29.3 17.0 0.0 32.9 7.9 29.0 46.8 19.2 15.4 6.0 9.0 8.8 12.9 10.6 15.6 MTOR "FLJ44809, FRAP, FRAP1, FRAP2, RAFT1, RAPT1" ENSG00000198793 "Mechanistic target of rapamycin kinase" P42345 1 11106535-11262551 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB069425, HPA071227" Approved Approved Vesicles,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Vesicles, Cytosol" "CAB069425: , HPA071227: AB_2686367" "unprognostic (3.18e-1)" "unprognostic (1.50e-1)" "unprognostic (1.20e-1)" "unprognostic (2.45e-3)" "unprognostic (5.50e-2)" "unprognostic (2.55e-2)" "unprognostic (1.39e-1)" "unprognostic (1.68e-1)" "unprognostic (1.18e-1)" "unprognostic (8.24e-3)" "unprognostic (3.48e-2)" "unprognostic (1.88e-1)" "prognostic favorable (1.49e-5)" "unprognostic (1.27e-1)" "unprognostic (2.45e-1)" "unprognostic (6.60e-2)" "unprognostic (7.55e-2)" 16.3 19.4 18.2 13.5 19.0 14.0 16.8 18.4 20.1 15.2 18.6 22.8 11.0 17.5 21.8 18.3 14.6 9.0 23.6 19.7 17.7 24.1 27.6 15.2 15.3 16.5 21.2 14.2 18.3 20.6 21.8 11.8 18.4 19.8 16.0 26.9 16.5 13.8 36.4 17.1 19.6 13.8 14.6 21.2 18.7 33.8 22.7 19.2 17.8 17.8 15.9 17.1 14.9 18.7 28.5 25.2 33.3 25.4 39.4 18.6 16.6 23.4 22.3 30.6 29.9 26.0 25.5 31.4 19.6 27.8 18.8 33.1 45.3 35.8 39.3 25.2 33.2 41.7 53.8 33.4 24.7 41.1 29.7 24.0 26.8 43.7 44.0 14.5 39.3 29.6 47.4 26.1 21.6 32.4 28.5 31.2 25.3 29.6 23.5 28.2 39.2 21.0 27.2 25.3 33.4 24.5 50.1 26.8 31.2 36.5 21.8 24.0 42.3 26.5 23.9 20.5 31.8 25.5 25.5 60.5 19.1 43.6 28.6 0.3 1.1 1.3 1.9 2.4 1.6 1.4 1.1 1.0 1.6 1.1 1.3 1.1 0.8 1.1 1.3 1.2 2.4 1.0 18.2 19.0 18.4 20.1 19.7 17.7 16.5 21.2 18.4 14.6 22.7 18.7 9.2 16.0 11.8 40.8 10.0 3.4 5.2 7.6 8.6 0.0 7.7 7.5 25.1 2.8 10.3 9.2 0.0 7.9 9.8 9.4 1.9 8.5 42.0 13.8 16.1 11.0 10.3 14.3 43.8 6.2 7.2 9.2 16.8 18.6 13.3 12.9 5.3 13.4 6.9 0.0 49.2 7.8 6.1 8.2 4.1 36.1 7.8 9.1 8.8 36.5 9.2 0.0 10.3 38.2 37.4 10.4 5.4 8.2 17.2 8.9 7.0 4.5 6.3 0.0 39.5 11.4 12.1 49.3 37.4 15.6 5.7 9.9 9.8 15.3 10.0 5.7 MUC5B "MG1, MUC5" ENSG00000117983 "Mucin 5B, oligomeric mucus/gel-forming" Q9HC84 11 1223066-1262172 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "salivary gland: 2621.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 443.2;Distal enterocytes: 158.4;Intestinal goblet cells: 210.1;Undifferentiated cells: 183.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "OE19: 113.9;PC-3: 120.0" "Not detected" "Not detected" "HPA008246, CAB009396" Enhanced Supported Vesicles "Secreted in other tissues" NA NA 1300000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB009396: AB_2282256, HPA008246: AB_1854203" "unprognostic (2.01e-2)" "unprognostic (1.46e-1)" "unprognostic (9.39e-2)" "unprognostic (2.76e-3)" "unprognostic (5.46e-2)" "unprognostic (1.22e-1)" "unprognostic (4.89e-2)" "unprognostic (7.80e-3)" "unprognostic (3.75e-1)" "unprognostic (1.11e-1)" "unprognostic (4.18e-2)" "unprognostic (8.95e-2)" "unprognostic (2.57e-7)" "unprognostic (2.71e-1)" "unprognostic (1.61e-1)" "unprognostic (1.07e-1)" "unprognostic (8.13e-2)" 0.1 0.7 0.2 2.0 0.1 0.0 1.3 0.0 0.4 229.4 0.0 58.0 0.1 0.3 0.0 101.0 1.1 221.3 0.1 0.0 0.0 0.1 2.4 7.5 0.0 0.1 0.0 0.1 9.8 0.0 0.4 0.0 0.0 0.6 17.1 0.0 2621.9 0.0 0.3 0.4 2.6 0.6 0.0 0.0 6.9 0.3 0.0 0.0 0.2 0.0 0.4 0.2 0.1 0.0 0.0 17.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.1 0.2 0.0 113.9 120.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 32.8 0.0 2.3 0.0 0.0 6.7 0.6 0.0 6.4 4.3 12.4 443.2 64.0 0.0 0.0 0.1 0.0 158.4 0.0 0.9 0.0 1.4 0.8 0.9 24.5 0.0 0.1 0.0 0.1 1.1 12.8 7.2 4.5 0.0 0.0 1.2 0.2 0.0 0.0 210.1 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 53.4 0.0 1.4 1.3 0.1 0.2 24.5 0.0 0.0 0.0 3.0 0.0 0.5 1.6 0.0 0.1 0.7 0.1 183.1 1.1 MVB12A "FAM125A, FLJ32495" ENSG00000141971 "Multivesicular body subunit 12A" Q96EY5 19 17405722-17433724 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041885, HPA042231" Approved Supported Vesicles NA No "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA041885: AB_10964218, HPA042231: AB_10961043" "unprognostic (1.34e-2)" "prognostic favorable (3.26e-4)" "unprognostic (1.48e-1)" "unprognostic (2.35e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-2)" "unprognostic (5.96e-3)" "unprognostic (8.49e-2)" "unprognostic (1.80e-1)" "unprognostic (1.77e-1)" "unprognostic (9.93e-2)" "unprognostic (3.87e-2)" "unprognostic (2.29e-1)" "unprognostic (2.54e-1)" "unprognostic (2.89e-1)" "unprognostic (1.75e-1)" "unprognostic (1.33e-2)" 21.3 28.4 10.5 17.3 11.5 18.2 21.4 11.4 12.3 18.6 11.8 16.7 29.1 17.3 7.4 29.5 22.0 18.7 13.1 10.0 10.3 20.2 19.9 15.5 21.7 14.0 11.0 34.0 20.0 22.2 7.4 19.2 11.6 13.7 11.6 1.2 24.2 17.5 14.4 24.7 22.0 11.6 12.3 22.3 20.9 5.2 11.4 24.0 21.2 12.4 19.3 17.0 18.0 13.5 51.2 23.4 12.1 33.9 15.7 28.8 71.1 18.3 28.4 33.8 40.8 20.1 60.5 32.7 52.7 28.2 28.8 25.5 19.5 35.5 9.0 37.6 60.7 9.5 41.8 44.0 50.3 13.0 29.1 28.2 28.5 29.1 18.0 25.5 40.7 29.9 26.8 65.2 15.6 32.2 24.6 26.2 17.0 40.8 63.9 34.7 14.8 53.1 32.4 21.2 25.3 40.7 19.6 30.2 77.6 10.9 40.1 30.9 21.7 31.5 18.4 35.1 20.5 59.3 72.9 35.0 34.1 49.3 38.9 57.4 61.7 42.9 33.0 66.9 31.0 23.3 34.0 32.0 60.5 29.8 28.0 27.5 36.0 38.2 53.4 53.3 57.2 36.2 10.5 11.5 11.4 12.3 10.0 10.3 14.0 11.0 11.6 12.3 11.4 13.5 67.5 9.6 8.2 5.9 16.4 39.0 41.4 65.1 42.1 5.3 53.6 61.8 5.6 48.6 33.5 46.0 6.2 60.7 18.1 85.0 54.8 78.7 13.5 30.1 26.8 47.7 26.5 8.4 2.2 48.4 99.0 38.6 43.3 30.2 21.6 45.7 62.4 28.0 72.3 3.3 3.2 48.5 50.8 44.9 30.8 16.3 43.5 31.2 32.0 11.2 46.7 32.7 19.6 4.0 7.3 63.4 84.1 47.0 23.5 19.0 104.4 61.3 36.4 13.8 6.6 22.8 40.9 11.8 12.3 58.3 43.9 40.6 21.2 44.3 57.1 45.0 MVB12B "C9orf28, FAM125B, FLJ00001" ENSG00000196814 "Multivesicular body subunit 12B" Q9H7P6 9 126326829-126507041 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 99.3" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 505.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 34.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043683, HPA049383" Approved "Golgi apparatus,Vesicles" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Vesicles" "HPA043683: AB_2678616, HPA049383: AB_2680737" "unprognostic (3.50e-1)" "unprognostic (1.12e-1)" "unprognostic (6.82e-2)" "unprognostic (9.59e-3)" "unprognostic (4.77e-2)" "unprognostic (1.13e-1)" "unprognostic (4.22e-2)" "unprognostic (4.45e-3)" "unprognostic (4.33e-1)" "unprognostic (1.05e-1)" "prognostic favorable (7.89e-4)" "unprognostic (2.82e-1)" "unprognostic (1.66e-3)" "unprognostic (3.06e-1)" "unprognostic (1.71e-1)" "unprognostic (5.79e-2)" "unprognostic (1.12e-3)" 5.8 5.2 32.5 4.5 63.6 12.3 4.8 58.6 44.5 6.4 27.6 8.2 3.7 6.8 3.0 4.1 9.9 3.8 5.4 32.0 40.1 4.4 4.2 18.0 6.9 81.1 59.4 6.4 3.2 7.7 8.3 15.0 68.4 6.6 6.2 6.2 3.1 8.4 24.6 5.0 5.5 6.4 57.2 11.1 6.4 5.7 56.7 8.4 5.8 13.0 2.6 7.9 5.0 99.3 4.8 6.5 34.6 19.1 1.2 0.4 20.4 4.0 3.1 7.0 1.3 5.6 0.3 0.0 2.4 3.8 10.3 2.1 10.7 1.9 4.3 8.0 6.7 1.7 1.1 24.6 2.7 3.2 1.5 2.6 3.5 1.4 0.1 5.8 5.4 25.5 0.0 0.0 5.2 3.9 5.3 10.0 7.6 0.8 8.6 7.6 18.9 0.0 0.3 19.5 8.7 15.9 6.4 4.6 4.1 14.4 4.6 19.2 7.9 7.8 5.8 4.4 8.2 0.1 0.0 1.9 2.2 14.2 4.2 0.0 0.8 0.1 1.4 0.2 2.5 0.1 0.6 2.3 1.0 0.2 0.1 1.0 0.0 0.0 0.2 0.0 0.0 0.9 32.5 63.6 58.6 44.5 32.0 40.1 81.1 59.4 68.4 57.2 56.7 99.3 6.3 6.4 7.3 75.4 1.8 3.6 3.2 1.0 6.8 9.4 3.3 3.6 3.6 4.3 1.3 1.8 4.2 12.4 4.7 8.8 0.0 1.6 0.8 6.2 3.0 5.8 2.4 1.7 64.5 1.4 2.6 3.1 2.6 2.4 7.0 5.5 2.2 6.2 1.6 10.1 58.2 2.5 6.1 23.3 6.2 2.7 2.8 10.2 0.0 74.9 3.9 9.1 2.1 56.8 505.6 1.0 5.5 6.4 2.2 1.2 0.9 0.3 6.9 5.3 0.0 2.6 2.7 3.4 6.4 2.9 2.6 3.4 10.9 0.8 3.0 1.6 MVK "LRBP, MK" ENSG00000110921 "Mevalonate kinase" Q03426 12 109573255-109598125 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Kinase, Transferase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 69.1" "Cell type enhanced" "Detected in all" "Early spermatids: 60.5;Horizontal cells: 62.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016961, HPA044110" Approved Supported Vesicles,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "Vesicles, Cytosol" "HPA016961: AB_1854220, HPA044110: " "unprognostic (3.10e-1)" "unprognostic (2.27e-2)" "unprognostic (1.85e-1)" "unprognostic (4.43e-2)" "unprognostic (3.66e-2)" "unprognostic (2.08e-2)" "unprognostic (4.30e-2)" "unprognostic (8.98e-2)" "unprognostic (1.05e-1)" "unprognostic (2.73e-2)" "unprognostic (8.23e-2)" "unprognostic (1.30e-1)" "unprognostic (6.43e-2)" "unprognostic (2.09e-1)" "unprognostic (1.58e-1)" "unprognostic (3.88e-1)" "unprognostic (3.28e-1)" 7.9 29.8 12.7 6.1 13.7 8.3 14.7 16.7 15.0 14.5 9.6 11.2 13.9 7.3 10.2 45.5 6.3 5.3 9.4 11.1 13.2 32.1 69.1 11.4 6.9 36.1 15.5 10.7 10.0 11.5 11.6 5.4 38.6 12.3 8.6 7.3 13.7 7.0 12.1 33.3 9.8 5.0 15.3 6.7 11.8 28.5 15.3 4.2 15.1 8.8 9.1 9.5 20.1 24.4 30.1 25.0 29.9 13.7 11.2 27.3 14.4 9.5 21.7 30.0 32.8 31.4 33.8 17.7 7.8 11.7 48.1 36.0 31.6 50.0 13.2 19.0 18.1 9.9 15.7 53.7 31.5 11.1 13.0 27.2 42.1 48.8 13.6 12.6 20.9 19.0 18.7 17.4 13.6 34.5 12.0 34.6 22.6 14.9 32.3 10.5 22.1 37.0 67.4 40.9 25.1 18.7 19.8 58.7 14.0 11.0 59.7 21.1 14.1 13.2 14.5 12.0 12.8 13.3 20.6 28.2 16.1 29.2 16.6 1.0 6.9 4.0 12.6 6.5 11.3 9.4 7.4 12.4 8.6 14.1 10.9 8.3 1.6 11.0 4.6 7.0 7.6 6.4 12.7 13.7 16.7 15.0 11.1 13.2 36.1 15.5 38.6 15.3 15.3 24.4 6.1 12.8 12.4 6.8 8.3 4.7 5.2 39.7 4.6 12.4 13.1 11.0 5.7 11.5 25.8 14.7 18.8 33.0 7.3 10.4 21.5 15.6 60.5 5.8 2.3 7.1 9.0 4.8 5.1 18.1 15.3 6.8 9.7 5.1 1.3 14.7 6.4 32.7 15.6 62.2 5.2 7.8 10.2 3.4 2.2 42.5 8.1 4.8 7.2 3.7 10.3 10.6 10.3 4.0 15.3 13.2 3.2 7.2 4.1 5.5 16.4 52.4 13.5 12.2 6.6 4.0 8.2 33.9 16.8 12.0 8.5 47.9 6.1 44.8 11.1 4.6 MYBBP1A "FLJ37886, P160, PAP2, Pol5" ENSG00000132382 "MYB binding protein 1a" Q9BQG0 17 4538897-4555386 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Ribosome biogenesis, Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005466 Supported Supported Nucleoli,Vesicles No No 47000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Nucleoli Vesicles "HPA005466: AB_2667327" "unprognostic (8.06e-2)" "unprognostic (2.33e-1)" "unprognostic (1.71e-1)" "unprognostic (9.01e-2)" "unprognostic (7.81e-2)" "unprognostic (1.29e-1)" "unprognostic (1.57e-3)" "unprognostic (2.22e-1)" "prognostic unfavorable (8.47e-4)" "unprognostic (1.84e-1)" "prognostic favorable (1.61e-4)" "unprognostic (3.88e-3)" "prognostic unfavorable (5.95e-4)" "unprognostic (1.78e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (8.12e-4)" "unprognostic (9.70e-2)" 12.3 11.0 3.8 13.4 3.8 11.4 15.9 1.3 7.6 13.3 0.8 11.9 9.6 14.6 4.6 17.0 15.2 6.2 11.0 5.0 4.2 9.8 10.8 11.4 13.8 5.2 4.9 14.1 24.4 6.7 12.7 5.2 3.5 17.1 5.1 3.8 18.9 10.1 27.9 22.0 12.9 7.3 2.1 14.0 12.4 8.1 3.4 7.4 11.2 8.0 8.7 14.9 13.8 3.8 60.1 90.0 11.9 56.2 15.4 17.1 40.8 39.8 17.5 39.5 30.8 67.1 24.4 80.4 47.2 23.9 19.8 74.2 50.1 61.3 19.0 40.3 133.8 38.8 58.3 62.2 25.2 45.5 34.7 25.7 34.6 58.8 29.1 11.0 26.6 45.0 64.2 37.1 18.2 51.4 54.2 19.5 56.0 19.1 48.0 69.8 19.7 54.0 9.8 45.5 25.5 48.5 40.8 29.7 28.2 8.6 27.5 19.1 34.3 35.1 31.5 32.7 118.6 32.1 26.5 34.4 32.5 53.9 45.3 0.0 1.9 0.3 2.8 1.6 3.4 2.9 2.3 3.1 2.9 1.7 2.5 2.8 0.1 2.4 3.4 2.1 1.0 2.7 3.8 3.8 1.3 7.6 5.0 4.2 5.2 4.9 3.5 2.1 3.4 3.8 13.4 9.6 14.5 4.6 13.1 12.9 6.8 7.1 12.0 8.2 12.9 14.4 4.1 8.6 13.3 3.7 12.5 2.9 5.8 9.2 0.0 7.7 0.5 6.7 15.3 17.0 11.4 7.2 11.3 12.7 5.4 10.2 10.7 8.5 5.1 12.2 8.6 7.8 6.5 10.1 6.1 8.0 4.1 4.5 6.8 0.6 5.6 6.3 3.6 7.5 3.8 3.8 6.2 3.5 6.5 8.2 4.5 12.0 13.7 13.9 4.6 3.2 12.2 6.2 6.6 10.8 12.9 2.6 11.1 12.8 11.9 1.1 9.7 13.8 12.4 6.2 MYBPHL ENSG00000221986 "Myosin binding protein H like" A2RUH7 1 109292365-109307011 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "heart muscle: 105.8" "Cell type enriched" "Detected in some" 6 "Cardiomyocytes: 156.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 2.5;RH-30: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA077633 Approved Vesicles NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Vesicles "HPA077633: " "unprognostic (6.07e-3)" "unprognostic (1.43e-1)" "unprognostic (2.78e-1)" "unprognostic (1.17e-2)" "unprognostic (1.47e-1)" "unprognostic (1.37e-1)" "unprognostic (1.80e-2)" "unprognostic (1.24e-2)" "unprognostic (5.53e-2)" "unprognostic (5.89e-1)" "unprognostic (5.22e-3)" "unprognostic (4.10e-1)" "unprognostic (7.05e-9)" "unprognostic (6.01e-2)" "unprognostic (1.53e-1)" "unprognostic (5.81e-2)" "unprognostic (2.64e-1)" 0.0 0.1 0.6 0.0 1.2 0.0 0.0 0.4 2.8 0.0 0.0 0.0 0.0 0.0 0.4 0.6 2.3 0.0 105.8 2.2 0.5 0.0 0.0 1.2 0.0 0.6 0.6 0.0 0.0 0.0 3.0 0.0 0.6 0.0 0.0 2.0 0.0 0.0 0.6 0.0 0.1 0.0 0.3 0.0 0.5 0.5 0.6 0.0 0.0 0.6 0.0 0.1 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.2 0.4 2.8 2.2 0.5 0.6 0.6 0.6 0.3 0.6 2.4 0.0 0.0 5.1 0.3 0.0 0.0 0.1 0.7 0.0 1.8 0.1 0.1 156.7 0.0 1.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.1 0.0 0.0 3.1 0.0 0.0 11.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.5 2.2 0.1 0.0 0.7 0.0 0.0 0.0 0.1 0.8 11.1 0.0 25.0 1.6 0.3 0.6 0.0 0.1 0.0 0.1 0.1 0.0 0.4 MYCBP2 "FLJ10106, KIAA0916, PAM, PHR1" ENSG00000005810 "MYC binding protein 2" O75592 13 77044657-77327094 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Ubl conjugation pathway" "Guanine-nucleotide releasing factor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 425.4;Inhibitory neurons: 471.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HL-60: 110.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058807 Supported Nucleoplasm,Vesicles,Cytosol "Intracellular and membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Vesicles, Cytosol" "HPA058807: AB_2732627" "unprognostic (1.79e-1)" "unprognostic (1.25e-1)" "unprognostic (1.60e-1)" "unprognostic (1.06e-1)" "unprognostic (1.75e-1)" "unprognostic (2.03e-2)" "unprognostic (8.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.09e-1)" "unprognostic (1.80e-1)" "unprognostic (1.48e-1)" "unprognostic (6.42e-2)" "prognostic favorable (5.01e-5)" "unprognostic (2.63e-1)" "unprognostic (9.84e-2)" "unprognostic (4.04e-2)" "unprognostic (1.00e-1)" 69.9 22.2 42.3 19.0 46.2 32.8 49.3 37.3 52.4 43.4 18.8 29.4 9.0 27.2 29.8 45.9 29.2 12.5 32.9 48.6 35.9 22.6 24.5 28.3 40.0 34.6 29.6 43.1 30.9 14.9 32.3 10.9 36.9 28.0 12.5 28.9 29.1 13.3 26.5 79.7 34.8 11.9 30.1 56.4 24.9 26.3 33.9 34.6 27.2 18.1 37.8 30.4 41.5 38.7 21.6 10.8 12.9 14.1 62.9 27.9 7.5 13.4 19.8 11.5 14.7 9.7 11.0 61.4 8.3 26.6 11.2 19.5 22.4 24.7 15.5 24.5 22.2 52.2 22.2 20.1 21.4 110.8 17.7 31.5 20.2 10.6 20.8 11.4 26.5 22.3 11.3 18.8 20.7 13.1 30.5 74.3 6.8 28.7 13.6 34.2 13.1 15.0 19.6 21.1 20.2 9.4 16.2 23.1 12.8 13.0 8.6 83.8 35.0 10.9 9.1 7.3 13.0 20.3 15.0 42.7 22.1 89.2 11.3 1.4 2.0 2.0 3.2 2.1 2.8 4.9 3.6 2.8 1.9 4.3 4.1 3.2 1.8 2.8 1.6 2.7 4.5 1.4 42.3 46.2 37.3 52.4 48.6 35.9 34.6 29.6 36.9 30.1 33.9 38.7 92.2 38.5 52.2 158.7 170.3 82.3 39.9 32.6 63.7 229.3 36.8 38.4 69.7 25.8 30.9 35.0 104.3 46.1 109.2 14.2 1.9 26.1 56.0 50.9 61.1 83.8 32.6 46.9 425.4 33.1 31.5 80.6 38.2 66.6 48.2 34.0 44.6 52.4 41.8 218.7 471.3 19.7 26.4 106.9 48.2 23.4 65.9 100.4 32.0 282.9 116.7 121.5 120.5 338.8 212.5 30.2 15.8 96.3 121.9 53.7 15.2 13.2 19.5 94.8 105.2 76.7 76.0 81.5 71.6 129.1 150.7 43.9 121.5 67.4 28.1 42.4 MYCBPAP "AMAP-1, DKFZp434N1415" ENSG00000136449 "MYCBP associated protein" Q8TBZ2 17 50508384-50531501 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "testis: 65.1" "Cell type enhanced" "Detected in many" "Early spermatids: 224.2;Late spermatids: 145.2;Respiratory ciliated cells: 40.4;Spermatocytes: 69.9;Theca cells: 54.9" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 4.4;JURKAT: 3.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA023257, HPA024405" Enhanced Approved Vesicles NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA023257: AB_2671126, HPA024405: " "unprognostic (2.05e-2)" "unprognostic (1.79e-2)" "unprognostic (9.13e-3)" "unprognostic (3.98e-5)" "unprognostic (8.62e-4)" "unprognostic (3.65e-2)" "unprognostic (1.52e-3)" "unprognostic (1.61e-1)" "unprognostic (2.38e-3)" "unprognostic (1.11e-1)" "unprognostic (7.32e-4)" "unprognostic (2.52e-1)" "unprognostic (1.39e-4)" "unprognostic (7.15e-2)" "unprognostic (1.97e-1)" "unprognostic (7.37e-2)" "unprognostic (2.02e-2)" 0.7 0.8 1.7 0.6 1.8 1.3 0.4 2.4 3.4 1.2 3.4 0.4 0.2 0.9 1.1 0.8 5.3 1.0 0.6 1.3 1.0 0.8 0.2 1.5 1.0 2.9 2.4 2.5 0.2 0.4 0.9 0.3 1.4 1.0 0.4 1.1 0.8 1.3 1.1 1.0 0.3 0.9 1.5 0.6 0.4 65.1 1.6 0.9 0.8 0.3 0.6 0.3 0.5 1.1 0.1 0.8 0.3 0.3 0.8 0.4 0.8 0.7 0.3 0.2 0.2 0.4 2.0 0.2 0.1 0.2 0.8 0.3 0.1 0.9 0.2 4.4 0.2 1.3 1.3 0.4 0.7 0.1 0.2 1.2 0.2 0.4 1.8 0.8 0.6 3.8 0.2 0.4 0.6 0.1 0.2 0.3 0.1 0.1 0.5 0.1 0.2 0.2 0.0 0.2 0.6 1.6 0.3 0.2 0.1 0.5 0.3 0.8 2.0 0.3 0.4 0.1 0.1 2.3 0.8 0.1 0.5 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 1.7 1.8 2.4 3.4 1.3 1.0 2.9 2.4 1.4 1.5 1.6 1.1 0.3 0.0 1.7 7.2 0.7 0.1 1.4 0.7 0.0 3.6 0.4 0.3 0.9 0.0 6.5 1.8 0.0 2.4 1.7 0.4 0.0 0.1 224.2 18.6 1.2 1.1 0.0 3.6 2.5 0.4 0.3 2.0 0.0 0.6 0.0 5.6 0.0 0.0 0.4 0.0 2.2 1.8 0.0 0.6 0.5 145.2 6.8 0.6 0.0 2.8 0.0 4.3 3.1 0.5 1.0 0.1 0.1 3.8 0.6 1.1 1.4 0.2 40.4 0.5 0.0 2.7 1.4 69.9 7.6 0.1 0.4 0.1 1.4 54.9 0.4 0.8 MYCT1 "FLJ21269, MTLC" ENSG00000120279 "MYC target 1" Q8N699 6 152697895-152724567 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 49.6" "Group enriched" "Detected in some" 5 "Adipocytes: 123.0;Endothelial cells: 141.3;Hepatic stellate cells: 230.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 33 "eosinophil: 30.7" "Lineage enriched" "Detected in single" 248 "granulocytes: 30.7" "Group enriched" "Detected in some" 5 "HUVEC TERT2: 124.6;TIME: 104.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047992 Approved Nucleoplasm,Vesicles NA NA 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Vesicles "HPA047992: " "unprognostic (2.92e-1)" "unprognostic (1.82e-1)" "unprognostic (5.95e-2)" "unprognostic (2.06e-1)" "unprognostic (6.73e-2)" "unprognostic (6.80e-2)" "unprognostic (4.64e-3)" "unprognostic (6.78e-2)" "unprognostic (9.90e-2)" "unprognostic (2.10e-1)" "unprognostic (2.66e-2)" "unprognostic (2.18e-2)" "prognostic unfavorable (4.73e-4)" "unprognostic (1.26e-3)" "unprognostic (1.08e-1)" "unprognostic (1.25e-1)" "unprognostic (3.36e-2)" 26.6 3.2 6.8 5.2 6.9 1.2 21.4 6.9 10.2 9.0 5.2 6.1 3.5 10.1 4.5 4.6 9.2 10.5 17.1 6.3 7.1 6.6 13.1 15.6 6.2 7.7 6.9 3.6 2.7 4.3 2.2 20.7 8.6 4.4 5.8 1.0 3.7 3.8 12.8 4.7 5.6 12.4 6.8 49.6 4.5 1.8 10.0 2.5 12.2 20.5 3.0 8.1 7.3 7.5 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.0 17.7 0.1 0.0 0.2 0.0 0.1 0.0 23.0 0.3 0.0 0.7 0.1 0.1 0.0 0.2 0.2 0.3 0.0 124.6 0.0 0.3 0.3 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 2.1 0.0 0.0 104.4 0.5 0.8 1.5 0.0 1.1 0.0 15.6 0.0 0.0 0.0 0.9 0.0 30.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.1 0.0 0.1 0.0 0.6 6.8 6.9 6.9 10.2 6.3 7.1 7.7 6.9 8.6 6.8 10.0 7.5 123.0 0.0 5.2 0.7 0.8 7.1 0.2 0.1 2.8 0.2 0.4 0.9 3.1 2.8 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 10.2 1.3 0.2 141.3 0.0 13.7 0.1 0.2 0.0 4.0 0.0 0.1 1.3 0.0 230.6 2.1 0.1 0.0 0.1 0.0 0.0 7.3 7.3 3.7 0.3 13.3 14.2 30.9 0.1 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.6 0.5 0.0 0.0 17.7 0.0 0.0 1.5 2.2 0.1 0.1 0.5 5.5 0.0 0.9 0.5 0.0 0.7 MYD88 ENSG00000172936 "MYD88 innate immune signal transduction adaptor" Q99836 3 38138478-38143022 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 75.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 172.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB009104 Approved Supported Vesicles,Mitochondria,Cytosol NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "Vesicles, Mitochondria" "CAB009104: AB_2146724" "prognostic favorable (8.45e-4)" "unprognostic (1.19e-1)" "unprognostic (4.31e-2)" "unprognostic (2.51e-2)" "unprognostic (4.77e-2)" "unprognostic (4.38e-3)" "unprognostic (4.37e-2)" "unprognostic (3.63e-1)" "unprognostic (1.67e-1)" "unprognostic (7.28e-2)" "unprognostic (1.01e-2)" "unprognostic (7.30e-2)" "unprognostic (2.11e-2)" "unprognostic (4.41e-1)" "unprognostic (4.17e-2)" "unprognostic (1.65e-1)" "unprognostic (2.08e-2)" 20.1 14.2 6.9 43.5 7.4 51.8 15.0 7.2 7.5 15.2 8.0 30.3 32.2 12.1 18.6 36.6 14.4 23.5 9.4 6.7 7.7 13.7 61.1 42.6 35.2 9.5 7.5 11.4 11.6 11.6 9.2 22.6 8.0 14.3 31.7 2.1 18.0 12.0 3.2 17.7 32.2 24.5 8.6 40.7 27.6 7.7 9.2 38.3 9.4 8.8 41.6 47.4 20.3 8.5 25.1 34.2 5.9 33.2 25.0 32.0 10.8 23.6 39.0 68.1 72.9 22.7 30.9 52.8 13.8 44.7 15.8 30.9 43.2 24.2 22.1 39.5 8.7 28.5 16.6 36.6 21.4 36.2 72.0 38.4 26.6 39.2 15.3 13.2 39.9 40.3 13.3 22.3 36.8 25.7 61.3 12.2 22.1 52.8 35.7 24.8 7.0 23.1 37.6 58.9 3.0 12.0 33.4 172.1 22.3 4.8 25.8 40.8 35.5 13.8 7.9 60.6 24.0 28.9 32.9 38.5 25.0 63.0 28.9 288.5 236.9 296.9 67.2 333.6 58.1 43.7 60.6 69.3 203.6 35.2 42.1 59.5 284.7 54.6 436.1 99.9 87.4 257.3 6.9 7.4 7.2 7.5 6.7 7.7 9.5 7.5 8.0 8.6 9.2 8.5 13.4 6.4 15.2 2.0 19.5 14.4 13.5 12.7 14.2 1.0 11.3 10.8 1.6 5.7 16.4 5.5 0.0 14.6 35.3 40.8 7.9 24.5 1.4 10.9 30.2 15.9 9.6 9.7 0.2 27.3 24.4 10.8 23.9 18.6 24.1 10.0 10.4 33.2 32.2 0.0 0.4 14.9 10.2 75.4 40.5 0.9 13.7 61.5 3.6 1.9 58.1 4.1 28.8 2.5 0.3 64.0 34.8 10.5 12.9 16.0 28.0 12.2 12.1 0.1 13.1 4.3 7.2 8.6 0.6 15.1 17.2 12.0 19.6 10.2 15.9 49.4 MYEOV OCIM ENSG00000172927 "Myeloma overexpressed" Q96EZ4 11 69294151-69367726 "Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 5.4;breast: 5.3;esophagus: 9.6;stomach 1: 6.0" "Cell type enriched" "Detected in many" 5 "Pancreatic endocrine cells: 199.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 172.8;A549: 83.5;CAPAN-2: 24.3;U-2 OS: 36.1" HPA012949 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm Vesicles "HPA012949: AB_1854241" "unprognostic (1.42e-2)" "unprognostic (8.56e-2)" "unprognostic (7.07e-2)" "unprognostic (3.36e-1)" "unprognostic (5.60e-2)" "unprognostic (7.28e-3)" "unprognostic (7.58e-3)" "prognostic unfavorable (2.00e-4)" "unprognostic (3.49e-1)" "unprognostic (6.33e-2)" "prognostic unfavorable (1.54e-7)" "unprognostic (2.83e-1)" "prognostic unfavorable (1.48e-5)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (3.35e-1)" "unprognostic (3.69e-2)" 5.4 0.1 0.0 0.6 0.0 0.1 5.3 0.0 0.0 1.8 0.0 0.5 0.3 0.0 0.7 9.6 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.1 0.1 0.1 0.0 0.0 1.8 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.6 0.0 0.0 4.1 0.2 0.0 0.0 0.2 6.0 0.0 0.0 0.0 0.1 0.0 1.0 0.1 3.9 0.0 172.8 83.5 0.0 0.0 0.0 0.0 2.5 0.2 0.1 0.0 0.0 0.5 24.3 0.5 6.3 0.0 0.1 2.5 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.4 0.0 0.0 6.4 0.0 0.0 0.1 0.0 0.1 8.5 0.0 2.4 0.2 0.1 3.8 0.1 0.1 0.2 3.4 6.8 0.0 0.1 3.5 0.6 0.2 0.0 0.0 0.0 2.4 0.6 0.0 2.9 0.7 1.6 0.1 36.1 0.0 1.4 0.3 1.7 0.2 0.2 0.5 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 1.0 0.8 0.8 3.8 0.0 0.0 30.7 37.7 0.4 0.0 17.6 3.7 0.0 0.0 0.9 7.8 0.0 12.6 12.7 1.2 0.1 0.5 0.0 0.0 0.0 9.4 0.4 3.4 23.9 1.5 0.0 0.1 0.0 0.2 2.4 0.0 0.0 1.3 2.0 0.0 0.0 6.9 0.3 4.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 199.3 22.3 0.0 3.9 1.4 0.0 0.0 1.5 0.0 0.0 0.1 2.9 0.0 0.4 3.4 1.3 0.1 0.4 0.0 2.7 8.5 MYH15 KIAA1000 ENSG00000144821 "Myosin heavy chain 15" Q9Y2K3 3 108380368-108529322 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.9;retina: 2.8;tongue: 1.8" "Cell type enhanced" "Detected in some" "Astrocytes: 14.0;Excitatory neurons: 8.8;Inhibitory neurons: 6.3;Muller glia cells: 8.0;Oligodendrocyte precursor cells: 5.0;Oligodendrocytes: 10.6;Rod photoreceptor cells: 5.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 4.4;Karpas-707: 2.3;PC-3: 5.1;SH-SY5Y: 1.8;U-87 MG: 1.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA034871, HPA057915" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 24: B-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 5: Muller glia cells - Visual perception" Cytosol Vesicles "HPA034871: AB_10669996, HPA057915: " "unprognostic (4.37e-2)" "unprognostic (7.29e-2)" "unprognostic (2.08e-2)" "unprognostic (1.31e-3)" "unprognostic (2.62e-1)" "unprognostic (1.70e-1)" "unprognostic (2.96e-1)" "unprognostic (7.84e-3)" "unprognostic (7.32e-2)" "unprognostic (1.89e-2)" "unprognostic (5.67e-2)" "unprognostic (6.67e-2)" "unprognostic (4.42e-2)" "unprognostic (5.68e-2)" "unprognostic (5.43e-2)" "unprognostic (8.41e-2)" "unprognostic (3.57e-2)" 0.1 0.2 1.5 0.1 1.9 0.1 0.0 1.4 1.4 0.1 0.6 0.4 0.4 0.0 0.3 0.0 0.1 0.2 0.4 1.5 1.7 0.0 0.0 0.3 0.1 1.7 1.5 0.0 0.0 0.0 0.9 0.0 1.5 0.2 0.3 2.8 0.1 0.0 0.2 0.5 0.6 0.0 1.5 0.2 0.1 0.6 1.6 0.1 0.1 1.8 0.0 0.0 0.0 1.6 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.4 0.9 0.1 0.2 0.0 0.4 0.0 0.1 0.0 4.4 0.0 0.1 0.0 0.8 0.0 0.1 0.1 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.2 0.1 0.2 0.2 0.1 0.0 2.3 1.2 0.0 0.0 0.0 0.0 0.0 5.1 0.1 0.0 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.5 0.0 0.5 1.2 0.2 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 1.9 1.4 1.4 1.5 1.7 1.7 1.5 1.5 1.5 1.6 1.6 0.0 0.0 0.5 14.0 0.3 0.0 0.1 0.0 0.0 1.7 0.0 0.0 2.3 0.0 0.0 0.0 2.1 0.0 0.1 0.4 0.0 0.2 3.0 1.0 0.1 0.1 0.0 0.0 8.8 0.2 0.0 0.6 0.0 0.1 0.0 0.5 0.0 0.0 0.1 1.7 6.3 1.1 0.0 0.0 0.3 0.9 0.0 0.1 1.8 1.0 0.0 8.0 0.0 5.0 10.6 0.5 0.0 0.0 1.6 0.4 0.1 0.1 0.0 5.1 0.0 0.1 0.6 1.1 0.6 0.0 0.1 0.0 0.1 0.5 1.2 0.1 MYLK3 "caMLCK, MLCK" ENSG00000140795 "Myosin light chain kinase 3" Q32MK0 16 46702282-46790407 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "heart muscle: 103.4;skeletal muscle: 46.5;tongue: 72.6" "Group enriched" "Detected in some" 12 "Cardiomyocytes: 169.0;Endometrial ciliated cells: 44.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 12.9;HEL: 40.2;K-562: 6.5;SK-BR-3: 7.9" "Group enriched" "Detected in some" 7 "cerebral cortex: 9.6;hippocampal formation: 5.1" "Region enriched" "Detected in single" 5 "hippocampal formation: 3.5" HPA073447 Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm Vesicles "HPA073447: AB_2732225" "unprognostic (6.01e-4)" "unprognostic (2.19e-1)" "unprognostic (2.64e-1)" "unprognostic (1.77e-2)" "unprognostic (1.84e-1)" "unprognostic (2.94e-3)" "unprognostic (2.60e-1)" "unprognostic (4.73e-2)" "unprognostic (3.33e-2)" "unprognostic (2.41e-2)" "unprognostic (6.58e-3)" "unprognostic (1.83e-1)" "unprognostic (4.16e-2)" "unprognostic (2.57e-2)" "unprognostic (2.52e-1)" "unprognostic (1.08e-2)" "unprognostic (2.97e-1)" 0.0 0.1 1.9 0.1 1.7 0.3 0.1 1.1 2.3 0.4 1.7 0.0 0.1 0.3 0.8 4.3 1.7 0.2 103.4 2.5 2.8 1.1 0.1 0.4 0.2 9.8 12.2 0.3 0.1 0.0 0.4 0.5 8.2 2.2 0.1 0.2 2.1 0.1 46.5 0.1 0.1 0.2 5.9 0.1 0.1 6.0 1.9 0.1 0.1 72.6 0.1 0.0 0.0 3.0 0.0 0.1 0.1 0.1 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.8 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.2 2.0 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 6.5 0.3 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.4 0.0 7.9 0.2 3.5 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.5 0.1 0.3 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 1.9 1.7 1.1 2.3 2.5 2.8 9.8 12.2 8.2 5.9 1.9 3.0 0.2 0.0 3.3 0.7 0.5 0.0 0.7 0.0 0.0 0.9 1.3 0.0 169.0 0.0 3.7 0.0 2.1 2.0 0.2 0.0 0.0 0.0 8.1 44.8 7.1 1.7 0.0 0.0 0.9 0.2 0.5 6.7 0.0 2.2 1.3 1.6 0.7 0.1 0.4 0.0 0.6 0.0 0.0 0.0 0.0 7.2 0.6 0.8 0.0 0.0 0.2 0.8 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.8 0.0 0.2 8.7 1.3 0.0 4.9 2.7 1.0 0.7 0.0 0.0 0.3 0.8 0.7 0.0 0.8 MYLK4 SgK085 ENSG00000145949 "Myosin light chain kinase family member 4" Q86YV6 6 2663629-2750922 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "skeletal muscle: 30.1;tongue: 72.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 7.8;Inhibitory neurons: 7.2;Microglial cells: 4.7;Oligodendrocyte precursor cells: 8.0;Proximal tubular cells: 4.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HEL: 7.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA015860 Uncertain Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "Nucleoli, Vesicles" "HPA015860: AB_2147922" "unprognostic (1.75e-1)" "unprognostic (2.04e-1)" "unprognostic (1.87e-1)" "unprognostic (5.22e-3)" "unprognostic (1.85e-1)" "unprognostic (2.99e-2)" "unprognostic (7.48e-2)" "unprognostic (2.80e-1)" "unprognostic (5.32e-2)" "unprognostic (2.25e-1)" "unprognostic (2.02e-2)" "unprognostic (2.91e-1)" "unprognostic (2.74e-3)" "unprognostic (1.43e-1)" "unprognostic (2.65e-1)" "unprognostic (1.19e-2)" "unprognostic (4.63e-2)" 1.2 0.5 0.6 0.3 0.6 0.8 1.0 0.6 0.9 0.6 0.7 0.4 0.3 0.6 0.7 1.3 0.5 0.4 1.4 0.7 0.7 3.0 0.5 1.2 0.4 0.4 0.5 0.4 0.9 0.9 1.3 0.6 0.4 0.7 0.3 0.8 2.4 0.6 30.1 1.4 0.6 0.3 0.4 0.6 0.6 0.4 0.6 0.3 0.8 72.1 0.7 0.6 0.8 0.6 0.1 0.1 0.3 0.6 0.5 0.6 0.3 0.4 0.8 0.2 0.2 0.3 0.6 0.6 0.9 0.4 0.1 1.0 0.1 0.2 0.3 0.1 0.3 7.2 0.4 0.0 0.2 0.2 0.3 0.8 0.3 0.0 0.6 0.3 0.3 0.1 0.0 0.0 0.1 0.3 0.0 0.8 0.1 0.2 0.0 0.5 0.0 0.0 0.4 0.1 0.5 0.3 0.1 0.1 0.3 0.5 0.2 0.5 0.4 0.2 0.0 0.1 0.2 0.2 0.1 0.0 0.1 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.6 0.9 0.7 0.7 0.4 0.5 0.4 0.4 0.6 0.6 0.5 3.2 1.1 1.6 0.5 0.1 0.1 0.5 0.6 1.0 0.6 0.3 1.9 1.5 1.0 0.0 0.0 0.3 0.1 0.2 0.0 0.3 0.4 0.1 0.7 0.6 1.2 0.0 7.8 0.2 0.0 0.5 0.0 0.2 0.0 0.6 1.1 0.2 0.3 1.7 7.2 0.0 0.0 0.8 1.2 0.2 0.3 0.4 0.0 4.7 1.1 0.3 0.0 8.0 2.9 0.0 0.0 1.5 0.0 0.2 0.1 4.5 0.3 0.3 0.0 0.8 0.3 0.0 0.3 0.3 0.9 0.3 0.2 0.4 0.3 0.2 MYMX MINION ENSG00000262179 "Myomixer, myoblast fusion factor" A0A1B0GTQ4 6 44216926-44218234 "Predicted intracellular proteins" Myogenesis "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "adipose tissue: 7.7;breast: 6.9;pancreas: 5.6;stomach 1: 2.3" "Group enriched" "Detected in some" 4 "Adipocytes: 5.5;Distal tubular cells: 3.9;Exocrine glandular cells: 2.2;Extravillous trophoblasts: 1.6" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 106 "plasmacytoid DC: 10.6" "Lineage enriched" "Detected in single" 106 "dendritic cells: 10.6" "Cell line enriched" "Detected in some" 31 "RH-30: 134.6" "Not detected" "Not detected" HPA051451 Supported Approved Vesicles,Mitochondria,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Mitochondria, Cytosol" "HPA051451: " "unprognostic (1.24e-1)" "unprognostic (8.55e-2)" "unprognostic (6.86e-2)" "unprognostic (6.51e-3)" "unprognostic (2.78e-1)" "unprognostic (1.26e-1)" "unprognostic (5.27e-2)" "unprognostic (2.10e-3)" "unprognostic (4.32e-1)" "unprognostic (1.77e-1)" "unprognostic (8.71e-2)" "unprognostic (2.70e-2)" "unprognostic (2.01e-4)" "unprognostic (1.63e-2)" "unprognostic (1.33e-2)" "unprognostic (1.77e-2)" "unprognostic (2.67e-1)" 7.7 0.1 0.0 0.2 0.0 0.0 6.9 0.1 0.1 0.2 0.0 0.3 0.0 0.1 0.2 0.2 0.1 0.5 1.0 0.0 0.0 0.7 0.1 0.4 0.6 0.1 0.0 0.1 5.6 0.0 0.0 0.0 0.1 0.1 0.1 0.0 1.1 0.0 0.4 0.9 0.5 0.1 0.0 0.8 2.3 0.4 0.0 0.8 0.4 0.2 0.3 0.5 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.0 4.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 3.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 134.6 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 1.7 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 2.2 1.6 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 MYO16 "KIAA0865, Myo16b, MYR8, NYAP3, PPP1R107" ENSG00000041515 "Myosin XVI" Q9Y6X6 13 108596152-109208005 "Predicted intracellular proteins" "Actin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.4" "Group enriched" "Detected in some" 8 "Inhibitory neurons: 460.0;Oligodendrocyte precursor cells: 299.6" "Cancer enhanced" "Detected in some" "glioma: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.0;SH-SY5Y: 4.5;U-2197: 2.7" "Region enhanced" "Detected in all" "olfactory bulb: 72.6" "Low region specificity" "Detected in all" "HPA040110, HPA058769, HPA071948" Uncertain Approved Vesicles NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA040110: AB_10796339, HPA058769: AB_2683814, HPA071948: AB_2686475" "unprognostic (7.55e-3)" "unprognostic (7.74e-3)" "unprognostic (4.52e-4)" "unprognostic (5.12e-3)" "unprognostic (1.38e-1)" "unprognostic (5.81e-2)" "unprognostic (1.20e-2)" "unprognostic (2.16e-1)" "unprognostic (2.53e-1)" "unprognostic (6.50e-2)" "unprognostic (9.01e-3)" "unprognostic (5.29e-2)" "unprognostic (4.68e-4)" "unprognostic (4.26e-2)" "unprognostic (3.21e-2)" "unprognostic (7.06e-2)" "unprognostic (2.34e-2)" 1.4 0.7 2.5 0.2 4.9 0.0 0.2 1.2 3.7 0.2 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.9 5.4 1.8 0.0 1.9 0.2 0.2 0.6 1.5 0.0 0.1 0.0 1.7 0.1 2.3 0.2 0.1 0.4 0.1 0.7 0.0 0.1 0.0 0.4 2.6 0.0 0.0 1.1 2.6 0.0 0.0 0.2 0.3 0.0 0.2 0.9 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.7 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 4.9 1.2 3.7 5.4 1.8 0.6 1.5 2.3 2.6 2.6 0.9 1.0 0.0 0.6 19.6 0.0 0.3 0.0 0.4 0.0 4.2 0.1 0.3 3.7 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.5 11.3 0.5 1.1 0.1 0.0 3.4 44.6 0.0 0.1 0.8 0.0 0.3 1.3 0.1 0.0 5.9 0.1 0.0 460.0 0.0 0.0 0.0 0.3 11.4 0.9 0.1 1.8 8.4 0.0 2.8 0.0 299.6 4.7 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.4 0.0 0.1 0.1 5.0 7.7 0.0 0.0 0.3 0.3 1.6 0.0 0.0 MYOF "FER1L3, KIAA1207" ENSG00000138119 Myoferlin Q9NZM1 10 93306429-93482334 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 123.4;Pancreatic endocrine cells: 153.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 20.4;non-classical monocyte: 26.6" "Group enriched" "Detected in many" 57 "dendritic cells: 8.1;monocytes: 26.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 452.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014245 Enhanced Supported "Vesicles,Plasma membrane" NA NA 190000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "Plasma membrane" "HPA014245: AB_1848495" "unprognostic (3.41e-2)" "unprognostic (3.85e-1)" "unprognostic (2.88e-2)" "unprognostic (7.44e-2)" "unprognostic (3.50e-2)" "unprognostic (8.57e-3)" "unprognostic (3.48e-2)" "unprognostic (7.75e-2)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.55e-1)" "unprognostic (5.74e-3)" "unprognostic (1.87e-1)" "unprognostic (1.94e-2)" "unprognostic (9.17e-2)" "unprognostic (9.18e-2)" 31.7 8.1 2.9 20.6 4.1 1.5 43.3 5.0 2.5 56.4 37.4 22.4 5.3 27.5 7.1 36.4 36.9 26.6 13.8 3.4 4.1 10.9 2.9 32.2 4.4 8.9 6.8 9.8 5.9 23.8 3.8 55.2 8.1 27.5 29.3 0.9 19.7 31.4 3.6 56.1 9.0 44.3 6.2 6.5 13.4 2.2 5.4 5.1 35.7 6.2 9.1 62.0 29.4 6.2 228.9 206.3 21.4 14.6 159.4 318.4 62.0 190.3 452.7 110.1 109.2 51.1 177.1 0.0 76.9 353.7 116.2 350.0 1.8 204.7 82.6 1.4 0.9 0.0 80.8 2.1 55.2 0.0 0.2 183.0 71.6 77.7 323.8 289.4 299.7 0.0 0.0 0.5 275.6 39.4 0.1 0.9 1.6 72.0 171.6 0.0 15.8 0.1 314.3 281.5 0.1 0.0 130.4 29.7 46.1 83.1 141.5 4.7 378.5 167.3 11.8 111.3 113.9 0.2 0.3 0.3 128.2 2.6 201.0 0.0 5.4 0.0 0.0 20.4 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.3 0.0 26.6 2.8 0.2 1.6 2.9 4.1 5.0 2.5 3.4 4.1 8.9 6.8 8.1 6.2 5.4 6.2 42.5 60.9 52.5 1.6 1.2 23.7 63.0 101.4 39.3 0.1 48.4 34.3 9.2 14.3 91.5 22.0 0.0 56.6 3.8 74.1 1.9 54.8 0.6 50.9 45.9 28.8 1.8 0.0 2.7 33.7 23.7 38.1 23.0 123.4 1.3 1.7 35.7 0.4 22.9 0.0 0.8 29.6 42.7 29.2 20.2 0.6 5.9 28.5 8.8 60.0 12.8 0.1 0.0 2.0 0.7 153.7 22.2 9.1 0.8 86.7 0.6 1.5 60.7 0.8 6.6 15.9 39.6 0.1 0.3 53.4 30.7 51.2 1.9 8.3 18.7 100.7 MYOM3 FLJ35961 ENSG00000142661 "Myomesin 3" Q5VTT5 1 24056035-24112135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "heart muscle: 222.5;skeletal muscle: 321.5;tongue: 255.9" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 198.3" "Cancer enhanced" "Detected in some" "renal cancer: 6.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A549: 4.6;Hep G2: 18.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA028132, HPA028340" Approved "Golgi apparatus,Vesicles,Cytokinetic bridge" Yes No 830000 "Cluster 38: Heart - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 54: Cardiomyocytes - Muscle contraction" Vesicles "Golgi apparatus, Cytokinetic bridge" "HPA028132: AB_10599293, HPA028340: " "unprognostic (8.59e-2)" "unprognostic (2.85e-2)" "unprognostic (2.39e-1)" "unprognostic (8.60e-3)" "unprognostic (1.52e-2)" "unprognostic (7.31e-2)" "unprognostic (3.00e-2)" "unprognostic (1.40e-2)" "unprognostic (4.66e-1)" "unprognostic (2.21e-1)" "unprognostic (2.73e-4)" "unprognostic (2.09e-1)" "prognostic favorable (4.28e-6)" "unprognostic (2.77e-2)" "unprognostic (1.60e-3)" "unprognostic (7.75e-2)" "unprognostic (1.68e-1)" 0.4 0.2 0.0 0.2 0.0 0.0 0.7 0.3 0.1 0.2 0.0 0.6 1.1 0.3 0.0 6.0 0.9 0.4 222.5 0.1 0.1 31.4 0.2 0.3 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.0 0.1 4.5 0.7 1.2 7.1 0.0 321.5 2.2 5.2 0.2 0.0 0.0 0.2 9.0 0.0 1.7 0.3 255.9 0.1 0.1 0.4 0.2 0.1 4.6 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 1.3 0.0 1.9 0.6 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.8 18.1 0.0 0.1 0.1 0.5 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.2 0.2 0.1 1.0 0.2 0.5 0.6 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.0 0.6 0.2 0.1 0.6 0.0 0.1 0.6 198.3 0.0 0.0 3.7 0.0 0.0 0.1 3.6 1.9 0.1 16.2 0.4 0.0 1.6 1.2 0.0 0.4 0.4 0.0 6.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.3 1.7 0.0 0.0 0.7 10.3 0.6 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.2 2.5 2.4 0.0 0.0 0.2 13.0 33.2 0.0 2.5 6.6 10.0 1.3 0.0 0.2 0.0 0.6 0.0 0.3 2.3 2.2 0.3 MYPN MYOP ENSG00000138347 Myopalladin Q86TC9 10 68106117-68212017 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Cardiomyopathy, Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 64.1;skeletal muscle: 283.6;tongue: 172.8" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 114.2" "Cancer enriched" "Detected in single" 7 "head and neck cancer: 0.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "basophil: 1.4" "Lineage enriched" "Detected in single" 14 "granulocytes: 1.4" "Cell line enhanced" "Detected in many" "BJ: 39.8;fHDF/TERT166: 112.3;HBF TERT88: 25.6;LHCN-M2: 47.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA036299, HPA061494" Enhanced Approved Nucleoplasm,Vesicles,Cytosol No No "Cluster 41: Basophils - Cellular respiration" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Vesicles" Cytosol "HPA036299: , HPA061494: AB_2684539" "unprognostic (4.75e-2)" "unprognostic (2.20e-1)" "unprognostic (8.14e-3)" "unprognostic (8.62e-3)" "unprognostic (3.91e-1)" "unprognostic (3.36e-3)" "unprognostic (4.62e-2)" "unprognostic (3.86e-2)" "unprognostic (2.82e-1)" "unprognostic (2.26e-3)" "unprognostic (3.94e-3)" "unprognostic (3.10e-1)" "unprognostic (2.88e-8)" "unprognostic (4.63e-5)" "unprognostic (9.94e-2)" "unprognostic (2.01e-1)" "unprognostic (3.47e-1)" 0.1 0.3 0.2 0.2 0.1 0.6 0.1 0.5 0.2 0.0 0.0 0.3 0.1 0.1 0.1 2.2 0.0 0.1 64.1 0.8 0.8 0.0 0.0 0.0 0.2 0.6 0.2 0.1 0.6 0.0 0.0 0.1 0.1 1.7 0.1 1.7 2.7 0.0 283.6 0.1 0.1 0.2 0.0 0.1 0.8 0.9 0.0 0.1 0.0 172.8 0.0 0.1 0.0 0.3 2.9 1.3 0.0 0.0 0.7 4.1 0.1 39.8 19.7 14.4 5.4 0.0 0.1 0.1 0.0 112.3 20.5 0.7 0.0 0.2 25.6 0.4 0.0 0.0 14.6 0.0 0.3 0.0 0.1 1.6 0.0 7.9 0.9 3.6 0.4 0.0 0.0 0.2 47.6 8.6 0.0 0.1 0.0 0.0 1.3 0.0 2.2 0.0 0.1 0.1 0.1 0.0 5.7 0.9 0.2 0.1 0.0 0.0 1.1 0.7 0.2 4.1 0.1 0.1 0.0 0.0 4.6 0.1 4.2 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.5 0.2 0.8 0.8 0.6 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 2.6 0.2 0.0 114.2 0.0 0.0 0.0 25.0 0.0 0.0 1.8 0.0 0.0 1.0 1.5 0.1 0.7 0.0 0.0 0.5 0.2 0.0 1.8 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.0 0.4 0.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.1 MYT1L "KIAA1106, NZF1, ZC2H2C2, ZC2HC4B" ENSG00000186487 "Myelin transcription factor 1 like" Q9UL68 2 1789113-2331664 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Autism spectrum disorder, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 45.8;pituitary gland: 14.8" "Group enriched" "Detected in many" 4 "Excitatory neurons: 582.4;Inhibitory neurons: 635.5;Oligodendrocyte precursor cells: 265.4" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebral cortex: 45.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "SCLC-21H: 18.6;SH-SY5Y: 7.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060245 Approved Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA060245: AB_2732643" "unprognostic (9.90e-3)" "unprognostic (3.74e-1)" "unprognostic (1.30e-1)" "unprognostic (9.61e-3)" "unprognostic (7.17e-2)" "unprognostic (3.73e-2)" "unprognostic (2.44e-1)" "unprognostic (2.36e-2)" "unprognostic (3.21e-2)" "unprognostic (1.93e-2)" "unprognostic (2.46e-1)" "unprognostic (7.96e-2)" "unprognostic (1.21e-2)" "unprognostic (1.04e-2)" 0.0 1.4 7.8 0.2 14.1 0.1 0.0 4.2 45.8 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 17.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.0 14.8 0.1 0.0 0.1 0.1 5.4 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.2 5.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 15.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 18.6 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.0 0.1 0.0 0.1 7.8 14.1 4.2 45.8 17.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.1 6.4 6.1 16.6 0.0 1.8 0.5 0.0 0.0 46.7 0.5 0.4 4.5 0.0 3.1 1.8 2.1 0.1 0.2 0.1 0.0 0.0 5.0 0.4 0.1 1.3 0.0 0.0 582.4 0.0 0.2 1.3 0.0 0.2 6.3 0.1 0.7 0.4 0.1 117.8 635.5 0.0 0.0 0.6 0.8 4.7 0.0 0.8 0.0 18.7 0.0 1.5 0.0 265.4 11.1 0.1 0.0 1.5 0.1 0.4 0.0 0.2 1.5 7.4 6.6 1.5 0.4 50.0 31.4 0.0 1.0 0.3 0.9 0.1 0.0 0.6 NACC1 "BEND8, BTBD14B, BTBD30, NAC-1, NAC1" ENSG00000160877 "Nucleus accumbens associated 1" Q96RE7 19 13116862-13141147 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021238, HPA062245, CAB069927" Enhanced Enhanced Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 47: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Vesicles "CAB069927: AB_1082966, HPA021238: AB_1845475, HPA062245: AB_2684724" "unprognostic (2.19e-1)" "unprognostic (9.20e-3)" "unprognostic (2.67e-2)" "unprognostic (2.84e-2)" "unprognostic (2.62e-1)" "unprognostic (7.75e-2)" "unprognostic (8.46e-3)" "unprognostic (1.10e-1)" "unprognostic (1.93e-1)" "unprognostic (8.46e-2)" "unprognostic (2.40e-2)" "unprognostic (3.04e-2)" "unprognostic (7.35e-2)" "unprognostic (2.80e-2)" "unprognostic (1.02e-1)" "unprognostic (1.97e-1)" "unprognostic (9.74e-2)" 12.6 19.5 31.0 14.6 19.2 8.8 10.3 7.1 26.6 9.7 0.0 17.3 13.3 18.4 7.9 27.6 11.9 6.4 20.9 25.7 7.4 14.8 20.5 16.7 12.1 13.4 15.9 7.7 12.2 10.7 14.8 12.4 15.1 14.6 6.6 3.7 15.8 11.2 24.2 17.4 16.0 7.7 8.9 15.9 16.0 17.0 20.6 11.3 14.0 7.9 8.8 15.0 12.6 16.4 98.8 110.0 28.0 59.6 15.0 17.7 74.9 47.4 34.2 42.4 32.4 114.8 40.4 50.9 104.1 39.8 37.3 49.0 34.8 80.7 16.2 89.1 52.5 32.4 87.9 84.7 35.5 52.0 82.3 28.8 28.0 46.1 24.7 36.5 50.2 46.4 72.5 19.8 22.9 206.1 82.9 39.6 123.6 28.9 101.7 47.8 32.9 49.5 28.2 101.1 58.2 37.7 49.6 64.9 39.1 29.8 59.3 46.4 76.7 94.6 58.8 67.2 87.0 53.4 88.1 42.4 99.7 52.8 58.9 0.0 0.2 0.0 0.2 0.1 0.1 0.1 0.3 0.1 0.1 0.0 0.2 0.1 0.3 0.0 0.1 0.2 0.1 0.1 31.0 19.2 7.1 26.6 25.7 7.4 13.4 15.9 15.1 8.9 20.6 16.4 4.9 0.0 1.7 6.2 5.6 12.1 7.5 11.8 2.8 16.6 11.5 7.5 2.1 12.8 8.5 16.5 2.1 19.0 12.9 22.7 7.9 12.3 2.3 10.9 8.9 8.1 4.9 12.2 7.2 8.8 20.0 5.2 10.7 17.6 10.2 13.3 8.6 18.0 21.1 26.9 5.9 16.2 14.2 9.6 9.6 2.0 4.4 8.8 5.4 3.7 10.5 12.0 10.3 5.5 5.4 21.7 11.1 9.4 5.6 16.5 14.0 15.0 5.9 7.7 6.6 7.5 7.0 11.1 15.6 8.4 13.9 27.1 7.9 15.2 15.4 17.2 NADK FLJ13052 ENSG00000008130 "NAD kinase" O95544 1 1751232-1780457 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 506.2" "Group enriched" "Detected in all" 7 "granulocytes: 506.2;monocytes: 162.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048909, HPA053368" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm Vesicles "HPA048909: AB_2680553, HPA053368: AB_2682130" "unprognostic (1.29e-1)" "unprognostic (4.29e-1)" "unprognostic (7.07e-2)" "unprognostic (6.82e-2)" "unprognostic (1.98e-1)" "unprognostic (1.58e-2)" "unprognostic (3.32e-1)" "unprognostic (9.03e-2)" "unprognostic (7.81e-2)" "unprognostic (1.11e-1)" "unprognostic (1.49e-1)" "unprognostic (1.68e-1)" "unprognostic (4.54e-3)" "unprognostic (1.40e-1)" "unprognostic (5.36e-2)" "unprognostic (1.50e-2)" "unprognostic (1.16e-1)" 53.6 81.8 24.8 37.5 26.6 100.7 44.7 22.1 29.0 28.6 27.8 45.1 38.0 30.9 13.3 29.9 36.1 23.3 28.7 24.1 24.3 30.2 134.0 40.3 41.2 25.4 24.6 37.2 38.9 17.2 26.4 26.0 25.0 32.9 25.4 10.9 40.2 17.4 19.6 28.3 43.3 19.8 24.5 93.1 43.2 27.5 26.5 16.4 31.7 19.2 26.6 32.3 27.1 23.8 41.6 39.3 34.4 50.7 47.8 34.5 44.2 40.9 35.5 45.6 40.3 42.1 74.2 54.5 30.4 30.5 14.7 34.6 37.3 32.5 20.3 53.5 59.1 44.7 65.0 73.6 46.2 63.4 72.1 40.6 28.9 28.4 40.3 24.8 44.9 42.6 55.9 75.8 34.4 47.4 48.1 54.8 23.5 69.4 43.8 60.4 29.4 113.1 39.7 33.9 46.2 35.2 45.8 99.2 43.7 20.3 34.2 43.6 43.8 33.1 23.7 34.6 37.5 67.1 32.7 121.8 32.7 69.3 17.6 84.2 141.3 329.7 7.4 158.6 8.8 10.8 4.3 5.9 45.9 12.1 2.8 4.1 506.2 3.8 162.6 37.9 7.0 82.9 24.8 26.6 22.1 29.0 24.1 24.3 25.4 24.6 25.0 24.5 26.5 23.8 29.0 12.8 30.7 14.4 27.2 9.8 15.7 11.2 13.6 7.9 21.4 17.9 6.8 25.8 21.6 14.7 16.7 24.5 46.8 57.8 15.6 19.1 14.9 18.7 22.2 20.8 22.8 15.8 10.2 29.4 26.3 18.7 52.0 22.8 2.5 21.2 22.5 94.3 36.6 6.7 10.4 38.7 16.2 58.4 13.7 26.7 37.6 45.0 8.8 9.4 67.3 5.7 27.8 10.6 11.1 28.7 34.6 34.6 26.0 34.7 28.6 24.3 13.5 17.7 13.1 12.6 18.2 12.4 22.4 19.5 12.8 42.8 15.4 44.2 31.0 27.5 NADSYN1 FLJ10631 ENSG00000172890 "NAD synthetase 1" Q6IA69 11 71453109-71524107 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017798, HPA038523, HPA038524" Approved Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 45: Enterocytes - Digestion" Vesicles "Golgi apparatus, Cytosol" "CAB017798: , HPA038523: AB_2676060, HPA038524: AB_2676061" "unprognostic (1.45e-1)" "unprognostic (1.29e-1)" "unprognostic (7.30e-2)" "unprognostic (2.63e-3)" "unprognostic (1.75e-1)" "unprognostic (1.60e-1)" "prognostic unfavorable (5.17e-6)" "unprognostic (1.19e-2)" "unprognostic (4.38e-2)" "unprognostic (1.41e-1)" "unprognostic (9.41e-2)" "unprognostic (1.99e-2)" "prognostic unfavorable (8.72e-5)" "unprognostic (4.12e-3)" "unprognostic (1.38e-1)" "unprognostic (1.54e-2)" "prognostic favorable (5.10e-4)" 29.5 34.1 18.8 24.1 20.4 67.6 26.2 18.5 21.2 30.4 20.3 48.6 39.5 26.0 24.2 56.3 31.2 25.8 20.3 17.8 18.3 33.2 49.8 35.3 33.3 22.4 19.6 27.6 29.5 13.4 36.0 16.5 21.0 45.3 36.0 6.9 32.9 22.8 11.0 31.1 51.1 19.3 18.8 58.4 34.3 25.6 21.7 27.9 31.8 5.1 28.2 43.4 33.4 24.4 15.9 37.8 12.0 21.6 35.0 50.6 32.4 29.7 27.2 15.4 17.0 32.4 25.7 13.4 33.1 35.3 20.7 55.2 15.9 42.6 8.2 27.9 12.8 22.2 27.6 36.3 43.3 45.1 40.9 72.0 65.8 19.9 17.8 34.9 54.6 24.2 11.9 18.5 21.9 49.7 22.4 29.9 7.0 69.6 21.3 27.5 37.2 13.5 37.8 72.1 8.9 12.7 21.2 27.9 56.0 17.9 24.9 24.4 66.2 16.7 14.2 30.9 11.8 24.3 11.0 11.7 29.9 25.6 12.0 6.1 28.0 17.3 15.3 25.0 12.7 12.2 13.5 13.8 31.1 9.2 8.8 11.4 17.7 16.3 22.6 23.0 17.7 21.4 18.8 20.4 18.5 21.2 17.8 18.3 22.4 19.6 21.0 18.8 21.7 24.4 12.6 22.4 32.3 4.2 24.0 6.2 17.8 18.4 26.2 7.8 13.5 10.9 8.3 12.8 19.8 11.0 4.2 17.4 27.3 65.3 3.9 16.5 22.6 21.1 11.1 15.6 23.4 20.2 5.1 17.3 14.5 12.8 51.0 19.7 22.1 23.1 13.9 16.7 20.1 13.5 5.8 30.3 16.2 23.2 18.5 60.9 9.3 25.4 8.8 8.4 25.8 5.9 29.9 7.5 18.5 20.0 55.8 10.1 18.0 17.9 73.3 16.2 16.5 7.3 13.1 9.6 9.8 15.9 5.0 38.3 12.8 17.2 22.3 17.1 43.7 24.2 NANOG "FLJ12581, FLJ40451" ENSG00000111704 "Nanog homeobox" Q9H9S0 12 7787794-7799146 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.9" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 8.4;Spermatocytes: 5.5" "Cancer enriched" "Detected in single" 1164 "testis cancer: 58.1" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 1.7" "Group enriched" "Detected in many" 5 "dendritic cells: 1.7;granulocytes: 1.5" "Cell line enriched" "Detected in some" 5 "NTERA-2: 125.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB019380, HPA072117" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 5: NTERA-2 - Transcription" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Vesicles "CAB019380: , HPA072117: " "unprognostic (1.76e-1)" "unprognostic (1.86e-1)" "unprognostic (1.01e-1)" "unprognostic (1.78e-1)" "unprognostic (8.59e-3)" "unprognostic (3.50e-1)" "unprognostic (3.46e-2)" "unprognostic (6.35e-2)" "unprognostic (1.10e-1)" "unprognostic (3.87e-1)" "unprognostic (4.51e-7)" "unprognostic (3.46e-2)" "unprognostic (2.09e-1)" "unprognostic (1.51e-1)" "unprognostic (3.85e-2)" 0.0 0.1 0.3 0.1 0.7 0.4 0.1 1.9 0.4 0.0 0.3 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.0 0.2 0.4 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.3 0.3 0.0 0.1 0.1 0.2 0.2 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 125.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 1.5 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.3 0.2 0.2 0.7 0.3 0.2 1.7 0.1 0.0 0.3 0.7 1.9 0.4 0.3 0.1 0.3 0.1 0.3 0.1 0.4 0.7 0.4 0.0 0.0 0.0 0.2 1.7 1.8 0.8 0.0 2.2 0.3 0.1 0.8 0.0 0.3 0.0 8.4 1.6 1.4 0.1 0.0 0.4 1.0 0.3 0.5 0.6 0.0 0.0 0.0 0.4 0.2 0.4 0.0 0.3 0.0 2.1 0.7 0.6 0.5 0.0 0.0 0.3 2.0 0.3 0.0 0.3 1.5 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.1 0.2 0.4 1.5 0.0 0.9 0.0 0.3 0.9 1.0 0.0 1.7 0.4 5.5 0.6 0.0 0.6 0.7 0.7 0.7 0.4 1.8 NANOGP8 ENSG00000255192 "Nanog homeobox retrogene P8" Q6NSW7 15 35083410-35085295 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "brain: 3.7" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 415 "testis cancer: 20.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 69 "NTERA-2: 33.2;SuSa: 11.6" HPA072117 Supported Nucleoplasm,Vesicles NA NA "Cluster 6: Brain - Smell perception" "Cluster 5: NTERA-2 - Transcription" Nucleoplasm Vesicles "HPA072117: " "unprognostic (1.58e-1)" "unprognostic (9.05e-3)" "unprognostic (1.48e-1)" "unprognostic (2.37e-1)" 0.1 0.1 0.7 0.0 3.7 0.2 0.1 2.1 1.8 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.1 0.2 0.5 0.2 0.1 0.1 0.0 0.3 0.2 0.2 0.2 0.0 0.2 0.0 0.4 0.2 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.7 1.2 0.0 0.1 0.0 0.0 0.1 0.1 0.6 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 33.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.7 3.7 2.1 1.8 0.2 0.5 0.3 0.2 0.4 0.2 1.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NAP1L3 "MB20, MGC26312, NPL3" ENSG00000186310 "Nucleosome assembly protein 1 like 3" Q99457 X 93670930-93673578 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 103.4;retina: 40.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 41.8;Excitatory neurons: 27.9;Horizontal cells: 62.2;Inhibitory neurons: 57.1" "Cancer enhanced" "Detected in many" "glioma: 12.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 4.1" "Group enriched" "Detected in many" 25 "NK-cells: 3.1;T-cells: 4.1" "Cell line enhanced" "Detected in some" "AF22: 13.6;HAP1: 13.2;NTERA-2: 24.0;SuSa: 20.7;U-2197: 16.1" "Low region specificity" "Detected in all" HPA026075 Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA026075: AB_1854301" "unprognostic (7.18e-2)" "unprognostic (1.81e-2)" "unprognostic (9.26e-2)" "unprognostic (4.83e-4)" "unprognostic (3.06e-1)" "unprognostic (1.28e-2)" "unprognostic (5.10e-2)" "unprognostic (1.76e-1)" "unprognostic (3.31e-2)" "unprognostic (9.29e-2)" "unprognostic (2.75e-3)" "unprognostic (5.01e-2)" "unprognostic (2.75e-3)" "unprognostic (5.78e-3)" "unprognostic (1.19e-1)" "unprognostic (1.75e-1)" "unprognostic (5.23e-4)" 2.5 13.4 65.2 2.8 53.3 1.2 2.6 46.9 103.4 19.3 11.2 3.2 1.5 12.1 5.6 1.3 10.0 5.4 11.3 50.5 62.9 3.3 1.3 1.8 2.5 45.3 62.7 16.7 1.3 1.0 18.1 1.5 54.4 4.4 2.4 40.9 1.4 5.3 0.4 1.7 2.0 8.2 40.6 4.6 1.4 16.6 46.9 1.1 5.6 1.2 1.3 3.5 2.8 47.5 0.0 0.2 13.6 9.9 0.2 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 2.0 7.6 0.3 0.1 13.2 0.0 0.0 0.0 0.3 6.4 0.0 0.2 0.7 0.0 0.4 6.1 0.0 0.6 6.2 0.0 0.0 6.8 0.0 0.0 0.7 0.0 0.0 0.0 24.0 0.0 5.7 0.0 10.5 0.0 0.4 0.1 0.1 1.4 0.0 0.0 0.2 20.7 0.0 0.7 0.0 7.5 10.9 16.1 0.7 10.2 4.5 0.0 4.2 0.0 0.1 0.0 0.0 0.0 1.9 0.0 0.7 0.0 2.6 0.9 0.0 0.0 4.1 2.9 0.1 3.1 0.0 0.0 0.8 0.9 65.2 53.3 46.9 103.4 50.5 62.9 45.3 62.7 54.4 40.6 46.9 47.5 0.8 0.0 0.0 11.8 0.3 0.6 0.3 0.0 0.0 41.8 0.2 1.9 8.3 0.0 0.6 0.0 6.2 0.2 0.8 0.0 17.6 0.1 1.2 0.3 9.9 1.4 0.0 1.3 27.9 0.0 0.2 7.6 0.0 0.3 5.7 7.4 1.1 0.0 0.4 62.2 57.1 0.0 0.0 0.0 0.9 2.2 11.8 0.3 5.4 9.4 0.2 16.6 0.0 16.6 21.2 0.2 0.0 19.5 0.1 0.0 0.0 0.5 1.5 12.9 0.0 6.6 4.0 5.7 7.4 0.0 0.4 0.3 1.6 16.4 0.0 0.0 NAXE "AIBP, APOA1BP, MGC119143, MGC119144, MGC119145, YJEFN1" ENSG00000163382 "NAD(P)HX epimerase" Q8NCW5 1 156591756-156609507 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Lipid transport, Transport" Isomerase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 136.7;Distal tubular cells: 201.5;Ductal cells: 112.8;Exocrine glandular cells: 100.1;Proximal tubular cells: 219.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043766, HPA048164" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 3300000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Vesicles, Cytosol" "HPA043766: AB_2678660, HPA048164: AB_2680294" "unprognostic (1.27e-1)" "unprognostic (2.34e-2)" "unprognostic (2.49e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (7.38e-2)" "unprognostic (5.32e-2)" "unprognostic (2.46e-3)" "unprognostic (2.60e-1)" "unprognostic (1.72e-1)" "unprognostic (3.08e-3)" "unprognostic (3.23e-2)" "unprognostic (3.14e-2)" "unprognostic (2.15e-2)" "unprognostic (8.05e-2)" "unprognostic (7.43e-2)" "unprognostic (2.09e-1)" "unprognostic (3.81e-1)" 47.1 74.8 61.0 20.9 63.7 22.2 47.9 66.1 69.6 56.8 71.1 62.9 45.5 68.8 88.7 58.0 59.5 26.5 111.1 60.9 64.3 83.8 86.5 43.6 27.0 62.7 64.8 46.5 69.7 104.7 70.0 23.7 61.8 62.5 41.6 17.4 53.9 48.3 71.8 55.8 48.3 39.7 64.7 43.2 67.5 40.8 63.5 30.6 59.8 68.2 34.3 55.0 47.8 70.5 114.2 155.4 43.9 84.4 64.0 43.8 55.5 29.5 62.3 69.5 72.6 130.6 76.8 62.4 113.4 52.5 55.9 111.1 49.4 99.0 47.5 81.2 98.5 58.1 76.2 86.1 75.1 60.0 60.9 44.2 123.7 87.9 81.9 53.4 95.4 104.7 54.7 70.1 71.6 209.6 83.3 98.0 43.1 158.1 118.2 87.7 40.2 212.6 93.0 93.6 114.7 102.9 90.4 172.4 141.6 66.4 178.3 117.5 51.1 45.1 64.8 64.6 70.6 180.1 110.3 53.0 63.1 37.0 70.4 25.4 96.3 52.9 121.2 111.3 121.3 236.2 109.4 124.3 89.1 186.5 122.8 114.9 11.4 141.3 89.1 225.7 110.1 186.6 61.0 63.7 66.1 69.6 60.9 64.3 62.7 64.8 61.8 64.7 63.5 70.5 29.5 41.7 32.9 0.0 14.8 0.0 0.0 0.0 0.0 0.0 87.5 96.0 0.0 0.0 23.5 68.0 0.0 136.7 28.7 0.0 201.5 112.8 0.0 27.3 29.9 18.4 0.0 0.0 0.0 100.1 43.1 27.2 0.0 32.0 5.1 53.5 0.0 0.0 92.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 40.8 0.0 0.0 0.0 0.0 91.0 0.0 0.0 6.2 0.0 0.0 219.6 11.7 0.0 0.0 0.0 24.5 0.0 0.0 0.0 0.0 81.3 13.4 48.1 0.0 0.0 NBR1 "1A1-3B, CA125, KIAA0049, M17S2" ENSG00000188554 "NBR1 autophagy cargo receptor" Q14596 17 43170481-43211689 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 276.9;Late spermatids: 909.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022944, HPA022999, HPA023999" Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "Nucleoplasm, Nuclear bodies" "HPA022944: AB_2671001, HPA022999: AB_1859532, HPA023999: AB_1859533" "unprognostic (1.85e-1)" "unprognostic (1.78e-1)" "unprognostic (3.26e-2)" "unprognostic (3.28e-2)" "unprognostic (3.27e-1)" "unprognostic (1.58e-1)" "unprognostic (1.15e-1)" "unprognostic (2.98e-1)" "unprognostic (2.18e-1)" "unprognostic (1.02e-2)" "unprognostic (1.03e-1)" "unprognostic (1.54e-2)" "prognostic favorable (2.00e-5)" "unprognostic (1.65e-1)" "unprognostic (4.88e-2)" "unprognostic (2.10e-1)" "unprognostic (1.39e-1)" 45.7 52.3 48.4 39.4 54.5 20.1 55.9 52.1 48.2 52.0 51.2 66.2 70.1 48.9 39.9 40.3 53.4 44.5 67.3 43.7 49.9 84.7 91.3 47.3 41.0 52.2 50.4 69.7 43.9 97.1 28.8 60.1 52.9 64.7 70.4 80.1 49.4 52.0 112.2 42.9 73.8 49.3 52.1 53.0 52.6 141.0 51.6 59.0 68.2 116.0 45.4 47.3 34.5 65.2 42.3 49.8 42.6 44.6 93.5 95.2 41.0 77.1 147.2 60.5 50.4 26.6 65.1 22.7 77.8 105.1 62.6 46.1 48.5 97.4 90.3 70.0 51.2 27.1 62.0 60.0 89.4 23.2 40.1 108.4 111.6 67.2 133.7 127.3 96.0 50.8 58.1 58.7 83.7 23.9 48.9 17.7 13.6 50.0 32.8 16.5 65.6 73.3 81.6 48.0 25.9 45.8 53.1 26.1 79.8 70.7 70.7 38.0 82.2 89.9 34.1 42.7 31.5 69.9 61.8 29.1 61.8 31.5 63.6 41.6 25.7 40.1 20.3 23.3 20.7 13.7 18.1 19.6 19.3 9.4 17.0 16.6 34.4 24.3 36.4 12.0 26.4 25.0 48.4 54.5 52.1 48.2 43.7 49.9 52.2 50.4 52.9 52.1 51.6 65.2 36.9 41.7 44.1 24.5 21.9 23.8 29.2 28.1 54.1 37.3 33.8 27.4 86.4 35.8 40.4 36.8 39.6 28.0 34.6 94.2 19.6 25.4 276.9 40.5 30.4 39.0 40.2 53.2 24.7 21.9 19.4 37.6 31.1 33.0 25.9 53.1 45.3 67.8 22.0 20.2 28.2 56.4 20.3 62.9 19.9 909.9 58.7 35.7 26.6 29.0 35.6 49.3 44.3 33.2 41.4 25.8 64.5 44.4 26.1 41.1 100.3 57.4 63.4 56.9 39.5 33.9 36.2 49.6 30.9 26.7 27.3 15.7 31.9 68.6 52.4 38.7 NDFIP2 "KIAA1165, N4wbp5a" ENSG00000102471 "Nedd4 family interacting protein 2" Q9NV92 13 79481124-79556075 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 342.7;Late spermatids: 290.4;Suprabasal keratinocytes: 367.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 12.1;eosinophil: 22.7;naive CD4 T-cell: 5.6" "Group enriched" "Detected in many" 16 "granulocytes: 22.7;T-cells: 5.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009160 Uncertain Supported Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" Vesicles "HPA009160: AB_1079456" "unprognostic (2.56e-1)" "unprognostic (5.51e-3)" "unprognostic (1.95e-3)" "unprognostic (9.61e-2)" "unprognostic (2.60e-1)" "prognostic unfavorable (5.99e-4)" "unprognostic (1.50e-1)" "unprognostic (5.53e-2)" "unprognostic (2.30e-1)" "unprognostic (3.12e-1)" "unprognostic (1.52e-2)" "unprognostic (2.63e-2)" "prognostic favorable (4.18e-5)" "unprognostic (1.32e-1)" "unprognostic (1.31e-1)" "unprognostic (6.47e-2)" "unprognostic (1.02e-1)" 13.9 19.2 17.0 11.4 20.9 2.6 22.7 10.0 25.2 15.5 7.0 42.7 52.7 10.1 22.5 54.4 17.1 20.1 26.0 27.1 8.1 45.9 46.3 17.7 13.0 10.1 7.3 7.0 31.8 29.6 6.4 31.9 12.3 22.7 47.0 21.7 21.4 15.6 30.9 71.3 64.3 9.1 10.6 11.7 25.9 18.1 9.2 16.0 19.3 19.9 19.6 35.6 25.2 21.5 134.6 22.6 23.2 29.4 27.7 50.3 43.6 48.5 66.9 50.1 83.0 49.9 146.1 5.6 32.6 64.0 28.5 178.2 20.5 84.9 75.3 69.7 57.1 6.2 66.5 27.1 50.5 106.2 17.8 40.4 109.3 33.4 52.7 55.8 24.1 10.4 27.5 10.0 56.8 19.3 8.7 24.1 17.1 109.7 22.7 0.5 45.7 25.2 123.1 76.7 23.3 33.4 54.9 52.4 40.0 37.8 43.8 88.2 20.4 16.0 20.4 31.1 32.8 37.6 44.2 21.1 65.6 0.5 65.6 12.1 0.0 22.7 3.2 0.0 2.7 0.2 2.8 2.6 0.0 0.6 5.6 3.1 0.1 0.8 0.0 0.2 3.2 2.4 17.0 20.9 10.0 25.2 27.1 8.1 10.1 7.3 12.3 10.6 9.2 21.5 17.5 41.7 28.9 26.4 4.4 342.7 137.0 180.6 118.4 30.9 32.7 18.8 29.4 57.2 93.2 47.8 6.2 112.6 6.9 161.0 23.5 85.6 271.2 51.5 17.2 22.0 69.4 4.2 189.0 72.2 152.7 33.2 31.1 49.8 88.2 11.5 20.7 69.2 14.4 16.8 44.2 88.1 95.6 17.0 23.5 290.4 17.4 4.0 33.8 27.2 2.7 22.8 5.2 42.3 100.3 101.7 96.7 12.8 13.8 105.6 204.3 104.6 112.6 15.5 13.1 22.2 24.0 56.5 45.1 102.2 367.7 109.7 24.9 35.2 73.3 145.5 NDNF "C4orf31, FLJ23191" ENSG00000173376 "Neuron derived neurotrophic factor" Q8TB73 4 121035613-121073021 "Disease related genes, Predicted secreted proteins" Neurogenesis "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 106.5;placenta: 60.1;retina: 57.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 246.8;Bipolar cells: 69.8;Early spermatids: 217.1;Late spermatids: 221.7" "Cancer enriched" "Detected in many" 4 "lung cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 48.5;U-266/70: 20.8;U-266/84: 85.8" "Group enriched" "Detected in all" 4 "basal ganglia: 11.1;olfactory bulb: 34.0" "Low region specificity" "Detected in all" HPA048881 Supported Vesicles "Secreted in other tissues" NA NA "Cluster 19: Lung - Lung function" "Cluster 16: U-266 - Nucleosome" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA048881: " "unprognostic (2.84e-1)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (1.04e-1)" "unprognostic (3.94e-1)" "unprognostic (6.26e-2)" "unprognostic (2.22e-1)" "unprognostic (2.93e-2)" "unprognostic (6.65e-4)" "unprognostic (2.18e-3)" "unprognostic (6.27e-2)" "unprognostic (3.44e-2)" "prognostic unfavorable (3.26e-4)" "unprognostic (2.38e-3)" "unprognostic (1.20e-1)" "unprognostic (1.18e-4)" "unprognostic (1.74e-1)" 4.8 2.6 1.1 0.9 1.7 0.0 3.2 4.7 1.2 14.2 9.3 6.5 2.9 6.0 4.3 7.7 20.4 9.4 5.2 1.8 2.6 27.1 0.4 106.5 0.3 8.8 12.9 42.5 0.5 0.7 5.3 60.1 15.2 16.7 8.3 57.4 2.2 4.4 4.3 1.7 4.7 3.5 7.6 0.3 4.1 10.4 3.7 2.4 1.3 14.0 0.2 9.0 1.9 5.4 0.2 0.0 10.6 0.0 13.9 11.3 0.2 0.2 0.5 0.2 0.5 1.6 0.0 0.0 0.0 48.5 0.8 0.0 0.0 0.0 1.1 0.9 1.7 0.0 0.0 0.0 0.0 0.1 0.0 2.7 0.0 0.0 0.2 0.6 0.0 0.0 0.0 14.3 1.0 0.0 0.2 0.1 0.9 7.4 2.1 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 2.6 0.2 0.0 0.0 11.5 0.0 0.2 0.5 20.8 85.8 0.0 3.9 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.7 4.7 1.2 1.8 2.6 8.8 12.9 15.2 7.6 3.7 5.4 10.9 246.8 48.3 1.6 0.0 1.1 0.0 0.0 0.0 69.8 0.2 0.1 1.6 8.6 28.6 12.9 18.8 0.3 0.0 5.3 0.0 0.0 217.1 0.9 4.7 11.7 1.8 0.0 0.0 0.2 0.0 14.9 0.0 0.1 2.5 0.1 2.9 0.0 0.1 1.7 8.0 0.8 0.0 0.0 0.8 221.7 3.4 0.4 5.4 6.5 0.0 12.2 0.0 0.0 0.0 0.1 0.5 0.7 0.0 0.0 0.0 0.0 12.5 20.0 0.0 1.2 3.6 6.4 5.0 0.3 0.9 0.5 0.3 13.0 1.2 0.1 NDP "EVR2, norrin" ENSG00000124479 "Norrin cystine knot growth factor NDP" Q00604 X 43948776-43973395 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision, Wnt signaling pathway" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.8;ovary: 46.2" "Group enriched" "Detected in some" 4 "Granulosa cells: 181.3;Muller glia cells: 105.5" "Cancer enriched" "Detected in many" 5 "glioma: 25.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "U-87 MG: 72.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003095 Supported Nucleoplasm,Nucleoli,Vesicles "Secreted to extracellular matrix" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Nucleoplasm, Nucleoli" "HPA003095: AB_1079457" "unprognostic (1.12e-1)" "unprognostic (7.12e-2)" "unprognostic (2.27e-2)" "unprognostic (2.55e-3)" "unprognostic (6.84e-3)" "unprognostic (1.51e-1)" "unprognostic (9.09e-2)" "unprognostic (2.29e-1)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" "unprognostic (1.40e-1)" "unprognostic (3.02e-2)" "unprognostic (2.22e-2)" "unprognostic (1.47e-1)" "unprognostic (1.13e-1)" "unprognostic (2.87e-3)" 0.5 0.0 31.5 0.0 33.4 0.0 3.3 30.9 35.8 20.9 22.4 0.2 0.1 15.4 22.0 0.0 20.8 0.4 0.3 31.5 29.6 0.1 0.0 0.0 0.2 30.1 33.2 46.2 0.0 0.2 0.1 4.0 31.6 7.1 0.2 19.2 0.1 13.1 0.0 0.6 0.2 11.4 32.4 0.1 0.3 1.0 34.2 0.0 0.2 0.0 0.2 0.5 2.3 32.4 0.0 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 1.5 0.0 0.0 0.1 1.9 0.0 0.0 0.0 1.8 0.0 4.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.2 0.0 0.0 2.2 0.0 0.0 0.0 72.9 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.5 33.4 30.9 35.8 31.5 29.6 30.1 33.2 31.6 32.4 34.2 32.4 0.0 0.0 0.0 29.0 0.0 0.1 0.0 1.2 0.0 0.6 1.3 0.1 0.3 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 2.0 0.0 9.1 17.7 0.2 0.0 0.0 4.2 0.0 0.3 0.9 0.0 17.0 0.0 181.3 0.0 0.0 0.1 0.0 0.8 0.0 2.0 0.0 0.0 0.7 13.4 0.6 0.0 0.0 0.0 105.5 0.0 1.5 9.5 1.2 0.0 9.8 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 5.4 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 NECAP1 DKFZP566B183 ENSG00000089818 "NECAP endocytosis associated 1" Q8NC96 12 8076939-8097881 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" Epilepsy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053980, HPA063300" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 21: OE19 - Mitochondria" "Cluster 52: Non-specific - Transcription" Vesicles Cytosol "HPA053980: AB_2682331, HPA063300: AB_2684981" "unprognostic (1.73e-2)" "unprognostic (6.11e-2)" "unprognostic (2.01e-1)" "unprognostic (2.25e-1)" "unprognostic (4.87e-1)" "unprognostic (1.06e-3)" "unprognostic (1.03e-1)" "unprognostic (1.22e-1)" "unprognostic (4.56e-1)" "unprognostic (5.79e-3)" "unprognostic (5.72e-3)" "unprognostic (1.03e-1)" "unprognostic (1.72e-2)" "unprognostic (1.89e-2)" "unprognostic (2.64e-1)" "unprognostic (2.06e-1)" "unprognostic (5.94e-2)" 11.7 23.7 25.4 11.8 23.2 8.0 13.6 19.3 39.6 14.9 1.0 17.8 15.6 10.2 8.7 12.1 15.5 9.9 12.7 25.5 44.0 15.8 14.4 11.2 8.0 13.0 11.1 16.1 22.3 27.5 24.7 15.9 17.8 15.7 16.9 42.5 15.9 12.4 7.9 9.4 15.6 11.4 13.8 10.1 16.1 13.6 15.2 14.2 12.6 12.2 10.4 16.9 10.1 15.9 20.4 18.8 12.6 17.6 29.6 22.0 28.2 41.8 26.6 36.1 36.2 40.9 23.1 9.2 7.3 20.9 26.2 14.0 35.2 23.1 31.2 28.2 27.4 11.6 21.2 21.4 26.9 10.7 29.2 28.7 26.3 40.4 48.0 27.7 26.2 15.0 27.3 14.8 38.8 25.8 17.3 2.8 35.1 57.2 15.4 6.8 32.0 9.7 24.6 32.0 20.7 14.3 21.3 29.7 15.9 40.7 10.1 8.9 26.6 16.9 33.3 20.3 30.1 9.4 18.4 19.9 30.6 11.7 26.0 28.8 16.6 36.4 10.9 15.7 12.7 9.8 10.3 11.2 11.9 10.2 12.1 11.0 28.7 10.6 22.7 7.2 16.8 13.0 25.4 23.2 19.3 39.6 25.5 44.0 13.0 11.1 17.8 13.8 15.2 15.9 18.9 38.5 24.0 11.4 36.1 25.5 22.0 16.0 25.6 49.0 17.5 10.5 10.4 7.2 18.7 23.9 27.1 14.6 32.9 19.8 25.4 15.3 25.4 11.3 20.9 18.1 16.2 17.0 29.4 16.7 14.5 17.9 17.3 16.1 29.2 33.5 15.4 15.2 13.8 28.6 28.4 16.1 12.2 19.8 39.0 13.7 23.3 22.4 28.4 11.2 14.8 30.7 20.6 14.6 21.3 19.0 16.0 14.7 33.7 21.8 23.9 17.8 13.1 46.3 6.6 17.7 21.3 17.4 22.3 21.0 21.3 22.4 35.6 25.2 14.1 22.0 NEGR1 "IGLON4, KILON, MGC46680, Ntra" ENSG00000172260 "Neuronal growth regulator 1" Q7Z3B1 1 71395943-72282539 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 29.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 1968.8;Inhibitory neurons: 1254.4;Oligodendrocyte precursor cells: 726.3;Oligodendrocytes: 442.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 26.7;TIME: 28.5;U-2 OS: 22.9;U-251 MG: 24.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011894 Uncertain Approved "Vesicles,Actin filaments,Cytosol" NA NA 380000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Actin filaments, Cytosol" "HPA011894: AB_1854363" "unprognostic (2.60e-1)" "unprognostic (1.89e-2)" "unprognostic (1.23e-1)" "unprognostic (1.44e-1)" "unprognostic (7.99e-2)" "unprognostic (2.48e-1)" "unprognostic (3.72e-1)" "unprognostic (6.94e-2)" "unprognostic (8.15e-2)" "unprognostic (8.73e-2)" "unprognostic (3.38e-2)" "unprognostic (1.36e-1)" "unprognostic (3.31e-5)" "unprognostic (5.89e-3)" "unprognostic (1.31e-1)" "unprognostic (1.43e-3)" "unprognostic (2.11e-4)" 16.5 5.8 12.8 3.6 15.9 1.2 5.9 4.4 15.7 7.1 0.0 17.5 2.7 5.2 4.1 10.5 7.2 10.7 11.2 15.1 9.1 6.8 0.3 5.5 1.6 1.9 5.6 6.0 4.5 0.7 3.9 2.9 2.7 7.3 7.8 29.8 2.4 5.4 3.3 5.8 5.1 6.4 3.7 0.6 7.4 3.2 12.4 5.6 3.5 5.1 0.8 13.3 6.6 6.5 0.4 0.1 0.8 0.2 26.7 21.0 0.2 19.4 7.2 10.4 12.7 0.1 0.2 0.3 0.1 21.5 0.2 0.6 0.0 0.0 22.4 0.2 0.1 0.1 3.4 0.1 2.2 0.2 0.4 10.2 0.1 8.9 1.5 15.4 12.5 0.3 0.1 0.8 19.5 0.1 0.2 0.2 3.2 0.3 11.0 13.7 20.4 0.3 1.7 0.3 1.5 1.7 6.8 0.1 0.0 0.4 0.1 0.3 28.5 2.3 22.9 0.9 24.5 0.4 0.2 0.1 5.2 13.0 8.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 12.8 15.9 4.4 15.7 15.1 9.1 1.9 5.6 2.7 3.7 12.4 6.5 6.0 0.0 0.5 170.7 0.0 5.0 0.6 0.1 0.0 51.4 0.2 0.5 4.2 1.5 2.5 0.0 27.1 0.0 4.4 0.1 0.0 2.4 6.2 0.1 1.3 2.6 0.0 0.8 1968.8 0.0 0.0 88.7 0.5 0.1 0.0 0.2 0.0 0.0 0.2 1.7 1254.4 0.6 0.0 0.0 16.7 12.5 210.3 2.4 8.8 58.1 3.1 12.2 0.0 726.3 442.7 0.5 0.0 44.8 0.5 1.3 0.0 1.5 7.1 58.7 32.9 8.3 8.5 0.7 2.5 0.3 3.4 0.0 1.1 0.2 0.1 0.7 NEIL2 "FLJ31644, MGC2832, MGC4505, NEH2" ENSG00000154328 "Nei like DNA glycosylase 2" Q969S2 8 11769639-11787345 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Glycosidase, Hydrolase, Lyase, Multifunctional enzyme" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatogonia: 68.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA073029, HPA073916" Supported Nucleoplasm,Vesicles NA NA "Cluster 30: Non-specific - Translation" "Cluster 35: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm Vesicles "HPA073029: AB_2732216, HPA073916: AB_2732245" "unprognostic (1.52e-2)" "unprognostic (1.08e-2)" "unprognostic (1.03e-1)" "unprognostic (9.88e-2)" "unprognostic (2.18e-2)" "unprognostic (5.72e-2)" "unprognostic (2.70e-1)" "unprognostic (2.88e-2)" "unprognostic (5.46e-2)" "unprognostic (6.85e-2)" "unprognostic (1.99e-3)" "unprognostic (1.29e-1)" "unprognostic (1.12e-2)" "unprognostic (5.29e-2)" "unprognostic (1.91e-1)" "unprognostic (2.09e-1)" "unprognostic (4.05e-1)" 9.5 27.8 29.2 5.9 28.8 2.3 9.5 27.7 27.9 13.1 23.8 8.6 2.8 9.5 12.5 6.9 15.0 5.7 14.6 29.6 35.6 12.8 16.3 7.4 7.1 32.0 34.3 11.1 11.2 9.0 17.9 6.4 36.8 11.3 4.8 13.4 10.0 8.1 24.5 15.8 6.8 8.5 31.9 12.4 6.9 26.1 36.1 4.7 11.8 13.7 6.9 9.8 8.8 28.3 8.2 22.9 14.1 27.7 6.6 12.2 6.3 13.0 10.6 12.2 8.4 7.1 8.8 3.2 4.9 15.7 26.3 7.1 13.5 14.1 16.7 9.7 6.7 11.3 5.7 13.9 5.3 5.0 8.2 10.8 20.7 10.7 9.9 11.8 11.6 3.7 16.1 10.8 15.0 8.6 0.9 5.2 12.6 33.9 12.1 14.4 18.1 8.8 14.4 12.3 21.5 17.0 10.2 5.3 19.1 11.2 8.4 0.7 14.3 13.9 19.8 3.8 18.4 10.0 22.3 5.7 36.6 16.7 28.8 0.7 2.2 0.2 12.7 3.9 17.5 21.9 12.9 15.3 4.6 16.9 18.7 16.8 1.3 15.1 2.0 8.3 9.3 7.0 29.2 28.8 27.7 27.9 29.6 35.6 32.0 34.3 36.8 31.9 36.1 28.3 7.2 0.0 5.8 6.2 14.0 8.5 17.1 8.0 13.6 32.3 13.1 7.7 19.6 14.3 7.0 7.3 16.7 18.6 5.6 1.5 33.2 21.1 1.1 6.9 8.4 8.9 10.1 10.3 6.3 23.3 15.8 10.3 3.1 3.8 2.5 14.9 7.9 23.6 15.1 8.4 6.9 6.1 14.2 6.9 6.6 2.1 14.0 6.8 14.2 0.0 6.6 38.9 11.3 6.0 3.7 15.1 1.0 24.5 3.8 15.3 0.8 32.2 6.8 17.1 6.6 11.8 10.2 19.0 68.1 8.3 12.8 5.3 9.7 8.9 6.2 12.0 NEK10 FLJ32685 ENSG00000163491 "NIMA related kinase 10" Q6ZWH5 3 27110085-27369460 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 36.6;tongue: 20.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 87.6;Early spermatids: 123.5;Endometrial ciliated cells: 59.3;Excitatory neurons: 131.4;Inhibitory neurons: 130.2;Late spermatids: 61.7;Respiratory ciliated cells: 104.2" "Cancer enriched" "Detected in single" 5 "breast cancer: 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 6.0;LHCN-M2: 8.2;U-2 OS: 6.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA038941 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Vesicles Nucleoplasm "HPA038941: AB_10673600" "prognostic favorable (4.20e-4)" "unprognostic (2.17e-1)" "unprognostic (8.78e-2)" "unprognostic (2.15e-2)" "unprognostic (3.37e-2)" "unprognostic (3.02e-1)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (1.26e-1)" "unprognostic (1.93e-2)" "unprognostic (2.20e-3)" "unprognostic (1.37e-1)" "unprognostic (7.67e-2)" "unprognostic (1.33e-2)" "unprognostic (1.38e-2)" "unprognostic (1.57e-3)" "unprognostic (2.14e-1)" 0.2 0.3 3.0 0.3 5.3 0.3 14.0 0.0 9.4 1.4 3.3 2.0 2.5 0.8 8.3 1.8 11.0 1.4 3.3 9.6 5.0 1.7 2.5 2.4 0.5 3.3 5.7 0.7 0.7 0.4 3.4 0.1 2.7 1.7 0.5 6.2 0.3 1.2 12.4 0.3 0.8 0.3 2.3 0.4 1.0 36.6 6.1 0.5 0.7 20.0 0.6 1.2 0.2 0.9 0.8 1.6 0.8 0.9 0.6 1.5 0.3 6.0 0.9 1.6 1.4 0.0 0.4 0.5 1.4 2.5 1.1 0.1 0.4 0.4 1.7 1.1 0.6 0.1 3.4 2.9 0.1 0.3 0.8 1.8 0.4 2.5 0.1 2.0 1.1 3.4 0.1 0.6 8.2 0.1 0.6 0.4 0.5 0.2 0.2 0.8 0.3 0.2 3.0 0.5 0.1 0.2 0.9 0.3 0.4 0.5 4.8 0.3 0.7 4.3 6.8 0.2 0.6 0.2 0.2 0.4 3.6 0.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 3.0 5.3 0.0 9.4 9.6 5.0 3.3 5.7 2.7 2.3 6.1 0.9 1.5 6.4 0.0 11.4 0.3 0.3 0.3 3.2 0.0 14.5 25.8 7.4 12.9 4.3 9.3 1.8 87.6 0.0 0.8 0.2 0.0 0.4 123.5 59.3 1.3 2.4 0.0 0.0 131.4 0.0 0.3 3.1 0.0 7.7 0.0 1.1 0.7 1.3 0.2 0.0 130.2 0.4 12.2 1.0 0.8 61.7 1.8 1.1 0.0 32.8 0.1 1.0 1.0 20.6 12.9 0.2 2.7 1.2 0.1 1.9 2.1 0.3 104.2 19.1 0.0 14.9 2.4 32.2 2.2 0.1 0.4 0.0 1.1 3.7 0.6 0.4 NELFCD "HSPC130, NELF-C, NELF-D, TH1, TH1L" ENSG00000101158 "Negative elongation factor complex member C/D" Q8IXH7 20 58981208-58995133 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050641, HPA066262, HPA074936" Enhanced Supported "Nucleoplasm,Nuclear bodies,Vesicles,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nuclear bodies" "Vesicles, Cytosol" "HPA050641: AB_2681198, HPA066262: AB_2685644, HPA074936: " "unprognostic (1.70e-2)" "unprognostic (1.27e-1)" "unprognostic (2.60e-1)" "prognostic unfavorable (4.98e-5)" "unprognostic (6.20e-2)" "unprognostic (2.42e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (1.47e-1)" "unprognostic (3.58e-1)" "unprognostic (1.02e-1)" "unprognostic (6.07e-3)" "prognostic unfavorable (3.37e-4)" "unprognostic (4.62e-2)" "unprognostic (2.96e-1)" "unprognostic (9.88e-2)" "unprognostic (1.34e-1)" "unprognostic (2.59e-1)" 18.9 29.5 20.5 17.7 22.8 23.8 24.5 21.7 23.4 20.7 21.2 18.2 19.3 18.2 16.3 32.9 24.4 16.2 16.9 19.6 21.0 31.7 31.2 14.7 26.4 21.2 20.9 25.2 21.2 30.7 31.8 25.6 21.8 20.4 17.9 31.9 30.0 17.1 29.4 25.9 19.6 14.1 20.8 20.7 19.3 27.9 21.5 31.5 28.5 20.5 27.9 22.6 22.7 24.3 54.7 57.6 68.5 71.9 22.5 38.9 49.6 42.4 38.8 117.1 66.8 189.6 70.7 68.3 64.0 39.8 60.8 89.1 90.1 98.0 94.8 22.4 64.1 90.5 72.4 150.5 26.7 64.2 60.1 40.9 34.3 44.2 32.8 32.8 68.3 54.0 118.1 51.8 53.3 198.2 135.6 95.4 40.3 151.5 122.9 78.4 56.6 121.1 49.0 76.5 75.9 112.6 126.0 148.3 85.9 38.2 157.5 75.0 30.2 91.6 88.8 36.3 67.7 44.4 80.0 71.1 53.7 57.3 80.6 20.0 44.6 22.9 42.0 51.5 50.0 48.6 39.7 51.2 64.9 44.5 37.7 40.1 5.6 47.1 68.8 33.0 39.7 49.0 20.5 22.8 21.7 23.4 19.6 21.0 21.2 20.9 21.8 20.8 21.5 24.3 23.0 9.6 27.6 18.3 50.5 30.2 62.6 43.8 40.9 67.3 32.7 34.2 10.9 47.1 24.3 22.0 41.7 133.1 35.5 14.5 50.9 57.0 18.8 26.2 33.3 26.7 23.4 60.0 23.0 31.4 69.2 26.2 26.5 27.4 16.5 50.9 23.2 24.1 36.9 55.5 22.8 21.9 26.4 15.3 24.0 32.1 37.0 24.0 26.6 10.3 48.1 52.9 49.4 21.1 23.6 34.9 14.4 26.4 37.4 37.8 27.8 49.9 15.0 61.5 39.5 31.6 34.2 63.1 94.9 40.5 31.4 103.0 48.5 43.9 36.2 52.8 NELL2 NRP2 ENSG00000184613 "Neural EGFL like 2" Q99435 12 44508275-44921848 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 105.5;choroid plexus: 59.5;fallopian tube: 60.1;retina: 85.2" "Cell type enriched" "Detected in many" 6 "Excitatory neurons: 652.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 33.3" "Group enriched" "Detected in many" 15 "amygdala: 48.9;basal ganglia: 60.0;cerebral cortex: 105.5;hippocampal formation: 89.6;white matter: 42.0" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 70.4;naive CD8 T-cell: 111.1" "Lineage enriched" "Detected in many" 10 "T-cells: 111.1" "Cell line enhanced" "Detected in some" "AF22: 104.6;HEK 293: 27.5;NTERA-2: 41.2;SCLC-21H: 75.6;U-266/70: 27.5;U-266/84: 29.5;U-698: 40.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035714, HPA035715" Uncertain Approved Vesicles "Secreted to blood" NA NA 6400000 "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA035714: AB_2674746, HPA035715: AB_10669602" "unprognostic (4.25e-3)" "unprognostic (4.27e-2)" "unprognostic (1.06e-1)" "unprognostic (3.10e-2)" "unprognostic (3.01e-2)" "unprognostic (7.18e-2)" "unprognostic (5.85e-2)" "unprognostic (2.59e-2)" "unprognostic (4.85e-2)" "unprognostic (2.80e-1)" "prognostic favorable (5.56e-4)" "unprognostic (1.19e-1)" "unprognostic (1.71e-5)" "unprognostic (8.45e-2)" "unprognostic (2.92e-1)" "unprognostic (3.60e-3)" "unprognostic (3.75e-2)" 4.6 16.9 48.9 10.9 60.0 7.3 1.9 1.3 105.5 23.1 59.5 2.0 26.3 2.2 0.4 1.2 60.1 1.9 0.4 89.6 4.5 1.2 1.0 5.0 20.7 0.0 0.0 0.8 0.9 0.2 34.6 0.3 0.0 27.2 2.1 85.2 1.4 2.0 0.3 13.4 15.3 2.8 0.0 6.2 2.9 3.0 0.8 8.7 6.5 0.6 15.7 4.1 4.2 42.0 0.3 0.1 104.6 3.5 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.4 0.0 8.3 12.4 0.0 0.0 0.2 25.3 0.2 0.0 0.0 27.5 0.4 8.7 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.1 0.1 1.6 0.2 0.4 0.0 0.4 0.2 0.4 41.2 0.0 14.0 0.2 12.7 0.2 0.0 0.0 75.6 1.8 0.0 0.4 0.0 1.3 0.1 0.7 0.0 0.4 3.8 0.1 2.1 27.5 29.5 40.3 0.2 0.2 0.4 0.2 0.2 0.0 5.0 0.1 24.9 0.2 30.3 52.9 0.1 0.1 70.4 111.1 0.5 11.0 0.1 0.1 0.4 26.7 48.9 60.0 1.3 105.5 89.6 4.5 0.0 0.0 0.0 0.0 0.8 42.0 0.3 0.0 1.3 48.0 1.0 1.1 0.0 0.0 5.7 35.4 0.4 0.6 0.5 2.8 6.2 0.0 33.3 0.1 2.5 5.8 0.0 0.0 0.4 0.7 0.8 0.7 0.0 0.0 652.4 0.2 0.3 3.7 0.0 0.3 0.0 49.4 0.0 0.0 0.1 1.7 108.4 0.9 0.0 0.0 1.5 1.0 0.0 0.4 0.0 18.7 1.3 7.9 1.0 74.4 16.5 0.4 0.4 0.4 0.5 0.3 18.5 0.2 21.9 58.3 0.0 4.1 4.6 1.9 4.2 0.2 1.1 0.1 23.4 0.1 2.9 0.1 NET1 "ARHGEF8, NET1A" ENSG00000173848 "Neuroepithelial cell transforming 1" Q7Z628 10 5412557-5459056 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 242.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 8.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 252.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020068 Uncertain Approved Nucleoplasm,Vesicles Yes Yes "Cluster 32: T-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA020068: AB_2670348" "unprognostic (1.77e-2)" "unprognostic (1.87e-1)" "unprognostic (3.40e-1)" "unprognostic (4.05e-2)" "unprognostic (3.37e-3)" "unprognostic (2.15e-1)" "prognostic unfavorable (3.87e-5)" "unprognostic (6.31e-2)" "unprognostic (1.87e-1)" "unprognostic (2.77e-2)" "prognostic unfavorable (8.27e-4)" "unprognostic (2.26e-1)" "unprognostic (5.41e-2)" "unprognostic (1.20e-1)" "unprognostic (1.90e-1)" "unprognostic (3.01e-1)" "unprognostic (2.46e-1)" 48.8 10.8 35.5 23.4 34.2 40.5 52.8 38.5 57.6 43.7 52.8 92.2 56.2 41.8 56.2 68.4 46.2 35.9 13.2 30.2 32.4 49.3 45.1 22.2 26.7 41.8 37.2 28.5 37.9 5.4 10.6 65.7 43.8 41.3 88.2 6.5 93.1 24.3 25.0 39.8 74.7 36.9 37.5 8.1 77.8 14.4 41.1 30.4 26.2 28.0 33.0 60.8 59.3 40.1 115.9 67.7 45.2 51.0 26.8 11.9 252.9 69.1 37.6 53.4 50.4 36.4 215.2 40.6 27.7 42.4 11.4 185.5 54.9 104.3 63.9 38.1 38.5 77.5 22.9 84.0 7.2 21.5 31.1 18.2 61.0 54.0 12.3 47.6 31.1 42.6 138.5 64.4 30.0 54.3 74.3 30.6 61.5 158.6 51.0 45.0 85.0 32.4 33.4 57.6 38.5 20.6 60.7 110.9 20.3 76.2 36.7 65.3 29.5 20.3 30.9 30.7 56.0 39.3 23.1 53.4 18.1 33.1 43.4 2.0 0.6 1.4 0.6 1.0 0.0 1.4 1.2 0.4 4.9 0.6 8.7 1.7 0.1 0.8 0.4 2.0 4.0 2.2 35.5 34.2 38.5 57.6 30.2 32.4 41.8 37.2 43.8 37.5 41.1 40.1 18.4 32.1 55.8 2.6 12.7 40.3 127.2 49.0 103.0 11.0 52.6 28.3 12.1 41.5 84.3 12.9 4.2 110.2 8.4 242.2 5.9 13.1 2.4 97.7 30.6 42.7 80.8 54.1 5.1 24.4 109.1 33.2 107.0 131.4 15.2 16.9 12.5 55.7 14.5 3.3 7.7 145.3 34.6 10.5 59.8 2.4 21.8 31.2 35.6 44.0 48.7 3.8 0.0 8.5 5.7 62.1 148.3 87.6 39.2 67.8 123.6 29.2 85.7 3.5 111.7 183.0 185.0 26.3 16.0 158.1 32.4 117.5 9.3 2.9 145.0 186.5 NEU1 NEU ENSG00000204386 "Neuraminidase 1" Q99519 6 31857659-31862905 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 197.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 3.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.0" "Cell line enhanced" "Detected in some" "GAMG: 5.4;U-266/84: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015634, HPA021506" Approved Supported "Vesicles,Cell Junctions" NA NA 180000 "Cluster 1: Neutrophils - Mixed function" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 7: Non-specific - Mitochondria" Vesicles "Cell Junctions" "HPA015634: AB_1854386, HPA021506: AB_1854385" "unprognostic (3.84e-2)" "unprognostic (7.47e-2)" "unprognostic (9.64e-2)" "unprognostic (4.65e-2)" "unprognostic (3.00e-1)" "unprognostic (4.42e-3)" "unprognostic (1.38e-3)" "unprognostic (8.58e-3)" "unprognostic (7.49e-2)" "unprognostic (5.21e-2)" "unprognostic (4.44e-3)" "unprognostic (1.27e-1)" "unprognostic (2.70e-2)" "unprognostic (6.22e-2)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (2.13e-3)" 23.9 57.2 0.7 0.4 0.8 0.0 22.4 2.5 1.2 21.2 1.2 25.1 0.7 19.5 0.0 14.9 16.8 1.0 22.5 0.7 0.6 43.7 29.9 28.9 0.3 0.8 0.5 20.3 35.9 0.3 33.0 0.2 0.8 26.5 0.0 1.6 38.6 0.0 21.3 20.1 24.3 0.1 0.3 25.3 29.8 8.2 1.0 0.0 31.8 0.0 0.0 23.2 16.2 1.7 0.3 0.2 0.8 1.4 1.8 0.4 0.7 0.2 0.2 0.3 0.3 1.5 0.6 0.7 0.4 0.1 5.4 0.3 2.2 0.0 0.4 2.5 0.3 0.6 0.9 1.2 1.4 0.9 1.8 1.0 0.2 1.4 0.7 0.2 0.6 0.9 1.1 1.2 0.5 0.3 0.6 0.0 0.6 0.5 0.4 0.9 0.4 0.9 1.0 0.4 0.7 0.4 0.2 0.3 0.7 0.9 0.9 0.5 0.7 1.1 0.8 0.7 0.6 3.7 9.6 0.9 1.7 0.4 0.4 1.3 0.3 0.4 0.2 0.3 0.1 0.2 0.2 0.1 0.2 0.6 0.2 0.3 3.0 0.3 0.2 0.3 0.2 0.1 0.7 0.8 2.5 1.2 0.7 0.6 0.8 0.5 0.8 0.3 1.0 1.7 65.7 25.6 46.3 5.2 57.0 34.3 48.5 45.0 39.9 26.4 87.7 55.8 29.0 51.5 54.8 47.8 25.0 62.8 100.5 83.7 9.8 114.2 0.8 29.3 53.5 42.8 113.5 4.6 6.3 59.6 57.8 73.8 32.6 60.8 67.9 17.4 30.7 34.5 170.9 10.1 7.6 39.9 79.3 63.0 65.9 1.4 27.7 93.0 71.2 9.4 25.8 48.8 9.2 5.0 4.0 34.4 88.1 23.3 81.7 89.0 115.0 59.9 29.2 32.7 26.3 60.8 43.7 5.4 10.0 29.3 41.6 197.0 81.7 40.3 41.1 34.6 NEU3 ENSG00000162139 "Neuraminidase 3" Q9UQ49 11 74988279-75018893 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 62.6;Spermatocytes: 32.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038729, HPA070381" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 34: Basophils - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Vesicles "HPA038729: AB_2676179, HPA070381: " "unprognostic (1.67e-1)" "unprognostic (2.10e-1)" "unprognostic (2.55e-2)" "unprognostic (1.13e-3)" "unprognostic (2.95e-2)" "unprognostic (5.42e-2)" "unprognostic (1.63e-1)" "unprognostic (5.11e-2)" "unprognostic (3.91e-3)" "unprognostic (8.50e-2)" "prognostic favorable (5.98e-4)" "unprognostic (3.57e-3)" "unprognostic (3.80e-2)" "unprognostic (3.79e-1)" "unprognostic (2.38e-1)" "unprognostic (3.73e-1)" "unprognostic (1.84e-1)" 3.2 12.7 8.1 6.4 9.7 23.7 6.5 5.1 10.8 3.8 2.9 4.2 4.3 4.9 5.2 2.6 4.2 4.5 6.2 5.3 5.0 5.1 8.2 5.1 8.3 4.1 4.0 8.0 6.1 10.4 5.7 3.9 5.4 11.5 6.4 10.4 4.2 3.2 26.4 8.0 4.3 4.8 1.1 6.2 4.8 13.9 5.1 12.3 8.1 22.6 7.8 3.5 2.5 7.5 9.1 8.2 6.7 11.7 5.2 4.4 7.1 8.7 5.7 9.4 7.7 24.3 7.2 25.7 8.5 7.2 12.9 8.1 16.1 11.4 14.7 13.2 7.9 21.8 14.4 10.8 5.6 34.7 19.3 5.5 9.4 9.9 15.0 6.5 7.2 37.3 35.1 17.5 11.2 9.7 33.1 16.8 8.0 18.5 10.3 27.0 17.5 22.2 12.8 9.3 12.0 7.2 13.7 8.4 37.0 8.0 18.9 8.2 10.4 11.6 11.7 8.0 9.1 15.5 15.8 51.8 3.6 17.2 9.8 1.2 2.6 2.4 1.5 1.4 1.1 1.0 1.2 1.5 1.5 1.2 1.2 1.5 1.5 0.5 1.8 1.1 0.9 0.9 8.1 9.7 5.1 10.8 5.3 5.0 4.1 4.0 5.4 1.1 5.1 7.5 1.4 3.2 4.6 4.6 5.3 0.5 2.0 0.4 0.6 8.6 3.5 3.9 7.7 2.8 2.7 1.8 62.6 2.1 4.1 1.0 0.0 1.2 9.2 2.2 2.3 2.3 7.2 5.0 12.5 3.1 1.4 2.1 3.1 2.7 1.3 3.7 3.6 6.9 5.4 11.8 10.3 2.9 2.0 10.1 1.1 7.6 1.5 6.2 0.0 8.4 6.8 3.4 3.1 9.5 9.9 2.6 1.0 1.9 5.8 3.0 1.6 3.7 1.6 6.4 0.0 5.8 1.8 32.0 2.2 1.6 0.6 1.4 3.9 3.8 2.8 0.6 NEURL2 "C20orf163, dJ337O18.6, FLJ30259, Ozz, Ozz-E3" ENSG00000124257 "Neuralized E3 ubiquitin protein ligase 2" Q9BR09 20 45888625-45891208 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 26.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 13.1;Proximal tubular cells: 17.3;Sertoli cells: 13.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 8.2;Hep G2: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043402, HPA059842" Approved Approved Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA043402: AB_2678464, HPA059842: AB_2684139" "unprognostic (6.26e-2)" "unprognostic (1.77e-2)" "unprognostic (1.92e-1)" "unprognostic (1.48e-2)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (3.23e-3)" "unprognostic (1.07e-1)" "unprognostic (8.04e-2)" "unprognostic (2.90e-1)" "unprognostic (1.73e-3)" "unprognostic (5.58e-2)" "unprognostic (1.99e-2)" "unprognostic (6.94e-2)" "unprognostic (1.97e-1)" "unprognostic (8.12e-2)" "unprognostic (1.58e-1)" 14.1 9.1 1.8 2.6 3.0 1.3 6.9 4.0 3.1 5.2 4.5 7.3 4.3 6.2 3.0 2.6 7.4 2.9 8.9 2.0 2.1 26.7 8.2 3.9 1.5 2.4 2.3 9.4 4.4 3.8 4.1 3.1 2.3 4.4 2.2 4.2 5.5 2.7 18.1 4.7 6.5 4.0 2.0 5.9 5.0 2.5 2.1 7.6 5.8 8.9 1.3 7.9 4.3 3.2 0.9 0.7 1.9 1.6 3.1 1.3 1.6 1.2 1.4 1.3 0.6 8.2 5.2 1.0 1.7 0.9 2.3 2.7 1.6 0.0 0.8 0.6 1.4 0.6 6.4 8.5 3.9 0.6 1.4 2.9 1.1 1.3 0.5 2.0 1.0 1.6 0.8 2.1 0.7 3.2 1.0 0.6 0.9 0.5 2.9 1.7 1.4 0.5 0.8 0.7 4.2 3.0 1.7 4.1 5.2 0.4 3.1 1.7 2.0 1.5 1.3 1.2 1.2 6.0 1.3 0.2 1.7 0.8 1.4 0.0 0.6 1.8 0.4 0.3 0.2 2.8 0.7 0.6 0.2 1.0 1.5 1.3 0.2 1.0 0.2 0.3 0.5 0.3 1.8 3.0 4.0 3.1 2.0 2.1 2.4 2.3 2.3 2.0 2.1 3.2 1.7 0.0 0.0 2.0 2.3 0.1 2.1 1.0 2.8 3.5 2.2 3.4 5.7 0.0 0.4 0.0 4.2 0.7 0.5 5.0 7.9 3.2 2.8 0.8 2.3 2.7 3.0 1.3 1.4 2.0 0.9 3.3 3.1 0.9 0.0 7.8 5.7 5.7 13.1 0.0 2.3 2.3 0.0 5.1 0.3 8.6 5.3 1.2 0.0 1.0 1.5 2.5 2.1 2.0 1.4 2.9 0.7 3.8 2.2 2.3 6.7 17.3 0.5 3.4 13.1 3.2 6.1 0.0 0.3 1.8 1.1 0.5 0.7 11.0 2.1 1.7 NFE2L3 Nrf3 ENSG00000050344 "Nuclear factor, erythroid 2 like 3" Q9Y4A8 7 26152198-26187137 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.7;placenta: 34.4" "Group enriched" "Detected in many" 14 "Cytotrophoblasts: 305.9;Syncytiotrophoblasts: 698.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 133.5;NTERA-2: 113.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA055889 Enhanced Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Vesicles" "HPA055889: AB_2682958" "unprognostic (4.99e-2)" "unprognostic (3.11e-1)" "unprognostic (4.36e-3)" "unprognostic (5.37e-2)" "unprognostic (8.41e-2)" "unprognostic (4.00e-3)" "unprognostic (7.29e-3)" "unprognostic (1.87e-1)" "unprognostic (2.12e-1)" "unprognostic (9.88e-2)" "prognostic unfavorable (6.62e-5)" "unprognostic (2.32e-1)" "prognostic unfavorable (7.58e-12)" "prognostic favorable (2.14e-4)" "unprognostic (2.40e-1)" "unprognostic (8.25e-2)" "unprognostic (4.13e-3)" 3.6 3.1 4.2 10.6 7.3 2.5 2.2 19.5 19.7 1.5 2.3 6.3 8.0 2.2 0.2 2.4 1.6 4.3 1.4 6.3 4.8 2.5 1.6 4.8 8.0 7.0 4.6 1.1 4.8 0.4 1.3 34.4 7.2 1.4 4.8 5.1 3.2 0.6 2.7 7.3 5.7 1.0 5.1 7.6 7.3 1.4 6.3 5.9 1.0 0.2 7.0 4.8 1.5 10.8 40.9 3.5 1.6 4.0 0.0 0.0 133.5 7.9 15.2 15.0 27.3 26.2 68.8 3.0 51.2 0.8 57.5 8.6 6.0 13.4 33.7 27.9 8.5 5.7 7.0 19.8 10.5 5.0 52.3 1.3 1.6 6.2 2.3 22.4 35.0 11.3 8.6 69.9 3.0 5.5 3.5 8.8 113.9 11.1 13.9 5.0 0.4 20.5 20.5 40.5 12.3 14.7 0.2 3.2 1.2 37.5 1.9 3.0 76.0 1.4 2.3 0.6 32.6 42.0 72.2 3.4 0.2 17.5 53.1 0.0 0.2 0.0 0.1 0.2 0.3 0.2 0.4 0.2 0.6 0.2 0.2 0.1 0.1 0.2 0.0 0.2 0.6 0.1 4.2 7.3 19.5 19.7 6.3 4.8 7.0 4.6 7.2 5.1 6.3 10.8 14.6 6.4 2.8 3.9 4.6 1.8 4.2 12.7 5.2 1.4 3.1 2.3 1.9 14.3 6.9 11.0 0.0 305.9 1.6 6.1 0.0 13.0 1.0 6.1 1.8 7.6 1.2 12.0 3.8 5.3 33.9 2.8 14.3 6.4 27.9 35.2 2.2 0.3 24.3 0.0 4.4 6.6 12.2 15.6 17.2 0.3 0.0 16.7 1.8 2.8 11.1 1.1 4.1 1.5 11.6 15.6 4.1 0.0 18.2 10.4 2.7 0.5 8.9 1.9 0.0 2.9 2.7 0.6 7.1 5.5 1.6 698.6 9.0 4.8 9.8 6.7 NHLRC1 "bA204B7.2, EPM2B" ENSG00000187566 "NHL repeat containing E3 ubiquitin protein ligase 1" Q6VVB1 6 18120440-18122677 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" Transferase "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythroid cells: 5.0;Exocrine glandular cells: 3.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 6.8;K-562: 6.1;SCLC-21H: 6.1" "Low region specificity" "Detected in all" HPA066030 Uncertain Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 15: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA066030: " "unprognostic (1.61e-1)" "unprognostic (1.39e-1)" "unprognostic (7.95e-2)" "prognostic unfavorable (9.01e-4)" "unprognostic (6.95e-3)" "unprognostic (2.45e-1)" "unprognostic (1.09e-1)" "unprognostic (3.69e-1)" "unprognostic (2.39e-1)" "unprognostic (7.17e-2)" "unprognostic (5.07e-3)" "unprognostic (1.28e-1)" "unprognostic (2.32e-2)" "unprognostic (3.19e-1)" "unprognostic (2.33e-1)" "unprognostic (2.77e-2)" "prognostic favorable (5.30e-4)" 1.2 1.4 2.0 0.8 2.3 1.1 2.0 1.5 2.6 0.8 0.8 1.5 1.4 0.8 2.6 1.1 1.4 0.6 1.8 2.4 1.9 0.8 4.1 1.2 0.6 2.5 1.8 1.4 1.8 1.2 1.2 0.5 2.7 1.2 1.3 2.0 2.3 1.0 2.6 3.8 1.9 0.8 1.6 1.1 1.3 0.7 2.0 1.0 1.6 1.5 0.8 0.9 0.8 3.6 2.6 1.5 0.6 0.0 1.3 1.2 0.0 2.6 0.8 0.9 0.5 0.1 2.1 0.0 6.8 1.9 0.2 3.0 0.0 1.7 0.7 0.1 0.9 0.4 1.0 0.1 2.0 0.0 1.7 2.1 2.5 1.0 0.9 0.6 2.1 0.0 6.1 0.1 2.1 2.8 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.1 1.4 2.8 6.1 0.1 5.3 4.3 1.6 0.6 3.1 1.7 0.4 0.2 1.3 1.8 0.1 0.1 0.0 0.1 0.1 0.0 2.6 0.5 4.4 0.4 0.6 4.9 0.8 2.3 1.1 0.5 4.7 1.3 1.5 1.0 0.3 1.6 2.3 0.6 1.3 1.8 2.0 2.3 1.5 2.6 2.4 1.9 2.5 1.8 2.7 1.6 2.0 3.6 0.8 0.0 2.2 0.3 0.2 1.9 1.4 1.4 1.8 0.4 1.5 2.0 0.9 1.5 2.3 0.0 0.0 0.4 0.0 0.2 0.0 2.9 0.0 0.6 1.3 0.3 3.5 5.0 1.0 3.7 0.0 0.8 1.5 0.5 1.3 0.8 0.4 1.1 1.2 0.0 0.7 0.3 0.0 0.8 0.6 0.0 0.6 1.5 1.8 1.0 0.5 1.1 0.0 1.5 1.2 2.0 0.3 0.0 0.0 0.2 0.6 1.2 0.8 1.0 0.0 0.3 0.8 0.2 0.2 1.3 1.8 0.4 0.1 1.1 0.5 0.5 NIF3L1 "ALS2CR1, CALS-7, MDS015" ENSG00000196290 "NGG1 interacting factor 3 like 1" Q9GZT8 2 200889327-200903938 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 90.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036335, HPA036336, HPA061466" Supported Approved Vesicles NA NA 9800000 "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA036335: AB_10696654, HPA036336: AB_2675068, HPA061466: AB_2684532" "unprognostic (6.61e-2)" "unprognostic (1.16e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (9.52e-5)" "unprognostic (2.48e-2)" "unprognostic (5.92e-2)" "prognostic unfavorable (2.51e-6)" "unprognostic (1.94e-1)" "unprognostic (8.53e-3)" "unprognostic (6.75e-3)" "unprognostic (3.12e-2)" "unprognostic (2.65e-2)" "unprognostic (6.09e-2)" "unprognostic (1.16e-1)" "unprognostic (2.83e-1)" "unprognostic (6.04e-3)" "unprognostic (8.61e-2)" 13.2 19.2 14.1 15.2 15.8 11.0 24.3 15.7 23.8 17.7 13.7 21.8 16.5 15.9 26.3 16.7 22.5 13.2 21.5 14.9 14.8 24.3 22.9 15.6 26.5 15.3 13.8 21.4 15.5 27.0 9.7 19.1 16.2 17.2 28.0 32.7 19.8 19.8 23.5 21.6 15.7 19.1 15.6 18.1 20.1 18.5 14.1 26.5 19.4 30.6 32.4 17.1 12.7 17.5 39.5 42.1 66.9 41.3 29.8 37.1 45.9 42.6 45.4 88.6 71.3 66.1 44.7 31.8 40.2 36.5 64.1 42.7 96.8 56.0 94.6 42.4 90.8 47.4 73.6 70.9 27.0 56.8 31.3 31.7 52.3 58.6 55.8 39.9 29.9 65.6 70.2 31.4 52.7 51.4 69.9 71.1 79.1 44.7 73.5 41.1 37.1 61.6 46.8 40.6 42.3 49.5 36.6 36.8 51.9 94.4 36.5 50.5 15.6 42.2 39.8 38.3 39.0 28.4 58.3 68.4 41.4 45.6 41.6 70.1 23.0 30.7 27.8 34.9 29.1 31.4 31.8 35.3 28.8 23.7 35.4 29.1 7.8 33.6 31.1 29.8 32.0 24.2 14.1 15.8 15.7 23.8 14.9 14.8 15.3 13.8 16.2 15.6 14.1 17.5 6.0 0.0 7.0 2.6 11.7 3.7 7.7 43.1 12.5 90.5 6.9 9.3 13.9 10.0 26.5 5.5 14.6 34.3 8.0 7.5 15.6 20.3 16.2 10.2 9.3 7.0 1.8 23.2 6.2 18.2 35.6 9.8 9.7 7.8 9.5 12.7 6.8 9.3 17.2 18.5 5.7 10.5 26.4 7.3 2.2 6.5 16.1 9.5 5.4 5.6 17.2 18.8 8.2 2.5 5.7 13.2 9.2 19.2 23.9 6.3 10.1 21.3 24.9 27.4 6.6 7.2 14.5 30.9 24.4 12.9 8.2 22.6 10.0 11.1 11.4 6.2 NIPBL "DKFZp434L1319, FLJ11203, FLJ12597, FLJ13354, FLJ13648, IDN3, Scc2" ENSG00000164190 "NIPBL cohesin loading factor" Q6KC79 5 36876769-37066413 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Activator, Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 303.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040834, HPA058239" Approved Supported Nucleoplasm,Vesicles,Cytosol No No "Cluster 18: Basophils - Vesicular transport" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Vesicles, Cytosol" "HPA040834: AB_10796562, HPA058239: AB_2683650" "unprognostic (4.92e-2)" "unprognostic (9.77e-2)" "unprognostic (5.28e-2)" "unprognostic (8.10e-2)" "unprognostic (9.38e-2)" "unprognostic (6.02e-2)" "unprognostic (7.34e-2)" "unprognostic (3.04e-2)" "unprognostic (3.85e-2)" "unprognostic (1.33e-1)" "unprognostic (1.12e-1)" "unprognostic (6.39e-2)" "unprognostic (6.59e-2)" "unprognostic (2.33e-1)" "unprognostic (3.41e-1)" "unprognostic (1.04e-1)" "unprognostic (3.40e-2)" 11.5 9.4 5.6 14.7 8.6 25.1 13.5 12.0 7.3 12.9 7.8 12.2 10.0 13.4 6.6 11.4 10.5 11.1 7.7 5.3 5.9 11.6 12.7 11.9 16.5 7.3 6.6 17.6 13.1 19.6 5.0 13.9 8.2 11.1 12.2 22.4 11.2 10.7 9.5 14.2 13.2 12.4 6.3 15.3 13.4 14.2 6.9 29.8 17.2 14.3 16.7 12.6 7.5 11.1 22.5 13.1 33.3 15.6 20.7 22.3 24.4 17.6 19.3 18.9 15.7 18.2 22.6 33.5 11.3 21.6 22.2 19.2 28.9 15.9 27.0 27.9 14.7 40.9 57.4 13.3 14.0 48.4 26.4 16.5 19.3 21.3 28.1 18.1 24.0 20.8 39.3 24.5 17.9 10.8 33.8 18.1 16.0 12.9 11.3 28.2 51.9 13.0 13.1 31.4 24.5 17.2 84.6 22.5 18.0 26.2 23.0 27.3 26.3 24.9 27.1 21.0 13.3 17.7 25.5 39.1 13.6 32.4 19.1 10.9 2.9 4.3 3.2 2.2 3.0 2.8 2.7 2.9 2.3 3.1 2.9 3.3 7.7 2.8 3.3 3.4 2.1 1.6 5.6 8.6 12.0 7.3 5.3 5.9 7.3 6.6 8.2 6.3 6.9 11.1 80.6 131.4 108.6 169.8 84.8 48.4 66.2 34.2 58.1 62.6 43.6 49.4 87.0 38.6 63.3 33.1 77.2 44.1 107.1 45.9 5.9 55.5 13.4 72.9 75.7 74.1 41.5 85.4 179.2 46.7 34.1 64.3 61.2 91.7 84.0 77.7 44.6 28.2 37.1 40.4 165.5 46.3 38.7 51.8 46.6 15.1 66.5 86.7 24.9 236.1 103.3 49.2 97.9 229.2 303.7 55.0 48.6 56.4 84.5 66.4 45.2 12.2 65.2 72.8 52.6 102.9 80.1 185.8 133.6 58.2 47.0 75.9 92.0 73.8 42.9 88.0 NISCH "I-1, IRAS, KIAA0975" ENSG00000010322 Nischarin Q9Y2I1 3 52455118-52493068 "FDA approved drug targets, Predicted intracellular proteins" Apoptosis Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enteroendocrine cells: 169.3;Peritubular cells: 246.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023189 Approved Approved "Nucleoplasm,Vesicles,Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Nucleoplasm, Cytosol" "Vesicles, Microtubules, Cytokinetic bridge" "HPA023189: AB_1854495" "unprognostic (6.66e-2)" "unprognostic (1.58e-1)" "unprognostic (1.59e-3)" "unprognostic (4.11e-3)" "unprognostic (1.64e-1)" "unprognostic (8.08e-3)" "unprognostic (1.60e-2)" "unprognostic (6.56e-3)" "unprognostic (4.96e-2)" "unprognostic (8.33e-3)" "prognostic favorable (1.91e-4)" "unprognostic (1.40e-2)" "unprognostic (5.10e-2)" "unprognostic (1.19e-1)" "unprognostic (2.94e-2)" "unprognostic (1.47e-1)" "unprognostic (7.05e-3)" 55.2 69.8 46.5 28.7 55.5 38.7 60.5 78.2 56.6 105.8 22.2 68.5 24.3 76.2 34.0 51.3 72.0 29.9 48.5 56.3 38.7 54.6 45.6 56.2 32.5 20.9 32.6 93.0 54.1 32.5 181.8 39.1 32.9 107.5 20.6 19.0 53.6 51.6 36.3 80.7 55.3 33.0 9.1 54.1 52.7 84.5 35.2 30.1 60.8 16.3 23.3 78.1 71.6 35.2 15.6 16.0 48.8 40.1 35.7 39.2 40.0 32.8 21.5 25.7 26.0 24.2 22.8 21.7 9.0 45.6 21.0 20.4 26.1 35.7 15.1 22.3 28.2 39.2 65.2 23.9 32.4 23.2 33.6 61.9 28.2 27.7 23.5 54.0 42.0 42.4 21.1 23.4 24.3 22.2 41.8 51.2 30.1 19.8 27.1 24.5 13.4 25.4 29.2 30.6 20.6 35.9 35.6 9.3 23.1 42.3 28.9 38.5 46.3 36.0 34.1 36.9 24.1 38.7 23.8 27.3 24.7 37.3 22.4 5.2 4.5 3.5 3.0 4.0 3.1 2.5 2.6 4.0 2.3 2.8 3.1 3.3 1.5 3.2 0.6 3.4 3.0 3.6 46.5 55.5 78.2 56.6 56.3 38.7 20.9 32.6 32.9 9.1 35.2 35.2 26.1 25.6 32.3 34.0 14.9 27.5 14.6 23.3 40.5 40.9 29.2 37.1 20.4 8.6 19.1 14.7 8.4 32.4 24.2 20.5 9.8 12.1 10.3 14.5 26.7 22.1 169.3 4.6 64.9 9.4 14.0 23.4 23.4 18.9 25.3 40.2 46.1 15.3 30.5 28.6 44.0 19.1 22.4 50.5 14.5 25.9 88.3 24.3 19.6 15.0 13.0 12.1 17.5 21.1 26.1 10.0 14.2 246.0 12.4 12.6 16.5 15.6 15.2 22.4 26.3 17.2 24.8 31.2 18.0 16.7 22.3 24.2 18.4 47.6 15.7 11.7 NKG7 "GIG1, GMP-17" ENSG00000105374 "Natural killer cell granule protein 7" Q16617 19 51371606-51372701 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 602.6;lymphoid tissue: 154.6" "Group enriched" "Detected in many" 4 "dendritic cells: 3163.4;NK-cells: 7721.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "gdT-cell: 6827.0;MAIT T-cell: 2871.2;memory CD8 T-cell: 4295.0;naive CD8 T-cell: 3114.2;NK-cell: 4796.8" "Group enriched" "Detected in all" 44 "NK-cells: 4796.8;T-cells: 6827.0" "Group enriched" "Detected in some" 5 "NB-4: 180.8;THP-1: 54.5;U-937: 46.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071454 Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA071454: AB_2686399" "unprognostic (1.56e-2)" "unprognostic (1.05e-2)" "unprognostic (6.54e-2)" "prognostic favorable (7.42e-6)" "unprognostic (1.27e-2)" "unprognostic (3.25e-3)" "unprognostic (2.96e-3)" "unprognostic (2.14e-1)" "unprognostic (3.22e-3)" "unprognostic (3.89e-3)" "unprognostic (3.39e-1)" "unprognostic (9.93e-2)" "prognostic unfavorable (3.32e-6)" "unprognostic (7.62e-3)" "unprognostic (2.61e-1)" "unprognostic (1.30e-2)" "unprognostic (6.44e-3)" 12.5 7.9 3.7 23.2 3.6 602.6 7.7 3.6 6.3 5.9 4.2 9.5 11.0 12.5 6.1 7.2 7.9 21.4 6.7 3.5 3.6 6.5 23.5 49.2 136.4 4.9 3.9 4.2 2.2 2.2 3.2 7.9 4.2 4.9 7.3 0.4 9.6 4.5 6.5 2.7 14.6 7.7 4.1 154.6 10.6 3.3 4.3 9.4 6.6 3.3 21.9 16.7 4.4 4.2 0.1 0.3 0.2 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.9 7.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 7.6 0.6 2.0 0.8 0.2 0.0 20.1 3.6 0.0 0.0 0.3 0.0 0.2 0.0 2.5 0.5 0.8 0.0 0.0 2.4 180.8 0.0 0.2 0.3 4.4 9.4 0.4 0.0 0.0 0.1 0.2 0.4 0.1 0.1 0.3 0.0 54.5 0.4 0.1 0.2 0.6 0.1 2.6 0.9 0.9 0.1 46.6 0.0 76.9 34.1 15.2 6827.0 131.7 2871.2 37.9 811.1 4295.0 87.1 15.4 261.0 3114.2 111.7 4796.8 104.8 67.1 17.5 4929.2 3.7 3.6 3.6 6.3 3.5 3.6 4.9 3.9 4.2 4.1 4.3 4.2 17.2 3.2 8.0 0.0 24.5 5.0 0.1 0.0 0.0 0.0 5.7 3.7 0.7 28.6 1.3 5.5 0.0 1.0 3163.4 1.9 3.9 1.0 0.2 2.7 3.6 7.1 0.0 186.5 0.0 0.0 0.8 5.2 17.3 4.2 24.1 0.2 55.3 9.9 15.0 0.0 0.0 0.5 0.0 132.9 10.2 0.3 0.0 55.5 17.8 1.0 49.4 0.0 7721.0 0.0 0.2 0.0 1.2 0.0 120.4 0.0 0.6 9.2 0.7 0.0 0.0 6.4 4.7 0.0 0.5 1.1 6.5 1.1 1321.5 0.0 1.1 0.1 NKX2-1 "BCH, NKX2A, TITF1, TTF-1, TTF1" ENSG00000136352 "NK2 homeobox 1" P43699 14 36516392-36521149 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "lung: 53.1;thyroid gland: 172.4" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 137.8;Alveolar cells type 2: 124.8" "Group enriched" "Detected in some" 39 "lung cancer: 30.9;thyroid cancer: 103.2" "Region enhanced" "Detected in many" "thalamus: 17.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "SCLC-21H: 78.7" "Group enriched" "Detected in some" 5 "basal ganglia: 3.2;hypothalamus: 10.2" "Group enriched" "Detected in some" 13 "basal ganglia: 4.3;hypothalamus: 10.4" "CAB000078, CAB053633, HPA074316" Enhanced Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 11: Alveolar cells - Smell perception" "Golgi apparatus, Vesicles" "CAB000078: , CAB053633: AB_442138, HPA074316: " "unprognostic (3.79e-1)" "unprognostic (4.25e-3)" "unprognostic (1.12e-1)" "unprognostic (1.79e-2)" "unprognostic (1.26e-2)" "unprognostic (2.23e-1)" "unprognostic (1.18e-1)" "unprognostic (1.29e-1)" "unprognostic (1.83e-2)" "unprognostic (4.18e-1)" 0.0 0.1 1.1 0.0 2.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 10.1 0.0 0.0 53.1 0.0 0.0 0.3 0.1 0.1 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 17.8 0.0 172.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 78.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.0 0.0 4.0 0.1 10.1 0.0 0.3 0.0 0.0 17.8 0.1 0.0 137.8 124.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.0 0.0 0.1 0.7 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 NLRC3 "CLR16.2, FLJ00348, NOD3" ENSG00000167984 "NLR family CARD domain containing 3" Q7RTR2 16 3539033-3577403 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.5;lymphoid tissue: 13.6" "Cell type enhanced" "Detected in many" "B-cells: 10.3;dendritic cells: 18.8;NK-cells: 37.0;T-cells: 23.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 8.8;HEL: 8.7;HL-60: 18.6;HMC-1: 9.0;JURKAT: 9.2;NB-4: 19.7;U-698: 28.9;U-937: 13.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA048062 Supported "Vesicles,Centriolar satellite,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Vesicles, Centriolar satellite" "HPA048062: AB_2680242" "unprognostic (4.93e-3)" "unprognostic (3.84e-4)" "unprognostic (7.61e-4)" "unprognostic (4.94e-7)" "unprognostic (9.56e-2)" "unprognostic (3.76e-5)" "unprognostic (1.86e-3)" "unprognostic (6.70e-3)" "unprognostic (2.66e-2)" "unprognostic (7.02e-2)" "unprognostic (3.40e-2)" "unprognostic (5.20e-2)" "unprognostic (1.40e-2)" "unprognostic (5.13e-2)" "unprognostic (7.15e-3)" "unprognostic (4.54e-2)" "unprognostic (2.08e-2)" 1.0 0.8 0.3 7.8 0.4 4.1 0.7 0.8 0.7 0.9 1.0 1.5 1.7 0.9 0.4 0.8 1.2 1.4 1.5 0.3 0.0 1.3 1.1 2.4 13.6 0.3 0.3 0.7 0.5 0.2 0.9 0.9 0.1 1.1 1.2 1.1 1.1 0.3 1.1 0.5 6.5 0.5 0.0 11.8 2.1 0.9 0.3 11.3 1.5 0.9 11.1 1.5 0.8 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 8.8 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.2 8.7 0.1 0.0 0.0 18.6 9.0 0.0 0.0 0.0 0.0 0.5 0.2 9.2 0.2 0.0 0.0 0.4 7.7 19.7 0.0 0.0 0.1 5.1 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.3 0.1 0.1 4.9 0.5 0.3 0.1 0.2 0.1 0.4 0.2 28.9 0.2 13.6 0.1 2.9 0.0 0.0 2.3 0.0 2.1 0.8 1.7 2.2 0.0 0.6 1.4 1.5 0.0 2.6 0.0 0.0 2.0 2.1 0.3 0.4 0.8 0.7 0.3 0.0 0.3 0.3 0.1 0.0 0.3 0.1 1.7 3.2 0.0 1.0 10.3 0.0 0.3 0.0 0.0 1.6 0.4 0.3 4.6 1.5 0.6 1.8 4.2 0.0 18.8 0.0 0.0 0.0 4.0 1.3 0.8 2.3 0.0 6.5 3.8 0.0 0.0 0.5 1.5 0.7 2.5 0.2 3.9 0.1 0.1 0.0 3.7 0.0 0.0 1.0 0.0 1.3 0.0 1.1 0.0 1.9 1.3 0.3 37.0 1.0 0.6 0.0 0.0 0.0 6.2 0.1 0.0 0.1 0.7 5.1 0.0 0.9 0.7 0.5 0.3 0.0 0.0 0.0 23.8 0.1 0.0 0.3 NLRC4 "CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, ipaf" ENSG00000091106 "NLR family CARD domain containing 4" Q9NPP4 2 32224453-32265732 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.3;lung: 6.2;lymphoid tissue: 11.4" "Cell type enhanced" "Detected in some" "Hofbauer cells: 11.9;Kupffer cells: 21.0;Macrophages: 14.5;Microglial cells: 10.3;monocytes: 18.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "classical monocyte: 49.3;intermediate monocyte: 56.9;myeloid DC: 32.2;neutrophil: 24.6;non-classical monocyte: 44.2" "Group enriched" "Detected in many" 32 "dendritic cells: 32.2;granulocytes: 24.6;monocytes: 56.9" "Cell line enhanced" "Detected in some" "HL-60: 3.1" "Not detected" "Not detected" "HPA006592, HPA075894" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Cytosol" "HPA006592: AB_2667620, HPA075894: " "unprognostic (7.59e-2)" "unprognostic (1.08e-1)" "unprognostic (6.25e-2)" "unprognostic (1.97e-1)" "unprognostic (8.88e-2)" "unprognostic (2.45e-2)" "unprognostic (1.17e-2)" "unprognostic (2.09e-2)" "unprognostic (1.48e-1)" "unprognostic (2.26e-1)" "unprognostic (6.33e-2)" "unprognostic (6.33e-2)" "unprognostic (6.03e-6)" "unprognostic (7.42e-2)" "unprognostic (2.06e-3)" "unprognostic (2.02e-2)" "unprognostic (1.63e-1)" 3.4 1.4 0.4 8.7 0.5 8.3 0.7 0.4 0.8 0.6 0.6 0.9 0.9 0.4 0.0 0.6 0.8 1.4 1.2 0.4 0.4 0.5 1.6 6.2 2.3 0.6 0.5 0.3 0.8 0.1 0.6 2.1 0.6 0.4 0.8 0.6 0.5 0.2 1.0 0.3 1.3 2.3 0.5 11.4 0.6 0.4 0.9 0.7 0.4 0.3 1.2 2.0 0.3 0.8 0.1 0.2 0.3 0.7 0.1 0.0 0.4 0.3 0.0 0.0 0.0 0.3 0.3 0.3 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.7 0.3 0.5 0.1 0.4 0.0 3.1 0.5 0.0 0.3 0.0 1.4 0.4 0.0 0.1 0.3 0.2 0.0 0.0 0.2 1.4 0.1 0.2 0.2 0.1 0.4 0.5 0.0 0.3 0.3 0.7 0.2 0.2 1.2 0.5 0.1 1.4 0.1 0.3 0.3 0.2 0.4 0.3 0.8 1.2 0.4 1.3 0.4 0.5 49.3 5.8 0.1 56.9 0.4 0.6 0.0 0.0 32.2 1.1 0.0 0.1 24.6 0.3 44.2 0.4 0.2 18.6 0.4 0.5 0.4 0.8 0.4 0.4 0.6 0.5 0.6 0.5 0.9 0.8 0.2 0.0 1.8 1.0 0.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 2.7 4.0 0.0 0.1 0.1 0.0 0.0 1.3 0.0 1.1 0.0 11.9 0.0 3.3 0.0 0.0 21.0 1.0 0.0 0.0 14.5 0.0 10.3 18.4 0.0 1.0 1.0 1.3 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.2 0.0 0.3 0.1 0.0 0.2 0.0 0.1 0.3 0.2 0.1 0.0 0.0 NLRP2 "CLR19.9, FLJ20510, NALP2, NBS1, PAN1, PYPAF2" ENSG00000022556 "NLR family pyrin domain containing 2" Q9NX02 19 54953130-55001142 "Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 45.2;Extravillous trophoblasts: 216.1;Syncytiotrophoblasts: 97.3" "Cancer enriched" "Detected in many" 7 "testis cancer: 78.1" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 42.2;BEWO: 177.9;OE19: 79.7;SuSa: 80.3;T-47d: 46.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA021183 Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus, Vesicles, Cytosol" "HPA021183: AB_2670615" "unprognostic (1.66e-2)" "unprognostic (9.28e-2)" "unprognostic (6.60e-2)" "unprognostic (6.50e-3)" "unprognostic (1.09e-2)" "unprognostic (4.57e-3)" "unprognostic (4.27e-1)" "unprognostic (1.79e-2)" "unprognostic (2.39e-1)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (3.63e-1)" "unprognostic (2.34e-2)" "unprognostic (2.55e-1)" "unprognostic (2.30e-1)" "unprognostic (8.86e-2)" "unprognostic (7.57e-2)" 0.4 0.3 0.9 2.7 0.6 1.0 1.0 0.0 0.8 2.6 0.1 1.7 1.8 1.1 1.8 7.9 1.9 0.9 0.4 0.7 0.1 1.9 0.4 1.6 2.1 0.1 0.2 0.3 1.6 0.4 1.2 7.1 0.1 1.5 1.9 3.1 2.4 1.1 0.6 3.0 1.7 0.8 0.0 2.1 2.5 7.2 0.3 3.4 4.4 0.0 1.9 7.1 4.3 0.2 20.4 42.2 15.8 0.4 0.2 0.1 177.9 0.1 0.0 0.6 0.2 35.9 0.7 14.7 0.1 0.1 0.1 8.1 0.0 24.4 0.3 1.7 0.2 9.8 0.5 0.1 0.4 0.1 0.4 0.2 0.3 0.0 0.1 0.1 0.9 0.0 32.7 0.2 0.0 0.3 0.1 1.3 5.0 79.7 0.0 8.8 0.0 24.0 26.4 0.7 5.3 0.7 0.0 8.1 0.0 80.3 46.7 0.2 0.0 0.3 0.7 0.4 0.3 5.2 16.6 0.7 0.4 1.0 0.0 0.1 0.2 0.0 1.8 0.3 1.3 0.6 0.4 0.7 0.2 0.6 0.3 0.8 0.2 3.0 0.1 1.0 1.3 0.4 0.9 0.6 0.0 0.8 0.7 0.1 0.1 0.2 0.1 0.0 0.3 0.2 0.0 9.6 7.3 0.3 1.5 0.5 1.9 8.1 0.0 2.7 1.9 1.5 0.8 4.3 10.1 1.8 4.2 45.2 3.5 2.9 0.0 5.3 23.1 8.6 1.3 0.7 2.4 0.8 3.0 1.9 216.1 1.1 2.0 13.1 4.5 0.7 0.0 0.0 11.6 0.0 1.9 3.0 6.1 0.3 0.5 7.2 0.9 1.1 0.0 0.0 3.0 0.7 8.2 0.5 0.5 6.7 1.0 0.0 1.5 2.5 0.8 0.4 8.4 2.7 0.0 0.3 0.8 16.8 11.7 0.0 1.3 97.3 2.4 0.3 3.0 4.7 NLRP5 "CLR19.8, MATER, NALP5, PAN11, PYPAF8" ENSG00000171487 "NLR family pyrin domain containing 5" P59047 19 55999726-56061810 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 50 "parathyroid gland: 22.4" "Cell type enhanced" "Detected in some" "Microglial cells: 1.0;Oligodendrocyte precursor cells: 2.0;Oligodendrocytes: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "Karpas-707: 1.3;U-2 OS: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047260, HPA056271" Uncertain Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 9: U-2 OS - Unknown function" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" Vesicles "HPA047260: , HPA056271: AB_2683083" "unprognostic (9.67e-2)" "unprognostic (2.22e-2)" "unprognostic (5.03e-1)" "unprognostic (7.78e-2)" "unprognostic (1.72e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 22.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.1 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 2.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NMB "MGC17211, MGC2277, MGC3936" ENSG00000197696 "Neuromedin B" P08949 15 84655129-84658563 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 68.3;brain: 58.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 319.5;Club cells: 164.2;Ductal cells: 123.9" "Cancer enhanced" "Detected in all" "glioma: 93.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 90.1" "Region enriched" "Detected in all" 16 "olfactory bulb: 168.0" "Group enriched" "Detected in all" 5 "olfactory bulb: 43.3;pons: 14.1" CAB019302 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted to blood" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Vesicles" "Plasma membrane" "CAB019302: " "unprognostic (2.44e-2)" "unprognostic (1.10e-1)" "unprognostic (2.34e-3)" "unprognostic (3.79e-1)" "prognostic favorable (3.43e-4)" "unprognostic (3.81e-1)" "unprognostic (6.45e-2)" "unprognostic (1.45e-2)" "unprognostic (2.17e-1)" "unprognostic (4.36e-1)" "unprognostic (7.24e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.25e-4)" "unprognostic (7.92e-3)" "unprognostic (1.45e-1)" "unprognostic (1.71e-2)" "unprognostic (1.00e-1)" 68.3 24.0 19.9 4.1 17.9 6.0 30.7 18.2 23.5 8.3 16.3 5.3 3.1 7.5 4.9 6.9 8.6 4.8 5.4 21.4 58.9 10.7 3.1 6.2 5.7 29.3 22.7 7.1 8.4 4.5 9.8 1.9 26.2 5.0 2.9 3.0 7.4 2.5 2.5 4.9 4.1 4.7 22.4 4.8 5.5 11.9 21.4 4.5 17.7 3.1 3.0 8.5 6.5 44.7 90.1 35.3 6.1 1.3 17.1 7.7 0.8 4.7 10.5 12.5 16.6 12.9 23.5 3.4 12.9 14.7 0.1 15.0 34.0 7.0 7.4 30.3 36.7 12.4 13.2 59.7 4.4 8.2 13.6 7.6 2.8 18.2 7.2 7.6 17.9 23.3 0.2 1.4 6.9 55.2 8.8 30.0 22.9 18.0 8.9 25.7 0.1 38.7 11.5 7.3 3.1 34.6 8.2 5.1 40.5 6.0 5.9 33.8 4.0 2.4 10.3 10.3 7.9 0.7 9.9 8.2 26.3 52.9 14.1 0.0 1.0 7.8 7.9 0.7 2.9 5.9 5.9 7.7 4.5 11.3 5.8 4.1 1.6 1.8 0.5 13.4 7.6 3.4 19.9 17.9 18.2 23.5 21.4 58.9 29.3 22.7 26.2 22.4 21.4 44.7 39.0 3.2 2.7 5.5 13.6 15.6 29.5 319.5 21.6 1.9 30.7 37.6 3.5 20.0 164.2 31.3 0.0 2.4 25.3 5.3 13.7 123.9 33.7 21.3 7.3 19.6 18.6 7.4 0.6 58.2 14.1 19.7 11.2 15.6 5.7 12.0 7.5 3.7 32.3 5.0 1.2 6.5 18.3 8.8 86.4 29.0 4.4 26.0 33.8 1.9 18.5 6.5 25.7 2.0 1.0 45.2 5.1 3.8 32.5 39.3 0.8 32.0 57.8 4.1 13.1 22.5 28.6 24.0 21.6 29.5 12.8 3.1 19.7 8.2 9.1 60.6 NME6 "IPIA-ALPHA, NM23-H6" ENSG00000172113 "NME/NM23 nucleoside diphosphate kinase 6" O75414 3 48290722-48301685 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Nucleotide metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017909 Approved Approved Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA017909: AB_1854530" "unprognostic (7.31e-3)" "unprognostic (1.87e-1)" "unprognostic (8.19e-3)" "unprognostic (2.09e-2)" "unprognostic (8.52e-2)" "unprognostic (2.20e-1)" "prognostic unfavorable (2.17e-7)" "unprognostic (1.90e-1)" "unprognostic (1.56e-1)" "unprognostic (4.00e-3)" "unprognostic (1.32e-1)" "unprognostic (2.98e-1)" "prognostic favorable (3.18e-5)" "unprognostic (1.98e-2)" "unprognostic (1.57e-2)" "unprognostic (1.23e-1)" "unprognostic (9.50e-2)" 8.7 7.7 6.3 10.4 6.4 8.1 12.1 9.2 6.3 10.2 8.7 11.6 13.2 9.3 8.5 12.1 14.8 8.9 13.5 7.1 6.5 11.1 10.3 10.2 12.2 5.9 6.3 12.4 11.6 12.4 6.0 14.2 5.7 9.5 11.5 7.6 10.9 8.7 17.7 10.0 10.4 12.4 4.9 9.6 11.5 6.2 6.4 9.4 12.2 17.2 13.7 9.6 9.0 6.3 30.0 19.1 24.3 18.3 18.2 23.4 22.1 27.2 18.3 37.5 27.3 30.5 26.5 30.1 14.0 20.5 36.5 10.1 21.9 27.2 24.1 36.1 21.3 17.9 24.1 26.6 25.7 24.3 20.7 19.7 33.8 34.4 42.9 19.3 19.8 21.1 33.9 23.6 14.0 13.9 21.4 11.3 22.3 19.5 23.3 12.7 22.9 25.3 21.2 23.6 7.7 12.7 19.8 21.0 26.1 17.8 23.9 22.5 22.1 8.3 33.0 21.2 39.4 27.0 40.9 26.1 16.3 31.9 18.4 47.3 33.4 76.4 40.9 36.0 36.6 43.5 37.4 35.2 39.9 38.0 28.1 27.2 37.3 40.4 42.1 34.5 33.5 25.1 6.3 6.4 9.2 6.3 7.1 6.5 5.9 6.3 5.7 4.9 6.4 6.3 13.1 28.9 20.7 2.3 16.4 5.0 8.5 18.2 9.6 11.9 14.1 13.6 10.4 15.7 19.4 9.2 14.6 49.5 18.4 8.2 39.2 24.8 2.6 16.1 17.5 12.8 4.2 8.0 2.5 30.1 41.6 12.4 11.7 11.8 10.1 22.8 7.9 7.9 34.4 10.1 3.2 10.8 12.2 9.3 9.7 1.7 11.8 13.7 16.0 1.9 23.4 17.6 18.6 2.5 2.7 31.3 8.3 7.2 10.8 12.8 16.6 16.4 30.6 11.5 13.1 7.7 12.2 9.3 15.0 12.4 4.1 19.7 14.7 15.1 12.8 7.1 NMRK2 "ITGB1BP3, MIBP, NRK2" ENSG00000077009 "Nicotinamide riboside kinase 2" Q9NPI5 19 3933103-3942416 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 116 "heart muscle: 1438.4;skeletal muscle: 634.8;tongue: 722.1" "Cell type enriched" "Detected in some" 36 "Cardiomyocytes: 995.1" "Cancer enhanced" "Detected in some" "renal cancer: 32.8;testis cancer: 13.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BEWO: 29.2;NTERA-2: 24.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049909, HPA054792, HPA072450" Approved Enhanced Nucleoplasm,Vesicles NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" Nucleoplasm Vesicles "HPA049909: , HPA054792: AB_2682601, HPA072450: AB_2686522" "unprognostic (3.61e-1)" "unprognostic (5.92e-2)" "unprognostic (1.18e-2)" "unprognostic (2.54e-1)" "unprognostic (1.03e-1)" "unprognostic (7.61e-2)" "unprognostic (3.30e-2)" "prognostic favorable (1.19e-4)" "unprognostic (1.72e-1)" "unprognostic (3.29e-2)" "unprognostic (5.38e-1)" 0.7 1.7 0.2 0.0 0.2 0.0 0.8 0.2 0.8 0.2 0.2 0.5 0.0 0.4 0.1 5.7 0.6 0.0 1438.4 0.2 0.4 1.9 0.3 2.1 0.0 0.3 0.4 0.5 0.6 0.0 1.7 0.1 0.1 2.6 0.1 0.0 8.0 0.8 634.8 0.7 0.5 0.0 0.2 0.1 0.6 0.5 0.2 0.0 0.6 722.1 0.0 0.4 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 29.2 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 24.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.7 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.8 0.2 0.4 0.3 0.4 0.1 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 995.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.4 0.0 0.0 0.2 0.0 0.6 26.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 24.6 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 NOL12 "MGC3731, Nop25, RRP17" ENSG00000273899 "Nucleolar protein 12" Q9UGY1 22 37681673-37693476 "Predicted intracellular proteins" "RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 105.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA003547 Uncertain Approved "Nucleoplasm,Nucleoli,Mitotic chromosome,Vesicles" Yes No "Cluster 34: Basophils - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoli, Mitotic chromosome" "Nucleoplasm, Vesicles" "HPA003547: AB_10602012" "unprognostic (3.37e-2)" "prognostic favorable (6.80e-5)" "unprognostic (2.65e-1)" "unprognostic (9.62e-2)" "unprognostic (2.13e-1)" "unprognostic (7.89e-2)" "unprognostic (3.23e-3)" "prognostic favorable (9.41e-4)" "unprognostic (9.96e-2)" "unprognostic (4.62e-2)" "unprognostic (2.18e-3)" "unprognostic (4.60e-2)" "prognostic unfavorable (2.56e-6)" "unprognostic (1.34e-2)" "unprognostic (8.40e-2)" "unprognostic (4.65e-2)" "prognostic favorable (3.24e-4)" 17.1 29.2 11.3 15.1 12.7 28.7 17.5 12.1 18.0 20.5 9.6 21.3 14.9 15.5 7.9 35.1 16.2 9.0 18.6 11.8 12.3 22.0 16.2 14.3 20.9 12.3 11.8 18.5 17.5 11.5 16.5 8.1 12.1 19.8 9.5 4.9 20.5 4.4 12.6 22.7 19.5 6.6 11.2 26.5 18.8 10.4 11.8 16.1 23.1 8.2 12.6 17.1 23.3 12.9 38.3 33.5 24.4 29.5 8.1 7.8 32.2 17.1 7.7 7.4 8.4 20.0 15.7 30.2 9.8 6.2 8.1 41.4 11.6 50.0 2.2 34.4 51.9 26.3 28.9 43.6 21.3 59.3 38.2 9.6 12.4 31.2 11.7 10.0 15.3 16.7 19.8 26.9 6.8 32.3 36.4 48.0 29.5 16.6 46.7 48.5 16.7 24.7 18.2 10.1 19.2 40.3 22.1 19.5 30.8 2.7 26.9 31.0 22.9 34.2 32.5 24.8 34.5 24.0 29.9 41.0 33.3 46.2 40.0 57.3 24.4 26.9 15.1 28.4 11.7 14.1 14.8 13.6 17.6 15.8 14.8 12.6 53.1 16.7 33.8 13.6 22.3 11.9 11.3 12.7 12.1 18.0 11.8 12.3 12.3 11.8 12.1 11.2 11.8 12.9 10.9 3.2 15.3 4.9 15.3 39.0 13.7 33.0 25.0 11.0 10.2 7.7 3.5 7.2 20.3 14.7 6.2 19.4 11.0 35.6 3.9 25.7 105.7 5.4 5.0 12.9 12.6 8.8 11.4 29.1 16.2 10.2 15.8 4.7 15.2 9.7 10.8 6.2 13.9 28.6 10.9 24.8 20.3 10.7 21.8 48.3 9.9 12.7 21.4 2.8 17.7 13.8 18.6 5.5 8.2 22.4 39.9 11.3 14.0 8.6 27.4 7.8 15.9 8.3 13.1 10.0 10.6 14.5 25.9 45.4 39.8 19.8 14.3 9.7 24.1 14.5 NOS1AP "CAPON, KIAA0464" ENSG00000198929 "Nitric oxide synthase 1 adaptor protein" O75052 1 162069691-162370475 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 22.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 204.3;Excitatory neurons: 142.3;Horizontal cells: 67.3;Inhibitory neurons: 107.6;Oligodendrocyte precursor cells: 79.9;Oligodendrocytes: 82.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 3.9;HaCaT: 3.1;HEL: 4.6" "Low region specificity" "Detected in all" "CAB018582, HPA030066, HPA055561" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 36: HEL - Hemostasis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "CAB018582: AB_2251417, HPA030066: AB_2673294, HPA055561: AB_2682851" "unprognostic (7.04e-3)" "unprognostic (2.20e-1)" "unprognostic (1.79e-2)" "unprognostic (3.93e-2)" "unprognostic (1.58e-2)" "unprognostic (4.75e-2)" "unprognostic (2.07e-1)" "unprognostic (1.89e-1)" "unprognostic (1.95e-1)" "unprognostic (1.54e-1)" "unprognostic (3.48e-1)" "unprognostic (1.71e-1)" "unprognostic (2.15e-5)" "unprognostic (1.82e-2)" "unprognostic (1.49e-1)" "unprognostic (1.62e-1)" "unprognostic (5.08e-3)" 0.4 2.8 16.3 0.1 20.1 1.8 1.2 8.0 16.2 0.6 0.0 1.3 0.6 0.5 0.2 0.7 0.6 0.6 0.8 22.2 2.4 0.9 3.1 0.4 0.0 3.0 2.1 0.2 0.9 0.5 0.8 0.4 0.4 0.7 1.1 3.6 1.5 1.4 0.2 1.1 0.7 0.4 0.0 0.0 1.4 1.8 5.5 0.1 0.1 0.2 0.2 0.6 0.4 21.5 3.9 0.0 1.8 1.1 0.0 0.0 0.2 0.3 0.4 0.5 0.4 0.9 1.0 0.0 2.2 0.1 0.6 3.1 0.6 0.1 0.1 0.1 1.7 4.6 0.6 1.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.5 1.0 0.6 0.4 0.0 0.1 2.1 0.3 0.0 1.3 0.6 1.5 0.0 0.7 0.1 0.9 1.4 1.4 0.9 0.8 0.1 0.6 0.5 1.1 0.2 0.4 0.0 0.4 0.0 0.6 2.2 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.3 20.1 8.0 16.2 22.2 2.4 3.0 2.1 0.4 0.0 5.5 21.5 4.4 0.0 0.5 5.9 0.4 2.9 6.1 0.7 0.6 11.6 14.1 21.5 2.3 2.8 1.5 22.0 204.3 0.2 0.4 7.9 9.8 1.0 36.8 4.5 3.5 3.6 6.7 2.7 142.3 1.2 0.3 1.3 9.7 7.9 0.0 8.0 3.3 21.2 0.1 67.3 107.6 10.2 0.0 0.8 0.4 12.4 4.4 0.2 0.0 43.1 0.0 13.4 1.0 79.9 82.9 0.7 5.3 7.2 0.1 6.8 3.9 0.6 1.7 3.8 6.6 0.9 1.1 2.0 2.2 2.3 2.0 0.5 0.5 1.9 5.3 7.8 NOSTRIN MGC20702 ENSG00000163072 "Nitric oxide synthase trafficking" Q8IVI9 2 168786539-168865514 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 167.0;Endothelial cells: 129.6;Hepatic stellate cells: 172.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 10.1;HEL: 41.9;K-562: 31.8;OE19: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044384, HPA076885" Approved Approved Vesicles,Cytosol NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol Vesicles "HPA044384: AB_2678922, HPA076885: " "unprognostic (4.74e-2)" "unprognostic (2.42e-1)" "unprognostic (8.73e-2)" "unprognostic (2.27e-1)" "unprognostic (3.15e-3)" "unprognostic (3.02e-6)" "unprognostic (4.89e-3)" "unprognostic (3.15e-1)" "unprognostic (3.14e-4)" "unprognostic (5.47e-3)" "unprognostic (1.19e-1)" "unprognostic (2.51e-1)" "unprognostic (1.63e-1)" "unprognostic (1.75e-1)" "unprognostic (2.33e-1)" "unprognostic (6.47e-2)" "unprognostic (4.98e-2)" 32.6 20.4 6.1 4.6 5.8 0.3 31.4 5.0 7.6 17.5 4.2 15.3 14.0 14.9 4.3 5.1 16.4 14.0 16.1 4.9 5.6 32.6 7.3 30.8 4.6 6.6 6.0 10.6 22.6 3.8 3.8 25.4 6.5 13.3 16.4 0.8 48.9 6.8 5.1 7.3 14.3 12.8 5.5 5.5 23.0 14.4 6.6 1.9 13.5 3.6 3.0 8.1 11.3 5.0 0.0 3.6 1.1 0.0 0.0 0.0 10.1 0.4 0.0 0.0 0.0 6.3 6.5 0.1 4.3 0.0 0.0 0.2 0.0 1.6 0.0 0.0 0.0 41.9 1.8 0.0 0.2 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 31.8 0.0 0.0 0.1 0.1 0.1 0.1 20.5 0.3 0.4 1.9 0.0 3.4 1.6 0.0 0.1 0.2 1.9 0.0 0.2 0.5 0.0 0.0 0.0 0.7 0.2 0.6 0.6 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 5.8 5.0 7.6 4.9 5.6 6.6 6.0 6.5 5.5 6.6 5.0 167.0 9.6 10.3 2.0 1.6 1.0 0.6 0.3 0.6 0.1 20.0 11.0 7.1 15.7 3.3 3.7 0.0 18.9 0.4 57.3 13.7 8.0 26.6 16.3 3.3 129.6 11.4 2.7 0.4 21.8 7.0 6.1 41.3 23.2 0.0 72.4 172.5 1.0 1.6 0.0 0.5 35.9 0.0 6.3 0.9 60.9 8.7 1.2 24.9 55.3 0.7 1.6 0.0 2.0 0.0 17.7 53.4 5.7 0.2 3.3 43.1 59.0 1.5 0.3 72.3 1.3 11.3 13.7 1.8 0.4 0.4 26.3 0.9 71.9 20.7 1.2 NOX3 GP91-3 ENSG00000074771 "NADPH oxidase 3" Q9HBY0 6 155395368-155455839 "Predicted membrane proteins, Transporters" Oxidoreductase "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "MCF7: 4.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA073837 Uncertain Vesicles NA NA "Cluster 40: Non-specific - Basic cellular processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA073837: " "unprognostic (3.42e-1)" 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NOXA1 "FLJ25475, NY-CO-31, SDCCAG31" ENSG00000188747 "NADPH oxidase activator 1" Q86UR1 9 137423350-137434406 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 37.5;Gastric mucus-secreting cells: 54.6;Paneth cells: 34.7;Proximal enterocytes: 39.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CAPAN-2: 12.6;EFO-21: 11.3;MCF7: 19.8;T-47d: 18.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA044781 Uncertain Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA044781: AB_10960532" "unprognostic (2.15e-1)" "unprognostic (2.86e-1)" "unprognostic (1.55e-3)" "unprognostic (1.42e-3)" "unprognostic (4.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.79e-1)" "unprognostic (3.99e-3)" "unprognostic (2.72e-1)" "unprognostic (1.69e-1)" "unprognostic (5.45e-3)" "unprognostic (1.97e-3)" "prognostic favorable (2.65e-4)" "unprognostic (4.97e-3)" "unprognostic (2.67e-1)" "unprognostic (1.74e-1)" "unprognostic (3.10e-2)" 3.7 6.6 11.4 3.5 11.9 3.0 6.9 7.4 24.4 7.5 5.1 12.6 19.3 6.1 1.2 9.6 9.3 6.9 3.9 11.2 10.8 14.7 12.5 4.6 2.5 13.0 11.7 10.1 17.2 6.1 15.4 1.2 9.6 10.4 3.8 2.6 19.9 7.1 10.3 18.4 13.2 1.3 7.7 7.1 17.6 3.9 11.5 2.7 12.9 1.4 1.4 5.6 8.7 8.5 2.0 5.0 0.1 3.8 0.4 0.0 2.6 0.4 0.6 0.2 0.3 0.8 12.6 0.0 11.3 0.1 0.8 8.6 0.2 0.2 0.0 5.5 4.2 0.0 3.6 1.9 1.2 0.1 2.4 0.4 2.7 0.0 0.1 2.2 0.3 0.0 0.7 0.8 0.0 19.8 0.0 1.1 0.2 5.2 1.7 0.1 0.0 7.8 3.3 4.3 1.0 0.3 0.3 2.0 2.0 0.2 18.8 1.6 1.3 0.2 2.6 2.9 0.4 0.8 0.0 0.1 0.3 0.7 0.6 0.0 0.4 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.7 0.1 0.1 0.4 0.0 0.6 2.5 0.0 0.0 0.2 11.4 11.9 7.4 24.4 11.2 10.8 13.0 11.7 9.6 7.7 11.5 8.5 4.0 0.0 5.4 6.5 4.0 3.4 6.1 2.8 3.4 9.8 16.2 11.2 1.3 14.3 7.2 12.9 8.4 0.4 2.3 37.5 7.9 7.4 0.3 11.2 2.1 2.4 6.7 2.7 22.4 11.0 0.4 1.7 54.6 20.0 2.5 3.8 0.7 6.5 5.4 3.3 17.0 20.5 4.1 3.8 9.0 0.5 1.2 6.1 8.8 6.5 3.8 10.7 4.1 8.0 3.8 7.0 34.7 0.7 2.1 4.4 39.5 19.9 5.9 8.2 6.6 3.2 3.8 5.1 5.0 12.8 4.1 0.3 3.5 1.0 24.6 7.4 NOXRED1 "C14orf148, FLJ32809" ENSG00000165555 "NADP dependent oxidoreductase domain containing 1" Q6NXP6 14 77394021-77423517 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 5.9;testis: 6.9" "Group enriched" "Detected in some" 25 "Early spermatids: 137.8;Late spermatids: 125.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA055658, HPA060408" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 34: Spermatids - Unknown function" Vesicles "Plasma membrane" "HPA055658: AB_2682878, HPA060408: " "unprognostic (1.92e-2)" "unprognostic (4.83e-2)" "unprognostic (1.14e-1)" "unprognostic (1.55e-1)" "unprognostic (2.49e-2)" "unprognostic (9.87e-2)" "unprognostic (1.92e-2)" "unprognostic (1.36e-1)" "unprognostic (2.39e-2)" "unprognostic (2.61e-1)" "unprognostic (1.08e-3)" "unprognostic (1.24e-2)" "unprognostic (1.29e-2)" "unprognostic (2.60e-1)" "unprognostic (5.70e-2)" "unprognostic (1.70e-3)" "unprognostic (1.07e-3)" 0.2 0.6 0.5 0.1 0.6 0.2 0.5 0.2 0.5 0.2 1.7 0.5 0.5 0.5 0.5 0.3 0.5 0.6 0.1 0.5 0.6 0.5 0.3 0.3 0.6 0.8 1.0 0.3 0.4 0.2 0.7 0.3 0.7 0.3 0.5 5.9 0.2 0.4 0.1 1.1 0.3 0.4 0.9 0.5 0.2 6.9 0.5 0.5 0.9 0.0 0.4 0.2 0.2 0.7 0.3 0.7 0.3 0.4 0.1 0.7 0.5 0.3 0.5 0.3 0.2 0.4 0.3 0.7 0.1 0.6 0.1 0.2 0.1 0.1 0.4 0.3 0.2 0.4 0.0 0.7 0.2 0.1 0.6 0.4 0.9 0.3 0.5 0.4 0.2 0.8 0.1 0.5 0.1 0.8 0.2 0.2 0.0 0.2 0.6 0.2 0.1 0.0 0.3 0.1 0.7 0.5 0.4 0.1 0.1 0.7 0.7 0.4 0.9 0.2 0.2 0.4 0.1 0.7 0.7 0.4 0.3 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.6 0.2 0.5 0.5 0.6 0.8 1.0 0.7 0.9 0.5 0.7 0.2 0.0 0.0 5.2 0.2 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.1 0.0 0.1 0.0 4.2 0.0 0.0 0.3 0.0 0.0 137.8 0.6 0.1 0.2 1.8 0.0 4.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.1 0.0 3.0 0.0 0.0 0.3 0.2 125.8 0.9 0.3 0.0 0.0 0.0 0.4 0.0 3.0 4.4 0.1 0.0 1.2 0.1 0.1 0.3 0.1 0.2 1.5 0.0 0.0 0.1 4.1 2.2 0.0 0.0 0.0 0.0 0.2 0.1 0.1 NPAP1 C15orf2 ENSG00000185823 "Nuclear pore associated protein 1" Q9NZP6 15 24675775-24683393 "Predicted intracellular proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.8;testis: 2.9" "Cell type enriched" "Detected in some" 5 "Granulosa cells: 125.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018828, HPA019562" Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Vesicles, Plasma membrane" "HPA018828: AB_2669941, HPA019562: AB_2670190" "unprognostic (4.40e-2)" "unprognostic (1.85e-2)" "unprognostic (6.98e-3)" "unprognostic (7.45e-2)" "unprognostic (9.90e-2)" "unprognostic (1.08e-2)" "unprognostic (5.11e-3)" 0.0 0.0 0.9 0.0 1.8 0.4 0.1 0.1 1.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.5 1.7 0.9 0.0 0.0 0.1 0.9 0.7 0.5 0.4 0.0 0.5 0.0 0.5 0.1 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.5 0.1 0.1 2.9 1.5 0.0 0.5 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.9 1.8 0.1 1.1 0.5 1.7 0.9 0.7 0.5 0.5 1.5 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.1 0.2 0.7 0.1 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.1 0.0 125.9 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.0 0.8 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.3 24.1 12.7 0.0 0.0 0.0 0.0 0.5 0.0 0.2 NPC1 SLC65A1 ENSG00000141458 "NPC intracellular cholesterol transporter 1" O15118 18 23506184-23586506 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" "Host cell receptor for virus entry, Receptor" "Disease variant, Niemann-Pick disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 110.6" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 182.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 70.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 273.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026618, CAB070132, HPA077445" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Vesicles" "CAB070132: AB_10001101, HPA026618: AB_1854580, HPA077445: " "unprognostic (1.74e-1)" "unprognostic (1.53e-3)" "unprognostic (2.67e-1)" "unprognostic (1.25e-1)" "unprognostic (3.20e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (2.26e-6)" "unprognostic (1.31e-1)" "unprognostic (1.01e-2)" "unprognostic (7.36e-3)" "unprognostic (1.07e-2)" "unprognostic (1.09e-3)" "unprognostic (2.78e-2)" "unprognostic (1.89e-1)" "unprognostic (2.73e-2)" "unprognostic (1.38e-1)" "unprognostic (2.08e-3)" 17.5 76.7 35.1 16.9 69.6 42.6 20.0 55.3 47.8 16.7 28.6 13.7 14.5 16.7 15.0 20.5 13.4 15.3 11.5 41.1 44.3 16.8 15.2 29.0 20.4 73.3 55.8 16.0 11.9 72.6 15.0 27.8 66.6 13.1 12.0 28.0 36.8 13.2 22.9 24.3 17.8 15.1 49.8 17.1 20.4 13.7 55.8 12.2 11.8 14.1 15.6 15.8 18.0 110.6 21.5 41.4 17.8 29.3 55.8 44.6 40.7 37.3 81.1 38.8 84.3 28.1 30.7 18.4 28.0 55.0 132.8 59.3 22.6 63.2 35.2 15.0 17.9 6.8 35.7 63.2 79.2 25.0 28.5 42.2 61.3 81.7 273.2 76.8 40.3 20.7 20.1 47.5 44.2 32.4 10.6 14.9 12.5 24.4 37.3 15.3 28.1 45.0 88.8 51.9 7.5 14.5 44.6 62.0 54.3 27.7 15.9 19.5 50.0 81.1 15.3 32.4 32.3 29.7 97.1 12.2 177.7 21.8 37.1 4.4 9.0 8.8 29.7 8.7 20.5 5.0 12.4 20.7 4.0 6.7 5.5 15.0 7.9 10.5 13.8 70.9 17.4 10.6 35.1 69.6 55.3 47.8 41.1 44.3 73.3 55.8 66.6 49.8 55.8 110.6 18.4 25.6 56.1 32.7 9.6 9.3 34.1 16.5 8.0 6.7 10.5 9.4 4.4 11.5 21.8 9.2 18.8 15.1 61.0 24.8 0.0 11.2 1.2 23.3 12.2 16.4 3.6 2.5 23.8 15.1 7.8 13.0 15.3 53.9 10.8 31.6 6.8 9.8 28.9 3.3 20.2 7.3 2.0 11.9 6.5 1.5 9.0 21.0 12.4 59.0 7.2 15.1 25.7 39.2 182.0 34.4 22.6 10.5 15.6 41.5 8.3 5.4 10.0 12.7 0.0 10.3 14.4 13.9 25.1 17.6 14.5 23.8 19.1 52.4 7.6 64.0 NPHP4 "KIAA0673, POC10, SLSN4" ENSG00000131697 "Nephrocystin 4" O75161 1 5862811-5992473 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ciliopathy, Disease variant, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 24.2;Cone photoreceptor cells: 33.3;Excitatory neurons: 47.1;Inhibitory neurons: 30.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 2.7;hippocampal formation: 3.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063852, HPA065526" Approved Approved "Nucleoplasm,Nuclear bodies,Vesicles,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "Nuclear bodies, Vesicles" "HPA063852: , HPA065526: AB_2685505" "unprognostic (1.82e-1)" "unprognostic (1.57e-2)" "unprognostic (1.76e-1)" "unprognostic (7.30e-2)" "unprognostic (5.83e-2)" "unprognostic (2.53e-2)" "unprognostic (1.08e-2)" "unprognostic (1.95e-1)" "unprognostic (2.52e-1)" "unprognostic (1.23e-2)" "unprognostic (7.49e-3)" "unprognostic (9.00e-2)" "unprognostic (1.75e-2)" "unprognostic (2.96e-2)" "unprognostic (1.34e-1)" "unprognostic (2.54e-1)" "unprognostic (1.37e-1)" 2.7 2.2 1.0 2.3 0.8 3.7 2.7 0.0 2.7 2.9 2.5 2.2 2.1 2.8 2.3 2.0 7.9 2.1 1.9 3.1 0.0 2.2 1.3 3.0 2.3 0.0 0.0 2.9 2.4 2.7 7.8 1.6 0.0 2.2 1.2 2.4 2.2 2.3 2.2 4.9 2.1 2.2 0.0 2.2 2.0 5.3 0.0 2.5 6.7 1.9 1.1 2.1 2.5 0.0 7.8 4.8 5.4 4.3 4.7 6.8 4.1 3.9 3.9 5.3 4.2 4.1 6.5 4.0 9.6 4.6 3.6 7.4 2.7 6.6 2.7 5.1 7.3 3.4 8.1 4.1 3.7 6.5 5.1 5.6 3.2 6.3 3.9 3.4 3.8 9.4 6.2 4.1 2.4 5.9 8.3 7.1 1.0 4.0 5.5 7.1 3.4 6.5 2.6 1.0 17.0 5.5 6.1 4.5 6.5 2.3 6.0 7.2 3.7 7.6 3.2 13.0 4.8 5.0 7.0 4.2 3.4 8.3 2.0 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 1.0 0.8 0.0 2.7 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 1.1 24.2 1.3 4.0 1.2 1.8 3.4 7.3 3.0 3.6 3.1 4.3 3.9 3.7 33.3 0.6 2.2 2.1 1.9 1.6 2.0 10.2 3.3 2.9 3.6 3.2 47.1 1.8 0.5 3.5 4.1 3.0 0.0 4.0 1.8 1.5 2.0 5.0 30.8 2.2 2.0 3.5 3.7 1.4 4.1 2.4 10.6 14.0 1.8 6.3 2.1 10.6 17.3 2.1 2.2 2.2 2.6 1.8 1.1 1.9 10.9 18.2 6.6 1.6 2.7 11.6 6.5 1.9 5.3 1.1 1.7 4.0 1.7 1.1 NPL "C1orf13, DHDPS1, NPL1" ENSG00000135838 "N-acetylneuraminate pyruvate lyase" Q9BXD5 1 182789293-182830384 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 52.3;placenta: 45.2" "Cell type enhanced" "Detected in many" "Astrocytes: 170.1;Cytotrophoblasts: 123.1;Hofbauer cells: 481.5;Kupffer cells: 148.8;Microglial cells: 125.5;Proximal tubular cells: 141.0;Syncytiotrophoblasts: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 423.2" "Group enriched" "Detected in many" 34 "granulocytes: 423.2;monocytes: 128.4" "Cell line enhanced" "Detected in many" "HEL: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028345, HPA075808" Enhanced Approved "Vesicles,Plasma membrane" NA NA 190000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Plasma membrane" "HPA028345: AB_10610145, HPA075808: " "unprognostic (2.43e-2)" "unprognostic (5.71e-3)" "unprognostic (1.72e-2)" "unprognostic (1.06e-1)" "unprognostic (1.57e-1)" "unprognostic (3.06e-1)" "prognostic unfavorable (8.05e-4)" "unprognostic (4.41e-2)" "unprognostic (6.54e-3)" "unprognostic (1.45e-1)" "unprognostic (1.49e-1)" "unprognostic (6.18e-2)" "prognostic unfavorable (6.63e-4)" "unprognostic (2.11e-1)" "unprognostic (2.93e-2)" "unprognostic (2.35e-2)" "unprognostic (7.44e-2)" 12.7 5.8 16.7 19.2 20.8 18.9 5.5 19.3 22.9 4.3 11.1 6.9 2.8 1.7 29.9 10.0 3.3 13.0 2.6 12.7 15.6 52.3 20.8 14.5 32.5 19.6 20.1 1.4 2.8 3.3 1.7 45.2 18.9 2.3 9.1 1.9 4.2 6.2 1.7 8.4 4.4 7.5 15.8 28.7 5.0 5.1 27.0 6.2 2.6 2.8 14.7 15.5 5.1 22.0 3.4 0.6 1.0 0.0 2.8 2.8 0.9 1.1 2.1 1.2 0.6 0.0 1.4 9.0 1.5 0.0 0.0 1.3 1.9 2.4 0.3 0.0 1.5 14.2 0.4 0.1 1.5 5.4 8.1 2.2 9.1 0.2 0.0 0.1 0.1 10.1 10.9 13.8 2.1 1.1 0.3 3.5 11.0 7.0 1.1 1.4 0.7 11.0 0.2 7.4 3.1 4.6 5.0 0.3 4.7 1.1 2.9 8.7 0.2 1.1 2.4 0.7 0.1 9.8 12.7 9.0 2.4 9.5 3.6 25.5 128.4 104.1 5.5 118.2 4.8 1.8 4.5 4.9 7.6 6.3 3.5 4.9 423.2 0.3 96.6 1.5 8.1 65.4 16.7 20.8 19.3 22.9 12.7 15.6 19.6 20.1 18.9 15.8 27.0 22.0 2.9 0.0 5.5 170.1 4.9 6.1 4.0 8.6 1.8 7.6 1.5 4.4 2.9 2.8 4.8 7.3 2.1 123.1 2.2 2.3 19.6 1.2 19.1 0.4 0.6 3.5 1.8 45.5 7.5 2.4 6.1 2.5 3.1 0.2 5.7 0.5 72.8 3.9 481.5 6.7 13.5 1.4 6.1 148.8 11.5 27.0 0.9 91.7 10.6 125.5 40.1 2.8 5.2 22.1 21.0 1.3 0.3 0.4 0.7 1.6 0.9 141.0 1.7 2.8 0.0 1.7 1.7 16.5 8.9 16.5 7.1 107.4 3.1 3.4 1.6 4.3 NPPB ENSG00000120937 "Natriuretic peptide B" P16860 1 11857464-11858945 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Hormone, Vasoactive, Vasodilator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 767 "heart muscle: 5154.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 351.7;Ductal cells: 266.6;Pancreatic endocrine cells: 86.2" "Cancer enhanced" "Detected in some" "testis cancer: 2.2" "Group enriched" "Detected in some" 4 "basal ganglia: 3.4;cerebral cortex: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 135.5;CACO-2: 362.2;SuSa: 67.7" "Region enhanced" "Detected in single" "pons and medulla: 1.4" HPA077324 Approved Vesicles,Cytosol "Secreted to blood" NA NA 9680 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" Vesicles Cytosol "HPA077324: " "unprognostic (3.87e-1)" "unprognostic (1.29e-2)" "unprognostic (2.49e-1)" "unprognostic (4.23e-1)" "unprognostic (3.28e-2)" 1.0 0.3 0.3 0.1 3.4 0.0 0.7 0.4 1.8 0.3 0.1 0.3 0.0 0.3 0.3 0.2 0.0 0.6 5154.6 0.3 0.3 0.3 0.5 6.7 0.9 0.3 0.4 0.8 4.0 0.1 0.5 0.8 0.3 0.5 0.0 0.1 1.2 0.0 0.8 0.5 0.4 0.0 0.6 0.1 0.7 0.8 0.5 0.1 0.5 0.0 0.0 0.2 0.3 0.5 0.0 0.1 0.0 0.0 0.0 0.0 135.5 0.3 0.0 2.1 1.1 362.2 0.0 0.0 0.1 0.1 0.3 3.8 0.1 0.0 2.5 0.0 0.0 0.0 0.0 1.0 0.2 0.1 0.0 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.2 0.1 0.4 0.2 0.0 67.7 0.0 0.0 0.0 0.0 32.0 0.2 0.2 0.0 0.1 0.0 0.1 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.4 0.4 1.8 0.3 0.3 0.3 0.4 0.3 0.6 0.5 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 351.7 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 266.6 0.1 0.8 0.1 4.9 0.0 0.0 0.2 8.3 2.2 11.7 0.0 1.4 0.0 0.2 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 2.0 0.2 0.0 0.0 0.0 86.2 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 17.6 5.8 0.1 0.0 0.0 3.4 0.0 0.0 0.0 0.1 NR0B1 "AHC, AHCH, DAX1, DSS" ENSG00000169297 "Nuclear receptor subfamily 0 group B member 1" P51843 X 30304206-30309390 "Cancer-related genes, Disease related genes, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Receptor, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 32.7;testis: 19.3" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 5.4;Ionocytes: 8.2;monocytes: 2.6;Oligodendrocyte precursor cells: 10.6;Theca cells: 4.9" "Cancer enhanced" "Detected in many" "lung cancer: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "A549: 62.5;RT4: 19.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA061948, HPA067207" Supported "Nuclear speckles,Vesicles,Centriolar satellite" NA NA "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 68: Oligodendrocytes - Mixed function" "Nuclear speckles" "Vesicles, Centriolar satellite" "HPA061948: AB_2732673, HPA067207: AB_2732761" "unprognostic (1.50e-2)" "unprognostic (9.68e-2)" "unprognostic (9.47e-3)" "unprognostic (1.23e-1)" "unprognostic (2.81e-1)" "unprognostic (7.45e-3)" "unprognostic (4.83e-2)" "unprognostic (9.00e-2)" "unprognostic (1.33e-3)" 0.2 32.7 1.4 0.0 1.3 0.0 0.2 1.0 1.5 2.4 0.7 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.3 1.8 0.0 0.0 0.0 0.0 1.4 1.3 3.6 2.1 0.0 2.5 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 1.2 0.1 0.7 19.3 5.9 0.0 0.0 0.0 0.0 0.0 2.0 1.4 0.0 62.5 0.0 0.0 2.3 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 2.7 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 8.8 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.3 1.0 1.5 1.3 1.8 1.4 1.3 1.3 1.2 5.9 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.1 5.4 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.3 8.2 0.0 0.0 1.9 1.2 0.1 1.8 0.0 2.6 0.0 0.0 10.6 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.6 0.8 0.0 0.1 0.0 0.0 4.9 0.0 0.1 NR0B2 SHP ENSG00000131910 "Nuclear receptor subfamily 0 group B member 2" Q15466 1 26911489-26913975 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Receptor, Repressor" "Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 76.9;liver: 142.4" "Cell type enhanced" "Detected in some" "Cholangiocytes: 97.2;Distal tubular cells: 52.8;Exocrine glandular cells: 42.4;Gastric mucus-secreting cells: 90.2;Hepatocytes: 173.4;Proximal enterocytes: 49.8" "Cancer enriched" "Detected in many" 5 "liver cancer: 52.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 33 "Hep G2: 78.2" "Region enriched" "Detected in single" 6 "cerebellum: 1.7" "Not detected" "Not detected" HPA003983 Supported Nucleoplasm,Vesicles NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Nucleoplasm Vesicles "HPA003983: " "unprognostic (2.99e-2)" "unprognostic (1.86e-1)" "unprognostic (1.95e-3)" "unprognostic (4.68e-3)" "unprognostic (9.21e-2)" "unprognostic (8.22e-2)" "unprognostic (3.97e-2)" "unprognostic (2.44e-2)" "unprognostic (1.83e-1)" "unprognostic (3.09e-1)" "unprognostic (2.11e-2)" "unprognostic (6.74e-3)" "unprognostic (1.04e-1)" "unprognostic (2.03e-1)" "unprognostic (4.12e-3)" "unprognostic (1.10e-2)" 0.0 21.4 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.5 76.9 0.0 0.0 0.0 0.0 10.1 12.9 0.0 0.0 33.8 142.4 2.4 0.0 0.0 0.0 0.0 30.6 1.6 0.3 0.0 0.1 0.0 0.4 0.2 0.0 0.0 2.7 0.0 26.5 0.0 0.0 11.5 26.4 1.1 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 78.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.3 2.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.2 15.8 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 8.4 97.2 0.7 12.9 0.0 0.0 0.0 0.9 52.8 31.3 0.4 0.1 0.0 0.2 24.4 8.0 0.0 42.4 0.0 0.3 90.2 0.0 0.0 3.0 2.5 173.4 0.1 28.6 0.0 7.6 16.2 3.8 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 15.2 0.3 0.0 0.2 0.0 49.8 0.1 0.0 0.4 0.0 0.0 0.2 0.8 0.1 0.0 0.0 0.0 0.3 0.1 11.0 0.2 NR1H2 "LXR-b, LXRb, NER, NER-I, RIP15, UNR" ENSG00000131408 "Nuclear receptor subfamily 1 group H member 2" P55055 19 50329653-50383388 "Cancer-related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005446, HPA056838, HPA070212" Uncertain Enhanced Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm Vesicles "HPA005446: , HPA056838: AB_2683254, HPA070212: AB_2686234" "unprognostic (1.31e-1)" "unprognostic (5.35e-2)" "prognostic unfavorable (9.86e-4)" "unprognostic (1.34e-3)" "unprognostic (1.68e-1)" "unprognostic (5.24e-3)" "unprognostic (2.26e-2)" "unprognostic (9.69e-2)" "unprognostic (6.45e-2)" "unprognostic (5.23e-2)" "unprognostic (2.40e-1)" "unprognostic (1.88e-1)" "unprognostic (2.69e-2)" "unprognostic (1.86e-1)" "unprognostic (1.35e-1)" "unprognostic (5.12e-2)" "unprognostic (1.69e-3)" 59.6 61.4 43.2 37.1 45.6 143.4 57.9 43.1 53.3 61.1 41.3 78.7 43.1 67.3 10.8 56.0 63.6 28.4 89.6 40.7 45.0 63.9 61.0 66.4 33.9 55.8 47.3 56.9 49.8 32.1 40.6 26.3 48.5 63.7 11.9 9.4 46.9 37.9 132.1 60.7 55.1 20.3 44.4 56.7 60.2 31.8 48.4 21.4 56.5 36.7 16.7 77.1 58.3 47.8 56.2 124.1 12.1 32.4 34.5 36.4 42.0 75.8 53.4 38.4 41.7 25.8 48.9 34.8 67.1 39.4 31.7 46.8 7.8 34.1 9.5 89.9 57.6 32.5 41.8 26.4 63.7 58.2 84.0 34.8 45.2 39.3 27.3 37.7 33.4 24.7 51.7 65.4 20.8 53.2 39.3 40.5 25.5 32.2 94.4 22.8 35.8 57.2 30.4 54.3 14.9 50.6 50.9 54.0 46.7 6.6 37.9 42.5 53.9 54.3 45.3 58.4 66.8 82.5 79.3 26.4 108.6 36.5 53.8 159.1 123.9 232.4 90.4 125.4 89.3 112.3 89.9 86.2 121.3 117.7 90.8 81.4 194.8 85.9 146.4 103.9 89.0 129.3 43.2 45.6 43.1 53.3 40.7 45.0 55.8 47.3 48.5 44.4 48.4 47.8 50.7 28.9 30.7 3.6 70.7 43.0 89.3 53.2 32.5 37.9 33.4 27.3 29.6 37.1 31.1 31.3 14.6 64.5 57.0 82.1 64.6 63.6 15.5 31.9 19.5 50.0 20.8 58.9 5.9 72.6 53.3 40.2 37.2 33.8 50.2 25.1 36.8 20.7 51.3 37.0 5.5 45.5 46.8 37.0 48.3 9.5 45.4 54.5 60.5 4.7 65.2 46.8 65.9 0.5 6.9 74.3 89.6 53.4 47.5 91.0 93.5 61.8 21.7 25.4 39.5 45.5 50.2 34.6 25.9 27.9 45.7 140.0 54.8 27.7 35.7 109.0 NRAP ENSG00000197893 "Nebulin related anchoring protein" Q86VF7 10 113588714-113664070 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "skeletal muscle: 2363.9;tongue: 1144.8" "Cell type enriched" "Detected in some" 9 "Cardiomyocytes: 534.1" "Group enriched" "Detected in some" 7 "head and neck cancer: 8.2;prostate cancer: 3.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA037953, HPA037954, HPA075074" Enhanced Approved "Vesicles,Intermediate filaments,Cytosol" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Intermediate filaments" "Vesicles, Cytosol" "HPA037953: AB_2675755, HPA037954: AB_10672394, HPA075074: " "unprognostic (1.13e-1)" "unprognostic (2.95e-1)" "unprognostic (3.61e-2)" "unprognostic (2.05e-2)" "unprognostic (5.75e-2)" "unprognostic (1.97e-2)" "unprognostic (1.25e-2)" "unprognostic (3.03e-3)" "unprognostic (3.72e-2)" "unprognostic (4.20e-2)" "unprognostic (6.40e-2)" "unprognostic (2.88e-1)" "unprognostic (5.39e-4)" "unprognostic (8.21e-2)" "unprognostic (1.16e-1)" "unprognostic (3.16e-1)" 0.3 0.1 0.1 0.0 0.5 0.0 0.4 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 24.8 0.0 0.2 428.6 0.2 0.0 0.1 0.5 0.4 0.1 0.0 0.2 0.1 0.4 0.0 0.3 0.0 0.0 20.4 1.0 0.0 22.1 0.0 2363.9 0.8 0.1 0.0 0.0 0.1 0.3 0.6 0.3 0.0 0.4 1144.8 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.4 0.2 0.0 0.0 0.2 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.3 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.0 534.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 1.4 0.1 0.0 3.7 0.0 0.0 0.3 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 4.8 0.0 0.0 0.3 2.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 57.3 3.3 1.0 2.3 0.0 0.1 0.0 0.2 0.0 0.5 0.0 NRCAM "Bravo, KIAA0343" ENSG00000091129 "Neuronal cell adhesion molecule" Q92823 7 108147623-108456717 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 37.3;brain: 38.3;epididymis: 34.4;retina: 38.0" "Group enriched" "Detected in many" 7 "Astrocytes: 612.5;Excitatory neurons: 764.5;Inhibitory neurons: 392.4;Oligodendrocyte precursor cells: 1259.2" "Cancer enriched" "Detected in all" 7 "glioma: 57.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "naive CD8 T-cell: 2.0" "Lineage enriched" "Detected in single" 15 "T-cells: 2.0" "Cell line enhanced" "Detected in many" "A549: 99.6;AF22: 94.8;EFO-21: 175.4;HMC-1: 187.9;SH-SY5Y: 115.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012606 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted in brain" NA NA 110000000 "Cluster 32: T-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Vesicles, Plasma membrane" "HPA012606: AB_1854636" "unprognostic (2.66e-1)" "unprognostic (2.65e-1)" "unprognostic (2.52e-3)" "unprognostic (2.18e-2)" "unprognostic (4.08e-3)" "unprognostic (1.01e-2)" "unprognostic (4.47e-3)" "unprognostic (1.66e-1)" "unprognostic (1.73e-1)" "unprognostic (4.81e-2)" "unprognostic (9.10e-3)" "unprognostic (4.33e-2)" "unprognostic (2.22e-2)" "unprognostic (9.70e-3)" "unprognostic (6.42e-2)" "unprognostic (6.51e-3)" "unprognostic (3.28e-2)" 3.1 37.3 19.8 1.8 31.9 0.3 1.5 2.4 34.6 5.0 0.0 0.8 0.7 2.1 34.4 0.7 3.6 7.3 0.4 33.1 9.4 6.2 0.4 2.3 0.8 2.3 22.7 1.5 29.4 7.3 11.4 7.8 2.0 0.8 0.7 38.0 1.9 14.2 0.2 0.8 0.6 0.7 1.5 4.8 1.8 1.7 38.3 2.8 4.1 0.4 2.7 0.5 0.4 2.6 0.1 99.6 94.8 0.0 11.4 2.2 1.8 0.7 0.4 1.0 1.7 40.7 0.0 0.0 175.4 0.7 1.5 0.4 2.2 1.6 1.0 0.1 12.7 0.0 0.7 1.0 0.2 0.9 187.9 15.5 0.0 0.2 0.6 0.2 61.7 0.2 0.2 0.8 1.5 38.2 0.4 0.3 13.1 60.1 0.0 0.0 27.8 33.3 21.4 0.1 18.6 115.9 1.3 0.0 1.9 3.3 0.2 0.1 66.2 4.2 1.0 0.1 16.4 0.2 0.5 0.9 0.7 0.1 55.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.2 19.8 31.9 2.4 34.6 33.1 9.4 2.3 22.7 2.0 1.5 38.3 2.6 0.2 0.0 0.0 612.5 0.8 0.4 0.1 0.8 1.2 66.2 1.5 0.9 0.7 7.2 0.1 5.5 102.2 3.6 0.0 0.2 3.9 1.6 37.3 10.4 2.4 1.3 0.0 0.0 764.5 12.1 0.2 2.0 3.6 25.0 23.4 4.4 1.4 0.4 0.8 13.5 392.4 0.3 0.0 0.8 0.4 8.3 0.9 0.2 3.6 51.5 0.6 45.1 0.0 1259.2 21.9 3.7 0.0 0.4 2.6 1.2 0.0 3.3 0.1 8.8 0.0 1.0 2.6 1.1 2.7 0.2 0.1 4.4 1.1 34.2 0.0 0.0 NREP "C5orf13, D4S114, P311, PRO1873, PTZ17, SEZ17" ENSG00000134986 "Neuronal regeneration related protein" Q16612 5 111662621-111997464 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 118.3;Excitatory neurons: 116.1;Theca cells: 150.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "myeloid DC: 24.6;NK-cell: 6.9;plasmacytoid DC: 25.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 425.3;SH-SY5Y: 461.8" "Region enriched" "Detected in all" 5 "cerebellum: 1766.0" "Region enhanced" "Detected in all" "cerebellum: 219.5" HPA000545 Approved Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA000545: AB_1845721" "unprognostic (2.85e-2)" "unprognostic (1.00e-2)" "unprognostic (2.30e-1)" "unprognostic (1.48e-3)" "unprognostic (4.37e-1)" "unprognostic (2.26e-1)" "unprognostic (8.16e-3)" "unprognostic (1.58e-1)" "unprognostic (6.45e-3)" "unprognostic (1.32e-1)" "unprognostic (3.76e-2)" "unprognostic (2.02e-1)" "unprognostic (4.44e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (2.84e-2)" "unprognostic (3.47e-3)" "unprognostic (5.76e-3)" 18.9 56.5 50.1 19.4 52.6 36.7 29.3 141.8 71.6 32.3 56.9 28.6 16.9 84.8 17.9 23.0 18.2 65.4 70.9 52.5 44.0 49.5 50.7 27.7 17.3 47.8 52.1 41.8 9.8 8.4 13.3 119.8 50.8 52.7 25.2 107.4 36.1 72.2 179.9 22.1 16.7 54.6 44.6 36.9 25.7 12.7 46.4 168.1 18.6 118.2 18.4 27.5 16.8 54.7 0.6 7.1 425.3 91.5 20.2 46.6 20.3 140.9 83.9 135.7 221.0 0.8 2.8 73.1 44.6 71.3 18.9 0.3 91.0 5.2 69.4 29.5 13.0 57.5 35.2 77.6 28.1 77.0 0.8 45.6 22.5 129.5 44.5 318.6 154.2 81.4 0.6 7.4 143.4 1.6 308.3 53.7 244.1 0.2 33.3 326.3 173.4 19.9 52.2 1.6 96.9 461.8 31.6 2.2 2.9 224.2 17.7 210.6 31.1 163.7 54.1 80.8 15.8 34.6 29.3 92.3 35.6 159.8 32.8 0.0 4.0 0.0 0.0 2.2 0.0 1.6 0.1 0.2 24.6 1.1 1.2 1.6 0.1 6.9 1.0 25.1 0.0 2.2 50.1 52.6 141.8 71.6 52.5 44.0 47.8 52.1 50.8 44.6 46.4 54.7 20.8 6.4 30.8 43.1 3.6 18.1 1.6 4.5 14.2 66.9 12.4 22.6 33.4 8.6 5.7 12.9 87.6 118.3 12.9 2.5 33.2 14.4 2.5 5.4 69.1 38.9 21.6 52.2 116.1 5.5 18.6 31.7 31.1 7.4 5.1 69.9 27.5 10.1 35.5 20.2 51.4 9.3 42.7 10.0 19.0 1.0 8.4 14.9 14.2 17.8 11.5 14.9 5.2 37.2 4.6 8.2 2.0 23.3 0.9 0.7 1.2 61.0 0.5 29.0 13.1 25.4 51.8 0.8 12.6 11.9 12.6 31.5 3.2 150.8 11.3 0.2 NRG3 ENSG00000185737 "Neuregulin 3" P56975 10 81875194-82987179 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 17.3;retina: 5.2" "Group enriched" "Detected in some" 18 "Astrocytes: 2921.6;Excitatory neurons: 3761.0;Inhibitory neurons: 3088.3;Oligodendrocyte precursor cells: 1175.2" "Cancer enhanced" "Detected in many" "melanoma: 2.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.3;SK-MEL-30: 2.7;U-2 OS: 2.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075789 Uncertain Vesicles "Secreted in brain" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA075789: " "unprognostic (6.15e-3)" "unprognostic (2.43e-2)" "unprognostic (1.65e-5)" "unprognostic (1.89e-1)" "unprognostic (7.03e-4)" "unprognostic (1.85e-2)" "unprognostic (1.06e-1)" "unprognostic (7.05e-2)" "unprognostic (9.33e-2)" "unprognostic (1.82e-1)" "unprognostic (1.21e-1)" "unprognostic (3.75e-2)" "unprognostic (3.31e-4)" "unprognostic (1.04e-1)" "unprognostic (7.68e-3)" "unprognostic (7.27e-4)" 0.1 0.4 16.4 0.3 11.4 0.0 1.3 0.0 17.3 0.1 0.0 0.4 0.1 0.0 0.0 0.1 4.7 2.8 0.4 16.1 2.6 0.7 0.5 0.7 0.1 1.2 6.3 0.0 0.1 0.1 2.0 0.3 0.4 0.1 0.1 5.2 2.6 0.2 0.0 0.6 0.1 0.1 2.5 0.1 0.3 1.8 9.9 0.0 0.2 0.1 0.0 0.1 0.0 3.5 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 2.7 0.2 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.4 11.4 0.0 17.3 16.1 2.6 1.2 6.3 0.4 2.5 9.9 3.5 0.1 0.0 0.0 2921.6 0.1 0.0 0.0 0.0 0.0 15.9 0.7 0.6 0.8 2.8 0.0 0.0 2.1 0.0 0.1 0.0 0.0 0.9 31.4 0.0 0.0 0.7 0.0 0.0 3761.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 3088.3 0.0 0.0 0.0 0.0 12.8 0.6 0.1 0.0 148.0 0.0 6.7 0.0 1175.2 50.2 0.2 0.0 0.7 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.2 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 NRP2 VEGF165R2 ENSG00000118257 "Neuropilin 2" O60462 2 205681990-205798133 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 78.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 134.4;Hepatic stellate cells: 137.8;Hofbauer cells: 141.3;Langerhans cells: 129.8;monocytes: 224.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 123.6;HUVEC TERT2: 105.7;TIME: 106.3;U-251 MG: 217.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039980, HPA054974" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted in other tissues" NA NA 29000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA039980: AB_10795517, HPA054974: AB_2682657" "unprognostic (4.28e-2)" "unprognostic (1.17e-1)" "unprognostic (8.12e-3)" "unprognostic (3.38e-1)" "unprognostic (1.62e-1)" "unprognostic (1.57e-2)" "unprognostic (9.36e-2)" "unprognostic (3.70e-1)" "unprognostic (2.15e-3)" "unprognostic (2.90e-2)" "unprognostic (2.56e-3)" "unprognostic (4.17e-1)" "prognostic unfavorable (7.68e-7)" "unprognostic (2.22e-3)" "unprognostic (5.45e-2)" "unprognostic (6.41e-3)" "prognostic unfavorable (7.80e-5)" 18.8 22.2 18.0 17.8 13.8 4.6 12.6 9.3 11.7 18.8 7.0 78.7 5.3 51.8 3.7 13.3 21.1 31.1 6.3 21.7 42.5 4.9 9.6 24.3 8.2 30.4 23.9 46.8 1.9 2.5 9.6 47.0 19.6 13.0 10.5 3.6 3.3 30.9 2.3 4.8 14.9 54.8 13.2 7.5 25.9 1.4 33.9 6.1 10.8 3.4 4.5 38.3 15.9 12.4 2.5 50.4 32.2 0.2 30.1 9.6 9.3 8.5 14.8 10.0 9.5 48.0 123.6 0.0 11.9 25.3 20.5 19.2 1.5 15.9 16.8 0.1 6.8 0.5 2.4 0.4 80.7 0.0 2.1 68.5 12.2 14.4 12.3 64.5 105.7 0.2 0.2 0.1 6.8 0.2 0.0 0.0 41.5 0.1 9.2 0.2 2.0 12.0 21.7 0.0 29.0 1.0 1.1 0.3 75.4 84.9 0.1 0.8 106.3 43.1 0.4 11.3 217.0 0.0 0.2 3.2 96.9 0.3 88.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.0 13.8 9.3 11.7 21.7 42.5 30.4 23.9 19.6 13.2 33.9 12.4 88.7 89.8 57.5 2.0 3.8 19.4 19.5 30.8 97.9 36.5 1.3 11.3 4.5 5.7 53.2 1.8 0.0 89.7 0.1 0.6 0.0 6.4 6.3 8.8 8.1 134.4 1.2 2.7 4.1 3.8 8.7 47.0 1.5 13.2 3.8 2.7 137.8 1.8 141.3 0.0 9.4 1.1 4.1 28.0 129.8 18.9 2.8 53.7 19.6 53.4 224.8 4.8 0.0 4.0 8.1 53.2 0.0 4.9 0.2 9.1 0.0 0.6 48.1 2.7 0.0 4.6 32.2 1.4 1.4 17.8 12.6 25.7 2.4 48.1 0.4 51.5 NRSN2 "C20orf98, dJ1103G7.6" ENSG00000125841 "Neurensin 2" Q9GZP1 20 346782-359660 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 154.7" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 29.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015967 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" Vesicles "Nucleoplasm, Cytosol" "HPA015967: AB_1854647" "unprognostic (5.67e-2)" "unprognostic (3.47e-1)" "unprognostic (7.50e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (4.05e-2)" "unprognostic (4.48e-2)" "unprognostic (1.48e-1)" "unprognostic (4.96e-2)" "unprognostic (5.92e-2)" "prognostic favorable (1.61e-4)" "unprognostic (6.96e-2)" "unprognostic (1.96e-3)" "unprognostic (2.94e-2)" "unprognostic (1.96e-1)" "unprognostic (7.85e-3)" "unprognostic (1.73e-3)" 19.9 57.0 105.7 10.5 114.4 1.7 17.4 87.8 154.7 30.1 71.3 28.3 6.0 32.5 25.9 9.7 27.9 15.4 30.9 114.3 100.6 33.0 4.8 22.4 7.5 94.4 92.0 36.0 20.3 42.6 60.4 16.9 93.9 28.3 9.7 56.9 21.1 25.5 3.4 11.4 13.1 27.5 80.5 16.8 20.2 30.6 96.6 5.5 28.1 5.7 7.2 23.5 18.2 102.9 56.5 68.3 40.2 37.7 53.0 58.4 15.2 37.4 72.3 66.3 66.8 38.2 1.2 0.0 12.6 70.7 48.9 24.1 33.5 5.8 42.4 0.3 33.0 20.8 32.5 70.7 53.5 0.6 3.3 67.4 4.5 48.2 8.1 54.1 46.4 0.3 40.3 35.1 59.2 10.0 0.9 17.9 31.3 0.7 34.9 32.4 22.1 2.7 67.4 0.3 80.8 58.0 44.9 13.0 64.9 26.5 53.2 19.7 31.0 70.6 36.4 2.6 45.6 6.5 1.4 14.7 9.5 0.6 36.7 0.0 0.7 1.2 2.4 0.3 0.7 5.6 0.8 2.6 1.5 6.9 1.0 1.8 0.0 2.8 0.3 3.5 0.6 1.1 105.7 114.4 87.8 154.7 114.3 100.6 94.4 92.0 93.9 80.5 96.6 102.9 3.8 0.0 3.1 16.0 2.2 3.2 3.6 8.5 7.4 26.5 5.8 5.0 5.5 1.5 6.1 12.9 2.1 7.3 0.5 2.6 1.9 14.7 9.6 4.7 12.0 6.9 29.4 1.3 21.0 1.6 6.8 10.4 3.1 3.9 5.1 7.6 5.7 0.3 3.2 16.8 27.1 2.6 4.1 0.9 2.2 14.4 13.1 0.7 3.6 2.8 2.1 17.3 2.1 12.1 5.9 2.9 1.8 10.5 2.6 3.3 0.2 7.8 3.6 15.4 19.7 4.9 9.2 21.3 12.8 1.4 2.3 4.4 1.4 12.9 2.2 2.9 NSMCE1 NSE1 ENSG00000169189 "NSE1 homolog, SMC5-SMC6 complex component" Q8WV22 16 27224994-27268772 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "granulocytes: 275.5;Late spermatids: 420.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041567, HPA043091" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" "HPA041567: AB_10964260, HPA043091: AB_10962722" "unprognostic (6.27e-2)" "unprognostic (8.17e-2)" "unprognostic (2.52e-2)" "unprognostic (2.48e-3)" "unprognostic (4.17e-1)" "unprognostic (4.52e-3)" "unprognostic (1.59e-1)" "unprognostic (1.06e-1)" "unprognostic (1.79e-1)" "unprognostic (1.22e-1)" "unprognostic (1.93e-1)" "unprognostic (9.91e-2)" "unprognostic (1.40e-1)" "unprognostic (5.45e-3)" "unprognostic (3.58e-1)" "unprognostic (1.46e-1)" "unprognostic (1.29e-1)" 43.8 68.3 58.8 32.2 61.7 35.1 52.5 65.2 71.7 43.3 66.0 53.1 25.3 42.3 55.0 45.5 62.2 35.8 47.6 57.4 63.3 58.3 55.9 42.4 54.5 65.5 61.4 45.0 59.3 86.1 37.3 37.3 64.6 57.4 36.8 24.9 46.2 51.7 45.2 40.7 37.0 45.2 64.0 33.5 51.3 79.8 61.3 56.4 53.0 44.9 54.7 51.4 39.1 67.0 56.5 80.6 53.8 58.6 85.8 114.2 43.1 58.9 60.4 44.5 46.1 62.7 134.1 110.0 137.7 91.1 45.7 59.5 101.9 178.6 57.3 136.3 70.6 51.0 68.6 122.1 149.1 59.9 37.4 112.6 122.3 111.7 211.5 127.8 60.3 104.3 69.6 33.8 82.9 96.7 80.0 67.5 46.8 94.0 54.7 69.1 65.8 174.7 129.9 36.3 56.4 51.0 40.2 55.9 104.3 65.1 92.3 71.9 37.8 53.3 33.2 61.1 57.8 101.0 78.1 85.9 114.0 59.4 23.3 125.3 91.2 86.2 78.9 81.6 86.3 84.2 111.1 95.7 128.4 133.1 126.7 99.7 29.6 213.8 81.5 124.6 113.0 120.3 58.8 61.7 65.2 71.7 57.4 63.3 65.5 61.4 64.6 64.0 61.3 67.0 34.8 35.3 36.4 8.5 38.1 28.3 57.6 110.7 33.0 14.9 60.7 83.8 49.6 62.9 58.5 44.1 2.1 126.2 41.2 45.6 129.1 79.2 209.9 40.3 32.9 33.9 58.7 24.0 5.4 73.0 63.3 44.5 17.3 29.6 275.5 37.4 52.8 64.0 83.2 13.5 6.7 65.8 44.7 53.3 45.6 420.8 24.2 39.5 46.2 12.2 98.1 64.7 43.3 12.5 14.8 40.1 45.7 39.9 28.1 49.0 83.9 173.8 94.6 18.8 26.3 58.1 50.1 119.0 39.4 43.5 32.7 64.3 55.3 39.9 46.7 48.3 NSUN7 FLJ14001 ENSG00000179299 "NOP2/Sun RNA methyltransferase family member 7" Q8NE18 4 40749925-40811184 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 16.5" "Cell type enhanced" "Detected in many" "Early spermatids: 47.5;Late spermatids: 75.6;Respiratory ciliated cells: 36.4;Spermatocytes: 38.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.7" "Cell line enhanced" "Detected in some" "A-431: 2.6;CAPAN-2: 5.5;Karpas-707: 4.0;MCF7: 2.6;SuSa: 3.0;T-47d: 3.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA020653 Uncertain Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA020653: AB_1848710" "unprognostic (2.32e-1)" "unprognostic (4.22e-1)" "unprognostic (4.77e-2)" "unprognostic (1.50e-1)" "unprognostic (2.79e-2)" "unprognostic (1.47e-1)" "unprognostic (1.63e-1)" "unprognostic (4.01e-3)" "unprognostic (4.37e-2)" "unprognostic (3.06e-1)" "unprognostic (2.24e-1)" "unprognostic (8.42e-2)" "prognostic favorable (2.76e-8)" "unprognostic (3.69e-2)" "unprognostic (1.15e-1)" "unprognostic (1.12e-1)" "unprognostic (1.04e-2)" 0.6 0.9 0.6 1.0 0.6 0.6 3.8 0.4 0.4 2.5 7.2 2.8 1.7 2.2 2.7 1.8 6.8 1.2 2.1 0.5 1.5 4.7 0.4 3.3 0.3 1.8 2.4 2.3 7.2 3.3 3.6 1.3 1.5 4.5 2.4 0.7 4.8 1.5 0.0 1.5 2.1 1.2 1.2 2.7 3.2 16.5 2.0 0.3 4.7 0.2 0.3 1.3 1.2 0.8 2.6 0.1 1.2 0.0 0.0 0.0 1.7 0.0 0.2 0.1 0.1 1.0 5.5 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 2.6 0.1 0.0 1.4 0.0 0.3 0.1 0.0 0.0 2.4 0.7 0.6 1.5 0.3 1.7 0.0 3.0 3.9 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.4 0.4 0.5 1.5 1.8 2.4 1.5 1.2 2.0 0.8 0.1 9.6 7.8 3.6 4.3 1.1 3.1 1.5 2.2 0.1 8.6 7.1 3.5 0.0 10.5 9.2 0.0 9.2 0.1 2.7 9.8 5.8 47.5 20.7 0.9 0.6 8.3 0.4 0.7 5.4 3.6 1.2 4.6 5.4 0.0 8.5 0.7 0.2 3.8 0.0 0.9 7.1 4.1 0.8 0.4 75.6 1.5 2.2 0.0 8.4 1.0 2.1 0.0 18.1 1.3 4.7 2.7 0.0 0.3 4.5 2.2 5.5 36.4 0.1 0.0 0.4 0.8 38.9 11.4 8.2 1.0 4.5 0.7 3.4 7.7 5.7 NTAQ1 "C8orf32, FLJ10204, WDYHV1" ENSG00000156795 "N-terminal glutamine amidase 1" Q96HA8 8 123416726-123470028 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 5.5;Cardiomyocytes: 21.9;Cytotrophoblasts: 13.9;Extravillous trophoblasts: 23.0;Hofbauer cells: 13.2;Syncytiotrophoblasts: 10.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 109.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024823, HPA053680" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Vesicles "HPA024823: AB_1845773, HPA053680: AB_2682228" "unprognostic (9.97e-2)" "unprognostic (4.82e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (4.93e-5)" "unprognostic (1.69e-1)" "unprognostic (5.00e-2)" "prognostic unfavorable (3.47e-4)" "unprognostic (1.93e-2)" "unprognostic (1.20e-1)" "unprognostic (1.90e-1)" "unprognostic (1.19e-1)" "unprognostic (5.79e-2)" "unprognostic (2.81e-2)" "unprognostic (1.26e-1)" "unprognostic (5.39e-2)" "unprognostic (7.46e-2)" "unprognostic (2.37e-1)" 7.1 10.9 16.2 5.1 16.7 5.9 13.5 16.3 24.0 12.8 15.5 7.5 4.3 8.1 8.9 6.9 7.5 6.7 20.1 14.8 17.8 13.0 6.8 6.8 7.4 17.0 17.9 18.2 9.6 11.0 10.5 6.8 17.4 10.2 7.9 14.9 6.9 8.8 16.0 7.7 4.4 9.5 15.8 5.2 8.5 12.7 20.0 7.1 12.8 17.6 10.1 8.8 7.2 17.7 26.6 26.9 39.2 18.1 15.3 40.9 14.5 19.1 21.3 23.4 26.1 15.8 17.8 19.7 19.8 23.8 32.7 12.8 25.8 29.7 31.4 53.1 15.8 25.6 13.2 22.4 21.2 12.7 10.9 24.1 16.0 29.3 32.8 27.1 22.6 41.2 18.8 29.0 33.5 84.3 30.2 14.4 12.3 65.6 20.5 13.5 20.0 20.4 31.1 22.6 18.6 34.1 20.7 109.0 35.8 44.5 17.6 12.2 9.8 26.5 46.2 19.7 26.4 17.4 38.1 24.1 18.8 14.1 19.1 16.3 5.7 2.1 6.2 8.7 7.4 5.0 7.3 7.7 9.0 4.1 6.2 6.9 1.5 16.0 3.8 5.2 10.6 4.6 16.2 16.7 16.3 24.0 14.8 17.8 17.0 17.9 17.4 15.8 20.0 17.7 5.5 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.0 13.9 2.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 23.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 10.0 0.3 0.0 0.0 0.0 NTF3 NGF2 ENSG00000185652 "Neurotrophin 3" P20783 12 5432108-5521536 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 18.5;Basal prostatic cells: 36.6;Basal squamous epithelial cells: 89.4;Prostatic glandular cells: 20.5;Sertoli cells: 32.9;Smooth muscle cells: 24.0" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.2" "Group enriched" "Detected in some" 5 "cerebellum: 3.4;cerebral cortex: 1.3;hippocampal formation: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 11.4;BJ hTERT+ SV40 Large T+: 14.8;BJ hTERT+ SV40 Large T+ RasG12V: 19.7;HBF TERT88: 18.0;RT4: 8.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "cerebellum: 4.7;cerebral cortex: 2.0;hippocampal formation: 2.2" HPA032001 Uncertain Approved Vesicles "Secreted in other tissues" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "HPA032001: AB_2674106" "unprognostic (3.04e-2)" "unprognostic (7.46e-2)" "unprognostic (7.33e-3)" "unprognostic (4.66e-3)" "unprognostic (8.89e-2)" "unprognostic (1.08e-2)" "unprognostic (1.36e-3)" "unprognostic (7.68e-2)" "unprognostic (1.35e-1)" "unprognostic (2.14e-1)" "unprognostic (1.86e-1)" "unprognostic (2.20e-1)" "unprognostic (7.77e-4)" "unprognostic (4.02e-3)" "unprognostic (1.92e-1)" "unprognostic (8.06e-3)" "unprognostic (4.51e-3)" 4.2 1.8 0.2 0.7 0.4 0.0 2.7 3.4 1.3 6.6 0.2 1.8 1.9 1.9 2.0 3.4 2.9 1.8 3.1 1.2 0.3 2.6 7.7 1.6 0.3 0.4 0.2 11.1 0.2 0.1 1.0 1.9 0.3 3.6 1.0 0.1 3.1 2.4 1.8 3.2 2.5 0.9 0.3 4.5 2.5 0.8 0.1 0.4 0.9 1.0 0.4 4.6 7.0 0.2 1.9 0.0 6.7 0.0 0.0 0.0 0.0 4.5 11.4 14.8 19.7 0.1 0.2 0.0 6.7 7.3 0.0 2.4 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 4.5 4.7 8.5 0.3 0.0 0.0 0.1 0.0 3.9 0.0 0.0 0.0 0.0 3.1 0.2 0.0 0.2 0.1 0.9 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 3.4 1.3 1.2 0.3 0.4 0.2 0.3 0.3 0.1 0.2 1.0 0.0 0.0 0.0 0.0 18.5 36.6 0.7 89.4 0.0 0.2 10.3 0.9 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.1 0.2 0.2 1.4 0.0 0.0 0.1 0.0 0.1 6.1 0.0 0.1 0.0 0.0 5.0 2.1 0.0 0.0 1.2 0.1 0.0 0.0 2.1 0.1 8.4 0.3 7.2 3.7 0.0 0.0 0.0 0.0 0.0 0.0 1.1 10.9 0.0 20.5 0.2 0.0 0.8 0.0 32.9 6.8 24.0 0.5 0.8 5.0 3.3 0.1 0.5 0.5 0.2 6.9 NTRK1 "MTC, TRK, TRKA" ENSG00000198400 "Neurotrophic receptor tyrosine kinase 1" P04629 1 156815640-156881850 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 7.0;brain: 21.7" "Group enriched" "Detected in some" 10 "Bipolar cells: 22.8;granulocytes: 55.9;Horizontal cells: 57.2" "Cancer enhanced" "Detected in some" "glioma: 1.3" "Group enriched" "Detected in many" 6 "cerebral cortex: 7.6;medulla oblongata: 19.8;pons: 21.7" "Immune cell enriched" "Detected in single" 116 "basophil: 94.5" "Lineage enriched" "Detected in single" 768 "granulocytes: 94.5" "Cell line enriched" "Detected in some" 4 "HMC-1: 82.1" "Region enhanced" "Detected in many" "basal ganglia: 8.4" "Region enriched" "Detected in single" 6 "basal ganglia: 4.1" "CAB004606, HPA035799, HPA076570" Approved Approved Vesicles,Cytosol NA NA 79000 "Cluster 38: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 62: Horizontal cells - Visual perception" "Vesicles, Cytosol" "CAB004606: AB_628397, HPA035799: AB_2674788, HPA076570: " "unprognostic (5.89e-3)" "unprognostic (7.56e-2)" "unprognostic (2.74e-2)" "unprognostic (5.99e-3)" "unprognostic (7.26e-2)" "unprognostic (1.43e-3)" "unprognostic (1.56e-1)" "unprognostic (7.42e-3)" "unprognostic (7.63e-2)" "unprognostic (1.35e-1)" "unprognostic (6.73e-2)" "unprognostic (2.29e-2)" "unprognostic (3.18e-11)" "unprognostic (2.18e-3)" "unprognostic (3.79e-2)" "unprognostic (1.07e-1)" "unprognostic (4.89e-1)" 0.8 7.0 0.7 0.4 1.8 0.7 0.2 1.8 7.6 0.7 0.7 0.8 0.5 1.0 0.0 0.1 0.5 0.4 1.0 0.3 2.8 3.0 0.0 0.5 0.1 19.8 1.5 0.1 0.2 0.0 0.7 0.2 21.7 1.4 0.0 1.9 0.5 0.3 0.4 0.1 0.3 0.6 0.2 0.1 0.5 1.6 0.4 0.3 0.2 0.2 0.0 0.3 0.5 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.1 0.0 0.0 0.0 11.9 0.0 14.0 0.0 0.0 0.0 0.0 82.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.4 1.6 0.0 0.2 0.0 2.4 0.2 0.0 1.5 2.5 0.0 0.2 0.0 0.5 1.5 18.2 0.0 0.1 0.0 0.3 0.0 0.1 0.3 0.0 1.1 0.0 0.0 3.5 0.6 0.0 0.0 0.0 0.1 94.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.7 1.8 1.8 7.6 0.3 2.8 19.8 1.5 21.7 0.2 0.4 0.6 0.1 0.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.6 0.2 0.0 4.2 0.7 0.0 0.0 4.3 0.0 0.1 55.9 0.0 0.0 0.0 0.1 57.2 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.8 0.0 0.5 0.0 0.5 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.9 3.2 2.7 0.0 0.1 0.0 1.0 0.1 0.0 0.0 NTS ENSG00000133636 Neurotensin P30990 12 85874295-85882992 "Predicted secreted proteins" Vasoactive "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 165.8" "Cell type enriched" "Detected in some" 13 "Intestinal goblet cells: 1683.2" "Cancer enhanced" "Detected in many" "lung cancer: 155.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SuSa: 205.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 154.3" "HPA026664, HPA071012" Enhanced Supported Vesicles "Secreted to digestive system" NA NA 1600000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 27: Mucus-secreting cells - Mucin production" Vesicles "HPA026664: AB_2671936, HPA071012: " "unprognostic (3.63e-1)" "prognostic favorable (9.94e-5)" "unprognostic (8.18e-2)" "prognostic unfavorable (5.10e-4)" "unprognostic (1.99e-2)" "unprognostic (3.04e-1)" "unprognostic (7.62e-2)" "unprognostic (2.43e-1)" "unprognostic (1.53e-3)" "unprognostic (8.83e-2)" "unprognostic (1.74e-2)" "unprognostic (3.76e-2)" "unprognostic (1.30e-6)" "unprognostic (2.94e-2)" "unprognostic (2.25e-1)" "unprognostic (2.17e-1)" "unprognostic (7.48e-2)" 6.2 1.2 3.3 3.6 0.6 0.0 5.2 0.9 8.4 0.7 0.5 1.8 6.6 0.3 0.7 5.6 0.9 1.3 0.9 2.5 18.1 1.7 1.4 1.2 11.7 11.7 10.2 0.6 0.4 0.1 32.3 0.5 6.2 0.3 1.5 0.0 0.1 0.6 0.0 0.2 165.8 1.1 3.2 0.1 36.4 0.3 26.8 0.5 0.8 0.2 1.0 3.1 0.3 3.6 0.0 5.0 0.3 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.1 0.0 0.0 0.0 0.0 0.0 1.0 50.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 10.7 0.0 4.1 0.0 1.7 0.0 0.0 0.0 5.4 1.6 0.0 0.0 0.0 205.5 0.4 0.0 0.0 0.1 0.0 0.4 0.0 2.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.6 0.9 8.4 2.5 18.1 11.7 10.2 6.2 3.2 26.8 3.6 3.6 0.0 0.5 0.0 0.0 1.3 0.7 22.6 0.0 0.0 10.1 0.0 0.3 0.0 27.0 9.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.4 2.4 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 44.3 0.0 0.2 0.0 1.2 1683.2 2.0 0.3 2.6 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.5 15.0 0.0 0.0 2.5 120.8 0.0 3.5 0.0 0.0 0.0 0.9 0.8 0.1 1.2 2.3 0.1 1.3 0.0 8.1 60.4 NUDT5 "hYSAH1, YSA1H" ENSG00000165609 "Nudix hydrolase 5" Q9UKK9 10 12165330-12196144 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019827 Approved Approved Nucleoplasm,Vesicles,Centrosome NA NA 1500000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "Nucleoplasm, Centrosome" "HPA019827: AB_1854704" "unprognostic (2.08e-2)" "unprognostic (2.10e-1)" "unprognostic (1.61e-1)" "unprognostic (2.09e-1)" "unprognostic (3.77e-3)" "unprognostic (4.91e-2)" "unprognostic (2.54e-2)" "unprognostic (4.60e-2)" "unprognostic (1.32e-1)" "unprognostic (6.39e-3)" "unprognostic (2.06e-1)" "unprognostic (9.97e-2)" "prognostic unfavorable (7.14e-12)" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "unprognostic (3.12e-2)" "unprognostic (3.68e-2)" 35.1 32.4 23.0 30.6 26.4 24.1 26.7 27.5 30.5 24.6 29.5 32.0 27.5 14.3 23.7 40.7 24.6 18.4 14.9 23.4 26.0 36.3 88.8 26.0 39.3 27.3 24.9 18.0 25.9 33.1 35.5 31.1 27.4 21.0 36.0 27.4 25.1 14.0 6.2 33.2 25.4 17.6 25.0 34.2 22.6 13.1 25.4 53.5 27.8 7.6 47.4 28.9 27.8 31.8 136.4 98.0 114.6 107.1 107.5 105.6 100.8 96.9 61.5 111.9 119.1 142.5 125.9 134.2 82.4 79.2 70.0 133.1 162.0 150.6 102.1 110.8 160.8 111.9 114.3 209.3 112.0 77.1 75.2 111.7 88.4 122.3 61.7 86.3 144.9 209.4 153.5 88.9 103.2 123.8 143.5 87.0 100.4 215.0 60.1 128.0 42.4 157.2 106.0 46.1 56.6 82.3 117.4 90.8 142.2 132.0 155.9 77.9 91.6 47.0 90.6 134.3 121.9 74.3 141.6 179.3 99.7 97.3 36.0 29.6 60.8 115.2 69.9 65.7 80.4 72.7 73.9 82.6 87.6 64.6 50.4 68.4 163.8 57.4 52.2 149.2 123.4 71.6 23.0 26.4 27.5 30.5 23.4 26.0 27.3 24.9 27.4 25.0 25.4 31.8 42.1 25.6 55.1 23.2 43.8 43.0 57.8 121.2 28.5 21.1 28.6 30.7 4.5 32.9 72.3 23.9 16.7 82.6 49.8 35.0 74.3 82.2 35.3 61.1 44.4 42.6 38.3 43.5 34.6 82.9 150.6 40.3 33.1 31.9 31.7 41.4 41.7 131.8 128.7 21.9 38.2 41.2 79.3 41.8 32.2 11.7 39.4 39.7 30.2 12.2 85.0 37.4 62.8 34.2 41.2 73.8 35.2 29.0 66.1 33.7 52.6 130.6 103.9 25.5 32.9 21.2 40.1 20.2 33.6 52.4 60.5 58.1 49.7 54.4 57.4 46.9 NUS1 "C6orf68, MGC7199, NgBR, TANGO14" ENSG00000153989 "NUS1 dehydrodolichyl diphosphate synthase subunit" Q96E22 6 117675469-117710727 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Angiogenesis, Differentiation, Lipid metabolism" "Developmental protein, Receptor, Transferase" "Congenital disorder of glycosylation, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027504 Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "Plasma membrane" "HPA027504: AB_10603124" "unprognostic (1.21e-2)" "prognostic unfavorable (6.99e-4)" "unprognostic (1.09e-2)" "unprognostic (2.31e-1)" "unprognostic (1.21e-1)" "unprognostic (8.26e-3)" "unprognostic (1.42e-3)" "unprognostic (2.42e-2)" "unprognostic (8.62e-2)" "unprognostic (2.99e-1)" "unprognostic (2.62e-1)" "unprognostic (8.35e-2)" "unprognostic (1.00e-1)" "unprognostic (2.27e-1)" "unprognostic (3.22e-2)" "unprognostic (1.56e-1)" "unprognostic (7.97e-2)" 17.8 20.0 12.1 22.2 13.0 19.4 22.2 11.4 15.5 60.3 16.1 19.8 16.5 20.6 28.4 15.7 18.4 16.1 11.7 12.9 13.8 28.4 31.6 18.2 21.4 10.8 12.5 16.5 20.4 29.8 11.9 21.6 11.9 20.6 20.3 12.5 30.5 17.6 10.0 11.1 17.6 18.7 11.7 17.8 24.2 12.6 13.5 18.5 35.4 12.6 20.6 23.5 11.7 12.4 27.1 19.5 41.3 46.4 40.7 52.9 101.0 48.3 50.1 39.5 45.1 44.6 29.5 63.4 51.1 44.7 50.0 24.0 62.1 47.2 73.0 47.9 57.0 72.8 31.5 80.2 62.6 92.8 41.2 46.6 52.5 43.3 87.7 40.3 41.3 46.5 88.4 54.9 59.7 30.5 43.9 58.8 48.0 36.9 35.3 41.7 29.7 45.7 79.0 26.6 48.7 38.5 29.1 37.4 36.9 45.6 23.8 95.9 36.4 24.3 30.1 39.2 70.5 75.6 60.8 66.8 57.6 70.0 49.7 1.9 1.3 0.8 1.3 1.4 1.9 1.1 1.6 1.8 1.5 1.0 1.3 1.7 0.1 1.9 2.5 3.8 1.7 1.0 12.1 13.0 11.4 15.5 12.9 13.8 10.8 12.5 11.9 11.7 13.5 12.4 18.7 0.0 22.3 30.3 28.5 60.5 41.9 32.6 19.4 15.3 26.6 13.7 6.3 15.7 24.0 25.8 10.4 26.8 38.1 26.4 27.4 23.4 16.0 15.7 28.9 24.3 13.1 19.1 33.4 30.2 63.6 22.8 38.2 21.4 31.1 15.8 28.2 39.7 35.3 15.2 37.1 29.3 20.3 37.0 42.2 14.0 18.0 30.2 32.0 20.6 28.4 8.3 24.7 35.7 36.5 37.4 22.7 20.3 57.5 73.1 18.6 33.6 23.1 9.6 6.6 21.3 25.9 24.9 25.4 25.7 56.1 57.9 26.2 14.5 26.1 77.5 NXPE3 "FAM55C, MGC15606" ENSG00000144815 "Neurexophilin and PC-esterase domain family member 3" Q969Y0 3 101779202-101828231 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 73.2;tongue: 50.5" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 177.7;Plasma cells: 59.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 92.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036259 Uncertain Approved Nucleoplasm,Vesicles "Secreted to blood" NA NA 12000 "Cluster 20: T-cells - T-cell receptor" "Cluster 80: Striated muscle - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Nucleoplasm "HPA036259: AB_10671838" "unprognostic (3.30e-1)" "unprognostic (1.39e-1)" "unprognostic (1.53e-1)" "unprognostic (4.42e-5)" "unprognostic (4.98e-2)" "unprognostic (1.07e-1)" "unprognostic (1.81e-1)" "unprognostic (7.42e-2)" "unprognostic (1.89e-2)" "unprognostic (7.96e-2)" "unprognostic (1.57e-3)" "unprognostic (3.43e-1)" "prognostic unfavorable (7.76e-6)" "unprognostic (2.89e-1)" "unprognostic (5.23e-2)" "unprognostic (1.77e-1)" "unprognostic (8.75e-3)" 7.8 6.4 13.6 11.7 23.2 12.5 6.0 20.1 18.7 7.6 1.3 5.3 3.5 8.1 3.3 6.1 7.4 6.5 18.4 12.4 21.0 3.3 3.5 9.4 16.7 21.6 21.3 7.1 2.5 20.7 6.8 6.7 24.2 8.3 4.6 11.3 3.5 9.8 73.2 2.0 5.0 10.6 16.5 12.5 5.0 7.4 23.7 13.1 5.9 50.5 14.2 7.2 4.5 34.8 19.8 29.9 25.1 9.2 26.6 26.9 5.7 21.7 27.2 25.4 36.6 7.0 2.0 29.3 62.6 24.4 30.4 4.1 28.3 23.2 31.2 36.7 8.9 22.7 19.0 19.3 35.0 19.4 19.9 15.6 3.9 21.1 7.8 33.1 27.8 27.3 4.7 92.0 42.5 10.6 26.2 4.6 14.6 1.0 18.6 11.5 30.7 12.7 18.8 5.1 19.6 23.4 9.3 2.2 16.7 14.9 4.3 27.2 24.5 28.0 33.7 3.3 23.0 43.0 47.5 34.0 23.9 83.7 5.4 8.0 16.5 20.1 14.6 13.0 10.0 10.8 16.0 15.2 14.2 6.4 21.6 17.6 8.6 8.9 12.7 8.8 20.8 14.1 13.6 23.2 20.1 18.7 12.4 21.0 21.6 21.3 24.2 16.5 23.7 34.8 24.1 25.6 5.1 11.4 19.2 3.7 2.2 2.3 6.2 26.1 9.8 9.0 49.4 4.3 2.3 0.0 8.4 0.7 12.8 1.0 0.0 2.6 1.4 2.9 11.8 17.2 7.2 0.0 34.1 2.6 1.6 10.0 1.5 1.9 13.3 46.0 40.4 1.8 6.8 48.8 35.2 0.6 4.1 19.1 10.0 1.8 9.3 11.0 7.2 9.4 26.3 22.7 23.7 44.2 177.7 2.9 0.1 7.5 59.6 1.0 0.8 0.8 3.1 17.1 19.7 14.9 8.3 11.8 15.1 3.8 3.0 0.7 16.2 20.0 0.9 1.1 NXPH3 NPH3 ENSG00000182575 "Neurexophilin 3" O95157 17 49575871-49583827 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.4" "Cell type enhanced" "Detected in some" "Astrocytes: 14.0;Bipolar cells: 23.3;Fibroblasts: 7.6;Muller glia cells: 8.5;Peritubular cells: 14.3;Smooth muscle cells: 8.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "BEWO: 11.4;BJ: 3.2" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 4 "cerebellum: 41.1" HPA073819 Approved "Vesicles,Mitotic spindle" "Secreted in brain" Yes NA "Cluster 21: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" Vesicles "Mitotic spindle" "HPA073819: " "unprognostic (2.39e-2)" "unprognostic (4.75e-2)" "unprognostic (2.33e-2)" "unprognostic (3.34e-1)" "unprognostic (1.92e-1)" "unprognostic (3.30e-1)" "unprognostic (1.97e-1)" "unprognostic (8.01e-2)" "unprognostic (4.00e-2)" "unprognostic (1.30e-1)" "unprognostic (2.03e-2)" "unprognostic (6.33e-2)" "unprognostic (4.62e-4)" "unprognostic (2.59e-2)" "unprognostic (2.66e-1)" "unprognostic (1.06e-1)" "unprognostic (5.05e-3)" 3.9 0.9 1.8 1.0 1.8 0.0 2.9 16.4 3.5 9.0 0.7 11.0 0.4 12.0 0.6 1.5 7.0 1.7 2.9 3.5 0.5 0.4 0.1 2.7 0.5 6.3 3.8 5.2 0.6 1.3 7.5 1.3 6.4 5.9 0.3 0.6 3.1 4.7 1.2 2.3 1.7 2.5 0.1 1.0 3.4 1.6 3.9 0.3 1.4 2.0 0.3 8.9 6.9 3.0 0.0 0.0 0.1 0.0 0.0 0.2 11.4 3.2 0.4 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.6 0.1 0.4 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 16.4 3.5 3.5 0.5 6.3 3.8 6.4 0.1 3.9 3.0 0.5 0.0 1.3 14.0 0.0 0.4 0.3 0.2 0.6 23.3 0.9 0.5 1.7 1.5 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.8 1.6 0.0 0.0 2.5 0.2 3.2 7.6 0.0 0.5 0.0 0.0 6.4 0.0 0.2 0.0 1.5 0.0 0.0 0.3 1.4 0.0 4.4 0.3 1.8 0.0 4.2 8.5 0.0 2.5 0.5 0.0 0.0 14.3 0.7 0.3 0.0 0.0 0.0 1.2 0.0 0.8 8.9 0.1 1.3 0.0 1.1 0.1 0.2 0.1 0.0 0.1 NYAP1 "C7orf51, FLJ37538, KIAA1486L" ENSG00000166924 "Neuronal tyrosine phosphorylated phosphoinositide-3-kinase adaptor 1" Q6ZVC0 7 100483927-100494802 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.5;pituitary gland: 22.0" "Cell type enhanced" "Detected in some" "Astrocytes: 9.4;Bipolar cells: 6.2;Excitatory neurons: 11.1;Granulosa cells: 5.6;Horizontal cells: 13.5;Inhibitory neurons: 10.3" "Cancer enhanced" "Detected in some" "glioma: 4.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 7.8;HUVEC TERT2: 3.9;SH-SY5Y: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022251 Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Golgi apparatus" "HPA022251: AB_1848915" "unprognostic (6.59e-4)" "unprognostic (2.67e-2)" "unprognostic (1.82e-2)" "unprognostic (2.51e-4)" "unprognostic (2.89e-1)" "unprognostic (6.93e-2)" "unprognostic (1.37e-1)" "unprognostic (2.27e-1)" "unprognostic (4.86e-2)" "unprognostic (2.54e-2)" "unprognostic (2.49e-3)" "unprognostic (1.81e-1)" "unprognostic (3.25e-1)" "unprognostic (1.20e-1)" "unprognostic (3.06e-2)" "unprognostic (4.31e-1)" "unprognostic (8.65e-2)" 2.1 2.5 6.4 0.3 8.4 0.1 1.6 0.0 22.5 2.9 0.0 1.3 0.2 4.6 0.0 1.1 2.2 0.2 0.7 11.4 2.9 1.9 0.4 0.3 0.1 6.6 0.6 5.3 0.9 0.0 22.0 0.3 6.8 2.0 0.1 1.9 0.9 0.9 0.1 1.4 0.8 0.5 0.0 0.8 0.8 9.1 2.0 0.1 0.7 0.1 0.0 0.6 2.0 8.2 0.0 1.1 3.0 1.4 2.0 1.2 0.2 0.1 1.0 0.1 0.4 0.4 0.2 0.0 1.0 0.3 7.8 0.1 0.6 0.1 0.0 1.4 0.2 0.1 0.3 0.2 1.4 0.0 0.8 1.3 0.0 0.4 0.5 0.3 3.9 0.2 0.5 0.1 0.0 0.3 0.0 0.0 0.6 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.9 9.4 0.3 0.2 1.0 1.1 0.1 0.0 1.4 0.0 1.9 0.5 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 8.4 0.0 22.5 11.4 2.9 6.6 0.6 6.8 0.0 2.0 8.2 3.2 0.0 0.0 9.4 0.0 0.1 0.2 0.1 0.6 6.2 0.3 1.9 1.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.4 0.2 0.4 1.4 0.0 0.8 11.1 0.0 0.0 0.9 0.0 0.4 0.0 5.6 0.7 0.0 0.1 13.5 10.3 0.1 0.0 0.0 0.7 0.7 2.5 0.1 0.0 2.8 0.0 3.3 0.0 2.5 0.6 0.0 0.0 4.5 0.0 0.0 0.0 0.1 0.2 1.0 0.0 0.5 0.7 1.3 2.6 0.2 0.1 0.0 0.1 0.8 0.0 0.0 NYNRIN "CGIN1, FLJ11811, KIAA1305" ENSG00000205978 "NYN domain and retroviral integrase containing" Q9P2P1 14 24399003-24419283 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 18.2;Squamous epithelial cells: 18.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 14.4;HEL: 14.7;HUVEC TERT2: 35.6;RT4: 29.8;TIME: 17.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018945 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA018945: AB_1859538" "unprognostic (9.41e-3)" "unprognostic (3.96e-2)" "unprognostic (2.02e-1)" "unprognostic (4.49e-3)" "unprognostic (5.08e-2)" "unprognostic (1.14e-2)" "unprognostic (2.56e-1)" "unprognostic (2.65e-2)" "unprognostic (1.44e-3)" "unprognostic (4.21e-1)" "unprognostic (1.01e-1)" "unprognostic (4.51e-2)" "unprognostic (3.59e-2)" "unprognostic (2.39e-2)" "unprognostic (1.86e-1)" "unprognostic (3.39e-1)" "unprognostic (2.43e-1)" 8.7 3.7 4.3 3.1 3.9 0.4 6.3 16.3 4.6 16.8 5.4 7.6 4.0 11.5 28.0 11.6 16.9 8.6 7.5 3.2 6.6 6.3 4.5 8.1 1.9 5.8 5.4 35.1 3.8 5.8 5.8 12.8 6.3 7.5 5.5 1.8 7.4 14.9 3.8 13.3 5.3 10.5 3.2 4.4 6.0 5.1 7.8 4.5 7.8 4.2 2.9 9.5 14.0 2.8 0.2 0.1 4.6 0.0 6.3 13.0 0.3 2.2 2.3 1.5 1.6 3.3 14.4 0.4 0.6 8.6 0.2 0.0 7.5 0.2 1.5 0.0 0.8 14.7 2.0 0.3 4.7 0.0 0.0 13.3 0.6 1.0 0.0 2.6 35.6 0.1 2.4 0.0 0.2 0.6 0.0 0.8 2.7 1.0 0.0 1.9 0.0 0.0 0.0 29.8 0.6 10.0 0.0 1.3 0.2 11.2 2.5 2.1 17.4 0.1 8.2 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.3 3.9 16.3 4.6 3.2 6.6 5.8 5.4 6.3 3.2 7.8 2.8 15.2 3.2 1.7 4.9 0.1 4.6 3.9 9.5 15.4 0.5 1.8 3.6 3.1 8.6 15.6 9.2 0.0 1.1 1.6 2.7 0.0 4.1 0.8 1.4 10.8 15.0 5.4 3.6 1.0 3.0 1.0 10.1 10.7 1.7 0.0 12.0 18.2 2.7 10.7 0.0 3.9 9.0 4.1 9.0 1.4 0.2 2.5 1.4 3.6 3.7 0.7 5.4 0.0 0.5 0.1 4.8 5.1 0.4 1.2 1.2 1.0 0.3 10.8 0.2 0.0 1.2 7.3 0.3 1.2 18.0 3.8 1.1 0.3 1.5 8.8 4.5 OAZ1 "AZ1, AZI, MGC138338, OAZ" ENSG00000104904 "Ornithine decarboxylase antizyme 1" P54368 19 2269509-2273490 "Plasma proteins, Predicted intracellular proteins" "Polyamine biosynthesis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009291 Uncertain Approved "Vesicles,Centriolar satellite" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 43: THP-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "Centriolar satellite" "HPA009291: AB_1079519" "unprognostic (2.37e-1)" "unprognostic (9.69e-3)" "unprognostic (1.72e-1)" "unprognostic (6.04e-3)" "unprognostic (9.41e-2)" "unprognostic (1.90e-1)" "prognostic unfavorable (1.73e-4)" "unprognostic (3.75e-2)" "unprognostic (3.19e-2)" "unprognostic (6.22e-2)" "prognostic favorable (4.10e-5)" "unprognostic (3.58e-2)" "unprognostic (2.40e-1)" "unprognostic (8.37e-2)" "unprognostic (1.72e-1)" "unprognostic (2.44e-2)" "unprognostic (6.01e-2)" 201.8 252.4 114.7 170.0 125.3 330.3 177.6 107.3 189.7 143.2 111.9 204.3 161.5 134.3 91.4 167.2 151.5 109.0 289.8 132.7 121.1 203.4 172.7 194.2 244.7 119.7 122.1 139.9 209.8 46.5 173.4 134.2 117.0 150.9 77.8 36.4 226.8 89.2 525.6 177.4 197.7 85.1 116.0 294.9 188.3 67.5 120.1 68.0 144.6 123.4 138.3 170.7 152.7 113.9 577.1 117.7 88.3 152.7 181.1 287.5 228.9 400.4 275.4 197.9 269.7 169.5 181.2 389.7 210.6 187.6 78.3 163.1 87.7 120.8 129.6 523.1 303.3 301.2 108.7 267.3 184.6 425.7 456.4 192.6 207.3 74.8 112.7 177.8 227.4 141.3 297.8 439.1 226.1 210.8 357.1 442.7 291.5 83.5 210.7 291.3 176.1 519.0 184.3 164.0 207.9 220.2 264.0 236.7 464.8 70.6 198.4 890.0 293.1 140.2 173.9 610.5 427.8 423.8 188.0 468.9 636.6 660.5 217.3 1887.3 1649.6 1940.9 466.4 1685.5 469.7 962.1 506.3 502.1 1155.4 941.6 464.3 466.0 2063.4 366.1 2039.6 778.3 779.9 2803.0 114.7 125.3 107.3 189.7 132.7 121.1 119.7 122.1 117.0 116.0 120.1 113.9 492.6 365.4 510.0 54.5 1096.3 1476.0 1102.4 828.6 715.9 325.4 748.2 626.1 746.8 579.0 543.0 294.3 106.3 1065.2 1149.3 1018.3 1230.6 1043.4 95.1 452.9 335.6 591.2 613.7 1446.6 85.6 1018.2 1605.0 711.4 305.3 325.4 713.5 385.8 529.0 773.2 2248.7 222.1 78.6 816.9 547.3 2400.4 2984.5 286.7 558.6 2391.4 1136.6 60.0 2929.3 362.0 1001.1 46.3 62.2 1071.2 1388.3 477.3 1143.0 1314.8 1700.6 1540.0 553.2 285.5 460.2 487.9 821.8 251.8 256.5 751.8 1283.3 1683.5 911.1 666.9 733.6 1692.6 ODF2 "CT134, ODF84" ENSG00000136811 "Outer dense fiber of sperm tails 2" Q5BJF6 9 128455186-128501292 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "testis: 317.6" "Cell type enriched" "Detected in all" 4 "Late spermatids: 8228.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001874, HPA048841" Enhanced Supported Vesicles,Centrosome NA NA "Cluster 44: Non-specific - Transcription" "Cluster 83: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" Centrosome Vesicles "HPA001874: AB_1079522, HPA048841: AB_2680536" "unprognostic (4.54e-3)" "unprognostic (9.91e-2)" "unprognostic (4.02e-2)" "unprognostic (1.57e-3)" "unprognostic (6.11e-2)" "unprognostic (2.25e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (1.88e-1)" "unprognostic (1.79e-2)" "unprognostic (2.60e-1)" "unprognostic (6.28e-2)" "prognostic unfavorable (1.72e-4)" "unprognostic (1.93e-2)" "unprognostic (9.23e-3)" "unprognostic (1.47e-1)" "unprognostic (1.62e-1)" "unprognostic (7.65e-2)" 14.3 11.8 9.6 22.1 9.8 31.1 14.2 17.9 13.5 20.4 40.1 15.7 10.3 21.9 11.0 12.4 22.6 13.2 14.4 11.1 10.7 14.1 16.4 14.4 25.6 13.4 16.1 15.1 13.2 15.3 30.8 15.9 11.6 16.1 15.1 14.9 12.9 14.7 8.9 19.3 13.7 20.5 9.7 20.5 13.7 317.6 11.7 34.8 13.2 5.3 26.6 17.0 14.4 9.9 44.2 52.2 85.3 97.7 33.3 39.6 68.6 72.3 33.7 58.9 30.8 51.8 31.6 78.6 26.7 59.2 45.7 112.7 62.9 43.1 59.4 52.2 29.3 69.8 84.9 43.8 19.3 76.2 84.5 32.8 26.9 62.6 43.9 36.5 52.0 58.8 83.9 42.9 56.3 134.9 81.5 92.7 33.4 89.7 37.2 73.6 82.0 60.9 30.7 33.6 51.2 43.6 67.8 64.0 22.9 38.3 59.8 54.8 49.9 73.1 44.6 84.9 71.7 79.6 123.9 55.9 33.4 68.4 64.8 21.6 9.2 10.3 11.4 13.4 13.6 8.2 10.2 12.2 8.8 7.0 7.2 9.3 3.0 12.0 17.8 8.3 8.1 10.1 9.6 9.8 17.9 13.5 11.1 10.7 13.4 16.1 11.6 9.7 11.7 9.9 14.2 6.4 6.8 9.8 14.4 16.7 16.7 7.4 19.9 9.8 11.2 9.5 10.6 11.5 8.5 7.3 10.4 13.1 13.7 4.6 11.7 10.6 1914.4 39.4 16.3 18.3 3.6 29.8 18.5 9.0 16.8 14.0 10.2 13.4 19.6 10.1 8.2 9.6 12.4 8.4 16.6 10.9 12.2 10.2 14.9 8228.0 42.6 12.9 10.6 12.2 11.1 8.6 9.2 14.1 9.8 7.4 3.2 33.8 16.1 16.1 3.0 6.9 46.6 8.9 13.1 11.1 16.7 268.1 58.3 13.8 13.2 33.2 16.8 11.4 7.6 12.9 OIP5 "CT86, hMIS18beta, MIS18B" ENSG00000104147 "Opa interacting protein 5" O43482 15 41309273-41332591 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.3;skeletal muscle: 10.3;testis: 20.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 45.9;Extravillous trophoblasts: 24.0;Spermatocytes: 110.6;Spermatogonia: 56.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA052271, HPA059602" Enhanced Supported "Nuclear speckles,Vesicles" NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear speckles" Vesicles "HPA052271: AB_2681780, HPA059602: AB_2684079" "unprognostic (5.17e-2)" "unprognostic (7.26e-2)" "unprognostic (3.07e-1)" "unprognostic (1.59e-2)" "unprognostic (6.94e-2)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.79e-4)" "prognostic unfavorable (2.26e-4)" "unprognostic (2.71e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (9.34e-5)" "unprognostic (5.51e-2)" "unprognostic (0.00e+0)" "unprognostic (3.84e-2)" "unprognostic (2.02e-1)" "unprognostic (5.75e-2)" "unprognostic (2.86e-2)" 0.6 1.7 0.1 3.3 0.2 10.3 1.2 1.2 0.4 0.9 0.2 4.1 3.5 0.8 0.3 3.8 0.4 0.6 1.5 0.2 0.2 0.3 1.2 0.5 5.8 0.2 0.4 1.5 0.3 0.1 0.1 2.3 0.4 0.5 3.9 0.7 0.8 0.6 10.3 3.3 3.9 1.1 0.1 1.7 1.5 20.9 0.2 9.1 0.4 0.8 5.2 0.7 1.3 0.5 33.7 17.8 34.3 24.9 1.7 2.1 32.4 20.0 9.3 24.5 26.1 31.8 16.2 19.8 17.0 7.7 37.8 51.0 35.7 16.1 19.2 42.4 40.1 42.4 49.8 33.6 0.4 46.5 22.1 0.7 3.2 13.8 14.5 5.2 21.1 40.8 59.4 37.3 16.5 16.3 27.1 34.8 30.9 50.4 37.9 32.9 28.4 30.5 11.1 15.4 53.7 17.5 33.7 34.3 9.6 13.7 33.7 26.3 10.0 24.5 37.3 24.6 36.6 17.0 83.2 71.1 7.1 56.5 35.9 0.0 0.4 0.5 0.2 0.7 0.8 1.0 0.7 0.8 0.7 1.2 1.3 0.8 0.0 1.2 0.4 4.1 3.1 0.8 0.1 0.2 1.2 0.4 0.2 0.2 0.2 0.4 0.4 0.1 0.2 0.5 0.2 0.0 0.5 1.0 2.7 4.1 0.9 3.6 1.2 0.0 1.1 2.2 0.2 0.0 1.8 0.0 0.0 15.0 1.7 2.3 0.0 0.4 12.0 1.9 0.6 0.9 0.0 45.9 2.2 0.4 24.0 1.7 5.1 1.1 1.3 5.2 0.0 0.8 7.5 0.0 2.1 3.0 8.2 2.2 1.8 10.8 0.9 1.2 0.0 0.0 0.6 1.1 2.1 1.5 2.5 0.2 0.5 1.2 10.9 0.4 0.9 0.3 0.0 0.3 6.6 1.0 1.1 110.6 56.8 8.3 2.4 3.8 1.2 2.1 7.6 0.9 OLFM3 NOE3 ENSG00000118733 "Olfactomedin 3" Q96PB7 1 101802560-101996926 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 12.0;retina: 7.4" "Group enriched" "Detected in some" 17 "Excitatory neurons: 653.3;Inhibitory neurons: 174.6" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "AF22: 5.7;HAP1: 3.9;HEL: 3.6;SCLC-21H: 2.2;SH-SY5Y: 2.2" "Region enhanced" "Detected in all" "cerebellum: 177.3" "Low region specificity" "Detected in all" HPA050297 Uncertain Vesicles "Secreted in brain" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA050297: " "unprognostic (4.19e-1)" "unprognostic (4.19e-4)" "unprognostic (1.26e-1)" "unprognostic (4.61e-2)" "unprognostic (2.93e-1)" "unprognostic (1.47e-2)" "unprognostic (3.58e-4)" "unprognostic (2.48e-1)" "unprognostic (5.68e-2)" 0.0 1.3 2.9 0.3 5.0 0.0 0.0 6.9 12.0 0.0 0.0 0.6 0.2 0.1 0.2 0.0 0.0 0.0 0.0 6.4 3.9 0.4 0.0 0.0 0.0 1.2 1.9 0.0 0.0 0.0 1.2 0.0 1.2 0.0 0.5 7.4 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.1 0.2 0.1 3.7 0.0 0.3 0.0 0.0 0.0 0.0 4.6 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.0 0.0 2.2 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 5.0 6.9 12.0 6.4 3.9 1.2 1.9 1.2 0.0 3.7 4.6 0.1 0.0 0.0 10.7 0.0 0.0 0.1 0.0 0.0 23.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 653.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 174.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 5.6 0.0 0.7 0.0 8.5 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 6.5 0.0 0.0 OLFML3 "HNOEL-iso, OLF44" ENSG00000116774 "Olfactomedin like 3" Q9NRN5 1 113979391-114035572 "Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 136.6;Fibroblasts: 246.9;Leydig cells: 73.3;Theca cells: 126.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "myeloid DC: 2.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.1" "Cell line enhanced" "Detected in many" "ASC diff: 577.3;ASC TERT1: 312.6;BJ hTERT+: 374.8;HSkMC: 581.6;LHCN-M2: 602.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027991 Supported Vesicles "Secreted to extracellular matrix" NA NA 3000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA027991: AB_2732440" "unprognostic (1.04e-1)" "unprognostic (8.06e-2)" "unprognostic (1.87e-1)" "unprognostic (1.50e-2)" "unprognostic (1.41e-1)" "unprognostic (1.50e-1)" "unprognostic (2.02e-1)" "unprognostic (3.72e-1)" "unprognostic (1.67e-1)" "unprognostic (3.04e-2)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (3.45e-5)" "unprognostic (6.80e-3)" "unprognostic (1.88e-1)" "unprognostic (2.61e-1)" "unprognostic (4.41e-3)" 85.6 42.6 5.7 24.9 7.4 0.9 89.7 7.2 12.4 170.6 8.2 71.9 15.1 124.7 42.6 26.6 96.3 95.0 56.6 5.4 6.7 34.1 36.3 55.4 12.0 9.8 7.7 177.4 35.2 9.9 17.9 111.8 8.6 42.9 34.5 0.2 16.7 73.8 10.3 37.6 32.3 94.6 9.2 9.9 48.4 9.3 9.7 8.9 21.8 38.2 14.9 71.1 98.8 11.2 0.0 19.7 9.7 0.1 577.3 312.6 0.6 77.1 374.8 26.5 85.3 25.2 0.2 0.0 4.1 222.4 0.2 0.0 3.2 0.3 4.0 0.0 0.0 0.0 0.1 19.3 149.6 0.2 0.0 581.6 0.0 37.2 0.5 10.7 2.1 0.0 0.0 0.1 602.3 0.3 0.2 0.4 45.8 0.0 0.7 0.1 142.6 0.3 0.0 0.0 0.3 5.4 0.1 0.2 10.5 143.3 224.6 0.9 1.8 14.9 27.6 5.9 0.0 0.2 0.1 0.0 7.3 0.0 94.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.7 7.4 7.2 12.4 5.4 6.7 9.8 7.7 8.6 9.2 9.7 11.2 13.6 0.0 3.7 0.0 0.4 13.0 0.2 0.0 0.6 0.0 2.1 2.9 1.4 4.3 0.8 1.8 0.0 6.8 1.1 0.2 0.0 0.8 2.9 6.2 136.6 9.5 6.0 0.0 0.0 0.0 4.9 246.9 5.6 3.5 1.3 0.3 45.7 0.5 33.3 0.0 0.0 0.6 0.0 5.9 22.7 1.7 73.3 15.5 12.4 16.9 0.6 0.0 0.0 0.0 0.1 0.3 0.1 33.1 0.2 0.7 0.0 0.5 0.0 0.1 0.0 44.8 28.0 0.3 0.4 1.2 11.5 12.4 2.6 126.1 0.2 0.2 OLR1 "CLEC8A, LOX-1, SCARE1" ENSG00000173391 "Oxidized low density lipoprotein receptor 1" P78380 12 10158301-10172138 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity, Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 52.6;lung: 100.2;placenta: 114.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 399.0;Hofbauer cells: 202.1;Macrophages: 202.6;Syncytiotrophoblasts: 463.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CACO-2: 125.4;HaCaT: 64.9;HHSteC: 125.1;hTCEpi: 58.4;SiHa: 248.8;SK-BR-3: 96.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050798 Approved "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 1060000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Plasma membrane" Vesicles "HPA050798: AB_2756318" "unprognostic (2.30e-1)" "unprognostic (3.16e-2)" "unprognostic (1.58e-2)" "unprognostic (1.32e-1)" "unprognostic (7.81e-2)" "prognostic unfavorable (8.24e-5)" "unprognostic (6.34e-2)" "unprognostic (6.07e-3)" "unprognostic (5.40e-2)" "unprognostic (2.64e-1)" "unprognostic (1.97e-2)" "unprognostic (3.51e-1)" "unprognostic (1.08e-1)" "unprognostic (4.94e-3)" "unprognostic (3.47e-2)" "unprognostic (1.48e-2)" "unprognostic (1.42e-1)" 3.0 3.3 9.0 29.1 13.1 23.8 3.6 18.9 16.9 3.3 8.8 0.7 1.3 1.6 1.3 0.5 2.1 7.4 1.5 9.4 13.3 8.2 3.1 100.2 0.7 25.5 15.6 0.3 2.2 4.1 2.7 114.5 26.0 2.3 1.0 5.1 3.8 1.0 0.5 0.6 1.2 2.1 27.6 0.8 2.3 4.7 24.0 2.8 2.5 0.0 0.8 6.0 0.3 52.6 7.3 0.5 0.1 0.3 0.3 0.0 16.8 12.1 2.2 7.3 2.6 125.4 0.1 1.6 0.0 15.8 0.5 64.9 0.0 0.7 4.9 0.0 0.0 0.0 6.1 0.0 125.1 0.1 0.3 1.0 58.4 0.3 0.0 0.0 0.3 0.1 0.1 0.7 0.0 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.2 0.3 0.2 13.3 0.4 0.2 248.8 96.9 0.0 17.4 27.1 0.0 0.1 0.2 1.4 0.0 0.0 0.4 0.3 0.4 0.1 0.1 0.1 0.6 0.6 1.3 0.1 0.1 0.1 0.1 0.1 0.0 2.8 0.2 0.1 0.1 1.4 0.1 0.1 0.3 0.1 0.6 9.0 13.1 18.9 16.9 9.4 13.3 25.5 15.6 26.0 27.6 24.0 52.6 1.9 28.9 27.4 0.0 4.0 1.5 0.4 0.5 0.0 0.4 1.1 4.6 0.1 1.5 4.4 0.0 0.0 399.0 0.3 0.0 0.0 0.1 13.4 0.1 0.0 10.8 0.0 0.4 2.3 0.0 14.6 10.9 0.5 0.1 15.2 0.0 0.0 0.5 202.1 0.0 0.2 0.0 0.0 18.9 79.5 11.6 0.3 202.6 0.0 40.3 21.3 0.1 0.0 0.5 0.5 0.0 0.0 0.0 1.3 0.0 0.0 0.2 6.6 0.2 0.0 0.2 0.4 0.1 0.2 0.8 0.6 463.1 1.6 0.1 0.0 0.3 ORM1 ENSG00000229314 "Orosomucoid 1" P02763 9 114323056-114326475 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Acute phase, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 193 "liver: 42973.6" "Cell type enriched" "Detected in some" 46 "Hepatocytes: 58657.7" "Cancer enriched" "Detected in many" 16 "liver cancer: 2506.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 47 "neutrophil: 193.9" "Lineage enriched" "Detected in many" 47 "granulocytes: 193.9" "Cell line enriched" "Detected in some" 12 "Hep G2: 1182.7" "CAB006265, HPA046438, HPA047725, HPA057726" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 945000000000 61000000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "Golgi apparatus" "CAB006265: AB_425575, HPA046438: AB_2679666, HPA047725: AB_2680133, HPA057726: AB_2683512" "unprognostic (3.85e-1)" "unprognostic (2.12e-1)" "unprognostic (1.09e-2)" "unprognostic (2.16e-2)" "unprognostic (3.22e-2)" "unprognostic (1.47e-1)" "unprognostic (2.29e-1)" "unprognostic (2.26e-1)" "unprognostic (1.16e-1)" "unprognostic (4.85e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (2.35e-4)" "unprognostic (2.10e-1)" "unprognostic (4.38e-2)" "unprognostic (9.32e-3)" "unprognostic (4.51e-2)" 13.4 10.3 0.1 12.7 0.3 223.1 6.6 0.0 0.4 2.7 0.2 1.5 0.1 2.7 0.3 1.9 1.9 1.0 3.4 0.2 0.2 4.9 42973.6 24.4 0.7 0.4 0.2 1.6 8.1 0.0 1.4 1.3 0.1 57.6 0.0 1.1 1.4 0.0 2.0 1.7 2.3 0.3 0.2 51.3 19.2 2.7 0.1 1.2 2.8 0.3 0.1 1.6 2.2 0.2 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 2.1 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 3.4 0.6 1182.7 0.1 5.3 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.5 0.0 0.2 0.0 0.2 1.0 0.1 0.0 0.7 7.1 0.0 0.0 0.4 0.0 0.0 5.7 5.5 0.0 0.0 0.4 102.0 1.2 0.0 0.5 0.0 0.0 1.2 0.6 3.5 0.0 4.3 0.1 0.0 4.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 193.9 0.0 1.0 0.0 0.0 1.8 0.1 0.3 0.0 0.4 0.2 0.2 0.4 0.2 0.1 0.2 0.1 0.2 0.0 3.2 18.1 0.0 81.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1166.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 23.6 0.0 1.3 0.2 34.4 0.0 890.4 0.0 4.9 0.3 0.2 0.0 2.5 0.0 0.0 930.9 58657.7 0.1 0.0 0.0 0.0 0.0 1260.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.0 29.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 78.6 0.0 0.0 0.3 ORM2 "AGP-B, AGP-B', AGP2" ENSG00000228278 "Orosomucoid 2" P19652 9 114329869-114333251 "Plasma proteins, Predicted secreted proteins" "Acute phase, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 327 "liver: 8873.2" "Cell type enriched" "Detected in some" 41 "Hepatocytes: 10792.5" "Cancer enriched" "Detected in many" 34 "liver cancer: 873.1" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 40 "neutrophil: 12.0" "Lineage enriched" "Detected in single" 40 "granulocytes: 12.0" "Cell line enriched" "Detected in some" 232 "Hep G2: 831.1" "HPA046438, HPA047725, HPA057726" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 422000000 41000000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Golgi apparatus" "HPA046438: AB_2679666, HPA047725: AB_2680133, HPA057726: AB_2683512" "unprognostic (6.77e-2)" "unprognostic (8.00e-2)" "unprognostic (1.19e-1)" "unprognostic (4.44e-3)" "unprognostic (1.18e-1)" "unprognostic (5.61e-2)" "unprognostic (5.66e-2)" "unprognostic (9.70e-2)" "unprognostic (3.05e-1)" "unprognostic (1.48e-1)" "unprognostic (1.99e-2)" "unprognostic (5.76e-2)" "prognostic unfavorable (1.23e-9)" "unprognostic (3.23e-1)" "unprognostic (6.80e-2)" "unprognostic (7.62e-2)" "unprognostic (9.15e-4)" 4.0 4.0 0.2 3.2 0.4 27.1 3.0 0.0 0.2 1.3 0.2 0.3 0.2 2.1 0.1 0.4 0.4 0.6 0.8 0.1 0.1 1.7 8873.2 5.8 1.1 0.2 0.3 0.3 2.1 0.0 0.2 0.2 0.1 23.6 0.1 3.6 0.3 0.0 0.4 0.4 0.4 0.1 0.2 7.3 21.9 1.4 0.1 0.5 0.3 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.2 0.0 831.1 0.0 3.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.2 0.0 0.0 0.1 1.1 0.4 2.5 0.0 0.3 1.9 0.1 0.0 0.3 0.1 0.0 2.6 2.0 0.2 0.1 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.7 0.6 2.2 0.0 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.0 0.0 0.1 0.0 0.0 0.1 0.2 0.4 0.0 0.2 0.1 0.1 0.2 0.3 0.1 0.2 0.1 0.2 0.0 0.0 10.5 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 263.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 6.6 1.1 0.1 7.0 0.0 141.7 0.0 6.0 0.0 0.0 15.8 1.3 0.0 0.0 162.8 10792.5 0.0 0.0 0.0 0.0 0.0 236.1 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 0.0 0.0 0.2 OSBPL5 "KIAA1534, OBPH1, ORP5" ENSG00000021762 "Oxysterol binding protein like 5" Q9H0X9 11 3087107-3166739 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 34.6;Horizontal cells: 62.2;NK-cells: 56.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 3.6;gdT-cell: 9.0;intermediate monocyte: 4.7;memory CD8 T-cell: 3.3;myeloid DC: 3.0;naive CD8 T-cell: 3.4;NK-cell: 11.0;non-classical monocyte: 11.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NB-4: 75.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038335, HPA038712, HPA058727" Approved Enhanced Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA038335: AB_2675963, HPA038712: AB_10675949, HPA058727: AB_2683799" "unprognostic (6.02e-2)" "unprognostic (1.16e-1)" "unprognostic (1.68e-1)" "unprognostic (3.69e-2)" "unprognostic (8.22e-3)" "unprognostic (1.71e-1)" "unprognostic (1.25e-1)" "unprognostic (4.03e-3)" "unprognostic (1.29e-1)" "unprognostic (3.49e-3)" "unprognostic (2.16e-3)" "unprognostic (9.44e-2)" "unprognostic (2.78e-2)" "unprognostic (1.22e-1)" "unprognostic (6.50e-2)" "unprognostic (7.67e-2)" "unprognostic (2.60e-1)" 22.0 8.0 7.1 7.2 7.7 13.6 19.2 7.8 11.5 42.2 2.1 28.2 5.9 26.6 2.9 12.5 22.3 5.0 14.9 5.2 6.4 13.5 3.1 17.5 2.4 50.3 13.3 14.5 10.4 2.3 10.3 5.0 56.0 25.6 3.2 1.8 16.4 9.9 9.9 25.9 16.6 7.6 5.4 24.9 15.5 3.3 19.8 22.0 14.9 5.9 1.4 24.6 28.3 10.5 3.7 5.6 6.6 7.6 18.9 8.8 0.1 17.9 8.8 7.1 5.0 0.0 10.4 0.0 5.3 10.1 4.9 13.3 1.3 5.0 1.1 3.5 6.0 15.1 19.2 0.0 15.9 13.6 2.3 13.9 5.7 2.5 2.6 5.2 4.8 26.7 5.5 0.0 3.5 10.3 30.7 75.5 4.8 2.4 11.5 15.9 9.0 2.2 3.0 3.3 10.8 1.3 7.6 26.1 7.0 3.7 10.8 35.9 16.4 8.8 12.1 21.2 3.1 3.8 0.0 0.5 9.5 25.3 11.5 0.2 3.6 1.2 9.0 4.7 1.2 0.0 0.9 3.3 3.0 0.0 0.6 3.4 0.4 11.0 11.5 1.3 0.1 5.2 7.1 7.7 7.8 11.5 5.2 6.4 50.3 13.3 56.0 5.4 19.8 10.5 19.5 0.0 5.5 8.1 0.5 4.8 2.6 4.2 5.2 11.5 7.7 5.2 6.9 2.8 4.8 3.7 8.4 0.4 34.6 8.3 1.9 3.0 0.1 2.2 22.1 12.1 0.0 5.7 25.6 2.0 0.6 12.3 5.1 2.5 1.3 3.5 3.9 0.5 1.7 62.2 20.6 8.0 2.0 8.7 3.1 1.2 9.0 3.9 3.6 17.8 2.3 4.1 56.7 20.1 28.2 2.2 8.5 17.0 4.9 3.2 6.1 3.2 5.5 1.2 13.1 7.4 11.4 0.1 0.6 3.8 6.8 0.0 9.1 2.5 8.2 2.5 OSBPL8 "MST120, MSTP120, ORP8, OSBP10" ENSG00000091039 "Oxysterol binding protein like 8" Q9BZF1 12 76351797-76559809 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001309 Uncertain Approved Vesicles,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 36: HEL - Hemostasis" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Cytosol" "HPA001309: AB_1079530" "unprognostic (2.55e-1)" "unprognostic (2.68e-2)" "unprognostic (2.77e-1)" "unprognostic (1.70e-1)" "unprognostic (5.20e-2)" "unprognostic (1.23e-1)" "unprognostic (6.55e-3)" "unprognostic (2.84e-1)" "unprognostic (7.88e-2)" "unprognostic (1.61e-2)" "prognostic unfavorable (9.79e-4)" "unprognostic (6.58e-2)" "unprognostic (1.13e-2)" "unprognostic (5.63e-3)" "unprognostic (2.96e-1)" "unprognostic (1.16e-1)" "unprognostic (3.19e-3)" 24.2 13.5 18.1 24.3 43.3 32.5 21.1 9.7 22.5 22.6 12.3 11.2 9.3 22.3 7.7 24.4 10.5 18.4 14.0 15.3 13.7 36.4 19.2 19.6 30.9 11.7 13.4 17.4 14.0 13.0 5.6 18.2 14.0 14.9 11.7 14.2 13.5 12.7 10.7 28.7 13.0 18.9 9.1 26.7 16.0 16.6 13.1 33.7 14.3 11.5 32.0 19.1 10.2 16.6 36.5 22.8 49.7 35.5 67.5 94.8 31.6 54.7 76.3 34.2 31.1 33.2 14.6 50.8 30.4 65.3 21.5 14.9 37.2 31.6 51.3 43.6 33.3 136.0 21.0 19.8 41.7 87.2 53.1 50.4 58.7 51.2 63.3 61.8 30.0 29.1 95.0 22.7 57.3 25.0 58.8 41.4 24.3 13.2 22.6 30.4 67.7 29.3 26.4 30.3 27.2 28.4 46.7 16.6 34.0 38.9 13.0 52.4 70.6 55.0 27.5 57.5 29.7 22.7 38.4 54.6 21.0 47.9 32.8 134.8 50.8 74.1 29.2 37.4 27.9 45.3 31.2 24.6 46.9 40.8 27.9 23.2 195.7 36.0 44.5 54.9 41.1 31.8 18.1 43.3 9.7 22.5 15.3 13.7 11.7 13.4 14.0 9.1 13.1 16.6 63.5 57.7 58.3 54.5 87.8 116.2 65.7 39.6 114.9 49.7 68.4 55.5 42.5 25.8 36.1 51.5 89.6 34.8 111.3 13.6 60.7 53.9 47.4 29.0 102.6 68.7 9.5 63.5 246.3 55.2 28.7 98.0 28.5 44.1 254.8 36.3 52.1 45.9 77.1 42.1 248.6 25.8 40.7 98.0 127.0 22.1 65.9 142.0 35.6 79.6 149.3 50.2 125.7 113.6 92.9 104.0 28.3 82.8 56.8 54.6 23.9 180.2 37.4 37.3 46.0 79.3 83.1 66.2 129.9 89.9 124.5 48.2 105.3 58.4 20.0 62.4 OSBPL9 ENSG00000117859 "Oxysterol binding protein like 9" Q96SU4 1 51577179-51798427 "Plasma proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 216.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027378, HPA027397" Supported Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus" Vesicles "HPA027378: AB_1854816, HPA027397: AB_1854817" "unprognostic (5.99e-2)" "unprognostic (1.93e-2)" "unprognostic (1.22e-2)" "unprognostic (2.43e-3)" "unprognostic (3.11e-1)" "unprognostic (6.72e-2)" "unprognostic (2.85e-2)" "unprognostic (2.47e-1)" "unprognostic (4.17e-3)" "unprognostic (1.58e-1)" "unprognostic (8.36e-3)" "unprognostic (8.61e-2)" "unprognostic (3.64e-2)" "unprognostic (7.53e-3)" "unprognostic (2.55e-1)" "unprognostic (4.95e-2)" "unprognostic (3.37e-1)" 27.5 38.1 17.9 18.1 23.8 30.1 32.6 26.3 23.5 25.5 28.3 20.8 17.4 31.1 31.0 17.7 23.3 17.6 37.0 17.6 23.9 42.8 60.8 27.5 25.9 25.0 21.8 30.5 33.3 60.0 21.1 21.8 26.6 27.8 19.1 53.5 22.0 22.4 70.0 19.6 21.7 24.2 23.0 27.2 34.3 28.4 22.2 21.8 24.7 35.2 33.0 23.7 24.7 32.2 66.3 31.7 69.0 11.2 38.1 17.9 90.7 30.1 50.8 54.9 60.0 53.0 46.6 105.8 54.4 34.1 120.9 26.9 59.2 57.4 76.9 71.9 41.9 77.4 62.7 104.7 36.9 81.7 35.5 44.7 55.0 56.8 31.4 66.8 68.9 52.1 154.4 31.1 26.7 45.4 20.3 92.5 97.0 26.8 15.1 58.2 102.8 110.5 74.0 47.4 31.8 45.2 22.4 79.6 93.7 154.7 38.0 82.8 22.9 11.6 51.2 17.2 58.1 80.2 52.5 120.4 39.3 32.8 23.0 52.7 12.2 30.5 20.1 9.9 28.9 32.6 19.7 20.8 25.0 23.9 21.0 22.2 16.9 16.3 9.4 23.2 20.5 16.4 17.9 23.8 26.3 23.5 17.6 23.9 25.0 21.8 26.6 23.0 22.2 32.2 32.5 80.1 56.8 75.4 39.2 17.7 33.8 25.7 34.1 102.0 34.2 33.0 47.9 38.6 50.5 46.0 41.7 89.2 30.4 20.5 125.2 47.6 40.7 36.3 46.3 30.1 29.8 35.7 64.8 47.8 50.2 48.6 54.0 52.9 33.6 75.7 18.2 61.7 40.1 26.9 113.0 18.3 38.7 22.7 16.0 38.3 62.4 25.3 65.8 63.7 50.1 43.8 29.9 62.8 216.4 41.9 14.3 50.0 81.4 38.5 26.4 59.7 32.1 35.3 46.0 36.9 62.9 32.3 18.9 26.9 18.9 75.5 32.0 52.2 21.2 27.4 OSTM1 "GL, HSPC019" ENSG00000081087 "Osteoclastogenesis associated transmembrane protein 1" Q86WC4 6 108041409-108165854 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Osteopetrosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Melanocytes: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010851 Uncertain Approved Nucleoplasm,Vesicles,Cytosol No No 210000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 4: Macrophages - Innate immune response" Cytosol "Nucleoplasm, Vesicles" "HPA010851: AB_1079533" "prognostic unfavorable (4.36e-4)" "unprognostic (4.03e-2)" "unprognostic (2.81e-1)" "unprognostic (1.11e-1)" "unprognostic (1.16e-1)" "unprognostic (1.72e-3)" "prognostic unfavorable (4.26e-4)" "unprognostic (9.40e-2)" "unprognostic (2.56e-1)" "unprognostic (2.25e-1)" "unprognostic (4.06e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (1.34e-6)" "prognostic unfavorable (1.20e-4)" "unprognostic (2.32e-2)" "unprognostic (1.40e-1)" "unprognostic (1.77e-1)" 26.1 19.1 4.7 17.9 5.2 5.7 9.8 5.1 5.8 10.4 33.1 12.2 7.9 13.7 9.0 12.7 9.5 12.5 19.2 5.3 9.2 15.6 13.1 16.2 14.7 6.0 7.6 7.5 5.8 15.3 8.3 14.1 7.9 13.8 11.1 17.6 8.9 16.7 11.8 9.8 9.0 23.3 5.3 18.3 8.5 10.1 7.4 13.7 10.7 11.5 13.5 16.9 7.0 8.3 6.0 17.2 20.1 29.4 59.0 19.0 28.6 42.8 42.7 30.7 50.4 10.0 9.8 13.7 34.4 30.0 82.5 11.1 20.2 14.6 47.0 31.6 15.7 28.9 10.9 12.8 45.6 32.1 64.6 28.1 35.7 37.7 30.0 28.2 15.8 15.2 23.3 48.7 50.3 8.4 7.1 7.3 8.0 7.1 13.0 11.4 29.1 7.5 22.0 15.7 2.2 11.8 34.7 8.7 79.9 26.6 10.0 45.8 19.3 26.7 9.8 59.7 61.4 18.6 34.4 11.9 78.9 21.3 60.3 31.4 20.2 22.8 20.3 29.4 21.5 14.7 16.9 22.3 17.8 8.6 15.6 19.8 29.8 22.0 43.5 12.9 22.6 27.0 4.7 5.2 5.1 5.8 5.3 9.2 6.0 7.6 7.9 5.3 7.4 8.3 28.5 9.6 19.0 26.4 26.0 46.7 19.8 11.7 21.6 28.3 10.0 7.0 24.8 12.8 9.4 12.9 10.4 21.7 32.3 21.9 1.9 12.4 12.0 7.5 15.7 20.7 4.2 4.6 36.6 22.9 33.9 24.4 15.8 9.6 24.1 6.9 26.7 13.2 52.8 28.6 40.1 5.8 6.1 46.5 29.5 5.4 14.3 43.1 151.2 20.6 25.6 23.7 40.2 21.1 36.6 16.8 17.0 28.6 25.0 17.9 7.6 25.5 9.8 17.5 26.3 18.5 29.6 28.0 18.7 12.4 31.1 61.2 29.5 23.7 3.3 16.0 OTUD6A "DUBA2, FLJ25831, HSHIN6" ENSG00000189401 "OTU deubiquitinase 6A" Q7L8S5 X 70062457-70064179 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "testis: 4.8" "Group enriched" "Detected in some" 17 "Spermatocytes: 64.1;Spermatogonia: 25.1" "Cancer enriched" "Detected in single" 57 "testis cancer: 2.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA053304 Enhanced Approved Vesicles,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol Vesicles "HPA053304: AB_2682107" "unprognostic (1.58e-1)" 0.0 0.0 0.2 0.0 0.2 0.5 0.0 0.5 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 4.8 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.6 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.5 0.3 0.2 0.2 0.2 0.2 0.2 0.1 0.2 0.4 0.1 0.0 0.5 0.0 0.0 0.4 0.1 0.0 0.0 0.5 0.4 0.4 1.2 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.6 0.4 0.3 0.6 0.0 0.0 0.1 0.0 0.1 2.6 0.0 0.3 1.3 0.7 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.6 0.9 0.7 0.3 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.5 0.1 0.3 0.0 0.3 0.0 1.8 0.0 0.4 0.4 64.1 25.1 0.0 0.6 0.3 1.0 0.2 0.0 0.2 OTX2 ENSG00000165588 "Orthodenticle homeobox 2" P32243 14 56799905-56816693 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "choroid plexus: 108.8;retina: 279.9" "Group enriched" "Detected in some" 11 "Bipolar cells: 170.6;Cone photoreceptor cells: 168.9;Rod photoreceptor cells: 202.5" "Cancer enriched" "Detected in single" 27 "testis cancer: 11.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 249.6;hTERT-RPE1: 57.0;NTERA-2: 199.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA000633, HPA001123" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm Vesicles "HPA000633: AB_1079538, HPA001123: " "unprognostic (3.82e-1)" "unprognostic (2.56e-2)" "unprognostic (9.28e-2)" 0.0 0.0 4.1 0.0 1.3 0.0 0.0 8.5 0.5 0.0 108.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.9 2.6 0.0 0.0 0.0 0.0 0.2 8.7 0.0 0.0 0.0 2.5 0.0 2.0 0.0 0.0 279.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 12.8 0.0 0.0 0.8 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 249.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 57.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 199.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 1.3 8.5 0.5 5.9 2.6 0.2 8.7 2.0 0.1 12.8 5.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 170.6 0.0 0.0 0.3 0.0 0.0 0.0 168.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 202.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OVGP1 "CHIT5, MUC9" ENSG00000085465 "Oviductal glycoprotein 1" Q12889 1 111414319-111427735 "Plasma proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 134 "fallopian tube: 2071.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 9.7;Excitatory neurons: 10.4;Glandular and luminal cells: 12.0;Inhibitory neurons: 8.5;Syncytiotrophoblasts: 17.4" "Group enriched" "Detected in many" 13 "endometrial cancer: 58.7;ovarian cancer: 27.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 4.9;OE19: 6.4;SK-BR-3: 5.0" "Region enhanced" "Detected in many" "cerebellum: 5.9" "Not detected" "Not detected" "HPA031666, HPA062205" Enhanced Supported Vesicles,Microtubules "Secreted in female reproductive system" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" Vesicles Microtubules "HPA031666: , HPA062205: AB_2684710" "unprognostic (1.52e-1)" "unprognostic (2.06e-2)" "unprognostic (3.35e-2)" "prognostic favorable (1.36e-4)" "unprognostic (8.39e-2)" "unprognostic (3.58e-2)" "unprognostic (2.33e-2)" "unprognostic (3.34e-2)" "unprognostic (5.44e-2)" "unprognostic (3.82e-2)" "unprognostic (7.68e-3)" "unprognostic (2.58e-1)" "unprognostic (5.35e-3)" "unprognostic (2.39e-1)" "unprognostic (1.38e-1)" "unprognostic (3.86e-3)" "prognostic favorable (3.93e-5)" 4.1 1.6 7.6 1.1 7.8 1.9 3.5 8.0 10.6 3.8 5.8 3.4 1.1 15.4 5.1 3.0 2071.7 1.1 2.3 7.7 7.0 5.0 8.0 3.9 2.2 7.3 6.9 6.7 1.5 6.8 2.4 2.0 7.2 5.5 2.2 4.3 4.2 1.5 2.6 7.6 5.2 1.4 6.5 4.6 2.8 9.2 6.9 1.2 2.4 1.0 2.0 4.6 3.8 8.2 0.4 0.4 0.9 0.5 1.8 2.0 1.7 0.2 1.4 0.3 0.7 0.6 0.0 0.8 1.7 0.6 0.0 0.5 0.3 0.3 0.5 2.0 4.9 0.3 0.8 2.4 0.6 0.9 2.2 1.8 2.9 0.0 1.0 1.4 0.4 3.2 0.3 1.5 0.1 0.5 0.6 1.2 0.2 6.4 1.7 0.6 0.2 0.7 1.4 3.7 0.6 0.6 0.1 5.0 0.7 2.4 0.3 0.8 0.8 0.1 0.2 2.5 0.7 1.8 0.5 0.4 0.2 1.6 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 7.6 7.8 8.0 10.6 7.7 7.0 7.3 6.9 7.2 6.5 6.9 8.2 1.2 0.0 1.1 3.3 0.6 3.1 1.1 0.3 0.0 2.1 1.7 1.9 0.6 0.0 0.5 0.0 0.0 5.6 0.2 1.1 1.9 0.2 4.0 9.7 0.7 1.6 0.0 0.0 10.4 0.0 2.6 0.6 0.0 12.0 0.0 1.0 1.4 2.9 0.6 0.0 8.5 1.5 2.0 0.6 1.4 6.1 1.5 0.5 0.0 3.7 0.0 0.4 0.0 1.5 2.4 0.2 0.5 1.9 0.1 1.6 0.6 2.8 1.3 0.6 0.0 0.7 1.1 3.8 0.7 1.0 3.1 17.4 0.8 0.2 1.6 1.6 OXLD1 "C17orf90, MGC104712" ENSG00000204237 "Oxidoreductase like domain containing 1" Q5BKU9 17 81665036-81666635 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 56.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056878, HPA057019" Uncertain Approved Vesicles,Cytosol NA NA 12000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Vesicles, Cytosol" "HPA056878: AB_2683265, HPA057019: AB_2683310" "unprognostic (1.08e-1)" "prognostic favorable (2.91e-4)" "unprognostic (1.37e-1)" "unprognostic (1.38e-1)" "unprognostic (9.03e-2)" "unprognostic (3.79e-2)" "unprognostic (1.07e-2)" "unprognostic (1.92e-2)" "unprognostic (2.14e-1)" "unprognostic (7.60e-3)" "unprognostic (1.22e-2)" "unprognostic (2.38e-1)" "unprognostic (3.06e-2)" "unprognostic (3.64e-1)" "unprognostic (8.71e-2)" "unprognostic (2.01e-1)" "unprognostic (2.30e-2)" 11.4 16.7 8.4 3.2 8.3 6.3 12.6 8.5 15.2 7.7 7.9 10.0 4.5 7.9 0.0 11.0 8.4 1.2 15.4 8.1 8.9 14.2 18.0 7.4 3.9 8.9 8.7 5.5 14.8 1.5 6.6 1.7 8.6 11.1 0.2 0.1 10.6 1.9 16.4 14.3 9.8 1.3 9.0 11.7 15.4 29.7 8.9 0.6 8.9 0.0 0.7 10.0 7.5 9.3 15.2 56.0 0.5 12.6 3.2 0.3 9.5 7.3 0.2 0.1 1.4 14.9 14.1 4.7 12.6 0.0 7.8 13.1 0.0 10.0 0.0 7.7 29.4 4.2 26.1 37.2 22.9 3.0 11.1 4.8 6.8 2.9 3.1 0.7 5.3 22.3 7.3 7.2 1.1 38.3 10.7 12.4 6.9 7.9 24.9 9.7 0.4 20.5 2.9 8.2 2.4 11.2 3.1 19.0 27.6 0.2 27.4 17.1 4.5 10.8 7.2 12.2 8.4 19.8 7.9 6.5 14.6 11.3 11.0 18.6 23.6 18.4 23.5 20.8 25.1 26.4 31.9 27.0 22.9 28.6 33.5 26.0 17.1 35.5 22.6 31.2 30.6 23.8 8.4 8.3 8.5 15.2 8.1 8.9 8.9 8.7 8.6 9.0 8.9 9.3 17.9 32.1 17.1 7.5 26.1 8.5 21.5 48.6 21.6 19.9 40.3 40.0 16.2 30.0 26.1 23.9 6.2 37.1 24.8 43.4 72.4 38.1 85.7 29.9 25.6 19.2 21.7 38.1 8.3 47.9 28.8 20.6 28.1 26.9 14.0 26.1 23.6 55.0 44.2 23.5 7.7 35.5 50.8 34.2 11.1 34.6 33.2 21.0 16.0 5.6 41.2 41.3 47.4 7.5 12.6 43.9 41.5 23.7 19.7 40.4 63.4 89.3 36.0 30.9 26.3 11.9 18.5 95.7 20.4 35.8 8.5 27.9 29.5 56.5 31.6 26.6 OXR1 TLDC3 ENSG00000164830 "Oxidation resistance 1" Q8N573 8 106270144-106752694 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Stress response" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 1458.0;Inhibitory neurons: 1366.9;Late spermatids: 405.5;Microglial cells: 496.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 106.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027375, HPA027380, HPA027395" Enhanced Approved Vesicles NA NA 12000 "Cluster 38: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA027375: AB_10600087, HPA027380: AB_10601569, HPA027395: AB_10601554" "unprognostic (8.16e-3)" "unprognostic (1.39e-1)" "unprognostic (5.52e-2)" "unprognostic (3.12e-1)" "unprognostic (4.84e-2)" "unprognostic (2.84e-2)" "unprognostic (1.17e-1)" "unprognostic (3.67e-1)" "unprognostic (2.82e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (3.85e-4)" "unprognostic (6.59e-2)" "prognostic favorable (5.82e-5)" "unprognostic (1.89e-1)" "unprognostic (1.32e-1)" "unprognostic (2.58e-1)" "unprognostic (2.86e-1)" 28.7 57.7 19.2 11.1 27.8 18.6 29.0 14.0 50.3 30.6 0.0 20.1 14.2 27.7 54.5 28.7 22.4 22.1 30.5 25.7 4.3 29.7 38.3 20.0 14.4 19.2 6.4 27.0 17.1 23.9 12.2 17.0 21.3 21.1 21.7 79.5 48.6 47.6 52.1 27.4 12.2 21.7 1.8 19.5 27.3 56.1 10.7 22.2 21.3 59.6 16.4 23.7 17.9 22.2 29.5 11.0 32.3 6.5 41.2 51.4 15.0 23.7 28.3 21.6 27.5 9.7 35.6 29.6 26.8 25.6 13.2 20.4 18.5 21.2 37.3 24.9 20.0 39.8 15.3 18.0 25.5 12.8 22.8 30.3 32.1 23.7 34.9 30.0 24.7 24.2 20.3 106.5 24.6 26.2 38.3 17.3 4.2 43.5 19.4 9.9 25.7 55.7 24.0 36.8 19.4 6.0 10.5 7.3 25.8 14.1 34.1 21.2 18.4 24.6 17.1 22.6 15.6 19.7 13.3 12.1 29.2 3.7 30.9 38.1 9.3 17.8 3.9 17.6 6.5 11.4 6.7 6.2 11.2 7.9 16.0 7.1 4.7 11.0 19.4 7.9 5.2 7.8 19.2 27.8 14.0 50.3 25.7 4.3 19.2 6.4 21.3 1.8 10.7 22.2 54.9 67.3 25.5 125.0 47.1 67.6 57.2 42.6 60.9 89.8 36.7 33.5 58.2 15.7 37.3 35.0 58.4 32.6 44.1 44.3 33.2 16.6 231.2 75.3 32.1 41.8 27.5 19.5 1458.0 17.0 20.0 41.3 39.8 65.3 30.4 29.1 44.6 34.5 19.5 26.9 1366.9 28.2 34.6 33.0 41.4 405.5 34.2 36.3 24.9 496.5 41.1 55.6 22.6 294.0 142.6 23.6 24.9 48.9 73.7 60.4 16.5 16.4 53.5 125.8 19.7 46.4 41.6 140.4 51.6 56.7 75.6 71.1 26.5 33.5 26.4 86.1 P3H1 "GROS1, LEPRE1, LEPRECAN, MGC117314" ENSG00000117385 "Prolyl 3-hydroxylase 1" Q32P28 1 42746335-42767084 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 47.9;Extravillous trophoblasts: 56.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 193.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012113, HPA016980" Approved Approved Nucleoli,Vesicles "Intracellular and membrane" NA NA 18000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles Nucleoli "HPA012113: AB_2668626, HPA016980: AB_2669498" "unprognostic (3.24e-1)" "unprognostic (1.04e-1)" "unprognostic (9.37e-2)" "unprognostic (4.57e-1)" "unprognostic (2.03e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.95e-7)" "unprognostic (5.41e-2)" "unprognostic (2.70e-3)" "unprognostic (9.16e-2)" "unprognostic (2.21e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.41e-2)" "unprognostic (1.23e-1)" "unprognostic (2.67e-2)" "unprognostic (1.60e-3)" 12.4 11.1 3.6 8.7 3.5 6.1 10.2 3.6 4.4 13.4 7.3 8.3 2.4 13.8 6.1 4.4 9.8 12.0 9.1 3.8 3.8 7.2 13.3 11.6 5.1 5.2 3.5 12.8 6.8 5.9 15.5 37.4 3.8 7.5 5.4 1.3 6.7 5.9 3.0 7.6 7.4 20.3 3.4 11.5 6.7 15.2 3.8 7.6 7.6 3.9 5.1 12.3 8.5 3.6 8.7 22.3 48.7 115.0 112.8 85.4 20.1 101.8 131.9 71.9 121.7 11.3 18.8 13.0 79.7 193.0 29.2 7.8 20.9 25.9 49.2 19.5 26.3 30.5 32.2 32.6 65.2 30.9 34.0 73.8 17.4 72.6 30.9 102.4 102.9 18.3 17.5 16.1 49.0 4.7 20.6 17.8 53.1 4.7 16.0 19.9 71.9 17.7 38.2 4.9 10.2 17.3 62.5 1.7 45.8 85.2 3.7 127.0 85.1 53.8 47.2 43.4 41.2 14.5 17.5 11.9 61.5 41.5 77.0 5.0 18.9 16.8 8.3 20.4 8.8 4.1 6.3 7.0 23.6 3.3 5.1 5.3 1.8 17.8 26.3 10.9 12.4 9.3 3.6 3.5 3.6 4.4 3.8 3.8 5.2 3.5 3.8 3.4 3.8 3.6 13.7 3.2 2.3 5.9 10.5 0.0 6.4 0.0 6.2 10.2 4.5 6.5 5.0 7.2 0.6 11.0 25.0 47.9 11.1 0.4 0.0 11.5 17.1 3.2 30.1 16.4 6.1 11.3 12.9 7.6 56.6 34.4 3.6 4.4 1.3 28.8 16.8 11.3 17.6 15.2 10.8 2.5 0.0 8.7 0.0 10.8 19.3 11.7 0.0 9.4 10.5 3.5 6.2 9.5 6.9 7.4 2.0 16.1 11.2 3.4 1.7 1.9 0.7 22.1 0.0 17.2 22.3 30.6 18.8 3.5 0.0 17.5 9.6 27.0 1.9 4.5 P3H2 "FLJ10718, LEPREL1, MLAT4" ENSG00000090530 "Prolyl 3-hydroxylase 2" Q8IVL5 3 189956728-190122437 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 80.3;Granulosa cells: 124.1;Microglial cells: 91.8;Theca cells: 74.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 22 "plasmacytoid DC: 28.9" "Lineage enriched" "Detected in single" 90 "dendritic cells: 28.9" "Cell line enhanced" "Detected in many" "GAMG: 120.2;HaCaT: 109.9;RPTEC TERT1: 109.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007890, HPA013355, HPA013611" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus" "Nucleoplasm, Vesicles, Cytosol" "HPA007890: AB_1852796, HPA013355: AB_1852798, HPA013611: " "unprognostic (4.90e-2)" "unprognostic (1.57e-1)" "unprognostic (3.76e-1)" "unprognostic (4.32e-3)" "unprognostic (1.97e-2)" "unprognostic (7.75e-2)" "unprognostic (9.68e-2)" "unprognostic (2.17e-1)" "unprognostic (3.15e-1)" "unprognostic (1.19e-1)" "unprognostic (1.03e-3)" "unprognostic (1.60e-1)" "unprognostic (1.15e-2)" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.10e-1)" "unprognostic (4.01e-2)" 4.9 41.6 2.8 4.9 3.1 1.0 6.5 3.0 3.1 17.0 1.8 24.0 2.7 17.6 18.5 11.0 8.0 4.8 8.8 3.3 4.8 51.3 7.0 28.7 2.4 7.6 4.7 16.1 3.6 2.3 8.2 9.2 6.7 37.6 10.4 19.3 4.9 26.5 1.2 17.8 6.7 32.4 5.2 54.8 23.9 4.2 4.9 5.2 3.0 1.7 2.0 11.9 19.9 8.3 46.9 18.2 35.1 0.2 0.6 1.4 42.1 48.7 19.3 7.8 12.6 15.0 18.0 0.1 27.1 8.6 120.2 109.9 0.1 65.3 16.3 0.4 6.2 0.1 12.1 0.3 35.4 0.2 0.3 16.9 21.4 15.2 5.4 73.5 1.4 0.1 0.1 0.4 12.3 1.1 0.1 0.4 11.0 31.3 3.7 0.1 7.1 2.8 109.8 77.5 2.5 0.3 66.1 3.7 29.3 51.1 0.1 0.7 24.4 45.9 16.8 0.4 8.9 3.4 0.2 0.5 10.6 0.2 60.2 0.3 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.1 0.0 28.9 0.0 0.2 2.8 3.1 3.0 3.1 3.3 4.8 7.6 4.7 6.7 5.2 4.9 8.3 5.7 48.1 80.3 19.2 1.0 0.0 7.7 0.0 13.6 2.3 1.6 9.9 1.0 2.8 3.1 44.1 4.2 42.0 9.5 19.8 5.9 4.7 19.6 2.0 27.3 10.5 0.0 2.7 55.6 0.8 14.7 10.3 8.6 1.5 1.3 124.1 32.5 0.8 11.4 10.1 60.4 0.5 0.0 3.2 0.0 14.9 4.7 5.6 0.0 91.8 0.8 44.5 0.0 43.7 4.4 30.6 1.9 0.0 0.2 15.1 0.0 26.2 0.0 1.2 0.0 10.9 45.2 0.5 0.9 13.5 0.0 38.6 0.7 74.3 2.1 3.9 P3H4 "LEPREL4, NO55, SC65" ENSG00000141696 "Prolyl 3-hydroxylase family member 4 (inactive)" Q92791 17 41801947-41812604 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 3.9;MAIT T-cell: 5.0;memory CD4 T-cell: 2.5;memory CD8 T-cell: 2.7;naive CD4 T-cell: 3.0;naive CD8 T-cell: 3.9;NK-cell: 8.5" "Group enriched" "Detected in many" 10 "NK-cells: 8.5;T-cells: 5.0" "Cell line enriched" "Detected in many" 13 "OE19: 1032.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA022520 Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum, Vesicles" "HPA022520: " "unprognostic (9.11e-2)" "unprognostic (3.72e-3)" "unprognostic (3.66e-2)" "unprognostic (3.72e-2)" "unprognostic (8.69e-3)" "unprognostic (4.32e-2)" "unprognostic (2.16e-3)" "unprognostic (1.94e-1)" "unprognostic (2.47e-2)" "unprognostic (1.48e-1)" "unprognostic (1.19e-1)" "unprognostic (4.03e-2)" "prognostic unfavorable (4.48e-6)" "unprognostic (1.47e-1)" "unprognostic (1.23e-1)" "unprognostic (8.96e-2)" "unprognostic (1.96e-3)" 5.1 11.6 5.4 5.5 5.6 0.5 4.9 7.3 6.6 10.0 7.5 6.2 7.6 10.7 4.9 2.8 7.7 6.8 8.8 4.6 6.8 7.8 2.3 6.0 2.7 5.2 4.9 7.9 12.9 11.5 10.5 12.1 4.9 7.3 4.2 1.3 10.4 7.2 4.8 7.4 6.5 10.1 4.5 3.3 5.2 2.3 6.6 1.3 12.2 2.0 1.6 7.2 6.4 4.5 9.2 45.0 27.4 70.8 29.1 28.1 26.9 75.5 33.6 25.6 35.0 22.3 12.4 1.4 30.6 58.7 19.5 16.4 23.6 32.3 10.1 21.0 35.5 11.4 44.1 30.3 35.4 2.3 3.6 29.5 9.5 22.3 20.3 61.0 32.6 3.2 2.2 11.6 16.7 31.6 0.6 6.8 17.1 1032.2 25.2 25.3 30.1 31.4 16.5 2.7 13.2 29.0 13.3 81.2 28.9 18.1 46.8 7.4 34.3 24.5 35.7 46.2 34.1 10.7 2.6 0.2 37.7 11.1 38.5 0.0 0.2 0.0 3.9 0.0 5.0 0.6 2.5 2.7 0.2 0.6 3.0 3.9 0.0 8.5 0.0 0.0 0.7 1.5 5.4 5.6 7.3 6.6 4.6 6.8 5.2 4.9 4.9 4.5 6.6 4.5 7.3 0.0 7.8 12.1 1.5 0.0 5.4 0.0 6.2 3.6 11.6 10.8 10.7 11.5 1.8 5.5 8.4 10.8 3.6 7.2 7.9 21.6 0.5 2.7 25.3 11.0 2.4 7.0 6.4 6.5 27.3 26.6 16.8 7.7 1.3 17.7 11.0 1.9 2.8 26.9 4.4 13.0 0.0 1.2 0.0 0.8 21.1 1.0 0.0 4.7 1.2 9.6 13.4 6.0 1.5 7.1 9.5 20.7 2.8 9.6 26.8 5.9 0.7 2.7 19.7 13.1 16.7 2.7 10.0 1.9 0.0 5.3 3.2 19.1 9.8 2.0 P4HA1 "C-P4Halpha(I), P4HA" ENSG00000122884 "Prolyl 4-hydroxylase subunit alpha 1" P13674 10 73007217-73096974 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 494.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007599, HPA026593" Enhanced Supported "Endoplasmic reticulum,Vesicles,Mitochondria" "Intracellular and membrane" Yes No 60000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" "Vesicles, Mitochondria" "HPA007599: AB_1854891, HPA026593: AB_1854892" "prognostic unfavorable (9.01e-4)" "prognostic unfavorable (3.19e-5)" "unprognostic (2.76e-3)" "unprognostic (3.04e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.19e-5)" "unprognostic (2.30e-1)" "prognostic unfavorable (5.10e-4)" "unprognostic (1.28e-1)" "unprognostic (2.29e-1)" "prognostic unfavorable (2.85e-4)" "unprognostic (9.15e-2)" "prognostic unfavorable (9.40e-9)" "unprognostic (3.14e-1)" "unprognostic (4.22e-2)" "unprognostic (1.02e-2)" "unprognostic (5.75e-2)" 28.1 26.0 25.7 20.8 26.4 15.5 26.3 29.6 58.5 31.9 34.7 16.3 11.0 27.0 18.9 10.1 41.1 26.3 38.7 26.5 27.1 35.8 72.8 27.8 16.2 32.9 30.0 34.9 17.5 17.0 11.6 65.3 33.0 20.0 17.4 33.3 13.0 18.4 110.9 17.4 14.4 28.5 30.2 19.6 19.8 19.3 30.1 12.9 13.9 54.0 14.6 29.6 18.2 39.0 84.0 21.2 60.1 117.6 181.2 138.3 50.1 239.9 215.8 90.8 215.8 35.6 63.6 28.4 89.7 239.0 55.1 92.5 38.3 87.7 197.1 36.5 14.5 24.4 18.6 42.5 75.3 45.1 16.4 84.5 50.3 77.7 101.6 494.2 43.5 23.8 38.3 14.7 79.3 22.4 17.9 42.9 21.6 38.9 92.3 16.4 40.2 52.4 51.0 35.6 5.5 33.7 49.2 143.2 58.3 135.0 21.9 41.9 41.9 110.5 44.8 31.3 56.9 81.8 31.3 13.7 198.1 64.5 54.9 1.1 18.8 14.9 6.7 23.5 8.7 8.2 8.1 7.9 20.7 9.2 5.9 6.1 10.4 5.2 25.7 16.6 10.7 9.1 25.7 26.4 29.6 58.5 26.5 27.1 32.9 30.0 33.0 30.2 30.1 39.0 29.0 6.4 28.4 87.1 31.7 36.3 33.0 138.0 22.2 13.5 23.8 15.7 42.0 7.2 69.2 23.9 27.1 31.5 24.9 25.1 0.0 33.1 16.8 85.6 89.2 25.9 10.3 7.2 48.8 19.5 116.4 67.7 14.3 131.4 40.5 16.9 20.0 29.8 43.9 11.8 41.6 9.5 46.8 54.1 75.7 8.1 51.9 51.5 44.4 62.8 39.0 34.0 6.2 86.5 44.8 36.6 27.1 47.0 32.9 24.9 13.5 25.1 94.6 17.2 39.5 37.0 44.7 61.7 34.0 9.8 23.9 33.2 27.7 31.1 7.0 17.6 P4HA2 C-P4Halpha(II) ENSG00000072682 "Prolyl 4-hydroxylase subunit alpha 2" O15460 5 132190147-132295315 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 115.6;Endometrial stromal cells: 96.9;Skeletal myocytes: 109.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HHSteC: 324.2;U-87 MG: 323.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA016997, HPA027824, CAB062557" Enhanced Enhanced "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" No No 13000 "Cluster 1: Neutrophils - Mixed function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum, Vesicles" "CAB062557: AB_2665641, HPA016997: AB_2669501, HPA027824: AB_2672402" "unprognostic (1.30e-3)" "prognostic unfavorable (1.24e-5)" "unprognostic (2.56e-3)" "unprognostic (1.28e-3)" "unprognostic (2.08e-3)" "unprognostic (1.62e-3)" "unprognostic (1.16e-3)" "unprognostic (1.93e-3)" "unprognostic (2.83e-2)" "unprognostic (1.92e-1)" "unprognostic (8.98e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (2.77e-7)" "unprognostic (2.50e-2)" "unprognostic (1.61e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.12e-4)" 17.4 11.7 11.9 16.1 12.1 2.4 12.3 11.4 28.4 29.5 42.2 28.7 22.6 31.1 76.7 19.6 29.6 19.9 40.6 14.4 17.2 80.0 10.5 31.5 2.5 11.4 14.3 8.6 70.7 10.9 19.9 35.1 19.1 10.8 32.7 7.8 32.5 17.1 13.0 16.7 26.8 52.6 10.0 8.7 20.5 9.7 16.8 11.3 20.7 22.9 8.3 22.9 22.3 12.2 57.0 34.9 11.2 57.2 149.2 173.7 61.1 261.9 223.7 108.9 265.0 78.9 50.3 1.5 71.8 283.3 120.5 70.2 33.2 136.5 172.7 41.5 11.9 0.6 48.1 49.0 324.2 0.0 33.9 104.6 193.1 128.8 117.4 162.7 59.1 0.1 21.2 3.6 134.0 23.2 0.2 0.5 3.0 53.7 27.2 0.9 3.6 9.8 31.1 11.0 5.4 15.8 67.7 22.3 47.9 84.1 28.4 3.7 88.9 171.7 63.5 51.0 57.1 24.4 28.1 11.8 323.4 0.4 48.3 0.0 0.4 0.0 0.8 0.3 0.7 0.0 0.4 0.1 0.2 0.0 0.0 0.1 1.0 0.9 0.0 0.3 0.0 0.2 11.9 12.1 11.4 28.4 14.4 17.2 11.4 14.3 19.1 10.0 16.8 12.2 13.0 35.3 10.3 7.5 1.1 16.8 43.6 115.6 23.9 11.6 9.5 9.5 13.3 8.6 36.9 11.0 22.9 2.6 0.3 43.2 5.9 68.3 1.4 26.7 96.9 12.2 15.0 0.0 7.7 71.8 70.2 61.6 12.8 28.0 5.7 11.1 9.3 7.8 7.6 0.0 7.7 18.6 32.6 1.3 5.5 2.0 8.1 4.4 30.2 2.8 2.6 6.8 0.0 1.5 1.2 81.9 41.0 5.3 3.0 19.6 41.4 44.6 71.9 5.2 26.3 109.4 47.6 23.0 29.1 6.8 9.8 7.5 4.8 10.4 13.8 15.3 P4HTM "EGLN4, FLJ20262, HIFPH4, P4H-TM, PH-4, PH4, PHD4" ENSG00000178467 "Prolyl 4-hydroxylase, transmembrane" Q9NXG6 3 48989889-49007153 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Dioxygenase, Oxidoreductase" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 155.3;Respiratory ciliated cells: 169.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007199 Supported Uncertain Vesicles,Cytosol NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 25: RPMI-8226 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "Vesicles, Cytosol" "HPA007199: AB_1855272" "unprognostic (1.95e-2)" "unprognostic (3.12e-2)" "unprognostic (9.47e-2)" "prognostic favorable (8.18e-4)" "unprognostic (7.78e-2)" "unprognostic (1.05e-1)" "unprognostic (6.47e-2)" "unprognostic (2.02e-2)" "unprognostic (1.89e-2)" "unprognostic (3.78e-2)" "unprognostic (2.51e-3)" "unprognostic (1.54e-2)" "prognostic favorable (3.28e-5)" "unprognostic (1.10e-2)" "unprognostic (3.51e-1)" "unprognostic (2.60e-2)" "unprognostic (9.65e-3)" 13.3 37.1 50.6 4.9 53.3 5.9 12.4 44.3 67.9 18.4 89.7 14.7 12.1 17.6 18.7 8.2 39.8 11.2 26.2 53.5 57.3 29.8 11.9 15.7 6.5 52.2 49.6 20.0 38.5 39.4 75.9 11.0 51.5 18.5 7.4 16.4 19.6 16.8 15.2 10.1 13.0 7.4 45.8 10.7 25.1 23.6 53.3 5.5 26.5 11.3 3.8 12.8 13.1 49.6 8.6 27.9 4.8 0.1 15.5 17.6 0.4 16.8 24.6 13.2 14.8 6.3 55.6 8.1 15.8 21.6 10.5 4.8 12.5 6.6 4.1 30.4 19.5 0.0 42.1 0.0 38.6 8.3 0.2 11.0 6.3 13.4 1.1 51.4 15.0 0.1 0.0 37.9 6.5 48.1 1.2 1.0 6.8 52.6 31.2 0.0 0.0 53.5 24.4 15.9 20.9 0.2 17.7 25.0 0.1 1.1 20.1 13.1 9.9 8.0 6.1 19.9 14.5 50.0 28.6 0.1 54.9 0.7 7.1 8.0 9.0 5.9 6.7 3.5 9.6 8.4 12.3 11.7 9.4 15.9 13.0 8.3 0.8 5.9 4.5 1.6 17.0 6.0 50.6 53.3 44.3 67.9 53.5 57.3 52.2 49.6 51.5 45.8 53.3 49.6 15.1 22.4 17.3 36.2 16.1 9.2 34.6 41.1 12.5 72.9 28.7 23.0 12.0 41.5 44.0 46.0 87.6 31.4 13.4 27.4 19.6 38.3 138.4 106.4 23.7 12.6 80.9 12.4 55.7 39.1 9.9 28.1 48.9 31.2 22.9 31.6 15.4 8.5 16.8 117.8 48.6 40.4 65.1 6.3 12.8 155.3 30.4 13.0 12.4 20.6 11.3 58.4 14.4 17.1 32.3 23.6 51.8 25.9 28.9 24.4 56.2 30.4 169.4 72.5 19.7 32.9 24.7 32.5 7.0 12.9 10.4 26.1 25.0 23.9 40.9 31.2 PACRGL "C4orf28, MGC29898" ENSG00000163138 "Parkin coregulated like" Q8N7B6 4 20696282-20752907 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 211.7;Late spermatids: 88.4;Oligodendrocytes: 66.9;Spermatocytes: 90.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054666 Approved Nucleoplasm,Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Vesicles" "HPA054666: AB_2682564" "unprognostic (1.32e-1)" "unprognostic (1.71e-1)" "unprognostic (6.90e-3)" "unprognostic (5.15e-2)" "unprognostic (1.15e-1)" "unprognostic (1.55e-2)" "unprognostic (1.09e-2)" "unprognostic (2.97e-1)" "unprognostic (4.55e-2)" "unprognostic (2.20e-2)" "unprognostic (5.08e-2)" "unprognostic (3.35e-2)" "unprognostic (1.25e-2)" "unprognostic (6.74e-3)" "unprognostic (3.63e-2)" "unprognostic (1.07e-2)" "prognostic favorable (4.85e-4)" 7.6 8.5 9.6 5.7 10.1 4.0 16.0 3.6 11.9 8.2 16.6 8.5 6.6 12.9 14.3 9.2 13.5 9.6 9.2 11.9 11.4 8.2 4.5 7.3 7.9 6.5 7.3 13.5 7.0 11.1 8.0 7.4 5.4 10.5 8.6 15.0 7.0 10.1 7.2 14.7 7.8 10.1 6.5 7.1 7.7 28.1 12.1 5.4 15.1 8.1 6.3 9.2 7.7 12.1 12.5 8.9 16.8 12.1 23.7 21.9 8.0 15.9 11.9 13.4 17.5 8.9 28.2 11.9 11.5 8.7 24.1 6.4 9.3 10.9 24.3 4.3 8.6 8.4 16.1 13.7 11.8 17.6 8.9 14.4 18.8 17.9 17.4 14.5 14.9 12.2 13.9 7.6 12.7 9.1 18.1 17.0 20.3 11.0 12.3 9.4 18.4 7.4 12.9 7.8 25.4 17.9 12.5 5.6 12.2 9.4 11.5 10.0 12.0 14.4 13.5 20.0 22.6 8.0 2.5 11.3 21.7 10.9 25.5 0.0 1.5 0.7 1.3 2.4 2.9 2.0 1.4 1.3 2.7 1.8 2.2 1.5 0.6 2.3 2.0 3.5 1.9 1.4 9.6 10.1 3.6 11.9 11.9 11.4 6.5 7.3 5.4 6.5 12.1 12.1 6.7 9.6 6.4 37.9 4.9 13.6 10.6 6.8 13.1 5.8 8.2 7.0 5.4 8.6 8.6 7.3 4.2 5.5 4.9 5.5 7.9 9.7 211.7 15.8 8.6 7.4 9.0 5.7 48.0 9.1 6.9 9.7 6.6 4.8 2.5 7.9 7.5 3.1 4.2 5.0 44.9 5.9 6.1 4.9 4.0 88.4 13.1 4.6 5.4 31.9 3.3 9.7 3.1 35.7 66.9 8.7 9.1 12.4 2.1 9.7 5.5 6.2 27.1 12.1 13.1 9.2 7.3 90.6 30.3 9.0 10.5 5.9 3.6 9.3 6.7 8.0 PACSIN1 SDPI ENSG00000124507 "Protein kinase C and casein kinase substrate in neurons 1" Q9BY11 6 34466061-34535229 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "brain: 149.3;retina: 64.3" "Group enriched" "Detected in some" 4 "Bipolar cells: 76.1;Cone photoreceptor cells: 81.3;dendritic cells: 24.9;Excitatory neurons: 49.9;Horizontal cells: 69.0;Inhibitory neurons: 47.6;Rod photoreceptor cells: 89.4" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 15.8" "Lineage enriched" "Detected in many" 4 "dendritic cells: 15.8" "Cell line enhanced" "Detected in some" "MCF7: 12.1;RPMI-8226: 14.0;T-47d: 21.5;U-266/84: 16.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009929, HPA028852, HPA055491" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 6: T47d - Mammary gland" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles" "CAB009929: AB_2268057, HPA028852: AB_10602812, HPA055491: AB_2682834" "unprognostic (3.33e-1)" "unprognostic (1.21e-1)" "unprognostic (6.33e-2)" "unprognostic (2.97e-1)" "unprognostic (1.72e-2)" "unprognostic (2.47e-3)" "unprognostic (2.14e-2)" "unprognostic (2.65e-1)" "unprognostic (1.74e-1)" "unprognostic (6.63e-2)" "unprognostic (3.95e-4)" "unprognostic (9.12e-2)" "unprognostic (3.02e-2)" "unprognostic (4.18e-2)" "unprognostic (9.90e-2)" "unprognostic (5.50e-2)" "unprognostic (9.33e-2)" 0.2 0.7 40.9 1.2 72.9 0.8 0.2 0.0 149.3 0.3 0.0 0.8 0.5 0.5 0.1 0.1 0.6 0.3 5.4 64.4 0.0 1.4 0.2 0.2 3.6 58.8 10.0 0.6 5.1 1.7 6.3 0.0 55.4 0.7 0.2 64.3 1.0 0.4 0.2 0.3 1.4 0.1 0.0 1.3 1.3 0.8 3.9 1.3 0.2 0.1 2.2 0.4 0.3 59.5 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 4.5 0.8 0.0 0.0 0.1 1.4 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.4 1.1 0.1 0.0 12.1 0.7 0.0 2.8 0.1 0.1 0.1 0.0 14.0 0.0 0.4 4.2 0.3 0.0 2.2 0.0 0.4 21.5 2.4 0.0 0.0 0.3 0.0 0.0 3.5 16.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 3.6 0.0 15.8 0.0 0.1 40.9 72.9 0.0 149.3 64.4 0.0 58.8 10.0 55.4 0.0 3.9 59.5 0.2 0.0 0.0 2.3 0.3 0.0 0.1 0.0 0.0 76.1 0.2 0.1 4.5 0.0 0.0 0.0 81.3 0.1 24.9 0.1 0.0 0.3 0.2 1.3 0.2 0.6 0.0 0.0 49.9 0.7 0.0 0.1 0.5 2.0 0.0 0.2 0.0 0.0 0.0 69.0 47.6 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 6.5 0.0 12.7 1.0 1.0 2.0 0.1 0.0 0.0 0.2 0.1 0.0 2.3 0.0 89.4 0.0 0.2 0.2 0.4 1.7 0.0 0.0 0.0 0.6 0.1 0.1 0.1 PACSIN2 SDPII ENSG00000100266 "Protein kinase C and casein kinase substrate in neurons 2" Q9UNF0 22 42835412-43015149 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 95.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049854, HPA056520" Enhanced Supported "Nuclear speckles,Vesicles,Plasma membrane,Cytosol" NA NA 2400000 "Cluster 52: Eosinophils - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles, Vesicles, Cytosol" "Plasma membrane" "HPA049854: AB_2680915, HPA056520: AB_2683163" "unprognostic (5.62e-3)" "unprognostic (1.22e-1)" "unprognostic (1.71e-2)" "unprognostic (1.64e-3)" "unprognostic (1.63e-2)" "unprognostic (3.96e-1)" "prognostic unfavorable (7.33e-4)" "unprognostic (4.48e-2)" "unprognostic (3.40e-2)" "unprognostic (2.82e-3)" "unprognostic (3.09e-2)" "unprognostic (1.00e-1)" "prognostic favorable (1.09e-13)" "unprognostic (2.87e-1)" "unprognostic (1.11e-1)" "unprognostic (6.20e-2)" "unprognostic (2.95e-1)" 40.8 74.3 25.7 37.1 29.1 29.3 40.7 34.2 27.3 37.5 32.3 61.7 40.8 39.1 21.2 34.1 35.3 45.3 55.7 27.7 39.2 47.1 41.1 50.9 34.2 40.5 36.8 31.4 162.4 29.4 39.9 34.2 40.8 47.0 41.6 28.2 43.5 27.4 49.8 39.5 38.1 30.4 30.7 35.9 51.5 19.5 32.5 28.7 43.9 42.4 26.4 36.5 34.5 31.1 76.3 78.3 64.6 41.5 32.6 34.6 52.9 67.8 40.7 59.9 49.7 82.1 43.8 35.2 56.1 50.6 40.8 52.8 42.5 72.1 39.3 36.1 42.4 56.8 39.4 117.8 46.1 40.5 118.1 33.4 69.8 79.1 34.3 48.7 49.9 32.1 49.9 24.9 52.2 49.7 43.1 63.3 35.6 110.4 32.7 52.3 96.5 23.8 68.9 44.4 41.9 18.7 81.1 55.2 155.8 41.5 40.1 53.1 74.3 44.5 56.4 50.0 40.5 18.4 27.2 38.4 42.7 35.4 99.1 26.1 18.5 47.4 6.8 32.2 7.3 11.3 7.8 5.8 21.5 11.6 7.6 5.8 95.7 16.8 33.9 7.9 12.1 14.1 25.7 29.1 34.2 27.3 27.7 39.2 40.5 36.8 40.8 30.7 32.5 31.1 31.7 70.5 60.6 20.2 20.6 23.2 43.4 23.9 21.1 15.7 37.4 31.1 26.3 24.3 37.2 46.0 39.6 34.4 19.9 142.6 45.0 80.2 3.6 51.6 31.3 28.6 24.7 12.6 22.7 65.4 29.6 20.9 36.7 57.4 71.0 14.7 16.1 22.3 42.7 6.7 41.0 49.5 30.5 38.5 50.0 6.2 21.8 44.9 83.6 54.4 51.3 8.4 7.2 29.1 19.5 70.9 62.3 23.3 13.1 50.6 32.0 55.0 30.7 24.9 92.1 23.5 82.9 22.6 27.6 22.5 16.9 48.2 19.1 13.8 42.2 30.3 PADI3 PDI3 ENSG00000142619 "Peptidyl arginine deiminase 3" Q9ULW8 1 17249098-17284233 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "esophagus: 17.0;urinary bladder: 25.6" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.8;Ionocytes: 6.1;Squamous epithelial cells: 1.1;Urothelial cells: 7.9" "Cancer enriched" "Detected in many" 4 "urothelial cancer: 48.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 14.0;RT4: 17.4;T-47d: 12.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA043739 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" Vesicles Nucleoplasm "HPA043739: AB_10959466" "unprognostic (4.47e-2)" "unprognostic (9.32e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.22e-4)" "unprognostic (1.05e-3)" "unprognostic (6.66e-2)" "unprognostic (3.10e-3)" "unprognostic (5.88e-2)" "unprognostic (2.06e-4)" "unprognostic (1.03e-1)" "unprognostic (3.47e-4)" "unprognostic (1.76e-1)" "prognostic unfavorable (1.55e-11)" "unprognostic (2.40e-2)" "unprognostic (4.73e-3)" "unprognostic (2.64e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 17.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.9 3.4 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 25.6 3.6 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 14.0 0.0 1.4 0.3 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 17.4 0.0 0.0 0.0 2.5 0.1 0.1 12.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.2 0.0 7.9 PAG1 "CBP, PAG" ENSG00000076641 "Phosphoprotein membrane anchor with glycosphingolipid microdomains 1" Q9NWQ8 8 80967810-81112068 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 169.6;granulocytes: 124.5;Melanocytes: 140.5;Microglial cells: 166.8;Sertoli cells: 124.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 35.4;HMC-1: 45.5;SK-MEL-30: 36.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001632, HPA066527" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Vesicles, Plasma membrane" "HPA001632: AB_1079557, HPA066527: AB_2685685" "unprognostic (8.30e-2)" "unprognostic (3.84e-2)" "unprognostic (5.89e-2)" "unprognostic (4.79e-2)" "unprognostic (1.55e-1)" "unprognostic (6.91e-2)" "unprognostic (3.71e-3)" "unprognostic (3.84e-2)" "unprognostic (3.73e-2)" "unprognostic (4.52e-2)" "unprognostic (2.93e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (1.24e-6)" "unprognostic (2.12e-1)" "prognostic unfavorable (6.82e-4)" "unprognostic (1.80e-1)" "unprognostic (1.94e-3)" 3.9 3.1 3.4 9.0 3.5 12.3 2.0 14.8 4.0 1.8 4.3 9.2 7.6 1.9 2.2 1.6 1.8 7.1 4.7 2.8 3.7 1.7 4.7 14.9 14.5 4.5 4.5 1.2 14.9 0.9 2.0 16.0 4.9 2.6 8.7 5.0 3.7 2.1 1.3 4.3 9.0 3.0 4.9 9.1 4.4 0.7 5.2 10.4 1.8 2.1 14.0 4.8 2.6 5.6 0.1 0.1 4.8 0.2 8.9 8.5 0.1 2.0 15.5 1.0 1.9 0.3 0.1 35.4 0.2 0.5 7.6 1.5 0.1 1.8 0.9 0.9 4.5 20.8 0.3 0.0 9.1 3.4 45.5 4.1 1.2 8.9 8.2 0.9 0.0 6.2 0.2 0.1 14.8 0.3 12.6 0.3 0.4 8.1 1.4 9.5 2.4 0.1 1.6 7.6 1.0 1.7 0.0 0.3 36.1 0.8 1.2 3.5 0.3 1.1 0.6 0.0 1.2 5.7 1.6 12.3 9.7 11.7 8.5 13.1 1.4 2.0 2.5 6.4 6.1 2.0 6.2 4.4 1.9 1.6 4.9 3.8 2.3 1.7 14.6 4.1 7.2 2.7 3.4 3.5 14.8 4.0 2.8 3.7 4.5 4.5 4.9 4.9 5.2 5.6 6.2 0.0 12.4 40.8 37.0 31.5 3.9 5.2 0.6 39.7 2.2 2.2 15.4 10.0 14.0 3.7 0.0 0.8 39.0 169.6 0.0 4.0 3.5 0.6 4.4 10.9 3.6 3.8 57.5 6.5 26.2 24.3 8.2 1.1 124.5 97.0 12.5 10.3 27.1 63.9 60.0 23.2 6.1 73.6 26.2 2.1 2.5 79.1 140.5 166.8 40.8 34.9 19.6 82.4 75.3 2.0 62.1 7.9 38.4 7.7 109.3 0.4 0.8 3.2 124.9 32.3 37.1 0.2 3.0 3.8 22.6 2.3 78.1 11.8 27.4 13.7 PAGE4 "CT16.7, GAGEC1, PAGE-4" ENSG00000101951 "PAGE family member 4" O60829 X 49829260-49834264 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "epididymis: 871.9;placenta: 1023.1" "Group enriched" "Detected in some" 10 "Cytotrophoblasts: 13314.7;Syncytiotrophoblasts: 8524.1" "Group enriched" "Detected in some" 17 "liver cancer: 14.8;prostate cancer: 7.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 10.2;U-266/70: 11.7;U-266/84: 45.1" "Not detected" "Not detected" HPA023880 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "Golgi apparatus" "HPA023880: AB_1854930" "unprognostic (8.56e-2)" "unprognostic (1.47e-1)" "unprognostic (1.04e-1)" "unprognostic (4.82e-3)" "unprognostic (5.37e-2)" 0.3 5.7 0.1 0.3 0.2 0.0 0.0 0.1 0.5 7.0 0.1 0.2 0.4 51.2 871.9 0.0 21.4 0.0 0.4 0.1 0.2 3.1 0.3 0.2 0.0 0.1 0.1 3.7 2.5 0.0 1.3 1023.1 0.1 171.8 0.0 0.0 0.6 77.2 2.3 0.0 0.3 24.2 0.0 0.3 0.2 5.6 0.1 0.1 0.0 0.0 0.0 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 10.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.5 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.1 0.0 0.1 11.7 45.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.5 0.1 0.2 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 13314.7 0.0 0.0 0.0 0.0 4.4 1.9 72.5 25.9 0.0 0.0 0.0 0.0 905.4 72.5 0.0 1.9 0.0 0.0 0.0 0.0 1052.1 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 1.7 48.8 20.7 0.0 0.0 8524.1 0.3 0.0 0.0 0.1 PAH PH ENSG00000171759 "Phenylalanine hydroxylase" P00439 12 102836889-102958410 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Phenylalanine catabolism" "Allosteric enzyme, Monooxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "kidney: 496.6;liver: 1408.4" "Group enriched" "Detected in some" 6 "Cholangiocytes: 250.2;Hepatocytes: 807.7;Proximal tubular cells: 344.4" "Cancer enriched" "Detected in some" 17 "liver cancer: 94.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 31 "Hep G2: 238.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028407, HPA031642" Enhanced Approved "Endoplasmic reticulum,Vesicles" No NA 40000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Endoplasmic reticulum, Vesicles" "HPA028407: AB_10601241, HPA031642: AB_2673974" "unprognostic (1.16e-1)" "unprognostic (1.52e-1)" "unprognostic (4.47e-2)" "unprognostic (9.13e-3)" "unprognostic (5.19e-2)" "unprognostic (5.99e-2)" "prognostic favorable (4.30e-4)" "unprognostic (1.27e-1)" "unprognostic (6.60e-2)" "unprognostic (4.45e-3)" "unprognostic (1.94e-3)" "unprognostic (1.83e-1)" "unprognostic (1.10e-2)" "unprognostic (3.51e-1)" "unprognostic (1.64e-1)" "unprognostic (3.96e-2)" "unprognostic (1.68e-2)" 0.2 6.4 2.1 0.0 1.9 0.0 0.2 1.8 3.4 0.1 1.1 0.3 0.1 0.1 0.5 0.0 0.1 79.4 0.0 2.2 2.3 496.6 1408.4 0.0 0.1 2.8 2.3 0.1 9.2 0.8 3.0 0.0 2.3 1.5 0.0 2.4 0.1 0.1 0.0 0.0 0.1 0.0 2.6 0.3 0.4 3.3 2.5 0.7 0.6 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.3 238.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.2 1.0 0.1 0.2 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.9 1.8 3.4 2.2 2.3 2.8 2.3 2.3 2.6 2.5 2.8 0.0 0.0 0.0 1.0 2.7 0.0 0.0 0.0 0.0 1.4 0.2 0.1 0.5 250.2 0.0 5.5 0.0 0.0 0.0 0.0 21.5 2.4 66.8 0.0 0.1 1.1 1.8 21.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 807.7 0.0 3.3 2.3 0.0 0.0 22.2 0.0 15.7 0.6 1.8 0.0 0.0 0.0 0.6 0.0 4.5 0.0 0.0 0.0 1.2 0.0 0.4 0.0 344.4 0.0 0.2 0.0 0.0 0.0 2.1 0.4 0.0 0.0 0.0 3.3 0.0 0.0 0.1 PAIP2 PAIP2A ENSG00000120727 "Poly(A) binding protein interacting protein 2" Q9BPZ3 5 139341587-139369720 "Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 834.4;Late spermatids: 2779.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035945, CAB037212, HPA056766" Approved Supported Vesicles NA NA 21000 "Cluster 5: Granulocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "CAB037212: AB_1841072, HPA035945: AB_10672996, HPA056766: AB_2683231" "unprognostic (1.07e-1)" "unprognostic (1.44e-1)" "unprognostic (1.19e-1)" "unprognostic (5.86e-2)" "unprognostic (7.40e-2)" "unprognostic (3.80e-3)" "unprognostic (7.70e-3)" "unprognostic (8.91e-2)" "unprognostic (4.64e-2)" "unprognostic (2.36e-2)" "unprognostic (2.67e-2)" "unprognostic (3.27e-1)" "unprognostic (2.01e-3)" "unprognostic (2.01e-1)" "unprognostic (2.21e-1)" "unprognostic (3.36e-1)" "unprognostic (6.92e-2)" 103.3 148.6 107.9 77.2 107.9 115.7 90.3 120.0 149.6 77.3 119.9 79.1 44.2 94.1 85.6 68.8 91.6 66.5 173.1 107.8 118.9 104.7 114.2 73.1 109.0 119.5 114.0 112.3 64.2 88.9 96.2 93.7 123.8 84.3 53.9 168.9 92.1 82.4 169.6 48.2 50.0 83.1 119.1 92.1 58.1 169.0 110.0 147.4 74.6 161.9 107.7 81.4 54.3 138.9 91.9 102.7 196.2 118.5 144.0 81.3 95.6 81.9 113.6 104.7 163.6 138.5 86.7 160.7 170.8 62.3 120.1 88.9 173.5 112.5 137.4 155.7 136.4 148.5 145.7 125.8 93.0 92.8 105.4 93.2 92.4 78.5 88.8 112.9 108.7 173.3 143.7 138.6 95.8 121.1 254.3 227.3 118.9 130.5 74.6 140.0 248.1 177.2 84.0 163.2 90.9 165.2 121.2 110.7 251.2 245.4 214.4 192.6 66.9 55.9 67.9 61.3 67.3 200.0 262.6 167.8 98.2 161.6 58.9 569.5 292.2 735.8 286.2 329.3 317.0 378.7 314.7 330.4 292.0 337.7 364.4 356.5 800.5 347.5 380.6 298.7 449.5 577.2 107.9 107.9 120.0 149.6 107.8 118.9 119.5 114.0 123.8 119.1 110.0 138.9 154.8 73.7 87.5 26.4 173.8 159.8 164.3 168.2 79.1 102.4 108.2 98.0 59.7 97.2 100.9 99.3 58.4 198.6 253.1 74.0 170.2 126.4 834.4 228.6 109.2 126.9 97.0 190.0 40.6 115.1 134.1 129.5 38.7 109.0 109.0 108.2 123.1 103.8 142.3 97.6 46.6 57.7 120.1 142.2 196.1 2779.9 160.9 170.6 135.2 29.0 239.2 158.5 247.2 29.7 59.9 122.5 64.7 155.3 146.8 232.8 62.1 256.2 149.4 93.6 170.9 87.7 180.3 432.3 238.1 57.0 208.3 479.7 191.3 145.8 59.5 178.3 PAK2 "PAK65, PAKgamma" ENSG00000180370 "P21 (RAC1) activated kinase 2" Q13177 3 196739857-196832647 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Growth regulation, Host-virus interaction" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB007794 Approved Approved Nucleoplasm,Vesicles NA NA 1700000 "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Vesicles" "CAB007794: AB_562363" "unprognostic (1.03e-2)" "unprognostic (6.34e-2)" "unprognostic (2.52e-1)" "unprognostic (2.50e-2)" "unprognostic (1.32e-1)" "unprognostic (1.80e-1)" "unprognostic (5.18e-3)" "unprognostic (1.85e-2)" "unprognostic (7.97e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (3.36e-4)" "prognostic unfavorable (9.58e-4)" "unprognostic (1.30e-3)" "unprognostic (4.57e-2)" "unprognostic (1.25e-2)" "unprognostic (1.70e-2)" "unprognostic (3.39e-1)" 31.8 18.1 21.2 34.6 24.9 28.1 19.5 25.0 21.7 21.1 19.8 25.6 23.0 21.9 16.0 26.5 20.5 23.8 24.0 19.5 24.6 22.1 33.8 26.3 40.9 26.7 23.4 19.8 18.5 32.6 8.4 33.3 27.7 20.1 26.6 17.4 14.5 18.9 28.3 16.6 22.5 27.0 24.8 43.5 20.9 15.1 23.0 45.1 19.7 25.9 39.4 34.1 16.0 34.1 140.7 49.1 67.6 49.8 47.1 61.9 100.0 69.1 57.0 73.7 66.8 117.5 70.1 89.4 192.7 70.8 75.1 70.2 72.5 66.2 113.6 39.9 35.2 132.2 52.1 92.5 95.0 130.2 122.0 49.6 53.1 66.2 139.2 78.1 74.3 97.3 65.0 107.5 72.9 146.7 124.8 67.2 40.5 74.7 73.4 112.4 38.6 80.9 64.8 96.7 39.6 44.7 92.8 64.7 52.7 51.9 227.0 92.6 76.9 60.9 33.6 64.3 103.1 72.5 138.9 216.4 50.4 127.6 59.1 37.3 20.0 48.0 10.9 23.2 14.7 11.2 12.7 12.6 25.4 11.3 9.1 10.9 47.6 12.2 21.2 9.3 20.7 14.9 21.2 24.9 25.0 21.7 19.5 24.6 26.7 23.4 27.7 24.8 23.0 34.1 164.9 80.1 40.2 37.9 142.8 97.4 89.2 41.8 96.2 42.6 59.7 47.5 59.3 62.9 45.1 82.8 52.1 50.3 135.1 69.6 33.2 71.5 57.1 107.9 112.6 104.0 44.9 72.3 32.2 59.0 101.4 68.9 58.1 96.1 148.8 70.9 66.0 138.6 104.3 55.5 38.9 46.4 57.0 160.5 115.9 75.5 60.9 169.6 33.8 46.9 183.2 63.7 140.1 37.2 61.3 100.4 52.1 45.5 100.0 149.4 58.2 85.2 76.4 45.0 39.5 86.0 75.9 24.5 43.0 103.2 86.2 34.9 139.1 96.3 51.0 124.1 PAK3 "bPAK, hPAK3, MRX30, MRX47" ENSG00000077264 "P21 (RAC1) activated kinase 3" O75914 X 110944285-111227361 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Allosteric enzyme, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 31.9;pancreas: 42.7;pituitary gland: 13.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 104.1;Excitatory neurons: 364.0;Inhibitory neurons: 323.5;Oligodendrocyte precursor cells: 165.9;Peritubular cells: 81.3" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 5 "T-cells: 1.0" "Cell line enhanced" "Detected in some" "EFO-21: 10.8;HAP1: 9.9;HDLM-2: 12.4;NTERA-2: 9.7;SCLC-21H: 12.4;SH-SY5Y: 7.7;U-2197: 7.6;U-251 MG: 13.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044791, HPA060219" Approved Approved Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA044791: , HPA060219: AB_2684223" "unprognostic (1.80e-2)" "unprognostic (1.54e-1)" "unprognostic (1.80e-2)" "unprognostic (3.27e-4)" "unprognostic (2.46e-1)" "unprognostic (5.63e-3)" "unprognostic (7.29e-2)" "unprognostic (3.23e-2)" "unprognostic (1.27e-2)" "unprognostic (3.01e-1)" "unprognostic (6.80e-3)" "unprognostic (1.66e-1)" "unprognostic (1.89e-4)" "unprognostic (5.71e-3)" "unprognostic (6.81e-2)" "unprognostic (1.06e-1)" "unprognostic (3.30e-2)" 1.0 5.2 16.9 1.6 16.2 0.1 5.2 0.0 17.6 2.3 0.0 0.7 0.2 5.4 5.8 0.7 2.5 1.6 0.3 17.8 31.9 0.7 0.2 0.9 1.7 1.6 0.0 6.2 42.7 0.1 13.7 0.6 6.0 3.4 0.7 7.0 2.2 4.8 1.6 1.3 0.5 4.7 0.4 2.0 2.0 2.6 13.2 0.6 6.2 0.4 0.8 0.9 0.7 2.8 0.0 0.7 1.4 0.0 0.0 0.0 0.0 0.3 0.4 1.1 0.0 0.0 0.0 0.0 10.8 1.2 1.6 0.0 9.9 0.6 1.3 12.4 0.4 0.0 1.3 0.0 0.0 0.0 0.4 0.3 0.0 0.1 2.2 5.7 0.0 0.2 0.0 0.5 0.0 0.0 0.1 0.2 9.7 0.0 2.2 0.1 4.3 0.0 0.8 0.0 12.4 7.7 0.0 0.4 0.0 6.6 0.0 0.0 0.0 0.7 4.7 7.6 13.6 0.1 0.1 0.1 1.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 16.9 16.2 0.0 17.6 17.8 31.9 1.6 0.0 6.0 0.4 13.2 2.8 0.9 3.2 1.1 16.0 0.6 0.3 13.3 0.2 0.0 104.1 6.9 10.4 1.0 20.0 0.7 0.0 0.0 0.3 0.2 0.2 0.0 4.7 4.4 1.0 10.8 2.3 3.6 0.0 364.0 13.1 0.4 10.3 10.2 1.7 1.3 21.9 1.4 0.2 0.2 6.7 323.5 0.3 0.0 0.3 5.7 7.0 34.2 1.1 0.0 17.8 0.7 27.5 1.0 165.9 12.0 5.3 0.0 81.3 1.0 1.7 0.0 0.6 0.0 6.0 0.0 1.6 7.8 1.4 1.4 0.3 1.1 6.7 2.4 29.2 0.3 0.9 PAPPA2 "PAPP-A2, PAPPE, PLAC3" ENSG00000116183 "Pappalysin 2" Q9BXP8 1 176463171-176845601 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "placenta: 56.8" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 140.7;Extravillous trophoblasts: 71.9;Muller glia cells: 41.4;Oligodendrocytes: 37.6;Syncytiotrophoblasts: 74.0" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.8;renal cancer: 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-87 MG: 19.8" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "cerebellum: 5.6" "HPA018412, HPA018430" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted in female reproductive system" NA NA 2000000 "Cluster 28: Placenta - Pregnancy" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Endoplasmic reticulum, Vesicles" "HPA018412: AB_1854962, HPA018430: AB_1854961" "unprognostic (2.90e-1)" "unprognostic (1.58e-1)" "unprognostic (1.07e-1)" "unprognostic (3.61e-2)" "unprognostic (9.04e-2)" "unprognostic (1.60e-3)" "unprognostic (1.36e-1)" "unprognostic (2.45e-1)" "unprognostic (1.00e-2)" "unprognostic (3.54e-2)" "unprognostic (1.29e-2)" "unprognostic (4.39e-2)" "unprognostic (2.85e-2)" "unprognostic (1.52e-4)" "unprognostic (1.85e-1)" "unprognostic (8.18e-4)" "unprognostic (4.35e-2)" 0.6 0.0 0.5 0.3 0.3 0.0 2.5 0.3 0.4 6.6 0.0 0.6 0.0 0.6 0.3 0.0 0.2 1.8 0.3 0.5 0.2 6.3 0.6 0.1 0.0 0.5 0.5 0.0 2.5 0.0 1.1 56.8 0.6 0.2 0.5 3.7 0.1 0.6 0.0 0.1 0.2 0.5 0.4 0.0 1.6 0.4 0.3 0.0 0.5 0.0 0.0 0.3 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.7 0.0 0.1 0.3 0.0 0.5 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.2 4.3 2.1 3.5 0.9 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.7 0.5 0.5 0.2 0.0 0.0 0.1 0.7 0.0 0.0 0.3 1.6 1.3 0.1 0.6 0.3 0.4 0.0 19.8 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.3 0.4 0.5 0.2 0.5 0.5 0.6 0.4 0.3 0.4 0.0 0.0 0.0 26.1 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.1 0.8 0.0 0.0 5.5 0.0 1.5 0.0 0.1 11.7 0.0 2.6 0.2 0.1 0.3 140.7 0.0 16.3 0.2 71.9 0.8 0.0 0.0 0.0 0.0 0.0 0.6 1.3 0.0 10.8 0.2 0.0 0.0 0.0 1.9 11.5 0.0 0.0 2.8 0.0 41.4 0.0 5.0 37.6 0.8 0.0 10.9 0.0 0.0 0.0 0.5 0.0 2.4 6.6 0.0 1.2 1.3 2.2 0.0 0.0 74.0 0.0 0.0 0.2 0.1 PAQR4 FLJ30002 ENSG00000162073 "Progestin and adipoQ receptor family member 4" Q8N4S7 16 2969270-2973484 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 124.5;retina: 63.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 58.4;Oligodendrocytes: 62.0;Rod photoreceptor cells: 153.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "non-classical monocyte: 3.6" "Lineage enriched" "Detected in single" 9 "monocytes: 3.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA068394 Approved Vesicles NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 25: RPMI-8226 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles "HPA068394: AB_2685980" "unprognostic (1.93e-1)" "unprognostic (2.75e-1)" "unprognostic (6.73e-2)" "unprognostic (1.30e-3)" "unprognostic (8.39e-2)" "unprognostic (3.00e-2)" "prognostic unfavorable (6.86e-4)" "unprognostic (2.62e-2)" "unprognostic (7.59e-2)" "unprognostic (9.65e-3)" "unprognostic (5.21e-2)" "unprognostic (8.59e-2)" "prognostic unfavorable (3.01e-6)" "prognostic favorable (1.70e-4)" "unprognostic (1.36e-1)" "unprognostic (3.79e-2)" "unprognostic (6.06e-3)" 4.3 8.1 54.4 6.9 80.8 15.7 4.3 80.0 65.3 3.6 32.7 6.5 6.2 2.3 0.5 11.3 3.7 6.9 9.3 55.1 56.4 3.9 3.4 7.9 8.7 93.0 77.4 0.7 11.9 38.4 2.1 2.6 85.9 11.8 5.6 63.7 22.7 1.4 17.6 16.1 6.3 3.5 68.1 7.9 10.5 3.2 74.6 11.0 3.3 27.9 10.3 2.5 4.6 124.5 36.9 30.9 34.4 49.5 5.6 10.0 11.3 13.9 16.6 24.9 23.5 18.8 38.3 36.8 18.3 16.1 17.5 50.8 36.1 21.7 10.4 38.8 16.3 11.5 63.6 25.4 0.6 24.1 39.2 2.4 11.3 13.5 3.5 12.6 16.7 30.7 22.5 95.6 21.7 73.8 35.1 25.8 29.1 55.3 21.6 69.5 45.0 117.6 17.5 12.4 77.3 36.0 51.2 48.5 37.3 4.6 51.6 37.2 10.3 43.0 26.3 20.0 19.8 42.2 30.7 49.3 19.1 32.4 48.4 0.0 0.4 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 3.6 0.2 0.0 0.3 54.4 80.8 80.0 65.3 55.1 56.4 93.0 77.4 85.9 68.1 74.6 124.5 4.8 0.0 0.0 13.4 2.0 3.1 1.6 2.6 2.2 14.9 5.2 5.2 1.1 12.8 7.8 0.0 58.4 2.2 2.0 5.1 0.0 5.2 0.8 3.0 1.5 4.5 4.2 12.6 8.9 11.3 8.9 2.0 2.6 5.2 2.5 4.6 3.9 0.3 13.3 6.7 4.5 5.5 6.1 7.6 4.6 3.6 0.6 7.2 5.4 2.8 2.2 27.8 2.1 4.5 62.0 9.5 2.5 0.0 5.5 5.0 2.2 1.0 11.0 153.4 0.0 0.3 3.5 1.5 6.3 4.1 5.1 0.5 1.8 1.0 10.9 1.0 PAQR5 "FLJ20190, MPRG" ENSG00000137819 "Progestin and adipoQ receptor family member 5" Q9NXK6 15 69298912-69407780 "Predicted membrane proteins" "Differentiation, Oogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 52.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 32.9;Distal tubular cells: 46.9;Early spermatids: 38.2;granulocytes: 67.2;Late spermatids: 123.0;Proximal tubular cells: 42.3" "Cancer enhanced" "Detected in many" "renal cancer: 8.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "basophil: 1.1" "Lineage enriched" "Detected in single" 7 "granulocytes: 1.1" "Cell line enhanced" "Detected in many" "A549: 38.1;CAPAN-2: 46.4;fHDF/TERT166: 33.1;HMC-1: 79.8;U-87 MG: 33.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076729 Approved Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA076729: AB_2686813" "unprognostic (4.47e-2)" "unprognostic (3.11e-2)" "unprognostic (1.46e-1)" "unprognostic (4.05e-4)" "unprognostic (1.53e-1)" "unprognostic (8.28e-2)" "unprognostic (3.58e-3)" "unprognostic (6.12e-3)" "unprognostic (1.47e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (2.00e-1)" "prognostic favorable (1.47e-14)" "unprognostic (5.64e-2)" "unprognostic (1.73e-1)" "unprognostic (4.16e-4)" "unprognostic (4.94e-2)" 0.6 16.0 3.5 2.6 2.8 1.2 1.2 2.7 3.0 1.7 12.0 19.0 2.3 1.0 0.2 12.4 0.9 2.0 0.8 3.1 2.8 52.9 1.1 9.1 0.3 3.4 3.1 0.6 5.1 11.3 0.8 1.6 4.0 0.6 16.2 1.9 1.8 3.7 0.2 4.9 8.0 0.9 2.8 0.4 7.7 2.4 4.4 0.2 0.8 0.2 2.1 3.6 2.9 2.9 11.7 38.1 0.8 0.8 1.6 4.2 0.3 3.7 22.2 4.3 9.1 2.2 46.4 0.1 5.9 33.1 3.7 0.7 10.9 0.6 7.4 0.1 1.7 6.9 5.6 0.8 2.9 0.2 79.8 2.2 1.7 19.4 20.7 5.5 0.0 0.2 0.1 0.7 18.4 1.6 0.2 0.2 2.6 6.1 3.2 0.1 0.6 2.2 16.6 0.9 3.3 0.7 6.0 2.3 3.1 2.1 1.0 2.8 0.6 13.1 4.2 1.1 0.4 0.2 0.3 0.1 33.1 0.1 3.8 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 3.5 2.8 2.7 3.0 3.1 2.8 3.4 3.1 4.0 2.8 4.4 2.9 0.1 12.8 21.0 1.0 0.5 0.9 1.3 0.4 1.2 0.7 1.3 0.8 0.7 32.9 0.9 20.2 0.0 0.0 0.0 31.1 46.9 19.0 38.2 0.7 0.1 1.9 0.0 0.0 0.5 0.4 0.0 2.8 2.0 1.5 67.2 2.2 0.0 0.0 3.7 0.0 0.7 4.8 0.0 0.3 0.7 123.0 0.9 1.8 0.0 20.6 0.0 5.9 0.0 1.0 0.5 2.6 6.9 1.2 0.0 1.4 26.8 42.3 0.8 0.1 6.6 0.1 0.6 0.5 0.5 15.1 1.8 0.1 0.4 19.6 13.7 0.8 PARG ENSG00000227345 "Poly(ADP-ribose) glycohydrolase" Q86W56 10 49818279-49970203 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021819, HPA053007" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Vesicles, Cytosol" "HPA021819: AB_1854974, HPA053007: AB_2682014" "unprognostic (5.77e-3)" "unprognostic (6.74e-2)" "unprognostic (3.06e-2)" "unprognostic (9.90e-2)" "unprognostic (1.22e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (5.57e-5)" "unprognostic (1.21e-1)" "unprognostic (3.97e-1)" "unprognostic (8.34e-2)" "unprognostic (1.47e-1)" "unprognostic (4.06e-2)" "unprognostic (5.20e-3)" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (8.54e-2)" "unprognostic (1.13e-1)" 5.3 6.5 3.7 6.2 3.8 3.2 7.1 7.5 4.8 6.1 1.4 7.3 8.8 6.1 4.7 7.0 5.8 5.4 8.5 4.0 4.3 12.7 6.9 5.2 9.1 3.6 3.2 5.4 4.0 8.9 4.3 7.7 4.0 6.7 7.8 5.8 5.3 6.3 12.0 7.3 7.0 6.3 3.0 6.9 6.4 7.8 3.7 9.1 6.7 9.0 9.0 6.2 5.2 4.3 15.3 9.5 20.0 17.8 11.2 13.6 14.9 13.6 17.2 17.0 16.1 9.8 15.2 10.5 10.7 13.3 7.8 17.7 17.3 10.2 19.8 15.5 16.6 11.6 7.7 13.2 13.8 16.5 8.9 8.4 21.0 12.3 22.4 13.4 10.6 14.0 18.8 11.1 14.9 9.2 18.0 20.0 22.4 10.5 26.8 21.1 20.7 13.9 16.1 8.4 16.0 19.7 10.6 21.6 17.1 21.2 23.8 10.9 10.0 11.5 12.4 11.8 15.9 10.4 16.2 21.9 18.9 18.8 8.8 6.1 2.5 1.4 2.3 2.2 3.2 3.0 3.0 2.8 2.7 2.9 3.7 3.5 1.3 3.9 3.5 2.9 2.8 2.3 3.7 3.8 7.5 4.8 4.0 4.3 3.6 3.2 4.0 3.0 3.7 4.3 8.2 9.6 15.3 22.2 12.2 6.1 5.2 4.3 12.0 13.9 9.5 7.4 28.6 14.3 9.2 12.9 27.1 7.7 8.9 10.4 9.8 7.3 6.1 17.7 14.8 11.1 6.6 12.8 42.5 6.5 6.2 12.0 11.2 11.8 14.5 17.0 6.8 13.6 9.7 5.0 37.9 10.0 2.0 12.0 4.3 4.6 7.5 11.6 3.6 35.6 12.4 7.3 24.7 26.7 41.4 8.1 3.7 8.2 9.9 5.3 8.7 40.3 21.5 20.7 0.0 11.3 12.0 17.1 13.3 13.8 6.0 4.7 12.0 20.0 11.2 4.4 PARM1 "Cipar1, DKFZP564O0823, WSC4" ENSG00000169116 "Prostate androgen-regulated mucin-like protein 1" Q6UWI2 4 74933095-75050115 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 181.9;Distal enterocytes: 398.3;Intestinal goblet cells: 109.7;Paneth cells: 132.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 56.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 15 "memory B-cell: 8.1;myeloid DC: 4.0;naive B-cell: 5.6" "Group enriched" "Detected in many" 15 "B-cells: 8.1;dendritic cells: 4.0" "Cell line enhanced" "Detected in many" "ASC diff: 44.6;Karpas-707: 44.9;U-266/70: 49.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038236 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles, Cytosol" "HPA038236: AB_10675789" "unprognostic (2.57e-2)" "unprognostic (5.20e-2)" "unprognostic (1.26e-3)" "unprognostic (8.61e-2)" "unprognostic (1.44e-1)" "unprognostic (8.49e-3)" "unprognostic (3.08e-1)" "unprognostic (2.42e-2)" "unprognostic (2.73e-1)" "unprognostic (9.74e-2)" "unprognostic (9.44e-2)" "unprognostic (3.51e-2)" "unprognostic (5.21e-2)" "unprognostic (1.96e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (1.78e-4)" "unprognostic (2.23e-1)" 45.1 51.8 4.1 27.7 5.4 0.4 29.3 0.0 19.3 43.3 2.1 91.3 7.0 34.7 14.0 13.5 23.3 28.6 103.6 10.4 26.0 55.9 1.3 33.7 18.2 1.3 3.9 19.6 34.1 73.1 41.0 40.7 21.2 83.8 113.4 6.0 39.4 64.5 21.0 11.1 15.7 48.2 0.0 15.3 13.4 12.0 4.1 17.3 123.7 18.1 20.9 44.9 25.0 0.0 1.1 1.9 1.7 0.0 44.6 0.3 0.2 0.0 0.2 0.0 0.0 3.9 0.3 0.0 0.2 0.0 0.1 0.1 15.1 0.0 0.0 0.2 3.3 0.0 0.0 0.0 7.4 0.0 1.3 1.0 0.0 0.0 0.0 0.1 0.0 3.8 0.0 44.9 0.8 0.5 5.2 0.2 4.3 0.0 2.7 0.0 4.1 11.8 0.2 9.5 2.8 0.1 0.1 0.3 0.0 1.8 0.0 0.0 0.0 2.7 2.9 0.3 4.2 49.8 5.1 12.9 4.7 0.0 0.7 0.0 0.1 0.0 0.0 0.3 0.0 8.1 0.0 0.0 4.0 5.6 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.5 4.1 5.4 0.0 19.3 10.4 26.0 1.3 3.9 21.2 0.0 4.1 0.0 44.8 16.0 84.1 2.9 11.6 3.2 27.2 6.5 4.0 7.0 4.0 3.4 181.9 31.5 10.4 0.0 0.0 0.3 0.1 398.3 3.9 0.5 10.1 3.0 73.5 6.4 19.9 2.7 51.3 49.2 0.7 13.2 2.0 2.8 1.3 61.9 2.9 0.0 1.5 0.0 77.8 109.7 14.2 0.3 34.7 28.6 36.7 4.9 8.8 1.0 0.7 0.1 0.0 6.0 3.6 23.5 132.1 74.4 42.9 32.6 2.5 27.7 7.2 1.7 46.0 5.4 61.5 1.6 3.2 0.3 1.8 0.8 1.9 14.9 81.6 9.1 PAX5 BSAP ENSG00000196092 "Paired box 5" Q02548 9 36833269-37034268 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 39.7" "Cell type enriched" "Detected in some" 29 "B-cells: 91.3" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "midbrain: 6.5" "Group enriched" "Detected in some" 43 "memory B-cell: 39.0;naive B-cell: 26.0" "Lineage enriched" "Detected in single" 52 "B-cells: 39.0" "Group enriched" "Detected in some" 9 "Daudi: 66.6;REH: 194.1;U-698: 87.1" "Region enriched" "Detected in single" 11 "midbrain: 3.9" "Low region specificity" "Detected in all" "CAB026269, CAB026869, HPA056394, HPA068498" Enhanced Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" Nucleoplasm "Nucleoli fibrillar center, Vesicles, Cytosol" "CAB026269: , CAB026869: , HPA056394: AB_2683116, HPA068498: AB_2685997" "unprognostic (4.69e-4)" "unprognostic (3.83e-1)" "unprognostic (9.13e-2)" "unprognostic (1.42e-1)" "unprognostic (2.65e-2)" "unprognostic (1.15e-1)" "unprognostic (2.09e-2)" "unprognostic (2.95e-2)" "unprognostic (2.48e-1)" "unprognostic (2.00e-2)" "unprognostic (1.03e-1)" "unprognostic (2.46e-2)" "unprognostic (1.11e-3)" "unprognostic (3.15e-1)" "unprognostic (8.96e-2)" "unprognostic (6.03e-2)" "unprognostic (1.01e-1)" 0.3 0.1 0.4 14.9 0.3 9.4 0.1 0.5 0.5 0.0 0.2 0.8 0.5 0.2 0.1 0.2 0.0 0.8 0.2 0.3 0.6 0.1 0.2 0.3 39.7 1.1 6.5 0.0 0.0 0.0 0.2 0.1 4.1 0.3 0.8 0.5 1.0 0.0 3.1 0.0 6.6 0.0 0.8 18.7 1.6 0.6 1.9 2.8 0.2 0.0 36.2 1.1 0.0 0.3 0.1 0.3 5.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 66.6 0.1 0.0 0.1 0.2 0.1 0.0 0.0 3.5 0.1 0.0 0.0 0.0 0.0 2.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.5 0.1 0.3 1.9 0.3 0.4 194.1 0.4 0.3 0.0 0.0 13.2 2.9 0.1 0.7 0.0 0.0 0.0 7.5 0.2 0.0 0.2 0.1 0.0 0.2 0.1 87.1 0.0 1.5 0.1 0.7 0.0 0.1 0.0 0.1 0.1 39.0 0.0 0.0 0.1 26.0 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.7 0.4 0.3 0.5 0.5 0.3 0.6 1.1 6.5 4.1 0.8 1.9 0.3 0.0 0.0 0.0 0.7 91.3 0.0 0.3 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.4 0.6 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.5 0.1 0.0 0.3 0.0 3.1 0.0 0.9 0.0 0.0 0.2 0.5 0.0 0.0 0.3 0.0 0.1 0.0 2.7 0.4 0.0 0.1 0.0 0.1 0.0 0.8 0.1 0.6 0.2 0.2 0.0 0.0 2.0 0.0 0.0 0.3 PAXIP1 "CAGF28, CAGF29, PAXIP1L, PTIP, TNRC2" ENSG00000157212 "PAX interacting protein 1" Q6ZW49 7 154943687-155003124 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 26.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 12.0" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006694, HPA016950" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Vesicles" "HPA006694: AB_1855011, HPA016950: AB_2669489" "unprognostic (2.44e-2)" "unprognostic (1.28e-1)" "unprognostic (2.14e-2)" "unprognostic (2.66e-2)" "unprognostic (1.39e-1)" "unprognostic (1.63e-2)" "unprognostic (7.39e-3)" "unprognostic (2.65e-2)" "unprognostic (1.34e-3)" "unprognostic (1.19e-2)" "unprognostic (1.33e-1)" "unprognostic (2.36e-1)" "unprognostic (3.28e-2)" "unprognostic (4.99e-3)" "unprognostic (3.98e-1)" "unprognostic (2.44e-3)" "unprognostic (2.30e-1)" 4.3 3.9 2.3 5.8 2.5 9.8 5.4 12.0 2.6 4.8 2.7 4.9 4.8 4.6 4.8 5.4 4.2 4.4 3.9 2.3 2.4 4.6 5.7 4.2 8.8 2.8 2.6 5.7 4.4 6.2 3.8 6.1 2.9 4.4 4.9 3.9 5.7 3.6 5.9 6.5 5.7 3.7 2.5 5.6 5.2 8.7 2.6 26.6 5.5 4.6 6.0 5.3 4.7 2.8 17.7 14.2 18.4 31.2 7.8 6.5 16.4 7.6 8.0 10.3 11.9 15.7 13.6 22.9 9.4 9.1 21.3 13.6 23.7 12.1 12.7 23.0 18.4 17.4 10.7 13.6 5.5 23.9 22.3 6.3 9.0 10.3 4.2 5.8 9.9 22.8 24.3 15.1 10.4 24.3 51.1 19.9 29.8 17.1 9.5 28.8 18.7 24.8 10.7 14.6 14.6 9.4 20.3 14.9 9.5 16.6 11.4 20.1 5.1 8.6 1.5 12.3 18.6 15.2 9.5 31.0 21.1 27.7 23.6 0.2 0.9 0.5 0.9 1.1 1.4 0.5 1.5 1.1 1.0 0.9 2.4 0.7 0.5 1.3 1.3 1.2 1.2 0.9 2.3 2.5 12.0 2.6 2.3 2.4 2.8 2.6 2.9 2.5 2.6 2.8 5.2 6.4 6.3 18.9 5.8 6.4 5.1 4.7 4.0 18.9 8.9 6.6 6.9 7.2 7.1 9.2 10.4 9.0 3.8 6.8 5.9 3.9 2.3 5.5 6.9 5.2 2.4 10.3 21.4 3.3 8.0 6.9 5.6 6.5 2.5 8.8 5.0 9.2 4.4 3.3 24.2 8.4 2.0 6.1 7.1 2.8 8.7 4.8 3.6 15.9 6.3 8.0 7.2 27.2 27.4 4.4 4.3 9.4 4.9 8.0 5.2 4.2 4.3 12.3 0.0 11.1 5.1 22.6 18.7 8.9 7.0 6.2 4.9 6.3 9.8 4.5 PBLD "FLJ14767, MAWBP, MAWDBP" ENSG00000108187 "Phenazine biosynthesis like protein domain containing" P30039 10 68282660-68333049 "Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "intestine: 171.5;kidney: 270.0;liver: 335.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 97.5;Distal tubular cells: 109.5;Hepatocytes: 216.9;Proximal enterocytes: 380.2;Proximal tubular cells: 426.5" "Cancer enhanced" "Detected in all" "liver cancer: 16.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA038035, HPA038036" Enhanced Approved Vesicles NA NA 1100000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA038035: AB_10672470, HPA038036: AB_10675625" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (6.14e-2)" "unprognostic (8.83e-3)" "unprognostic (1.14e-1)" "unprognostic (2.78e-1)" "prognostic favorable (1.44e-4)" "unprognostic (8.25e-2)" "unprognostic (3.62e-2)" "unprognostic (3.36e-3)" "unprognostic (1.19e-1)" "unprognostic (6.26e-3)" "unprognostic (3.40e-2)" "unprognostic (1.17e-1)" "unprognostic (2.07e-2)" "unprognostic (8.28e-2)" "unprognostic (6.68e-2)" 8.9 11.2 2.9 8.4 5.5 9.3 4.5 5.3 5.3 3.9 4.2 33.2 171.5 5.9 3.8 3.4 7.2 9.4 6.2 3.0 4.6 270.0 335.2 3.9 5.5 4.9 4.1 3.6 63.0 5.6 2.3 4.2 4.2 5.6 27.6 8.7 4.5 5.1 5.6 5.6 146.4 5.0 3.0 4.6 54.8 3.8 4.4 2.1 5.5 3.1 2.2 5.4 2.1 8.9 3.8 7.5 7.1 4.9 6.4 3.6 3.3 15.1 9.5 5.6 5.8 6.9 9.5 4.2 5.6 10.6 2.3 5.8 3.3 3.9 4.8 2.0 5.4 3.3 9.3 6.4 3.0 5.0 3.3 6.4 4.0 3.4 4.2 10.1 3.5 4.0 3.1 9.2 8.9 5.9 4.7 8.7 2.1 3.0 3.2 8.0 9.4 7.1 11.3 5.4 4.1 5.5 10.1 5.8 7.0 2.0 20.0 5.9 10.9 5.5 3.9 2.7 2.5 5.5 4.3 6.3 6.6 2.7 1.4 2.6 2.8 1.5 0.4 1.4 0.8 0.8 0.6 0.4 2.8 0.6 1.1 0.7 3.3 1.8 0.9 1.2 1.1 1.2 2.9 5.5 5.3 5.3 3.0 4.6 4.9 4.1 4.2 3.0 4.4 8.9 1.6 3.2 4.2 3.6 4.5 1.9 1.7 2.2 1.2 5.0 6.2 2.8 3.5 24.3 4.3 55.2 10.4 3.9 3.7 97.5 109.5 8.8 1.2 17.9 5.7 3.4 7.2 6.6 1.8 31.8 2.0 3.2 33.1 6.5 1.3 8.2 6.4 216.9 3.1 10.1 2.8 42.6 2.0 10.4 4.4 0.4 4.1 5.5 1.8 3.7 5.0 5.5 3.1 3.0 7.5 12.5 46.4 3.0 1.5 2.0 380.2 426.5 12.9 17.2 0.0 2.0 6.6 1.6 1.4 1.8 0.6 3.1 2.8 9.6 57.3 3.0 PBX4 ENSG00000105717 "PBX homeobox 4" Q9BYU1 19 19561707-19618693 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 2.1;thyroid gland: 2.3" "Cell type enhanced" "Detected in many" "dendritic cells: 14.5;Gastric mucus-secreting cells: 17.3;Plasma cells: 18.8;Spermatocytes: 26.6;T-cells: 50.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 7 "gdT-cell: 1.7;MAIT T-cell: 1.7;memory CD4 T-cell: 1.2;memory CD8 T-cell: 1.9;naive CD4 T-cell: 1.2;naive CD8 T-cell: 1.0;T-reg: 3.1" "Lineage enriched" "Detected in single" 12 "T-cells: 3.1" "Cell line enhanced" "Detected in some" "A-431: 2.5;RT4: 3.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA049859, HPA056469" Enhanced Approved Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 24: Non-specific - Transcription regulation" Vesicles "HPA049859: AB_2680918, HPA056469: AB_2797256" "unprognostic (5.36e-3)" "prognostic favorable (8.69e-6)" "unprognostic (9.39e-3)" "unprognostic (1.03e-1)" "unprognostic (1.81e-2)" "unprognostic (1.07e-4)" "unprognostic (2.87e-2)" "unprognostic (1.18e-1)" "unprognostic (1.26e-1)" "unprognostic (3.86e-2)" "unprognostic (3.17e-1)" "unprognostic (1.13e-2)" "unprognostic (1.44e-6)" "unprognostic (2.20e-2)" "unprognostic (1.45e-1)" "unprognostic (5.89e-2)" "prognostic favorable (5.94e-7)" 0.2 0.0 0.6 0.4 0.6 0.4 0.2 0.3 0.8 0.1 0.3 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.6 0.6 0.1 0.0 0.3 1.2 0.5 0.5 0.2 0.0 0.1 0.3 0.2 0.5 0.1 0.1 0.0 0.1 0.1 0.0 0.4 0.4 0.0 0.4 0.3 0.4 2.1 1.0 1.0 2.3 0.0 0.6 0.1 0.1 0.5 2.5 0.1 1.0 0.0 0.2 0.0 1.7 0.0 0.8 1.1 0.8 0.0 1.1 0.3 0.4 0.6 0.9 1.1 1.4 0.0 0.3 0.1 0.5 0.0 0.4 0.0 0.1 0.0 0.4 0.2 0.0 0.3 0.0 0.0 0.0 1.5 0.0 0.0 0.3 0.5 1.0 0.7 0.2 1.8 1.9 0.5 0.0 0.0 0.8 3.2 0.8 1.1 1.1 0.1 0.8 0.1 0.4 0.1 0.0 0.0 0.5 1.5 0.3 0.2 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 1.7 0.2 1.2 1.9 0.0 0.0 1.2 1.0 0.2 0.0 0.0 0.0 3.1 0.5 0.6 0.6 0.3 0.8 0.6 0.6 0.5 0.5 0.5 0.4 1.0 0.5 0.7 0.0 4.1 9.8 8.7 4.8 2.6 1.3 1.8 0.6 1.1 1.8 0.4 1.5 1.6 0.0 0.0 0.0 14.5 1.1 1.9 0.7 3.1 8.3 1.1 0.4 0.0 0.8 5.0 0.0 1.1 3.4 17.3 3.5 0.0 1.2 0.4 0.0 0.4 0.0 7.3 2.9 0.0 0.3 3.8 1.5 0.3 1.6 1.8 1.0 1.5 1.4 6.2 1.5 1.4 2.4 0.1 0.7 18.8 2.6 0.2 0.0 5.4 0.1 6.6 1.4 1.4 26.6 10.7 0.7 2.6 0.0 50.4 0.5 0.7 3.1 PBXIP1 HPIP ENSG00000163346 "PBX homeobox interacting protein 1" Q96AQ6 1 154944076-154956123 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 176.0;Muller glia cells: 221.4;Theca cells: 153.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "granulocytes: 183.9;NK-cells: 56.9;T-cells: 197.4" "Cell line enriched" "Detected in all" 7 "Karpas-707: 1100.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006949 Approved Approved Vesicles,Cytosol NA NA 26000 "Cluster 13: T-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Vesicles Cytosol "HPA006949: AB_1079572" "unprognostic (6.17e-2)" "unprognostic (6.82e-2)" "prognostic unfavorable (2.73e-4)" "unprognostic (8.94e-2)" "unprognostic (2.16e-1)" "prognostic favorable (7.19e-4)" "unprognostic (1.62e-1)" "prognostic favorable (8.99e-4)" "unprognostic (1.21e-1)" "unprognostic (2.46e-1)" "prognostic favorable (2.64e-4)" "unprognostic (1.20e-2)" "prognostic favorable (9.22e-6)" "unprognostic (3.89e-1)" "unprognostic (4.15e-1)" "unprognostic (2.26e-1)" "unprognostic (1.26e-3)" 57.7 122.5 169.3 58.4 180.3 35.1 45.9 159.8 158.8 74.5 296.1 124.5 55.4 81.7 39.0 46.0 68.8 52.8 67.7 144.4 173.6 56.9 29.7 49.0 69.4 208.2 189.7 115.3 34.0 102.4 168.9 33.3 168.5 63.6 29.7 38.9 53.0 95.3 139.7 37.2 90.7 52.4 171.7 82.2 82.7 58.1 210.4 80.8 85.9 100.5 59.1 79.2 50.5 161.2 7.3 19.1 29.9 20.0 101.3 31.5 22.0 25.1 55.3 11.9 23.5 5.6 24.9 31.3 79.1 30.5 17.0 26.8 7.3 16.1 8.3 16.9 11.7 7.1 26.2 20.1 46.9 8.6 83.6 48.0 26.2 15.1 3.0 137.7 45.4 23.6 4.2 1100.7 29.8 11.1 17.6 27.5 11.4 19.3 14.4 20.2 43.1 69.7 32.9 14.1 4.9 37.6 32.5 10.2 26.7 56.1 31.0 36.6 42.9 11.8 8.6 7.6 7.8 149.4 133.9 7.7 42.2 12.4 9.6 129.4 10.3 183.9 41.9 14.8 116.3 36.0 112.4 66.9 9.1 23.6 72.9 46.2 95.2 56.9 29.7 16.2 197.4 61.5 169.3 180.3 159.8 158.8 144.4 173.6 208.2 189.7 168.5 171.7 210.4 161.2 24.5 67.3 77.9 56.8 43.0 10.1 24.0 22.4 13.1 23.8 17.6 19.7 38.5 38.6 31.1 42.3 16.7 19.5 48.2 21.0 0.0 46.0 142.1 12.9 25.9 23.8 83.7 22.3 1.5 18.5 24.0 35.9 19.9 10.5 51.9 30.3 28.9 19.4 14.7 1.7 1.2 20.9 69.2 20.2 13.8 176.0 64.3 16.8 26.6 7.5 25.5 221.4 39.1 3.5 1.6 22.4 29.3 129.1 49.0 10.5 56.0 9.9 23.9 8.8 52.6 83.9 50.6 8.8 13.9 6.3 11.5 27.1 116.2 153.3 15.9 13.9 PCBP3 "FLJ44028, PCBP3-OT1, PCBP3OT" ENSG00000183570 "Poly(rC) binding protein 3" P57721 21 45643694-45942454 "Plasma proteins, Predicted intracellular proteins" "DNA-binding, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.6;retina: 81.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 159.4;Cone photoreceptor cells: 50.1;Horizontal cells: 116.1;Late spermatids: 79.8;Muller glia cells: 49.3;Rod photoreceptor cells: 83.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 29.0;HDLM-2: 56.9;HSkMC: 40.8;SH-SY5Y: 46.9;U-87 MG: 25.0;U-937: 31.3" "Region enriched" "Detected in all" 5 "olfactory bulb: 229.1" "HPA030247, HPA073145" Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 46: Basophils - DNA binding" "Cluster 77: Retina - Visual perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Mitochondria" Vesicles "HPA030247: AB_10601244, HPA073145: " "unprognostic (3.88e-2)" "unprognostic (1.19e-1)" "unprognostic (2.01e-4)" "unprognostic (9.89e-4)" "unprognostic (2.74e-1)" "unprognostic (1.40e-1)" "unprognostic (4.10e-2)" "unprognostic (2.42e-1)" "unprognostic (3.87e-2)" "unprognostic (1.64e-3)" "unprognostic (1.12e-3)" "unprognostic (1.97e-2)" "unprognostic (1.96e-6)" "unprognostic (8.67e-2)" "unprognostic (2.32e-2)" "unprognostic (8.04e-2)" "unprognostic (1.97e-2)" 7.3 7.1 8.9 7.5 6.8 8.9 4.5 34.6 11.9 8.2 2.8 13.7 1.7 8.7 7.5 1.4 5.3 2.6 3.4 13.5 8.1 4.8 1.3 2.8 3.3 32.3 12.0 3.9 2.7 0.1 22.6 1.2 31.3 2.3 1.6 81.5 1.8 0.8 0.4 2.1 8.7 7.8 8.9 10.0 4.7 14.8 17.9 18.9 1.0 1.7 2.9 4.1 2.8 9.5 0.0 0.0 0.5 0.0 13.7 29.0 0.2 1.8 0.4 3.1 1.4 0.0 0.0 0.0 0.7 8.2 3.9 0.1 1.7 0.0 0.5 56.9 0.2 0.0 0.0 0.0 13.7 0.0 0.0 40.8 0.2 0.5 0.8 0.0 0.0 2.0 0.0 0.2 1.8 0.7 16.5 3.3 0.8 0.1 2.8 0.0 0.1 2.4 0.0 0.0 4.9 46.9 1.2 0.0 0.0 1.3 0.0 8.7 0.0 0.0 0.1 12.3 0.0 0.7 3.1 0.0 25.0 31.3 1.1 2.1 0.2 3.0 0.7 0.1 0.1 1.3 0.4 0.0 0.0 1.4 0.7 0.1 0.7 0.3 0.1 0.0 0.4 0.2 8.9 6.8 34.6 11.9 13.5 8.1 32.3 12.0 31.3 8.9 17.9 9.5 0.6 0.0 0.0 2.3 6.2 0.3 0.1 0.3 0.0 159.4 0.1 0.5 3.6 0.0 0.7 1.8 50.1 0.1 0.3 0.0 0.0 0.1 36.5 0.2 8.9 2.2 3.0 0.0 3.8 0.2 0.1 2.3 0.5 0.3 0.0 0.2 2.2 0.0 0.4 116.1 4.6 0.1 0.0 0.0 0.7 79.8 8.4 0.9 3.6 1.0 0.0 49.3 0.0 0.5 5.5 0.9 0.1 12.8 4.1 1.3 0.0 0.4 0.0 83.1 0.0 1.1 3.9 34.1 21.2 0.0 0.0 0.0 2.5 0.2 0.2 0.5 PCDH10 "KIAA1400, OL-PCDH" ENSG00000138650 "Protocadherin 10" Q9P2E7 4 133149294-133208606 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 35.4;placenta: 25.9;prostate: 10.6;seminal vesicle: 17.3" "Cell type enhanced" "Detected in many" "Astrocytes: 58.1;Endometrial ciliated cells: 26.5;Excitatory neurons: 64.9;Glandular and luminal cells: 29.1;Inhibitory neurons: 57.7;Oligodendrocyte precursor cells: 46.8;Oligodendrocytes: 59.6" "Cancer enhanced" "Detected in many" "glioma: 8.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 11.5;HUVEC TERT2: 27.4;MOLT-4: 24.1;TIME: 55.4;U-138 MG: 14.5;U-251 MG: 12.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011220, HPA073462" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" No NA 88000 "Cluster 65: Brain - Ion transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA011220: AB_1855041, HPA073462: AB_2686605" "unprognostic (7.20e-2)" "unprognostic (8.74e-3)" "unprognostic (4.30e-2)" "unprognostic (8.12e-5)" "unprognostic (8.33e-2)" "unprognostic (3.20e-1)" "unprognostic (5.27e-3)" "unprognostic (4.51e-1)" "unprognostic (3.83e-2)" "unprognostic (1.15e-1)" "unprognostic (9.30e-3)" "unprognostic (8.72e-2)" "unprognostic (1.45e-1)" "unprognostic (8.68e-4)" "unprognostic (8.88e-2)" "unprognostic (6.31e-2)" "unprognostic (2.16e-4)" 0.5 5.1 20.5 0.2 35.4 0.0 0.1 0.9 23.9 1.5 0.0 0.5 0.1 1.6 0.5 0.3 1.2 0.5 1.2 19.6 15.2 2.1 0.1 0.7 0.0 7.7 24.9 2.3 0.2 0.0 1.4 25.9 11.3 10.6 0.2 3.0 0.5 17.3 0.0 0.0 0.4 0.7 3.7 0.0 0.4 1.4 16.8 0.1 0.5 0.0 0.0 1.8 2.8 19.1 0.0 0.7 8.7 0.0 0.3 0.0 0.0 8.6 4.6 0.7 0.4 0.0 0.0 0.0 0.2 0.3 0.2 0.0 0.0 0.0 0.9 0.0 4.9 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 11.5 27.4 0.0 0.3 0.0 4.2 0.0 24.1 0.0 0.0 0.0 0.3 0.5 0.3 0.5 0.0 0.4 0.0 0.2 0.0 0.0 0.1 0.5 0.0 0.3 55.4 14.5 0.0 0.1 12.9 0.0 0.0 0.0 1.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.5 35.4 0.9 23.9 19.6 15.2 7.7 24.9 11.3 3.7 16.8 19.1 1.4 0.0 0.6 58.1 0.0 0.1 0.5 0.1 1.2 15.0 1.2 2.7 2.3 0.0 0.7 0.0 0.0 0.8 0.0 0.9 1.9 0.0 5.6 26.5 4.6 4.0 0.0 0.0 64.9 0.0 0.9 15.5 0.0 29.1 0.0 5.0 0.0 0.0 1.8 0.0 57.7 0.2 0.0 0.0 0.0 1.7 0.0 0.5 0.0 6.5 0.0 8.6 0.0 46.8 59.6 0.0 0.0 0.4 0.0 0.1 0.0 0.3 0.1 2.7 0.0 4.3 11.5 17.4 0.9 0.0 0.3 2.9 0.2 3.9 0.1 0.4 PCDH17 "PCDH68, PCH68" ENSG00000118946 "Protocadherin 17" O14917 13 57631744-57729311 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.9;lymphoid tissue: 25.1" "Group enriched" "Detected in many" 4 "Adipocytes: 57.6;Astrocytes: 77.1;Early spermatids: 60.7;Endothelial cells: 126.7;Excitatory neurons: 125.2;Hepatic stellate cells: 79.6;Inhibitory neurons: 67.9;Oligodendrocyte precursor cells: 193.0;Oligodendrocytes: 101.1;Spermatocytes: 68.3" "Cancer enhanced" "Detected in many" "glioma: 9.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.7;HEK 293: 9.3;U-87 MG: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026817 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA 690000 "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" "Plasma membrane" "HPA026817: AB_1855044" "unprognostic (1.02e-2)" "unprognostic (2.39e-1)" "unprognostic (1.19e-1)" "unprognostic (6.52e-2)" "unprognostic (6.98e-3)" "unprognostic (1.95e-2)" "unprognostic (8.26e-4)" "unprognostic (3.56e-1)" "unprognostic (2.38e-2)" "unprognostic (2.82e-1)" "unprognostic (5.40e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (1.07e-2)" "unprognostic (1.80e-1)" "unprognostic (2.35e-1)" "unprognostic (3.40e-2)" 1.6 1.8 15.8 1.8 20.6 0.0 0.8 7.9 13.9 2.2 0.1 1.2 0.8 2.1 0.8 0.6 2.0 3.2 2.2 11.7 25.5 1.9 1.0 14.0 0.6 9.3 15.8 0.5 6.0 1.6 0.9 4.4 11.4 1.0 0.8 1.0 0.7 0.7 1.7 0.3 0.8 2.1 7.6 25.1 1.5 8.8 27.9 0.2 2.9 1.3 0.5 2.7 0.8 10.5 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 2.5 0.0 0.0 0.0 1.7 0.0 0.0 0.0 9.3 0.4 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.3 0.0 2.3 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.4 1.2 0.0 1.0 0.0 0.0 0.0 5.3 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 20.6 7.9 13.9 11.7 25.5 9.3 15.8 11.4 7.6 27.9 10.5 57.6 0.0 4.3 77.1 0.1 2.7 0.1 0.0 1.2 7.1 0.4 0.6 6.0 1.5 8.6 1.8 0.0 0.2 0.5 0.1 0.0 11.1 60.7 2.6 2.0 126.7 0.0 0.0 125.2 8.3 0.1 11.7 0.0 19.8 0.0 20.5 79.6 0.3 0.6 0.0 67.9 0.0 0.0 1.9 2.5 19.0 1.8 0.5 10.6 12.2 1.6 2.3 0.0 193.0 101.1 1.3 0.0 1.2 1.2 0.3 0.0 0.0 5.1 0.0 6.6 1.9 10.7 68.3 10.6 0.4 1.0 0.0 1.1 1.6 0.0 0.4 PCDH20 "FLJ22218, PCDH13" ENSG00000280165 "Protocadherin 20" Q8N6Y1 13 61409685-61415522 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.0;smooth muscle: 9.0" "Cell type enhanced" "Detected in some" "Club cells: 6.2;Excitatory neurons: 8.2;Inhibitory neurons: 7.9;Intestinal goblet cells: 5.3;Ionocytes: 6.1;Oligodendrocyte precursor cells: 32.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 14 "RPTEC TERT1: 51.3" HPA062669 Approved "Vesicles,Cytokinetic bridge" Yes NA "Cluster 10: Brain - Neuronal signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 68: Oligodendrocytes - Mixed function" Vesicles "Cytokinetic bridge" "HPA062669: AB_2732687" "unprognostic (2.40e-1)" "unprognostic (1.80e-1)" "unprognostic (2.45e-1)" "unprognostic (7.83e-2)" "unprognostic (6.79e-4)" "unprognostic (2.32e-2)" "unprognostic (1.56e-1)" "unprognostic (5.34e-4)" "unprognostic (6.96e-2)" "unprognostic (1.67e-1)" "unprognostic (3.12e-1)" 0.5 1.1 3.0 0.3 4.4 0.0 0.9 1.0 11.2 2.3 0.0 3.1 0.9 3.1 2.6 0.7 0.5 0.6 3.5 18.0 3.7 0.8 1.3 3.3 0.0 1.5 4.6 0.3 0.1 0.0 0.5 0.4 1.3 1.0 1.7 0.0 0.7 1.0 0.4 1.0 1.0 9.0 2.3 1.2 1.0 0.1 2.8 0.8 0.2 0.7 0.0 0.6 0.5 2.3 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.0 0.0 51.3 0.0 0.7 1.9 0.0 3.6 0.5 0.1 1.0 0.1 0.0 0.0 0.0 0.0 0.4 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 4.4 1.0 11.2 18.0 3.7 1.5 4.6 1.3 2.3 2.8 2.3 0.0 3.2 0.5 2.3 0.0 0.1 0.1 3.6 0.0 0.0 0.0 0.0 0.6 0.0 6.2 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 8.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 7.9 5.3 6.1 0.0 0.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 32.6 1.0 0.1 2.3 0.0 0.0 0.1 0.0 0.0 2.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.2 PCDHA11 "CNR7, CNRN7, CNRS7, CRNR7, PCDH-ALPHA11" ENSG00000249158 "Protocadherin alpha 11" Q9Y5I1 5 140868183-141012347 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.2;parathyroid gland: 2.7;retina: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.0;AN3-CA: 10.7;EFO-21: 7.6;MCF7: 4.4;T-47d: 6.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA077160 Approved "Vesicles,Cell Junctions,Cytoplasmic bodies" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Cell Junctions" "Cytoplasmic bodies" "HPA077160: AB_2686827" "unprognostic (1.54e-2)" "unprognostic (1.83e-3)" "unprognostic (2.75e-1)" "unprognostic (2.59e-1)" "unprognostic (6.98e-3)" "unprognostic (1.36e-1)" "unprognostic (9.28e-3)" "unprognostic (2.40e-3)" "unprognostic (2.53e-2)" "unprognostic (1.53e-2)" "unprognostic (2.27e-2)" "unprognostic (3.13e-4)" "unprognostic (9.91e-5)" "unprognostic (1.05e-1)" "unprognostic (3.85e-3)" "unprognostic (3.26e-2)" 0.2 0.3 1.5 0.1 1.3 0.0 0.2 4.2 2.2 0.8 0.0 0.1 0.0 0.5 0.1 0.0 0.2 0.8 0.0 1.1 0.3 0.7 0.1 0.4 0.1 0.0 1.5 0.0 1.8 2.7 1.0 0.0 0.3 0.1 0.0 2.4 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 1.0 0.2 0.0 0.8 0.0 0.0 0.1 0.0 0.7 0.0 2.1 4.0 10.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 7.6 0.0 0.8 0.0 0.1 1.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.4 0.3 0.0 1.0 0.0 0.1 0.0 4.4 0.0 0.0 3.5 0.8 2.8 0.0 0.0 0.0 0.4 1.6 0.2 1.9 0.0 1.9 0.4 1.9 6.5 0.0 0.0 0.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.3 4.2 2.2 1.1 0.3 0.0 1.5 0.3 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDHA6 "CNR2, CNRS2, CRNR2, PCDH-ALPHA6" ENSG00000081842 "Protocadherin alpha 6" Q9UN73 5 140827958-141012347 "Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.0;EFO-21: 8.4;hTERT-RPE1: 2.2;U-2 OS: 3.4;WM-115: 5.2" "Low region specificity" "Detected in many" "HPA059326, HPA078110" Enhanced Approved Vesicles "Secreted in brain" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 38: EFO-21 - Unknown function" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA059326: AB_2683980, HPA078110: AB_2732371" "unprognostic (1.15e-1)" "unprognostic (7.00e-2)" "unprognostic (5.07e-1)" "unprognostic (2.79e-1)" "unprognostic (4.39e-1)" "unprognostic (1.86e-1)" "unprognostic (7.18e-4)" "unprognostic (4.23e-3)" "unprognostic (8.38e-2)" "unprognostic (2.55e-1)" "unprognostic (1.23e-3)" "unprognostic (3.44e-1)" "unprognostic (1.03e-2)" "unprognostic (2.66e-3)" "unprognostic (2.56e-1)" "unprognostic (5.66e-3)" "unprognostic (3.55e-2)" 0.2 0.3 0.8 0.1 0.9 0.0 0.3 4.1 1.1 0.4 0.0 0.1 0.2 0.6 0.3 0.0 0.3 0.3 0.1 1.0 0.7 0.4 0.0 0.2 0.1 0.4 0.3 0.4 1.0 1.5 1.5 0.0 0.5 0.2 0.0 1.1 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.0 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.9 0.0 0.1 2.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 1.5 1.0 0.1 0.4 0.0 1.3 0.0 3.4 0.2 0.0 0.0 0.1 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 4.1 1.1 1.0 0.7 0.4 0.3 0.5 0.1 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDHAC1 ENSG00000248383 "Protocadherin alpha subfamily C, 1" Q9H158 5 140926299-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "parathyroid gland: 29.8" "Cell type enriched" "Detected in some" 4 "Alveolar cells type 1: 6.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 5.7;EFO-21: 2.5;hTCEpi: 5.9;PC-3: 4.2;SCLC-21H: 2.9" "Low region specificity" "Detected in all" HPA052775 Approved Nucleoplasm,Nucleoli,Vesicles No No "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Nucleoli" Vesicles "HPA052775: AB_2681942" "unprognostic (2.52e-1)" "unprognostic (1.06e-1)" "unprognostic (3.32e-3)" "unprognostic (9.52e-3)" "unprognostic (1.36e-1)" "unprognostic (9.63e-2)" "unprognostic (4.27e-2)" "unprognostic (2.51e-2)" "unprognostic (1.17e-1)" "unprognostic (6.24e-2)" "unprognostic (2.09e-1)" "unprognostic (3.64e-3)" "unprognostic (1.04e-3)" "unprognostic (3.25e-3)" "unprognostic (1.35e-1)" "unprognostic (2.96e-1)" "unprognostic (3.29e-2)" 0.4 0.4 0.6 0.5 0.7 0.0 0.1 4.5 1.0 0.4 0.0 0.1 0.0 0.1 0.1 0.0 0.1 1.0 0.0 0.5 0.5 0.2 0.1 0.7 1.2 2.0 3.1 0.0 1.2 29.8 0.7 0.0 2.3 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.7 0.7 0.0 0.9 0.0 0.6 0.0 0.0 0.6 0.0 5.7 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.7 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 4.2 0.0 0.0 0.0 0.1 0.3 2.9 1.7 0.0 0.4 0.0 0.5 0.3 0.0 0.0 0.3 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 4.5 1.0 0.5 0.5 2.0 3.1 2.3 0.0 0.7 0.6 0.1 6.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 1.2 0.0 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDHB14 PCDH-BETA14 ENSG00000120327 "Protocadherin beta 14" Q9Y5E9 5 141223343-141227759 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 15.1;Early spermatids: 8.1;Horizontal cells: 13.5;Peritubular cells: 8.6;Spermatocytes: 8.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SH-SY5Y: 14.4;SiHa: 12.0;U-2197: 8.5" "Low region specificity" "Detected in all" "HPA007692, HPA045248" Uncertain Approved Vesicles NA NA 39000 "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA007692: AB_2667896, HPA045248: AB_10959599" "unprognostic (2.57e-3)" "unprognostic (1.96e-1)" "unprognostic (1.34e-1)" "unprognostic (8.97e-2)" "unprognostic (2.03e-2)" "unprognostic (6.64e-2)" "unprognostic (2.11e-2)" "unprognostic (2.38e-2)" "unprognostic (6.60e-2)" "unprognostic (2.57e-2)" "unprognostic (1.13e-1)" "unprognostic (2.07e-2)" "prognostic unfavorable (6.09e-4)" "unprognostic (2.58e-1)" "unprognostic (3.12e-2)" "unprognostic (3.77e-2)" "unprognostic (3.90e-2)" 3.1 2.8 2.3 0.8 3.2 0.1 3.5 2.1 4.0 6.0 0.0 4.6 0.3 7.0 2.4 2.0 4.3 1.9 4.4 2.6 1.3 2.1 1.2 3.0 0.4 1.5 2.3 4.7 4.0 3.6 6.2 1.1 0.7 3.1 0.9 2.3 3.6 1.9 1.6 4.4 1.6 2.6 1.6 2.0 1.9 2.5 3.1 0.4 2.2 1.5 0.3 3.5 3.5 3.3 0.0 0.0 3.3 6.3 5.4 6.4 0.4 0.5 5.5 0.5 1.7 0.1 1.0 0.3 4.5 1.5 2.9 0.3 0.7 1.0 0.5 0.0 0.1 0.0 1.3 0.1 0.2 0.3 0.2 1.2 4.7 0.1 0.2 4.8 0.6 0.2 0.0 5.8 2.3 0.5 0.4 0.0 0.4 0.0 1.1 3.8 4.1 0.0 0.1 0.2 7.6 14.4 12.0 0.3 1.3 0.5 6.1 0.5 1.7 2.2 1.9 8.5 2.2 0.0 0.1 0.1 4.5 0.1 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.2 2.1 4.0 2.6 1.3 1.5 2.3 0.7 1.6 3.1 3.3 4.1 0.0 4.8 0.0 0.0 0.4 1.1 3.1 0.0 15.1 1.6 2.4 3.3 0.0 3.1 1.8 0.0 0.0 0.2 0.3 0.0 0.9 8.1 0.8 6.3 3.9 3.5 0.0 0.0 2.4 0.0 5.0 0.0 0.9 0.0 1.3 3.3 1.3 0.1 13.5 0.0 0.6 4.1 0.0 0.7 2.1 3.4 0.3 0.0 0.0 0.0 6.8 0.0 0.0 0.0 2.2 0.5 8.6 0.0 0.5 0.0 0.8 0.6 1.3 0.0 6.3 3.9 8.0 0.1 0.7 2.8 0.0 0.2 2.5 0.3 0.7 PCDHB16 "KIAA1621, ME1, PCDH-BETA16, PCDH3X, PCDHB8a" ENSG00000272674 "Protocadherin beta 16" Q9NRJ7 5 141182387-141186226 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 14.9;Endometrial stromal cells: 10.0;Fibroblasts: 7.3;Horizontal cells: 8.4;Skeletal myocytes: 7.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 19.4;LHCN-M2: 10.5;U-138 MG: 39.3;U-2197: 11.1;U-87 MG: 9.9" "Low region specificity" "Detected in all" HPA014668 Approved "Vesicles,Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA014668: AB_1855055" "unprognostic (3.44e-3)" "unprognostic (4.03e-2)" "unprognostic (8.14e-2)" "unprognostic (8.60e-2)" "unprognostic (2.78e-2)" "unprognostic (1.36e-2)" "unprognostic (1.17e-1)" "unprognostic (4.03e-2)" "unprognostic (3.13e-2)" "unprognostic (7.55e-3)" "unprognostic (3.49e-2)" "unprognostic (9.57e-2)" "unprognostic (3.55e-2)" "unprognostic (7.49e-3)" "unprognostic (2.00e-2)" "unprognostic (7.92e-3)" "unprognostic (2.83e-3)" 3.1 1.9 1.2 1.2 0.9 0.2 2.4 2.1 1.8 2.6 0.0 1.6 0.5 4.5 4.8 0.7 2.2 2.0 2.5 1.6 0.8 2.0 1.0 2.4 0.6 2.0 1.0 6.7 1.9 4.3 2.3 1.2 1.2 1.7 0.9 2.2 1.8 0.9 1.0 1.3 0.9 2.7 1.5 1.1 0.9 1.4 1.3 0.4 1.7 3.3 0.2 1.6 1.5 2.2 0.1 0.3 1.0 19.4 7.8 5.2 0.6 0.8 3.8 0.0 0.3 0.1 0.3 0.0 5.0 0.9 2.1 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.4 0.4 0.0 0.1 0.2 0.1 0.1 0.0 0.0 3.3 0.1 0.2 0.1 2.0 10.5 0.4 0.0 0.1 1.5 0.0 0.2 0.1 2.8 0.0 0.6 0.2 0.7 2.6 0.3 0.6 3.9 0.5 7.9 0.0 0.6 39.3 1.7 11.1 2.7 0.1 0.1 0.0 9.9 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 1.2 0.9 2.1 1.8 1.6 0.8 2.0 1.0 1.2 1.5 1.3 2.2 6.4 3.2 1.5 0.0 0.0 0.8 0.1 1.0 0.0 14.9 1.2 2.4 1.9 5.7 0.6 1.8 0.0 0.0 0.0 0.0 1.9 0.8 1.2 0.6 10.0 4.8 1.8 0.0 0.0 4.7 0.0 7.3 0.5 0.4 0.0 0.2 2.2 0.1 0.1 8.4 0.0 0.0 4.1 0.3 0.9 1.5 4.7 0.2 0.0 0.0 0.0 5.4 0.0 0.0 0.0 1.7 0.0 5.7 0.1 0.1 0.0 0.7 0.2 1.6 0.0 7.6 5.9 2.9 0.3 0.5 1.4 0.0 0.2 0.4 0.0 0.0 PCDHB3 PCDH-BETA3 ENSG00000113205 "Protocadherin beta 3" Q9Y5E6 5 141100473-141103827 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 2.8;Cone photoreceptor cells: 2.1;Endometrial stromal cells: 2.6;Horizontal cells: 8.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 11.3;HAP1: 3.5;SH-SY5Y: 15.2;U-138 MG: 5.3" "Low region specificity" "Detected in all" HPA050296 Uncertain Supported Vesicles NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA050296: AB_2681078" "unprognostic (2.72e-2)" "unprognostic (7.47e-4)" "unprognostic (1.22e-1)" "unprognostic (1.95e-4)" "unprognostic (9.34e-3)" "unprognostic (3.42e-2)" "unprognostic (2.29e-2)" "unprognostic (3.17e-1)" "unprognostic (1.37e-1)" "unprognostic (3.34e-1)" "unprognostic (8.52e-3)" "unprognostic (3.45e-2)" "unprognostic (1.82e-2)" "unprognostic (2.37e-3)" "unprognostic (1.24e-1)" "unprognostic (1.82e-2)" "unprognostic (5.18e-4)" 1.8 1.2 0.4 0.7 1.1 0.0 1.7 0.6 1.5 1.2 0.0 0.9 0.3 1.5 0.7 0.3 0.9 0.8 1.1 1.0 0.2 1.1 0.1 1.1 0.1 0.3 0.5 1.6 1.2 1.7 1.8 0.4 0.1 1.4 0.5 1.0 0.7 0.5 0.7 0.7 0.5 1.0 0.2 0.4 0.5 3.6 0.6 0.0 0.7 0.9 0.1 0.8 0.9 0.8 0.0 0.0 1.1 3.1 1.9 0.3 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 11.3 0.2 1.7 0.0 3.5 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 1.3 0.0 0.5 0.0 0.2 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.6 15.2 0.0 0.1 0.0 0.5 1.9 0.1 0.0 5.3 0.7 0.5 0.3 0.3 0.0 0.0 0.3 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.1 0.6 1.5 1.0 0.2 0.3 0.5 0.1 0.2 0.6 0.8 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.9 0.8 0.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.9 0.3 0.8 0.4 2.6 1.1 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.2 0.0 0.0 1.8 0.0 0.0 8.4 0.0 0.2 0.0 0.0 0.3 0.0 0.6 0.0 1.8 0.0 0.0 0.9 0.0 0.0 0.0 0.3 0.0 0.7 0.0 0.5 0.0 0.1 0.0 0.3 0.0 1.7 1.1 1.8 0.7 0.1 0.3 0.0 0.0 0.4 0.0 0.3 PCDHB5 "DKFZp586B0217, PCDH-BETA5" ENSG00000113209 "Protocadherin beta 5" Q9Y5E4 5 141135206-141138615 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 5.2;Early spermatids: 8.2;Muller glia cells: 5.0;Spermatocytes: 13.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 18.7;GAMG: 13.9;NTERA-2: 17.7;RH-30: 14.0;SCLC-21H: 16.4;SuSa: 21.7;T-47d: 17.6;U-138 MG: 32.4;U-2 OS: 14.1;WM-115: 14.7" "Low region specificity" "Detected in many" "HPA013191, HPA067473" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" Vesicles "HPA013191: AB_1855059, HPA067473: " "unprognostic (2.21e-1)" "unprognostic (4.71e-2)" "unprognostic (4.05e-3)" "unprognostic (1.81e-1)" "unprognostic (2.84e-2)" "unprognostic (5.23e-2)" "unprognostic (2.27e-2)" "unprognostic (1.76e-1)" "unprognostic (9.41e-2)" "unprognostic (1.25e-1)" "unprognostic (1.32e-2)" "unprognostic (3.16e-1)" "unprognostic (1.32e-1)" "unprognostic (1.06e-3)" "unprognostic (6.65e-2)" "unprognostic (3.14e-2)" "unprognostic (1.55e-3)" 1.4 1.6 2.2 0.4 1.7 0.0 1.6 1.1 3.2 3.4 0.0 1.4 0.2 4.2 3.5 0.7 2.8 1.8 1.9 2.8 0.6 2.4 0.7 1.7 0.2 2.5 1.6 5.9 4.7 2.7 3.2 0.4 1.3 2.9 0.3 2.4 2.2 2.1 1.1 0.6 0.6 2.1 1.7 0.7 1.0 3.1 1.8 0.4 2.5 0.6 0.1 1.6 1.3 2.3 0.0 1.0 18.7 0.3 1.3 0.8 0.2 0.4 0.1 0.3 0.3 0.0 0.0 0.0 9.6 0.0 13.9 0.0 9.8 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.3 0.0 1.0 0.7 0.0 0.0 0.1 3.8 0.9 0.0 0.7 0.1 0.0 0.0 0.1 0.0 17.7 0.0 0.0 0.0 14.0 0.0 0.0 0.0 16.4 0.5 0.0 0.2 6.1 21.7 17.6 4.3 0.0 32.4 14.1 5.3 0.0 0.0 0.0 0.0 1.7 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.7 1.1 3.2 2.8 0.6 2.5 1.6 1.3 1.7 1.8 2.3 1.9 0.0 0.0 0.0 0.0 0.0 1.5 0.8 0.6 5.2 0.9 2.2 1.1 1.5 1.8 1.8 0.0 0.0 0.0 0.0 0.0 2.5 8.2 0.5 4.3 1.1 0.0 0.0 0.0 3.6 0.0 1.5 0.0 0.2 0.0 0.5 0.4 0.4 0.0 3.3 0.0 0.0 0.0 0.0 0.0 3.8 3.1 0.1 0.0 0.0 0.0 5.0 0.0 0.0 0.0 2.2 0.0 4.5 0.0 1.1 0.0 0.5 0.1 0.7 0.0 2.1 2.7 13.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.6 PCDHGA1 PCDH-GAMMA-A1 ENSG00000204956 "Protocadherin gamma subfamily A, 1" Q9Y5H4 5 141330571-141512981 "Predicted membrane proteins" "Cell adhesion" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Bipolar cells: 2.4;Cardiomyocytes: 1.8;Horizontal cells: 3.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "LHCN-M2: 4.5;T-47d: 7.3;WM-115: 3.3" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA036547" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 6: T47d - Mammary gland" "Cluster 37: Myocytes - Muscle contraction" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA036547: AB_10669798" "unprognostic (9.50e-4)" "unprognostic (2.39e-2)" "unprognostic (9.88e-2)" "unprognostic (4.42e-3)" "unprognostic (3.39e-1)" "unprognostic (3.97e-2)" "unprognostic (2.42e-1)" "unprognostic (5.61e-3)" "unprognostic (1.70e-2)" "unprognostic (6.89e-2)" "unprognostic (2.86e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-3)" "unprognostic (4.76e-2)" "unprognostic (1.38e-1)" "unprognostic (2.73e-2)" "unprognostic (1.45e-3)" 0.3 0.2 1.1 0.2 2.3 0.2 0.2 3.2 2.0 0.5 0.0 0.5 0.2 0.6 0.9 0.2 0.4 0.1 1.2 2.2 0.9 0.2 0.1 0.3 0.1 1.5 1.4 0.6 0.5 0.5 0.9 0.5 0.9 0.3 0.2 1.0 0.2 0.2 0.7 0.3 0.1 0.4 1.7 0.2 0.1 0.7 1.4 0.1 0.2 0.4 0.1 0.4 0.3 1.3 0.0 0.2 0.3 1.1 0.7 1.3 0.1 1.1 0.7 0.3 0.6 0.3 0.1 0.2 1.8 0.7 0.5 0.1 0.1 0.2 0.7 0.1 0.1 0.1 0.2 0.1 0.2 0.0 0.1 1.1 0.3 0.0 0.4 2.1 0.0 0.1 0.1 0.5 4.5 0.0 0.1 0.5 0.1 0.0 0.2 2.0 1.6 0.2 0.2 0.2 1.0 1.3 0.1 0.6 1.1 0.3 7.3 0.2 0.5 2.0 0.3 1.0 0.2 0.1 0.6 0.1 2.4 0.1 3.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.1 2.3 3.2 2.0 2.2 0.9 1.5 1.4 0.9 1.7 1.4 1.3 0.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.7 0.3 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 PCDHGA10 PCDH-GAMMA-A10 ENSG00000253846 "Protocadherin gamma subfamily A, 10" Q9Y5H3 5 141412987-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 27.7;Cone photoreceptor cells: 16.7;Horizontal cells: 23.5;Skeletal myocytes: 14.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 14.6;HSkMC: 16.1;T-47d: 19.7;U-2197: 11.6" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077276" Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 6: T47d - Mammary gland" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077276: " "unprognostic (2.92e-1)" "unprognostic (2.17e-4)" "unprognostic (1.63e-1)" "unprognostic (3.33e-2)" "unprognostic (1.12e-1)" "unprognostic (3.05e-2)" "unprognostic (9.99e-2)" "unprognostic (1.06e-2)" "unprognostic (2.01e-1)" "unprognostic (2.02e-1)" "unprognostic (4.39e-2)" "unprognostic (2.03e-2)" "unprognostic (2.64e-3)" "unprognostic (2.32e-3)" "unprognostic (1.34e-1)" "unprognostic (2.06e-1)" "unprognostic (8.83e-3)" 1.6 1.6 3.5 0.4 3.2 0.1 1.1 4.1 2.4 1.3 0.8 1.0 0.8 1.3 0.7 1.7 1.3 1.4 1.0 2.7 3.8 0.5 1.5 1.3 0.4 3.3 3.1 1.3 0.6 2.1 0.8 3.6 3.4 1.4 0.9 2.5 1.8 1.8 1.1 2.0 1.0 1.1 4.2 0.9 2.0 0.5 3.9 0.4 2.1 0.3 0.5 0.8 1.3 3.8 0.0 0.0 14.6 7.5 6.3 2.7 6.9 2.6 0.1 3.6 5.6 0.3 0.9 0.8 9.6 3.7 0.2 0.4 3.5 2.4 2.8 0.9 0.1 0.0 0.3 0.0 2.5 1.5 0.3 16.1 0.4 2.4 1.0 0.4 1.4 0.3 0.0 0.1 9.0 0.1 0.1 0.4 1.4 0.0 0.1 0.2 1.2 0.0 2.4 0.1 2.0 0.7 0.4 0.1 0.4 3.5 19.7 1.9 3.3 6.7 0.4 11.6 0.1 0.2 1.2 0.1 3.4 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.5 3.2 4.1 2.4 2.7 3.8 3.3 3.1 3.4 4.2 3.9 3.8 5.8 0.0 2.0 0.0 0.9 0.1 2.3 0.6 1.2 27.7 2.2 2.2 3.4 1.5 1.6 1.8 16.7 2.1 1.3 0.7 0.0 1.0 0.0 1.3 7.7 4.8 1.2 0.4 0.0 1.4 1.3 4.8 1.5 2.0 1.3 1.0 4.6 1.7 1.0 23.5 0.0 1.6 0.0 0.0 0.0 0.2 3.4 0.7 1.8 0.0 0.0 5.7 0.0 0.0 0.0 3.1 0.4 2.2 0.5 2.8 0.4 0.5 0.0 6.7 6.6 14.9 3.7 0.4 0.7 1.2 0.4 0.4 0.5 3.0 1.3 1.5 PCDHGA11 PCDH-GAMMA-A11 ENSG00000253873 "Protocadherin gamma subfamily A, 11" Q9Y5H2 5 141421047-141512975 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Bipolar cells: 2.5;Hepatic stellate cells: 1.1;Horizontal cells: 1.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 24.3;ASC TERT1: 25.9;GAMG: 47.4;hTERT-RPE1: 69.8;WM-115: 43.9" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.13e-2)" "unprognostic (1.78e-3)" "unprognostic (9.13e-2)" "unprognostic (1.15e-2)" "unprognostic (1.68e-2)" "unprognostic (2.62e-1)" "unprognostic (2.70e-2)" "unprognostic (1.16e-3)" "unprognostic (1.09e-1)" "unprognostic (1.95e-2)" "unprognostic (2.97e-1)" "unprognostic (2.22e-1)" "unprognostic (3.03e-2)" "unprognostic (3.74e-2)" "unprognostic (3.54e-1)" "unprognostic (4.34e-3)" "unprognostic (1.89e-1)" 0.8 0.7 1.4 0.7 1.8 0.0 0.6 5.1 1.3 0.8 0.7 1.0 0.2 0.7 0.3 0.7 0.9 0.5 1.6 2.1 2.3 0.5 0.4 0.6 0.4 1.8 1.2 1.1 0.5 0.3 0.6 2.2 2.1 0.5 0.3 3.1 0.7 0.7 1.1 1.7 0.4 0.8 2.4 0.3 0.4 0.8 1.9 0.3 0.8 0.5 0.3 0.6 0.8 2.9 0.0 0.0 0.7 2.4 24.3 25.9 0.9 5.5 10.6 4.2 6.6 0.1 0.2 0.6 9.1 5.6 47.4 3.7 0.1 0.6 6.6 0.2 2.4 0.1 0.1 0.0 4.0 0.4 0.0 19.0 0.3 7.4 0.1 69.8 6.5 1.2 0.0 0.1 0.1 0.0 0.0 0.3 2.9 0.0 0.1 17.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 21.3 9.9 0.5 3.2 7.9 0.8 0.1 0.6 0.1 0.0 0.4 0.0 0.1 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 1.8 5.1 1.3 2.1 2.3 1.8 1.2 2.1 2.4 1.9 2.9 0.5 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 2.5 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.7 0.1 0.5 0.8 0.0 0.0 0.0 0.2 0.3 0.5 0.0 0.1 0.0 0.2 1.1 0.0 0.4 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.4 0.0 0.3 0.0 0.1 0.0 0.6 0.0 0.6 0.3 0.1 0.1 0.7 0.0 0.1 0.0 0.2 0.1 0.1 PCDHGA12 "CDH21, FIB3, KIAA0588, PCDH-GAMMA-A12" ENSG00000253159 "Protocadherin gamma subfamily A, 12" O60330 5 141430507-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0" "Cell type enhanced" "Detected in some" "Adipocytes: 2.2;Bipolar cells: 3.8;Cardiomyocytes: 1.6;Endometrial stromal cells: 2.3;Endothelial cells: 2.2;Fibroblasts: 3.2;Skeletal myocytes: 2.0" "Group enriched" "Detected in many" 5 "glioma: 1.7;melanoma: 5.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.2" "Lineage enriched" "Detected in single" 4 "B-cells: 1.2" "Cell line enhanced" "Detected in some" "BJ: 9.3;BJ hTERT+: 15.4;fHDF/TERT166: 23.3;HHSteC: 7.2;HSkMC: 16.5;TIME: 7.5" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 21000 "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.17e-3)" "unprognostic (2.71e-2)" "unprognostic (1.04e-2)" "unprognostic (2.67e-1)" "unprognostic (2.74e-1)" "unprognostic (5.06e-2)" "unprognostic (1.99e-1)" "unprognostic (9.01e-3)" "unprognostic (1.19e-1)" "unprognostic (4.65e-4)" "unprognostic (2.98e-1)" "unprognostic (3.02e-1)" "unprognostic (1.28e-4)" "unprognostic (8.30e-3)" "unprognostic (1.57e-1)" "unprognostic (2.42e-1)" "unprognostic (6.85e-3)" 3.0 4.3 5.3 0.8 6.8 0.0 1.5 5.5 3.7 2.0 0.8 1.3 0.2 2.6 0.4 1.0 1.9 3.9 4.2 5.1 8.4 1.0 0.7 3.1 0.4 10.0 4.2 1.9 1.1 0.3 1.4 2.2 4.5 1.0 0.3 1.4 0.9 1.5 1.3 1.7 0.8 1.7 5.5 1.2 1.0 0.3 5.2 0.9 1.6 1.1 0.4 1.2 2.0 4.6 0.0 0.0 0.1 1.9 0.8 1.4 0.1 9.3 15.4 0.0 0.0 0.0 0.0 0.5 0.0 23.3 0.1 2.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.2 0.0 0.0 16.5 0.0 4.5 0.0 0.0 5.4 0.0 0.0 0.0 3.2 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 2.6 7.5 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.3 6.8 5.5 3.7 5.1 8.4 10.0 4.2 4.5 5.5 5.2 4.6 2.2 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 3.8 0.2 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.3 2.2 0.0 0.0 0.0 0.2 0.0 3.2 1.1 0.1 0.0 0.1 0.7 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.3 0.0 0.0 0.0 0.7 0.0 2.0 1.0 0.0 0.0 0.4 0.0 0.0 0.1 0.7 0.0 0.0 PCDHGA2 PCDH-GAMMA-A2 ENSG00000081853 "Protocadherin gamma subfamily A, 2" Q9Y5H1 5 141338760-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.2;Bipolar cells: 3.2;Cardiomyocytes: 1.8;Fibroblasts: 1.5;Leydig cells: 1.2;Peritubular cells: 2.6;Skeletal myocytes: 1.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 6.4;BJ: 3.9;fHDF/TERT166: 4.4;HSkMC: 3.4;hTERT-RPE1: 3.9" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA038625" Approved Approved "Nucleoplasm,Nucleoli,Vesicles,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Nucleoli, Focal adhesion sites, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA038625: AB_2732480" "unprognostic (2.43e-3)" "unprognostic (2.10e-2)" "unprognostic (1.32e-2)" "unprognostic (4.54e-1)" "unprognostic (2.92e-1)" "unprognostic (1.14e-1)" "unprognostic (3.01e-1)" "unprognostic (2.82e-1)" "unprognostic (1.56e-1)" "unprognostic (1.18e-1)" "unprognostic (9.01e-2)" "unprognostic (4.32e-2)" "unprognostic (8.45e-3)" "unprognostic (9.68e-3)" "unprognostic (1.04e-2)" "unprognostic (1.18e-2)" "unprognostic (2.23e-4)" 2.2 1.6 1.8 0.7 1.4 0.0 1.9 2.7 2.5 3.0 0.7 1.5 0.1 2.9 1.9 0.8 3.1 1.4 4.9 2.9 1.5 1.1 0.7 2.0 0.2 3.8 3.2 6.3 1.8 3.8 2.6 0.7 2.6 1.9 0.3 2.3 1.2 2.2 1.0 1.0 0.6 2.1 3.5 0.6 0.9 2.3 2.6 0.8 1.6 1.1 0.2 1.4 1.7 2.2 0.0 0.7 0.3 0.2 2.8 6.4 0.0 3.9 1.3 0.3 0.5 0.0 0.0 0.1 0.4 4.4 0.5 0.1 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 3.4 0.1 0.0 0.2 3.9 1.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.1 0.5 0.0 0.2 0.5 0.0 2.3 0.1 0.3 0.4 0.0 2.3 0.6 0.3 0.2 0.0 0.0 0.3 0.0 1.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.4 2.7 2.5 2.9 1.5 3.8 3.2 2.6 3.5 2.6 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 3.2 0.3 0.9 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 1.1 0.9 0.0 0.0 0.0 0.2 0.0 1.5 0.0 0.1 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 2.6 0.0 0.0 0.0 0.4 0.0 0.4 0.0 1.5 0.5 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 PCDHGA3 PCDH-GAMMA-A3 ENSG00000254245 "Protocadherin gamma subfamily A, 3" Q9Y5H0 5 141343829-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.4;Cardiomyocytes: 1.6;Endometrial stromal cells: 1.9;Fibroblasts: 1.3;Horizontal cells: 3.3;Skeletal myocytes: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 7.1;BJ: 2.3;EFO-21: 5.7" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (6.47e-2)" "unprognostic (4.79e-2)" "unprognostic (1.48e-2)" "unprognostic (1.64e-1)" "unprognostic (4.53e-2)" "unprognostic (1.03e-1)" "unprognostic (2.35e-1)" "unprognostic (1.85e-1)" "unprognostic (7.44e-2)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (3.17e-2)" "unprognostic (2.43e-1)" "unprognostic (2.32e-3)" "unprognostic (7.12e-3)" "unprognostic (3.31e-2)" "unprognostic (2.52e-4)" 1.2 1.2 2.6 0.2 1.7 0.0 0.9 2.2 2.6 1.6 0.1 0.7 0.0 1.4 0.9 0.2 1.2 0.9 3.7 2.5 1.8 0.5 0.6 0.9 0.0 3.8 2.9 2.5 0.9 0.6 1.2 1.7 2.2 0.7 0.2 1.8 0.7 0.8 0.8 0.5 0.2 0.9 3.4 0.2 0.4 1.5 2.9 0.2 0.8 0.9 0.1 0.8 0.9 2.5 0.0 0.0 7.1 0.0 0.0 0.9 0.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 5.7 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.7 2.2 2.6 2.5 1.8 3.8 2.9 2.2 3.4 2.9 2.5 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.1 0.5 1.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 1.9 0.9 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 1.6 0.9 0.1 0.5 0.0 0.0 0.1 0.0 0.4 0.0 0.0 PCDHGA4 PCDH-GAMMA-A4 ENSG00000262576 "Protocadherin gamma subfamily A, 4" Q9Y5G9 5 141355021-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.0;Skeletal myocytes: 1.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 7.4;BJ: 4.3;HSkMC: 4.3;HUVEC TERT2: 4.3;U-87 MG: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.27e-2)" "unprognostic (4.55e-3)" "unprognostic (2.00e-2)" "unprognostic (6.54e-4)" "unprognostic (1.87e-2)" "unprognostic (1.06e-2)" "unprognostic (1.02e-1)" "unprognostic (1.20e-2)" "unprognostic (5.62e-2)" "unprognostic (3.76e-1)" "unprognostic (6.31e-2)" "unprognostic (1.74e-1)" "unprognostic (2.94e-2)" "unprognostic (1.30e-2)" "unprognostic (2.30e-2)" "unprognostic (1.65e-1)" "unprognostic (2.31e-4)" 1.7 1.3 1.6 0.4 1.8 0.0 0.9 3.7 1.7 1.3 0.0 0.9 0.2 1.6 0.8 0.4 0.9 0.8 1.5 2.9 1.5 0.4 0.3 1.0 0.1 2.1 2.4 1.6 2.1 2.3 1.0 0.8 1.7 1.1 0.3 1.5 0.8 1.1 0.7 0.5 0.3 1.5 2.0 0.3 0.4 0.7 2.1 0.2 0.7 1.0 0.1 0.7 0.8 2.5 0.0 0.1 0.8 0.4 3.3 7.4 0.0 4.3 3.4 0.2 0.8 0.0 0.1 0.7 1.4 3.7 1.3 0.0 0.1 0.1 0.4 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.3 4.3 0.1 0.0 0.0 2.6 4.3 0.0 0.1 0.2 1.8 0.6 0.2 0.2 0.1 0.0 0.2 0.3 1.2 0.1 0.2 0.0 0.6 1.3 0.2 0.2 0.9 0.3 1.6 0.0 2.8 1.8 0.5 2.4 0.3 0.1 0.2 0.1 6.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.8 3.7 1.7 2.9 1.5 2.1 2.4 1.7 2.0 2.1 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 PCDHGA5 "CDH-GAMMA-A5, ME3, PCDH-GAMMA-A5" ENSG00000253485 "Protocadherin gamma subfamily A, 5" Q9Y5G8 5 141364232-141512979 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 4.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.5;Endometrial stromal cells: 9.2;Horizontal cells: 10.1;Sertoli cells: 6.6;Skeletal myocytes: 5.7" "Cancer enhanced" "Detected in single" "prostate cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 15.8;ASC TERT1: 6.2" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.61e-2)" "unprognostic (1.04e-2)" "unprognostic (5.28e-2)" "unprognostic (4.83e-1)" "unprognostic (6.60e-3)" "unprognostic (5.71e-2)" "unprognostic (8.46e-2)" "unprognostic (6.53e-3)" "unprognostic (4.07e-1)" "unprognostic (9.40e-2)" "unprognostic (1.38e-1)" "unprognostic (1.05e-1)" "unprognostic (1.12e-1)" "unprognostic (5.90e-2)" "unprognostic (3.93e-2)" "unprognostic (1.55e-2)" "unprognostic (8.38e-4)" 1.0 0.6 1.0 0.3 1.6 0.1 1.2 4.9 1.1 2.5 0.0 1.1 0.1 2.0 0.6 0.8 1.4 1.1 1.9 1.2 1.2 0.3 0.2 1.1 0.2 2.2 2.1 2.0 0.6 0.6 0.9 0.6 1.0 1.4 0.3 1.2 0.8 0.9 0.6 0.7 0.4 1.0 1.2 0.2 0.5 0.3 1.2 0.3 0.5 0.7 0.1 1.0 1.3 2.0 0.0 0.4 0.2 0.1 15.8 6.2 0.0 0.7 0.1 0.1 0.3 0.0 0.0 0.8 0.3 0.3 0.8 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.2 0.1 0.1 0.1 0.0 1.5 0.2 0.0 0.0 0.4 0.5 0.0 0.1 0.5 0.6 0.3 0.5 0.6 0.1 0.0 0.3 0.8 0.6 0.1 0.0 0.0 0.2 0.2 0.0 0.2 0.3 0.2 1.4 0.0 0.9 0.5 0.1 0.9 0.6 0.1 0.9 0.1 0.3 0.1 0.7 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 1.0 1.6 4.9 1.1 1.2 1.2 2.2 2.1 1.0 1.2 1.2 2.0 1.8 0.0 1.1 0.0 0.2 0.1 0.8 0.1 0.6 11.5 0.3 0.4 2.6 0.0 0.7 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.1 0.4 9.2 1.9 0.0 0.0 0.0 0.2 0.0 4.0 0.0 0.2 1.3 0.6 1.4 0.3 0.1 10.1 0.0 0.0 0.0 0.3 0.0 0.0 3.7 0.4 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.5 0.0 0.1 0.1 1.3 6.6 5.7 1.7 0.0 0.3 0.3 0.0 0.0 0.6 0.9 0.0 0.4 PCDHGA6 PCDH-GAMMA-A6 ENSG00000253731 "Protocadherin gamma subfamily A, 6" Q9Y5G7 5 141373891-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 10.6;Cardiomyocytes: 5.0;Endometrial stromal cells: 4.6;Hepatic stellate cells: 3.6;Skeletal myocytes: 5.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 9.6;T-47d: 5.6;WM-115: 12.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (4.49e-2)" "unprognostic (8.91e-3)" "unprognostic (5.45e-2)" "unprognostic (1.43e-1)" "unprognostic (1.15e-1)" "unprognostic (1.49e-2)" "unprognostic (1.16e-1)" "unprognostic (1.18e-1)" "unprognostic (1.25e-1)" "unprognostic (2.07e-2)" "unprognostic (3.86e-3)" "unprognostic (2.02e-2)" "unprognostic (5.26e-2)" "unprognostic (7.44e-2)" "unprognostic (5.21e-2)" "unprognostic (1.11e-1)" "unprognostic (4.19e-3)" 1.4 1.1 1.6 0.7 1.8 0.1 1.3 7.2 1.6 2.7 0.0 2.0 0.2 3.2 1.4 0.8 2.0 1.1 2.7 1.7 1.8 0.8 0.5 1.5 0.4 1.8 1.7 3.5 1.2 1.1 1.8 2.3 0.9 1.2 0.4 2.0 1.5 1.6 0.9 1.5 0.8 2.0 0.8 0.9 0.7 0.8 2.0 0.5 1.2 1.0 0.4 1.6 1.5 1.9 0.0 0.3 2.7 0.4 1.3 4.7 0.1 2.1 0.7 1.1 1.1 0.0 0.1 2.0 2.6 3.3 1.0 0.4 0.1 0.4 0.7 0.0 0.2 0.0 0.3 0.2 0.7 0.1 0.1 4.9 0.3 0.2 0.1 1.0 1.6 0.1 0.2 1.1 0.3 0.4 0.7 1.7 0.3 0.0 0.1 1.4 0.4 0.0 0.3 0.1 9.6 0.7 0.1 0.3 0.6 0.6 5.6 0.1 4.8 0.7 0.3 0.7 0.7 0.4 1.7 0.4 0.8 0.7 12.2 0.4 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.0 1.6 1.8 7.2 1.6 1.7 1.8 1.8 1.7 0.9 0.8 2.0 1.9 2.8 0.0 2.2 0.0 0.4 0.0 0.8 0.0 0.0 10.6 0.3 1.0 5.0 1.5 0.6 0.0 0.0 0.1 0.3 0.0 0.0 0.4 0.5 0.4 4.6 1.8 0.0 0.4 0.0 1.5 0.1 2.2 0.0 0.4 0.0 0.6 3.6 0.7 0.1 1.7 0.0 0.2 0.0 0.3 0.0 0.3 1.2 0.5 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.6 0.1 2.2 1.6 0.4 0.0 0.3 0.7 0.9 0.0 5.2 1.9 0.3 0.3 0.5 0.0 0.3 0.2 0.5 0.2 0.2 PCDHGA7 PCDH-GAMMA-A7 ENSG00000253537 "Protocadherin gamma subfamily A, 7" Q9Y5G6 5 141382739-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.3;Cardiomyocytes: 1.6;Endometrial stromal cells: 2.2;Skeletal myocytes: 2.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 11.3;BJ hTERT+: 20.8;hTERT-RPE1: 10.9;SH-SY5Y: 18.6;T-47d: 8.1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.00e-2)" "unprognostic (4.73e-3)" "unprognostic (1.42e-1)" "unprognostic (7.49e-2)" "unprognostic (2.10e-1)" "unprognostic (6.85e-2)" "unprognostic (2.61e-1)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (5.78e-2)" "unprognostic (3.72e-2)" "unprognostic (1.66e-1)" "unprognostic (3.56e-1)" "unprognostic (4.21e-3)" "unprognostic (6.30e-2)" "unprognostic (4.99e-2)" "unprognostic (1.42e-3)" 0.5 0.4 1.0 0.2 0.9 0.0 0.6 5.9 1.0 1.2 0.0 1.1 0.1 1.3 1.1 0.5 1.0 0.4 1.5 1.1 0.6 0.6 0.4 0.7 0.1 1.5 1.2 1.5 0.7 2.2 0.8 1.3 0.9 0.9 0.3 1.6 0.8 0.8 0.7 1.0 0.4 0.8 1.0 0.4 0.3 0.5 1.3 0.2 1.9 0.5 0.1 0.9 0.7 1.5 0.0 1.6 2.3 0.0 6.6 11.3 0.0 3.3 20.8 4.2 6.1 0.0 0.0 0.5 5.2 0.7 0.2 0.2 0.0 0.1 3.4 0.0 0.3 0.0 0.4 0.2 1.1 0.0 0.0 5.0 0.1 0.0 0.7 10.9 1.7 0.0 0.0 0.1 0.1 0.1 0.6 0.3 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.4 18.6 0.0 0.1 0.1 3.7 8.1 0.0 6.7 0.1 0.1 3.1 0.1 0.1 1.9 0.0 0.5 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 5.9 1.0 1.1 0.6 1.5 1.2 0.9 1.0 1.3 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 4.3 0.3 0.3 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 2.2 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.6 0.0 2.8 0.9 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.3 PCDHGA8 "KIAA0327, PCDH-GAMMA-A8" ENSG00000253767 "Protocadherin gamma subfamily A, 8" Q9Y5G5 5 141390157-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 7 "brain: 3.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.4;Cardiomyocytes: 3.5;Horizontal cells: 3.3;Skeletal myocytes: 5.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.28e-2)" "unprognostic (2.27e-2)" "unprognostic (4.86e-2)" "unprognostic (3.38e-2)" "unprognostic (2.80e-1)" "unprognostic (4.10e-2)" "unprognostic (7.68e-2)" "unprognostic (2.30e-2)" "unprognostic (1.83e-2)" "unprognostic (2.23e-1)" "unprognostic (1.24e-1)" "unprognostic (1.35e-2)" "unprognostic (1.49e-3)" "unprognostic (7.59e-2)" "unprognostic (3.92e-2)" "unprognostic (3.38e-1)" "unprognostic (1.99e-3)" 0.1 0.1 0.6 0.1 0.6 0.4 0.1 3.9 0.8 0.2 0.2 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.5 0.8 0.5 0.0 0.1 0.1 0.1 1.1 0.7 0.3 0.1 0.0 0.2 0.2 0.7 0.1 0.1 0.5 0.1 0.0 0.3 0.3 0.1 0.1 0.3 0.1 0.1 0.1 0.9 0.1 0.4 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.3 0.1 0.2 0.6 0.1 0.6 0.4 0.4 0.1 0.0 0.1 0.3 0.2 0.4 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.6 0.2 0.4 0.6 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.6 0.6 3.9 0.8 0.8 0.5 1.1 0.7 0.7 0.3 0.9 1.2 1.2 0.0 0.6 0.0 0.1 0.0 0.9 0.0 0.0 11.4 0.3 0.3 3.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.6 0.1 2.1 1.2 0.0 0.0 0.0 0.6 0.0 1.1 0.0 0.2 0.0 0.3 0.4 0.7 0.1 3.3 0.0 0.0 0.0 0.3 0.0 0.0 2.1 0.2 0.0 0.0 0.0 1.3 1.0 0.0 0.0 0.1 0.1 1.5 0.0 0.7 0.0 0.2 0.0 1.7 0.0 5.2 0.9 0.7 1.1 0.0 0.0 0.0 0.1 0.5 0.0 0.5 PCDHGA9 PCDH-GAMMA-A9 ENSG00000261934 "Protocadherin gamma subfamily A, 9" Q9Y5G4 5 141402932-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.5;Cardiomyocytes: 1.3;Endometrial stromal cells: 1.5;Horizontal cells: 3.3;Skeletal myocytes: 2.3" "Cancer enhanced" "Detected in some" "glioma: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.6;HSkMC: 4.0;hTERT-RPE1: 16.9;TIME: 4.6;U-87 MG: 5.1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.98e-2)" "unprognostic (7.47e-3)" "unprognostic (9.86e-3)" "unprognostic (2.22e-1)" "unprognostic (4.68e-2)" "unprognostic (4.96e-2)" "unprognostic (1.61e-1)" "unprognostic (2.15e-1)" "unprognostic (2.39e-1)" "unprognostic (1.87e-3)" "unprognostic (2.26e-1)" "unprognostic (1.79e-1)" "unprognostic (4.48e-3)" "unprognostic (1.94e-2)" "unprognostic (8.83e-2)" "unprognostic (2.71e-1)" "unprognostic (1.83e-2)" 1.8 1.6 3.3 0.7 3.5 0.1 1.3 6.6 3.2 2.0 0.4 1.2 0.5 2.5 1.1 1.4 1.9 2.0 1.1 3.7 2.6 0.8 0.4 1.5 0.5 3.6 3.4 2.8 0.8 1.1 0.9 1.0 3.8 1.5 0.7 4.4 1.1 2.2 0.8 1.7 0.6 1.8 3.7 1.1 0.8 0.4 3.6 0.5 1.4 1.2 0.7 1.2 1.4 5.7 0.0 0.1 0.6 1.6 0.1 0.2 0.2 0.7 0.0 0.6 0.6 0.2 0.4 1.3 3.6 2.0 0.3 0.1 0.1 0.2 0.7 0.0 0.3 0.0 0.1 0.0 1.1 0.0 0.2 4.0 0.1 0.4 0.3 16.9 1.0 0.0 0.1 0.2 0.3 0.3 0.1 0.5 0.2 0.0 0.0 0.1 0.4 0.0 0.1 0.2 0.4 1.1 0.4 0.1 0.5 0.4 0.9 0.4 4.6 0.3 0.3 0.1 2.5 0.2 0.0 0.0 5.1 0.1 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 3.5 6.6 3.2 3.7 2.6 3.6 3.4 3.8 3.7 3.6 5.7 0.6 0.0 0.0 0.0 0.1 0.3 0.2 0.3 0.6 4.5 0.2 0.3 1.3 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 1.5 0.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.1 0.4 0.2 0.1 3.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 2.3 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.1 PCDHGB1 PCDH-GAMMA-B1 ENSG00000254221 "Protocadherin gamma subfamily B, 1" Q9Y5G3 5 141350102-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.5" "Cell type enhanced" "Detected in some" "Early spermatids: 5.7;Late spermatids: 7.6;Melanocytes: 1.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 12.9;ASC TERT1: 6.6;hTERT-RPE1: 7.1;T-47d: 8.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA076182" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Focal adhesion sites,Midbody" Yes No "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 34: Spermatids - Unknown function" "Vesicles, Plasma membrane" "Nucleoplasm, Focal adhesion sites, Midbody" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA076182: AB_2686783" "unprognostic (1.53e-2)" "unprognostic (1.94e-3)" "unprognostic (3.21e-1)" "unprognostic (4.38e-3)" "unprognostic (2.98e-1)" "unprognostic (8.36e-3)" "unprognostic (2.37e-1)" "unprognostic (9.57e-2)" "unprognostic (8.57e-2)" "unprognostic (1.06e-1)" "unprognostic (3.44e-2)" "unprognostic (4.78e-2)" "unprognostic (6.33e-2)" "unprognostic (3.15e-2)" "unprognostic (8.75e-2)" "unprognostic (1.93e-1)" "unprognostic (7.63e-3)" 0.6 0.7 1.8 0.1 1.2 0.0 0.5 2.1 1.6 0.6 0.0 0.3 0.0 1.2 0.4 0.3 0.4 0.5 0.5 2.9 1.6 0.4 0.1 0.6 0.0 1.9 3.3 1.4 0.8 2.3 1.0 0.2 2.4 0.6 0.1 1.6 0.3 0.9 0.2 0.2 0.1 0.9 2.4 0.1 0.1 0.4 1.8 0.0 0.6 0.3 0.0 0.3 0.3 3.5 0.1 1.9 1.6 0.0 12.9 6.6 0.1 1.2 3.2 0.5 0.7 0.2 0.5 0.5 4.2 0.5 3.1 0.6 0.3 0.2 0.4 0.0 0.8 0.0 0.2 1.2 0.2 0.0 0.0 1.0 0.0 0.0 0.0 7.1 0.1 0.0 0.2 0.2 3.0 1.7 0.4 0.3 0.2 0.0 0.0 0.0 2.4 0.1 0.0 0.0 1.0 0.7 0.0 0.8 0.1 1.2 8.6 0.0 1.0 0.2 1.3 1.1 0.0 0.0 2.4 0.3 2.5 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.2 2.1 1.6 2.9 1.6 1.9 3.3 2.4 2.4 1.8 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.7 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 1.8 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PCDHGB2 PCDH-GAMMA-B2 ENSG00000253910 "Protocadherin gamma subfamily B, 2" Q9Y5G2 5 141360042-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.2;Cardiomyocytes: 1.4;Endometrial stromal cells: 1.0;Fibroblasts: 1.2" "Cancer enriched" "Detected in many" 5 "glioma: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 13.5;ASC TERT1: 9.8;LHCN-M2: 8.2;REH: 7.8" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077526" Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane, Cytosol" Nucleoplasm "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077526: AB_2732350" "unprognostic (7.14e-3)" "unprognostic (8.79e-3)" "unprognostic (3.21e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.67e-4)" "unprognostic (1.10e-2)" "unprognostic (2.19e-4)" "unprognostic (2.68e-1)" "unprognostic (2.64e-1)" "unprognostic (1.78e-1)" "unprognostic (1.05e-1)" "unprognostic (8.46e-3)" "unprognostic (4.59e-2)" "unprognostic (2.57e-1)" "unprognostic (3.06e-2)" "unprognostic (1.29e-1)" "unprognostic (3.36e-4)" 1.5 1.0 2.6 0.6 3.6 0.1 1.1 6.3 2.8 2.1 0.0 1.1 0.2 3.0 0.9 0.9 1.6 1.9 1.8 3.1 3.2 0.7 0.7 1.7 0.3 3.7 3.3 2.8 0.8 1.2 0.9 1.1 3.6 1.3 0.8 1.6 0.8 1.2 0.8 0.8 0.5 1.5 3.0 0.6 0.6 0.5 2.2 0.4 0.7 0.9 0.3 0.9 1.1 5.5 0.1 0.3 2.0 0.2 13.5 9.8 0.1 2.1 2.9 0.6 3.2 0.0 0.3 3.7 1.0 1.7 7.1 0.5 0.4 0.3 1.0 0.0 0.2 0.0 0.3 0.4 0.5 0.2 0.2 2.5 0.5 0.2 0.1 4.7 1.7 0.1 0.2 1.2 8.2 0.5 2.9 0.7 0.1 0.9 0.9 7.8 2.6 0.2 0.2 0.3 1.5 1.6 0.2 0.4 0.4 1.5 3.0 0.2 5.9 2.9 0.6 4.4 3.9 0.2 2.2 0.6 3.1 1.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.6 6.3 2.8 3.1 3.2 3.7 3.3 3.6 3.0 2.2 5.5 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.6 2.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 1.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 PCDHGB3 PCDH-GAMMA-B3 ENSG00000262209 "Protocadherin gamma subfamily B, 3" Q9Y5G1 5 141370242-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.8" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 1.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 10.4;ASC TERT1: 8.4;fHDF/TERT166: 3.5;TIME: 5.5" "HPA008755, HPA010580, HPA035822, HPA035823" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA035822: , HPA035823: AB_2674802" "unprognostic (6.93e-3)" "unprognostic (9.10e-4)" "unprognostic (1.35e-1)" "unprognostic (7.05e-2)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (7.83e-2)" "unprognostic (1.92e-1)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (3.51e-2)" "unprognostic (5.81e-2)" "unprognostic (3.11e-1)" "unprognostic (3.62e-2)" "unprognostic (3.89e-2)" "unprognostic (2.80e-3)" 0.7 0.3 0.4 0.2 0.8 0.0 0.5 3.8 0.8 0.8 0.0 0.8 0.0 1.0 0.6 0.3 0.7 0.4 1.2 0.9 0.5 0.3 0.2 0.5 0.2 1.3 1.4 1.2 0.7 1.1 0.7 0.4 0.6 0.4 0.3 0.8 0.8 0.4 0.5 0.6 0.3 0.7 0.6 0.4 0.4 0.4 0.8 0.3 0.6 0.5 0.2 0.6 0.6 1.4 0.0 0.6 0.4 0.3 10.4 8.4 0.2 1.2 2.0 0.7 0.8 0.0 0.0 1.8 0.3 3.5 0.6 0.5 0.0 0.2 0.5 0.0 0.2 0.0 0.2 0.1 0.4 0.1 0.0 2.1 0.4 0.2 0.1 0.2 1.0 0.0 0.2 0.8 0.2 0.4 0.6 0.9 0.1 0.0 0.1 1.5 0.6 0.0 0.2 0.1 2.4 0.5 0.0 0.0 0.2 0.3 0.6 0.0 5.5 0.5 0.1 0.5 0.6 0.2 1.8 0.2 0.4 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 3.8 0.8 0.9 0.5 1.3 1.4 0.6 0.6 0.8 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDHGB4 "CDH20, FIB2, PCDH-GAMMA-B4" ENSG00000253953 "Protocadherin gamma subfamily B, 4" Q9UN71 5 141387698-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.1;Horizontal cells: 1.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 43.3;SuSa: 15.5;TIME: 22.7" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.33e-1)" "unprognostic (1.83e-3)" "unprognostic (2.91e-1)" "unprognostic (1.18e-1)" "unprognostic (1.23e-2)" "unprognostic (9.25e-3)" "unprognostic (2.20e-1)" "unprognostic (1.25e-2)" "unprognostic (1.99e-1)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "unprognostic (3.78e-2)" "unprognostic (2.31e-2)" "unprognostic (2.70e-2)" "unprognostic (2.62e-1)" "unprognostic (1.13e-1)" "unprognostic (3.27e-2)" 1.3 1.1 1.3 0.4 1.5 0.0 0.9 4.4 1.4 1.5 1.8 1.1 0.2 1.6 1.5 0.7 1.3 0.5 1.5 2.0 3.2 1.4 1.6 1.1 0.1 2.0 2.0 2.4 1.0 1.9 1.2 3.0 1.5 1.2 0.4 1.4 1.6 1.4 1.0 1.7 0.5 1.0 1.4 0.4 0.4 0.5 2.5 0.7 1.7 0.8 0.2 1.0 1.1 1.5 0.0 1.1 11.1 0.1 6.9 8.5 1.3 10.8 43.3 4.4 3.0 0.0 0.0 0.4 8.3 0.3 0.2 3.3 0.0 0.0 4.6 0.0 0.0 0.0 0.2 2.4 2.8 0.0 0.0 8.4 0.1 4.1 0.0 0.1 6.7 0.0 0.4 0.1 0.0 0.0 1.1 0.2 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.4 0.0 15.5 5.6 4.2 22.7 6.0 1.8 0.3 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 1.5 4.4 1.4 2.0 3.2 2.0 2.0 1.5 1.4 2.5 1.5 0.2 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.6 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 PCDHGB5 PCDH-GAMMA-B5 ENSG00000276547 "Protocadherin gamma subfamily B, 5" Q9Y5G0 5 141397987-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 20.3" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.2;Bipolar cells: 1.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 66.3;ASC TERT1: 49.6;BJ hTERT+ SV40 Large T+: 29.2;BJ hTERT+ SV40 Large T+ RasG12V: 32.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (2.71e-3)" "unprognostic (1.95e-2)" "unprognostic (1.09e-1)" "unprognostic (4.14e-2)" "unprognostic (2.35e-1)" "unprognostic (1.20e-1)" "unprognostic (3.64e-2)" "unprognostic (2.34e-2)" "unprognostic (1.54e-1)" "unprognostic (1.23e-1)" "unprognostic (1.90e-1)" "unprognostic (2.29e-1)" "unprognostic (1.69e-4)" "unprognostic (9.63e-3)" "unprognostic (3.21e-1)" "unprognostic (1.12e-1)" "unprognostic (8.25e-4)" 2.8 2.7 3.6 1.1 3.6 0.0 1.8 5.8 3.1 2.0 3.3 1.7 0.7 3.1 2.0 1.9 2.8 1.6 2.9 3.9 6.4 2.2 2.1 2.7 0.4 5.1 4.7 5.7 3.8 20.3 1.7 4.8 5.4 3.0 0.9 3.1 4.7 3.9 2.1 3.8 0.8 2.8 5.3 1.3 1.5 1.9 4.9 1.3 4.5 1.9 0.8 1.9 2.1 6.1 0.0 2.4 0.3 0.0 66.3 49.6 1.3 18.3 0.0 29.2 32.5 2.9 10.0 10.6 23.4 20.5 0.0 13.9 0.0 7.6 16.4 0.0 3.1 0.0 0.0 0.1 6.9 0.0 6.5 17.6 1.5 1.7 9.4 12.6 9.0 0.0 0.2 0.0 1.0 8.1 0.0 1.5 0.4 0.0 0.0 0.0 0.0 0.0 1.6 5.5 0.0 0.1 0.0 0.1 0.0 2.0 19.1 0.1 9.2 0.0 2.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 3.6 5.8 3.1 3.9 6.4 5.1 4.7 5.4 5.3 4.9 6.1 0.5 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.2 1.5 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.6 0.6 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.8 0.5 0.0 0.0 0.9 0.0 0.1 0.0 0.1 0.0 0.1 PCDHGB6 PCDH-GAMMA-B6 ENSG00000253305 "Protocadherin gamma subfamily B, 6" Q9Y5F9 5 141408021-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.9;Cone photoreceptor cells: 6.2;Horizontal cells: 10.1;Skeletal myocytes: 5.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 16.0;EFO-21: 5.4;HSkMC: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.11e-1)" "unprognostic (4.18e-2)" "unprognostic (2.63e-1)" "unprognostic (7.81e-2)" "unprognostic (1.04e-1)" "unprognostic (1.90e-1)" "unprognostic (1.18e-1)" "unprognostic (1.85e-2)" "unprognostic (3.51e-1)" "unprognostic (1.11e-1)" "unprognostic (4.77e-2)" "unprognostic (9.89e-2)" "unprognostic (1.43e-1)" "unprognostic (2.17e-2)" "unprognostic (3.27e-1)" "unprognostic (1.21e-2)" "unprognostic (7.71e-4)" 3.1 3.1 3.0 0.9 3.6 0.4 2.2 5.0 2.4 2.9 2.9 2.4 0.5 3.2 2.0 1.2 2.9 1.7 2.4 2.5 3.5 1.1 1.3 2.0 0.7 3.6 3.5 6.0 1.2 2.8 1.8 3.1 3.2 1.4 0.7 2.8 2.2 2.4 2.9 2.1 1.0 1.9 3.3 1.5 1.1 0.6 3.7 0.6 2.6 1.5 0.6 1.8 2.3 3.9 0.0 0.1 16.0 0.1 0.5 0.6 0.8 1.4 0.0 0.4 0.9 0.2 0.2 1.4 5.4 0.9 0.2 0.3 0.0 0.3 1.0 0.0 0.3 0.0 0.2 0.1 1.3 0.1 0.1 3.6 1.8 0.8 0.1 0.1 0.5 0.3 0.1 0.2 0.1 0.3 0.1 1.1 0.6 0.0 0.0 0.2 0.0 0.1 2.5 0.2 0.2 0.3 0.0 0.1 0.1 0.4 1.2 0.3 2.6 0.1 0.2 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.7 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 3.0 3.6 5.0 2.4 2.5 3.5 3.6 3.5 3.2 3.3 3.7 3.9 3.6 3.2 0.5 0.0 1.0 0.0 1.5 0.0 0.0 6.9 0.6 0.4 3.9 0.0 1.3 0.0 6.2 0.2 0.6 0.4 0.0 0.7 0.0 0.6 3.8 2.6 0.0 0.0 0.0 1.2 0.1 3.3 1.1 0.5 0.0 0.4 1.4 0.7 0.3 10.1 0.0 0.4 0.0 0.0 0.0 0.2 1.8 0.2 0.0 0.0 0.1 2.7 0.0 0.0 0.0 2.0 0.1 1.2 1.5 0.8 0.1 0.3 0.7 2.5 0.0 5.2 3.2 0.2 0.5 0.3 0.1 0.1 0.7 0.8 0.4 0.8 PCDHGB7 "ME6, PCDH-GAMMA-B7" ENSG00000254122 "Protocadherin gamma subfamily B, 7" Q9Y5F8 5 141417645-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Bipolar cells: 7.9;Fibroblasts: 3.4;Horizontal cells: 3.3;Skeletal myocytes: 5.9" "Cancer enhanced" "Detected in many" "glioma: 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "AN3-CA: 86.7;HSkMC: 26.7;hTERT-RPE1: 72.4" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.22e-2)" "unprognostic (2.55e-2)" "unprognostic (7.39e-3)" "unprognostic (2.95e-1)" "unprognostic (1.49e-1)" "unprognostic (3.34e-1)" "unprognostic (1.98e-1)" "unprognostic (1.25e-1)" "unprognostic (8.40e-2)" "unprognostic (4.43e-2)" "unprognostic (2.61e-2)" "unprognostic (1.88e-2)" "unprognostic (3.05e-1)" "unprognostic (2.22e-2)" "unprognostic (1.44e-1)" "unprognostic (1.91e-1)" "unprognostic (5.68e-2)" 5.2 4.6 4.6 1.8 4.7 0.1 4.2 10.8 3.5 4.9 5.0 5.0 0.9 5.7 2.2 3.0 4.4 4.4 4.3 4.5 7.0 2.4 1.5 5.8 1.2 6.0 6.0 8.1 1.7 4.3 2.2 5.5 5.3 3.8 1.7 5.8 3.7 5.5 3.0 3.3 2.1 5.1 7.7 2.7 2.4 1.9 5.0 1.5 4.0 4.1 0.9 3.3 3.8 7.3 0.0 0.0 2.9 86.7 1.9 0.3 0.9 5.7 0.7 2.1 4.3 0.1 5.3 0.7 4.6 11.7 0.8 1.4 0.2 1.0 2.0 0.1 0.6 0.0 0.2 0.0 6.4 0.5 0.1 26.7 0.7 1.7 0.9 72.4 4.6 0.2 0.0 0.0 0.3 0.0 0.0 0.1 1.0 0.0 0.6 10.1 1.9 0.0 0.2 0.0 9.3 12.8 0.2 0.0 0.0 1.0 1.0 0.9 11.5 10.3 0.2 0.9 0.1 0.1 0.2 0.0 1.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.6 4.7 10.8 3.5 4.5 7.0 6.0 6.0 5.3 7.7 5.0 7.3 2.2 3.2 1.3 0.0 0.3 0.4 0.8 0.0 0.0 7.9 0.3 0.5 1.4 0.0 0.1 0.0 2.1 0.1 0.0 0.0 0.0 0.2 0.1 0.4 2.1 2.2 0.0 0.0 0.0 0.5 0.1 3.4 0.0 0.3 1.3 0.5 0.4 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.4 0.0 1.2 0.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.1 0.0 1.9 0.1 0.4 0.0 0.3 0.0 0.7 0.0 5.9 2.2 0.0 0.1 0.5 0.4 0.0 0.0 1.2 0.1 0.2 PCDHGC4 PCDH-GAMMA-C4 ENSG00000242419 "Protocadherin gamma subfamily C, 4" Q9Y5F7 5 141484997-141512979 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 31.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.1;Horizontal cells: 3.3" "Cancer enriched" "Detected in single" 10 "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 9.1;SCLC-21H: 7.3;SH-SY5Y: 14.2;SuSa: 10.0" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (6.05e-2)" "unprognostic (1.26e-3)" "unprognostic (4.78e-2)" "unprognostic (1.41e-1)" "unprognostic (3.44e-1)" "unprognostic (7.84e-2)" "unprognostic (9.48e-2)" "unprognostic (3.27e-1)" "unprognostic (4.55e-1)" "unprognostic (1.17e-1)" "unprognostic (8.72e-3)" "unprognostic (4.73e-3)" "unprognostic (2.20e-4)" "unprognostic (8.78e-2)" "unprognostic (3.06e-2)" "unprognostic (1.47e-1)" "unprognostic (2.75e-2)" 0.2 1.1 17.3 0.1 12.2 0.0 0.2 19.3 14.6 0.3 0.1 0.6 0.0 0.4 0.2 0.2 0.3 0.2 2.2 12.7 13.9 0.1 0.1 0.4 0.1 12.9 21.9 0.3 0.3 0.0 1.1 0.1 10.3 0.2 0.1 6.6 0.3 0.1 0.7 0.5 0.1 0.2 22.4 0.1 0.2 0.9 14.3 0.0 0.1 0.3 0.2 0.2 0.3 31.4 0.0 0.0 0.9 0.2 0.2 0.7 0.4 0.1 0.1 0.1 0.2 0.0 0.0 0.2 0.8 0.9 0.1 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.0 1.3 0.0 0.0 9.1 0.5 0.0 0.0 0.1 7.3 14.2 0.1 0.0 0.1 10.0 0.1 0.3 0.1 0.8 0.1 0.2 0.6 0.2 0.0 0.2 0.6 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 12.2 19.3 14.6 12.7 13.9 12.9 21.9 10.3 22.4 14.3 31.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PCDHGC5 PCDH-GAMMA-C5 ENSG00000240764 "Protocadherin gamma subfamily C, 5" Q9Y5F6 5 141489081-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 28.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "glioma: 3.1;head and neck cancer: 0.8" "Region enhanced" "Detected in many" "hippocampal formation: 28.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 4.6;SuSa: 7.4;U-138 MG: 14.4;U-251 MG: 6.5;U-87 MG: 8.9" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA076140" Supported Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA076140: " "unprognostic (2.86e-3)" "unprognostic (7.63e-4)" "unprognostic (2.00e-1)" "unprognostic (3.52e-3)" "unprognostic (5.42e-2)" "unprognostic (1.14e-1)" "unprognostic (5.65e-2)" "unprognostic (2.38e-2)" "unprognostic (2.14e-1)" "unprognostic (3.16e-2)" "unprognostic (3.90e-1)" "unprognostic (1.66e-2)" "unprognostic (1.01e-9)" "unprognostic (6.87e-3)" "unprognostic (3.89e-2)" "unprognostic (3.13e-1)" "unprognostic (3.77e-3)" 0.3 0.5 5.6 0.1 8.6 0.0 0.3 0.0 11.7 0.8 0.0 1.3 0.0 1.2 0.2 0.3 0.7 0.2 5.3 28.4 0.0 0.2 0.1 0.7 0.0 0.0 0.0 0.7 0.4 0.0 1.2 0.1 0.0 0.5 0.0 1.2 0.4 0.5 1.2 0.5 0.2 0.7 0.0 0.1 0.3 0.6 0.3 0.1 0.2 0.2 0.0 0.5 0.6 0.0 0.0 0.0 0.3 0.3 0.3 1.5 0.1 0.8 0.5 0.4 0.5 0.0 0.0 0.4 1.4 2.2 0.1 0.1 0.0 0.4 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 3.2 0.0 4.6 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.8 0.8 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 7.4 0.1 0.2 0.1 14.4 0.2 0.2 6.5 0.0 0.0 0.0 8.9 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 8.6 0.0 11.7 28.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCED1B "FAM113B, MGC16044" ENSG00000179715 "PC-esterase domain containing 1B" Q96HM7 12 47079603-47236662 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 40.1;lymphoid tissue: 36.0" "Cell type enhanced" "Detected in many" "Astrocytes: 30.3;Excitatory neurons: 32.4;Granulosa cells: 47.8;Hofbauer cells: 37.6;Microglial cells: 60.0;T-cells: 36.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 63.3;K-562: 48.9;SK-BR-3: 31.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA043901 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 58: T-cells - T-cell receptor" "Golgi apparatus" Vesicles "HPA043901: AB_10959888" "unprognostic (1.71e-1)" "unprognostic (1.15e-1)" "unprognostic (3.29e-3)" "unprognostic (1.47e-3)" "unprognostic (2.72e-1)" "unprognostic (2.23e-1)" "unprognostic (3.32e-2)" "unprognostic (5.13e-2)" "unprognostic (2.36e-3)" "unprognostic (7.74e-2)" "unprognostic (3.39e-1)" "unprognostic (8.74e-2)" "prognostic unfavorable (4.55e-6)" "unprognostic (4.79e-2)" "unprognostic (3.74e-1)" "unprognostic (3.74e-2)" "prognostic favorable (5.36e-5)" 6.5 40.1 3.4 17.9 3.2 10.6 6.1 2.7 3.3 6.7 2.3 10.1 2.2 8.7 2.0 3.1 9.3 5.9 3.3 2.4 3.7 6.0 3.9 9.1 36.0 4.8 5.3 23.4 2.7 1.2 2.3 3.6 4.4 5.8 2.7 0.8 3.3 2.3 1.3 2.7 12.2 4.5 3.6 29.5 3.8 13.7 4.8 7.1 3.4 1.2 24.1 9.6 5.4 5.0 3.4 63.3 1.5 0.0 0.5 0.0 3.0 2.0 3.5 0.7 0.3 3.2 12.3 11.5 3.4 6.5 1.2 9.2 0.0 9.4 0.0 13.5 0.0 0.4 0.6 1.3 1.3 2.7 0.5 0.2 4.1 1.1 7.1 8.8 2.7 0.8 48.9 10.6 4.4 1.5 0.7 2.3 10.6 7.9 0.9 0.2 1.6 8.2 9.7 5.2 0.4 0.0 5.7 31.0 0.0 3.2 5.7 4.0 0.8 0.2 0.9 0.1 2.2 11.4 8.6 20.3 3.0 8.7 0.3 1.7 1.1 2.8 42.5 2.3 48.3 50.1 50.7 54.1 6.4 35.6 88.8 83.5 4.5 30.1 2.6 38.1 59.1 35.4 3.4 3.2 2.7 3.3 2.4 3.7 4.8 5.3 4.4 3.6 4.8 5.0 3.4 3.2 5.6 30.3 23.6 1.1 0.9 4.2 9.1 2.5 4.4 6.2 0.5 0.0 1.5 1.8 0.0 0.5 21.1 0.2 0.0 3.2 0.9 5.1 1.4 3.4 10.2 0.4 32.4 12.8 9.1 3.1 1.5 10.3 1.3 47.8 9.7 0.3 37.6 0.0 2.2 1.4 0.0 4.3 1.8 2.5 3.7 10.7 1.8 60.0 5.3 0.9 23.7 17.6 0.6 11.7 0.8 0.7 28.1 1.4 0.1 0.4 0.8 0.1 0.0 1.3 4.4 0.7 0.2 2.8 0.6 2.1 36.2 22.4 0.3 4.2 PCOLCE "PCPE, PCPE1" ENSG00000106333 "Procollagen C-endopeptidase enhancer" Q15113 7 100602363-100608175 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Endometrial stromal cells: 491.6;Fibroblasts: 439.9;Leydig cells: 140.5;Smooth muscle cells: 442.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 879.0;BJ hTERT+: 663.0;fHDF/TERT166: 404.5;HSkMC: 973.2;SH-SY5Y: 689.9;U-2197: 1213.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 81.1" "CAB017623, HPA042927" Approved Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 1300000000 "Cluster 22: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles" "CAB017623: AB_2251882, HPA042927: AB_2678224" "unprognostic (4.14e-1)" "unprognostic (1.79e-1)" "unprognostic (1.34e-1)" "unprognostic (2.92e-1)" "unprognostic (1.70e-2)" "unprognostic (4.48e-2)" "unprognostic (1.33e-2)" "unprognostic (3.93e-2)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.16e-2)" "unprognostic (1.73e-1)" "unprognostic (6.13e-2)" "prognostic unfavorable (1.68e-5)" "unprognostic (1.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.63e-2)" "unprognostic (1.43e-2)" 101.5 45.5 2.4 51.5 3.8 0.6 72.6 3.5 10.2 162.8 4.6 30.5 7.8 81.7 11.0 26.9 80.6 112.5 110.8 2.3 2.5 21.9 59.7 72.4 41.3 3.0 2.4 47.7 20.6 10.3 31.2 59.5 2.9 45.5 16.7 0.2 24.9 33.5 16.9 45.0 21.6 59.9 3.1 13.8 22.9 13.7 3.6 10.5 49.1 32.7 17.4 86.4 86.7 2.5 0.2 0.5 2.2 3.0 321.5 879.0 2.4 355.5 663.0 161.1 142.7 14.5 0.8 1.1 1.2 404.5 0.5 0.2 0.0 1.2 15.9 2.5 2.5 0.3 6.1 19.8 82.1 0.1 3.5 973.2 0.3 86.3 0.6 0.4 0.1 1.7 8.3 2.0 0.7 2.1 0.6 3.3 72.2 0.0 4.2 1.0 1.5 0.8 0.4 0.6 1.1 689.9 0.2 2.4 1.6 8.2 2.0 0.0 3.5 391.8 107.6 1213.4 0.2 0.4 0.5 0.1 136.6 1.2 68.2 0.0 0.0 0.4 0.1 0.3 0.3 0.1 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.4 0.2 0.0 0.1 0.0 2.4 3.8 3.5 10.2 2.3 2.5 3.0 2.4 2.9 3.1 3.6 2.5 33.6 9.6 2.8 2.3 2.5 40.0 3.3 4.2 6.8 4.3 6.6 11.3 16.3 4.3 5.5 5.5 0.0 13.3 4.5 0.8 27.4 6.4 14.8 15.1 491.6 17.2 1.8 5.7 0.5 5.1 11.2 439.9 7.1 11.0 1.3 0.7 33.9 44.8 20.8 16.8 2.5 0.9 6.1 1.9 53.6 27.6 140.5 5.5 32.0 9.4 0.8 12.1 6.2 1.5 0.2 4.1 1.3 50.4 2.1 2.2 0.1 2.5 6.8 2.0 32.9 14.2 442.2 32.8 21.0 3.6 33.1 25.2 9.4 22.6 0.7 3.0 PCP2 "GPSM4, MGC41903" ENSG00000174788 "Purkinje cell protein 2" Q8IVA1 19 7631611-7633719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 53.4;retina: 33.3;testis: 112.4" "Cell type enriched" "Detected in many" 4 "Late spermatids: 4139.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebellum: 53.4;white matter: 16.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 8.4;Karpas-707: 4.2;NB-4: 17.7" "Region enriched" "Detected in many" 44 "cerebellum: 2160.4" "Region enriched" "Detected in all" 28 "cerebellum: 552.9" HPA057428 Approved "Nuclear speckles,Vesicles" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear speckles" Vesicles "HPA057428: AB_2683436" "prognostic favorable (7.93e-4)" "unprognostic (6.06e-2)" "unprognostic (1.19e-2)" "unprognostic (4.43e-2)" "unprognostic (1.49e-1)" "unprognostic (1.79e-4)" "unprognostic (1.19e-1)" "unprognostic (4.88e-5)" "unprognostic (1.11e-1)" "unprognostic (6.23e-2)" "unprognostic (9.15e-3)" "unprognostic (6.01e-2)" "unprognostic (1.36e-2)" "unprognostic (8.17e-2)" "unprognostic (1.18e-1)" "unprognostic (8.70e-2)" "prognostic favorable (2.76e-5)" 0.4 1.6 0.4 1.1 0.6 3.7 5.5 53.4 2.3 2.1 0.0 0.6 1.4 0.9 3.3 2.0 2.4 2.3 2.2 0.5 0.0 8.0 3.7 2.2 3.0 0.1 3.5 0.1 5.4 1.1 1.4 0.4 5.5 5.9 0.3 33.3 16.3 1.9 0.2 7.0 1.6 0.0 0.1 3.0 3.1 112.4 0.0 3.1 5.7 0.0 1.4 0.9 1.6 16.8 1.8 0.4 0.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.7 1.6 0.7 1.1 0.0 0.0 1.3 0.0 0.2 0.0 0.8 0.6 2.6 2.8 0.1 0.0 0.3 8.4 0.0 0.6 0.0 0.0 0.0 0.0 0.7 0.2 4.2 0.0 0.3 0.3 17.7 0.4 0.3 0.0 0.8 0.2 0.7 0.8 0.1 0.1 0.0 1.4 1.4 0.0 0.4 3.7 3.4 0.2 0.0 0.5 0.4 0.0 1.4 0.7 0.2 0.0 2.0 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.1 0.1 0.1 0.2 0.3 0.2 0.3 0.8 0.2 0.0 0.6 0.0 1.7 0.4 0.6 53.4 2.3 0.5 0.0 0.1 3.5 5.5 0.1 0.0 16.8 0.1 0.0 2.3 0.0 0.2 0.8 1.1 1.4 0.0 734.7 7.7 5.8 0.0 2.8 1.8 5.5 22.9 0.2 2.7 0.7 9.8 0.8 836.5 1.0 0.1 2.6 0.0 0.0 0.0 0.2 0.1 0.1 0.0 1.5 1.3 1.3 0.0 0.5 0.4 23.5 0.0 0.4 0.0 0.8 1.3 4139.3 10.5 7.1 1.8 1.0 1.5 40.7 2.1 0.0 0.0 0.4 0.1 13.2 0.3 1.0 1.3 0.5 0.4 100.3 19.7 0.0 0.1 14.5 9.0 0.0 1.1 0.0 1.0 0.0 0.6 0.6 PCSK1N "BigLEN, PEN, proSAAS, SAAS, SCG8, SgVIII" ENSG00000102109 "Proprotein convertase subtilisin/kexin type 1 inhibitor" Q9UHG2 X 48831096-48835610 "Predicted secreted proteins" Neuropeptide "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 642.6;pituitary gland: 1243.7" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 3045.7;Horizontal cells: 437.4;Paneth cells: 628.8;Proximal tubular cells: 1601.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "MAIT T-cell: 2.4;memory CD4 T-cell: 5.0;memory CD8 T-cell: 4.9;naive CD4 T-cell: 2.0;naive CD8 T-cell: 6.4;T-reg: 1.8" "Lineage enriched" "Detected in single" 64 "T-cells: 6.4" "Cell line enhanced" "Detected in many" "HEK 293: 58.9;PC-3: 148.5;SCLC-21H: 58.2;SH-SY5Y: 53.8;SiHa: 52.1;U-266/84: 73.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003925, HPA064734" Enhanced Supported Approved Vesicles "Secreted to blood" NA NA 3300000 "Cluster 32: T-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA003925: AB_1079582, HPA064734: AB_2685339" "unprognostic (2.44e-3)" "unprognostic (5.86e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (3.36e-1)" "unprognostic (4.76e-3)" "unprognostic (1.49e-2)" "unprognostic (3.34e-1)" "unprognostic (5.63e-2)" "unprognostic (3.55e-1)" "unprognostic (1.50e-3)" "unprognostic (2.79e-3)" "prognostic favorable (1.36e-4)" "unprognostic (3.34e-2)" "unprognostic (2.91e-2)" "unprognostic (1.91e-1)" "unprognostic (2.14e-1)" 2.2 29.5 177.1 0.5 135.6 0.0 2.0 21.6 212.8 18.2 118.8 19.2 9.6 34.1 2.9 0.9 6.9 0.2 16.0 105.6 642.6 152.1 1.3 2.9 0.1 290.3 257.1 2.3 54.0 11.1 1243.7 0.2 193.0 14.4 0.5 2.5 6.7 0.8 0.8 8.8 13.7 0.6 95.5 1.1 21.9 19.7 264.9 0.0 3.3 0.0 0.0 1.2 6.5 51.8 0.1 5.4 0.2 14.9 0.6 0.0 0.4 0.0 0.0 0.0 0.0 5.3 0.1 0.0 10.4 0.0 4.2 0.8 0.0 1.1 0.0 0.0 58.9 0.0 0.0 9.3 0.0 0.0 3.7 0.0 0.8 0.0 0.0 2.2 0.0 0.0 0.0 0.2 0.0 7.6 0.0 0.5 7.9 0.0 148.5 0.0 0.0 0.4 1.4 0.2 58.2 53.8 52.1 0.2 4.9 0.7 0.2 0.1 0.1 0.1 22.7 0.2 5.0 13.3 73.6 0.3 0.4 0.0 1.5 0.0 0.0 0.0 0.8 0.0 2.4 0.0 5.0 4.9 0.0 0.0 2.0 6.4 0.0 0.0 0.0 0.0 1.8 0.7 177.1 135.6 21.6 212.8 105.6 642.6 290.3 257.1 193.0 95.5 264.9 51.8 0.8 0.0 0.0 29.0 12.5 15.8 1.3 4.3 0.6 139.6 11.4 14.9 1.4 2.8 4.3 389.9 52.1 1.0 1.0 18.2 277.8 8.6 12.8 44.3 8.7 3.6 3045.7 2.7 64.8 0.7 69.0 17.2 112.1 35.2 0.0 2.5 0.0 0.5 1.7 437.4 118.8 218.9 54.9 0.3 17.2 52.9 3.4 10.5 56.9 22.5 0.4 96.2 1.0 72.9 26.0 23.1 628.8 7.2 4.5 30.4 21.6 1601.1 24.8 148.2 0.0 0.3 12.6 32.5 82.2 0.2 11.5 1.9 20.1 0.2 15.6 3.7 PCSK2 "NEC2, PC2, SPC2" ENSG00000125851 "Proprotein convertase subtilisin/kexin type 2" P16519 20 17226107-17484578 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 28.5;brain: 30.2;retina: 35.8;thyroid gland: 56.9" "Cell type enhanced" "Detected in many" "Early spermatids: 87.3;Excitatory neurons: 322.8;Horizontal cells: 132.9;Inhibitory neurons: 148.8;Melanocytes: 209.9;Muller glia cells: 452.7" "Cancer enriched" "Detected in many" 4 "thyroid cancer: 65.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 60.0;SCLC-21H: 15.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049627 Approved Approved Vesicles "Secreted in other tissues" NA NA 18000 "Cluster 41: Basophils - Cellular respiration" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA049627: AB_2680835" "unprognostic (2.03e-3)" "unprognostic (1.61e-1)" "unprognostic (3.13e-1)" "unprognostic (2.18e-1)" "unprognostic (2.13e-1)" "unprognostic (6.84e-2)" "unprognostic (3.07e-3)" "unprognostic (4.31e-1)" "unprognostic (5.88e-2)" "unprognostic (2.50e-3)" "unprognostic (2.14e-1)" "unprognostic (7.26e-5)" "unprognostic (2.29e-1)" "unprognostic (1.57e-1)" "unprognostic (2.35e-1)" "unprognostic (1.14e-1)" 0.7 28.5 8.6 0.8 14.9 0.5 0.4 0.1 30.2 1.6 0.0 6.9 4.8 0.2 0.3 1.1 1.0 0.5 4.7 15.8 11.1 0.2 0.2 2.5 0.0 2.2 1.3 9.0 19.8 0.8 2.0 0.6 2.6 1.4 1.7 35.8 1.7 1.2 0.1 14.1 2.1 0.4 1.4 0.1 8.1 4.8 13.2 0.0 56.9 0.1 0.1 3.0 2.4 11.9 0.0 0.0 60.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.2 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 14.9 0.1 30.2 15.8 11.1 2.2 1.3 2.6 1.4 13.2 11.9 0.1 0.0 7.3 7.8 0.0 8.2 0.0 0.0 1.2 28.1 0.0 0.0 1.2 0.0 0.6 0.0 6.2 0.0 0.0 0.0 0.0 0.0 87.3 0.0 0.0 1.3 0.0 0.0 322.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 4.6 0.0 0.0 132.9 148.8 0.6 0.0 0.0 1.3 6.3 2.8 0.2 209.9 8.4 0.0 452.7 0.0 44.7 6.4 2.8 2.5 0.0 0.0 0.0 0.0 0.0 0.0 14.4 0.0 0.5 1.2 1.0 0.3 0.2 1.4 0.0 0.1 0.6 0.0 0.1 PDCD11 "ALG-4, KIAA0185, NFBP, RRP5" ENSG00000148843 "Programmed cell death 11" Q14690 10 103396626-103446294 "Plasma proteins, Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 61.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017924, CAB026472" Approved Supported "Nucleoli rim,Vesicles" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoli rim" Vesicles "CAB026472: , HPA017924: AB_10601045" "unprognostic (1.34e-1)" "unprognostic (6.84e-2)" "unprognostic (1.48e-1)" "unprognostic (2.31e-2)" "unprognostic (1.80e-1)" "unprognostic (8.94e-2)" "prognostic unfavorable (2.79e-4)" "unprognostic (2.11e-1)" "unprognostic (1.89e-1)" "unprognostic (1.16e-1)" "unprognostic (6.49e-2)" "unprognostic (3.25e-2)" "unprognostic (9.29e-2)" "unprognostic (1.01e-2)" "unprognostic (1.77e-1)" "unprognostic (6.28e-2)" "unprognostic (5.59e-2)" 8.1 7.8 4.1 10.0 4.8 7.5 9.4 4.5 4.6 8.7 4.5 7.7 5.9 9.9 5.9 11.7 9.0 4.4 7.5 4.4 4.7 9.8 9.1 7.3 11.0 4.4 4.5 10.4 11.6 8.5 6.4 7.5 4.6 8.0 7.9 6.1 7.2 6.2 15.8 15.5 7.7 9.1 4.1 9.5 7.3 14.8 5.1 11.9 6.9 8.1 11.8 9.9 8.4 5.0 27.4 39.8 27.2 77.0 23.3 20.9 30.5 29.6 20.7 29.2 23.7 54.7 26.3 74.9 20.5 21.4 18.0 48.0 70.6 37.1 32.5 34.8 47.5 43.7 26.0 44.2 27.7 88.0 28.7 21.8 33.3 44.8 101.3 21.0 31.6 19.4 71.5 32.7 28.4 30.9 44.5 49.9 55.9 21.7 37.9 44.3 39.0 34.1 18.1 26.6 18.2 34.1 19.9 23.2 32.6 26.4 22.8 24.8 34.5 21.5 27.0 29.0 55.9 41.2 61.8 69.5 19.0 83.3 16.2 0.1 2.8 0.9 3.2 2.6 5.2 3.4 3.1 2.7 2.8 2.2 2.7 3.2 0.3 2.1 2.3 3.3 2.3 2.5 4.1 4.8 4.5 4.6 4.4 4.7 4.4 4.5 4.6 4.1 5.1 5.0 8.8 12.8 14.1 5.9 13.6 16.4 9.3 10.8 8.0 15.0 18.6 15.6 14.6 20.0 17.4 9.2 29.2 12.8 18.1 9.6 13.7 23.6 61.2 12.6 25.4 14.4 9.5 14.9 11.8 15.8 15.8 14.0 5.6 11.7 18.9 18.5 8.9 24.5 10.9 6.7 9.3 12.9 4.1 7.7 5.2 19.6 11.1 10.7 10.6 8.4 9.8 4.9 9.2 7.5 7.6 29.1 4.9 10.1 9.6 17.9 4.4 8.2 20.2 13.8 6.6 16.8 11.0 27.5 30.7 14.0 16.9 8.2 11.6 19.0 19.9 8.7 PDCD6IP "AIP1, Alix, Hp95" ENSG00000170248 "Programmed cell death 6 interacting protein" Q8WUM4 3 33798571-33869707 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 299.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA011905, CAB016212, HPA051604" Approved Approved Vesicles,Centrosome "Intracellular and membrane" NA NA 4100000 "Cluster 27: Non-specific - Gene expression" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles Centrosome "CAB016212: AB_673819, HPA011905: AB_1855111, HPA051604: " "unprognostic (1.53e-1)" "unprognostic (2.63e-1)" "prognostic favorable (1.16e-4)" "unprognostic (2.17e-1)" "unprognostic (2.75e-1)" "unprognostic (5.12e-2)" "unprognostic (7.76e-3)" "unprognostic (1.23e-2)" "unprognostic (3.29e-1)" "unprognostic (2.86e-1)" "unprognostic (3.88e-3)" "unprognostic (4.49e-2)" "prognostic favorable (3.90e-9)" "unprognostic (9.61e-2)" "unprognostic (1.89e-1)" "unprognostic (4.78e-1)" "unprognostic (1.11e-1)" 33.1 27.6 16.3 24.5 17.9 21.2 32.9 18.4 23.3 35.0 23.0 46.4 36.2 35.1 26.4 46.0 30.9 25.9 30.5 17.6 19.7 35.0 33.2 35.2 26.1 25.2 18.1 34.3 25.0 40.6 22.8 31.2 26.4 30.0 41.5 30.5 29.7 23.7 33.9 39.8 38.8 31.8 18.6 27.5 37.2 23.8 18.8 24.4 34.2 22.1 30.1 26.9 35.9 21.4 47.2 46.4 30.2 25.1 78.5 80.6 34.3 67.2 56.2 50.9 52.2 33.3 43.8 75.9 33.8 77.7 32.2 45.5 47.8 61.4 57.8 27.4 39.5 56.7 37.4 28.2 50.8 56.5 57.6 62.2 69.5 57.6 67.8 60.5 77.1 32.4 50.3 26.2 74.4 27.0 36.3 31.8 29.9 43.5 57.8 32.8 36.5 43.8 64.6 39.2 14.7 26.8 61.6 67.8 30.7 48.9 62.0 51.4 101.1 59.5 28.2 50.1 46.9 26.6 37.6 55.6 56.7 62.6 28.8 6.8 13.5 11.0 8.0 18.1 8.7 12.0 8.9 8.1 12.4 10.8 7.7 7.5 6.8 12.1 18.0 5.0 9.4 10.0 16.3 17.9 18.4 23.3 17.6 19.7 25.2 18.1 26.4 18.6 18.8 21.4 78.5 86.6 84.8 85.8 76.1 41.7 62.6 62.7 51.8 28.6 42.5 34.0 53.4 62.9 80.6 64.4 52.1 53.0 58.5 299.9 37.2 67.2 85.3 121.6 84.0 68.8 36.1 40.6 83.5 78.3 52.8 54.3 96.8 77.8 53.7 53.0 54.3 57.3 60.6 25.2 69.2 97.1 63.1 93.0 44.7 50.4 74.0 85.0 28.4 75.9 71.0 23.1 42.2 96.0 161.7 122.5 127.1 80.5 46.9 56.5 130.2 61.0 130.9 49.9 46.0 42.3 50.4 93.0 48.4 61.5 43.2 96.6 55.2 47.7 86.7 70.3 PDE6G "PDEG, RP57" ENSG00000185527 "Phosphodiesterase 6G" P18545 17 81650459-81663112 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 99 "retina: 2050.3" "Cell type enriched" "Detected in many" 6 "Rod photoreceptor cells: 4448.6" "Cancer enhanced" "Detected in many" "testis cancer: 10.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "basophil: 127.0;NK-cell: 220.2" "Group enriched" "Detected in all" 6 "granulocytes: 127.0;NK-cells: 220.2" "Cell line enhanced" "Detected in some" "Hep G2: 5.2;NB-4: 5.8;NTERA-2: 8.9;REH: 11.9;SuSa: 6.2" "Region enhanced" "Detected in some" "hippocampal formation: 4.7" "Not detected" "Not detected" HPA045118 Supported Uncertain Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 5: NTERA-2 - Transcription" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles "HPA045118: AB_2732517" "unprognostic (6.16e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "unprognostic (3.51e-3)" "unprognostic (1.68e-1)" "unprognostic (1.46e-2)" "unprognostic (6.33e-2)" "unprognostic (3.80e-2)" "unprognostic (1.10e-2)" "unprognostic (1.02e-1)" "unprognostic (4.85e-2)" "unprognostic (5.01e-2)" "unprognostic (1.94e-2)" "unprognostic (5.71e-2)" "unprognostic (5.44e-2)" "unprognostic (2.73e-1)" "unprognostic (1.14e-1)" 1.5 0.3 0.0 4.7 0.1 7.8 0.9 0.2 0.5 1.0 0.2 1.6 0.6 0.2 0.1 0.8 0.7 2.5 0.4 0.1 0.7 2.1 4.2 3.0 20.6 0.1 0.2 0.0 0.0 0.1 0.1 12.0 0.2 0.2 1.0 2050.3 0.5 0.4 1.2 0.3 1.6 0.9 0.1 19.9 1.7 0.8 0.3 8.3 0.4 0.3 7.1 3.0 0.1 0.2 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.3 0.1 0.2 0.0 0.9 0.0 0.0 0.0 0.0 5.2 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.4 2.8 0.2 0.1 0.2 0.4 0.3 0.0 5.8 8.9 0.0 0.0 11.9 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.1 0.1 6.2 0.1 0.8 1.2 0.2 0.0 0.0 0.1 0.1 0.6 0.9 0.4 3.1 0.1 127.0 18.1 30.5 4.1 26.2 1.3 2.7 0.8 2.3 28.9 5.1 2.1 7.4 2.4 220.2 15.5 2.9 0.1 13.5 0.0 0.1 0.2 0.5 0.1 0.7 0.1 0.2 0.2 0.1 0.3 0.2 0.3 0.0 0.6 0.3 1.1 0.9 0.0 0.0 0.6 422.5 0.3 0.4 0.2 0.0 0.0 5.5 517.1 0.2 4.3 0.1 1.9 0.4 0.8 1.5 0.3 27.2 0.0 1.7 0.2 0.2 0.4 0.2 0.0 0.5 23.6 0.1 2.9 0.2 22.6 262.5 0.1 0.2 0.0 4.8 8.0 2.3 0.0 4.4 3.6 0.0 13.3 709.0 11.3 0.0 0.1 0.2 0.0 0.0 0.8 0.1 0.1 1.0 0.0 4448.6 0.0 0.1 0.1 1.1 0.2 0.3 1.4 0.3 1.7 2.1 0.0 0.1 PDE6H ENSG00000139053 "Phosphodiesterase 6H" Q13956 12 14973042-14981865 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 226 "retina: 911.3" "Group enriched" "Detected in some" 6 "Cone photoreceptor cells: 831.9;Rod photoreceptor cells: 218.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "AN3-CA: 1.0" "Low region specificity" "Detected in single" HPA045118 Supported Uncertain Vesicles NA NA "Cluster 79: Retina - Phototransduction" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "HPA045118: AB_2732517" "unprognostic (1.47e-3)" "unprognostic (1.07e-2)" 0.0 0.4 0.3 0.0 0.4 4.0 0.0 0.1 1.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.1 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 911.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.4 0.1 1.0 0.3 2.3 0.3 0.4 0.5 0.2 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 62.9 0.0 0.0 0.1 0.0 0.0 0.0 831.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.5 0.0 21.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 23.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.5 0.0 0.0 0.6 81.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 218.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 PDGFB "SIS, SSV" ENSG00000100311 "Platelet derived growth factor subunit B" P01127 22 39223359-39244982 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 75.0;Endothelial cells: 60.6;Langerhans cells: 44.3;Macrophages: 25.5;Pancreatic endocrine cells: 54.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.0" "Lineage enriched" "Detected in many" 7 "T-cells: 10.0" "Cell line enhanced" "Detected in many" "A-431: 33.8;EFO-21: 69.2;HUVEC TERT2: 52.6;SK-BR-3: 53.5;TIME: 68.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011604, HPA011972, CAB018341" Supported Approved Vesicles "Secreted to blood" NA NA 4390000 950000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB011604: AB_2162180, CAB018341: AB_2162187, HPA011972: AB_1855134" "unprognostic (4.96e-2)" "unprognostic (8.94e-3)" "unprognostic (8.41e-2)" "unprognostic (2.66e-1)" "unprognostic (9.84e-2)" "unprognostic (4.46e-3)" "unprognostic (4.34e-1)" "prognostic unfavorable (3.67e-5)" "unprognostic (3.22e-2)" "unprognostic (2.07e-1)" "unprognostic (1.05e-1)" "unprognostic (8.68e-2)" "unprognostic (1.84e-3)" "unprognostic (5.12e-3)" "unprognostic (7.47e-2)" "unprognostic (6.50e-2)" "unprognostic (1.03e-1)" 32.6 6.4 14.7 7.1 10.7 0.4 24.0 10.3 22.2 7.5 4.8 20.6 4.9 8.9 5.2 6.2 7.2 11.7 31.2 12.0 9.8 17.0 3.7 28.1 7.4 13.6 12.4 3.8 8.8 8.9 4.0 40.2 12.0 7.6 3.5 0.8 10.6 5.2 18.7 10.3 9.1 9.2 10.6 6.6 7.9 3.4 16.0 2.1 16.1 11.0 1.6 8.5 6.6 9.4 33.8 2.6 8.4 0.0 0.0 0.0 9.9 0.1 0.4 0.2 0.0 13.0 10.3 0.0 69.2 0.0 3.1 12.4 0.5 2.8 0.0 0.1 0.2 0.7 1.1 4.8 4.3 0.0 18.1 0.0 0.3 0.0 0.4 0.9 52.6 0.0 1.3 6.1 1.9 13.7 0.1 0.1 3.2 8.1 3.4 0.0 0.3 22.8 27.7 0.1 0.2 0.0 0.6 53.5 0.2 6.0 24.3 0.1 68.1 0.1 6.4 0.1 7.5 0.1 0.4 0.3 0.1 1.5 31.3 0.0 0.0 0.0 7.3 0.1 10.0 0.0 4.3 5.6 0.0 0.0 3.6 1.9 0.1 0.0 0.4 1.3 2.3 2.1 14.7 10.7 10.3 22.2 12.0 9.8 13.6 12.4 12.0 10.6 16.0 9.4 75.0 0.0 1.1 0.0 0.6 2.8 1.2 3.8 1.2 0.7 5.1 7.1 3.1 0.0 1.3 7.3 0.0 7.3 4.0 0.1 0.0 20.0 1.3 4.0 0.7 60.6 1.8 0.0 2.8 3.6 6.5 1.6 0.0 5.6 0.0 13.1 16.8 1.4 7.7 0.0 0.9 0.7 4.1 2.6 44.3 0.1 0.6 25.5 1.8 14.0 1.1 0.3 0.0 0.0 0.2 54.7 0.0 0.0 0.0 2.7 0.1 1.9 0.9 0.1 6.6 4.7 9.6 0.3 1.6 1.1 1.4 4.5 2.0 1.2 0.1 0.6 PDGFD "IEGF, MSTP036, SCDGF-B" ENSG00000170962 "Platelet derived growth factor D" Q9GZP0 11 103907189-104164379 "Predicted intracellular proteins, Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 106.5;ovary: 78.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 32.9;dendritic cells: 30.0;Ductal cells: 30.6;Fibroblasts: 44.3;Inhibitory neurons: 95.0;Microglial cells: 28.1;NK-cells: 46.4" "Cancer enhanced" "Detected in all" "renal cancer: 17.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "eosinophil: 9.5;gdT-cell: 16.4;memory CD8 T-cell: 7.2;naive CD8 T-cell: 6.0;NK-cell: 17.1" "Group enriched" "Detected in many" 29 "granulocytes: 9.5;NK-cells: 17.1;T-cells: 16.4" "Group enriched" "Detected in many" 6 "ASC diff: 139.8;HHSteC: 42.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 39.4" "HPA046183, HPA066271" Approved Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 95000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus, Vesicles" "HPA046183: AB_2679573, HPA066271: AB_2685645" "unprognostic (2.21e-1)" "unprognostic (9.35e-2)" "unprognostic (5.60e-2)" "unprognostic (1.72e-1)" "unprognostic (5.81e-2)" "unprognostic (8.83e-2)" "unprognostic (2.14e-2)" "unprognostic (1.63e-1)" "unprognostic (2.66e-1)" "unprognostic (1.01e-1)" "unprognostic (6.78e-2)" "unprognostic (2.26e-1)" "unprognostic (7.01e-3)" "prognostic unfavorable (9.60e-4)" "unprognostic (1.19e-1)" "unprognostic (6.72e-2)" "unprognostic (3.57e-3)" 20.4 106.5 0.5 3.4 0.8 0.9 21.7 0.7 1.3 25.1 9.0 8.8 4.1 11.8 7.1 1.9 9.3 34.0 23.2 0.8 2.2 7.7 2.3 3.1 7.4 5.1 6.6 78.0 25.7 17.1 13.4 7.0 9.4 10.0 9.8 1.5 8.6 37.4 2.2 7.9 4.8 9.7 1.8 2.8 23.4 3.3 2.0 3.7 18.3 8.8 5.4 15.8 15.4 2.3 0.0 7.8 4.0 0.0 139.8 4.2 0.1 0.9 0.8 0.7 0.8 0.0 1.3 7.4 1.4 7.3 5.2 0.4 0.0 0.2 0.3 0.0 3.2 0.2 1.6 0.3 42.6 0.0 0.1 14.7 0.0 0.1 0.0 0.2 8.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.3 0.0 1.4 0.0 2.1 0.0 6.7 0.0 0.1 9.6 0.0 13.8 3.2 1.8 0.0 2.0 1.0 0.1 1.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.8 0.6 0.0 9.5 16.4 0.0 1.4 0.4 1.7 7.2 0.0 0.0 0.2 6.0 0.2 17.1 0.1 0.0 0.1 4.2 0.5 0.8 0.7 1.3 0.8 2.2 5.1 6.6 9.4 1.8 2.0 2.3 15.6 0.0 0.0 1.0 1.6 3.1 7.7 0.2 1.8 2.3 1.7 9.4 4.5 32.9 0.6 5.5 0.0 0.2 30.0 0.2 0.0 30.6 8.2 0.8 1.8 10.3 1.8 1.3 13.9 4.4 0.2 44.3 0.0 1.4 0.0 8.1 2.9 0.0 0.3 26.9 95.0 1.0 0.0 1.3 3.7 13.3 0.3 0.8 0.0 28.1 0.9 1.5 46.4 2.0 2.8 3.0 0.5 2.2 8.4 1.6 0.0 0.3 0.0 0.5 6.6 1.9 3.7 0.4 4.3 0.3 2.0 0.0 10.2 5.2 0.6 3.2 PDGFRB "CD140b, JTK12, PDGFR, PDGFR1" ENSG00000113721 "Platelet derived growth factor receptor beta" P09619 5 150113839-150155872 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" Chemotaxis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Sertoli cells: 1288.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "ASC diff: 1350.1;ASC TERT1: 462.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003842, CAB018144, HPA028499" Enhanced Supported "Golgi apparatus,Vesicles" NA NA 39000000 "Cluster 14: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "Golgi apparatus" "CAB003842: AB_562328, CAB018144: AB_2162497, HPA028499: AB_10602018" "unprognostic (4.75e-2)" "unprognostic (2.48e-1)" "unprognostic (5.21e-2)" "unprognostic (3.60e-2)" "unprognostic (3.27e-1)" "unprognostic (5.61e-2)" "unprognostic (1.02e-1)" "unprognostic (3.36e-2)" "unprognostic (2.12e-2)" "unprognostic (2.57e-3)" "unprognostic (6.72e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (5.87e-8)" "unprognostic (3.13e-3)" "unprognostic (1.25e-2)" "unprognostic (5.47e-2)" "prognostic unfavorable (8.11e-4)" 171.2 25.1 25.4 27.5 27.2 0.7 106.3 20.5 33.3 155.9 43.5 41.6 11.9 101.1 24.2 24.1 89.6 124.5 75.7 22.1 23.2 49.7 13.4 98.3 27.5 22.1 24.6 105.5 20.8 21.9 23.0 113.3 22.8 56.2 14.1 6.3 34.5 43.3 38.1 65.0 37.9 68.9 19.4 41.4 27.9 18.4 27.7 8.7 66.5 44.1 13.8 58.3 98.6 21.6 0.1 0.3 8.3 0.4 1350.1 462.7 3.0 48.9 202.3 33.5 56.4 5.4 0.0 0.0 6.4 142.0 19.0 0.1 0.1 0.4 15.8 0.0 0.0 0.1 3.3 3.5 190.7 0.0 0.4 210.0 0.0 46.3 0.6 106.6 0.1 0.1 0.1 5.5 5.5 0.0 0.1 0.6 9.0 0.2 0.2 3.7 2.5 0.2 0.0 0.0 0.1 24.8 0.5 0.1 0.0 38.2 0.1 0.6 0.4 53.7 17.2 23.1 2.8 0.4 0.0 0.3 33.4 0.1 1.5 0.0 0.0 0.0 0.9 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 1.6 0.0 0.0 0.2 25.4 27.2 20.5 33.3 22.1 23.2 22.1 24.6 22.8 19.4 27.7 21.6 50.8 0.0 1.1 81.9 0.5 24.0 0.5 0.0 2.2 6.6 1.4 3.3 17.3 1.5 0.0 1.8 4.2 0.6 6.0 0.3 0.0 0.8 1.6 2.8 99.5 32.2 0.0 0.0 7.9 0.0 1.1 123.5 2.0 2.3 0.0 2.5 6.4 1.9 1.5 0.0 1.3 0.7 0.0 0.0 35.6 10.9 165.3 3.1 24.9 45.0 0.7 50.7 23.7 10.1 3.3 0.1 0.1 203.8 2.3 0.7 0.3 0.1 0.7 2.9 1288.5 6.6 288.3 1.9 1.6 0.8 15.3 0.8 4.8 4.0 0.4 1.1 PDXDC1 KIAA0251 ENSG00000179889 "Pyridoxal dependent decarboxylase domain containing 1" Q6P996 16 14974591-15139339 "Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 483.6;Late spermatids: 733.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 121.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047369, HPA049121, HPA051484" Approved Enhanced "Golgi apparatus,Vesicles" NA NA 9600 "Cluster 39: Non-specific - mRNA processing" "Cluster 71: Testis - DNA repair" "Cluster 6: T47d - Mammary gland" "Cluster 34: Spermatids - Unknown function" "Golgi apparatus, Vesicles" "HPA047369: AB_2680015, HPA049121: AB_2680641, HPA051484: AB_2681502" "unprognostic (3.67e-2)" "unprognostic (4.99e-1)" "unprognostic (1.97e-3)" "unprognostic (1.84e-1)" "unprognostic (9.08e-2)" "unprognostic (2.18e-1)" "unprognostic (6.47e-3)" "unprognostic (4.97e-2)" "unprognostic (2.43e-1)" "unprognostic (2.74e-1)" "unprognostic (7.61e-2)" "unprognostic (1.32e-1)" "prognostic favorable (3.13e-4)" "unprognostic (4.58e-2)" "unprognostic (8.11e-2)" "unprognostic (2.15e-1)" "unprognostic (2.88e-1)" 33.3 37.9 4.9 20.9 5.0 12.9 33.1 14.7 6.5 35.7 7.9 61.3 52.5 31.9 17.0 43.4 29.2 20.8 39.1 6.0 4.1 47.6 104.5 34.6 13.4 6.2 4.7 31.1 70.4 27.1 63.2 23.5 7.5 55.8 47.8 13.4 80.5 25.2 52.0 27.8 61.1 18.5 1.2 31.8 56.7 113.2 7.2 11.7 42.9 16.5 15.0 39.1 34.7 5.7 21.4 30.9 31.1 26.1 16.9 20.4 51.4 19.6 17.4 14.3 19.7 38.0 45.3 40.7 42.0 26.5 20.5 34.0 22.1 20.1 20.5 25.0 30.2 24.7 51.8 100.2 44.3 19.7 56.4 21.5 20.4 25.0 20.9 28.0 15.3 21.6 18.5 26.0 34.1 52.2 12.9 10.4 15.3 20.8 11.7 19.9 12.9 48.6 22.7 33.9 31.9 22.8 52.6 30.0 50.9 19.7 121.0 30.3 23.8 11.0 10.0 12.3 25.7 24.2 25.1 39.3 22.7 16.4 35.8 2.9 7.8 11.6 9.4 7.7 10.8 8.3 6.8 7.7 11.7 9.0 8.2 8.1 1.0 7.5 6.2 5.4 6.6 8.2 4.9 5.0 14.7 6.5 6.0 4.1 6.2 4.7 7.5 1.2 7.2 5.7 29.6 38.5 64.6 32.7 33.0 38.2 42.2 21.6 18.8 32.1 57.9 27.8 45.7 58.6 52.9 29.5 31.3 51.7 30.6 149.8 27.4 38.2 483.6 48.1 41.7 35.1 161.2 33.2 80.7 58.3 56.5 36.0 71.9 75.3 39.3 42.1 27.5 123.6 30.5 40.4 68.3 216.7 24.4 33.1 16.8 733.8 49.0 30.9 26.6 31.9 27.5 19.7 39.1 55.8 45.0 46.5 114.4 45.5 45.4 58.1 115.6 53.4 48.3 47.4 46.0 24.0 28.0 142.3 72.7 24.6 42.6 80.7 33.9 21.2 127.2 76.5 PDZK1 "NHERF3, PDZD1" ENSG00000174827 "PDZ domain containing 1" Q5T2W1 1 145670852-145708148 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 595.8" "Group enriched" "Detected in many" 5 "Proximal enterocytes: 280.0;Proximal tubular cells: 1113.8" "Group enriched" "Detected in many" 4 "liver cancer: 27.6;renal cancer: 44.3" "Region enriched" "Detected in many" 7 "cerebellum: 14.7" "Immune cell enriched" "Detected in single" 5 "NK-cell: 4.2" "Lineage enriched" "Detected in single" 5 "NK-cells: 4.2" "Group enriched" "Detected in many" 4 "RPTEC TERT1: 250.0;T-47d: 653.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA005755, HPA006155, CAB008971" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Vesicles" Cytosol "CAB008971: , HPA005755: AB_1855164, HPA006155: AB_1855163" "unprognostic (4.56e-3)" "unprognostic (3.07e-1)" "unprognostic (8.79e-2)" "unprognostic (4.41e-2)" "unprognostic (9.15e-2)" "unprognostic (2.09e-1)" "unprognostic (2.18e-1)" "unprognostic (3.42e-1)" "unprognostic (2.08e-1)" "unprognostic (3.27e-1)" "unprognostic (2.34e-2)" "unprognostic (9.87e-3)" "prognostic favorable (2.54e-7)" "unprognostic (9.90e-2)" "unprognostic (3.02e-1)" "unprognostic (1.00e-3)" "unprognostic (8.87e-2)" 0.6 3.5 0.7 0.5 0.9 0.6 19.6 14.7 2.0 2.4 1.9 4.7 74.8 0.7 15.8 0.2 1.0 22.0 0.4 1.0 0.5 595.8 128.1 0.3 0.7 1.4 0.8 0.3 16.6 0.0 0.6 0.5 1.8 0.3 8.2 3.0 0.4 0.8 0.3 2.6 124.9 0.8 0.4 0.7 2.8 0.6 0.8 0.3 0.3 0.1 0.2 0.2 0.3 1.5 7.6 1.2 0.8 0.8 0.3 0.4 3.0 1.2 0.3 0.2 1.0 106.6 1.0 0.7 1.3 5.9 0.5 3.4 0.2 0.6 0.6 10.3 2.0 0.9 2.8 45.7 0.0 1.1 0.9 0.3 0.7 0.4 0.2 0.8 0.0 0.4 0.8 1.6 0.8 6.0 0.7 1.4 1.2 1.5 3.6 0.4 7.3 1.6 250.0 0.3 0.6 6.7 1.7 1.8 0.2 6.4 653.8 0.9 0.5 1.3 1.3 0.9 1.1 8.8 1.2 0.6 1.0 0.6 0.5 0.1 0.1 0.0 0.7 0.1 0.2 0.6 0.2 0.8 0.0 0.4 0.2 0.3 0.1 4.2 0.0 0.5 0.0 0.3 0.7 0.9 14.7 2.0 1.0 0.5 1.4 0.8 1.8 0.4 0.8 1.5 0.2 0.0 0.0 2.0 4.1 0.1 0.0 0.1 0.0 0.4 20.2 3.3 0.5 72.9 0.0 57.0 0.0 0.0 0.9 27.4 138.9 1.2 8.6 1.1 0.5 0.4 6.6 0.0 2.8 2.0 0.1 0.5 0.5 4.9 0.0 0.2 1.1 47.9 0.2 0.0 1.9 7.8 0.0 0.9 0.3 9.0 0.0 4.9 0.0 1.9 0.0 0.3 2.1 3.0 0.7 1.5 7.4 0.0 0.0 0.1 280.0 1113.8 0.1 0.5 0.0 0.1 0.3 0.2 0.3 0.0 0.0 0.1 4.1 4.3 6.5 0.1 PEF1 PEF1A ENSG00000162517 "Penta-EF-hand domain containing 1" Q9UBV8 1 31629866-31644896 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 182.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061608 Supported Nucleoplasm,Vesicles,Cytosol NA NA 570000 "Cluster 2: Granulocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Vesicles, Cytosol" "HPA061608: AB_2684567" "unprognostic (2.92e-2)" "prognostic favorable (3.95e-4)" "unprognostic (1.59e-1)" "unprognostic (2.30e-2)" "unprognostic (1.11e-1)" "unprognostic (8.40e-2)" "prognostic unfavorable (2.88e-4)" "unprognostic (5.22e-3)" "unprognostic (1.04e-1)" "unprognostic (2.79e-2)" "unprognostic (1.60e-2)" "unprognostic (2.12e-1)" "unprognostic (1.35e-1)" "unprognostic (8.85e-3)" "unprognostic (2.38e-1)" "unprognostic (1.60e-1)" "unprognostic (2.89e-3)" 57.3 67.1 76.4 28.5 78.6 37.9 56.4 80.1 81.3 56.3 77.8 59.0 31.3 63.3 84.4 62.1 54.6 38.6 63.8 77.9 81.6 69.4 71.3 61.3 38.5 81.9 78.6 50.2 40.9 69.1 52.1 61.4 84.7 59.4 45.1 26.6 39.9 59.1 42.5 85.7 44.0 60.0 79.9 55.9 51.3 40.1 78.9 56.6 110.9 39.3 61.6 61.9 52.2 81.4 56.9 65.0 53.1 41.3 61.2 63.8 51.0 52.8 89.8 124.4 109.0 38.7 83.2 60.2 71.9 118.3 63.9 58.1 103.9 134.5 100.1 76.0 112.6 49.9 49.4 78.6 107.9 49.0 45.3 66.3 152.6 122.0 113.2 79.2 122.2 72.6 52.4 60.6 90.4 67.1 75.6 47.5 74.3 69.7 72.9 72.5 51.7 66.2 98.6 60.8 75.8 43.9 60.2 56.1 81.0 82.9 50.0 35.5 65.7 54.0 46.0 92.7 71.3 38.7 42.2 65.4 67.7 71.8 65.9 147.3 75.6 93.0 90.2 69.4 86.8 70.9 75.5 81.4 77.5 76.4 70.2 70.6 76.2 87.4 67.2 71.4 84.0 104.8 76.4 78.6 80.1 81.3 77.9 81.6 81.9 78.6 84.7 79.9 78.9 81.4 58.2 41.7 37.7 5.9 31.6 36.2 66.6 70.8 29.6 41.2 34.7 36.2 20.4 21.5 35.3 69.9 12.5 160.0 33.9 36.6 113.5 72.0 81.3 17.4 20.0 60.3 44.3 40.0 8.0 61.9 106.1 34.0 21.9 19.8 72.9 34.3 35.3 24.4 61.9 53.8 7.4 49.8 50.8 18.5 21.8 87.5 45.1 27.8 49.8 7.5 81.6 59.6 46.4 6.0 13.8 59.1 44.0 58.6 23.6 65.4 48.9 57.8 23.5 26.5 19.7 25.8 38.8 44.1 44.2 24.6 51.4 182.8 33.6 50.9 39.5 58.3 PELI3 MGC35521 ENSG00000174516 "Pellino E3 ubiquitin protein ligase family member 3" Q8N2H9 11 66466327-66477337 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 26.5;Horizontal cells: 21.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033750, HPA038875, HPA062281" Uncertain Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Vesicles" Nucleoli "CAB033750: AB_2161361, HPA038875: AB_2676249, HPA062281: AB_2684735" "unprognostic (1.15e-1)" "unprognostic (1.58e-1)" "unprognostic (3.04e-1)" "unprognostic (1.43e-1)" "unprognostic (1.02e-2)" "unprognostic (1.89e-2)" "unprognostic (1.30e-2)" "unprognostic (1.94e-1)" "unprognostic (1.35e-1)" "unprognostic (1.19e-1)" "unprognostic (2.19e-3)" "unprognostic (7.91e-3)" "prognostic favorable (8.19e-4)" "unprognostic (1.59e-1)" "unprognostic (1.44e-1)" "unprognostic (1.91e-1)" "unprognostic (3.01e-2)" 7.5 10.2 19.1 2.6 18.7 1.2 7.7 21.1 33.2 12.4 4.4 15.3 3.2 13.9 5.6 6.9 11.2 6.8 8.8 20.5 15.0 6.2 4.2 5.5 3.2 22.7 17.2 13.5 8.2 11.7 13.4 2.4 23.6 14.6 1.7 5.5 8.7 14.8 18.3 7.7 6.3 5.6 13.9 5.1 9.4 7.6 19.5 1.0 6.3 4.6 1.5 14.7 9.1 19.8 20.2 8.1 6.5 5.0 10.2 4.0 5.6 6.2 8.0 5.7 4.9 11.8 4.3 5.0 6.1 6.9 10.3 10.2 4.0 7.8 2.4 9.6 4.1 1.3 7.2 3.5 6.4 1.0 9.2 3.8 8.6 5.8 2.1 8.3 1.2 6.4 2.3 7.2 2.5 11.5 4.2 3.0 3.9 10.2 8.4 13.6 4.7 5.2 3.2 6.3 7.9 4.4 3.2 8.8 21.6 2.8 10.3 5.3 3.4 5.0 7.6 21.7 5.4 6.9 4.2 2.7 10.6 3.1 4.1 0.5 1.0 0.2 1.0 0.8 0.8 1.2 0.8 1.2 1.4 1.5 0.9 0.7 0.0 0.5 3.4 0.4 1.0 0.6 19.1 18.7 21.1 33.2 20.5 15.0 22.7 17.2 23.6 13.9 19.5 19.8 5.0 6.4 2.0 2.0 0.7 1.7 3.8 0.9 4.0 13.3 3.0 4.4 8.1 4.3 0.6 0.0 10.4 2.5 0.4 0.6 1.9 3.2 5.0 0.4 2.6 2.7 26.5 0.0 7.1 2.5 2.1 4.2 2.0 1.1 0.0 2.9 3.3 2.8 3.3 21.9 7.7 1.4 2.0 1.9 1.4 10.4 7.5 2.9 0.0 1.9 2.8 7.5 0.0 2.0 2.5 1.8 1.4 9.8 1.0 2.5 0.9 2.9 0.2 9.7 6.6 3.1 4.9 3.0 3.5 1.8 0.3 0.3 1.3 1.5 0.8 1.5 PEMT "PEMPT, PEMT2" ENSG00000133027 "Phosphatidylethanolamine N-methyltransferase" Q9UBM1 17 17505563-17591708 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 166.2;liver: 267.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 122.9;Hepatocytes: 220.1;Peritubular cells: 346.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042375, HPA073930" Approved Supported "Endoplasmic reticulum,Vesicles,Mitochondria,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" "Endoplasmic reticulum, Mitochondria" "Vesicles, Cytosol" "HPA042375: AB_10796905, HPA073930: " "unprognostic (1.39e-2)" "unprognostic (3.43e-1)" "unprognostic (2.43e-2)" "prognostic favorable (6.77e-6)" "unprognostic (2.85e-1)" "unprognostic (7.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.28e-1)" "unprognostic (3.89e-1)" "unprognostic (3.41e-2)" "unprognostic (5.47e-3)" "unprognostic (2.67e-1)" "unprognostic (8.63e-3)" "unprognostic (2.08e-1)" "unprognostic (2.10e-1)" "unprognostic (6.66e-2)" "unprognostic (7.60e-2)" 71.6 33.9 13.2 5.2 13.6 9.2 92.7 16.3 20.0 47.4 12.7 13.6 15.0 36.9 166.2 26.8 26.5 5.4 24.5 13.0 15.2 30.2 267.4 25.8 5.2 14.9 15.3 27.9 32.2 13.3 24.7 7.3 16.8 30.8 3.4 2.8 27.1 24.0 29.5 34.3 13.7 6.8 15.1 12.8 19.5 40.8 14.2 5.6 33.5 10.7 4.5 21.1 24.2 17.2 34.3 64.7 16.5 43.4 34.6 23.8 25.1 21.6 19.0 28.5 22.4 38.2 22.6 29.8 38.1 21.9 21.6 39.9 24.6 12.8 7.2 22.2 86.9 14.8 33.2 55.4 38.4 13.5 21.4 24.9 26.7 19.2 29.1 9.7 15.7 41.3 14.6 12.3 12.9 66.0 23.9 24.2 23.2 65.5 52.4 22.2 26.7 27.5 24.1 12.5 16.7 39.5 15.3 10.1 39.2 31.5 15.6 5.1 13.9 28.1 28.2 47.4 18.9 17.0 12.1 5.5 25.9 18.5 23.6 1.9 41.1 2.1 16.9 39.0 24.8 23.5 22.2 21.5 30.5 28.3 17.2 19.4 3.1 29.3 28.0 27.7 22.4 21.3 13.2 13.6 16.3 20.0 13.0 15.2 14.9 15.3 16.8 15.1 14.2 17.2 38.1 16.0 17.5 4.9 12.4 18.2 21.0 27.9 39.3 4.5 33.0 45.1 15.5 11.5 24.9 27.6 0.0 19.5 5.9 9.3 17.6 33.3 2.9 21.8 122.9 18.5 68.8 17.1 5.4 38.5 21.6 30.4 8.2 23.8 12.7 52.4 10.4 220.1 23.5 5.0 6.8 30.9 24.4 13.7 12.2 14.9 94.8 11.2 21.4 3.7 5.7 34.7 2.1 9.5 4.0 25.7 10.8 346.8 15.3 35.1 21.7 32.3 14.2 6.1 6.6 20.0 23.6 21.0 24.9 39.5 18.2 14.6 12.5 49.3 24.1 23.8 PEX11B ENSG00000131779 "Peroxisomal biogenesis factor 11 beta" O96011 1 145911350-145918717 "Disease related genes, Predicted membrane proteins" "Peroxisome biogenesis" "Peroxisome biogenesis disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017150, HPA050104" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 43: THP-1 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles Nucleoplasm "HPA017150: , HPA050104: AB_2681017" "unprognostic (4.59e-2)" "unprognostic (3.13e-2)" "unprognostic (1.80e-1)" "unprognostic (2.29e-1)" "unprognostic (3.62e-1)" "unprognostic (1.18e-1)" "prognostic unfavorable (2.67e-4)" "prognostic favorable (6.85e-4)" "unprognostic (1.19e-1)" "unprognostic (4.08e-2)" "unprognostic (2.10e-1)" "unprognostic (8.48e-2)" "unprognostic (6.96e-2)" "unprognostic (1.85e-1)" "unprognostic (1.84e-1)" "unprognostic (7.62e-3)" "unprognostic (4.28e-1)" 17.5 25.1 34.7 19.0 35.8 13.3 31.2 32.5 42.5 24.6 33.3 24.9 24.6 23.4 33.1 34.3 25.7 17.0 28.0 36.3 38.1 32.4 27.1 20.1 27.4 33.3 33.0 24.6 27.2 33.5 24.5 23.1 35.1 24.3 27.6 20.2 28.7 25.6 39.8 28.1 25.9 21.0 31.6 27.7 28.3 30.8 34.1 30.2 26.4 34.9 34.7 23.2 22.2 34.2 27.1 24.4 21.0 21.1 48.6 37.9 21.9 26.8 35.3 34.4 26.5 11.3 30.7 25.2 28.1 38.3 16.6 31.9 18.6 40.0 24.0 28.4 14.1 15.6 14.8 29.2 68.3 46.9 27.5 49.9 49.3 23.3 22.8 43.9 44.5 34.8 28.7 40.5 54.7 43.1 35.8 43.5 7.5 57.4 29.5 33.0 31.5 55.5 58.8 19.1 14.7 24.0 20.2 38.4 24.7 20.5 53.2 72.0 39.7 23.1 18.2 30.3 19.8 43.1 54.0 35.1 38.5 26.3 16.0 89.6 64.7 47.3 58.5 60.9 64.8 93.2 67.5 65.4 70.8 84.1 74.7 67.9 32.4 71.1 60.5 94.9 79.6 82.7 34.7 35.8 32.5 42.5 36.3 38.1 33.3 33.0 35.1 31.6 34.1 34.2 5.0 16.0 10.3 9.8 17.0 19.4 9.2 41.3 26.7 8.0 16.8 17.0 12.8 17.2 20.7 40.5 0.0 37.9 19.6 20.2 45.0 13.7 12.2 8.2 7.0 12.3 12.7 14.1 13.0 13.8 13.9 11.1 19.4 7.4 3.8 9.3 18.2 32.9 23.0 5.0 13.5 16.0 20.3 18.3 10.7 21.1 14.0 12.9 21.4 4.7 27.1 12.6 25.7 9.5 12.9 16.0 11.4 19.9 17.4 10.1 20.1 34.5 22.9 5.1 6.6 5.8 10.3 41.1 24.3 34.0 22.0 20.0 13.8 11.6 15.8 9.4 PEX2 "PAF-1, PMP35, PXMP3, RNF72, ZWS3" ENSG00000164751 "Peroxisomal biogenesis factor 2" P28328 8 76980258-77001044 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Peroxisome biogenesis" "Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 133.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010983, HPA011410, HPA027729" Approved Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA010983: , HPA011410: AB_1854922, HPA027729: AB_10610416" "unprognostic (6.42e-2)" "unprognostic (2.90e-2)" "unprognostic (4.64e-2)" "unprognostic (2.35e-1)" "unprognostic (9.91e-2)" "unprognostic (2.33e-1)" "unprognostic (6.19e-2)" "unprognostic (2.22e-1)" "unprognostic (3.16e-2)" "unprognostic (1.37e-1)" "unprognostic (2.85e-2)" "unprognostic (2.07e-2)" "unprognostic (9.57e-3)" "unprognostic (2.48e-1)" "unprognostic (9.49e-2)" "unprognostic (3.06e-2)" "unprognostic (1.09e-3)" 39.8 45.9 33.1 33.5 36.6 35.8 53.9 34.2 45.6 40.7 38.6 43.1 39.8 33.3 42.4 32.9 41.8 31.9 39.7 32.1 35.1 53.6 43.7 36.5 39.4 37.3 34.5 33.3 39.0 57.7 27.2 24.7 37.6 44.2 39.6 66.5 50.9 83.4 61.8 24.5 41.0 35.3 37.3 36.5 48.3 22.1 34.5 48.8 53.2 44.6 35.7 35.7 31.3 43.3 88.2 29.3 46.9 47.9 50.7 63.2 24.5 64.4 75.3 49.9 55.2 18.4 76.9 50.2 93.6 59.9 39.7 33.3 33.1 50.1 61.2 93.3 28.5 61.1 26.0 28.3 33.9 51.5 46.5 70.9 43.5 37.8 45.6 77.0 55.3 79.3 34.4 46.7 53.9 26.4 90.4 30.1 27.2 126.4 26.3 16.5 37.4 42.1 59.9 61.6 16.7 43.0 41.9 192.0 36.9 39.8 58.7 36.1 54.7 44.4 58.1 57.7 32.4 86.0 53.8 87.9 56.5 26.7 50.2 179.9 55.6 102.6 57.2 58.0 51.2 46.1 39.6 46.5 46.3 50.5 51.6 49.3 38.6 83.1 67.8 46.8 48.6 71.7 33.1 36.6 34.2 45.6 32.1 35.1 37.3 34.5 37.6 37.3 34.5 43.3 28.0 48.1 25.2 32.3 29.7 18.1 31.0 57.8 28.5 28.9 38.9 33.1 27.2 28.6 38.4 27.6 12.5 42.8 38.3 30.2 133.1 52.3 5.6 36.5 19.9 20.7 28.9 25.6 11.9 49.1 24.8 29.8 20.4 22.2 18.3 20.2 25.7 36.7 26.6 13.5 15.2 37.5 48.8 39.1 22.4 7.3 29.5 26.8 28.4 16.9 36.3 68.4 53.5 31.7 45.9 42.0 28.2 35.7 41.7 36.3 43.3 61.4 36.6 34.4 6.6 34.9 24.6 13.7 20.8 28.6 21.0 34.8 37.6 27.7 30.0 43.0 PEX6 "PAF-2, PXAAA1" ENSG00000124587 "Peroxisomal biogenesis factor 6" Q13608 6 42963865-42979181 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Peroxisome biogenesis" "Amelogenesis imperfecta, Deafness, Disease variant, Peroxisome biogenesis disorder, Zellweger syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 76.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 78.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025924, HPA074179" Supported Supported "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Vesicles" "Nuclear bodies" "HPA025924: AB_1855230, HPA074179: " "unprognostic (7.32e-3)" "unprognostic (2.43e-1)" "unprognostic (1.38e-1)" "unprognostic (9.16e-2)" "unprognostic (9.18e-2)" "unprognostic (3.27e-1)" "unprognostic (8.88e-2)" "unprognostic (5.92e-2)" "unprognostic (3.36e-1)" "unprognostic (7.12e-2)" "unprognostic (7.24e-3)" "unprognostic (5.31e-2)" "unprognostic (3.79e-3)" "unprognostic (1.86e-1)" "unprognostic (1.13e-1)" "unprognostic (1.81e-1)" "unprognostic (1.55e-1)" 11.6 20.5 24.9 9.2 25.2 9.5 12.1 23.9 27.7 19.1 25.5 16.3 9.3 15.5 7.7 16.4 22.7 9.6 18.7 25.1 25.5 16.5 27.7 10.0 14.5 27.2 25.5 26.1 76.2 15.2 24.3 9.6 24.2 21.6 7.8 9.9 14.8 11.4 23.4 14.0 16.3 9.6 23.9 17.5 16.3 16.2 25.1 14.7 19.8 15.0 10.4 17.3 15.7 25.2 35.0 16.4 8.1 30.6 29.6 28.3 8.4 6.0 9.4 4.8 10.0 10.5 10.1 14.1 8.2 14.3 20.5 32.2 28.7 31.1 5.0 27.6 15.2 4.7 24.4 6.2 20.0 4.8 9.4 35.5 35.5 19.9 5.5 39.1 24.7 18.9 25.2 14.1 10.7 3.9 12.7 15.8 10.0 78.8 14.3 26.8 14.3 5.8 12.3 10.0 25.4 11.1 5.6 21.9 32.7 13.1 43.2 21.2 14.0 15.2 2.9 7.5 14.0 21.0 19.8 19.7 5.2 24.6 12.4 1.3 1.3 2.1 1.2 1.1 2.1 1.0 1.8 2.5 1.9 1.9 2.2 2.1 0.8 2.0 0.7 1.0 0.9 1.1 24.9 25.2 23.9 27.7 25.1 25.5 27.2 25.5 24.2 23.9 25.1 25.2 5.6 6.4 2.6 19.9 5.6 5.0 10.2 6.2 10.8 15.2 11.8 12.7 4.1 10.0 5.6 7.3 2.1 11.4 5.4 10.2 13.7 2.8 2.5 17.6 10.6 5.8 5.4 1.7 24.6 1.5 6.7 9.2 11.2 9.1 0.0 19.8 8.6 14.1 5.8 21.9 22.4 8.5 6.1 9.7 3.2 3.6 14.6 5.4 8.8 9.4 4.5 11.8 9.2 13.0 16.6 1.9 10.4 9.4 3.1 6.3 15.1 13.9 14.3 7.0 0.0 13.0 6.6 7.3 2.6 6.3 5.5 7.4 7.8 26.1 10.5 6.6 PEX7 "PTS2R, RD" ENSG00000112357 "Peroxisomal biogenesis factor 7" O00628 6 136822564-136913934 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cataract, Deafness, Disease variant, Ichthyosis, Peroxisome biogenesis disorder, Retinitis pigmentosa, Rhizomelic chondrodysplasia punctata" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049202 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Vesicles" "HPA049202: AB_2680674" "unprognostic (1.36e-2)" "unprognostic (2.07e-2)" "prognostic favorable (1.61e-4)" "unprognostic (4.01e-3)" "unprognostic (2.50e-2)" "unprognostic (6.38e-2)" "unprognostic (1.46e-1)" "unprognostic (1.71e-2)" "unprognostic (4.87e-2)" "unprognostic (1.23e-1)" "unprognostic (2.49e-1)" "unprognostic (6.88e-2)" "prognostic favorable (1.85e-10)" "unprognostic (3.57e-1)" "unprognostic (1.44e-1)" "unprognostic (2.52e-2)" "unprognostic (2.65e-1)" 5.2 14.8 4.6 2.0 4.8 3.8 11.9 6.0 5.2 6.8 5.1 7.9 5.3 4.2 17.2 7.3 8.7 4.5 11.7 4.2 4.2 15.6 9.1 4.9 3.2 4.3 4.4 5.0 26.9 17.1 6.0 4.1 4.5 10.4 8.4 6.9 10.6 6.4 10.7 11.2 4.7 3.3 4.4 3.3 15.6 10.0 4.7 3.7 11.0 9.8 3.3 5.4 6.7 5.5 4.4 4.3 4.4 6.2 6.6 9.8 2.4 6.1 8.9 7.5 7.4 4.9 6.0 1.5 11.3 8.3 8.5 5.3 3.3 13.8 9.8 5.7 7.5 6.4 4.3 0.9 13.9 8.1 5.3 9.6 13.1 5.4 7.9 8.7 5.4 12.0 13.0 5.2 10.6 13.4 3.5 7.9 5.0 13.9 8.3 4.8 3.4 5.7 17.4 6.4 8.3 10.6 6.5 9.0 8.4 4.9 5.8 7.7 2.5 4.8 1.7 7.3 5.3 6.9 5.1 0.0 4.2 6.4 4.9 2.9 1.3 2.2 0.7 1.0 0.7 1.5 1.3 1.6 2.3 1.0 2.4 1.5 0.9 1.6 1.9 1.8 2.3 0.9 4.6 4.8 6.0 5.2 4.2 4.2 4.3 4.4 4.5 4.4 4.7 5.5 4.9 3.2 9.4 10.7 6.3 12.1 14.9 16.5 9.1 9.1 19.5 13.8 18.7 11.5 14.7 11.0 8.4 19.6 2.3 11.6 60.7 16.5 12.5 18.7 6.4 5.6 10.3 15.8 12.4 22.7 21.0 6.8 10.2 11.1 14.0 7.9 6.1 7.0 12.4 0.0 14.7 21.8 30.5 5.7 6.2 10.2 9.0 6.4 14.2 5.6 11.9 20.8 4.1 17.6 19.9 16.7 13.2 9.8 3.7 16.0 15.0 38.3 16.1 9.9 6.6 5.7 8.2 30.6 16.7 15.4 18.2 17.1 6.6 24.3 17.2 17.4 PFAS "FGARAT, GATD8, KIAA0361, PURL" ENSG00000178921 "Phosphoribosylformylglycinamidine synthase" O15067 17 8247618-8270491 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 49.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022140, HPA022886" Enhanced Approved Vesicles NA NA 670000 "Cluster 1: Neutrophils - Mixed function" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Vesicles "HPA022140: AB_1855232, HPA022886: AB_1855233" "unprognostic (1.90e-1)" "unprognostic (9.21e-2)" "unprognostic (2.12e-1)" "unprognostic (5.19e-3)" "unprognostic (2.59e-1)" "unprognostic (6.40e-2)" "prognostic unfavorable (9.19e-4)" "unprognostic (3.19e-1)" "unprognostic (1.42e-2)" "unprognostic (1.91e-1)" "unprognostic (5.47e-3)" "unprognostic (1.08e-3)" "unprognostic (9.51e-3)" "unprognostic (3.63e-2)" "unprognostic (6.57e-2)" "unprognostic (2.88e-3)" "unprognostic (3.85e-1)" 8.4 9.9 4.7 7.8 5.1 9.8 8.2 6.2 5.8 7.8 2.8 6.7 4.8 9.0 2.6 8.4 8.0 2.8 6.3 5.1 3.3 11.0 10.1 5.8 9.8 3.9 3.9 9.7 10.3 5.6 5.5 5.2 4.6 6.9 5.6 5.8 6.4 4.7 6.4 6.8 7.7 6.8 3.3 11.0 7.8 7.8 3.9 7.5 7.8 3.2 8.2 7.6 6.2 6.0 15.6 67.0 33.8 50.2 12.1 10.0 38.7 19.4 7.4 35.1 26.4 32.9 13.7 69.8 30.8 11.4 12.4 35.1 78.5 25.6 25.8 30.6 64.0 40.0 63.2 41.9 10.4 32.9 28.3 9.5 6.2 40.5 25.5 9.9 29.5 36.6 54.8 10.1 13.7 23.0 58.1 28.4 55.7 8.5 29.9 86.0 35.2 32.6 16.1 25.5 20.4 31.7 24.1 15.3 22.2 17.9 15.3 14.9 20.9 19.2 25.0 35.7 49.0 11.8 23.5 33.7 21.0 45.4 32.9 20.2 5.1 12.7 6.8 4.5 8.7 14.8 8.8 7.9 4.4 16.7 10.9 8.6 49.1 5.2 3.7 12.9 5.0 2.3 4.7 5.1 6.2 5.8 5.1 3.3 3.9 3.9 4.6 3.3 3.9 6.0 2.9 0.0 7.9 3.9 6.0 2.4 1.7 1.9 1.8 8.1 4.5 3.7 4.3 1.5 4.1 3.7 6.2 5.2 3.2 2.1 0.0 3.7 2.1 2.4 5.9 3.6 0.0 9.2 5.8 3.0 4.3 4.0 5.6 3.7 1.3 9.7 2.5 4.2 4.6 1.7 5.4 3.5 2.0 2.5 1.4 1.1 5.3 3.4 3.6 4.7 4.5 1.6 4.1 6.6 3.9 1.9 4.9 1.5 5.3 2.9 0.8 2.7 5.1 7.3 0.0 5.1 3.2 5.6 8.8 3.9 2.0 3.1 3.3 7.7 6.2 1.4 PFN3 ENSG00000196570 "Profilin 3" P60673 5 177400109-177400661 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 27 "testis: 25.7" "Group enriched" "Detected in some" 176 "Early spermatids: 666.2;Late spermatids: 1589.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA038274 Approved Vesicles,Cytosol NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Cytosol" "HPA038274: " "unprognostic (1.03e-2)" "unprognostic (1.13e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 666.2 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1589.2 6.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 5.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PGBD2 ENSG00000185220 "PiggyBac transposable element derived 2" Q6P3X8 1 248906196-248919946 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 27.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "HPA029888, HPA029889, HPA029890" Uncertain Approved Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA029888: AB_10600088, HPA029889: AB_10611386, HPA029890: AB_10602002" "unprognostic (1.06e-2)" "unprognostic (8.05e-2)" "unprognostic (2.56e-2)" "unprognostic (3.03e-2)" "unprognostic (1.40e-1)" "prognostic favorable (6.08e-4)" "unprognostic (1.94e-2)" "unprognostic (2.11e-2)" "unprognostic (2.71e-3)" "unprognostic (1.84e-1)" "unprognostic (2.59e-1)" "unprognostic (1.18e-2)" "prognostic unfavorable (7.86e-4)" "unprognostic (2.41e-1)" "unprognostic (7.91e-2)" "unprognostic (1.25e-1)" "prognostic favorable (2.05e-4)" 3.2 3.6 3.5 5.4 3.7 4.3 5.8 5.4 3.9 4.9 2.8 4.6 5.9 4.8 5.1 6.0 3.8 4.7 2.8 2.9 4.3 3.7 7.2 3.6 7.5 3.5 3.0 5.6 6.7 3.3 2.7 5.8 3.6 5.1 6.1 4.4 5.4 3.3 1.4 8.1 7.1 3.6 2.1 9.4 5.2 6.0 4.1 5.6 6.5 2.4 7.1 4.4 4.7 6.3 4.4 5.7 8.5 5.2 7.7 5.0 10.7 4.1 3.4 6.9 6.3 4.2 5.6 11.2 5.0 3.9 3.8 6.9 4.7 5.2 7.6 6.7 2.1 10.7 10.0 6.4 4.4 5.9 10.3 4.5 5.5 8.2 4.5 5.5 3.9 3.8 17.5 9.5 5.0 7.3 2.0 6.5 8.4 14.6 6.6 13.1 2.8 3.5 4.0 5.5 3.0 5.6 6.0 8.5 7.0 5.9 3.6 11.2 5.0 4.7 4.5 4.3 4.6 8.8 9.2 4.1 5.0 12.7 4.4 11.0 6.0 9.4 6.1 4.4 6.1 8.3 5.5 5.9 5.5 8.4 5.5 6.8 4.6 5.9 6.8 2.7 4.1 4.1 3.5 3.7 5.4 3.9 2.9 4.3 3.5 3.0 3.6 2.1 4.1 6.3 5.3 0.0 8.9 2.6 11.2 5.2 2.9 7.6 14.8 3.6 7.3 5.6 2.2 2.8 9.1 5.5 2.1 11.5 7.9 6.9 1.9 5.1 3.5 6.0 4.9 5.9 1.2 17.9 2.3 3.0 4.4 3.5 6.1 6.9 2.5 7.8 3.3 3.4 2.9 1.7 2.7 4.3 6.1 3.3 4.4 2.7 3.1 3.7 7.2 2.8 4.6 3.2 6.2 6.0 4.3 2.2 6.0 1.9 5.7 2.8 9.0 3.0 4.6 2.7 0.0 4.0 5.6 14.5 10.2 7.9 6.5 27.8 7.8 4.8 5.1 2.1 PGLYRP1 "PGLYRP, PGRP, PGRP-S, PGRPS, TAG7, TNFSF3L" ENSG00000008438 "Peptidoglycan recognition protein 1" O75594 19 46019153-46023053 "Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "bone marrow: 629.4" "Cell type enhanced" "Detected in some" "Erythroid cells: 3.2;Excitatory neurons: 1.7;Inhibitory neurons: 1.5" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 3.4" "Group enriched" "Detected in some" 202 "eosinophil: 443.7;neutrophil: 494.6" "Lineage enriched" "Detected in many" 213 "granulocytes: 494.6" "Cell line enhanced" "Detected in some" "A549: 3.1;HEK 293: 1.8;HeLa: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045702, HPA070227" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" NA NA 35000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "Nucleoplasm, Cytosol" "HPA045702: AB_10960204, HPA070227: " "unprognostic (2.87e-2)" "unprognostic (4.26e-1)" "unprognostic (1.32e-1)" "unprognostic (3.04e-1)" "unprognostic (1.58e-1)" "unprognostic (4.93e-3)" "unprognostic (2.20e-1)" "unprognostic (6.46e-2)" "unprognostic (7.77e-2)" "unprognostic (2.61e-2)" "unprognostic (8.51e-3)" "unprognostic (7.18e-2)" "unprognostic (2.04e-2)" "unprognostic (2.96e-1)" "unprognostic (1.03e-1)" "unprognostic (1.73e-1)" "unprognostic (4.37e-3)" 1.5 0.3 0.3 1.8 1.1 629.4 0.3 3.4 1.5 0.1 0.0 0.3 0.6 0.2 0.0 0.5 0.6 0.2 1.7 0.6 0.0 0.8 2.5 8.7 0.5 0.0 0.1 0.1 0.5 0.0 0.7 0.9 0.0 0.2 0.0 0.0 0.5 0.0 0.3 1.0 0.7 0.1 0.0 42.5 0.4 1.0 0.0 3.3 0.5 2.3 0.0 0.4 0.2 0.0 0.3 3.1 0.5 0.3 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.5 0.2 0.8 0.1 0.0 0.2 1.2 0.0 0.0 0.0 0.8 1.8 0.3 1.7 0.1 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.3 0.3 0.0 0.2 0.2 0.9 0.2 0.0 1.2 0.7 0.1 0.0 0.0 1.2 0.3 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.3 0.4 0.7 0.6 0.3 0.4 0.7 0.0 0.2 0.4 443.7 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 494.6 0.0 2.3 0.0 0.1 3.9 0.3 1.1 3.4 1.5 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 3.2 1.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.5 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 PGLYRP4 "PGLYRPIbeta, PGRP-Ibeta, PGRPIB, SBBI67" ENSG00000163218 "Peptidoglycan recognition protein 4" Q96LB8 1 153330120-153348841 "Metabolic proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 8.5;esophagus: 8.2;skin 1: 15.1;vagina: 10.3" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 30.1;Club cells: 9.7" "Cancer enhanced" "Detected in some" "head and neck cancer: 7.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 3.7;HDLM-2: 2.2;Karpas-707: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" CAB025879 Approved "Vesicles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" "CAB025879: " "unprognostic (2.76e-2)" "unprognostic (1.19e-1)" "unprognostic (6.10e-2)" "unprognostic (1.34e-2)" "unprognostic (3.61e-3)" "unprognostic (1.46e-1)" "unprognostic (3.13e-1)" "unprognostic (5.42e-2)" "unprognostic (3.99e-2)" "unprognostic (1.07e-2)" "unprognostic (2.15e-1)" "unprognostic (1.81e-1)" "unprognostic (1.88e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 15.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 2.3 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 30.1 0.6 0.0 0.0 0.1 0.3 0.0 9.7 0.0 0.0 0.0 0.0 0.1 0.0 1.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 2.0 0.0 0.3 0.3 0.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.4 0.0 2.4 0.0 0.0 0.0 0.3 0.0 0.0 4.0 3.4 0.3 0.0 0.0 0.2 0.2 PHF14 KIAA0783 ENSG00000106443 "PHD finger protein 14" O94880 7 10973336-11169623 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000538, HPA017376" Supported Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 15: NK-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "Nucleoplasm, Cytosol" "HPA000538: AB_1079604, HPA017376: AB_2732420" "unprognostic (1.16e-1)" "unprognostic (3.17e-1)" "unprognostic (3.73e-3)" "unprognostic (7.38e-3)" "unprognostic (8.05e-2)" "unprognostic (3.38e-1)" "unprognostic (4.66e-3)" "unprognostic (1.80e-1)" "unprognostic (5.32e-3)" "unprognostic (6.76e-2)" "unprognostic (2.94e-2)" "unprognostic (3.10e-1)" "unprognostic (4.84e-3)" "unprognostic (1.24e-1)" "unprognostic (2.30e-2)" "unprognostic (1.87e-2)" "unprognostic (2.33e-1)" 9.9 8.0 17.2 8.6 15.6 5.5 13.7 17.5 26.9 9.1 12.7 9.8 8.2 13.1 7.8 8.4 8.8 9.3 5.3 17.0 16.1 10.0 11.4 8.6 9.9 16.5 16.7 14.5 7.1 9.5 7.9 8.4 17.3 10.0 10.4 6.7 7.9 8.1 6.0 8.5 8.2 11.0 14.2 10.3 10.3 9.3 16.0 17.8 9.2 7.8 10.2 9.2 7.6 16.9 16.4 32.8 46.4 49.2 16.2 15.6 23.1 12.6 10.0 14.5 15.9 29.5 28.9 62.4 22.7 11.7 32.7 22.8 42.4 14.6 16.0 23.1 17.3 31.1 28.1 38.0 14.8 70.2 28.8 14.2 15.0 17.3 30.9 20.4 21.2 24.2 42.4 21.6 17.6 21.6 28.0 30.4 39.3 68.1 24.4 45.9 30.3 19.8 15.0 30.6 42.2 58.3 19.5 64.6 21.1 33.6 34.6 50.1 20.6 20.3 27.1 13.6 25.0 27.7 51.1 43.2 14.4 57.8 48.6 1.0 0.9 0.6 1.3 0.8 1.0 1.8 1.4 1.6 0.5 1.4 1.9 1.7 0.0 1.4 0.8 2.7 1.9 0.4 17.2 15.6 17.5 26.9 17.0 16.1 16.5 16.7 17.3 14.2 16.0 16.9 80.6 41.7 41.6 141.0 66.9 57.5 68.6 27.5 68.9 92.7 80.3 91.3 22.7 37.1 44.2 33.1 58.4 68.8 58.4 54.6 27.4 92.0 23.9 40.9 82.7 77.4 92.2 46.9 223.8 84.3 80.9 65.9 55.5 48.1 56.5 103.7 64.2 43.6 42.1 79.1 260.6 72.3 42.7 39.6 24.7 16.2 102.9 39.1 37.4 116.2 58.0 36.5 87.6 263.4 200.8 90.4 45.9 116.9 34.3 82.0 46.0 35.9 28.0 63.3 52.6 71.0 67.6 142.3 133.7 56.5 52.4 39.8 58.6 73.7 72.0 54.2 PHGR1 ENSG00000233041 "Proline, histidine and glycine rich 1" C9JFL3 15 40351033-40356434 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "intestine: 2541.0" "Cell type enhanced" "Detected in some" "Distal enterocytes: 19911.4;Intestinal goblet cells: 8220.0;Paneth cells: 9497.7;Proximal enterocytes: 51149.4" "Group enriched" "Detected in many" 16 "colorectal cancer: 248.3;stomach cancer: 94.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 14 "OE19: 833.5" HPA068787 Enhanced Approved Vesicles NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA068787: AB_2686035" "prognostic favorable (2.05e-4)" "unprognostic (1.73e-1)" "unprognostic (5.18e-2)" "unprognostic (1.18e-1)" "unprognostic (2.80e-1)" "unprognostic (1.20e-1)" "unprognostic (1.27e-2)" 3.7 0.4 0.1 88.8 0.2 0.2 11.1 0.3 0.1 0.8 0.0 2541.0 881.0 1.2 0.0 2.0 3.5 0.3 0.3 0.1 0.1 1.9 1.0 0.2 1.2 0.1 0.1 0.5 1.9 0.0 0.5 0.0 0.1 2.5 370.7 0.0 0.3 3.0 0.4 3.7 2320.2 17.3 0.1 0.4 177.1 0.3 0.1 0.0 0.4 0.0 0.0 5.6 1.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 18.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.0 0.1 833.5 0.3 0.1 0.0 10.8 0.0 1.5 61.5 7.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.3 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.0 46.0 0.0 0.2 0.3 0.0 0.0 40.2 38.0 0.0 117.2 0.0 0.0 0.0 0.0 0.1 19911.4 0.0 2.5 0.1 0.0 0.0 0.2 1938.2 0.0 0.0 0.2 0.0 0.5 884.8 0.1 213.9 0.0 0.0 0.6 0.0 0.0 0.0 8220.0 20.3 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 9497.7 0.0 2.1 1.1 51149.4 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 32.6 0.0 4881.6 1.0 PHKA1 PHKA ENSG00000067177 "Phosphorylase kinase regulatory subunit alpha 1" P46020 X 72578814-72714319 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Muscle protein" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "parathyroid gland: 32.0;skeletal muscle: 102.6;tongue: 89.2" "Cell type enriched" "Detected in many" 4 "Astrocytes: 85.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 39.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001081, HPA075355" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Vesicles, Cytosol" "HPA001081: AB_1079607, HPA075355: " "unprognostic (3.68e-3)" "unprognostic (9.19e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (6.84e-4)" "unprognostic (3.52e-1)" "unprognostic (5.48e-2)" "unprognostic (1.23e-2)" "unprognostic (9.64e-2)" "unprognostic (1.85e-1)" "unprognostic (1.97e-1)" "unprognostic (2.18e-1)" "unprognostic (4.76e-1)" "unprognostic (9.45e-3)" "unprognostic (9.94e-2)" "unprognostic (2.02e-1)" "unprognostic (2.08e-1)" "unprognostic (1.12e-1)" 3.2 17.7 6.9 1.0 11.4 0.7 4.8 8.9 5.7 2.6 17.0 4.0 1.1 3.3 6.5 5.6 3.8 3.2 7.5 6.0 8.7 2.7 2.3 2.1 1.1 8.8 11.9 8.3 7.6 32.0 9.8 1.8 9.1 6.0 3.3 3.9 7.1 6.4 102.6 3.4 2.1 3.4 7.9 3.4 6.9 2.1 10.4 4.0 6.9 89.2 1.4 4.8 3.5 6.7 15.3 21.2 1.2 12.4 7.2 6.8 12.9 2.8 2.6 0.5 0.1 6.2 13.3 0.0 8.2 0.3 15.1 5.9 24.9 10.3 0.8 39.2 25.1 7.0 17.4 5.7 7.5 0.0 0.0 9.1 10.0 2.4 16.7 12.5 14.5 12.7 11.0 0.0 13.6 11.0 11.1 0.7 16.5 25.2 28.0 0.0 0.0 0.0 3.7 7.2 12.9 15.3 13.4 17.3 0.2 15.4 6.2 0.6 7.5 0.0 6.2 2.7 7.3 17.1 17.1 0.0 5.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 11.4 8.9 5.7 6.0 8.7 8.8 11.9 9.1 7.9 10.4 6.7 5.8 0.0 3.7 85.2 0.5 2.4 6.5 2.3 4.0 2.4 5.2 3.7 6.6 1.5 3.5 11.0 8.4 1.0 0.1 0.8 0.0 1.6 0.4 4.8 1.4 3.5 2.4 4.0 5.3 2.7 1.1 2.5 3.6 2.9 6.3 3.4 5.7 1.9 1.6 3.3 16.0 1.8 4.1 10.4 0.7 0.1 3.1 0.6 1.8 6.5 0.0 1.5 0.0 18.6 0.5 5.4 0.4 8.6 1.3 9.0 0.4 1.6 6.6 3.3 0.0 7.1 1.9 0.4 1.0 5.6 3.4 0.5 0.3 1.9 2.6 8.9 PHLDB1 "FLJ00141, KIAA0638, LL5a" ENSG00000019144 "Pleckstrin homology like domain family B member 1" Q86UU1 11 118606440-118658031 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 133.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 87.2;Late spermatids: 87.7;Oligodendrocytes: 244.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 105.2;ASC TERT1: 105.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037959, HPA038448" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA No "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Vesicles, Cytosol" "Plasma membrane" "HPA037959: AB_10673651, HPA038448: AB_10697390" "unprognostic (7.81e-2)" "unprognostic (8.32e-3)" "unprognostic (1.13e-1)" "unprognostic (9.36e-3)" "unprognostic (8.28e-2)" "unprognostic (1.55e-1)" "unprognostic (4.37e-3)" "unprognostic (1.22e-1)" "unprognostic (3.21e-2)" "unprognostic (1.10e-1)" "unprognostic (1.44e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (6.36e-6)" "unprognostic (7.09e-2)" "unprognostic (2.42e-2)" "unprognostic (3.69e-2)" "unprognostic (1.44e-1)" 52.6 8.1 39.2 11.5 79.7 0.5 38.9 42.5 66.0 39.1 3.8 23.8 9.2 38.4 2.6 9.1 30.2 21.6 33.0 42.3 49.2 15.8 3.2 26.8 4.6 64.3 64.6 31.9 22.2 4.5 8.8 24.6 56.0 16.7 6.4 1.6 11.1 15.8 13.3 15.1 15.3 18.6 33.4 12.5 14.3 12.0 75.3 3.1 20.3 13.6 2.3 21.9 22.9 133.7 4.8 7.5 28.9 14.2 105.2 105.9 10.1 21.9 26.6 12.7 7.4 11.2 31.8 0.0 40.2 44.3 17.2 18.6 6.6 44.8 2.0 0.7 4.2 8.6 5.7 5.5 27.2 0.0 15.8 55.8 9.6 17.8 12.5 28.3 36.6 0.7 7.5 0.3 16.7 3.4 0.1 0.5 10.2 0.4 3.8 1.1 7.5 0.7 12.5 6.8 6.5 14.5 55.8 4.7 15.6 11.3 20.1 2.7 45.4 25.9 22.9 13.2 18.3 0.2 0.0 0.1 7.5 1.5 29.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 39.2 79.7 42.5 66.0 42.3 49.2 64.3 64.6 56.0 33.4 75.3 133.7 34.4 6.4 13.7 53.2 1.6 18.4 9.2 13.7 14.2 4.0 7.2 19.6 5.6 1.5 6.3 31.3 0.0 1.0 2.5 34.2 0.0 9.4 78.3 11.6 87.2 32.1 8.4 0.0 4.1 4.4 1.5 54.9 11.7 8.6 1.3 25.6 26.4 0.9 5.9 3.3 8.3 20.4 0.0 2.5 34.4 87.7 67.1 8.2 12.4 23.4 2.2 7.6 0.0 67.3 244.5 24.3 29.8 44.4 0.7 4.2 10.7 7.8 0.5 2.3 39.5 42.9 53.8 21.9 10.1 1.9 9.1 1.5 5.4 11.0 16.8 2.4 PHOSPHO2 MGC22679 ENSG00000144362 "Phosphatase, orphan 2" Q8TCD6 2 169694454-169701708 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 158.7;Spermatocytes: 68.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034726, HPA034727" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 1: Thyroid gland - Transcription" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles Nucleoplasm "HPA034726: AB_10602191, HPA034727: AB_2674302" "unprognostic (1.98e-1)" "unprognostic (1.22e-1)" "unprognostic (7.56e-2)" "unprognostic (1.39e-3)" "unprognostic (1.30e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (3.82e-6)" "unprognostic (4.31e-2)" "unprognostic (2.11e-2)" "unprognostic (5.19e-2)" "unprognostic (1.40e-1)" "unprognostic (2.31e-1)" "prognostic favorable (9.53e-4)" "unprognostic (4.10e-1)" "unprognostic (2.60e-1)" "unprognostic (6.12e-2)" "unprognostic (7.53e-2)" 5.0 2.8 1.9 2.4 1.9 2.9 10.6 4.1 1.6 4.7 3.7 5.8 6.4 5.3 4.2 3.2 6.0 4.0 2.7 1.6 2.8 5.6 3.6 3.3 3.0 1.4 1.8 6.0 5.1 7.2 4.6 3.0 1.5 13.0 5.8 7.2 8.5 4.7 3.4 3.5 6.4 3.1 1.7 2.5 4.7 13.7 2.4 3.0 9.8 1.6 3.0 3.8 2.8 1.9 6.6 1.8 4.6 6.2 8.5 2.7 17.8 2.8 1.9 4.3 4.7 6.3 4.9 6.4 6.1 2.1 8.9 5.0 6.2 3.4 3.5 9.5 7.0 6.4 6.1 11.0 5.6 5.3 5.6 4.9 6.3 4.9 6.5 3.6 3.9 8.9 10.8 6.4 2.7 6.0 3.7 6.8 6.0 4.2 2.3 3.6 2.8 5.1 6.8 19.6 19.1 6.5 5.8 3.1 6.8 5.5 8.4 3.2 2.3 4.7 4.3 4.2 3.1 6.2 6.0 5.7 5.5 3.2 5.1 0.1 0.7 1.0 3.3 0.9 4.6 6.5 3.6 3.2 0.9 8.8 4.7 4.6 1.3 9.8 0.9 4.2 4.4 1.4 1.9 1.9 4.1 1.6 1.6 2.8 1.4 1.8 1.5 1.7 2.4 1.9 6.1 3.2 3.6 0.0 6.8 2.5 10.3 5.4 2.8 8.7 15.2 11.0 4.1 5.7 4.7 3.7 6.2 8.8 2.5 7.0 9.8 7.6 158.7 10.6 5.0 4.3 15.0 6.9 0.0 11.1 9.3 6.9 15.3 3.3 0.0 5.7 2.5 3.7 2.8 6.7 0.0 6.6 12.2 0.6 1.6 35.9 4.7 2.0 3.6 0.0 1.0 6.4 1.0 0.0 0.0 6.4 6.8 4.9 3.8 6.5 12.7 12.2 13.4 10.2 0.0 6.7 9.3 68.9 13.9 4.5 4.3 5.5 5.7 8.8 7.5 5.5 PI15 P25TI ENSG00000137558 "Peptidase inhibitor 15" O43692 8 74824534-74855029 "Predicted secreted proteins" "Developmental protein, Protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 54.4;prostate: 31.0;smooth muscle: 49.9" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 36.8;Breast glandular cells: 73.2;Breast myoepithelial cells: 13.6;Prostatic glandular cells: 19.3;Smooth muscle cells: 36.2;Urothelial cells: 15.7" "Group enriched" "Detected in many" 7 "breast cancer: 11.1;melanoma: 8.6;prostate cancer: 18.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "AF22: 23.3;SH-SY5Y: 21.3;SK-MEL-30: 30.0;U-266/70: 7.9" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "spinal cord: 6.3" "HPA006593, HPA030057" Uncertain Approved Vesicles,Cytosol "Secreted in other tissues" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 35: Glandular cells - Unknown function" Vesicles Cytosol "HPA006593: AB_1078568, HPA030057: AB_10602143" "unprognostic (2.77e-1)" "unprognostic (1.57e-2)" "unprognostic (3.41e-1)" "unprognostic (1.88e-2)" "unprognostic (3.22e-1)" "unprognostic (3.24e-1)" "unprognostic (2.94e-2)" "unprognostic (2.33e-3)" "unprognostic (1.87e-1)" "unprognostic (2.25e-1)" "unprognostic (3.65e-2)" "unprognostic (1.85e-2)" "unprognostic (8.63e-14)" "unprognostic (2.54e-3)" "unprognostic (1.34e-1)" "unprognostic (2.60e-2)" "unprognostic (2.05e-2)" 5.8 1.1 0.6 54.4 0.8 0.0 22.1 0.1 1.6 11.0 0.0 7.8 0.2 19.8 2.1 2.5 20.9 1.5 1.8 0.9 0.9 0.9 0.2 2.2 0.6 0.7 0.8 6.3 0.3 0.0 0.5 0.3 0.4 31.0 4.6 0.6 2.0 6.8 0.4 0.4 4.6 49.9 1.1 1.3 0.7 0.5 2.4 0.4 0.6 0.2 0.2 8.3 6.5 0.6 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 1.1 21.3 0.0 0.1 30.0 0.4 0.5 0.5 0.0 0.0 0.5 0.0 0.1 7.9 3.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.1 1.6 0.9 0.9 0.7 0.8 0.4 1.1 2.4 0.6 0.2 0.0 0.0 2.3 0.1 0.1 36.8 0.0 0.6 0.2 73.2 13.6 0.5 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 1.6 0.2 9.1 2.5 0.0 0.0 4.3 0.0 0.4 3.9 0.5 0.3 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.6 1.9 0.9 0.2 3.6 1.0 0.0 0.0 0.0 0.5 2.0 0.0 0.0 0.0 0.1 19.3 0.0 0.1 0.0 0.5 0.0 1.7 36.2 0.0 0.0 0.4 0.0 0.1 0.4 0.0 0.0 15.7 PICALM "CALM, CLTH" ENSG00000073921 "Phosphatidylinositol binding clathrin assembly protein" Q13492 11 85957175-86069882 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" Endocytosis "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 500.3;Oligodendrocytes: 709.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 40.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019053, HPA019061" Enhanced Enhanced Vesicles NA NA 40000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA019053: AB_1855361, HPA019061: AB_1855362" "unprognostic (9.27e-3)" "unprognostic (7.29e-2)" "unprognostic (3.51e-1)" "unprognostic (6.83e-2)" "unprognostic (5.13e-2)" "unprognostic (1.93e-1)" "unprognostic (5.36e-3)" "unprognostic (9.02e-3)" "unprognostic (9.80e-2)" "unprognostic (6.27e-3)" "prognostic unfavorable (6.61e-4)" "unprognostic (4.31e-1)" "prognostic favorable (2.02e-6)" "unprognostic (1.26e-2)" "unprognostic (5.21e-3)" "unprognostic (2.52e-1)" "unprognostic (1.02e-1)" 183.5 62.5 97.1 120.4 162.1 111.4 111.5 119.3 118.7 86.4 43.8 86.3 106.3 79.3 52.4 109.1 66.1 127.0 87.9 91.7 110.8 168.5 147.0 99.4 82.7 125.2 130.7 94.4 80.6 120.6 36.5 157.2 131.6 73.1 83.1 71.5 62.3 93.6 75.8 74.2 115.5 135.3 106.0 126.5 73.0 64.9 120.7 93.1 75.7 101.9 96.7 139.5 73.5 194.7 167.0 78.4 121.1 85.9 185.5 188.8 228.5 211.7 274.7 164.4 143.0 310.7 222.4 126.0 210.8 342.6 171.1 134.6 129.4 154.2 232.8 38.6 45.0 364.9 101.5 98.9 185.6 87.2 158.3 166.6 161.7 308.7 253.3 275.1 178.7 85.9 239.1 103.0 305.2 98.2 103.9 76.8 66.9 269.0 42.7 69.8 182.2 91.1 312.5 139.2 72.9 58.7 258.4 85.4 68.7 156.5 115.6 67.0 196.9 298.6 104.1 355.0 170.2 36.7 107.1 118.4 70.8 64.6 206.6 6.4 13.5 7.5 5.7 11.7 4.9 3.1 4.2 8.0 11.4 2.1 4.2 4.0 40.6 7.1 12.5 3.9 6.4 5.3 97.1 162.1 119.3 118.7 91.7 110.8 125.2 130.7 131.6 106.0 120.7 194.7 147.1 35.3 58.9 134.5 33.3 116.0 44.4 33.0 30.1 20.8 34.8 28.6 46.4 42.9 34.3 71.7 12.5 42.9 43.9 64.2 31.3 57.7 59.3 32.3 32.8 98.7 25.1 88.8 144.7 37.6 127.1 44.6 34.1 50.9 48.2 23.2 71.4 52.3 85.0 40.4 140.7 30.1 30.5 142.8 229.2 95.4 35.8 127.4 60.5 500.3 92.1 22.6 32.0 188.0 709.3 90.2 55.3 43.6 39.1 49.5 71.4 84.0 41.0 16.3 78.9 36.4 92.7 17.3 14.1 34.4 96.5 41.3 38.9 23.6 30.6 77.7 PIGP "DCRC, DSCR5, DSRC" ENSG00000185808 "Phosphatidylinositol glycan anchor biosynthesis class P" P57054 21 37062846-37073170 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 350.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026921 Uncertain Approved Vesicles Yes No "Cluster 30: Non-specific - Translation" "Cluster 29: Non-specific - Vesicular transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "HPA026921: AB_1847874" "unprognostic (4.47e-3)" "unprognostic (9.45e-2)" "unprognostic (3.03e-1)" "unprognostic (2.40e-1)" "unprognostic (2.85e-2)" "unprognostic (1.92e-2)" "unprognostic (1.92e-2)" "unprognostic (5.54e-2)" "unprognostic (1.55e-1)" "unprognostic (1.22e-2)" "unprognostic (4.21e-3)" "unprognostic (1.12e-2)" "unprognostic (1.96e-2)" "unprognostic (1.93e-1)" "unprognostic (5.48e-2)" "unprognostic (1.02e-1)" "unprognostic (6.55e-2)" 33.9 41.3 18.7 12.5 20.2 9.1 35.4 22.4 24.7 22.9 24.8 24.2 19.0 18.3 107.2 16.8 25.7 22.5 40.1 18.1 22.8 35.9 54.7 21.6 16.6 22.8 21.6 27.9 41.4 51.9 38.0 20.9 22.6 33.7 27.4 28.6 32.2 26.7 44.0 12.4 15.5 17.1 22.1 14.9 22.8 36.5 20.0 22.0 36.3 42.8 19.7 26.2 13.2 25.4 25.9 11.5 23.7 14.8 41.5 28.6 16.9 21.9 38.7 18.6 21.1 15.4 53.7 37.1 45.7 32.0 81.4 19.4 22.7 25.5 18.5 37.4 36.1 86.2 13.8 21.3 26.3 26.9 16.6 26.5 47.2 33.4 43.0 42.2 35.1 80.5 50.7 61.8 38.5 16.5 32.9 25.5 19.6 76.8 27.9 31.0 12.1 37.0 48.2 13.3 49.2 29.8 61.4 43.0 81.8 33.6 35.2 53.2 18.3 12.9 6.6 14.8 19.3 81.1 96.5 42.0 38.1 30.5 43.4 0.4 13.5 3.7 19.6 20.3 24.8 34.2 25.1 21.6 20.9 28.1 33.3 29.0 1.9 16.8 22.6 30.9 20.6 15.6 18.7 20.2 22.4 24.7 18.1 22.8 22.8 21.6 22.6 22.1 20.0 25.4 37.4 28.9 41.8 9.8 37.0 33.0 58.9 88.9 35.3 21.2 74.1 86.4 82.4 42.9 65.1 44.1 10.4 60.7 29.4 21.6 90.1 61.8 79.3 67.0 35.9 31.3 44.9 25.7 6.9 71.3 52.4 48.9 30.1 49.3 15.9 32.2 35.3 79.8 66.7 16.8 8.7 63.9 65.1 57.6 39.9 75.6 69.0 44.1 37.4 2.8 50.2 37.0 23.7 7.5 18.2 57.7 50.3 35.0 54.3 45.6 52.3 97.1 86.9 33.6 65.7 32.7 44.6 350.8 177.5 44.2 26.3 52.3 31.7 62.6 53.1 63.7 PIGQ "GPI1, hGPI1" ENSG00000007541 "Phosphatidylinositol glycan anchor biosynthesis class Q" Q9BRB3 16 566995-584109 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 78.9;Late spermatids: 61.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039105, HPA039828, HPA061414" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 6: Erythroid cells - Oxygen transport" "Golgi apparatus, Vesicles" Nucleoplasm "HPA039105: AB_10796221, HPA039828: AB_10795158, HPA061414: AB_2684508" "unprognostic (1.23e-2)" "unprognostic (6.12e-3)" "unprognostic (2.81e-1)" "unprognostic (2.65e-2)" "unprognostic (1.09e-2)" "unprognostic (2.42e-1)" "unprognostic (9.58e-2)" "unprognostic (8.05e-2)" "unprognostic (2.12e-1)" "unprognostic (2.02e-1)" "unprognostic (3.02e-2)" "unprognostic (8.98e-2)" "prognostic favorable (2.53e-6)" "unprognostic (2.73e-1)" "unprognostic (2.60e-1)" "unprognostic (2.55e-1)" "unprognostic (2.80e-2)" 13.3 23.9 7.1 3.8 8.0 30.4 15.0 2.0 12.0 15.4 8.6 16.2 7.5 18.3 1.4 13.2 16.5 2.8 13.3 9.6 5.2 30.7 19.0 17.9 2.5 6.6 9.7 15.6 21.9 9.4 25.4 3.3 6.5 19.4 1.1 1.2 19.3 5.8 18.4 15.7 12.6 1.6 3.5 15.0 17.0 28.1 6.0 2.7 31.1 1.7 1.2 15.8 12.1 4.3 14.2 21.9 7.3 10.3 4.6 2.7 13.9 14.7 5.6 6.3 6.6 14.6 12.9 7.6 18.6 3.3 5.5 22.2 3.3 6.4 1.3 21.9 30.4 11.4 23.8 10.8 8.9 10.1 10.2 5.2 9.8 10.2 2.0 4.0 6.1 13.7 26.1 4.1 2.1 20.7 18.3 11.4 10.0 3.0 21.9 36.6 6.4 17.7 5.6 5.6 13.2 21.4 16.8 7.6 10.8 2.3 17.3 6.9 14.5 10.4 13.7 11.7 10.4 15.8 5.0 6.0 4.8 5.4 10.4 0.9 2.8 1.6 2.8 3.1 2.4 2.3 2.3 2.6 2.7 2.5 2.5 1.6 3.0 3.3 3.7 5.6 2.4 2.6 7.1 8.0 2.0 12.0 9.6 5.2 6.6 9.7 6.5 3.5 6.0 4.3 9.7 16.0 20.3 14.0 6.9 4.8 6.6 8.4 5.2 12.1 15.8 11.0 8.4 4.3 10.6 40.5 4.2 10.5 8.8 31.5 3.9 19.3 33.6 21.0 7.8 9.0 20.3 78.9 19.3 17.4 8.4 9.4 16.3 11.4 8.2 19.7 6.4 16.4 9.5 10.1 13.8 13.0 8.2 9.1 4.4 61.4 7.5 8.2 16.0 3.7 7.7 14.6 10.3 7.5 6.6 14.1 11.6 7.2 9.1 6.9 7.6 12.4 23.3 13.7 0.0 7.7 9.9 30.1 13.6 6.2 4.8 5.9 7.8 11.1 16.9 5.0 PIK3C2A PI3K-C2alpha ENSG00000011405 "Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha" O00443 11 17077730-17207983 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Endocytosis, Exocytosis" "Kinase, Transferase" "Cataract, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 217.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037641, HPA037642" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "Vesicles, Cytosol" "HPA037641: AB_10671878, HPA037642: AB_10697081" "unprognostic (2.35e-1)" "unprognostic (2.16e-2)" "unprognostic (3.71e-2)" "unprognostic (1.06e-1)" "unprognostic (1.63e-1)" "unprognostic (6.63e-2)" "unprognostic (2.47e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-2)" "unprognostic (1.86e-2)" "unprognostic (4.74e-2)" "unprognostic (1.84e-1)" "prognostic favorable (1.66e-4)" "unprognostic (3.20e-2)" "unprognostic (1.51e-1)" "unprognostic (1.18e-1)" "unprognostic (1.37e-1)" 22.5 13.7 16.3 12.3 25.9 9.4 15.9 22.5 14.6 16.1 17.4 13.2 14.9 18.0 15.7 15.4 14.5 19.0 12.4 10.5 14.0 23.5 15.5 16.6 11.3 16.6 16.1 14.1 12.3 43.6 10.3 23.1 17.0 16.4 13.0 22.4 11.8 14.8 6.4 12.3 11.8 18.3 13.8 13.0 18.0 19.3 19.6 9.4 30.7 12.1 10.9 14.9 12.0 15.8 53.8 24.1 39.6 24.8 28.0 28.3 35.3 33.2 35.7 23.9 33.2 58.9 6.0 15.6 16.2 28.6 39.1 34.8 31.9 25.4 42.1 13.5 27.6 9.8 28.4 23.3 30.6 12.3 14.9 22.2 17.5 23.6 45.8 22.2 57.7 9.9 23.4 14.7 18.6 16.6 6.6 7.7 22.6 30.1 18.5 6.9 41.1 11.0 29.6 47.0 23.2 20.5 50.6 21.4 23.2 33.0 12.7 12.3 72.5 19.1 27.4 50.1 20.4 5.9 14.1 12.8 22.8 11.3 22.6 1.7 1.5 1.1 1.7 1.0 1.1 1.4 1.3 1.3 2.1 1.5 1.7 1.0 2.3 1.8 3.2 1.4 0.9 0.6 16.3 25.9 22.5 14.6 10.5 14.0 16.6 16.1 17.0 13.8 19.6 15.8 93.2 76.9 62.0 217.4 25.0 35.3 26.1 18.7 24.5 49.1 34.7 25.0 29.7 25.8 33.1 36.8 70.9 29.6 29.5 22.6 19.6 19.8 35.9 51.8 35.1 87.6 28.7 11.2 57.0 25.1 17.9 28.6 45.3 72.4 32.2 22.8 106.7 32.4 19.2 35.3 81.1 23.5 18.3 46.3 33.1 18.6 25.7 27.0 19.6 69.3 19.6 73.0 17.5 62.8 79.4 26.1 13.1 31.2 29.9 42.7 15.2 22.4 26.4 40.4 39.5 33.7 35.1 52.6 26.8 23.5 34.0 143.5 25.3 25.1 20.7 37.3 PIK3CB PIK3C1 ENSG00000051382 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta" P42338 3 138652698-138834928 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Autophagy, Cell adhesion, Endocytosis" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 96.5;Inhibitory neurons: 92.4;Oligodendrocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEL: 115.2;HMC-1: 185.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031938, HPA042288, HPA064207" Approved Supported Nucleoplasm,Nucleoli,Vesicles,Midbody Yes No "Cluster 52: Eosinophils - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nucleoli, Vesicles, Midbody" "CAB031938: AB_2165408, HPA042288: , HPA064207: AB_2685212" "unprognostic (4.89e-2)" "unprognostic (1.42e-2)" "unprognostic (5.97e-2)" "unprognostic (7.85e-2)" "unprognostic (4.89e-2)" "unprognostic (6.01e-2)" "prognostic unfavorable (6.42e-4)" "unprognostic (3.98e-2)" "unprognostic (1.35e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.99e-5)" "unprognostic (2.15e-1)" "unprognostic (6.18e-3)" "unprognostic (9.33e-2)" "unprognostic (7.82e-2)" "unprognostic (2.79e-1)" "unprognostic (4.59e-2)" 11.6 7.4 4.3 12.4 5.0 23.7 11.9 8.6 8.6 12.4 14.4 17.8 17.8 8.2 7.0 18.0 12.1 10.3 15.8 5.4 4.4 26.4 11.0 11.2 12.3 5.1 3.3 9.2 22.3 19.3 2.7 18.6 6.1 15.0 18.1 23.0 19.8 12.0 19.5 23.7 17.9 9.1 3.5 10.8 13.0 8.0 4.0 17.0 43.2 13.2 13.2 9.9 5.4 7.9 64.1 21.9 11.7 9.4 10.6 13.0 79.2 14.2 14.5 15.1 16.7 26.0 25.2 25.0 38.0 13.7 29.1 27.5 15.1 24.1 27.3 31.8 12.5 115.2 14.8 17.3 11.8 30.1 185.1 12.4 17.6 10.2 21.9 26.4 21.5 12.3 43.0 19.0 18.1 28.6 17.8 20.7 16.6 49.2 19.5 11.5 12.2 19.6 24.5 35.5 9.8 7.4 37.6 18.0 56.2 34.7 44.8 73.0 20.3 8.4 11.7 21.2 21.1 30.3 22.1 23.7 22.8 27.7 14.0 4.4 5.1 6.9 2.4 2.8 1.6 2.8 2.8 1.8 5.9 2.6 3.5 2.4 6.4 0.8 2.8 1.0 1.5 2.0 4.3 5.0 8.6 8.6 5.4 4.4 5.1 3.3 6.1 3.5 4.0 7.9 19.7 9.6 21.3 40.1 12.1 19.1 18.7 12.5 14.2 16.2 13.1 7.7 37.3 12.8 18.3 18.4 25.0 35.5 6.9 30.3 5.9 11.1 1.1 18.3 4.0 13.9 16.3 8.0 96.5 19.4 61.1 7.3 21.4 18.8 14.5 6.7 9.7 19.1 14.4 21.9 92.4 17.1 4.1 33.3 23.1 1.7 3.7 28.1 7.2 37.5 29.5 8.9 11.3 48.2 88.2 20.0 25.9 6.8 10.2 25.8 21.9 23.4 17.4 19.5 6.6 8.6 5.9 16.0 19.9 22.1 23.3 47.9 11.6 4.2 15.1 17.5 PIK3CD p110D ENSG00000171608 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta" O00329 1 9651731-9729114 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Chemotaxis, Differentiation, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 60.9;lymphoid tissue: 50.4" "Cell type enhanced" "Detected in many" "dendritic cells: 44.0;granulocytes: 25.3;Kupffer cells: 35.2;Microglial cells: 29.0;NK-cells: 29.9;T-cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 153.3;NB-4: 65.9;REH: 68.9;THP-1: 65.4;U-937: 78.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015420, HPA044953" Enhanced Approved "Vesicles,Cytokinetic bridge" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Cytokinetic bridge" "CAB015420: AB_831654, HPA044953: AB_2679153" "unprognostic (5.73e-3)" "unprognostic (2.75e-3)" "unprognostic (8.93e-2)" "unprognostic (4.05e-2)" "unprognostic (4.71e-2)" "unprognostic (1.40e-2)" "unprognostic (2.13e-1)" "unprognostic (7.42e-2)" "unprognostic (2.78e-2)" "unprognostic (1.54e-2)" "unprognostic (3.46e-2)" "unprognostic (6.75e-2)" "unprognostic (8.65e-3)" "unprognostic (2.09e-1)" "unprognostic (1.34e-1)" "unprognostic (2.04e-1)" "unprognostic (6.78e-2)" 7.2 3.1 6.8 33.4 6.3 60.9 3.9 6.1 7.5 6.2 6.4 5.4 5.2 4.9 1.7 4.9 6.1 7.0 3.3 7.0 5.3 6.4 3.5 12.0 46.9 7.3 6.6 7.0 3.0 2.9 2.8 4.2 7.8 4.6 3.4 0.6 5.1 2.7 1.2 3.0 17.2 4.7 6.6 50.4 5.7 4.0 9.3 24.3 5.5 3.5 32.0 7.4 5.1 8.5 8.1 5.2 0.4 1.4 1.3 1.1 0.7 12.1 24.5 26.0 21.1 0.3 3.3 21.5 4.9 9.8 12.4 2.4 2.0 11.0 16.2 153.3 0.4 2.4 1.3 9.0 5.1 56.0 18.7 4.3 4.5 29.2 9.8 11.4 3.8 14.9 8.0 0.1 15.0 0.6 5.4 65.9 2.2 0.3 1.4 68.9 13.0 0.7 10.9 0.0 1.7 1.5 2.7 4.9 11.9 6.8 0.8 65.4 9.8 7.7 7.9 0.2 11.5 4.9 4.9 30.1 16.7 78.6 4.4 18.0 23.5 40.2 21.6 23.0 22.6 12.8 16.3 19.9 22.5 13.6 20.9 23.1 63.2 25.9 29.2 25.7 13.3 38.3 6.8 6.3 6.1 7.5 7.0 5.3 7.3 6.6 7.8 6.6 9.3 8.5 1.7 9.6 13.4 2.0 22.2 1.5 2.2 1.8 4.0 0.7 2.0 1.7 3.1 0.0 1.1 0.0 2.1 0.3 44.0 0.1 1.9 3.9 3.0 2.0 1.7 2.7 0.0 10.3 6.7 2.0 0.5 2.9 0.0 1.0 25.3 4.2 3.6 0.0 14.7 0.0 13.4 0.1 0.0 35.2 6.0 2.8 1.2 23.1 3.6 29.0 19.3 2.5 29.9 1.0 1.1 11.3 0.0 1.5 8.2 4.1 0.2 3.8 3.3 1.3 6.6 2.0 4.7 1.5 3.4 2.9 1.1 0.3 37.1 1.5 0.2 2.1 PIK3R3 p55 ENSG00000117461 "Phosphoinositide-3-kinase regulatory subunit 3" Q92569 1 46040140-46133036 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 199.0;Endothelial cells: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 5.8" "Group enriched" "Detected in many" 9 "granulocytes: 5.8;monocytes: 2.4;T-cells: 2.3" "Cell line enhanced" "Detected in all" "RT4: 76.1" "Low region specificity" "Detected in all" "HPA005751, HPA071988" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 15: RT4 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles Nucleoplasm "HPA005751: AB_1855350, HPA071988: AB_2686479" "unprognostic (1.98e-1)" "unprognostic (3.75e-3)" "unprognostic (8.04e-2)" "prognostic favorable (1.93e-4)" "unprognostic (6.32e-2)" "prognostic favorable (3.62e-4)" "unprognostic (4.88e-2)" "unprognostic (3.33e-3)" "unprognostic (4.16e-2)" "unprognostic (4.63e-2)" "unprognostic (1.05e-2)" "unprognostic (1.45e-1)" "unprognostic (9.99e-3)" "unprognostic (2.87e-2)" "unprognostic (9.74e-2)" "unprognostic (6.71e-2)" "unprognostic (8.22e-3)" 31.2 12.2 13.0 7.2 11.2 0.7 28.0 35.9 14.8 15.3 14.0 7.5 3.2 15.9 10.3 7.1 10.1 10.7 35.2 11.4 14.9 16.2 4.0 18.5 6.2 16.7 17.3 4.1 4.7 12.1 8.5 13.3 16.8 12.0 4.9 17.9 12.5 6.1 12.0 6.4 8.6 11.5 15.5 11.2 9.9 25.4 15.9 10.8 14.2 18.5 5.3 14.8 7.4 11.4 10.9 3.6 47.4 24.4 4.6 2.0 15.2 6.3 4.6 8.2 10.1 2.1 3.2 14.3 18.9 2.5 9.9 6.4 16.9 5.8 5.3 11.1 15.0 9.3 41.8 1.6 1.5 8.3 11.8 5.8 3.3 8.7 3.2 7.8 17.3 32.8 3.5 10.0 11.8 16.7 33.4 5.1 16.9 3.1 9.6 42.0 12.7 17.0 20.4 76.1 34.4 24.9 20.5 53.5 5.7 28.5 14.9 7.3 32.4 8.7 8.0 1.5 6.2 14.1 15.8 8.5 6.9 10.9 4.5 0.0 0.2 5.8 2.0 0.3 1.9 0.3 0.4 1.8 0.0 0.0 0.1 1.1 0.0 0.0 2.4 0.3 2.3 0.6 13.0 11.2 35.9 14.8 11.4 14.9 16.7 17.3 16.8 15.5 15.9 11.4 199.0 0.0 8.4 15.7 3.1 2.5 5.4 42.1 14.8 48.3 32.0 30.1 21.1 0.0 28.8 18.4 45.9 4.4 13.9 21.7 0.0 0.6 11.8 13.9 21.0 83.3 7.8 5.9 26.2 1.2 1.1 16.2 55.5 26.2 9.5 6.1 0.0 0.0 1.7 3.3 55.9 8.6 38.7 0.0 4.4 19.9 1.2 8.4 5.4 60.9 0.9 33.5 3.1 22.1 7.1 1.4 1.5 7.9 10.1 7.2 4.5 4.2 26.7 42.8 0.0 13.3 18.0 35.9 31.7 8.0 1.8 1.4 15.7 19.2 6.6 5.0 PIK3R4 "p150, VPS15" ENSG00000196455 "Phosphoinositide-3-kinase regulatory subunit 4" Q99570 3 130678934-130746829 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036032, HPA036033" Approved Approved Vesicles,Microtubules NA NA "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Vesicles Microtubules "HPA036032: AB_10610281, HPA036033: AB_2674911" "unprognostic (7.50e-2)" "unprognostic (3.90e-3)" "unprognostic (1.68e-1)" "unprognostic (4.05e-3)" "unprognostic (2.88e-1)" "unprognostic (1.28e-1)" "unprognostic (1.34e-1)" "unprognostic (1.21e-1)" "unprognostic (1.11e-1)" "unprognostic (2.67e-1)" "unprognostic (1.02e-3)" "unprognostic (7.26e-2)" "prognostic favorable (4.40e-6)" "unprognostic (8.25e-2)" "unprognostic (3.72e-1)" "unprognostic (2.27e-1)" "unprognostic (1.05e-1)" 8.8 8.5 3.7 7.8 4.2 8.9 10.0 5.2 4.9 9.4 5.6 8.2 7.5 10.1 7.9 8.0 9.1 7.2 7.6 4.1 4.5 10.5 21.2 9.6 9.4 3.2 3.6 12.4 6.9 17.6 6.1 9.7 3.8 9.8 8.1 16.5 7.6 9.6 7.3 7.8 8.0 10.4 3.8 10.0 7.5 11.4 3.2 11.4 13.1 8.6 10.4 9.0 6.5 7.1 20.7 12.9 18.5 13.4 26.6 21.1 12.8 15.0 17.9 20.2 23.3 16.7 17.1 24.2 18.4 15.2 16.1 28.7 30.7 23.3 31.6 14.7 11.3 19.7 13.8 11.7 12.2 30.3 9.5 14.7 16.4 21.7 13.6 12.6 19.0 13.8 23.3 11.9 18.1 18.1 24.9 9.2 23.3 18.6 12.4 17.2 21.4 21.9 13.2 16.7 17.0 12.4 21.6 13.4 15.3 21.5 18.6 13.1 15.2 15.5 13.3 17.6 12.2 13.8 13.5 31.2 17.0 11.3 14.7 9.7 5.3 7.0 6.3 6.0 9.3 5.6 5.7 4.7 6.9 3.5 6.6 6.0 4.4 8.5 6.6 2.4 6.8 5.3 3.7 4.2 5.2 4.9 4.1 4.5 3.2 3.6 3.8 3.8 3.2 7.1 8.3 6.4 8.7 18.6 8.8 3.8 3.9 5.7 10.8 8.1 5.7 4.7 7.7 8.6 9.6 11.0 14.6 5.6 7.2 5.5 1.9 5.0 4.4 8.9 7.5 8.9 3.0 9.2 28.5 5.8 3.4 6.9 13.3 9.9 9.5 9.5 7.5 18.2 5.9 5.0 30.3 6.8 8.2 6.4 2.6 3.1 9.6 7.3 5.4 20.6 7.1 9.0 6.2 22.1 32.9 6.6 4.3 11.7 6.9 4.8 6.2 4.2 12.6 12.6 6.6 8.9 6.2 17.0 13.9 9.5 4.4 4.2 7.5 9.6 6.1 3.4 PINLYP ENSG00000234465 "Phospholipase A2 inhibitor and LY6/PLAUR domain containing" A6NC86 19 43575801-43583964 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 23.5;Proximal tubular cells: 19.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 21.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 73.1;HMC-1: 46.6;JURKAT: 37.1;REH: 29.8;THP-1: 36.6" "Not detected" "Not detected" HPA061218 Uncertain Approved Vesicles "Secreted to blood" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 35: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA061218: AB_2684453" "unprognostic (6.72e-2)" "unprognostic (6.21e-2)" "unprognostic (4.72e-1)" "unprognostic (3.13e-2)" "unprognostic (2.46e-3)" "unprognostic (1.20e-1)" "unprognostic (1.20e-1)" "unprognostic (1.22e-2)" "unprognostic (5.07e-2)" "unprognostic (2.00e-1)" "unprognostic (2.85e-2)" "unprognostic (1.14e-1)" "unprognostic (4.36e-3)" "unprognostic (1.95e-2)" "unprognostic (1.68e-1)" "unprognostic (1.08e-1)" "unprognostic (3.60e-2)" 9.9 3.5 16.3 3.3 16.7 2.7 8.5 18.1 22.1 17.3 16.1 13.3 1.4 14.7 9.4 10.5 17.1 9.3 9.8 16.1 16.8 22.9 2.1 7.7 5.0 17.2 17.0 19.6 2.4 0.7 14.9 2.8 16.0 13.5 3.0 2.6 5.8 10.4 1.7 7.6 6.4 11.1 16.4 8.4 7.3 5.4 17.4 10.6 11.8 3.3 5.2 10.3 13.0 15.7 0.7 0.3 1.9 0.3 3.4 4.5 0.4 0.8 1.2 1.6 4.3 0.0 0.1 0.0 0.2 19.0 1.8 4.0 0.0 0.2 1.5 0.1 0.2 73.1 0.8 0.1 10.3 0.0 46.6 10.2 0.4 10.3 0.2 4.3 2.7 37.1 0.9 1.0 0.7 0.4 8.9 1.1 1.8 0.1 0.7 29.8 0.2 0.0 0.8 0.4 0.3 0.0 0.0 0.4 0.1 0.3 0.1 36.6 1.2 4.7 0.9 0.1 3.1 0.0 0.0 4.4 16.0 0.0 0.4 10.4 1.5 0.7 3.0 1.2 3.6 1.7 0.9 2.5 2.3 4.7 0.3 3.6 0.5 1.4 0.2 21.0 2.0 1.7 16.3 16.7 18.1 22.1 16.1 16.8 17.2 17.0 16.0 16.4 17.4 15.7 1.8 12.8 3.2 2.3 1.1 3.6 10.0 5.6 8.6 6.1 2.4 5.6 2.8 8.6 5.7 9.2 6.2 0.4 1.8 0.1 23.5 1.3 6.4 2.1 9.9 4.3 0.0 4.4 0.5 0.4 0.4 9.1 2.0 2.0 0.0 7.6 5.7 0.0 5.1 6.7 1.1 0.8 2.0 1.0 3.9 7.3 11.5 2.7 5.4 1.9 3.3 5.6 0.0 5.0 0.5 0.4 0.1 9.8 1.7 5.2 0.7 19.0 15.0 3.3 0.0 2.1 5.9 2.3 1.2 6.7 3.1 0.1 1.2 13.6 1.7 6.6 PIP5K1B "MSS4, STM7" ENSG00000107242 "Phosphatidylinositol-4-phosphate 5-kinase type 1 beta" O14986 9 68705240-69009176 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 97.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 127.4;Early spermatids: 100.0;Inhibitory neurons: 270.1;Muller glia cells: 120.2" "Group enriched" "Detected in many" 4 "colorectal cancer: 10.1;pancreatic cancer: 3.4;stomach cancer: 9.4;testis cancer: 3.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "eosinophil: 34.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 34.5" "Cell line enhanced" "Detected in some" "AF22: 43.8;HEL: 17.0;Hep G2: 13.4;OE19: 73.1;U-266/70: 17.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009687 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Vesicles "HPA009687: AB_1855391" "unprognostic (2.02e-3)" "unprognostic (1.84e-2)" "unprognostic (3.77e-2)" "unprognostic (2.72e-1)" "unprognostic (1.56e-1)" "unprognostic (1.62e-1)" "unprognostic (5.85e-3)" "unprognostic (1.80e-2)" "unprognostic (1.38e-2)" "unprognostic (1.17e-1)" "unprognostic (2.98e-2)" "unprognostic (2.92e-2)" "prognostic favorable (1.03e-9)" "unprognostic (2.10e-2)" "unprognostic (1.71e-1)" "unprognostic (1.19e-1)" "unprognostic (3.34e-1)" 4.2 11.9 5.6 6.0 5.3 16.1 4.9 18.4 8.1 6.3 97.3 31.2 34.8 7.5 1.7 1.2 6.0 4.0 32.2 12.3 10.7 7.8 0.3 12.9 2.6 7.9 11.2 1.0 8.6 13.7 6.6 6.5 6.3 3.1 29.1 38.0 16.4 9.6 2.9 2.3 30.8 2.9 4.0 2.6 26.1 24.7 11.4 1.0 1.2 5.1 3.6 3.3 2.5 3.7 0.0 0.0 43.8 0.0 0.1 0.0 8.5 0.0 0.0 0.0 0.0 4.6 0.0 3.6 0.1 0.0 0.1 0.1 0.4 0.1 0.0 0.0 0.8 17.0 0.3 13.4 0.0 0.9 4.4 0.0 2.0 0.0 0.0 0.0 0.1 0.5 0.9 9.3 0.3 1.1 0.1 0.2 2.3 73.1 1.4 1.4 0.1 0.3 0.3 3.4 0.9 0.1 0.0 0.1 0.5 1.0 0.2 0.1 0.1 0.0 0.4 0.1 0.0 17.0 3.5 2.3 0.0 3.1 0.0 5.6 0.5 34.5 0.0 0.0 0.0 4.7 0.3 0.1 0.1 5.4 0.7 0.1 1.7 0.0 0.2 1.4 1.6 0.3 5.6 5.3 18.4 8.1 12.3 10.7 7.9 11.2 6.3 4.0 11.4 3.7 3.6 35.3 34.4 28.7 19.2 0.6 3.2 0.5 0.6 5.1 4.7 3.3 61.6 2.8 2.8 5.5 2.1 21.3 0.0 127.4 27.4 1.6 100.0 12.8 13.6 3.3 37.0 53.6 84.7 14.0 1.3 3.1 40.2 27.5 5.7 3.8 1.4 0.0 3.9 0.0 270.1 32.6 14.2 1.0 1.3 47.6 2.5 5.6 5.4 60.0 2.6 120.2 0.0 80.9 6.4 5.2 46.6 1.5 43.2 2.5 39.2 1.4 6.5 3.3 26.3 2.5 32.2 39.0 4.5 0.7 0.3 8.8 2.1 0.9 29.7 9.8 PITPNA "PITPN, VIB1A" ENSG00000174238 "Phosphatidylinositol transfer protein alpha" Q00169 17 1517718-1562792 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 120.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000528 Uncertain Approved Vesicles,Cytosol NA NA 190000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" Cytosol Vesicles "HPA000528: AB_1079622" "unprognostic (1.54e-1)" "unprognostic (6.63e-2)" "unprognostic (2.43e-1)" "prognostic favorable (2.29e-4)" "unprognostic (7.88e-2)" "unprognostic (8.89e-3)" "unprognostic (2.37e-1)" "unprognostic (1.37e-1)" "unprognostic (7.33e-2)" "unprognostic (3.17e-2)" "prognostic favorable (1.80e-6)" "unprognostic (7.41e-2)" "prognostic favorable (9.35e-4)" "unprognostic (1.72e-1)" "unprognostic (1.23e-1)" "unprognostic (8.10e-2)" "unprognostic (6.81e-3)" 42.5 36.8 41.7 61.0 45.4 93.6 41.7 46.6 56.2 50.7 51.0 47.2 56.7 55.3 58.8 76.6 65.9 45.4 39.1 43.8 50.5 40.0 39.0 46.9 40.4 62.4 45.4 32.1 33.9 60.8 33.1 50.2 58.4 54.2 55.6 47.6 84.1 61.7 24.7 93.2 88.9 54.3 41.9 42.4 40.5 44.8 52.2 33.2 64.7 22.7 57.1 51.9 41.8 43.0 64.9 70.5 70.5 61.0 72.1 78.8 110.7 68.9 75.8 70.6 50.9 78.7 25.7 81.8 62.4 94.0 45.4 79.5 64.2 68.4 97.0 68.3 69.2 44.7 61.4 37.0 70.6 31.1 51.6 58.9 90.6 70.5 73.1 74.4 118.4 67.1 63.3 44.9 74.8 36.5 80.1 28.5 49.3 103.4 34.1 63.8 27.2 46.9 70.5 73.5 25.2 55.2 83.2 59.1 51.4 70.5 52.2 24.7 113.8 44.8 39.5 126.4 95.5 27.2 49.8 28.8 77.4 47.9 58.4 3.7 2.4 3.2 2.1 2.7 4.0 4.3 3.1 2.8 3.5 3.1 2.9 2.6 8.0 3.7 1.9 2.7 5.2 1.7 41.7 45.4 46.6 56.2 43.8 50.5 62.4 45.4 58.4 41.9 52.2 43.0 29.3 35.3 35.0 28.7 14.1 31.0 17.5 12.0 12.0 36.4 30.0 30.2 23.9 17.2 17.1 25.8 8.4 43.4 26.9 41.2 13.7 16.0 12.0 50.5 48.4 31.4 22.1 15.6 42.4 18.5 47.3 19.1 13.3 36.5 19.0 16.8 34.6 30.2 40.5 40.4 46.3 27.7 10.2 29.9 49.7 16.8 12.5 36.4 19.6 36.5 36.6 40.2 13.4 12.1 16.0 26.0 22.9 21.8 15.7 33.0 78.0 16.3 21.7 18.4 6.6 18.8 45.1 35.8 34.7 37.8 41.8 120.0 14.9 24.7 25.3 27.0 PITPNB VIB1B ENSG00000180957 "Phosphatidylinositol transfer protein beta" P48739 22 27851669-27920134 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000528 Uncertain Approved Vesicles,Cytosol NA NA 300000 "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" Cytosol Vesicles "HPA000528: AB_1079622" "unprognostic (9.29e-2)" "unprognostic (1.64e-1)" "unprognostic (4.59e-2)" "unprognostic (1.41e-1)" "unprognostic (1.41e-1)" "prognostic unfavorable (5.28e-4)" "unprognostic (1.34e-1)" "unprognostic (7.52e-3)" "unprognostic (4.78e-2)" "unprognostic (8.22e-3)" "unprognostic (1.56e-3)" "unprognostic (2.42e-1)" "unprognostic (5.66e-2)" "unprognostic (2.26e-1)" "unprognostic (6.28e-2)" "unprognostic (2.89e-2)" "unprognostic (1.64e-1)" 42.2 27.1 27.9 33.3 30.4 21.6 33.0 30.9 34.1 31.7 22.6 53.1 21.9 31.5 28.6 52.5 29.3 35.4 35.8 32.2 31.6 25.2 56.9 32.1 34.6 29.5 31.8 30.0 28.3 24.0 22.5 49.2 30.5 27.5 30.1 18.1 24.7 37.0 21.3 30.3 28.1 44.2 29.1 27.7 35.3 19.4 31.9 33.4 24.8 21.7 41.1 54.2 36.6 30.5 94.1 39.8 71.5 53.8 62.3 74.7 54.5 88.8 77.4 95.5 91.7 63.4 43.1 64.7 46.0 86.0 70.5 96.6 103.0 88.7 133.2 111.1 97.4 66.1 62.0 58.5 66.9 152.5 102.6 67.2 85.0 115.7 119.6 62.9 94.4 44.8 95.3 130.5 88.5 50.0 64.9 74.7 54.4 97.8 52.1 81.6 112.9 95.6 79.1 87.6 83.6 104.7 60.8 72.7 75.7 75.9 39.4 53.7 93.2 94.9 138.9 72.9 94.2 53.0 66.7 125.2 81.6 74.1 82.2 36.0 18.6 18.6 30.9 21.7 34.0 35.2 29.7 32.3 24.9 30.9 28.4 28.0 16.7 27.4 21.2 22.2 40.8 26.0 27.9 30.4 30.9 34.1 32.2 31.6 29.5 31.8 30.5 29.1 31.9 30.5 97.0 28.9 32.4 57.8 44.3 96.0 128.9 40.8 65.4 24.1 37.4 33.4 57.8 35.8 48.4 31.3 14.6 39.7 45.9 26.1 37.2 49.0 21.4 55.4 72.5 62.4 25.2 15.8 51.8 50.2 52.3 65.9 32.6 79.8 21.5 37.0 30.7 45.8 27.3 32.0 45.7 26.7 24.4 23.6 42.2 6.9 32.0 35.1 26.6 68.4 55.6 17.4 48.4 60.8 67.0 66.7 21.1 48.2 54.2 97.5 17.2 29.6 22.8 16.1 26.3 57.9 76.7 44.0 35.4 60.9 82.1 48.6 42.3 46.9 24.0 112.9 PITPNM1 "DRES9, NIR2, PITPNM, Rd9, RDGB, RDGB1, RDGBA1" ENSG00000110697 "Phosphatidylinositol transfer protein membrane associated 1" O00562 11 67491768-67506263 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Distal enterocytes: 69.9;Endometrial ciliated cells: 63.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HDLM-2: 91.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060227 Approved Supported Vesicles,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Vesicles "HPA060227: AB_2684226" "unprognostic (1.13e-1)" "unprognostic (1.90e-1)" "unprognostic (1.69e-2)" "unprognostic (1.71e-1)" "unprognostic (2.83e-2)" "unprognostic (8.68e-2)" "unprognostic (8.16e-2)" "unprognostic (4.55e-2)" "unprognostic (1.77e-1)" "unprognostic (2.26e-2)" "unprognostic (4.61e-1)" "unprognostic (3.27e-2)" "unprognostic (2.32e-2)" "unprognostic (1.14e-2)" "unprognostic (1.58e-1)" "unprognostic (4.62e-2)" "unprognostic (5.69e-2)" 10.6 24.5 19.6 24.3 12.6 26.8 6.4 6.1 23.2 10.7 13.9 14.4 18.7 9.3 2.4 19.5 23.1 9.0 22.3 13.3 23.8 37.8 11.0 16.3 27.6 14.2 31.0 4.0 9.8 10.3 26.7 8.0 13.5 10.4 7.5 40.7 8.7 10.3 6.9 5.0 21.1 5.9 2.3 21.6 16.0 8.8 51.5 17.4 15.7 18.4 17.2 16.2 9.3 5.5 12.7 31.2 18.8 13.9 20.3 12.1 30.5 12.2 21.5 14.8 8.4 28.5 22.6 12.5 28.7 17.5 28.4 32.4 14.5 27.0 4.8 91.0 6.0 17.0 55.8 10.8 16.0 19.4 35.3 15.0 17.0 22.4 14.7 27.4 17.9 18.7 13.2 11.0 12.5 19.1 33.2 45.6 19.3 35.9 13.5 23.7 6.0 17.3 24.4 25.1 18.1 11.5 27.3 37.6 29.6 9.0 7.4 16.9 17.7 26.5 20.1 16.9 8.9 16.0 8.3 11.2 37.1 22.7 10.6 0.0 1.4 0.9 1.1 3.3 1.0 0.7 0.8 1.0 1.0 0.5 0.3 0.8 1.4 0.1 2.7 0.4 0.7 1.1 19.6 12.6 6.1 23.2 13.3 23.8 14.2 31.0 13.5 2.3 51.5 5.5 7.5 3.2 5.8 2.0 10.8 8.2 6.3 9.3 13.6 45.7 5.4 5.2 8.4 5.7 9.7 20.2 64.6 4.6 10.6 69.9 3.9 11.3 6.1 63.3 16.5 4.9 11.4 0.4 5.1 9.3 8.9 4.2 34.7 24.6 2.5 7.1 3.3 3.4 8.4 38.7 6.6 16.8 10.2 13.2 14.0 17.0 2.1 15.2 3.6 10.3 13.5 20.7 3.1 0.5 0.5 15.9 32.7 1.2 7.5 9.8 39.0 18.9 37.8 53.7 0.0 6.3 9.8 1.4 5.5 11.2 3.3 15.2 14.9 1.4 24.0 19.4 PITPNM2 "NIR3, RDGB2, RDGBA2" ENSG00000090975 "Phosphatidylinositol transfer protein membrane associated 2" Q9BZ72 12 122983480-123150015 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "lymphoid tissue: 87.3" "Cell type enhanced" "Detected in many" "Astrocytes: 33.6;Cone photoreceptor cells: 54.2;Excitatory neurons: 51.3;Horizontal cells: 40.4;Inhibitory neurons: 41.3;Late spermatids: 87.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "NK-cell: 1.9" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEL: 29.5;JURKAT: 35.6;MOLT-4: 55.0;WM-115: 25.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003414, HPA003978" Approved Supported Vesicles NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA003414: AB_1855410, HPA003978: AB_1855411" "unprognostic (2.43e-1)" "unprognostic (9.29e-2)" "unprognostic (2.00e-1)" "unprognostic (5.39e-2)" "unprognostic (2.14e-1)" "unprognostic (6.76e-2)" "unprognostic (2.26e-2)" "unprognostic (1.08e-1)" "unprognostic (2.55e-1)" "unprognostic (6.44e-2)" "unprognostic (1.03e-1)" "unprognostic (9.28e-2)" "unprognostic (1.50e-3)" "unprognostic (7.66e-2)" "unprognostic (1.16e-1)" "unprognostic (1.19e-2)" "unprognostic (9.99e-2)" 4.6 9.0 11.4 4.6 12.3 5.2 3.7 6.7 15.6 6.1 18.7 5.7 4.7 4.6 3.7 4.7 3.7 2.6 4.9 13.1 1.8 8.7 11.0 6.8 3.2 4.9 3.6 15.3 3.5 6.6 8.4 3.6 1.6 3.5 2.5 15.2 2.4 3.8 5.0 4.1 4.9 5.7 0.4 4.4 4.6 7.3 4.9 87.3 3.7 3.3 1.9 7.0 4.9 3.8 4.6 8.7 2.8 4.1 1.9 3.7 16.8 0.7 1.1 2.3 1.2 3.8 3.7 0.0 3.7 1.5 4.8 12.8 2.3 2.2 0.8 0.3 2.8 29.5 5.7 10.5 1.3 1.1 6.0 1.8 3.8 3.0 2.3 10.8 4.5 35.6 6.8 0.3 2.9 2.9 55.0 6.1 3.2 1.4 3.9 15.7 0.2 11.4 4.1 4.7 2.5 0.9 6.3 5.2 4.1 1.6 1.1 3.1 13.3 3.3 3.7 5.4 5.1 0.8 1.0 20.4 8.2 2.2 25.4 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.2 0.6 0.0 0.2 0.5 0.4 0.0 1.9 0.0 0.0 0.3 0.7 11.4 12.3 6.7 15.6 13.1 1.8 4.9 3.6 1.6 0.4 4.9 3.8 16.2 0.0 5.0 33.6 2.8 3.6 0.7 0.7 2.2 19.6 1.5 1.5 7.3 2.8 1.6 9.2 54.2 1.3 6.3 6.3 1.9 3.3 33.0 3.7 3.6 9.3 0.0 1.7 51.3 4.5 6.5 3.8 2.0 5.2 1.3 0.8 6.4 16.3 0.5 40.4 41.3 3.7 0.0 0.6 1.1 87.7 1.8 3.6 1.8 10.3 1.3 3.7 10.3 22.1 1.8 3.9 0.3 4.9 2.2 1.1 6.1 2.6 0.1 15.8 0.0 2.1 2.5 8.2 4.7 3.6 1.6 3.7 4.8 0.4 2.6 0.6 PKN3 "PKNbeta, UTDP4-1" ENSG00000160447 "Protein kinase N3" Q6P5Z2 9 128702503-128720916 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 27.1;Breast glandular cells: 15.3;Endothelial cells: 17.9;Microglial cells: 13.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 78.0;REH: 42.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA045390, HPA058305" Uncertain Approved Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 30: Mammary glandular cells - Lactation" Vesicles "HPA045390: AB_2679308, HPA058305: AB_2683674" "unprognostic (4.36e-2)" "unprognostic (5.70e-2)" "unprognostic (2.68e-2)" "unprognostic (7.62e-2)" "unprognostic (2.23e-1)" "unprognostic (2.65e-2)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.78e-1)" "unprognostic (3.68e-1)" "unprognostic (1.48e-1)" "unprognostic (7.91e-2)" "unprognostic (8.73e-3)" "unprognostic (6.18e-3)" "unprognostic (9.99e-2)" "unprognostic (7.23e-2)" "unprognostic (2.36e-1)" 12.6 2.7 6.1 2.6 5.8 2.6 13.2 7.3 6.8 6.3 4.7 5.1 4.7 7.6 0.6 5.2 7.0 2.3 15.9 5.0 5.2 9.0 4.1 11.1 2.1 6.1 5.9 2.8 5.3 2.2 1.8 3.3 6.0 5.4 0.9 0.1 11.5 2.0 3.6 5.4 6.2 2.8 5.4 9.5 7.0 2.6 7.2 2.8 6.9 3.4 1.1 6.9 6.3 5.3 2.9 14.1 11.3 17.2 0.1 0.3 27.7 8.7 2.7 12.6 13.0 0.1 10.1 0.1 8.4 4.7 2.6 19.0 13.8 2.1 2.9 9.0 26.0 17.1 78.0 20.5 2.1 2.1 3.0 0.6 0.7 6.8 1.9 2.7 25.1 5.0 39.6 1.9 2.3 26.9 2.6 9.2 10.5 13.1 4.1 42.4 21.3 3.8 5.3 1.7 1.9 8.5 6.6 3.5 6.5 6.1 12.3 13.6 21.9 0.1 10.3 20.0 6.7 6.2 2.9 5.7 1.6 2.2 8.0 0.0 0.0 0.3 0.1 0.1 0.3 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.2 0.0 6.1 5.8 7.3 6.8 5.0 5.2 6.1 5.9 6.0 5.4 7.2 5.3 27.1 0.0 2.0 0.3 1.2 1.0 1.7 1.7 3.4 0.2 15.3 3.6 1.8 4.3 2.1 0.0 0.0 2.2 2.0 1.5 0.0 1.9 0.2 2.2 1.1 17.9 0.0 5.0 0.3 2.6 6.1 1.8 5.1 4.9 0.0 5.0 9.3 0.4 1.9 0.0 0.2 1.7 0.0 0.8 2.3 0.9 1.5 0.8 0.0 13.1 1.2 0.3 4.1 0.0 0.1 3.3 1.5 0.7 1.6 1.1 2.6 0.6 0.5 0.2 0.0 0.7 1.3 2.8 6.6 2.8 1.0 1.4 1.9 1.4 2.5 1.7 PLA2G15 "GXVPLA2, LLPL, LYPLA3" ENSG00000103066 "Phospholipase A2 group XV" Q8NCC3 16 68245304-68261058 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid degradation, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 58.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 116.0;Horizontal cells: 38.7;Kupffer cells: 37.1;Syncytiotrophoblasts: 50.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041702, HPA041727" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 38000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "HPA041702: AB_10794486, HPA041727: AB_10793931" "unprognostic (3.47e-2)" "unprognostic (9.99e-2)" "unprognostic (1.54e-3)" "unprognostic (6.84e-3)" "unprognostic (1.38e-2)" "unprognostic (1.65e-2)" "unprognostic (4.12e-3)" "unprognostic (3.16e-1)" "unprognostic (2.12e-2)" "unprognostic (1.84e-2)" "unprognostic (2.56e-1)" "unprognostic (9.29e-2)" "unprognostic (2.45e-3)" "unprognostic (2.98e-2)" "unprognostic (5.40e-3)" "unprognostic (6.28e-2)" "unprognostic (3.47e-2)" 15.1 11.5 12.9 7.6 12.5 7.0 9.8 12.8 18.1 6.6 9.2 8.0 6.9 6.2 8.7 6.2 7.4 9.3 35.5 13.1 14.2 33.4 17.3 17.5 13.6 13.1 14.1 7.7 7.4 11.4 11.4 27.3 14.6 8.1 5.9 4.4 9.1 5.7 58.3 13.9 6.5 8.8 12.4 20.3 8.4 10.8 15.9 11.7 13.2 22.4 5.1 8.8 6.4 16.1 10.0 10.0 7.9 25.5 36.7 26.8 19.0 24.6 31.6 35.7 30.2 26.1 18.6 17.4 31.2 34.1 28.5 15.2 8.5 10.4 15.9 6.0 16.4 5.0 10.4 19.0 19.6 4.6 25.0 19.0 11.2 35.2 5.5 44.6 22.5 8.9 7.9 9.8 23.0 21.3 7.2 14.5 5.1 9.4 12.1 9.9 11.3 55.3 17.7 8.7 3.0 5.1 31.2 9.6 19.2 6.6 25.2 23.7 18.8 31.5 15.0 41.1 16.5 34.6 33.5 22.1 28.6 13.8 12.0 19.6 24.1 16.0 4.7 27.5 4.8 5.0 5.2 7.0 14.1 5.3 6.5 5.5 1.0 2.3 32.4 12.2 5.1 14.6 12.9 12.5 12.8 18.1 13.1 14.2 13.1 14.1 14.6 12.4 15.9 16.1 4.4 6.4 3.3 3.6 3.0 4.8 2.4 6.8 2.8 12.1 7.0 6.0 22.5 1.5 5.1 9.2 8.4 20.9 4.9 8.1 5.9 10.1 1.9 4.3 4.8 5.9 0.0 1.7 7.0 7.2 7.6 8.2 8.6 9.0 15.2 6.6 9.3 13.7 116.0 38.7 6.7 8.5 2.0 37.1 6.8 6.1 2.1 21.4 12.4 10.3 7.7 4.4 3.1 5.5 3.9 6.3 5.0 1.5 2.6 2.6 3.0 19.5 2.7 6.1 0.0 5.5 6.7 3.4 2.8 4.1 3.4 50.8 3.9 3.1 4.1 2.0 PLA2G4A "cPLA2-alpha, PLA2G4" ENSG00000116711 "Phospholipase A2 group IVA" P47712 1 186828949-186988981 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Glycerol metabolism, Leukotriene biosynthesis, Lipid biosynthesis, Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 87.2;seminal vesicle: 48.3" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 33.4;Glandular and luminal cells: 28.1;Microglial cells: 115.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 6.8;eosinophil: 7.8;intermediate monocyte: 8.4;myeloid DC: 7.7;non-classical monocyte: 4.0;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 7 "dendritic cells: 7.7;granulocytes: 7.8;monocytes: 8.4" "Cell line enhanced" "Detected in many" "HeLa: 52.4;OE19: 84.4;RPMI-8226: 73.4;U-2197: 66.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010050, HPA050062, HPA054206" Approved Supported Vesicles,Cytosol NA NA 35000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" Cytosol Vesicles "CAB010050: AB_631312, HPA050062: AB_2681002, HPA054206: AB_2682417" "prognostic favorable (9.07e-4)" "unprognostic (1.18e-1)" "unprognostic (2.03e-1)" "prognostic favorable (2.85e-4)" "unprognostic (5.55e-2)" "unprognostic (1.51e-3)" "unprognostic (2.67e-2)" "unprognostic (2.43e-1)" "unprognostic (2.63e-1)" "unprognostic (7.14e-3)" "unprognostic (1.50e-1)" "unprognostic (1.68e-1)" "unprognostic (2.96e-2)" "unprognostic (8.07e-2)" "unprognostic (1.58e-1)" "unprognostic (1.90e-2)" "unprognostic (4.26e-2)" 9.9 12.7 2.4 6.3 3.4 4.8 6.5 2.8 3.7 14.5 3.2 11.9 11.1 10.2 11.7 7.5 24.9 6.2 6.3 2.4 3.3 10.8 2.1 5.9 5.3 4.4 3.5 6.4 7.6 87.2 2.0 5.8 4.0 8.8 8.1 0.8 6.3 48.3 0.5 9.5 8.2 10.5 4.1 6.6 5.3 2.8 3.1 1.5 2.6 2.1 2.9 29.1 8.4 3.9 0.0 39.7 0.2 0.0 23.8 9.5 0.0 1.5 15.1 1.8 3.2 0.3 15.5 0.0 0.0 0.0 6.8 2.8 24.6 7.4 0.8 12.5 0.6 7.6 52.4 0.0 14.7 11.1 3.8 5.4 5.0 19.5 4.0 2.4 16.5 3.4 16.7 5.9 0.0 0.0 0.0 0.0 2.1 84.4 5.1 0.0 0.0 73.4 0.1 5.4 0.2 0.0 5.9 2.0 7.3 0.7 0.8 15.0 3.3 14.3 1.9 66.3 3.2 2.3 0.0 0.0 5.3 32.4 20.7 0.2 6.8 7.8 0.0 8.4 0.2 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.6 1.1 4.0 3.1 0.0 1.7 2.4 3.4 2.8 3.7 2.4 3.3 4.4 3.5 4.0 4.1 3.1 3.9 0.6 0.0 1.1 0.3 0.2 21.4 4.3 4.6 10.2 0.2 2.9 2.9 2.3 0.0 4.9 0.0 0.0 0.1 3.2 1.6 1.9 2.1 0.9 33.4 1.7 6.6 1.2 3.0 8.1 0.0 0.1 11.2 7.1 28.1 10.8 3.3 1.1 0.2 6.6 0.0 5.8 2.6 2.0 7.9 8.3 1.3 10.5 11.5 5.4 115.2 3.7 0.0 1.0 2.0 0.4 1.7 7.3 14.7 0.0 2.3 2.0 0.3 2.3 0.5 0.0 1.2 5.0 0.6 0.3 5.2 8.9 0.0 1.0 1.2 4.8 13.4 PLA2G4E FLJ45651 ENSG00000188089 "Phospholipase A2 group IVE" Q3MJ16 15 41981582-42051190 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 17.2" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 12.9;Basal keratinocytes: 18.1;Suprabasal keratinocytes: 44.9" "Cancer enhanced" "Detected in some" "head and neck cancer: 11.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041105, HPA072562" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 31: Skin - Epidermis development" "Cluster 28: Keratinocytes - Keratinization" "Vesicles, Cytosol" "HPA041105: AB_2677300, HPA072562: " "unprognostic (2.98e-1)" "unprognostic (5.52e-1)" "unprognostic (2.60e-1)" "unprognostic (5.99e-2)" "unprognostic (5.12e-2)" "unprognostic (1.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.77e-1)" "unprognostic (4.22e-2)" "unprognostic (2.43e-1)" "unprognostic (1.22e-1)" "unprognostic (1.83e-7)" "unprognostic (1.81e-1)" "unprognostic (2.68e-1)" "unprognostic (7.48e-2)" "unprognostic (4.67e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 17.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 18.1 0.3 1.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.1 5.1 0.5 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.7 5.4 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 44.9 0.0 0.1 0.0 0.2 0.7 PLA2G4F PLA2G4F/Z ENSG00000168907 "Phospholipase A2 group IVF" Q68DD2 15 42139034-42156636 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skin 1: 78.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 74.5;Distal enterocytes: 21.7;Gastric mucus-secreting cells: 18.3;Glandular and luminal cells: 17.1;Suprabasal keratinocytes: 13.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "OE19: 11.1;RT4: 8.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA042713, HPA056752" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 11: Alveolar cells - Smell perception" Vesicles Nucleoplasm "HPA042713: AB_10793982, HPA056752: AB_2683226" "unprognostic (1.99e-1)" "unprognostic (6.21e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (1.06e-2)" "unprognostic (2.32e-3)" "unprognostic (1.48e-2)" "unprognostic (5.85e-2)" "unprognostic (2.25e-1)" "unprognostic (4.79e-2)" "unprognostic (6.65e-2)" "unprognostic (1.21e-2)" "unprognostic (9.32e-2)" "unprognostic (1.11e-1)" "unprognostic (4.55e-2)" "unprognostic (1.63e-1)" 0.0 0.0 0.1 0.4 0.3 0.3 2.4 0.1 0.1 5.7 0.0 6.4 6.7 0.0 1.6 5.7 0.1 0.1 0.3 0.1 0.0 7.8 0.2 12.2 0.1 0.0 0.0 0.0 0.1 2.9 1.7 0.1 0.0 4.3 3.8 0.2 2.6 0.4 2.9 78.1 4.2 0.1 0.0 0.1 2.4 0.1 0.0 4.4 1.9 0.5 0.3 1.2 11.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.1 0.0 11.1 0.1 0.0 0.0 0.0 0.0 8.3 0.4 0.0 0.0 0.8 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 74.5 0.0 0.0 5.5 2.7 1.3 0.6 0.0 1.2 0.3 2.9 0.0 0.5 5.5 0.0 1.7 0.0 21.7 3.9 0.4 0.0 7.3 1.0 0.1 0.0 0.0 0.0 1.3 0.7 0.1 18.3 17.1 2.5 0.0 0.0 0.0 0.1 0.0 0.0 7.7 4.1 0.0 0.3 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 6.3 0.0 0.3 3.1 10.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 5.6 13.8 1.2 0.6 0.0 6.7 2.0 PLAC1 "CT92, OOSP2B, OOSP2L" ENSG00000170965 "Placenta enriched 1" Q9HBJ0 X 134565838-134764322 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 29 "placenta: 27.9" "Cell type enhanced" "Detected in some" "Fibroblasts: 24.5;Leydig cells: 5.6;Peritubular cells: 7.9;Spermatocytes: 6.5;Spermatogonia: 11.0;Syncytiotrophoblasts: 10.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 20.1;hTCEpi: 15.6;hTERT-HME1: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000163, HPA063425" Enhanced Approved Vesicles,Cytosol "Secreted in female reproductive system" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Vesicles Cytosol "HPA000163: , HPA063425: AB_2685012" "unprognostic (2.93e-1)" "unprognostic (2.50e-3)" "unprognostic (2.89e-4)" "unprognostic (1.35e-7)" "unprognostic (3.83e-3)" "unprognostic (2.07e-2)" "unprognostic (1.63e-2)" "unprognostic (1.26e-1)" "unprognostic (2.01e-1)" "unprognostic (4.28e-2)" "unprognostic (1.48e-2)" "unprognostic (2.87e-2)" "unprognostic (3.33e-16)" "unprognostic (7.64e-3)" "unprognostic (4.03e-2)" "unprognostic (1.61e-1)" "unprognostic (1.91e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 27.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.9 0.0 1.2 0.0 0.2 1.2 0.3 0.4 1.1 0.0 2.0 0.3 0.1 1.8 0.3 0.5 20.1 0.0 0.1 0.3 2.3 0.0 0.0 0.9 15.6 0.1 6.3 0.1 2.4 0.2 0.1 1.7 0.1 1.0 0.0 0.3 0.0 1.3 2.6 0.0 0.3 3.7 0.0 0.0 3.0 0.0 0.0 3.7 0.7 2.2 0.1 0.0 0.0 0.5 0.8 0.2 0.0 0.4 0.1 0.3 0.2 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.9 0.0 0.0 1.3 0.0 2.8 24.5 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.9 0.0 0.0 0.0 0.0 0.7 5.6 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.5 0.1 0.0 7.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 11.0 0.0 0.0 10.7 0.0 2.1 0.0 0.0 PLAGL1 "LOT1, ZAC" ENSG00000118495 "PLAG1 like zinc finger 1" Q9UM63 6 143940300-144064599 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 252.3" "Cell type enhanced" "Detected in many" "Fibroblasts: 143.6;Leydig cells: 138.5;Theca cells: 205.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 99.0;RH-30: 94.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055706 Supported "Nuclear bodies,Golgi apparatus,Vesicles" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 33: Fibroblasts - ECM organization" "Nuclear bodies" "Golgi apparatus, Vesicles" "HPA055706: AB_2682893" "unprognostic (4.74e-3)" "unprognostic (8.35e-3)" "unprognostic (5.43e-2)" "unprognostic (1.74e-3)" "unprognostic (5.09e-2)" "unprognostic (1.95e-1)" "unprognostic (9.32e-2)" "unprognostic (6.17e-2)" "unprognostic (3.49e-2)" "unprognostic (5.02e-2)" "unprognostic (1.78e-3)" "unprognostic (2.07e-1)" "prognostic unfavorable (4.94e-6)" "prognostic unfavorable (6.61e-4)" "unprognostic (4.69e-2)" "unprognostic (5.17e-3)" "unprognostic (4.93e-3)" 37.7 74.8 4.1 18.5 5.2 21.7 29.6 1.9 7.0 31.4 5.8 28.8 9.6 29.5 9.0 32.9 20.8 26.9 26.4 3.8 2.9 17.0 3.6 26.7 12.1 3.6 4.1 36.5 27.7 9.5 81.6 252.3 3.9 26.0 21.3 1.6 30.1 12.1 12.2 61.9 20.6 19.7 3.2 15.6 26.9 8.7 6.0 6.6 13.8 22.3 12.1 39.6 34.4 4.0 0.2 5.0 99.0 0.1 39.4 78.0 0.3 32.9 21.6 16.1 33.5 0.3 6.0 2.7 16.0 30.4 4.0 0.0 0.8 12.0 32.2 3.1 4.4 45.2 58.7 0.9 13.9 40.9 8.9 60.5 4.6 15.8 13.8 23.4 33.5 16.1 4.4 0.8 18.0 6.2 16.9 19.8 17.2 0.0 3.7 20.7 94.1 0.1 33.1 1.1 8.7 10.3 51.0 0.1 0.1 29.6 0.1 50.1 19.8 0.2 35.2 77.7 36.4 9.1 9.0 0.6 25.3 16.6 2.0 4.9 12.0 25.1 1.4 9.1 1.4 3.7 1.3 1.9 14.9 5.8 0.9 1.5 21.7 2.2 2.9 6.7 2.0 3.8 4.1 5.2 1.9 7.0 3.8 2.9 3.6 4.1 3.9 3.2 6.0 4.0 19.5 51.3 51.0 28.4 15.2 21.7 14.6 5.3 34.1 2.1 16.8 14.0 8.4 5.7 12.6 5.5 0.0 4.6 19.0 16.1 7.9 11.8 1.8 8.6 91.9 23.8 16.7 19.3 60.3 11.3 15.0 143.6 11.7 13.0 18.4 38.7 8.6 0.2 20.3 8.4 76.6 33.6 18.3 26.8 27.8 5.5 138.5 26.8 8.8 49.6 37.6 0.9 2.1 10.6 5.5 13.0 22.5 97.0 5.7 52.0 4.3 15.3 4.4 0.4 13.1 61.7 31.1 0.9 1.0 24.1 43.3 9.9 10.0 205.8 28.5 19.7 PLAU "UPA, URK" ENSG00000122861 "Plasminogen activator, urokinase" P00749 10 73909177-73917496 "Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Fibrinolysis, Hemostasis, Plasminogen activation" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 103.8;urinary bladder: 128.5" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 635.9;Basal respiratory cells: 237.3;Pancreatic endocrine cells: 613.9;Prostatic glandular cells: 695.0;Urothelial cells: 869.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "myeloid DC: 1.1;neutrophil: 2.1;plasmacytoid DC: 2.0" "Group enriched" "Detected in many" 11 "dendritic cells: 2.0;granulocytes: 2.1" "Cell line enhanced" "Detected in many" "CAPAN-2: 856.0;LHCN-M2: 822.4;RPTEC TERT1: 3100.7;U-251 MG: 869.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA070796 Supported Uncertain "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 647000 88000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus, Vesicles" "HPA070796: " "unprognostic (1.96e-2)" "unprognostic (2.99e-2)" "unprognostic (7.40e-2)" "prognostic favorable (3.38e-4)" "unprognostic (4.73e-2)" "prognostic unfavorable (2.70e-4)" "unprognostic (1.39e-2)" "prognostic unfavorable (4.04e-4)" "unprognostic (2.26e-1)" "unprognostic (6.58e-2)" "prognostic unfavorable (1.32e-4)" "unprognostic (1.61e-1)" "prognostic unfavorable (3.51e-4)" "unprognostic (2.83e-1)" "unprognostic (3.37e-2)" "unprognostic (1.51e-2)" "unprognostic (1.77e-2)" 57.6 4.8 2.5 41.7 2.7 36.2 17.6 2.7 8.9 9.3 4.4 13.1 11.9 22.0 16.7 14.4 10.3 28.5 23.1 2.4 2.9 103.8 5.0 22.0 14.3 3.8 2.9 2.3 10.1 8.3 2.9 36.5 5.4 9.1 18.2 0.3 17.3 13.7 10.8 25.5 13.7 23.4 3.3 40.6 15.7 3.7 4.7 5.9 17.9 18.9 7.2 128.5 16.2 4.7 171.1 88.9 36.8 1.7 3.1 59.5 2.0 101.9 461.6 40.0 62.2 2.3 856.0 0.1 184.0 14.5 416.9 114.1 0.9 165.8 44.8 9.9 0.0 0.1 4.4 1.7 72.6 15.6 32.3 158.7 20.2 271.4 103.7 447.0 114.7 1.0 1.1 0.9 822.4 0.2 0.2 22.7 10.8 0.3 244.5 0.4 112.6 0.9 3100.7 130.6 0.1 0.2 0.3 4.0 2.4 25.4 1.2 22.9 300.6 3.5 20.3 21.6 869.8 0.2 1.3 1.6 216.0 25.5 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 2.1 0.0 0.0 2.0 0.0 0.1 2.5 2.7 2.7 8.9 2.4 2.9 3.8 2.9 5.4 3.3 4.7 4.7 29.0 3.2 4.6 0.3 1.4 37.3 635.9 237.3 19.9 0.0 3.0 24.4 2.5 0.0 103.6 29.5 0.0 28.0 1.6 0.6 68.4 62.7 0.5 50.7 22.2 46.4 3.5 0.0 0.2 21.3 21.7 69.7 0.0 68.9 31.1 0.1 3.9 0.0 39.8 0.0 0.3 0.1 140.4 4.0 33.1 1.3 2.5 53.4 7.2 4.7 23.8 0.0 0.0 0.5 0.2 613.9 0.3 0.0 0.5 695.0 0.0 1.4 35.4 0.0 6.6 27.6 65.2 0.0 0.2 60.6 29.5 17.5 4.7 0.6 1.7 869.6 PLCG2 ENSG00000197943 "Phospholipase C gamma 2" P16885 16 81739097-81962685 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 706.3;choroid plexus: 347.5" "Cell type enhanced" "Detected in many" "Adipocytes: 187.0;Bipolar cells: 224.8;Muller glia cells: 221.7;Rod photoreceptor cells: 196.2" "Cancer enhanced" "Detected in all" "renal cancer: 9.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 183.3;HMC-1: 84.2;REH: 75.1;U-698: 403.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004280, HPA020099, HPA020100" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 8200 "Cluster 5: Granulocytes - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Cytosol" Nucleoplasm "CAB004280: AB_628120, HPA020099: AB_1855324, HPA020100: AB_1855325" "unprognostic (2.86e-2)" "unprognostic (1.34e-1)" "unprognostic (1.09e-3)" "unprognostic (1.10e-1)" "unprognostic (1.58e-1)" "prognostic favorable (6.71e-4)" "unprognostic (6.23e-2)" "unprognostic (5.01e-2)" "unprognostic (2.22e-1)" "unprognostic (4.58e-2)" "unprognostic (4.66e-2)" "unprognostic (1.71e-2)" "prognostic favorable (4.88e-4)" "unprognostic (1.52e-2)" "unprognostic (1.21e-1)" "unprognostic (2.89e-1)" "unprognostic (3.40e-3)" 9.0 4.2 69.4 33.0 141.3 30.3 8.5 706.3 105.2 5.0 347.5 8.6 17.3 8.6 22.5 4.6 5.5 13.4 4.3 40.1 122.6 23.4 14.3 9.4 66.8 301.3 122.7 1.6 3.9 2.8 1.2 8.2 207.3 2.8 7.0 0.5 7.1 3.4 1.9 4.0 19.4 8.8 241.5 34.8 8.7 2.0 283.3 10.0 6.9 3.6 72.0 10.1 3.9 437.2 1.4 3.2 0.6 2.9 0.2 0.2 4.0 0.3 0.4 2.3 0.8 0.9 8.1 183.3 30.1 0.2 7.4 4.2 4.0 0.5 1.4 1.4 2.1 22.1 0.4 0.3 1.2 22.3 84.2 0.3 1.8 1.3 1.0 0.3 4.2 8.1 2.5 15.0 0.4 5.7 2.6 55.5 3.1 2.3 1.3 75.1 0.1 23.7 0.5 3.9 1.4 0.4 5.0 1.6 1.5 3.9 3.3 67.7 1.1 0.4 3.2 0.4 0.6 35.2 61.4 403.4 0.3 30.0 1.6 9.4 12.1 76.2 1.9 16.1 0.9 51.1 0.6 2.9 10.7 49.6 0.8 1.9 65.7 41.3 36.8 7.0 0.5 6.9 69.4 141.3 706.3 105.2 40.1 122.6 301.3 122.7 207.3 241.5 283.3 437.2 187.0 12.8 54.0 0.0 138.3 2.9 1.6 2.3 1.8 224.8 139.5 113.0 7.2 28.6 13.1 16.5 104.3 13.6 94.0 0.4 13.7 2.6 20.5 65.5 88.0 61.7 21.5 23.2 0.7 0.0 2.2 30.6 16.8 86.6 40.4 29.0 37.1 43.2 27.7 101.0 0.8 2.7 65.1 47.4 9.4 30.7 11.1 46.7 8.8 95.5 21.8 221.7 47.4 2.0 1.3 0.1 9.8 4.9 138.6 3.5 5.5 5.9 6.9 196.2 6.6 28.0 51.9 4.8 2.9 3.0 2.3 11.1 48.2 8.7 1.9 6.5 PLCH1 "DKFZp434C1372, KIAA1069, MGC117152, PLCeta1, PLCL3" ENSG00000114805 "Phospholipase C eta 1" Q4KWH8 3 155375580-155745071 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 16.6;retina: 12.4" "Group enriched" "Detected in many" 4 "Astrocytes: 93.7;Early spermatids: 206.2;Excitatory neurons: 126.0;Inhibitory neurons: 131.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 12.3;AF22: 39.0;HEL: 10.1;NTERA-2: 20.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036176, HPA057978" Uncertain Enhanced Vesicles NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA036176: AB_10671837, HPA057978: AB_2683569" "unprognostic (1.08e-2)" "unprognostic (3.68e-1)" "unprognostic (2.17e-2)" "unprognostic (1.55e-2)" "unprognostic (3.50e-4)" "unprognostic (6.41e-2)" "unprognostic (2.94e-5)" "unprognostic (5.04e-2)" "unprognostic (2.41e-1)" "unprognostic (2.24e-3)" "unprognostic (4.84e-2)" "unprognostic (1.76e-2)" "prognostic favorable (3.03e-5)" "unprognostic (3.28e-2)" "unprognostic (1.62e-1)" "unprognostic (1.47e-1)" "unprognostic (1.37e-2)" 0.0 0.0 5.5 0.3 4.8 0.2 2.6 4.5 6.0 1.2 9.3 2.5 2.5 0.7 8.2 0.1 8.1 1.5 1.8 3.8 1.4 1.2 0.1 4.0 0.0 1.3 4.6 0.1 1.4 0.4 1.5 0.4 1.5 0.3 2.4 12.4 1.3 1.9 0.2 0.1 2.5 0.1 1.6 0.0 3.8 11.3 1.3 16.6 5.7 0.0 0.0 0.4 0.1 2.0 0.0 12.3 39.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.2 2.4 9.8 0.0 0.8 0.0 0.1 0.0 7.0 0.0 0.0 0.0 3.6 10.1 0.0 1.4 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.2 0.3 0.0 0.0 4.4 2.4 9.4 20.8 1.3 1.6 0.9 0.0 0.0 2.4 0.2 3.6 0.9 0.0 9.4 0.0 5.7 4.2 0.0 0.0 0.0 0.2 0.0 1.7 0.4 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.5 4.8 4.5 6.0 3.8 1.4 1.3 4.6 1.5 1.6 1.3 2.0 0.0 3.2 13.6 93.7 0.3 0.0 0.4 0.5 0.6 10.5 4.0 5.0 0.8 4.3 2.3 1.8 4.2 0.0 0.1 2.7 0.0 2.2 206.2 34.6 1.3 0.6 3.0 0.0 126.0 2.3 0.3 0.3 15.3 13.6 0.0 0.1 0.0 0.0 0.2 25.2 131.5 4.0 0.0 0.3 0.4 21.4 1.2 0.4 0.0 12.2 0.1 16.1 0.0 5.5 5.7 1.5 4.6 0.4 0.0 0.4 2.8 2.1 23.4 3.0 0.0 0.0 0.2 2.4 1.2 0.7 0.1 0.0 0.3 0.1 4.4 0.4 PLD1 ENSG00000075651 "Phospholipase D1" Q13393 3 171600404-171810950 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 86.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 519.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 57.5;SK-MEL-30: 31.1;TIME: 50.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004527, HPA042396, HPA066938" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Nucleoplasm "CAB004527: AB_677324, HPA042396: AB_2677977, HPA066938: " "unprognostic (3.23e-1)" "unprognostic (3.27e-1)" "unprognostic (5.82e-2)" "unprognostic (5.13e-2)" "unprognostic (4.58e-1)" "unprognostic (4.76e-2)" "unprognostic (9.03e-2)" "unprognostic (1.46e-1)" "unprognostic (6.23e-2)" "unprognostic (8.02e-2)" "unprognostic (2.06e-2)" "unprognostic (2.95e-2)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.76e-6)" 7.8 26.4 9.2 6.6 24.7 7.8 7.5 18.4 13.6 10.4 4.5 14.6 46.9 6.2 2.8 33.0 6.4 86.8 24.4 10.5 14.3 12.0 33.7 4.7 9.1 24.8 22.0 24.2 21.2 1.6 2.3 10.7 23.5 3.4 14.7 0.5 13.8 6.0 2.5 29.2 43.9 4.8 14.7 15.7 8.2 5.0 19.0 4.1 3.7 6.8 10.8 5.1 12.4 41.4 4.5 7.2 3.7 1.4 11.2 12.6 7.7 2.3 9.9 3.5 4.3 1.1 6.4 0.0 17.0 0.9 24.0 15.2 0.6 2.0 5.7 3.6 3.2 4.2 11.5 26.1 4.9 7.3 18.9 4.9 10.9 4.2 2.0 10.0 57.5 1.2 2.8 0.0 0.9 1.3 0.0 6.4 0.8 11.9 5.1 0.2 1.5 0.1 8.9 1.8 0.1 0.1 7.9 4.7 31.1 5.1 9.0 9.7 50.7 1.5 5.7 4.0 2.5 9.6 8.2 0.1 6.7 8.6 1.9 8.3 1.8 2.3 0.3 1.1 2.6 0.0 0.2 0.6 0.6 0.0 0.0 0.1 1.0 2.2 0.4 0.0 0.8 0.6 9.2 24.7 18.4 13.6 10.5 14.3 24.8 22.0 23.5 14.7 19.0 41.4 7.7 0.0 4.7 2.0 0.9 7.1 3.4 11.0 10.8 0.4 4.9 5.6 33.6 57.2 11.1 1.8 0.0 3.0 1.9 37.5 3.9 8.4 13.1 1.0 4.8 7.4 4.2 6.3 8.9 3.4 3.7 15.7 27.0 1.3 27.9 10.4 6.4 15.9 20.0 0.0 12.1 23.6 6.1 13.2 2.4 9.5 10.5 10.2 12.4 98.4 5.4 0.0 1.0 12.5 519.6 2.4 18.3 4.5 3.4 0.7 38.3 48.0 9.9 0.1 19.7 3.8 8.4 6.1 5.3 93.5 34.9 2.3 2.3 12.1 17.8 4.7 PLD5 FLJ40773 ENSG00000180287 "Phospholipase D family member 5" Q8N7P1 1 242082986-242524697 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 16.2;choroid plexus: 52.8" "Group enriched" "Detected in some" 6 "Inhibitory neurons: 319.5;Oligodendrocyte precursor cells: 127.6;Oligodendrocytes: 226.8" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Region enriched" "Detected in all" 5 "cerebellum: 16.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 3.0;AF22: 10.3;HDLM-2: 5.3;SH-SY5Y: 2.9;U-2 OS: 3.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028389, HPA050367" Approved Vesicles,Mitochondria,Cytosol No No "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "Vesicles, Cytosol" "HPA028389: AB_10602145, HPA050367: AB_2681105" "unprognostic (5.20e-2)" "unprognostic (1.05e-1)" "unprognostic (9.14e-2)" "unprognostic (1.25e-1)" "unprognostic (2.27e-2)" "unprognostic (1.32e-2)" "unprognostic (8.77e-2)" "unprognostic (4.36e-1)" "unprognostic (1.95e-1)" "unprognostic (2.08e-3)" "unprognostic (2.71e-1)" "unprognostic (2.16e-5)" "unprognostic (2.79e-2)" "unprognostic (4.46e-1)" "unprognostic (3.44e-3)" "unprognostic (2.18e-1)" 0.4 1.7 1.7 0.0 2.9 0.0 0.4 16.2 2.5 0.6 52.8 0.2 0.0 1.1 0.2 0.4 1.1 0.1 0.1 3.4 2.5 0.4 0.0 0.2 1.1 2.9 2.6 2.1 1.0 0.2 2.4 0.4 2.8 0.8 0.1 0.3 0.7 3.0 0.2 0.1 0.1 0.9 2.0 0.7 0.3 1.5 2.2 0.4 0.2 0.0 0.4 0.1 0.3 2.7 0.0 3.0 10.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.4 0.0 5.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.2 0.0 0.0 0.0 0.0 0.3 2.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 2.9 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.9 16.2 2.5 3.4 2.5 2.9 2.6 2.8 2.0 2.2 2.7 0.1 0.0 0.0 7.8 0.2 0.1 0.0 0.0 1.2 0.5 0.0 1.7 1.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 9.1 2.9 0.6 0.3 0.0 0.0 35.5 0.0 0.0 3.1 0.0 8.2 0.0 0.7 0.0 0.0 0.0 3.3 319.5 0.2 0.0 0.0 0.0 21.0 5.0 0.1 0.0 5.6 0.0 0.4 0.0 127.6 226.8 0.0 0.0 2.2 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 1.5 1.2 0.6 0.2 0.1 0.3 0.0 0.0 0.0 0.1 PLEK2 ENSG00000100558 "Pleckstrin 2" Q9NYT0 14 67386984-67412167 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 51.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 149.0;Pancreatic endocrine cells: 179.8;Suprabasal keratinocytes: 90.6;Theca cells: 107.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "memory CD4 T-cell: 2.0;naive CD4 T-cell: 3.1" "Lineage enriched" "Detected in single" 7 "T-cells: 3.1" "Cell line enhanced" "Detected in many" "A-431: 91.0;CAPAN-2: 94.4;HBEC3-KT: 177.4;PC-3: 64.1;TIME: 69.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001208 Enhanced Uncertain Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles Cytosol "HPA001208: AB_1079631" "unprognostic (4.41e-3)" "unprognostic (3.77e-1)" "unprognostic (1.15e-1)" "unprognostic (6.23e-2)" "unprognostic (6.88e-2)" "unprognostic (3.17e-3)" "unprognostic (1.18e-2)" "prognostic unfavorable (1.58e-4)" "unprognostic (1.97e-1)" "unprognostic (9.21e-3)" "prognostic unfavorable (8.26e-5)" "unprognostic (1.06e-1)" "unprognostic (3.09e-3)" "unprognostic (2.90e-1)" "unprognostic (1.29e-1)" "unprognostic (8.98e-2)" "unprognostic (4.59e-2)" 0.8 51.1 0.3 5.5 0.3 12.7 3.9 0.8 0.6 3.9 0.1 25.1 29.6 1.5 32.4 16.4 1.7 3.9 0.3 0.4 0.2 9.7 29.7 1.6 0.2 0.3 0.2 0.6 7.9 7.0 1.3 1.5 0.3 7.7 28.7 0.1 6.8 4.2 0.3 26.5 32.6 1.3 0.2 0.6 20.6 3.1 0.4 22.9 23.5 0.2 5.5 12.1 7.9 0.4 91.0 13.4 0.0 0.1 0.0 1.0 8.4 17.9 2.7 4.2 5.2 48.8 94.4 0.0 17.3 2.5 0.2 42.4 0.1 177.4 9.6 0.1 0.7 0.0 19.4 0.4 3.8 0.0 0.0 1.9 12.3 4.6 55.4 0.0 14.8 0.0 0.4 0.4 3.0 28.9 0.0 0.2 0.3 57.4 64.1 0.0 0.1 14.0 30.0 2.4 0.7 0.2 17.0 7.9 5.2 0.9 11.6 0.9 69.3 0.0 54.1 0.3 0.4 0.3 0.2 0.3 10.7 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.0 0.3 0.4 0.0 3.1 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.3 0.8 0.6 0.4 0.2 0.3 0.2 0.3 0.2 0.4 0.4 0.1 0.0 1.1 1.0 0.6 149.0 29.0 69.9 37.0 0.0 4.9 6.0 0.5 10.0 11.8 5.5 0.0 1.0 0.0 25.0 3.9 42.1 0.1 2.3 0.2 2.0 8.4 16.0 0.8 46.3 5.5 4.2 37.2 2.2 0.0 24.0 0.0 11.5 6.8 0.0 0.6 68.5 26.4 1.3 57.1 0.3 0.3 7.4 21.4 0.0 5.2 0.0 0.0 0.5 0.3 179.8 23.9 0.0 0.0 15.8 47.9 3.2 4.5 0.0 0.0 0.0 4.6 0.4 2.3 21.2 90.6 1.5 1.3 107.7 54.8 25.5 PLEKHA6 "KIAA0969, PEPP3" ENSG00000143850 "Pleckstrin homology domain containing A6" Q9Y2H5 1 204218853-204377665 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 111.0;Distal enterocytes: 66.6;Excitatory neurons: 102.6;Inhibitory neurons: 62.5;Oligodendrocyte precursor cells: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 60.3;BEWO: 94.6;CAPAN-2: 79.2;OE19: 80.9;RT4: 66.4;SK-BR-3: 58.4;T-47d: 55.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028152, HPA028157, HPA054311" Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 45: Intestine - Brush border" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" Vesicles "HPA028152: AB_10601048, HPA028157: , HPA054311: AB_2682446" "unprognostic (9.81e-3)" "unprognostic (3.05e-1)" "unprognostic (1.59e-2)" "unprognostic (3.14e-2)" "unprognostic (1.63e-1)" "unprognostic (1.30e-1)" "unprognostic (2.37e-2)" "unprognostic (1.38e-2)" "unprognostic (9.01e-2)" "unprognostic (3.32e-1)" "unprognostic (9.60e-3)" "unprognostic (1.53e-1)" "unprognostic (5.02e-3)" "unprognostic (1.23e-1)" "unprognostic (8.22e-2)" "unprognostic (5.17e-2)" "prognostic favorable (3.57e-4)" 5.1 6.6 20.4 6.0 21.6 0.4 13.7 20.9 34.4 4.1 9.1 32.2 25.5 4.8 12.9 17.2 9.3 13.2 20.8 19.6 18.7 27.4 27.5 3.2 0.6 23.1 24.3 4.6 10.2 5.7 31.1 8.8 23.3 13.8 29.3 11.4 9.0 13.9 6.0 4.0 29.5 3.8 17.9 3.1 39.7 5.4 34.6 1.0 4.0 2.4 2.4 12.7 7.5 24.1 60.3 36.8 23.7 0.1 0.3 0.6 94.6 2.1 6.6 0.2 0.3 17.8 79.2 0.3 17.3 1.4 0.3 6.7 0.3 6.5 0.3 0.2 3.8 0.2 15.2 25.7 3.5 0.0 0.1 1.0 19.6 0.0 5.0 7.2 10.4 0.8 0.1 0.2 23.9 26.7 0.1 0.1 7.4 80.9 44.6 0.0 0.2 0.1 23.0 66.4 4.8 48.4 26.6 58.4 0.4 4.9 55.3 0.3 0.7 0.0 1.0 0.3 0.5 0.2 0.0 0.1 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 21.6 20.9 34.4 19.6 18.7 23.1 24.3 23.3 17.9 34.6 24.1 0.2 0.0 10.9 111.0 0.3 0.1 4.2 1.9 0.6 41.6 15.7 8.1 16.6 37.1 4.5 9.2 20.9 6.6 0.5 66.6 3.9 8.4 10.4 4.0 1.3 1.2 16.8 2.7 102.6 5.1 2.4 9.0 40.8 6.2 0.0 0.3 5.0 21.4 0.8 18.5 62.5 32.7 4.1 0.6 0.7 4.0 5.3 0.7 0.0 15.0 0.1 1.2 0.0 85.5 41.8 13.3 33.2 3.8 0.1 6.9 15.2 11.7 7.2 7.1 0.0 26.4 1.1 0.6 0.2 1.4 0.6 21.6 0.6 0.1 34.5 13.7 PLEKHM1 KIAA0356 ENSG00000225190 "Pleckstrin homology and RUN domain containing M1" Q9Y4G2 17 45435900-45490749 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 31.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.5" "Cell line enhanced" "Detected in many" "OE19: 26.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025018, HPA039473" Approved Supported Nucleoli,Vesicles NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" Vesicles Nucleoli "HPA025018: AB_1855465, HPA039473: AB_2676526" "unprognostic (1.52e-1)" "unprognostic (3.13e-2)" "unprognostic (4.29e-2)" "prognostic favorable (1.28e-6)" "unprognostic (8.71e-2)" "unprognostic (3.06e-2)" "prognostic unfavorable (3.25e-4)" "unprognostic (2.20e-2)" "unprognostic (1.88e-1)" "unprognostic (2.93e-2)" "unprognostic (4.02e-1)" "unprognostic (3.93e-2)" "unprognostic (4.31e-2)" "unprognostic (2.27e-1)" "unprognostic (1.60e-1)" "unprognostic (1.05e-1)" "unprognostic (1.76e-1)" 7.0 6.4 2.9 5.5 2.9 9.7 6.2 3.5 3.8 12.9 3.2 6.5 3.5 5.7 1.0 31.7 5.9 5.3 6.2 2.8 3.1 3.6 3.6 8.8 4.8 3.7 3.1 4.9 6.1 4.4 5.7 2.9 3.2 5.1 3.6 1.6 14.4 0.9 12.3 11.8 6.2 2.0 2.8 6.8 5.6 3.4 3.4 5.4 6.5 7.2 4.8 6.8 13.6 3.7 7.3 11.0 1.7 5.4 8.4 4.8 0.1 3.3 4.9 1.9 2.6 4.2 6.0 5.2 3.4 3.9 14.1 1.7 4.1 1.9 1.6 13.7 3.5 0.0 5.6 6.9 2.0 0.0 4.3 2.2 4.9 0.9 8.0 3.8 10.0 0.0 5.2 6.2 9.1 6.0 5.2 1.1 1.7 26.6 9.0 2.8 5.6 5.3 6.0 16.8 3.2 2.1 3.2 4.5 5.2 4.8 10.1 5.3 19.1 12.7 3.6 5.2 5.9 0.6 6.2 1.8 7.7 2.8 5.8 2.8 1.2 1.0 0.2 0.3 0.0 1.2 0.6 0.2 0.3 0.3 0.2 0.0 6.5 0.7 0.4 0.2 0.5 0.2 2.9 2.9 3.5 3.8 2.8 3.1 3.7 3.1 3.2 2.8 3.4 3.7 12.6 12.8 18.1 7.8 17.5 18.0 18.1 10.3 6.8 10.4 11.7 8.4 8.7 15.7 12.7 12.9 16.7 4.8 24.3 25.6 5.9 8.1 4.3 24.9 11.1 12.1 13.8 10.8 13.5 8.2 4.7 12.1 19.9 27.9 1.3 5.4 12.8 8.1 9.1 16.8 13.3 13.0 4.1 27.9 15.2 2.0 7.2 21.1 7.2 9.4 13.7 7.3 14.4 7.5 20.8 18.3 17.7 7.9 22.9 27.2 8.6 10.5 11.9 8.2 0.0 17.7 7.6 7.6 3.7 10.0 16.3 8.6 18.5 9.3 12.2 43.1 PLEKHM3 "DAPR, PLEKHM1L" ENSG00000178385 "Pleckstrin homology domain containing M3" Q6ZWE6 2 207821288-208025527 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 99.1;Inhibitory neurons: 70.5;Microglial cells: 36.5;Oligodendrocyte precursor cells: 45.2;Oligodendrocytes: 86.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035046 Uncertain Approved Vesicles,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 23: Testis - Cell cycle regulation" "Cluster 28: BEWO - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol Vesicles "HPA035046: AB_10603128" "unprognostic (3.62e-1)" "unprognostic (1.58e-2)" "unprognostic (8.27e-2)" "unprognostic (3.18e-2)" "unprognostic (5.66e-2)" "unprognostic (4.77e-2)" "unprognostic (6.06e-2)" "unprognostic (8.20e-2)" "unprognostic (4.13e-2)" "unprognostic (2.92e-3)" "unprognostic (2.17e-1)" "unprognostic (1.09e-1)" "unprognostic (4.86e-4)" "unprognostic (2.42e-1)" "unprognostic (3.12e-1)" "unprognostic (5.72e-2)" "unprognostic (1.33e-2)" 2.9 4.1 2.3 1.3 2.6 4.3 2.4 0.4 2.9 2.7 0.0 3.1 0.9 2.5 0.9 1.6 2.0 1.4 2.9 2.8 2.1 1.9 3.1 2.9 1.5 2.0 2.6 3.1 2.2 4.0 2.5 1.4 2.2 2.5 1.5 8.3 2.2 1.4 2.4 2.6 1.9 1.9 0.2 1.9 2.2 1.7 1.3 2.2 3.6 1.6 1.4 1.9 2.5 2.0 0.7 0.7 1.6 0.9 2.7 2.7 2.5 1.5 1.6 1.2 1.1 0.9 0.7 0.6 1.5 1.8 1.2 0.8 1.7 2.2 1.6 1.2 2.6 1.3 2.2 1.3 1.6 1.4 0.7 2.2 2.6 1.3 1.6 1.9 1.3 2.1 0.8 1.7 1.5 0.4 1.7 0.9 1.6 0.5 0.8 1.3 1.4 1.3 0.6 0.9 3.5 1.8 1.4 0.1 1.5 2.7 0.4 1.1 1.8 1.9 1.1 1.1 1.0 2.0 2.4 0.6 2.2 0.8 1.4 1.3 0.8 0.4 0.9 0.3 0.3 0.9 0.8 0.8 0.7 0.6 1.0 0.8 2.6 0.9 0.7 0.7 0.5 0.2 2.3 2.6 0.4 2.9 2.8 2.1 2.0 2.6 2.2 0.2 1.3 2.0 6.3 19.2 21.7 29.0 2.7 0.0 0.2 0.1 0.6 3.1 4.1 3.7 1.2 1.5 5.6 1.8 12.5 0.3 4.1 1.2 0.0 3.1 2.5 4.1 6.3 2.3 0.0 4.0 99.1 3.4 0.5 3.0 2.0 4.7 0.0 25.0 0.4 0.6 0.6 6.7 70.5 0.1 0.0 1.0 2.4 5.2 0.3 3.8 0.0 36.5 4.6 2.3 0.0 45.2 86.9 3.5 1.6 0.0 2.0 0.2 1.1 4.9 0.8 9.6 0.0 1.7 3.8 0.4 0.7 1.1 0.1 0.1 2.5 6.9 0.5 0.1 PLEKHS1 "bA211N11.2, C10orf81, FLJ23537" ENSG00000148735 "Pleckstrin homology domain containing S1" Q5SXH7 10 113751262-113783429 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 30.5;cervix: 63.6;intestine: 43.9;pancreas: 36.9;salivary gland: 57.0" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 35.1;Club cells: 70.7;Endometrial ciliated cells: 33.8;Exocrine glandular cells: 31.1;Ionocytes: 38.7;Proximal enterocytes: 42.1;Respiratory ciliated cells: 157.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 10.1;OE19: 53.5;RT4: 22.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA037583 Approved Vesicles,Centrosome NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Centrosome Vesicles "HPA037583: AB_10671762" "unprognostic (2.64e-1)" "unprognostic (1.64e-2)" "unprognostic (2.74e-2)" "unprognostic (3.60e-2)" "unprognostic (1.07e-1)" "unprognostic (2.63e-2)" "unprognostic (1.74e-2)" "unprognostic (2.36e-2)" "unprognostic (8.43e-2)" "unprognostic (6.82e-2)" "unprognostic (2.57e-1)" "unprognostic (1.21e-2)" "unprognostic (0.00e+0)" "unprognostic (4.00e-3)" "unprognostic (2.19e-1)" "unprognostic (2.27e-1)" "prognostic favorable (1.03e-4)" 0.3 0.1 0.0 7.3 0.0 0.3 30.5 0.0 0.3 63.6 0.0 3.6 43.9 1.8 3.9 1.0 9.4 2.7 0.4 0.0 0.0 0.9 0.1 6.7 0.2 0.2 0.0 0.1 36.9 0.1 0.2 0.1 0.0 6.0 4.7 0.4 57.0 3.3 0.0 0.8 38.7 0.5 0.0 0.2 8.8 0.9 0.0 0.1 0.1 0.0 2.8 1.5 0.0 0.1 0.2 1.4 0.0 0.2 0.0 0.0 0.3 0.2 0.2 0.1 0.7 0.2 10.1 0.2 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.2 0.0 53.5 0.0 0.2 6.4 0.3 1.7 22.3 0.1 0.2 0.1 1.4 0.0 0.0 6.3 0.0 0.0 0.2 0.2 0.2 0.5 4.7 0.2 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 3.2 3.2 0.3 0.0 0.1 0.3 35.1 0.0 0.0 16.6 8.3 0.4 0.0 70.7 0.0 0.0 0.0 0.1 6.7 0.0 4.9 13.2 33.8 0.3 0.5 0.0 0.0 0.2 31.1 0.0 0.6 3.1 1.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 5.6 38.7 0.0 0.0 5.3 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 1.2 2.8 0.4 0.0 1.4 42.1 0.3 157.3 0.0 0.0 0.3 3.7 0.2 0.1 0.6 0.0 0.0 0.3 0.0 12.1 0.5 PLIN5 "LSDA5, LSDP5, MLDP, OXPAT" ENSG00000214456 "Perilipin 5" Q00G26 19 4522531-4535224 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 202.0;skeletal muscle: 149.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 47.1;Astrocytes: 53.8;Cardiomyocytes: 39.8;Hepatic stellate cells: 42.1;Hepatocytes: 140.5" "Cancer enhanced" "Detected in many" "liver cancer: 9.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.9" "Lineage enriched" "Detected in single" 20 "granulocytes: 13.9" "Cell line enhanced" "Detected in some" "AN3-CA: 2.3;BEWO: 3.2;RT4: 3.1;SH-SY5Y: 2.8;T-47d: 6.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA077050 Supported "Vesicles,Lipid droplets" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 6: T47d - Mammary gland" "Cluster 15: Hepatocytes - Hemostasis" "Vesicles, Lipid droplets" "HPA077050: " "prognostic favorable (7.68e-4)" "unprognostic (1.01e-1)" "unprognostic (4.22e-2)" "prognostic unfavorable (8.56e-4)" "unprognostic (1.24e-2)" "unprognostic (6.06e-3)" "prognostic favorable (2.81e-4)" "unprognostic (1.11e-2)" "unprognostic (4.67e-2)" "unprognostic (1.05e-1)" "unprognostic (1.63e-1)" "unprognostic (1.54e-1)" "prognostic favorable (1.97e-4)" "unprognostic (3.18e-1)" "unprognostic (1.40e-1)" "unprognostic (8.28e-3)" "prognostic favorable (2.16e-4)" 41.9 6.4 10.8 3.5 11.2 5.2 29.3 6.9 9.6 7.5 12.8 5.4 1.5 2.7 3.9 3.4 12.6 2.0 62.7 8.5 8.1 30.1 202.0 9.3 0.5 8.4 9.2 90.8 112.2 1.5 18.9 0.2 6.9 17.6 0.6 0.9 61.0 3.9 149.2 8.0 5.3 0.5 6.8 8.2 58.9 3.3 9.4 0.4 9.8 24.7 1.0 11.2 2.7 6.4 0.2 0.1 0.5 2.3 1.7 0.1 3.2 0.1 0.1 0.1 0.0 0.2 0.5 0.1 0.7 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.1 0.1 0.8 1.1 0.4 0.3 0.4 0.4 0.0 0.0 0.0 0.2 0.2 0.1 0.7 0.2 0.1 0.6 0.1 0.4 0.4 0.3 0.3 0.1 0.1 2.1 0.2 3.1 0.3 2.8 0.2 0.4 0.0 0.2 6.3 0.4 0.3 0.3 0.3 0.2 0.2 0.3 0.1 0.1 0.2 0.6 0.1 1.9 0.4 0.8 0.3 0.3 0.2 0.3 0.2 0.2 0.1 0.4 0.3 0.3 13.9 0.6 0.3 0.3 0.1 0.1 10.8 11.2 6.9 9.6 8.5 8.1 8.4 9.2 6.9 6.8 9.4 6.4 6.0 9.6 47.1 53.8 1.6 0.5 18.4 2.3 4.0 1.2 9.2 1.9 39.8 35.8 11.5 1.8 0.0 0.4 0.1 11.9 9.8 8.7 1.5 20.8 1.4 7.4 0.0 2.7 1.1 12.3 0.5 1.3 16.3 5.1 3.8 18.7 42.1 140.5 0.5 0.0 1.8 6.9 4.1 6.9 0.5 0.3 0.3 2.5 0.0 5.6 0.1 8.1 0.0 11.1 2.0 4.8 1.3 2.6 0.5 6.6 0.5 11.1 10.4 1.2 13.1 25.8 1.8 6.2 6.6 0.5 1.0 1.4 1.1 20.5 8.8 11.5 PLOD1 "LH1, LLH, PLOD" ENSG00000083444 "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1" Q02809 1 11934205-11975538 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 236.8;Sertoli cells: 105.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049137, HPA055799" Uncertain Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 3600000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles Nucleoplasm "HPA049137: AB_2680649, HPA055799: AB_2682924" "unprognostic (1.00e-1)" "unprognostic (2.69e-3)" "unprognostic (9.21e-3)" "unprognostic (5.43e-2)" "unprognostic (7.53e-3)" "unprognostic (1.12e-2)" "prognostic unfavorable (2.79e-4)" "unprognostic (1.13e-3)" "unprognostic (1.23e-1)" "unprognostic (1.79e-1)" "unprognostic (4.15e-3)" "unprognostic (2.32e-1)" "prognostic unfavorable (1.91e-12)" "unprognostic (2.79e-1)" "unprognostic (7.12e-2)" "unprognostic (5.92e-2)" "prognostic unfavorable (2.43e-4)" 58.1 34.6 46.3 35.2 51.2 16.1 41.2 48.6 56.6 65.4 46.4 47.3 37.7 65.0 30.5 21.3 51.1 42.0 71.2 44.5 47.4 45.5 78.1 44.4 15.4 49.6 50.8 54.4 39.0 36.9 29.6 83.8 52.4 34.7 23.2 10.6 75.9 40.6 40.5 27.2 35.6 78.4 44.8 31.5 35.5 11.6 52.2 7.9 34.9 41.6 12.9 42.4 36.0 53.1 112.5 91.4 51.3 239.7 343.4 190.6 39.0 330.4 436.1 170.4 287.1 105.2 71.5 63.1 339.5 367.3 125.9 93.4 75.6 115.6 115.6 66.2 78.3 34.0 136.6 137.3 212.5 21.9 162.7 234.0 59.7 206.2 81.9 573.3 305.0 14.8 97.6 30.9 180.2 71.1 5.7 58.6 22.9 115.4 131.6 25.8 100.0 141.0 98.7 24.3 19.2 77.7 137.3 97.4 164.8 80.4 48.3 55.9 298.7 190.1 141.6 236.3 161.9 71.4 123.7 38.7 425.1 75.5 316.8 0.0 40.3 2.0 17.3 34.4 3.1 1.7 3.0 8.4 32.7 3.4 1.2 6.4 35.5 5.4 32.3 4.9 2.0 22.6 46.3 51.2 48.6 56.6 44.5 47.4 49.6 50.8 52.4 44.8 52.2 53.1 19.4 0.0 7.9 9.4 3.7 7.0 8.0 22.8 8.0 5.7 17.9 17.5 18.3 8.6 8.6 11.0 2.1 39.7 8.7 14.8 3.9 30.3 1.0 11.0 62.2 33.9 8.4 3.0 4.2 9.8 236.8 47.5 17.3 24.8 0.0 20.4 36.8 37.1 46.3 6.7 5.8 12.5 4.1 26.5 8.3 2.4 44.4 16.3 10.6 15.9 17.9 7.9 15.5 3.0 9.8 22.4 15.4 24.5 19.4 8.0 41.5 16.7 4.5 3.1 105.2 77.2 47.3 0.5 3.3 7.4 5.1 33.7 5.5 37.1 16.6 3.9 PLPP5 "DPPL1, HTPAP, PPAPDC1B" ENSG00000147535 "Phospholipid phosphatase 5" Q8NEB5 8 38263130-38269243 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 264.5;Prostatic glandular cells: 146.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 80.2;memory B-cell: 211.8;naive B-cell: 305.9" "Group enriched" "Detected in all" 7 "B-cells: 305.9;granulocytes: 80.2" "Cell line enhanced" "Detected in all" "RPMI-8226: 140.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055777 Approved Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA055777: AB_2682915" "unprognostic (4.54e-2)" "unprognostic (2.51e-3)" "unprognostic (3.66e-2)" "prognostic favorable (1.48e-5)" "unprognostic (1.80e-2)" "unprognostic (1.27e-2)" "unprognostic (5.58e-2)" "prognostic favorable (8.72e-5)" "unprognostic (9.79e-2)" "prognostic favorable (2.42e-5)" "unprognostic (1.50e-1)" "unprognostic (5.08e-2)" "prognostic unfavorable (8.33e-10)" "unprognostic (3.82e-2)" "unprognostic (1.58e-1)" "unprognostic (1.59e-3)" "unprognostic (1.57e-2)" 12.6 18.6 12.5 21.5 13.0 16.6 24.4 15.8 16.1 29.4 36.5 30.2 41.6 16.1 81.7 13.9 28.3 27.9 8.6 12.6 14.4 27.6 33.0 16.0 28.1 12.7 13.5 18.6 114.5 13.7 52.4 14.0 12.4 74.5 35.5 8.5 85.7 30.5 4.8 10.7 40.3 11.4 11.5 28.0 46.1 7.8 13.5 10.2 29.2 3.0 32.3 21.2 14.1 13.0 15.1 29.7 17.4 35.7 33.2 32.1 23.9 42.1 52.7 21.0 27.3 13.8 22.7 1.0 35.1 43.8 30.5 16.5 14.5 30.9 18.2 9.6 9.3 26.6 13.1 40.5 56.3 7.8 30.8 25.3 31.5 29.4 38.3 37.2 34.7 34.9 1.3 67.2 25.9 31.2 17.7 13.0 26.5 61.2 10.0 19.1 12.8 140.0 53.3 19.4 13.6 20.8 17.3 26.5 25.4 15.4 56.9 15.0 21.2 14.8 13.1 25.2 11.3 41.5 29.4 4.5 41.0 20.5 26.1 80.2 12.9 23.4 13.4 13.7 23.0 211.8 17.8 17.7 12.2 305.9 8.8 8.5 8.0 22.4 19.7 26.0 18.0 17.0 12.5 13.0 15.8 16.1 12.6 14.4 12.7 13.5 12.4 11.5 13.5 13.0 22.2 9.6 46.2 0.0 110.8 0.0 81.8 0.0 25.6 5.9 49.4 42.3 0.0 32.9 21.7 75.4 16.7 45.1 14.8 12.4 43.0 68.0 30.6 70.3 27.3 27.9 44.9 9.9 0.0 89.9 43.5 41.5 50.4 54.8 31.5 38.1 17.5 23.4 36.5 62.2 0.0 62.6 0.0 10.1 0.0 8.9 17.7 23.0 0.0 0.0 12.0 37.4 18.6 0.0 0.0 57.2 31.1 9.4 264.5 146.3 74.3 24.9 55.4 3.6 13.1 22.8 18.9 31.4 12.3 20.8 0.0 88.1 25.2 18.5 44.1 59.1 PLPP6 "FLJ46512, FLJ90191, PDP1, PPAPDC2" ENSG00000205808 "Phospholipid phosphatase 6" Q8IY26 9 4662294-4665258 "Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 82.2;Late spermatids: 46.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 5 "HDLM-2: 99.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018096 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 29: Non-specific - Vesicular transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" Cytosol "HPA018096: AB_1855609" "unprognostic (2.55e-2)" "unprognostic (8.29e-2)" "unprognostic (1.03e-1)" "unprognostic (4.36e-3)" "unprognostic (1.17e-1)" "unprognostic (4.38e-2)" "unprognostic (6.95e-3)" "unprognostic (1.33e-1)" "unprognostic (5.26e-2)" "unprognostic (9.06e-2)" "unprognostic (2.20e-2)" "unprognostic (1.45e-1)" "prognostic favorable (3.99e-4)" "unprognostic (2.56e-1)" "unprognostic (2.28e-2)" "unprognostic (2.87e-2)" "unprognostic (5.88e-2)" 3.6 6.6 3.8 6.2 4.0 1.5 7.3 7.0 5.0 5.0 8.7 9.3 10.5 4.0 12.7 7.4 3.3 4.6 2.8 4.3 3.3 5.4 18.9 3.4 8.2 3.4 3.6 4.0 17.2 7.7 4.7 7.1 3.6 16.4 9.9 5.1 7.7 4.8 1.9 8.2 11.4 3.4 3.3 6.0 11.3 5.9 3.3 6.1 7.1 1.5 8.4 5.2 5.1 3.5 8.2 8.3 8.8 10.9 6.9 7.7 8.8 5.5 7.1 4.4 5.0 2.2 5.3 7.9 2.2 5.5 10.9 10.0 6.2 7.8 4.6 99.2 5.9 15.7 8.7 11.3 6.3 5.7 11.4 8.5 6.2 3.4 7.5 5.8 6.6 8.8 2.7 8.1 5.6 8.8 5.4 15.0 8.1 8.2 2.9 5.3 0.0 6.1 7.6 9.3 22.0 11.1 6.5 5.8 3.5 10.8 8.2 12.7 7.8 3.9 3.3 5.3 3.6 1.7 6.4 2.0 6.1 4.1 3.7 6.8 4.1 3.5 3.1 3.7 3.6 2.6 5.6 4.8 4.2 3.3 9.6 6.9 1.8 4.2 4.4 3.2 8.6 4.1 3.8 4.0 7.0 5.0 4.3 3.3 3.4 3.6 3.6 3.3 3.3 3.5 2.8 6.4 2.7 0.0 2.6 0.0 2.5 0.0 2.8 7.5 4.2 2.7 0.0 5.7 1.3 1.8 2.1 18.6 2.9 9.7 1.9 11.0 82.2 2.1 3.4 3.0 10.9 2.1 0.0 13.9 2.9 2.3 7.1 5.3 0.0 4.1 4.2 15.3 6.5 3.3 0.0 7.3 0.0 4.7 0.0 46.3 2.8 1.7 0.0 0.0 3.0 4.6 3.1 0.0 0.0 10.8 6.5 4.9 1.5 7.5 13.4 2.8 0.0 4.9 0.0 1.7 1.8 0.5 1.1 4.6 0.0 10.4 3.4 3.5 5.1 3.1 PLPP7 "C9orf67, FLJ14662, MGC12921, NET39, PPAPDC3" ENSG00000160539 "Phospholipid phosphatase 7 (inactive)" Q8NBV4 9 131289459-131359022 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "heart muscle: 91.2;skeletal muscle: 210.1;tongue: 74.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 18.8;Horizontal cells: 8.4;Leydig cells: 5.0;Skeletal myocytes: 7.0" "Cancer enhanced" "Detected in many" "glioma: 5.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AN3-CA: 11.1;ASC diff: 11.4;ASC TERT1: 8.6;SCLC-21H: 11.3;SH-SY5Y: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070252 Uncertain Approved Nucleoplasm,Vesicles No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 37: Myocytes - Muscle contraction" Vesicles Nucleoplasm "HPA070252: AB_2686242" "unprognostic (2.19e-1)" "unprognostic (3.07e-1)" "unprognostic (3.07e-2)" "unprognostic (2.71e-1)" "unprognostic (8.78e-2)" "unprognostic (7.03e-2)" "unprognostic (1.23e-3)" "unprognostic (1.02e-1)" "unprognostic (1.43e-1)" "unprognostic (1.65e-1)" "unprognostic (3.96e-3)" "unprognostic (1.47e-1)" "unprognostic (1.71e-3)" "unprognostic (3.69e-2)" "unprognostic (1.10e-2)" "unprognostic (7.85e-2)" "unprognostic (9.72e-3)" 4.8 9.7 10.0 1.1 11.5 0.4 4.9 16.4 13.9 6.3 1.4 9.6 0.7 6.4 0.6 2.5 5.1 2.1 91.2 10.6 9.1 4.2 0.3 2.1 0.5 11.0 10.7 8.7 2.3 1.2 4.7 0.5 11.1 4.9 0.5 4.0 3.4 2.5 210.1 1.4 3.1 2.7 8.8 2.4 3.1 5.0 11.7 0.4 1.8 74.4 0.3 6.7 4.0 11.0 0.0 0.0 2.2 11.1 11.4 8.6 2.3 1.7 1.2 0.3 0.0 0.0 0.0 0.0 0.3 4.5 2.4 0.0 0.2 0.0 0.1 0.0 1.9 0.0 0.1 3.6 2.8 0.0 0.0 2.9 0.0 3.1 0.0 0.0 0.0 0.0 0.2 0.0 5.2 0.1 0.0 0.1 2.6 0.0 0.0 0.0 0.0 0.0 2.5 0.0 11.3 8.7 0.0 0.1 0.0 0.3 0.3 2.8 0.1 0.1 0.7 0.5 0.0 0.0 0.4 0.0 1.9 0.0 1.8 0.0 2.6 0.0 0.0 1.7 0.0 0.4 0.0 0.0 2.3 0.5 0.2 0.2 0.0 1.3 1.5 1.0 0.0 0.9 10.0 11.5 16.4 13.9 10.6 9.1 11.0 10.7 11.1 8.8 11.7 11.0 1.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 18.8 0.1 0.0 0.0 0.0 0.0 1.8 2.1 0.1 0.1 0.0 1.9 0.0 1.4 0.1 1.7 1.4 0.0 1.3 0.0 0.6 0.7 4.1 0.0 0.1 0.0 0.8 1.1 0.0 0.5 8.4 0.0 0.0 0.0 0.3 0.0 1.7 5.0 2.2 0.0 0.0 0.1 2.6 0.0 0.0 0.0 0.3 0.0 3.8 0.7 0.0 0.0 2.3 0.0 3.7 0.0 7.0 3.0 0.0 0.1 0.0 0.0 0.0 0.2 1.5 0.0 0.0 PLSCR2 ENSG00000163746 "Phospholipid scramblase 2" Q9NRY7 3 146391421-146495991 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 13.2" "Group enriched" "Detected in some" 30 "Early spermatids: 195.5;Late spermatids: 246.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051352 Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "Endoplasmic reticulum, Vesicles" "HPA051352: " "unprognostic (1.11e-1)" "unprognostic (9.83e-2)" "unprognostic (8.94e-3)" "unprognostic (7.53e-3)" "unprognostic (3.81e-2)" "unprognostic (1.51e-2)" "unprognostic (3.67e-2)" "unprognostic (1.84e-2)" "unprognostic (4.11e-1)" "unprognostic (5.52e-3)" "unprognostic (1.73e-1)" "unprognostic (3.16e-1)" "unprognostic (1.88e-4)" "unprognostic (4.06e-1)" "unprognostic (9.71e-2)" "unprognostic (3.02e-1)" "unprognostic (1.23e-2)" 0.2 0.1 0.4 0.3 0.2 1.1 0.3 0.2 0.7 0.1 0.2 0.3 0.2 0.1 1.8 0.2 0.7 0.5 0.0 0.1 0.7 0.6 0.2 0.2 0.1 0.9 0.6 0.1 0.9 0.2 0.1 0.2 0.7 0.3 0.4 0.5 0.3 0.5 0.0 0.0 0.2 0.2 0.6 0.1 0.4 13.2 0.6 0.2 0.5 0.0 0.1 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.0 0.4 0.0 0.5 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.3 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.0 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.1 0.4 0.2 0.2 0.7 0.1 0.7 0.9 0.6 0.7 0.6 0.6 0.6 0.4 0.0 0.0 0.3 0.2 0.3 0.1 0.1 0.6 0.0 1.3 0.6 0.0 1.5 0.2 7.3 0.0 0.2 1.5 0.7 1.9 1.6 195.5 1.4 0.1 0.4 1.8 0.0 1.0 0.6 0.1 0.5 1.5 0.7 0.0 0.4 0.4 0.1 0.1 0.0 1.1 0.3 2.0 0.0 1.1 246.0 1.8 0.6 0.0 1.0 0.0 1.2 0.0 0.0 0.2 0.5 1.0 1.5 0.0 0.3 0.1 1.5 1.4 0.3 0.0 0.7 0.3 5.4 2.6 0.1 0.1 0.0 0.2 0.2 0.9 0.3 PLXNA3 "6.3, Plxn3, PLXN4, SEX, XAP-6" ENSG00000130827 "Plexin A3" P51805 X 154458281-154477779 "Plasma proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 29.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058989 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA 94000 "Cluster 11: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Plasma membrane" Nucleoplasm "HPA058989: AB_2683872" "unprognostic (2.79e-2)" "unprognostic (3.03e-1)" "unprognostic (1.04e-3)" "unprognostic (8.04e-3)" "unprognostic (1.63e-1)" "unprognostic (9.05e-3)" "unprognostic (1.06e-2)" "unprognostic (2.25e-1)" "unprognostic (2.42e-1)" "unprognostic (6.26e-2)" "unprognostic (1.05e-1)" "unprognostic (4.10e-2)" "unprognostic (1.38e-3)" "unprognostic (2.30e-1)" "unprognostic (3.00e-1)" "unprognostic (4.33e-2)" "unprognostic (5.73e-2)" 6.5 7.0 5.7 3.5 6.4 1.7 6.0 7.5 7.2 10.7 5.3 7.5 3.6 8.1 4.3 5.3 8.7 3.9 7.1 5.5 8.6 5.8 2.8 8.4 3.8 6.4 7.3 17.0 7.6 2.0 24.8 3.6 7.2 10.5 2.2 1.5 12.0 3.4 1.7 10.1 7.8 2.6 4.6 8.0 5.5 3.7 9.0 2.2 10.2 1.1 2.6 7.4 9.7 8.6 11.2 2.2 6.3 16.1 6.5 8.3 8.4 15.6 3.3 3.6 4.9 8.2 4.6 2.0 8.2 16.9 8.4 9.6 6.4 7.6 1.3 0.9 4.8 2.0 29.0 4.5 5.2 1.0 8.8 11.3 5.5 5.4 0.4 12.4 4.1 3.2 5.2 1.6 5.7 13.8 1.9 8.4 2.0 3.4 4.9 7.2 0.5 0.7 4.8 7.2 13.2 6.8 5.7 10.3 2.6 4.4 6.2 2.4 10.4 7.8 7.0 0.8 6.7 1.2 0.2 2.9 14.5 1.5 2.1 0.7 0.0 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.2 0.1 0.1 0.2 0.3 0.0 0.0 0.1 0.0 5.7 6.4 7.5 7.2 5.5 8.6 6.4 7.3 7.2 4.6 9.0 8.6 5.2 12.8 7.7 13.4 9.8 8.7 9.0 7.3 9.6 18.7 13.9 10.3 6.5 2.8 6.8 11.0 12.5 3.0 10.3 15.9 0.0 11.5 0.1 14.4 23.2 3.9 7.2 0.0 6.5 5.8 7.2 11.0 17.9 30.4 8.8 21.3 2.9 1.6 8.5 5.0 5.4 15.1 0.0 3.5 9.2 0.8 11.5 10.5 14.2 6.5 4.7 6.5 4.1 6.0 4.1 13.6 11.4 8.6 8.5 10.3 9.4 1.5 10.9 7.8 13.1 26.5 9.4 0.9 2.3 8.1 7.4 9.3 13.2 2.5 9.6 8.2 PMAIP1 "APR, NOXA" ENSG00000141682 "Phorbol-12-myristate-13-acetate-induced protein 1" Q13794 18 59899996-59904305 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 88.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 803.1;Endometrial ciliated cells: 463.6;Glandular and luminal cells: 529.8;Squamous epithelial cells: 474.5;Suprabasal keratinocytes: 691.2;Urothelial cells: 569.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 169.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 169.8" "Cell line enhanced" "Detected in many" "GAMG: 207.5;U-138 MG: 202.1" HPA051063 Uncertain Uncertain Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" Vesicles "HPA051063: AB_2681330" "unprognostic (1.35e-3)" "unprognostic (5.02e-2)" "unprognostic (5.57e-2)" "unprognostic (4.88e-2)" "unprognostic (6.65e-3)" "unprognostic (3.76e-2)" "unprognostic (2.00e-3)" "unprognostic (1.26e-2)" "unprognostic (4.41e-2)" "unprognostic (6.12e-2)" "unprognostic (8.47e-3)" "unprognostic (5.56e-2)" "prognostic unfavorable (3.15e-6)" "unprognostic (2.53e-1)" "unprognostic (7.68e-2)" "unprognostic (8.74e-2)" "unprognostic (1.09e-1)" 2.0 0.7 2.8 8.0 2.7 88.1 3.9 2.6 5.1 6.5 3.0 2.5 3.7 5.4 0.2 13.7 2.9 8.0 0.9 2.6 2.8 2.3 2.1 3.8 14.7 2.8 2.7 0.7 1.2 14.8 16.7 13.4 3.0 3.6 3.4 2.0 3.6 1.3 1.5 24.1 3.9 1.9 2.7 4.6 2.5 3.1 3.7 12.1 2.1 1.5 14.2 17.3 7.9 2.4 26.6 17.4 5.2 1.6 8.8 69.0 19.8 125.4 84.1 71.5 70.7 1.7 32.5 104.6 17.0 23.5 207.5 38.4 21.0 11.8 70.4 33.7 154.5 19.4 26.0 4.6 87.6 67.1 28.2 28.7 30.8 93.8 48.5 26.1 24.0 46.7 26.7 17.5 24.1 2.6 53.8 20.1 151.7 2.7 32.7 54.1 28.8 39.1 41.9 24.2 39.7 32.7 6.1 3.2 71.5 56.1 5.3 54.6 90.6 202.1 54.0 10.3 141.4 2.8 0.3 92.1 16.8 37.6 48.5 169.8 16.7 103.6 10.9 26.2 9.6 33.8 5.0 6.8 12.1 25.0 4.1 5.9 53.5 6.3 32.1 10.2 25.2 15.1 2.8 2.7 2.6 5.1 2.6 2.8 2.8 2.7 3.0 2.7 3.7 2.4 29.2 32.1 25.7 0.7 175.3 803.1 316.2 236.4 415.4 0.2 111.8 82.0 4.7 12.8 129.6 3.7 2.1 120.3 125.3 141.1 0.0 54.7 0.8 463.6 48.8 48.5 133.4 5.5 0.0 67.0 14.7 32.9 168.2 529.8 31.8 11.8 7.9 0.5 89.5 0.0 0.0 146.8 181.0 37.2 363.3 1.1 0.9 140.6 74.7 7.5 142.4 0.3 34.0 0.0 0.2 100.1 123.6 1.2 63.1 265.7 94.7 0.5 101.5 0.7 0.0 10.8 32.0 0.3 19.8 474.5 691.2 315.2 117.0 19.8 122.2 569.2 PMEPA1 "STAG1, TMEPAI" ENSG00000124225 "Prostate transmembrane protein, androgen induced 1" Q969W9 20 57648392-57711536 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Signal transduction inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 110.8" "Cell type enhanced" "Detected in many" "Ductal cells: 339.6;Muller glia cells: 325.9;Pancreatic endocrine cells: 827.5" "Cancer enhanced" "Detected in all" "prostate cancer: 157.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "naive B-cell: 6.3;plasmacytoid DC: 23.9" "Group enriched" "Detected in many" 8 "B-cells: 6.3;dendritic cells: 23.9" "Cell line enhanced" "Detected in many" "SiHa: 206.1;U-2 OS: 129.9;U-251 MG: 481.8;WM-115: 237.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072291 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Vesicles "HPA072291: AB_2686509" "unprognostic (2.72e-3)" "prognostic unfavorable (2.45e-4)" "unprognostic (5.77e-2)" "unprognostic (1.73e-1)" "unprognostic (6.61e-2)" "unprognostic (2.11e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.73e-5)" "unprognostic (5.53e-1)" "unprognostic (1.32e-3)" "unprognostic (7.83e-3)" "unprognostic (2.02e-1)" "prognostic unfavorable (2.87e-7)" "unprognostic (1.16e-1)" "unprognostic (2.35e-1)" "unprognostic (9.87e-3)" "prognostic unfavorable (7.60e-4)" 50.5 14.5 24.2 14.2 75.5 1.3 25.1 38.8 29.9 94.8 1.8 30.7 6.5 48.4 7.1 7.6 19.9 26.0 29.2 24.0 28.3 16.2 3.8 21.8 7.4 32.9 34.1 14.9 31.3 5.0 13.5 3.9 38.8 110.8 8.4 23.6 30.5 20.6 33.2 18.1 12.6 28.8 27.0 6.6 12.2 5.3 36.1 2.4 13.6 13.6 8.9 13.1 29.6 26.2 32.2 75.4 2.3 3.9 2.4 0.0 0.8 4.9 0.2 1.7 0.8 1.5 97.4 0.2 17.7 7.4 51.8 121.1 1.6 100.8 1.3 1.0 4.1 0.0 23.2 0.1 1.5 0.3 0.8 1.2 55.8 4.4 12.1 16.5 13.0 67.8 0.8 1.2 6.2 66.1 3.8 0.7 9.4 15.0 9.6 0.3 36.0 11.3 24.2 0.0 17.7 13.7 206.1 120.3 15.1 5.6 18.8 4.1 33.1 17.9 129.9 1.9 481.8 5.9 0.8 0.5 8.1 1.1 237.1 0.0 0.4 0.0 0.0 0.0 0.0 2.6 0.8 0.2 0.1 6.3 1.8 1.2 0.1 0.0 0.1 23.9 0.5 0.6 24.2 75.5 38.8 29.9 24.0 28.3 32.9 34.1 38.8 27.0 36.1 26.2 59.4 57.7 32.3 4.9 32.7 167.0 143.1 120.6 30.7 59.0 38.0 23.0 23.2 125.8 31.7 11.0 2.1 0.2 27.8 57.3 3.9 339.6 1.2 33.4 88.8 55.6 10.1 0.0 19.1 62.5 4.1 40.5 5.1 80.2 59.8 17.5 24.7 0.5 6.1 1.7 32.7 16.9 14.2 3.5 68.0 2.7 3.1 13.4 32.0 31.9 5.8 325.9 0.0 17.6 9.0 827.5 54.2 21.8 25.3 203.1 6.2 2.7 10.1 11.5 72.3 43.8 155.2 0.2 8.8 10.0 178.4 0.1 17.8 9.1 19.3 87.5 PMF1 ENSG00000160783 "Polyamine modulated factor 1" Q6P1K2 1 156212993-156240042 "Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034583, HPA071854" Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm Vesicles "HPA034583: AB_2674234, HPA071854: AB_2686459" "unprognostic (1.17e-2)" "unprognostic (3.76e-3)" "unprognostic (2.58e-2)" "unprognostic (5.67e-2)" "unprognostic (3.86e-2)" "unprognostic (2.22e-2)" "unprognostic (6.44e-2)" "unprognostic (1.32e-1)" "unprognostic (3.13e-1)" "unprognostic (1.26e-2)" "unprognostic (1.41e-2)" "unprognostic (9.29e-2)" "unprognostic (5.22e-2)" "unprognostic (2.51e-2)" "unprognostic (1.33e-1)" "unprognostic (1.76e-1)" "unprognostic (1.62e-2)" 39.3 39.6 33.5 29.6 35.9 73.7 42.8 35.1 39.5 47.2 33.0 38.3 30.6 42.6 24.4 50.0 34.8 26.0 69.7 33.3 34.7 56.6 62.3 38.8 46.8 37.1 34.9 42.9 39.4 56.3 34.9 29.9 36.5 47.2 26.8 16.8 42.9 27.1 113.3 54.2 36.7 28.6 35.0 52.5 43.6 15.1 34.9 45.6 50.7 89.7 39.7 39.4 41.7 38.6 68.2 82.5 86.8 66.1 16.1 33.5 67.3 34.6 48.7 91.4 75.4 101.6 95.3 62.2 73.3 44.5 31.6 44.4 88.1 57.7 47.0 44.6 104.6 46.3 59.3 91.8 33.3 65.8 61.3 30.2 57.2 41.2 43.0 36.3 69.9 44.7 69.9 70.1 45.0 138.2 69.2 84.7 151.5 99.6 72.2 75.2 46.3 123.6 97.2 50.5 79.0 99.5 57.4 65.4 45.6 63.2 106.1 79.7 40.7 39.4 50.5 44.4 69.4 52.0 58.1 123.7 31.9 63.1 55.7 18.4 85.7 40.5 43.9 60.6 39.6 54.0 43.0 41.4 70.0 45.6 41.5 42.0 59.9 49.5 55.2 95.9 75.5 77.7 33.5 35.9 35.1 39.5 33.3 34.7 37.1 34.9 36.5 35.0 34.9 38.6 25.5 19.2 25.1 0.0 38.2 49.8 87.2 108.6 3.4 12.3 39.5 33.4 11.9 51.5 57.4 75.4 12.5 136.3 63.4 21.5 176.1 98.0 5.3 22.1 26.3 41.5 49.1 13.2 0.0 99.0 115.7 34.7 8.6 36.5 45.0 50.3 47.2 56.7 80.5 8.4 0.0 46.6 61.1 40.3 43.9 6.0 39.1 34.2 85.4 0.0 59.6 71.2 43.3 0.0 0.0 81.6 52.1 28.2 11.7 51.5 44.7 120.1 15.6 28.8 26.3 36.6 35.7 14.7 33.4 7.6 51.0 157.5 47.3 66.1 52.5 83.8 PMF1-BGLAP ENSG00000260238 "PMF1-BGLAP readthrough" 1 156212982-156243332 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Distal tubular cells: 3.9;Proximal tubular cells: 2.5;Sertoli cells: 6.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034583, HPA071854" Approved Nucleoplasm,Vesicles NA NA "Cluster 24: B-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 59: Non-specific - Transcription" Nucleoplasm Vesicles "HPA034583: AB_2674234, HPA071854: AB_2686459" "unprognostic (8.15e-2)" "unprognostic (1.80e-1)" "unprognostic (8.56e-4)" "unprognostic (1.65e-2)" "unprognostic (4.01e-2)" "unprognostic (1.99e-1)" "prognostic unfavorable (1.50e-4)" "unprognostic (4.66e-2)" "unprognostic (1.28e-1)" "unprognostic (8.52e-3)" "unprognostic (1.85e-4)" "unprognostic (2.39e-1)" "prognostic unfavorable (3.22e-4)" "unprognostic (1.12e-1)" "unprognostic (2.37e-1)" "unprognostic (5.31e-3)" "unprognostic (2.36e-1)" 7.0 9.0 6.8 2.2 7.1 4.6 5.0 7.6 11.5 10.8 7.3 9.5 2.8 6.7 5.1 5.2 7.3 3.6 16.2 6.8 7.3 8.6 7.6 4.9 3.4 6.8 6.7 10.0 5.7 3.8 10.3 4.7 6.8 11.0 1.6 4.9 7.7 4.1 13.3 4.3 4.6 2.9 6.8 6.5 6.5 3.5 6.9 3.0 8.7 10.0 2.5 6.8 7.2 8.4 8.9 8.4 11.6 7.8 3.0 7.4 5.2 7.8 5.0 7.5 6.0 6.6 7.9 7.7 12.8 7.0 3.1 6.0 10.8 10.1 3.5 13.4 18.4 5.3 8.5 12.5 14.5 5.3 9.3 9.7 9.3 7.0 6.2 6.9 7.3 7.0 5.4 12.4 5.0 11.1 4.7 11.3 23.7 5.9 16.1 8.7 4.5 11.4 4.8 4.2 7.9 10.3 5.2 2.0 13.6 10.0 11.8 20.9 7.9 3.7 3.8 4.6 7.0 7.4 9.4 11.5 4.7 6.9 7.5 2.3 5.7 3.1 2.8 3.9 2.9 2.7 4.6 4.3 4.2 7.7 6.2 3.6 6.4 3.0 4.3 4.4 5.6 5.7 6.8 7.1 7.6 11.5 6.8 7.3 6.8 6.7 6.8 6.8 6.9 8.4 0.6 0.0 1.5 0.3 1.3 0.0 0.5 0.1 1.8 0.0 0.5 0.4 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 3.9 0.4 0.0 0.4 1.1 0.3 0.0 1.3 0.2 0.0 0.2 1.1 0.5 0.4 0.0 0.6 0.7 0.5 0.4 0.0 0.3 0.3 0.0 0.6 0.0 0.1 1.5 0.8 0.0 0.0 0.1 0.0 0.0 1.0 0.3 0.1 0.1 0.4 2.4 0.1 0.4 2.5 1.5 0.0 6.6 0.3 0.6 0.3 0.5 2.2 0.0 1.0 1.3 0.2 0.6 0.3 PODXL "Gp200, PC, PCLP" ENSG00000128567 "Podocalyxin like" O00592 7 131500262-131558217 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 96.2" "Cell type enhanced" "Detected in many" "Adipocytes: 165.8;Cone photoreceptor cells: 87.6;Endothelial cells: 181.1;Glandular and luminal cells: 121.3;Microglial cells: 92.8;Rod photoreceptor cells: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 295.8;NTERA-2: 509.7;SuSa: 640.8;TIME: 474.0;U-251 MG: 226.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002110, CAB016169, HPA045507, CAB062558, CAB068219, CAB068220" Enhanced Supported "Vesicles,Plasma membrane,Centriolar satellite" NA NA 33000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Centriolar satellite" Vesicles "CAB016169: AB_628165, CAB062558: AB_2665627, CAB068219: AB_2665618, CAB068220: AB_2665619, HPA002110: AB_1855512, HPA045507: AB_2679356" "unprognostic (1.26e-1)" "unprognostic (7.68e-2)" "unprognostic (8.28e-3)" "unprognostic (6.46e-3)" "unprognostic (5.16e-3)" "unprognostic (5.85e-2)" "unprognostic (1.63e-2)" "unprognostic (1.05e-1)" "unprognostic (7.95e-3)" "unprognostic (3.52e-1)" "unprognostic (9.20e-3)" "unprognostic (3.40e-1)" "prognostic favorable (2.89e-4)" "unprognostic (2.56e-1)" "unprognostic (8.78e-3)" "unprognostic (3.55e-2)" "unprognostic (1.03e-1)" 20.8 6.8 27.7 8.9 26.5 0.3 21.9 25.2 34.4 26.0 19.0 8.4 5.1 27.5 5.6 8.1 49.0 14.5 29.1 25.2 25.3 96.2 3.0 31.8 5.6 29.2 28.1 6.1 26.0 18.9 1.1 29.3 29.5 8.7 8.6 67.8 16.1 18.9 15.3 4.8 6.2 28.9 22.0 5.6 5.6 2.4 42.0 3.7 28.5 26.1 6.1 9.6 1.0 22.0 50.9 18.9 42.6 16.3 0.5 0.0 2.6 5.4 4.2 16.9 6.1 121.4 83.1 0.3 109.7 295.8 57.1 34.9 34.3 0.7 15.3 5.4 17.3 0.2 115.0 2.7 1.1 4.2 4.0 0.2 0.4 50.5 0.8 9.4 146.3 1.5 10.5 1.8 16.9 18.0 0.5 1.3 509.7 10.0 43.6 16.2 73.1 15.8 1.6 16.6 34.3 8.9 34.7 7.0 0.2 640.8 4.1 2.2 474.0 6.8 26.6 72.5 226.1 2.5 4.5 1.2 27.1 20.1 48.4 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.7 26.5 25.2 34.4 25.2 25.3 29.2 28.1 29.5 22.0 42.0 22.0 165.8 6.4 9.9 3.6 2.4 5.2 0.9 14.0 0.6 9.7 33.3 20.7 22.9 4.3 25.4 27.6 87.6 0.8 1.0 1.0 0.0 4.6 0.8 44.8 13.0 181.1 2.4 2.7 9.4 18.3 0.4 9.2 1.1 121.3 2.5 2.2 65.0 1.0 0.4 5.0 3.3 12.9 4.1 0.9 9.6 1.3 4.7 2.6 5.4 92.8 0.7 10.6 0.0 7.1 3.1 42.7 0.8 0.4 4.3 3.6 0.7 0.8 10.3 188.4 0.0 6.3 8.4 0.3 1.1 1.3 3.1 0.7 3.3 1.9 2.7 5.8 PODXL2 "endoglycan, PODLX2" ENSG00000114631 "Podocalyxin like 2" Q9NZ53 3 127629185-127672802 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.6;pituitary gland: 59.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 96.3;Early spermatids: 73.5;Horizontal cells: 82.4;Late spermatids: 153.1;Spermatogonia: 80.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPMI-8226: 118.1;SCLC-21H: 167.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024934, HPA042265" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" Vesicles "CAB024934: , HPA042265: AB_2677920" "unprognostic (2.07e-2)" "unprognostic (2.34e-1)" "unprognostic (7.02e-2)" "unprognostic (1.07e-2)" "unprognostic (9.74e-2)" "unprognostic (1.79e-2)" "unprognostic (8.97e-3)" "unprognostic (1.81e-1)" "unprognostic (3.89e-1)" "unprognostic (2.67e-1)" "unprognostic (4.05e-3)" "unprognostic (3.48e-1)" "unprognostic (2.91e-1)" "unprognostic (1.90e-1)" "unprognostic (2.67e-2)" "unprognostic (1.94e-2)" "unprognostic (1.46e-3)" 3.8 17.3 45.0 2.7 39.9 1.8 8.8 34.1 50.9 2.9 1.9 9.4 7.2 4.4 2.3 4.2 4.3 4.5 4.1 42.3 65.6 7.2 1.6 2.0 2.2 49.2 50.9 11.2 13.5 5.3 59.0 1.0 54.6 13.1 8.2 21.6 24.9 2.0 3.2 7.6 6.7 1.8 32.9 2.0 14.1 30.8 53.6 1.9 5.5 1.8 2.7 3.1 2.8 40.5 0.3 13.8 37.5 89.2 0.0 0.0 55.2 4.3 0.2 7.9 1.6 28.7 1.5 34.0 33.3 0.6 12.1 0.2 30.9 0.0 0.7 0.2 63.3 0.7 30.9 29.3 1.2 78.1 75.7 1.5 6.6 0.2 0.0 20.9 2.2 0.2 45.6 0.2 2.9 17.6 0.3 0.3 56.2 7.9 66.6 0.2 1.0 118.1 10.9 3.9 167.0 94.0 40.9 86.3 77.2 3.7 22.0 39.2 0.4 0.2 17.2 1.5 27.3 0.2 0.0 26.9 0.9 50.1 25.1 0.0 0.0 0.0 0.1 0.2 0.3 0.3 0.6 0.1 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.6 0.5 0.1 45.0 39.9 34.1 50.9 42.3 65.6 49.2 50.9 54.6 32.9 53.6 40.5 1.6 0.0 1.1 10.4 3.4 5.5 3.7 1.3 9.1 96.3 17.5 18.4 0.5 4.3 1.7 9.2 31.3 2.2 4.4 14.3 1.9 6.8 73.5 8.7 2.5 2.2 63.5 5.5 21.3 20.1 5.9 8.2 25.0 12.3 1.3 9.5 0.7 0.7 1.3 82.4 57.7 23.2 4.1 1.3 2.8 153.1 8.7 1.6 21.4 5.6 8.1 19.0 6.2 29.1 12.5 12.9 16.7 5.7 10.4 9.9 10.8 2.9 1.7 49.9 6.6 3.8 9.8 20.4 80.4 10.0 5.5 1.5 3.3 7.5 21.8 3.1 POGLUT3 "KDELC2, MGC33424" ENSG00000178202 "Protein O-glucosyltransferase 3" Q7Z4H8 11 108472112-108498384 "Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 6.8;Cardiomyocytes: 13.1;Cytotrophoblasts: 27.6;Extravillous trophoblasts: 14.5;Fibroblasts: 14.7;Hofbauer cells: 18.0;Syncytiotrophoblasts: 21.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039315, HPA039817, HPA066134" Approved Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 32: U-937 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm Vesicles "HPA039315: AB_10960861, HPA039817: AB_10966564, HPA066134: AB_2685624" "unprognostic (1.29e-1)" "unprognostic (2.80e-1)" "unprognostic (3.62e-1)" "unprognostic (7.65e-3)" "unprognostic (6.56e-3)" "unprognostic (1.02e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (6.04e-2)" "unprognostic (3.49e-3)" "unprognostic (1.49e-1)" "unprognostic (6.00e-3)" "unprognostic (4.08e-3)" "unprognostic (1.66e-3)" "unprognostic (1.85e-2)" "unprognostic (1.31e-1)" "unprognostic (1.90e-1)" "prognostic unfavorable (6.27e-5)" 24.6 13.2 5.0 17.3 5.0 7.6 16.2 4.6 5.4 33.6 7.0 16.8 9.4 35.0 27.3 21.0 23.0 21.7 15.2 4.2 5.9 15.6 13.2 16.0 10.4 5.5 6.1 36.5 8.3 25.2 5.4 32.7 5.4 28.4 16.9 5.8 13.9 28.4 5.5 13.7 11.2 37.1 5.3 12.4 11.3 5.8 5.5 16.4 12.1 13.9 9.5 22.5 18.8 6.0 10.9 12.4 46.5 47.8 76.5 88.5 44.8 47.0 43.7 66.0 71.1 58.9 78.1 0.1 28.6 61.6 73.1 7.9 35.6 1.2 69.3 19.4 27.4 18.1 12.1 27.2 30.8 47.7 0.2 51.1 14.6 35.0 1.0 40.1 56.6 0.3 41.5 0.3 101.0 7.9 30.9 27.2 20.3 11.5 34.8 1.5 72.5 0.2 12.3 30.3 9.7 29.5 89.1 6.2 13.3 21.4 42.3 18.0 56.8 127.0 24.9 10.8 49.7 0.4 0.1 0.3 32.6 48.9 103.1 0.1 0.1 0.0 2.0 0.7 1.7 0.2 1.0 1.7 0.5 0.3 1.0 1.5 0.1 1.9 0.4 1.0 0.9 0.5 5.0 5.0 4.6 5.4 4.2 5.9 5.5 6.1 5.4 5.3 5.5 6.0 6.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.0 27.6 2.8 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 14.5 14.7 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 21.2 0.5 0.0 0.0 0.0 POLB ENSG00000070501 "DNA polymerase beta" P06746 8 42338454-42371808 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Lyase, Nucleotidyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 254.5;Late spermatids: 133.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 280.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011616, HPA049104, HPA069013" Enhanced Uncertain Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "CAB011616: AB_731977, HPA049104: AB_2680632, HPA069013: " "unprognostic (1.67e-1)" "unprognostic (2.68e-3)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.46e-4)" "unprognostic (8.49e-2)" "unprognostic (2.64e-2)" "unprognostic (4.24e-2)" "unprognostic (1.02e-1)" "unprognostic (2.31e-2)" "unprognostic (1.99e-1)" "unprognostic (4.57e-2)" "unprognostic (4.77e-1)" "prognostic unfavorable (2.15e-5)" "unprognostic (1.06e-2)" "unprognostic (1.40e-1)" "unprognostic (4.22e-2)" "prognostic favorable (5.65e-4)" 12.4 17.5 26.6 13.5 27.4 51.3 27.4 82.3 35.5 18.9 24.3 12.3 10.8 12.9 19.7 26.5 13.2 17.4 26.1 28.1 29.0 18.0 33.9 14.2 20.2 27.1 27.8 20.4 16.9 18.8 26.7 11.1 28.9 24.8 13.2 18.0 30.3 11.3 85.3 23.1 10.8 10.6 27.6 17.2 14.0 53.1 30.2 24.8 14.2 70.0 22.2 30.8 18.9 28.9 40.2 23.5 40.6 80.4 21.8 20.7 33.8 25.2 29.3 41.5 37.7 33.1 46.0 36.4 31.1 16.5 43.4 20.0 34.1 29.5 50.3 23.8 36.7 26.5 18.2 45.3 34.1 18.6 280.6 18.8 34.4 30.1 35.4 51.8 32.1 77.2 58.4 22.4 40.3 23.6 78.0 52.6 54.4 48.4 26.7 44.2 40.8 31.4 78.4 32.1 22.7 41.8 29.9 19.9 79.0 41.4 52.5 31.5 17.8 19.1 27.0 48.8 24.6 32.5 58.4 52.2 19.3 39.4 52.2 47.6 15.1 48.1 12.0 18.8 13.3 12.2 12.5 13.0 15.7 11.1 14.1 13.3 63.6 22.2 26.3 84.9 19.3 11.5 26.6 27.4 82.3 35.5 28.1 29.0 27.1 27.8 28.9 27.6 30.2 28.9 13.9 3.2 13.6 6.8 20.2 16.8 30.1 14.2 31.3 2.9 14.3 15.1 21.6 7.2 20.7 7.3 8.4 7.5 51.9 3.1 5.9 11.7 254.5 13.8 7.7 12.5 6.0 7.6 15.8 9.6 7.0 9.7 10.2 9.9 23.4 12.7 8.6 12.7 7.4 6.7 20.3 5.4 4.1 5.7 9.9 133.9 7.2 18.2 7.2 19.7 11.2 8.3 13.4 12.5 16.7 33.6 5.8 3.8 21.9 41.6 4.3 6.8 16.4 4.4 0.0 6.6 12.3 19.4 15.4 27.3 20.0 11.1 16.2 7.8 6.6 31.6 POLE2 DPE2 ENSG00000100479 "DNA polymerase epsilon 2, accessory subunit" P56282 14 49643555-49688422 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "DNA replication" DNA-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.2" "Cell type enhanced" "Detected in many" "Erythroid cells: 21.0;Spermatogonia: 24.4" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" HPA027555 Uncertain Supported "Nucleoplasm,Nuclear bodies,Vesicles" No No "Cluster 48: NK-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nuclear bodies" Vesicles "HPA027555: AB_10610282" "unprognostic (1.42e-1)" "unprognostic (6.57e-3)" "unprognostic (3.53e-2)" "unprognostic (7.44e-2)" "unprognostic (2.04e-2)" "unprognostic (4.99e-3)" "unprognostic (7.60e-3)" "unprognostic (2.32e-3)" "unprognostic (1.10e-3)" "unprognostic (2.69e-2)" "unprognostic (1.88e-2)" "unprognostic (1.37e-3)" "unprognostic (5.13e-11)" "unprognostic (9.97e-2)" "unprognostic (1.66e-1)" "unprognostic (1.27e-1)" "unprognostic (1.50e-3)" 0.9 0.9 0.5 5.1 0.3 18.2 3.0 0.5 0.6 2.1 0.0 3.8 2.5 2.5 0.7 3.7 1.0 0.9 0.6 0.2 0.2 0.7 3.1 1.2 5.1 0.2 0.4 1.0 0.8 0.7 0.5 3.0 0.2 1.4 4.5 3.0 1.0 0.7 0.5 3.5 3.6 2.3 0.3 1.5 2.1 4.1 0.2 5.5 0.9 0.9 6.2 1.4 1.9 0.6 37.2 18.6 34.3 16.3 1.7 9.9 18.2 20.4 10.4 31.9 36.7 19.3 27.5 23.6 11.6 11.6 17.5 22.3 35.3 12.8 36.9 27.4 19.6 35.4 20.6 23.9 0.8 41.2 14.6 2.8 0.8 18.5 2.9 4.1 19.0 30.5 30.9 14.3 31.6 32.7 43.6 28.4 20.2 30.9 42.6 35.9 31.7 21.0 11.6 20.6 24.8 14.3 20.5 11.9 6.7 16.5 24.5 15.8 6.7 5.3 38.5 21.4 16.9 10.7 22.7 52.7 9.8 30.1 20.9 0.0 0.0 0.2 0.2 0.0 0.1 0.3 0.2 0.4 0.1 0.2 0.0 0.2 0.0 0.9 0.0 0.2 0.7 0.1 0.5 0.3 0.5 0.6 0.2 0.2 0.2 0.4 0.2 0.3 0.2 0.6 2.0 3.2 0.5 4.2 2.4 4.8 2.1 1.9 2.2 0.8 1.5 1.1 1.2 1.5 1.3 0.0 0.0 9.1 1.0 2.2 0.0 1.3 1.2 0.8 2.6 1.5 1.2 21.0 9.5 1.5 10.6 2.7 1.1 1.5 0.0 4.3 5.0 5.5 5.5 0.0 11.9 2.8 0.0 1.9 1.6 0.8 1.5 1.1 1.8 7.5 1.0 2.0 4.1 12.1 11.5 0.8 0.5 3.0 5.7 1.9 1.1 1.2 0.9 3.1 0.0 2.1 7.4 5.3 24.4 6.0 3.7 3.4 1.7 1.8 4.7 1.5 POLR3H "C25, KIAA1665, RPC8" ENSG00000100413 "RNA polymerase III subunit H" Q9Y535 22 41525799-41544606 "Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 163.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046787 Approved Supported Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Vesicles, Centrosome" "HPA046787: AB_2679806" "unprognostic (1.55e-1)" "unprognostic (6.74e-2)" "unprognostic (1.06e-1)" "unprognostic (3.87e-3)" "unprognostic (9.57e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.05e-2)" "unprognostic (1.33e-2)" "unprognostic (5.43e-2)" "prognostic favorable (5.41e-4)" "unprognostic (6.40e-2)" "unprognostic (1.54e-1)" "unprognostic (2.94e-2)" "unprognostic (1.49e-1)" "unprognostic (4.00e-2)" "unprognostic (1.70e-1)" 16.6 21.0 40.4 8.5 38.9 5.4 15.1 38.0 49.5 11.0 33.3 13.4 4.8 14.0 9.0 16.4 15.8 7.9 18.3 39.5 38.6 13.5 26.7 14.2 10.0 41.1 41.7 18.5 12.2 11.9 18.2 6.5 38.1 15.4 5.2 7.0 11.5 10.7 13.8 12.1 9.7 11.7 40.1 10.9 13.4 16.2 41.3 8.0 14.1 9.0 7.7 14.2 9.8 39.4 36.4 23.8 21.4 32.7 23.0 20.9 14.8 30.5 27.3 49.0 39.3 47.9 12.0 30.8 21.9 49.9 27.8 17.8 39.8 48.1 30.6 26.3 50.1 18.4 37.1 23.7 23.9 75.3 30.8 26.3 30.8 64.9 17.4 18.8 23.5 29.3 39.5 19.9 28.0 34.4 19.3 20.1 15.6 49.8 28.1 30.0 16.9 32.6 22.9 21.7 21.2 12.5 37.0 39.7 19.3 13.7 15.6 21.1 22.7 29.8 30.7 49.8 39.8 16.7 28.6 46.6 49.5 26.8 28.9 0.1 12.5 0.2 8.8 18.3 12.6 16.6 8.7 10.4 14.2 13.9 11.6 9.7 0.6 5.4 18.6 13.3 5.8 9.9 40.4 38.9 38.0 49.5 39.5 38.6 41.1 41.7 38.1 40.1 41.3 39.4 6.1 0.0 32.0 15.7 14.8 17.7 12.0 19.0 13.6 18.8 24.9 23.4 6.4 14.3 19.8 16.5 16.7 32.9 7.9 5.0 46.9 30.4 42.6 12.7 15.4 10.3 14.3 19.1 10.0 29.6 30.9 14.8 13.3 8.9 11.4 13.1 9.7 33.3 30.5 21.9 7.1 4.8 14.2 9.5 11.0 163.9 16.8 10.2 24.9 1.9 19.6 24.1 18.6 2.0 6.7 27.6 6.6 20.3 21.8 16.8 4.1 40.7 12.7 20.9 0.0 17.9 16.8 51.6 50.9 21.2 25.6 17.9 10.3 21.2 9.5 11.8 POP7 "RPP2, RPP20" ENSG00000172336 "POP7 homolog, ribonuclease P/MRP subunit" O75817 7 100706121-100707486 "Enzymes, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021007 Uncertain Supported Nucleoli,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoli, Vesicles" "HPA021007: AB_10963575" "unprognostic (3.19e-1)" "unprognostic (2.45e-2)" "unprognostic (2.72e-2)" "unprognostic (1.80e-3)" "unprognostic (6.47e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (4.99e-5)" "unprognostic (2.98e-2)" "unprognostic (2.28e-1)" "unprognostic (3.12e-2)" "unprognostic (9.50e-2)" "unprognostic (3.88e-1)" "prognostic unfavorable (6.02e-4)" "unprognostic (1.05e-2)" "unprognostic (1.44e-1)" "unprognostic (6.21e-2)" "unprognostic (6.73e-2)" 25.6 31.7 30.1 18.1 31.6 33.9 26.6 33.4 38.6 24.2 23.8 27.9 19.3 27.7 11.0 34.0 21.3 9.8 37.6 32.3 30.8 25.8 67.1 18.2 17.3 30.1 27.8 18.1 31.3 16.6 22.8 16.6 30.8 22.6 9.2 9.6 29.0 13.5 69.0 50.2 22.3 12.1 29.4 22.7 26.4 12.5 29.1 15.6 16.8 31.9 12.0 25.4 24.9 33.9 115.7 115.3 47.2 78.4 25.1 23.9 92.0 65.6 32.4 73.7 73.1 159.8 71.0 97.5 105.1 30.0 81.4 70.4 70.1 79.5 36.8 82.7 212.4 44.9 75.0 166.5 42.1 69.2 49.8 27.6 30.2 76.2 74.8 20.9 41.6 68.9 157.4 77.8 39.8 330.4 158.0 232.9 135.2 77.8 164.4 123.6 50.0 159.4 45.3 65.2 90.4 92.3 54.5 156.2 78.7 42.0 50.0 66.2 41.3 92.0 117.7 191.0 127.6 34.0 99.4 175.8 61.0 115.1 104.6 106.3 63.2 72.4 54.7 64.7 50.7 60.3 54.6 54.3 55.3 47.7 49.5 52.0 39.0 78.9 70.3 51.2 69.8 62.5 30.1 31.6 33.4 38.6 32.3 30.8 30.1 27.8 30.8 29.4 29.1 33.9 30.5 19.2 17.0 2.9 29.7 105.0 32.0 57.2 56.3 26.1 61.6 64.1 27.9 37.1 31.5 35.0 6.2 148.2 25.8 51.8 93.9 75.4 2.1 31.2 32.3 37.2 40.2 50.1 5.2 87.4 181.3 37.3 25.0 35.1 17.7 32.4 33.5 99.0 66.1 32.0 6.0 61.7 67.1 27.3 40.7 7.9 42.0 22.4 56.9 2.8 38.7 41.8 41.2 4.0 5.8 92.2 47.6 37.2 55.1 75.6 69.8 86.1 27.8 21.3 46.0 29.8 52.2 9.2 45.5 74.7 119.2 139.3 27.2 39.9 55.8 43.5 POR "CYPOR, FLJ26468" ENSG00000127948 "Cytochrome p450 oxidoreductase" P16435 7 75899200-75986855 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Congenital adrenal hyperplasia, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 313.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 489.2;Proximal enterocytes: 274.2;Theca cells: 647.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 328.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004372, HPA010136" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 12000 "Cluster 5: Granulocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Vesicles" Cytosol "CAB004372: AB_627391, HPA010136: AB_1079657" "unprognostic (1.89e-1)" "unprognostic (1.53e-1)" "unprognostic (2.81e-3)" "unprognostic (8.67e-2)" "prognostic unfavorable (8.54e-4)" "unprognostic (1.65e-1)" "unprognostic (1.17e-2)" "unprognostic (4.32e-2)" "unprognostic (1.69e-2)" "unprognostic (1.46e-1)" "unprognostic (1.22e-1)" "unprognostic (2.58e-1)" "unprognostic (1.11e-1)" "unprognostic (9.31e-2)" "unprognostic (1.71e-1)" "unprognostic (3.94e-2)" "unprognostic (9.89e-2)" 53.4 197.4 19.9 32.1 20.7 17.9 44.7 14.1 18.6 42.0 15.5 35.9 105.2 32.1 29.4 53.6 50.2 37.0 43.3 20.7 30.2 38.1 313.3 55.0 19.9 22.2 24.5 52.2 44.5 77.6 71.4 46.3 20.9 31.8 21.9 12.7 29.9 113.1 56.2 43.8 92.4 28.2 16.9 43.8 41.5 25.5 34.7 38.0 131.3 68.1 23.2 36.6 42.3 15.3 59.6 133.0 57.0 106.3 212.9 79.8 98.0 24.4 79.3 44.7 62.3 100.7 257.0 56.1 21.9 53.1 151.8 28.3 76.0 38.4 19.6 48.1 57.9 26.0 36.9 189.4 146.5 26.2 45.5 163.9 47.4 59.2 43.2 36.3 42.3 27.1 79.1 24.0 40.8 90.9 29.0 49.4 71.7 92.9 74.8 41.0 37.6 61.1 50.0 72.8 59.3 57.4 65.4 328.4 91.0 32.6 94.0 44.2 38.6 41.7 45.8 63.6 48.7 23.8 38.3 39.0 59.3 39.8 54.9 65.9 42.6 60.4 20.6 39.6 17.1 11.0 17.5 19.4 45.6 11.2 17.1 14.7 53.8 25.9 30.2 12.5 19.3 36.6 19.9 20.7 14.1 18.6 20.7 30.2 22.2 24.5 20.9 16.9 34.7 15.3 34.3 38.5 39.7 23.2 17.1 17.1 29.4 172.3 13.1 31.4 20.5 14.0 10.9 54.3 201.4 73.5 12.5 99.9 26.0 97.7 1.9 65.0 27.6 62.1 28.0 27.1 19.8 11.8 10.1 29.4 95.0 40.1 67.8 46.6 24.7 121.4 32.2 489.2 67.8 15.2 17.1 41.7 124.1 35.2 16.1 9.5 75.8 47.3 12.4 11.2 20.5 25.9 12.3 11.6 8.8 27.9 102.0 112.5 17.0 20.7 274.2 31.7 178.6 23.0 65.7 32.7 46.9 21.3 30.8 18.2 14.6 193.2 25.4 647.6 44.5 45.9 PORCN "DHOF, MG61, por, PORC, PPN" ENSG00000102312 "Porcupine O-acyltransferase" Q9H237 X 48508962-48520814 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 37.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 68.5;Club cells: 44.2;Pancreatic endocrine cells: 36.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 176.9;LHCN-M2: 60.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049215, HPA058413" Enhanced Approved Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA049215: , HPA058413: AB_2683711" "unprognostic (1.11e-1)" "unprognostic (1.01e-1)" "unprognostic (1.93e-1)" "unprognostic (4.01e-2)" "unprognostic (2.19e-1)" "unprognostic (1.98e-1)" "unprognostic (1.26e-3)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "unprognostic (2.09e-2)" "unprognostic (2.65e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (1.69e-1)" "unprognostic (1.37e-1)" "unprognostic (1.37e-1)" "unprognostic (2.35e-1)" 5.2 37.3 8.7 3.3 8.3 2.9 4.7 7.0 10.6 9.1 4.5 6.3 2.3 7.1 2.1 10.8 5.8 4.6 11.5 11.2 7.0 3.7 1.5 4.6 3.6 7.1 6.6 4.3 3.5 9.8 4.7 2.4 7.2 4.5 1.6 7.4 4.9 11.6 7.6 5.9 3.7 4.6 6.2 4.5 5.2 5.1 7.7 2.3 6.3 3.5 3.3 6.2 7.1 7.8 13.1 15.6 3.8 26.6 15.9 9.4 1.6 3.7 7.7 5.8 3.9 1.8 19.7 1.1 15.9 8.3 6.5 17.3 5.5 176.9 1.8 8.3 1.8 2.2 9.0 3.8 23.4 2.0 22.5 12.2 20.6 16.8 36.0 13.5 5.3 6.4 1.0 12.1 60.8 3.7 2.0 2.8 4.9 4.0 10.4 4.0 4.6 20.5 9.8 5.1 4.2 6.5 30.8 5.9 5.9 2.5 6.7 1.0 3.3 15.0 7.8 36.4 6.8 10.4 6.3 1.5 43.0 4.9 8.7 16.9 5.5 6.8 10.8 4.9 8.5 3.2 7.1 9.0 6.8 3.5 4.7 7.1 1.1 8.4 4.3 3.6 4.9 4.7 8.7 8.3 7.0 10.6 11.2 7.0 7.1 6.6 7.2 6.2 7.7 7.8 5.4 6.4 2.8 5.2 3.8 4.0 5.3 68.5 8.0 15.4 2.9 4.6 3.4 4.3 44.2 16.5 18.8 0.3 7.3 0.8 1.9 6.9 0.2 13.4 3.5 5.7 6.0 1.3 7.8 9.9 1.3 5.0 3.6 17.8 5.7 3.9 5.0 0.7 3.5 8.4 7.6 2.9 12.2 2.7 4.5 0.1 5.6 2.5 3.6 2.8 3.1 10.1 10.3 6.0 2.8 36.4 1.8 4.1 6.3 2.5 0.2 0.7 8.7 15.5 6.6 4.0 4.8 2.9 4.9 4.2 3.8 8.2 6.9 7.5 1.5 6.6 POU2F1 "OCT1, OTF1" ENSG00000143190 "POU class 2 homeobox 1" P14859 1 167220876-167427345 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 270.6;Excitatory neurons: 187.6;Inhibitory neurons: 184.0;Oligodendrocyte precursor cells: 186.0;Oligodendrocytes: 202.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002608, HPA058559, HPA064323" Supported Supported "Nucleoplasm,Endoplasmic reticulum,Vesicles" No No "Cluster 34: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Vesicles" "Endoplasmic reticulum" "CAB002608: , HPA058559: AB_2683756, HPA064323: AB_2685245" "unprognostic (1.74e-1)" "unprognostic (9.33e-2)" "unprognostic (1.28e-2)" "unprognostic (1.40e-3)" "unprognostic (5.78e-3)" "unprognostic (4.26e-2)" "unprognostic (5.67e-6)" "unprognostic (4.47e-2)" "unprognostic (5.14e-1)" "unprognostic (7.94e-3)" "unprognostic (1.95e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (2.98e-5)" "unprognostic (1.89e-1)" "unprognostic (4.02e-1)" "unprognostic (3.42e-1)" "unprognostic (1.17e-2)" 4.0 2.5 5.0 2.2 5.8 3.9 3.4 7.3 5.2 3.6 2.9 3.7 1.3 4.0 2.6 2.7 3.4 1.4 2.6 4.8 3.8 2.9 2.3 3.5 3.0 4.1 4.2 4.1 2.4 3.4 3.6 2.4 3.9 3.2 2.1 12.9 3.0 2.0 4.1 3.5 3.6 1.4 3.8 4.2 2.6 4.3 5.0 3.8 3.3 2.6 3.4 3.4 3.2 4.4 7.4 4.0 14.8 4.5 1.7 1.7 6.1 0.9 1.6 1.7 1.7 8.1 4.2 8.3 3.8 1.5 1.7 5.6 8.8 2.7 2.6 3.3 3.5 5.9 3.9 7.1 1.1 6.5 3.8 1.2 1.6 2.0 3.6 2.1 2.3 5.7 6.4 4.3 2.3 3.7 6.0 4.3 17.4 4.0 2.3 8.7 5.4 3.7 3.1 4.0 9.0 6.9 5.6 4.1 3.7 7.4 4.6 7.9 3.8 3.4 5.3 2.0 3.5 4.4 2.1 18.3 1.6 3.9 4.4 4.6 0.3 0.3 0.2 0.3 0.3 2.0 0.2 0.0 0.4 0.7 0.3 0.2 0.4 0.2 0.3 0.9 0.2 0.4 5.0 5.8 7.3 5.2 4.8 3.8 4.1 4.2 3.9 3.8 5.0 4.4 19.9 12.8 17.2 270.6 25.2 13.4 11.3 9.7 9.6 58.7 12.5 11.8 15.8 14.3 11.6 20.2 102.2 17.8 20.2 12.3 5.9 10.5 26.2 17.7 18.7 19.8 24.1 14.5 187.6 11.6 18.5 17.5 10.2 18.9 19.7 18.7 15.0 13.3 13.3 47.1 184.0 14.3 8.2 52.5 12.4 44.1 25.7 19.9 7.2 114.3 21.7 43.8 14.4 186.0 202.1 16.5 8.0 20.7 33.5 16.1 5.3 8.3 11.5 101.7 26.3 28.4 16.4 17.6 35.7 12.7 11.1 51.7 14.1 11.0 14.5 21.0 POU2F2 "OCT2, OTF2" ENSG00000028277 "POU class 2 homeobox 2" P09086 19 42086110-42196585 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 52.1" "Cell type enhanced" "Detected in many" "B-cells: 225.5;Kupffer cells: 119.6;Langerhans cells: 104.4;Macrophages: 105.0;monocytes: 137.6;Plasma cells: 96.7;Spermatocytes: 75.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 94.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 52.3;Daudi: 113.0;hTEC/SVTERT24-B: 42.7;U-266/70: 75.5;U-266/84: 80.2;U-698: 88.4;U-87 MG: 41.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002513, HPA049056, HPA062096, HPA064404, HPA073998" Enhanced Enhanced Nucleoplasm,Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Vesicles" "CAB002513: AB_442118, HPA049056: AB_2732550, HPA062096: AB_2684681, HPA064404: AB_2685259, HPA073998: " "unprognostic (2.07e-2)" "unprognostic (1.14e-1)" "unprognostic (1.16e-2)" "unprognostic (8.89e-2)" "unprognostic (6.77e-2)" "unprognostic (1.44e-2)" "unprognostic (1.62e-2)" "unprognostic (3.34e-1)" "unprognostic (8.39e-2)" "unprognostic (2.09e-1)" "unprognostic (1.52e-1)" "unprognostic (8.56e-2)" "prognostic unfavorable (7.57e-11)" "unprognostic (2.31e-1)" "unprognostic (1.76e-1)" "unprognostic (2.61e-2)" "unprognostic (1.54e-1)" 2.6 2.8 6.1 28.0 5.9 8.4 1.7 15.5 10.6 1.1 3.8 4.3 3.1 1.2 1.5 2.0 1.6 3.4 0.8 5.8 15.4 1.4 2.0 3.8 52.1 8.0 9.1 0.8 1.7 0.3 2.0 3.8 9.4 3.0 3.0 1.9 2.6 3.1 1.1 1.4 14.0 2.9 5.8 27.5 5.0 9.2 14.0 6.5 1.5 0.5 48.3 7.1 1.2 6.7 0.9 1.5 1.8 0.1 0.0 2.9 0.5 8.2 52.3 5.1 10.0 0.5 1.4 113.0 2.8 2.9 0.9 1.0 0.6 8.6 23.2 0.3 0.5 2.7 0.3 0.1 0.6 1.1 2.2 2.2 1.6 42.7 2.8 0.4 3.2 2.4 1.3 25.4 1.1 0.8 0.3 6.1 0.4 0.2 0.6 1.3 0.2 0.4 0.2 0.5 1.8 0.8 0.4 0.7 0.8 0.7 0.1 14.1 3.9 22.0 2.3 0.2 1.1 75.5 80.2 88.4 41.3 2.8 3.1 2.6 28.3 0.5 3.1 51.5 2.7 29.3 4.4 4.0 20.9 33.0 2.3 3.3 4.3 1.7 94.9 3.4 7.2 14.4 6.1 5.9 15.5 10.6 5.8 15.4 8.0 9.1 9.4 5.8 14.0 6.7 2.7 0.0 7.0 0.7 225.5 7.8 8.3 14.1 4.6 63.5 7.2 7.6 3.7 2.8 3.2 0.0 6.2 0.9 29.3 2.8 0.0 1.4 15.2 4.0 1.1 7.3 9.5 10.7 19.7 2.8 0.8 2.7 1.5 8.5 6.3 0.5 4.2 1.1 49.5 1.7 10.0 1.6 4.1 119.6 104.4 9.8 0.9 105.0 8.8 32.8 137.6 1.9 37.0 4.5 1.0 3.5 0.1 0.4 96.7 3.8 2.8 0.4 2.4 6.6 0.0 1.7 5.0 75.1 28.8 13.3 8.8 3.7 31.7 0.6 1.0 5.0 PPA1 "IOPPP, PP, PP1, Ppase, SID6-8061" ENSG00000180817 "Inorganic pyrophosphatase 1" Q15181 10 70202835-70233911 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Muller glia cells: 1239.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019878, HPA020096" Supported Supported Vesicles NA NA 1000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 5: Muller glia cells - Visual perception" Vesicles "HPA019878: AB_1855601, HPA020096: AB_1855600" "unprognostic (1.50e-1)" "unprognostic (2.85e-1)" "unprognostic (4.71e-2)" "unprognostic (2.85e-1)" "unprognostic (1.42e-1)" "unprognostic (4.47e-2)" "unprognostic (2.86e-2)" "unprognostic (9.43e-2)" "unprognostic (3.34e-1)" "unprognostic (1.62e-1)" "unprognostic (2.13e-2)" "unprognostic (3.60e-2)" "unprognostic (1.82e-3)" "unprognostic (5.36e-2)" "unprognostic (2.37e-1)" "unprognostic (3.53e-2)" "unprognostic (2.74e-1)" 176.7 198.5 124.3 116.0 138.8 85.0 186.7 166.7 163.0 96.5 123.0 137.3 99.4 85.8 166.7 157.7 110.2 90.3 100.1 125.8 148.5 123.2 150.2 129.0 132.6 153.1 142.3 56.5 188.5 68.5 92.1 103.7 165.4 68.7 152.5 332.0 116.1 78.7 133.0 85.9 125.1 96.8 159.3 64.2 97.5 73.5 141.6 103.5 126.3 137.3 137.3 167.1 140.0 167.0 446.9 181.2 158.8 471.2 421.6 368.8 148.2 163.5 305.3 250.1 261.8 556.7 230.6 641.0 144.5 164.0 162.8 351.2 470.7 318.4 253.8 599.1 443.5 176.1 169.1 321.7 265.8 439.0 106.9 244.2 372.9 201.3 530.7 273.8 307.9 319.2 416.9 336.4 239.4 262.3 426.5 408.7 165.9 614.2 494.8 256.9 181.7 378.2 527.0 276.3 474.4 159.6 179.3 694.5 148.0 110.8 174.3 194.2 141.0 69.0 262.2 229.4 315.2 110.1 259.2 469.8 106.7 605.2 62.0 0.4 68.8 1.7 48.9 55.2 131.1 83.6 112.3 85.6 190.0 59.4 122.7 106.8 4.1 65.8 63.1 44.4 120.4 105.3 124.3 138.8 166.7 163.0 125.8 148.5 153.1 142.3 165.4 159.3 141.6 167.0 207.0 224.4 165.9 17.0 122.7 267.9 366.2 427.3 158.2 184.9 347.8 363.7 93.3 218.8 275.7 108.5 173.0 313.2 63.4 203.3 201.5 540.1 31.7 278.8 196.1 182.1 162.7 88.4 36.8 776.1 298.3 156.9 114.2 512.1 36.8 208.2 38.2 141.8 96.5 85.8 41.2 254.9 160.7 80.1 148.1 31.7 109.6 120.3 181.5 29.0 612.7 1239.0 65.9 21.6 98.4 532.9 213.5 117.4 161.2 512.4 444.5 551.2 92.1 278.4 65.7 97.2 136.8 173.7 170.7 245.8 257.1 245.7 120.9 203.0 347.6 613.9 PPARG "NR1C3, PPARG1, PPARG2, PPARgamma" ENSG00000132170 "Peroxisome proliferator activated receptor gamma" P37231 3 12287368-12434356 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Cancer-related genes, Diabetes mellitus, Disease variant, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 165.1" "Cell type enhanced" "Detected in many" "Adipocytes: 284.1;Extravillous trophoblasts: 217.8;Granulosa cells: 232.9;Urothelial cells: 239.6" "Cancer enhanced" "Detected in all" "urothelial cancer: 33.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 198.7;ASC TERT1: 113.7;BEWO: 247.5;CAPAN-2: 111.6;HSkMC: 118.9;PC-3: 112.0;RT4: 157.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB004282, HPA051239, HPA063663" Approved Enhanced Nucleoplasm,Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Vesicles" "CAB004282: AB_628115, HPA051239: AB_2681400, HPA063663: AB_2685081" "unprognostic (7.35e-3)" "unprognostic (3.27e-2)" "unprognostic (4.05e-2)" "unprognostic (8.37e-2)" "unprognostic (2.41e-2)" "unprognostic (5.27e-3)" "prognostic unfavorable (3.41e-5)" "unprognostic (9.13e-2)" "unprognostic (2.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.02e-2)" "unprognostic (2.77e-1)" "prognostic favorable (1.59e-8)" "unprognostic (1.51e-2)" "unprognostic (1.46e-1)" "unprognostic (9.68e-3)" "prognostic favorable (5.52e-5)" 165.1 3.9 4.0 8.7 3.0 3.0 74.3 3.2 4.7 9.7 0.6 48.7 23.6 7.0 1.2 6.2 7.0 10.5 14.6 4.0 2.7 14.3 17.1 28.5 4.9 3.7 3.5 14.5 2.8 7.9 0.5 43.6 3.4 5.5 40.6 1.0 5.7 1.7 5.2 6.2 15.1 8.7 3.2 12.0 35.5 6.9 3.5 4.1 13.2 8.1 2.1 67.7 9.1 5.0 44.0 38.6 0.0 0.2 198.7 113.7 247.5 3.7 44.7 5.4 2.1 7.8 111.6 0.0 0.1 4.0 72.9 17.3 14.4 0.7 1.0 106.4 20.3 0.0 8.1 10.3 51.8 0.2 0.1 118.9 9.7 9.8 37.5 20.6 0.7 1.0 0.0 0.0 8.3 11.0 0.1 0.8 0.7 99.2 112.0 0.0 0.0 0.2 30.6 157.5 0.1 1.2 18.8 6.7 2.2 6.7 0.0 34.2 35.0 7.8 10.6 4.6 0.2 0.0 0.1 0.3 3.2 0.5 1.2 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.0 3.0 3.2 4.7 4.0 2.7 3.7 3.5 3.4 3.2 3.5 5.0 284.1 3.2 7.2 1.6 0.6 1.0 50.5 0.4 4.6 0.9 1.9 2.8 9.2 1.5 2.5 5.5 0.0 110.4 1.8 93.4 1.9 1.1 4.9 5.2 1.4 26.1 8.4 0.0 39.3 0.7 217.8 12.3 83.1 20.8 8.9 232.9 25.7 3.4 49.9 0.0 74.1 21.3 0.0 19.4 4.8 2.2 4.1 19.1 3.6 38.4 1.8 0.6 0.0 6.6 1.2 17.3 84.1 0.0 1.6 42.1 17.0 14.3 1.5 0.2 13.1 1.9 31.3 10.9 22.8 4.6 1.1 88.9 2.2 0.8 24.5 239.6 PPFIA3 "KIAA0654, LPNA3, MGC126567, MGC126569" ENSG00000177380 "PTPRF interacting protein alpha 3" O75145 19 49119544-49151026 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.6;pituitary gland: 45.0;skin 1: 42.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 40.8;Horizontal cells: 43.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 23.1;PC-3: 36.1;SK-BR-3: 29.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043567, HPA050340" Enhanced Uncertain "Nucleoli fibrillar center,Vesicles" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "Nucleoli fibrillar center, Vesicles" "HPA043567: AB_2678558, HPA050340: AB_2681096" "prognostic unfavorable (3.09e-4)" "unprognostic (4.70e-2)" "unprognostic (5.14e-3)" "prognostic favorable (8.65e-4)" "unprognostic (3.46e-1)" "prognostic favorable (6.46e-7)" "prognostic unfavorable (2.24e-5)" "unprognostic (1.27e-1)" "unprognostic (8.36e-2)" "unprognostic (9.41e-3)" "unprognostic (5.21e-3)" "unprognostic (8.52e-2)" "unprognostic (1.00e-2)" "unprognostic (1.22e-2)" "unprognostic (1.52e-1)" "unprognostic (3.92e-2)" "unprognostic (1.32e-1)" 2.0 4.5 16.4 0.8 18.8 0.2 2.7 11.7 28.6 4.6 0.0 6.6 3.0 2.2 0.3 14.1 1.9 0.6 3.1 18.2 11.4 3.1 2.7 2.9 0.8 10.1 8.7 1.3 4.7 2.1 45.0 0.4 9.9 5.6 1.0 3.7 5.3 0.6 1.4 42.3 3.7 0.4 3.5 2.2 2.4 4.2 11.7 2.4 2.8 0.2 1.1 1.4 8.1 16.6 3.3 3.3 3.3 8.0 0.1 0.0 6.0 0.4 0.4 1.5 2.2 2.2 1.3 7.3 4.3 0.4 2.4 1.7 5.0 0.7 0.4 7.9 10.8 4.6 3.5 1.7 0.4 1.9 11.4 0.4 1.8 1.0 0.5 0.7 0.0 12.1 9.0 11.2 0.1 14.2 2.3 3.2 1.4 23.1 36.1 7.6 6.5 3.6 0.5 1.6 7.2 9.5 1.3 29.7 3.3 0.0 16.5 4.4 0.7 1.7 6.1 1.1 0.2 21.0 18.2 5.4 1.7 7.3 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.4 18.8 11.7 28.6 18.2 11.4 10.1 8.7 9.9 3.5 11.7 16.6 15.7 0.0 0.6 8.5 0.8 7.1 8.0 3.5 11.4 40.8 10.4 6.1 4.2 8.6 3.0 5.5 14.6 0.5 3.6 19.3 19.6 2.7 1.2 1.3 3.6 15.2 26.5 2.7 19.9 4.4 2.1 3.4 3.6 2.4 0.0 2.7 23.2 8.6 2.5 43.7 21.5 26.3 8.2 2.2 2.4 1.7 5.6 2.7 16.0 2.8 0.0 16.2 0.0 10.6 2.7 1.9 13.7 3.8 1.2 18.2 15.0 4.6 0.9 17.9 0.0 0.6 5.5 2.5 5.9 8.7 11.8 0.5 0.7 13.2 20.4 6.3 PPIP5K2 "CFAP160, DFNB100, HISPPD1, KIAA0433, VIP2" ENSG00000145725 "Diphosphoinositol pentakisphosphate kinase 2" O43314 5 103120149-103212799 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hearing "Kinase, Transferase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 160.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037895, HPA038442" Approved Approved Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA037895: AB_2675724, HPA038442: AB_10673173" "unprognostic (2.18e-1)" "unprognostic (1.04e-1)" "unprognostic (2.36e-2)" "unprognostic (1.93e-1)" "unprognostic (8.83e-2)" "unprognostic (1.60e-3)" "unprognostic (1.13e-1)" "unprognostic (2.43e-1)" "unprognostic (1.60e-2)" "unprognostic (8.59e-3)" "unprognostic (1.39e-1)" "unprognostic (2.12e-1)" "unprognostic (4.32e-2)" "unprognostic (1.29e-1)" "unprognostic (4.06e-1)" "prognostic unfavorable (1.12e-4)" "unprognostic (8.80e-2)" 15.7 19.1 6.8 22.0 7.9 51.6 25.1 18.9 13.9 22.2 5.8 28.1 18.3 20.6 21.2 17.1 14.5 20.4 19.5 6.7 8.9 20.3 29.2 16.2 25.5 15.4 11.9 26.1 26.7 23.0 18.1 16.7 15.1 16.3 25.5 19.2 17.1 15.4 4.2 17.2 16.5 18.4 6.1 23.9 22.5 15.1 7.3 27.9 23.3 7.7 24.5 17.8 13.9 10.7 27.4 25.3 50.8 65.2 40.8 53.4 47.8 63.5 39.3 34.2 47.6 20.9 48.3 67.6 56.2 60.9 52.7 16.5 43.9 33.2 57.5 53.7 23.5 84.7 44.3 33.4 29.0 72.1 70.4 34.5 23.4 52.0 46.1 31.2 40.0 42.5 84.9 57.0 53.1 21.3 60.9 44.6 55.4 12.7 64.4 58.6 46.7 89.3 36.8 31.5 29.6 40.1 43.5 39.9 40.7 34.0 33.5 48.9 42.7 55.8 25.7 56.0 45.1 38.1 87.3 91.3 31.5 116.0 51.2 41.7 21.5 39.6 13.0 22.9 15.8 19.5 12.6 14.2 25.6 16.1 16.1 17.0 19.7 17.8 32.4 15.5 12.3 11.1 6.8 7.9 18.9 13.9 6.7 8.9 15.4 11.9 15.1 6.1 7.3 10.7 35.8 48.1 23.1 49.3 39.3 13.6 12.8 13.7 31.9 38.5 26.1 26.4 48.9 18.6 29.6 16.5 45.9 12.7 35.7 29.7 5.9 11.6 5.6 25.4 44.7 28.7 16.3 70.7 88.4 17.0 19.2 33.0 33.6 30.6 43.6 49.2 14.6 20.6 30.6 16.8 160.3 24.2 16.2 39.5 22.4 6.7 29.5 43.3 12.4 49.6 47.5 14.5 27.8 62.8 67.0 16.9 19.1 23.7 56.6 12.1 13.3 22.6 25.1 25.2 6.6 30.3 28.1 39.7 21.6 31.6 15.8 26.0 31.6 38.7 30.1 12.6 PPM1J "DKFZp434P1514, FLJ35951, MGC19531, PP2Czeta, PPP2CZ" ENSG00000155367 "Protein phosphatase, Mg2+/Mn2+ dependent 1J" Q5JR12 1 112709994-112715477 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "epididymis: 18.8;skeletal muscle: 68.4;skin 1: 18.1;testis: 63.8;tongue: 25.6" "Group enriched" "Detected in many" 4 "Early spermatids: 123.6;Late spermatids: 281.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 67.9" "Lineage enriched" "Detected in many" 15 "dendritic cells: 67.9" "Cell line enhanced" "Detected in many" "T-47d: 19.5" "Region enriched" "Detected in many" 7 "olfactory bulb: 27.3" "Low region specificity" "Detected in all" HPA046045 Uncertain Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 6: T47d - Mammary gland" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA046045: AB_2679516" "unprognostic (8.68e-2)" "unprognostic (5.65e-2)" "unprognostic (3.29e-2)" "unprognostic (2.59e-1)" "unprognostic (2.93e-3)" "unprognostic (2.34e-2)" "unprognostic (3.55e-2)" "unprognostic (3.74e-2)" "unprognostic (2.55e-1)" "unprognostic (9.30e-3)" "unprognostic (3.36e-2)" "unprognostic (7.22e-2)" "unprognostic (1.80e-2)" "unprognostic (1.27e-2)" "unprognostic (1.46e-1)" "unprognostic (2.28e-2)" "unprognostic (9.96e-4)" 1.1 2.6 6.3 1.0 6.6 0.7 2.2 5.9 6.5 2.3 3.8 1.2 0.6 1.9 18.8 4.6 2.8 1.0 8.7 5.8 5.7 7.8 0.7 1.6 3.3 5.2 7.8 2.3 1.7 5.5 2.6 0.5 4.6 3.3 0.6 6.9 2.8 2.1 68.4 18.1 1.4 1.3 4.5 1.4 1.2 63.8 9.1 2.3 3.1 25.6 2.2 1.1 4.0 3.9 2.7 0.1 1.5 1.7 0.8 1.5 1.1 0.3 0.7 0.3 1.0 1.2 0.8 0.4 0.4 0.8 0.8 4.9 1.1 4.6 0.4 0.0 2.6 0.8 0.2 0.2 0.9 0.0 0.2 1.7 3.0 0.9 4.6 1.0 2.1 0.2 1.0 0.0 1.2 2.9 0.0 0.0 1.6 1.4 2.3 0.1 0.1 0.0 2.7 0.1 0.8 0.2 0.6 4.3 1.3 2.2 19.5 0.0 1.1 0.3 2.8 0.0 0.2 0.1 0.0 0.0 2.3 0.6 2.6 0.0 0.3 0.0 0.0 1.5 0.1 0.7 0.0 0.1 7.1 0.7 0.0 0.0 0.0 0.0 4.3 67.9 0.0 0.8 6.3 6.6 5.9 6.5 5.8 5.7 5.2 7.8 4.6 4.5 9.1 3.9 1.2 0.0 0.5 0.3 2.0 2.2 4.7 8.7 10.2 5.7 4.2 4.6 5.8 0.0 2.7 1.8 10.4 1.0 41.3 0.7 9.8 3.2 123.6 3.2 0.3 1.5 0.0 0.0 1.8 4.3 1.4 1.1 1.1 0.6 0.0 5.6 0.7 0.1 0.7 0.0 1.5 0.9 2.0 1.3 11.5 281.6 3.1 2.0 0.0 0.0 1.6 25.4 0.0 0.0 0.2 2.1 2.4 2.6 0.0 6.7 0.3 0.6 1.8 9.1 6.6 1.1 2.8 2.8 16.9 3.5 2.8 0.5 0.9 3.2 0.8 2.9 PPM1N FLJ40125 ENSG00000213889 "Protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)" Q8N819 19 45488777-45502510 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 8 "skeletal muscle: 213.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 123.1;Rod photoreceptor cells: 74.3" "Cancer enhanced" "Detected in many" "testis cancer: 11.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "non-classical monocyte: 142.4" "Lineage enriched" "Detected in all" 11 "monocytes: 142.4" "Cell line enhanced" "Detected in many" "OE19: 24.1;RT4: 29.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043577 Supported Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "HPA043577: " "unprognostic (2.38e-2)" "unprognostic (1.11e-2)" "unprognostic (8.53e-2)" "unprognostic (6.59e-2)" "unprognostic (4.71e-1)" "unprognostic (2.64e-2)" "unprognostic (1.98e-3)" "unprognostic (1.02e-1)" "unprognostic (1.25e-1)" "unprognostic (4.45e-2)" "unprognostic (9.27e-2)" "unprognostic (2.48e-2)" "unprognostic (1.11e-16)" "unprognostic (3.42e-2)" "unprognostic (1.79e-1)" "unprognostic (3.92e-2)" "unprognostic (1.86e-3)" 2.0 0.8 15.5 2.0 14.7 2.6 3.3 14.5 19.9 2.0 14.5 2.6 0.6 0.7 1.3 2.6 0.9 1.4 1.3 15.1 15.0 1.4 2.6 2.5 3.0 14.7 14.7 0.6 0.5 2.1 1.1 4.7 15.1 1.2 1.3 25.8 0.9 2.0 213.3 3.1 1.6 1.2 13.7 9.2 2.8 5.3 14.3 2.3 1.1 0.2 3.4 2.4 1.6 16.2 2.6 7.1 1.2 5.1 5.9 7.8 14.7 1.9 3.0 0.6 2.3 1.7 15.8 11.1 3.2 1.8 4.1 7.6 3.0 2.2 0.9 10.9 4.5 9.0 2.7 1.9 1.4 0.8 18.1 3.2 3.6 3.1 1.9 4.0 1.0 4.4 10.3 9.6 1.0 1.9 3.1 4.6 4.0 24.1 1.4 2.0 1.5 3.0 3.4 29.9 5.8 6.8 1.0 11.1 9.2 8.8 3.8 2.7 1.5 8.2 4.7 4.3 1.4 1.7 4.5 2.3 6.1 2.3 7.2 6.7 4.4 3.2 6.4 22.5 5.5 6.3 3.9 6.2 12.8 3.6 4.3 7.9 6.5 3.1 142.4 2.4 4.5 5.7 15.5 14.7 14.5 19.9 15.1 15.0 14.7 14.7 15.1 13.7 14.3 16.2 6.4 0.0 2.7 1.0 7.5 3.4 14.7 6.2 17.6 14.1 5.9 32.5 2.3 17.2 2.5 3.7 31.3 3.2 6.0 5.5 0.0 2.9 12.5 2.0 3.9 3.5 3.0 0.8 1.1 1.8 123.1 6.5 3.1 7.4 7.0 1.0 5.3 1.3 20.1 1.7 1.4 4.2 0.0 15.5 15.7 4.9 0.9 15.2 1.8 1.0 6.1 7.3 20.6 0.0 0.3 3.1 4.7 0.7 1.7 6.7 6.9 0.6 0.8 74.3 0.0 25.6 5.5 2.9 9.1 3.4 4.1 8.5 7.5 0.3 3.1 8.4 PPOX "PPO, VP" ENSG00000143224 "Protoporphyrinogen oxidase" P50336 1 161166056-161178013 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 65.9;Respiratory ciliated cells: 84.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030123 Uncertain Approved Vesicles,Mitochondria,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Mitochondria "Vesicles, Cytosol" "HPA030123: AB_10603987" "unprognostic (1.17e-1)" "unprognostic (4.73e-2)" "unprognostic (9.88e-2)" "unprognostic (2.13e-2)" "unprognostic (3.24e-1)" "unprognostic (1.64e-2)" "unprognostic (9.58e-3)" "unprognostic (1.79e-2)" "unprognostic (9.17e-2)" "unprognostic (1.17e-1)" "unprognostic (2.18e-3)" "unprognostic (7.12e-3)" "prognostic unfavorable (9.89e-4)" "unprognostic (6.12e-2)" "unprognostic (2.23e-1)" "unprognostic (3.27e-1)" "unprognostic (1.80e-2)" 9.3 17.1 24.2 3.5 24.5 25.2 10.3 25.2 38.2 14.5 24.7 12.7 3.9 10.9 8.3 8.9 22.0 4.7 13.1 24.4 24.7 15.5 11.5 8.6 5.7 25.0 25.0 13.8 10.8 7.2 13.7 6.5 24.6 13.4 3.9 12.6 8.7 7.7 7.6 11.2 8.5 6.6 25.0 13.6 10.9 6.9 24.0 5.0 11.9 5.6 5.2 11.6 9.6 25.4 10.0 8.0 12.7 8.5 10.4 9.3 3.5 5.9 5.7 7.5 10.3 10.4 9.3 7.4 14.3 5.3 4.1 6.3 9.8 8.8 7.1 4.6 20.3 9.0 18.9 23.9 8.6 3.0 4.6 7.6 11.0 6.3 9.4 9.4 14.7 7.0 22.8 11.2 5.6 9.2 12.0 8.6 8.2 11.2 18.8 13.6 8.2 16.7 15.1 4.2 9.8 14.7 6.6 10.3 12.0 14.6 19.9 9.5 5.7 6.5 7.1 6.5 7.5 19.4 15.3 10.5 6.8 6.0 4.9 6.3 7.2 5.3 10.4 7.6 7.2 9.0 7.8 7.6 10.4 8.2 6.8 6.9 2.9 12.0 5.2 6.6 16.1 7.8 24.2 24.5 25.2 38.2 24.4 24.7 25.0 25.0 24.6 25.0 24.0 25.4 10.9 3.2 13.7 10.4 9.8 12.0 8.3 16.6 9.1 18.0 12.1 14.1 10.1 4.3 15.6 7.3 22.9 21.4 10.6 3.6 21.5 9.5 9.8 39.1 5.9 8.3 6.0 65.9 5.9 5.6 9.4 9.1 5.1 4.6 6.3 12.3 8.9 6.1 9.3 15.2 7.5 7.3 26.4 4.7 8.4 12.1 10.2 8.0 1.8 5.6 8.1 10.4 8.2 9.0 8.9 6.3 3.8 6.8 16.9 3.2 6.6 17.2 84.4 20.9 6.6 9.6 15.6 12.8 9.3 7.2 14.9 10.4 10.6 11.1 7.5 6.2 PPP1R11 "CFAP255, HCG-V, HCGV, TCTE5, Tctex5" ENSG00000204619 "Protein phosphatase 1 regulatory inhibitor subunit 11" O60927 6 30066709-30070333 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Protein phosphatase inhibitor, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Late spermatids: 696.0" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in some" 8 "cerebral cortex: 8.8" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 51.5;AN3-CA: 65.6;fHDF/TERT166: 48.6;GAMG: 47.4;HBEC3-KT: 53.6;JURKAT: 76.7;RPTEC TERT1: 47.4;U-266/84: 64.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043266, HPA060174" Approved Approved Vesicles NA NA 43000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA043266: AB_2678400, HPA060174: AB_2684216" "unprognostic (2.00e-2)" "unprognostic (1.10e-1)" "unprognostic (8.88e-2)" "unprognostic (4.24e-2)" "unprognostic (3.45e-1)" "unprognostic (1.05e-1)" "unprognostic (1.77e-2)" "unprognostic (1.18e-1)" "unprognostic (2.81e-1)" "unprognostic (1.74e-3)" "unprognostic (3.33e-2)" "unprognostic (2.68e-1)" "unprognostic (8.36e-3)" "unprognostic (1.74e-1)" "unprognostic (3.31e-1)" "unprognostic (2.21e-1)" "unprognostic (4.69e-3)" 44.5 41.1 0.7 0.0 0.7 1.9 41.4 0.6 8.8 44.4 0.6 55.5 11.6 49.6 33.1 52.1 37.3 11.8 51.0 0.7 0.7 62.3 47.5 43.7 5.4 0.9 0.7 41.8 45.1 2.2 29.2 5.8 0.8 46.3 0.7 7.9 42.8 0.0 50.4 42.9 50.7 0.0 0.6 39.8 59.5 41.5 0.7 9.7 42.3 0.0 11.8 51.6 42.7 1.1 51.5 0.0 0.0 65.6 29.4 26.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 48.6 47.4 0.0 0.0 53.6 0.0 1.0 34.5 42.6 0.0 0.0 0.0 3.0 3.9 0.0 0.0 0.0 0.7 0.0 0.0 76.7 0.5 2.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.4 47.4 29.0 0.0 0.0 0.7 35.5 4.8 26.8 0.0 0.0 0.0 0.0 0.3 4.1 1.5 30.7 64.9 26.7 0.7 0.0 0.0 11.5 4.1 12.4 4.7 9.3 4.5 6.8 5.3 6.5 2.2 7.2 4.9 7.0 2.8 3.9 7.9 3.2 8.4 6.8 0.7 0.7 0.6 8.8 0.7 0.7 0.9 0.7 0.8 0.6 0.7 1.1 38.2 19.2 20.2 2.6 57.8 52.8 80.0 77.2 29.0 29.3 47.7 32.8 18.8 52.9 49.7 40.5 6.2 56.0 39.2 111.5 95.9 142.2 242.1 19.8 24.2 44.3 53.7 32.4 10.1 136.3 119.9 27.0 53.5 31.8 78.6 21.4 45.7 28.0 65.7 13.5 9.0 83.8 77.3 49.7 53.8 696.0 32.3 43.5 62.2 3.7 75.4 58.4 92.7 6.0 7.6 136.5 114.1 40.3 42.2 66.6 139.6 93.3 38.7 33.1 39.5 27.2 89.4 61.9 23.2 39.0 66.5 75.2 52.4 16.5 51.8 94.9 PPP1R15A GADD34 ENSG00000087074 "Protein phosphatase 1 regulatory subunit 15A" O75807 19 48872421-48876058 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Stress response, Translation regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 575.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 340.1" "Group enriched" "Detected in all" 5 "dendritic cells: 114.6;granulocytes: 340.1" "Cell line enhanced" "Detected in all" "HHSteC: 282.8;hTERT-HME1: 493.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018395, HPA020240" Approved Uncertain Vesicles NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Vesicles "CAB018395: AB_2237473, HPA020240: AB_1849404" "unprognostic (2.43e-3)" "unprognostic (3.21e-1)" "unprognostic (7.75e-2)" "unprognostic (1.17e-3)" "unprognostic (2.22e-2)" "unprognostic (6.17e-2)" "prognostic unfavorable (1.95e-4)" "unprognostic (5.46e-2)" "unprognostic (2.66e-2)" "unprognostic (7.16e-3)" "unprognostic (5.40e-2)" "unprognostic (1.52e-1)" "unprognostic (2.22e-1)" "unprognostic (6.43e-3)" "unprognostic (1.49e-1)" "unprognostic (1.29e-2)" "unprognostic (6.94e-2)" 199.1 84.7 33.3 49.5 37.4 575.6 97.7 45.9 54.1 99.5 66.9 78.9 36.0 70.1 11.3 98.3 147.4 82.0 185.6 34.8 36.2 95.0 85.1 226.7 33.1 44.8 32.7 101.2 33.4 23.1 65.0 74.8 42.9 60.5 45.5 10.9 41.6 38.6 88.5 191.5 58.8 101.8 29.4 69.0 90.7 23.3 38.7 52.0 69.4 60.6 20.2 110.6 108.4 46.9 55.8 23.7 24.9 20.5 71.2 40.4 39.3 95.1 148.0 106.5 95.9 36.5 27.6 19.1 25.0 69.0 145.5 39.4 9.3 49.7 79.8 10.7 14.4 86.4 14.4 18.1 282.8 20.2 119.2 55.1 135.5 147.0 493.7 48.0 56.3 21.5 118.2 155.6 69.5 6.1 11.1 27.9 6.2 100.3 42.3 12.6 23.1 6.5 22.3 63.8 14.2 24.3 49.2 33.2 230.2 26.0 11.9 36.1 60.6 126.3 31.8 89.3 58.5 82.8 72.1 17.9 46.2 13.7 154.8 161.8 49.4 91.3 22.5 31.1 19.6 36.7 22.2 18.7 35.9 29.7 12.3 11.0 340.1 13.8 37.6 114.6 31.5 36.9 33.3 37.4 45.9 54.1 34.8 36.2 44.8 32.7 42.9 29.4 38.7 46.9 499.1 288.4 225.1 2.3 387.2 482.2 989.5 232.0 730.1 25.0 294.3 220.7 173.3 127.2 204.3 12.9 35.5 104.8 290.3 435.6 3.9 224.0 4.6 619.6 427.4 370.4 170.9 213.5 4.1 94.5 219.0 466.3 430.7 1063.2 708.1 53.3 150.0 14.4 195.0 35.3 4.1 354.1 140.4 146.7 904.4 5.1 58.7 615.3 396.6 9.4 105.1 50.5 20.6 1.0 2.0 233.4 421.8 23.0 477.1 731.5 348.7 9.0 246.2 27.7 85.5 483.5 612.1 7.0 9.5 573.1 431.0 288.4 427.9 102.8 321.8 733.9 PPP1R21 "CCDC128, FLJ16566, KLRAQ1" ENSG00000162869 "Protein phosphatase 1 regulatory subunit 21" Q6ZMI0 2 48440598-48515391 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 99.6;Oligodendrocytes: 190.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036791, HPA036792" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 34: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Nucleoplasm "HPA036791: AB_10671713, HPA036792: AB_2675317" "unprognostic (1.25e-1)" "unprognostic (2.13e-1)" "unprognostic (2.51e-1)" "prognostic unfavorable (6.83e-4)" "unprognostic (1.57e-2)" "unprognostic (1.01e-1)" "unprognostic (2.78e-3)" "unprognostic (1.44e-2)" "unprognostic (7.46e-2)" "unprognostic (3.00e-1)" "prognostic favorable (8.05e-4)" "unprognostic (1.13e-1)" "prognostic favorable (4.59e-6)" "unprognostic (9.23e-2)" "unprognostic (1.93e-1)" "prognostic favorable (9.87e-4)" "unprognostic (6.60e-2)" 9.3 10.6 10.6 10.5 13.4 9.9 8.5 8.2 13.4 8.5 10.7 8.8 7.9 12.7 19.6 12.1 14.5 10.8 10.1 9.7 9.4 28.1 11.6 11.2 13.3 11.1 11.0 13.4 8.1 33.5 9.6 12.8 10.2 11.4 10.6 12.0 5.7 10.6 5.7 10.5 9.9 13.0 8.7 13.0 9.0 9.4 11.7 13.9 21.4 4.8 12.2 9.5 7.6 18.9 17.3 8.2 6.8 8.5 17.1 12.5 18.3 10.0 11.0 6.1 7.2 4.5 10.6 11.8 16.4 14.2 11.7 9.3 5.8 9.1 12.4 15.1 4.8 12.6 7.2 10.8 11.6 5.5 9.8 15.9 8.1 11.0 13.2 15.1 15.3 5.9 5.2 19.2 16.7 9.5 10.9 9.5 17.7 12.3 8.4 9.1 18.8 13.1 11.9 10.8 9.2 5.7 19.0 4.8 18.1 18.2 8.6 9.0 13.9 6.4 7.8 5.6 8.0 14.3 4.1 10.5 10.2 12.5 8.6 18.6 4.7 8.1 3.7 5.4 2.9 5.4 4.3 4.4 5.0 6.8 6.4 5.5 11.6 3.8 4.8 3.1 4.6 2.3 10.6 13.4 8.2 13.4 9.7 9.4 11.1 11.0 10.2 8.7 11.7 18.9 14.5 22.4 16.5 37.5 23.6 10.5 32.9 8.6 13.6 9.1 6.9 6.7 11.0 14.3 9.2 25.8 2.1 21.7 8.5 11.7 5.9 11.0 3.9 10.2 11.5 10.9 18.7 10.3 99.6 8.4 16.3 15.0 25.5 12.3 12.0 12.4 10.8 13.6 35.2 28.6 49.6 10.7 10.2 26.1 12.2 5.7 12.2 19.3 12.4 44.0 24.3 21.2 19.6 69.9 190.3 12.2 9.3 20.7 19.4 17.0 10.7 59.3 20.0 6.8 13.1 9.6 14.2 9.8 10.8 17.4 14.1 27.1 20.5 12.1 8.4 27.2 PPP1R3D PPP1R6 ENSG00000132825 "Protein phosphatase 1 regulatory subunit 3D" O95685 20 59936663-59940305 "Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.0" "Group enriched" "Detected in many" 4 "granulocytes: 3.0;monocytes: 1.8" "Cell line enhanced" "Detected in many" "SK-BR-3: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041146 Approved Approved Nucleoli,Vesicles,Mitochondria NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 28: BEWO - Transcription regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Mitochondria" Nucleoli "HPA041146: AB_10793870" "unprognostic (2.50e-3)" "unprognostic (3.55e-3)" "unprognostic (6.90e-2)" "unprognostic (1.23e-1)" "unprognostic (7.23e-2)" "unprognostic (5.87e-2)" "unprognostic (5.73e-2)" "unprognostic (2.39e-3)" "unprognostic (5.54e-2)" "unprognostic (3.27e-1)" "unprognostic (3.52e-2)" "unprognostic (1.20e-1)" "unprognostic (1.48e-2)" "prognostic favorable (9.14e-4)" "unprognostic (4.71e-2)" "unprognostic (1.47e-2)" "unprognostic (5.71e-2)" 3.7 2.9 6.7 4.8 7.3 6.3 3.8 7.3 7.4 4.2 4.6 3.7 5.3 3.7 3.4 5.8 3.5 3.0 5.5 5.9 6.6 4.1 1.1 3.5 3.9 7.6 6.9 4.5 3.5 5.1 2.8 5.4 7.1 6.3 3.0 2.1 4.3 5.6 7.1 4.2 5.0 3.8 7.0 4.9 5.4 1.9 6.8 3.3 3.6 9.8 5.1 3.4 3.6 6.7 5.1 3.1 2.1 4.3 4.6 4.8 17.3 6.6 7.1 7.9 3.8 4.9 6.8 2.1 8.0 5.5 4.9 14.7 4.3 4.7 5.1 5.0 3.4 5.6 4.2 2.6 4.2 2.3 15.2 3.4 12.7 2.8 2.4 4.2 4.4 1.4 1.0 0.5 5.1 7.9 1.9 7.5 1.5 9.6 7.3 2.4 0.9 3.3 5.3 8.1 4.0 2.4 8.2 24.6 7.4 3.9 9.0 8.2 4.7 4.6 1.9 4.9 1.1 1.7 4.5 0.5 3.5 8.1 2.9 0.3 0.7 3.0 0.4 0.3 0.3 0.3 0.3 0.3 0.5 0.2 0.3 0.2 1.8 0.4 1.8 0.2 0.4 0.2 6.7 7.3 7.3 7.4 5.9 6.6 7.6 6.9 7.1 7.0 6.8 6.7 10.4 9.6 0.5 12.4 3.3 1.3 4.6 2.6 4.6 7.8 5.7 4.2 6.7 7.2 4.3 5.5 2.1 14.3 4.5 4.0 5.9 1.9 0.4 3.0 4.9 8.6 1.8 1.3 0.9 3.1 6.4 3.3 3.1 3.4 5.7 3.9 9.7 0.4 5.2 13.5 2.4 3.6 0.0 9.8 2.6 1.3 3.1 7.4 5.4 1.0 8.7 11.0 13.4 2.5 1.8 3.5 6.1 4.5 3.7 6.7 6.7 6.2 4.3 11.4 6.6 5.7 4.9 0.4 3.6 4.7 3.1 4.9 5.6 5.1 3.8 9.5 PPP1R3F Hb2E ENSG00000049769 "Protein phosphatase 1 regulatory subunit 3F" Q6ZSY5 X 49269793-49301461 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 27.5" "Cell type enhanced" "Detected in many" "Bipolar cells: 38.6;Horizontal cells: 48.8;Oligodendrocytes: 34.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "T-reg: 9.4" "Lineage enriched" "Detected in single" 12 "T-cells: 9.4" "Cell line enhanced" "Detected in many" "GAMG: 13.6;HDLM-2: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000244, HPA000918" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Vesicles" "HPA000244: AB_2665949, HPA000918: AB_2268692" "unprognostic (6.69e-2)" "unprognostic (2.87e-2)" "unprognostic (4.98e-4)" "unprognostic (1.83e-2)" "unprognostic (6.48e-2)" "unprognostic (4.93e-2)" "unprognostic (1.26e-1)" "unprognostic (5.17e-2)" "unprognostic (1.91e-2)" "unprognostic (2.89e-1)" "prognostic favorable (1.85e-6)" "unprognostic (5.99e-2)" "unprognostic (1.50e-1)" "unprognostic (1.43e-1)" "unprognostic (2.76e-1)" "unprognostic (7.96e-2)" "unprognostic (1.55e-1)" 3.1 4.0 13.9 2.4 14.9 1.5 3.2 14.0 18.3 5.7 8.1 7.4 1.3 5.8 5.8 4.2 7.1 1.5 18.1 15.2 14.1 4.1 3.4 3.3 2.7 14.7 13.5 8.2 2.6 1.1 15.5 1.0 17.2 5.6 0.6 9.7 3.1 1.4 27.5 3.3 3.5 1.3 12.5 4.0 3.4 4.2 14.1 1.3 5.3 12.8 1.4 6.7 4.6 19.1 2.1 4.7 2.9 3.6 2.4 1.8 2.3 2.8 1.8 1.3 2.2 3.0 1.8 2.2 0.6 0.6 13.6 3.6 0.9 0.5 0.9 13.2 4.4 0.2 4.0 0.3 1.5 0.6 1.5 1.4 1.4 1.5 0.5 2.2 0.1 2.8 0.6 0.9 0.9 6.2 1.2 2.5 9.8 0.1 5.8 6.1 3.2 1.1 1.4 1.1 3.8 3.7 0.9 0.1 6.2 4.5 3.3 2.3 2.5 4.1 1.0 3.0 2.0 3.6 4.4 1.5 1.6 5.2 4.8 0.0 0.2 0.0 0.2 0.3 0.6 0.3 1.8 0.6 0.2 0.0 1.5 0.6 0.0 0.3 0.7 0.2 9.4 0.3 13.9 14.9 14.0 18.3 15.2 14.1 14.7 13.5 17.2 12.5 14.1 19.1 2.1 0.0 0.5 14.0 2.8 1.9 2.4 1.0 4.0 38.6 2.5 3.4 16.8 0.0 0.7 3.7 8.4 1.1 1.7 0.3 7.9 0.3 0.1 3.6 2.8 2.2 3.0 0.8 9.6 0.2 0.1 3.8 0.0 2.0 0.0 4.3 3.3 1.1 0.7 48.8 10.7 0.1 0.0 0.6 1.8 0.7 4.7 1.5 0.0 3.7 0.2 11.9 0.0 12.5 34.3 0.4 0.1 3.0 2.0 2.2 0.0 7.6 2.6 17.8 0.0 4.0 3.9 2.0 8.5 7.3 1.3 1.2 5.6 2.4 0.2 2.3 PPP3CC "CALNA3, PP2Bgamma" ENSG00000120910 "Protein phosphatase 3 catalytic subunit gamma" P48454 8 22440819-22541142 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 145.8;Spermatocytes: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023396, CAB024950" Approved Approved Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Vesicles "CAB024950: , HPA023396: AB_1855663" "unprognostic (7.66e-3)" "unprognostic (1.61e-2)" "unprognostic (1.55e-1)" "unprognostic (1.01e-1)" "unprognostic (1.38e-1)" "unprognostic (2.21e-2)" "unprognostic (7.71e-2)" "prognostic favorable (6.80e-5)" "unprognostic (9.25e-2)" "unprognostic (1.97e-1)" "unprognostic (8.84e-2)" "unprognostic (4.05e-2)" "unprognostic (7.16e-2)" "unprognostic (2.35e-2)" "unprognostic (4.00e-1)" "unprognostic (2.78e-2)" "unprognostic (1.64e-2)" 28.5 11.9 11.8 16.5 11.8 26.5 20.8 17.7 15.3 18.1 31.1 16.6 9.1 14.5 10.6 16.9 15.6 15.7 34.5 11.3 10.8 12.9 12.4 21.5 33.0 12.1 11.0 14.0 14.3 18.4 11.7 19.3 12.2 14.4 10.3 77.9 14.0 8.2 89.4 13.6 15.4 15.5 10.0 22.4 14.6 56.0 13.1 15.0 16.6 54.2 26.9 17.0 16.4 14.8 12.2 8.8 7.7 9.4 19.8 24.4 11.2 16.5 28.9 23.9 26.5 5.1 7.5 45.7 19.7 25.6 40.0 8.4 17.9 16.5 30.5 26.3 9.5 9.8 10.5 14.7 26.8 7.1 15.6 15.0 22.3 16.2 16.5 25.6 21.1 22.0 19.6 58.8 27.2 5.7 16.8 11.7 5.6 12.5 12.0 54.0 18.1 15.2 22.4 11.3 5.4 12.7 12.3 7.4 17.4 14.4 4.9 11.8 22.8 37.1 7.9 56.7 12.9 29.3 38.5 48.3 19.6 9.3 25.1 5.4 2.7 10.7 16.6 3.2 12.7 26.3 19.0 23.6 5.1 21.3 18.1 14.9 0.6 19.2 4.7 6.2 17.2 7.1 11.8 11.8 17.7 15.3 11.3 10.8 12.1 11.0 12.2 10.0 13.1 14.8 27.2 6.4 5.1 49.6 74.7 16.6 21.3 32.6 12.0 12.8 10.0 6.0 8.0 14.3 14.0 7.3 47.9 18.0 50.3 6.7 7.9 15.0 145.8 6.5 12.7 24.2 10.3 10.8 78.9 21.0 23.8 25.1 6.6 14.6 3.8 3.9 23.6 7.8 13.1 3.3 83.6 2.5 38.7 10.8 24.6 22.6 22.4 19.3 28.4 76.8 30.4 13.1 59.8 99.5 64.8 21.1 7.4 21.4 96.8 26.3 10.6 11.6 7.8 50.5 32.9 19.5 23.3 131.8 29.6 17.1 11.4 14.1 53.4 4.8 6.3 25.5 PPP5C "PP5, PPP5" ENSG00000011485 "Protein phosphatase 5 catalytic subunit" P53041 19 46347087-46392981 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Hydrolase, Protein phosphatase" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022641, HPA029065, HPA056933" Approved Supported Vesicles,Cytosol NA NA 120000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 59: Non-specific - Transcription" "Vesicles, Cytosol" "CAB022641: , HPA029065: AB_10610284, HPA056933: AB_2683278" "unprognostic (8.25e-2)" "unprognostic (7.90e-2)" "unprognostic (1.44e-1)" "unprognostic (6.30e-2)" "unprognostic (5.92e-2)" "unprognostic (2.62e-2)" "prognostic unfavorable (3.45e-6)" "unprognostic (1.29e-1)" "unprognostic (1.04e-2)" "unprognostic (8.25e-2)" "unprognostic (5.56e-2)" "unprognostic (2.20e-2)" "unprognostic (3.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.35e-1)" "unprognostic (5.92e-3)" "unprognostic (1.37e-1)" 27.4 37.5 27.7 17.7 29.3 14.2 26.3 28.4 36.5 28.0 27.7 31.3 16.8 34.9 9.8 30.4 31.7 13.3 56.4 29.8 28.6 29.1 32.7 28.0 19.7 32.3 28.2 24.7 23.7 32.5 36.6 15.8 33.3 23.7 15.4 14.4 23.0 18.2 58.9 27.5 25.9 20.8 26.2 33.5 33.6 16.9 30.3 20.5 26.2 45.7 15.0 27.7 26.3 28.5 61.9 114.9 66.0 50.1 48.3 50.9 30.6 75.4 59.6 88.2 78.2 82.4 47.9 94.3 39.9 54.0 48.4 49.9 86.2 88.5 24.7 65.9 120.5 76.4 80.9 59.4 54.5 106.6 52.8 47.8 40.9 62.1 45.9 34.2 77.2 79.3 76.0 47.3 49.4 67.5 59.5 203.4 50.2 109.6 61.7 89.0 56.6 76.5 52.8 81.8 93.1 69.7 62.6 78.8 26.9 28.6 49.7 67.8 65.5 38.3 64.3 29.1 79.1 38.0 93.0 111.5 41.7 89.4 65.9 0.0 10.3 3.0 27.8 18.0 17.8 15.1 12.8 22.0 16.8 11.7 12.2 16.8 0.2 22.0 23.4 11.7 14.3 15.4 27.7 29.3 28.4 36.5 29.8 28.6 32.3 28.2 33.3 26.2 30.3 28.5 28.1 6.4 12.5 22.9 16.5 9.4 16.6 20.9 19.9 19.7 13.1 13.5 5.6 44.3 14.2 16.5 16.7 26.4 12.3 25.2 33.2 29.9 1.2 31.3 25.2 19.6 14.9 11.6 18.5 19.5 36.2 17.6 26.0 19.6 4.5 18.6 24.3 24.9 21.6 16.8 23.2 17.0 22.4 12.3 8.2 3.2 17.4 11.9 16.0 11.2 12.1 21.0 17.5 17.6 14.5 26.4 17.0 18.4 25.5 12.1 16.3 21.4 14.6 17.9 39.5 14.6 19.9 26.6 32.0 20.8 13.2 25.7 20.4 23.1 25.0 11.7 PPP6R2 "dJ579N16.1, KIAA0685, SAP190, SAPS2" ENSG00000100239 "Protein phosphatase 6 regulatory subunit 2" O75170 22 50343304-50445090 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030656, CAB034919" Uncertain Supported Vesicles,Cytosol NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Vesicles, Cytosol" "CAB034919: AB_2183817, HPA030656: AB_10602926" "unprognostic (1.24e-1)" "unprognostic (1.82e-3)" "unprognostic (1.03e-1)" "prognostic favorable (1.70e-5)" "unprognostic (2.17e-1)" "unprognostic (3.79e-3)" "unprognostic (2.32e-1)" "unprognostic (1.30e-2)" "unprognostic (2.82e-1)" "unprognostic (1.82e-2)" "prognostic favorable (7.51e-4)" "unprognostic (6.89e-2)" "unprognostic (1.42e-2)" "unprognostic (1.20e-2)" "unprognostic (2.13e-1)" "unprognostic (1.02e-1)" "unprognostic (7.77e-3)" 21.9 35.6 23.5 20.9 27.3 21.4 23.2 24.3 32.2 23.7 19.2 28.5 24.5 25.4 11.5 28.3 23.8 18.0 36.7 25.4 19.7 29.6 72.4 25.2 27.3 26.9 22.2 24.8 29.0 21.4 41.0 14.8 21.8 31.4 11.8 12.6 27.9 17.1 65.8 27.6 28.7 14.0 18.2 32.4 30.1 62.7 26.0 25.8 30.8 31.7 16.5 23.9 22.3 25.8 30.9 17.8 27.3 34.8 19.7 21.0 24.4 30.1 31.9 31.5 31.7 15.0 18.7 36.9 14.5 30.0 17.4 24.6 16.9 22.4 11.8 19.3 30.9 19.8 37.7 37.7 25.6 46.9 52.1 31.2 23.8 19.0 10.1 24.8 27.8 30.8 20.5 31.5 23.2 50.0 32.3 33.9 11.3 19.5 21.9 44.8 20.9 24.3 23.1 36.1 17.0 23.1 31.0 47.6 25.0 10.1 17.2 35.2 32.5 29.3 26.4 24.6 20.3 33.6 8.7 32.7 30.6 22.6 41.2 4.0 8.6 5.8 9.0 9.4 10.4 7.9 6.2 9.6 8.8 8.4 5.9 7.9 13.7 5.9 6.8 11.0 13.3 8.5 23.5 27.3 24.3 32.2 25.4 19.7 26.9 22.2 21.8 18.2 26.0 25.8 28.5 22.4 20.6 79.0 32.0 8.8 14.4 12.9 22.8 43.7 25.5 21.8 19.2 37.1 17.1 27.6 56.3 17.3 39.9 39.8 31.3 19.3 84.0 30.8 39.0 18.1 26.9 19.8 83.0 32.5 11.8 15.3 35.2 34.8 31.8 23.9 18.9 65.1 16.0 65.6 80.8 23.0 16.2 25.3 8.8 48.6 19.6 23.4 10.6 61.8 32.1 25.0 50.4 52.8 59.9 33.3 29.0 19.9 42.0 19.4 27.0 23.6 17.9 43.2 26.3 16.9 18.7 78.5 47.1 17.9 8.5 28.5 28.4 17.8 25.2 17.5 PPT1 "CLN1, INCL, PPT" ENSG00000131238 "Palmitoyl-protein thioesterase 1" P50897 1 40072710-40097260 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 251.9;Kupffer cells: 315.8;Langerhans cells: 328.8;Macrophages: 271.3;monocytes: 227.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 1254.3;eosinophil: 624.2;intermediate monocyte: 1006.3;myeloid DC: 1091.1;neutrophil: 683.9;non-classical monocyte: 815.7" "Group enriched" "Detected in all" 4 "dendritic cells: 1091.1;granulocytes: 683.9;monocytes: 1254.3" "Cell line enhanced" "Detected in all" "SK-BR-3: 1082.7;THP-1: 1449.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021546 Supported Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 240000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "HPA021546: AB_1855667" "unprognostic (5.02e-2)" "unprognostic (2.73e-1)" "unprognostic (1.64e-1)" "unprognostic (2.06e-3)" "unprognostic (6.68e-2)" "unprognostic (2.83e-2)" "prognostic unfavorable (6.98e-8)" "unprognostic (1.39e-1)" "unprognostic (1.78e-1)" "unprognostic (1.23e-1)" "unprognostic (8.16e-2)" "unprognostic (2.39e-1)" "unprognostic (5.20e-3)" "unprognostic (1.75e-1)" "unprognostic (2.30e-1)" "unprognostic (2.93e-2)" "unprognostic (2.08e-2)" 69.8 59.4 92.9 92.7 95.6 117.5 95.7 100.4 135.9 70.1 106.1 50.5 32.1 72.7 60.1 45.1 55.4 57.1 45.3 93.6 101.2 75.8 54.1 128.5 93.9 97.0 96.7 68.6 42.6 79.2 39.0 74.8 99.6 73.4 58.8 89.4 56.8 63.2 21.3 40.3 39.2 95.3 101.6 177.0 45.1 37.6 99.1 78.0 60.0 37.1 75.1 79.1 34.7 113.5 115.6 62.5 93.7 81.0 106.5 92.1 209.8 68.4 127.9 153.0 183.3 350.1 270.5 140.1 118.1 65.2 112.2 209.5 154.9 112.7 163.6 186.4 151.4 100.3 127.2 155.5 137.5 233.7 158.9 103.1 107.5 108.7 126.4 79.7 190.9 108.8 167.7 247.0 80.6 168.1 109.8 88.3 258.3 163.9 93.8 116.0 263.7 226.1 89.2 152.0 114.1 96.9 247.9 1082.7 298.6 111.7 199.3 1449.6 85.2 100.7 147.1 70.7 174.9 161.2 383.8 133.9 109.4 408.7 155.5 85.7 1254.3 624.2 122.2 1006.3 137.9 118.8 171.5 131.3 1091.1 118.6 227.0 168.3 683.9 100.3 815.7 101.8 204.1 1586.9 92.9 95.6 100.4 135.9 93.6 101.2 97.0 96.7 99.6 101.6 99.1 113.5 45.2 28.9 47.7 19.9 33.3 39.6 77.1 30.8 34.7 46.6 55.3 37.5 15.7 41.5 40.0 38.6 16.7 51.7 28.9 4.7 5.9 59.0 64.8 13.8 46.4 49.6 19.9 40.1 28.4 42.1 66.5 56.6 14.8 18.2 84.9 34.6 47.5 9.3 251.9 25.2 39.2 8.1 20.3 315.8 328.8 87.6 31.4 271.3 67.6 31.9 227.2 120.3 28.8 27.6 22.7 22.2 6.0 39.5 34.2 42.4 3.2 18.5 32.3 37.0 19.7 30.5 49.3 17.5 33.0 19.1 27.3 41.2 43.5 39.4 11.4 35.6 PPT2 ENSG00000221988 "Palmitoyl-protein thioesterase 2" Q9UMR5 6 32153441-32163678 "Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 33.6;Smooth muscle cells: 27.8;Syncytiotrophoblasts: 23.3" "Cancer enhanced" "Detected in all" "melanoma: 21.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 21.3;HEK 293: 27.9;SK-MEL-30: 29.4" HPA000414 Supported Vesicles "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA000414: " "unprognostic (1.90e-2)" "unprognostic (1.09e-1)" "unprognostic (2.95e-1)" "prognostic unfavorable (5.03e-5)" "unprognostic (1.62e-1)" "unprognostic (6.75e-3)" "unprognostic (2.92e-3)" "unprognostic (6.41e-3)" "unprognostic (7.12e-2)" "unprognostic (2.56e-3)" "unprognostic (5.28e-3)" "unprognostic (1.12e-2)" "unprognostic (2.75e-3)" "unprognostic (5.09e-2)" "unprognostic (2.94e-1)" "unprognostic (4.89e-2)" "unprognostic (1.24e-3)" 19.0 18.0 1.1 2.1 1.1 0.1 18.7 1.1 4.8 26.5 1.0 23.7 1.6 22.0 2.6 28.2 21.7 0.0 24.5 1.1 1.1 22.1 13.9 14.3 1.7 1.1 1.2 46.2 14.3 0.0 13.7 3.9 1.1 17.2 1.5 6.2 14.9 0.0 19.0 29.4 14.9 1.3 1.1 13.3 21.0 8.3 1.1 1.9 14.6 0.2 1.0 18.1 24.2 1.3 0.0 0.0 0.0 0.4 21.3 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 16.2 1.6 0.7 5.3 2.6 5.0 0.0 0.0 27.9 4.0 0.0 0.0 0.0 3.5 1.8 4.0 1.6 0.0 7.3 3.8 0.0 14.9 0.0 1.8 1.7 13.0 4.6 0.0 0.0 0.9 0.0 6.3 5.8 0.0 14.3 0.0 1.6 5.4 8.7 5.2 29.4 15.2 0.0 3.7 0.8 0.0 11.4 0.0 0.0 0.8 12.6 3.0 5.8 2.2 3.5 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.1 1.0 0.0 0.1 0.0 0.7 0.0 0.1 1.1 1.1 1.1 4.8 1.1 1.1 1.1 1.2 1.1 1.1 1.1 1.3 9.4 0.0 0.5 0.0 0.7 3.3 2.9 2.6 5.7 12.4 4.2 2.9 6.8 2.8 2.8 3.7 16.7 14.5 4.4 2.4 1.9 1.8 0.3 4.5 4.3 7.6 4.9 17.4 0.0 3.0 9.2 6.3 1.5 5.0 0.0 33.6 6.4 4.4 3.0 3.3 0.0 2.6 2.0 1.3 1.3 1.1 4.1 1.1 7.2 0.0 0.2 9.5 3.1 0.0 0.0 1.8 3.8 3.0 1.7 1.4 1.4 3.1 0.6 6.1 0.0 3.6 27.8 4.0 6.7 4.4 2.3 23.3 1.4 5.0 3.0 1.5 PRAF2 "JM4, Yip6a" ENSG00000243279 "PRA1 domain family member 2" O60831 X 49071161-49074002 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 163.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002859, HPA005504, CAB011655" Enhanced Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "CAB011655: , HPA002859: AB_1079672, HPA005504: AB_2667340" "unprognostic (1.50e-1)" "prognostic favorable (7.42e-4)" "unprognostic (1.17e-2)" "unprognostic (1.32e-2)" "unprognostic (4.29e-1)" "unprognostic (3.67e-1)" "prognostic unfavorable (1.66e-6)" "prognostic favorable (2.81e-4)" "unprognostic (6.10e-2)" "unprognostic (3.77e-1)" "prognostic favorable (4.88e-6)" "unprognostic (8.39e-3)" "prognostic unfavorable (5.83e-6)" "unprognostic (4.96e-2)" "unprognostic (1.69e-1)" "unprognostic (1.15e-1)" "unprognostic (1.50e-1)" 26.5 38.7 66.9 15.6 67.3 8.2 23.2 67.2 82.5 43.2 63.8 32.3 6.1 51.5 163.4 11.7 36.0 14.8 32.0 66.7 72.1 26.3 11.5 29.7 12.8 69.4 73.8 37.7 10.5 29.2 74.5 11.4 73.9 26.4 11.1 21.6 13.9 35.8 12.1 14.7 17.8 43.6 66.1 21.7 21.9 28.2 71.1 21.5 27.7 9.0 14.9 33.1 26.0 69.8 17.0 35.0 40.0 51.5 140.4 84.7 5.0 59.1 61.9 39.7 43.2 2.0 5.3 1.7 14.0 129.3 32.6 15.5 1.6 32.3 43.6 31.3 45.4 13.4 43.0 1.8 143.2 8.8 25.0 108.3 27.0 75.0 54.0 80.9 61.6 41.3 2.1 4.6 69.5 31.4 56.6 10.6 22.5 8.3 2.3 30.8 21.9 3.8 60.0 5.0 26.6 66.3 49.5 25.5 35.2 35.1 25.0 6.2 37.8 30.1 39.6 65.6 17.5 71.7 19.8 13.4 72.7 15.3 48.1 47.0 13.0 18.5 38.6 15.0 43.2 32.0 41.6 33.9 14.9 30.2 36.7 40.1 34.1 39.0 11.2 5.9 68.4 26.0 66.9 67.3 67.2 82.5 66.7 72.1 69.4 73.8 73.9 66.1 71.1 69.8 21.5 12.8 10.0 7.5 8.7 7.6 14.9 34.8 11.4 23.1 8.0 10.7 5.8 11.5 16.3 11.0 12.5 3.3 13.2 2.2 11.7 16.7 3.4 6.8 31.6 30.9 10.2 5.2 5.8 5.7 13.4 29.9 4.1 9.2 15.9 13.4 33.5 3.6 6.1 16.8 7.0 4.7 40.7 5.7 11.3 6.0 38.2 6.6 14.2 5.6 5.6 29.2 16.5 3.5 9.9 4.1 0.8 41.3 10.5 10.1 1.5 18.5 17.7 8.6 19.7 13.2 33.4 14.7 4.5 5.0 7.4 9.7 17.5 36.3 1.5 9.3 PRCP "HUMPCP, PCP" ENSG00000137509 Prolylcarboxypeptidase P42785 11 82822936-82970584 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatic stellate cells: 348.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 463.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017065, HPA071115" Approved Supported Vesicles "Intracellular and membrane" NA NA 42000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA017065: AB_1855676, HPA071115: " "unprognostic (3.24e-1)" "unprognostic (2.25e-1)" "unprognostic (1.76e-1)" "unprognostic (1.51e-1)" "unprognostic (2.54e-1)" "unprognostic (1.33e-2)" "unprognostic (9.22e-2)" "unprognostic (1.42e-1)" "unprognostic (7.97e-2)" "unprognostic (2.61e-1)" "unprognostic (2.70e-1)" "unprognostic (1.88e-2)" "prognostic favorable (2.65e-6)" "unprognostic (7.16e-2)" "unprognostic (1.73e-2)" "unprognostic (3.49e-1)" "unprognostic (4.07e-1)" 74.8 87.3 81.1 57.8 82.1 37.7 70.0 84.3 109.1 91.9 95.0 49.3 28.6 62.9 81.4 62.1 57.0 64.3 70.0 76.6 85.6 144.7 151.9 58.1 92.1 84.4 82.1 53.5 37.9 78.4 34.5 152.8 80.9 52.5 46.6 21.9 85.6 55.5 15.9 54.1 31.8 80.8 89.0 54.0 32.0 41.8 86.0 33.7 63.7 28.5 85.0 100.2 57.5 86.7 34.9 41.8 49.6 121.0 463.5 146.7 67.1 67.5 131.9 70.9 97.0 103.5 70.7 55.9 100.7 117.9 72.6 53.2 53.7 45.2 72.0 43.9 38.3 37.7 56.5 76.7 86.2 31.0 124.7 122.0 39.3 72.7 68.6 166.5 224.0 26.3 39.1 69.8 72.7 19.5 4.9 171.7 33.9 90.3 31.1 27.1 97.0 65.1 118.0 71.2 24.0 51.9 101.9 60.2 41.5 80.6 66.6 49.6 65.0 78.8 77.4 71.1 33.5 64.2 113.6 46.3 32.9 41.7 44.5 53.5 76.9 50.9 13.7 79.0 16.1 31.7 14.0 15.9 140.2 34.2 12.0 17.4 89.0 34.7 64.8 27.9 14.8 49.6 81.1 82.1 84.3 109.1 76.6 85.6 84.4 82.1 80.9 89.0 86.0 86.7 86.9 19.2 12.9 58.8 45.5 31.4 41.5 53.4 25.0 11.7 26.2 25.1 26.6 37.1 25.2 62.5 2.1 65.1 29.0 9.8 29.4 32.9 44.9 17.4 37.7 180.4 19.7 13.7 42.2 12.0 120.1 73.6 23.9 29.9 12.7 18.2 348.7 65.4 80.7 16.8 38.5 19.1 14.2 152.9 118.9 47.6 44.1 88.0 71.2 33.7 79.5 53.5 28.8 34.7 10.5 8.2 10.2 46.3 62.2 23.3 3.9 83.8 9.1 5.3 65.7 25.5 25.6 60.8 6.3 54.3 34.9 52.9 22.3 27.7 20.9 39.2 PRDM10 "KIAA1231, MGC131802, PFM7" ENSG00000170325 "PR/SET domain 10" Q9NQV6 11 129899706-130002835 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 22.5;Excitatory neurons: 21.3;Inhibitory neurons: 21.2;Oligodendrocytes: 21.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 44.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026997, HPA061749" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 37: B-cells - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Nucleoli fibrillar center, Vesicles" "HPA026997: AB_1855681, HPA061749: " "unprognostic (4.40e-2)" "unprognostic (2.17e-1)" "unprognostic (5.32e-3)" "unprognostic (2.03e-1)" "unprognostic (1.50e-1)" "unprognostic (1.52e-3)" "unprognostic (2.19e-2)" "unprognostic (2.48e-1)" "unprognostic (1.87e-3)" "unprognostic (3.33e-2)" "unprognostic (4.45e-2)" "unprognostic (3.57e-2)" "unprognostic (1.87e-1)" "unprognostic (5.69e-2)" "unprognostic (4.88e-1)" "unprognostic (6.23e-2)" "unprognostic (1.51e-1)" 2.8 2.4 2.5 3.1 2.5 7.9 4.2 7.4 3.3 3.2 2.8 3.4 3.4 3.0 3.3 4.0 2.6 2.8 2.0 2.9 3.4 2.2 3.5 3.0 3.9 1.8 1.8 3.4 3.1 3.4 4.6 2.6 1.9 3.4 3.9 4.7 3.1 2.5 6.7 6.2 3.7 2.5 0.9 3.1 4.0 2.4 3.3 6.7 3.0 3.8 4.0 2.6 3.4 4.0 4.7 6.1 7.7 5.1 3.4 4.1 5.1 3.9 5.0 3.2 4.1 6.2 4.8 17.8 4.5 4.6 4.4 6.1 6.4 3.2 5.2 6.6 5.5 12.3 7.5 5.0 2.2 10.9 44.8 2.9 7.1 4.8 3.1 4.9 5.7 5.0 7.0 6.6 4.7 5.2 6.7 5.7 5.9 6.3 4.4 6.5 4.8 2.9 4.7 8.0 8.3 4.3 5.7 6.4 1.7 4.3 4.5 4.8 5.7 7.2 3.4 3.8 5.1 1.7 3.0 25.1 3.2 6.1 5.9 2.4 2.2 6.0 2.6 2.5 2.6 6.8 2.1 2.2 2.1 3.6 3.1 1.4 6.3 4.4 2.7 2.1 2.9 1.4 2.5 2.5 7.4 3.3 2.9 3.4 1.8 1.8 1.9 0.9 3.3 4.0 2.7 3.2 2.7 22.5 3.2 6.1 2.6 1.8 6.8 3.7 3.5 2.2 2.7 1.5 2.0 0.0 0.0 1.5 2.5 6.3 0.0 1.2 3.0 2.9 2.7 1.8 1.8 8.6 21.3 1.1 1.2 2.7 4.6 3.2 1.3 2.7 1.1 2.3 1.6 1.7 21.2 3.1 2.0 3.1 2.9 4.1 2.5 2.8 0.0 13.1 2.1 1.0 1.0 13.6 21.6 0.9 3.2 1.9 2.4 4.6 3.1 1.0 2.3 2.7 0.0 3.9 3.4 0.8 0.8 7.2 5.1 0.5 3.5 1.7 2.7 5.8 PREX1 "KIAA1415, P-REX1" ENSG00000124126 "Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1" Q8TCU6 20 48624252-48827999 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 52.5;brain: 78.1" "Cell type enhanced" "Detected in many" "Astrocytes: 87.1;dendritic cells: 84.0;Kupffer cells: 104.7;Macrophages: 76.5;Microglial cells: 95.5;NK-cells: 90.6;Oligodendrocytes: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 157.9;SK-BR-3: 162.2;T-47d: 145.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001927 Supported Supported Vesicles,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 41: Macrophages - Immune response" "Vesicles, Cytosol" "HPA001927: AB_1079674" "unprognostic (8.07e-2)" "unprognostic (3.16e-2)" "unprognostic (2.15e-2)" "unprognostic (2.55e-1)" "unprognostic (7.47e-2)" "prognostic favorable (8.56e-4)" "unprognostic (2.16e-1)" "unprognostic (1.85e-1)" "unprognostic (1.31e-1)" "unprognostic (5.21e-2)" "unprognostic (1.13e-2)" "unprognostic (2.70e-2)" "unprognostic (5.86e-3)" "unprognostic (6.84e-2)" "unprognostic (2.31e-1)" "unprognostic (1.50e-1)" "unprognostic (1.01e-2)" 14.8 10.6 32.8 37.4 56.4 52.5 15.0 43.2 47.2 12.3 1.2 7.0 6.3 4.0 1.4 6.4 4.7 13.0 6.7 32.1 42.0 4.8 5.2 26.8 36.6 52.1 52.0 2.5 5.3 6.9 7.6 11.7 53.8 4.8 6.0 3.9 5.3 3.4 6.6 3.5 12.7 7.7 43.5 42.9 8.8 6.0 45.3 9.8 9.4 8.6 21.8 12.3 3.2 78.1 2.3 6.1 78.4 0.0 1.3 5.7 27.2 2.7 3.5 11.2 2.8 0.4 0.3 16.4 49.5 7.2 21.4 1.0 4.1 0.2 7.5 3.7 2.0 2.4 8.8 0.0 4.6 9.0 51.1 6.3 0.0 25.7 0.0 7.6 68.4 7.2 0.2 0.6 14.8 157.9 0.2 24.7 3.1 8.1 6.4 24.1 22.8 9.8 0.5 0.0 16.5 2.4 14.7 162.2 17.8 4.4 145.0 67.4 77.2 4.5 15.6 0.2 4.6 0.9 3.5 20.1 72.4 17.8 24.3 4.5 1.9 2.2 3.7 2.2 2.2 1.5 2.0 3.2 1.6 1.4 0.3 1.1 9.2 1.8 2.0 1.3 7.3 2.0 32.8 56.4 43.2 47.2 32.1 42.0 52.1 52.0 53.8 43.5 45.3 78.1 43.2 3.2 6.6 87.1 35.4 2.5 0.3 0.4 1.2 0.3 40.0 21.5 3.7 2.8 2.6 1.8 8.4 0.7 84.0 0.9 0.0 0.2 3.5 3.5 4.7 24.5 1.2 14.1 13.3 1.2 4.4 10.3 4.1 6.2 1.3 0.7 20.7 1.9 32.1 0.0 4.6 1.8 0.0 104.7 28.2 2.9 0.9 76.5 8.8 95.5 47.1 19.4 90.6 49.3 190.2 0.1 1.0 0.4 23.3 0.7 0.3 0.2 4.5 0.7 0.0 18.1 3.3 2.2 11.6 0.4 2.4 9.3 63.9 41.2 4.5 0.7 PRICKLE2 DKFZp686D143 ENSG00000163637 "Prickle planar cell polarity protein 2" Q7Z3G6 3 64092236-64445476 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Epilepsy, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 114.3;Excitatory neurons: 185.5;Inhibitory neurons: 232.4;Microglial cells: 112.4;Oligodendrocyte precursor cells: 103.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 24.1;ASC TERT1: 14.9;HSkMC: 22.1;U-87 MG: 15.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035493 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Vesicles "HPA035493: AB_10696504" "unprognostic (2.87e-1)" "unprognostic (4.31e-1)" "unprognostic (4.45e-2)" "unprognostic (1.25e-1)" "unprognostic (3.40e-1)" "unprognostic (3.53e-3)" "unprognostic (2.92e-2)" "unprognostic (1.56e-2)" "unprognostic (1.92e-1)" "unprognostic (3.83e-2)" "unprognostic (3.03e-2)" "unprognostic (6.35e-2)" "unprognostic (1.32e-3)" "unprognostic (1.10e-2)" "unprognostic (1.91e-1)" "unprognostic (9.04e-3)" "unprognostic (1.77e-1)" 20.8 3.0 14.1 3.9 14.9 0.3 8.0 3.4 15.8 16.4 9.1 18.4 2.3 17.3 6.8 7.7 11.7 8.8 5.6 28.5 10.0 3.8 3.1 10.6 0.8 4.4 8.9 8.4 3.8 5.4 5.6 5.6 6.2 7.3 4.6 10.1 4.9 13.8 1.9 4.3 5.9 16.6 6.3 1.4 8.1 1.7 11.7 1.0 6.9 3.9 1.0 12.4 8.8 9.3 0.0 4.7 1.3 0.1 24.1 14.9 0.0 3.5 4.5 2.8 4.2 8.3 0.1 0.0 0.5 3.4 7.6 0.1 0.0 3.2 2.8 3.3 0.1 0.0 0.5 0.1 6.7 0.0 0.0 22.1 4.0 8.2 3.5 8.4 1.7 0.0 0.0 1.8 3.9 4.6 0.0 0.1 3.0 0.0 0.1 0.0 0.2 0.1 4.5 11.7 1.2 0.2 0.0 0.9 0.1 7.7 1.6 0.1 0.1 11.9 5.4 2.9 6.9 3.7 0.0 0.7 15.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 14.1 14.9 3.4 15.8 28.5 10.0 4.4 8.9 6.2 6.3 11.7 9.3 12.4 0.0 10.9 114.3 1.5 6.2 4.1 7.3 7.4 25.6 4.3 8.4 6.2 1.5 7.3 3.7 64.6 1.4 0.3 1.6 0.0 2.7 15.1 24.7 47.5 9.5 0.0 0.0 185.5 0.4 0.4 20.3 0.0 8.7 0.0 5.2 33.5 1.7 4.1 16.8 232.4 0.6 4.1 1.2 1.8 3.5 9.9 0.6 5.4 112.4 0.0 7.5 1.0 103.5 26.4 0.7 0.3 23.0 0.2 0.9 0.0 6.2 7.6 4.4 13.1 14.6 14.3 2.0 1.0 6.2 3.0 4.9 0.6 6.6 1.1 2.7 PRKCE ENSG00000171132 "Protein kinase C epsilon" Q02156 2 45651345-46187990 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.5" "Cell type enhanced" "Detected in many" "Early spermatids: 206.5;Excitatory neurons: 394.4;Inhibitory neurons: 531.9;Late spermatids: 456.4;Oligodendrocyte precursor cells: 147.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 18.5;basal ganglia: 20.0;cerebral cortex: 34.5;hippocampal formation: 33.1;white matter: 17.1" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "REH: 27.0;TIME: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001948, HPA008236, HPA044496" Enhanced Supported Supported "Vesicles,Plasma membrane,Intermediate filaments,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Intermediate filaments, Cytosol" "Vesicles, Plasma membrane" "CAB001948: , HPA008236: , HPA044496: AB_2678959" "unprognostic (1.10e-1)" "unprognostic (1.78e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (9.61e-2)" "unprognostic (5.70e-2)" "unprognostic (1.51e-1)" "prognostic favorable (9.62e-4)" "unprognostic (3.05e-1)" "unprognostic (6.72e-2)" "unprognostic (7.49e-3)" "unprognostic (9.99e-2)" "prognostic favorable (2.63e-7)" "unprognostic (1.21e-1)" "unprognostic (7.11e-2)" "unprognostic (6.43e-3)" "unprognostic (2.23e-2)" 4.4 5.6 18.5 3.7 20.0 8.0 4.2 5.5 34.5 4.6 0.0 5.7 2.6 4.4 2.3 4.1 5.7 3.0 6.2 33.1 0.0 10.0 12.5 20.1 5.7 6.0 0.2 2.8 3.3 9.4 5.2 8.3 4.4 2.9 3.3 15.4 2.7 3.0 7.6 2.7 3.5 4.1 0.0 3.9 4.1 7.6 1.1 3.1 4.9 5.3 4.2 4.9 3.4 17.1 7.7 2.7 3.8 3.8 5.8 6.7 3.1 4.9 9.5 4.3 4.5 0.7 7.0 11.3 4.8 5.5 6.1 1.8 2.5 2.8 6.1 6.9 4.4 0.1 1.8 1.5 6.5 0.9 3.8 5.8 3.0 6.5 4.7 3.6 16.0 2.4 1.6 2.6 5.0 3.8 3.8 0.5 1.3 4.2 1.4 27.0 18.3 12.4 3.9 5.1 2.6 5.7 2.4 7.6 17.1 1.4 6.1 2.6 26.8 8.2 8.5 6.1 5.1 0.0 0.0 9.3 6.7 6.3 8.4 0.0 0.5 0.7 0.3 0.1 0.4 1.5 0.2 0.2 0.8 1.8 0.5 0.1 0.1 0.4 0.6 0.3 0.0 0.3 18.5 20.0 5.5 34.5 33.1 0.0 6.0 0.2 4.4 0.0 1.1 17.1 12.6 6.4 9.2 90.4 20.7 5.0 8.4 5.0 9.1 55.3 6.4 5.7 11.9 8.6 17.2 11.0 14.6 0.5 9.3 6.1 3.9 3.7 206.5 6.8 7.0 13.8 7.7 0.4 394.4 3.8 7.2 8.7 11.2 6.9 7.0 2.9 13.2 12.5 2.8 11.8 531.9 5.8 0.0 19.0 10.7 456.4 5.3 11.5 14.2 70.3 9.4 6.5 1.0 147.8 96.0 3.6 2.9 6.0 4.2 5.3 4.1 30.2 19.3 7.6 13.1 2.9 6.4 2.8 2.3 9.0 4.8 2.9 6.8 1.2 6.2 8.8 PRKG1 "PGK, PKG, PKG1, PRKG1B, PRKGR1B" ENSG00000185532 "Protein kinase cGMP-dependent 1" Q13976 10 50990888-52298423 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 36.1" "Cell type enhanced" "Detected in many" "Astrocytes: 778.3;Excitatory neurons: 244.9;Inhibitory neurons: 473.0;Microglial cells: 188.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 36 "basophil: 7.3" "Lineage enriched" "Detected in single" 49 "granulocytes: 7.3" "Cell line enhanced" "Detected in many" "AN3-CA: 14.3;BJ hTERT+: 19.2;fHDF/TERT166: 16.1;U-138 MG: 11.2;U-87 MG: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007699, CAB009629" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Cytosol" "CAB009629: AB_2170663, HPA007699: AB_1079677" "unprognostic (3.94e-2)" "unprognostic (2.60e-1)" "unprognostic (1.44e-2)" "unprognostic (5.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.86e-1)" "unprognostic (5.54e-1)" "unprognostic (2.23e-1)" "unprognostic (4.94e-1)" "unprognostic (2.05e-2)" "unprognostic (1.22e-2)" "unprognostic (3.40e-1)" "unprognostic (9.26e-2)" "unprognostic (5.50e-3)" "unprognostic (4.24e-2)" "unprognostic (1.11e-1)" "unprognostic (3.78e-4)" 7.0 8.3 6.4 2.7 7.2 0.6 3.1 1.4 6.9 10.3 12.4 5.5 2.4 10.3 3.5 5.2 5.2 7.0 14.1 6.6 10.7 3.8 1.7 6.8 1.2 5.1 4.6 4.2 1.7 9.6 1.3 10.1 3.2 6.4 5.3 3.6 4.0 8.1 25.8 1.0 3.4 14.6 5.3 2.5 3.3 1.8 12.2 1.5 7.0 36.1 0.9 5.4 4.2 2.7 0.1 0.2 1.7 14.3 6.5 6.0 0.1 5.4 19.2 2.1 2.6 0.1 0.9 0.3 0.0 16.1 2.0 0.1 0.0 0.1 1.7 0.0 5.0 1.0 0.3 0.0 5.5 0.0 0.1 8.1 0.1 4.8 0.1 0.6 0.0 0.0 0.0 0.1 5.3 0.1 0.0 0.0 4.1 0.0 2.5 0.0 3.9 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.1 2.0 0.1 0.0 0.0 11.2 1.9 5.9 3.7 1.5 0.8 0.0 10.0 0.0 2.5 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 6.4 7.2 1.4 6.9 6.6 10.7 5.1 4.6 3.2 5.3 12.2 2.7 10.5 16.0 10.8 778.3 0.3 0.9 1.7 0.0 7.4 5.9 2.8 9.4 31.4 0.0 0.0 3.7 0.0 1.0 0.3 2.9 0.0 2.4 56.0 0.4 14.7 7.1 0.0 3.4 244.9 3.6 1.2 24.2 0.5 0.5 4.5 0.1 5.0 0.0 0.4 0.0 473.0 4.2 0.0 0.0 2.2 53.0 32.6 5.3 3.6 188.3 0.0 23.6 0.0 24.6 8.0 4.8 14.1 39.5 0.1 0.5 3.2 0.2 0.9 1.3 39.5 3.9 69.9 0.9 0.9 1.6 0.6 2.2 0.2 7.9 3.6 1.0 PRNP "AltPrP, CD230, CJD, GSS, PRIP, PRP" ENSG00000171867 "Prion protein" P04156 20 4686350-4701590 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell cycle, Growth arrest" Prion "Amyloidosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 412.6;Basal squamous epithelial cells: 369.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "basophil: 875.9" "Lineage enriched" "Detected in all" 9 "granulocytes: 875.9" "Cell line enhanced" "Detected in many" "WM-115: 1039.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042754, HPA043398" Enhanced Approved "Nuclear membrane,Vesicles,Cytosol" NA Yes 5100000 "Cluster 38: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 41: Macrophages - Immune response" "Nuclear membrane, Cytosol" Vesicles "HPA042754: AB_10964203, HPA043398: AB_2678461" "unprognostic (1.50e-1)" "unprognostic (1.72e-1)" "prognostic unfavorable (2.96e-4)" "prognostic unfavorable (4.64e-4)" "prognostic unfavorable (2.52e-4)" "unprognostic (1.94e-2)" "prognostic unfavorable (7.41e-5)" "unprognostic (7.60e-3)" "unprognostic (2.50e-1)" "unprognostic (7.12e-2)" "unprognostic (3.44e-1)" "unprognostic (1.04e-1)" "unprognostic (6.75e-2)" "unprognostic (7.28e-3)" "unprognostic (3.37e-1)" "unprognostic (2.04e-1)" "unprognostic (1.69e-2)" 87.0 92.4 283.8 52.4 308.4 83.7 106.7 255.1 385.9 135.4 415.8 184.2 37.1 125.5 59.1 79.2 79.9 110.1 197.5 315.6 244.8 132.8 79.7 79.2 59.8 262.8 260.8 163.7 41.5 62.8 83.8 66.9 270.1 146.1 70.5 178.6 60.3 148.2 64.0 95.4 47.4 140.8 265.0 75.2 61.6 68.1 302.5 47.9 89.1 74.0 60.0 124.9 83.4 292.8 226.4 141.6 41.7 64.2 329.6 199.9 36.6 363.4 527.6 175.5 177.7 50.0 171.5 40.9 79.2 727.9 391.8 508.8 45.9 498.3 326.2 31.8 39.0 0.2 19.6 193.8 402.0 72.8 16.5 177.5 711.9 701.8 583.9 257.0 152.8 28.6 22.8 142.9 205.1 45.7 28.8 46.2 33.1 99.8 266.4 33.9 110.0 38.3 88.7 40.3 49.2 7.0 98.9 144.3 554.1 56.4 30.2 38.8 224.5 282.9 127.1 158.6 296.1 63.1 129.5 132.9 226.8 51.9 1039.0 875.9 74.1 5.4 67.3 60.9 100.7 25.1 56.9 55.8 62.9 25.6 33.5 40.1 4.6 23.6 50.4 24.6 72.8 72.7 283.8 308.4 255.1 385.9 315.6 244.8 262.8 260.8 270.1 265.0 302.5 292.8 44.9 80.1 45.4 120.2 85.3 412.6 211.8 132.5 369.3 265.4 60.8 103.0 257.7 32.9 68.2 33.1 116.7 7.7 71.8 2.6 11.7 58.1 6.0 14.1 73.2 66.7 29.9 31.8 125.5 14.7 6.3 177.4 14.8 18.2 173.0 25.5 41.0 36.2 63.6 45.4 170.8 5.4 40.7 219.1 200.4 13.6 143.2 126.3 168.9 59.0 54.5 142.4 42.2 95.0 158.8 18.7 4.5 170.0 47.0 120.3 2.2 84.0 38.1 99.0 13.1 73.0 82.3 36.6 4.5 81.6 284.4 14.4 107.2 10.3 8.8 122.6 PRODH "HSPOX2, PIG6, PRODH1, PRODH2, TP53I6" ENSG00000100033 "Proline dehydrogenase 1" O43272 22 18912777-18936553 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Proline metabolism" Oxidoreductase "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 49.2;skin 1: 39.8" "Cell type enriched" "Detected in some" 7 "Astrocytes: 183.1" "Cancer enhanced" "Detected in many" "testis cancer: 11.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "OE19: 91.3;RPTEC TERT1: 35.9" HPA020361 Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 59: Non-specific - Translation" "Cluster 21: OE19 - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" Mitochondria "Nucleoplasm, Vesicles" "HPA020361: AB_10963116" "unprognostic (2.46e-2)" "prognostic favorable (1.54e-4)" "unprognostic (1.40e-1)" "unprognostic (3.70e-2)" "unprognostic (3.80e-2)" "unprognostic (1.20e-1)" "unprognostic (1.78e-2)" "unprognostic (1.07e-2)" "unprognostic (2.49e-2)" "unprognostic (6.56e-2)" "unprognostic (3.12e-2)" "unprognostic (1.61e-2)" "unprognostic (7.44e-2)" "unprognostic (1.07e-1)" "unprognostic (1.21e-1)" "unprognostic (5.34e-2)" "unprognostic (3.94e-2)" 7.9 0.7 5.8 0.4 6.4 0.0 8.5 3.1 9.0 5.0 34.0 3.1 5.6 1.5 0.1 11.6 5.8 0.1 18.6 6.5 2.8 16.7 15.6 20.6 0.2 7.3 4.7 0.5 1.4 0.0 5.4 0.2 2.5 3.2 0.3 0.6 4.2 0.2 49.2 39.8 32.5 0.0 3.3 0.5 3.5 1.7 7.6 0.3 7.4 6.2 0.8 4.2 8.5 3.4 0.0 0.8 0.0 0.3 0.9 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.1 0.0 0.3 0.0 0.0 2.9 3.9 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 2.9 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.6 4.5 91.3 0.0 0.0 0.0 0.4 35.9 0.9 0.1 0.2 0.8 1.4 0.3 5.2 1.4 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.8 6.4 3.1 9.0 6.5 2.8 7.3 4.7 2.5 3.3 7.6 3.4 0.1 16.0 25.6 183.1 0.0 5.1 0.3 13.1 0.0 0.0 0.2 0.1 1.8 0.0 11.5 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.6 1.2 0.2 0.4 3.5 0.0 0.5 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.0 2.0 0.0 1.5 0.1 0.0 0.1 21.4 17.8 0.0 0.6 0.0 14.1 2.1 0.0 2.3 0.0 0.0 0.0 8.0 0.1 21.0 0.1 0.0 1.1 0.6 0.2 0.4 1.0 15.2 0.0 0.3 0.0 1.6 0.2 PRPS1 "CMTX5, DFN2, DFNX1" ENSG00000147224 "Phosphoribosyl pyrophosphate synthetase 1" P60891 X 107628428-107651993 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Gout, Mental retardation, Neurodegeneration, Neuropathy, Non-syndromic deafness, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043760, HPA051269" Uncertain Approved Vesicles NA NA 320000 "Cluster 13: T-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Vesicles "HPA043760: AB_2678656, HPA051269: " "unprognostic (4.47e-2)" "unprognostic (6.18e-2)" "unprognostic (2.57e-2)" "unprognostic (4.19e-3)" "unprognostic (2.30e-3)" "unprognostic (2.56e-3)" "unprognostic (3.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.46e-1)" "unprognostic (9.73e-2)" "unprognostic (1.91e-2)" "unprognostic (4.11e-2)" "unprognostic (2.85e-2)" "unprognostic (4.57e-2)" "unprognostic (1.29e-1)" "unprognostic (1.25e-2)" "unprognostic (5.25e-2)" 22.9 28.0 33.7 30.2 35.0 58.0 21.0 32.4 36.4 20.0 59.3 19.0 11.0 23.7 14.8 13.7 25.9 13.9 22.2 33.7 39.6 27.6 51.5 21.5 42.7 35.4 39.1 30.2 21.7 27.2 23.2 14.6 37.6 21.3 17.9 30.2 16.3 17.4 49.1 12.3 16.7 29.5 34.2 26.2 15.5 13.4 35.2 52.0 44.1 37.9 45.7 23.6 15.2 34.4 93.5 128.9 56.4 69.9 32.7 26.5 18.6 253.2 55.8 146.0 122.6 55.5 36.6 156.9 111.7 94.9 104.1 36.6 176.0 53.8 148.3 79.9 150.9 84.2 140.0 100.3 28.8 153.1 55.6 28.2 30.6 90.2 56.2 96.7 52.3 108.2 137.4 183.5 69.0 51.0 101.2 113.6 213.5 77.2 141.4 117.6 96.3 125.4 60.7 54.2 96.2 52.5 131.5 77.6 57.3 106.4 36.0 61.7 31.2 93.2 45.0 108.3 109.1 61.8 115.1 172.7 50.1 163.6 61.6 8.8 8.9 22.6 26.0 14.3 30.8 29.3 31.7 32.2 11.4 31.0 36.1 30.7 4.7 28.5 15.7 16.3 35.5 21.1 33.7 35.0 32.4 36.4 33.7 39.6 35.4 39.1 37.6 34.2 35.2 34.4 21.0 6.4 10.0 4.6 44.2 31.1 18.4 13.2 12.0 28.4 8.3 9.4 12.1 15.7 12.6 16.5 4.2 8.8 29.3 3.0 25.4 18.3 1.2 11.5 13.3 18.1 16.2 52.2 4.8 20.2 11.5 22.2 10.2 5.7 26.6 13.2 14.6 57.5 35.3 15.2 10.0 6.5 6.1 18.6 34.8 3.9 14.0 16.8 26.6 6.5 24.9 20.0 27.8 3.5 4.8 19.1 3.7 17.0 35.7 16.2 1.5 29.4 27.1 14.1 0.0 18.1 30.7 3.6 10.9 10.8 22.3 1.8 45.0 19.7 8.0 9.7 PRPS1L1 "PRPS3, PRPSL" ENSG00000229937 "Phosphoribosyl pyrophosphate synthetase 1 like 1" P21108 7 18026770-18027846 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 315 "testis: 31.5" "Group enriched" "Detected in some" 7 "Early spermatids: 71.0;Spermatocytes: 129.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051269 Uncertain Vesicles NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA051269: " "unprognostic (2.39e-2)" "unprognostic (3.18e-2)" "unprognostic (1.11e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 71.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 6.6 0.0 1.1 129.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRPS2 ENSG00000101911 "Phosphoribosyl pyrophosphate synthetase 2" P11908 X 12791355-12824222 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 147.8;parathyroid gland: 182.0" "Group enriched" "Detected in many" 7 "Leydig cells: 1431.5;Peritubular cells: 1995.0;Sertoli cells: 624.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051269, HPA067599, CAB070417" Enhanced Approved "Nuclear speckles,Vesicles" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Transcription" Vesicles "Nuclear speckles" "CAB070417: AB_11152035, HPA051269: , HPA067599: AB_2685869" "unprognostic (7.50e-2)" "prognostic favorable (1.90e-4)" "unprognostic (2.09e-3)" "unprognostic (1.03e-1)" "unprognostic (1.16e-2)" "unprognostic (1.10e-1)" "unprognostic (7.63e-2)" "unprognostic (4.75e-2)" "unprognostic (6.98e-2)" "unprognostic (2.64e-3)" "unprognostic (4.44e-3)" "unprognostic (1.81e-1)" "unprognostic (7.83e-2)" "unprognostic (2.20e-1)" "unprognostic (1.50e-1)" "unprognostic (1.35e-1)" "unprognostic (2.04e-1)" 11.0 46.0 6.3 24.5 7.3 24.2 19.7 1.9 12.0 54.5 2.5 30.3 14.0 32.8 26.5 16.1 29.7 28.1 5.4 6.9 2.9 28.0 26.1 13.1 36.8 3.0 6.5 147.8 62.8 182.0 3.4 6.1 2.2 21.9 31.3 1.3 27.9 84.0 2.1 21.9 15.8 24.3 4.4 15.6 32.5 131.1 8.8 44.6 18.1 4.2 31.5 22.5 21.2 6.4 114.2 63.7 22.1 40.3 26.7 31.8 14.6 54.4 26.8 53.1 51.1 46.3 78.7 34.9 24.2 23.5 45.3 79.9 43.1 53.7 61.5 89.7 108.0 41.7 49.6 43.3 24.7 77.3 38.9 30.5 35.0 39.1 51.7 26.9 22.1 86.8 30.4 39.8 45.2 68.5 117.6 34.7 49.9 81.0 107.3 61.5 102.7 79.5 33.0 81.7 46.1 33.6 64.9 2.1 38.9 30.2 58.8 32.4 24.9 41.8 32.0 162.5 55.5 103.6 41.3 76.8 44.4 39.4 67.4 25.9 20.1 9.4 17.2 19.4 19.9 27.8 25.0 16.4 28.2 30.6 31.7 23.0 8.0 24.3 12.3 19.9 22.6 28.2 6.3 7.3 1.9 12.0 6.9 2.9 3.0 6.5 2.2 4.4 8.8 6.4 12.2 3.2 8.7 0.7 25.4 64.0 48.5 16.2 41.5 0.6 53.1 15.9 2.0 11.5 12.4 55.2 0.0 1.1 18.5 21.1 72.4 19.3 12.1 24.7 62.5 14.5 21.8 28.4 14.8 39.2 7.3 25.8 31.1 26.4 27.9 16.2 10.4 13.7 24.4 0.0 6.3 27.9 8.2 21.4 44.3 65.8 1431.5 20.7 40.9 3.7 18.2 1.2 18.6 3.5 5.1 24.6 17.4 1995.0 30.7 52.2 6.0 10.4 20.3 0.2 624.5 9.4 19.2 10.3 8.1 29.2 43.8 0.4 27.2 179.2 50.2 36.9 PRR15 ENSG00000176532 "Proline rich 15" Q8IV56 7 29563835-29567293 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 62.6;intestine: 81.4;stomach 1: 49.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 263.0;Granulosa cells: 194.2;Proximal enterocytes: 122.4;Respiratory ciliated cells: 63.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 38.7;HaCaT: 45.1;OE19: 97.7;RT4: 34.5;SK-BR-3: 74.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA040996, HPA048121" Enhanced Uncertain "Vesicles,Cell Junctions" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Cell Junctions" "HPA040996: AB_2677241, HPA048121: AB_2680271" "unprognostic (5.46e-2)" "unprognostic (1.27e-1)" "unprognostic (8.97e-2)" "prognostic favorable (6.37e-4)" "unprognostic (7.49e-2)" "unprognostic (1.96e-2)" "unprognostic (2.00e-1)" "prognostic unfavorable (7.23e-4)" "unprognostic (2.95e-1)" "unprognostic (2.45e-2)" "unprognostic (3.69e-3)" "unprognostic (1.25e-1)" "prognostic favorable (1.83e-6)" "unprognostic (1.30e-2)" "unprognostic (5.71e-2)" "unprognostic (2.33e-3)" "unprognostic (1.58e-2)" 6.5 0.7 0.6 4.8 0.4 1.1 9.2 0.1 0.7 62.6 0.0 81.4 72.3 18.1 21.6 1.0 9.0 7.8 1.3 0.4 1.0 16.9 0.3 2.3 0.4 0.6 0.4 5.9 3.0 1.4 3.0 4.8 0.5 2.5 52.6 0.0 7.5 3.1 0.2 0.3 72.4 2.3 0.6 0.2 49.3 0.9 1.3 0.1 1.1 0.0 0.7 16.6 0.5 0.6 16.8 23.3 0.0 0.0 8.7 10.7 29.3 0.7 1.1 0.4 0.2 20.5 38.7 0.0 4.1 5.5 0.6 45.1 4.9 0.0 0.0 0.0 3.3 1.3 4.5 22.7 2.8 0.0 0.1 0.1 7.3 0.0 1.7 0.0 0.1 1.5 0.0 0.0 0.0 3.9 0.6 3.2 3.5 97.7 18.5 0.1 0.0 21.4 26.5 34.5 0.5 0.3 2.3 74.9 0.0 12.8 5.4 0.0 19.9 0.5 0.0 0.1 0.9 1.8 3.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.4 0.1 0.7 0.4 1.0 0.6 0.4 0.5 0.6 1.3 0.6 1.8 0.0 0.5 0.0 0.4 0.1 1.2 11.0 0.0 0.0 10.0 7.1 0.5 12.8 16.4 38.6 0.0 14.2 0.2 263.0 29.4 6.9 0.8 31.3 2.3 1.2 8.4 0.0 0.1 21.8 9.9 1.3 16.8 34.7 0.0 194.2 0.4 0.2 2.7 0.0 0.0 45.3 26.4 0.0 0.3 0.1 1.5 2.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 14.4 58.5 2.2 0.1 3.0 122.4 14.4 63.1 0.0 0.0 0.0 7.8 0.0 0.4 1.2 0.0 6.3 0.6 0.4 56.9 23.3 PRR22 MGC24975 ENSG00000212123 "Proline rich 22" Q8IZ63 19 5782960-5784746 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 50.1" "Group enriched" "Detected in many" 6 "Early spermatids: 194.8;Late spermatids: 87.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 17.3" "Not detected" "Not detected" HPA044157 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "Vesicles, Cytosol" "HPA044157: AB_10960694" "unprognostic (8.09e-2)" "unprognostic (1.53e-3)" "unprognostic (5.19e-3)" "unprognostic (7.53e-2)" "unprognostic (1.25e-1)" "unprognostic (1.80e-1)" "unprognostic (3.20e-2)" "unprognostic (2.89e-2)" "unprognostic (1.20e-1)" "unprognostic (3.77e-2)" "unprognostic (3.42e-3)" "unprognostic (9.37e-3)" "unprognostic (4.18e-2)" "unprognostic (9.93e-4)" "unprognostic (1.07e-1)" "unprognostic (5.07e-1)" "unprognostic (2.79e-3)" 1.9 2.7 1.6 1.5 1.9 1.9 3.0 1.6 2.8 3.4 0.9 3.9 2.5 2.2 0.6 4.9 5.5 0.6 2.5 1.6 1.4 7.1 11.8 2.3 1.4 2.0 1.5 3.3 6.3 0.5 3.8 0.9 1.6 7.1 0.3 0.8 5.0 0.4 1.4 5.9 5.9 0.3 1.3 6.4 4.0 50.1 2.0 0.9 6.1 0.1 0.5 2.4 3.0 2.2 2.1 3.5 1.5 7.3 0.0 0.2 7.2 1.5 0.6 1.1 1.7 3.6 2.0 3.3 4.0 0.3 0.8 2.6 1.1 1.5 0.2 5.1 11.3 1.5 1.8 1.3 0.6 3.4 17.3 0.8 1.2 1.6 0.5 0.1 0.3 3.9 8.4 0.0 0.9 7.9 4.1 4.3 8.9 0.3 3.6 4.0 1.4 5.2 0.3 2.4 1.9 3.6 0.3 2.6 4.4 0.3 3.0 2.8 1.1 2.6 7.2 9.5 1.8 10.0 8.6 6.4 0.2 7.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.9 1.6 2.8 1.6 1.4 2.0 1.5 1.6 1.3 2.0 2.2 0.7 3.2 0.5 1.6 0.8 0.3 0.5 1.3 0.0 5.9 1.8 2.2 0.3 1.5 2.5 3.7 0.0 2.2 1.8 2.3 0.0 1.0 194.8 1.5 1.1 0.9 2.4 0.0 1.6 0.7 1.0 0.9 1.5 2.0 0.0 2.9 1.1 2.6 1.1 5.0 2.1 2.5 0.0 1.3 0.2 87.6 2.1 0.6 0.0 2.8 0.0 2.4 1.0 1.5 2.0 0.8 1.8 0.4 0.1 1.2 4.3 1.5 1.2 6.3 6.6 0.8 0.5 20.4 7.4 1.2 1.1 1.8 0.5 1.6 3.3 0.5 PRR9 ENSG00000203783 "Proline rich 9" Q5T870 1 153217584-153219310 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "skin 1: 59.3" "Group enriched" "Detected in some" 5 "Early spermatids: 4.1;Late spermatids: 10.2;Syncytiotrophoblasts: 8.9" "Group enriched" "Detected in many" 6 "cervical cancer: 4.2;endometrial cancer: 4.1;head and neck cancer: 11.8;melanoma: 3.4;urothelial cancer: 6.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "SuSa: 17.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA027714 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 61: Skin - Cornification" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "Nucleoplasm, Vesicles" "HPA027714: AB_10602194" "unprognostic (1.45e-1)" "unprognostic (1.46e-1)" "unprognostic (4.17e-1)" "unprognostic (3.48e-1)" "unprognostic (7.02e-2)" "unprognostic (8.27e-2)" "unprognostic (1.89e-1)" "unprognostic (1.23e-2)" 1.0 0.0 0.1 0.0 0.0 0.4 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 59.3 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.6 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 17.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 4.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 PRRC1 FLJ32875 ENSG00000164244 "Proline rich coiled-coil 1" Q96M27 5 127517640-127555085 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039212 Supported Approved Vesicles NA NA 170000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA039212: AB_10794634" "prognostic unfavorable (9.35e-5)" "unprognostic (9.01e-2)" "unprognostic (5.26e-3)" "unprognostic (6.36e-2)" "unprognostic (2.95e-1)" "unprognostic (4.47e-2)" "unprognostic (4.21e-2)" "unprognostic (1.39e-1)" "unprognostic (6.08e-2)" "unprognostic (1.04e-1)" "unprognostic (1.74e-3)" "unprognostic (5.53e-2)" "unprognostic (3.20e-3)" "unprognostic (1.57e-1)" "unprognostic (2.83e-1)" "unprognostic (3.45e-3)" "unprognostic (2.19e-1)" 17.3 18.7 7.0 18.1 8.1 21.2 24.2 8.3 9.3 27.5 12.4 23.5 25.3 22.0 23.4 20.2 15.9 17.1 14.5 6.5 7.6 21.4 26.7 18.2 17.9 7.9 8.0 22.3 32.1 30.4 19.1 27.0 8.6 21.1 27.2 11.5 25.6 18.0 12.9 19.2 24.4 22.4 7.8 16.2 24.0 13.2 7.5 19.5 26.6 10.2 20.9 19.4 17.3 9.9 30.3 30.5 44.5 34.0 58.8 75.1 51.9 52.3 58.4 45.7 71.8 52.4 34.6 33.6 53.2 83.6 34.4 26.9 35.0 64.8 70.6 46.7 24.4 29.3 29.1 45.6 33.8 27.4 36.9 51.5 46.7 48.5 56.3 41.9 49.4 31.6 25.5 40.2 53.4 34.2 53.9 29.4 25.5 43.5 39.5 20.5 58.9 43.8 36.4 37.6 32.4 25.0 41.0 44.1 40.1 40.6 47.2 35.3 58.9 41.8 31.2 49.3 37.2 33.5 26.8 43.6 49.3 42.9 42.0 18.7 11.7 9.4 18.6 13.5 22.6 15.4 15.1 16.0 15.6 11.2 16.5 14.9 3.6 12.7 13.5 10.4 13.0 12.3 7.0 8.1 8.3 9.3 6.5 7.6 7.9 8.0 8.6 7.8 7.5 9.9 16.3 35.3 25.5 9.8 17.8 14.7 14.0 37.2 22.8 12.8 24.1 15.0 12.5 27.1 40.6 27.6 14.6 25.5 14.0 38.2 13.7 30.5 3.8 16.2 33.6 22.8 15.6 12.4 13.5 30.9 42.2 30.8 28.5 23.2 15.8 28.7 26.0 37.3 21.7 8.4 13.5 50.2 28.5 20.2 7.6 4.8 34.5 14.7 19.6 15.9 17.8 10.7 22.6 18.6 25.1 31.8 25.1 30.1 38.0 26.6 34.1 28.0 30.0 12.7 13.1 18.8 26.4 13.6 21.2 18.2 18.6 31.6 19.3 21.7 33.6 26.0 PRRG1 PRGP1 ENSG00000130962 "Proline rich and Gla domain 1" O14668 X 37349309-37457292 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.4" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 229.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 79.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078129 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" Nucleoplasm "HPA078129: AB_2686878" "unprognostic (8.82e-2)" "prognostic unfavorable (4.65e-4)" "unprognostic (8.34e-2)" "unprognostic (2.08e-3)" "unprognostic (1.92e-1)" "unprognostic (5.11e-3)" "unprognostic (2.24e-2)" "unprognostic (7.23e-3)" "unprognostic (1.01e-2)" "unprognostic (1.74e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (8.21e-2)" "prognostic favorable (2.05e-7)" "unprognostic (1.43e-2)" "unprognostic (1.81e-1)" "unprognostic (1.08e-2)" "unprognostic (1.48e-1)" 8.6 3.7 12.3 2.1 24.9 0.2 5.2 21.6 19.7 4.4 4.7 4.0 2.9 4.3 1.5 4.1 2.6 8.8 6.4 12.9 15.9 10.5 7.9 5.5 1.7 26.7 21.3 4.2 1.6 1.2 1.4 8.1 25.3 3.4 4.1 1.5 2.9 7.8 15.9 2.2 3.0 5.4 18.4 2.9 2.4 1.5 18.4 1.5 8.3 7.8 1.0 5.6 3.8 39.4 32.3 7.2 5.6 5.6 18.7 15.4 2.4 14.1 17.6 4.7 8.2 17.1 20.2 0.0 21.8 10.4 8.9 10.7 15.6 10.0 8.3 0.1 5.2 5.2 7.7 5.7 22.6 0.0 7.2 23.2 8.1 9.1 7.7 9.4 24.8 0.0 2.6 0.1 16.5 2.4 0.1 0.1 6.8 5.1 13.4 0.0 13.1 0.0 79.2 1.7 0.0 0.1 9.7 15.6 6.1 15.3 0.1 3.5 17.6 7.5 4.2 14.2 4.1 0.0 0.1 0.0 7.3 0.0 7.3 0.7 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.3 24.9 21.6 19.7 12.9 15.9 26.7 21.3 25.3 18.4 18.4 39.4 29.7 6.4 4.2 15.7 0.0 11.3 4.8 7.6 5.2 2.2 5.3 5.3 8.1 15.7 2.7 33.1 0.0 7.0 0.2 7.6 7.9 6.8 0.7 3.3 12.9 18.4 3.0 0.0 23.3 3.1 14.9 9.6 4.6 9.2 1.3 3.9 17.9 16.3 4.8 18.5 10.8 5.7 14.2 4.1 5.3 0.4 4.7 1.4 3.6 31.9 0.8 2.2 0.0 12.5 229.8 18.7 7.5 2.6 0.0 9.1 4.3 9.4 2.9 0.5 6.6 8.3 8.4 2.5 4.2 5.2 6.3 10.4 0.4 3.5 4.8 8.1 PRSS1 TRY1 ENSG00000204983 "Serine protease 1" P07477 7 142749468-142753076 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1923 "pancreas: 341429.7" "Cell type enriched" "Detected in some" 28 "Exocrine glandular cells: 57138.3" "Cancer enriched" "Detected in many" 224 "pancreatic cancer: 1920.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "OE19: 10.6;RPMI-8226: 4.5;U-2 OS: 2.8" "CAB025487, CAB025538, HPA062452, HPA063471" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" NA NA 100000000000 "Cluster 35: T-regs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 1: Pancreatic cells - Digestion" Vesicles "Endoplasmic reticulum" "CAB025487: , CAB025538: , HPA062452: AB_2684768, HPA063471: AB_2685017" "unprognostic (6.55e-5)" "unprognostic (5.28e-1)" "unprognostic (7.58e-2)" "prognostic unfavorable (6.41e-6)" "unprognostic (8.26e-2)" "prognostic favorable (7.05e-4)" "unprognostic (1.35e-1)" "unprognostic (3.93e-2)" "unprognostic (1.96e-1)" "prognostic favorable (4.91e-4)" "unprognostic (3.12e-1)" 45.2 9.9 0.0 4.7 0.0 0.0 25.7 0.0 0.0 19.9 0.0 11.2 54.5 8.9 0.8 15.2 5.6 0.0 51.0 0.0 0.0 9.6 29.7 6.4 6.5 0.0 0.0 177.5 341429.7 0.1 10.3 13.9 0.0 15.2 0.0 0.0 44.2 4.2 8.9 12.1 12.7 0.0 0.0 13.4 77.1 6.9 0.0 0.0 6.4 0.0 0.0 4.7 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 100.7 0.0 0.1 0.0 3.6 0.0 0.0 0.0 57138.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 119.4 0.6 0.0 0.0 0.0 1985.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.2 0.2 PRSS2 TRY2 ENSG00000275896 "Serine protease 2" P07478 7 142760398-142774564 "Enzymes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 452 "pancreas: 239420.0" "Cell type enriched" "Detected in some" 11 "Exocrine glandular cells: 108258.7" "Cancer enriched" "Detected in many" 72 "pancreatic cancer: 3463.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "basophil: 4.1;T-reg: 2.9" "Group enriched" "Detected in many" 8 "granulocytes: 4.1;T-cells: 2.9" "Cell line enhanced" "Detected in some" "OE19: 21.0;RPMI-8226: 67.5;U-2 OS: 15.2" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" NA NA 890000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 1: Pancreatic cells - Digestion" Vesicles "Endoplasmic reticulum" "HPA062452: AB_2684768, HPA063471: AB_2685017" "prognostic favorable (2.32e-4)" "unprognostic (3.80e-1)" "unprognostic (2.46e-1)" "unprognostic (3.30e-3)" "unprognostic (1.99e-2)" "unprognostic (3.06e-2)" "unprognostic (1.36e-1)" "unprognostic (4.62e-3)" "unprognostic (1.48e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-3)" "unprognostic (1.58e-2)" "unprognostic (3.50e-1)" "unprognostic (5.36e-3)" "unprognostic (1.18e-1)" 65.1 12.5 0.1 0.2 0.1 3.2 25.4 0.0 0.1 27.6 0.0 12.6 358.5 11.4 0.0 18.2 9.6 0.1 25.0 0.0 0.0 9.4 32.2 8.2 1.3 0.0 0.0 64.9 239420.0 0.0 13.4 8.1 0.0 17.2 0.0 0.0 25.4 0.9 10.1 11.3 529.2 0.1 0.0 16.9 54.7 8.6 0.0 0.9 8.3 0.0 0.0 7.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 2.4 4.4 0.5 0.0 0.0 0.0 1.9 0.0 21.0 0.0 0.0 0.0 67.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.9 3.8 0.0 2.9 0.6 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 2.9 0.2 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 378.7 0.0 0.4 0.1 11.4 0.0 0.0 0.0 108258.7 0.0 0.3 4.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 0.0 15.5 0.0 0.0 348.9 0.0 0.0 0.0 0.0 9565.7 8.9 0.0 0.1 0.0 60.0 0.1 0.0 0.0 0.0 0.0 36.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 85.4 0.2 PRSS27 "CAPH2, MPN" ENSG00000172382 "Serine protease 27" Q9BQR3 16 2712419-2720551 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 83.5;esophagus: 388.6;vagina: 134.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Horizontal cells: 11.8;Squamous epithelial cells: 9.6;Urothelial cells: 11.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 6.1;SK-BR-3: 24.4;T-47d: 14.6;U-266/70: 5.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB024920, HPA028848" Approved Approved Vesicles "Secreted to digestive system" NA NA 8700000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "CAB024920: , HPA028848: " "unprognostic (2.10e-2)" "unprognostic (2.15e-1)" "unprognostic (3.46e-3)" "unprognostic (5.35e-2)" "unprognostic (5.25e-2)" "unprognostic (2.48e-2)" "unprognostic (2.56e-1)" "unprognostic (3.12e-1)" "unprognostic (4.66e-1)" "unprognostic (1.08e-1)" "unprognostic (3.79e-2)" "unprognostic (4.40e-3)" "unprognostic (4.03e-3)" "unprognostic (2.40e-1)" "unprognostic (2.26e-1)" "unprognostic (2.04e-2)" "unprognostic (1.28e-2)" 1.0 0.4 0.9 0.2 0.9 0.3 1.3 1.0 2.0 83.5 0.6 1.0 0.0 1.0 0.0 388.6 0.7 0.2 0.4 0.8 1.4 1.1 0.6 0.6 0.3 1.2 1.5 0.5 0.8 0.7 1.5 0.1 1.0 1.0 0.0 0.2 52.5 0.4 0.3 3.3 0.6 0.0 1.0 0.6 0.8 2.6 1.2 0.6 0.8 0.0 29.9 0.8 134.2 0.9 0.1 0.3 0.4 2.1 0.3 0.7 6.1 0.0 0.2 0.2 0.2 0.1 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.5 0.1 0.1 0.0 1.0 0.0 0.3 1.2 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.6 0.0 2.0 0.0 1.1 1.4 0.2 0.0 1.0 0.2 0.1 0.2 0.3 0.7 2.8 0.0 24.4 0.6 0.1 14.6 1.8 0.0 0.4 0.0 0.1 0.0 5.2 3.7 0.5 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.9 1.0 2.0 0.8 1.4 1.2 1.5 1.0 1.0 1.2 0.9 1.5 9.6 5.8 0.0 0.5 1.8 2.5 1.3 0.6 5.2 5.1 6.2 1.2 1.5 5.6 1.8 4.2 0.7 0.5 1.2 0.0 1.5 3.3 0.6 1.4 1.8 0.0 0.0 0.4 1.4 0.6 1.4 1.1 1.6 3.8 1.1 0.4 0.7 0.3 11.8 0.8 0.5 0.0 0.3 3.1 1.0 0.3 0.8 1.8 1.9 0.9 2.6 0.0 0.0 0.3 1.1 1.2 0.0 0.2 1.7 0.1 0.7 3.4 6.6 0.0 2.7 1.5 3.0 3.9 9.6 2.4 3.3 1.3 0.6 1.4 11.1 PRSS3 "PRSS4, TRY3, TRY4" ENSG00000010438 "Serine protease 3" P35030 9 33750679-33799231 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Digestion "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 268 "pancreas: 31113.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1022.9;Exocrine glandular cells: 2040.4;Pancreatic endocrine cells: 478.8;Paneth cells: 969.9;Proximal enterocytes: 1127.1" "Group enriched" "Detected in many" 7 "colorectal cancer: 72.8;pancreatic cancer: 104.4;stomach cancer: 43.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 104 "basophil: 158.7" "Lineage enriched" "Detected in many" 104 "granulocytes: 158.7" "Group enriched" "Detected in many" 5 "OE19: 316.6;PC-3: 852.5" "HPA062452, HPA063471" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to digestive system" NA NA 700000000 "Cluster 38: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Endoplasmic reticulum" "HPA062452: AB_2684768, HPA063471: AB_2685017" "unprognostic (6.90e-2)" "unprognostic (2.26e-1)" "unprognostic (1.69e-2)" "prognostic unfavorable (4.30e-4)" "unprognostic (3.18e-1)" "unprognostic (1.64e-1)" "unprognostic (3.29e-2)" "unprognostic (5.89e-3)" "unprognostic (1.38e-1)" "unprognostic (2.06e-3)" "unprognostic (1.10e-2)" "unprognostic (8.94e-2)" "unprognostic (7.75e-4)" "unprognostic (5.46e-3)" "unprognostic (2.13e-1)" "unprognostic (8.79e-2)" "unprognostic (4.96e-1)" 3.8 4.6 23.5 7.2 29.3 0.6 1.7 25.8 35.4 30.8 16.9 87.0 92.6 0.4 0.0 116.2 0.3 22.8 6.3 28.2 25.6 3.7 12.4 0.6 0.7 25.0 24.5 12.9 31113.6 0.0 0.7 1.7 25.7 1.1 77.8 0.3 20.9 0.3 0.5 79.7 105.4 3.1 19.4 0.7 22.8 5.1 25.6 0.8 0.4 0.0 15.2 4.2 56.9 24.7 12.0 13.7 0.7 0.0 0.2 5.9 0.1 33.6 7.7 4.1 1.6 34.3 3.0 0.0 0.2 14.9 0.2 15.0 0.0 31.7 10.1 0.4 0.2 0.0 1.1 0.0 2.7 0.0 0.0 0.2 0.0 10.8 110.2 0.3 68.8 0.2 0.0 0.0 0.0 0.2 0.7 0.4 0.2 316.6 852.5 0.0 0.0 0.0 0.0 1.7 0.3 81.2 0.2 0.0 0.0 0.5 0.0 0.0 78.3 0.0 0.0 12.8 0.0 0.0 0.0 0.1 18.1 0.0 0.1 158.7 0.0 0.0 0.2 1.5 1.2 0.0 0.2 0.4 0.5 0.0 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.3 23.5 29.3 25.8 35.4 28.2 25.6 25.0 24.5 25.7 19.4 25.6 24.7 0.1 0.0 0.0 0.7 1.9 57.1 0.6 1.3 0.0 0.2 0.1 2.8 1.0 47.1 1.2 1.8 0.0 0.0 0.1 1022.9 3.9 43.2 31.4 0.0 0.0 3.2 192.6 0.0 32.8 2040.4 0.0 0.8 39.3 0.0 8.9 0.0 0.7 4.2 0.0 0.0 4.7 146.4 0.0 0.3 12.1 79.7 1.5 1.2 7.2 3.7 5.7 0.0 0.0 3.5 1.2 478.8 969.9 0.7 0.3 12.1 1127.1 14.7 0.1 0.2 0.0 0.0 1.7 0.5 0.9 1.1 134.1 0.1 2.1 0.0 329.0 56.2 PRTG "FLJ25756, IGDCC5" ENSG00000166450 Protogenin Q2VWP7 15 55611544-55743152 "Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 10.4;thyroid gland: 10.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 191.8;Oligodendrocyte precursor cells: 51.8;Rod photoreceptor cells: 62.3" "Cancer enhanced" "Detected in some" "testis cancer: 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "AF22: 148.6;SuSa: 172.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA032138 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Vesicles, Plasma membrane" "HPA032138: AB_10669675" "unprognostic (2.80e-1)" "unprognostic (2.42e-2)" "unprognostic (1.32e-1)" "unprognostic (4.64e-2)" "unprognostic (2.07e-2)" "unprognostic (4.96e-4)" "unprognostic (1.82e-4)" "unprognostic (1.31e-1)" "unprognostic (3.19e-1)" "unprognostic (4.76e-3)" "unprognostic (1.37e-1)" "unprognostic (5.32e-2)" "unprognostic (5.67e-2)" "unprognostic (2.42e-6)" "unprognostic (8.81e-2)" "unprognostic (3.17e-2)" "unprognostic (2.70e-1)" 0.5 1.0 1.7 0.4 2.2 0.1 1.1 2.2 1.1 1.2 1.4 0.5 0.1 3.6 0.5 0.1 1.1 0.3 0.6 1.3 2.8 1.5 0.1 1.7 0.1 3.2 2.4 1.9 0.1 1.9 0.9 2.7 3.7 0.4 0.2 10.4 0.2 0.5 0.6 0.1 0.3 1.3 2.9 0.1 0.5 3.6 2.9 0.0 10.7 0.4 0.1 0.4 0.5 5.0 1.2 3.4 148.6 3.2 0.0 0.1 13.2 1.2 4.5 3.9 5.4 25.8 0.8 0.0 5.4 0.2 5.8 0.0 0.6 0.3 5.2 0.0 6.4 1.0 1.1 9.8 1.1 1.0 0.0 0.5 0.2 1.7 2.7 3.0 2.8 0.3 2.7 0.0 2.3 2.2 0.0 0.0 5.9 0.0 3.0 0.0 22.3 0.0 3.1 0.4 1.8 7.6 1.2 1.9 8.3 172.9 0.7 0.5 0.2 2.1 1.6 0.0 4.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 2.2 2.2 1.1 1.3 2.8 3.2 2.4 3.7 2.9 2.9 5.0 3.2 9.6 20.2 17.6 0.0 0.3 0.0 0.0 0.0 12.4 5.0 4.4 6.0 0.0 2.5 16.5 191.8 19.9 0.1 0.1 0.0 0.0 21.8 2.8 25.5 9.7 0.0 0.0 0.7 0.2 4.1 4.0 3.6 3.1 0.0 2.9 3.6 0.0 1.7 0.0 11.1 0.0 0.0 0.0 0.0 25.3 5.3 0.2 0.0 28.1 0.0 4.4 0.0 51.8 13.6 0.4 0.0 2.6 0.1 0.1 0.0 1.4 0.0 62.3 0.0 5.8 2.4 8.9 12.1 0.0 0.0 6.0 0.1 9.5 0.5 0.1 PRTN3 "ACPA, AGP7, C-ANCA, MBT, P29, PR-3" ENSG00000196415 "Proteinase 3" P24158 19 840999-848175 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 55 "bone marrow: 2098.1" "Cell type enriched" "Detected in some" 17 "Erythroid cells: 26.5" "Cancer enhanced" "Detected in single" "stomach cancer: 1.0" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 8 "neutrophil: 2.0" "Lineage enriched" "Detected in single" 8 "granulocytes: 2.0" "Cell line enriched" "Detected in some" 6 "THP-1: 2054.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005938, CAB017558" Enhanced Approved Vesicles,Cytosol "Secreted to blood" NA NA 390000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol Vesicles "CAB017558: AB_2172317, HPA005938: AB_1855764" "unprognostic (2.81e-2)" "unprognostic (2.10e-1)" "unprognostic (3.83e-3)" "unprognostic (4.20e-1)" "unprognostic (3.31e-2)" "unprognostic (3.34e-1)" "unprognostic (9.98e-3)" "unprognostic (3.67e-2)" "unprognostic (8.62e-6)" "unprognostic (5.31e-2)" "unprognostic (2.00e-1)" "unprognostic (5.14e-2)" 0.8 0.2 0.6 0.0 0.7 2098.1 0.4 0.2 1.3 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.1 0.0 1.6 0.6 0.4 0.3 2.8 11.7 0.4 0.3 0.4 0.1 0.1 0.2 1.3 0.6 0.4 0.3 0.0 0.0 1.6 0.0 0.3 1.3 0.0 0.0 0.2 38.2 0.1 0.2 0.6 7.1 0.4 0.0 0.0 0.0 0.1 0.4 1.2 0.6 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.3 0.0 0.1 0.0 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 343.6 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 2054.4 0.0 0.0 0.0 0.2 0.9 0.0 0.2 0.3 0.0 14.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 9.9 0.6 0.7 0.2 1.3 0.6 0.4 0.3 0.4 0.4 0.2 0.6 0.4 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.8 1.3 0.4 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 26.5 0.4 0.0 0.9 0.9 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 1.5 0.0 0.1 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.2 0.1 0.0 0.1 PRX KIAA1620 ENSG00000105227 Periaxin Q9BXM0 19 40393766-40414793 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 34.6" "Cell type enhanced" "Detected in many" "Adipocytes: 17.8;Breast myoepithelial cells: 23.2;Cardiomyocytes: 15.4;Skeletal myocytes: 30.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Region enriched" "Detected in some" 8 "spinal cord: 114.2" HPA001868 Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Vesicles, Plasma membrane" "HPA001868: AB_2172440" "unprognostic (1.29e-2)" "unprognostic (3.04e-1)" "unprognostic (2.72e-2)" "unprognostic (9.72e-3)" "unprognostic (2.92e-1)" "unprognostic (1.74e-1)" "unprognostic (1.39e-1)" "unprognostic (3.54e-2)" "unprognostic (5.82e-2)" "unprognostic (3.23e-2)" "unprognostic (2.07e-2)" "unprognostic (3.28e-2)" "unprognostic (2.03e-3)" "unprognostic (4.42e-2)" "unprognostic (2.29e-1)" "unprognostic (1.38e-1)" "unprognostic (9.97e-2)" 4.5 4.7 6.2 1.3 6.8 1.6 3.9 5.2 6.5 4.8 2.9 3.6 1.1 4.4 1.0 2.0 4.2 1.8 3.1 4.7 4.4 6.7 1.0 34.6 1.3 5.4 4.9 6.2 3.8 5.9 1.5 5.1 6.7 4.6 0.7 0.8 3.8 3.5 4.9 3.2 2.2 2.0 4.9 2.0 3.7 1.6 5.7 0.7 9.6 5.5 0.8 4.3 3.1 4.1 1.6 2.6 2.1 2.7 1.3 4.4 2.6 1.4 1.5 1.9 1.4 1.0 1.7 0.5 1.6 1.3 1.2 0.9 1.0 0.6 0.7 0.8 0.9 0.3 0.3 0.5 2.1 0.1 2.3 3.3 3.2 1.2 1.1 1.7 1.6 2.9 2.0 0.5 1.0 2.2 1.0 0.6 0.6 3.8 1.7 3.2 1.8 1.5 0.4 1.8 0.2 1.0 2.7 2.3 2.0 0.9 3.2 1.2 1.4 3.8 2.9 1.6 0.8 5.3 5.0 0.7 1.1 1.2 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 6.2 6.8 5.2 6.5 4.7 4.4 5.4 4.9 6.7 4.9 5.7 4.1 17.8 3.2 5.9 0.7 1.4 6.2 2.3 0.3 5.7 0.1 8.1 23.2 15.4 2.8 0.9 1.8 0.0 1.1 1.7 1.0 0.0 0.3 0.1 1.3 1.7 9.2 0.0 0.4 0.6 0.6 0.7 7.0 0.0 3.0 0.0 2.0 6.8 1.3 1.1 0.0 0.5 0.7 2.0 1.6 2.5 0.1 3.4 2.5 3.6 7.5 0.3 3.3 0.0 0.0 0.5 0.5 1.4 4.5 0.9 1.7 1.2 1.9 0.2 0.1 0.0 30.3 6.1 0.3 0.7 5.0 4.1 2.7 1.1 1.3 1.5 1.0 PSAP "GLBA, SAP1, SAP2" ENSG00000197746 Prosaposin P07602 10 71816298-71851325 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid metabolism, Sphingolipid metabolism" "Disease variant, Gangliosidosis, Gaucher disease, Leukodystrophy, Metachromatic leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 2792.8;Kupffer cells: 2427.0;Macrophages: 1916.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 11615.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 5104.0;hTERT-RPE1: 6978.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004426, CAB004647" Supported Supported Vesicles "Intracellular and membrane" NA NA 88000000 "Cluster 7: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Vesicles "CAB004647: AB_425625, HPA004426: AB_1079701" "unprognostic (4.43e-3)" "unprognostic (2.69e-1)" "unprognostic (1.64e-2)" "unprognostic (8.00e-2)" "unprognostic (1.12e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-3)" "unprognostic (2.79e-1)" "unprognostic (3.31e-2)" "unprognostic (3.25e-2)" "unprognostic (2.30e-3)" "unprognostic (2.00e-2)" "unprognostic (3.62e-3)" "unprognostic (6.47e-2)" "unprognostic (4.42e-2)" "unprognostic (2.34e-1)" "unprognostic (2.06e-1)" 1068.6 1192.2 831.4 874.2 946.7 834.2 683.8 873.7 831.7 1073.9 1023.0 667.1 475.6 879.3 951.2 605.5 724.7 1115.6 1413.3 830.5 1081.8 860.4 906.4 1118.6 956.1 957.6 894.0 1106.9 544.7 1167.5 563.5 869.3 885.3 773.9 625.5 665.2 580.9 936.8 1409.5 544.4 487.7 1138.6 1025.9 1045.9 664.0 489.1 1048.8 672.3 875.9 987.5 560.4 941.2 578.3 1325.1 455.9 847.4 540.4 1121.0 5104.0 2910.1 1900.2 799.9 2368.3 620.8 735.9 795.4 1131.9 245.6 1608.1 1321.6 1038.9 964.1 207.5 659.1 434.8 481.4 381.8 288.9 352.3 459.6 1970.7 188.8 1596.0 1871.8 1479.1 625.7 1177.6 6978.9 1128.1 345.8 420.5 1158.1 777.0 294.9 843.8 290.1 249.5 575.4 404.0 172.9 301.3 696.7 730.3 764.4 584.4 515.8 751.1 2248.3 3122.2 700.4 454.4 431.1 1467.0 861.8 610.0 587.1 670.5 1289.0 1038.7 435.4 1375.5 374.4 650.0 863.2 10095.9 1127.5 424.2 11615.6 349.8 466.7 342.9 368.8 3481.1 425.5 370.1 350.6 2890.4 365.8 10148.2 1758.2 422.8 15009.0 831.4 946.7 873.7 831.7 830.5 1081.8 957.6 894.0 885.3 1025.9 1048.8 1325.1 263.2 253.2 339.0 136.8 173.9 228.3 253.4 487.0 108.1 193.8 254.6 158.7 664.1 253.1 318.9 476.3 127.2 891.6 260.2 434.8 70.5 1043.6 19.3 147.0 246.6 311.4 261.9 160.5 86.1 456.1 872.6 623.8 187.6 195.2 398.1 210.8 426.9 509.2 2792.8 333.1 93.7 242.2 343.8 2427.0 779.7 54.1 458.6 1916.9 663.5 105.9 1528.9 495.6 182.3 92.5 117.6 357.7 298.3 551.8 503.0 244.8 370.6 311.6 297.2 164.3 276.1 273.6 263.8 55.2 126.3 137.2 198.0 1073.2 138.9 624.1 228.3 223.9 PSD3 "DKFZp761K1423, EFA6D, EFA6R, HCA67, KIAA0942" ENSG00000156011 "Pleckstrin and Sec7 domain containing 3" Q9NYI0 8 18527303-19084730 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 62.4" "Cell type enhanced" "Detected in many" "Astrocytes: 558.3;Early spermatids: 686.7;Excitatory neurons: 284.7;Oligodendrocyte precursor cells: 488.1;Oligodendrocytes: 584.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 53.8;hTERT-RPE1: 48.0;LHCN-M2: 47.3;U-87 MG: 49.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002455 Enhanced Approved Nucleoplasm,Vesicles,Cytosol Yes No "Cluster 11: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" Cytosol "HPA002455: AB_2666597" "unprognostic (3.87e-2)" "unprognostic (2.52e-2)" "prognostic favorable (7.55e-4)" "prognostic unfavorable (5.76e-5)" "unprognostic (2.56e-1)" "unprognostic (2.66e-2)" "unprognostic (1.04e-2)" "unprognostic (8.84e-2)" "unprognostic (7.27e-2)" "unprognostic (3.39e-1)" "unprognostic (2.50e-3)" "unprognostic (2.13e-1)" "unprognostic (7.18e-3)" "unprognostic (3.71e-2)" "unprognostic (8.77e-2)" "unprognostic (3.83e-2)" "unprognostic (1.45e-1)" 2.4 17.8 24.8 3.1 46.2 1.2 5.9 62.4 46.1 11.9 0.0 6.7 4.8 8.8 3.8 5.3 2.5 7.4 27.5 51.9 4.0 1.9 18.9 4.6 2.5 3.3 10.0 18.0 9.9 18.4 7.3 6.6 1.8 3.9 7.3 19.9 4.1 5.8 1.3 4.4 5.0 5.8 0.0 10.4 9.8 16.4 7.8 2.2 6.1 2.3 3.4 5.8 4.3 17.2 11.0 5.7 25.0 0.1 8.8 53.8 1.3 5.7 8.9 5.1 10.5 3.3 4.3 6.5 3.6 23.8 22.3 0.9 7.3 10.1 9.7 0.0 6.6 0.6 4.6 0.5 15.9 0.2 0.4 14.2 6.2 28.2 4.9 48.0 6.8 1.6 0.8 4.9 47.3 3.7 0.0 1.2 4.9 9.6 14.7 5.2 21.4 3.0 12.7 14.0 10.7 11.8 2.5 1.1 3.8 5.4 0.3 2.6 28.0 15.7 10.8 37.5 5.1 0.4 0.7 14.8 49.5 2.7 5.4 0.7 0.2 0.2 0.1 0.1 0.2 0.3 0.2 0.1 0.1 0.5 0.1 0.1 0.3 0.3 0.2 0.1 0.4 0.1 24.8 46.2 62.4 46.1 51.9 4.0 3.3 10.0 1.8 0.0 7.8 17.2 8.1 3.2 2.7 558.3 3.3 21.9 13.7 26.4 13.6 191.9 14.4 10.7 119.2 7.2 23.9 9.2 118.9 3.2 0.1 48.5 1.9 13.5 686.7 12.5 69.9 8.2 6.1 0.0 284.7 8.7 1.7 44.3 43.8 6.6 0.0 87.2 4.2 42.9 13.1 18.5 121.6 20.0 44.7 16.0 25.9 217.9 33.2 9.0 1.8 148.9 59.7 78.0 0.0 488.1 584.6 27.0 13.5 53.8 0.1 11.2 20.3 0.3 41.0 52.0 13.1 29.3 17.7 16.5 17.7 32.4 9.9 1.1 1.1 114.9 17.2 23.7 PSMA4 "HC9, HsT17706" ENSG00000041357 "Proteasome 20S subunit alpha 4" P25789 15 78540405-78552417 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004973, HPA055466, HPA060613" Supported Supported Nucleoplasm,Vesicles,Cytosol No No 13000000 "Cluster 7: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 32: U-937 - Innate immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" Vesicles "CAB004973: AB_425627, HPA055466: AB_2682824, HPA060613: AB_2684332" "unprognostic (1.80e-1)" "unprognostic (7.08e-3)" "unprognostic (1.31e-1)" "unprognostic (1.62e-1)" "unprognostic (4.71e-2)" "unprognostic (5.35e-2)" "unprognostic (6.26e-3)" "unprognostic (1.09e-1)" "unprognostic (3.28e-2)" "unprognostic (2.08e-3)" "unprognostic (2.75e-3)" "unprognostic (1.26e-1)" "prognostic unfavorable (6.74e-10)" "unprognostic (1.68e-1)" "unprognostic (1.56e-1)" "unprognostic (3.78e-3)" "unprognostic (6.32e-3)" 92.9 105.0 62.5 106.3 64.4 107.6 87.5 66.2 98.8 78.9 65.6 105.1 108.9 89.6 74.5 118.2 71.6 66.0 108.4 64.7 69.1 98.1 152.1 87.9 136.9 67.6 65.5 64.6 67.3 73.4 54.4 85.8 67.5 97.2 109.6 50.3 70.3 64.2 180.6 78.3 101.3 99.3 69.3 115.3 88.5 109.9 65.6 156.5 70.6 121.6 128.7 118.8 81.2 69.9 274.2 386.9 327.7 290.8 202.1 189.5 256.3 250.2 199.9 301.4 320.6 404.9 386.9 590.8 359.7 232.5 337.4 363.9 669.1 271.8 289.1 244.2 465.7 497.6 271.6 330.1 326.9 512.6 294.5 154.6 166.8 255.0 250.9 185.4 330.7 319.1 544.2 225.0 249.6 392.3 347.5 477.4 309.7 315.3 224.5 297.7 432.9 198.9 309.5 469.4 287.6 209.9 401.3 289.5 327.5 402.2 267.8 414.7 265.8 223.7 298.6 249.3 434.2 204.0 517.9 556.2 209.9 756.7 252.6 126.0 251.9 172.9 136.2 403.9 140.3 156.0 142.0 144.7 327.4 119.9 111.7 137.0 112.8 209.4 394.8 185.4 216.8 405.6 62.5 64.4 66.2 98.8 64.7 69.1 67.6 65.5 67.5 69.3 65.6 69.9 119.0 128.2 118.5 17.3 124.1 231.6 269.6 765.7 84.2 57.8 88.5 95.8 163.7 105.8 327.0 121.4 10.4 478.9 128.4 145.3 311.0 296.2 689.4 158.0 183.6 162.5 146.2 153.2 18.0 292.7 450.6 159.9 78.0 126.0 174.2 152.9 114.9 178.9 320.4 72.3 19.6 216.2 506.6 143.2 201.7 399.0 151.0 176.9 133.4 23.4 308.6 63.5 149.3 11.1 21.5 256.0 165.7 147.4 108.0 249.3 195.8 367.2 280.0 39.8 151.2 95.4 241.1 417.1 181.0 106.4 212.8 447.1 128.6 166.7 234.7 258.4 PSMB10 "beta2i, LMP10, MECL1, MGC1665" ENSG00000205220 "Proteasome 20S subunit beta 10" P40306 16 67934506-67936864 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 122.3" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 173.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "REH: 183.4;RPMI-8226: 169.4;THP-1: 171.3;U-266/70: 189.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030224, HPA030225, CAB034384" Enhanced Approved Vesicles,Cytosol NA NA 1400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 14: B-cells - Humoral immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" Cytosol Vesicles "CAB034384: AB_2171876, HPA030224: AB_2673382, HPA030225: AB_10603231" "unprognostic (1.18e-2)" "unprognostic (1.90e-3)" "unprognostic (2.00e-1)" "unprognostic (2.53e-3)" "unprognostic (2.00e-1)" "unprognostic (1.85e-2)" "unprognostic (7.22e-2)" "unprognostic (3.35e-2)" "unprognostic (1.07e-1)" "unprognostic (2.60e-1)" "unprognostic (8.22e-2)" "unprognostic (1.79e-1)" "unprognostic (1.32e-2)" "unprognostic (2.97e-2)" "unprognostic (1.98e-1)" "unprognostic (1.32e-2)" "prognostic favorable (5.44e-4)" 26.3 26.9 5.7 81.8 6.0 71.3 24.9 6.9 8.8 18.9 6.6 51.6 110.5 18.4 5.7 22.8 30.4 31.2 16.2 5.6 8.0 35.1 37.1 42.2 122.3 12.6 7.4 14.6 15.0 6.3 13.2 23.1 8.6 28.9 22.9 0.4 65.1 22.4 6.8 18.1 95.8 14.0 9.5 102.7 62.5 5.3 7.8 61.9 23.6 3.5 37.5 36.4 18.6 11.7 31.8 26.9 0.7 2.2 6.7 17.2 99.6 10.8 42.3 38.5 50.6 13.9 148.5 111.9 23.4 13.2 12.9 47.9 0.0 13.4 2.9 50.3 1.9 39.2 7.6 16.4 65.7 78.5 115.2 26.9 8.4 15.2 1.5 12.1 20.6 32.1 3.6 48.2 9.0 42.6 140.7 84.9 1.0 1.1 10.2 183.4 8.3 169.4 31.6 52.5 0.9 2.3 31.1 67.5 17.2 0.4 14.5 171.3 32.0 21.2 6.6 9.7 15.3 189.8 43.9 88.4 57.1 97.9 47.0 539.5 714.6 571.1 511.7 787.1 376.4 402.6 397.9 437.3 594.8 390.2 326.2 364.6 786.2 588.6 607.4 604.4 495.9 1155.7 5.7 6.0 6.9 8.8 5.6 8.0 12.6 7.4 8.6 9.5 7.8 11.7 24.7 22.4 26.8 4.6 72.9 17.2 14.3 101.2 26.2 1.0 15.8 13.8 1.6 28.6 43.9 18.4 0.0 29.5 66.2 80.8 23.5 58.5 14.0 17.6 20.1 22.8 16.3 32.6 3.4 104.3 30.0 23.4 110.6 12.3 51.9 7.2 37.1 10.2 87.4 0.0 5.0 74.6 52.9 81.9 66.4 35.9 30.1 88.5 48.0 9.4 123.3 3.0 112.3 2.5 7.3 51.2 139.7 21.1 110.5 12.1 173.5 69.4 83.9 1.1 19.7 10.3 26.6 16.4 7.5 24.1 9.9 22.6 93.9 16.9 79.5 24.8 PSMB8 "beta5i, D6S216E, LMP7, PSMB5i, RING10" ENSG00000204264 "Proteasome 20S subunit beta 8" P28062 6 32840717-32844679 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Immunity" "Hydrolase, Protease, Threonine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046995, HPA050327" Enhanced Approved "Vesicles,Cytokinetic bridge" Yes No 2700000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Cytokinetic bridge" "HPA046995: AB_2679896, HPA050327: AB_2681088" "prognostic favorable (5.08e-4)" "unprognostic (4.22e-2)" "unprognostic (2.39e-2)" "prognostic favorable (7.16e-4)" "unprognostic (1.92e-1)" "unprognostic (1.68e-1)" "unprognostic (7.78e-2)" "unprognostic (1.09e-1)" "unprognostic (5.71e-2)" "unprognostic (1.17e-2)" "unprognostic (2.79e-2)" "unprognostic (1.47e-1)" "unprognostic (4.14e-2)" "unprognostic (1.24e-1)" "unprognostic (4.35e-2)" "unprognostic (1.97e-3)" "unprognostic (7.11e-3)" 62.7 76.9 3.3 11.2 3.4 9.8 56.5 3.3 7.3 42.7 3.4 79.9 12.9 41.3 3.2 59.5 41.6 5.8 34.2 3.4 3.5 63.7 99.2 78.2 18.2 4.3 3.4 32.1 29.5 8.2 26.6 4.4 3.7 45.2 20.4 0.7 44.2 6.4 14.4 58.0 93.9 8.9 4.0 150.4 57.0 5.9 3.6 13.5 40.8 0.1 17.2 41.3 48.1 4.1 15.1 3.9 0.3 0.0 5.1 13.1 11.2 4.9 22.9 29.1 39.3 0.0 20.9 45.7 9.4 10.5 25.5 8.1 6.8 16.6 8.0 19.2 0.0 27.6 5.9 0.3 30.3 5.2 7.5 14.9 10.3 12.9 6.8 1.9 18.1 11.8 1.1 8.1 6.1 0.1 12.9 11.7 0.1 0.0 7.3 29.3 1.3 24.1 21.3 4.9 0.8 0.2 8.6 10.4 8.5 0.1 7.0 41.0 4.3 8.8 7.6 7.8 0.6 21.0 15.9 11.2 2.2 27.7 9.0 56.8 70.3 94.6 58.1 88.0 51.2 73.4 49.1 61.1 67.5 71.1 34.8 49.6 90.2 63.0 78.2 58.5 81.2 156.0 3.3 3.4 3.3 7.3 3.4 3.5 4.3 3.4 3.7 4.0 3.6 4.1 237.0 38.5 55.8 2.9 162.0 84.4 64.1 183.7 54.7 1.8 85.3 92.5 8.7 71.4 103.2 62.5 0.0 2.7 211.2 219.9 86.1 219.4 0.6 63.2 74.9 158.5 65.7 45.0 0.1 247.6 18.3 60.7 93.8 81.5 50.7 51.4 114.5 75.0 165.9 6.7 0.5 243.8 120.1 143.5 94.9 1.9 39.1 128.2 56.9 10.3 214.3 39.9 279.1 3.0 0.7 179.6 287.9 30.5 153.2 100.1 319.8 78.9 103.2 3.0 39.5 33.2 56.8 0.4 1.2 60.5 79.6 2.7 181.6 110.9 222.6 121.6 PSME3IP1 "C16orf94, FAM192A, NIP30, PIP30" ENSG00000172775 "Proteasome activator subunit 3 interacting protein 1" Q9GZU8 16 57152466-57186116 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 82.3;Cytotrophoblasts: 56.7;Extravillous trophoblasts: 59.5;Hofbauer cells: 64.6;Syncytiotrophoblasts: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054382, HPA059652" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Vesicles "HPA054382: AB_2682469, HPA059652: AB_2684095" "unprognostic (1.69e-2)" "unprognostic (5.20e-2)" "unprognostic (1.36e-1)" "unprognostic (9.20e-3)" "unprognostic (4.69e-3)" "unprognostic (2.45e-2)" "unprognostic (1.01e-2)" "unprognostic (2.22e-1)" "unprognostic (6.09e-2)" "unprognostic (1.52e-2)" "unprognostic (1.41e-1)" "unprognostic (4.19e-1)" "unprognostic (3.00e-1)" "unprognostic (3.87e-3)" "unprognostic (4.14e-2)" "unprognostic (1.58e-1)" "unprognostic (2.56e-3)" 48.8 50.2 80.5 72.9 93.9 151.0 66.7 85.8 99.0 52.4 83.8 75.4 67.6 54.1 64.7 63.5 54.1 47.3 59.2 78.4 89.7 66.3 62.6 57.6 94.8 91.7 87.3 54.6 55.3 76.7 65.3 56.0 87.3 64.7 87.5 75.2 55.2 50.3 79.0 90.3 76.1 52.3 87.9 93.3 62.6 96.8 85.8 85.0 71.5 66.0 96.5 53.3 56.1 103.7 119.3 148.6 163.6 109.8 70.3 86.2 153.4 138.3 102.3 166.3 107.1 141.3 122.5 179.2 150.6 105.8 84.2 155.9 114.4 137.9 167.1 80.3 92.1 125.0 141.6 148.3 101.0 154.8 170.8 86.6 134.8 158.2 127.4 101.8 121.0 134.4 170.1 56.5 110.8 88.2 169.4 143.2 105.1 88.0 111.3 205.6 236.9 174.5 113.1 96.4 116.3 133.9 250.2 105.2 92.7 113.0 87.1 105.9 120.2 122.0 102.3 90.2 103.7 133.2 113.1 228.6 125.0 109.7 119.6 170.3 78.3 124.1 47.6 93.0 46.8 83.1 45.8 44.7 90.0 77.8 47.0 49.1 107.6 57.1 123.4 62.4 69.2 68.1 80.5 93.9 85.8 99.0 78.4 89.7 91.7 87.3 87.3 87.9 85.8 103.7 16.9 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 82.3 0.0 0.0 0.0 0.0 56.7 10.2 0.0 0.0 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 59.5 16.8 0.0 0.0 0.0 0.0 0.0 0.0 64.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 53.1 1.5 0.0 0.0 0.0 PTAFR ENSG00000169403 "Platelet activating factor receptor" P25105 1 28147166-28193936 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.1;lymphoid tissue: 30.8" "Cell type enhanced" "Detected in many" "granulocytes: 75.4;Hofbauer cells: 71.7;Kupffer cells: 93.0;Langerhans cells: 67.8;Macrophages: 64.5;monocytes: 52.8;Pancreatic endocrine cells: 89.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 256.7;eosinophil: 906.5;neutrophil: 747.1" "Group enriched" "Detected in many" 5 "granulocytes: 906.5;monocytes: 256.7" "Group enriched" "Detected in some" 4 "HBEC3-KT: 36.6;HMC-1: 131.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027543 Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA027543: AB_10610287" "unprognostic (2.22e-2)" "unprognostic (2.59e-2)" "unprognostic (6.73e-2)" "unprognostic (1.24e-1)" "unprognostic (2.75e-1)" "unprognostic (3.74e-2)" "unprognostic (1.07e-1)" "unprognostic (1.72e-1)" "unprognostic (3.35e-1)" "unprognostic (1.23e-1)" "unprognostic (2.39e-1)" "unprognostic (1.60e-1)" "unprognostic (2.79e-2)" "unprognostic (3.52e-1)" "unprognostic (2.59e-2)" "unprognostic (5.48e-2)" "unprognostic (1.38e-2)" 10.4 2.4 4.3 30.8 4.7 41.1 3.4 4.7 5.6 3.4 4.1 5.5 4.1 1.7 1.2 7.2 2.6 7.2 2.0 3.8 5.1 2.7 4.1 17.8 13.5 8.9 6.6 1.3 2.0 1.6 0.6 7.3 7.7 1.5 6.7 0.5 2.3 1.5 0.7 5.4 6.3 7.9 8.1 14.4 3.8 1.3 7.2 3.6 1.9 2.6 18.0 14.4 1.9 11.8 20.1 0.2 0.1 0.4 0.2 0.0 0.5 0.0 0.0 0.7 0.2 0.2 5.7 1.3 0.1 0.1 0.3 13.5 0.5 36.6 0.8 0.4 0.6 7.7 0.2 0.9 0.1 1.9 131.3 0.0 6.0 0.4 0.4 0.0 0.2 0.1 0.5 0.4 0.0 1.3 0.2 19.3 0.6 0.5 0.2 0.3 0.1 0.1 8.7 2.1 0.3 0.1 0.1 18.1 0.2 0.4 0.4 5.4 0.1 0.2 0.7 0.0 0.2 1.2 1.1 5.6 0.1 2.4 0.6 61.7 256.7 906.5 0.6 77.9 1.2 12.5 0.4 0.4 116.1 6.7 0.5 0.7 747.1 0.7 34.1 1.3 1.2 112.4 4.3 4.7 4.7 5.6 3.8 5.1 8.9 6.6 7.7 8.1 7.2 11.8 2.1 6.4 6.7 0.0 4.1 6.5 2.0 37.9 5.2 1.5 0.8 0.5 2.2 1.5 20.9 1.8 2.1 0.6 2.9 0.4 0.0 18.1 0.4 0.5 0.2 7.3 0.0 4.0 0.9 5.1 0.5 1.3 1.1 0.5 75.4 2.0 2.9 1.0 71.7 0.0 0.7 0.0 18.3 93.0 67.8 0.2 0.6 64.5 0.0 15.0 52.8 0.2 0.0 1.5 6.6 89.8 0.6 0.0 0.5 0.6 0.3 0.2 20.2 0.9 0.0 0.6 1.0 2.3 0.7 3.2 2.8 1.5 2.0 0.0 0.4 9.4 PTGR2 "FLJ39091, ZADH1" ENSG00000140043 "Prostaglandin reductase 2" Q8N8N7 14 73851844-73886827 "Enzymes, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 43.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 41.9" HPA001125 Approved Approved Vesicles NA NA 36000 "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA001125: AB_2666207" "unprognostic (3.82e-2)" "unprognostic (2.79e-2)" "unprognostic (6.05e-2)" "unprognostic (3.26e-1)" "unprognostic (2.28e-1)" "unprognostic (1.40e-1)" "unprognostic (1.39e-1)" "unprognostic (1.96e-2)" "unprognostic (2.80e-1)" "unprognostic (8.10e-3)" "unprognostic (6.99e-3)" "unprognostic (5.96e-1)" "prognostic favorable (4.55e-12)" "unprognostic (4.42e-2)" "unprognostic (1.03e-1)" "unprognostic (1.33e-1)" "unprognostic (7.24e-2)" 6.9 12.2 10.4 2.8 11.5 0.9 9.1 11.1 12.1 4.8 11.6 7.2 12.1 4.6 17.2 5.0 12.0 5.2 27.1 9.9 11.7 18.9 19.1 5.6 3.1 11.8 11.9 7.4 5.3 10.6 7.6 2.4 12.1 9.1 5.7 10.7 6.7 5.4 32.8 6.9 8.9 2.6 11.3 3.4 6.2 6.2 10.6 3.0 12.6 32.1 2.6 4.2 4.1 13.9 8.9 11.9 9.6 4.7 7.6 16.3 7.6 3.0 4.1 3.6 5.6 6.8 21.2 0.9 6.8 3.0 8.4 8.8 8.7 6.5 6.6 6.7 4.1 6.2 5.5 3.0 3.8 2.3 2.2 7.7 15.1 5.5 4.4 7.8 1.8 6.1 8.3 1.8 8.2 12.7 6.2 5.9 10.7 11.9 11.6 7.6 3.7 1.5 19.7 8.6 12.7 11.0 7.7 8.1 9.8 9.1 41.9 3.7 2.7 5.3 10.0 3.9 6.6 10.2 4.7 2.8 8.3 5.5 7.2 6.7 1.1 0.9 0.6 0.4 0.6 1.0 1.1 0.5 1.3 1.0 1.8 1.5 0.8 1.3 1.2 1.5 1.1 1.0 10.4 11.5 11.1 12.1 9.9 11.7 11.8 11.9 12.1 11.3 10.6 13.9 4.5 19.2 13.0 10.7 2.9 6.8 12.8 16.7 6.2 8.9 8.4 5.5 43.2 8.6 12.9 18.4 14.6 6.3 2.0 8.6 25.4 11.7 2.4 21.5 5.8 5.2 4.8 4.2 8.0 8.7 2.5 6.1 5.1 7.3 3.8 9.3 3.3 14.3 7.4 33.7 10.3 10.0 10.2 5.5 3.1 2.0 7.2 4.3 8.8 5.6 4.0 22.3 6.2 7.1 20.4 8.7 11.1 6.8 2.9 7.2 24.8 18.4 31.6 20.8 6.6 9.9 6.1 42.1 18.8 3.5 6.7 4.0 2.9 17.3 11.7 7.7 PTGS1 "COX1, PGHS-1, PTGHS" ENSG00000095303 "Prostaglandin-endoperoxide synthase 1" P23219 9 122370530-122395703 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Dioxygenase, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 108.3;skin 1: 152.5;urinary bladder: 175.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 109.9;Glandular and luminal cells: 191.9;granulocytes: 208.0;Hepatic stellate cells: 61.8;Macrophages: 55.3;Suprabasal keratinocytes: 58.7" "Cancer enhanced" "Detected in all" "ovarian cancer: 53.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 28.9" "Group enriched" "Detected in many" 6 "dendritic cells: 20.0;granulocytes: 28.9;monocytes: 13.1" "Cell line enhanced" "Detected in many" "ASC diff: 113.7;ASC TERT1: 89.5;BJ: 115.2;BJ hTERT+: 156.0;HEL: 73.6;HMC-1: 298.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA002834, CAB020315" Enhanced Supported "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 2100000 "Cluster 2: Granulocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Golgi apparatus" Vesicles "CAB020315: , HPA002834: AB_1079711" "unprognostic (4.20e-1)" "unprognostic (6.23e-2)" "unprognostic (1.08e-2)" "unprognostic (2.27e-2)" "unprognostic (5.88e-2)" "unprognostic (2.00e-2)" "unprognostic (1.22e-3)" "unprognostic (3.32e-1)" "unprognostic (2.24e-1)" "unprognostic (3.16e-2)" "unprognostic (1.23e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (4.03e-2)" "unprognostic (1.78e-2)" "unprognostic (2.08e-1)" "prognostic unfavorable (9.35e-4)" 12.8 2.9 3.1 10.5 3.2 9.0 6.7 4.2 4.8 5.8 5.5 108.3 10.8 6.1 2.2 67.3 43.2 9.6 12.6 7.4 5.5 9.3 3.0 11.3 4.6 6.5 5.2 2.0 1.8 2.0 4.8 2.2 6.3 21.1 24.2 0.7 4.3 6.1 2.1 152.5 17.7 16.1 6.7 8.0 20.5 0.9 7.0 2.2 3.2 4.0 11.6 175.0 15.9 11.9 0.3 0.5 0.4 0.0 113.7 89.5 0.0 115.2 156.0 1.0 1.1 0.0 0.2 4.2 5.4 19.7 0.3 7.1 0.4 10.5 0.9 0.0 0.2 73.6 0.6 0.0 32.9 5.2 298.4 46.1 1.2 5.7 0.3 0.0 42.3 0.1 0.1 0.3 2.3 0.0 0.2 6.6 1.6 0.0 0.5 0.3 1.4 8.6 14.7 0.0 0.5 0.6 0.6 9.5 0.2 0.5 0.3 8.4 1.0 0.7 0.6 1.7 0.1 0.3 0.2 0.0 0.4 31.6 0.3 28.9 12.1 23.3 0.0 13.1 0.0 2.4 0.0 0.0 20.0 3.5 0.1 0.0 5.2 2.8 10.2 1.4 0.2 21.9 3.1 3.2 4.2 4.8 7.4 5.5 6.5 5.2 6.3 6.7 7.0 11.9 0.9 0.0 6.6 0.0 5.9 9.9 2.6 7.7 0.0 0.1 1.1 1.4 1.6 4.3 2.2 42.3 0.0 0.1 0.2 0.1 0.0 0.6 0.1 109.9 10.4 24.7 1.8 18.7 0.8 0.5 0.3 10.7 2.0 191.9 208.0 0.1 61.8 0.8 26.1 0.0 0.5 0.6 4.1 15.5 20.7 0.3 1.5 55.3 3.6 16.9 11.7 0.0 7.2 1.0 0.1 0.6 0.6 0.0 0.3 2.8 0.0 0.0 0.8 0.1 0.0 1.4 3.6 0.0 0.2 18.2 58.7 0.4 3.4 0.1 1.0 0.8 PTGS2 COX2 ENSG00000073756 "Prostaglandin-endoperoxide synthase 2" P35354 1 186671791-186680922 "Cancer-related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Dioxygenase, Oxidoreductase, Peroxidase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 116.7;seminal vesicle: 127.4;urinary bladder: 162.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 342.9;Fibroblasts: 270.7;granulocytes: 347.6;Langerhans cells: 305.6;Macrophages: 173.1;Urothelial cells: 151.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 16 "neutrophil: 11.7" "Lineage enriched" "Detected in single" 16 "granulocytes: 11.7" "Cell line enriched" "Detected in many" 4 "BJ hTERT+: 405.5" "Region enhanced" "Detected in many" "hippocampal formation: 15.1" "Low region specificity" "Detected in many" "CAB000113, HPA001335" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" "Endoplasmic reticulum, Vesicles" "CAB000113: , HPA001335: AB_1079712" "unprognostic (1.36e-3)" "unprognostic (9.97e-3)" "unprognostic (3.97e-2)" "unprognostic (3.31e-2)" "unprognostic (1.55e-1)" "unprognostic (1.11e-1)" "unprognostic (5.96e-2)" "unprognostic (9.50e-2)" "unprognostic (9.03e-3)" "unprognostic (2.81e-1)" "unprognostic (3.24e-2)" "unprognostic (3.07e-2)" "prognostic unfavorable (9.79e-4)" "unprognostic (8.04e-3)" "unprognostic (4.38e-2)" "unprognostic (8.89e-2)" "unprognostic (3.74e-2)" 17.0 7.9 1.4 13.9 2.5 116.7 3.0 1.1 4.1 62.2 2.7 14.9 2.6 8.9 0.7 6.9 5.1 31.6 11.7 1.9 1.4 10.2 8.0 34.3 8.9 2.0 1.6 2.6 2.2 5.6 3.1 8.4 1.5 25.0 9.9 0.3 1.2 127.4 0.4 1.6 3.6 12.2 1.9 2.8 14.8 0.2 1.8 5.2 3.2 6.5 0.6 162.5 2.2 2.6 0.0 21.8 0.1 0.0 2.5 2.1 0.0 93.4 405.5 0.6 3.6 15.0 17.2 0.0 0.0 0.1 2.5 12.2 0.0 7.6 1.3 0.0 0.0 0.8 2.2 0.0 13.2 0.0 0.2 0.8 2.7 11.3 28.7 1.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.8 0.0 0.0 0.0 0.0 0.0 5.5 1.5 0.0 1.0 0.0 0.9 2.7 0.0 0.1 1.5 19.3 0.6 13.5 0.6 0.2 0.0 0.0 27.7 0.4 2.3 0.0 0.3 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 11.7 0.0 0.4 0.0 0.0 0.0 1.4 2.5 1.1 4.1 1.9 1.4 2.0 1.6 1.5 1.9 1.8 2.6 5.2 342.9 77.7 0.0 7.4 118.8 59.1 72.8 12.5 0.0 2.6 12.8 2.5 0.0 79.7 0.0 0.0 0.2 4.2 0.3 0.0 0.8 0.2 50.0 9.9 31.1 1.2 3.6 3.8 0.2 0.3 270.7 2.0 98.9 347.6 3.8 13.6 0.2 12.1 0.0 1.0 1.0 8.2 21.0 305.6 0.0 0.0 173.1 35.6 3.7 3.4 0.1 0.0 0.0 0.1 4.9 0.1 0.0 2.0 122.6 0.2 0.3 13.1 0.3 0.0 1.8 12.8 0.1 0.4 3.3 28.4 0.5 10.8 3.7 1.2 151.6 PTK2 "FADK, FAK, FAK1, PPP1R71" ENSG00000169398 "Protein tyrosine kinase 2" Q05397 8 140657900-141002216 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 295.2;Excitatory neurons: 584.9;Oligodendrocyte precursor cells: 353.9;Oligodendrocytes: 791.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001842, CAB004036, HPA029671" Approved Supported "Vesicles,Focal adhesion sites,Cytosol" NA Yes 25000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Focal adhesion sites" "Vesicles, Cytosol" "CAB004036: AB_2269034, HPA001842: AB_1855891, HPA029671: AB_10610288" "prognostic unfavorable (3.21e-4)" "unprognostic (3.86e-2)" "unprognostic (1.95e-1)" "prognostic unfavorable (9.11e-4)" "unprognostic (1.93e-1)" "unprognostic (2.28e-1)" "unprognostic (3.02e-2)" "unprognostic (1.27e-1)" "unprognostic (1.97e-1)" "unprognostic (2.96e-2)" "unprognostic (1.06e-2)" "unprognostic (2.38e-1)" "unprognostic (2.80e-2)" "unprognostic (2.94e-2)" "unprognostic (1.11e-1)" "unprognostic (1.53e-1)" "unprognostic (2.90e-2)" 51.0 40.4 83.8 19.5 115.1 6.7 42.1 62.4 99.9 40.3 51.0 37.2 25.8 37.3 49.7 25.6 34.0 32.1 36.9 84.5 77.3 42.6 30.1 39.4 25.3 79.1 87.6 33.7 32.1 53.1 21.3 74.2 81.0 34.0 35.3 35.5 39.9 41.6 38.7 29.6 29.5 37.6 67.6 22.8 32.8 38.9 86.7 11.9 38.7 39.4 25.8 43.9 34.0 154.5 52.6 81.9 111.0 40.3 45.8 48.8 71.6 50.8 70.0 46.3 45.3 35.9 42.1 31.7 111.7 65.3 65.0 60.3 66.1 116.0 69.6 0.3 30.8 70.1 44.3 50.0 62.5 0.1 31.8 33.4 55.8 58.0 81.0 121.5 139.0 44.0 72.0 0.8 62.9 91.0 0.9 0.7 43.2 113.2 90.3 46.8 60.9 1.5 97.7 117.3 43.9 54.8 79.0 25.0 52.0 97.2 59.2 1.2 84.9 45.2 85.5 54.0 58.1 0.0 0.6 3.4 58.7 0.6 62.9 1.6 3.3 0.0 0.2 1.4 0.0 5.3 0.6 0.0 4.5 6.3 4.4 1.6 1.3 4.7 0.8 6.1 0.2 3.9 83.8 115.1 62.4 99.9 84.5 77.3 79.1 87.6 81.0 67.6 86.7 154.5 71.3 32.1 33.1 295.2 20.6 33.3 70.1 36.3 64.9 55.2 29.3 23.5 29.6 32.9 32.1 55.2 60.5 37.0 8.0 23.1 23.5 27.2 68.4 29.3 43.3 54.3 25.8 8.4 584.9 23.3 53.7 37.2 37.8 46.5 9.5 84.7 37.5 15.7 8.1 67.3 263.6 23.0 30.5 15.2 15.9 38.8 23.9 19.4 24.9 159.3 3.9 40.9 0.0 353.9 791.4 43.1 23.5 21.8 1.7 82.4 29.3 25.6 33.7 55.0 98.6 32.7 128.4 88.9 65.5 42.8 25.9 33.2 3.4 67.0 24.1 87.3 PTPN22 "Lyp, Lyp1, Lyp2, PTPN8" ENSG00000134242 "Protein tyrosine phosphatase non-receptor type 22" Q9Y2R2 1 113813811-113871753 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Immunity" "Hydrolase, Protein phosphatase" "Diabetes mellitus, Disease variant, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.0;lymphoid tissue: 20.3" "Group enriched" "Detected in many" 4 "B-cells: 67.4;dendritic cells: 176.0;NK-cells: 108.1;Plasma cells: 79.6;T-cells: 151.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 69.3;HL-60: 27.7;U-266/70: 29.2;U-698: 37.5;U-937: 28.4" "Region enriched" "Detected in single" 11 "cerebellum: 5.3" "Not detected" "Not detected" "HPA004912, CAB012209, HPA013350" Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Vesicles, Plasma membrane" "CAB012209: , HPA004912: AB_10602069, HPA013350: AB_10601570" "unprognostic (2.25e-2)" "unprognostic (5.31e-3)" "unprognostic (3.48e-1)" "unprognostic (3.33e-4)" "unprognostic (9.14e-2)" "unprognostic (2.47e-3)" "unprognostic (9.60e-2)" "unprognostic (8.14e-2)" "unprognostic (3.71e-1)" "unprognostic (1.82e-1)" "unprognostic (1.62e-1)" "unprognostic (3.02e-1)" "unprognostic (2.75e-6)" "unprognostic (3.19e-1)" "unprognostic (1.10e-1)" "unprognostic (1.61e-1)" "unprognostic (3.22e-2)" 2.0 1.5 0.2 11.5 0.2 38.0 2.3 0.4 0.5 1.8 0.6 4.0 6.4 1.0 1.1 1.7 0.9 4.8 0.6 0.1 0.2 0.6 2.0 7.5 20.3 0.5 0.2 0.6 1.3 0.3 0.3 0.8 0.4 1.0 4.3 0.4 1.3 0.6 0.3 0.9 8.6 1.6 0.2 13.2 5.2 1.4 0.6 20.0 0.7 0.2 13.5 4.2 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.9 0.4 0.0 0.7 0.0 0.4 69.3 0.1 0.2 0.0 0.0 0.0 0.1 0.5 6.5 0.0 10.0 0.0 0.0 0.2 27.7 21.1 5.7 0.0 2.8 0.2 5.1 10.6 17.2 0.1 15.7 10.3 0.2 20.1 15.7 0.0 0.1 0.0 1.2 6.7 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.0 5.0 16.0 0.3 0.4 0.5 29.2 6.6 37.5 11.1 28.4 0.1 15.8 4.8 25.0 17.0 1.3 20.1 9.9 8.4 13.6 8.7 7.4 5.0 12.1 2.4 11.0 0.6 5.2 14.5 7.3 0.2 0.2 0.4 0.5 0.1 0.2 0.5 0.2 0.4 0.2 0.6 0.8 2.2 0.0 6.5 0.7 67.4 2.5 0.2 0.0 1.2 0.7 2.2 2.4 0.8 0.0 0.2 1.8 2.1 0.1 176.0 2.2 0.0 0.1 0.4 0.7 0.5 1.7 0.0 16.6 3.2 0.6 0.3 2.2 12.8 1.0 27.8 0.0 0.4 0.5 7.1 0.0 2.5 1.2 0.0 17.3 26.8 1.0 0.0 26.4 3.6 2.8 14.4 0.0 108.1 0.0 1.7 0.5 0.8 0.0 79.6 0.3 4.3 0.1 2.2 0.5 13.1 0.6 1.4 0.4 0.6 0.3 2.7 0.1 151.2 0.0 2.2 0.3 PTPN23 "DKFZP564F0923, HD-PTP, KIAA1471" ENSG00000076201 "Protein tyrosine phosphatase non-receptor type 23" Q9H3S7 3 47381011-47413435 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Hydrolase, Protein phosphatase" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016845 Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nuclear bodies" Vesicles "HPA016845: AB_1855926" "unprognostic (1.17e-3)" "unprognostic (8.68e-2)" "unprognostic (2.56e-1)" "unprognostic (1.26e-1)" "unprognostic (1.63e-1)" "unprognostic (6.24e-2)" "unprognostic (1.07e-3)" "unprognostic (2.07e-2)" "unprognostic (9.55e-2)" "unprognostic (7.12e-2)" "unprognostic (5.67e-2)" "unprognostic (4.34e-2)" "prognostic favorable (1.82e-4)" "unprognostic (3.05e-2)" "unprognostic (4.40e-1)" "unprognostic (9.53e-2)" "unprognostic (4.68e-2)" 18.5 19.1 6.2 12.6 9.2 14.7 17.4 5.8 10.5 23.3 5.1 16.3 14.3 20.9 7.5 19.0 19.2 8.4 13.2 7.1 7.2 17.5 14.0 18.7 9.1 8.8 7.2 23.5 20.2 23.5 30.9 11.6 8.5 18.7 6.5 8.5 20.0 11.4 30.0 26.4 18.4 8.8 5.5 20.0 16.1 15.6 7.7 8.0 27.1 8.9 7.3 18.5 20.4 14.4 21.5 29.9 16.4 21.4 21.0 16.0 15.8 19.2 18.9 17.5 14.8 25.0 20.7 15.1 17.2 21.9 31.2 19.0 14.3 20.8 8.5 14.3 15.1 21.0 22.2 24.0 23.0 12.3 27.5 21.4 20.9 22.9 23.2 12.4 21.7 12.5 15.9 20.3 19.0 30.2 11.5 10.4 17.5 14.9 20.1 7.2 7.9 18.5 13.2 40.9 8.6 20.6 17.1 35.6 13.6 9.8 20.3 12.0 22.4 26.7 22.2 37.7 27.5 28.8 20.4 8.7 29.0 11.6 19.5 0.8 0.2 0.0 0.1 0.1 0.0 0.2 0.1 0.2 0.0 0.1 0.1 0.1 0.2 0.2 0.0 0.2 0.3 0.3 6.2 9.2 5.8 10.5 7.1 7.2 8.8 7.2 8.5 5.5 7.7 14.4 11.1 9.6 7.0 17.0 8.2 8.0 5.2 6.9 13.6 11.7 9.5 8.0 8.7 8.6 9.5 5.5 14.6 10.6 11.0 15.7 1.9 10.5 2.1 10.3 13.7 12.4 7.3 2.5 9.8 8.9 7.9 9.1 26.5 21.1 2.5 14.9 11.4 12.7 13.9 16.8 12.0 16.3 20.3 10.4 5.5 3.1 19.3 9.5 12.4 7.5 8.7 8.8 6.2 9.5 14.3 13.5 10.4 13.5 15.4 9.3 14.6 9.4 12.6 14.2 6.6 10.2 8.8 13.6 13.3 13.2 10.9 9.3 8.9 9.4 12.8 8.2 PTPN9 MEG2 ENSG00000169410 "Protein tyrosine phosphatase non-receptor type 9" P43378 15 75463251-75579315 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 63.0;Excitatory neurons: 66.1;Inhibitory neurons: 63.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041922 Approved Approved Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA041922: AB_10795269" "unprognostic (9.58e-2)" "unprognostic (1.87e-1)" "unprognostic (1.28e-1)" "unprognostic (2.42e-1)" "unprognostic (1.54e-2)" "unprognostic (6.80e-2)" "unprognostic (7.38e-2)" "unprognostic (5.95e-2)" "unprognostic (3.93e-1)" "unprognostic (3.14e-1)" "unprognostic (9.25e-3)" "unprognostic (6.35e-2)" "prognostic favorable (2.49e-6)" "unprognostic (2.26e-1)" "unprognostic (1.05e-1)" "unprognostic (2.71e-1)" "unprognostic (2.39e-1)" 15.9 12.0 14.8 13.0 16.3 10.8 15.1 11.9 18.8 16.6 11.7 18.0 17.9 16.5 13.3 9.9 16.2 12.1 11.0 16.9 18.4 18.2 14.7 15.8 14.5 18.6 14.4 14.0 10.2 17.9 9.7 19.9 15.1 16.6 19.7 8.9 13.0 21.2 6.4 11.0 20.0 18.0 13.6 13.4 13.5 7.2 17.0 16.1 32.8 13.1 15.0 18.1 13.8 14.5 20.3 24.1 36.7 24.6 26.8 29.3 12.0 29.8 46.2 36.9 33.4 14.5 30.0 32.6 23.3 51.1 29.5 30.0 79.9 34.3 37.0 40.5 19.8 18.4 16.2 15.7 40.2 28.2 27.1 38.4 35.2 29.6 45.9 37.7 31.4 21.3 12.4 11.5 42.1 13.5 20.0 26.3 33.6 18.2 12.1 38.9 18.2 9.1 46.6 32.5 14.4 29.9 42.4 23.3 46.3 34.9 12.1 47.8 36.5 35.2 11.3 23.3 32.2 16.9 18.9 30.0 20.5 41.9 35.3 3.2 2.2 2.3 3.4 3.0 2.8 1.7 2.4 3.0 3.0 1.3 1.0 1.8 0.3 3.9 2.9 2.0 1.6 1.7 14.8 16.3 11.9 18.8 16.9 18.4 18.6 14.4 15.1 13.6 17.0 14.5 12.7 6.4 13.4 63.0 9.2 3.3 8.2 6.6 5.7 12.1 8.0 7.1 3.7 10.0 8.1 11.0 8.4 20.0 7.3 25.0 15.6 10.8 3.0 7.9 19.4 10.0 7.2 13.7 66.1 9.9 4.2 20.6 10.7 11.4 15.2 23.6 17.5 12.6 18.8 3.3 63.2 11.5 6.1 18.9 18.1 4.7 12.5 16.5 7.2 46.9 24.2 5.6 19.6 48.7 19.6 18.2 12.6 27.4 9.7 12.1 24.9 14.0 8.1 17.1 13.1 11.7 20.8 10.6 9.4 6.6 3.3 10.1 13.4 11.6 13.2 13.1 PTPRA "HLPR, HPTPA, LRP, PTPA, PTPRL2, RPTPA" ENSG00000132670 "Protein tyrosine phosphatase receptor type A" P18433 20 2864184-3039076 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029412, CAB034366, HPA069480" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Nucleoplasm "CAB034366: AB_2269058, HPA029412: AB_10602293, HPA069480: AB_2686141" "unprognostic (1.39e-1)" "unprognostic (2.05e-1)" "unprognostic (4.58e-2)" "unprognostic (2.39e-3)" "unprognostic (1.15e-1)" "unprognostic (1.62e-1)" "unprognostic (5.43e-3)" "unprognostic (5.34e-2)" "unprognostic (1.55e-1)" "unprognostic (3.24e-1)" "unprognostic (7.33e-2)" "unprognostic (1.16e-1)" "prognostic favorable (3.29e-6)" "unprognostic (1.25e-1)" "unprognostic (4.02e-1)" "unprognostic (1.60e-2)" "unprognostic (4.19e-1)" 48.8 36.6 83.9 31.9 89.3 39.6 47.4 84.2 96.1 56.4 59.5 41.6 31.0 53.0 36.7 46.1 52.7 43.7 29.5 87.7 83.5 44.2 28.6 45.4 38.9 74.7 81.9 55.8 31.2 81.9 44.8 60.8 78.3 46.3 40.6 61.5 36.3 41.9 16.9 45.8 32.7 52.4 76.3 39.4 34.5 43.4 92.6 59.6 65.5 30.7 44.3 46.6 38.9 81.1 74.0 44.2 124.7 38.4 134.4 243.3 26.5 54.1 105.1 65.5 79.6 53.1 99.5 48.1 41.6 73.1 66.1 77.2 51.0 77.4 73.4 74.7 32.7 68.5 18.3 68.0 48.1 69.5 31.1 109.8 78.2 54.4 56.8 80.3 92.0 67.7 69.9 59.7 65.8 30.4 80.8 78.3 48.3 66.0 35.0 61.0 60.5 60.3 55.1 56.2 68.7 65.7 52.3 87.8 81.4 54.0 55.2 58.7 66.5 58.1 28.6 65.6 48.5 43.4 64.7 62.7 26.9 64.5 55.7 5.7 2.8 4.8 6.1 2.9 4.9 5.3 4.0 4.4 2.1 2.6 4.0 4.8 3.3 4.0 4.3 3.2 4.9 2.3 83.9 89.3 84.2 96.1 87.7 83.5 74.7 81.9 78.3 76.3 92.6 81.1 87.0 22.4 19.2 128.6 46.7 15.8 34.0 15.0 34.7 88.9 49.0 43.9 10.1 54.3 24.5 46.0 31.3 35.3 111.7 39.8 27.4 14.8 17.0 62.0 109.0 39.7 44.3 42.3 138.2 15.8 40.5 67.5 25.0 55.3 22.9 60.3 43.5 33.6 39.4 70.7 136.4 27.9 24.4 37.6 20.4 17.2 60.3 40.1 37.4 52.5 29.9 88.3 110.2 102.5 147.5 16.6 30.2 48.9 58.6 32.9 27.1 23.6 26.6 60.5 39.5 53.3 61.8 68.7 84.1 32.9 17.2 32.7 59.7 41.4 30.4 31.5 PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase receptor type B" P23467 12 70515870-70637440 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 215.9;Endothelial cells: 211.5;Hepatic stellate cells: 504.0;Microglial cells: 164.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 24.3;hTERT-RPE1: 19.7;HUVEC TERT2: 61.4;TIME: 90.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA 14000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: AB_2685911" "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" 26.7 9.4 16.0 4.7 14.1 0.1 18.8 12.3 12.1 12.8 7.1 10.9 7.5 12.3 4.4 6.8 10.8 14.7 23.2 10.1 12.4 22.5 16.7 35.7 3.2 15.9 14.2 4.0 6.2 7.8 4.7 32.6 18.1 6.3 11.1 1.4 3.3 8.0 17.1 4.1 9.3 18.1 12.4 30.0 6.2 2.5 19.0 3.0 14.8 38.8 3.4 7.7 5.3 11.9 4.4 0.3 1.9 0.2 0.0 0.1 0.9 0.9 4.2 2.2 5.2 0.1 3.4 1.7 24.3 0.6 0.4 15.2 0.2 0.7 7.8 1.3 0.7 0.4 1.7 1.1 0.2 0.7 0.0 0.1 0.7 6.1 0.0 19.7 61.4 0.0 3.6 1.0 1.3 0.0 0.1 0.0 2.3 4.4 0.9 0.1 1.6 0.9 11.3 1.8 0.0 0.8 1.6 0.0 3.5 0.4 0.0 1.5 90.3 0.9 0.9 0.4 5.4 1.1 0.9 0.8 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.0 14.1 12.3 12.1 10.1 12.4 15.9 14.2 18.1 12.4 19.0 11.9 215.9 0.0 13.2 2.0 3.1 3.7 0.8 1.0 0.0 7.1 0.9 0.9 12.3 11.5 1.3 3.7 0.0 0.0 2.0 12.8 0.0 1.5 4.6 2.2 0.7 211.5 0.0 16.0 52.5 0.9 0.0 7.3 1.5 4.0 25.2 0.5 504.0 4.7 0.4 5.0 68.8 6.4 0.0 20.0 4.6 3.0 1.2 1.2 5.4 164.9 0.0 0.4 0.0 2.5 2.9 12.2 11.1 0.0 0.1 0.8 3.2 0.1 0.2 0.9 0.0 6.4 5.2 0.7 0.7 0.9 1.6 0.0 1.0 1.8 6.8 0.7 PTPRC "CD45, GP180, LCA, T200" ENSG00000081237 "Protein tyrosine phosphatase receptor type C" P08575 1 198638457-198757476 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Hydrolase, Protein phosphatase" "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 208.6;lymphoid tissue: 329.9" "Cell type enhanced" "Detected in many" "B-cells: 525.2;dendritic cells: 1026.4;Macrophages: 534.1;monocytes: 554.9;NK-cells: 769.3;Plasma cells: 474.2;T-cells: 1049.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 209.9;HEL: 118.0;HL-60: 108.1;JURKAT: 266.4;MOLT-4: 161.1;THP-1: 87.0;U-266/70: 93.7;U-266/84: 91.2;U-698: 123.4;U-937: 94.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000052, HPA000440, CAB002800, CAB056154, CAB068221" Enhanced Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 24000000 "Cluster 14: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" "CAB000052: AB_2314143, CAB002800: AB_2237910, CAB056154: AB_2665572, CAB068221: AB_2665571, HPA000440: AB_611377" "unprognostic (1.51e-2)" "unprognostic (1.24e-2)" "unprognostic (5.10e-3)" "unprognostic (2.33e-3)" "unprognostic (1.30e-1)" "unprognostic (2.40e-3)" "unprognostic (1.62e-1)" "unprognostic (3.17e-2)" "unprognostic (1.25e-1)" "unprognostic (3.18e-2)" "unprognostic (8.08e-2)" "unprognostic (3.95e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (2.31e-1)" "unprognostic (3.43e-2)" "unprognostic (6.41e-2)" "unprognostic (7.06e-2)" 32.8 11.6 3.8 248.5 3.3 208.6 13.9 4.4 4.3 14.9 6.9 26.4 27.4 11.3 5.6 15.1 8.4 45.7 7.3 3.5 5.6 7.0 29.6 68.6 329.9 12.9 8.6 5.7 5.6 4.0 2.9 23.5 11.5 11.6 30.5 2.0 13.8 6.6 4.6 5.7 42.9 25.3 7.9 202.5 37.9 5.5 6.9 306.9 7.0 7.6 251.2 62.1 5.2 14.7 0.4 0.0 0.2 0.2 0.0 0.0 0.8 0.3 0.3 0.1 0.0 0.0 0.1 209.9 0.3 0.7 0.2 0.3 0.0 0.2 0.4 0.6 0.0 118.0 0.2 0.1 0.0 108.1 0.7 0.0 0.0 0.3 0.0 0.4 0.5 266.4 2.4 3.3 0.3 0.1 161.1 65.0 0.5 0.2 0.2 4.6 0.4 0.3 0.1 0.1 1.2 1.8 0.1 0.4 0.5 0.2 0.3 87.0 1.3 0.0 0.8 0.8 0.4 93.7 91.2 123.4 0.1 94.5 0.4 226.1 480.0 521.4 634.4 885.8 541.8 249.0 437.0 618.1 385.8 245.8 489.8 494.1 844.3 506.9 1015.8 57.4 508.6 1340.6 3.8 3.3 4.4 4.3 3.5 5.6 12.9 8.6 11.5 7.9 6.9 14.7 12.6 44.8 62.3 0.7 525.2 15.8 0.9 0.0 4.0 0.3 6.0 9.3 4.6 5.7 14.2 1.8 0.0 0.6 1026.4 1.0 0.0 0.7 2.4 2.3 2.3 15.1 1.2 58.8 0.7 0.0 0.9 17.2 46.9 2.7 246.5 0.1 14.6 6.9 96.0 0.0 1.7 0.4 0.0 334.9 214.5 3.5 1.2 534.1 21.4 201.4 554.9 0.1 769.3 2.5 0.7 0.1 0.8 0.0 474.2 1.1 0.1 2.5 11.7 0.2 6.6 7.4 6.7 0.3 0.6 1.8 15.2 0.8 1049.1 5.4 0.9 0.8 PTPRD "HPTP, PTPD" ENSG00000153707 "Protein tyrosine phosphatase receptor type D" P23468 9 8314246-10612723 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 70.8" "Group enriched" "Detected in many" 12 "Excitatory neurons: 4579.7;Inhibitory neurons: 1152.9;Oligodendrocyte precursor cells: 1170.2;Oligodendrocytes: 3151.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 21.1;HAP1: 4.3;HSkMC: 6.3;RH-30: 8.1;SCLC-21H: 4.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054829 Uncertain Approved Nucleoplasm,Vesicles "Intracellular and membrane" NA NA 20000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles Nucleoplasm "HPA054829: AB_2682618" "unprognostic (4.74e-1)" "unprognostic (4.79e-2)" "unprognostic (1.44e-2)" "unprognostic (7.86e-2)" "unprognostic (2.34e-1)" "unprognostic (9.90e-2)" "unprognostic (1.85e-1)" "unprognostic (1.66e-1)" "unprognostic (1.91e-2)" "unprognostic (2.13e-2)" "unprognostic (7.52e-3)" "unprognostic (2.62e-1)" "prognostic favorable (7.45e-6)" "unprognostic (3.56e-4)" "unprognostic (7.59e-2)" "unprognostic (4.84e-2)" "unprognostic (3.08e-3)" 2.1 0.6 10.8 0.3 24.7 0.1 0.9 12.2 26.2 5.6 0.0 3.3 1.8 2.4 0.2 0.6 2.2 1.0 2.5 14.4 7.2 6.6 3.6 4.6 0.0 14.6 10.1 12.1 1.3 18.7 4.3 5.3 19.1 1.9 2.5 6.4 0.5 0.6 0.9 0.7 5.0 1.0 10.4 0.4 0.9 1.6 17.6 0.7 3.4 0.8 0.0 2.2 3.4 70.8 0.0 0.1 21.1 0.0 0.3 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 2.7 3.6 0.5 0.0 0.0 0.0 0.1 6.3 0.1 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 2.6 0.0 3.4 0.0 3.2 2.3 8.1 0.0 1.8 0.0 4.8 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.8 24.7 12.2 26.2 14.4 7.2 14.6 10.1 19.1 10.4 17.6 70.8 0.5 0.0 3.2 199.2 0.1 0.5 0.4 3.2 6.2 134.2 0.3 0.1 6.5 27.1 1.8 5.5 16.7 0.3 0.0 16.4 0.0 3.6 15.8 0.8 15.0 1.2 35.4 0.0 4579.7 0.0 0.3 15.5 0.5 1.0 0.0 9.2 1.4 13.5 1.3 5.0 1152.9 13.2 0.0 0.8 0.0 6.5 15.8 1.6 0.0 85.3 0.1 36.1 0.0 1170.2 3151.1 0.2 9.2 0.0 2.7 2.1 18.3 26.3 0.2 7.8 0.0 4.0 5.8 2.4 3.2 0.4 0.9 0.3 0.8 6.0 8.7 0.1 PTPRK R-PTP-kappa ENSG00000152894 "Protein tyrosine phosphatase receptor type K" Q15262 6 127968785-128520616 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 889.9;Oligodendrocyte precursor cells: 313.1;Oligodendrocytes: 1278.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 1.6;naive B-cell: 2.9" "Lineage enriched" "Detected in single" 7 "B-cells: 2.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054056, HPA054822" Uncertain Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 13000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" "Vesicles, Plasma membrane" "HPA054056: AB_2682359, HPA054822: AB_2682614" "unprognostic (3.15e-2)" "unprognostic (1.07e-2)" "unprognostic (5.79e-3)" "unprognostic (4.95e-3)" "unprognostic (1.89e-2)" "unprognostic (7.26e-2)" "unprognostic (3.27e-1)" "unprognostic (6.06e-2)" "unprognostic (2.04e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (1.46e-1)" "prognostic favorable (9.33e-5)" "unprognostic (2.10e-1)" "unprognostic (1.55e-1)" "unprognostic (2.59e-1)" "unprognostic (9.32e-2)" 10.7 4.2 13.4 9.7 20.6 0.2 25.6 16.7 18.6 13.5 8.6 27.3 32.8 12.1 8.2 9.7 14.9 32.5 12.4 15.9 14.5 14.9 29.6 19.4 6.9 16.8 16.7 15.1 26.2 10.2 7.0 21.8 17.8 18.9 27.6 4.6 15.3 19.0 5.9 12.2 28.5 15.9 14.5 7.9 30.5 2.2 16.4 10.2 11.7 9.9 8.7 20.9 12.3 29.8 17.3 16.7 10.9 1.0 24.9 31.9 11.0 43.6 86.3 18.4 16.6 28.8 15.0 0.1 13.4 40.7 50.8 49.0 10.2 35.9 26.7 50.3 19.4 0.3 23.6 45.7 29.7 0.0 1.7 23.9 35.4 35.9 49.6 50.8 54.0 14.7 0.0 1.1 49.3 33.6 26.6 0.1 11.9 34.5 22.6 94.8 21.7 3.1 51.1 33.4 43.8 0.1 45.2 55.6 2.7 12.4 14.6 1.1 86.9 30.0 18.4 54.8 42.2 0.7 6.0 0.0 38.1 0.0 31.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 2.9 0.1 0.3 0.0 0.2 0.0 0.0 0.1 0.1 13.4 20.6 16.7 18.6 15.9 14.5 16.8 16.7 17.8 14.5 16.4 29.8 39.2 25.6 33.5 155.7 17.5 63.5 88.1 45.2 60.3 7.3 56.6 26.5 22.2 101.5 44.1 18.4 4.2 24.8 0.8 75.2 0.0 63.2 4.6 30.6 11.5 46.6 43.9 0.0 889.9 61.3 4.1 28.6 77.5 77.5 1.3 13.4 11.4 40.9 6.4 10.1 55.3 44.2 8.2 1.6 8.8 2.7 17.1 2.2 17.8 200.5 1.7 5.1 0.0 313.1 1278.1 124.2 53.8 18.0 1.0 115.8 68.7 13.4 25.9 0.7 59.2 20.1 41.5 11.3 8.9 27.0 38.1 26.8 3.4 14.1 56.6 157.0 PTPRN2 "IA-2beta, ICAAR, KIAA0387, phogrin" ENSG00000155093 "Protein tyrosine phosphatase receptor type N2" Q92932 7 157539056-158587823 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Protein phosphatase, Receptor" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.9;pancreas: 98.1" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 131.1;Excitatory neurons: 439.6;Inhibitory neurons: 433.4;Oligodendrocyte precursor cells: 138.2" "Cancer enhanced" "Detected in all" "prostate cancer: 40.8" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 23.6" "Lineage enriched" "Detected in all" 4 "granulocytes: 23.6" "Cell line enhanced" "Detected in many" "AF22: 45.5;HDLM-2: 42.0;MOLT-4: 22.1;NB-4: 43.0;SCLC-21H: 23.8;SH-SY5Y: 25.4;U-87 MG: 27.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006900, HPA007255, HPA026656" Enhanced Approved Vesicles NA NA 1600000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA006900: AB_1079715, HPA007255: , HPA026656: AB_1855912" "unprognostic (2.42e-1)" "unprognostic (4.17e-2)" "unprognostic (7.82e-2)" "unprognostic (2.69e-2)" "prognostic unfavorable (9.37e-5)" "unprognostic (7.12e-3)" "unprognostic (1.04e-1)" "unprognostic (4.55e-2)" "unprognostic (4.27e-2)" "unprognostic (1.64e-1)" "unprognostic (1.20e-2)" "unprognostic (1.39e-1)" "prognostic favorable (8.68e-4)" "unprognostic (2.60e-2)" "unprognostic (1.48e-1)" "unprognostic (1.43e-3)" "unprognostic (6.16e-2)" 3.8 16.5 29.4 2.7 34.3 1.3 2.9 0.0 49.9 2.1 0.0 7.7 8.3 3.0 4.2 1.9 10.8 7.6 3.1 35.2 22.7 3.9 1.6 4.8 3.4 7.9 3.1 8.7 98.1 1.0 41.0 2.1 3.4 17.3 6.1 9.2 12.9 3.6 1.2 0.8 6.7 2.1 0.1 13.4 40.2 6.2 14.1 1.6 8.7 1.9 2.5 4.2 2.1 20.5 0.1 0.4 45.5 3.6 0.1 0.2 0.1 0.4 0.3 0.0 0.1 0.0 4.0 0.0 1.2 0.5 9.4 0.3 1.0 0.0 0.0 42.0 0.8 0.0 0.0 7.3 1.1 0.0 0.1 2.0 0.8 0.1 0.5 0.3 0.0 3.4 0.1 0.3 0.0 0.7 22.1 43.0 5.7 13.7 3.2 0.0 2.7 0.2 0.2 0.0 23.8 25.4 0.0 0.1 0.0 0.0 0.0 20.9 6.2 9.2 4.3 0.1 1.5 0.3 0.1 0.0 27.7 17.4 6.8 14.1 1.5 2.8 1.3 0.2 0.5 3.5 2.1 1.4 2.1 4.2 2.4 1.4 23.6 2.4 0.0 0.6 5.3 1.3 29.4 34.3 0.0 49.9 35.2 22.7 7.9 3.1 3.4 0.1 14.1 20.5 40.7 3.2 12.9 16.3 18.4 2.3 12.7 1.3 4.0 30.2 1.9 2.2 3.1 10.0 9.1 40.5 10.4 0.4 8.7 5.9 35.2 22.9 51.9 8.7 2.5 26.3 131.1 6.6 439.6 13.1 0.4 13.0 41.8 0.8 19.0 14.1 44.3 0.8 44.5 11.8 433.4 43.3 6.1 7.0 11.3 19.3 12.5 7.9 12.4 27.2 5.7 67.3 15.5 138.2 11.0 7.3 7.0 19.5 5.4 15.0 6.5 3.8 52.6 8.0 26.3 1.4 7.0 62.8 16.3 4.8 1.4 0.7 14.8 32.7 9.7 24.8 PTPRZ1 "phosphacan, PTP18, PTPRZ, PTPZ, RPTPB" ENSG00000106278 "Protein tyrosine phosphatase receptor type Z1" P23471 7 121873089-122062036 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 88.4;skin 1: 31.9" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 2714.3" "Cancer enriched" "Detected in many" 14 "glioma: 175.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "AF22: 425.5;NTERA-2: 126.3;WM-115: 193.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015103 Enhanced Approved Vesicles,Cytosol "Secreted in brain" NA NA 3400000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol Vesicles "HPA015103: AB_1855946" "unprognostic (8.49e-4)" "unprognostic (3.96e-3)" "unprognostic (4.11e-2)" "unprognostic (1.37e-1)" "unprognostic (9.18e-2)" "unprognostic (2.41e-2)" "unprognostic (8.30e-3)" "unprognostic (3.78e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-1)" "unprognostic (9.17e-4)" "unprognostic (1.83e-1)" "unprognostic (8.72e-6)" "unprognostic (2.00e-1)" "unprognostic (2.16e-1)" "unprognostic (8.77e-2)" "prognostic unfavorable (9.36e-4)" 1.6 1.6 66.0 1.2 64.2 0.0 4.0 57.2 88.4 1.8 21.5 4.4 0.6 0.1 0.8 7.9 0.3 0.7 1.3 64.0 64.1 0.1 0.1 1.2 0.0 60.9 62.9 0.7 2.7 0.0 2.3 0.2 62.4 1.0 1.1 19.0 3.4 0.7 0.1 31.9 1.0 1.3 63.7 1.0 13.8 0.3 58.6 0.2 0.1 0.3 2.6 0.9 2.3 72.4 0.1 0.0 425.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.1 0.0 27.7 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 126.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 5.4 15.2 0.1 0.0 0.0 0.1 0.0 0.0 0.7 10.9 5.6 0.0 0.6 0.0 193.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 66.0 64.2 57.2 88.4 64.0 64.1 60.9 62.9 62.4 63.7 58.6 72.4 0.1 0.0 1.5 625.2 0.2 25.2 8.6 82.2 44.9 18.3 5.6 12.2 1.3 0.0 39.7 0.0 4.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.0 0.0 37.7 0.7 0.1 1.3 9.2 0.0 0.0 10.1 0.0 0.0 0.1 65.6 72.0 0.0 0.0 0.0 1.6 0.7 0.3 0.1 19.6 22.5 0.0 90.4 0.0 2714.3 3.6 0.9 0.3 0.0 1.2 1.8 0.0 0.1 16.9 6.6 0.0 1.2 1.7 0.1 1.6 14.8 21.5 0.3 0.2 0.5 0.0 7.8 PUSL1 FLJ90811 ENSG00000169972 "Pseudouridine synthase like 1" Q8N0Z8 1 1308597-1311677 "Predicted intracellular proteins" "tRNA processing" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEK 293: 71.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032057, HPA039999" Uncertain Enhanced Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA032057: AB_10601251, HPA039999: AB_2676792" "unprognostic (2.04e-2)" "unprognostic (1.60e-1)" "unprognostic (2.17e-1)" "unprognostic (1.38e-1)" "unprognostic (1.80e-1)" "unprognostic (3.91e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (7.55e-2)" "unprognostic (4.35e-2)" "unprognostic (1.47e-1)" "unprognostic (2.44e-2)" "unprognostic (3.91e-2)" "prognostic unfavorable (1.62e-5)" "unprognostic (3.05e-1)" "unprognostic (1.48e-1)" "unprognostic (1.45e-1)" "unprognostic (2.44e-1)" 8.1 14.0 6.9 3.3 6.5 4.5 8.7 6.3 9.1 12.7 8.2 9.1 4.5 11.0 4.0 21.0 10.6 2.6 9.8 6.7 6.1 9.4 14.4 8.3 3.9 7.9 6.2 9.1 14.9 3.3 14.9 3.2 6.7 11.7 2.0 2.0 13.7 4.3 7.9 18.1 8.9 2.6 6.2 10.2 10.8 10.9 6.2 4.2 7.5 2.3 3.5 10.4 12.3 7.6 21.9 9.8 9.7 16.6 4.6 7.4 13.1 19.4 10.7 18.8 12.6 33.9 14.1 13.3 15.4 9.6 8.0 17.8 10.8 17.8 3.3 15.1 71.0 18.5 17.7 20.5 17.4 22.2 17.1 7.2 9.2 10.4 7.9 5.1 8.6 18.3 24.1 6.0 8.8 18.2 21.1 28.9 13.2 18.4 42.6 19.2 7.3 32.0 14.8 8.3 44.3 16.2 15.3 45.1 16.1 4.5 12.7 14.6 10.2 12.1 12.5 19.9 18.8 23.4 8.1 57.4 15.0 20.0 7.4 3.7 12.5 6.2 10.2 17.5 10.3 8.5 11.1 8.6 11.7 9.2 7.2 7.3 4.9 9.0 15.9 7.3 14.4 8.4 6.9 6.5 6.3 9.1 6.7 6.1 7.9 6.2 6.7 6.2 6.2 7.6 5.7 0.0 5.3 1.0 8.9 22.0 12.0 19.9 11.4 8.1 16.3 14.0 2.5 8.6 13.5 7.3 6.2 27.0 8.4 15.0 11.7 20.9 11.5 7.7 9.3 6.6 5.3 3.4 2.4 23.1 41.9 9.3 12.2 5.2 7.0 6.3 4.6 10.5 20.9 3.3 2.4 12.5 16.2 8.8 17.4 18.2 8.7 7.4 7.2 0.0 7.7 5.9 10.3 1.5 2.2 26.1 9.9 11.3 14.2 16.8 13.4 18.9 12.0 7.9 0.0 5.2 9.3 17.1 18.5 13.4 19.2 34.5 9.7 18.3 13.2 25.6 PVR "CD155, HVED, Necl-5, NECL5, PVS, Tage4" ENSG00000073008 "PVR cell adhesion molecule" P15151 19 44643798-44666162 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 69.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 4.5;intermediate monocyte: 4.5;myeloid DC: 3.8;non-classical monocyte: 5.5" "Group enriched" "Detected in many" 4 "dendritic cells: 3.8;monocytes: 5.5" "Cell line enhanced" "Detected in many" "TIME: 175.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012568, HPA064739" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" "Secreted - unknown location" NA NA 720000000 "Cluster 7: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Vesicles, Plasma membrane" "HPA012568: AB_1846248, HPA064739: " "unprognostic (2.90e-3)" "prognostic unfavorable (1.29e-4)" "unprognostic (3.36e-1)" "unprognostic (2.34e-1)" "unprognostic (7.89e-2)" "unprognostic (2.45e-3)" "unprognostic (3.06e-2)" "prognostic unfavorable (9.30e-4)" "unprognostic (9.05e-3)" "unprognostic (1.69e-1)" "unprognostic (2.09e-3)" "unprognostic (2.64e-3)" "unprognostic (1.69e-1)" "unprognostic (4.97e-1)" "unprognostic (1.27e-1)" "unprognostic (1.04e-3)" "prognostic unfavorable (2.75e-4)" 13.9 17.5 10.2 7.1 9.1 5.1 9.6 9.0 10.0 8.7 9.3 10.3 12.5 13.9 5.2 8.4 11.8 6.2 28.5 9.0 16.6 13.6 30.7 19.4 2.7 9.7 11.0 12.5 14.0 10.3 17.3 12.5 12.4 9.7 8.8 5.4 9.9 6.4 19.0 7.1 11.1 10.5 7.4 4.6 12.3 5.8 14.9 2.5 10.6 6.2 2.8 9.1 8.5 7.9 58.8 52.1 5.6 25.0 8.6 9.7 7.4 96.7 38.8 40.7 45.8 31.9 28.2 0.1 50.6 43.7 60.2 44.4 24.3 51.1 31.7 7.8 27.1 8.8 40.3 23.3 43.7 4.1 22.2 10.6 28.0 40.9 82.5 49.7 50.7 6.6 4.3 0.5 23.4 7.8 4.2 5.8 12.5 30.1 31.7 0.1 23.2 5.0 111.8 25.5 21.2 22.9 66.3 54.3 14.7 7.2 22.8 12.5 175.3 39.0 52.8 33.7 78.2 0.3 6.3 0.2 35.3 23.4 24.6 0.2 4.5 0.0 0.1 4.5 0.0 0.0 0.0 0.2 3.8 0.0 0.2 0.1 1.1 0.7 5.5 0.5 0.0 1.7 10.2 9.1 9.0 10.0 9.0 16.6 9.7 11.0 12.4 7.4 14.9 7.9 11.1 16.0 25.2 2.3 1.6 3.6 16.0 6.9 4.0 5.7 4.7 3.4 14.4 14.3 12.2 1.8 2.1 2.9 0.2 18.5 3.9 37.9 10.5 5.4 6.3 20.4 13.1 2.1 11.4 35.3 34.8 7.7 13.7 11.6 1.3 6.5 7.9 41.1 8.4 1.7 13.7 11.3 2.0 8.9 7.5 14.3 5.6 6.8 1.8 5.6 17.2 1.8 2.1 6.0 4.6 69.6 18.0 15.8 0.2 14.4 10.8 5.7 2.8 3.4 0.0 23.8 10.4 10.4 1.5 5.8 5.5 1.0 0.9 10.8 12.7 7.4 PXT1 STEPP ENSG00000179165 "Peroxisomal testis enriched protein 1" Q8NFP0 6 36390551-36442854 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 2.3" "Group enriched" "Detected in some" 4 "Spermatocytes: 10.6;Spermatogonia: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "HDLM-2: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA044042 Approved Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "HPA044042: AB_10963537" "unprognostic (1.85e-2)" "unprognostic (1.12e-3)" "unprognostic (9.92e-2)" "unprognostic (5.49e-2)" "unprognostic (4.43e-1)" "unprognostic (9.38e-2)" "unprognostic (2.28e-2)" "unprognostic (2.92e-3)" "unprognostic (4.64e-2)" "unprognostic (1.92e-1)" "unprognostic (5.86e-2)" "unprognostic (3.15e-1)" "unprognostic (4.94e-5)" "unprognostic (2.98e-1)" "unprognostic (2.16e-1)" "unprognostic (7.21e-3)" "unprognostic (2.61e-3)" 0.1 0.0 0.2 0.3 0.1 0.2 0.1 0.2 0.3 0.0 0.1 0.0 0.3 0.1 0.2 0.0 0.1 0.2 0.1 0.2 0.1 0.0 0.0 0.2 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.3 0.1 0.1 0.0 0.1 0.1 0.0 2.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.3 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.2 0.3 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.0 1.0 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.9 0.2 0.4 0.1 0.0 0.0 0.7 0.2 0.1 0.2 1.1 0.4 0.0 0.2 0.0 0.0 0.1 0.0 0.7 0.2 0.0 1.8 0.0 0.7 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 1.2 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.2 10.6 4.9 0.0 0.0 0.3 0.5 0.1 0.2 0.2 QPRT QPRTase ENSG00000103485 "Quinolinate phosphoribosyltransferase" Q15274 16 29663279-29698699 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 119.4;liver: 183.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 404.7;Extravillous trophoblasts: 315.1;Hepatocytes: 367.4;Proximal tubular cells: 598.8;Syncytiotrophoblasts: 215.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 4.2;intermediate monocyte: 5.3;myeloid DC: 5.8;non-classical monocyte: 9.0;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 8 "dendritic cells: 5.8;monocytes: 9.0" "Cell line enhanced" "Detected in many" "EFO-21: 597.1;Hep G2: 258.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011887, HPA076010" Enhanced Approved Vesicles "Intracellular and membrane" NA NA 780000 "Cluster 7: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA011887: AB_2668555, HPA076010: " "prognostic unfavorable (5.10e-5)" "unprognostic (2.00e-1)" "unprognostic (9.48e-2)" "unprognostic (2.88e-1)" "prognostic unfavorable (9.31e-4)" "unprognostic (1.44e-2)" "unprognostic (8.75e-2)" "unprognostic (1.22e-1)" "unprognostic (8.16e-2)" "unprognostic (1.01e-2)" "unprognostic (2.39e-1)" "unprognostic (6.81e-2)" "unprognostic (3.37e-2)" "unprognostic (1.33e-2)" "unprognostic (2.65e-1)" "unprognostic (1.63e-1)" "unprognostic (1.58e-2)" 8.4 89.4 20.6 4.3 20.2 4.8 6.7 25.8 19.8 50.6 19.4 19.2 61.6 26.1 95.2 4.0 43.6 10.2 26.8 18.5 22.2 119.4 183.5 9.2 6.8 28.6 26.6 31.0 34.5 16.2 5.8 27.3 32.4 7.0 15.2 7.5 13.4 26.1 5.1 5.1 30.3 13.7 23.6 17.2 7.1 4.1 22.8 8.2 6.5 1.2 5.2 10.5 11.5 23.3 0.6 1.4 51.8 56.4 8.8 21.6 167.8 6.0 5.2 8.6 11.0 145.9 91.9 2.3 597.1 10.8 10.0 1.0 18.5 0.6 4.5 0.8 16.7 27.1 2.2 258.0 52.5 4.1 10.4 69.8 1.4 4.8 0.2 12.8 0.2 28.2 75.1 2.9 0.4 154.6 17.6 100.3 162.1 1.9 0.2 89.3 16.3 58.5 47.9 4.2 48.6 103.5 0.0 142.1 118.8 85.1 106.5 112.8 0.6 2.5 24.9 0.9 0.5 1.8 4.9 18.8 4.4 10.4 8.1 0.0 4.2 0.3 0.8 5.3 0.9 0.1 0.6 0.7 5.8 0.0 0.1 0.4 0.8 0.4 9.0 3.1 0.9 1.9 20.6 20.2 25.8 19.8 18.5 22.2 28.6 26.6 32.4 23.6 22.8 23.3 3.1 9.6 24.8 5.2 10.1 3.6 11.7 0.5 1.8 3.3 5.0 2.0 43.2 8.6 3.0 64.4 0.0 404.7 5.8 84.5 50.9 1.2 0.0 93.8 49.5 5.5 28.3 10.5 1.3 55.2 315.1 35.8 0.5 81.0 5.1 6.7 9.7 367.4 147.5 6.7 5.6 47.3 0.0 21.2 18.3 0.5 29.2 19.8 42.7 12.2 4.4 20.8 3.1 11.1 0.5 11.5 78.5 27.1 8.7 4.2 161.0 598.8 1.5 5.0 6.6 3.3 16.2 0.5 3.0 0.2 2.0 215.6 5.7 36.5 104.7 8.3 QRICH2 DKFZP434P0316 ENSG00000129646 "Glutamine rich 2" Q9H0J4 17 76274049-76307998 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 18.3" "Cell type enhanced" "Detected in many" "Early spermatids: 33.8;Excitatory neurons: 9.8;Inhibitory neurons: 14.5;Late spermatids: 9.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA052219 Enhanced Approved "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Nuclear membrane, Vesicles" "HPA052219: AB_2681766" "unprognostic (3.11e-2)" "unprognostic (2.44e-3)" "unprognostic (9.11e-3)" "unprognostic (4.42e-3)" "unprognostic (1.35e-1)" "unprognostic (1.32e-2)" "unprognostic (2.09e-1)" "unprognostic (1.89e-1)" "unprognostic (1.83e-1)" "unprognostic (2.61e-1)" "unprognostic (8.82e-4)" "unprognostic (3.64e-1)" "unprognostic (1.39e-1)" "unprognostic (6.97e-2)" "unprognostic (7.15e-2)" "unprognostic (1.05e-1)" "unprognostic (1.71e-3)" 1.0 0.7 3.9 0.7 3.7 1.7 1.1 6.3 7.0 1.8 2.5 1.6 0.3 1.1 0.7 2.1 1.6 0.3 1.6 3.6 3.6 2.0 2.3 1.7 0.6 6.3 3.8 1.3 1.9 0.6 1.8 1.0 6.4 2.1 0.6 2.7 3.6 0.5 1.2 1.3 1.1 0.4 3.2 1.1 1.2 18.3 4.5 0.5 4.4 0.5 0.5 1.0 1.7 4.4 0.8 1.6 2.9 3.3 1.5 1.4 1.4 1.4 0.3 1.0 0.3 0.5 0.3 4.2 0.5 0.9 0.8 0.3 4.0 0.7 1.3 1.1 2.2 0.4 1.2 3.7 0.8 0.6 1.9 1.3 0.6 1.2 0.1 2.0 1.3 1.2 2.3 0.8 0.3 2.5 2.3 0.5 1.2 1.0 3.2 4.9 2.5 0.1 0.5 1.5 2.7 2.7 0.7 0.4 1.7 2.9 1.2 1.7 1.2 0.8 3.1 4.1 1.7 1.1 1.1 0.4 0.9 2.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 3.7 6.3 7.0 3.6 3.6 6.3 3.8 6.4 3.2 4.5 4.4 0.8 0.0 0.0 6.5 0.8 0.1 0.4 0.2 0.0 0.7 1.5 1.8 1.7 5.7 0.3 1.8 0.0 0.7 0.1 0.7 0.0 0.9 33.8 1.4 0.9 0.9 0.0 0.4 9.8 0.0 1.1 0.3 2.0 1.6 0.0 3.7 0.0 0.5 0.2 1.7 14.5 0.5 0.0 0.6 0.4 9.1 0.9 0.3 1.8 5.6 0.6 1.9 1.0 5.5 5.4 0.4 0.2 0.7 0.9 0.3 0.2 0.8 1.1 2.3 0.0 0.9 1.0 5.0 1.5 0.6 0.3 0.4 0.4 0.1 0.6 0.3 QRSL1 "DKFZP564C1278, FLJ10989, FLJ12189, FLJ13447, GatA" ENSG00000130348 "Glutaminyl-tRNA amidotransferase subunit QRSL1" Q9H0R6 6 106629578-106668417 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "memory B-cell: 86.4;naive B-cell: 71.0" "Lineage enriched" "Detected in all" 7 "B-cells: 86.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029585, HPA029587" Approved Approved Vesicles,Centrosome NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" Vesicles Centrosome "HPA029585: AB_10599823, HPA029587: AB_10602311" "unprognostic (1.86e-3)" "unprognostic (5.58e-2)" "unprognostic (6.19e-3)" "unprognostic (3.45e-1)" "unprognostic (2.11e-3)" "unprognostic (1.31e-2)" "prognostic unfavorable (7.97e-5)" "unprognostic (8.36e-2)" "unprognostic (1.70e-1)" "unprognostic (1.06e-1)" "unprognostic (4.03e-2)" "unprognostic (1.66e-1)" "prognostic favorable (3.83e-4)" "unprognostic (2.06e-1)" "unprognostic (2.09e-1)" "unprognostic (2.04e-1)" "unprognostic (3.46e-1)" 5.0 5.7 4.0 8.6 5.2 6.4 7.4 4.7 5.0 4.8 5.8 8.2 7.8 6.3 6.1 5.7 5.4 4.8 10.1 4.1 4.5 9.3 7.8 4.6 15.9 4.6 4.5 5.6 6.0 9.4 4.3 5.7 5.0 5.3 9.1 8.4 6.1 5.6 19.4 5.9 8.9 5.8 4.1 10.5 6.7 6.6 4.5 8.2 9.2 21.3 15.5 5.7 4.9 7.4 9.0 9.1 12.3 17.8 7.8 9.7 17.3 10.0 10.2 13.1 13.0 10.7 7.1 29.7 8.9 11.2 13.5 15.5 18.6 12.1 16.4 14.2 14.1 14.5 9.7 11.1 12.2 33.2 12.5 9.6 18.6 14.0 20.6 9.9 9.5 18.4 26.8 9.4 11.0 10.1 10.7 16.1 12.9 15.6 10.5 28.9 15.8 7.5 14.3 10.2 10.7 11.0 8.0 18.4 15.3 10.7 12.1 25.3 9.3 9.2 7.6 10.0 15.7 5.4 8.3 17.2 12.6 22.1 14.0 5.0 6.4 1.0 6.4 9.6 6.3 86.4 7.1 5.6 10.7 71.0 6.6 6.4 1.6 7.0 13.0 8.5 8.5 5.7 4.0 5.2 4.7 5.0 4.1 4.5 4.6 4.5 5.0 4.1 4.5 7.4 9.0 19.2 12.5 20.2 64.6 4.0 8.4 12.8 6.2 14.9 10.3 6.1 24.8 7.2 9.3 11.0 16.7 21.5 12.3 11.0 17.6 15.4 15.5 28.2 12.0 10.8 17.4 13.7 14.6 18.4 23.0 9.9 15.3 14.8 18.9 15.3 8.2 14.6 12.9 3.3 18.9 11.2 14.2 12.4 6.1 8.4 8.4 10.0 8.8 12.2 18.3 9.9 19.6 22.6 26.5 14.2 8.3 9.1 13.2 9.3 12.2 19.5 19.9 19.1 0.0 10.0 10.0 25.6 14.2 12.2 5.4 12.3 14.3 21.1 18.7 8.9 QSOX1 QSCN6 ENSG00000116260 "Quiescin sulfhydryl oxidase 1" O00391 1 180154869-180204030 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Extravillous trophoblasts: 1616.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 1918.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056243 Supported "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 2600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus" Vesicles "HPA056243: AB_2683077" "unprognostic (1.13e-1)" "unprognostic (2.62e-3)" "unprognostic (2.46e-1)" "unprognostic (2.49e-2)" "unprognostic (2.00e-2)" "unprognostic (2.73e-1)" "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (3.94e-1)" "unprognostic (3.12e-2)" "unprognostic (5.07e-2)" "unprognostic (2.80e-3)" "prognostic unfavorable (1.86e-5)" "unprognostic (3.25e-1)" "unprognostic (2.14e-1)" "unprognostic (3.53e-2)" "unprognostic (1.40e-1)" 84.8 84.9 35.8 52.1 39.4 115.5 53.2 42.7 47.3 81.7 41.1 100.1 67.5 75.2 70.2 178.4 82.3 150.3 244.9 41.5 43.4 73.8 81.7 200.0 16.3 50.0 40.7 196.1 136.3 21.0 60.2 158.9 43.2 92.3 80.9 15.2 105.6 57.5 91.2 58.6 85.7 60.0 44.0 61.9 178.3 172.9 42.6 12.1 31.9 46.0 19.6 174.1 108.7 57.7 441.4 62.0 14.8 181.0 179.1 367.8 712.5 456.5 456.6 381.6 267.1 7.3 137.7 6.8 276.7 367.8 52.6 93.7 17.6 123.5 185.0 26.4 28.0 14.1 33.6 19.4 1918.6 48.6 129.2 197.9 55.5 408.0 484.3 499.9 569.4 32.1 20.2 66.3 255.3 76.4 10.4 89.7 49.4 302.6 174.6 19.7 33.0 11.8 63.1 123.6 51.9 52.6 133.8 179.8 91.9 32.2 33.0 226.3 678.3 473.8 187.5 322.0 392.9 48.3 84.4 12.2 180.9 153.9 146.0 16.2 53.1 20.6 14.0 29.9 10.2 5.4 9.1 9.6 39.2 3.2 8.1 8.0 40.2 16.9 28.6 8.0 11.5 28.6 35.8 39.4 42.7 47.3 41.5 43.4 50.0 40.7 43.2 44.0 42.6 57.7 36.6 57.7 101.6 8.5 7.7 13.8 27.4 81.2 7.4 11.5 86.2 47.9 48.3 51.5 112.5 71.7 25.0 19.5 10.7 138.1 0.0 230.4 49.2 49.2 19.4 41.7 46.2 6.9 17.2 130.1 1616.7 78.0 136.6 80.4 25.4 27.1 89.3 4.3 68.6 6.7 17.0 185.7 132.2 45.2 35.3 20.1 177.7 48.9 44.4 8.4 49.7 53.5 10.3 24.6 23.9 249.8 165.6 71.1 12.8 35.7 9.0 9.1 47.8 6.7 32.9 13.6 31.3 30.2 32.7 10.2 9.9 154.3 13.9 13.9 89.9 68.0 RAB11A YL8 ENSG00000103769 "RAB11A, member RAS oncogene family" P62491 15 65726054-65891989 "Predicted intracellular proteins" "Cell cycle, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 969.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013097, HPA051697, HPA060686" Approved Enhanced "Vesicles,Centriolar satellite" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Vesicles, Centriolar satellite" "CAB013097: AB_2533987, HPA051697: AB_2732569, HPA060686: AB_2684342" "unprognostic (4.15e-2)" "unprognostic (5.86e-2)" "unprognostic (1.22e-1)" "unprognostic (8.74e-3)" "unprognostic (6.85e-2)" "unprognostic (6.07e-2)" "unprognostic (3.17e-2)" "unprognostic (7.12e-2)" "unprognostic (8.60e-2)" "unprognostic (4.83e-2)" "prognostic unfavorable (4.37e-4)" "unprognostic (4.29e-2)" "prognostic favorable (1.46e-5)" "unprognostic (9.93e-2)" "unprognostic (1.83e-2)" "unprognostic (5.23e-3)" "unprognostic (1.21e-1)" 140.0 231.6 79.7 123.9 86.4 126.0 150.1 83.4 105.0 159.3 78.5 223.8 139.8 117.4 130.9 480.0 146.1 185.1 156.3 86.1 97.4 162.9 124.1 148.1 141.2 87.0 83.0 104.9 107.6 192.5 106.8 214.4 101.3 150.3 224.2 99.0 195.1 126.2 119.6 288.5 158.9 149.2 87.2 183.9 216.2 201.8 86.0 143.6 155.3 109.6 246.0 269.8 232.2 86.7 285.2 330.3 330.1 240.8 294.7 275.0 431.1 297.0 300.4 264.4 313.0 305.8 497.4 370.7 295.8 342.6 262.3 429.0 525.0 393.2 248.2 243.7 314.9 445.3 219.9 274.1 224.7 211.5 254.0 282.8 438.1 260.2 214.7 281.7 595.2 197.8 364.5 214.3 378.1 283.7 209.9 167.3 275.9 1057.4 185.9 176.3 250.5 346.3 716.1 734.7 237.4 251.9 214.0 335.6 286.5 387.8 445.0 243.0 453.7 208.4 296.4 203.1 267.8 112.2 289.5 288.8 193.7 353.5 228.8 183.5 154.8 235.2 56.7 133.9 58.8 78.8 85.3 68.6 137.1 64.1 78.9 63.6 232.8 71.3 154.6 87.6 109.5 340.2 79.7 86.4 83.4 105.0 86.1 97.4 87.0 83.0 101.3 87.2 86.0 86.7 155.7 57.7 57.8 15.3 90.2 192.2 180.2 375.2 134.3 42.3 107.5 69.6 89.5 105.8 245.4 187.6 33.3 326.4 76.0 313.4 346.3 360.6 413.1 119.3 72.7 260.7 206.2 91.1 31.3 337.0 340.4 96.9 149.9 194.5 74.9 75.9 235.2 88.4 239.2 57.2 27.7 227.4 244.1 114.8 214.2 80.9 97.3 148.1 186.7 42.2 217.8 137.9 65.9 25.6 21.9 391.1 277.0 86.5 72.1 187.6 205.8 271.5 240.0 36.1 46.0 45.2 161.5 407.5 95.3 225.5 284.4 969.3 96.6 97.6 209.2 360.8 RAB11B H-YPT3 ENSG00000185236 "RAB11B, member RAS oncogene family" Q15907 19 8389981-8404434 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 334.5" "Low region specificity" "Detected in all" HPA054396 Approved "Vesicles,Centriolar satellite" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" "Vesicles, Centriolar satellite" "HPA054396: AB_2682474" "unprognostic (5.81e-3)" "prognostic favorable (2.08e-4)" "unprognostic (1.13e-2)" "unprognostic (1.70e-2)" "unprognostic (1.59e-1)" "unprognostic (1.61e-3)" "unprognostic (2.37e-1)" "unprognostic (1.23e-1)" "unprognostic (2.51e-1)" "unprognostic (4.78e-2)" "prognostic favorable (7.58e-5)" "unprognostic (1.23e-1)" "prognostic favorable (2.06e-4)" "unprognostic (3.66e-1)" "unprognostic (3.87e-1)" "unprognostic (8.85e-2)" "unprognostic (3.29e-3)" 102.1 96.7 97.6 59.2 113.2 68.7 113.8 118.5 131.4 105.3 67.4 99.1 76.5 101.3 23.0 95.2 97.3 51.2 167.9 91.7 102.0 129.3 133.8 98.2 58.8 130.9 121.8 107.6 129.7 49.0 115.7 53.9 127.7 111.7 23.4 38.2 104.3 49.3 119.6 101.8 97.2 27.8 108.1 118.7 118.0 64.5 120.4 44.1 210.0 36.6 28.2 99.5 94.2 127.3 93.1 115.3 83.1 75.9 43.7 39.9 64.8 54.6 36.8 39.5 42.0 79.4 74.3 54.1 147.7 47.3 53.1 70.8 29.4 78.7 13.1 109.3 142.4 57.5 97.8 98.0 42.4 67.6 102.6 59.5 49.1 44.6 29.6 51.2 50.1 71.7 62.4 137.2 42.2 92.8 116.7 334.5 117.9 44.6 111.3 75.2 56.2 91.0 43.6 130.1 91.4 118.7 67.7 53.8 71.5 33.8 67.9 75.0 98.0 146.2 85.4 114.0 86.2 145.3 101.7 64.1 109.4 75.3 100.6 47.6 44.4 100.7 44.7 45.5 30.6 39.6 40.3 46.8 45.4 41.3 38.1 36.6 65.7 53.7 55.2 59.1 43.0 39.6 97.6 113.2 118.5 131.4 91.7 102.0 130.9 121.8 127.7 108.1 120.4 127.3 74.0 19.2 25.7 21.2 68.3 62.1 86.2 115.1 75.7 60.1 85.0 79.8 18.1 71.4 59.5 95.6 14.6 152.2 52.4 148.4 127.2 93.8 44.3 58.2 43.2 70.7 114.7 63.1 15.1 94.9 166.7 71.3 99.4 51.0 29.9 56.5 76.1 62.2 109.6 67.3 18.7 112.4 118.0 62.8 52.7 38.0 86.3 62.6 71.2 15.9 76.9 104.1 59.8 8.5 41.3 82.3 154.7 76.3 78.0 81.1 135.5 113.9 59.3 36.0 92.1 50.1 121.0 64.5 38.7 69.8 69.3 209.9 63.3 46.4 92.8 104.6 RAB11FIP1 "FLJ22524, FLJ22622, Rab11-FIP1, RCP" ENSG00000156675 "RAB11 family interacting protein 1" Q6WKZ4 8 37858618-37899497 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 798.0;Endometrial ciliated cells: 622.9;Glandular and luminal cells: 969.7;Urothelial cells: 613.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 101.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 101.9" "Cell line enhanced" "Detected in many" "K-562: 73.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB017037, HPA023904, HPA024010, HPA025960" Enhanced Enhanced Vesicles No No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Vesicles "CAB017037: , HPA023904: AB_1855990, HPA024010: AB_1855991, HPA025960: AB_1855992" "unprognostic (1.62e-2)" "unprognostic (3.47e-2)" "unprognostic (3.22e-3)" "unprognostic (2.87e-1)" "unprognostic (1.06e-1)" "prognostic favorable (6.61e-4)" "unprognostic (4.32e-1)" "unprognostic (4.50e-3)" "unprognostic (1.58e-1)" "unprognostic (4.72e-2)" "unprognostic (2.82e-3)" "unprognostic (2.73e-2)" "prognostic favorable (1.14e-6)" "unprognostic (4.94e-2)" "unprognostic (8.41e-2)" "unprognostic (9.99e-2)" "unprognostic (1.50e-1)" 7.5 5.7 3.8 17.7 2.7 58.5 21.8 3.8 3.8 14.5 39.3 40.7 41.3 5.9 14.8 47.1 16.9 21.7 12.0 4.4 4.3 13.7 7.2 74.0 17.2 3.4 2.7 4.6 42.5 12.0 8.6 25.8 2.1 8.7 47.0 6.1 23.8 13.5 4.6 18.9 53.5 7.1 2.3 12.0 45.5 6.4 4.0 15.4 13.0 2.7 31.1 23.6 14.9 2.2 41.8 18.1 1.9 8.0 0.4 0.1 54.1 4.2 6.6 7.5 9.6 40.6 23.2 17.0 12.7 5.1 0.4 31.6 14.5 9.4 11.3 44.2 13.5 3.3 9.0 11.9 20.9 7.3 36.3 4.8 12.2 2.8 7.9 11.1 0.1 22.2 73.1 8.2 3.8 9.9 12.4 10.7 12.0 40.9 5.3 3.9 9.7 13.2 39.4 42.2 7.4 8.5 10.6 52.3 13.0 36.8 35.2 14.0 0.6 0.2 23.1 0.6 0.7 16.5 20.7 4.5 0.3 9.8 5.7 24.0 20.5 38.1 4.4 9.4 9.9 6.0 3.2 3.1 18.3 3.8 2.0 2.2 101.9 10.9 20.2 11.0 7.7 10.7 3.8 2.7 3.8 3.8 4.4 4.3 3.4 2.7 2.1 2.3 4.0 2.2 7.6 798.0 112.9 1.0 128.5 15.9 113.5 49.5 24.5 5.4 113.6 58.5 15.8 84.4 228.0 64.4 16.7 44.9 123.6 385.5 15.6 170.2 0.9 622.9 71.4 25.3 243.7 3.8 7.9 248.9 8.1 28.7 272.7 969.7 30.4 2.8 32.2 15.3 32.1 6.7 8.6 312.3 95.6 59.1 174.7 1.8 1.8 121.1 16.0 2.8 95.2 18.6 120.5 0.0 1.0 364.6 299.1 1.5 48.2 192.7 331.9 16.5 348.8 21.0 6.6 9.0 23.3 2.4 5.2 124.2 30.5 96.0 83.8 2.8 256.6 613.9 RAB11FIP2 "KIAA0941, nRip11, Rab11-FIP2" ENSG00000107560 "RAB11 family interacting protein 2" Q7L804 10 118004916-118046941 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 82.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037726 Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 68: Epididymis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" Vesicles Nucleoplasm "HPA037726: AB_10672390" "unprognostic (1.97e-1)" "unprognostic (1.68e-2)" "unprognostic (3.61e-1)" "unprognostic (4.45e-2)" "unprognostic (1.30e-1)" "unprognostic (5.58e-2)" "unprognostic (2.17e-2)" "unprognostic (3.34e-2)" "unprognostic (1.83e-2)" "unprognostic (2.15e-1)" "unprognostic (2.06e-1)" "unprognostic (1.47e-1)" "prognostic favorable (9.69e-5)" "unprognostic (1.17e-1)" "unprognostic (1.56e-1)" "unprognostic (1.90e-1)" "unprognostic (2.17e-1)" 8.6 6.6 5.2 6.6 7.0 13.8 6.9 4.8 8.5 10.2 2.4 8.2 3.6 18.8 28.5 6.3 11.8 8.3 6.1 7.1 3.4 12.2 5.4 7.6 6.9 2.8 4.6 9.9 5.6 6.3 4.3 8.2 2.2 10.8 4.9 10.3 4.8 24.7 5.0 5.9 5.5 19.5 3.7 6.6 17.2 7.8 5.3 6.2 11.4 7.5 5.5 7.6 6.2 6.1 7.1 8.8 7.3 9.3 11.9 15.0 7.8 13.8 15.8 8.3 8.6 7.4 7.4 14.5 10.8 14.0 6.1 4.8 10.1 6.1 12.8 3.8 10.9 5.1 9.1 5.1 17.2 9.7 5.5 14.8 11.3 11.6 25.4 11.0 5.1 9.3 3.9 12.1 10.9 2.5 7.5 7.3 6.2 3.1 6.2 6.4 26.0 4.9 12.4 5.6 1.7 13.5 9.8 3.9 17.3 8.7 3.0 8.9 7.7 11.2 8.9 13.3 13.8 8.9 7.8 9.4 11.5 16.4 7.0 0.2 0.2 0.2 0.2 0.1 0.2 0.3 0.2 0.2 0.1 0.4 0.4 0.2 0.3 0.1 0.1 0.5 0.1 0.0 5.2 7.0 4.8 8.5 7.1 3.4 2.8 4.6 2.2 3.7 5.3 6.1 16.7 57.7 31.5 79.7 17.7 10.3 8.8 4.4 12.5 28.1 10.1 10.7 25.8 24.3 6.0 42.3 29.2 11.6 15.1 5.5 7.9 12.6 16.5 13.1 31.0 14.1 14.5 17.4 63.8 18.7 7.9 29.1 14.8 15.7 3.8 28.0 11.4 8.6 11.4 38.7 57.9 6.6 4.1 23.0 12.2 6.6 33.5 16.2 23.2 34.7 19.4 26.0 15.5 53.8 82.9 16.6 4.7 28.6 17.0 11.1 5.4 18.1 7.3 31.4 26.3 34.0 25.8 14.9 21.2 9.2 9.5 5.2 12.9 19.2 6.5 6.4 RAB11FIP3 "eferin, KIAA0665, Rab11-FIP3" ENSG00000090565 "RAB11 family interacting protein 3" O75154 16 425649-523011 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 151.1" "Cell type enriched" "Detected in many" 5 "Proximal tubular cells: 384.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028088, HPA028631, HPA030086" Enhanced Enhanced "Nucleoplasm,Vesicles,Cytokinetic bridge,Centriolar satellite,Mitochondria" Yes No "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Centriolar satellite" "Nucleoplasm, Cytokinetic bridge, Mitochondria" "HPA028088: AB_10601672, HPA028631: AB_10601853, HPA030086: AB_10669596" "unprognostic (6.65e-2)" "unprognostic (1.84e-2)" "unprognostic (1.51e-1)" "prognostic favorable (1.22e-4)" "unprognostic (2.87e-2)" "unprognostic (1.85e-1)" "prognostic unfavorable (9.87e-5)" "unprognostic (6.71e-2)" "unprognostic (4.74e-1)" "unprognostic (9.66e-2)" "prognostic favorable (3.16e-5)" "unprognostic (1.12e-1)" "prognostic favorable (7.99e-4)" "unprognostic (1.39e-1)" "unprognostic (1.77e-1)" "unprognostic (1.58e-1)" "unprognostic (1.44e-1)" 27.9 32.3 18.0 5.3 18.9 7.0 19.5 21.3 22.6 29.6 7.6 35.1 9.0 31.3 5.5 12.3 27.5 7.4 31.4 21.7 14.0 151.1 37.3 25.2 5.8 14.4 15.8 33.8 47.4 15.9 41.5 6.5 15.2 29.9 3.1 6.1 19.3 7.8 52.2 19.5 27.5 7.1 12.7 26.4 22.2 34.6 16.8 5.3 24.8 15.8 3.2 31.7 19.9 19.0 5.9 14.9 14.6 11.9 20.2 13.2 10.0 10.6 11.6 10.7 7.6 11.5 3.0 15.3 11.0 18.7 8.9 5.5 8.9 13.4 3.9 10.8 14.9 7.9 14.8 31.7 20.9 9.5 8.6 12.7 8.8 11.6 9.9 11.7 17.3 10.7 3.5 6.0 14.4 22.5 10.2 15.9 11.7 5.0 6.8 22.8 10.8 4.6 11.3 4.0 13.8 12.0 11.5 13.6 7.5 5.0 7.6 13.9 29.9 14.8 8.8 13.6 7.0 6.9 6.7 18.8 6.5 5.8 11.7 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 18.0 18.9 21.3 22.6 21.7 14.0 14.4 15.8 15.2 12.7 16.8 19.0 9.4 3.2 1.7 36.9 3.8 3.7 0.7 1.1 2.2 7.7 3.5 4.3 12.4 7.2 4.3 5.5 6.2 1.0 5.7 5.9 27.4 1.6 1.2 6.4 8.7 7.1 3.0 1.7 73.5 1.2 0.2 5.5 2.0 13.1 1.3 8.4 17.9 15.9 0.8 21.9 60.3 3.0 0.0 3.7 1.6 2.6 0.6 4.7 0.0 19.7 0.6 7.2 2.1 46.8 40.7 1.4 3.9 1.9 3.4 0.9 8.1 384.2 3.1 7.6 6.6 5.3 5.4 4.0 2.8 0.3 2.3 0.8 4.4 6.1 5.9 0.3 RAB11FIP5 "GAF1, KIAA0857, pp75, RIP11" ENSG00000135631 "RAB11 family interacting protein 5" Q9BXF6 2 73073382-73156721 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 44.7" "Cell type enhanced" "Detected in many" "Early spermatids: 86.2;Late spermatids: 171.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 38.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036406, HPA036407" Enhanced Enhanced "Vesicles,Centriolar satellite" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Vesicles, Centriolar satellite" "HPA036406: AB_2675105, HPA036407: AB_10669778" "unprognostic (1.49e-1)" "unprognostic (4.40e-3)" "unprognostic (1.41e-2)" "unprognostic (2.45e-3)" "unprognostic (1.67e-3)" "unprognostic (3.26e-2)" "unprognostic (1.58e-3)" "unprognostic (4.08e-3)" "unprognostic (2.27e-1)" "prognostic unfavorable (3.87e-4)" "unprognostic (3.23e-3)" "unprognostic (1.45e-1)" "prognostic favorable (2.26e-5)" "unprognostic (1.17e-2)" "unprognostic (1.61e-1)" "unprognostic (2.83e-1)" "unprognostic (9.66e-3)" 8.0 5.3 5.2 2.3 4.7 0.5 7.5 2.3 19.8 6.9 0.0 6.5 2.0 10.6 1.5 5.8 7.5 3.7 6.6 6.0 6.2 11.7 2.3 6.8 1.0 17.4 6.2 6.9 7.4 12.2 5.4 1.7 16.1 5.1 0.8 0.8 7.5 3.3 11.5 8.2 3.4 3.2 4.2 14.3 5.9 44.7 11.6 0.4 5.1 3.0 0.9 6.7 5.8 6.0 20.0 8.8 0.6 6.2 6.7 7.9 11.1 28.6 15.9 10.1 8.0 6.9 4.4 0.0 15.3 16.3 10.7 8.1 4.1 8.6 4.4 38.1 11.1 7.8 4.0 4.2 7.8 0.0 1.4 9.5 8.9 12.5 8.3 9.3 13.5 3.6 6.0 3.6 7.1 0.6 0.1 0.2 4.8 3.2 15.0 7.1 7.8 18.3 8.7 2.7 2.8 2.9 10.0 3.3 4.3 2.1 2.2 0.5 35.4 24.4 13.2 17.3 15.0 13.8 4.3 0.1 18.0 8.5 2.5 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 5.2 4.7 2.3 19.8 6.0 6.2 17.4 6.2 16.1 4.2 11.6 6.0 12.1 6.4 3.6 4.6 1.3 25.5 8.3 6.7 12.5 4.4 13.0 6.9 12.0 12.8 3.7 20.2 0.0 1.2 5.5 7.7 27.4 12.1 86.2 6.1 3.2 20.4 1.8 0.0 11.1 18.4 12.2 9.0 3.1 12.8 0.0 34.5 16.8 6.1 2.1 6.7 11.5 2.5 2.0 1.3 8.1 171.6 14.3 1.9 8.8 7.5 1.0 7.4 1.0 1.0 1.3 22.7 2.7 8.6 6.1 13.4 0.4 46.9 5.0 2.6 26.3 7.2 6.2 39.8 6.6 5.1 17.6 14.8 4.5 6.4 4.6 16.4 RAB12 ENSG00000206418 "RAB12, member RAS oncogene family" Q6IQ22 18 8609437-8639382 "Predicted intracellular proteins" "Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 193.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 96.4;Inhibitory neurons: 46.3;Microglial cells: 45.9;Oligodendrocytes: 43.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040727 Approved Approved Vesicles NA NA "Cluster 42: Non-specific - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Vesicles "HPA040727: AB_10794858" "unprognostic (7.92e-2)" "unprognostic (4.11e-2)" "unprognostic (1.05e-1)" "unprognostic (1.72e-2)" "unprognostic (1.53e-2)" "unprognostic (1.47e-2)" "unprognostic (1.25e-2)" "unprognostic (2.77e-2)" "unprognostic (1.11e-1)" "unprognostic (1.29e-3)" "unprognostic (2.67e-1)" "unprognostic (5.72e-2)" "unprognostic (2.02e-1)" "unprognostic (1.63e-1)" "unprognostic (1.46e-1)" "unprognostic (1.61e-1)" "unprognostic (9.11e-2)" 36.8 26.2 27.0 17.8 29.8 13.6 27.9 31.6 33.9 28.3 21.6 34.9 11.8 29.7 19.6 28.8 26.7 18.5 85.4 30.0 31.3 31.4 36.5 30.3 20.9 25.3 27.3 31.0 13.4 21.7 21.3 30.0 25.8 22.7 16.9 22.6 18.0 29.7 193.8 31.5 20.2 34.3 28.3 28.0 19.2 12.0 32.7 15.2 19.8 106.6 20.8 29.0 25.3 27.2 33.1 19.4 22.1 23.2 64.3 54.2 12.2 44.0 60.2 49.1 57.4 26.3 29.7 11.3 41.7 53.1 36.8 20.6 25.7 47.1 59.3 4.5 20.8 9.7 20.7 27.7 59.5 12.8 9.8 53.9 65.2 36.3 45.9 50.6 60.2 10.0 15.0 15.8 48.2 35.9 14.8 12.9 14.3 113.8 18.0 10.2 53.6 10.9 48.5 43.8 36.5 25.8 33.6 45.1 57.6 31.0 13.2 19.5 50.6 56.6 33.0 57.2 67.7 10.6 6.6 9.8 42.4 11.8 37.0 4.5 0.9 1.0 0.8 1.5 1.1 1.3 0.9 0.9 0.7 1.1 1.1 1.1 1.6 1.5 2.4 1.7 1.0 0.5 27.0 29.8 31.6 33.9 30.0 31.3 25.3 27.3 25.8 28.3 32.7 27.2 34.1 12.8 19.3 31.6 3.8 6.5 1.7 1.9 2.8 15.1 11.6 12.2 96.4 1.5 8.3 3.7 6.2 1.8 7.1 1.6 3.9 2.3 0.0 8.1 14.1 16.1 5.4 3.2 41.6 1.3 1.4 14.5 4.6 7.6 6.3 9.4 16.4 16.0 1.7 11.8 46.3 2.5 2.0 16.6 12.3 0.4 3.4 9.3 3.6 45.9 4.5 14.1 2.1 23.6 43.3 3.2 1.7 4.5 2.4 6.3 2.2 5.9 7.0 7.7 0.0 13.2 13.6 1.0 1.5 4.5 8.4 1.1 4.5 12.3 3.1 4.5 RAB14 "FBP, RAB-14" ENSG00000119396 "RAB14, member RAS oncogene family" P61106 9 121178133-121223014 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026419, CAB037066" Approved Supported Vesicles NA NA 2700000 "Cluster 14: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB037066: AB_1841128, HPA026419: AB_1855996" "unprognostic (1.30e-3)" "unprognostic (3.12e-2)" "unprognostic (9.01e-2)" "unprognostic (7.18e-2)" "unprognostic (6.53e-2)" "unprognostic (3.00e-1)" "unprognostic (1.39e-1)" "unprognostic (1.18e-1)" "unprognostic (2.52e-1)" "unprognostic (6.90e-2)" "unprognostic (3.05e-2)" "unprognostic (9.71e-3)" "prognostic favorable (1.79e-8)" "unprognostic (1.38e-1)" "unprognostic (3.17e-2)" "unprognostic (2.13e-1)" "unprognostic (1.09e-1)" 39.0 38.7 37.5 35.6 39.7 66.5 42.1 40.3 47.7 37.8 32.6 42.8 39.9 35.6 34.2 63.2 34.0 30.7 32.4 38.4 40.9 50.0 82.8 49.2 41.1 39.6 39.9 35.9 27.6 45.8 28.9 43.1 40.5 38.8 42.4 45.5 34.6 38.1 39.4 56.4 38.9 33.4 40.8 38.3 44.3 33.8 40.2 35.2 43.8 38.9 49.5 43.9 40.8 46.8 53.8 53.7 66.9 56.3 76.2 82.5 52.6 74.8 59.6 56.6 44.7 42.6 57.0 51.2 42.5 72.0 49.2 100.1 48.1 55.8 63.6 44.4 31.7 55.7 69.0 43.9 52.6 60.1 63.8 53.0 98.5 58.2 63.4 62.5 81.2 47.1 42.8 45.6 85.6 50.8 58.5 48.1 39.7 104.8 59.9 45.8 72.3 60.4 62.3 76.0 58.9 34.4 89.0 78.0 53.8 47.1 82.1 46.8 76.0 60.1 43.9 75.3 53.0 40.8 82.6 52.3 56.6 51.9 80.7 34.4 29.4 33.5 22.4 41.5 22.4 24.6 20.9 24.7 31.4 23.4 24.6 25.0 31.8 26.5 43.7 19.0 29.3 24.0 37.5 39.7 40.3 47.7 38.4 40.9 39.6 39.9 40.5 40.8 40.2 46.8 102.6 160.3 103.9 23.5 64.4 157.9 78.2 84.8 97.3 93.8 70.7 58.8 39.2 62.9 96.2 62.5 37.5 85.2 79.6 95.1 86.1 81.3 41.9 80.7 89.8 84.5 60.3 44.4 42.5 64.4 83.0 68.7 64.7 94.4 77.2 58.1 61.1 113.6 91.0 94.2 38.0 59.8 95.6 89.9 105.4 36.2 51.9 80.7 110.3 44.0 84.8 100.5 49.4 38.2 59.0 80.7 52.9 56.4 50.2 81.0 63.2 103.3 86.8 62.0 59.2 64.0 105.6 112.9 113.6 120.0 202.4 116.2 74.3 82.5 64.0 106.0 RAB15 ENSG00000139998 "RAB15, member RAS oncogene family" P59190 14 64945814-64973226 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 51.3;Inhibitory neurons: 28.0;Intestinal goblet cells: 35.2" "Cancer enhanced" "Detected in all" "testis cancer: 83.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 1.9" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.9" "Cell line enhanced" "Detected in many" "HAP1: 128.1;RH-30: 151.2;RT4: 116.1;SK-BR-3: 116.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041177 Uncertain Approved "Vesicles,Centriolar satellite" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Centriolar satellite" "HPA041177: AB_10794547" "unprognostic (9.80e-2)" "unprognostic (1.42e-2)" "unprognostic (1.53e-1)" "unprognostic (4.94e-2)" "unprognostic (6.29e-2)" "unprognostic (3.45e-1)" "prognostic unfavorable (4.68e-4)" "unprognostic (7.14e-2)" "unprognostic (3.12e-1)" "unprognostic (4.25e-2)" "unprognostic (2.79e-2)" "unprognostic (2.02e-1)" "unprognostic (1.98e-2)" "unprognostic (1.29e-2)" "unprognostic (1.63e-1)" "unprognostic (1.86e-2)" "unprognostic (2.82e-2)" 2.8 4.9 30.0 6.2 35.0 0.8 8.4 28.2 43.2 7.3 13.4 13.5 12.7 4.2 5.6 4.3 4.7 6.2 33.4 38.9 22.6 19.3 21.2 9.9 3.8 21.2 20.7 2.2 12.6 39.4 9.6 16.1 28.6 10.9 20.2 5.8 36.5 4.6 10.0 7.2 13.1 11.8 17.2 2.8 10.9 1.7 25.5 7.7 6.7 1.2 3.0 17.9 5.0 31.5 10.9 57.0 20.3 20.3 4.5 6.4 57.6 6.7 9.3 13.5 11.8 26.8 28.4 0.6 3.9 16.5 6.2 10.9 128.1 1.3 9.5 3.6 6.2 12.3 1.1 23.5 0.6 0.6 7.5 4.4 2.5 5.9 1.2 3.5 42.6 29.2 0.4 2.0 23.9 61.8 15.2 11.3 45.8 65.6 8.2 18.5 151.2 1.0 15.8 116.1 65.4 12.7 3.4 116.7 15.0 23.6 33.2 11.8 11.2 11.5 49.0 5.5 8.7 0.6 0.4 5.8 2.4 0.3 8.6 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 1.9 0.1 0.0 30.0 35.0 28.2 43.2 38.9 22.6 21.2 20.7 28.6 17.2 25.5 31.5 1.7 6.4 3.9 5.9 0.8 2.5 3.2 1.3 0.6 2.9 12.4 7.4 22.2 4.3 4.2 16.5 0.0 24.7 5.0 5.5 3.9 7.9 0.5 6.6 2.8 3.7 1.2 0.0 51.3 12.2 16.0 2.0 2.6 13.6 1.3 4.1 4.6 8.7 2.7 11.8 28.0 35.2 0.0 0.3 1.3 1.1 0.3 0.9 0.0 4.7 1.0 2.0 1.0 10.6 4.9 13.0 5.5 1.5 0.2 5.6 2.9 5.9 1.3 2.9 0.0 2.4 5.2 0.9 0.4 1.6 1.1 17.9 1.5 1.5 12.0 14.1 RAB20 FLJ20429 ENSG00000139832 "RAB20, member RAS oncogene family" Q9NX57 13 110523066-110561722 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 91.3;Hofbauer cells: 105.0;Kupffer cells: 92.1;Macrophages: 100.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "OE19: 60.9;SK-BR-3: 85.7;T-47d: 54.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA002882, HPA052111, HPA068647" Uncertain Supported "Golgi apparatus,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Vesicles" "HPA002882: , HPA052111: AB_2681732, HPA068647: AB_2686013" "unprognostic (5.59e-3)" "unprognostic (1.30e-1)" "unprognostic (3.48e-1)" "unprognostic (1.42e-3)" "unprognostic (1.30e-1)" "unprognostic (3.82e-2)" "unprognostic (1.14e-2)" "unprognostic (5.99e-2)" "unprognostic (9.43e-2)" "unprognostic (2.06e-2)" "unprognostic (9.41e-2)" "unprognostic (2.65e-1)" "prognostic favorable (8.57e-4)" "unprognostic (6.96e-2)" "unprognostic (4.32e-2)" "unprognostic (2.28e-2)" "prognostic favorable (4.48e-4)" 31.1 55.4 5.7 21.7 5.5 25.3 23.4 5.6 7.9 11.7 9.6 20.7 27.6 6.9 4.8 4.6 11.5 18.0 21.4 5.2 7.0 26.1 51.4 30.7 16.4 7.0 6.0 20.5 24.2 6.2 9.7 22.8 6.8 12.1 14.3 2.6 10.7 5.0 5.8 4.6 25.3 7.6 6.6 44.5 28.6 10.6 7.4 3.9 22.0 2.3 5.1 20.6 6.7 8.4 20.1 2.9 1.9 3.8 12.4 3.3 31.3 1.7 6.2 8.1 12.5 47.9 39.9 0.0 13.9 1.7 10.8 7.5 3.8 12.3 4.2 22.5 3.0 19.8 3.6 22.6 7.8 2.8 5.7 6.9 2.0 4.2 1.2 6.3 3.1 3.3 3.8 0.0 1.8 24.0 0.1 29.0 4.0 60.9 8.5 1.9 0.1 9.0 14.2 26.3 0.5 2.1 3.8 85.7 27.4 6.2 54.4 30.5 2.3 2.0 4.2 0.2 2.7 0.1 0.0 0.2 27.7 38.9 4.2 7.8 35.5 7.1 1.0 33.3 1.3 3.5 2.8 0.9 15.8 2.8 6.5 2.3 26.3 0.0 26.6 0.8 0.9 11.2 5.7 5.5 5.6 7.9 5.2 7.0 7.0 6.0 6.8 6.6 7.4 8.4 18.6 19.2 20.4 4.2 10.6 4.5 10.9 14.1 10.8 0.2 12.8 13.0 5.0 48.6 16.2 25.8 0.0 34.6 1.8 31.1 31.3 60.3 1.6 20.7 2.6 10.3 18.0 0.0 0.4 67.9 91.3 11.5 15.3 23.2 21.0 41.1 53.6 34.5 105.0 0.0 0.4 23.9 28.5 92.1 19.9 1.6 3.7 100.5 7.2 8.4 16.2 7.4 0.0 4.5 0.1 36.4 17.2 6.4 0.4 8.0 48.1 68.9 20.4 2.0 13.1 6.2 26.2 1.0 13.2 1.9 3.0 20.0 3.6 7.2 24.0 11.1 RAB26 ENSG00000167964 "RAB26, member RAS oncogene family" Q9ULW5 16 2140803-2154165 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.9;choroid plexus: 43.0;liver: 45.9;pancreas: 42.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 36.1;Enteroendocrine cells: 99.4;Excitatory neurons: 52.0;Inhibitory neurons: 28.3;Intestinal goblet cells: 41.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 20.1;HeLa: 23.2;MCF7: 13.5;SCLC-21H: 27.2;SK-BR-3: 24.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075624 Uncertain "Vesicles,Plasma membrane,Centrosome" "Intracellular and membrane" No No "Cluster 22: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Vesicles, Plasma membrane" Centrosome "HPA075624: " "unprognostic (1.01e-2)" "prognostic favorable (8.20e-5)" "unprognostic (7.25e-2)" "unprognostic (1.52e-1)" "unprognostic (7.34e-2)" "unprognostic (9.41e-3)" "unprognostic (2.81e-2)" "unprognostic (5.10e-2)" "unprognostic (1.82e-2)" "unprognostic (3.55e-2)" "unprognostic (3.75e-2)" "unprognostic (2.14e-1)" "unprognostic (6.48e-2)" "unprognostic (5.68e-2)" "unprognostic (1.23e-1)" "unprognostic (7.16e-2)" "unprognostic (2.92e-3)" 0.3 1.1 53.5 0.1 55.8 0.2 0.9 57.7 84.9 1.7 43.0 5.7 5.6 0.2 1.8 1.6 0.6 0.8 1.8 60.7 46.2 1.4 45.9 0.3 0.3 48.0 45.4 0.2 42.7 3.4 34.0 0.0 49.1 4.9 5.1 6.8 18.4 0.8 1.1 1.5 6.4 0.1 44.0 0.7 13.7 1.0 47.6 0.3 1.7 2.1 0.8 0.8 0.7 51.9 1.7 20.1 0.1 5.1 0.3 0.1 0.1 0.9 1.6 0.7 1.3 0.6 4.0 0.3 1.4 1.3 0.6 3.2 1.1 0.4 0.1 2.2 2.1 0.8 23.2 1.8 0.8 0.0 0.6 0.8 0.2 0.2 0.3 4.6 0.4 3.2 0.4 0.0 2.3 13.5 0.1 1.0 1.2 6.5 1.8 1.7 1.6 3.5 7.7 1.4 27.2 5.4 0.6 24.9 1.0 0.3 8.2 0.3 0.9 0.0 3.5 0.4 0.4 2.9 0.1 0.3 0.5 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 53.5 55.8 57.7 84.9 60.7 46.2 48.0 45.4 49.1 44.0 47.6 51.9 0.2 0.0 1.1 6.5 1.3 1.3 1.6 1.4 8.0 36.1 1.4 1.4 1.6 1.5 3.4 0.0 4.2 0.0 0.0 2.6 0.0 0.4 0.1 1.0 0.3 0.4 99.4 0.0 52.0 1.0 0.0 0.4 12.8 0.4 0.0 0.5 1.1 8.1 0.2 1.7 28.3 41.9 4.1 0.3 0.0 0.1 0.0 0.1 3.6 8.4 0.0 10.7 0.0 20.1 3.6 0.5 1.8 0.0 3.8 1.5 10.5 0.6 2.3 9.1 0.0 0.3 0.3 0.0 2.4 1.5 0.1 0.1 0.2 0.3 3.2 2.6 RAB29 "RAB7L, RAB7L1" ENSG00000117280 "RAB29, member RAS oncogene family" O14966 1 205767986-205775482 "Predicted intracellular proteins" "Differentiation, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 73.1" "Cell type enhanced" "Detected in many" "dendritic cells: 82.3;monocytes: 76.4;NK-cells: 129.8;Proximal tubular cells: 187.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020822, HPA026303" Approved Supported Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "CAB020822: , HPA026303: AB_1856016" "unprognostic (5.38e-2)" "unprognostic (1.76e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (1.82e-5)" "unprognostic (9.50e-2)" "unprognostic (1.56e-1)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.60e-2)" "unprognostic (3.14e-1)" "unprognostic (5.50e-2)" "unprognostic (2.45e-1)" "unprognostic (3.05e-2)" "unprognostic (1.06e-2)" "unprognostic (2.16e-1)" "unprognostic (1.53e-1)" "unprognostic (8.20e-3)" "unprognostic (1.42e-1)" 13.5 14.4 12.5 20.4 14.1 7.1 14.1 14.3 12.1 8.7 10.5 12.6 10.6 8.3 23.8 7.8 6.2 16.9 13.1 12.3 14.3 73.1 19.4 13.5 35.1 15.9 12.9 7.9 9.2 25.5 5.9 7.2 15.8 13.8 10.1 6.8 19.8 13.9 6.4 5.5 12.4 14.8 14.3 24.3 10.4 4.6 15.3 12.1 33.4 6.0 28.0 15.7 5.7 17.0 20.4 18.6 2.8 13.1 52.5 29.8 9.7 14.1 43.2 28.9 34.4 5.6 28.7 21.6 13.6 24.3 34.6 11.2 32.8 37.3 26.4 88.3 15.3 16.4 7.3 9.5 25.4 16.1 23.2 29.0 24.6 23.3 32.8 24.0 37.2 19.8 16.2 24.2 41.2 7.6 17.7 8.3 13.1 25.4 14.0 3.7 43.1 17.5 33.6 27.7 4.4 12.5 10.0 45.0 37.8 10.3 22.0 13.2 38.7 29.7 15.0 43.5 20.6 39.4 87.0 11.5 30.1 26.3 22.5 92.4 22.6 62.3 92.2 43.8 86.9 50.8 51.0 79.5 33.4 45.8 37.2 63.5 8.8 94.1 53.9 10.4 53.3 51.3 12.5 14.1 14.3 12.1 12.3 14.3 15.9 12.9 15.8 14.3 15.3 17.0 16.3 19.2 17.7 11.1 61.2 0.0 6.3 0.0 13.6 2.1 19.5 16.0 19.3 21.5 6.2 31.3 0.0 12.0 82.3 1.9 29.4 18.7 5.1 2.0 6.3 18.6 4.9 10.8 7.8 10.1 6.4 11.2 10.7 3.5 13.3 9.2 14.6 33.7 32.8 0.0 10.2 3.7 0.0 30.1 0.0 4.1 14.3 34.0 0.0 10.3 76.4 26.5 129.8 10.6 9.8 8.3 4.8 20.7 34.8 10.7 9.5 187.7 2.9 2.0 6.6 10.0 6.7 3.8 11.8 9.3 0.0 2.9 51.7 19.7 5.5 6.9 RAB30 ENSG00000137502 "RAB30, member RAS oncogene family" Q15771 11 82973133-83071923 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.7" "Cell type enhanced" "Detected in many" "Astrocytes: 87.8;Oligodendrocytes: 243.1;Plasma cells: 260.9" "Cancer enhanced" "Detected in all" "breast cancer: 6.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 54.4;naive B-cell: 55.0" "Lineage enriched" "Detected in many" 5 "B-cells: 55.0" "Cell line enhanced" "Detected in many" "Daudi: 55.7;HDLM-2: 57.6;U-698: 164.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054514, HPA060565" Approved Enhanced Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA054514: AB_2682512, HPA060565: AB_2684320" "unprognostic (3.21e-1)" "unprognostic (1.03e-1)" "unprognostic (1.82e-1)" "unprognostic (5.18e-2)" "unprognostic (7.21e-2)" "unprognostic (8.06e-2)" "unprognostic (2.91e-2)" "unprognostic (3.14e-2)" "unprognostic (4.36e-1)" "unprognostic (1.71e-2)" "unprognostic (1.53e-1)" "unprognostic (3.75e-2)" "unprognostic (1.64e-2)" "unprognostic (2.37e-1)" "unprognostic (2.42e-1)" "unprognostic (3.93e-2)" "unprognostic (1.85e-1)" 11.2 11.0 12.3 13.9 28.0 14.5 12.4 20.5 12.9 8.3 0.0 13.1 17.8 8.4 5.8 6.9 5.5 5.7 9.3 10.5 24.2 3.7 7.7 6.5 19.8 28.0 19.1 14.0 4.3 2.9 4.4 8.5 28.6 7.2 13.8 11.2 6.1 5.2 12.9 7.4 21.3 10.2 20.3 10.1 11.6 4.0 21.8 10.4 5.8 11.8 28.4 8.9 4.4 39.7 4.1 5.6 5.8 2.9 11.1 16.7 6.8 9.8 9.1 19.0 7.9 8.7 1.8 55.7 10.0 14.9 4.9 4.8 8.3 6.4 11.3 57.6 1.6 12.6 16.4 5.1 2.6 2.0 2.5 9.5 4.4 8.5 6.5 7.2 14.0 5.0 1.9 15.0 9.8 7.9 2.1 0.6 7.7 5.5 10.0 4.8 15.2 23.7 9.5 3.4 6.7 4.6 22.6 5.3 2.7 8.6 12.4 0.2 17.9 8.1 19.1 8.0 2.7 24.0 14.3 164.6 3.1 1.4 5.7 1.4 0.7 1.0 4.9 0.3 3.6 54.4 4.8 4.8 2.0 55.0 11.2 10.0 0.9 2.3 0.8 5.8 9.5 6.2 12.3 28.0 20.5 12.9 10.5 24.2 28.0 19.1 28.6 20.3 21.8 39.7 15.2 9.6 3.3 87.8 80.5 24.9 10.7 9.9 73.4 8.3 11.7 13.0 14.5 0.0 2.7 3.7 16.7 7.0 6.8 5.4 1.9 2.4 0.7 3.3 6.1 10.5 10.1 3.2 60.7 4.0 30.8 23.5 5.1 4.2 0.0 0.9 18.2 6.4 1.9 11.8 78.2 1.5 8.2 1.6 15.2 1.3 14.3 6.4 42.7 67.5 24.8 13.9 3.1 80.4 243.1 4.3 3.5 18.0 260.9 8.9 9.3 4.6 2.3 10.5 6.6 20.3 13.5 0.7 2.2 11.0 11.5 2.9 12.9 24.0 1.8 2.0 RAB33A RabS10 ENSG00000134594 "RAB33A, member RAS oncogene family" Q14088 X 130171962-130184870 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.5;choroid plexus: 16.4;heart muscle: 15.2" "Cell type enhanced" "Detected in many" "granulocytes: 22.9;Melanocytes: 12.4;NK-cells: 22.6;Oligodendrocytes: 23.5;T-cells: 12.9" "Group enriched" "Detected in many" 6 "glioma: 10.7;melanoma: 2.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 111.4;Karpas-707: 126.8;U-266/70: 88.5;U-937: 55.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059737 Uncertain Uncertain Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA059737: AB_2684115" "unprognostic (5.40e-2)" "unprognostic (6.64e-3)" "unprognostic (3.48e-2)" "unprognostic (8.47e-3)" "unprognostic (4.88e-2)" "unprognostic (1.17e-2)" "unprognostic (2.34e-1)" "unprognostic (1.76e-2)" "unprognostic (3.12e-2)" "unprognostic (4.16e-2)" "unprognostic (3.03e-2)" "unprognostic (8.28e-2)" "unprognostic (7.00e-6)" "unprognostic (2.51e-1)" "unprognostic (6.35e-2)" "unprognostic (3.45e-2)" "unprognostic (1.61e-1)" 2.3 1.3 23.6 4.0 28.2 6.3 1.3 27.9 31.6 2.3 16.4 0.9 0.7 1.7 0.5 0.5 1.6 2.6 15.2 24.4 24.4 1.7 0.9 1.7 11.6 29.0 24.7 1.4 0.2 2.0 2.2 1.4 29.7 0.4 1.0 7.6 0.5 0.1 0.1 1.1 2.2 0.7 27.8 2.5 1.4 0.6 25.7 4.8 0.6 0.2 12.3 1.7 0.8 41.5 0.3 0.2 7.5 0.0 3.2 1.0 0.1 1.0 2.2 1.9 3.2 0.1 0.8 5.8 0.1 0.6 0.5 0.2 9.4 0.2 2.0 30.2 0.1 35.0 0.1 0.0 31.3 28.4 111.4 1.0 0.2 0.6 1.3 1.0 0.8 34.7 0.1 126.8 0.3 0.3 13.1 9.7 1.1 0.1 1.3 0.0 0.0 1.6 0.2 0.0 24.3 19.4 0.2 0.3 0.5 0.4 0.0 15.2 0.2 0.1 0.1 0.4 0.2 88.5 29.7 0.0 3.9 55.1 0.0 39.9 1.3 87.4 32.0 0.8 20.0 20.2 29.0 32.5 10.0 8.8 27.8 40.0 4.1 19.5 5.4 1.0 72.8 18.1 23.6 28.2 27.9 31.6 24.4 24.4 29.0 24.7 29.7 27.8 25.7 41.5 1.7 0.0 1.1 1.6 3.2 1.9 0.6 0.5 1.2 10.9 0.3 1.0 8.4 2.8 0.2 0.0 2.1 0.9 8.9 0.0 0.0 0.0 1.2 0.4 0.8 2.0 0.0 6.6 4.0 0.2 1.3 4.5 0.0 0.8 22.9 2.9 2.5 0.1 1.9 5.0 3.2 0.4 2.0 0.3 12.0 1.2 1.8 6.3 12.4 1.9 2.5 1.6 22.6 4.5 23.5 0.8 0.0 0.4 3.3 0.4 0.0 0.2 0.3 9.3 0.0 0.0 2.2 0.1 1.2 0.2 1.1 1.4 12.9 0.2 0.3 0.6 RAB36 ENSG00000100228 "RAB36, member RAS oncogene family" O95755 22 23145326-23164350 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 32.8" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 41.2;Late spermatids: 24.5;Respiratory ciliated cells: 69.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 11.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 11.0" "Cell line enhanced" "Detected in many" "RPMI-8226: 25.5;U-266/84: 26.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059631 Approved Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 25: RPMI-8226 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA059631: " "unprognostic (2.74e-2)" "unprognostic (1.32e-3)" "unprognostic (2.06e-2)" "unprognostic (1.23e-2)" "unprognostic (1.15e-2)" "unprognostic (6.60e-2)" "unprognostic (1.22e-1)" "unprognostic (3.46e-1)" "unprognostic (2.49e-2)" "unprognostic (7.94e-2)" "unprognostic (2.02e-3)" "unprognostic (5.56e-3)" "prognostic favorable (4.55e-4)" "unprognostic (7.08e-2)" "unprognostic (7.18e-2)" "unprognostic (1.64e-1)" "unprognostic (3.08e-1)" 2.0 5.1 8.8 1.3 8.7 0.7 2.6 3.8 8.4 5.1 21.7 3.2 0.7 4.8 4.4 2.1 32.8 5.3 1.4 9.9 9.1 9.1 0.4 4.8 1.1 9.4 11.2 6.2 3.4 5.6 17.1 2.9 6.9 3.9 1.1 2.0 3.3 6.6 0.6 1.8 1.2 3.8 7.9 1.6 2.1 6.7 10.4 0.3 17.6 0.4 1.3 2.5 2.1 5.1 8.1 9.4 7.1 10.7 1.6 3.4 2.8 4.5 9.1 9.8 3.7 0.6 0.0 0.0 4.8 6.0 5.4 10.0 0.3 5.2 3.1 0.0 4.3 0.1 0.4 0.9 4.1 0.0 1.2 4.3 1.9 9.1 1.8 6.4 1.4 0.0 0.4 8.1 0.4 6.4 0.1 0.1 0.9 5.3 2.5 0.0 0.0 25.5 12.7 1.5 17.3 7.5 0.4 3.9 2.2 0.5 0.0 0.9 0.8 1.3 2.9 3.4 6.5 17.3 26.2 0.1 8.8 0.0 5.8 0.3 0.6 0.0 0.5 0.2 0.3 0.8 0.1 0.2 0.2 0.2 0.3 0.3 11.0 1.6 0.3 0.0 0.0 0.3 8.8 8.7 3.8 8.4 9.9 9.1 9.4 11.2 6.9 7.9 10.4 5.1 0.6 0.0 3.2 3.6 1.4 0.5 0.8 4.2 0.0 0.7 1.8 2.8 0.8 4.3 7.0 1.8 6.2 6.0 0.3 0.0 5.9 3.5 10.6 41.2 2.9 0.7 6.7 0.0 2.9 0.2 0.4 2.0 1.5 2.6 1.3 2.4 1.1 0.1 0.4 1.7 1.7 0.7 6.1 0.8 0.3 24.5 3.4 0.3 1.8 1.0 0.5 3.6 1.0 1.5 1.0 0.2 0.2 3.0 0.3 0.4 0.0 9.6 69.6 0.7 0.0 1.0 2.0 3.6 1.6 0.5 0.1 2.9 0.4 4.5 0.3 0.4 RAB3D "D2-2, GOV, RAB16, RAD3D" ENSG00000105514 "RAB3D, member RAS oncogene family" O95716 19 11322068-11346270 "Plasma proteins, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 68.5;skin 1: 53.1" "Cell type enhanced" "Detected in many" "monocytes: 53.1;Squamous epithelial cells: 47.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 169.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 47.3;Karpas-707: 45.6;MCF7: 54.6;SK-BR-3: 68.8" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "spinal cord: 73.1" "CAB018067, HPA063283" Approved Approved Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "CAB018067: AB_606903, HPA063283: AB_2684976" "unprognostic (4.71e-3)" "unprognostic (3.00e-1)" "unprognostic (1.79e-1)" "unprognostic (3.99e-3)" "prognostic unfavorable (3.70e-4)" "unprognostic (4.17e-3)" "unprognostic (7.27e-3)" "unprognostic (1.55e-1)" "unprognostic (2.80e-1)" "unprognostic (8.76e-2)" "unprognostic (9.92e-2)" "unprognostic (4.45e-2)" "unprognostic (7.60e-2)" "unprognostic (2.22e-1)" "unprognostic (1.74e-1)" "unprognostic (9.15e-2)" "unprognostic (1.34e-1)" 5.5 3.4 11.5 5.1 9.9 17.6 12.2 8.5 13.0 15.0 6.3 8.1 8.1 7.3 6.1 34.1 8.7 3.9 3.6 16.1 13.0 5.8 1.8 8.7 2.4 20.7 10.8 4.2 68.5 4.4 4.7 7.2 23.4 17.1 8.6 1.7 30.1 8.1 2.5 53.1 6.1 8.8 12.2 8.8 19.5 1.4 15.2 4.7 6.2 4.2 9.1 7.0 15.2 14.1 1.5 14.2 4.4 17.7 7.1 12.3 0.9 1.3 3.8 2.5 2.5 5.1 0.5 0.6 16.0 8.6 4.7 19.1 7.5 11.9 2.2 7.8 1.1 5.8 6.7 5.8 4.4 3.1 13.2 5.3 47.3 2.1 5.1 6.5 20.5 4.3 2.1 45.6 0.8 54.6 2.2 6.9 3.7 28.7 14.4 2.1 0.0 16.1 22.0 14.2 4.9 9.5 4.3 68.8 9.3 6.0 41.1 35.1 7.9 2.4 0.8 11.4 0.2 15.5 21.3 3.2 8.4 19.0 2.6 123.5 84.1 95.6 3.2 51.4 5.6 2.2 3.2 2.6 35.5 2.2 2.2 2.7 169.1 1.6 41.3 0.9 5.7 26.3 11.5 9.9 8.5 13.0 16.1 13.0 20.7 10.8 23.4 12.2 15.2 14.1 10.0 6.4 17.2 4.6 4.0 15.7 4.5 13.7 12.5 0.7 23.6 14.1 4.3 10.0 19.1 14.7 0.0 8.0 4.4 5.7 11.7 4.8 0.5 5.4 6.6 9.7 18.6 5.9 9.2 25.6 6.6 5.4 23.0 14.0 12.7 4.1 17.9 1.5 9.4 0.0 5.4 29.3 4.1 40.0 2.4 0.2 4.4 16.0 8.8 5.6 53.1 5.3 2.1 1.0 1.3 12.7 5.8 4.9 8.5 11.7 1.4 3.6 1.8 0.4 6.6 3.3 8.5 0.1 2.5 47.8 37.8 10.4 3.9 3.8 15.4 5.9 RAB40A "Rar-2, RAR2A" ENSG00000172476 "RAB40A, member RAS oncogene family" Q8WXH6 X 103499130-103519489 "Cancer-related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "epididymis: 8.0" "Group enriched" "Detected in some" 5 "Astrocytes: 4.9;Excitatory neurons: 7.4;Inhibitory neurons: 7.3;Microglial cells: 5.6;Oligodendrocyte precursor cells: 6.6;Oligodendrocytes: 3.3;Peritubular cells: 6.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 3.3;NTERA-2: 3.7" HPA076172 Uncertain Vesicles NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA076172: " "unprognostic (3.49e-1)" "unprognostic (6.01e-2)" "unprognostic (4.33e-2)" "unprognostic (4.49e-3)" "unprognostic (8.73e-2)" "unprognostic (1.08e-1)" "unprognostic (8.21e-2)" "unprognostic (1.72e-1)" "unprognostic (1.24e-1)" "unprognostic (4.05e-1)" "unprognostic (3.82e-2)" "unprognostic (4.43e-1)" "unprognostic (7.36e-4)" "unprognostic (7.85e-3)" "unprognostic (9.39e-5)" "unprognostic (1.43e-1)" "unprognostic (1.11e-3)" 2.0 1.2 1.0 0.2 3.1 0.1 0.9 0.7 1.4 3.0 6.4 0.6 0.4 4.5 8.0 7.1 2.3 0.5 0.7 1.6 1.2 1.3 0.3 1.3 0.2 0.8 0.3 4.6 0.5 0.2 2.4 0.6 0.3 3.5 0.3 1.3 0.4 2.1 0.2 0.5 0.5 0.9 0.0 0.6 0.8 3.8 1.1 0.1 0.7 0.2 0.1 2.3 1.5 1.0 0.2 0.9 3.3 0.1 0.7 0.9 1.6 1.0 0.2 0.1 0.3 0.7 0.5 0.8 1.2 0.2 1.0 0.0 0.2 0.0 0.1 0.0 2.0 0.2 1.8 0.2 0.3 0.0 0.1 0.7 0.1 0.3 0.2 1.2 0.2 0.3 1.2 0.5 0.3 0.2 0.2 0.1 3.7 0.0 0.5 0.0 0.2 0.0 0.0 0.3 1.4 1.7 0.3 0.0 0.7 0.9 0.0 0.1 1.7 1.3 0.8 2.1 0.9 0.6 0.4 0.6 1.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.1 0.7 1.4 1.6 1.2 0.8 0.3 0.3 0.0 1.1 1.0 0.3 0.0 0.0 4.9 0.0 0.0 0.7 0.1 0.0 0.2 0.1 0.4 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.6 0.1 0.0 0.0 7.4 0.0 0.2 0.2 0.0 0.1 0.0 1.0 0.0 0.0 0.1 0.0 7.3 0.1 0.0 0.0 0.0 0.7 0.9 0.0 0.0 5.6 0.0 0.2 0.0 6.6 3.3 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.2 0.0 0.1 0.0 0.1 0.3 0.0 0.3 0.0 0.0 RAB40AL "RAR2, RLGP" ENSG00000102128 "RAB40A like" P0C0E4 X 102937272-102938300 "Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.8;Cone photoreceptor cells: 2.1;Enteroendocrine cells: 3.0;Hepatic stellate cells: 2.2;Horizontal cells: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA076172 Uncertain Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 50: Fibroblasts - ECM organization" Vesicles "HPA076172: " "unprognostic (1.99e-1)" "unprognostic (3.05e-1)" "unprognostic (1.31e-1)" "unprognostic (1.11e-2)" "unprognostic (1.24e-1)" "unprognostic (1.04e-1)" "unprognostic (2.91e-1)" "unprognostic (1.39e-1)" "unprognostic (3.49e-1)" "unprognostic (1.83e-1)" "unprognostic (1.15e-1)" "unprognostic (2.18e-2)" "unprognostic (5.90e-10)" "unprognostic (4.74e-1)" "unprognostic (1.32e-1)" "unprognostic (5.02e-3)" "unprognostic (2.64e-2)" 0.1 0.1 0.5 0.0 0.4 0.0 0.1 0.2 1.1 0.1 0.3 0.1 0.1 0.2 0.3 0.1 0.1 0.0 0.1 0.5 0.4 0.1 0.2 0.1 0.0 0.3 0.0 0.2 0.1 0.0 0.2 0.0 0.3 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.8 0.1 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.4 0.2 1.1 0.5 0.4 0.3 0.0 0.3 0.0 0.1 0.8 0.2 0.0 0.0 0.0 0.4 0.1 0.1 0.0 1.2 1.8 0.1 0.1 0.1 0.0 0.0 0.0 2.1 0.9 1.3 0.6 0.0 0.0 0.1 0.1 0.2 0.4 3.0 0.4 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.1 2.2 0.9 0.4 1.7 0.0 0.2 0.0 0.8 0.0 1.0 1.5 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.3 1.5 0.0 0.5 0.4 0.0 0.0 0.6 0.0 1.2 0.1 0.3 0.3 0.1 0.0 0.7 0.0 0.1 0.6 0.3 RAB40B "RAR, SEC4L" ENSG00000141542 "RAB40B, member RAS oncogene family" Q12829 17 82654973-82698698 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 75.5" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 134.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 33.2;OE19: 40.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076172 Approved Vesicles NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" Vesicles "HPA076172: " "unprognostic (2.21e-2)" "unprognostic (7.50e-2)" "unprognostic (2.45e-1)" "unprognostic (1.34e-1)" "unprognostic (1.14e-1)" "unprognostic (6.03e-2)" "unprognostic (2.34e-2)" "prognostic favorable (9.77e-4)" "unprognostic (1.74e-1)" "unprognostic (3.28e-2)" "unprognostic (1.36e-1)" "unprognostic (3.14e-2)" "prognostic favorable (2.95e-6)" "unprognostic (1.81e-2)" "unprognostic (1.38e-1)" "unprognostic (2.13e-2)" "unprognostic (9.83e-3)" 8.5 8.6 53.6 2.0 63.1 0.8 9.8 52.1 60.5 8.7 25.7 13.2 7.4 8.7 14.7 9.2 7.6 5.3 19.0 52.1 44.4 19.4 14.7 5.2 2.0 58.0 55.1 12.4 6.7 5.0 15.9 3.1 52.7 9.4 7.8 3.4 9.7 5.4 42.5 13.0 6.2 4.1 51.6 4.2 17.5 5.1 53.2 2.1 6.2 19.7 2.3 11.3 9.3 75.5 7.3 11.7 3.5 10.5 8.6 10.7 5.2 7.9 2.2 4.9 1.6 3.8 1.9 1.0 15.4 8.0 3.1 13.1 6.8 6.4 4.3 0.6 33.2 2.8 12.2 10.9 4.3 0.8 3.1 9.2 10.2 2.8 2.2 4.7 4.6 7.0 8.5 1.0 6.7 9.7 2.8 6.4 0.7 40.6 15.3 6.8 9.1 6.3 17.2 13.3 19.1 12.1 5.6 5.0 11.1 16.0 10.8 5.9 9.4 13.7 4.1 14.5 6.5 5.5 4.7 10.5 3.2 1.9 2.4 1.4 0.5 0.0 0.9 1.2 1.3 2.7 1.2 1.6 0.8 0.8 1.6 0.8 0.1 2.0 3.3 6.5 1.8 0.7 53.6 63.1 52.1 60.5 52.1 44.4 58.0 55.1 52.7 51.6 53.2 75.5 19.0 9.6 8.8 22.5 5.8 30.0 28.4 21.4 19.9 11.4 30.0 37.1 32.8 44.3 13.4 14.7 0.0 2.5 9.9 40.0 82.2 22.1 37.3 25.2 17.8 14.6 21.0 6.1 39.2 8.7 5.6 22.2 61.7 59.9 1.3 4.9 15.4 21.3 6.8 33.7 17.6 48.0 73.2 3.2 11.0 26.6 20.2 5.8 48.0 9.4 2.7 11.7 11.3 21.1 134.8 10.3 42.4 18.4 18.6 55.5 43.7 86.7 12.2 11.3 26.3 17.4 17.0 5.0 11.4 30.0 29.1 1.2 6.5 18.5 44.7 99.0 RAB40C "RARL, RASL8C" ENSG00000197562 "RAB40C, member RAS oncogene family" Q96S21 16 589357-629272 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 58.0" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 14.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 14.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076172 Approved Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 50: Non-specific - Ribosome" "Cluster 43: THP-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA076172: " "unprognostic (8.04e-2)" "unprognostic (3.63e-1)" "unprognostic (2.00e-1)" "unprognostic (1.52e-1)" "unprognostic (5.38e-3)" "unprognostic (1.07e-2)" "prognostic unfavorable (1.18e-4)" "unprognostic (1.23e-1)" "unprognostic (4.61e-2)" "unprognostic (5.78e-2)" "unprognostic (3.45e-2)" "unprognostic (2.90e-1)" "unprognostic (1.37e-3)" "unprognostic (3.89e-2)" "unprognostic (6.20e-2)" "unprognostic (7.48e-2)" "unprognostic (4.00e-3)" 10.5 8.0 7.4 4.5 10.0 5.8 11.6 7.1 17.7 13.2 0.0 20.3 13.3 13.0 5.1 20.4 12.2 4.5 12.5 10.9 2.0 13.9 12.8 13.3 4.1 3.4 2.6 12.1 38.5 5.1 21.4 6.6 3.2 17.5 4.4 1.9 14.3 5.9 18.8 58.0 13.6 4.4 1.5 7.9 19.3 13.8 4.0 10.2 10.6 6.2 2.6 18.3 16.1 8.8 7.7 16.3 9.4 13.2 5.3 6.6 12.6 10.1 4.7 8.0 6.5 14.7 13.7 8.8 10.5 6.0 7.1 17.1 5.8 8.3 1.6 9.3 9.8 4.9 11.3 10.5 9.4 9.9 8.9 5.6 17.9 6.4 6.7 5.6 6.6 10.3 11.2 8.8 3.5 22.7 9.6 18.0 10.9 13.5 9.4 15.4 6.7 14.1 4.7 10.9 12.8 10.3 11.1 24.1 9.4 4.3 17.8 19.6 8.2 8.4 11.8 11.3 6.1 8.4 8.6 11.0 5.5 13.4 8.9 1.1 2.8 14.0 0.4 1.8 1.9 1.1 1.4 1.5 1.6 0.7 1.0 0.7 4.8 0.8 0.8 0.7 0.6 1.3 7.4 10.0 7.1 17.7 10.9 2.0 3.4 2.6 3.2 1.5 4.0 8.8 7.1 9.6 15.7 20.5 4.3 17.5 9.9 11.3 18.2 11.4 9.8 7.9 6.3 8.6 10.4 11.0 8.4 26.6 7.7 33.2 7.9 6.2 4.0 12.1 7.1 5.4 10.8 5.2 44.5 12.5 15.3 4.7 23.4 12.7 7.0 11.2 7.5 16.2 9.4 16.8 18.6 16.5 24.4 6.1 4.1 6.6 5.0 4.5 7.2 10.3 7.5 8.4 7.2 10.6 14.8 10.4 21.3 6.4 2.5 10.8 38.2 9.7 11.2 3.3 0.0 5.6 5.8 17.1 13.9 24.8 31.1 56.8 4.6 7.2 18.7 8.6 RAB41 ENSG00000147127 "RAB41, member RAS oncogene family" Q5JT25 X 70282093-70285002 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "retina: 65.5" "Cell type enriched" "Detected in some" 19 "Cone photoreceptor cells: 533.8" "Cancer enhanced" "Detected in some" "glioma: 2.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "U-2197: 3.7;U-87 MG: 4.6" "HPA001510, HPA065289" Uncertain Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Vesicles, Plasma membrane" "HPA001510: AB_1079733, HPA065289: " "unprognostic (1.32e-1)" "unprognostic (1.39e-1)" "unprognostic (3.36e-3)" "unprognostic (4.25e-3)" "unprognostic (1.18e-1)" "unprognostic (3.46e-2)" "unprognostic (6.33e-3)" "unprognostic (1.85e-3)" "unprognostic (1.38e-1)" "unprognostic (2.68e-2)" "unprognostic (2.20e-2)" "unprognostic (1.04e-3)" "unprognostic (7.63e-2)" "unprognostic (2.39e-1)" "unprognostic (9.78e-3)" "unprognostic (8.42e-2)" "unprognostic (9.89e-2)" 0.2 0.8 0.5 0.5 0.6 0.4 0.1 0.3 0.9 0.1 0.0 0.3 0.4 0.2 0.0 0.3 0.2 0.5 0.6 0.3 0.4 0.3 0.1 0.3 0.5 0.5 0.5 0.8 0.1 0.0 0.2 0.2 0.4 0.2 0.0 65.5 1.0 0.0 0.5 1.3 0.7 0.0 0.4 0.5 0.2 4.0 1.0 0.0 0.8 0.0 0.0 0.3 0.1 0.5 0.5 0.5 1.3 0.5 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.6 0.5 0.6 1.1 0.0 1.1 0.6 0.0 0.0 0.0 0.8 1.3 0.1 1.4 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 1.7 0.0 0.8 0.5 1.2 0.0 0.3 0.8 0.5 0.8 1.7 1.7 0.3 0.9 0.9 0.0 0.4 0.8 1.5 0.5 0.3 1.5 0.6 0.3 1.4 1.6 0.6 0.7 3.7 0.8 0.7 1.1 0.8 4.6 1.1 1.1 0.0 0.0 0.0 0.1 0.2 0.3 0.2 0.1 0.1 0.3 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.6 0.3 0.9 0.3 0.4 0.5 0.5 0.4 0.4 1.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 533.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 28.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RAB44 "dJ431A14.3, RASD3, RASL13" ENSG00000255587 "RAB44, member RAS oncogene family" Q7Z6P3 6 36697826-36733184 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 63 "bone marrow: 58.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 4.4;granulocytes: 14.5;monocytes: 2.3;Squamous epithelial cells: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "basophil: 10.6;eosinophil: 7.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 10.6" "Cell line enhanced" "Detected in some" "HEL: 21.9;HL-60: 30.9;HMC-1: 88.9;NB-4: 76.7;THP-1: 30.1;U-937: 60.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA079390 Approved Vesicles NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" Vesicles "HPA079390: " "unprognostic (8.86e-2)" "unprognostic (5.58e-3)" "unprognostic (5.09e-2)" "unprognostic (4.66e-2)" "unprognostic (1.37e-1)" "unprognostic (1.28e-3)" "unprognostic (9.56e-2)" "unprognostic (6.35e-4)" "unprognostic (1.45e-1)" "unprognostic (1.13e-1)" "unprognostic (7.13e-3)" "unprognostic (2.57e-1)" "unprognostic (3.02e-2)" "unprognostic (3.13e-3)" "unprognostic (3.03e-2)" "unprognostic (9.67e-3)" "unprognostic (5.79e-2)" 0.5 0.0 0.0 0.6 0.1 58.9 0.4 0.0 0.1 0.4 0.0 0.4 0.6 0.3 0.2 0.5 0.5 0.8 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.2 0.1 0.1 0.5 0.9 0.4 0.0 0.5 0.7 0.0 0.0 0.1 0.0 0.1 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 30.9 88.9 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 76.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 30.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.7 0.0 10.6 0.8 7.2 0.0 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.2 4.4 0.7 0.0 0.0 0.1 0.0 1.2 0.0 0.1 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.3 0.0 1.3 0.3 0.2 0.0 0.3 0.0 0.5 14.5 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 2.3 0.0 1.0 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.7 0.0 0.0 0.6 0.3 0.0 0.0 2.2 0.0 0.0 0.4 0.1 0.0 0.1 RAB5A RAB5 ENSG00000144566 "RAB5A, member RAS oncogene family" P20339 3 19947097-19985175 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Endocytosis, Phagocytosis, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004567, HPA049354" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Vesicles" "CAB004567: AB_628191, HPA049354: AB_2680725" "unprognostic (2.49e-3)" "unprognostic (1.95e-1)" "unprognostic (2.58e-2)" "unprognostic (4.72e-1)" "unprognostic (3.85e-1)" "unprognostic (5.58e-2)" "unprognostic (1.40e-2)" "unprognostic (6.75e-2)" "unprognostic (7.12e-2)" "unprognostic (5.97e-2)" "unprognostic (1.83e-3)" "unprognostic (4.68e-2)" "unprognostic (2.10e-2)" "unprognostic (1.93e-1)" "unprognostic (1.33e-1)" "unprognostic (2.45e-1)" "unprognostic (8.36e-2)" 35.7 27.3 39.2 27.0 39.9 41.4 33.2 42.1 49.5 30.5 36.6 29.7 29.6 22.7 42.4 42.3 21.1 32.2 36.3 38.6 43.1 33.6 42.8 29.5 24.3 42.7 42.5 19.9 27.2 53.8 20.5 49.2 42.2 30.7 30.5 35.4 35.8 28.8 29.1 36.0 28.2 28.0 44.0 24.2 32.6 18.0 41.1 28.9 41.1 30.3 29.1 35.4 29.7 46.1 29.8 26.8 38.5 26.4 65.8 57.8 38.9 51.3 59.7 47.8 55.0 31.9 45.7 21.8 30.3 56.7 27.6 18.4 29.0 38.2 55.7 37.9 24.1 31.9 24.9 31.1 82.2 45.0 38.1 53.6 71.0 56.1 81.9 59.9 61.6 28.5 37.1 34.1 57.9 46.2 34.8 31.9 48.4 40.8 42.6 25.8 27.2 32.2 98.9 38.8 12.0 39.6 36.9 45.3 60.3 57.0 35.4 35.8 61.6 34.5 30.1 44.4 44.2 42.0 73.5 28.6 55.0 40.4 57.1 28.7 18.0 31.3 7.9 19.6 10.6 7.9 9.3 9.6 18.1 5.8 8.5 8.1 36.0 20.3 26.3 11.8 10.9 11.5 39.2 39.9 42.1 49.5 38.6 43.1 42.7 42.5 42.2 44.0 41.1 46.1 114.8 60.9 45.1 33.0 43.6 170.0 129.5 48.8 62.0 34.0 57.0 35.9 57.0 27.1 52.6 42.3 31.3 74.7 44.2 68.7 103.7 52.2 21.2 45.9 44.4 72.4 62.0 55.3 33.7 45.3 67.2 65.2 66.3 72.0 85.0 39.1 41.7 39.3 54.2 15.2 31.4 59.4 65.1 44.4 158.8 15.9 36.7 60.9 83.6 28.1 43.1 86.1 41.2 65.9 44.1 65.2 55.9 35.3 50.7 109.7 49.4 62.3 48.1 36.8 52.6 86.5 72.4 24.6 27.1 65.0 188.0 164.3 60.6 37.1 41.5 151.0 RAB5B ENSG00000111540 "RAB5B, member RAS oncogene family" P61020 12 55973913-55996683 "Predicted intracellular proteins, RAS pathway related proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010224, HPA068337" Approved Supported Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "CAB010224: AB_2175453, HPA068337: AB_2685974" "prognostic unfavorable (2.24e-5)" "unprognostic (1.86e-1)" "unprognostic (1.91e-1)" "unprognostic (7.66e-3)" "unprognostic (2.09e-1)" "unprognostic (8.42e-2)" "unprognostic (9.16e-3)" "unprognostic (3.09e-1)" "unprognostic (3.13e-1)" "unprognostic (8.31e-3)" "unprognostic (8.64e-2)" "unprognostic (2.26e-1)" "unprognostic (2.27e-2)" "unprognostic (2.46e-2)" "unprognostic (2.74e-1)" "unprognostic (2.85e-1)" "unprognostic (2.49e-1)" 50.9 54.4 95.4 39.4 102.3 35.0 68.2 106.2 96.8 76.8 76.5 72.2 52.4 73.8 92.4 99.8 75.7 55.8 87.2 93.1 99.5 70.1 68.8 72.9 44.5 103.5 105.6 85.4 47.9 112.1 31.4 63.4 106.0 74.6 80.6 72.9 61.7 94.6 100.6 92.4 50.4 79.9 103.6 48.1 67.0 57.1 99.9 64.0 64.6 127.6 76.0 65.6 69.6 112.9 62.3 39.1 80.2 59.4 128.5 115.9 72.1 56.1 102.3 68.3 57.5 67.5 76.7 34.7 65.5 107.6 50.3 44.8 51.4 77.8 63.3 44.1 39.5 39.3 53.1 38.6 94.5 33.2 61.6 94.9 142.7 64.2 54.2 153.0 87.0 42.2 36.2 99.3 87.3 42.3 42.6 51.9 35.8 51.5 35.2 36.5 49.9 45.1 128.2 100.7 40.0 35.6 73.1 72.4 89.0 88.3 104.6 102.5 72.3 44.5 32.5 32.8 22.2 56.4 46.9 21.8 71.5 30.7 38.4 18.5 10.1 32.6 11.1 9.3 10.3 8.9 9.0 9.9 8.0 6.9 10.2 8.0 27.4 7.6 10.6 8.0 7.6 8.9 95.4 102.3 106.2 96.8 93.1 99.5 103.5 105.6 106.0 103.6 99.9 112.9 24.4 57.7 37.1 13.1 26.7 51.7 26.5 34.0 35.3 33.3 54.4 38.2 53.2 55.8 34.0 42.3 52.1 44.0 29.1 88.1 35.2 49.4 11.1 24.1 22.8 30.8 38.9 29.8 21.4 37.1 42.8 33.1 37.2 33.9 19.7 34.1 42.1 86.0 31.1 16.8 23.4 51.1 16.2 46.4 52.3 27.7 53.4 25.4 35.6 11.2 64.7 41.6 32.0 11.1 26.3 71.3 44.4 59.5 27.1 57.0 44.7 35.9 23.9 31.6 59.2 31.9 33.2 36.8 25.6 64.7 89.2 88.0 25.0 23.4 42.7 65.8 RABEP1 "neurocrescin, RAB5EP, rabaptin-5, RABPT5" ENSG00000029725 "Rabaptin, RAB GTPase binding effector protein 1" Q15276 17 5282265-5386340 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Endocytosis, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004549, HPA019669, HPA024235, HPA024691" Supported Supported Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB004549: AB_628192, HPA019669: AB_1856019, HPA024235: AB_1856020, HPA024691: AB_1856021" "unprognostic (3.22e-1)" "unprognostic (2.90e-2)" "unprognostic (2.45e-1)" "unprognostic (8.75e-3)" "unprognostic (1.64e-1)" "unprognostic (8.25e-2)" "unprognostic (3.71e-2)" "unprognostic (1.20e-1)" "unprognostic (1.60e-2)" "unprognostic (7.73e-2)" "prognostic favorable (6.43e-4)" "unprognostic (1.14e-1)" "unprognostic (6.09e-3)" "unprognostic (7.67e-2)" "unprognostic (2.60e-1)" "unprognostic (1.00e-1)" "unprognostic (9.00e-3)" 30.1 23.6 39.1 23.2 45.8 17.1 43.9 41.0 49.3 22.2 32.0 21.1 16.5 26.8 25.1 18.5 16.7 21.7 32.4 37.9 46.7 23.5 32.8 19.5 33.5 43.1 44.8 21.7 18.0 48.0 19.7 30.8 44.2 31.0 20.7 58.2 22.7 21.8 68.5 16.3 18.9 27.5 43.5 28.3 24.0 18.8 43.7 37.3 25.8 52.4 40.3 23.1 15.2 50.7 45.5 57.5 59.6 33.3 60.9 60.5 31.2 58.3 44.5 61.8 58.5 51.4 19.7 98.3 46.0 61.2 35.0 35.9 87.8 50.0 86.4 60.7 75.0 60.9 73.1 39.4 56.4 41.3 37.9 47.2 33.3 59.6 76.5 37.7 54.4 49.9 52.3 48.3 54.2 32.7 66.1 30.4 26.8 25.8 24.9 61.2 70.8 32.4 30.6 43.1 25.3 39.4 52.4 52.8 49.5 52.3 95.9 17.2 46.9 53.1 24.2 52.6 69.6 26.9 31.0 52.4 41.2 62.3 37.5 14.9 21.1 22.4 25.0 22.7 21.9 80.4 19.5 24.0 22.6 96.7 24.6 21.5 30.4 22.6 50.9 35.0 20.0 16.6 39.1 45.8 41.0 49.3 37.9 46.7 43.1 44.8 44.2 43.5 43.7 50.7 36.4 35.3 45.1 57.5 53.8 24.0 30.1 17.0 25.6 51.5 87.3 46.0 91.1 14.3 32.9 18.4 39.6 39.7 47.2 18.6 41.1 30.4 7.6 19.8 55.5 37.9 16.3 58.3 123.7 23.8 35.0 38.5 23.4 25.3 12.6 47.0 34.2 31.7 89.8 35.3 115.9 17.1 30.5 32.1 38.2 6.0 33.8 36.5 30.2 90.9 32.8 89.7 63.8 78.4 114.1 28.3 65.5 28.2 28.2 52.8 16.5 38.1 19.0 52.5 26.3 34.3 47.7 82.2 75.7 25.5 20.3 25.9 34.4 61.2 18.9 33.6 RABEP2 "FLJ23282, FRA" ENSG00000177548 "Rabaptin, RAB GTPase binding effector protein 2" Q9H5N1 16 28904421-28936526 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047641 Approved Supported Vesicles,Cytosol NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 64: Macrophages - Immune response" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 57: B-cells - Immune response" "Vesicles, Cytosol" "HPA047641: AB_2680111" "unprognostic (4.93e-2)" "unprognostic (1.21e-2)" "unprognostic (2.13e-2)" "unprognostic (7.06e-2)" "unprognostic (1.44e-1)" "prognostic favorable (5.84e-4)" "unprognostic (2.46e-1)" "unprognostic (1.42e-1)" "unprognostic (8.41e-2)" "unprognostic (6.13e-2)" "unprognostic (1.26e-3)" "unprognostic (5.86e-2)" "prognostic favorable (1.24e-6)" "unprognostic (7.50e-2)" "unprognostic (8.20e-2)" "unprognostic (1.08e-1)" "unprognostic (5.92e-3)" 7.3 21.5 7.3 25.1 8.8 11.5 9.3 8.2 9.2 11.0 10.7 15.0 16.8 8.4 2.7 18.7 7.0 6.6 16.8 6.5 7.9 19.2 10.6 10.1 46.7 10.7 8.5 6.3 17.9 11.5 16.4 5.3 8.4 28.6 4.6 3.5 17.5 7.0 6.5 23.6 28.3 3.4 7.9 47.9 14.4 6.2 8.2 5.3 13.9 3.2 9.4 12.5 12.3 8.5 13.5 21.1 5.6 10.5 3.3 4.7 10.1 15.5 9.2 10.9 10.7 15.9 12.0 27.7 23.7 6.5 4.4 17.8 2.2 9.9 2.1 9.5 9.9 10.5 17.0 21.7 6.5 7.7 32.1 7.9 8.0 13.5 2.4 6.3 15.5 7.4 4.9 9.7 8.5 31.9 9.5 17.8 7.3 5.4 11.4 33.6 5.1 17.4 7.5 17.5 8.6 11.1 7.6 34.8 7.0 1.2 27.6 15.9 27.5 16.4 8.4 12.1 15.6 15.3 5.0 20.7 17.3 18.2 12.6 0.9 2.8 2.4 3.5 2.9 2.4 12.1 2.5 3.2 3.7 15.0 2.2 2.1 0.7 5.5 3.3 2.2 2.2 2.8 7.3 8.8 8.2 9.2 6.5 7.9 10.7 8.5 8.4 7.9 8.2 8.5 11.5 3.2 10.0 4.9 42.4 5.1 14.7 14.6 17.6 11.1 13.3 11.0 1.9 11.5 12.9 20.2 35.5 26.1 21.0 35.0 17.6 16.0 0.7 9.2 8.2 14.2 17.3 6.5 4.8 20.9 7.1 9.0 23.0 10.0 18.4 12.1 7.9 4.2 12.4 15.2 6.5 33.7 18.3 8.4 11.3 1.3 4.1 10.5 10.6 9.4 11.6 8.6 22.6 5.0 8.4 20.0 44.1 6.4 21.4 15.4 32.3 11.6 8.0 43.4 13.1 7.9 9.6 4.3 6.0 16.6 8.4 22.0 14.5 22.6 26.7 19.0 RABGGTB ENSG00000137955 "Rab geranylgeranyltransferase subunit beta" P53611 1 75786197-75795086 "Enzymes, Predicted intracellular proteins" "Prenyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026585, HPA027167, HPA030793" Approved Supported Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA026585: AB_1856026, HPA027167: AB_1856027, HPA030793: " "unprognostic (4.83e-2)" "unprognostic (3.04e-1)" "unprognostic (2.09e-2)" "unprognostic (2.45e-2)" "unprognostic (9.02e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (9.80e-5)" "unprognostic (9.62e-3)" "unprognostic (2.93e-1)" "unprognostic (1.93e-1)" "unprognostic (2.23e-1)" "unprognostic (6.95e-2)" "prognostic unfavorable (1.12e-5)" "unprognostic (6.05e-2)" "unprognostic (1.56e-1)" "unprognostic (6.77e-2)" "unprognostic (3.89e-1)" 37.5 56.5 41.0 20.3 44.9 18.3 41.4 44.7 52.8 31.4 40.4 33.9 33.3 24.6 23.6 35.2 28.1 21.4 49.6 40.0 44.8 75.9 67.2 29.0 26.9 44.8 43.6 38.1 67.7 37.5 25.1 31.5 44.8 27.5 29.3 41.2 32.0 23.0 79.7 21.7 24.9 23.0 47.1 29.1 33.9 15.3 43.6 30.6 30.5 84.0 31.3 37.3 30.4 47.9 74.8 40.2 68.6 31.4 85.2 108.8 43.8 99.5 68.2 91.6 70.4 97.3 17.6 68.2 101.3 55.7 146.0 46.0 178.3 77.7 133.8 67.1 48.3 58.0 66.5 158.0 106.6 74.8 32.9 67.5 165.1 84.3 95.4 125.6 75.8 59.7 96.9 65.7 109.9 30.8 61.5 81.4 64.5 53.3 78.0 49.2 114.5 29.9 69.9 41.7 43.5 39.1 24.1 123.6 231.0 58.8 26.1 69.8 77.5 59.6 67.0 142.1 199.5 41.9 127.1 46.4 67.5 60.3 27.0 8.4 7.2 4.7 7.7 11.3 9.3 9.5 7.7 7.2 12.3 5.9 9.4 9.3 1.1 6.3 8.1 11.3 7.7 4.0 41.0 44.9 44.7 52.8 40.0 44.8 44.8 43.6 44.8 47.1 43.6 47.9 35.3 35.3 44.3 12.7 83.3 127.7 59.4 132.6 66.0 22.6 58.5 45.6 71.1 72.9 86.0 27.6 20.9 45.9 65.7 38.6 103.7 44.9 1.6 36.1 42.5 45.8 89.8 41.6 17.1 51.8 60.3 48.6 57.6 40.4 70.5 26.5 41.7 68.6 61.2 32.0 17.8 62.2 75.3 61.3 91.4 4.4 32.3 54.8 58.7 9.4 52.0 36.5 32.0 14.6 21.9 44.1 46.0 33.4 78.8 84.8 58.4 206.5 45.8 22.3 6.6 40.1 59.8 20.1 14.0 73.6 142.9 53.5 60.2 37.5 69.6 88.7 RABL2A ENSG00000144134 "RAB, member of RAS oncogene family like 2A" Q9UBK7 2 113627229-113643396 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 19.8" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 123.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MOLT-4: 10.6" "HPA042642, HPA042700, HPA044007" Approved Approved Vesicles,Centrosome NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" Centrosome Vesicles "HPA042642: , HPA042700: AB_2678120, HPA044007: AB_2678770" "unprognostic (7.76e-3)" "unprognostic (7.79e-3)" "unprognostic (7.00e-2)" "unprognostic (2.94e-2)" "unprognostic (1.99e-1)" "unprognostic (4.23e-2)" "unprognostic (4.89e-2)" "unprognostic (6.77e-3)" "unprognostic (6.61e-2)" "unprognostic (7.36e-2)" "unprognostic (5.78e-3)" "unprognostic (4.29e-2)" "prognostic unfavorable (1.20e-4)" "unprognostic (1.89e-2)" "unprognostic (1.50e-1)" "unprognostic (7.87e-2)" "unprognostic (3.19e-5)" 2.5 1.2 2.7 1.3 2.9 0.9 2.8 2.3 3.4 3.8 4.6 3.3 1.3 4.4 3.6 1.5 19.8 1.6 2.4 3.0 2.5 2.0 1.9 2.7 1.0 2.6 4.8 5.0 1.5 1.3 2.9 0.8 3.2 2.7 1.0 6.6 2.1 2.0 1.3 2.5 1.8 2.1 3.3 1.7 1.9 5.3 2.9 3.0 3.5 1.4 1.9 2.6 2.8 2.7 2.1 3.7 5.0 4.0 4.1 5.8 3.7 2.0 1.6 2.9 2.0 3.3 1.4 3.1 8.5 0.7 2.0 2.3 2.5 0.3 1.9 4.1 4.7 1.6 0.1 0.4 3.3 0.6 1.1 2.1 4.3 0.5 1.2 4.2 2.1 4.6 1.5 0.8 1.7 1.8 10.6 0.7 2.8 1.9 1.3 2.0 1.9 1.3 2.1 0.5 2.0 7.0 1.9 2.2 1.9 1.5 0.4 3.0 0.5 0.4 0.6 0.7 1.4 2.9 3.4 0.8 5.8 2.3 1.0 0.0 4.3 2.4 6.2 7.1 6.9 8.9 9.0 6.5 7.1 8.2 7.5 5.7 0.5 12.8 7.1 9.1 4.9 5.4 2.7 2.9 2.3 3.4 3.0 2.5 2.6 4.8 3.2 3.3 2.9 2.7 4.2 9.6 8.1 13.4 6.4 4.5 5.6 8.1 5.2 7.6 6.4 8.0 9.5 2.8 12.1 7.3 10.4 3.4 6.3 4.9 13.7 7.6 16.3 36.9 5.6 3.4 7.2 3.0 30.2 3.1 2.9 6.8 5.6 2.8 11.4 9.9 5.3 4.4 3.6 16.8 20.5 4.3 4.1 3.2 3.5 14.5 8.1 3.1 7.2 3.7 5.7 7.3 9.2 7.1 19.4 3.6 3.2 7.2 0.8 2.9 7.2 6.8 123.2 16.8 0.0 5.9 8.1 22.3 9.6 3.6 4.8 2.5 6.0 4.4 4.1 3.6 RABL2B ENSG00000079974 "RAB, member of RAS oncogene family like 2B" Q9UNT1 22 50767501-50783662 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 99.4;Respiratory ciliated cells: 188.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA042642, HPA042700, HPA044007" Approved Approved Vesicles,Centrosome NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" Centrosome Vesicles "HPA042642: , HPA042700: AB_2678120, HPA044007: AB_2678770" "unprognostic (2.09e-1)" "unprognostic (1.47e-2)" "unprognostic (1.86e-3)" "prognostic favorable (5.58e-4)" "unprognostic (7.85e-2)" "unprognostic (9.98e-2)" "prognostic unfavorable (4.58e-5)" "unprognostic (3.14e-1)" "unprognostic (6.97e-2)" "unprognostic (7.33e-2)" "unprognostic (1.19e-2)" "unprognostic (7.51e-2)" "unprognostic (3.71e-3)" "unprognostic (7.43e-3)" "unprognostic (1.37e-1)" "unprognostic (1.25e-1)" "unprognostic (8.37e-3)" 13.2 12.9 18.1 18.6 18.8 14.4 15.8 18.1 22.4 23.9 73.6 16.5 12.5 21.7 90.3 13.3 66.6 14.5 10.2 23.3 17.0 17.7 12.2 21.8 23.1 23.3 33.2 22.5 16.3 14.6 26.7 11.6 17.9 16.2 16.7 30.2 16.8 16.9 8.8 22.2 15.6 15.6 21.9 19.3 14.5 23.1 20.1 21.6 28.2 4.6 20.3 17.0 15.7 18.5 23.0 20.4 34.1 26.7 37.3 29.6 25.0 16.7 18.5 13.2 18.1 5.8 19.7 14.7 14.7 24.1 21.6 29.5 15.8 19.6 14.2 13.3 23.2 12.8 40.2 15.1 15.4 36.1 13.0 25.3 26.2 17.5 21.9 39.2 15.0 26.0 9.9 17.9 26.7 28.8 18.2 15.9 13.2 14.0 15.0 30.1 19.8 16.1 25.9 22.4 14.6 26.5 20.5 17.8 13.4 23.4 17.7 11.2 23.2 12.6 25.1 10.9 11.4 15.2 7.4 7.2 23.8 8.8 18.1 1.8 14.4 13.1 21.4 23.5 15.5 15.2 16.4 17.3 15.7 19.2 18.7 18.3 5.4 15.9 28.4 18.0 18.6 14.7 18.1 18.8 18.1 22.4 23.3 17.0 23.3 33.2 17.9 21.9 20.1 18.5 6.2 12.8 13.4 14.4 16.8 5.4 13.4 13.3 15.9 15.2 13.3 11.8 5.1 12.8 24.1 22.0 31.3 12.1 16.2 10.6 13.7 21.3 25.7 99.4 11.2 7.2 5.4 9.9 25.7 10.8 11.1 11.4 9.7 8.6 3.8 22.1 5.3 8.9 12.0 16.8 18.9 8.0 22.4 10.1 6.9 24.2 14.0 8.4 17.8 4.7 14.4 13.9 36.0 7.1 15.1 10.4 4.9 10.9 8.0 7.3 8.6 16.3 188.6 40.0 6.6 15.0 14.8 38.8 27.0 8.8 5.7 6.7 16.0 11.9 10.7 6.5 RAD1 "HRAD1, REC1" ENSG00000113456 "RAD1 checkpoint DNA exonuclease" O60671 5 34905260-34918989 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006692 Approved Approved Nucleoplasm,Vesicles NA Yes "Cluster 6: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 20: HeLa - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Vesicles" "HPA006692: AB_2667645" "prognostic unfavorable (6.30e-4)" "unprognostic (1.85e-2)" "unprognostic (9.40e-2)" "unprognostic (1.98e-3)" "unprognostic (2.00e-1)" "unprognostic (2.38e-2)" "prognostic unfavorable (1.06e-5)" "unprognostic (1.22e-2)" "unprognostic (2.25e-3)" "unprognostic (1.61e-3)" "unprognostic (2.57e-1)" "unprognostic (2.57e-1)" "unprognostic (2.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.11e-1)" "unprognostic (3.12e-3)" 3.5 8.1 3.2 4.8 3.5 8.4 5.8 3.9 4.6 6.8 5.3 4.1 4.9 5.6 5.4 4.9 3.9 4.6 8.9 3.8 4.6 5.1 4.3 7.5 8.9 3.5 2.7 5.7 4.4 5.1 3.5 8.1 3.2 6.8 4.3 8.7 4.9 4.8 10.9 6.7 4.8 4.6 1.9 4.9 4.8 7.9 3.4 6.3 6.3 8.6 6.2 5.2 4.7 3.8 8.5 10.2 12.3 20.5 7.9 9.4 17.2 15.1 12.0 13.0 10.6 12.2 12.3 25.0 5.2 11.2 15.7 8.4 12.6 7.6 14.4 10.1 12.7 12.9 34.0 8.0 11.9 16.5 11.9 7.8 7.3 13.9 9.3 6.1 6.2 11.0 22.7 13.2 11.2 10.2 19.6 13.9 15.4 6.0 15.7 17.1 24.0 8.6 6.7 9.0 12.4 13.3 30.0 19.9 13.3 7.6 12.5 14.8 6.2 17.9 13.3 9.7 14.4 7.9 13.8 20.3 11.1 28.6 12.5 7.4 2.9 6.5 5.3 2.8 6.9 8.6 5.8 7.6 3.1 9.1 8.2 6.8 1.6 4.5 2.8 6.9 4.9 2.6 3.2 3.5 3.9 4.6 3.8 4.6 3.5 2.7 3.2 1.9 3.4 3.8 11.5 22.4 43.2 5.9 18.3 29.2 20.2 29.3 13.1 25.3 23.9 18.4 25.7 14.3 21.3 20.2 27.1 82.3 20.4 11.9 19.6 18.1 22.0 13.1 16.6 14.1 13.1 28.2 6.6 22.5 54.4 18.7 6.1 12.0 21.5 39.1 10.0 14.8 23.4 23.5 9.0 12.7 30.5 12.0 19.3 16.8 25.1 13.1 17.8 6.5 12.7 23.9 9.2 7.5 9.1 17.8 13.8 21.8 18.0 21.9 13.4 16.4 14.6 35.6 13.1 19.6 19.4 72.5 58.6 15.6 28.6 80.6 22.3 27.4 13.0 25.8 RAD51C "FANCO, RAD51L2" ENSG00000108384 "RAD51 paralog C" O43502 17 58692573-58735611 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 117.7;Spermatocytes: 140.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 319.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045198 Supported "Nucleoplasm,Vesicles,Cell Junctions,Mitochondria,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Mitochondria, Cytosol" "Vesicles, Cell Junctions" "HPA045198: AB_2679250" "unprognostic (5.39e-3)" "unprognostic (2.39e-2)" "unprognostic (1.23e-2)" "unprognostic (6.20e-2)" "unprognostic (1.83e-1)" "unprognostic (4.59e-2)" "prognostic unfavorable (8.68e-5)" "unprognostic (3.65e-2)" "unprognostic (2.91e-2)" "unprognostic (1.03e-2)" "prognostic favorable (5.33e-4)" "unprognostic (2.55e-1)" "unprognostic (2.62e-2)" "unprognostic (7.62e-2)" "unprognostic (2.41e-1)" "unprognostic (9.52e-2)" "unprognostic (2.42e-2)" 10.8 20.2 15.5 10.0 15.7 23.1 15.3 19.0 18.4 10.8 13.4 12.4 7.5 12.6 22.0 13.0 11.2 11.0 25.7 16.4 15.0 12.8 13.3 8.8 22.0 14.9 13.8 12.5 10.6 20.1 10.5 15.1 16.0 17.4 14.5 13.5 10.7 12.0 18.3 10.6 8.7 13.8 13.2 12.2 11.6 20.2 14.6 21.2 12.3 17.3 19.1 10.9 8.6 18.2 63.7 72.1 43.3 48.5 22.9 19.6 100.1 34.2 14.5 43.5 55.3 31.0 39.3 37.4 48.9 23.5 58.8 23.3 59.5 46.6 81.7 91.6 123.0 53.0 84.6 119.4 23.3 69.1 45.0 12.1 42.2 47.8 38.6 24.0 50.0 60.9 83.6 48.5 37.0 319.1 96.8 95.3 12.1 42.5 66.5 62.1 69.5 69.8 26.9 39.6 54.3 49.6 27.3 12.0 53.5 11.1 39.2 71.6 16.5 37.6 100.1 34.3 42.4 44.1 187.2 111.5 38.3 67.1 42.0 27.6 9.2 12.5 15.6 14.3 15.2 18.0 16.9 17.2 15.9 17.3 18.2 17.4 5.1 15.0 12.5 14.3 27.1 11.0 15.5 15.7 19.0 18.4 16.4 15.0 14.9 13.8 16.0 13.2 14.6 18.2 20.5 19.2 13.9 10.1 20.5 11.9 18.7 42.9 15.9 15.0 25.1 34.0 63.7 7.2 20.9 16.5 6.2 67.8 15.0 7.1 58.7 25.7 117.7 17.3 13.0 19.3 6.7 43.8 21.5 18.6 94.1 19.8 7.1 13.0 22.9 23.3 15.7 15.7 33.4 16.8 17.7 11.7 32.6 16.1 47.7 65.4 17.4 21.8 24.9 13.1 18.7 31.3 21.6 23.1 22.8 13.0 10.4 15.4 28.5 17.2 5.7 24.6 14.1 26.9 32.9 14.7 23.9 140.7 98.3 15.9 10.7 36.3 20.5 28.2 15.3 13.9 RAET1G ULBP5 ENSG00000203722 "Retinoic acid early transcript 1G" Q6H3X3 6 149916878-149923121 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 8.4;esophagus: 15.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 42.9;Club cells: 14.8;Ionocytes: 12.2;Respiratory ciliated cells: 23.3;Squamous epithelial cells: 8.9;Urothelial cells: 8.1" "Group enriched" "Detected in many" 4 "cervical cancer: 4.5;head and neck cancer: 4.7;lung cancer: 1.2;thyroid cancer: 1.5;urothelial cancer: 4.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 29.5;hTCEpi: 22.6;SiHa: 11.9;U-87 MG: 9.3" "HPA062673, HPA066741" Supported "Vesicles,Plasma membrane" "Secreted - unknown location" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" "HPA062673: , HPA066741: " "unprognostic (4.46e-3)" "unprognostic (4.92e-2)" "unprognostic (1.95e-1)" "unprognostic (1.21e-1)" "unprognostic (2.87e-3)" "unprognostic (1.49e-1)" "unprognostic (4.61e-3)" "prognostic unfavorable (5.35e-4)" "unprognostic (3.05e-1)" "unprognostic (1.57e-1)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "unprognostic (1.33e-1)" "unprognostic (1.49e-2)" "unprognostic (2.48e-1)" "unprognostic (8.85e-2)" "unprognostic (9.11e-2)" 2.8 8.4 0.4 0.4 0.3 0.0 0.6 0.0 0.4 4.1 0.0 0.2 0.1 0.3 0.7 15.1 0.6 0.7 0.6 0.4 0.3 0.9 0.1 0.5 0.1 0.3 0.6 0.7 0.1 0.2 0.3 0.1 0.1 0.7 0.1 0.1 3.7 1.0 0.2 2.7 0.2 0.6 0.0 0.1 0.4 0.3 0.7 0.0 0.4 0.1 1.1 1.8 6.0 0.0 1.0 1.4 0.0 1.7 2.3 1.7 0.0 0.8 3.0 1.3 1.9 0.0 1.5 0.0 0.6 1.7 1.4 2.7 0.9 5.3 1.1 0.3 1.6 0.5 29.5 0.0 0.7 0.0 0.0 3.3 22.6 3.5 1.7 1.5 0.3 0.7 0.3 0.2 0.6 1.3 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 1.0 3.2 0.3 0.3 11.9 0.5 0.0 0.1 0.4 0.4 1.6 0.6 0.5 1.6 0.8 0.0 0.0 0.0 9.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.4 0.4 0.3 0.3 0.6 0.1 0.0 0.7 0.0 1.4 0.0 0.0 0.0 0.0 3.1 5.1 42.9 2.8 0.0 0.4 0.4 0.1 1.5 14.8 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.4 0.1 1.3 0.0 0.0 0.0 1.3 0.0 1.9 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 12.2 0.0 0.7 0.1 0.9 0.0 3.6 0.0 0.0 0.8 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.4 0.0 0.0 23.3 0.0 0.0 0.2 1.1 0.0 0.3 8.9 1.7 0.1 0.3 0.5 0.0 8.1 RAET1L ENSG00000155918 "Retinoic acid early transcript 1L" Q5VY80 6 150018334-150025532 "Predicted membrane proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 58.1;vagina: 17.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.4;Basal prostatic cells: 11.3;Basal respiratory cells: 6.4;Prostatic glandular cells: 7.1;Squamous epithelial cells: 7.2;Suprabasal keratinocytes: 17.0;Urothelial cells: 8.1" "Group enriched" "Detected in many" 4 "cervical cancer: 4.8;head and neck cancer: 10.1;lung cancer: 4.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HaCaT: 14.3" HPA066741 Supported "Vesicles,Plasma membrane" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Plasma membrane" "HPA066741: " "unprognostic (1.80e-1)" "unprognostic (1.63e-1)" "unprognostic (2.15e-1)" "unprognostic (1.84e-1)" "unprognostic (4.24e-3)" "unprognostic (1.51e-1)" "prognostic unfavorable (4.09e-4)" "unprognostic (8.34e-2)" "unprognostic (1.37e-1)" "unprognostic (2.26e-2)" "unprognostic (7.48e-2)" "unprognostic (1.46e-2)" "unprognostic (2.49e-1)" "unprognostic (1.29e-1)" "unprognostic (5.14e-2)" "unprognostic (7.43e-3)" 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 8.1 0.0 0.0 0.0 0.0 0.0 58.1 0.0 0.1 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.1 5.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 5.2 0.3 17.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 1.2 0.0 0.7 14.3 0.3 0.4 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.4 0.0 0.0 0.0 2.6 0.7 0.0 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.2 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 11.3 6.4 1.2 0.0 0.4 0.3 0.0 0.0 2.9 0.0 0.0 0.0 0.0 1.0 0.0 2.8 0.8 0.5 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 7.1 0.0 0.2 0.9 0.0 0.0 0.0 0.4 0.0 0.1 7.2 17.0 0.0 0.0 0.0 0.1 8.1 RALBP1 "RIP, RIP1, RLIP76" ENSG00000017797 "RalA binding protein 1" Q15311 18 9475009-9538114 "Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins, Transporters" Transport "GTPase activation, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Collecting duct cells: 480.1;Extravillous trophoblasts: 518.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 10 "neutrophil: 195.6" "Lineage enriched" "Detected in all" 10 "granulocytes: 195.6" "Cell line enhanced" "Detected in all" "OE19: 239.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046010, HPA046651" Approved Approved "Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "Nuclear membrane, Vesicles" "CAB046010: AB_11126824, HPA046651: AB_2679738" "unprognostic (1.23e-1)" "unprognostic (5.84e-3)" "unprognostic (1.58e-1)" "unprognostic (1.74e-2)" "unprognostic (8.24e-2)" "unprognostic (1.12e-1)" "unprognostic (5.72e-2)" "unprognostic (9.90e-2)" "unprognostic (1.53e-1)" "prognostic favorable (8.47e-4)" "unprognostic (4.03e-3)" "unprognostic (1.76e-1)" "prognostic favorable (5.39e-6)" "unprognostic (1.28e-1)" "unprognostic (3.16e-2)" "unprognostic (2.47e-1)" "unprognostic (1.26e-1)" 29.7 20.4 42.7 23.4 44.1 30.7 27.8 45.8 82.2 26.8 38.6 34.1 18.7 22.1 23.5 50.3 24.8 20.3 28.5 40.7 45.1 42.7 19.9 22.6 24.0 44.1 48.0 26.3 15.4 47.9 16.8 31.4 44.4 32.6 25.4 13.5 25.0 48.2 38.5 75.9 20.4 21.1 43.6 26.5 25.7 13.0 45.3 29.3 22.9 32.5 25.4 33.8 33.3 45.1 58.9 37.6 34.2 39.0 38.3 60.7 43.3 67.7 38.1 35.6 38.0 42.6 57.5 70.5 47.0 64.8 50.2 32.8 48.1 52.7 44.2 71.4 38.5 38.5 34.6 32.7 31.2 114.8 43.0 42.0 52.2 49.6 48.7 47.7 60.6 64.6 53.7 67.7 56.2 46.3 70.7 50.9 25.4 239.5 31.9 93.6 59.4 54.2 48.4 80.7 44.7 34.8 58.2 52.8 30.9 52.3 32.9 53.8 67.4 105.0 76.9 72.3 81.9 38.7 42.9 77.9 45.6 53.4 40.5 13.0 9.6 15.7 10.3 10.6 8.7 9.9 8.7 8.8 8.7 7.5 7.3 9.4 195.6 14.8 17.8 19.8 6.4 4.5 42.7 44.1 45.8 82.2 40.7 45.1 44.1 48.0 44.4 43.6 45.3 45.1 101.8 57.7 35.7 15.3 48.0 156.4 80.9 59.9 112.7 42.6 96.0 102.2 64.8 88.6 64.6 480.1 29.2 104.2 70.9 122.6 123.3 119.4 16.1 99.1 82.6 86.9 74.2 175.7 25.4 90.7 518.6 71.6 56.1 179.4 40.5 85.8 78.9 88.3 70.1 52.2 26.7 87.7 109.9 92.8 69.7 9.5 72.7 78.4 58.7 20.6 99.6 47.6 83.4 17.1 25.3 166.3 78.2 87.3 63.2 174.4 61.0 115.0 38.6 37.3 65.7 76.8 105.6 66.7 80.0 149.6 242.5 44.6 62.6 128.4 90.1 216.4 RALY "HNRPCL2, P542" ENSG00000125970 "RALY heterogeneous nuclear ribonucleoprotein" Q9UKM9 20 33993646-34108308 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040971, HPA043614" Enhanced Enhanced Nucleoplasm,Vesicles NA NA 9400 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA040971: AB_2677230, HPA043614: AB_2678581" "unprognostic (2.06e-1)" "unprognostic (9.54e-3)" "unprognostic (3.72e-2)" "unprognostic (2.28e-1)" "unprognostic (4.68e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (3.60e-4)" "unprognostic (3.06e-1)" "unprognostic (1.27e-1)" "unprognostic (3.66e-1)" "unprognostic (4.20e-2)" "unprognostic (8.59e-2)" "unprognostic (3.29e-2)" "unprognostic (2.88e-2)" "unprognostic (8.61e-3)" "unprognostic (1.64e-2)" "unprognostic (8.80e-2)" 109.7 65.4 72.1 90.4 83.2 189.2 98.2 82.6 79.3 108.9 81.8 127.2 109.8 96.9 41.6 119.6 84.8 70.7 143.2 67.6 77.4 104.4 68.3 117.4 116.9 87.8 81.9 101.2 78.2 62.1 55.6 77.6 84.2 88.3 87.6 55.0 105.3 64.3 178.4 114.6 117.7 70.1 83.7 109.6 101.9 116.5 80.9 161.7 125.5 106.0 99.9 99.3 98.4 100.7 250.4 138.1 247.6 193.9 115.3 110.3 210.1 172.9 136.0 215.1 183.0 375.8 204.0 204.3 238.7 140.6 290.9 259.4 135.8 252.7 119.2 132.2 119.3 468.3 81.4 375.4 147.8 236.2 215.0 122.4 141.6 161.9 175.4 160.7 203.0 245.6 201.7 300.9 135.8 185.9 589.3 266.6 137.5 306.0 277.2 344.4 360.6 250.7 126.7 135.4 235.8 266.6 271.8 248.4 376.6 125.8 256.2 234.4 167.5 414.4 270.7 212.3 206.6 310.7 308.3 353.5 213.0 169.9 201.3 139.3 110.7 221.3 138.8 137.1 100.2 96.5 122.2 150.4 135.3 99.6 107.8 104.0 173.3 186.1 195.5 110.0 141.4 165.3 72.1 83.2 82.6 79.3 67.6 77.4 87.8 81.9 84.2 83.7 80.9 100.7 91.8 54.5 61.3 23.2 98.3 79.2 126.9 102.3 74.6 24.2 74.9 67.8 63.4 58.6 61.7 55.2 18.8 161.3 118.3 287.4 127.2 149.1 48.1 36.4 48.5 92.1 93.0 87.9 19.3 160.5 227.7 78.2 70.8 66.9 59.7 69.7 76.8 39.8 159.6 8.4 14.6 143.2 95.6 112.2 118.1 46.7 65.6 96.9 115.6 50.6 151.3 62.6 163.7 15.6 57.1 190.3 270.7 62.1 206.4 157.5 220.7 107.3 38.8 36.3 111.7 47.7 97.7 106.6 121.1 103.7 80.7 171.4 117.2 51.6 178.6 176.2 RAMP2 ENSG00000131477 "Receptor activity modifying protein 2" O60895 17 42758447-42763041 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 1066.8;Endothelial cells: 562.9;Hepatic stellate cells: 344.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 21 "plasmacytoid DC: 2.9" "Lineage enriched" "Detected in single" 21 "dendritic cells: 2.9" "Cell line enhanced" "Detected in many" "ASC diff: 120.4;EFO-21: 80.5;HUVEC TERT2: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052020 Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA052020: AB_2681697" "unprognostic (8.64e-2)" "unprognostic (2.12e-2)" "unprognostic (8.03e-2)" "unprognostic (1.16e-2)" "unprognostic (5.24e-2)" "unprognostic (4.13e-3)" "unprognostic (2.68e-2)" "unprognostic (1.04e-1)" "unprognostic (4.50e-2)" "unprognostic (5.18e-2)" "unprognostic (1.02e-2)" "unprognostic (6.79e-2)" "unprognostic (1.28e-2)" "unprognostic (6.96e-3)" "unprognostic (4.42e-2)" "unprognostic (2.20e-1)" "unprognostic (1.25e-1)" 190.0 29.0 60.4 19.2 61.8 0.1 168.9 61.7 72.3 100.7 67.7 35.7 12.5 63.1 27.8 25.1 51.7 39.6 123.2 59.3 65.8 70.5 16.7 163.3 26.2 65.7 68.1 33.0 17.1 23.8 20.8 97.0 72.7 42.1 21.1 4.1 45.9 27.5 43.3 55.9 44.1 72.6 62.7 40.2 33.9 11.9 66.6 11.4 71.7 98.7 24.5 45.9 49.6 62.4 0.1 1.1 4.9 0.1 120.4 6.2 4.0 0.9 2.1 10.2 4.9 11.5 0.1 0.0 80.5 3.0 0.5 0.0 4.6 0.1 8.9 0.0 0.2 0.0 0.7 3.7 3.0 0.0 0.0 4.2 0.1 1.8 0.4 3.5 37.6 1.5 0.1 0.2 0.6 0.0 0.6 0.8 23.3 0.0 0.0 0.1 0.1 0.0 0.6 0.6 4.8 9.8 2.9 0.0 17.3 4.8 1.2 3.2 6.7 19.3 7.1 0.4 2.4 0.0 0.1 0.3 0.0 0.1 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.1 0.0 60.4 61.8 61.7 72.3 59.3 65.8 65.7 68.1 72.7 62.7 66.6 62.4 1066.8 0.0 5.7 1.6 6.2 34.4 5.4 0.9 9.6 0.6 24.0 24.8 2.2 0.0 1.0 3.7 0.0 1.1 3.7 0.1 3.9 0.6 1.6 22.2 52.8 562.9 4.2 0.0 0.2 0.7 1.7 126.9 3.1 38.5 0.0 1.4 344.8 1.3 3.4 0.0 1.0 0.2 20.3 8.4 40.5 3.6 38.8 4.1 23.2 45.0 2.6 15.5 0.0 1.5 0.3 0.0 0.0 21.8 5.2 4.8 0.0 1.0 0.1 1.8 6.6 10.5 26.3 26.6 59.1 2.6 27.6 1.5 4.0 14.0 0.1 4.3 RANBP2 "ADANE, ANE1, NUP358" ENSG00000153201 "RAN binding protein 2" P49792 2 108719482-108785809 "Cancer-related genes, Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport, Ubl conjugation pathway" "RNA-binding, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018437, HPA023960, CAB034063, HPA049497, HPA051675, HPA067564" Supported Supported "Nucleoplasm,Nuclear membrane,Vesicles" NA NA 160000 "Cluster 38: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nuclear membrane" "Nucleoplasm, Vesicles" "CAB034063: AB_2176784, HPA018437: AB_2620151, HPA023960: AB_2671385, HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (2.51e-1)" "unprognostic (3.99e-2)" "unprognostic (1.22e-1)" "unprognostic (4.37e-2)" "unprognostic (1.28e-2)" "unprognostic (9.30e-2)" "unprognostic (5.47e-2)" "unprognostic (2.91e-1)" "unprognostic (4.02e-2)" "unprognostic (2.54e-1)" "unprognostic (4.23e-1)" "unprognostic (5.23e-2)" "unprognostic (1.62e-2)" "unprognostic (8.74e-2)" "unprognostic (3.08e-1)" "unprognostic (3.40e-2)" "unprognostic (2.53e-1)" 20.3 24.3 8.6 16.3 11.6 42.1 19.7 14.4 17.1 18.1 20.3 15.6 13.4 17.7 20.5 14.3 14.6 13.7 14.9 11.8 9.4 18.1 17.4 14.0 18.6 9.2 8.1 24.4 20.2 30.1 21.5 16.5 9.5 20.9 15.2 26.5 16.4 17.2 30.3 17.2 13.4 15.2 8.6 15.0 17.6 21.3 8.2 23.3 28.4 23.6 18.0 16.9 12.1 12.2 40.5 24.2 34.1 31.0 38.7 34.5 32.9 35.5 28.0 28.7 25.1 60.7 18.9 63.2 26.8 37.2 35.3 33.1 58.9 36.9 41.5 38.9 28.5 65.9 30.3 43.2 22.5 77.9 21.3 29.1 27.5 44.9 34.7 28.3 44.5 27.1 71.9 34.0 38.4 22.3 34.8 31.6 43.0 20.3 28.7 32.3 52.3 30.7 25.3 49.6 49.4 22.6 31.5 26.7 34.7 20.4 17.2 35.4 53.5 29.8 39.6 21.2 40.2 27.9 44.4 55.8 23.1 34.4 23.5 5.4 2.6 2.7 3.7 1.7 4.1 2.7 3.0 3.4 2.2 2.7 2.9 3.3 3.9 2.2 3.6 2.6 2.7 1.4 8.6 11.6 14.4 17.1 11.8 9.4 9.2 8.1 9.5 8.6 8.2 12.2 54.5 76.9 85.3 48.6 91.5 55.7 34.5 39.1 61.5 51.2 34.1 25.8 103.9 38.6 63.0 58.8 73.0 28.8 96.1 28.9 1.9 34.7 77.3 83.6 65.3 55.7 106.4 50.5 125.5 50.9 17.5 56.5 68.3 142.1 84.9 52.2 31.4 56.6 47.9 32.0 92.2 59.5 44.7 44.9 80.7 32.9 38.5 114.0 48.0 55.3 57.0 20.0 34.0 44.2 80.0 41.5 29.9 56.1 118.4 44.1 28.8 15.6 67.0 40.5 46.0 56.9 59.0 78.3 65.4 53.3 67.8 40.6 104.8 25.3 38.3 38.7 RANBP6 ENSG00000137040 "RAN binding protein 6" O60518 9 6011025-6015625 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043748, HPA052684" Approved Supported Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 52: Non-specific - Transcription" Vesicles "HPA043748: AB_10796796, HPA052684: AB_2681913" "unprognostic (1.47e-2)" "unprognostic (8.86e-2)" "unprognostic (1.70e-1)" "unprognostic (6.01e-2)" "unprognostic (3.63e-2)" "unprognostic (1.30e-1)" "unprognostic (3.37e-1)" "unprognostic (3.21e-2)" "unprognostic (1.34e-1)" "unprognostic (8.22e-2)" "unprognostic (3.81e-2)" "unprognostic (1.89e-2)" "prognostic favorable (1.34e-7)" "unprognostic (2.42e-1)" "unprognostic (1.91e-1)" "unprognostic (3.04e-1)" "unprognostic (2.61e-1)" 8.6 11.4 8.3 12.9 8.8 31.0 11.4 11.5 12.4 7.7 18.4 7.1 7.5 8.8 7.0 7.9 7.3 7.6 12.4 9.3 10.8 13.4 15.2 8.4 17.0 11.2 9.7 9.6 7.8 13.6 5.0 8.9 11.9 9.7 7.1 21.6 8.6 8.5 16.3 9.9 8.6 10.3 9.2 13.1 11.1 5.9 10.0 19.6 12.0 16.1 16.2 8.7 5.6 10.3 25.1 13.6 27.2 23.4 23.6 18.6 14.6 30.9 21.9 26.8 21.6 7.5 7.7 33.5 8.4 24.7 13.1 14.0 24.2 28.2 29.7 80.1 13.9 88.3 53.0 15.6 13.9 34.2 17.9 20.2 15.2 16.5 16.3 21.1 31.3 30.1 6.9 27.3 25.8 8.4 24.3 54.8 12.3 9.0 11.0 25.6 16.7 15.7 28.1 17.6 13.2 19.9 14.7 11.0 8.7 22.3 17.7 23.0 37.6 25.1 14.9 12.4 29.4 16.3 27.8 31.5 14.4 19.8 9.3 5.1 4.5 3.7 2.6 6.3 2.5 2.5 3.8 2.8 2.7 1.9 4.4 4.2 1.3 2.8 5.2 3.1 5.2 2.9 8.3 8.8 11.5 12.4 9.3 10.8 11.2 9.7 11.9 9.2 10.0 10.3 11.3 9.6 8.1 8.8 11.5 10.3 6.6 10.1 13.1 18.0 8.1 5.6 24.4 8.6 16.3 11.0 2.1 8.8 12.0 4.1 7.9 8.6 1.6 12.2 16.5 13.1 9.5 8.6 15.9 10.9 4.1 8.3 16.8 17.7 10.8 10.1 10.0 13.7 4.4 11.8 19.0 3.2 2.0 10.5 6.0 1.2 6.5 7.2 1.8 8.4 7.2 15.9 9.2 3.0 20.5 7.5 3.8 6.8 11.8 5.7 1.8 12.5 8.7 23.1 0.0 11.6 10.2 10.1 9.3 9.8 9.5 6.6 13.3 12.7 4.8 7.3 RANGAP1 "Fug1, KIAA1835, SD" ENSG00000100401 "Ran GTPase activating protein 1" P46060 22 41244779-41286187 "Plasma proteins, Predicted intracellular proteins, Transporters" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Late spermatids: 1717.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004293, HPA050110, HPA062034" Supported Enhanced "Nuclear membrane,Vesicles,Cytosol" Yes Yes 75000 "Cluster 27: Non-specific - Gene expression" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Nuclear membrane" "Vesicles, Cytosol" "CAB004293: AB_2176987, HPA050110: AB_2681018, HPA062034: AB_2684667" "unprognostic (1.30e-2)" "unprognostic (3.16e-2)" "unprognostic (1.66e-1)" "unprognostic (7.97e-2)" "unprognostic (2.57e-1)" "unprognostic (2.54e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (8.28e-3)" "unprognostic (8.09e-2)" "unprognostic (9.87e-2)" "unprognostic (5.84e-2)" "unprognostic (7.56e-2)" "unprognostic (7.07e-3)" "prognostic favorable (5.39e-4)" "unprognostic (2.06e-1)" "unprognostic (2.74e-1)" "unprognostic (2.68e-1)" 27.5 72.9 78.2 26.0 86.0 48.1 29.6 70.8 102.3 34.4 47.7 29.2 18.1 24.9 12.0 79.8 23.6 17.2 45.1 79.5 85.2 43.9 88.0 41.6 30.6 102.7 77.9 32.5 60.9 12.7 57.4 22.8 105.1 39.3 13.2 32.7 38.0 17.6 43.0 96.9 30.6 17.5 68.7 42.3 39.6 178.1 82.0 40.4 34.4 14.2 31.8 34.7 45.4 109.1 228.0 112.2 75.9 77.3 38.8 31.4 85.9 194.5 103.8 182.8 98.4 135.9 71.9 118.0 154.0 137.4 94.8 203.0 135.5 145.4 125.2 95.7 199.2 103.3 115.0 107.9 46.7 171.6 72.5 30.0 69.5 132.2 123.4 67.6 102.1 45.0 127.7 83.3 111.9 186.1 96.3 130.0 84.5 217.6 127.6 118.8 73.4 126.0 72.5 123.7 66.6 44.1 139.1 117.7 71.7 74.6 72.2 64.4 146.5 141.7 138.5 78.6 154.6 60.1 92.8 124.2 99.3 119.3 82.0 2.7 7.6 6.9 8.1 9.0 9.5 5.9 8.2 7.8 5.6 6.4 7.4 5.9 2.0 5.9 12.9 5.9 9.5 8.2 78.2 86.0 70.8 102.3 79.5 85.2 102.7 77.9 105.1 68.7 82.0 109.1 10.9 3.2 20.9 8.5 15.0 23.1 22.2 10.9 18.2 16.0 22.4 16.9 19.6 25.8 9.6 9.2 14.6 22.7 20.3 22.9 3.9 33.3 270.7 21.0 14.7 16.1 25.0 16.6 28.3 20.3 35.3 13.3 25.5 25.1 6.3 74.4 8.9 21.8 16.6 15.2 20.8 19.1 16.2 13.9 20.9 1717.0 14.9 16.8 12.4 5.6 8.9 10.1 14.4 6.0 32.2 39.8 5.7 12.0 25.8 37.4 7.1 13.1 11.4 26.4 0.0 6.8 18.2 25.6 17.7 38.8 31.0 23.7 24.3 42.5 24.8 23.3 RAPGEF1 "C3G, GRF2" ENSG00000107263 "Rap guanine nucleotide exchange factor 1" Q13905 9 131576770-131740074 "Plasma proteins, Predicted intracellular proteins" Neurogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 228.6" "Cell type enhanced" "Detected in all" "Horizontal cells: 131.2;Langerhans cells: 108.6;Microglial cells: 123.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006426, HPA075984" Enhanced Supported Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" Vesicles "HPA006426: AB_1856070, HPA075984: AB_2686771" "unprognostic (1.00e-1)" "unprognostic (8.19e-2)" "unprognostic (2.12e-2)" "unprognostic (2.43e-2)" "unprognostic (2.34e-1)" "unprognostic (2.38e-1)" "unprognostic (4.11e-2)" "unprognostic (1.74e-1)" "unprognostic (5.50e-2)" "unprognostic (6.04e-2)" "unprognostic (1.94e-2)" "unprognostic (1.62e-1)" "prognostic favorable (1.18e-5)" "unprognostic (5.66e-2)" "unprognostic (1.99e-2)" "unprognostic (1.49e-1)" "unprognostic (3.73e-2)" 37.3 24.0 41.4 53.9 72.6 53.2 26.8 27.0 37.1 20.4 37.9 31.9 23.9 25.6 8.0 23.6 25.5 23.7 57.8 40.8 40.2 23.0 23.0 43.3 56.1 35.8 36.9 16.3 47.8 20.1 16.4 56.4 32.3 21.5 23.4 27.5 20.2 21.4 228.6 21.9 35.3 30.4 25.6 41.9 29.1 15.9 43.8 35.1 22.7 104.8 63.1 25.8 18.2 20.2 34.5 39.4 39.1 39.6 39.1 42.0 149.2 29.0 59.0 33.0 23.6 49.0 22.1 61.9 35.6 58.8 70.7 61.4 45.1 40.5 16.4 144.6 18.6 18.3 67.2 26.2 32.8 76.1 80.4 32.2 73.0 43.3 51.0 33.1 60.4 70.8 49.7 119.1 43.4 35.7 54.0 27.0 39.6 34.1 35.2 53.0 91.0 86.8 14.9 41.1 33.0 32.9 42.5 39.8 42.3 39.0 38.1 63.1 64.4 88.1 36.7 56.4 44.7 39.8 37.3 122.0 41.9 32.0 21.6 3.1 1.2 1.6 3.4 2.2 2.0 4.9 2.3 2.3 1.4 2.9 0.5 1.5 1.3 1.3 2.4 1.6 1.8 1.6 41.4 72.6 27.0 37.1 40.8 40.2 35.8 36.9 32.3 25.6 43.8 20.2 73.5 6.4 13.8 27.1 35.6 18.7 9.3 10.9 5.2 19.5 10.8 13.5 16.2 14.3 12.3 5.5 14.6 22.7 49.7 23.3 5.9 8.2 2.6 13.0 9.4 43.0 12.1 1.7 47.5 18.6 35.3 11.8 17.9 17.8 20.3 14.0 22.5 17.4 26.4 131.2 66.6 14.9 8.2 23.9 108.6 2.5 8.7 51.6 32.0 123.7 59.8 19.7 27.8 61.3 24.7 17.1 19.1 12.0 88.0 11.7 16.8 9.2 16.7 13.4 6.6 13.4 10.3 5.1 11.8 5.6 11.4 51.7 31.0 5.8 14.0 10.8 RASA2 GAP1M ENSG00000155903 "RAS p21 protein activator 2" Q15283 3 141487027-141615344 "Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 196.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035374, HPA035375" Approved Approved Vesicles "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" Vesicles "HPA035374: AB_10602122, HPA035375: AB_2674596" "unprognostic (1.85e-1)" "unprognostic (8.11e-2)" "unprognostic (1.48e-1)" "unprognostic (2.38e-2)" "unprognostic (1.18e-1)" "unprognostic (3.36e-3)" "unprognostic (9.62e-3)" "unprognostic (2.57e-1)" "unprognostic (1.38e-1)" "unprognostic (9.21e-2)" "unprognostic (4.23e-2)" "unprognostic (8.93e-2)" "prognostic unfavorable (7.62e-7)" "unprognostic (1.17e-1)" "unprognostic (2.56e-1)" "unprognostic (1.61e-1)" "prognostic favorable (4.34e-5)" 7.3 4.7 5.1 15.4 6.0 21.9 10.0 7.1 6.4 9.8 3.2 6.6 5.3 8.4 7.3 7.3 7.8 6.7 4.6 5.3 4.9 5.8 5.1 9.7 21.3 4.0 3.6 9.7 5.2 4.4 6.2 8.3 3.5 6.5 7.2 14.6 8.1 5.0 3.8 11.2 8.5 6.0 3.1 12.4 5.4 4.7 4.7 13.3 6.0 3.3 17.2 8.8 8.8 5.6 24.6 4.5 9.5 7.2 10.2 12.6 13.5 17.4 34.0 11.0 13.5 10.5 7.9 15.6 11.7 15.2 10.6 10.0 6.8 7.5 20.0 8.5 6.7 8.4 3.8 3.8 5.4 16.1 21.0 7.3 6.6 10.0 11.8 13.3 14.1 13.1 7.7 19.7 11.0 3.6 21.2 13.0 11.1 8.1 3.2 7.9 16.0 19.5 10.9 8.7 3.3 6.9 13.8 12.1 13.0 9.8 6.0 12.0 11.9 12.9 5.9 18.1 7.8 31.9 10.0 20.9 11.3 10.8 6.4 12.8 4.9 5.3 14.8 5.0 14.8 8.9 13.2 15.3 4.6 13.5 21.6 17.2 19.2 15.7 8.9 3.6 13.2 8.0 5.1 6.0 7.1 6.4 5.3 4.9 4.0 3.6 3.5 3.1 4.7 5.6 24.2 44.8 23.6 59.4 55.1 21.5 52.0 15.8 21.1 16.2 22.0 17.5 7.4 8.6 21.4 12.9 37.5 20.0 104.9 21.7 1.9 16.8 120.3 26.3 19.7 22.7 15.7 17.5 196.9 16.5 6.6 20.4 11.2 60.7 31.6 29.6 20.3 9.6 12.5 30.3 123.1 15.2 8.2 32.5 24.6 12.7 13.7 34.3 12.4 94.6 19.8 15.3 68.0 112.1 94.4 31.8 21.7 14.3 94.9 53.4 10.4 9.1 15.5 50.7 6.6 26.4 27.2 28.2 15.3 17.5 27.4 13.1 88.3 4.6 18.7 62.5 RASA4 "CAPRI, GAPL, KIAA0538" ENSG00000105808 "RAS p21 protein activator 4" O43374 7 102573807-102616756 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 254.9;tongue: 88.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 73.9;Enteroendocrine cells: 71.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-138 MG: 48.9" HPA043010 Uncertain Approved "Vesicles,Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 56: Bipolar cells - Visual perception" Vesicles "Cell Junctions" "HPA043010: AB_2678267" "unprognostic (6.44e-2)" "unprognostic (3.64e-2)" "unprognostic (8.93e-3)" "unprognostic (1.69e-2)" "unprognostic (1.83e-1)" "unprognostic (1.17e-2)" "unprognostic (3.44e-1)" "unprognostic (7.45e-2)" "unprognostic (2.92e-1)" "unprognostic (2.29e-1)" "unprognostic (4.62e-3)" "unprognostic (4.19e-2)" "unprognostic (4.81e-2)" "unprognostic (8.87e-3)" "unprognostic (2.47e-2)" "unprognostic (3.34e-1)" "unprognostic (1.18e-2)" 38.9 17.5 22.9 10.8 18.8 6.0 31.2 22.7 23.0 37.4 3.6 29.8 10.9 37.7 4.7 10.8 28.4 6.3 14.5 22.5 22.8 29.2 2.6 22.1 13.8 21.5 25.9 25.2 12.3 12.8 24.2 13.0 17.3 23.4 4.0 13.3 12.9 18.0 254.9 17.3 21.6 7.5 17.2 16.8 16.1 5.4 22.7 4.8 17.3 88.6 7.1 26.0 29.0 16.3 1.1 1.5 14.1 2.6 1.8 5.8 0.6 16.3 7.6 4.3 4.9 6.1 3.1 9.9 11.9 24.0 0.3 12.7 0.6 0.1 1.7 1.7 2.4 3.2 4.1 1.0 2.1 2.0 4.4 6.4 1.4 1.4 0.4 18.7 2.7 6.5 5.9 17.0 1.4 4.0 8.6 7.1 1.0 6.6 7.3 17.5 2.9 16.5 0.4 5.0 12.7 25.3 2.3 2.3 1.9 7.5 1.1 5.7 3.0 48.9 22.3 4.9 4.1 28.9 18.5 7.7 4.3 4.5 5.9 0.4 7.9 0.2 1.3 8.6 3.0 3.2 2.4 1.8 10.9 2.9 2.5 1.5 1.8 1.4 1.1 9.2 3.3 3.8 22.9 18.8 22.7 23.0 22.5 22.8 21.5 25.9 17.3 17.2 22.7 16.3 26.8 12.8 10.9 15.0 8.3 3.8 4.5 1.3 0.6 73.9 2.0 3.0 1.1 2.8 5.2 3.7 16.7 0.2 7.2 5.9 13.7 1.1 0.4 3.3 13.0 24.9 71.8 5.7 5.6 0.7 0.2 5.0 3.1 2.9 1.3 13.6 3.3 1.4 6.0 28.6 6.6 11.8 0.0 11.6 22.8 0.3 8.4 13.3 1.8 4.7 14.2 9.4 6.2 5.5 1.4 1.7 2.8 7.9 4.0 2.9 19.9 8.4 6.2 11.7 13.1 21.3 10.0 3.4 3.3 1.3 3.4 0.4 6.4 5.6 2.9 4.1 RASA4B ENSG00000170667 "RAS p21 protein activator 4B" C9J798 7 102479976-102517777 "Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "skeletal muscle: 130.9" "Cell type enhanced" "Detected in some" "Astrocytes: 2.9;Bipolar cells: 3.3;Cardiomyocytes: 3.9;Gastric mucus-secreting cells: 5.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.2;intermediate monocyte: 2.0;myeloid DC: 3.3;plasmacytoid DC: 2.1" "Group enriched" "Detected in many" 6 "dendritic cells: 3.3;monocytes: 2.2" "Cell line enhanced" "Detected in many" "SH-SY5Y: 15.1;U-138 MG: 17.0;U-2 OS: 14.9" "Low region specificity" "Detected in all" HPA043010 Uncertain Approved "Vesicles,Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" Vesicles "Cell Junctions" "HPA043010: AB_2678267" "unprognostic (1.05e-2)" "unprognostic (1.34e-2)" "unprognostic (1.03e-2)" "unprognostic (1.96e-1)" "unprognostic (1.42e-2)" "unprognostic (1.40e-1)" "unprognostic (4.15e-2)" "unprognostic (1.55e-1)" "unprognostic (2.10e-1)" "unprognostic (6.79e-2)" "unprognostic (3.08e-3)" "unprognostic (2.31e-1)" "unprognostic (5.44e-4)" "unprognostic (1.18e-2)" "unprognostic (3.77e-2)" "unprognostic (4.37e-3)" "unprognostic (1.10e-1)" 14.0 5.8 6.5 4.2 6.1 2.2 10.8 6.3 7.9 13.3 3.0 11.9 6.4 16.5 1.3 2.8 9.7 3.7 4.7 6.2 8.0 6.4 0.8 6.0 4.7 7.8 8.3 9.6 2.4 5.2 5.8 4.9 6.7 8.1 1.8 5.3 4.5 7.6 130.9 5.5 7.8 3.8 6.6 5.9 4.9 2.1 7.6 1.9 3.8 19.2 2.8 9.5 9.5 7.5 0.2 1.4 3.7 0.5 1.3 2.9 0.2 6.8 4.4 2.2 3.6 0.5 1.1 3.4 7.3 8.6 0.7 9.1 0.0 0.0 1.1 0.5 1.6 0.5 2.7 0.8 1.2 0.3 0.5 2.9 0.8 0.1 0.2 10.4 0.9 1.7 0.9 9.8 0.7 3.0 2.9 1.9 0.3 1.7 1.9 2.8 1.5 4.6 0.1 0.9 3.1 15.1 1.0 0.5 0.5 3.0 1.0 2.0 2.0 17.0 14.9 1.8 0.6 3.5 2.9 2.4 2.3 0.9 2.8 0.0 2.2 0.0 0.3 2.0 0.2 0.1 0.3 0.1 3.3 0.2 0.3 0.4 0.3 0.0 0.4 2.1 0.3 1.2 6.5 6.1 6.3 7.9 6.2 8.0 7.8 8.3 6.7 6.6 7.6 7.5 0.6 0.0 0.6 2.9 1.1 0.4 0.2 0.0 1.2 3.3 0.1 0.3 3.9 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.9 0.1 0.0 0.1 0.3 1.8 2.4 0.4 0.5 0.2 0.0 0.3 5.6 0.1 0.0 0.5 0.0 0.0 0.3 0.0 0.8 1.3 0.0 0.6 0.9 0.0 0.3 1.0 0.0 1.0 0.6 0.6 0.0 1.5 0.0 0.1 0.0 0.0 2.5 0.2 1.3 0.3 0.1 0.6 0.0 0.5 0.8 0.3 0.0 0.3 1.1 0.1 1.6 0.3 0.0 0.2 RASGEF1B "FLJ31695, GPIG4" ENSG00000138670 "RasGEF domain family member 1B" Q0VAM2 4 81426393-82044244 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 118.7;granulocytes: 107.0;Langerhans cells: 282.6;Macrophages: 141.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 11.9;memory B-cell: 9.7;naive B-cell: 12.4;non-classical monocyte: 20.6;plasmacytoid DC: 28.0" "Group enriched" "Detected in all" 5 "B-cells: 12.4;dendritic cells: 28.0;monocytes: 20.6" "Cell line enhanced" "Detected in some" "CACO-2: 13.4;Daudi: 16.1;Karpas-707: 11.1;NTERA-2: 7.9;OE19: 9.2;SCLC-21H: 7.3;SuSa: 7.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044574 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Vesicles "HPA044574: AB_10794292" "unprognostic (3.24e-1)" "prognostic favorable (6.40e-4)" "unprognostic (1.32e-1)" "unprognostic (1.53e-1)" "unprognostic (1.19e-1)" "prognostic favorable (1.49e-5)" "unprognostic (4.42e-2)" "unprognostic (6.31e-2)" "unprognostic (4.43e-1)" "unprognostic (4.85e-2)" "unprognostic (1.13e-2)" "unprognostic (3.88e-2)" "prognostic favorable (4.21e-6)" "unprognostic (4.19e-3)" "unprognostic (1.44e-2)" "unprognostic (3.19e-2)" "unprognostic (6.04e-2)" 13.8 6.4 8.9 11.0 20.1 32.5 8.3 12.8 9.4 8.8 17.0 6.5 13.6 3.5 12.3 11.3 8.0 12.0 4.3 8.0 9.3 9.4 41.8 19.8 10.7 37.6 12.5 2.5 2.8 5.4 7.5 13.0 39.0 4.2 7.1 12.5 9.9 2.1 2.9 24.3 13.9 5.9 10.0 11.2 14.7 2.4 18.4 14.2 3.4 2.3 9.8 6.0 5.3 20.2 0.0 0.0 0.1 0.0 0.2 0.0 1.1 0.1 0.0 0.0 0.0 13.4 0.3 16.1 0.0 0.0 0.1 0.3 1.1 0.1 0.0 0.1 2.5 1.4 1.0 0.6 0.5 0.3 0.7 0.2 0.6 0.0 0.5 0.1 0.0 2.8 0.2 11.1 0.0 0.6 5.5 0.5 7.9 9.2 3.6 1.6 0.1 6.4 0.5 0.2 7.3 0.1 0.0 2.3 0.1 7.3 1.1 0.0 0.0 0.0 0.5 0.5 0.1 0.1 0.0 5.1 1.2 0.2 0.2 0.8 3.0 0.4 1.9 11.9 2.1 9.7 1.6 1.6 2.7 12.4 2.8 2.7 1.1 3.8 20.6 28.0 0.5 1.2 8.9 20.1 12.8 9.4 8.0 9.3 37.6 12.5 39.0 10.0 18.4 20.2 9.6 28.9 15.9 1.3 118.7 58.9 7.9 4.4 23.9 11.7 22.7 13.2 9.1 15.7 11.1 14.7 37.5 33.2 71.2 13.2 13.7 3.1 0.5 44.5 4.8 10.8 26.8 0.0 3.6 4.0 2.4 9.1 30.1 38.0 107.0 0.6 102.1 45.9 39.5 3.3 2.8 12.8 16.2 64.2 282.6 1.5 0.9 141.4 62.2 10.3 2.9 1.0 2.1 26.7 25.5 3.0 9.6 1.9 33.5 10.2 9.2 12.9 34.0 4.9 0.0 5.9 17.7 0.8 3.2 10.4 56.7 11.2 56.3 0.5 8.1 11.5 RASL10B "RRP17, VTS58635" ENSG00000270885 "RAS like family 10 member B" Q96S79 17 35731639-35743521 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.3;skeletal muscle: 31.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 13.8;Early spermatids: 10.4;Late spermatids: 34.6;Muller glia cells: 29.0" "Cancer enhanced" "Detected in many" "testis cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 24.3;HHSteC: 26.7;NTERA-2: 41.3;REH: 20.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046842, HPA057092" Enhanced Approved Vesicles NA NA "Cluster 47: Non-specific - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 5: Muller glia cells - Visual perception" Vesicles "HPA046842: AB_2679835, HPA057092: AB_2683332" "unprognostic (5.78e-2)" "unprognostic (2.15e-2)" "unprognostic (2.36e-2)" "prognostic unfavorable (6.38e-6)" "unprognostic (8.60e-2)" "unprognostic (1.24e-1)" "unprognostic (2.69e-2)" "unprognostic (4.98e-2)" "unprognostic (1.97e-2)" "unprognostic (7.13e-2)" "unprognostic (2.61e-2)" "unprognostic (3.18e-2)" "unprognostic (1.71e-6)" "unprognostic (2.41e-3)" "unprognostic (1.00e-1)" "unprognostic (1.32e-2)" "unprognostic (9.60e-3)" 15.4 1.7 25.9 0.1 32.3 0.0 11.3 8.7 25.6 3.9 7.6 1.9 0.7 2.8 0.6 0.4 3.9 0.7 19.3 26.5 18.1 3.0 2.1 1.2 0.1 16.5 19.2 3.7 4.9 5.2 6.7 2.8 18.0 2.9 0.1 9.0 9.1 14.7 31.5 0.8 1.2 0.7 13.2 0.3 1.8 3.0 17.5 0.4 1.7 0.9 0.1 1.4 2.3 12.9 0.0 0.3 6.3 0.0 1.1 0.6 1.8 1.2 0.8 4.3 3.6 8.1 0.0 0.0 0.7 0.2 0.0 0.0 24.3 0.0 1.5 0.0 8.0 0.0 4.1 9.3 26.7 0.0 0.0 19.5 1.5 1.5 0.0 3.4 0.0 13.2 5.5 0.0 0.3 0.5 11.6 0.0 41.3 0.0 0.0 20.8 11.1 18.5 0.0 0.0 18.3 17.8 1.2 0.4 1.7 17.8 2.3 1.2 0.0 2.0 14.5 0.1 0.5 0.0 0.0 5.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.9 32.3 8.7 25.6 26.5 18.1 16.5 19.2 18.0 13.2 17.5 12.9 0.3 0.0 0.5 0.3 0.0 0.1 0.5 0.0 0.0 3.9 2.7 1.4 13.8 4.3 0.0 1.8 2.1 0.0 0.0 0.0 0.0 1.3 10.4 1.0 0.7 0.7 0.0 0.0 2.6 0.0 0.0 1.9 0.0 1.4 0.0 2.8 0.0 6.7 0.2 6.7 4.9 0.2 0.0 0.6 0.0 34.6 2.1 0.1 0.0 1.0 0.0 29.0 0.0 0.5 0.5 0.3 0.0 3.0 0.0 0.6 0.4 0.1 0.0 1.2 0.0 1.5 2.3 4.8 0.9 0.0 0.0 0.3 0.1 7.0 0.4 0.2 RASSF10 ENSG00000189431 "Ras association domain family member 10" A6NK89 11 13009316-13012119 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 6.0;skin 1: 6.6" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 64.3;Distal tubular cells: 25.4;Gastric mucus-secreting cells: 17.9;Squamous epithelial cells: 60.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "A549: 8.9;CAPAN-2: 7.8;HaCaT: 12.6;HMC-1: 6.2;RPTEC TERT1: 11.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA040406 Approved Vesicles,Cytosol NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles Cytosol "HPA040406: AB_2732485" "unprognostic (6.71e-2)" "unprognostic (5.12e-2)" "unprognostic (5.06e-2)" "unprognostic (2.41e-3)" "unprognostic (6.25e-3)" "prognostic favorable (2.76e-4)" "unprognostic (3.43e-3)" "unprognostic (8.04e-2)" "unprognostic (5.89e-2)" "unprognostic (2.10e-1)" "unprognostic (1.56e-1)" "prognostic favorable (4.12e-5)" "unprognostic (4.45e-2)" "unprognostic (1.73e-1)" "unprognostic (2.88e-1)" "unprognostic (1.65e-2)" 0.3 0.0 0.4 0.0 0.8 0.0 1.3 0.2 0.5 0.6 0.3 0.4 1.2 0.1 0.1 6.0 3.0 0.3 0.3 0.2 0.3 3.4 0.0 1.2 0.0 0.7 1.0 0.0 0.0 2.1 0.1 0.0 0.7 0.6 0.4 0.0 4.6 0.2 0.7 6.6 0.5 0.0 1.0 0.0 3.6 0.5 0.1 0.5 0.1 0.2 0.5 1.1 1.5 0.5 0.4 8.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 7.8 0.0 0.5 0.0 0.3 12.6 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 2.2 0.0 1.3 0.0 0.0 11.9 1.3 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 0.2 0.5 0.2 0.3 0.7 1.0 0.7 1.0 0.1 0.5 2.0 0.0 5.1 0.7 0.1 0.0 6.3 0.0 64.3 0.0 5.8 8.0 0.9 0.0 2.5 1.8 0.0 0.2 0.0 0.9 25.4 0.6 0.0 6.0 1.1 1.4 2.4 0.0 0.0 0.2 0.0 0.2 17.9 11.1 1.3 0.0 3.9 0.0 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.3 0.3 0.5 0.0 1.9 0.0 0.9 0.0 0.0 0.0 11.5 1.2 0.0 0.0 1.9 0.0 4.5 7.3 0.0 0.0 0.5 0.3 0.0 0.8 60.0 0.0 0.0 0.2 0.0 5.5 3.5 RBMS3 ENSG00000144642 "RNA binding motif single stranded interacting protein 3" Q6XE24 3 28574791-30010391 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 331.1;Inhibitory neurons: 655.9;Microglial cells: 1013.7;Oligodendrocyte precursor cells: 229.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 5.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 9 "dendritic cells: 3.9" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 20.7;WM-115: 24.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034719 Uncertain Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA034719: AB_10670172" "unprognostic (8.39e-2)" "unprognostic (2.54e-2)" "unprognostic (1.02e-1)" "unprognostic (7.08e-2)" "unprognostic (2.29e-1)" "unprognostic (1.33e-1)" "unprognostic (3.13e-2)" "unprognostic (4.95e-2)" "unprognostic (1.08e-1)" "unprognostic (3.90e-2)" "unprognostic (1.90e-1)" "unprognostic (4.94e-2)" "prognostic unfavorable (1.85e-4)" "unprognostic (2.25e-3)" "unprognostic (3.81e-2)" "unprognostic (8.48e-2)" "unprognostic (3.24e-4)" 15.8 8.6 6.5 2.1 7.2 0.1 12.2 9.5 5.8 9.9 12.0 8.1 1.4 6.2 6.7 3.1 9.8 6.7 14.3 2.1 21.4 5.1 3.7 12.6 2.7 12.6 15.7 11.6 2.0 4.9 3.2 10.4 9.0 6.4 2.6 0.4 4.7 8.7 6.4 3.8 4.0 4.5 6.3 6.6 4.3 2.2 11.1 5.5 15.3 10.8 1.7 8.1 7.3 2.6 2.2 0.2 10.2 0.1 19.6 12.5 0.0 5.7 3.6 5.9 6.8 0.0 0.4 0.0 6.1 20.7 1.8 0.2 0.5 3.8 10.9 0.0 1.1 5.9 8.7 0.0 19.9 0.1 0.0 11.8 2.6 10.5 12.3 8.4 7.9 0.0 0.0 0.0 7.4 0.0 0.1 0.0 0.3 0.0 0.4 0.4 7.5 0.0 2.2 0.0 0.0 19.4 13.7 0.0 0.7 4.6 0.0 0.0 17.1 11.1 11.6 13.5 11.7 0.0 0.0 0.8 1.5 0.0 24.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 3.9 0.3 0.0 6.5 7.2 9.5 5.8 2.1 21.4 12.6 15.7 9.0 6.3 11.1 2.6 100.9 118.6 18.8 331.1 0.6 8.3 25.5 23.0 2.2 0.4 2.7 19.8 16.2 31.5 21.3 9.2 0.0 16.4 5.9 0.0 0.0 5.3 35.1 2.8 7.0 54.4 0.0 0.0 20.7 1.2 3.0 96.8 2.0 4.6 5.1 19.8 129.9 1.9 2.8 0.0 655.9 0.0 6.1 30.3 14.1 18.8 159.7 2.7 7.2 1013.7 0.6 0.0 0.0 229.2 8.9 0.4 0.0 110.6 0.1 24.3 0.0 2.9 10.5 0.0 111.7 154.6 73.5 1.2 1.5 2.4 7.2 9.6 2.9 22.4 0.0 4.7 RBP5 CRBPIII ENSG00000139194 "Retinol binding protein 5" P82980 12 7115736-7128889 "Plasma proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 443.5;liver: 324.2" "Cell type enriched" "Detected in many" 8 "Proximal tubular cells: 3197.2" "Group enriched" "Detected in all" 8 "liver cancer: 70.1;renal cancer: 126.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 6.0;Hep G2: 13.4;K-562: 26.3" HPA038723 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus" Vesicles "HPA038723: AB_2676175" "unprognostic (5.70e-3)" "unprognostic (7.34e-2)" "unprognostic (2.72e-2)" "unprognostic (1.53e-2)" "unprognostic (1.87e-2)" "unprognostic (1.39e-3)" "unprognostic (2.49e-2)" "prognostic favorable (8.37e-4)" "unprognostic (1.04e-1)" "unprognostic (2.65e-1)" "unprognostic (1.13e-2)" "unprognostic (1.13e-1)" "unprognostic (1.04e-1)" "unprognostic (1.83e-2)" "unprognostic (3.33e-2)" "unprognostic (4.22e-1)" "prognostic favorable (3.68e-4)" 6.4 11.7 0.0 15.0 0.1 1.6 5.1 0.3 0.3 11.2 0.2 8.5 4.6 8.6 3.2 3.8 8.1 5.9 1.4 0.0 0.0 443.5 324.2 3.8 31.2 0.5 0.3 4.9 5.2 1.3 6.2 0.3 0.3 10.0 4.9 0.8 3.7 5.0 0.7 2.4 20.6 5.4 0.0 97.1 5.2 2.2 0.2 14.2 7.9 0.0 21.4 7.4 4.6 0.0 0.9 1.3 0.0 0.3 0.0 0.0 0.2 1.1 0.0 0.0 0.2 1.1 1.2 1.0 0.3 0.0 0.1 1.2 0.1 0.0 0.0 1.6 0.0 6.0 3.9 13.4 0.0 0.2 0.9 0.2 0.0 0.0 0.0 2.4 0.0 0.6 26.3 0.7 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.2 0.0 0.1 0.1 1.2 0.0 0.2 1.4 0.9 0.0 0.6 0.5 0.7 0.7 0.6 0.5 2.8 0.4 0.3 0.1 0.0 0.3 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.3 0.3 0.0 0.0 0.5 0.3 0.3 0.0 0.2 0.0 4.9 0.0 0.6 0.7 15.2 1.5 0.5 0.1 0.0 1.2 1.3 1.3 0.1 5.7 0.1 80.9 0.0 0.1 0.3 0.1 352.1 0.2 4.1 0.3 1.7 28.8 0.0 0.0 2.1 0.4 0.0 8.2 0.0 0.5 0.0 0.2 8.9 361.1 0.1 5.0 1.1 0.0 0.0 8.1 2.6 6.7 2.5 16.6 0.0 1.9 0.0 1.4 0.0 0.5 0.1 0.2 0.0 0.4 0.1 0.5 0.0 3197.2 0.9 1.7 0.0 0.1 4.3 0.7 0.4 0.2 2.3 0.0 7.3 2.4 0.1 0.3 RBSN ZFYVE20 ENSG00000131381 "Rabenosyn, RAB effector" Q9H1K0 3 15070073-15099163 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044878 Approved Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 59: Non-specific - Transcription" Vesicles "HPA044878: AB_10967610" "unprognostic (6.76e-2)" "unprognostic (2.18e-1)" "unprognostic (3.00e-3)" "unprognostic (1.00e-1)" "unprognostic (8.06e-2)" "unprognostic (3.79e-3)" "unprognostic (1.09e-3)" "unprognostic (1.72e-2)" "unprognostic (3.57e-1)" "unprognostic (1.90e-2)" "unprognostic (2.00e-2)" "unprognostic (9.34e-2)" "unprognostic (2.38e-3)" "unprognostic (4.45e-2)" "unprognostic (1.41e-1)" "unprognostic (2.72e-1)" "unprognostic (1.78e-1)" 9.0 7.0 12.5 6.7 12.5 18.2 7.7 10.2 13.0 9.1 1.1 10.7 4.7 9.3 7.1 8.9 8.7 5.4 9.8 13.4 11.4 5.4 8.4 8.4 6.6 12.1 12.5 12.7 5.9 9.7 6.1 7.9 11.1 7.4 5.3 13.6 5.9 9.0 13.1 10.2 7.1 9.0 12.8 7.7 7.8 6.6 13.0 5.5 11.2 9.9 6.1 9.1 7.5 11.8 11.2 16.0 12.8 16.6 13.8 10.2 33.9 12.0 11.5 14.1 12.7 9.7 6.5 7.8 6.8 15.9 8.2 7.0 16.5 14.5 12.4 9.9 14.6 8.9 19.7 8.0 9.5 9.0 9.4 11.1 16.1 18.1 12.0 8.3 11.6 8.7 13.5 8.9 10.8 14.7 4.9 4.5 11.0 7.1 12.7 6.4 14.6 8.6 7.3 12.6 3.4 12.0 14.7 8.9 10.7 9.4 22.8 6.5 14.2 12.7 13.3 12.5 17.1 7.9 12.6 9.2 12.2 10.0 12.2 8.1 4.6 11.1 4.4 6.4 3.9 4.4 6.1 5.5 3.8 7.4 7.7 5.2 11.7 3.1 5.6 3.6 4.3 2.7 12.5 12.5 10.2 13.0 13.4 11.4 12.1 12.5 11.1 12.8 13.0 11.8 10.4 16.0 19.0 19.6 9.2 0.0 6.7 0.0 6.8 21.6 7.6 7.0 20.4 8.6 9.9 3.7 22.9 10.4 8.4 6.0 5.9 8.4 17.4 6.4 11.1 12.4 1.2 9.5 21.8 9.6 9.6 14.6 10.2 8.8 10.1 16.4 14.6 14.0 10.7 21.9 23.9 6.9 0.0 15.8 0.0 18.0 19.0 12.1 0.0 8.4 10.5 15.5 7.2 16.1 25.2 9.6 5.1 14.7 12.1 12.6 8.1 6.9 8.0 23.1 6.6 17.5 10.4 12.4 14.0 11.0 0.0 12.9 9.9 10.6 5.4 10.0 RC3H2 "FLJ20301, FLJ20713, MNAB, RNF164" ENSG00000056586 "Ring finger and CCCH-type domains 2" Q9HBD1 9 122844556-122905359 "Enzymes, Predicted intracellular proteins, Transcription factors" "Ubl conjugation pathway" "Repressor, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042863, HPA062144" Approved Enhanced Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 44: Endometrium - Transcription" Vesicles "HPA042863: AB_2678204, HPA062144: AB_2732677" "unprognostic (6.05e-2)" "unprognostic (7.87e-2)" "unprognostic (7.24e-2)" "unprognostic (1.66e-1)" "unprognostic (4.08e-3)" "unprognostic (2.37e-1)" "unprognostic (2.43e-2)" "unprognostic (3.92e-2)" "unprognostic (1.99e-1)" "unprognostic (1.57e-1)" "unprognostic (1.80e-1)" "unprognostic (1.21e-1)" "prognostic favorable (5.50e-4)" "unprognostic (1.36e-1)" "unprognostic (1.68e-1)" "unprognostic (2.16e-1)" "unprognostic (1.26e-1)" 11.9 8.9 8.8 12.1 10.8 32.5 10.4 14.0 10.0 13.5 4.4 10.4 9.9 11.9 8.1 13.0 9.7 11.0 13.8 10.9 7.9 12.7 13.4 11.5 18.5 7.1 7.4 11.2 6.8 15.8 9.6 14.6 7.6 9.7 11.2 16.0 9.0 9.1 11.8 10.0 9.4 13.9 7.1 14.1 11.8 11.6 8.0 18.8 12.9 15.3 17.2 14.4 9.0 10.5 17.3 26.2 33.5 18.2 17.4 19.8 17.8 22.0 24.4 25.2 21.8 31.2 18.8 28.8 16.7 29.8 30.1 40.9 35.4 25.1 27.7 13.4 13.5 16.4 44.4 21.3 23.1 19.9 26.5 19.9 25.5 24.3 34.6 22.0 35.6 25.4 24.1 21.6 32.9 23.9 20.2 14.7 17.7 24.9 21.8 19.7 54.8 19.4 25.8 13.9 38.3 25.8 39.2 24.9 21.2 22.8 29.2 17.2 33.9 20.5 17.3 27.7 39.8 14.0 25.4 32.1 22.3 18.2 23.1 10.0 4.6 6.0 6.1 7.3 5.1 4.3 4.8 6.0 4.1 5.8 4.5 4.5 8.0 4.0 6.7 6.5 5.1 2.8 8.8 10.8 14.0 10.0 10.9 7.9 7.1 7.4 7.6 7.1 8.0 10.5 33.8 41.7 32.8 20.9 27.7 11.0 13.6 20.0 20.5 19.2 15.6 10.5 34.8 12.8 17.3 9.2 37.5 15.7 26.6 18.9 3.9 12.0 5.9 27.6 30.9 28.3 23.3 22.7 38.4 11.4 15.2 18.4 23.9 40.1 17.1 21.9 29.6 19.5 9.6 28.6 35.1 19.8 12.2 27.4 19.4 9.5 13.4 21.4 14.2 30.9 26.1 16.9 24.7 35.2 39.3 23.5 9.0 18.0 22.5 24.3 14.8 12.0 17.7 20.2 19.7 16.3 24.1 30.7 17.9 23.3 14.8 23.0 28.8 15.4 14.7 27.3 RCHY1 "ARNIP, CHIMP, DKFZp586C1620, PIRH2, PRO1996, RNF199, ZCHY, ZNF363" ENSG00000163743 "Ring finger and CHY zinc finger domain containing 1" Q96PM5 4 75479037-75514764 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030338, HPA030339" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Nucleoplasm, Vesicles" "HPA030338: , HPA030339: AB_10603232" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "prognostic favorable (9.09e-4)" "unprognostic (1.90e-1)" "unprognostic (3.45e-3)" "unprognostic (1.19e-2)" "unprognostic (7.87e-3)" "unprognostic (5.82e-2)" "unprognostic (1.96e-1)" "unprognostic (1.98e-1)" "unprognostic (7.45e-3)" "unprognostic (4.60e-2)" "prognostic favorable (3.62e-5)" "unprognostic (1.69e-1)" "unprognostic (2.07e-1)" "unprognostic (1.83e-1)" "prognostic favorable (7.89e-5)" 8.6 7.0 9.5 7.9 10.2 17.0 16.8 12.6 13.0 9.0 7.7 12.1 8.7 9.6 6.9 7.2 11.9 6.8 16.8 9.4 10.6 16.2 12.3 10.0 9.5 8.9 10.4 14.5 8.3 12.6 5.8 10.0 9.9 10.9 13.2 14.8 12.9 10.1 16.5 5.6 8.6 11.6 9.9 11.5 8.9 13.6 10.7 12.7 18.9 23.6 12.6 7.6 4.7 10.7 9.8 5.0 14.6 13.8 15.1 13.1 8.4 6.5 15.1 13.2 15.4 13.8 11.9 16.2 12.0 9.4 13.1 5.8 37.6 11.5 19.9 13.4 12.3 21.2 9.2 17.9 13.0 28.9 11.2 12.2 14.1 15.2 14.2 15.9 27.0 20.8 19.9 16.2 30.9 15.8 26.7 11.5 24.5 26.9 8.7 14.2 34.4 13.9 20.4 16.7 22.6 12.4 10.7 24.8 28.2 15.9 14.0 12.9 10.8 8.6 8.5 7.8 11.1 17.0 13.0 22.8 10.5 20.2 14.0 27.5 9.2 9.7 4.3 5.7 7.6 4.6 5.4 5.2 8.0 2.1 3.9 5.5 4.0 5.5 5.6 4.1 5.7 4.7 9.5 10.2 12.6 13.0 9.4 10.6 8.9 10.4 9.9 9.9 10.7 10.7 22.2 19.2 10.3 28.4 25.4 40.7 32.3 47.1 39.3 35.0 38.5 25.9 56.8 24.3 23.5 23.9 20.9 31.6 31.2 21.9 68.4 30.3 37.3 11.9 17.1 22.3 13.8 21.8 31.2 22.5 23.2 24.6 21.9 17.3 5.1 23.8 25.4 23.0 19.0 23.5 32.3 23.4 38.7 37.5 26.8 59.8 22.4 27.4 28.4 22.5 23.9 32.0 24.7 31.7 41.0 26.5 22.6 25.2 19.7 36.6 24.6 69.4 13.5 21.7 32.9 20.9 27.3 72.8 41.7 28.1 31.0 33.8 32.9 35.2 27.6 26.3 RCN3 RLP49 ENSG00000142552 "Reticulocalbin 3" Q96D15 19 49528003-49546962 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 54.7;Fibroblasts: 105.1;Leydig cells: 38.2;Peritubular cells: 44.8;Smooth muscle cells: 66.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 6.8" "Group enriched" "Detected in many" 9 "granulocytes: 2.5;NK-cells: 1.8;T-cells: 6.8" "Cell line enhanced" "Detected in many" "AN3-CA: 166.6;ASC diff: 283.3;ASC TERT1: 175.4;BJ: 353.8;BJ hTERT+ SV40 Large T+ RasG12V: 179.6;fHDF/TERT166: 304.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043134, HPA050402" Uncertain Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" No No 1600000 "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Endoplasmic reticulum" Vesicles "HPA043134: AB_2678332, HPA050402: AB_2681114" "unprognostic (7.10e-2)" "unprognostic (1.19e-1)" "unprognostic (3.77e-3)" "unprognostic (8.87e-2)" "unprognostic (3.36e-3)" "unprognostic (1.27e-1)" "unprognostic (2.30e-3)" "unprognostic (1.16e-1)" "unprognostic (7.47e-2)" "unprognostic (9.75e-2)" "unprognostic (2.85e-1)" "unprognostic (3.86e-2)" "prognostic unfavorable (5.80e-12)" "unprognostic (5.26e-2)" "unprognostic (3.90e-2)" "unprognostic (1.56e-2)" "unprognostic (4.20e-3)" 67.9 35.3 15.8 33.6 17.2 6.8 48.2 15.5 24.1 78.8 23.5 43.5 39.9 47.4 4.4 11.4 41.4 25.2 56.7 16.0 19.1 41.2 62.3 40.8 8.7 17.4 17.0 50.0 16.4 3.9 20.7 31.1 19.0 32.4 11.4 1.4 19.1 12.1 11.7 25.3 43.2 25.7 16.8 65.9 23.4 17.2 24.5 4.0 26.4 7.5 4.1 43.2 46.3 18.8 3.2 4.3 2.7 166.6 283.3 175.4 1.9 353.8 86.5 122.0 179.6 4.2 1.3 1.3 19.5 304.0 1.3 0.3 6.8 0.5 49.2 0.1 2.5 19.5 1.5 9.1 105.7 0.1 43.0 119.5 0.2 93.2 0.4 3.2 43.8 2.3 8.7 1.0 87.8 2.9 0.1 2.0 1.4 8.8 24.5 0.5 3.9 4.0 1.4 0.0 1.7 10.5 0.3 1.1 0.3 2.8 1.3 11.5 121.4 1.7 52.4 135.3 0.1 14.9 44.5 2.6 7.9 9.6 13.4 0.0 0.2 1.6 0.7 0.0 0.7 0.4 1.7 0.6 0.4 0.2 6.8 2.3 2.5 1.8 0.3 0.2 1.6 1.1 15.8 17.2 15.5 24.1 16.0 19.1 17.4 17.0 19.0 16.8 24.5 18.8 12.0 0.0 6.1 4.6 2.8 18.6 0.6 2.9 3.4 0.8 1.7 3.3 2.1 1.5 0.8 1.8 0.0 2.5 1.4 10.5 1.9 1.6 2.2 1.5 54.7 10.6 1.2 0.0 1.0 0.5 5.0 105.1 6.6 1.6 1.3 7.0 27.1 3.7 22.6 1.7 1.1 7.6 0.0 11.4 23.2 3.0 38.2 11.9 10.6 10.3 3.1 0.6 0.0 1.5 0.8 1.5 7.9 44.8 4.8 0.9 13.1 0.6 0.9 0.8 13.1 37.5 66.5 6.5 6.8 2.8 13.9 6.2 2.2 17.2 8.0 0.4 RCOR2 ENSG00000167771 "REST corepressor 2" Q8IZ40 11 63911230-63917164 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 20.7;Excitatory neurons: 5.9;Extravillous trophoblasts: 4.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 35.7;NTERA-2: 47.0;SCLC-21H: 72.6;SH-SY5Y: 48.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021638 Uncertain Approved Nucleoplasm,Vesicles,Midbody Yes NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "Vesicles, Midbody" "HPA021638: AB_10960885" "unprognostic (1.96e-2)" "unprognostic (1.15e-1)" "unprognostic (4.10e-2)" "unprognostic (1.98e-3)" "unprognostic (3.10e-2)" "unprognostic (5.86e-2)" "unprognostic (2.33e-4)" "unprognostic (8.64e-2)" "unprognostic (1.46e-1)" "unprognostic (4.80e-2)" "unprognostic (1.67e-1)" "unprognostic (1.72e-3)" "unprognostic (2.62e-1)" "unprognostic (1.75e-1)" "unprognostic (3.51e-1)" "unprognostic (9.93e-2)" "unprognostic (6.06e-3)" 0.3 0.5 1.8 0.2 3.2 0.0 0.4 1.3 3.7 1.4 0.1 1.1 0.8 2.7 1.0 0.4 1.5 0.4 2.8 2.5 1.1 0.6 0.1 0.3 0.0 1.2 1.0 1.2 0.5 1.4 3.5 0.7 0.8 0.9 0.6 3.4 0.9 0.6 1.5 0.3 0.6 1.0 1.1 0.1 0.7 3.2 1.0 0.9 0.2 0.7 0.0 1.2 0.6 2.4 0.0 1.0 35.7 2.5 0.5 2.9 10.9 0.2 0.6 0.5 1.2 1.4 0.3 0.3 0.4 0.8 0.7 0.4 15.8 0.0 0.3 0.6 2.0 0.5 0.3 11.9 5.9 0.0 0.3 3.5 0.0 0.6 0.0 0.0 0.3 4.8 2.0 0.0 0.0 3.3 3.4 13.2 47.0 4.8 0.1 12.4 2.1 1.0 0.1 0.1 72.6 48.7 0.3 3.2 1.8 8.7 2.7 4.5 0.3 0.1 2.3 0.1 0.1 0.3 0.1 0.4 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 3.2 1.3 3.7 2.5 1.1 1.2 1.0 0.8 1.1 1.0 2.4 0.6 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 20.7 0.6 0.4 2.2 0.0 0.1 0.0 0.0 0.5 0.0 1.0 0.0 0.1 0.1 0.3 3.3 0.6 1.2 0.0 5.9 0.2 4.4 1.1 0.0 0.6 0.0 1.2 0.0 0.0 0.2 3.3 1.5 1.2 2.0 0.0 0.0 0.1 1.5 0.1 0.0 0.0 0.0 2.1 1.0 1.0 1.5 0.2 0.2 0.4 0.0 0.0 0.3 0.1 0.2 2.2 0.0 0.3 0.7 0.7 2.9 0.0 0.3 0.8 0.1 1.2 0.8 0.1 RDH5 "HSD17B9, RDH1, SDR9C5" ENSG00000135437 "Retinol dehydrogenase 5" Q92781 12 55720367-55724705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sensory transduction, Steroid metabolism, Vision" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 94.5;liver: 58.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 62.6;Proximal enterocytes: 49.9;Rod photoreceptor cells: 62.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 28.5;ASC TERT1: 24.3;hTEC/SVTERT24-B: 15.3;hTERT-RPE1: 24.5;LHCN-M2: 15.4;U-87 MG: 26.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063345 Uncertain Vesicles "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" Vesicles "HPA063345: AB_2684992" "unprognostic (1.04e-2)" "unprognostic (6.45e-2)" "unprognostic (1.80e-1)" "unprognostic (2.67e-1)" "unprognostic (3.66e-2)" "unprognostic (1.48e-2)" "unprognostic (1.88e-2)" "unprognostic (1.54e-1)" "unprognostic (5.35e-2)" "unprognostic (4.04e-2)" "unprognostic (4.05e-1)" "unprognostic (1.26e-3)" "unprognostic (7.63e-2)" "unprognostic (8.79e-2)" "unprognostic (3.46e-2)" "unprognostic (2.12e-3)" "unprognostic (3.27e-2)" 94.5 1.8 2.2 4.1 2.5 1.0 34.2 2.2 2.6 2.5 3.5 13.6 18.5 4.2 7.8 3.1 4.6 4.2 9.2 2.0 2.2 9.0 58.9 1.9 1.8 2.7 2.5 2.1 3.5 0.3 1.7 0.6 2.4 4.4 4.4 3.2 3.3 2.2 6.1 2.7 15.5 19.5 2.5 2.2 5.9 2.4 2.8 0.9 2.7 7.6 0.7 5.5 2.2 3.4 0.7 1.4 0.8 0.5 28.5 24.3 0.6 3.8 4.2 0.7 1.4 0.5 7.9 1.0 0.7 2.1 0.2 0.3 0.3 0.1 0.6 1.0 1.3 0.1 2.0 2.1 0.8 0.1 0.3 10.5 1.0 15.3 0.1 24.5 0.3 0.5 0.2 1.3 15.4 0.7 0.4 0.2 0.3 3.7 2.3 0.6 0.4 0.5 0.2 0.8 0.2 1.1 0.2 0.5 3.4 0.2 0.7 0.6 0.5 1.5 1.5 1.1 0.9 1.1 0.5 0.2 26.7 0.4 0.3 0.0 0.1 0.5 0.0 0.1 0.0 0.1 0.2 0.5 0.2 0.0 0.2 0.0 0.2 0.3 0.2 0.5 0.0 0.0 2.2 2.5 2.2 2.6 2.0 2.2 2.7 2.5 2.4 2.5 2.8 3.4 2.5 9.6 2.2 0.0 4.6 1.9 4.5 3.9 0.6 24.3 2.7 5.0 3.9 10.0 2.4 1.8 62.6 2.2 5.3 23.5 1.9 2.1 0.8 1.8 2.9 3.7 11.5 0.0 0.0 2.6 1.2 3.9 11.2 1.5 0.0 4.9 3.6 18.4 0.6 16.8 0.0 10.3 0.0 4.5 7.9 2.3 13.4 2.3 5.4 0.0 4.7 8.2 12.3 0.0 0.0 3.6 18.6 6.8 0.7 3.2 49.9 13.0 4.7 62.9 13.1 14.0 9.3 3.9 6.4 0.8 1.7 1.5 4.8 5.3 15.9 3.1 RELL2 "C5orf16, FLJ90583" ENSG00000164620 "RELT like 2" Q8NC24 5 141636950-141641064 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.2;parathyroid gland: 16.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 28.5;Horizontal cells: 65.6;Inhibitory neurons: 28.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 31.7;JURKAT: 32.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077928 Uncertain Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 62: Horizontal cells - Visual perception" Vesicles "HPA077928: " "unprognostic (3.27e-2)" "unprognostic (8.46e-2)" "unprognostic (2.12e-1)" "unprognostic (4.95e-3)" "unprognostic (1.91e-3)" "unprognostic (7.12e-2)" "unprognostic (1.11e-2)" "unprognostic (1.05e-1)" "unprognostic (3.69e-2)" "unprognostic (2.12e-2)" "unprognostic (6.76e-4)" "unprognostic (4.17e-2)" "unprognostic (1.85e-2)" "unprognostic (7.85e-2)" "unprognostic (8.74e-3)" "unprognostic (4.31e-2)" "unprognostic (6.58e-2)" 1.0 5.9 14.4 1.3 12.8 1.0 1.3 18.8 38.2 1.6 5.4 1.4 1.5 2.1 0.6 3.5 0.8 1.0 1.0 13.4 19.3 3.7 1.9 3.3 2.5 34.1 18.9 0.8 1.4 16.1 15.7 2.3 31.4 2.1 0.7 3.6 2.7 0.5 0.3 2.7 2.8 0.8 10.6 5.8 1.1 6.0 28.5 4.8 2.8 0.0 2.5 1.5 1.8 17.6 1.6 4.3 4.3 7.7 3.2 1.1 2.0 3.6 6.7 11.4 16.9 16.6 1.6 0.2 1.7 5.4 24.9 7.0 4.1 15.1 2.9 4.7 2.5 10.3 10.0 7.8 5.2 3.5 31.7 2.2 9.3 10.6 7.7 2.5 3.1 32.9 3.4 5.3 2.6 2.1 5.8 1.6 4.8 5.7 2.3 0.4 1.0 6.7 3.6 3.9 7.0 7.6 3.3 15.1 2.7 0.6 5.4 8.4 3.8 8.8 4.1 7.1 6.6 3.2 9.0 23.4 4.5 14.5 5.6 0.0 0.8 0.0 1.6 2.0 0.6 1.4 1.7 1.6 1.3 0.8 1.5 0.8 0.6 0.0 1.4 4.5 3.2 1.2 14.4 12.8 18.8 38.2 13.4 19.3 34.1 18.9 31.4 10.6 28.5 17.6 1.1 0.0 0.6 4.2 6.0 4.6 1.5 2.6 2.8 10.5 2.3 2.4 0.3 1.5 2.0 1.8 12.5 0.2 10.0 4.2 1.9 3.3 1.8 0.3 0.8 2.0 1.2 0.0 28.5 2.5 4.1 0.8 0.5 0.2 0.0 0.4 0.4 0.2 4.2 65.6 28.8 2.4 4.1 4.4 3.5 4.7 0.6 5.1 7.2 4.7 2.3 6.6 5.2 2.5 2.8 2.1 5.0 1.5 1.7 2.7 1.2 5.6 1.9 8.6 0.0 0.3 1.3 17.8 7.5 3.6 4.3 6.2 5.5 0.9 0.9 2.2 RELN "PRO1598, RL" ENSG00000189056 Reelin P78509 7 103471381-103989658 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Developmental protein, Hydrolase, Protease, Serine protease" "Disease variant, Epilepsy, Lissencephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 64.4" "Group enriched" "Detected in some" 8 "Hepatic stellate cells: 128.5;Inhibitory neurons: 372.4" "Cancer enhanced" "Detected in many" "liver cancer: 5.7" "Region enriched" "Detected in many" 10 "cerebellum: 64.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Hep G2: 16.2;PC-3: 8.6;SCLC-21H: 11.1;SH-SY5Y: 13.7;TIME: 33.0" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 110.0" HPA077891 Approved "Golgi apparatus,Vesicles" "Secreted in brain" NA NA 30000000 "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Golgi apparatus" Vesicles "HPA077891: " "unprognostic (1.42e-1)" "unprognostic (2.93e-3)" "unprognostic (4.31e-2)" "unprognostic (1.29e-4)" "unprognostic (1.30e-1)" "unprognostic (6.95e-2)" "unprognostic (1.85e-1)" "unprognostic (8.35e-2)" "unprognostic (1.54e-1)" "unprognostic (1.48e-2)" "unprognostic (3.31e-3)" "unprognostic (3.86e-1)" "unprognostic (2.02e-2)" "unprognostic (1.43e-2)" "unprognostic (3.03e-1)" "unprognostic (1.35e-1)" "unprognostic (3.06e-2)" 1.3 1.8 2.0 0.6 1.8 0.0 2.7 64.4 3.8 1.5 0.6 0.8 0.2 0.4 0.1 0.8 2.8 0.7 1.7 3.3 6.4 0.4 13.4 0.5 0.4 2.6 4.2 0.4 0.1 0.0 0.5 0.0 6.3 0.6 0.9 2.9 0.8 0.9 0.2 0.6 0.9 0.7 3.9 0.3 0.5 0.7 0.5 0.0 1.7 1.1 0.2 0.7 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 2.1 0.0 0.1 0.0 0.0 4.3 0.0 16.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 1.9 0.0 0.0 0.0 11.1 13.7 0.0 0.0 0.0 0.0 0.0 0.0 33.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.8 64.4 3.8 3.3 6.4 2.6 4.2 6.3 3.9 0.5 0.5 1.0 0.0 0.0 9.1 0.5 0.6 0.0 0.0 0.6 30.2 0.5 0.4 5.1 4.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 13.6 0.1 0.0 8.3 0.0 7.0 2.6 1.2 0.1 7.5 0.0 0.1 0.0 0.0 128.5 3.3 0.2 0.0 372.4 0.0 0.0 5.3 2.2 6.1 0.0 0.1 0.0 2.8 0.0 0.2 0.0 3.0 10.3 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.8 0.7 0.1 0.8 0.0 0.6 0.3 0.4 0.0 0.0 0.0 REPS1 ENSG00000135597 "RALBP1 associated Eps domain containing 1" Q96D71 6 138903493-138988261 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 207.3;Excitatory neurons: 114.3;Inhibitory neurons: 138.1;Oligodendrocyte precursor cells: 99.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029961, HPA029962" Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane, Cytosol" "HPA029961: AB_10603233, HPA029962: AB_2673269" "unprognostic (1.72e-3)" "unprognostic (9.61e-2)" "unprognostic (5.82e-3)" "unprognostic (2.77e-2)" "unprognostic (6.30e-3)" "unprognostic (1.90e-1)" "prognostic unfavorable (9.47e-4)" "unprognostic (3.79e-1)" "unprognostic (2.49e-1)" "unprognostic (9.71e-3)" "unprognostic (4.29e-3)" "unprognostic (4.42e-2)" "unprognostic (2.69e-1)" "unprognostic (1.51e-1)" "unprognostic (1.27e-1)" "unprognostic (3.83e-2)" "unprognostic (2.69e-2)" 13.5 11.9 24.7 14.9 25.4 23.2 23.6 27.7 36.8 19.2 14.8 17.4 15.4 21.9 40.2 28.0 18.4 14.0 23.9 27.4 24.0 17.4 31.3 15.2 19.4 25.2 23.9 21.1 18.8 41.0 31.7 17.2 21.3 15.9 17.3 38.8 26.1 16.2 17.5 30.0 16.4 19.5 21.5 22.1 18.1 35.6 25.9 36.0 17.8 12.6 22.2 19.5 20.1 25.3 29.3 22.6 42.3 53.1 23.4 41.6 46.2 27.8 30.7 31.9 38.2 54.1 24.8 35.2 22.9 38.9 38.0 33.6 48.7 42.0 42.1 37.6 41.9 29.6 12.9 32.9 35.3 94.6 45.9 34.1 33.7 58.6 70.3 30.2 33.5 51.2 40.2 35.1 41.4 49.4 53.9 51.3 40.4 37.4 21.3 62.4 26.0 20.0 26.5 43.6 37.7 37.2 25.7 38.7 38.0 62.0 18.6 64.4 32.9 17.8 29.6 48.5 38.8 34.4 33.7 49.2 21.1 38.3 26.4 5.9 1.3 1.9 2.2 4.0 3.8 3.0 2.9 3.2 1.9 1.6 2.9 3.6 0.7 2.9 4.5 3.5 3.3 1.2 24.7 25.4 27.7 36.8 27.4 24.0 25.2 23.9 21.3 21.5 25.9 25.3 11.8 19.2 7.4 207.3 18.0 13.4 11.7 7.9 22.2 12.6 13.7 9.5 28.4 10.0 12.2 5.5 16.7 25.6 18.9 11.9 7.9 7.8 13.7 17.5 9.7 10.3 6.0 5.0 114.3 7.1 28.3 11.5 16.3 23.3 15.9 14.4 15.7 43.8 13.3 13.5 138.1 12.8 6.1 24.0 10.3 7.7 7.2 17.2 5.4 47.8 10.5 36.8 15.5 99.5 71.2 8.9 14.7 8.6 23.9 11.2 13.5 8.6 16.5 14.4 19.7 16.8 10.9 41.7 33.8 26.4 14.9 28.6 18.7 7.6 15.2 18.1 REX1BD "C19orf60, FLJ20850, FLJ30108, FLJ34606, FLJ37391" ENSG00000006015 "Required for excision 1-B domain containing" Q96EN9 19 18588685-18592337 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 154.6;Extravillous trophoblasts: 147.6;Hofbauer cells: 258.2;Proximal tubular cells: 222.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 64.5;PC-3: 98.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043414 Approved Approved Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA043414: AB_10797141" "unprognostic (1.12e-1)" "unprognostic (1.96e-1)" "unprognostic (1.15e-1)" "unprognostic (6.78e-3)" "unprognostic (1.22e-1)" "unprognostic (4.87e-3)" "unprognostic (2.52e-2)" "unprognostic (1.45e-1)" "unprognostic (4.60e-1)" "unprognostic (3.10e-1)" "unprognostic (5.50e-3)" "unprognostic (3.24e-2)" "unprognostic (3.19e-2)" "unprognostic (4.02e-2)" "unprognostic (9.27e-2)" "unprognostic (1.48e-1)" "prognostic favorable (8.47e-4)" 42.9 40.7 25.5 5.0 23.8 8.1 41.3 21.7 45.2 40.3 11.9 39.3 6.7 39.6 0.5 31.6 34.0 1.9 76.5 24.3 25.3 48.3 63.5 33.9 2.4 25.9 22.5 38.9 52.8 4.3 32.3 3.6 24.2 40.0 1.0 0.6 33.8 6.1 106.4 42.8 33.8 2.4 22.7 47.6 39.0 10.8 26.3 3.9 27.6 9.2 2.2 39.1 38.1 24.9 18.2 20.6 2.0 3.8 2.6 3.1 64.5 19.2 3.0 4.2 4.9 3.8 21.8 18.7 58.4 3.2 1.7 12.9 0.9 4.6 1.1 19.5 47.1 12.1 7.5 9.8 3.7 11.7 28.7 5.2 5.2 2.2 1.1 1.8 5.4 8.4 16.8 6.8 2.2 26.3 19.9 18.6 29.3 9.5 98.5 21.4 5.5 47.2 7.4 15.0 9.5 34.6 9.1 10.8 25.0 0.8 5.2 7.5 18.5 2.4 18.8 25.5 10.7 52.3 17.3 12.7 18.0 18.9 9.7 100.5 150.9 152.5 148.6 140.1 153.1 126.4 151.4 134.5 146.9 91.6 135.4 128.6 89.4 101.3 132.4 125.8 134.6 143.6 25.5 23.8 21.7 45.2 24.3 25.3 25.9 22.5 24.2 22.7 26.3 24.9 126.2 28.9 41.2 0.0 38.7 0.0 0.0 0.0 0.0 0.0 100.0 136.5 0.0 0.0 21.1 77.3 0.0 127.7 84.0 0.0 154.6 72.9 0.0 52.1 67.8 39.7 0.0 0.0 0.0 116.7 147.6 53.3 0.0 63.7 41.6 122.5 0.0 0.0 258.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 76.3 0.0 0.0 58.4 0.0 0.0 0.0 0.0 74.7 0.0 0.0 25.9 0.0 0.0 222.4 19.7 0.0 0.0 0.0 43.7 0.0 0.0 0.0 0.0 66.5 50.9 93.6 0.0 0.0 RFC3 "MGC5276, RFC38" ENSG00000133119 "Replication factor C subunit 3" P40938 13 33818069-33966558 "Predicted intracellular proteins" "DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 285.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030149 Approved Supported Nucleoplasm,Vesicles No Yes "Cluster 27: Non-specific - Gene expression" "Cluster 63: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Vesicles" "HPA030149: AB_10602921" "unprognostic (3.86e-2)" "unprognostic (5.27e-2)" "unprognostic (1.12e-1)" "unprognostic (1.16e-2)" "unprognostic (5.76e-2)" "unprognostic (3.07e-3)" "unprognostic (3.32e-2)" "unprognostic (4.93e-2)" "unprognostic (9.02e-3)" "unprognostic (4.49e-1)" "unprognostic (6.46e-2)" "unprognostic (4.05e-2)" "unprognostic (5.24e-3)" "unprognostic (4.05e-2)" "unprognostic (1.79e-1)" "unprognostic (5.08e-2)" "unprognostic (2.86e-1)" 5.3 13.8 2.6 12.9 2.4 19.5 12.8 8.7 2.6 5.7 1.7 9.0 8.5 10.6 4.3 6.7 8.3 4.6 6.1 2.7 2.5 5.1 7.4 5.4 24.3 2.7 2.2 7.8 4.8 5.1 2.6 10.8 2.8 6.3 11.6 5.9 5.5 4.1 3.5 7.5 7.9 7.6 3.7 6.6 6.5 12.8 2.6 24.1 6.5 4.4 23.4 5.7 4.6 2.5 49.0 51.1 86.4 69.5 6.5 10.0 47.5 66.6 29.2 85.5 73.7 63.0 72.2 179.8 26.8 25.3 53.2 72.5 111.6 45.9 112.0 71.5 68.9 105.0 54.4 68.0 7.5 127.2 48.3 9.8 5.8 74.5 49.9 14.1 28.9 63.7 75.1 44.2 51.4 56.1 108.8 58.1 104.2 101.2 42.1 40.3 103.4 41.1 25.4 42.7 45.1 79.2 49.4 65.3 33.4 45.7 52.2 66.8 15.5 45.1 49.7 57.1 70.9 24.9 36.7 285.3 32.4 73.7 86.6 1.5 4.4 7.2 3.2 6.1 3.7 5.8 3.9 3.3 6.1 5.5 5.0 4.5 0.9 2.5 5.3 2.5 6.3 3.1 2.6 2.4 8.7 2.6 2.7 2.5 2.7 2.2 2.8 3.7 2.6 2.5 9.3 9.6 6.2 5.9 11.2 12.2 6.9 6.9 7.4 16.5 8.9 10.5 7.5 1.5 8.6 3.7 8.4 29.6 5.1 3.0 3.9 7.3 8.4 7.0 7.9 9.4 6.1 43.8 30.2 8.9 39.3 7.5 3.1 7.7 1.3 17.8 8.9 7.2 11.9 8.4 20.3 4.3 4.1 6.7 4.0 7.9 6.2 6.5 8.8 34.7 6.4 5.4 1.0 33.7 18.0 5.4 1.5 4.5 21.0 2.7 1.1 5.4 3.8 12.2 6.6 7.9 29.8 52.6 43.2 9.2 7.0 16.4 6.6 9.2 10.1 3.3 RFFL "CARP-2, CARP2, fring, rififylin, RNF189, RNF34L" ENSG00000092871 "Ring finger and FYVE like domain containing E3 ubiquitin protein ligase" Q8WZ73 17 35005990-35089319 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 93.8" "Cell type enhanced" "Detected in many" "Late spermatids: 109.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 119.5;Karpas-707: 112.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008096, HPA017910, HPA019492" Approved Approved Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "CAB008096: AB_2178607, HPA017910: AB_1856189, HPA019492: AB_1856190" "unprognostic (2.59e-1)" "unprognostic (2.87e-1)" "prognostic favorable (4.92e-4)" "unprognostic (1.24e-1)" "unprognostic (1.44e-1)" "unprognostic (1.79e-1)" "unprognostic (5.73e-3)" "unprognostic (4.34e-3)" "unprognostic (2.31e-1)" "unprognostic (9.26e-3)" "unprognostic (2.39e-1)" "unprognostic (2.63e-1)" "prognostic unfavorable (2.43e-5)" "unprognostic (1.44e-1)" "unprognostic (1.97e-1)" "unprognostic (8.68e-2)" "unprognostic (1.36e-1)" 9.9 7.1 23.9 17.7 59.5 41.4 12.2 49.2 38.0 11.9 11.6 26.7 28.1 9.6 8.8 35.9 9.3 19.4 8.2 24.3 36.4 17.7 48.3 12.6 17.6 74.2 53.0 8.5 18.8 12.1 6.8 11.9 71.2 18.3 23.2 21.1 13.1 12.7 15.8 7.5 22.8 13.3 48.6 19.2 23.3 26.6 52.2 26.0 39.0 13.1 29.4 20.3 16.2 93.8 22.9 43.4 10.7 15.0 21.6 28.1 6.1 15.6 25.8 15.5 18.7 15.4 50.5 7.0 19.4 21.4 33.0 32.2 18.4 30.8 22.4 119.5 11.2 40.5 11.0 38.6 18.0 20.2 20.0 19.0 18.8 23.7 46.9 22.6 15.6 21.2 18.2 112.2 16.0 8.7 4.9 19.4 15.2 51.1 24.9 17.3 18.7 43.2 22.8 48.6 12.0 15.8 8.9 10.3 9.1 24.4 15.9 27.7 29.7 8.6 14.9 8.7 24.1 41.4 33.0 9.4 36.4 15.8 7.4 28.6 16.2 33.7 16.8 9.3 20.6 7.8 18.5 16.3 10.8 6.9 16.0 14.5 55.3 14.4 9.9 1.3 29.6 15.5 23.9 59.5 49.2 38.0 24.3 36.4 74.2 53.0 71.2 48.6 52.2 93.8 6.5 41.7 27.4 0.0 12.6 6.0 11.9 7.4 5.2 10.6 9.9 3.8 1.3 20.0 17.3 0.0 14.6 9.4 12.1 33.7 1.9 8.4 41.0 13.0 6.8 6.6 15.0 23.8 0.0 15.1 1.7 9.3 23.0 18.1 25.3 5.4 9.3 35.2 7.2 6.7 0.0 26.4 6.1 16.3 16.9 109.1 3.1 16.1 1.8 0.0 22.6 20.8 25.7 0.0 0.0 16.8 19.3 4.5 12.9 28.1 16.7 20.4 11.7 34.9 6.6 15.2 5.7 15.9 10.8 16.2 6.1 5.1 23.7 3.1 18.9 39.5 RFT1 CDG1N ENSG00000163933 "RFT1 homolog" Q96AA3 3 53088483-53130453 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 39.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA060327, HPA069022" Approved Approved Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA060327: AB_2684253, HPA069022: AB_2732126" "unprognostic (5.74e-2)" "unprognostic (1.31e-1)" "unprognostic (1.35e-3)" "unprognostic (5.16e-3)" "unprognostic (2.08e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.69e-4)" "unprognostic (1.09e-1)" "unprognostic (1.22e-1)" "unprognostic (2.70e-1)" "unprognostic (2.81e-2)" "unprognostic (9.26e-2)" "unprognostic (6.48e-2)" "unprognostic (1.96e-1)" "unprognostic (1.22e-1)" "unprognostic (5.06e-2)" "unprognostic (3.54e-2)" 11.8 12.5 5.7 14.5 6.2 8.3 12.5 5.5 6.6 9.0 4.9 11.8 10.3 9.1 13.0 12.1 12.4 10.5 9.0 6.1 5.3 8.7 14.0 9.2 16.7 5.6 5.2 12.5 22.3 15.6 6.2 13.8 5.9 9.3 13.2 4.3 18.0 10.4 5.1 9.9 10.5 11.2 5.5 9.9 10.4 13.5 5.4 14.2 14.6 6.7 15.8 12.6 8.8 8.0 39.1 36.3 24.3 39.0 27.9 29.5 50.6 34.8 32.3 59.2 53.7 35.9 74.6 51.0 21.3 33.5 55.6 40.7 55.4 56.8 51.9 48.4 24.5 50.6 24.8 36.0 48.8 46.7 28.4 31.4 46.8 79.6 57.1 26.2 37.9 52.7 27.1 45.2 39.4 39.6 44.2 27.3 48.8 67.5 47.3 18.1 23.5 77.5 32.8 26.1 13.8 18.7 43.0 30.9 31.2 26.2 23.3 65.5 25.5 54.3 35.2 37.7 69.1 28.6 37.1 38.4 38.9 58.8 58.3 50.2 40.2 18.4 22.2 40.5 22.5 21.2 20.6 22.9 42.9 35.5 23.7 23.7 13.4 23.1 29.4 48.9 20.1 25.7 5.7 6.2 5.5 6.6 6.1 5.3 5.6 5.2 5.9 5.5 5.4 8.0 6.0 3.2 3.7 8.8 8.7 5.0 10.8 18.3 5.2 4.6 7.6 5.5 7.4 11.5 12.6 9.2 4.2 39.4 6.0 5.1 1.9 17.4 1.9 5.6 9.5 8.1 2.4 17.7 9.4 21.1 33.1 9.2 4.1 5.7 2.5 17.8 10.4 10.7 22.0 5.0 8.9 6.4 10.2 9.9 5.0 2.3 8.7 9.8 7.2 9.4 11.7 5.8 3.1 7.5 11.3 12.2 8.8 6.0 19.3 9.1 5.7 5.6 8.3 6.4 0.0 7.0 8.7 10.1 8.9 8.0 4.3 24.2 7.7 22.0 11.7 8.1 RFX1 EF-C ENSG00000132005 "Regulatory factor X1" P22670 19 13961530-14007039 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Early spermatids: 144.2;Late spermatids: 119.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 3.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048722, HPA052966" Approved Enhanced Nucleoplasm,Vesicles NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm Vesicles "HPA048722: AB_2680500, HPA052966: " "unprognostic (6.40e-2)" "unprognostic (1.26e-1)" "unprognostic (1.55e-3)" "unprognostic (2.63e-1)" "unprognostic (5.45e-2)" "prognostic favorable (2.42e-4)" "unprognostic (2.62e-1)" "unprognostic (1.71e-1)" "unprognostic (2.88e-1)" "unprognostic (1.61e-2)" "prognostic favorable (4.92e-4)" "unprognostic (1.35e-1)" "unprognostic (4.41e-2)" "unprognostic (1.83e-2)" "unprognostic (2.96e-1)" "unprognostic (1.50e-1)" "unprognostic (1.56e-2)" 5.8 6.1 1.2 2.0 1.2 2.4 6.4 4.3 2.4 9.8 0.5 6.0 2.3 7.0 0.8 7.7 7.4 1.3 7.4 1.3 1.6 7.2 8.7 6.6 1.7 1.1 1.1 8.8 7.8 2.2 16.6 1.5 0.7 8.0 0.5 1.1 7.3 1.6 7.9 7.4 7.1 0.6 0.5 9.2 6.7 22.1 2.0 1.7 9.9 0.8 1.0 5.9 7.7 0.8 3.3 3.2 1.7 2.1 1.0 1.2 5.1 1.8 1.1 2.0 1.7 3.3 3.2 1.8 3.6 0.9 1.7 4.2 1.2 1.2 0.7 2.0 7.0 2.1 3.8 3.0 1.8 2.1 4.3 0.9 1.3 1.8 1.0 1.7 1.5 1.5 5.5 1.9 1.0 4.8 3.9 4.6 3.9 1.7 4.8 3.4 1.8 2.6 1.9 1.7 6.9 3.7 3.0 2.6 2.6 0.9 2.9 2.2 1.8 3.4 2.8 3.8 3.1 4.7 2.3 1.2 2.7 2.0 3.1 0.2 1.1 0.6 0.4 0.4 0.4 1.0 0.5 0.5 0.6 1.1 0.5 0.6 3.7 1.1 0.7 1.2 0.3 0.4 1.2 1.2 4.3 2.4 1.3 1.6 1.1 1.1 0.7 0.5 2.0 0.8 26.1 16.0 8.9 3.6 25.9 5.6 8.8 8.7 10.8 29.6 25.9 21.1 11.2 14.3 11.3 22.0 35.5 9.7 34.4 24.0 9.8 11.9 144.2 14.3 31.2 13.4 16.7 29.9 12.0 9.6 12.7 14.5 14.3 25.2 11.4 10.2 20.3 17.5 10.7 23.5 10.2 19.5 10.2 24.5 12.0 119.2 25.7 17.2 1.8 10.3 15.4 13.4 14.4 4.5 4.9 9.7 14.0 27.8 19.9 6.8 13.8 17.4 4.6 46.7 13.1 25.8 13.1 33.9 20.5 7.8 7.5 19.0 20.4 8.3 15.6 6.7 RFX3 ENSG00000080298 "Regulatory factor X3" P48380 9 3218297-3526004 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 31.3;choroid plexus: 40.7" "Cell type enhanced" "Detected in many" "Astrocytes: 394.4;Early spermatids: 182.8;Excitatory neurons: 333.6;Inhibitory neurons: 208.8;Microglial cells: 188.3;Oligodendrocyte precursor cells: 256.9;Oligodendrocytes: 179.6;Respiratory ciliated cells: 150.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 26.4;HDLM-2: 16.2;SCLC-21H: 14.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035689 Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm Vesicles "HPA035689: AB_10671224" "prognostic favorable (1.47e-4)" "unprognostic (8.78e-2)" "unprognostic (1.18e-1)" "unprognostic (5.52e-2)" "unprognostic (2.27e-2)" "unprognostic (1.50e-1)" "unprognostic (8.26e-3)" "unprognostic (3.06e-2)" "unprognostic (1.68e-1)" "unprognostic (6.49e-2)" "unprognostic (7.58e-3)" "unprognostic (1.31e-2)" "unprognostic (1.64e-1)" "unprognostic (1.20e-1)" "unprognostic (2.31e-1)" "unprognostic (2.52e-1)" "unprognostic (8.89e-3)" 3.0 1.9 10.0 2.0 14.6 6.3 3.3 21.7 31.3 4.2 40.7 2.6 2.2 3.2 2.7 1.4 11.5 2.2 2.0 27.6 11.0 2.1 1.6 4.2 3.4 14.0 21.3 3.7 2.4 3.3 4.4 2.7 8.2 3.0 2.4 9.0 2.2 1.8 3.2 2.4 2.8 1.5 17.6 3.0 3.1 21.2 13.2 6.3 2.7 1.5 3.7 2.2 2.9 11.8 2.5 3.3 26.4 6.4 1.0 1.1 2.6 1.0 2.9 2.3 1.7 1.0 3.1 3.9 1.1 1.4 1.8 1.4 6.5 2.8 3.9 16.2 1.8 7.3 3.6 2.2 1.3 1.5 1.0 1.6 1.3 2.7 4.4 4.4 4.0 5.0 1.4 3.9 2.4 1.9 4.7 5.4 7.0 2.1 1.4 4.9 1.8 1.0 3.6 1.9 14.1 6.2 1.5 0.8 2.4 5.1 1.3 3.9 2.5 1.7 3.8 0.9 1.6 1.3 0.6 7.8 1.8 1.7 1.8 2.4 2.2 4.7 5.9 3.3 3.6 4.1 5.3 4.7 2.2 5.1 3.6 4.5 6.1 4.0 1.0 3.2 7.2 2.7 10.0 14.6 21.7 31.3 27.6 11.0 14.0 21.3 8.2 17.6 13.2 11.8 15.7 6.4 7.7 394.4 20.9 5.0 8.0 6.4 6.2 24.7 7.7 6.2 6.9 2.8 23.2 3.7 25.0 2.0 11.3 2.4 0.0 3.9 182.8 89.4 16.1 18.5 141.1 7.4 333.6 2.5 2.7 7.3 7.1 11.2 6.3 8.4 15.0 1.0 3.1 38.7 208.8 9.4 6.1 7.3 5.7 120.8 7.2 8.6 1.8 188.3 5.4 14.5 5.2 256.9 179.6 4.2 4.9 7.5 8.1 6.1 2.9 2.2 150.3 24.7 0.0 22.8 11.4 8.9 5.2 4.9 6.3 1.4 12.2 5.9 6.0 3.9 RFX5 ENSG00000143390 "Regulatory factor X5" P48382 1 151340640-151347326 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018519, HPA079241" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm Vesicles "HPA018519: AB_1856209, HPA079241: " "unprognostic (1.17e-3)" "unprognostic (1.62e-1)" "unprognostic (2.61e-1)" "unprognostic (3.21e-2)" "unprognostic (2.68e-2)" "unprognostic (2.49e-2)" "unprognostic (3.73e-2)" "unprognostic (2.09e-3)" "unprognostic (2.99e-2)" "unprognostic (1.96e-1)" "unprognostic (8.29e-2)" "unprognostic (4.42e-2)" "unprognostic (5.66e-3)" "unprognostic (2.00e-3)" "unprognostic (3.43e-2)" "unprognostic (4.03e-2)" "unprognostic (3.05e-2)" 18.4 25.6 13.3 43.3 13.7 24.0 14.9 17.8 13.2 18.2 11.7 22.7 31.6 22.0 13.1 18.3 18.4 23.4 18.3 12.3 16.8 18.3 13.1 27.9 67.7 17.1 17.6 10.1 9.6 22.1 18.1 12.4 18.5 20.4 28.1 14.6 16.0 25.1 17.0 13.1 26.1 31.8 15.4 50.7 19.6 15.5 15.7 50.5 23.7 23.8 71.8 26.5 11.4 13.3 37.7 41.8 57.6 32.8 27.6 24.0 12.6 17.8 30.0 43.6 57.7 13.7 50.9 145.2 63.9 21.5 42.6 59.5 24.9 34.4 31.9 177.4 39.7 54.8 89.4 23.0 17.7 48.9 59.4 25.2 18.8 28.8 13.2 35.7 39.9 92.0 26.8 88.3 33.8 34.2 78.7 36.2 41.9 30.5 21.2 97.1 32.3 80.1 42.0 49.1 20.4 60.0 35.7 55.0 52.8 69.2 51.6 114.3 39.9 23.8 25.1 11.8 33.7 110.9 118.2 168.6 37.8 26.4 31.3 5.6 22.6 11.5 17.4 28.2 15.3 47.9 13.9 17.4 47.4 53.3 10.9 12.2 3.1 31.4 30.8 25.1 28.5 21.5 13.3 13.7 17.8 13.2 12.3 16.8 17.1 17.6 18.5 15.4 15.7 13.3 8.4 9.6 7.5 4.9 32.0 6.6 12.5 11.4 14.2 7.6 9.4 6.5 5.1 8.6 12.1 7.3 0.0 8.8 16.9 3.8 9.8 15.7 8.4 7.5 6.3 9.9 4.2 16.6 3.2 9.2 3.4 6.1 5.6 12.8 24.1 9.4 10.8 7.3 12.4 1.7 7.0 5.1 10.2 18.5 15.7 17.9 5.0 13.3 5.4 8.4 40.8 7.2 21.6 3.0 2.4 8.6 2.7 9.8 9.5 14.1 11.2 10.7 7.4 2.7 6.6 5.3 5.7 15.5 7.5 14.2 6.1 3.4 13.7 15.7 7.3 14.6 RGL1 RGL ENSG00000143344 "Ral guanine nucleotide dissociation stimulator like 1" Q9NZL6 1 183636085-183928532 "Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 133.5;Excitatory neurons: 176.1;Inhibitory neurons: 141.8;Kupffer cells: 109.1;Oligodendrocytes: 184.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 35.0;HSkMC: 54.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019788 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA019788: AB_1856215" "unprognostic (3.08e-1)" "unprognostic (5.25e-3)" "unprognostic (8.73e-2)" "unprognostic (1.24e-2)" "unprognostic (2.34e-1)" "unprognostic (4.79e-3)" "prognostic unfavorable (1.49e-5)" "prognostic favorable (4.32e-4)" "unprognostic (1.12e-1)" "unprognostic (6.34e-2)" "unprognostic (5.77e-3)" "unprognostic (4.59e-2)" "unprognostic (2.63e-3)" "unprognostic (4.87e-2)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (2.88e-2)" 24.7 16.8 22.7 19.9 25.3 1.6 17.1 17.3 27.0 18.6 21.5 11.3 8.7 18.0 6.3 10.6 15.2 22.5 17.0 27.1 21.7 28.6 16.2 20.9 22.9 23.7 20.7 19.2 6.8 8.9 9.5 16.1 17.4 13.2 12.8 15.7 7.7 11.6 2.7 8.9 10.6 22.2 21.1 45.4 6.9 14.7 23.9 8.7 9.1 7.7 10.1 18.7 8.9 28.5 0.3 1.5 26.3 4.0 35.0 16.1 26.7 12.4 20.6 5.5 6.8 12.2 0.7 0.3 11.3 8.8 4.3 0.6 1.8 3.1 5.4 0.4 1.9 0.2 2.6 12.6 9.3 0.4 1.5 54.9 0.7 14.0 3.3 26.2 20.8 2.7 0.0 19.6 11.8 0.1 2.9 0.2 9.6 0.9 0.7 23.7 1.7 24.3 1.5 7.5 3.3 7.9 3.9 4.2 2.1 8.5 0.2 0.3 15.3 7.9 3.1 24.7 6.8 2.0 0.5 0.1 8.3 0.3 22.2 0.0 0.8 0.0 0.0 2.1 0.1 0.0 0.3 0.0 0.9 0.0 0.4 0.2 0.0 0.0 0.8 0.0 0.2 0.5 22.7 25.3 17.3 27.0 27.1 21.7 23.7 20.7 17.4 21.1 23.9 28.5 9.4 9.6 12.3 133.5 1.6 8.2 2.2 2.5 5.2 5.1 6.7 4.6 8.7 5.7 9.0 5.5 0.0 5.1 0.6 2.6 5.9 4.0 13.8 7.9 23.2 19.7 0.0 0.4 176.1 0.9 2.6 22.0 3.6 24.1 3.8 11.0 41.4 2.6 43.3 8.4 141.8 0.8 4.1 109.1 50.4 17.6 13.1 43.7 5.4 76.8 1.7 23.0 0.0 38.7 184.3 1.0 0.1 20.7 0.1 3.5 2.8 30.1 14.2 2.0 26.3 1.2 9.7 4.0 2.5 5.8 4.7 5.2 2.2 13.1 0.6 2.9 RGPD1 RGP1 ENSG00000187627 "RANBP2 like and GRIP domain containing 1" P0DJD0 2 86907953-87013976 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 8.6;placenta: 6.8;testis: 15.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.3;Early spermatids: 2.5;Excitatory neurons: 4.3;granulocytes: 3.8;Inhibitory neurons: 4.0;Microglial cells: 2.8;Oligodendrocytes: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 6.6;MOLT-4: 10.7;NTERA-2: 3.1;RPMI-8226: 2.4;SuSa: 5.3" "HPA049497, HPA051675, HPA067564" Uncertain Approved "Nuclear membrane,Vesicles" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 60: Granulocytes - Receptor signaling" "Nuclear membrane, Vesicles" "HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (8.24e-2)" "unprognostic (6.05e-2)" "unprognostic (6.41e-2)" "unprognostic (1.39e-2)" "unprognostic (9.06e-2)" "unprognostic (6.28e-2)" "unprognostic (1.80e-1)" "unprognostic (2.42e-2)" "unprognostic (1.48e-1)" "unprognostic (2.30e-1)" "unprognostic (1.88e-5)" "unprognostic (2.23e-1)" "unprognostic (2.22e-2)" "unprognostic (5.36e-3)" "unprognostic (1.99e-2)" 0.1 0.1 0.2 0.1 0.2 0.0 0.1 2.0 0.4 8.6 0.0 0.1 0.0 0.1 0.0 0.1 0.4 0.0 0.1 0.1 0.6 0.1 0.1 0.1 0.2 1.5 0.3 0.1 1.6 0.3 1.5 6.8 1.2 0.1 0.0 2.1 0.2 0.0 0.2 0.1 0.3 0.0 0.1 0.2 0.3 15.4 0.6 0.9 0.2 0.0 0.5 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 10.7 0.2 3.1 0.1 0.0 0.1 0.0 2.4 0.0 0.0 0.0 0.7 0.1 0.0 0.0 5.3 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.8 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 2.0 0.4 0.1 0.6 1.5 0.3 1.2 0.1 0.6 0.3 0.1 0.0 0.5 1.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 2.5 0.0 0.0 0.5 0.0 0.4 4.3 0.0 0.0 0.8 0.0 0.0 3.8 0.0 0.0 0.0 0.1 0.0 4.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 2.8 0.0 0.2 0.0 1.5 1.8 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.2 0.8 0.0 0.0 0.3 1.0 0.0 0.0 0.0 RGPD2 "RANBP2L2, RGP2" ENSG00000185304 "RANBP2 like and GRIP domain containing 2" P0DJD1 2 87755960-87825952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 16.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 7.0;dendritic cells: 5.1;Early spermatids: 5.5;Excitatory neurons: 4.3;Late spermatids: 6.7;Plasma cells: 7.5;T-cells: 4.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "T-reg: 9.6" "Lineage enriched" "Detected in single" 11 "T-cells: 9.6" "Cell line enhanced" "Detected in some" "BEWO: 11.0;JURKAT: 5.4;MOLT-4: 13.3;NTERA-2: 5.4;SuSa: 15.2;THP-1: 5.2" "HPA049497, HPA051675, HPA067564" Uncertain Approved "Nuclear membrane,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear membrane, Vesicles" "HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (4.49e-2)" "unprognostic (1.99e-1)" "unprognostic (1.26e-2)" "unprognostic (2.04e-2)" "unprognostic (1.69e-1)" "unprognostic (2.05e-1)" "unprognostic (7.46e-3)" "unprognostic (1.71e-1)" "unprognostic (1.72e-2)" "unprognostic (4.10e-2)" "unprognostic (4.24e-1)" "unprognostic (1.32e-1)" "unprognostic (3.83e-6)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (5.09e-2)" "unprognostic (2.59e-1)" 1.8 2.8 0.8 1.3 0.7 8.9 1.4 2.6 1.4 10.5 1.6 1.7 2.0 1.4 0.4 0.9 3.2 0.4 1.2 0.6 0.6 1.2 9.6 2.6 2.2 1.7 0.8 2.6 7.9 0.3 5.8 9.5 2.0 1.7 0.7 3.4 1.3 0.7 1.0 1.2 3.7 0.5 0.4 3.2 2.7 16.6 1.0 5.6 1.8 0.3 2.5 0.8 1.6 0.7 0.0 0.0 0.6 0.0 0.0 0.0 11.0 0.5 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 2.6 0.2 0.0 0.1 0.0 5.4 4.0 0.3 0.0 0.4 13.3 0.0 5.4 2.4 0.0 0.3 0.0 0.2 0.0 0.0 0.0 2.7 4.5 0.1 0.0 15.2 0.0 5.2 0.1 0.8 0.1 0.0 0.0 2.5 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.3 0.6 2.1 0.4 0.0 0.8 1.0 0.2 0.3 0.1 0.0 0.0 9.6 0.3 0.8 0.7 2.6 1.4 0.6 0.6 1.7 0.8 2.0 0.4 1.0 0.7 0.9 0.0 1.1 1.0 4.0 0.1 0.0 0.0 0.0 0.5 0.1 0.3 7.0 0.0 0.0 0.0 0.0 0.4 5.1 0.2 0.0 0.1 5.5 1.7 2.3 0.7 0.0 0.0 4.3 0.2 0.6 0.9 0.5 0.7 0.0 0.2 0.4 0.3 0.1 0.0 3.4 0.0 0.0 0.0 0.4 6.7 0.0 1.7 0.0 1.9 0.0 0.0 0.0 1.5 2.2 0.1 0.0 0.0 7.5 0.1 0.0 0.1 0.8 1.7 0.0 1.0 0.8 2.5 0.6 0.0 0.0 1.0 4.5 0.1 0.0 0.0 RGPD3 RGP3 ENSG00000153165 "RANBP2 like and GRIP domain containing 3" A6NKT7 2 106391290-106468413 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 6.9" "Cell type enriched" "Detected in some" 4 "Early spermatids: 19.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HEL: 1.5;MOLT-4: 4.6;RPMI-8226: 1.4" "HPA049497, HPA051675, HPA067564" Uncertain Approved "Nuclear membrane,Vesicles" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nuclear membrane, Vesicles" "HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (2.91e-1)" "unprognostic (1.62e-1)" "unprognostic (5.51e-2)" "unprognostic (6.61e-2)" "unprognostic (2.53e-1)" "unprognostic (1.33e-1)" "unprognostic (1.26e-1)" "unprognostic (6.86e-2)" "unprognostic (3.10e-1)" "unprognostic (2.49e-2)" "unprognostic (3.70e-1)" "unprognostic (3.44e-1)" "unprognostic (4.74e-3)" "unprognostic (5.05e-2)" "unprognostic (3.70e-1)" "unprognostic (3.42e-1)" "unprognostic (1.34e-1)" 0.2 0.1 0.4 0.1 0.4 0.4 0.2 0.4 0.5 0.1 0.9 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.4 0.4 0.7 0.7 0.2 0.1 1.0 0.6 0.2 0.2 0.2 0.5 0.2 1.1 0.2 0.1 0.9 0.2 0.2 0.2 0.3 0.1 0.1 0.4 0.6 0.1 6.9 0.7 1.9 0.1 0.1 0.2 0.3 0.1 0.5 0.1 0.2 0.2 0.2 0.1 0.2 0.1 0.2 0.2 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.5 0.1 0.6 0.1 0.2 0.1 0.0 1.5 0.2 0.2 0.1 0.0 0.0 0.0 0.1 0.5 0.1 0.1 0.1 0.4 0.3 0.0 0.2 0.1 4.6 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.1 0.3 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.4 0.4 0.5 0.4 0.4 1.0 0.6 1.1 0.4 0.7 0.5 0.0 0.0 1.1 1.6 0.1 0.1 0.1 0.0 0.0 1.6 0.0 0.0 2.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.1 0.1 0.5 0.0 0.0 2.4 0.2 0.0 0.4 0.0 0.1 1.3 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.3 4.4 0.0 0.1 0.0 1.9 0.0 0.0 0.0 2.0 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.7 0.2 0.0 0.0 0.4 3.2 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 RGPD4 "DKFZp686P0288, RGP4" ENSG00000196862 "RANBP2 like and GRIP domain containing 4" Q7Z3J3 2 107826892-107892544 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 3.7" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 5.8;Early spermatids: 10.4;Late spermatids: 3.1;Spermatocytes: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049497, HPA051675, HPA067564" Uncertain Uncertain "Nuclear membrane,Vesicles" NA NA "Cluster 77: Retina - Visual perception" "Cluster 43: Cardiomyocytes - Nuclear processes" "Nuclear membrane, Vesicles" "HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (4.96e-2)" "unprognostic (3.04e-1)" "unprognostic (4.38e-1)" "unprognostic (1.31e-1)" "unprognostic (2.46e-1)" "unprognostic (1.29e-1)" "unprognostic (3.05e-3)" "unprognostic (7.79e-2)" "unprognostic (1.52e-1)" "unprognostic (4.47e-1)" "unprognostic (6.05e-2)" "unprognostic (2.69e-2)" 0.1 0.2 0.2 0.2 0.2 0.1 0.1 0.1 0.3 0.1 0.2 0.1 0.2 0.2 0.8 0.0 0.1 0.1 0.0 0.2 0.2 0.2 0.1 0.1 0.2 0.1 0.3 0.2 0.0 0.1 0.0 0.0 0.2 0.1 0.1 1.0 0.0 0.1 0.2 0.1 0.2 0.0 0.1 0.2 0.3 3.7 0.5 0.3 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.1 0.1 0.1 0.2 0.0 0.2 0.1 0.2 0.2 0.5 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.3 0.2 0.3 0.0 0.3 0.2 0.0 0.1 0.3 0.1 0.2 0.0 0.3 0.1 0.0 0.2 0.1 0.1 0.3 0.1 0.1 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.3 0.2 0.2 0.1 0.3 0.2 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.9 0.0 0.0 1.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 2.8 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 RGPD5 "BS-63, DKFZp686I1842, RGP5" ENSG00000015568 "RANBP2 like and GRIP domain containing 5" Q99666 2 109792758-109857705 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 20.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA045704, HPA049497, HPA051675, HPA067564" Uncertain Uncertain "Nuclear membrane,Vesicles" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 52: Non-specific - Transcription" "Nuclear membrane, Vesicles" "HPA045704: AB_2679427, HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (2.50e-2)" "unprognostic (1.55e-1)" "unprognostic (3.49e-1)" "unprognostic (2.23e-1)" "unprognostic (4.23e-2)" "unprognostic (3.19e-1)" "unprognostic (3.19e-3)" "unprognostic (3.19e-1)" 10.2 8.3 12.0 5.8 16.4 13.8 10.3 5.9 21.9 8.1 8.1 8.2 7.4 10.4 17.5 5.4 7.6 7.2 8.9 16.5 14.7 7.3 6.8 10.3 6.0 3.5 3.4 13.0 13.5 14.7 8.2 11.1 4.3 12.3 7.2 22.3 7.0 9.6 6.5 11.6 7.4 7.4 2.7 6.4 7.0 41.2 12.6 3.8 14.4 9.7 5.3 7.5 3.9 14.0 24.3 7.8 26.0 19.5 7.7 8.0 1.2 19.3 16.1 13.8 11.2 20.9 7.8 0.6 12.4 11.7 14.6 8.0 14.3 7.0 17.3 3.7 6.4 18.5 4.1 10.2 8.8 1.5 3.1 8.5 9.5 13.3 14.2 14.5 9.4 7.6 8.8 5.4 10.7 4.5 4.0 0.6 12.7 3.0 9.9 4.3 14.4 0.1 10.4 13.7 31.9 4.5 10.0 1.5 14.0 16.5 0.5 5.4 15.6 14.3 21.1 1.0 14.1 12.2 0.5 0.6 11.7 0.2 4.6 5.4 2.0 2.5 1.9 1.0 3.6 1.7 1.5 2.1 1.4 4.2 2.0 2.1 5.5 2.0 1.2 2.5 1.9 0.6 12.0 16.4 5.9 21.9 16.5 14.7 3.5 3.4 4.3 2.7 12.6 14.0 12.9 3.2 11.8 0.0 9.0 3.4 5.0 0.8 2.8 17.7 2.5 1.4 13.8 0.0 3.7 12.9 16.7 2.4 15.9 1.7 0.0 1.7 4.1 12.3 12.0 7.4 5.3 0.0 7.3 1.0 1.8 7.4 5.1 18.6 0.0 9.4 4.2 0.9 1.8 3.3 4.5 1.4 0.0 2.9 6.5 1.7 2.5 6.6 1.8 1.0 0.9 3.8 0.0 0.0 0.2 1.5 1.7 1.2 10.7 5.5 1.7 0.4 2.6 20.3 0.0 9.7 7.8 4.1 2.9 1.2 3.3 4.4 12.4 1.6 1.0 7.3 RGPD6 RGP6 ENSG00000183054 "RANBP2 like and GRIP domain containing 6" Q99666 2 110513802-110577222 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 9.6;Alveolar cells type 2: 17.1;Club cells: 8.1;Excitatory neurons: 10.7;Inhibitory neurons: 7.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 11.5;SCLC-21H: 10.5" "HPA045704, HPA049497, HPA051675, HPA067564" Uncertain Uncertain "Nuclear membrane,Vesicles" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" "Nuclear membrane, Vesicles" "HPA045704: AB_2679427, HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (1.11e-2)" "unprognostic (6.38e-2)" "unprognostic (1.18e-1)" "unprognostic (3.67e-2)" "unprognostic (1.53e-1)" "unprognostic (3.22e-1)" "unprognostic (2.91e-2)" "unprognostic (4.14e-4)" "unprognostic (2.04e-1)" 12.9 8.4 5.0 0.7 2.3 6.3 13.3 6.3 6.4 13.3 6.4 11.5 1.5 9.7 0.9 7.4 12.2 0.0 12.9 2.3 4.9 9.5 14.0 14.4 2.3 4.5 1.5 15.2 18.1 2.0 22.9 1.8 2.8 14.8 0.6 1.9 9.7 0.1 14.7 17.2 12.0 1.0 3.9 9.6 11.8 31.9 2.5 0.7 14.2 2.1 0.7 10.8 10.7 7.6 7.0 2.6 1.2 2.0 0.0 0.5 2.9 1.3 0.0 0.8 0.1 5.7 1.5 0.4 4.2 2.5 3.4 5.2 0.2 2.4 0.0 1.6 11.5 6.8 0.9 1.0 0.1 2.2 0.3 0.4 1.5 1.3 3.1 1.0 0.0 2.1 2.7 2.0 0.0 3.7 1.8 0.0 7.6 1.4 6.7 2.6 4.1 0.0 2.6 0.7 10.5 4.8 1.1 0.2 3.1 4.1 0.1 0.4 1.5 1.4 4.0 0.4 6.0 3.8 0.4 0.5 2.6 0.0 2.5 4.7 1.5 2.0 1.6 0.8 2.4 2.0 2.3 1.7 1.0 3.1 2.3 1.4 4.7 1.5 1.8 2.2 0.5 0.3 5.0 2.3 6.3 6.4 2.3 4.9 4.5 1.5 2.8 3.9 2.5 7.6 0.1 9.6 17.1 0.0 0.3 0.9 0.2 0.0 0.0 0.0 0.1 0.1 1.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 10.7 0.0 0.0 0.8 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 7.0 0.0 0.0 0.0 0.3 0.3 0.0 0.5 1.8 1.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.2 0.6 0.2 0.0 0.3 0.0 0.4 0.0 0.0 0.3 RGPD8 "RanBP2alpha, RANBP2L1" ENSG00000169629 "RANBP2 like and GRIP domain containing 8" O14715 2 112368369-112434488 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 15.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Early spermatids: 24.3;Excitatory neurons: 9.8;Late spermatids: 10.1;Microglial cells: 9.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 16.2;hTEC/SVTERT24-B: 13.4" "HPA045704, HPA049497, HPA051675, HPA067564" Uncertain Uncertain "Nuclear membrane,Vesicles" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 36: HEL - Hemostasis" "Cluster 59: Non-specific - Transcription" "Nuclear membrane, Vesicles" "HPA045704: AB_2679427, HPA049497: AB_2680794, HPA051675: AB_2681570, HPA067564: AB_2685862" "unprognostic (1.37e-1)" "unprognostic (2.33e-1)" "unprognostic (1.05e-1)" "unprognostic (1.55e-1)" "unprognostic (3.62e-1)" "unprognostic (7.61e-2)" "unprognostic (2.65e-1)" "unprognostic (7.15e-3)" "unprognostic (3.17e-3)" "unprognostic (3.02e-2)" "unprognostic (2.78e-1)" "unprognostic (2.57e-1)" "unprognostic (9.18e-3)" "unprognostic (1.39e-1)" "unprognostic (1.31e-1)" "unprognostic (1.70e-1)" "unprognostic (1.05e-2)" 4.3 1.8 2.7 2.8 3.6 10.6 4.5 8.6 7.6 2.8 4.5 2.1 1.6 3.1 5.4 1.4 2.2 2.9 1.8 3.7 3.5 2.4 5.1 3.3 2.4 2.2 2.4 3.2 3.0 2.2 2.6 3.3 1.9 2.6 2.3 7.9 2.5 2.9 1.7 3.8 2.1 2.6 1.1 3.0 1.7 15.6 2.6 3.2 2.4 2.2 3.0 2.6 1.6 5.5 6.1 2.6 4.3 2.6 1.6 3.6 0.1 2.4 1.9 2.3 1.5 5.3 0.4 0.0 1.7 4.0 2.0 2.9 12.3 1.7 2.4 8.7 4.0 16.2 4.5 4.1 2.2 0.1 0.2 0.6 2.2 13.4 3.4 5.7 1.9 2.8 8.4 0.4 3.6 2.5 8.7 2.1 3.0 0.9 3.7 0.0 0.5 0.1 1.3 2.5 2.7 0.5 8.1 0.1 1.7 3.0 1.2 6.8 8.9 1.3 1.8 6.9 4.4 0.0 0.0 0.0 0.5 2.9 0.3 1.3 0.4 0.4 1.0 0.3 1.4 0.5 0.7 0.9 0.4 0.6 1.0 0.6 0.3 0.5 0.8 0.7 0.4 0.3 2.7 3.6 8.6 7.6 3.7 3.5 2.2 2.4 1.9 1.1 2.6 5.5 1.0 9.6 3.6 1.6 2.8 0.4 0.4 0.2 5.2 0.8 0.3 0.3 8.0 1.5 1.9 0.0 2.1 0.2 0.7 0.1 0.0 0.5 24.3 0.6 0.5 1.5 0.0 2.5 9.8 1.1 0.1 2.2 2.6 0.6 5.1 0.6 0.7 0.2 0.4 0.0 7.0 0.4 0.0 0.6 0.8 10.1 0.3 2.0 0.0 9.4 2.3 0.4 0.0 7.5 5.2 0.9 0.0 0.0 2.4 0.0 0.0 0.1 6.7 0.7 0.0 0.9 0.9 6.8 2.7 2.7 0.0 0.4 3.1 0.0 0.0 0.3 RGR RP44 ENSG00000148604 "Retinal G protein coupled receptor" P47804 10 84230666-84259960 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "retina: 139.0" "Cell type enriched" "Detected in some" 29 "Muller glia cells: 1475.8" "Cancer enriched" "Detected in single" 4 "glioma: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "midbrain: 23.4;olfactory bulb: 49.7;thalamus: 27.3" HPA059149 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Plasma membrane, Cytosol" "HPA059149: " "unprognostic (9.28e-2)" "unprognostic (1.05e-1)" "unprognostic (1.37e-1)" "unprognostic (9.53e-2)" "unprognostic (4.57e-2)" "unprognostic (1.57e-1)" "unprognostic (1.59e-1)" "unprognostic (1.97e-1)" 0.2 0.0 11.9 0.0 11.9 0.0 0.1 4.4 14.6 0.0 14.4 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.5 7.4 8.5 0.0 0.0 0.2 0.0 5.2 8.2 0.0 0.0 0.0 0.4 0.0 5.4 0.0 0.0 139.0 0.1 0.0 0.0 0.1 0.1 0.0 3.1 0.0 0.2 0.9 10.1 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 11.9 4.4 14.6 7.4 8.5 5.2 8.2 5.4 3.1 10.1 6.2 0.0 0.0 0.0 6.8 0.0 0.0 0.1 0.0 0.0 20.6 0.1 0.1 0.4 0.0 0.0 0.0 31.3 0.0 0.0 0.1 0.0 0.0 8.6 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.1 0.0 0.0 0.0 0.0 10.6 0.3 0.0 0.0 0.0 0.0 1475.8 0.0 2.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.6 0.0 2.8 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RGS14 ENSG00000169220 "Regulator of G protein signaling 14" O43566 5 177357924-177372596 "Predicted intracellular proteins" "Cell cycle, Cell division" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 110.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 72.8;Proximal tubular cells: 113.7;Squamous epithelial cells: 95.8;Suprabasal keratinocytes: 115.1" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 110.4;cerebral cortex: 67.9;hippocampal formation: 56.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 112.5;HMC-1: 95.4;NB-4: 44.8;RPMI-8226: 57.9" "Group enriched" "Detected in many" 10 "amygdala: 66.0;basal ganglia: 57.9;cerebral cortex: 46.8;hippocampal formation: 93.6;white matter: 23.8" "Region enhanced" "Detected in many" "basal ganglia: 102.1" "HPA046847, HPA061819" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Intermediate filaments" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Vesicles, Plasma membrane, Intermediate filaments" "HPA046847: AB_2679836, HPA061819: " "unprognostic (6.05e-3)" "unprognostic (1.65e-2)" "unprognostic (8.57e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (6.97e-4)" "unprognostic (7.27e-2)" "prognostic unfavorable (1.84e-6)" "unprognostic (1.95e-2)" "unprognostic (4.34e-2)" "unprognostic (2.04e-3)" "unprognostic (2.71e-1)" "unprognostic (1.28e-1)" "unprognostic (9.95e-2)" "unprognostic (3.17e-2)" "unprognostic (1.66e-1)" "unprognostic (1.17e-2)" "unprognostic (2.78e-2)" 3.5 2.8 16.0 13.9 110.4 22.4 2.9 0.0 67.9 3.1 1.8 3.7 6.3 2.3 0.4 10.0 7.7 4.3 1.3 56.4 4.5 8.5 28.7 5.5 18.1 0.0 0.4 1.1 3.7 1.5 2.4 1.4 0.1 3.5 0.9 0.0 6.2 2.1 2.6 6.1 11.0 1.8 0.1 27.7 4.9 1.9 15.2 16.3 6.1 0.9 6.6 4.1 5.0 3.2 5.4 1.1 2.3 1.4 0.1 0.0 3.7 0.2 0.0 0.5 0.6 3.7 10.4 13.3 7.3 0.4 1.3 10.6 0.2 3.8 0.0 112.5 0.5 20.7 1.0 4.7 0.9 16.3 95.4 1.8 1.1 0.6 0.7 1.4 0.6 14.9 3.5 26.5 0.2 0.4 21.7 44.8 1.7 5.4 2.8 10.2 0.3 57.9 1.5 1.6 0.4 1.9 0.4 0.4 8.8 0.0 3.5 25.2 1.1 0.2 1.9 0.0 9.7 13.9 7.1 5.8 1.6 30.3 2.4 70.6 39.9 148.8 62.4 37.9 63.0 27.7 57.9 57.8 39.8 26.6 47.4 43.1 140.0 23.6 41.2 17.6 60.9 43.9 16.0 110.4 0.0 67.9 56.4 4.5 0.0 0.4 0.1 0.1 15.2 3.2 5.3 6.4 4.4 2.6 27.3 68.8 23.9 15.4 72.8 0.7 8.9 11.8 2.3 37.1 5.6 11.0 2.1 3.9 41.4 4.2 31.3 11.4 0.6 19.5 2.0 6.5 4.8 7.4 4.6 16.7 10.4 5.4 12.2 8.1 24.7 2.8 8.2 64.0 26.1 0.0 1.5 10.0 10.2 17.0 23.3 1.5 2.8 18.2 21.4 6.5 18.1 9.9 48.4 0.5 0.3 12.8 17.2 2.2 18.0 14.1 16.8 113.7 11.7 2.0 0.0 1.6 4.6 0.1 20.3 95.8 115.1 3.3 51.2 1.1 4.4 20.0 RGS17 "RGS-17, RGSZ2" ENSG00000091844 "Regulator of G protein signaling 17" Q9UGC6 6 153004459-153131282 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.5" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 41.9;Excitatory neurons: 54.4;Inhibitory neurons: 57.2;Oligodendrocyte precursor cells: 62.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 7.9;hTERT-HME1: 7.0;LHCN-M2: 8.7;RH-30: 6.7;U-87 MG: 9.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022276, HPA056493" Approved Approved Vesicles NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA022276: AB_10794628, HPA056493: AB_2683152" "unprognostic (2.77e-2)" "unprognostic (6.81e-2)" "unprognostic (3.11e-1)" "unprognostic (1.99e-1)" "unprognostic (1.81e-2)" "unprognostic (1.54e-1)" "unprognostic (1.03e-3)" "unprognostic (3.12e-1)" "unprognostic (3.79e-2)" "unprognostic (7.95e-3)" "unprognostic (1.92e-1)" "unprognostic (5.33e-2)" "unprognostic (5.96e-12)" "unprognostic (2.70e-2)" "unprognostic (2.53e-1)" "unprognostic (1.75e-1)" "unprognostic (1.04e-1)" 0.8 0.3 2.0 0.4 1.8 1.3 0.6 3.5 1.8 1.4 0.0 0.4 0.5 0.5 0.2 1.6 0.5 1.1 0.2 1.8 3.2 0.6 0.1 0.3 0.5 1.7 3.1 0.9 1.0 0.0 1.9 0.1 1.4 1.3 0.4 1.7 0.7 0.3 0.1 0.6 0.5 0.2 2.2 0.3 0.9 0.9 2.8 0.6 2.3 0.0 0.1 0.9 0.7 1.2 0.1 2.0 2.2 0.2 1.0 7.9 0.1 0.2 0.7 0.5 1.3 0.0 0.3 0.3 0.4 0.4 4.2 0.3 2.0 1.9 1.0 0.2 0.3 0.4 0.4 0.1 1.9 0.2 1.0 2.3 0.1 3.3 7.0 1.8 3.8 1.1 0.1 0.3 8.7 0.9 0.1 0.3 1.4 0.1 1.4 0.1 6.7 0.1 2.3 0.9 1.7 4.3 0.1 0.0 0.0 0.4 0.1 0.3 1.8 1.4 1.1 1.5 2.5 0.3 0.1 0.1 9.3 0.1 2.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 2.0 1.8 3.5 1.8 1.8 3.2 1.7 3.1 1.4 2.2 2.8 1.2 0.3 0.0 0.0 12.7 0.6 0.3 1.2 1.4 0.0 15.9 0.6 0.6 1.0 2.8 7.2 0.0 0.0 0.2 3.7 0.0 0.0 17.1 0.2 0.7 3.5 1.4 41.9 0.4 54.4 0.4 0.2 4.2 4.6 0.8 11.4 0.6 0.0 0.2 0.3 3.3 57.2 0.1 0.0 0.8 3.2 0.6 3.1 0.8 0.0 1.9 0.5 2.7 7.2 62.8 2.2 1.4 1.6 9.1 0.9 6.6 0.0 0.1 3.4 3.5 0.0 3.6 2.4 1.4 9.2 0.1 0.0 0.3 1.7 0.5 0.3 8.7 RGS5 ENSG00000143248 "Regulator of G protein signaling 5" O15539 1 163111121-163321791 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Sertoli cells: 5114.5;Smooth muscle cells: 1592.3" "Cancer enhanced" "Detected in all" "renal cancer: 226.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 1303.0;OE19: 692.4;SH-SY5Y: 4234.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001821 Supported Supported Vesicles,Cytosol NA NA "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol Vesicles "HPA001821: AB_1079806" "unprognostic (3.75e-1)" "unprognostic (3.93e-3)" "unprognostic (2.31e-1)" "unprognostic (6.91e-2)" "unprognostic (2.50e-2)" "unprognostic (1.32e-3)" "unprognostic (1.65e-2)" "unprognostic (7.38e-2)" "unprognostic (3.54e-3)" "unprognostic (2.19e-1)" "unprognostic (1.53e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (9.17e-4)" "unprognostic (3.81e-3)" "unprognostic (7.05e-2)" "unprognostic (6.08e-2)" "unprognostic (1.41e-1)" 138.1 312.4 75.5 29.7 87.2 0.1 58.4 84.2 136.5 160.5 73.1 95.7 64.5 73.7 63.1 71.8 65.5 142.7 238.2 65.9 90.7 88.1 34.1 55.5 33.8 95.6 89.1 19.5 30.6 83.3 45.4 19.9 108.2 75.1 42.9 15.3 27.8 190.0 116.5 21.8 75.8 278.0 68.8 16.7 93.5 40.5 99.6 21.2 164.7 236.8 39.4 136.1 60.5 83.7 0.4 0.0 62.9 8.0 1.3 3.0 2.6 1.1 4.4 2.0 1.3 5.3 1.6 0.5 9.2 1.1 0.7 0.4 0.8 0.8 3.3 3.0 1.0 1.3 0.9 0.1 2.6 0.8 0.7 2.0 1.9 2.1 2.6 14.3 1303.0 0.3 0.2 1.2 4.7 0.0 0.9 2.2 38.7 692.4 1.4 0.4 0.1 3.6 0.7 0.0 5.2 4234.9 0.9 0.0 1.5 185.8 0.0 1.3 5.3 1.0 2.3 0.9 2.0 1.5 1.2 0.4 1.4 0.2 2.9 0.0 0.0 0.0 0.0 0.1 0.5 0.5 0.5 0.2 0.1 0.2 0.4 0.4 0.1 0.2 0.1 0.0 0.2 0.1 75.5 87.2 84.2 136.5 65.9 90.7 95.6 89.1 108.2 68.8 99.6 83.7 458.3 3.2 5.6 61.4 1.7 17.1 6.0 1.0 0.6 1.8 9.8 12.1 0.0 0.0 7.3 1.8 4.2 1.5 2.4 0.3 1.9 1.0 32.7 3.4 11.6 353.7 0.0 0.0 24.4 1.1 0.8 43.0 223.3 8.1 1.3 0.9 0.0 0.0 1.2 0.0 60.5 0.2 0.0 0.0 26.3 17.0 6.8 11.9 23.2 80.6 0.6 2.6 0.0 25.1 69.7 3.9 0.2 2.6 0.4 12.7 0.2 2.5 5.9 5.8 5114.5 44.9 1592.3 5.7 1.7 5.2 12.6 1.2 5.8 5.5 0.2 7.0 RGS6 ENSG00000182732 "Regulator of G protein signaling 6" P49758 14 71932429-72566530 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.2" "Cell type enhanced" "Detected in many" "Astrocytes: 97.3;Early spermatids: 173.5;Excitatory neurons: 652.7;Inhibitory neurons: 256.1;Late spermatids: 298.0" "Group enriched" "Detected in some" 7 "glioma: 3.1;thyroid cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HEL: 11.5;Karpas-707: 40.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003067 Uncertain Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Nucleoli, Vesicles" "HPA003067: AB_1079807" "unprognostic (7.18e-2)" "unprognostic (7.78e-2)" "unprognostic (1.00e-1)" "unprognostic (6.85e-2)" "unprognostic (5.61e-2)" "unprognostic (3.80e-2)" "unprognostic (1.24e-4)" "unprognostic (7.83e-2)" "unprognostic (2.03e-1)" "unprognostic (8.17e-2)" "unprognostic (1.30e-1)" "unprognostic (2.06e-2)" "unprognostic (8.64e-2)" "unprognostic (5.11e-2)" "unprognostic (8.06e-3)" "unprognostic (2.10e-1)" "unprognostic (3.68e-2)" 4.7 0.2 1.1 0.6 2.2 1.4 4.0 0.6 8.6 4.9 0.0 1.0 0.3 1.4 2.6 0.4 2.2 1.2 11.2 3.5 2.8 2.6 0.1 0.9 0.1 19.2 16.0 1.2 0.2 8.1 1.7 3.0 20.2 0.4 1.0 1.7 0.8 1.4 1.1 0.9 0.8 1.3 5.4 0.9 0.4 10.6 6.4 0.3 5.7 0.8 0.5 0.7 0.9 3.4 0.0 0.0 1.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 11.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 40.1 0.0 0.7 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.5 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.0 0.1 0.3 1.2 1.1 2.2 0.6 8.6 3.5 2.8 19.2 16.0 20.2 5.4 6.4 3.4 5.8 0.0 0.0 97.3 0.2 0.3 0.0 0.0 0.0 2.2 2.1 2.4 22.6 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 173.5 2.8 0.9 2.6 0.0 5.3 652.7 0.2 0.1 3.1 0.0 7.1 0.0 0.4 0.0 0.0 0.2 0.0 256.1 0.0 0.0 0.0 0.0 298.0 1.8 8.3 0.0 44.0 5.1 0.0 0.0 36.2 8.9 0.0 0.0 7.5 0.2 0.0 0.0 0.4 0.0 0.4 13.1 0.4 18.6 2.3 1.3 0.2 0.1 0.8 0.5 0.1 0.0 0.7 RGS9 "MGC111763, MGC26458, PERRS, RGS9L" ENSG00000108370 "Regulator of G protein signaling 9" O75916 17 65100812-65227703 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Sensory transduction, Vision" "Signal transduction inhibitor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.5" "Group enriched" "Detected in many" 6 "Cone photoreceptor cells: 325.2;Rod photoreceptor cells: 480.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "gdT-cell: 9.7;MAIT T-cell: 2.5;memory CD8 T-cell: 6.8;naive CD8 T-cell: 3.2;NK-cell: 4.0" "Group enriched" "Detected in many" 42 "NK-cells: 4.0;T-cells: 9.7" "Cell line enhanced" "Detected in some" "HDLM-2: 25.9;HEL: 11.7;hTERT-RPE1: 4.7;SuSa: 4.1" "Region enriched" "Detected in all" 9 "basal ganglia: 248.1" "Region enriched" "Detected in all" 10 "basal ganglia: 110.0" "HPA013550, HPA014137" Enhanced Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles" "HPA013550: , HPA014137: AB_2668943" "unprognostic (4.43e-3)" "unprognostic (7.49e-3)" "unprognostic (5.12e-2)" "unprognostic (3.09e-5)" "unprognostic (1.07e-1)" "unprognostic (1.14e-1)" "unprognostic (3.17e-1)" "unprognostic (1.93e-1)" "unprognostic (1.20e-1)" "unprognostic (4.88e-2)" "prognostic favorable (1.35e-4)" "unprognostic (1.07e-1)" "unprognostic (5.07e-2)" "unprognostic (4.94e-2)" "unprognostic (3.69e-1)" "unprognostic (1.51e-1)" "unprognostic (1.49e-1)" 0.8 1.5 6.2 1.2 23.5 0.2 0.8 4.3 9.4 1.6 3.8 8.5 1.1 1.7 2.5 1.5 10.3 1.0 0.8 5.1 9.3 2.4 2.3 5.1 2.1 5.3 5.9 2.6 1.4 5.5 12.1 1.2 6.9 4.6 1.3 1.3 1.3 3.3 0.1 1.4 3.8 1.4 5.2 1.7 3.8 0.4 7.4 0.6 0.6 0.3 3.0 2.9 2.8 4.6 0.4 0.0 1.3 0.1 0.1 0.2 0.0 0.1 2.6 0.0 0.3 0.2 0.0 1.2 1.8 0.0 0.0 0.1 0.0 0.1 0.1 25.9 0.6 11.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 4.7 0.0 0.1 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.3 0.0 0.0 0.2 4.1 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 9.7 0.0 2.5 0.0 0.8 6.8 0.0 0.0 0.0 3.2 0.1 4.0 0.0 0.1 0.0 1.7 6.2 23.5 4.3 9.4 5.1 9.3 5.3 5.9 6.9 5.2 7.4 4.6 1.3 3.2 1.5 33.3 0.4 0.4 1.4 0.9 0.6 25.0 7.8 14.5 0.4 0.0 1.3 1.8 325.2 0.0 27.5 0.1 3.9 8.9 0.6 2.5 1.8 2.6 59.7 0.0 2.3 3.1 0.1 5.8 1.1 4.2 0.0 3.3 1.1 0.0 0.1 52.2 2.3 2.3 0.0 0.0 3.0 2.4 0.9 2.9 1.8 1.9 19.4 39.2 18.6 2.5 1.2 2.7 0.1 4.9 6.3 0.1 0.1 14.2 0.8 480.2 0.0 0.5 1.9 0.1 0.4 0.0 0.1 0.1 10.3 12.8 0.6 0.3 RHBDF1 "C16orf8, Dist1, EGFR-RS, FLJ2235, iRhom1" ENSG00000007384 "Rhomboid 5 homolog 1" Q96CC6 16 58059-76355 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Growth factor binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 66.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077399 Uncertain Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA077399: " "unprognostic (2.62e-1)" "unprognostic (2.86e-2)" "unprognostic (4.76e-2)" "unprognostic (4.04e-2)" "unprognostic (1.51e-2)" "unprognostic (3.69e-2)" "unprognostic (5.60e-3)" "unprognostic (4.54e-3)" "unprognostic (4.51e-2)" "unprognostic (1.02e-1)" "unprognostic (7.81e-3)" "unprognostic (2.09e-1)" "prognostic unfavorable (2.49e-5)" "unprognostic (4.81e-2)" "unprognostic (1.87e-1)" "unprognostic (8.36e-2)" "unprognostic (4.22e-2)" 41.9 11.5 14.5 6.0 14.4 0.5 44.3 13.5 19.5 65.1 13.3 38.2 7.5 38.1 13.0 47.0 36.4 22.1 51.7 14.3 13.5 24.7 13.2 58.5 5.5 14.5 14.4 55.6 23.4 8.9 13.3 27.5 13.9 61.2 7.1 2.5 38.3 16.5 34.1 46.1 24.8 10.5 14.0 19.3 28.5 8.0 14.7 1.2 33.4 16.9 5.5 44.6 61.4 13.5 10.8 17.3 9.7 22.5 37.2 45.7 31.8 29.1 53.8 20.1 19.1 23.5 36.9 0.6 11.8 31.1 10.2 33.6 4.8 19.6 3.4 0.5 5.3 0.4 18.8 6.6 41.4 0.3 18.3 38.3 20.3 51.9 8.6 35.5 31.4 0.1 4.1 0.4 32.2 60.6 0.1 3.5 8.8 22.7 14.5 0.3 11.5 0.9 22.7 11.0 0.3 2.4 8.4 31.8 18.7 11.9 49.1 3.8 32.6 31.5 21.9 24.8 8.1 0.2 0.7 0.3 22.0 0.6 50.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.5 14.4 13.5 19.5 14.3 13.5 14.5 14.4 13.9 14.0 14.7 13.5 10.5 19.2 6.2 9.1 0.3 6.8 9.9 15.2 5.2 0.8 17.8 13.5 9.9 22.8 15.8 9.2 66.7 19.0 0.3 21.9 0.0 21.4 1.1 3.8 9.9 9.2 0.0 0.0 1.7 8.0 16.3 20.6 15.8 11.2 0.0 8.7 8.2 3.0 2.2 0.0 0.6 9.8 18.3 0.6 5.1 1.1 19.6 0.4 16.0 5.6 0.0 6.9 0.0 16.6 0.7 28.4 13.6 13.9 0.2 25.8 2.1 2.3 5.3 4.9 13.1 10.8 22.3 0.3 1.9 6.6 5.5 30.6 0.8 16.4 3.8 17.9 RHOBTB3 KIAA0878 ENSG00000164292 "Rho related BTB domain containing 3" O94955 5 95713522-95824383 "Predicted intracellular proteins" Transport Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Leydig cells: 397.3;Peritubular cells: 314.8;Skeletal myocytes: 347.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 7.3" "Group enriched" "Detected in many" 4 "granulocytes: 7.3;T-cells: 1.9" "Cell line enhanced" "Detected in many" "EFO-21: 250.6;HaCaT: 332.7;SuSa: 315.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000265 Uncertain Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 22: Non-specific - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA000265: " "unprognostic (1.68e-1)" "unprognostic (9.60e-2)" "unprognostic (5.62e-2)" "unprognostic (1.31e-3)" "unprognostic (1.84e-1)" "unprognostic (3.39e-2)" "unprognostic (7.37e-2)" "unprognostic (4.28e-1)" "unprognostic (6.00e-3)" "unprognostic (9.29e-2)" "unprognostic (9.15e-2)" "unprognostic (3.64e-1)" "unprognostic (1.56e-3)" "unprognostic (7.01e-3)" "unprognostic (1.15e-1)" "unprognostic (3.23e-1)" "unprognostic (8.21e-2)" 79.8 38.3 58.8 11.9 81.2 8.1 23.8 59.1 64.2 27.7 12.1 22.5 14.8 13.1 27.0 17.0 16.5 19.7 33.7 55.6 47.8 28.3 21.7 16.9 6.8 81.5 56.4 83.0 111.1 55.6 13.2 54.0 52.1 28.8 20.8 29.0 41.9 20.6 29.8 13.2 16.6 20.6 50.6 11.3 22.6 21.4 64.5 8.3 19.9 32.7 2.3 25.5 13.4 67.4 53.7 20.4 51.1 55.1 188.4 108.5 0.5 91.0 86.4 34.7 54.0 96.5 9.6 0.2 250.6 45.8 88.5 332.7 27.7 6.6 59.4 2.2 36.6 18.3 185.8 28.9 148.6 4.3 25.5 176.6 4.8 52.0 0.9 147.6 27.0 15.5 74.7 13.4 139.3 14.8 5.8 14.9 19.7 33.4 33.4 8.2 100.3 6.5 29.1 35.6 90.3 118.9 71.8 31.0 85.7 315.9 23.6 26.3 44.5 46.1 195.7 31.1 35.8 13.5 28.3 2.7 14.8 1.1 76.8 0.1 0.6 7.3 1.9 0.3 0.7 0.5 1.4 1.6 0.1 0.1 1.8 0.4 0.4 0.3 1.0 0.8 0.8 0.6 58.8 81.2 59.1 64.2 55.6 47.8 81.5 56.4 52.1 50.6 64.5 67.4 23.4 176.3 13.3 229.9 5.4 10.8 65.8 25.9 13.6 68.3 81.2 44.1 79.4 44.3 49.8 141.6 20.9 62.2 15.7 21.4 60.7 69.7 11.4 55.3 118.6 15.7 92.0 32.6 35.2 111.0 139.7 201.3 3.1 76.8 100.1 178.3 14.3 77.3 33.3 6.7 57.3 66.9 14.2 23.0 11.6 22.1 397.3 20.4 42.7 30.0 3.7 270.3 71.1 117.6 64.8 40.7 70.1 314.8 7.1 53.8 19.9 3.1 33.7 35.9 32.9 347.6 99.2 4.6 8.8 10.1 27.4 115.2 9.8 177.2 84.5 102.2 RHOH "ARHH, TTF" ENSG00000168421 "Ras homolog family member H" Q15669 4 40191053-40246967 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 62.9;lymphoid tissue: 98.2" "Cell type enhanced" "Detected in many" "B-cells: 273.0;dendritic cells: 90.5;granulocytes: 141.8;NK-cells: 64.9;Plasma cells: 183.1;T-cells: 223.6" "Cancer enhanced" "Detected in many" "breast cancer: 4.2" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 126.3;HMC-1: 92.5;JURKAT: 123.7;MOLT-4: 179.4;U-266/70: 65.5;U-266/84: 56.8;U-698: 116.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA030345, HPA061314" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus, Vesicles" "HPA030345: AB_10601607, HPA061314: " "unprognostic (4.00e-2)" "unprognostic (1.83e-4)" "unprognostic (1.24e-2)" "unprognostic (2.22e-5)" "unprognostic (1.35e-1)" "unprognostic (1.32e-3)" "unprognostic (1.16e-1)" "unprognostic (2.73e-2)" "unprognostic (2.30e-2)" "unprognostic (4.30e-2)" "unprognostic (9.07e-2)" "unprognostic (1.38e-1)" "unprognostic (3.31e-6)" "unprognostic (2.96e-1)" "unprognostic (3.91e-2)" "unprognostic (4.46e-2)" "unprognostic (2.44e-2)" 2.2 0.9 0.7 36.4 0.6 62.9 13.2 0.5 0.8 2.9 0.6 6.3 4.8 1.6 0.9 2.9 1.5 6.4 0.7 0.6 0.8 1.2 2.7 5.7 86.0 1.1 1.3 0.9 1.4 0.4 0.7 0.9 0.9 2.7 5.6 0.0 3.9 0.9 0.6 1.2 20.6 1.5 1.0 42.6 8.2 0.7 0.8 98.2 1.8 0.3 85.2 10.6 1.6 1.0 0.2 0.4 0.5 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 126.3 0.1 0.0 0.1 0.1 0.1 0.0 0.0 2.6 0.0 18.8 0.1 0.0 0.0 21.1 92.5 1.5 0.0 0.0 0.0 0.1 0.1 123.7 1.4 1.2 0.0 0.0 179.4 13.3 2.3 0.0 0.4 19.1 0.3 4.3 0.0 0.0 0.1 0.1 0.3 0.8 0.2 0.1 5.7 0.5 0.5 0.0 0.5 0.1 0.2 65.5 56.8 116.3 0.1 4.4 0.1 210.3 1.1 168.7 112.2 0.8 99.3 164.3 176.9 151.1 1.9 212.1 274.3 220.5 8.4 74.2 1.2 26.1 268.4 124.1 0.7 0.6 0.5 0.8 0.6 0.8 1.1 1.3 0.9 1.0 0.8 1.0 2.9 3.2 9.9 0.3 273.0 7.1 1.4 0.3 1.8 0.0 11.1 6.7 1.1 1.5 2.9 0.0 0.0 0.1 90.5 0.3 0.0 0.1 0.6 0.6 0.5 2.3 0.0 23.4 0.3 0.0 0.2 3.6 9.7 1.0 141.8 0.0 1.8 0.2 2.2 0.0 0.3 0.4 0.0 4.4 16.2 0.7 0.0 28.4 56.9 8.4 11.3 0.0 64.9 0.5 0.1 0.0 0.1 0.0 183.1 1.4 0.0 0.4 1.0 0.0 0.0 2.0 2.0 0.3 0.2 0.3 7.0 0.3 223.6 0.1 0.3 2.0 RHOQ "ARHQ, RASL7A, TC10" ENSG00000119729 "Ras homolog family member Q" P17081 2 46541806-46584688 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 189.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 1.5;classical monocyte: 2.5;eosinophil: 4.2;intermediate monocyte: 2.7;memory B-cell: 1.7;myeloid DC: 1.6;naive B-cell: 2.4;neutrophil: 4.8;non-classical monocyte: 1.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 164.0;ASC TERT1: 132.0;SK-MEL-30: 150.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044938 Approved Vesicles,Cytosol No No "Cluster 24: B-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Vesicles, Cytosol" "HPA044938: AB_2679149" "unprognostic (1.24e-1)" "unprognostic (1.30e-2)" "unprognostic (5.82e-2)" "unprognostic (2.07e-2)" "unprognostic (3.61e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (9.60e-5)" "unprognostic (2.01e-2)" "unprognostic (9.24e-2)" "unprognostic (2.11e-2)" "unprognostic (1.97e-1)" "unprognostic (5.43e-2)" "unprognostic (3.88e-3)" "unprognostic (1.39e-2)" "unprognostic (1.87e-1)" "unprognostic (7.68e-2)" "unprognostic (3.52e-2)" 96.9 35.7 34.8 30.1 40.1 12.4 64.8 38.9 41.4 59.6 43.9 67.0 11.0 53.2 67.7 18.9 59.3 26.7 196.8 34.3 44.7 44.3 22.6 56.0 23.8 40.9 44.2 40.8 28.6 50.4 29.5 28.6 38.9 50.6 13.5 27.7 32.7 36.5 162.4 28.1 35.3 38.4 39.2 42.7 32.8 10.1 36.8 9.9 39.1 181.3 19.1 62.8 44.7 43.5 12.3 12.4 21.0 28.6 164.0 132.0 3.7 32.8 84.1 16.2 24.4 6.2 4.1 28.7 34.0 58.5 52.4 5.8 20.6 9.8 29.3 10.2 15.3 8.2 9.8 20.9 81.8 8.8 10.7 118.1 17.3 20.1 22.5 39.0 19.3 3.1 12.1 44.0 35.2 8.1 6.9 17.9 20.8 8.9 14.4 5.3 34.5 10.1 23.1 22.4 15.3 50.3 11.6 16.4 150.8 32.9 9.0 20.7 13.2 50.1 44.8 49.3 14.1 48.5 17.7 28.4 73.6 22.1 18.4 1.5 2.5 4.2 0.4 2.7 0.3 1.7 0.2 0.4 1.6 2.4 0.0 0.3 4.8 0.3 1.9 0.6 0.3 0.7 34.8 40.1 38.9 41.4 34.3 44.7 40.9 44.2 38.9 39.2 36.8 43.5 27.9 57.7 22.4 65.3 38.1 22.4 31.0 18.1 11.4 21.1 30.4 22.4 189.2 14.3 22.1 20.2 10.4 14.6 32.2 1.0 17.6 21.4 30.8 22.1 90.2 23.4 6.0 2.1 12.8 32.0 3.6 82.8 4.1 24.6 12.0 12.1 17.5 12.2 44.5 121.1 27.7 5.5 8.2 90.9 77.8 11.4 35.4 90.7 42.7 68.4 55.1 52.9 15.5 52.3 41.5 22.4 0.3 42.5 42.0 41.2 0.2 30.1 18.8 24.2 46.0 54.2 82.3 2.3 4.5 6.8 19.7 25.9 17.0 10.9 1.9 31.9 RIMBP3 "KIAA1666, RIMBP3.1, RIMBP3A" ENSG00000275793 "RIMS binding protein 3" Q9UFD9 22 18605815-18611919 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 27 "brain: 35.7;choroid plexus: 24.5;testis: 28.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MOLT-4: 3.0;THP-1: 3.2" HPA001183 Supported Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 30: Non-specific - Translation" "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "HPA001183: AB_1079205" "unprognostic (1.55e-2)" "unprognostic (3.95e-3)" "unprognostic (1.62e-1)" "unprognostic (3.95e-2)" "unprognostic (2.29e-2)" "unprognostic (9.81e-3)" "unprognostic (1.83e-3)" "unprognostic (1.84e-1)" "unprognostic (2.71e-1)" "unprognostic (4.72e-3)" "unprognostic (6.06e-3)" "unprognostic (9.58e-2)" "unprognostic (8.49e-3)" "unprognostic (7.23e-2)" "unprognostic (1.03e-1)" "unprognostic (2.69e-3)" "unprognostic (7.95e-2)" 0.1 0.2 7.9 0.4 10.8 0.1 0.0 35.7 22.0 0.1 24.5 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.0 11.0 11.7 0.0 0.0 0.2 0.8 14.9 10.1 0.1 0.1 0.3 0.1 0.2 26.2 0.2 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.0 19.6 0.7 0.2 28.4 13.5 1.0 0.4 0.0 0.5 0.0 0.0 32.4 0.4 1.3 0.5 0.4 0.7 0.3 0.0 0.5 1.4 0.6 0.7 0.0 0.0 0.3 0.6 0.2 0.4 0.3 0.3 0.0 0.1 1.4 0.4 0.6 0.3 0.5 0.0 2.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 1.1 0.2 0.3 0.5 0.6 3.0 1.7 0.6 0.6 0.1 1.2 1.6 0.2 0.1 0.1 0.8 0.1 1.2 0.0 0.2 0.1 0.1 3.2 0.1 1.0 0.7 0.5 0.3 0.0 0.4 0.3 0.5 0.7 1.1 0.0 0.2 0.2 0.1 0.1 0.4 0.1 0.2 0.2 0.2 0.1 0.3 0.2 0.1 0.3 0.0 0.0 0.2 0.3 7.9 10.8 35.7 22.0 11.0 11.7 14.9 10.1 26.2 19.6 13.5 32.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RIMBP3B ENSG00000274600 "RIMS binding protein 3B" A6NNM3 22 21383374-21389478 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 49 "brain: 41.3;choroid plexus: 18.4;testis: 13.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.2;RH-30: 1.1;THP-1: 2.1" HPA001183 Supported Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "Vesicles, Plasma membrane" "HPA001183: AB_1079205" "unprognostic (3.78e-1)" "unprognostic (3.54e-2)" "unprognostic (1.53e-2)" "unprognostic (1.51e-1)" "unprognostic (3.28e-1)" "unprognostic (5.35e-2)" "unprognostic (4.37e-1)" "unprognostic (3.61e-4)" "unprognostic (1.69e-2)" "unprognostic (7.11e-2)" 0.0 0.1 8.2 0.4 12.8 0.0 0.0 41.3 19.1 0.0 18.4 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 10.4 13.6 0.0 0.0 0.1 0.3 16.5 12.6 0.0 0.1 0.2 0.0 0.2 19.2 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 16.2 0.2 0.0 13.6 13.2 0.4 0.1 0.0 0.2 0.0 0.0 29.6 0.0 0.5 0.1 0.1 0.3 0.2 0.1 0.1 0.4 0.2 0.2 0.0 0.1 0.1 0.6 0.0 0.1 0.0 0.2 0.0 0.0 0.7 0.3 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.2 0.2 0.9 1.2 0.1 0.2 0.1 0.8 1.1 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.2 0.0 0.0 2.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.3 0.2 0.6 0.0 0.1 0.1 0.1 0.0 0.2 0.0 0.1 0.2 0.1 0.0 0.2 0.1 0.0 0.2 0.1 0.0 0.2 0.1 8.2 12.8 41.3 19.1 10.4 13.6 16.5 12.6 19.2 16.2 13.2 29.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RIMBP3C ENSG00000183246 "RIMS binding protein 3C" A6NJZ7 22 21545678-21551461 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 21 "testis: 6.1" "Cell type enhanced" "Detected in some" "Early spermatids: 30.7;Late spermatids: 49.4;Spermatocytes: 11.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA001183 Supported Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "HPA001183: AB_1079205" "unprognostic (1.74e-1)" "unprognostic (4.05e-2)" "unprognostic (3.49e-2)" "unprognostic (2.18e-1)" "unprognostic (8.30e-2)" "unprognostic (4.53e-2)" "unprognostic (6.65e-2)" "unprognostic (1.15e-3)" "unprognostic (6.23e-2)" "unprognostic (2.17e-6)" "unprognostic (3.04e-1)" "unprognostic (3.29e-1)" "unprognostic (3.76e-6)" "unprognostic (1.66e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 49.4 0.6 0.1 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 RINL FLJ45909 ENSG00000187994 "Ras and Rab interactor like" Q6ZS11 19 38867830-38878275 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 32.5;NK-cells: 45.3;Skeletal myocytes: 30.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 14.2;Karpas-707: 24.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA042083, HPA042103" Uncertain Approved Nucleoplasm,Vesicles No No "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Vesicles" "HPA042083: AB_10793977, HPA042103: AB_10797380" "unprognostic (1.30e-1)" "prognostic favorable (6.49e-5)" "unprognostic (7.38e-2)" "unprognostic (1.75e-2)" "unprognostic (6.05e-2)" "prognostic favorable (1.64e-4)" "unprognostic (2.61e-2)" "unprognostic (3.64e-2)" "unprognostic (4.87e-2)" "unprognostic (5.95e-2)" "unprognostic (1.85e-1)" "unprognostic (7.90e-2)" "unprognostic (3.18e-1)" "unprognostic (1.75e-1)" "unprognostic (1.89e-1)" "unprognostic (3.17e-2)" "unprognostic (6.40e-3)" 5.3 2.5 2.2 5.3 2.7 2.8 4.2 2.6 2.8 2.8 2.9 3.9 1.6 2.0 0.9 6.3 3.3 1.7 3.5 2.1 2.3 6.1 7.8 4.3 9.7 2.6 2.1 1.5 13.2 2.7 7.2 1.6 2.9 2.5 1.4 2.5 5.3 1.1 2.3 3.6 8.4 1.0 1.9 15.8 4.2 1.1 2.2 3.9 5.1 0.9 7.6 4.6 3.7 2.2 0.0 1.8 0.4 0.2 0.7 0.3 2.8 0.4 0.3 0.4 0.4 1.9 9.2 9.1 3.1 0.4 0.1 0.2 1.7 2.4 0.5 1.7 0.6 10.1 2.6 4.8 1.9 6.4 14.2 2.0 0.4 1.2 0.5 0.3 3.5 5.1 1.8 24.6 0.0 1.6 1.6 4.3 0.8 5.2 0.3 1.2 0.1 6.5 1.7 0.2 3.2 1.3 4.2 6.7 3.6 0.4 0.8 7.7 2.6 0.1 1.9 0.5 0.1 9.1 9.3 6.3 0.7 2.8 0.5 5.3 1.1 1.6 10.3 2.5 6.5 17.4 6.9 7.7 2.0 21.9 5.3 6.4 3.0 5.2 2.5 16.0 8.1 3.6 2.2 2.7 2.6 2.8 2.1 2.3 2.6 2.1 2.9 1.9 2.2 2.2 6.7 3.2 7.7 0.0 22.4 3.2 5.3 2.9 4.6 4.0 5.8 4.7 3.5 8.6 2.3 3.7 8.4 13.9 32.5 0.6 7.9 7.3 0.5 2.8 1.6 6.9 7.2 9.0 2.2 7.3 7.1 4.3 5.1 6.3 15.2 1.3 8.2 7.5 9.3 0.0 1.6 0.7 14.2 6.8 2.7 1.3 3.1 4.3 10.6 1.0 10.5 6.2 45.3 3.5 0.6 5.1 1.7 2.6 14.8 2.3 0.6 12.7 1.3 10.6 0.0 30.3 2.3 2.7 4.4 6.4 3.8 4.1 24.6 5.0 1.3 3.6 RNASE1 "RAC1, RNS1" ENSG00000129538 "Ribonuclease A family member 1, pancreatic" P07998 14 20801228-20802855 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Endonuclease, Hydrolase, Lyase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "pancreas: 9121.6" "Cell type enhanced" "Detected in many" "Adipocytes: 826.6;Alveolar cells type 1: 929.5;Alveolar cells type 2: 818.4;Gastric mucus-secreting cells: 821.1;Hepatic stellate cells: 650.3;Hofbauer cells: 1583.4;Intestinal goblet cells: 663.8;Macrophages: 632.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 9.7;myeloid DC: 20.3" "Group enriched" "Detected in many" 9 "dendritic cells: 20.3;monocytes: 9.7" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 286.8;OE19: 67.4;RT4: 114.2;TIME: 179.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001140 Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" NA NA 1100000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Vesicles Nucleoplasm "HPA001140: AB_1079816" "unprognostic (2.32e-2)" "unprognostic (3.16e-2)" "unprognostic (9.51e-3)" "unprognostic (7.77e-2)" "unprognostic (6.93e-2)" "unprognostic (1.28e-1)" "unprognostic (3.42e-3)" "unprognostic (6.59e-3)" "unprognostic (4.69e-2)" "unprognostic (7.92e-2)" "unprognostic (6.32e-2)" "unprognostic (3.56e-2)" "unprognostic (5.14e-3)" "unprognostic (1.11e-2)" "unprognostic (1.47e-1)" "unprognostic (2.43e-2)" "unprognostic (1.67e-1)" 694.2 501.3 336.6 131.3 466.1 6.2 353.3 404.4 556.1 203.9 294.9 378.4 176.7 139.4 112.0 194.0 232.0 406.4 377.7 351.3 380.9 253.0 54.5 775.9 187.8 438.9 408.3 190.6 9121.6 60.6 43.9 897.4 403.7 83.9 425.2 3.1 168.0 149.7 127.6 118.1 201.8 285.6 357.3 353.1 1003.5 977.5 465.4 177.6 119.7 280.6 68.8 374.7 107.9 533.7 0.0 1.4 0.5 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 6.7 0.0 0.3 1.7 0.0 2.2 0.6 0.0 1.4 0.0 0.1 0.1 5.3 0.1 0.8 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 286.8 0.0 31.4 0.4 0.0 0.0 0.3 2.0 1.2 67.4 0.0 0.2 0.1 1.5 0.2 114.2 1.2 1.4 0.0 0.8 0.3 2.0 0.3 0.1 179.3 0.0 2.7 1.8 0.3 0.6 0.1 0.1 4.6 0.1 3.8 1.6 9.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 20.3 0.1 0.0 0.0 0.1 0.0 0.0 5.0 0.0 2.4 336.6 466.1 404.4 556.1 351.3 380.9 438.9 408.3 403.7 357.3 465.4 533.7 826.6 929.5 818.4 1.6 11.1 35.6 1.0 1.9 15.9 0.1 6.2 11.7 59.8 27.1 174.0 16.5 0.0 12.9 5.7 261.8 0.0 8.8 20.0 3.8 1.9 581.7 48.7 28.0 0.5 315.2 14.6 58.4 821.1 3.4 25.2 103.8 650.3 7.9 1583.4 1.7 0.8 663.8 8.2 267.9 197.5 57.1 32.0 632.8 40.9 36.5 3.4 0.8 0.0 1.0 232.3 286.8 246.7 10.9 7.5 1.4 81.7 0.9 34.9 2.7 98.6 20.7 31.4 16.4 6.6 16.6 28.1 25.9 10.6 392.8 162.9 3.8 RND1 "ARHS, Rho6, RHOS" ENSG00000172602 "Rho family GTPase 1" Q92730 12 48857145-48865870 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 131.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 205.5;Ductal cells: 220.6;Exocrine glandular cells: 147.1;Pancreatic endocrine cells: 350.9" "Cancer enhanced" "Detected in many" "liver cancer: 16.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "SK-BR-3: 67.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077800 Supported "Vesicles,Plasma membrane,Actin filaments" NA NA "Cluster 30: Non-specific - Translation" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "Vesicles, Plasma membrane, Actin filaments" "HPA077800: AB_2686854" "unprognostic (5.60e-2)" "unprognostic (3.21e-2)" "unprognostic (2.23e-1)" "unprognostic (1.16e-1)" "unprognostic (6.90e-2)" "unprognostic (1.32e-3)" "unprognostic (3.59e-2)" "unprognostic (7.43e-2)" "unprognostic (2.21e-3)" "unprognostic (2.97e-1)" "unprognostic (1.93e-1)" "unprognostic (1.66e-1)" "unprognostic (3.89e-1)" "unprognostic (8.38e-3)" "unprognostic (6.18e-2)" "unprognostic (6.60e-2)" "unprognostic (3.35e-3)" 9.6 0.8 24.4 2.6 26.9 1.8 5.6 18.9 40.6 1.6 15.4 4.8 2.4 3.9 1.0 3.1 2.7 14.5 7.3 26.8 20.4 4.4 131.8 37.9 1.0 21.4 23.6 1.2 2.8 2.4 8.0 1.2 21.9 6.5 1.9 1.7 3.9 0.8 1.0 1.6 2.6 2.4 19.9 0.8 23.4 0.9 22.1 2.4 15.4 0.6 2.3 14.0 2.7 23.2 1.1 7.9 3.8 2.0 0.8 0.0 0.6 0.0 0.4 1.2 1.3 4.9 1.7 6.0 1.4 0.0 0.4 0.1 3.1 0.3 0.7 1.8 1.9 0.8 0.0 3.0 0.4 1.8 1.1 0.0 0.2 0.6 0.8 0.0 2.0 3.9 0.2 6.0 0.0 10.2 0.9 0.5 8.9 13.6 0.5 1.9 0.4 2.6 1.1 1.5 0.0 1.0 0.2 67.7 0.3 9.1 6.9 0.4 0.2 0.0 0.7 0.0 0.9 2.9 5.4 10.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 24.4 26.9 18.9 40.6 26.8 20.4 21.4 23.6 21.9 19.9 22.1 23.2 28.9 28.9 205.5 5.9 8.5 11.5 8.4 14.1 9.1 2.5 37.5 25.4 3.8 18.6 27.5 1.8 8.4 1.1 9.0 21.7 0.0 220.6 0.4 4.5 2.0 87.3 31.5 2.7 10.6 147.1 0.7 10.5 55.5 12.6 15.2 0.8 6.1 10.9 1.2 0.0 2.7 11.4 18.3 0.8 24.1 0.0 0.0 6.6 14.2 1.0 6.4 3.0 0.0 7.1 1.0 350.9 42.2 0.4 6.5 19.5 11.1 1.7 7.7 3.6 0.0 5.8 16.7 0.8 1.6 4.3 10.5 1.5 9.9 0.6 5.4 8.6 RNF121 FLJ11099 ENSG00000137522 "Ring finger protein 121" Q9H920 11 71929018-71997597 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046041 Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA046041: AB_10965850" "unprognostic (1.36e-2)" "unprognostic (8.84e-2)" "unprognostic (9.72e-2)" "unprognostic (1.16e-1)" "unprognostic (2.64e-1)" "unprognostic (1.38e-2)" "unprognostic (1.41e-2)" "unprognostic (3.73e-2)" "unprognostic (1.22e-1)" "unprognostic (6.54e-2)" "unprognostic (1.85e-2)" "unprognostic (1.90e-1)" "prognostic favorable (2.72e-6)" "unprognostic (1.54e-1)" "unprognostic (1.81e-1)" "unprognostic (2.57e-2)" "unprognostic (1.70e-1)" 7.2 9.5 8.8 6.6 8.7 5.8 11.3 8.5 9.2 9.8 9.7 8.1 15.9 8.4 20.0 7.4 11.6 7.8 10.0 8.8 9.0 16.4 11.5 7.6 8.1 8.8 9.1 11.2 10.9 24.3 9.5 11.1 8.8 10.6 10.3 15.7 15.1 13.6 17.2 8.3 13.9 11.8 9.0 6.7 9.2 8.7 9.1 7.7 12.9 14.9 10.4 9.1 7.1 8.7 10.9 22.7 20.5 14.6 19.1 15.2 13.8 16.7 17.7 25.4 26.9 46.0 20.9 9.2 14.9 18.5 26.7 22.1 22.7 21.2 26.7 13.8 13.1 14.0 21.5 21.9 14.3 12.8 11.5 14.8 17.9 28.7 18.2 27.9 46.7 13.5 23.2 8.6 22.7 23.5 9.0 14.1 13.7 43.4 21.9 11.0 44.5 7.9 28.3 18.4 13.7 14.6 22.9 20.4 30.4 20.6 22.5 9.5 32.8 19.0 17.2 11.8 14.6 9.6 10.2 9.4 16.5 8.3 17.1 4.4 2.2 2.2 3.0 2.9 3.5 3.2 2.3 2.4 2.3 1.3 2.7 2.9 1.2 3.2 2.1 3.7 2.1 2.9 8.8 8.7 8.5 9.2 8.8 9.0 8.8 9.1 8.8 9.0 9.1 8.7 9.6 6.4 9.6 12.7 9.4 8.8 11.2 22.8 10.2 16.1 12.1 10.9 9.7 12.8 13.3 20.2 20.9 32.0 17.9 15.2 7.9 26.0 6.3 8.9 10.3 6.5 9.6 13.0 19.3 32.3 26.5 11.8 9.2 10.9 7.0 11.6 8.9 14.4 14.2 10.1 16.9 13.2 26.4 6.6 12.9 3.0 13.1 7.6 10.6 15.0 15.0 19.0 10.3 18.1 19.0 29.0 11.0 12.4 17.1 10.3 31.0 20.9 10.3 21.1 19.7 10.0 14.2 25.1 19.6 6.4 5.8 31.1 10.0 13.4 9.4 9.9 RNF13 RZF ENSG00000082996 "Ring finger protein 13" O43567 3 149812770-149962139 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 591.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 462.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064784 Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" Cytosol "HPA064784: AB_2685350" "unprognostic (1.27e-1)" "unprognostic (2.32e-2)" "unprognostic (1.03e-1)" "unprognostic (1.93e-2)" "unprognostic (1.80e-1)" "unprognostic (9.64e-2)" "unprognostic (8.49e-2)" "unprognostic (4.36e-3)" "unprognostic (1.72e-1)" "unprognostic (1.25e-1)" "unprognostic (6.94e-3)" "unprognostic (1.13e-1)" "prognostic favorable (2.00e-8)" "unprognostic (2.95e-1)" "unprognostic (4.11e-2)" "unprognostic (2.17e-1)" "unprognostic (1.79e-1)" 48.2 41.2 58.1 40.4 95.2 19.9 53.9 88.1 91.5 33.6 63.7 35.0 28.9 33.3 57.2 32.6 30.2 40.6 34.4 55.0 77.3 67.9 73.8 64.1 38.0 101.8 83.9 35.6 36.1 52.3 18.3 64.1 100.8 46.6 37.1 40.4 75.5 39.3 36.5 32.5 30.5 36.9 85.6 53.0 34.3 25.2 75.9 32.0 64.0 42.6 33.2 42.3 28.9 131.0 60.6 39.4 24.4 29.0 92.2 55.2 40.3 32.2 86.2 32.3 47.4 33.4 84.4 26.6 48.7 42.0 58.7 58.0 37.5 41.5 42.9 34.1 24.6 35.8 17.3 31.2 61.5 35.0 41.8 59.9 73.1 26.5 71.8 37.3 37.0 24.9 10.1 49.7 28.0 34.5 26.2 18.8 16.8 58.6 29.1 19.0 26.7 108.5 54.2 29.6 12.6 37.6 28.5 39.9 110.3 19.2 79.2 34.0 37.8 40.8 16.5 45.6 23.4 89.9 61.9 51.5 35.9 30.1 23.6 98.2 130.1 106.5 37.4 153.8 48.8 51.9 41.5 44.8 93.1 48.4 38.0 42.4 462.3 46.3 207.8 68.3 48.7 104.5 58.1 95.2 88.1 91.5 55.0 77.3 101.8 83.9 100.8 85.6 75.9 131.0 100.9 109.0 72.3 78.7 55.3 73.5 68.2 84.3 74.0 44.5 54.5 51.1 27.3 48.6 68.1 47.8 29.2 101.2 61.9 30.2 43.0 63.0 2.5 32.5 34.5 69.4 20.3 32.4 122.1 70.6 83.5 84.8 31.6 39.7 60.8 14.6 80.3 53.7 201.2 21.9 98.8 27.7 67.1 183.9 173.7 6.7 76.1 177.6 103.2 92.8 93.5 98.5 38.1 115.6 591.2 58.7 33.6 88.0 62.4 71.9 38.5 71.5 40.4 37.2 92.1 76.3 55.5 23.6 32.5 52.3 72.5 52.5 49.8 38.2 27.7 55.8 RNF135 MGC13061 ENSG00000181481 "Ring finger protein 135" Q8IUD6 17 30970984-30999911 "Enzymes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 73.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTCEpi: 63.3" "Low region specificity" "Detected in all" "HPA021576, HPA052404" Approved Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA021576: AB_1856331, HPA052404: AB_2681817" "unprognostic (1.13e-1)" "unprognostic (1.87e-2)" "unprognostic (6.24e-2)" "unprognostic (2.33e-2)" "unprognostic (2.68e-2)" "unprognostic (3.51e-3)" "unprognostic (1.57e-1)" "unprognostic (1.24e-1)" "unprognostic (4.60e-2)" "unprognostic (4.16e-1)" "unprognostic (1.35e-2)" "unprognostic (2.06e-1)" "prognostic unfavorable (7.51e-5)" "unprognostic (6.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.42e-1)" "unprognostic (4.47e-1)" 20.9 12.9 11.1 13.5 12.5 11.6 18.6 11.2 14.2 16.0 15.1 17.5 13.6 13.3 16.5 22.4 15.7 9.6 8.5 10.4 11.3 21.6 8.6 15.5 13.9 13.9 13.2 12.6 13.5 16.8 5.6 18.1 12.4 14.0 18.0 2.3 15.2 15.2 7.4 26.2 13.9 13.7 12.8 25.8 11.9 5.1 16.4 7.9 15.8 10.1 12.6 14.8 17.3 13.8 12.7 25.6 1.5 25.4 34.0 28.5 22.7 9.7 14.9 9.4 8.4 0.0 9.4 11.5 14.8 19.0 17.0 17.0 13.2 12.1 7.8 10.0 5.6 4.8 8.1 0.0 24.3 12.8 10.7 27.7 63.3 10.1 33.5 16.1 15.8 0.0 0.0 34.9 15.6 17.0 0.1 13.5 10.5 25.7 14.4 27.9 0.0 39.2 13.6 18.2 9.8 0.5 14.9 5.9 14.9 16.6 39.4 20.2 13.3 0.0 3.5 15.6 11.5 0.4 1.3 7.3 16.5 22.1 13.3 25.3 61.6 31.3 12.8 57.3 7.2 28.4 6.8 6.8 46.4 28.4 3.7 6.2 54.0 13.9 70.2 17.1 10.1 29.2 11.1 12.5 11.2 14.2 10.4 11.3 13.9 13.2 12.4 12.8 16.4 13.8 14.1 3.2 5.9 7.8 14.1 9.3 13.4 16.8 22.2 0.1 13.1 15.0 4.0 7.2 7.8 11.0 0.0 47.5 10.5 23.4 29.4 9.9 0.4 14.5 12.8 13.2 4.9 11.2 0.8 18.6 37.1 13.2 5.6 12.4 1.3 14.1 25.4 2.7 51.1 0.0 1.0 12.0 8.2 73.9 8.4 1.6 16.8 35.5 16.0 26.2 45.3 3.9 19.6 9.0 0.7 11.9 13.1 15.4 9.0 22.2 27.5 49.3 10.4 0.6 26.3 8.2 14.2 0.7 4.0 24.1 14.6 43.6 7.5 10.6 14.6 11.2 RNF144A "hUIP4, KIAA0161, RNF144, UBCE7IP4" ENSG00000151692 "Ring finger protein 144A" P50876 2 6917412-7068286 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 73.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 176.6;Inhibitory neurons: 101.7;Oligodendrocyte precursor cells: 194.5;Oligodendrocytes: 330.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 6.1" "Group enriched" "Detected in many" 7 "granulocytes: 6.1;T-cells: 2.4" "Cell line enhanced" "Detected in many" "HEL: 39.7;HMC-1: 127.9;SH-SY5Y: 39.0;SK-MEL-30: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049939 Approved Supported Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA049939: AB_2680960" "unprognostic (1.78e-1)" "unprognostic (2.53e-3)" "unprognostic (8.37e-2)" "prognostic unfavorable (6.00e-4)" "unprognostic (6.57e-2)" "prognostic favorable (6.96e-4)" "unprognostic (7.04e-6)" "unprognostic (1.20e-1)" "unprognostic (2.03e-2)" "unprognostic (5.64e-1)" "unprognostic (9.11e-2)" "unprognostic (1.92e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (7.32e-5)" "unprognostic (1.30e-2)" "unprognostic (3.01e-1)" "unprognostic (1.82e-3)" 9.7 28.5 21.1 4.1 46.1 13.9 10.1 59.2 36.7 24.2 1.2 5.7 2.6 26.3 7.7 4.3 7.8 7.1 8.1 17.5 24.0 7.3 1.3 5.4 6.0 30.1 27.0 19.3 30.7 38.1 12.9 5.9 33.4 9.1 5.3 23.0 4.6 6.4 9.6 5.4 3.8 11.6 21.5 23.0 2.6 4.7 30.3 7.5 3.4 10.1 5.6 4.4 7.5 73.6 0.8 5.8 30.1 6.2 6.6 13.6 23.0 0.2 0.0 1.1 2.8 0.1 0.7 2.9 3.3 0.3 8.7 0.7 10.0 0.0 0.0 1.6 2.6 39.7 0.3 11.8 0.3 0.7 127.9 21.7 0.1 2.2 0.0 0.0 0.0 9.9 17.3 0.6 0.0 4.9 20.6 1.7 11.0 0.7 13.6 15.9 21.8 2.6 1.0 10.2 9.9 39.0 0.5 4.0 39.8 3.9 1.7 2.6 0.1 3.9 10.0 10.7 4.5 10.4 3.5 0.1 14.7 8.7 14.3 1.3 0.0 6.1 1.2 0.0 1.8 0.0 1.3 0.9 0.1 0.1 2.4 1.7 0.3 0.5 0.0 0.0 0.6 0.4 21.1 46.1 59.2 36.7 17.5 24.0 30.1 27.0 33.4 21.5 30.3 73.6 27.8 3.2 4.2 34.3 2.4 2.4 0.7 0.0 1.8 4.6 2.5 2.5 11.5 2.8 1.9 0.0 75.0 2.4 5.3 15.4 1.9 3.3 5.5 6.1 15.4 13.9 25.4 18.5 176.6 5.8 3.1 10.4 2.6 10.7 8.9 31.5 23.2 1.1 4.9 10.1 101.7 2.7 0.0 1.0 1.7 14.2 4.4 1.7 24.9 17.8 1.2 7.6 10.3 194.5 330.3 3.0 11.1 10.5 3.1 3.0 2.0 0.3 1.5 39.8 0.0 16.1 5.2 1.8 6.6 5.2 1.6 1.1 9.8 19.1 2.7 1.7 RNF149 FLJ90504 ENSG00000163162 "Ring finger protein 149" Q8NC42 2 101271219-101308701 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Kupffer cells: 278.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 619.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 619.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011424 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Plasma membrane" "HPA011424: AB_1079825" "unprognostic (2.56e-2)" "unprognostic (4.70e-2)" "unprognostic (1.96e-1)" "unprognostic (3.49e-2)" "unprognostic (3.17e-2)" "unprognostic (5.17e-3)" "unprognostic (4.16e-2)" "unprognostic (4.77e-3)" "unprognostic (5.61e-2)" "unprognostic (1.43e-2)" "unprognostic (5.69e-3)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.04e-8)" "unprognostic (1.39e-1)" "unprognostic (6.16e-2)" "unprognostic (2.70e-1)" "prognostic favorable (2.91e-4)" 26.7 15.2 7.7 40.3 7.5 52.3 16.3 7.7 9.7 17.7 12.3 15.7 16.8 12.4 16.3 35.5 16.9 18.9 12.5 7.6 8.9 16.3 26.6 30.5 18.3 9.9 8.5 15.9 22.3 17.9 10.4 21.8 9.6 12.6 15.8 7.8 18.3 10.1 8.5 25.6 18.2 12.9 8.5 53.1 19.1 15.8 9.1 15.2 12.2 9.4 19.6 29.1 22.7 10.9 19.9 11.4 8.8 11.3 31.6 31.3 49.7 24.0 31.8 32.1 35.8 29.0 51.6 6.1 28.3 23.9 42.9 39.0 12.5 24.6 29.7 16.9 16.6 12.4 9.9 50.0 42.1 13.4 19.2 28.9 40.0 37.9 25.1 24.7 58.9 13.0 10.7 18.0 32.4 16.9 18.8 14.0 6.1 27.1 20.0 11.5 14.2 23.4 38.0 48.0 11.5 8.5 14.4 36.0 37.2 9.5 9.7 17.8 39.6 16.2 9.1 24.5 5.3 35.5 22.5 0.2 5.2 18.6 12.2 44.0 73.6 90.3 43.8 118.1 41.8 13.2 40.0 45.3 27.9 8.5 28.2 30.2 619.9 15.3 134.1 52.5 53.8 69.8 7.7 7.5 7.7 9.7 7.6 8.9 9.9 8.5 9.6 8.5 9.1 10.9 19.9 48.1 48.1 44.7 55.2 76.9 78.1 63.5 54.7 20.4 29.7 15.9 13.0 41.5 48.4 55.2 56.3 65.2 112.4 53.1 1.9 59.1 97.9 41.8 31.9 30.0 8.5 22.7 82.8 42.2 73.0 53.5 37.2 63.1 39.2 17.3 27.1 46.2 85.9 8.4 71.6 31.7 12.2 278.6 144.2 37.2 30.7 209.0 40.9 50.6 116.5 11.6 61.8 34.7 59.6 54.3 52.3 19.5 125.5 73.5 45.9 25.8 44.8 20.7 59.2 40.5 30.1 36.6 40.3 128.3 91.6 128.1 115.7 23.8 32.8 154.1 RNF151 ENSG00000179580 "Ring finger protein 151" Q2KHN1 16 1966823-1968975 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 411 "testis: 190.2" "Group enriched" "Detected in some" 137 "Early spermatids: 2202.5;Late spermatids: 1521.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055054 Approved "Nuclear speckles,Vesicles,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" Cytosol "Nuclear speckles, Vesicles" "HPA055054: " "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "unprognostic (2.54e-2)" "unprognostic (1.18e-1)" "unprognostic (5.65e-2)" "unprognostic (4.01e-3)" "unprognostic (1.15e-1)" "unprognostic (1.22e-1)" "unprognostic (1.41e-1)" "unprognostic (3.20e-1)" "unprognostic (4.39e-3)" "unprognostic (4.63e-1)" "unprognostic (1.98e-4)" "unprognostic (1.46e-1)" "unprognostic (4.19e-2)" "unprognostic (1.10e-1)" "unprognostic (2.43e-2)" 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 190.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.1 0.4 0.4 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.2 0.1 0.2 0.0 0.2 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.3 0.1 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2202.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1521.4 9.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.1 0.0 0.0 6.6 0.2 0.1 13.5 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 RNF157 KIAA1917 ENSG00000141576 "Ring finger protein 157" Q96PX1 17 76142465-76240493 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 86.9;retina: 59.0;skeletal muscle: 73.9;testis: 31.4;tongue: 43.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 114.1;Cone photoreceptor cells: 189.7;Excitatory neurons: 64.6;Horizontal cells: 180.0;Inhibitory neurons: 92.7;Rod photoreceptor cells: 70.9" "Cancer enhanced" "Detected in many" "glioma: 11.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 2.2;T-cells: 5.8" "Cell line enhanced" "Detected in many" "HDLM-2: 100.9;U-266/70: 50.6;U-266/84: 45.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021854, HPA021991, HPA023922" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "Golgi apparatus" Vesicles "HPA021854: AB_10600307, HPA021991: AB_10601112, HPA023922: AB_10602202" "unprognostic (4.21e-1)" "unprognostic (4.62e-2)" "unprognostic (1.55e-2)" "unprognostic (2.63e-3)" "unprognostic (4.93e-2)" "unprognostic (5.06e-2)" "unprognostic (2.07e-3)" "unprognostic (4.21e-1)" "unprognostic (1.07e-1)" "unprognostic (2.35e-2)" "unprognostic (1.04e-3)" "unprognostic (4.02e-1)" "unprognostic (8.26e-2)" "unprognostic (8.69e-3)" "unprognostic (2.28e-1)" "unprognostic (2.75e-2)" "unprognostic (1.38e-1)" 13.6 3.3 36.4 3.7 39.1 2.2 4.9 34.1 86.9 1.4 9.8 9.8 9.6 1.4 3.4 1.0 1.8 1.3 6.4 56.9 34.5 5.8 2.5 1.4 5.2 59.7 41.9 1.2 3.4 14.6 6.3 1.6 61.1 1.9 7.0 59.0 1.9 1.5 73.9 1.0 10.3 1.8 34.1 3.5 3.9 31.4 51.5 2.8 3.4 43.7 2.7 3.0 1.0 58.1 0.2 7.1 29.3 10.7 8.8 4.4 13.4 0.3 8.9 1.9 1.3 3.3 3.1 0.0 4.2 0.5 6.9 0.2 26.0 0.1 1.6 100.9 8.9 0.0 2.9 4.7 1.7 1.4 10.9 2.4 0.1 3.7 0.1 1.5 0.2 4.7 16.0 0.3 3.6 8.0 4.4 0.8 4.8 5.5 21.1 0.0 0.3 0.1 3.4 3.2 5.1 24.0 5.3 0.1 11.5 6.5 0.7 5.1 0.2 1.9 2.3 14.4 9.6 50.6 45.5 0.1 0.8 0.1 15.1 2.2 0.2 0.3 1.6 0.1 3.4 0.2 3.4 2.7 0.1 0.4 5.8 3.9 1.2 0.7 0.2 0.3 1.3 1.0 36.4 39.1 34.1 86.9 56.9 34.5 59.7 41.9 61.1 34.1 51.5 58.1 2.8 3.2 3.3 33.3 1.5 2.0 0.8 0.2 0.6 114.1 0.8 0.9 9.0 11.5 1.3 1.8 189.7 0.6 5.0 5.3 0.0 1.9 27.8 0.6 3.7 4.4 2.4 5.5 64.6 1.1 0.4 3.1 0.0 1.5 0.0 0.9 0.7 4.3 0.4 180.0 92.7 7.4 0.0 0.8 6.0 29.1 11.5 1.1 1.8 3.7 1.4 35.9 8.2 62.8 35.0 0.1 3.4 13.9 2.1 0.9 19.3 9.1 0.7 70.9 0.0 2.9 1.3 22.7 25.0 0.0 2.3 0.3 15.5 1.3 18.2 1.5 RNF167 DKFZP566H073 ENSG00000108523 "Ring finger protein 167" Q9H6Y7 17 4940008-4945222 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049810 Approved Approved "Vesicles,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 5: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Vesicles, Cytosol" "Mitotic spindle, Centriolar satellite" "HPA049810: AB_2680894" "unprognostic (1.13e-1)" "unprognostic (5.12e-2)" "unprognostic (2.29e-3)" "unprognostic (1.63e-2)" "unprognostic (3.43e-2)" "unprognostic (7.32e-2)" "unprognostic (2.18e-1)" "unprognostic (6.77e-2)" "unprognostic (7.46e-2)" "unprognostic (2.07e-2)" "prognostic favorable (2.03e-6)" "unprognostic (2.16e-1)" "prognostic favorable (4.47e-4)" "unprognostic (7.62e-2)" "unprognostic (1.93e-1)" "unprognostic (3.26e-1)" "unprognostic (1.12e-1)" 75.0 110.6 141.9 53.0 146.7 69.0 73.1 146.4 179.9 93.2 138.6 111.5 66.6 94.9 76.4 122.1 84.3 45.3 131.8 141.5 146.4 106.7 184.2 77.5 64.5 146.3 145.4 87.4 115.1 105.8 96.8 50.7 146.3 95.0 65.7 98.1 92.5 70.5 152.9 127.8 100.5 52.8 142.4 113.8 111.8 110.6 150.3 98.1 93.4 94.2 71.6 106.7 90.4 153.3 102.6 143.1 61.1 73.7 132.8 68.7 92.7 63.4 76.1 119.7 93.4 96.2 43.3 71.5 120.3 93.5 63.9 147.5 103.2 114.8 86.1 74.5 166.1 121.9 164.4 94.9 100.6 59.0 245.0 79.6 176.5 129.8 116.2 74.6 77.2 101.0 49.9 237.5 96.2 66.3 92.8 70.6 75.4 102.0 86.8 62.8 61.9 91.5 137.3 77.4 49.2 61.1 56.0 92.9 81.9 83.1 87.3 55.9 49.5 76.6 48.3 66.8 119.3 79.5 88.0 23.7 98.4 80.6 77.9 108.4 88.8 236.9 195.3 94.0 153.4 100.4 148.0 195.7 73.9 98.7 103.2 152.2 219.8 118.8 117.7 75.9 153.0 177.0 141.9 146.7 146.4 179.9 141.5 146.4 146.3 145.4 146.3 142.4 150.3 153.3 36.9 0.0 3.9 12.4 54.3 68.6 44.4 65.8 51.8 43.2 56.6 44.7 15.8 77.2 38.9 49.7 20.9 120.1 64.7 65.2 56.7 78.5 59.6 29.8 25.1 36.4 31.8 60.6 11.3 66.7 139.7 36.3 36.2 32.2 14.0 26.3 45.7 95.1 58.4 18.5 11.2 45.7 65.1 41.3 43.6 86.5 48.7 36.1 39.2 6.5 53.1 46.9 114.4 10.1 17.9 60.7 44.9 53.8 59.1 32.6 108.2 64.0 31.1 32.3 39.5 28.4 35.1 127.1 106.7 61.4 83.3 125.2 82.5 37.2 59.6 48.0 RNF182 MGC33993 ENSG00000180537 "Ring finger protein 182" Q8N6D2 6 13924446-13980310 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.7;choroid plexus: 12.7" "Cell type enriched" "Detected in some" 4 "Astrocytes: 85.2" "Cancer enhanced" "Detected in many" "glioma: 5.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 81.3;RPTEC TERT1: 67.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012309 Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 20: HeLa - Mitochondria" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Golgi apparatus" Vesicles "HPA012309: AB_1856349" "unprognostic (1.29e-1)" "unprognostic (1.06e-2)" "unprognostic (2.74e-1)" "prognostic unfavorable (4.66e-5)" "unprognostic (6.16e-2)" "unprognostic (2.08e-1)" "unprognostic (9.01e-2)" "unprognostic (6.12e-2)" "unprognostic (1.71e-2)" "unprognostic (4.21e-1)" "unprognostic (6.04e-2)" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (9.33e-5)" "unprognostic (6.66e-3)" "unprognostic (1.33e-3)" "unprognostic (1.26e-1)" 1.1 0.1 12.2 0.1 13.3 8.4 0.6 22.5 17.7 0.8 12.7 0.2 0.2 0.6 1.1 0.3 1.2 0.2 0.3 17.6 12.2 1.1 0.0 3.3 0.2 16.9 17.7 0.3 1.7 5.8 1.8 1.3 16.5 0.4 0.1 8.8 1.3 2.1 0.2 0.4 0.3 0.3 14.2 0.2 0.2 3.7 24.7 1.5 1.3 0.1 0.0 0.3 0.4 12.2 0.2 6.5 12.0 0.0 4.1 5.0 0.7 6.3 8.6 17.0 16.4 0.3 0.1 0.0 0.1 6.8 18.5 0.0 14.3 0.1 30.9 0.0 4.7 0.4 81.3 0.0 0.0 0.1 0.0 2.8 0.0 26.3 0.2 19.5 0.3 3.5 0.5 0.0 11.9 0.2 0.1 2.2 6.9 0.1 23.9 3.8 2.9 1.0 67.3 0.0 14.2 13.7 0.6 0.0 24.8 4.4 0.0 2.4 6.5 20.7 4.4 0.2 14.3 0.0 0.0 0.0 14.1 0.0 30.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 13.3 22.5 17.7 17.6 12.2 16.9 17.7 16.5 14.2 24.7 12.2 0.2 0.0 0.0 85.2 0.1 0.3 0.1 0.0 0.0 19.3 0.2 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.6 0.4 0.1 0.2 0.0 9.7 8.6 0.0 0.1 0.4 0.0 0.1 0.0 5.4 0.0 0.1 0.1 15.2 1.5 0.1 0.0 0.0 0.3 1.4 0.3 0.0 0.0 5.6 0.0 14.7 0.0 2.5 0.4 0.1 0.0 0.0 0.0 0.1 0.0 1.1 0.1 1.3 6.6 0.0 1.3 5.7 3.2 0.0 0.0 0.3 0.3 0.0 0.1 0.1 RNF26 MGC2642 ENSG00000173456 "Ring finger protein 26" Q9BY78 11 119334527-119337309 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 66.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027620 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 85: Liver - Metabolism" "Cluster 1: K-562 - Erythropoiesis" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Vesicles, Cytosol" "HPA027620: AB_1856356" "unprognostic (9.23e-3)" "unprognostic (3.54e-2)" "unprognostic (1.36e-1)" "unprognostic (8.68e-3)" "unprognostic (3.40e-1)" "unprognostic (1.07e-2)" "prognostic unfavorable (3.19e-4)" "unprognostic (2.14e-2)" "unprognostic (3.26e-1)" "unprognostic (1.69e-1)" "unprognostic (7.24e-3)" "unprognostic (6.22e-2)" "prognostic favorable (3.45e-6)" "unprognostic (9.61e-2)" "unprognostic (3.50e-2)" "unprognostic (4.41e-2)" "prognostic unfavorable (7.73e-4)" 14.3 15.8 12.7 11.5 12.6 22.0 13.3 13.7 15.1 15.4 10.6 19.2 14.5 23.5 10.3 20.9 16.6 10.5 13.2 12.7 12.5 13.6 23.6 12.4 11.8 15.2 13.1 17.1 13.8 18.5 10.4 14.2 15.5 14.8 12.6 8.4 14.9 18.6 8.5 15.7 17.0 19.0 12.7 14.6 19.1 15.1 14.7 13.3 13.2 7.1 12.8 18.9 14.2 13.1 43.8 47.4 43.4 51.4 41.8 32.8 46.0 46.3 49.7 52.8 41.5 80.6 88.9 38.3 62.5 55.5 80.1 77.2 61.9 69.8 33.0 46.0 34.2 101.0 21.8 67.3 31.9 42.8 40.4 34.3 35.2 66.1 59.0 34.7 40.8 58.1 50.0 58.4 36.9 94.9 39.5 44.3 43.5 50.2 59.8 40.5 44.5 30.4 32.7 31.1 30.8 29.9 37.4 46.8 12.5 41.4 106.1 35.4 27.0 63.5 41.8 33.7 43.0 14.0 24.6 0.4 21.3 71.0 50.6 9.5 21.6 5.6 20.8 19.2 13.4 11.1 15.7 18.4 19.0 16.7 17.5 15.5 1.5 14.0 20.2 11.0 8.7 24.9 12.7 12.6 13.7 15.1 12.7 12.5 15.2 13.1 15.5 12.7 14.7 13.1 5.1 3.2 9.4 1.0 9.1 6.9 13.3 15.4 12.5 9.2 10.9 9.8 0.8 22.8 11.1 11.0 2.1 44.0 6.2 9.3 5.9 20.8 6.6 5.9 7.9 8.6 13.8 18.5 3.2 17.0 66.0 11.5 9.2 5.9 7.6 16.9 11.4 23.4 21.5 5.0 2.9 13.0 8.2 14.8 5.9 8.6 14.0 6.6 1.8 1.0 11.6 11.6 15.5 4.5 2.7 14.1 7.5 17.7 4.3 14.2 15.6 12.5 4.8 9.4 6.6 6.5 10.6 19.9 10.5 14.3 8.5 24.4 8.3 8.8 18.6 9.8 RNF39 "FAP216, HZFw1, LIRF" ENSG00000204618 "Ring finger protein 39" Q9H2S5 6 30070266-30075887 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 24.5;skin 1: 63.3;vagina: 21.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 79.9;Basal respiratory cells: 96.2;Club cells: 55.7;Prostatic glandular cells: 57.2;Urothelial cells: 233.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 4.5;U-266/84: 3.6" "Region enhanced" "Detected in many" "cerebral cortex: 8.1" "Group enriched" "Detected in many" 4 "cerebellum: 9.0;cerebral cortex: 8.0;hippocampal formation: 4.4" "CAB019278, HPA047115" Uncertain Approved "Vesicles,Plasma membrane,Centrosome" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Plasma membrane, Centrosome" "CAB019278: , HPA047115: AB_2679938" "unprognostic (1.05e-2)" "unprognostic (3.75e-2)" "unprognostic (1.73e-1)" "unprognostic (1.53e-2)" "unprognostic (5.72e-3)" "unprognostic (3.08e-2)" "unprognostic (4.05e-2)" "unprognostic (1.38e-1)" "unprognostic (2.22e-2)" "unprognostic (1.59e-2)" "unprognostic (4.45e-3)" "unprognostic (3.61e-2)" "unprognostic (2.06e-4)" "unprognostic (5.61e-2)" "unprognostic (1.31e-1)" "unprognostic (2.04e-1)" "unprognostic (2.57e-2)" 1.1 0.8 0.0 0.0 0.1 0.0 8.6 0.1 0.3 16.8 0.0 0.6 0.2 0.6 0.0 24.5 1.4 0.1 0.3 0.1 0.1 0.4 0.2 1.9 0.0 0.2 0.0 1.3 1.7 0.1 1.4 0.0 0.2 7.2 0.0 0.5 15.8 0.1 0.4 63.3 0.5 0.0 0.0 0.2 8.3 1.6 0.1 0.0 0.4 0.0 0.4 3.9 21.6 0.1 1.2 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.2 1.1 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.7 0.0 0.9 0.3 0.2 0.0 0.4 0.0 0.5 0.0 4.5 0.0 0.1 0.1 0.0 0.8 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.8 3.6 0.3 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.2 0.0 0.2 0.0 0.1 0.1 0.3 3.2 2.7 0.0 0.0 17.8 79.9 96.2 42.1 0.5 23.7 28.6 0.3 7.2 55.7 0.0 0.0 0.0 0.8 1.8 0.0 6.4 0.6 3.6 2.4 1.1 0.0 0.0 0.0 3.3 0.0 1.2 17.3 20.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 14.2 0.0 2.1 0.0 1.2 0.4 3.6 0.0 0.6 0.0 0.0 0.0 0.0 24.2 2.2 1.2 0.0 57.2 0.1 0.0 13.0 0.4 0.0 0.0 3.0 0.1 0.4 11.3 23.9 0.7 0.6 0.0 0.9 233.1 ROBO3 "FLJ21044, HGPPS, HGPS, RBIG1" ENSG00000154134 "Roundabout guidance receptor 3" Q96MS0 11 124865432-124881471 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 6.4" "Cell type enhanced" "Detected in many" "Astrocytes: 32.3;Muller glia cells: 45.3" "Cancer enhanced" "Detected in many" "glioma: 5.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "AF22: 18.4" "Region enhanced" "Detected in single" "cerebral cortex: 2.1" "Low region specificity" "Detected in many" HPA071053 Approved "Vesicles,Plasma membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Vesicles "HPA071053: " "unprognostic (1.30e-1)" "unprognostic (2.17e-1)" "unprognostic (4.95e-3)" "unprognostic (3.42e-2)" "unprognostic (3.84e-2)" "unprognostic (6.25e-2)" "unprognostic (6.95e-3)" "unprognostic (9.65e-2)" "unprognostic (1.56e-2)" "unprognostic (1.18e-1)" "unprognostic (1.32e-1)" "unprognostic (7.15e-2)" "unprognostic (3.75e-8)" "unprognostic (7.27e-3)" "unprognostic (2.21e-1)" "unprognostic (1.47e-1)" "unprognostic (4.91e-3)" 2.8 1.8 0.5 0.0 0.3 0.2 1.9 0.0 3.2 0.7 0.0 1.3 0.3 0.8 0.0 0.7 2.0 0.0 1.8 0.7 0.2 1.6 0.4 1.1 0.1 0.9 0.9 6.4 0.7 0.0 0.8 0.2 0.2 1.4 0.0 0.2 1.2 0.0 0.5 0.7 0.9 0.8 0.2 1.6 0.6 1.2 1.7 0.0 1.4 0.0 0.0 0.7 1.2 0.9 0.0 0.0 18.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 1.3 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 1.1 0.0 0.0 1.5 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.2 0.0 0.1 0.0 0.0 0.4 0.3 0.0 0.1 0.2 0.3 0.0 0.1 0.1 0.0 0.6 0.9 0.0 0.9 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.3 0.0 3.2 0.7 0.2 0.9 0.9 0.2 0.2 1.7 0.9 13.2 0.0 7.3 32.3 0.4 2.9 14.5 16.2 4.0 1.9 5.9 10.9 2.7 1.5 5.9 12.9 0.0 0.2 8.5 2.1 0.0 9.3 0.4 0.4 0.5 11.4 3.5 2.1 6.9 0.8 0.2 19.0 0.5 0.7 8.9 19.0 7.5 0.3 1.6 0.0 2.3 2.4 10.2 1.6 20.1 0.6 13.4 8.0 3.6 11.2 1.6 45.3 8.2 4.5 9.2 1.2 2.5 8.2 0.7 8.2 1.0 0.8 0.6 2.1 0.0 14.3 4.4 10.1 10.8 2.3 1.0 0.1 3.6 3.5 2.7 6.5 ROS1 "c-ros-1, MCF3, ROS" ENSG00000047936 "ROS proto-oncogene 1, receptor tyrosine kinase" P08922 6 117287353-117425942 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "epididymis: 58.6;lung: 31.7" "Cell type enriched" "Detected in some" 4 "Alveolar cells type 2: 78.5" "Cancer enriched" "Detected in some" 13 "lung cancer: 6.9" "Region enriched" "Detected in single" 4 "cerebral cortex: 2.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "GAMG: 19.3;HSkMC: 10.1;hTCEpi: 21.7;LHCN-M2: 14.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049098, HPA072424" Uncertain Approved Vesicles NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 30: Epithelial cell lines - Translation" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA049098: AB_2680628, HPA072424: AB_2686519" "unprognostic (8.18e-2)" "unprognostic (4.64e-3)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (7.57e-2)" "unprognostic (2.05e-2)" "unprognostic (1.57e-1)" "unprognostic (1.79e-1)" "unprognostic (2.79e-2)" "unprognostic (1.00e-2)" "unprognostic (2.42e-1)" "unprognostic (5.20e-2)" "unprognostic (1.56e-12)" "unprognostic (1.09e-2)" "unprognostic (2.81e-1)" "unprognostic (1.91e-1)" "unprognostic (2.12e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.2 0.0 0.4 0.0 0.0 58.6 0.0 0.1 0.0 0.0 0.6 0.0 0.3 0.1 31.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.4 0.0 0.0 2.2 0.4 0.3 0.2 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 0.3 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 10.1 21.7 0.2 1.9 0.0 0.0 0.0 0.0 0.0 14.9 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 2.0 0.0 3.1 1.7 0.2 2.1 0.0 0.0 0.0 1.9 3.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 16.0 78.5 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.8 0.0 3.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.3 1.8 0.2 0.0 0.0 0.0 17.8 0.0 0.0 0.2 0.0 1.5 1.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 1.3 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 RP9 PAP-1 ENSG00000164610 "RP9 pre-mRNA splicing factor" Q8TA86 7 33094797-33109404 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031523, HPA050778" Uncertain Enhanced Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" Nucleoplasm "Vesicles, Cytosol" "HPA031523: AB_10603235, HPA050778: AB_2681233" "unprognostic (1.12e-1)" "unprognostic (1.80e-1)" "unprognostic (1.07e-2)" "unprognostic (1.82e-1)" "unprognostic (6.65e-2)" "unprognostic (1.84e-1)" "prognostic unfavorable (2.58e-4)" "unprognostic (6.71e-2)" "unprognostic (6.22e-2)" "unprognostic (7.53e-2)" "unprognostic (7.03e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.65e-5)" "unprognostic (4.19e-2)" "unprognostic (2.63e-2)" "unprognostic (2.70e-1)" "unprognostic (1.61e-1)" 12.6 15.0 26.3 8.7 26.1 21.6 12.6 28.0 51.2 17.0 26.7 16.7 9.0 14.4 15.5 10.1 14.0 6.2 29.2 25.8 26.3 17.2 13.8 12.0 15.6 26.6 26.3 16.2 20.2 10.5 10.3 10.2 26.7 14.4 9.8 16.7 11.5 11.7 36.3 13.8 15.9 8.4 25.8 20.8 13.5 18.1 26.9 13.8 16.0 34.3 16.7 14.3 13.1 27.4 20.9 28.8 29.7 34.1 18.5 17.2 14.3 26.4 21.6 28.9 23.0 25.6 14.6 26.2 17.0 21.1 35.4 20.4 36.4 22.0 36.8 11.9 25.1 19.2 22.8 24.4 32.4 26.0 13.0 17.5 20.2 32.8 64.5 23.3 24.0 27.1 35.2 23.0 29.1 42.6 27.7 69.6 25.4 27.2 21.9 28.2 26.4 17.1 21.1 19.3 28.7 39.5 18.7 39.6 46.2 35.1 20.8 35.0 19.4 28.4 40.9 25.6 42.8 38.1 37.2 51.7 20.0 36.3 56.1 21.9 12.0 21.6 15.2 9.8 14.1 57.8 16.3 17.4 13.2 77.3 19.1 18.0 2.0 15.7 12.5 28.4 15.8 8.8 26.3 26.1 28.0 51.2 25.8 26.3 26.6 26.3 26.7 25.8 26.9 27.4 21.3 12.8 10.1 4.9 35.6 21.0 15.1 11.3 29.0 15.8 17.7 27.9 41.7 17.2 10.9 14.7 14.6 20.2 16.8 12.6 21.5 16.0 5.6 14.6 28.2 24.1 10.2 19.4 6.5 15.8 20.0 20.4 20.4 16.6 3.8 26.8 15.4 16.4 18.4 8.4 7.5 19.3 24.4 10.1 14.9 3.2 18.0 12.0 23.2 5.6 10.1 21.9 21.6 3.0 8.7 14.6 8.0 16.1 24.4 22.9 16.1 18.6 8.5 16.4 26.3 19.4 30.3 31.6 54.3 24.4 18.0 10.4 19.9 22.9 18.4 12.0 RPIA ENSG00000153574 "Ribose 5-phosphate isomerase A" P49247 2 88691673-88750929 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.6" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 234.3;Erythroid cells: 167.9;Syncytiotrophoblasts: 225.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042620, HPA057954" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA 2500000 "Cluster 26: Non-specific - Mitochondria" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Vesicles, Plasma membrane" "HPA042620: AB_10793980, HPA057954: AB_2683563" "unprognostic (3.35e-2)" "unprognostic (1.35e-2)" "unprognostic (6.96e-2)" "unprognostic (9.24e-2)" "unprognostic (4.31e-1)" "unprognostic (8.24e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (2.73e-3)" "unprognostic (1.82e-3)" "unprognostic (8.70e-2)" "unprognostic (8.82e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (8.53e-6)" "unprognostic (3.47e-2)" "unprognostic (2.53e-1)" "unprognostic (1.01e-2)" "unprognostic (8.79e-3)" 17.2 11.0 7.4 19.6 7.6 89.6 16.0 8.3 8.9 13.4 8.0 22.7 22.1 13.2 9.5 24.1 14.6 11.7 16.0 7.3 8.2 10.6 7.8 12.2 28.0 7.8 7.5 13.7 17.9 7.4 8.2 33.8 7.5 8.9 23.0 4.1 15.9 8.1 29.9 11.9 18.9 12.5 7.8 19.2 18.9 9.6 8.0 40.4 9.7 17.1 32.4 16.5 12.5 7.9 29.7 17.0 33.7 26.9 23.4 23.9 73.8 16.1 15.1 26.1 17.8 61.1 38.2 150.1 34.3 18.7 35.8 17.7 42.4 13.5 40.9 71.9 55.3 60.2 11.0 60.7 23.7 111.5 42.4 22.1 11.2 23.3 35.9 13.0 37.4 78.7 65.7 25.3 24.8 46.5 123.4 97.2 30.7 97.6 27.7 63.5 40.1 36.8 21.7 47.1 24.0 27.4 19.4 24.8 39.3 18.3 13.5 45.3 21.4 15.5 40.7 51.2 46.7 19.7 17.2 149.3 15.9 99.4 22.5 10.6 16.0 36.4 16.9 16.7 21.4 31.4 23.5 25.1 22.7 23.5 33.4 27.8 3.9 21.9 21.9 10.9 22.0 20.6 7.4 7.6 8.3 8.9 7.3 8.2 7.8 7.5 7.5 7.8 8.0 7.9 38.9 12.8 13.2 4.6 43.2 37.3 21.3 31.2 21.6 8.7 22.2 18.2 13.7 14.3 22.7 20.2 2.1 234.3 37.1 20.6 9.8 21.7 8.1 28.0 23.3 35.0 19.2 167.9 13.3 34.2 98.9 23.5 31.1 43.2 21.6 30.7 24.3 7.1 43.8 13.5 15.7 26.9 26.4 23.1 33.9 4.0 19.9 23.7 40.9 11.2 32.4 5.2 60.8 13.6 13.3 22.8 28.1 18.8 35.8 41.7 20.6 18.7 10.1 4.8 19.7 19.8 18.0 28.4 33.4 37.6 40.9 225.6 38.8 37.8 58.5 43.7 RPL7A "L7A, SURF3, TRUP" ENSG00000148303 "Ribosomal protein L7a" P62424 9 133348218-133351426 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046794 Approved Nucleoli,Vesicles NA NA 490000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Nucleoli Vesicles "HPA046794: AB_2732534" "unprognostic (5.01e-2)" "unprognostic (1.49e-1)" "unprognostic (8.83e-3)" "unprognostic (1.07e-3)" "unprognostic (4.17e-3)" "unprognostic (7.95e-2)" "prognostic unfavorable (8.99e-4)" "unprognostic (1.98e-1)" "unprognostic (8.88e-2)" "prognostic unfavorable (3.60e-5)" "unprognostic (4.91e-2)" "unprognostic (2.15e-1)" "unprognostic (1.55e-1)" "unprognostic (4.09e-2)" "unprognostic (4.06e-2)" "unprognostic (1.92e-2)" "unprognostic (9.89e-2)" 1864.3 2099.0 555.5 499.0 565.3 1295.5 1857.6 551.6 615.8 2259.5 549.3 1694.1 544.2 1635.0 1065.1 2717.9 1828.7 498.1 1316.3 539.3 556.2 1385.9 1390.8 1257.4 1006.5 570.3 558.1 3860.4 4112.2 606.1 1325.3 534.3 570.5 1665.0 909.8 237.3 1758.0 610.4 1999.9 2751.6 1419.1 767.3 588.2 1542.6 1762.7 692.1 563.8 1108.8 1287.3 862.8 1354.0 1718.9 2072.4 577.6 738.0 1094.6 1223.6 1227.0 2101.3 3459.0 1165.5 904.3 1835.4 1592.3 882.0 1676.1 941.1 2286.8 542.9 1587.3 858.2 1754.6 1831.4 2172.0 1273.6 977.8 1036.3 807.6 1533.7 1656.6 1389.2 1932.4 915.0 3509.5 3187.7 1154.6 1984.2 2581.3 2055.4 1579.3 1573.5 1170.9 1855.9 2494.0 1509.9 2010.8 1336.2 3265.2 1067.1 1307.0 1533.0 2946.8 2077.6 925.6 1144.0 1009.2 739.8 1878.6 1209.1 1008.0 2050.7 2009.1 1133.2 1042.8 746.6 950.3 1094.7 453.3 975.5 1410.1 814.8 1328.8 830.2 115.2 309.8 65.6 395.1 280.0 583.3 624.2 535.6 488.8 452.9 544.4 591.3 560.4 43.6 433.2 255.0 449.1 453.7 959.4 555.5 565.3 551.6 615.8 539.3 556.2 570.3 558.1 570.5 588.2 563.8 577.6 2135.7 519.2 830.9 22.5 3484.9 3244.6 4561.0 2878.3 4056.7 324.7 4450.1 8182.0 389.0 1720.0 1397.0 597.7 143.9 3617.6 2668.7 1136.8 2122.9 2037.3 1992.4 1277.7 3110.1 1843.9 1503.3 2592.1 30.3 4412.9 5135.5 1931.5 1701.4 1613.2 851.9 3717.2 1779.5 1292.4 2514.0 131.2 28.5 2769.2 876.9 2202.6 2161.8 4012.3 3736.3 2023.9 1511.9 22.5 2569.6 1085.1 2398.6 22.6 34.9 2672.7 2176.1 1929.6 3366.8 4776.6 2603.2 2708.5 569.1 516.9 966.3 2340.4 2271.5 1087.3 793.2 6499.1 3980.6 3307.4 2539.1 5934.2 3443.7 5327.8 RPRD2 "FLJ32145, HSPC099, KIAA0460" ENSG00000163125 "Regulation of nuclear pre-mRNA domain containing 2" Q5VT52 1 150363091-150476566 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 132.9;Inhibitory neurons: 133.8;Oligodendrocyte precursor cells: 136.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA061693 Approved Approved Nucleoplasm,Vesicles NA NA 66000 "Cluster 44: Non-specific - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 25: RPMI-8226 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Vesicles" "HPA061693: AB_2684587" "unprognostic (1.68e-1)" "unprognostic (1.52e-1)" "unprognostic (2.00e-1)" "unprognostic (7.25e-2)" "unprognostic (5.67e-3)" "unprognostic (3.79e-2)" "unprognostic (1.75e-2)" "unprognostic (9.03e-2)" "unprognostic (1.50e-1)" "unprognostic (3.93e-2)" "unprognostic (2.52e-1)" "unprognostic (1.27e-1)" "unprognostic (1.10e-3)" "unprognostic (1.11e-1)" "unprognostic (1.71e-1)" "unprognostic (7.92e-2)" "unprognostic (1.38e-1)" 10.8 11.4 6.1 10.8 7.4 13.7 12.0 17.4 11.0 16.0 3.2 13.2 10.6 18.9 14.2 14.0 21.1 10.7 13.2 7.3 8.1 16.0 11.4 12.9 13.6 4.2 5.3 29.8 14.5 19.2 10.7 9.8 4.3 14.3 14.5 17.4 14.0 16.2 24.5 12.8 12.1 17.8 3.8 14.0 11.9 14.1 7.7 19.5 23.0 22.8 15.7 12.7 11.3 7.9 24.6 18.4 23.9 24.3 24.3 20.5 22.6 17.4 20.7 18.8 18.4 16.1 29.4 38.8 19.5 21.4 10.4 26.6 34.0 25.9 20.4 17.9 14.2 22.3 21.2 19.5 17.4 33.8 26.3 21.8 19.3 26.2 34.4 20.9 23.5 23.2 22.1 40.9 19.3 35.4 29.8 10.9 30.0 30.9 20.6 27.0 17.7 39.4 27.7 22.4 25.4 25.6 35.6 30.0 22.6 21.2 23.7 29.5 21.7 17.3 17.8 14.6 24.9 24.9 29.5 28.7 17.2 24.8 17.4 5.8 2.9 3.5 5.6 1.8 5.1 5.4 5.3 4.5 2.6 5.2 6.1 6.2 1.4 3.9 7.3 3.1 7.0 2.4 6.1 7.4 17.4 11.0 7.3 8.1 4.2 5.3 4.3 3.8 7.7 7.9 18.7 19.2 25.9 97.3 30.8 15.4 10.5 17.1 25.0 35.0 22.0 19.8 27.6 17.2 24.5 33.1 16.7 14.0 27.2 20.6 7.9 14.6 11.0 31.8 30.1 21.6 25.8 16.8 132.9 12.9 9.1 23.4 16.8 33.5 17.7 28.5 26.0 27.1 14.7 11.8 133.8 22.1 18.3 22.6 10.5 6.6 37.9 16.6 10.6 56.2 18.6 22.9 27.8 136.2 112.2 14.1 17.7 39.9 29.6 16.4 21.6 30.8 29.9 29.8 32.9 37.1 20.6 21.1 21.3 26.4 14.6 10.0 27.6 27.3 22.3 16.9 RPS12 S12 ENSG00000112306 "Ribosomal protein S12" P25398 6 132814569-132817564 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006124, HPA006365" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA 450000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" Cytosol "Golgi apparatus, Vesicles" "HPA006124: AB_1856460, HPA006365: AB_2667570" "unprognostic (6.58e-2)" "unprognostic (3.31e-2)" "unprognostic (1.46e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-2)" "unprognostic (6.37e-2)" "unprognostic (4.95e-3)" "unprognostic (1.46e-1)" "unprognostic (3.95e-2)" "unprognostic (1.01e-2)" "unprognostic (2.31e-1)" "unprognostic (7.04e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (2.04e-1)" "unprognostic (1.05e-1)" "unprognostic (1.26e-1)" "unprognostic (5.66e-2)" 2199.7 1325.2 1393.3 1767.2 1454.1 5388.1 3551.2 1388.1 2027.8 2357.3 1375.8 1849.3 1597.8 1747.6 1664.7 2450.9 2149.5 1415.7 1311.3 1347.6 1419.0 1576.6 1443.7 1565.4 3948.0 1445.0 1406.0 4883.9 3660.2 1000.1 871.2 1633.7 1443.1 1696.0 1905.2 608.3 2167.8 1216.4 1965.9 3365.2 1692.7 1357.1 1484.2 2110.3 1718.3 682.0 1446.6 2534.1 1959.6 1376.9 3053.4 2011.6 2108.4 1482.0 1993.8 1568.3 2260.4 3581.3 4521.2 5855.0 2728.8 2502.9 3598.4 2772.7 2665.2 3294.5 1880.3 4497.8 3443.9 3368.1 1338.8 1900.3 2613.1 4373.5 2576.9 2895.0 3346.5 3013.3 1944.0 4743.1 5047.1 8481.4 2221.0 6167.0 7332.7 2340.5 8322.4 4658.3 3754.7 3556.4 5166.0 2858.9 3487.9 4342.3 3620.8 5030.3 2772.9 3420.0 2533.0 3993.0 1799.7 2884.6 3698.6 2185.9 1991.3 1573.0 833.4 5314.3 7184.2 2173.7 2276.5 8489.5 3027.8 1121.1 3111.7 3721.2 4696.8 4153.6 4104.8 3493.8 3635.1 5063.0 1621.7 599.0 1545.5 220.8 2412.5 1426.7 3728.9 4156.1 4210.9 3131.6 1971.7 3564.5 5201.1 4454.7 151.1 2031.9 1170.8 2722.3 2519.7 7450.3 1393.3 1454.1 1388.1 2027.8 1347.6 1419.0 1445.0 1406.0 1443.1 1484.2 1446.6 1482.0 3755.5 1660.2 3063.5 22.9 9470.7 8277.4 8259.7 3758.1 8926.6 531.5 10637.2 15674.0 827.7 3777.4 2693.4 1237.8 179.3 7566.9 6150.1 1808.1 4574.3 4058.0 792.6 1406.5 4602.8 3829.0 2863.4 5499.5 18.9 8085.7 9433.9 3353.4 3537.2 2309.6 1773.2 3890.7 4755.4 5136.7 5871.9 212.0 17.7 6806.4 1116.9 6161.6 5357.0 2335.6 6075.0 4790.9 3938.0 20.6 6667.5 2216.0 5160.7 10.1 25.0 6009.9 4480.8 2990.3 4762.0 10484.3 3517.1 5647.3 792.4 713.1 1617.2 5397.5 3117.8 1035.0 3063.2 11325.5 10512.6 7894.9 7990.4 4517.7 6783.0 9815.1 RPTOR "KIAA1303, KOG1, Mip1, raptor" ENSG00000141564 "Regulatory associated protein of MTOR complex 1" Q8N122 17 80544819-80966371 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 46.0;Excitatory neurons: 70.1;Inhibitory neurons: 66.3;Microglial cells: 32.8;Oligodendrocyte precursor cells: 50.8;Oligodendrocytes: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013514, HPA064306" Approved Enhanced Vesicles,Lysosomes NA NA "Cluster 35: T-regs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Lysosomes" "CAB013514: AB_2533523, HPA064306: AB_2685240" "unprognostic (5.09e-3)" "unprognostic (1.01e-1)" "unprognostic (1.79e-1)" "unprognostic (1.90e-1)" "unprognostic (1.38e-1)" "unprognostic (9.75e-2)" "unprognostic (3.34e-3)" "unprognostic (1.17e-2)" "unprognostic (9.63e-2)" "unprognostic (8.80e-2)" "unprognostic (4.40e-3)" "unprognostic (8.46e-2)" "unprognostic (6.03e-2)" "unprognostic (1.19e-1)" "unprognostic (2.90e-1)" "unprognostic (1.27e-2)" "unprognostic (1.77e-2)" 5.9 4.6 3.5 4.4 3.3 4.1 3.6 2.0 4.4 4.3 0.1 5.7 4.8 5.6 1.8 4.5 4.5 2.9 6.1 3.8 2.6 3.1 3.4 4.2 3.3 3.3 2.8 4.8 5.5 5.3 4.0 3.6 3.3 4.5 2.4 2.6 4.6 5.0 14.1 5.1 4.5 4.6 2.0 3.8 4.4 4.0 3.5 4.4 3.6 7.0 2.7 5.4 3.6 3.2 16.2 34.7 6.8 12.9 9.5 7.0 15.5 12.7 9.5 17.9 12.4 21.5 13.8 13.3 10.1 12.9 13.8 11.6 10.5 15.7 8.9 5.6 19.6 20.8 16.8 21.2 8.9 19.8 15.3 12.3 9.9 17.3 9.1 5.9 16.6 15.7 24.9 4.6 8.6 8.8 12.4 7.8 7.4 9.2 24.0 10.2 12.9 11.2 4.6 17.8 13.4 17.4 14.4 22.9 14.9 6.6 16.3 14.5 9.6 37.1 17.8 11.6 15.7 8.9 3.9 12.6 22.4 10.1 23.6 0.0 0.1 0.0 0.5 0.3 0.3 0.2 0.2 0.3 0.4 0.1 0.2 0.2 0.0 0.1 0.2 0.0 1.0 0.4 3.5 3.3 2.0 4.4 3.8 2.6 3.3 2.8 3.3 2.0 3.5 3.2 4.3 0.0 3.9 46.0 8.5 3.2 3.0 2.4 4.6 6.8 4.2 3.3 4.5 5.7 1.6 5.5 4.2 4.4 7.2 3.8 1.9 3.6 6.7 3.9 5.4 4.3 6.0 4.8 70.1 3.8 5.9 4.8 8.2 4.9 2.5 7.5 2.2 7.5 4.7 11.8 66.3 3.1 6.1 5.7 3.2 10.9 3.1 6.7 1.8 32.8 1.7 4.3 2.1 50.8 66.2 4.7 3.5 5.3 9.4 4.5 4.6 2.7 2.0 7.0 0.0 5.5 4.1 4.5 3.5 5.1 3.0 4.4 9.3 6.0 5.6 3.8 RRAGA "FIP-1, RAGA" ENSG00000155876 "Ras related GTP binding A" Q7L523 9 19049427-19051025 "Predicted intracellular proteins" "Apoptosis, Host-virus interaction" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003734 Supported Approved "Golgi apparatus,Vesicles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus, Vesicles" "HPA003734: AB_1079851" "unprognostic (6.30e-2)" "unprognostic (4.65e-1)" "unprognostic (1.37e-1)" "unprognostic (1.22e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (7.43e-4)" "unprognostic (6.74e-2)" "unprognostic (2.17e-2)" "unprognostic (2.11e-1)" "unprognostic (2.91e-1)" "unprognostic (2.20e-3)" "unprognostic (3.13e-1)" "unprognostic (2.65e-1)" "unprognostic (1.74e-2)" "unprognostic (4.88e-2)" "unprognostic (2.10e-3)" "unprognostic (1.05e-1)" 79.3 73.7 73.6 39.6 75.1 30.2 72.8 77.5 82.5 67.3 74.6 74.0 38.6 94.8 77.4 62.1 74.7 49.7 87.1 76.7 83.5 67.7 68.3 51.9 46.4 73.5 74.2 83.0 46.7 47.6 68.7 71.0 77.5 58.1 45.6 39.7 53.3 73.8 128.9 72.5 57.1 82.7 80.2 52.9 57.1 40.2 78.1 53.2 57.1 104.5 47.9 70.7 58.0 84.5 115.2 92.7 74.9 78.4 263.8 167.0 51.5 112.7 134.4 96.2 117.7 35.8 34.7 22.6 61.1 190.8 86.7 42.8 64.8 106.6 101.2 97.7 72.8 145.3 122.6 139.0 172.8 20.3 52.7 148.8 101.3 82.2 55.7 132.4 116.1 36.9 33.4 32.1 202.5 72.5 56.2 118.8 41.9 59.5 70.6 43.0 48.8 32.6 147.9 98.8 61.4 76.6 61.9 55.5 60.4 67.5 71.3 54.0 91.0 116.2 44.6 83.6 85.3 22.5 39.4 51.6 127.9 30.8 43.1 155.3 85.6 147.8 74.5 98.0 72.7 49.4 77.1 74.6 81.0 50.4 70.1 69.8 58.9 81.9 109.3 58.2 100.0 107.8 73.6 75.1 77.5 82.5 76.7 83.5 73.5 74.2 77.5 80.2 78.1 84.5 84.3 25.6 27.7 16.0 35.0 61.1 123.7 138.8 50.7 47.8 43.2 57.9 51.8 41.5 63.8 53.3 18.8 130.9 28.1 32.9 105.7 95.9 92.5 74.0 70.6 86.5 17.5 38.1 17.5 61.4 98.6 80.3 28.1 47.2 33.6 38.0 71.4 61.9 64.6 48.8 20.0 29.8 81.4 37.1 33.2 28.3 93.8 39.2 56.9 20.6 51.0 95.4 49.4 21.1 29.6 52.3 44.3 103.0 24.0 50.8 51.4 130.1 75.4 37.0 32.9 65.3 79.1 113.8 22.9 47.7 59.2 121.4 37.3 61.6 34.8 74.8 RRAGB ENSG00000083750 "Ras related GTP binding B" Q5VZM2 X 55717749-55758774 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 72.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003734 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 52: Non-specific - Transcription" "Golgi apparatus, Vesicles" "HPA003734: AB_1079851" "unprognostic (2.01e-1)" "unprognostic (2.82e-3)" "prognostic unfavorable (7.60e-4)" "unprognostic (2.44e-2)" "prognostic favorable (3.31e-5)" "unprognostic (2.58e-2)" "unprognostic (2.36e-1)" "prognostic favorable (3.64e-6)" "unprognostic (8.89e-3)" "unprognostic (1.56e-2)" "unprognostic (1.31e-2)" "unprognostic (2.71e-3)" "unprognostic (2.74e-2)" "unprognostic (3.35e-2)" "unprognostic (6.21e-2)" "unprognostic (1.23e-1)" "unprognostic (2.00e-3)" 12.6 14.8 13.1 7.1 13.4 8.2 14.7 11.0 12.9 14.0 9.9 12.3 6.9 18.5 34.7 8.9 20.5 13.0 15.2 13.5 14.2 16.2 8.0 11.1 8.3 11.2 14.0 22.2 8.0 23.1 14.9 11.4 12.5 16.4 9.6 17.1 8.9 18.0 12.0 12.1 8.8 17.3 12.4 11.3 9.6 9.2 15.2 10.2 22.9 15.9 8.7 12.0 10.0 12.5 11.9 8.9 10.0 7.6 34.7 32.2 2.6 10.3 19.0 9.1 12.2 5.2 7.7 3.5 72.6 14.4 7.6 7.5 9.1 5.8 8.4 6.5 12.7 5.2 12.1 10.5 24.6 8.4 8.0 38.4 21.9 6.8 8.8 36.8 12.3 9.3 7.3 8.1 15.3 8.8 4.5 11.7 10.4 3.2 14.4 17.0 11.1 10.0 13.9 15.3 10.0 8.9 14.2 4.4 15.6 25.4 12.9 8.8 6.8 11.2 5.2 10.4 5.6 11.1 16.4 6.7 8.5 18.2 5.0 7.1 4.7 4.1 5.0 6.7 7.5 6.8 6.5 6.9 7.3 10.4 7.4 7.5 1.4 6.5 3.9 4.6 7.5 4.0 13.1 13.4 11.0 12.9 13.5 14.2 11.2 14.0 12.5 12.4 15.2 12.5 14.5 12.8 17.4 22.9 16.0 8.7 15.3 16.1 19.4 20.4 9.7 10.2 16.4 4.3 10.4 18.4 14.6 7.4 6.8 4.9 27.4 9.8 1.8 14.3 16.1 12.7 4.2 11.1 32.4 5.0 5.5 15.6 10.7 11.9 17.1 16.7 5.7 2.6 7.3 20.2 29.6 5.1 8.2 5.4 7.8 2.9 9.9 7.9 5.4 23.4 7.8 27.0 2.1 28.6 38.2 4.3 10.8 15.4 6.4 9.0 7.3 19.3 10.4 25.6 0.0 17.9 16.6 7.7 14.6 11.2 7.7 4.8 11.8 26.9 6.9 6.9 RRAGC "FLJ13311, GTR2" ENSG00000116954 "Ras related GTP binding C" Q9HB90 1 38838198-38859772 "Disease related genes, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 224.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018247, HPA055489" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Vesicles" "HPA018247: AB_1856475, HPA055489: AB_2682832" "unprognostic (2.04e-2)" "unprognostic (1.58e-1)" "unprognostic (2.63e-2)" "unprognostic (1.41e-2)" "unprognostic (3.40e-1)" "unprognostic (1.42e-1)" "prognostic unfavorable (9.97e-9)" "unprognostic (2.14e-1)" "unprognostic (3.61e-2)" "unprognostic (4.98e-2)" "unprognostic (2.23e-2)" "unprognostic (1.71e-1)" "unprognostic (5.13e-2)" "unprognostic (6.38e-2)" "unprognostic (2.69e-1)" "unprognostic (2.77e-1)" "unprognostic (3.82e-2)" 37.0 16.9 18.0 16.6 19.2 30.2 25.2 20.0 19.4 17.1 16.4 21.5 18.7 16.1 14.0 24.9 13.9 17.7 21.6 17.6 20.4 24.5 18.5 19.3 20.5 20.4 21.3 21.6 14.2 24.0 10.0 28.5 21.3 14.9 17.0 16.1 14.2 16.9 17.4 29.8 16.2 21.9 19.5 17.3 15.1 17.5 19.8 18.8 16.7 18.9 21.8 19.0 18.1 21.3 37.0 16.6 21.3 23.3 110.7 74.6 33.0 33.7 68.6 44.8 47.2 12.7 23.9 23.0 18.9 52.6 71.8 21.7 40.1 22.2 36.8 37.6 28.3 22.1 19.2 14.7 135.6 26.0 23.9 66.7 55.2 48.0 61.9 35.4 47.5 24.5 22.9 44.9 65.7 10.2 19.0 14.7 27.2 15.9 28.0 18.1 37.6 15.6 31.6 42.5 11.1 16.5 27.0 20.0 73.2 47.5 18.3 19.5 42.5 54.3 22.4 60.0 29.2 35.0 60.5 26.8 50.5 29.1 28.8 0.5 2.4 5.5 1.7 2.3 2.9 3.3 2.6 2.2 2.3 3.6 2.2 2.1 5.9 1.7 1.8 8.4 2.5 1.6 18.0 19.2 20.0 19.4 17.6 20.4 20.4 21.3 21.3 19.5 19.8 21.3 31.2 32.1 28.0 6.5 42.1 111.9 47.1 19.2 40.9 20.0 31.0 25.0 22.2 24.3 16.1 12.9 12.5 84.9 38.4 30.3 11.7 55.7 56.3 32.0 26.6 34.3 14.4 24.0 7.4 48.1 57.7 39.4 12.2 42.9 16.5 16.9 35.7 14.2 72.1 38.7 8.3 10.3 20.3 34.4 65.0 49.8 30.7 49.2 53.4 9.4 63.3 43.4 10.3 7.5 15.8 47.0 14.0 37.2 20.1 47.3 21.5 30.4 15.0 22.8 19.7 28.1 37.5 24.7 28.5 46.1 140.5 224.1 23.3 18.6 12.2 51.1 RRAGD "bA11D8.2.1, DKFZP761H171" ENSG00000025039 "Ras related GTP binding D" Q9NQL2 6 89364616-89412273 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 84.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 129.1;Distal tubular cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.3" "Group enriched" "Detected in many" 7 "granulocytes: 3.3;monocytes: 2.4" "Cell line enhanced" "Detected in many" "Karpas-707: 63.9;SCLC-21H: 33.1;U-266/70: 80.0;U-266/84: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068664 Approved Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 80: Striated muscle - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Vesicles, Centrosome" "HPA068664: AB_2686016" "unprognostic (3.06e-1)" "unprognostic (1.10e-1)" "unprognostic (1.53e-3)" "unprognostic (1.09e-1)" "unprognostic (2.03e-1)" "unprognostic (2.09e-1)" "prognostic unfavorable (7.80e-4)" "unprognostic (3.75e-2)" "unprognostic (1.66e-2)" "unprognostic (4.33e-2)" "unprognostic (1.11e-2)" "unprognostic (1.00e-1)" "prognostic favorable (8.47e-8)" "unprognostic (8.41e-3)" "unprognostic (1.23e-1)" "unprognostic (9.46e-2)" "unprognostic (4.40e-2)" 9.8 9.1 14.0 2.3 18.9 11.6 8.2 31.8 16.1 9.4 17.9 4.0 1.7 1.5 6.9 13.8 13.7 3.6 38.4 15.9 13.9 26.5 4.4 7.0 2.8 16.4 12.2 1.6 6.4 22.7 11.4 3.2 17.2 6.1 1.8 21.8 52.2 2.8 84.5 6.7 2.0 2.1 21.5 4.8 1.7 6.9 14.8 5.5 28.1 60.3 2.5 5.8 6.2 23.8 0.1 1.7 4.4 3.3 0.4 0.0 0.3 0.0 0.0 0.5 0.9 0.1 0.1 0.0 1.5 0.0 22.6 0.1 24.5 0.1 0.0 0.0 12.1 5.8 0.1 0.1 1.8 16.9 19.0 0.4 1.5 0.0 0.1 0.0 0.0 16.9 0.5 63.9 0.1 1.8 8.2 8.4 3.6 0.0 1.8 16.8 23.1 0.2 5.8 0.6 33.1 1.8 0.6 2.2 28.8 1.3 0.7 13.2 0.0 1.8 2.8 11.5 3.0 80.0 39.8 0.0 6.1 12.5 1.9 2.6 0.6 1.4 0.0 0.5 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.3 3.3 0.1 2.4 0.3 0.0 0.1 14.0 18.9 31.8 16.1 15.9 13.9 16.4 12.2 17.2 21.5 14.8 23.8 1.4 9.6 16.7 5.2 3.7 16.2 17.0 5.8 4.0 21.7 17.4 9.7 129.1 17.2 13.9 14.7 31.3 0.6 4.7 0.1 117.4 20.2 25.6 10.4 2.5 4.8 1.2 5.0 17.6 16.9 1.5 10.0 1.1 15.0 4.5 2.9 2.5 9.7 51.9 47.1 20.6 0.5 42.7 25.8 9.2 15.5 3.1 23.2 39.2 3.7 10.4 29.6 0.0 13.0 17.2 8.1 0.0 4.1 8.0 28.4 0.0 18.6 19.4 16.3 0.0 11.8 7.0 21.7 30.3 32.4 22.6 0.7 3.9 0.2 0.2 30.2 RRAS R-Ras ENSG00000126458 "RAS related" P10301 19 49635292-49640143 "Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 215.6;Pancreatic endocrine cells: 150.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 20.9;non-classical monocyte: 25.0" "Lineage enriched" "Detected in many" 7 "monocytes: 25.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010160, HPA060364, CAB069439" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB010160: AB_2180086, CAB069439: AB_1622637, HPA060364: AB_2684264" "unprognostic (9.23e-2)" "unprognostic (6.37e-2)" "unprognostic (1.50e-1)" "unprognostic (9.86e-2)" "prognostic unfavorable (1.02e-4)" "unprognostic (8.54e-2)" "unprognostic (4.55e-3)" "prognostic unfavorable (5.28e-4)" "unprognostic (2.16e-2)" "unprognostic (7.58e-2)" "unprognostic (1.39e-3)" "unprognostic (2.30e-2)" "prognostic unfavorable (1.54e-9)" "unprognostic (6.13e-2)" "unprognostic (3.42e-2)" "unprognostic (7.14e-3)" "unprognostic (2.74e-2)" 167.4 59.1 36.6 43.6 36.8 5.2 129.6 35.7 49.4 162.6 33.9 241.7 40.3 187.0 24.9 58.4 168.3 47.1 201.9 34.4 39.0 99.2 40.9 168.9 37.2 40.1 36.2 79.9 31.1 14.6 28.5 63.5 38.1 147.8 23.6 4.9 52.8 160.2 51.9 52.9 89.5 84.2 37.2 100.2 117.7 35.3 39.7 15.0 83.8 49.8 20.1 173.3 139.4 35.4 82.1 99.4 12.5 25.3 212.7 236.1 3.8 105.8 148.7 50.6 65.9 13.7 134.2 5.1 54.0 156.8 73.2 53.6 7.3 108.5 20.7 33.4 5.5 9.7 32.3 8.4 197.2 0.6 20.3 167.3 95.1 63.9 50.7 213.5 130.4 3.7 6.4 39.1 91.3 32.4 0.5 9.3 2.5 69.5 80.0 7.7 30.4 15.3 111.4 16.3 0.2 11.6 41.5 36.8 6.7 32.4 52.5 7.8 187.3 147.3 58.9 26.0 30.9 28.7 13.0 1.3 153.1 6.3 47.4 0.0 5.4 0.1 0.6 20.9 0.5 2.0 1.6 0.5 3.7 0.4 1.7 0.4 0.0 0.6 25.0 1.0 0.7 2.2 36.6 36.8 35.7 49.4 34.4 39.0 40.1 36.2 38.1 37.2 39.7 35.4 215.6 38.5 7.9 2.3 6.2 29.6 54.4 126.4 11.4 1.7 44.4 57.4 61.1 27.1 48.7 51.5 2.1 4.9 7.4 60.8 9.8 65.9 0.9 12.5 90.0 75.4 10.2 3.6 1.2 55.7 41.2 76.6 16.3 29.9 10.2 2.3 79.2 7.1 31.5 5.0 0.6 22.2 30.5 28.3 23.2 6.1 60.3 32.1 26.6 8.4 32.9 59.1 4.1 0.0 0.8 150.4 33.0 76.0 6.0 62.0 53.3 10.7 14.5 2.5 78.9 35.2 135.9 1.8 5.4 11.9 19.2 7.1 9.4 9.3 17.8 54.4 RRP12 KIAA0690 ENSG00000052749 "Ribosomal RNA processing 12 homolog" Q5JTH9 10 97356358-97426076 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 90.9;skeletal muscle: 38.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 26.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049945, HPA074403" Supported "Nucleoli,Vesicles,Plasma membrane,Cytosol" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" Nucleoli "Vesicles, Plasma membrane, Cytosol" "HPA049945: AB_2680965, HPA074403: " "unprognostic (2.79e-1)" "unprognostic (7.65e-2)" "unprognostic (5.87e-3)" "unprognostic (1.10e-1)" "unprognostic (3.42e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.12e-8)" "unprognostic (2.64e-1)" "unprognostic (1.30e-2)" "unprognostic (1.54e-1)" "unprognostic (3.94e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (2.54e-5)" "unprognostic (2.58e-2)" "unprognostic (3.32e-1)" "unprognostic (4.81e-2)" "unprognostic (6.99e-3)" 8.1 10.2 2.6 9.2 3.4 90.9 5.6 1.1 7.6 5.6 2.4 4.9 6.0 7.4 3.6 8.5 7.3 7.2 11.4 3.2 2.7 6.8 5.7 6.7 6.7 4.3 4.4 6.1 16.0 9.3 10.2 4.3 4.1 6.3 3.8 3.4 8.3 4.0 38.5 10.3 4.7 6.0 0.2 7.6 6.3 10.9 3.7 4.7 5.5 9.7 6.1 9.3 5.7 4.6 38.9 50.8 13.2 28.6 10.0 11.6 28.9 24.2 14.4 24.2 18.7 55.6 35.0 42.3 30.4 15.1 21.6 48.7 36.3 28.0 16.3 23.1 44.2 32.8 19.5 43.6 16.5 51.7 41.5 12.2 38.6 59.9 54.6 27.0 13.7 23.5 47.7 27.4 14.0 50.8 35.0 33.0 57.0 20.4 34.0 38.1 18.0 42.1 16.8 21.4 17.7 37.9 19.2 18.1 24.1 10.4 43.7 26.5 18.2 16.1 27.9 36.5 76.4 55.7 52.7 48.6 23.2 64.9 17.9 0.4 11.2 6.9 2.7 13.6 3.3 3.9 1.6 2.2 6.2 4.2 2.5 2.8 26.7 1.9 16.9 5.0 1.2 6.0 2.6 3.4 1.1 7.6 3.2 2.7 4.3 4.4 4.1 0.2 3.7 4.6 8.8 35.3 31.1 5.9 18.5 23.5 14.2 5.1 25.0 5.8 12.7 9.9 11.6 7.2 21.5 14.7 41.7 5.2 7.7 10.6 0.0 8.7 7.2 17.1 10.6 10.6 21.5 7.2 15.1 8.7 7.5 13.5 27.0 20.1 41.7 12.9 3.9 8.9 11.5 5.0 9.5 13.8 4.1 12.5 7.1 4.8 3.7 30.3 7.2 2.8 12.3 1.9 3.1 5.0 4.4 8.5 6.4 2.6 31.8 17.1 3.7 6.8 24.6 12.7 0.0 19.4 6.7 10.6 20.6 22.7 19.6 9.2 11.0 13.5 11.5 13.6 RSBN1 "FLJ11220, ROSBIN" ENSG00000081019 "Round spermatid basic protein 1" Q5VWQ0 1 113761832-113812476 "Predicted intracellular proteins" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042124, HPA049484" Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Nuclear bodies, Vesicles" "HPA042124: AB_10794644, HPA049484: AB_2680787" "unprognostic (3.26e-2)" "unprognostic (1.32e-1)" "unprognostic (1.15e-3)" "unprognostic (2.13e-1)" "unprognostic (3.66e-2)" "unprognostic (2.30e-2)" "unprognostic (5.06e-2)" "unprognostic (6.60e-2)" "unprognostic (1.06e-1)" "unprognostic (1.97e-2)" "unprognostic (1.56e-1)" "unprognostic (3.96e-1)" "unprognostic (1.51e-2)" "unprognostic (4.67e-2)" "unprognostic (1.43e-1)" "unprognostic (1.24e-1)" "unprognostic (1.15e-3)" 6.4 6.0 4.6 7.7 4.7 34.4 8.2 12.7 6.1 7.9 2.8 8.4 6.2 10.3 6.5 7.3 7.9 6.4 5.2 4.2 5.3 8.0 6.4 7.5 10.6 3.1 3.7 14.2 11.0 11.0 5.1 6.6 3.2 7.9 8.6 13.7 6.8 6.9 8.0 7.5 7.5 7.0 3.9 9.2 6.8 10.7 4.3 12.3 9.0 7.9 10.5 6.4 5.5 5.2 14.6 4.1 13.7 8.2 8.0 9.2 6.6 5.1 10.9 10.1 10.5 4.9 4.3 12.7 7.9 6.3 4.6 6.2 9.8 6.2 16.4 12.3 7.1 9.6 4.4 5.6 6.0 18.1 9.9 7.0 6.7 8.6 8.2 8.6 8.1 14.0 14.7 7.7 7.5 14.9 14.7 10.8 11.6 4.6 6.9 26.3 13.4 6.6 6.0 6.2 13.8 11.0 9.7 9.4 8.7 6.8 4.5 12.1 9.7 9.0 9.7 13.5 8.3 10.3 8.2 15.9 9.3 10.9 15.4 53.3 14.5 25.6 29.1 11.7 29.3 32.2 31.2 27.2 12.8 33.1 31.9 26.2 29.0 25.4 13.4 27.3 30.6 12.6 4.6 4.7 12.7 6.1 4.2 5.3 3.1 3.7 3.2 3.9 4.3 5.2 37.4 35.3 20.1 16.0 52.7 74.7 39.2 26.9 45.5 90.0 35.0 46.7 21.5 24.3 29.6 25.8 66.7 26.3 68.0 55.5 19.6 22.3 25.6 26.2 39.4 38.9 49.4 37.5 34.3 26.0 24.1 41.5 17.9 28.8 36.1 23.4 32.5 18.7 19.2 97.6 34.2 58.5 28.5 26.3 37.7 9.0 50.4 25.7 40.9 30.9 35.0 56.7 62.8 33.7 34.6 21.2 54.0 49.7 34.7 44.3 40.2 17.2 27.8 106.5 39.5 43.8 54.9 96.8 37.0 34.3 65.1 31.5 84.8 24.2 52.7 37.8 RSKR "FLJ25006, SgK494" ENSG00000167524 "Ribosomal protein S6 kinase related" 17 28601827-28614197 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 5.8" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 7.1;Extravillous trophoblasts: 2.4;Hofbauer cells: 4.1;Syncytiotrophoblasts: 24.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Low region specificity" "Detected in many" HPA046590 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 77: Retina - Visual perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Vesicles, Plasma membrane" Nucleoplasm "HPA046590: AB_2679710" "unprognostic (1.83e-1)" "unprognostic (9.42e-2)" "unprognostic (2.84e-2)" "unprognostic (2.30e-2)" "unprognostic (2.11e-1)" "unprognostic (2.06e-3)" "unprognostic (9.33e-3)" "unprognostic (2.63e-1)" "unprognostic (8.62e-4)" "unprognostic (2.09e-2)" "unprognostic (6.81e-2)" "unprognostic (3.45e-5)" "unprognostic (1.20e-7)" "unprognostic (2.67e-1)" "unprognostic (1.10e-1)" "unprognostic (1.28e-2)" "unprognostic (4.66e-3)" 0.2 0.5 1.2 0.8 1.2 1.6 0.2 1.4 1.7 0.4 1.2 0.2 0.3 0.3 0.1 0.1 0.4 0.0 0.2 1.1 1.2 0.9 0.2 0.2 0.3 1.3 1.2 0.5 0.1 0.1 0.4 0.3 1.4 0.3 0.3 5.8 0.1 0.1 0.5 0.7 0.3 0.1 1.1 0.4 0.2 1.1 1.3 0.4 0.3 0.1 0.3 0.3 0.2 1.5 0.4 0.5 0.6 0.8 0.2 0.1 0.2 0.0 0.0 0.6 0.2 0.9 0.1 1.2 0.1 0.0 0.4 0.6 0.8 0.1 0.6 0.3 0.6 1.0 0.4 0.4 0.0 0.2 0.8 0.0 0.4 0.3 0.4 0.1 0.2 1.2 0.6 0.2 0.1 1.3 0.4 1.0 1.2 1.2 0.1 0.8 2.2 0.7 0.5 1.3 0.4 0.4 0.4 0.1 0.9 0.9 0.5 0.5 0.4 0.3 0.8 0.7 0.5 0.6 0.4 0.6 0.4 1.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.4 1.7 1.1 1.2 1.3 1.2 1.4 1.1 1.3 1.5 1.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 7.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 24.8 0.2 0.0 0.0 0.0 RSPO1 "FLJ40906, RSPONDIN" ENSG00000169218 "R-spondin 1" Q2MKA7 1 37611350-37634892 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Wnt signaling pathway" Heparin-binding "Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 28.9;endometrium 1: 41.4" "Cell type enhanced" "Detected in some" "Breast glandular cells: 7.7;Breast myoepithelial cells: 15.6;Fibroblasts: 5.4;Langerhans cells: 2.9" "Cancer enriched" "Detected in some" 13 "ovarian cancer: 11.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.2;THP-1: 1.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA046154, HPA062923" Uncertain Approved Vesicles "Secreted in female reproductive system" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 43: THP-1 - Innate immune response" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA046154: AB_10964912, HPA062923: " "unprognostic (1.50e-2)" "unprognostic (1.97e-3)" "unprognostic (5.99e-3)" "unprognostic (2.22e-1)" "unprognostic (1.76e-1)" "unprognostic (3.75e-6)" "unprognostic (1.84e-2)" "unprognostic (1.48e-1)" "unprognostic (1.27e-1)" "unprognostic (2.08e-1)" "unprognostic (1.13e-2)" "unprognostic (1.93e-2)" "unprognostic (3.76e-2)" "unprognostic (3.21e-1)" "unprognostic (1.53e-2)" 11.3 0.1 0.0 0.8 0.1 0.1 7.9 0.1 0.1 28.9 0.0 1.8 1.1 41.4 2.2 3.1 20.0 2.7 0.7 0.1 0.0 0.8 0.1 4.0 1.9 0.1 0.1 2.1 0.5 0.1 0.1 0.4 0.1 6.7 0.5 0.1 1.3 1.8 0.0 6.6 3.3 13.1 0.0 0.8 4.0 0.2 0.1 0.0 0.0 0.5 3.0 1.5 19.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 7.7 15.6 0.3 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.0 0.1 0.0 0.0 5.4 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 2.9 0.1 0.9 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.4 0.1 0.3 0.0 0.0 0.1 RSU1 "FLJ31034, RSP-1" ENSG00000148484 "Ras suppressor protein 1" Q15404 10 16590611-16817463 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025927 Uncertain Approved Vesicles NA NA 33000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA025927: AB_10610420" "unprognostic (7.33e-2)" "unprognostic (1.42e-1)" "unprognostic (2.08e-1)" "unprognostic (4.89e-1)" "unprognostic (9.56e-3)" "unprognostic (2.91e-2)" "unprognostic (1.25e-3)" "unprognostic (1.99e-1)" "unprognostic (3.83e-2)" "unprognostic (3.72e-2)" "unprognostic (3.30e-2)" "unprognostic (7.79e-2)" "prognostic unfavorable (9.32e-5)" "unprognostic (1.11e-1)" "unprognostic (1.46e-1)" "unprognostic (2.48e-1)" "unprognostic (4.53e-2)" 35.6 14.2 8.8 22.0 8.9 27.9 25.4 8.8 10.1 21.2 10.1 27.8 12.0 30.3 19.9 27.7 19.2 19.7 25.1 8.7 10.1 19.4 16.7 27.7 22.3 10.5 9.4 21.8 21.2 14.1 3.9 23.2 9.8 17.9 23.8 9.9 14.5 27.0 15.8 15.9 13.7 41.8 8.6 20.4 15.6 5.5 10.4 18.1 18.7 13.8 22.3 24.0 18.0 9.6 27.3 18.6 15.0 88.5 78.4 80.3 18.3 66.3 28.2 45.1 48.6 17.3 25.0 27.0 10.5 91.2 24.1 23.9 18.3 34.7 48.3 40.6 14.6 85.2 11.1 16.7 34.5 13.1 47.8 40.0 36.0 43.3 13.7 40.9 47.8 27.8 14.0 18.2 61.6 17.6 30.5 23.5 15.7 39.6 10.5 19.6 20.3 18.4 44.0 10.0 5.9 11.6 33.1 21.6 33.6 26.8 7.6 34.4 58.8 38.4 13.3 48.5 34.6 15.9 20.6 23.3 51.0 37.1 16.9 33.0 20.9 22.8 24.7 26.0 28.0 16.6 28.1 26.7 34.7 17.9 20.5 25.8 14.6 31.3 25.5 25.9 36.0 48.5 8.8 8.9 8.8 10.1 8.7 10.1 10.5 9.4 9.8 8.6 10.4 9.6 111.1 35.3 24.5 26.4 29.9 36.7 30.3 74.0 12.0 1.7 22.5 36.2 41.2 27.1 48.3 42.3 2.1 131.9 41.6 57.0 68.4 72.1 80.5 20.7 47.2 69.6 7.2 74.7 52.8 119.2 83.0 52.8 28.5 24.8 34.2 20.5 64.2 32.7 121.7 3.3 34.7 19.0 52.9 61.1 80.7 163.3 39.4 106.2 60.5 52.5 92.3 5.8 66.9 45.8 51.7 81.2 16.8 68.4 36.7 17.4 14.9 58.3 48.8 17.9 65.7 32.4 136.1 3.9 22.6 34.1 42.8 96.2 46.8 35.9 27.2 24.9 RTCB "C22orf28, FAAP, HSPC117" ENSG00000100220 "RNA 2',3'-cyclic phosphate and 5'-OH ligase" Q9Y3I0 22 32387582-32412248 "Enzymes, Predicted intracellular proteins" "tRNA processing" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000535, HPA001103" Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA 73000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Vesicles, Cytosol" "HPA000535: AB_2666021, HPA001103: AB_1078351" "unprognostic (1.84e-1)" "unprognostic (6.48e-2)" "unprognostic (1.07e-2)" "unprognostic (2.71e-3)" "unprognostic (7.21e-3)" "unprognostic (1.43e-2)" "unprognostic (1.75e-3)" "unprognostic (1.49e-1)" "unprognostic (3.01e-1)" "unprognostic (1.52e-1)" "unprognostic (2.40e-2)" "unprognostic (5.07e-2)" "prognostic favorable (4.25e-5)" "unprognostic (6.91e-2)" "unprognostic (5.35e-2)" "unprognostic (2.05e-1)" "unprognostic (1.55e-1)" 43.5 44.5 33.3 39.0 36.0 31.4 51.2 37.5 40.8 37.7 35.6 56.1 93.9 43.9 43.7 49.4 46.5 32.6 45.8 33.5 38.1 75.9 75.2 36.3 45.6 36.7 37.0 45.6 45.8 73.0 39.8 45.5 39.1 45.9 73.8 44.1 47.2 47.4 71.1 76.9 79.1 56.0 38.3 43.7 48.4 32.0 36.3 72.9 41.5 63.6 87.9 53.9 39.2 40.2 116.1 101.9 125.0 94.3 106.8 79.1 99.3 98.8 118.5 154.6 145.9 133.2 45.9 28.5 64.6 116.1 95.2 76.7 144.7 143.5 198.6 144.3 144.8 81.4 83.0 122.1 73.4 192.4 71.2 78.3 93.7 153.3 147.8 85.1 141.3 78.5 98.2 78.7 114.3 96.4 82.5 66.4 71.7 133.4 91.7 126.0 134.7 147.1 106.0 99.0 128.3 71.1 107.2 68.5 129.2 130.6 75.5 73.8 107.3 84.8 124.8 74.7 96.5 54.4 46.6 102.1 87.8 85.6 113.4 112.5 135.3 89.2 93.0 151.3 104.4 143.5 96.6 97.4 161.4 150.4 114.8 99.1 13.2 125.7 118.7 90.4 131.7 156.3 33.3 36.0 37.5 40.8 33.5 38.1 36.7 37.0 39.1 38.3 36.3 40.2 32.0 32.1 33.4 15.3 40.3 60.5 54.9 84.9 47.8 51.6 35.4 27.6 35.8 47.1 60.6 35.0 20.9 112.6 43.0 74.8 66.5 108.4 4.8 46.3 28.6 45.4 46.7 36.4 22.4 95.6 87.9 35.8 45.9 53.8 42.6 50.5 41.0 58.3 85.4 52.2 19.6 62.2 116.0 47.4 45.9 10.8 35.1 43.2 30.2 25.3 80.0 66.9 34.0 28.6 35.1 106.5 62.1 47.8 36.0 64.3 178.2 146.9 48.2 56.9 26.3 35.4 43.0 67.0 65.1 52.7 76.0 97.8 34.1 59.3 61.3 73.8 RUBCN "KIAA0226, rubicon, rundataxin" ENSG00000145016 "Rubicon autophagy regulator" Q92622 3 197668867-197749727 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Autophagy, Endocytosis, Immunity, Phagocytosis" Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 67.5;Plasma cells: 48.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Karpas-707: 87.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050908, HPA054497" Approved Supported Vesicles,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Vesicles, Cytosol" "HPA050908: , HPA054497: AB_2682507" "unprognostic (2.91e-2)" "unprognostic (1.61e-2)" "prognostic unfavorable (6.65e-4)" "unprognostic (1.34e-3)" "unprognostic (1.46e-1)" "unprognostic (1.20e-2)" "prognostic unfavorable (9.91e-5)" "unprognostic (1.99e-1)" "unprognostic (6.71e-2)" "unprognostic (2.86e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (1.62e-4)" "unprognostic (2.22e-2)" "unprognostic (2.92e-2)" "unprognostic (1.75e-1)" "unprognostic (2.43e-1)" "unprognostic (1.23e-1)" 8.3 7.5 16.2 11.6 16.3 8.5 7.2 10.5 17.0 9.2 4.4 10.4 7.3 8.8 4.0 12.0 8.5 7.2 11.4 17.0 19.0 7.7 5.6 11.8 15.3 20.0 17.8 10.7 9.1 6.8 15.8 5.8 15.9 7.4 5.7 10.9 7.3 7.2 8.9 9.1 13.1 7.8 14.5 19.2 8.1 14.6 23.7 8.8 7.1 8.1 16.1 8.9 8.4 17.4 30.9 7.4 8.2 16.2 14.4 8.3 8.6 13.8 9.2 17.0 14.2 12.7 8.4 33.6 26.7 15.8 16.1 17.0 15.0 8.0 13.6 9.3 13.9 21.6 13.4 4.9 8.4 12.0 18.0 7.0 9.6 14.8 17.6 7.9 10.7 14.4 12.3 87.7 11.5 24.4 15.7 7.5 7.1 8.8 23.2 14.9 8.6 22.6 9.6 13.9 34.3 7.9 10.2 19.8 10.8 5.5 29.2 8.1 13.7 9.9 9.9 27.8 18.9 36.5 34.2 27.0 13.6 22.4 8.7 0.8 2.6 17.5 3.7 3.9 2.4 7.7 3.1 4.7 1.6 8.5 2.2 3.2 2.9 1.8 4.8 16.6 4.4 1.7 16.2 16.3 10.5 17.0 17.0 19.0 20.0 17.8 15.9 14.5 23.7 17.4 8.5 6.4 11.2 0.0 33.9 0.0 6.0 0.0 8.0 21.0 7.3 7.0 0.0 7.2 4.3 12.9 18.8 1.8 28.9 3.8 1.9 5.8 21.7 4.8 6.2 6.7 0.0 5.7 0.0 6.4 3.7 4.8 7.1 9.8 2.5 6.1 9.3 3.5 9.2 21.9 0.0 3.7 0.0 16.3 0.0 16.4 5.0 18.7 0.0 0.0 67.5 15.0 14.4 0.0 0.0 8.5 1.5 6.4 48.3 8.9 5.8 2.7 0.7 14.3 6.6 9.7 6.8 34.1 21.3 5.6 0.0 6.4 15.9 4.9 2.8 12.3 RUFY1 "FLJ22251, RABIP4, ZFYVE12" ENSG00000176783 "RUN and FYVE domain containing 1" Q96T51 5 179550554-179610012 "Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Macrophages: 137.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038804 Approved Supported "Nuclear speckles,Vesicles,Cytosol" NA NA 25000 "Cluster 41: Basophils - Cellular respiration" "Cluster 72: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" "Vesicles, Cytosol" "Nuclear speckles" "HPA038804: AB_10673290" "unprognostic (3.17e-2)" "unprognostic (2.82e-1)" "unprognostic (9.24e-2)" "unprognostic (2.50e-1)" "unprognostic (1.26e-1)" "unprognostic (1.96e-1)" "unprognostic (2.04e-2)" "unprognostic (1.06e-1)" "unprognostic (1.74e-1)" "unprognostic (1.21e-1)" "unprognostic (9.74e-2)" "unprognostic (1.31e-1)" "unprognostic (2.73e-2)" "unprognostic (3.60e-1)" "unprognostic (2.08e-1)" "unprognostic (2.55e-1)" "unprognostic (5.85e-2)" 28.2 33.1 9.6 13.4 10.5 13.3 26.1 9.8 10.2 27.2 11.3 29.1 9.4 27.5 8.1 33.9 24.5 8.8 20.4 9.5 10.1 24.1 21.3 26.6 14.2 10.2 10.0 23.9 24.4 13.5 22.7 9.0 10.1 22.4 8.2 7.4 25.8 8.6 33.8 33.1 25.9 7.8 9.9 35.2 24.2 10.9 10.0 13.6 24.7 10.1 11.5 26.3 27.2 10.6 13.9 22.5 11.8 15.7 22.3 18.2 13.4 24.2 17.2 14.1 16.3 22.0 31.6 22.4 13.4 29.6 16.2 12.6 21.9 31.6 16.4 71.2 16.6 39.2 17.1 16.0 22.8 22.0 20.7 18.5 17.1 9.5 27.0 24.6 15.5 12.5 16.2 20.8 12.7 42.0 23.5 15.2 12.6 15.0 10.5 20.9 8.4 20.9 23.5 22.4 11.7 16.7 35.4 22.5 13.2 14.8 18.0 26.6 18.8 18.3 6.2 10.0 19.3 12.8 21.2 39.8 16.9 39.0 17.2 14.9 4.8 11.9 2.2 5.1 1.3 3.8 2.7 2.3 4.2 5.7 1.9 2.4 7.9 1.8 7.1 4.8 4.5 29.8 9.6 10.5 9.8 10.2 9.5 10.1 10.2 10.0 10.1 9.9 10.0 10.6 19.8 35.3 30.8 30.0 23.6 10.3 11.5 11.7 16.5 9.3 17.8 17.5 22.8 28.6 23.1 14.7 20.9 21.7 15.7 20.0 9.8 19.7 8.0 28.2 21.9 20.9 10.8 27.7 31.8 14.4 15.8 19.7 19.9 20.0 29.8 20.4 12.5 14.1 31.1 11.8 28.4 17.5 8.2 30.7 21.0 3.4 23.0 137.2 10.6 21.5 43.7 11.9 15.5 23.1 33.9 22.1 18.5 27.1 18.3 14.2 14.1 34.0 32.8 12.0 6.6 20.8 17.8 11.1 8.4 21.9 11.4 21.2 19.5 25.0 15.3 10.2 RUNDC3A "RAP2IP, RPIP8" ENSG00000108309 "RUN domain containing 3A" Q59EK9 17 44308413-44318670 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 208.4;pituitary gland: 98.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 55.4;Early spermatids: 24.4;Enteroendocrine cells: 39.0;Excitatory neurons: 46.1;Horizontal cells: 32.0;Inhibitory neurons: 30.4;Late spermatids: 83.4" "Group enriched" "Detected in many" 5 "glioma: 8.6;pancreatic cancer: 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "SCLC-21H: 62.5;SH-SY5Y: 40.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023548, HPA070733" Enhanced Supported Enhanced Vesicles NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA023548: AB_1856069, HPA070733: AB_2732162" "unprognostic (3.66e-2)" "unprognostic (3.77e-2)" "unprognostic (3.50e-3)" "unprognostic (1.58e-3)" "unprognostic (3.04e-1)" "unprognostic (2.02e-1)" "unprognostic (3.87e-3)" "unprognostic (2.29e-1)" "unprognostic (4.63e-2)" "unprognostic (3.43e-2)" "unprognostic (1.42e-3)" "unprognostic (1.34e-1)" "unprognostic (8.87e-3)" "unprognostic (1.07e-2)" "unprognostic (5.17e-2)" "unprognostic (9.39e-2)" "unprognostic (1.84e-1)" 0.3 14.3 149.2 0.4 159.5 2.3 0.3 93.0 208.4 0.2 45.6 3.4 1.2 0.5 0.2 0.8 0.2 0.3 1.8 169.4 105.3 1.8 0.2 0.4 0.2 108.0 106.4 0.8 3.8 3.1 98.3 1.5 108.5 0.8 0.6 31.2 0.3 0.3 0.1 7.9 1.3 0.5 79.2 1.6 2.3 15.2 109.4 0.4 1.4 0.3 0.1 0.2 0.7 135.7 0.0 0.4 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 4.3 0.0 1.4 0.3 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 8.0 0.0 0.2 0.0 0.2 0.0 0.0 0.3 0.0 0.6 0.0 0.9 0.2 0.0 0.5 0.3 0.3 0.1 0.1 1.1 0.3 0.1 62.5 40.3 0.3 0.0 0.3 0.1 0.5 0.8 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 149.2 159.5 93.0 208.4 169.4 105.3 108.0 106.4 108.5 79.2 109.4 135.7 0.1 0.0 0.6 17.3 0.0 0.3 0.3 0.0 0.0 55.4 0.2 0.3 1.1 0.0 0.0 0.0 6.2 0.0 0.0 0.0 3.9 1.3 24.4 0.2 0.3 0.2 39.0 18.7 46.1 3.1 0.0 1.0 0.0 0.2 0.0 0.5 0.4 0.0 0.2 32.0 30.4 0.5 4.1 0.3 0.5 83.4 1.5 0.3 0.0 4.7 0.1 6.5 1.0 16.1 12.5 1.0 1.2 3.4 0.0 0.4 0.0 0.8 0.0 16.8 0.0 0.8 0.5 1.4 1.3 0.0 0.4 0.1 0.1 3.0 0.1 0.3 RUNDC3B "RPIB9, RPIP9" ENSG00000105784 "RUN domain containing 3B" Q96NL0 7 87627548-87832296 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 7.3;brain: 6.3;liver: 5.6" "Group enriched" "Detected in many" 4 "Excitatory neurons: 167.5;Inhibitory neurons: 170.9;Microglial cells: 108.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.2;HEK 293: 1.0;SCLC-21H: 2.7;SH-SY5Y: 1.2;U-138 MG: 1.0;U-266/70: 1.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056968, HPA057155, HPA075760" Uncertain Uncertain Vesicles,Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Vesicles "HPA056968: AB_2683292, HPA057155: AB_2683353, HPA075760: " "unprognostic (2.49e-1)" "unprognostic (1.99e-1)" "unprognostic (2.12e-1)" "unprognostic (1.83e-1)" "unprognostic (2.20e-2)" "unprognostic (1.77e-3)" "unprognostic (1.19e-2)" "unprognostic (4.16e-2)" "unprognostic (2.56e-1)" "unprognostic (1.19e-1)" "unprognostic (9.42e-5)" "unprognostic (4.44e-1)" "prognostic favorable (2.62e-6)" "unprognostic (1.97e-2)" "unprognostic (2.41e-1)" "unprognostic (2.32e-1)" "unprognostic (9.55e-2)" 0.4 7.3 3.1 0.1 2.9 0.0 0.6 6.3 3.9 1.4 0.0 1.3 2.8 1.9 0.6 0.5 1.0 0.9 0.7 2.0 3.7 1.9 5.6 0.4 0.2 2.5 1.5 1.2 0.1 0.3 0.2 0.0 2.2 0.6 1.5 1.7 0.3 0.4 0.1 0.5 2.5 2.1 0.8 0.1 0.1 1.9 4.0 0.1 0.2 0.1 0.2 0.5 0.3 1.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 1.0 0.0 0.5 0.4 0.0 0.5 0.1 0.0 0.2 0.0 0.1 0.0 0.5 0.0 0.5 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.1 2.7 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 1.6 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.1 2.9 6.3 3.9 2.0 3.7 2.5 1.5 2.2 0.8 4.0 1.3 15.3 0.0 0.0 5.5 0.6 4.8 0.1 0.1 2.2 7.9 1.0 1.1 2.5 7.2 0.1 0.0 6.2 0.5 0.9 12.2 1.9 1.1 4.6 5.6 0.5 30.8 0.0 2.7 167.5 0.2 0.8 1.1 0.0 2.0 0.0 0.7 1.4 18.9 0.1 11.8 170.9 2.9 0.0 0.0 2.3 1.7 4.1 0.6 3.6 108.7 0.2 0.7 4.1 15.1 5.7 0.6 6.5 1.5 0.1 0.2 18.2 11.6 0.2 8.0 0.0 0.3 2.0 21.2 18.8 0.4 3.0 1.2 0.8 1.6 4.2 0.1 RUNX1 "AML1, AMLCR1, CBFA2, PEBP2A2" ENSG00000159216 "RUNX family transcription factor 1" Q01196 21 34787801-36004667 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 175.5;Glandular and luminal cells: 155.8;Microglial cells: 195.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 23.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 23.9" "Cell line enhanced" "Detected in many" "HEL: 251.3;HMC-1: 145.3;JURKAT: 226.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA004176, HPA037912" Enhanced Enhanced Nucleoplasm,Vesicles No No "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm Vesicles "HPA004176: AB_1078412, HPA037912: AB_2675733" "unprognostic (4.06e-3)" "unprognostic (2.35e-2)" "unprognostic (1.42e-2)" "unprognostic (1.52e-1)" "unprognostic (5.15e-3)" "unprognostic (2.62e-1)" "unprognostic (5.87e-2)" "unprognostic (1.15e-1)" "unprognostic (1.13e-1)" "unprognostic (1.12e-3)" "unprognostic (2.33e-2)" "unprognostic (3.47e-2)" "prognostic unfavorable (3.44e-15)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (6.17e-2)" "unprognostic (5.47e-2)" 14.8 3.8 2.9 20.3 2.1 45.5 27.1 2.6 4.0 15.3 5.1 6.7 5.1 3.3 3.1 9.2 4.7 16.0 6.3 2.8 3.2 4.6 7.0 22.4 11.3 6.0 4.3 6.3 4.0 1.5 5.1 8.5 6.5 13.5 6.5 0.3 39.2 3.5 18.9 11.6 6.8 9.2 4.9 10.2 16.9 3.8 9.1 28.2 4.8 1.4 9.9 20.8 12.8 7.9 50.9 3.8 0.1 0.3 12.5 16.0 32.0 28.1 28.4 15.3 11.6 2.5 37.7 24.9 1.8 24.9 25.5 45.0 3.0 33.6 21.4 38.7 3.8 251.3 10.1 11.6 22.9 29.4 145.3 30.9 19.8 46.6 45.6 21.2 8.8 226.3 17.3 14.1 32.7 10.7 119.3 46.5 2.2 27.4 14.5 119.2 84.6 15.3 20.7 19.9 1.4 0.0 28.9 7.2 10.5 6.8 14.7 67.8 37.0 25.1 32.4 37.8 42.8 46.4 20.7 23.3 31.2 63.4 37.4 23.9 3.1 7.1 3.4 1.4 3.2 4.1 3.0 3.2 0.9 3.6 4.5 3.7 3.4 1.5 4.7 3.4 4.5 2.2 2.9 2.1 2.6 4.0 2.8 3.2 6.0 4.3 6.5 4.9 9.1 7.9 6.2 54.5 35.4 1.6 27.0 41.6 52.7 61.2 54.7 2.3 175.5 94.6 3.2 28.6 60.8 20.2 0.0 2.1 39.5 18.7 1.9 39.7 19.4 89.6 21.5 9.2 6.0 47.3 3.5 28.1 21.4 49.2 84.6 155.8 17.7 29.2 4.6 5.4 68.4 0.0 3.2 12.4 28.5 77.0 122.5 27.1 4.7 84.4 28.4 195.8 42.2 0.5 39.1 1.5 1.6 101.0 15.8 4.5 27.7 43.6 8.3 1.6 78.6 0.8 0.0 111.3 51.2 29.0 28.0 53.7 20.2 2.5 41.6 2.7 17.0 75.3 RUNX3 "AML2, CBFA3, PEBP2A3" ENSG00000020633 "RUNX family transcription factor 3" Q13761 1 24899511-24965121 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 68.8;lymphoid tissue: 35.1" "Cell type enhanced" "Detected in many" "dendritic cells: 336.4;Langerhans cells: 133.9;NK-cells: 251.3;Plasma cells: 87.1;T-cells: 215.4" "Cancer enhanced" "Detected in all" "melanoma: 25.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 124.9;Karpas-707: 155.6;SK-MEL-30: 92.4;U-266/70: 54.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA004195, CAB025416, HPA059006" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" Cytosol "CAB025416: , HPA004195: , HPA059006: AB_2683877" "unprognostic (7.75e-3)" "unprognostic (6.51e-3)" "prognostic unfavorable (8.71e-4)" "unprognostic (1.42e-1)" "unprognostic (7.60e-2)" "unprognostic (1.81e-2)" "unprognostic (6.51e-2)" "unprognostic (6.95e-2)" "unprognostic (3.39e-1)" "unprognostic (1.28e-2)" "unprognostic (1.01e-1)" "unprognostic (4.71e-1)" "prognostic unfavorable (5.59e-5)" "unprognostic (1.10e-1)" "unprognostic (4.42e-2)" "unprognostic (3.08e-1)" "unprognostic (1.62e-1)" 3.5 1.4 3.7 21.1 3.6 68.8 3.5 3.8 4.6 19.7 3.7 3.7 5.0 1.6 0.7 2.6 1.6 5.3 1.1 3.6 3.8 1.6 3.7 9.5 34.7 4.7 4.4 0.6 0.9 0.4 0.7 0.9 4.3 1.9 4.2 0.1 4.7 0.8 3.8 11.5 15.0 1.6 4.1 35.1 5.5 2.3 4.3 11.2 1.8 0.7 29.0 6.5 1.5 4.5 0.3 10.4 0.0 0.2 0.0 0.0 0.1 0.8 0.0 0.5 0.0 0.5 0.0 19.3 18.4 16.4 0.1 0.4 11.1 0.0 0.7 124.9 1.9 0.4 1.8 0.1 0.0 4.5 42.8 0.1 0.0 0.0 1.1 0.0 0.0 3.1 0.1 155.6 0.0 0.0 1.5 37.9 0.7 0.0 3.2 0.0 0.1 22.7 0.0 0.5 3.5 0.0 7.3 0.1 92.4 2.9 0.0 25.7 0.0 0.0 1.9 0.0 0.5 54.6 40.4 18.2 0.1 42.0 4.4 0.7 1.1 7.0 21.7 4.5 11.3 6.7 7.9 18.7 1.4 5.7 3.9 14.6 1.3 28.7 7.7 1.5 9.2 5.5 3.7 3.6 3.8 4.6 3.6 3.8 4.7 4.4 4.3 4.1 4.3 4.5 4.4 0.0 3.6 0.0 57.7 7.6 0.8 4.6 2.2 0.0 9.8 11.3 2.4 0.0 1.5 1.8 0.0 0.1 336.4 0.5 0.0 0.2 2.3 1.1 1.2 2.4 0.0 13.7 0.0 0.2 0.1 3.3 13.3 2.3 45.2 0.0 2.2 1.5 4.6 0.0 0.0 0.5 0.0 22.9 133.9 1.0 0.0 55.6 46.2 1.0 51.1 0.0 251.3 0.0 0.1 0.1 0.1 0.7 87.1 1.2 0.0 0.3 0.5 0.0 0.0 3.5 3.6 0.3 4.1 2.3 5.8 0.3 215.4 0.1 0.4 0.4 RUSF1 "C16orf58, FLJ13868" ENSG00000140688 "RUS family member 1" Q96GQ5 16 31489471-31509309 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 5.8;Cytotrophoblasts: 22.3;Extravillous trophoblasts: 21.0;Hofbauer cells: 14.8;Syncytiotrophoblasts: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024406 Uncertain Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoli, Golgi apparatus, Vesicles" "Nucleoplasm, Cytosol" "HPA024406: AB_1845580" "unprognostic (1.46e-2)" "unprognostic (2.52e-2)" "unprognostic (2.25e-2)" "unprognostic (4.22e-1)" "unprognostic (6.21e-2)" "unprognostic (3.05e-2)" "unprognostic (2.44e-1)" "unprognostic (1.01e-1)" "unprognostic (1.13e-1)" "unprognostic (9.89e-2)" "unprognostic (3.20e-1)" "unprognostic (1.58e-1)" "unprognostic (6.34e-3)" "unprognostic (1.14e-1)" "unprognostic (1.22e-1)" "unprognostic (5.69e-2)" "unprognostic (2.24e-2)" 27.1 31.8 19.6 20.0 18.9 21.5 28.8 12.0 21.3 45.4 14.2 29.6 31.3 43.2 20.7 26.5 38.2 23.0 28.5 19.9 19.7 29.5 57.9 25.0 19.8 17.0 16.0 49.6 56.8 46.2 48.4 25.7 18.5 39.1 19.1 22.4 64.8 34.2 9.4 26.9 30.3 25.6 13.8 22.3 39.5 21.4 17.0 18.0 42.0 9.8 15.6 31.8 31.4 17.0 28.6 37.2 22.7 39.7 51.7 34.3 42.3 33.4 56.6 25.5 30.2 11.3 49.1 24.5 69.4 49.8 32.9 39.0 22.9 31.0 11.8 35.8 23.0 24.8 20.6 28.8 74.8 29.4 28.6 41.7 33.1 33.7 68.5 50.2 24.9 38.4 37.3 40.9 25.3 53.9 13.7 19.8 17.8 41.8 24.1 31.1 34.2 74.8 29.3 17.6 24.8 38.2 25.2 65.3 52.8 21.5 56.6 42.9 22.0 44.3 24.7 28.7 22.1 59.0 37.0 18.8 56.7 44.7 62.5 3.1 5.7 7.6 7.8 8.4 7.2 6.7 8.2 7.8 9.7 6.3 7.9 7.0 0.9 9.4 8.1 8.9 9.4 7.2 19.6 18.9 12.0 21.3 19.9 19.7 17.0 16.0 18.5 13.8 17.0 17.0 5.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 22.3 2.6 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 21.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 22.3 0.4 0.0 0.0 0.0 RWDD2A "dJ747H23.2, MGC13523, RWDD2" ENSG00000013392 "RWD domain containing 2A" Q9UIY3 6 83193357-83198935 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 52.3;Spermatocytes: 65.2" "Cancer enhanced" "Detected in all" "prostate cancer: 11.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030105, HPA030106, HPA030107" Uncertain Approved Vesicles NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA030105: AB_10599826, HPA030106: AB_10600896, HPA030107: AB_10601009" "unprognostic (2.51e-3)" "unprognostic (1.25e-1)" "unprognostic (2.48e-2)" "unprognostic (1.33e-1)" "unprognostic (1.19e-3)" "unprognostic (3.99e-2)" "unprognostic (1.01e-1)" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "prognostic favorable (3.82e-5)" "prognostic favorable (1.38e-4)" "unprognostic (1.26e-1)" "unprognostic (2.73e-1)" "unprognostic (1.91e-2)" "unprognostic (2.57e-2)" "unprognostic (1.85e-3)" "unprognostic (2.59e-2)" 2.9 6.9 7.1 2.1 7.0 0.5 3.2 6.1 8.1 3.4 6.3 2.9 2.5 3.3 9.4 1.7 3.8 4.6 4.4 6.9 7.9 4.5 5.9 2.8 2.5 5.6 6.0 4.0 9.6 4.0 5.6 2.5 5.9 11.5 2.5 4.7 6.0 4.7 2.3 1.9 2.7 3.2 5.7 2.9 3.9 8.9 8.4 1.8 6.2 4.0 2.6 2.6 1.8 6.1 2.1 1.9 4.4 8.3 5.2 3.7 3.0 4.8 10.1 3.5 4.2 2.8 1.1 1.6 3.8 5.8 8.0 2.1 3.7 2.8 5.4 2.0 3.8 1.9 3.0 6.2 8.0 0.5 1.5 4.9 4.6 4.4 9.2 11.5 6.6 4.5 3.1 2.8 4.3 3.1 0.7 1.5 1.5 1.9 1.9 2.4 9.1 1.0 7.4 2.4 1.5 5.3 2.9 4.5 4.4 6.3 2.8 2.9 7.1 2.4 1.5 3.5 2.1 6.2 2.7 0.9 2.8 0.8 2.9 0.3 0.9 0.0 1.2 0.8 1.8 1.9 1.7 1.7 1.0 1.0 2.2 2.1 0.3 0.4 2.2 3.5 2.2 1.0 7.1 7.0 6.1 8.1 6.9 7.9 5.6 6.0 5.9 5.7 8.4 6.1 2.4 0.0 6.7 9.8 4.2 3.7 3.6 5.3 3.4 5.6 3.7 3.2 5.4 2.8 3.3 1.8 0.0 7.7 3.9 2.4 5.9 8.9 52.3 4.8 4.5 3.5 5.4 0.4 10.8 9.1 3.3 6.5 3.6 4.0 0.0 7.0 5.0 6.8 5.0 1.7 11.2 6.1 8.2 1.6 2.5 14.8 9.0 2.2 8.8 3.7 3.8 11.0 0.0 13.6 4.5 5.8 2.5 6.0 11.2 8.7 4.1 13.3 4.9 5.0 6.6 7.0 5.2 65.2 10.5 1.2 2.4 5.7 2.9 6.3 3.4 2.8 RYR1 "CCO, MHS, MHS1, PPP1R137, RYR" ENSG00000196218 "Ryanodine receptor 1" P21817 19 38433691-38587564 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Developmental protein, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skeletal muscle: 1618.9" "Cell type enhanced" "Detected in many" "Astrocytes: 29.4;Basal squamous epithelial cells: 22.8;Microglial cells: 49.6;Muller glia cells: 50.6;Skeletal myocytes: 41.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "intermediate monocyte: 1.8;myeloid DC: 2.9;non-classical monocyte: 3.8" "Group enriched" "Detected in many" 8 "dendritic cells: 2.9;monocytes: 3.8" "Cell line enhanced" "Detected in some" "A549: 7.7;HaCaT: 18.9;hTCEpi: 7.6;RH-30: 15.3;SiHa: 30.7;U-2 OS: 12.4" "Low region specificity" "Detected in single" HPA056416 Enhanced Approved "Golgi apparatus,Vesicles,Cytosol" NA NA 46000 "Cluster 51: Monocytes - Innate immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 37: Myocytes - Muscle contraction" "Golgi apparatus, Vesicles" Cytosol "HPA056416: AB_2683121" "unprognostic (2.22e-3)" "unprognostic (1.91e-3)" "unprognostic (9.59e-2)" "unprognostic (5.34e-4)" "unprognostic (2.50e-1)" "unprognostic (6.00e-2)" "unprognostic (2.11e-1)" "unprognostic (1.06e-1)" "unprognostic (1.18e-1)" "unprognostic (3.20e-3)" "unprognostic (3.52e-1)" "unprognostic (2.35e-1)" "unprognostic (1.07e-5)" "unprognostic (1.13e-2)" "unprognostic (8.10e-2)" "unprognostic (6.62e-3)" "unprognostic (1.34e-1)" 1.4 2.4 10.3 1.6 8.0 0.3 2.1 8.5 9.3 2.1 1.0 1.2 0.5 0.7 1.3 17.2 1.7 1.1 0.9 7.5 20.5 1.9 0.4 2.6 2.1 8.6 9.7 0.9 0.4 1.9 1.5 1.8 7.7 3.8 0.3 10.6 14.0 1.4 1618.9 13.3 1.3 0.8 2.6 1.7 1.0 8.9 22.6 1.5 1.2 286.6 2.6 1.0 3.3 6.1 0.0 7.7 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 2.8 0.4 0.5 6.3 0.0 0.0 18.9 0.2 0.0 0.0 0.0 0.4 1.5 0.0 0.0 0.0 0.0 0.6 1.7 7.6 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.0 0.0 0.5 1.0 0.0 0.0 15.3 1.5 0.8 0.0 0.0 1.5 30.7 0.0 0.0 0.6 0.7 5.9 0.0 0.0 12.4 0.3 0.0 0.4 1.4 0.4 0.1 0.0 0.0 0.0 0.3 0.0 0.2 1.8 0.2 0.2 0.1 0.3 2.9 0.3 0.0 0.0 0.0 0.0 3.8 0.0 0.4 0.3 10.3 8.0 8.5 9.3 7.5 20.5 8.6 9.7 7.7 2.6 22.6 6.1 0.3 0.0 1.1 29.4 1.4 11.3 3.8 6.6 22.8 8.9 0.5 7.9 3.6 0.0 1.1 0.0 2.1 0.2 1.2 0.0 5.9 0.1 6.7 0.2 0.9 1.0 0.0 0.4 10.2 0.0 0.4 0.9 0.0 0.5 0.0 0.3 0.7 0.0 8.8 1.7 17.2 0.0 2.0 2.9 15.2 5.9 3.1 6.2 0.0 49.6 1.3 50.6 0.0 13.6 2.0 0.0 0.0 1.9 0.9 0.8 0.0 0.2 0.4 1.8 0.0 41.7 1.2 6.3 7.4 7.5 4.7 0.3 2.6 0.4 0.0 0.7 RYR3 ENSG00000198838 "Ryanodine receptor 3" Q15413 15 33310962-33866121 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.7;choroid plexus: 33.3;skeletal muscle: 24.2;tongue: 44.2" "Cell type enriched" "Detected in many" 4 "Astrocytes: 788.8" "Cancer enriched" "Detected in single" 4 "glioma: 1.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "basophil: 1.9" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.9" "Cell line enhanced" "Detected in some" "A549: 4.4;RH-30: 6.5;RPTEC TERT1: 3.1;SuSa: 2.8" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 23.4" HPA062004 Approved Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 70: Brain - Nervous system development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA062004: AB_2797267" "unprognostic (5.85e-2)" "unprognostic (1.57e-1)" "unprognostic (5.30e-2)" "unprognostic (1.35e-1)" "unprognostic (1.26e-2)" "unprognostic (8.03e-4)" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (7.85e-2)" "unprognostic (7.10e-2)" "unprognostic (8.25e-3)" "unprognostic (2.36e-1)" "unprognostic (2.48e-2)" "unprognostic (1.86e-2)" "unprognostic (1.15e-1)" "unprognostic (3.16e-2)" "unprognostic (1.91e-1)" 1.7 0.7 35.2 0.2 43.7 1.4 2.0 33.5 39.7 4.2 33.3 10.1 0.4 7.2 0.1 1.2 5.4 0.5 0.2 35.6 29.3 2.0 0.0 0.3 0.1 35.5 30.2 0.9 0.1 6.1 1.3 0.1 33.5 1.4 1.3 2.2 0.5 2.0 24.2 1.0 1.8 4.4 24.3 0.5 2.1 0.5 37.1 0.6 0.3 44.2 0.4 4.0 2.8 28.8 0.2 4.4 0.9 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 1.1 0.1 0.2 0.4 0.0 1.4 0.1 0.0 0.0 0.0 0.2 0.1 0.9 0.1 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 1.6 0.0 0.2 0.1 0.1 0.7 0.2 0.1 0.3 6.5 0.1 3.1 0.3 0.1 0.3 0.4 0.0 0.1 2.8 0.0 0.2 0.5 0.1 0.1 0.0 0.4 0.2 0.9 0.4 0.3 1.4 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.2 43.7 33.5 39.7 35.6 29.3 35.5 30.2 33.5 24.3 37.1 28.8 2.9 0.0 1.1 788.8 0.2 0.4 0.0 0.0 0.0 8.0 0.2 2.5 2.2 0.0 0.6 0.0 0.0 0.6 0.5 0.0 0.0 0.0 15.5 7.7 1.4 1.8 0.0 8.4 162.5 0.0 0.7 0.6 0.0 8.0 14.0 0.2 0.0 0.0 1.0 69.0 115.2 0.0 0.0 0.0 1.0 41.9 0.3 0.3 0.0 36.5 0.6 0.3 0.0 22.1 5.9 0.0 0.0 0.0 0.1 0.0 0.0 0.3 5.9 0.8 0.0 51.3 0.4 0.1 1.5 0.0 0.6 0.1 0.4 2.5 0.0 0.0 S100B S100beta ENSG00000160307 "S100 calcium binding protein B" P04271 21 46598604-46605208 "Cancer-related genes, Candidate cardiovascular disease genes, Predicted intracellular proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 1499.3;choroid plexus: 781.0" "Cell type enhanced" "Detected in many" "Astrocytes: 126.3;Breast myoepithelial cells: 124.8;Granulosa cells: 261.7;Langerhans cells: 206.8;Melanocytes: 99.6;Oligodendrocytes: 332.1" "Group enriched" "Detected in all" 58 "glioma: 463.5;melanoma: 495.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 360.9" "Lineage enriched" "Detected in all" 6 "T-cells: 360.9" "Group enriched" "Detected in some" 7 "SK-MEL-30: 547.1;WM-115: 992.8" "CAB000073, HPA015768, CAB078196" Enhanced Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA 300000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Cytosol" Vesicles "CAB000073: AB_10013383, CAB078196: AB_2665776, HPA015768: AB_1856538" "unprognostic (5.67e-3)" "unprognostic (6.39e-3)" "unprognostic (2.08e-3)" "unprognostic (2.08e-2)" "unprognostic (4.54e-3)" "unprognostic (1.10e-2)" "unprognostic (1.01e-1)" "unprognostic (6.68e-3)" "unprognostic (2.03e-1)" "unprognostic (1.37e-1)" "unprognostic (8.57e-3)" "unprognostic (6.70e-2)" "unprognostic (4.41e-7)" "unprognostic (3.55e-2)" "unprognostic (7.56e-2)" "unprognostic (1.07e-1)" "unprognostic (1.74e-1)" 151.1 25.7 877.1 10.5 1072.5 2.3 87.0 1254.5 1191.2 28.6 781.0 121.0 7.4 2.4 12.1 14.6 6.9 14.3 28.1 858.4 989.0 3.6 3.2 6.4 21.4 1491.0 1054.2 5.6 5.0 0.3 44.7 0.8 1359.0 29.3 14.2 14.1 19.3 26.2 3.6 15.8 36.3 6.8 1162.2 26.2 23.6 2.4 998.8 18.4 5.2 6.4 20.3 15.9 26.9 1499.3 0.5 0.0 110.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.5 0.9 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.2 15.9 0.6 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.3 2.5 0.0 0.0 547.1 0.0 0.1 0.5 0.0 0.3 0.3 0.0 3.2 0.0 0.3 0.0 1.4 6.7 992.8 0.1 0.5 0.2 360.9 9.5 103.3 0.2 1.0 67.6 16.3 1.4 3.2 153.1 3.2 58.7 10.1 3.9 0.0 63.6 877.1 1072.5 1254.5 1191.2 858.4 989.0 1491.0 1054.2 1359.0 1162.2 998.8 1499.3 4.5 3.2 4.8 126.3 4.6 16.8 0.7 0.0 17.6 1.3 41.2 124.8 6.0 0.0 0.0 0.0 0.0 0.0 14.7 0.1 0.0 0.1 0.4 0.1 0.1 2.7 0.0 2.7 0.9 0.0 0.1 4.4 0.5 0.2 0.0 261.7 4.6 0.4 9.3 0.0 1.4 0.0 0.0 38.6 206.8 1.7 5.6 37.0 99.6 9.4 33.3 25.7 63.8 83.4 332.1 0.1 0.0 0.0 2.2 0.1 0.0 0.1 0.0 4.7 0.0 5.6 7.8 0.1 0.1 0.7 12.6 0.1 37.9 0.0 0.2 0.4 S1PR1 "CD363, D1S3362, edg-1, EDG1" ENSG00000170989 "Sphingosine-1-phosphate receptor 1" P21453 1 101236865-101243713 "Cancer-related genes, CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 236.1;Endothelial cells: 122.3;Hepatic stellate cells: 114.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1248.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ: 73.0;HUVEC TERT2: 198.9;TIME: 113.3;U-251 MG: 147.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010104, HPA075568" Supported Supported Vesicles No NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "CAB010104: AB_2238920, HPA075568: AB_2686758" "unprognostic (1.41e-1)" "unprognostic (9.35e-2)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (9.78e-2)" "unprognostic (4.49e-3)" "unprognostic (1.34e-3)" "unprognostic (1.99e-1)" "unprognostic (1.36e-1)" "unprognostic (9.12e-2)" "unprognostic (2.34e-2)" "unprognostic (2.23e-1)" "unprognostic (5.82e-3)" "unprognostic (2.54e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (8.78e-4)" 114.7 14.4 58.8 29.8 62.7 18.5 91.9 59.8 59.0 18.5 27.8 19.5 9.4 24.7 3.9 26.8 22.9 28.0 71.8 51.3 65.1 18.0 31.3 78.3 46.3 65.2 73.0 8.2 20.3 23.3 8.7 48.1 61.3 13.7 10.1 14.6 15.0 7.8 27.9 17.9 22.3 31.2 57.6 63.1 17.1 2.6 76.5 21.4 35.9 51.5 26.9 34.3 19.2 52.6 15.6 0.2 14.2 0.0 1.4 32.7 0.1 73.0 13.5 47.9 16.6 0.1 0.7 0.0 17.8 25.2 0.4 0.0 1.8 0.8 27.0 6.1 1.2 6.8 0.3 0.0 6.6 0.0 3.5 45.0 0.3 0.1 3.7 1.7 198.9 5.8 0.2 14.4 13.5 0.0 20.6 0.0 3.9 0.4 4.8 0.0 13.4 0.5 0.1 0.0 0.0 0.1 0.7 0.0 0.2 0.9 0.0 0.2 113.3 6.8 2.9 2.0 147.1 1.3 0.0 1.0 0.7 0.0 0.4 1248.4 2.2 55.4 589.4 2.1 441.5 294.7 502.6 492.1 2.6 346.9 383.3 396.3 15.4 397.5 3.4 3.1 329.4 438.7 58.8 62.7 59.8 59.0 51.3 65.1 65.2 73.0 61.3 57.6 76.5 52.6 236.1 0.0 8.9 37.9 36.0 7.6 0.2 0.0 2.2 0.4 1.1 1.1 23.8 2.8 1.3 0.0 0.0 5.9 25.0 0.0 0.0 0.0 0.0 1.1 1.0 122.3 0.0 0.4 0.1 0.0 0.3 11.7 0.5 1.8 7.6 9.7 114.2 8.9 9.9 0.0 0.3 0.0 0.0 6.5 5.7 0.0 0.9 3.0 5.4 13.1 9.9 31.1 40.2 0.5 0.2 0.0 0.0 0.0 18.2 0.5 0.0 0.1 0.0 1.4 0.0 3.6 4.8 0.7 0.7 0.6 5.1 2.6 29.9 1.8 0.1 0.4 SAFB2 KIAA0138 ENSG00000130254 "Scaffold attachment factor B2" Q14151 19 5586999-5624046 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050894 Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles" NA NA 48000 "Cluster 38: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Nuclear bodies, Vesicles" "HPA050894: AB_2681266" "unprognostic (7.46e-2)" "unprognostic (3.09e-1)" "unprognostic (7.69e-3)" "prognostic favorable (7.10e-4)" "unprognostic (7.95e-2)" "unprognostic (6.76e-3)" "unprognostic (4.19e-3)" "unprognostic (5.93e-2)" "unprognostic (2.11e-1)" "unprognostic (5.14e-2)" "prognostic favorable (2.53e-4)" "unprognostic (2.23e-2)" "unprognostic (2.82e-3)" "unprognostic (1.17e-2)" "unprognostic (1.55e-1)" "unprognostic (4.11e-2)" "prognostic favorable (2.12e-4)" 26.8 35.8 23.3 22.4 23.8 35.2 25.8 28.0 30.3 48.4 21.0 35.3 22.2 38.2 21.0 23.1 44.0 15.6 30.8 21.7 29.6 40.6 30.7 27.8 24.4 24.2 23.9 56.2 30.5 18.0 48.6 14.2 23.1 43.0 16.1 34.7 27.6 18.6 41.5 25.8 34.3 19.3 17.5 39.9 27.8 32.5 23.9 22.3 38.9 20.4 21.2 31.5 35.0 27.5 44.9 54.8 38.8 30.4 36.7 23.7 47.6 40.9 21.3 24.4 23.3 69.9 31.4 84.9 36.9 19.9 19.6 39.9 47.2 24.9 39.2 59.8 53.5 64.4 59.5 54.6 21.2 53.0 58.2 23.5 25.4 35.2 26.9 23.9 24.6 29.3 63.6 40.6 28.7 48.9 65.7 53.1 69.9 33.1 59.9 82.2 34.2 47.6 27.7 70.5 37.6 35.3 54.7 25.3 35.3 24.4 36.5 33.0 40.5 30.7 32.7 39.3 57.6 55.2 52.2 58.6 31.2 47.1 52.2 42.8 12.6 22.0 14.6 10.8 16.8 13.9 13.2 11.7 11.3 14.9 14.5 11.7 23.4 9.4 12.3 12.5 13.4 7.9 23.3 23.8 28.0 30.3 21.7 29.6 24.2 23.9 23.1 17.5 23.9 27.5 40.6 41.7 45.1 79.7 69.7 46.7 58.1 41.4 47.3 70.2 39.1 30.6 28.7 20.0 39.3 33.1 75.0 46.8 63.0 46.4 23.5 49.7 7.6 44.5 92.6 49.0 43.0 45.8 36.2 44.4 44.7 47.3 44.4 58.3 42.3 45.4 26.7 23.3 30.6 43.7 42.7 46.5 57.0 27.6 49.5 13.3 72.4 46.6 26.6 32.8 52.2 77.5 52.5 29.7 34.6 42.2 48.6 65.8 70.0 50.3 54.1 61.5 55.3 78.4 46.0 75.4 47.9 68.3 78.8 37.3 41.9 32.3 79.1 59.7 44.8 54.2 SALL2 "Hsal2, KIAA0360, ZNF795" ENSG00000165821 "Spalt like transcription factor 2" Q9Y467 14 21521080-21537216 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.1" "Cell type enhanced" "Detected in many" "Astrocytes: 13.4;Bipolar cells: 13.9;Horizontal cells: 13.5;Muller glia cells: 11.2;Oligodendrocyte precursor cells: 10.6" "Cancer enhanced" "Detected in many" "glioma: 16.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 109.2;NTERA-2: 85.7;SuSa: 36.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004162 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Vesicles Nucleoplasm "HPA004162: AB_2667155" "unprognostic (5.73e-2)" "unprognostic (7.88e-2)" "unprognostic (3.21e-2)" "prognostic unfavorable (3.97e-4)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (5.53e-2)" "unprognostic (4.58e-3)" "unprognostic (1.03e-1)" "unprognostic (1.15e-1)" "prognostic favorable (1.23e-4)" "unprognostic (7.98e-2)" "unprognostic (2.09e-1)" "unprognostic (5.28e-3)" "unprognostic (2.03e-1)" "unprognostic (3.75e-2)" "unprognostic (1.86e-1)" 3.9 5.4 40.2 1.4 37.7 0.2 5.5 43.2 31.0 13.1 16.6 13.3 1.7 13.5 6.3 2.9 12.7 3.2 5.4 29.4 43.7 6.2 0.9 4.5 1.7 41.3 45.2 17.2 4.3 20.6 27.0 1.2 36.9 7.0 2.1 16.9 3.1 9.2 1.5 2.6 6.7 9.5 39.2 2.8 6.0 1.6 49.1 6.5 10.5 2.8 1.7 8.7 6.3 28.7 0.1 2.4 109.2 24.2 1.9 1.6 0.0 2.1 2.7 7.1 7.2 2.3 1.2 0.1 2.2 3.2 3.1 0.2 24.5 2.7 10.0 2.0 12.5 0.0 0.7 2.2 3.2 0.0 0.1 7.3 0.9 3.4 0.0 18.4 2.2 10.9 16.6 0.0 6.2 2.1 16.0 0.1 85.7 0.1 0.5 14.3 2.3 0.0 8.3 11.6 30.4 17.3 0.0 0.6 0.3 36.2 9.2 0.2 0.0 0.9 11.5 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.4 0.3 0.0 0.0 0.5 1.1 0.0 0.1 0.0 0.5 0.5 0.1 40.2 37.7 43.2 31.0 29.4 43.7 41.3 45.2 36.9 39.2 49.1 28.7 0.8 3.2 3.6 13.4 0.0 0.6 0.6 1.1 8.0 13.9 3.4 2.8 0.9 2.8 1.5 5.5 8.4 0.1 0.2 0.0 1.9 1.8 0.3 0.5 3.2 1.0 0.0 0.4 2.5 0.0 0.1 3.9 0.0 0.4 0.0 7.2 2.5 0.1 0.1 13.5 9.3 0.0 4.1 0.0 0.3 0.7 5.0 0.2 0.0 0.0 0.0 11.2 0.0 10.6 2.6 0.3 0.0 6.0 0.2 0.4 0.0 0.8 0.0 2.8 0.0 3.9 3.0 0.0 0.5 1.0 0.6 0.1 0.8 3.9 0.0 0.1 SAMD11 MGC45873 ENSG00000187634 "Sterile alpha motif domain containing 11" Q96NU1 1 923923-944575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Rod photoreceptor cells: 266.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "NK-cell: 1.3" "Lineage enriched" "Detected in single" 11 "NK-cells: 1.3" "Cell line enhanced" "Detected in many" "HEK 293: 87.6;HeLa: 142.1;SCLC-21H: 71.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030110 Approved Nucleoplasm,Vesicles NA NA "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles" "HPA030110: " "unprognostic (9.96e-2)" "unprognostic (1.75e-1)" "unprognostic (4.11e-2)" "unprognostic (1.11e-2)" "unprognostic (1.20e-2)" "unprognostic (2.42e-1)" "unprognostic (9.28e-2)" "unprognostic (6.90e-2)" "unprognostic (3.11e-2)" "unprognostic (1.45e-1)" "unprognostic (1.62e-2)" "unprognostic (1.56e-1)" "prognostic unfavorable (3.35e-5)" "unprognostic (3.01e-2)" "unprognostic (1.05e-2)" "unprognostic (3.26e-2)" "unprognostic (1.18e-1)" 3.8 9.0 3.6 3.3 4.5 1.0 1.8 6.0 8.8 7.4 7.2 4.9 5.1 9.6 9.4 1.9 17.6 3.2 13.2 5.6 9.0 19.7 4.3 3.9 2.1 23.4 10.5 3.3 1.4 1.6 27.6 0.3 10.9 16.9 1.1 24.5 2.0 19.5 0.8 0.8 5.4 4.1 8.8 17.1 4.9 4.7 8.3 0.1 4.7 0.3 0.4 14.0 7.9 10.1 0.3 8.0 0.1 7.4 0.4 0.1 2.0 9.2 0.5 0.6 0.3 0.4 2.4 0.0 19.0 26.0 5.1 15.3 8.8 0.0 0.0 0.8 87.6 0.0 142.1 0.4 1.9 0.0 0.9 5.3 0.0 0.1 0.0 12.1 0.0 0.2 3.5 0.0 0.2 8.4 0.0 0.1 3.8 0.5 0.8 0.7 1.4 5.6 1.2 0.0 71.1 20.9 23.8 12.3 0.2 6.1 12.8 0.5 1.4 3.8 14.4 0.2 2.6 1.3 0.0 0.3 5.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 3.6 4.5 6.0 8.8 5.6 9.0 23.4 10.5 10.9 8.8 8.3 10.1 0.1 0.0 1.8 12.1 0.3 0.4 0.1 0.3 0.6 25.5 0.7 0.4 0.9 2.8 1.9 3.7 29.2 0.2 0.1 0.2 0.0 1.0 3.9 20.1 43.9 6.1 26.5 0.0 0.1 0.4 0.9 17.0 2.0 6.4 0.0 3.8 4.6 0.2 0.3 35.3 0.2 1.0 0.0 0.6 0.0 12.1 0.9 0.7 0.0 1.0 0.0 25.8 0.0 0.0 0.1 1.6 2.6 4.1 0.4 2.1 0.0 0.3 0.1 266.9 0.0 0.2 4.1 1.5 26.0 0.1 0.6 0.1 0.6 0.0 0.2 0.3 SAMD5 dJ875H10.1 ENSG00000203727 "Sterile alpha motif domain containing 5" Q5TGI4 6 147508690-147737547 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Bipolar cells: 96.0;Inhibitory neurons: 276.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 16.6;Hep G2: 65.6;K-562: 44.7;RH-30: 29.0;WM-115: 20.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067811 Uncertain Supported Vesicles No No "Cluster 77: Retina - Visual perception" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA067811: AB_2685901" "unprognostic (4.16e-2)" "unprognostic (4.52e-2)" "unprognostic (9.65e-3)" "unprognostic (1.41e-2)" "unprognostic (1.82e-2)" "unprognostic (5.88e-2)" "prognostic unfavorable (2.23e-4)" "unprognostic (2.31e-1)" "unprognostic (1.54e-1)" "unprognostic (1.61e-2)" "unprognostic (8.55e-3)" "unprognostic (3.09e-2)" "unprognostic (5.40e-3)" "unprognostic (1.72e-1)" "unprognostic (4.51e-2)" "unprognostic (9.82e-3)" "unprognostic (1.50e-1)" 0.6 1.8 2.8 1.3 5.6 0.1 4.1 1.0 2.6 1.4 0.1 6.0 3.0 4.2 0.8 8.9 0.9 2.2 1.2 2.7 4.0 7.4 7.5 3.4 0.3 8.7 4.1 0.4 1.3 5.7 3.8 12.2 9.1 1.4 8.1 8.9 2.3 2.4 0.2 1.9 4.4 3.1 0.0 1.4 4.5 7.6 7.2 0.1 2.1 0.1 0.7 1.5 1.9 0.8 11.2 1.4 1.4 2.0 0.0 0.0 0.1 3.6 1.3 0.3 0.2 16.6 0.1 0.6 3.6 0.0 0.6 0.1 0.3 2.5 0.4 0.0 2.0 0.8 1.5 65.6 0.2 0.0 1.3 0.0 0.1 0.3 0.1 0.0 6.8 0.0 44.7 0.6 4.8 0.1 0.0 0.0 0.1 8.4 2.8 0.0 29.0 6.5 0.1 2.3 0.5 0.1 0.9 0.2 2.8 0.3 0.0 0.0 4.9 0.5 1.5 0.5 1.3 0.1 1.1 0.0 0.1 0.1 20.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.8 5.6 1.0 2.6 2.7 4.0 8.7 4.1 9.1 0.0 7.2 0.8 1.7 3.2 5.9 1.3 1.0 1.8 5.6 0.5 2.2 96.0 2.9 23.5 2.6 0.0 0.0 18.4 2.1 0.2 0.0 5.4 9.8 2.2 0.5 1.1 10.7 11.1 16.9 0.0 15.7 0.2 0.3 6.9 19.4 1.8 0.0 7.0 6.1 28.1 0.8 0.0 276.9 11.6 0.0 1.0 1.4 1.3 0.3 0.7 0.0 45.0 0.0 9.2 0.0 5.5 0.9 0.6 3.4 3.4 0.1 3.0 5.2 19.7 0.0 4.0 0.0 3.1 2.0 0.5 0.2 36.4 1.6 0.3 0.5 3.6 25.7 4.2 SAMD9 "C7orf5, FLJ20073, KIAA2004" ENSG00000205413 "Sterile alpha motif domain containing 9" Q5K651 7 93099513-93118023 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 39.1" "Cell type enhanced" "Detected in many" "dendritic cells: 92.7;Distal enterocytes: 104.6;NK-cells: 109.2;Paneth cells: 171.0" "Cancer enhanced" "Detected in all" "head and neck cancer: 28.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 66.7;GAMG: 66.0" "Low region specificity" "Detected in all" "HPA021318, HPA021319" Approved Supported Vesicles,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol Vesicles "HPA021318: AB_2183383, HPA021319: AB_1856554" "unprognostic (3.66e-2)" "unprognostic (5.35e-1)" "unprognostic (8.60e-2)" "prognostic unfavorable (3.14e-4)" "unprognostic (8.96e-2)" "unprognostic (1.38e-1)" "unprognostic (7.48e-2)" "prognostic unfavorable (2.93e-4)" "unprognostic (4.76e-2)" "unprognostic (3.37e-2)" "prognostic unfavorable (8.31e-5)" "unprognostic (6.00e-2)" "prognostic unfavorable (8.40e-7)" "unprognostic (5.91e-2)" "unprognostic (1.37e-2)" "unprognostic (2.18e-2)" "unprognostic (3.64e-1)" 4.1 3.6 1.1 13.2 1.0 9.9 3.5 1.1 1.0 8.0 1.4 11.0 7.5 3.5 2.9 39.1 3.0 7.2 2.4 1.1 1.6 3.2 3.7 7.7 15.8 2.8 1.5 5.8 1.6 1.0 0.9 7.0 2.0 2.0 11.3 0.3 4.3 2.4 0.6 1.9 7.7 4.0 2.9 17.7 10.7 1.0 2.1 20.7 2.0 2.3 15.9 7.0 8.3 2.5 28.5 3.6 1.0 0.2 12.0 15.2 0.3 10.9 45.2 51.0 66.7 0.2 30.9 11.9 16.8 27.1 66.0 32.6 0.1 10.0 17.1 40.5 1.3 17.3 18.0 0.0 5.4 19.5 23.1 6.8 14.1 16.8 4.6 2.8 7.7 13.1 1.2 28.6 10.9 0.1 29.2 15.9 0.1 0.0 7.9 9.5 9.2 13.5 0.3 3.6 4.4 0.4 8.4 3.3 9.1 0.1 1.0 9.5 33.8 11.8 4.2 36.0 6.0 16.9 3.4 10.8 12.3 11.2 12.1 21.8 4.2 15.7 8.3 8.1 7.7 5.6 6.4 7.3 3.6 5.9 6.7 6.1 17.8 8.8 12.8 2.5 8.8 3.2 1.1 1.0 1.1 1.0 1.1 1.6 2.8 1.5 2.0 2.9 2.1 2.5 43.9 9.6 3.7 0.7 53.4 2.3 8.2 40.2 4.0 1.4 4.4 5.1 1.2 5.7 33.7 14.7 0.0 1.9 92.7 104.6 0.0 23.5 0.1 21.1 18.5 29.0 3.0 19.4 0.4 12.3 7.1 14.6 37.8 7.0 43.6 21.8 12.1 1.2 11.5 6.7 1.5 34.9 20.3 29.9 9.6 0.7 15.2 32.7 3.6 21.5 41.6 2.2 109.2 2.0 2.4 50.4 171.0 12.4 35.9 7.0 12.6 2.3 37.5 0.1 13.1 14.4 12.6 0.2 0.0 21.1 1.8 0.4 69.4 25.4 5.6 34.3 SAPCD1 "C6orf26, NG23" ENSG00000228727 "Suppressor APC domain containing 1" Q5SSQ6 6 31762996-31764851 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 28.3" "Cell type enriched" "Detected in single" 15 "Respiratory ciliated cells: 1.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.4;U-2 OS: 1.1;U-937: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071699 Approved "Vesicles,Cell Junctions" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 24: NB-4 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "Cell Junctions" "HPA071699: AB_2686433" "unprognostic (9.25e-4)" "unprognostic (1.32e-1)" "unprognostic (3.41e-2)" "unprognostic (3.28e-1)" "unprognostic (9.34e-2)" "unprognostic (8.02e-4)" "unprognostic (1.63e-2)" "unprognostic (3.80e-2)" "unprognostic (2.01e-1)" "unprognostic (8.16e-3)" "unprognostic (1.56e-2)" "unprognostic (2.25e-1)" "unprognostic (8.15e-10)" "unprognostic (2.65e-2)" "unprognostic (4.45e-1)" "unprognostic (3.57e-1)" "unprognostic (7.98e-5)" 2.7 1.1 0.4 0.0 0.4 0.2 2.5 0.5 0.9 2.4 0.4 3.7 0.0 2.5 0.1 2.5 3.9 0.0 1.2 0.4 0.3 7.4 3.1 2.0 0.6 0.4 0.5 3.8 2.1 0.0 6.1 0.1 0.4 6.0 0.2 1.2 2.3 0.1 1.0 28.3 3.9 0.1 0.4 4.8 2.6 3.6 0.4 0.2 2.2 0.0 0.1 2.5 2.2 0.4 0.4 0.0 0.0 0.2 0.1 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.1 0.1 0.0 0.5 0.0 0.3 0.2 0.0 0.1 0.5 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.3 0.7 0.4 0.2 0.2 0.2 0.5 0.0 0.1 0.7 1.4 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.0 0.2 0.2 0.1 0.0 0.3 0.4 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.7 0.1 0.4 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.5 0.9 0.4 0.3 0.4 0.5 0.4 0.4 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SARS2 "FLJ20450, mtSerRS, SARS, SARSM, SerRSmt, SERS, SYS" ENSG00000104835 "Seryl-tRNA synthetase 2, mitochondrial" Q9NP81 19 38915266-38930763 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 40.1;Late spermatids: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA052730, HPA056957" Approved Uncertain Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Mitochondria" Vesicles "HPA052730: AB_2681929, HPA056957: AB_2683286" "unprognostic (3.20e-3)" "unprognostic (1.17e-1)" "unprognostic (1.38e-1)" "unprognostic (3.53e-3)" "unprognostic (1.08e-1)" "unprognostic (1.88e-3)" "unprognostic (4.38e-3)" "unprognostic (1.22e-1)" "unprognostic (2.57e-2)" "unprognostic (8.62e-3)" "unprognostic (8.36e-2)" "unprognostic (1.67e-1)" "unprognostic (5.62e-3)" "unprognostic (2.50e-2)" "unprognostic (1.82e-1)" "unprognostic (9.24e-2)" "unprognostic (2.69e-2)" 7.3 17.3 4.2 7.2 4.7 9.3 8.2 4.4 6.8 9.7 3.6 10.1 9.3 9.3 2.8 14.3 8.5 5.9 12.4 4.7 4.4 14.6 18.7 6.6 9.8 5.0 4.4 9.8 15.9 7.8 11.9 7.6 5.3 12.2 5.3 2.3 11.3 6.2 16.4 12.3 10.2 5.1 4.2 12.0 11.9 10.7 4.4 7.5 14.4 11.5 6.6 9.4 9.6 5.4 17.6 47.3 15.5 10.7 5.8 13.3 23.7 10.7 12.6 23.1 17.7 36.0 18.4 17.2 16.3 12.5 9.7 13.9 14.7 29.2 5.3 12.7 24.4 33.7 17.7 32.0 15.4 29.1 31.9 20.7 13.5 14.5 7.6 9.5 14.2 26.3 29.9 14.2 10.6 28.4 21.4 20.7 18.5 21.6 8.5 31.2 16.4 18.6 20.5 36.2 29.1 18.1 14.2 32.7 8.9 4.6 21.8 19.1 11.4 13.7 17.7 11.7 15.1 11.0 7.1 13.2 10.9 18.5 13.8 0.0 8.0 1.0 14.2 14.4 11.5 12.0 10.7 14.7 25.2 10.7 7.5 8.6 0.5 14.0 13.7 9.9 13.4 8.9 4.2 4.7 4.4 6.8 4.7 4.4 5.0 4.4 5.3 4.2 4.4 5.4 2.7 6.4 7.9 6.2 8.4 4.2 3.8 8.3 3.4 8.0 7.0 5.3 8.1 7.2 6.8 5.5 8.4 40.1 5.6 8.9 15.6 15.5 15.7 3.6 3.6 3.8 11.4 13.2 6.8 12.7 23.0 4.8 9.7 3.9 5.7 7.4 6.1 10.1 12.9 5.0 6.7 9.2 10.2 6.7 4.2 56.9 4.7 4.8 3.6 1.9 7.7 3.1 5.2 1.5 3.1 8.4 5.6 4.9 10.1 2.6 7.4 10.3 5.1 13.4 0.0 2.7 4.2 1.9 8.2 12.8 4.1 29.1 7.4 10.6 17.8 3.2 SAYSD1 "C6orf64, FLJ11101" ENSG00000112167 "SAYSVFN motif domain containing 1" Q9NPB0 6 39104063-39115186 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 55.5" "Group enriched" "Detected in many" 4 "Early spermatids: 136.1;Late spermatids: 63.2;Spermatocytes: 223.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007959 Approved Supported Vesicles NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 23: Testis - Cell cycle regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA007959: AB_1078359" "unprognostic (2.65e-1)" "unprognostic (1.49e-2)" "unprognostic (2.03e-2)" "unprognostic (2.58e-1)" "unprognostic (3.70e-1)" "unprognostic (2.56e-1)" "unprognostic (9.90e-3)" "unprognostic (1.96e-2)" "unprognostic (6.50e-2)" "unprognostic (1.82e-3)" "unprognostic (5.08e-2)" "unprognostic (9.90e-2)" "unprognostic (2.54e-2)" "unprognostic (1.79e-1)" "unprognostic (9.78e-3)" "unprognostic (2.27e-1)" "unprognostic (2.00e-3)" 8.8 7.9 7.8 6.5 8.4 7.6 10.5 8.3 10.3 8.6 8.0 8.7 9.9 8.4 11.1 7.5 8.6 6.9 8.3 8.2 8.3 9.6 10.1 7.0 10.3 8.0 8.1 8.8 11.1 7.7 6.3 6.7 8.1 9.2 7.8 6.8 12.6 8.2 7.0 7.4 9.4 6.8 8.1 7.5 7.8 55.5 8.1 17.0 8.7 7.0 9.4 7.2 6.9 9.6 14.8 9.4 8.3 9.9 13.4 17.7 8.6 6.7 7.3 7.9 8.3 13.6 10.2 13.4 9.4 8.8 11.2 9.9 7.3 6.3 8.3 8.5 13.2 8.8 5.5 11.9 10.9 10.1 12.7 12.3 15.4 3.1 7.8 5.6 7.4 19.9 15.1 7.9 9.0 20.4 16.1 16.6 7.2 9.7 4.8 2.3 10.1 5.4 16.7 10.3 23.3 9.4 11.6 10.0 10.9 6.6 16.4 13.1 9.7 10.4 7.5 3.2 8.8 0.2 4.3 16.2 6.0 14.4 7.8 10.6 10.8 24.9 14.0 15.1 16.0 16.4 15.2 12.8 11.4 18.5 21.0 17.9 5.2 15.8 15.8 9.0 22.2 12.1 7.8 8.4 8.3 10.3 8.2 8.3 8.0 8.1 8.1 8.1 8.1 9.6 19.3 3.2 6.0 4.6 11.4 15.4 13.2 29.1 8.6 6.4 26.4 21.8 18.8 21.5 17.0 18.4 8.4 33.1 8.3 10.5 17.6 22.9 136.1 22.8 14.0 11.2 8.4 13.5 3.2 21.8 32.7 16.8 4.6 19.0 8.2 13.8 6.4 23.3 26.8 6.7 4.2 16.5 2.0 13.9 15.7 63.2 20.5 13.2 12.4 0.0 11.9 15.5 12.3 9.0 6.3 15.9 9.7 19.2 5.3 22.6 21.8 28.3 19.2 4.1 6.6 13.1 17.3 223.6 14.5 11.6 16.6 12.3 12.8 10.2 20.1 14.9 SBSN "HLAR698, UNQ698" ENSG00000189001 Suprabasin Q6UWP8 19 35523367-35528351 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 1056.2;skin 1: 2444.7;vagina: 756.5" "Cell type enriched" "Detected in some" 11 "Suprabasal keratinocytes: 1017.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 355.2;melanoma: 153.1" "Group enriched" "Detected in some" 5 "basal ganglia: 3.9;cerebral cortex: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 62.2;ASC TERT1: 107.5;HSkMC: 146.1;U-2197: 51.6;U-87 MG: 119.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA062568, HPA067734" Enhanced Approved Vesicles "Secreted - unknown location" NA NA 89000000 "Cluster 31: Skin - Epidermis development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 28: Keratinocytes - Keratinization" Vesicles "HPA062568: AB_2684794, HPA067734: AB_2685894" "unprognostic (1.10e-1)" "unprognostic (1.01e-1)" "unprognostic (2.02e-2)" "unprognostic (1.21e-1)" "unprognostic (1.73e-1)" "unprognostic (1.83e-2)" "unprognostic (1.23e-3)" "unprognostic (3.45e-3)" "unprognostic (2.56e-1)" "unprognostic (4.83e-4)" "unprognostic (4.31e-4)" "unprognostic (6.97e-2)" "unprognostic (9.08e-14)" "unprognostic (6.37e-2)" "unprognostic (6.51e-3)" "unprognostic (2.09e-1)" "unprognostic (1.36e-3)" 2.9 0.6 0.5 0.1 3.9 0.7 94.3 0.4 1.3 465.7 0.3 1.0 0.0 0.5 0.0 1056.2 0.2 0.3 1.4 0.5 0.4 0.4 1.7 0.9 0.0 0.5 0.4 0.7 1.5 0.0 0.9 0.3 0.5 0.5 0.0 0.0 351.8 0.0 13.1 2444.7 0.7 0.2 0.4 0.5 1.1 1.0 0.5 6.5 0.7 0.0 168.9 1.1 756.5 0.4 0.1 0.1 0.0 0.1 62.2 107.5 0.1 5.1 7.2 2.4 0.9 0.0 0.1 0.1 1.2 4.8 1.7 0.3 0.0 1.8 1.0 0.1 0.2 0.0 0.1 0.0 0.6 0.0 0.1 146.1 8.2 30.0 7.1 2.1 0.0 0.0 0.1 0.3 0.0 0.4 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 1.4 0.3 0.2 0.0 0.4 18.4 3.8 51.6 1.4 0.5 0.3 0.0 119.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 3.9 0.4 1.3 0.5 0.4 0.5 0.4 0.5 0.4 0.5 0.4 0.0 0.0 0.0 0.0 0.0 89.3 0.1 0.6 0.0 0.0 0.1 0.1 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 1.4 0.8 1.8 0.0 0.0 0.2 0.6 0.2 3.1 0.0 4.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 25.2 4.0 0.0 0.2 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.0 0.1 1.0 0.2 0.2 13.4 1017.6 0.3 0.7 0.0 0.0 0.4 SBSPON "C8orf84, RPESP" ENSG00000164764 "Somatomedin B and thrombospondin type 1 domain containing" Q8IVN8 8 73064543-73124088 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 36.5;Collecting duct cells: 42.3;Muller glia cells: 48.5;Peritubular cells: 26.7;Smooth muscle cells: 28.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "medulla oblongata: 7.5;pons: 6.3;spinal cord: 7.7;white matter: 16.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "BJ: 9.5;RPTEC TERT1: 16.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA029595 Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 40000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA029595: AB_10600763" "prognostic favorable (7.18e-4)" "unprognostic (5.08e-3)" "unprognostic (3.24e-1)" "unprognostic (4.41e-2)" "unprognostic (1.75e-1)" "unprognostic (2.31e-1)" "unprognostic (2.78e-2)" "unprognostic (8.65e-2)" "unprognostic (2.92e-1)" "unprognostic (1.46e-1)" "unprognostic (9.54e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (8.82e-4)" "unprognostic (6.14e-2)" "unprognostic (3.54e-1)" "unprognostic (2.12e-2)" "unprognostic (6.25e-2)" 6.4 3.0 0.4 1.4 0.5 0.3 3.4 1.2 0.6 5.2 0.6 4.7 0.9 4.4 4.5 9.5 8.2 1.3 2.3 0.8 0.8 8.3 0.6 3.9 1.5 7.5 0.9 3.3 1.2 0.1 1.6 9.4 6.3 15.1 1.1 9.0 4.6 10.8 0.6 1.9 2.5 8.9 7.7 1.1 9.6 2.6 0.4 0.2 2.5 1.4 0.2 17.9 4.7 16.7 0.2 0.2 0.4 0.5 0.0 0.0 1.3 9.5 0.0 0.0 0.0 0.1 0.2 0.4 0.5 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.4 0.3 0.4 0.4 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.3 0.0 0.0 0.4 0.3 0.9 0.5 0.2 0.2 0.1 0.0 16.9 0.1 0.5 0.5 1.0 0.4 0.1 3.1 0.2 0.1 0.5 0.1 1.5 0.2 0.2 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.4 0.5 1.2 0.6 0.8 0.8 7.5 0.9 6.3 7.7 0.4 16.7 0.6 9.6 0.0 1.0 0.2 1.3 6.9 0.0 36.5 2.4 5.8 11.6 3.8 4.3 0.0 42.3 2.1 0.2 1.0 0.5 1.9 1.3 10.3 7.2 1.4 1.7 0.0 0.0 0.5 0.0 0.4 13.2 10.7 14.9 0.0 0.2 1.4 0.2 0.4 0.0 0.4 0.2 0.0 0.0 0.4 3.2 12.2 0.4 3.6 0.0 0.0 48.5 0.0 1.0 0.2 0.6 0.0 26.7 0.0 1.8 0.0 3.6 0.0 2.2 6.6 0.9 28.7 11.4 4.4 0.6 1.3 0.4 0.5 0.2 0.1 0.5 SCAMP1 SCAMP37 ENSG00000085365 "Secretory carrier membrane protein 1" O15126 5 78360611-78480739 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044753, CAB079009" Supported Uncertain "Nucleoplasm,Vesicles,Cell Junctions" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Cell Junctions" "Nucleoplasm, Vesicles" "CAB079009: , HPA044753: " "unprognostic (8.25e-2)" "unprognostic (3.65e-2)" "unprognostic (1.40e-3)" "unprognostic (5.34e-3)" "unprognostic (2.60e-1)" "unprognostic (2.57e-3)" "unprognostic (5.51e-2)" "unprognostic (3.43e-2)" "unprognostic (1.31e-1)" "unprognostic (8.23e-3)" "unprognostic (2.35e-2)" "unprognostic (2.56e-1)" "prognostic favorable (1.92e-4)" "unprognostic (8.44e-3)" "unprognostic (7.56e-2)" "unprognostic (3.12e-2)" "unprognostic (4.99e-2)" 17.9 22.4 18.4 12.7 20.5 8.5 28.2 24.5 29.1 23.9 23.9 19.6 16.0 25.0 23.2 24.7 29.6 20.2 24.7 20.4 22.4 28.6 17.8 17.8 12.1 18.4 21.5 22.8 25.2 47.1 15.7 23.4 21.4 34.3 22.3 40.2 31.5 29.8 10.6 17.7 15.6 26.6 20.0 13.6 27.9 14.1 23.3 14.6 39.8 16.3 13.4 25.0 11.4 19.0 32.7 23.9 23.4 76.1 35.5 45.5 40.8 30.0 46.1 26.5 56.1 9.3 61.1 48.1 31.4 45.5 65.7 26.2 34.9 57.0 45.9 17.4 32.5 20.5 17.8 20.1 22.7 13.6 16.5 28.6 54.5 27.3 41.2 62.5 41.3 25.0 8.4 33.6 50.9 39.2 25.2 26.7 19.9 14.3 26.0 29.5 38.3 55.3 43.5 38.6 70.9 40.6 27.6 38.5 26.7 24.9 52.5 26.1 36.6 26.3 19.3 30.0 24.2 20.9 29.4 27.6 50.1 50.4 22.6 20.3 11.4 13.2 7.5 12.7 9.3 7.6 8.7 9.2 14.8 6.5 7.1 6.3 6.8 10.3 16.6 4.5 9.1 8.0 18.4 20.5 24.5 29.1 20.4 22.4 18.4 21.5 21.4 20.0 23.3 19.0 59.5 25.6 22.4 45.7 20.3 39.1 31.5 33.6 38.7 72.1 33.4 22.7 36.1 21.5 30.4 40.5 70.9 13.8 21.7 19.1 13.7 24.2 42.2 34.9 30.2 31.4 35.4 12.0 80.0 30.5 24.8 34.3 36.7 34.1 12.0 41.7 27.1 15.7 19.2 32.0 100.1 34.2 20.3 33.7 33.1 15.3 20.2 25.1 30.2 45.0 19.1 47.4 19.6 76.4 60.3 29.8 14.9 28.6 23.9 44.6 14.2 24.7 65.4 68.2 13.1 33.5 25.4 25.6 23.1 30.8 45.3 10.5 21.2 30.8 18.8 33.7 SCAMP2 ENSG00000140497 "Secretory carrier membrane protein 2" O15127 15 74843730-74873365 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014699, HPA019194" Approved Supported "Golgi apparatus,Vesicles" NA NA 71000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles" "HPA014699: AB_1856605, HPA019194: AB_1856604" "unprognostic (1.74e-1)" "unprognostic (1.27e-2)" "unprognostic (2.05e-1)" "unprognostic (5.23e-3)" "unprognostic (2.89e-1)" "unprognostic (1.38e-1)" "unprognostic (1.53e-2)" "unprognostic (7.23e-2)" "unprognostic (9.73e-3)" "unprognostic (7.26e-2)" "unprognostic (8.44e-2)" "unprognostic (1.97e-1)" "prognostic favorable (1.12e-6)" "unprognostic (3.40e-1)" "unprognostic (1.79e-2)" "unprognostic (1.19e-2)" "unprognostic (3.10e-2)" 43.1 46.7 27.8 40.3 32.8 51.5 40.7 31.9 31.2 40.5 38.8 76.0 75.7 36.9 36.9 103.4 47.4 35.4 32.4 26.1 29.8 44.9 42.0 49.6 47.9 40.7 30.9 26.5 54.5 85.6 29.4 48.9 36.7 35.5 72.7 4.7 92.7 32.4 34.2 68.3 80.1 33.6 33.6 66.8 64.9 36.2 33.3 33.0 38.3 18.9 53.4 38.1 49.4 35.4 44.7 57.3 24.2 37.6 72.0 37.2 72.0 45.0 56.6 46.9 50.1 83.0 102.6 36.5 57.8 68.1 67.7 157.8 72.3 55.9 19.4 145.8 71.1 92.8 31.2 57.6 54.3 48.0 170.9 48.0 97.6 44.4 32.0 37.0 46.0 42.0 31.3 67.5 33.3 68.1 24.6 55.3 24.1 111.0 36.6 42.6 22.3 126.4 54.0 63.1 24.9 25.0 36.7 64.3 42.4 35.4 88.5 76.3 43.4 40.2 23.9 43.8 53.0 46.1 73.2 37.6 37.8 112.2 30.2 118.3 111.3 90.0 94.1 106.9 76.1 80.8 85.3 95.9 81.8 70.9 69.4 75.8 74.4 83.8 119.3 128.7 105.3 120.8 27.8 32.8 31.9 31.2 26.1 29.8 40.7 30.9 36.7 33.6 33.3 35.4 36.0 73.7 31.7 17.9 49.5 17.5 41.7 40.5 19.4 6.8 28.0 24.8 14.4 24.3 53.1 40.5 2.1 156.9 63.4 116.8 15.6 67.4 132.3 30.8 22.0 36.2 37.3 29.0 7.7 92.8 61.9 37.2 54.0 40.6 79.2 31.3 26.4 27.7 164.7 6.7 6.1 77.5 42.7 78.3 44.5 56.2 32.0 77.0 32.0 21.5 56.9 41.4 63.8 12.1 17.9 96.1 75.5 23.0 73.1 54.0 105.7 48.1 52.6 8.4 26.3 25.6 35.8 47.1 35.3 39.6 22.3 136.4 55.1 40.0 64.2 58.5 SCAMP3 C1orf3 ENSG00000116521 "Secretory carrier membrane protein 3" O14828 1 155255979-155262430 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071167 Supported Vesicles NA NA 75000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA071167: AB_2686352" "unprognostic (4.31e-2)" "unprognostic (1.30e-2)" "unprognostic (1.07e-2)" "unprognostic (2.17e-2)" "unprognostic (5.33e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (2.92e-5)" "unprognostic (8.78e-2)" "unprognostic (1.40e-1)" "unprognostic (1.06e-1)" "unprognostic (2.65e-1)" "unprognostic (3.74e-2)" "unprognostic (8.46e-3)" "unprognostic (1.60e-1)" "unprognostic (4.79e-1)" "unprognostic (1.07e-1)" "unprognostic (7.18e-2)" 45.1 69.6 4.6 7.1 6.8 7.9 43.5 6.3 8.2 38.1 4.5 37.4 7.7 35.2 0.2 49.9 31.9 5.0 65.0 5.0 4.5 49.0 48.4 40.9 12.1 6.3 5.2 34.9 51.9 4.7 33.8 7.3 5.6 37.0 2.4 1.1 49.3 6.1 90.9 56.4 38.4 3.5 6.4 46.5 47.0 28.3 5.4 8.3 38.6 3.2 7.2 39.5 38.6 8.2 19.7 30.2 11.2 8.8 8.3 6.8 14.5 21.6 20.7 26.3 19.4 30.0 15.7 45.1 49.3 10.9 15.7 20.5 9.0 18.7 1.8 29.8 68.3 25.7 11.7 8.5 26.1 30.5 17.4 9.7 20.9 21.2 10.3 3.3 18.9 49.3 38.2 18.3 11.6 38.3 50.5 14.6 16.5 27.9 59.4 43.1 9.1 67.5 4.8 13.1 8.3 20.0 26.2 8.0 39.1 3.4 32.1 13.7 29.0 20.9 17.5 29.3 29.6 43.3 84.8 52.9 16.7 41.1 15.2 41.0 47.5 52.8 94.4 51.7 86.8 98.8 91.3 91.1 58.1 100.3 83.3 86.6 6.7 76.0 71.4 102.4 101.0 100.9 4.6 6.8 6.3 8.2 5.0 4.5 6.3 5.2 5.6 6.4 5.4 8.2 23.0 16.0 37.1 12.4 33.8 38.2 23.8 57.3 54.1 18.5 27.3 19.3 39.1 30.0 43.7 33.1 4.2 86.4 27.2 19.0 9.8 49.0 1.7 16.3 20.8 33.1 30.1 14.5 9.9 69.4 55.1 27.1 27.0 26.3 25.3 16.6 32.9 37.9 57.3 18.5 11.9 24.3 42.7 21.3 26.7 5.3 17.1 23.0 24.9 7.5 41.3 20.2 30.9 9.5 17.4 48.5 19.9 18.8 56.1 24.7 36.8 24.4 22.6 10.9 13.1 16.7 27.3 20.0 5.5 46.7 40.1 71.3 33.4 20.5 30.1 22.5 SCAMP4 FLJ33847 ENSG00000227500 "Secretory carrier membrane protein 4" Q969E2 19 1905372-1926013 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043284 Approved Approved "Golgi apparatus,Vesicles,Lipid droplets,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus, Vesicles" "Lipid droplets, Plasma membrane" "HPA043284: AB_10806501" "unprognostic (1.60e-1)" "unprognostic (3.62e-1)" "unprognostic (5.04e-2)" "prognostic favorable (4.40e-6)" "unprognostic (2.58e-1)" "unprognostic (4.58e-1)" "prognostic unfavorable (1.92e-5)" "unprognostic (2.04e-1)" "unprognostic (1.58e-1)" "unprognostic (2.55e-1)" "unprognostic (3.01e-3)" "unprognostic (5.66e-2)" "prognostic favorable (3.56e-4)" "unprognostic (6.16e-2)" "unprognostic (1.58e-1)" "unprognostic (3.93e-2)" "unprognostic (1.03e-1)" 23.2 27.4 31.1 15.5 39.9 11.4 25.4 41.3 33.3 28.1 33.6 23.3 19.8 26.0 17.5 39.9 38.3 19.5 15.5 28.9 33.1 34.4 28.3 25.5 15.6 51.5 42.9 27.1 36.5 15.8 31.8 18.8 47.7 31.7 9.8 7.4 43.9 20.4 13.9 36.3 20.3 12.3 39.7 25.1 26.4 22.0 40.6 8.3 32.7 5.8 9.4 22.0 25.0 53.5 53.6 53.9 25.7 56.8 50.7 31.7 29.6 35.5 33.1 39.3 46.7 44.9 51.1 22.5 32.1 30.7 23.1 63.7 24.7 38.2 14.5 34.8 21.7 15.8 19.0 44.3 65.6 16.9 23.2 48.8 24.2 34.8 21.2 32.9 27.2 25.2 35.7 25.3 23.3 67.8 21.5 31.6 38.8 31.1 18.6 25.9 18.1 34.6 49.8 47.5 33.8 45.0 23.9 49.9 31.4 18.1 50.6 41.5 29.6 44.8 30.5 81.1 35.7 57.8 62.6 21.0 59.1 26.9 30.1 1.7 4.4 1.9 3.9 4.9 2.0 5.1 2.7 2.6 4.8 3.4 1.5 2.9 2.1 5.8 4.5 12.0 2.3 3.7 31.1 39.9 41.3 33.3 28.9 33.1 51.5 42.9 47.7 39.7 40.6 53.5 16.9 9.6 7.3 12.1 22.9 17.1 25.0 20.8 33.0 19.7 40.0 23.5 3.0 21.5 14.1 49.7 75.0 40.0 59.6 53.0 7.9 20.8 0.8 63.2 23.2 17.8 18.7 11.6 8.3 12.5 38.1 18.2 43.3 42.1 17.2 27.8 15.7 13.4 38.0 21.9 8.0 36.1 20.3 20.1 24.9 1.9 21.8 24.2 21.4 5.6 21.0 29.6 33.0 16.6 18.9 16.1 25.3 17.3 16.0 30.0 47.6 10.1 33.2 52.2 0.0 15.8 15.7 19.0 26.1 30.8 20.2 59.0 20.4 26.9 31.1 28.1 SCARB1 "CD36L1, CLA-1, CLA1, SR-BI, SRB1" ENSG00000073060 "Scavenger receptor class B member 1" Q8WTV0 12 124776856-124882668 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "adrenal gland: 995.8" "Cell type enhanced" "Detected in many" "Adipocytes: 133.9;Granulosa cells: 114.6;Hepatocytes: 159.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 6.2;myeloid DC: 8.9;plasmacytoid DC: 21.0" "Group enriched" "Detected in many" 6 "dendritic cells: 21.0;monocytes: 6.2" "Cell line enhanced" "Detected in many" "RPMI-8226: 148.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066285, CAB070124, HPA072449" Enhanced Approved "Vesicles,Lysosomes,Rods & Rings" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Vesicles "Lysosomes, Rods & Rings" "CAB070124: AB_10107658, HPA066285: AB_2685649, HPA072449: AB_2732201" "unprognostic (9.70e-3)" "unprognostic (4.94e-3)" "unprognostic (1.32e-1)" "unprognostic (4.79e-2)" "unprognostic (1.65e-3)" "unprognostic (4.21e-3)" "prognostic unfavorable (1.83e-5)" "prognostic unfavorable (4.02e-4)" "unprognostic (2.30e-1)" "unprognostic (1.09e-1)" "unprognostic (1.80e-2)" "unprognostic (4.99e-2)" "prognostic unfavorable (1.49e-5)" "unprognostic (3.50e-1)" "unprognostic (1.49e-1)" "unprognostic (1.81e-1)" "unprognostic (4.13e-1)" 59.2 995.8 12.3 4.0 22.7 1.3 55.4 7.2 13.2 12.9 21.7 14.7 12.5 13.7 0.9 9.2 13.1 12.9 10.5 12.3 8.9 6.8 235.7 15.3 6.2 11.0 10.0 54.8 9.6 4.0 15.2 111.5 12.0 13.0 9.2 12.0 21.2 2.3 9.8 26.4 14.9 7.8 7.2 12.7 8.8 19.1 15.5 2.9 11.7 5.0 10.4 12.3 12.7 11.5 30.1 50.0 22.2 51.4 12.3 23.1 0.0 24.2 20.0 21.4 12.1 56.7 61.7 91.6 66.4 12.4 31.1 39.2 58.0 109.3 13.2 45.5 51.4 18.5 53.1 68.3 33.2 35.9 17.2 39.5 19.7 41.0 32.5 36.7 57.2 9.1 41.5 21.5 4.3 27.7 12.9 23.5 22.8 30.7 66.0 51.0 18.8 148.7 0.8 32.9 38.8 12.1 126.5 95.9 70.2 13.3 55.8 29.9 4.6 2.6 23.8 14.3 29.8 10.1 3.8 15.7 11.3 29.0 23.9 0.0 6.2 0.0 0.2 3.0 0.1 2.3 0.0 0.2 8.9 0.9 0.0 0.0 0.8 0.0 0.6 21.0 0.0 3.8 12.3 22.7 7.2 13.2 12.3 8.9 11.0 10.0 12.0 7.2 15.5 11.5 133.9 3.2 2.7 25.8 8.6 5.6 3.6 9.0 6.8 6.1 14.8 17.0 6.5 8.6 5.3 3.7 29.2 10.7 10.5 46.7 3.9 5.4 18.1 1.0 5.3 44.2 10.7 8.2 21.0 7.4 13.8 7.9 11.7 3.4 1.3 114.6 21.4 159.4 51.6 16.8 24.8 13.1 8.2 14.8 11.4 12.6 9.0 16.7 48.0 74.9 5.9 52.9 0.0 23.1 27.3 5.8 12.9 5.3 8.0 9.9 10.0 2.9 4.7 7.5 0.0 3.1 5.0 25.0 1.6 6.5 3.1 43.4 1.8 60.0 9.4 4.4 SCCPDH "CGI-49, NET11" ENSG00000143653 "Saccharopine dehydrogenase (putative)" Q8NBX0 1 246724409-246768137 "Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 159.5" "Group enriched" "Detected in all" 4 "Early spermatids: 1380.7;Spermatocytes: 822.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 20 "basophil: 872.9" "Lineage enriched" "Detected in all" 26 "granulocytes: 872.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050775, HPA076030" Enhanced Approved Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA050775: AB_2681231, HPA076030: " "unprognostic (4.25e-1)" "unprognostic (3.11e-1)" "unprognostic (1.22e-1)" "unprognostic (1.75e-2)" "unprognostic (2.83e-2)" "unprognostic (6.43e-2)" "unprognostic (1.25e-1)" "unprognostic (1.10e-1)" "unprognostic (1.60e-1)" "unprognostic (5.51e-2)" "unprognostic (1.93e-1)" "unprognostic (3.60e-1)" "unprognostic (2.70e-2)" "unprognostic (9.63e-2)" "unprognostic (1.13e-1)" "unprognostic (2.24e-1)" "unprognostic (3.93e-2)" 26.6 53.7 35.1 14.4 45.5 35.7 23.6 51.5 43.2 22.6 40.8 27.2 34.4 26.2 17.6 9.3 31.6 21.6 32.8 35.3 45.4 49.8 158.2 21.0 13.5 64.0 45.2 22.4 18.8 36.5 24.3 23.8 64.3 39.4 26.8 31.7 15.3 26.0 60.7 24.1 34.6 24.0 57.0 11.5 28.0 159.5 47.3 20.1 33.5 54.7 10.6 81.5 12.0 86.8 55.3 53.2 37.7 22.8 44.5 55.7 0.5 42.3 58.8 70.1 58.3 32.7 150.6 29.3 53.8 49.0 38.9 17.7 32.4 12.6 71.6 40.8 11.9 49.6 46.9 65.9 41.6 97.1 40.7 37.6 5.9 47.4 4.8 65.7 76.4 60.0 62.9 0.1 70.9 13.5 101.6 122.6 56.5 29.6 41.7 83.8 48.5 0.3 216.6 128.2 42.7 48.0 57.3 2.5 39.0 20.2 42.1 99.6 49.8 32.1 28.5 78.7 110.5 138.0 51.1 17.4 54.7 130.2 43.3 872.9 24.3 44.1 18.1 22.2 22.4 11.2 5.4 15.7 10.7 9.4 7.1 22.0 6.4 34.1 15.4 18.2 4.0 17.1 35.1 45.5 51.5 43.2 35.3 45.4 64.0 45.2 64.3 57.0 47.3 86.8 25.0 6.4 11.5 25.8 8.0 30.1 40.6 54.6 1.8 31.2 42.4 17.5 38.0 55.8 40.5 152.6 18.8 41.4 14.6 42.4 31.3 67.2 1380.7 72.7 39.4 23.6 44.9 54.7 23.7 69.0 17.4 35.7 32.6 111.9 57.2 49.2 22.5 187.8 89.4 6.7 20.5 27.4 52.9 45.7 13.7 245.6 47.5 29.7 48.0 10.3 20.3 67.4 18.6 27.2 37.3 75.2 27.8 47.4 8.3 49.2 138.4 69.7 79.4 39.2 19.7 36.7 39.4 822.3 76.2 5.6 68.5 84.6 17.0 42.8 55.0 201.9 SCG2 "CHGC, SgII, SN" ENSG00000171951 "Secretogranin II" P13521 2 223596940-223602361 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 360.1;brain: 426.2;pituitary gland: 269.0" "Group enriched" "Detected in some" 5 "Bipolar cells: 212.4;Enteroendocrine cells: 283.4;Inhibitory neurons: 109.9;Ionocytes: 138.4" "Group enriched" "Detected in many" 8 "glioma: 70.0;pancreatic cancer: 52.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 53.3;HSkMC: 45.9;hTERT-RPE1: 46.5;SCLC-21H: 47.6;SH-SY5Y: 20.7;WM-115: 35.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011893, HPA075062" Enhanced Supported Approved "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 330000 "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Golgi apparatus" Vesicles "HPA011893: AB_1856656, HPA075062: AB_2732277" "unprognostic (2.93e-2)" "unprognostic (1.44e-2)" "unprognostic (1.23e-3)" "unprognostic (6.82e-4)" "unprognostic (2.51e-2)" "unprognostic (1.13e-2)" "unprognostic (2.77e-3)" "unprognostic (6.73e-2)" "unprognostic (1.08e-1)" "unprognostic (4.69e-2)" "prognostic favorable (5.58e-4)" "unprognostic (1.34e-1)" "prognostic unfavorable (7.01e-10)" "unprognostic (2.47e-3)" "unprognostic (4.02e-1)" "unprognostic (1.57e-2)" "unprognostic (1.90e-3)" 9.2 360.1 49.2 30.2 78.4 0.4 0.5 17.1 54.7 1.5 2.2 10.6 47.7 3.5 0.4 0.6 0.2 4.0 1.7 21.7 426.2 0.6 0.2 3.3 0.4 118.3 195.4 6.1 28.3 0.5 269.0 1.1 250.9 3.5 13.0 40.6 0.3 1.2 0.3 1.0 21.3 12.8 77.4 0.2 17.9 0.2 130.7 0.1 6.4 0.8 0.1 0.8 1.3 30.3 0.0 3.1 10.3 8.5 2.3 53.3 0.2 0.5 2.0 4.0 10.1 0.4 1.0 0.0 0.9 0.7 6.2 0.2 0.2 0.0 5.0 0.1 0.5 0.0 0.6 0.0 0.5 0.7 4.6 45.9 0.2 5.8 2.0 46.5 0.0 0.0 0.2 0.4 5.1 0.3 0.0 0.2 7.3 0.1 0.2 0.0 0.3 0.3 0.9 0.1 47.6 20.7 0.0 0.5 2.5 1.6 0.0 0.1 0.1 5.4 2.2 0.2 3.6 0.1 0.0 0.3 1.6 0.1 35.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.2 78.4 17.1 54.7 21.7 426.2 118.3 195.4 250.9 77.4 130.7 30.3 0.0 6.4 0.0 12.7 0.0 0.0 0.4 2.8 0.0 212.4 0.0 0.0 0.1 0.0 1.3 0.0 2.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.2 6.7 283.4 0.0 27.7 0.2 0.0 2.3 0.0 0.1 0.0 0.0 0.7 0.0 0.1 8.4 109.9 14.7 138.4 0.3 0.3 0.0 0.6 0.0 1.8 3.7 0.0 11.6 0.0 34.2 8.2 14.8 6.2 0.4 0.0 2.1 0.1 0.1 0.7 14.6 0.0 1.8 1.7 0.1 0.2 0.0 0.1 0.1 0.2 0.1 0.5 0.8 SCG3 "FLJ90833, SgIII" ENSG00000104112 "Secretogranin III" Q8WXD2 15 51681492-51721026 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 133.5;choroid plexus: 40.1;pituitary gland: 39.4;retina: 56.8" "Group enriched" "Detected in many" 4 "Astrocytes: 79.3;Bipolar cells: 120.4;Cone photoreceptor cells: 102.2;Enteroendocrine cells: 148.4;Excitatory neurons: 46.2;Horizontal cells: 148.0;Inhibitory neurons: 64.0;Ionocytes: 38.7;Oligodendrocyte precursor cells: 63.3;Rod photoreceptor cells: 93.3" "Group enriched" "Detected in many" 7 "glioma: 41.0;pancreatic cancer: 15.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "NTERA-2: 50.5;SCLC-21H: 121.2;SH-SY5Y: 57.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006880, CAB033274, HPA053715" Enhanced Supported Supported Vesicles "Secreted in brain" NA NA 3100000 "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" Vesicles "CAB033274: AB_2302033, HPA006880: AB_1079898, HPA053715: AB_2682239" "unprognostic (1.38e-2)" "unprognostic (2.42e-1)" "unprognostic (1.40e-1)" "unprognostic (5.24e-5)" "unprognostic (1.59e-2)" "unprognostic (3.63e-2)" "unprognostic (1.74e-1)" "unprognostic (9.93e-2)" "unprognostic (1.40e-1)" "unprognostic (2.46e-1)" "unprognostic (1.71e-2)" "unprognostic (8.17e-2)" "unprognostic (1.03e-1)" "unprognostic (2.78e-1)" "unprognostic (2.78e-1)" "unprognostic (8.88e-2)" "unprognostic (1.27e-1)" 0.5 16.7 71.0 1.1 87.0 0.6 0.5 85.8 133.5 0.1 40.1 1.8 2.3 0.2 0.3 0.3 0.3 0.2 0.2 88.2 112.7 0.2 0.2 0.6 0.4 68.7 75.8 0.1 15.6 0.2 39.4 0.1 68.9 0.3 2.0 56.8 0.2 0.0 0.1 0.6 2.0 0.5 71.9 0.2 9.9 2.6 79.8 0.5 1.0 0.0 0.2 0.2 0.2 71.6 0.2 0.1 4.8 0.3 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.2 0.2 0.3 0.5 0.0 0.6 0.4 0.1 0.0 0.1 0.1 0.5 0.1 0.3 0.1 0.0 0.3 3.0 0.1 0.1 0.1 0.0 0.2 0.0 0.2 0.2 0.8 0.0 0.3 0.1 0.1 50.5 0.1 0.2 0.3 0.1 0.4 0.0 0.5 121.2 57.5 0.2 0.4 0.2 15.5 0.1 3.8 0.1 0.3 0.7 0.2 0.2 0.4 0.2 0.4 0.7 0.3 11.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 71.0 87.0 85.8 133.5 88.2 112.7 68.7 75.8 68.9 71.9 79.8 71.6 0.2 0.0 0.0 79.3 0.0 0.3 0.0 0.3 0.0 120.4 0.0 0.1 0.2 0.0 0.1 0.0 102.2 0.0 0.0 0.2 1.9 0.4 20.0 0.0 0.0 4.3 148.4 0.0 46.2 1.0 0.1 4.1 0.0 0.0 0.0 0.0 1.8 0.0 0.4 148.0 64.0 3.4 38.7 0.0 0.3 11.3 0.0 0.1 1.8 7.5 6.7 19.2 0.0 63.3 8.9 5.3 0.0 0.4 0.0 0.4 0.1 0.0 0.8 93.3 0.0 0.4 0.2 13.8 5.8 0.0 0.0 0.0 0.0 0.2 0.3 0.3 SCGB2A1 "LPHC, MGB2, MGC71973, UGB3" ENSG00000124939 "Secretoglobin family 2A member 1" O75556 11 62208673-62213943 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "cervix: 2021.0;epididymis: 1372.0" "Group enriched" "Detected in many" 6 "Endometrial ciliated cells: 2506.4;Glandular and luminal cells: 2597.0" "Cancer enriched" "Detected in many" 5 "endometrial cancer: 971.9" "Region enhanced" "Detected in some" "medulla oblongata: 3.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "EFO-21: 8.6" HPA034584 Enhanced Approved Vesicles "Secreted in other tissues" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" Vesicles "HPA034584: AB_10602221" "unprognostic (7.73e-2)" "unprognostic (3.77e-1)" "prognostic favorable (1.22e-4)" "prognostic favorable (1.54e-8)" "unprognostic (2.98e-2)" "unprognostic (1.86e-2)" "unprognostic (3.39e-1)" "unprognostic (1.95e-1)" "unprognostic (2.69e-1)" "unprognostic (6.87e-3)" "prognostic favorable (6.36e-4)" "unprognostic (5.67e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-3)" "unprognostic (3.35e-1)" 0.2 0.0 0.0 0.2 0.0 0.0 57.8 0.0 0.0 2021.0 0.1 12.7 1.3 118.8 1372.0 4.2 238.4 13.4 0.2 0.1 0.4 1.9 0.1 2.4 0.0 3.5 1.4 0.7 17.2 1.1 5.1 0.1 0.8 6.8 16.3 0.0 29.6 15.6 0.0 8.6 1.0 2.2 0.5 0.0 45.9 0.0 1.1 2.7 5.8 0.0 0.1 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.3 0.0 0.1 0.0 0.7 0.1 0.0 1.6 0.4 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 3.5 1.4 0.8 0.5 1.1 0.2 0.6 0.0 4.8 0.0 0.4 0.1 3.8 4.8 0.0 0.0 123.6 71.0 0.0 48.6 10.1 16.5 0.0 0.2 1.6 9.7 3.9 6.6 0.0 2506.4 397.7 7.6 37.1 0.0 0.0 5.3 0.0 3.8 26.5 2597.0 0.0 0.3 0.0 0.1 4.9 0.0 0.0 59.9 10.2 0.3 0.0 0.0 0.0 14.1 5.4 0.0 0.0 0.0 0.0 0.0 0.0 15.3 10.8 0.0 0.0 27.0 0.7 0.1 109.3 0.0 0.0 0.0 8.5 0.0 0.0 1.7 0.4 0.0 13.7 0.1 7.0 16.6 SCN8A "CerIII, CIAT, MED, NaCh6, Nav1.6, PN4" ENSG00000196876 "Sodium voltage-gated channel alpha subunit 8" Q9UQD0 12 51590266-51812864 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 35.0" "Group enriched" "Detected in many" 8 "Excitatory neurons: 336.7;Inhibitory neurons: 280.1;Oligodendrocyte precursor cells: 104.5" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebral cortex: 35.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.7;ASC TERT1: 13.5;WM-115: 13.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022169, HPA043937, HPA073590" Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Vesicles, Cell Junctions" "CAB022169: , HPA043937: , HPA073590: " "unprognostic (2.96e-2)" "unprognostic (8.49e-2)" "unprognostic (6.93e-2)" "unprognostic (3.52e-6)" "unprognostic (8.13e-2)" "unprognostic (1.51e-2)" "unprognostic (1.16e-1)" "unprognostic (7.77e-2)" "unprognostic (5.44e-2)" "unprognostic (1.16e-1)" "unprognostic (4.73e-4)" "unprognostic (1.69e-2)" "unprognostic (1.29e-5)" "unprognostic (4.38e-1)" "unprognostic (1.56e-1)" "unprognostic (2.37e-1)" "unprognostic (4.75e-2)" 0.2 1.0 5.6 0.4 8.9 0.7 0.5 2.5 35.0 0.4 0.0 0.7 0.2 0.4 0.7 0.1 0.2 0.9 0.1 11.4 0.2 0.9 2.6 0.1 0.4 4.2 0.0 0.5 1.6 0.5 6.7 0.1 3.8 0.6 0.9 7.9 0.6 0.2 0.3 0.3 0.2 0.1 0.0 0.6 1.0 1.7 2.4 0.5 0.5 0.1 0.2 0.2 0.2 11.5 1.7 1.3 13.7 0.2 1.8 13.5 0.3 8.0 12.5 9.1 8.5 2.8 1.6 0.4 1.9 9.9 4.4 0.1 2.3 0.0 10.5 1.6 0.8 0.1 0.3 0.3 0.1 0.2 1.1 1.8 0.0 6.5 1.4 3.4 9.8 3.5 0.2 0.2 5.5 1.0 2.5 0.2 4.9 0.9 4.8 0.1 0.7 0.0 0.0 0.5 5.6 2.2 4.5 2.1 0.3 2.1 0.4 0.2 2.8 8.9 6.3 3.3 5.2 0.2 0.1 0.0 1.8 1.9 13.0 0.5 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.4 0.1 0.0 0.1 0.0 0.0 5.6 8.9 2.5 35.0 11.4 0.2 4.2 0.0 3.8 0.0 2.4 11.5 1.2 0.0 0.0 27.1 0.0 0.0 0.5 0.0 3.4 16.7 2.6 1.8 1.4 1.5 0.0 0.0 10.4 0.0 0.3 1.0 0.0 0.5 0.6 0.0 0.7 1.3 11.4 0.0 336.7 0.5 0.0 0.1 3.1 0.0 0.0 0.7 1.1 4.3 0.0 5.0 280.1 1.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 20.6 0.0 4.7 0.0 104.5 14.2 0.7 0.5 0.7 0.0 0.4 0.0 0.7 0.0 11.2 0.0 0.4 0.3 3.8 10.2 0.1 0.0 0.0 0.3 0.0 0.9 0.3 SCRN3 FLJ23142 ENSG00000144306 "Secernin 3" Q0VDG4 2 174395730-174429575 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034689, HPA034690" Approved Approved Vesicles,Cytosol NA NA 27000 "Cluster 1: Neutrophils - Mixed function" "Cluster 8: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Cytosol" "HPA034689: AB_2674282, HPA034690: AB_10670574" "unprognostic (5.39e-3)" "unprognostic (4.58e-2)" "unprognostic (2.06e-2)" "unprognostic (3.58e-1)" "unprognostic (1.91e-1)" "unprognostic (1.89e-1)" "unprognostic (9.89e-2)" "unprognostic (1.57e-1)" "unprognostic (5.14e-2)" "unprognostic (5.85e-2)" "unprognostic (8.81e-2)" "unprognostic (1.30e-1)" "unprognostic (6.62e-3)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (5.57e-2)" "unprognostic (1.57e-1)" 16.4 16.4 11.8 9.9 14.4 5.2 13.5 14.7 16.0 9.5 7.0 12.9 18.5 11.9 11.4 16.2 10.4 11.2 26.0 10.8 13.6 20.2 22.0 12.2 11.4 14.6 13.4 13.2 14.7 27.7 14.0 13.1 13.6 15.2 13.2 22.8 11.0 12.5 40.5 13.8 14.3 14.0 12.9 11.8 12.4 10.6 14.1 12.4 20.3 35.8 12.1 10.4 8.3 18.5 15.9 9.7 25.8 22.8 18.8 21.1 13.7 24.1 19.0 18.2 22.0 9.6 11.4 3.0 15.6 24.2 14.0 15.5 19.3 21.1 23.9 34.8 17.8 29.7 21.1 7.5 27.8 22.8 15.0 23.5 25.4 34.4 24.5 20.4 21.8 16.7 20.2 11.1 25.0 18.0 18.9 22.2 12.0 35.4 41.0 9.3 25.7 17.5 21.2 16.5 16.0 44.5 16.6 16.2 30.7 26.4 21.8 21.7 15.7 20.9 10.9 25.6 21.0 29.4 32.8 0.5 22.9 11.2 21.8 7.2 5.2 2.2 4.8 3.3 3.4 8.6 5.1 4.6 5.1 11.0 7.8 6.3 20.0 6.9 4.3 8.0 5.6 2.6 11.8 14.4 14.7 16.0 10.8 13.6 14.6 13.4 13.6 12.9 14.1 18.5 7.8 9.6 15.6 18.6 7.0 3.6 12.1 23.7 12.5 12.8 7.9 6.3 22.8 4.3 12.5 9.2 10.4 10.7 3.8 8.4 13.7 9.1 5.1 9.4 8.3 6.0 6.0 11.6 21.0 9.8 6.3 6.9 11.2 5.4 8.8 9.5 8.6 8.7 9.3 18.5 26.3 7.3 20.3 5.8 2.2 4.0 4.7 6.2 3.6 6.5 6.1 22.6 7.2 27.6 25.7 12.2 4.0 6.8 10.3 5.4 9.9 12.5 13.6 15.0 0.0 8.2 7.1 18.9 7.1 20.4 4.8 6.8 5.8 13.0 6.4 9.7 SDF2 ENSG00000132581 "Stromal cell derived factor 2" Q99470 17 28648346-28662189 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 211.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042799 Approved Vesicles "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA042799: AB_10794533" "unprognostic (3.91e-1)" "unprognostic (2.79e-1)" "unprognostic (2.03e-1)" "unprognostic (5.77e-3)" "unprognostic (3.90e-2)" "unprognostic (1.88e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (2.28e-3)" "unprognostic (3.20e-3)" "unprognostic (3.02e-1)" "unprognostic (1.04e-2)" "unprognostic (1.52e-1)" "unprognostic (1.79e-1)" "unprognostic (1.39e-3)" "unprognostic (2.21e-1)" "unprognostic (7.75e-3)" "unprognostic (6.61e-2)" 16.2 32.2 14.6 8.7 14.6 8.8 14.2 14.9 15.2 17.5 18.5 15.7 8.0 14.4 27.2 13.8 17.3 13.0 17.5 14.9 16.3 18.5 23.2 15.4 9.4 15.4 15.3 19.7 19.9 20.1 19.1 20.5 16.0 18.2 11.1 6.6 21.8 15.7 14.7 11.5 13.0 14.4 15.3 16.1 15.3 9.4 15.9 12.7 16.2 12.9 8.1 20.2 14.3 14.9 18.8 54.3 25.2 18.7 107.1 29.6 18.0 53.6 48.4 39.6 49.8 34.6 23.5 8.0 47.8 57.6 36.6 30.5 24.7 22.6 27.8 62.3 29.8 13.7 26.6 28.6 30.9 8.1 17.2 53.7 28.5 38.3 8.8 34.4 39.9 11.0 14.9 19.4 45.1 35.9 20.7 22.2 12.9 48.8 19.2 12.5 37.1 24.8 45.3 29.6 15.6 18.1 42.3 32.4 30.3 37.5 43.7 10.4 45.0 21.0 23.3 24.2 31.2 25.2 35.2 11.9 32.0 12.9 23.9 189.1 45.1 129.1 64.4 39.6 62.6 50.8 52.2 62.8 30.0 44.4 47.1 55.9 203.1 71.1 42.1 62.5 74.2 59.7 14.6 14.6 14.9 15.2 14.9 16.3 15.4 15.3 16.0 15.3 15.9 14.9 61.1 25.6 21.7 10.4 45.5 34.0 59.1 125.6 41.5 26.4 49.4 44.6 13.1 38.6 71.1 42.3 25.0 130.3 74.0 82.8 29.4 74.8 7.4 36.2 43.6 52.2 57.1 37.5 11.1 47.2 109.0 52.6 27.5 44.9 21.0 47.2 53.2 46.2 56.7 13.5 12.2 57.5 71.2 44.9 49.7 3.9 76.1 38.1 37.4 8.4 50.2 49.9 56.7 11.1 17.8 80.4 90.4 66.5 46.2 54.1 88.0 50.7 47.8 31.1 72.3 36.7 48.1 30.5 32.1 40.6 37.6 211.0 53.2 86.0 46.2 86.9 SEC13 "D3S1231E, npp-20, SEC13L1, SEC13R" ENSG00000157020 "SEC13 homolog, nuclear pore and COPII coat complex component" P55735 3 10293131-10321112 "Metabolic proteins, Predicted intracellular proteins, Transporters" "ER-Golgi transport, mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035292, HPA057943" Approved Supported Nucleoplasm,Vesicles NA NA 35000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 28: BEWO - Transcription regulation" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Vesicles" "HPA035292: AB_10959451, HPA057943: AB_2683560" "unprognostic (3.33e-3)" "unprognostic (6.16e-2)" "unprognostic (2.28e-2)" "unprognostic (4.95e-2)" "unprognostic (4.22e-1)" "unprognostic (2.64e-2)" "prognostic unfavorable (1.73e-4)" "unprognostic (2.43e-1)" "unprognostic (2.67e-1)" "unprognostic (1.69e-1)" "unprognostic (4.58e-1)" "unprognostic (1.17e-1)" "unprognostic (1.40e-1)" "unprognostic (4.60e-1)" "unprognostic (2.43e-1)" "unprognostic (2.03e-1)" "unprognostic (8.33e-2)" 62.1 71.5 51.0 61.8 55.6 58.4 58.9 55.9 57.6 83.7 59.2 68.8 114.7 66.4 59.4 72.6 57.4 47.5 71.1 52.2 57.2 67.4 92.1 64.3 54.6 54.6 54.6 52.6 85.2 64.6 109.2 68.5 55.2 53.8 65.7 21.2 96.2 64.9 111.5 62.7 96.6 76.6 54.3 59.4 67.3 39.4 54.2 70.3 57.6 87.3 65.4 69.9 59.2 58.2 122.6 182.1 142.9 55.2 228.0 251.6 474.4 243.8 296.1 279.3 319.8 150.3 97.6 110.7 109.6 390.1 156.8 49.0 186.4 218.3 142.4 97.8 194.5 136.2 137.3 363.7 311.8 156.7 115.5 224.7 173.1 292.6 181.5 205.6 337.0 146.2 148.4 159.8 219.5 250.2 153.8 169.9 160.9 158.0 218.7 148.1 102.4 198.2 172.4 90.2 80.3 99.4 107.3 98.7 101.3 119.3 127.5 150.8 253.6 114.2 130.2 172.6 213.3 131.7 198.4 258.6 215.5 217.5 193.0 127.3 163.2 106.6 84.4 144.9 94.6 96.5 83.6 82.1 222.5 82.6 68.0 71.2 105.8 93.9 116.4 198.3 106.1 176.5 51.0 55.6 55.9 57.6 52.2 57.2 54.6 54.6 55.2 54.3 54.2 58.2 23.9 48.1 61.9 14.0 45.8 39.4 50.4 73.6 31.3 16.2 29.5 26.4 40.2 30.0 68.3 27.6 10.4 119.9 36.5 60.1 66.5 79.3 25.6 31.8 44.0 51.0 41.4 33.0 17.3 109.2 166.6 74.1 73.9 47.1 43.1 35.5 33.9 57.3 104.9 11.8 13.7 108.2 50.8 33.0 46.7 10.2 53.4 45.0 26.6 12.2 64.2 37.4 35.0 11.6 12.6 81.8 56.1 52.6 203.2 52.4 187.5 112.0 64.5 21.1 13.1 37.7 63.6 54.9 38.9 43.7 40.2 168.6 36.5 35.8 74.2 62.3 SEC23A ENSG00000100934 "Sec23 homolog A, COPII coat complex component" Q15436 14 39031919-39109646 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 347.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043806, HPA069974" Uncertain Approved Nucleoplasm,Vesicles NA NA 83000 "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles" "HPA043806: , HPA069974: AB_2686223" "unprognostic (2.40e-1)" "prognostic unfavorable (5.75e-4)" "prognostic favorable (3.56e-4)" "unprognostic (3.30e-2)" "unprognostic (1.18e-1)" "unprognostic (6.39e-2)" "unprognostic (1.15e-2)" "unprognostic (5.85e-2)" "unprognostic (1.71e-1)" "unprognostic (2.69e-1)" "unprognostic (1.28e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (1.69e-4)" "prognostic unfavorable (2.94e-4)" "unprognostic (1.16e-1)" "unprognostic (2.73e-1)" "unprognostic (1.41e-3)" 45.9 32.0 11.4 31.8 14.2 13.1 20.9 18.3 16.8 36.2 31.4 40.0 57.7 42.7 19.9 34.1 21.5 32.1 46.9 13.3 18.9 23.1 80.8 20.2 21.0 13.8 14.0 33.9 12.0 8.1 10.5 27.1 15.3 34.0 34.2 38.5 10.5 52.6 54.2 12.8 52.6 90.5 7.6 20.5 16.8 23.5 12.7 18.9 17.9 58.5 22.0 40.7 17.9 15.4 52.1 90.8 76.9 74.7 161.3 173.0 25.9 195.1 176.4 135.2 166.8 93.2 44.2 12.6 46.9 279.6 54.9 41.2 99.6 86.3 208.6 39.6 36.9 21.8 67.7 347.3 122.4 35.9 31.3 134.0 48.8 91.6 73.7 114.6 130.8 26.9 15.6 30.1 125.8 47.5 32.9 16.9 18.4 81.7 91.3 44.0 111.8 19.1 84.7 75.6 8.5 20.5 132.8 43.0 51.8 68.6 51.5 12.4 138.4 75.0 57.8 110.8 52.0 27.0 36.6 56.0 50.3 31.4 70.2 70.5 34.3 38.6 26.6 29.3 38.4 23.6 33.1 34.9 31.1 21.1 34.9 28.0 29.5 42.1 27.3 26.7 38.1 31.4 11.4 14.2 18.3 16.8 13.3 18.9 13.8 14.0 15.3 7.6 12.7 15.4 35.4 16.0 26.9 34.9 30.5 25.9 33.5 15.5 15.4 39.7 11.8 10.3 54.6 15.7 18.8 31.3 68.8 16.0 36.0 87.0 7.9 9.8 13.4 11.3 42.8 41.1 24.5 6.1 48.3 5.6 43.7 55.0 26.5 18.8 27.9 56.9 118.9 133.6 25.6 30.3 51.1 31.6 12.2 36.4 32.3 18.6 74.9 24.3 24.9 48.7 25.6 19.4 32.0 34.2 44.3 17.8 34.1 71.5 38.5 37.5 88.6 32.8 10.1 58.7 39.5 27.6 51.4 18.0 15.5 15.7 24.0 24.8 32.3 31.0 30.2 56.5 SEC23B "CDA-II, CDAII, CDAN2, HEMPAS" ENSG00000101310 "SEC23 homolog B, COPII coat complex component" Q15437 20 18507520-18561415 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008216, HPA069974" Uncertain Supported Vesicles NA Yes 16000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA008216: AB_1079895, HPA069974: AB_2686223" "unprognostic (4.47e-2)" "unprognostic (2.67e-2)" "unprognostic (3.52e-1)" "prognostic favorable (8.25e-4)" "unprognostic (1.24e-1)" "unprognostic (1.33e-1)" "unprognostic (5.44e-3)" "unprognostic (6.01e-2)" "unprognostic (1.39e-1)" "unprognostic (8.75e-2)" "unprognostic (1.97e-1)" "unprognostic (9.97e-2)" "unprognostic (3.91e-2)" "unprognostic (1.72e-2)" "unprognostic (4.26e-2)" "unprognostic (2.81e-2)" "unprognostic (8.21e-2)" 19.6 38.3 18.7 32.0 27.1 36.0 37.8 24.7 25.9 36.2 27.4 31.6 23.8 17.2 53.8 28.4 29.5 23.1 8.5 19.5 22.4 37.4 30.6 29.7 30.5 27.2 23.8 16.9 57.1 50.6 32.6 24.2 27.2 34.8 32.7 40.7 70.9 35.9 4.1 18.2 23.3 18.5 24.5 25.5 38.2 34.8 23.2 27.6 59.5 6.2 38.0 30.5 12.6 38.9 85.0 93.9 49.8 48.7 32.3 36.6 116.0 69.8 45.3 80.0 68.7 84.9 73.8 37.5 44.9 50.4 107.0 88.5 88.5 120.7 86.2 47.5 43.1 64.9 35.6 130.6 70.5 90.2 78.7 28.0 71.8 118.0 151.4 47.6 50.6 34.0 74.8 82.4 55.1 90.7 59.8 49.5 48.0 118.9 101.6 62.4 77.7 122.1 83.0 85.6 78.8 58.0 83.6 188.9 80.6 62.6 82.3 94.4 45.3 53.1 29.8 58.4 87.1 104.2 155.9 60.1 45.3 47.8 74.4 147.9 94.1 106.0 57.2 95.6 78.7 67.2 56.8 61.4 107.9 61.2 51.3 54.0 48.0 78.8 94.9 80.7 75.4 103.7 18.7 27.1 24.7 25.9 19.5 22.4 27.2 23.8 27.2 24.5 23.2 38.9 8.5 16.0 43.5 15.3 24.7 11.5 21.0 34.3 10.2 21.0 21.5 15.6 3.0 20.0 42.5 31.3 16.7 34.3 36.0 26.2 58.7 36.1 95.6 25.4 12.4 11.3 19.7 7.4 17.9 33.4 30.0 11.7 25.0 31.3 15.9 13.6 11.0 25.6 42.9 13.5 20.5 34.7 26.4 38.7 21.0 11.3 14.3 30.3 23.2 15.0 33.1 23.9 9.2 23.1 27.0 31.8 24.2 10.5 59.0 30.1 11.8 53.2 45.4 20.4 19.7 12.4 12.2 48.7 22.1 15.8 14.2 65.8 21.0 16.0 21.5 28.3 SEC23IP p125 ENSG00000107651 "SEC23 interacting protein" Q9Y6Y8 10 119892730-119944657 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038403, HPA043305" Approved Enhanced Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Vesicles "HPA038403: AB_10675796, HPA043305: AB_2678416" "unprognostic (4.05e-2)" "unprognostic (5.01e-2)" "unprognostic (8.70e-2)" "unprognostic (1.35e-1)" "unprognostic (3.12e-1)" "unprognostic (1.07e-1)" "unprognostic (9.52e-3)" "unprognostic (1.78e-1)" "unprognostic (3.36e-1)" "unprognostic (2.33e-1)" "unprognostic (1.45e-2)" "unprognostic (3.00e-2)" "unprognostic (1.11e-2)" "unprognostic (2.08e-1)" "unprognostic (2.23e-1)" "unprognostic (6.81e-3)" "unprognostic (3.43e-2)" 10.3 9.7 3.5 12.0 3.9 14.1 11.8 6.2 4.6 11.2 6.4 12.6 10.4 11.9 12.1 9.4 8.8 9.6 7.7 4.0 4.0 10.3 12.6 10.2 13.7 4.2 4.3 10.0 11.1 9.8 8.5 12.4 4.0 13.1 13.0 9.0 10.3 9.9 9.8 10.4 9.5 16.4 3.1 11.7 17.5 11.5 4.6 11.1 12.5 8.4 13.4 12.0 8.3 6.3 32.4 30.2 24.3 31.9 22.4 25.3 19.0 27.2 39.5 26.1 31.6 31.0 22.9 30.2 14.7 36.2 32.5 23.9 27.9 29.2 39.5 27.2 28.7 25.1 16.3 34.0 31.0 29.6 29.9 31.4 18.4 30.8 30.5 28.3 36.3 15.5 19.1 21.4 28.7 19.2 25.9 28.2 29.5 28.6 20.9 23.7 44.7 17.3 26.1 25.6 9.6 25.5 25.0 19.9 24.1 24.9 17.5 21.7 29.6 15.8 18.5 23.8 35.1 33.5 32.6 38.7 27.6 37.4 14.1 14.3 10.5 10.3 10.7 16.3 13.9 11.3 10.5 12.4 11.9 9.1 11.1 10.7 3.8 13.0 18.1 7.2 11.9 9.6 3.5 3.9 6.2 4.6 4.0 4.0 4.2 4.3 4.0 3.1 4.6 6.3 15.1 12.8 28.3 21.9 20.9 8.4 19.3 18.1 13.1 17.3 19.1 12.1 17.4 27.1 24.5 18.4 6.2 17.8 18.7 19.7 5.9 16.8 26.1 15.1 22.1 19.9 19.9 21.2 28.3 14.4 18.9 21.4 44.9 15.5 22.1 21.0 14.3 25.5 23.3 11.8 30.2 24.3 26.4 24.6 12.2 24.9 14.0 23.3 8.8 39.4 21.3 14.6 16.5 31.7 37.5 20.2 19.8 15.1 23.7 23.4 16.0 19.2 25.4 23.7 0.0 16.8 17.9 25.0 19.8 19.1 13.9 23.1 18.2 24.2 20.8 21.1 SEC24A ENSG00000113615 "SEC24 homolog A, COPII coat complex component" O95486 5 134648785-134727909 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 89.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038901, HPA056825" Approved Approved "Nucleoli fibrillar center,Vesicles" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" "Nucleoli fibrillar center, Vesicles" "HPA038901: AB_10674843, HPA056825: AB_2683249" "unprognostic (9.10e-3)" "prognostic unfavorable (3.70e-4)" "unprognostic (2.76e-2)" "unprognostic (4.98e-2)" "unprognostic (2.08e-1)" "unprognostic (4.53e-2)" "unprognostic (1.17e-1)" "unprognostic (6.66e-2)" "unprognostic (2.41e-1)" "unprognostic (5.40e-2)" "unprognostic (1.03e-2)" "unprognostic (3.54e-1)" "unprognostic (1.18e-3)" "unprognostic (4.77e-2)" "unprognostic (3.00e-2)" "unprognostic (9.37e-3)" "unprognostic (8.97e-2)" 9.7 13.3 2.2 13.3 2.2 17.6 10.0 3.6 3.9 11.7 13.6 11.7 21.3 8.7 8.1 10.5 5.4 10.5 6.3 2.6 3.4 9.0 34.6 7.6 10.7 2.4 3.7 6.5 15.6 11.8 7.9 15.5 2.2 10.0 13.0 6.9 16.9 8.1 11.9 5.8 22.0 10.7 1.8 9.6 14.6 6.0 2.7 9.0 11.5 7.3 14.2 13.4 7.2 2.7 21.6 12.1 22.3 17.1 32.4 32.6 24.1 32.6 40.2 25.7 44.1 45.0 12.9 16.1 21.6 38.1 27.3 12.0 28.2 25.3 44.4 19.8 13.3 13.7 18.6 33.5 23.0 16.3 26.4 20.5 14.1 24.8 18.1 22.4 23.7 11.2 18.9 24.3 25.9 11.7 15.6 11.9 14.6 19.7 7.6 15.7 19.8 18.9 16.8 16.9 9.4 9.7 21.2 10.1 26.8 38.6 17.8 13.4 26.0 21.2 8.0 27.0 19.8 42.7 40.6 26.5 24.9 17.0 41.2 3.3 2.1 1.5 1.6 2.3 2.7 2.1 1.7 1.6 2.5 1.3 1.6 1.9 1.2 2.0 2.5 1.6 1.7 1.2 2.2 2.2 3.6 3.9 2.6 3.4 2.4 3.7 2.2 1.8 2.7 2.7 14.4 6.4 8.4 15.3 15.2 31.9 14.0 10.7 8.0 7.8 20.6 9.1 6.3 11.5 18.6 3.7 12.5 10.3 14.6 22.1 5.9 6.3 12.0 25.6 33.4 12.2 9.5 6.7 29.6 13.6 17.2 18.1 32.6 70.1 12.7 8.3 15.7 54.8 11.5 13.5 25.7 19.9 8.2 16.2 32.0 5.7 8.4 20.7 14.2 15.0 9.8 6.6 6.2 35.2 23.2 15.0 11.5 13.5 89.1 22.0 42.6 12.3 13.8 7.7 6.6 19.6 12.8 15.2 8.2 17.0 32.4 22.7 13.1 8.0 15.2 36.0 SEC24B ENSG00000138802 "SEC24 homolog B, COPII coat complex component" O95487 4 109433772-109540896 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 88.1;Oligodendrocytes: 91.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038181 Approved Approved Nucleoplasm,Vesicles NA NA 14000 "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Vesicles" "HPA038181: AB_10672472" "unprognostic (1.19e-1)" "unprognostic (4.31e-3)" "unprognostic (8.58e-3)" "unprognostic (9.95e-2)" "unprognostic (1.22e-1)" "unprognostic (1.46e-1)" "unprognostic (6.67e-2)" "unprognostic (3.18e-2)" "unprognostic (1.06e-1)" "unprognostic (1.85e-3)" "unprognostic (2.51e-3)" "unprognostic (7.47e-2)" "prognostic favorable (2.33e-6)" "unprognostic (2.67e-1)" "unprognostic (2.40e-1)" "unprognostic (6.02e-2)" "unprognostic (1.73e-1)" 19.3 13.7 7.2 13.2 7.5 28.0 17.4 14.7 9.9 16.3 15.0 15.7 14.1 16.9 12.9 17.2 15.0 13.8 15.6 6.8 7.6 16.7 46.2 14.8 13.9 7.5 6.9 21.4 18.6 21.9 11.2 20.6 7.8 15.6 16.1 32.6 14.3 16.1 28.1 19.8 12.7 17.9 7.3 14.7 13.3 11.3 7.4 27.2 18.5 22.9 16.7 17.5 16.0 9.6 21.1 18.9 29.3 22.1 34.9 34.7 16.8 27.0 32.8 22.5 19.8 17.4 23.8 19.4 13.8 41.1 19.3 17.4 33.2 26.9 33.0 24.0 16.6 20.3 16.6 19.2 23.4 27.0 22.9 34.4 33.7 25.8 30.8 31.8 33.7 19.7 31.5 17.3 33.6 17.1 39.2 12.5 11.2 26.1 15.0 25.1 25.9 11.3 27.1 25.8 20.6 16.5 20.8 43.8 16.0 30.0 12.9 10.3 31.3 26.2 17.6 23.1 19.5 16.6 22.3 18.1 23.3 10.7 21.5 6.1 9.5 11.5 8.6 10.4 9.5 10.3 9.5 9.0 11.8 8.9 10.8 9.3 9.2 11.5 10.5 4.6 9.1 9.0 7.2 7.5 14.7 9.9 6.8 7.6 7.5 6.9 7.8 7.3 7.4 9.6 25.1 25.6 15.4 63.0 23.0 35.4 20.1 11.8 28.5 27.0 12.9 10.8 30.5 14.3 17.4 5.5 6.2 13.3 13.2 22.7 5.9 10.4 4.4 18.7 14.6 22.5 15.6 11.6 71.1 13.1 9.2 16.4 19.9 21.9 11.4 15.9 16.8 29.9 12.3 16.8 84.1 15.6 4.1 17.6 16.8 7.9 20.5 18.7 17.8 88.1 14.5 20.3 13.4 76.9 91.6 12.6 18.7 21.8 21.3 22.5 16.5 9.6 19.6 22.0 13.1 16.3 16.8 14.7 13.6 22.2 36.7 16.1 17.0 9.9 14.4 30.3 SEC24C KIAA0079 ENSG00000176986 "SEC24 homolog C, COPII coat complex component" P53992 10 73744372-73772161 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA040196, HPA040213" Supported Supported Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA040196: AB_10796449, HPA040213: AB_10796451" "unprognostic (5.06e-2)" "unprognostic (1.00e-2)" "unprognostic (2.17e-1)" "unprognostic (3.54e-1)" "unprognostic (8.46e-2)" "unprognostic (7.23e-2)" "unprognostic (9.06e-2)" "unprognostic (4.55e-2)" "unprognostic (1.64e-1)" "unprognostic (2.46e-2)" "unprognostic (1.02e-1)" "unprognostic (1.35e-1)" "unprognostic (7.71e-2)" "unprognostic (8.34e-3)" "unprognostic (2.11e-1)" "unprognostic (3.35e-2)" "unprognostic (1.77e-2)" 27.8 42.9 20.1 31.6 21.2 16.2 27.4 23.1 26.8 42.5 20.7 34.2 27.4 36.4 33.2 69.0 30.7 24.0 34.5 20.4 21.2 29.8 45.8 30.5 31.4 21.4 20.1 33.2 34.9 50.5 45.4 36.4 20.9 37.7 27.6 29.1 36.9 31.1 49.7 35.8 31.7 32.1 18.3 37.1 34.1 27.7 22.7 35.2 34.0 33.9 43.3 35.5 38.8 23.0 72.7 71.8 55.6 99.9 59.2 48.3 45.6 53.6 90.4 70.4 65.7 67.2 47.9 57.3 43.3 72.0 48.1 61.4 78.3 70.7 60.4 76.6 55.6 53.1 50.5 71.2 47.0 80.7 71.1 41.5 76.8 61.8 76.4 89.2 73.6 44.6 64.1 80.8 69.9 64.7 60.4 55.3 34.8 68.3 259.2 65.2 45.0 47.0 46.5 40.8 20.0 51.7 41.9 144.6 60.1 51.7 106.3 70.6 72.7 29.5 53.1 57.7 62.5 82.0 85.9 84.0 84.0 80.8 35.0 28.2 15.8 13.6 27.4 21.4 35.5 12.6 16.2 21.6 18.1 9.4 11.7 15.8 11.5 22.4 19.1 14.8 10.9 22.7 20.1 21.2 23.1 26.8 20.4 21.2 21.4 20.1 20.9 18.3 22.7 23.0 12.1 35.3 28.6 16.3 11.6 8.7 4.7 11.5 6.2 15.1 17.0 14.9 2.3 14.3 17.6 14.7 16.7 17.8 18.6 24.7 3.9 15.1 8.8 10.9 13.0 11.0 19.2 5.9 14.6 19.4 16.4 9.7 19.9 17.0 22.2 20.1 16.4 19.9 17.1 15.2 15.7 18.4 8.2 11.7 8.4 6.0 11.8 12.4 5.4 6.5 12.3 10.3 17.5 14.1 16.8 23.8 14.4 11.7 21.9 10.8 20.0 10.4 8.2 14.7 6.6 10.0 9.7 10.3 8.3 11.5 11.4 25.2 16.9 14.7 16.1 10.9 SEC24D KIAA0755 ENSG00000150961 "SEC24 homolog D, COPII coat complex component" O94855 4 118722823-118838683 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Craniosynostosis, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 118.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041626, HPA053486" Approved Approved Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA041626: AB_10796348, HPA053486: AB_2682166" "unprognostic (9.06e-2)" "unprognostic (3.11e-1)" "unprognostic (3.23e-2)" "unprognostic (8.60e-3)" "unprognostic (1.05e-1)" "unprognostic (1.92e-1)" "unprognostic (1.93e-1)" "unprognostic (2.58e-1)" "unprognostic (9.39e-2)" "unprognostic (3.23e-1)" "unprognostic (1.22e-1)" "unprognostic (6.85e-2)" "prognostic unfavorable (3.42e-6)" "unprognostic (1.09e-3)" "unprognostic (5.64e-2)" "unprognostic (4.30e-3)" "unprognostic (1.37e-1)" 21.1 13.3 2.7 27.2 3.3 17.6 19.4 1.1 4.4 49.0 4.5 24.4 37.5 26.4 36.9 12.4 20.7 31.9 20.1 5.5 4.6 9.5 52.0 22.9 18.4 1.3 2.3 15.3 35.8 10.2 23.3 36.8 1.6 22.0 32.3 1.6 22.9 26.4 5.8 9.9 40.8 41.3 0.6 18.0 29.6 18.4 2.8 14.6 35.6 6.1 21.9 28.9 16.7 2.6 29.6 15.4 35.3 28.6 98.0 130.2 24.8 124.5 136.8 62.1 73.5 16.9 21.3 23.2 17.3 198.7 32.1 10.0 19.4 39.2 66.8 19.4 10.5 25.7 22.8 70.6 99.8 68.6 46.0 77.9 21.6 54.9 89.2 110.3 103.9 15.8 6.7 69.1 98.5 20.6 33.2 20.4 33.3 66.5 24.8 20.1 25.8 41.2 55.6 14.7 20.9 41.8 17.8 89.1 15.3 50.9 12.6 53.9 113.9 48.0 15.3 69.7 28.6 53.1 21.1 38.6 104.5 42.8 68.5 5.8 5.6 16.3 3.1 6.0 6.3 1.7 3.2 4.4 5.8 1.5 2.1 2.7 4.8 5.0 7.4 2.9 4.7 2.6 2.7 3.3 1.1 4.4 5.5 4.6 1.3 2.3 1.6 0.6 2.8 2.6 13.0 3.2 15.3 4.9 19.4 21.0 15.2 19.4 25.6 4.5 19.0 10.2 5.9 17.2 25.5 14.7 0.0 24.3 24.2 18.2 0.0 10.3 101.3 17.4 61.3 23.2 41.3 6.1 57.4 25.3 54.2 49.7 37.2 39.4 8.2 14.2 21.8 70.0 28.1 1.7 6.5 81.0 12.2 34.0 54.4 84.6 45.7 25.1 17.8 48.7 18.3 1.3 13.4 37.7 3.7 13.0 13.6 38.4 118.8 30.7 48.1 4.2 23.0 2.9 26.3 17.5 38.7 14.5 9.7 10.4 17.6 45.0 16.3 34.2 19.1 40.1 SEC31A "ABP125, ABP130, KIAA0905, SEC31L1" ENSG00000138674 "SEC31 homolog A, COPII coat complex component" O94979 4 82818509-82901166 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005457 Approved Supported Vesicles,Cytosol NA NA 40000 "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Cytosol" "HPA005457: AB_1079896" "unprognostic (3.50e-2)" "unprognostic (2.28e-3)" "unprognostic (2.55e-2)" "unprognostic (1.58e-2)" "unprognostic (2.93e-1)" "unprognostic (6.52e-2)" "prognostic unfavorable (3.32e-4)" "unprognostic (6.14e-3)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "unprognostic (4.21e-3)" "unprognostic (3.62e-1)" "unprognostic (1.64e-1)" "unprognostic (5.53e-3)" "unprognostic (2.92e-1)" "unprognostic (2.85e-1)" "prognostic unfavorable (2.69e-4)" 98.7 103.3 52.2 78.4 54.3 119.4 111.4 62.4 70.1 145.5 94.9 107.1 124.2 119.7 162.1 92.6 90.9 122.1 110.7 54.0 61.4 133.6 174.8 96.2 88.2 58.4 58.7 152.8 192.6 116.4 108.4 143.2 58.7 113.4 127.2 87.9 134.0 111.3 96.8 107.8 111.0 131.5 50.9 76.5 110.1 77.8 54.4 93.8 168.0 85.6 102.1 113.1 94.1 63.9 146.2 65.2 183.6 130.4 318.9 394.5 133.3 264.8 295.4 146.0 179.2 113.2 182.3 188.3 113.7 532.2 84.6 68.1 183.3 176.2 200.4 193.4 72.7 115.3 110.5 302.1 316.4 124.4 140.7 380.5 217.7 223.5 254.3 251.2 240.5 83.8 178.4 181.1 264.2 128.6 164.9 99.6 126.1 154.0 58.3 121.2 100.1 140.3 237.2 83.0 118.6 131.2 105.7 180.7 174.9 184.8 142.1 137.8 248.2 190.7 98.9 169.0 168.8 135.1 62.4 256.7 190.6 147.8 224.2 84.3 66.9 51.2 65.1 74.0 80.5 60.0 57.6 64.3 73.3 50.0 56.9 54.6 19.2 89.9 83.1 61.1 52.7 71.8 52.2 54.3 62.4 70.1 54.0 61.4 58.4 58.7 58.7 50.9 54.4 63.9 62.6 105.8 85.3 50.9 58.1 60.5 60.5 64.1 56.9 52.3 54.5 43.7 85.5 51.5 109.8 47.8 54.2 57.3 61.0 62.8 27.4 65.8 30.6 90.1 164.6 65.0 38.3 41.2 61.0 71.2 85.3 125.2 100.9 119.7 75.2 241.0 65.0 94.0 45.9 42.1 60.0 99.4 50.8 51.2 55.3 19.3 139.1 63.8 51.6 67.5 60.4 36.5 38.1 74.9 72.6 67.5 46.3 126.0 152.2 76.3 121.0 65.9 100.5 66.9 52.6 86.5 98.9 30.3 34.6 62.2 74.2 81.5 55.4 78.9 54.9 101.1 SEC31B "DKFZP434M183, SEC31B-1, SEC31L2" ENSG00000075826 "SEC31 homolog B, COPII coat complex component" Q9NQW1 10 100486646-100519864 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 28.7;Bipolar cells: 32.2;Cone photoreceptor cells: 39.6;Excitatory neurons: 38.1;Horizontal cells: 40.4;Inhibitory neurons: 40.7;Oligodendrocyte precursor cells: 32.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 9.1;JURKAT: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA035882, HPA040819, HPA060052" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 59: Non-specific - Translation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Vesicles, Cytosol" "HPA035882: AB_10795246, HPA040819: AB_10794151, HPA060052: " "unprognostic (1.23e-1)" "unprognostic (3.13e-3)" "unprognostic (3.39e-3)" "unprognostic (1.03e-2)" "unprognostic (4.85e-2)" "unprognostic (1.42e-3)" "unprognostic (1.97e-3)" "unprognostic (6.63e-2)" "unprognostic (2.22e-1)" "unprognostic (2.25e-2)" "unprognostic (1.10e-4)" "unprognostic (8.23e-3)" "prognostic unfavorable (6.41e-7)" "unprognostic (2.31e-2)" "unprognostic (2.54e-1)" "unprognostic (1.79e-1)" "unprognostic (1.01e-4)" 2.2 1.5 2.0 1.1 2.0 2.5 2.0 2.3 2.9 2.6 1.2 2.5 0.3 2.1 1.0 0.8 2.6 0.8 2.8 1.8 1.9 2.2 2.0 1.7 1.6 1.9 1.7 2.8 0.6 1.7 3.7 0.7 1.8 2.3 0.8 1.5 1.6 0.8 5.9 1.3 2.3 0.8 1.5 3.0 1.7 2.7 1.9 2.9 2.0 8.3 1.3 1.8 1.5 2.2 0.1 0.0 2.0 0.5 0.6 1.0 0.1 0.4 0.9 0.2 0.6 0.1 0.0 0.4 0.6 0.0 0.1 0.0 1.1 0.2 0.5 2.5 0.5 1.0 1.5 0.2 0.9 0.8 0.8 1.8 1.0 0.1 1.2 9.1 0.3 8.9 0.1 1.3 0.0 0.0 1.4 2.3 0.0 0.2 0.4 2.0 0.0 0.9 0.6 0.0 0.1 0.7 0.2 0.0 0.4 1.5 0.4 0.2 0.0 0.1 0.2 0.1 0.1 0.9 0.5 0.6 0.0 2.3 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 2.0 2.3 2.9 1.8 1.9 1.9 1.7 1.8 1.5 1.9 2.2 2.5 6.4 4.5 28.7 2.4 1.1 0.9 1.7 1.2 32.2 2.9 2.0 8.0 4.3 2.3 11.0 39.6 1.2 4.5 3.8 0.0 0.4 2.3 1.3 3.4 2.6 5.4 0.4 38.1 0.2 0.3 2.4 3.1 1.6 1.3 7.7 2.9 6.1 2.2 40.4 40.7 3.3 0.0 4.8 1.7 1.7 3.4 3.5 1.8 7.5 5.2 3.6 1.0 32.6 21.5 0.2 2.0 4.1 2.5 1.2 2.4 1.0 2.2 5.8 0.0 1.9 2.2 7.7 3.2 1.8 1.1 0.8 4.6 4.7 4.0 1.1 SELPLG "CD162, PSGL-1" ENSG00000110876 "Selectin P ligand" Q14242 12 108621895-108633894 "Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 86.6" "Cell type enhanced" "Detected in many" "dendritic cells: 159.7;Kupffer cells: 84.9;Macrophages: 64.8;monocytes: 123.8;NK-cells: 154.5;Plasma cells: 65.1;T-cells: 65.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 136.2;HMC-1: 130.0;JURKAT: 102.2;Karpas-707: 195.1;RPMI-8226: 286.7;U-266/70: 326.8;U-266/84: 214.5" "Low region specificity" "Detected in all" "CAB002431, HPA011256, HPA069062" Enhanced Approved Vesicles NA NA 2700000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "CAB002431: AB_563509, HPA011256: , HPA069062: " "unprognostic (2.32e-2)" "prognostic favorable (1.46e-4)" "unprognostic (3.64e-3)" "unprognostic (1.02e-2)" "unprognostic (6.32e-2)" "prognostic favorable (6.94e-4)" "unprognostic (2.52e-1)" "unprognostic (1.29e-1)" "prognostic favorable (2.92e-4)" "unprognostic (2.26e-1)" "unprognostic (2.12e-2)" "unprognostic (3.24e-1)" "prognostic unfavorable (5.86e-4)" "unprognostic (5.88e-2)" "unprognostic (2.37e-2)" "prognostic favorable (2.74e-4)" "unprognostic (5.44e-2)" 17.5 9.1 12.1 47.4 10.5 21.1 6.9 11.7 12.1 9.2 8.2 9.6 8.6 3.7 2.1 8.6 7.8 17.0 5.0 12.0 14.1 4.0 6.5 40.8 62.2 17.8 13.5 2.8 3.4 4.4 3.0 13.0 16.4 3.3 8.4 0.7 7.0 3.9 2.2 4.7 15.5 11.5 17.0 86.6 11.3 2.2 17.2 52.1 3.4 7.3 30.6 21.5 3.3 24.5 0.5 0.4 1.4 0.8 0.7 1.5 0.8 4.9 4.8 1.8 1.4 0.3 1.9 0.5 1.7 7.4 2.0 0.3 0.1 0.1 1.3 136.2 0.0 45.7 0.2 0.2 0.4 35.1 130.0 1.8 0.5 2.5 0.6 5.0 0.4 102.2 0.8 195.1 6.0 0.0 28.3 18.9 0.2 0.1 1.6 0.3 0.5 286.7 2.9 0.0 0.3 0.0 0.6 0.2 2.2 3.3 0.1 42.6 1.7 2.6 0.8 3.5 1.4 326.8 214.5 6.4 1.5 74.2 1.9 1543.6 297.6 940.2 419.2 509.2 344.3 22.0 396.6 362.9 299.9 22.3 300.3 323.7 1257.2 309.2 762.7 518.3 662.2 1035.5 12.1 10.5 11.7 12.1 12.0 14.1 17.8 13.5 16.4 17.0 17.2 24.5 1.2 3.2 12.4 0.0 11.6 3.4 0.1 0.2 0.0 0.2 0.6 1.4 2.2 4.3 2.7 0.0 0.0 0.5 159.7 0.2 0.0 0.3 8.2 1.8 0.6 2.6 0.0 10.9 0.2 0.2 2.3 2.4 2.6 0.9 29.7 0.4 3.6 2.2 40.1 0.0 0.3 0.0 0.0 84.9 49.6 12.2 0.3 64.8 7.2 15.9 123.8 0.0 154.5 0.0 0.1 0.5 0.0 0.0 65.1 0.1 0.0 0.5 6.4 0.2 0.0 1.2 0.9 0.8 0.5 0.5 1.8 1.0 65.9 0.1 0.0 0.0 SEMA3A "coll-1, Hsema-I, SEMA1, SEMAD, SemD" ENSG00000075213 "Semaphorin 3A" Q14563 7 83955777-84492724 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 22.6" "Cell type enhanced" "Detected in many" "Astrocytes: 58.4;Cone photoreceptor cells: 45.9;Excitatory neurons: 89.7;Rod photoreceptor cells: 66.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 1.5" "Lineage enriched" "Detected in single" 16 "monocytes: 1.5" "Cell line enhanced" "Detected in many" "AF22: 129.3;BJ: 102.9;fHDF/TERT166: 112.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029447, HPA052235" Approved Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA 1600000 "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles Nucleoplasm "HPA029447: AB_10602302, HPA052235: AB_2681770" "unprognostic (1.20e-1)" "prognostic unfavorable (2.69e-5)" "unprognostic (1.51e-1)" "unprognostic (5.82e-2)" "unprognostic (1.37e-2)" "unprognostic (5.98e-3)" "unprognostic (2.92e-3)" "unprognostic (6.05e-3)" "unprognostic (1.13e-1)" "unprognostic (2.48e-1)" "unprognostic (1.46e-1)" "unprognostic (4.44e-2)" "unprognostic (6.18e-12)" "unprognostic (3.26e-2)" "unprognostic (2.41e-2)" "unprognostic (1.61e-2)" "unprognostic (1.47e-4)" 6.8 0.2 3.8 3.8 5.8 0.1 1.5 0.6 3.0 4.4 0.0 9.8 1.4 1.0 2.2 5.8 1.6 5.6 2.5 2.0 0.7 0.4 0.4 2.3 3.3 3.8 0.2 0.4 0.4 0.5 2.1 10.4 4.6 2.9 5.7 22.6 0.4 0.4 0.1 1.1 2.4 4.7 0.6 3.8 2.0 1.2 0.3 0.5 1.7 0.5 1.6 5.4 0.6 4.4 11.8 32.8 129.3 0.1 3.8 3.1 8.4 102.9 60.0 8.5 5.3 11.4 30.7 0.0 4.8 112.0 1.1 57.0 0.3 24.6 11.8 0.0 4.2 0.0 6.0 0.0 3.3 2.6 0.0 3.9 0.0 18.1 4.4 26.2 32.1 0.1 0.1 0.2 3.4 0.6 0.0 0.0 48.6 0.5 11.6 2.3 55.3 3.4 18.5 0.8 9.8 5.2 0.8 0.2 1.1 20.7 0.6 1.1 18.3 11.2 11.6 32.6 15.1 7.6 5.5 0.0 11.5 4.5 22.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 3.8 5.8 0.6 3.0 2.0 0.7 3.8 0.2 4.6 0.6 0.3 4.4 1.0 3.2 1.7 58.4 0.0 0.9 0.0 15.4 0.0 15.1 0.2 0.3 6.0 0.0 22.4 0.0 45.9 0.4 0.3 0.1 0.0 0.1 0.2 2.0 0.7 7.3 0.0 0.0 89.7 2.0 0.2 9.3 0.0 9.0 1.3 3.5 1.8 0.1 1.0 3.3 10.0 0.0 2.0 0.3 2.7 0.2 2.5 0.5 1.8 7.5 0.0 19.6 0.0 9.5 5.8 5.5 0.0 0.0 0.0 0.3 0.0 0.0 15.6 66.3 0.0 1.5 2.1 1.7 1.9 0.4 1.3 0.3 1.1 18.6 0.0 0.2 SEMA3E "coll-5, KIAA0331, M-SemaK, SEMAH" ENSG00000170381 "Semaphorin 3E" O15041 7 83363238-83649139 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 176.3;Alveolar cells type 2: 110.2;Bipolar cells: 75.7;Excitatory neurons: 84.9;Oligodendrocyte precursor cells: 250.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 3.9;SK-BR-3: 19.9;U-2 OS: 6.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029419, HPA063804" Uncertain Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles Nucleoplasm "HPA029419: AB_10602090, HPA063804: AB_2685127" "unprognostic (4.42e-2)" "unprognostic (1.48e-2)" "unprognostic (7.82e-2)" "unprognostic (4.42e-2)" "unprognostic (2.60e-1)" "unprognostic (4.27e-2)" "unprognostic (9.36e-2)" "unprognostic (4.09e-2)" "unprognostic (3.25e-1)" "unprognostic (1.42e-1)" "unprognostic (9.09e-2)" "unprognostic (2.60e-1)" "unprognostic (1.46e-6)" "unprognostic (1.32e-2)" "unprognostic (1.14e-1)" "unprognostic (7.17e-3)" "unprognostic (2.62e-1)" 1.2 0.1 3.1 0.2 2.8 0.0 2.8 0.6 2.3 1.8 0.1 2.1 0.6 1.9 0.3 1.2 0.6 2.3 0.1 5.0 5.3 0.1 0.1 2.2 0.0 1.6 4.3 0.1 0.4 0.0 0.2 0.2 1.3 4.3 1.7 3.9 2.2 3.3 0.2 0.5 1.2 1.1 3.2 0.0 1.3 0.0 4.3 1.7 0.6 1.0 0.1 3.2 0.7 3.7 0.2 1.1 0.2 0.0 0.5 3.1 0.0 0.0 0.2 0.2 0.3 0.0 0.3 0.0 0.0 0.0 0.5 0.0 3.4 0.0 1.3 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.9 0.0 0.0 0.5 0.4 1.1 0.0 2.0 0.0 0.0 0.8 0.1 0.0 0.0 19.9 0.0 3.2 1.6 0.0 0.0 0.7 6.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 2.8 0.6 2.3 5.0 5.3 1.6 4.3 1.3 3.2 4.3 3.7 10.5 176.3 110.2 2.9 0.2 1.1 1.3 1.6 0.0 75.7 19.0 7.5 1.7 18.6 43.2 1.8 0.0 0.8 0.2 0.1 0.0 3.9 1.1 3.8 1.2 10.7 0.0 0.0 84.9 1.1 0.4 21.3 3.1 9.3 24.0 0.2 0.0 0.3 0.1 0.0 12.3 0.0 4.1 1.0 2.1 0.0 0.9 3.6 1.8 1.0 1.0 29.6 0.0 250.3 6.0 6.2 0.0 0.0 0.3 2.6 0.1 0.5 35.7 3.6 0.0 0.8 1.0 0.3 0.6 0.3 0.4 0.3 2.8 0.0 0.0 2.5 SEMA4B "KIAA1745, MGC131831, SEMAC, SemC" ENSG00000185033 "Semaphorin 4B" Q9NPR2 15 90160604-90229679 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 124.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 16.9;naive B-cell: 14.9;neutrophil: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "CAPAN-2: 182.4;RPTEC TERT1: 111.1;RT4: 124.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013372 Approved Approved "Nucleoplasm,Vesicles,Cell Junctions" NA NA 61000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "Nucleoplasm, Vesicles" "HPA013372: AB_1856670" "unprognostic (3.33e-2)" "unprognostic (5.96e-2)" "unprognostic (2.23e-2)" "unprognostic (2.50e-2)" "unprognostic (7.78e-2)" "unprognostic (4.48e-2)" "unprognostic (6.34e-3)" "prognostic unfavorable (1.25e-4)" "unprognostic (2.04e-1)" "unprognostic (9.31e-2)" "unprognostic (1.58e-3)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.33e-8)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (3.57e-2)" "unprognostic (7.09e-2)" 11.9 37.6 20.3 18.0 21.9 9.8 22.5 18.8 21.6 35.1 12.8 50.2 30.2 17.1 8.2 124.4 22.6 17.1 24.9 17.3 21.0 47.7 43.2 20.5 12.0 23.5 24.0 21.6 38.5 18.1 18.6 18.3 21.4 31.4 12.1 27.1 41.2 17.6 7.8 50.9 34.7 13.3 21.0 30.3 32.2 10.7 22.9 13.2 34.2 7.9 13.0 42.2 59.8 26.8 21.2 56.3 4.2 13.2 3.8 2.6 30.4 6.4 13.9 7.8 8.3 7.0 182.4 14.9 69.2 4.7 45.0 97.8 3.7 91.2 6.4 85.4 11.7 19.7 13.5 9.4 15.1 2.6 8.7 10.8 39.1 8.5 17.5 32.5 8.8 4.4 9.6 23.0 4.3 15.6 5.4 8.4 18.7 46.8 51.1 6.4 3.1 33.1 111.1 124.0 13.3 13.5 22.3 35.4 8.5 9.3 24.7 6.0 20.0 6.3 11.4 13.1 14.5 33.0 43.2 7.5 58.8 16.1 6.3 0.0 2.4 0.3 0.9 1.4 0.6 16.9 0.5 0.5 1.2 14.9 0.5 0.6 5.1 0.4 2.8 0.2 0.2 1.5 20.3 21.9 18.8 21.6 17.3 21.0 23.5 24.0 21.4 21.0 22.9 26.8 1.8 16.0 22.5 67.3 29.2 65.0 40.0 51.4 23.9 5.7 29.1 18.9 7.8 8.6 44.6 16.5 25.0 13.9 2.4 47.8 3.9 27.3 0.9 15.6 19.6 4.4 4.2 4.0 23.5 35.5 74.5 6.4 34.1 28.3 0.0 8.6 4.6 16.8 13.3 16.8 28.2 17.5 18.3 6.9 7.5 1.2 13.1 5.5 5.4 2.8 5.3 25.1 1.0 8.0 8.3 44.7 26.1 12.0 8.0 46.9 19.6 4.5 22.6 48.3 19.7 5.7 15.3 0.7 3.2 65.3 57.1 12.4 4.3 5.2 20.2 52.0 SEMA4G "FLJ20590, KIAA1619" ENSG00000095539 "Semaphorin 4G" Q9NTN9 10 100969518-100985871 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 84.6;liver: 102.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 66.4;Gastric mucus-secreting cells: 27.0;Hepatocytes: 60.5;Intestinal goblet cells: 34.6;Paneth cells: 38.5;Proximal enterocytes: 47.6;Undifferentiated cells: 45.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 31.7;CACO-2: 30.5;Hep G2: 113.8;OE19: 69.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038362, HPA077752" Uncertain Uncertain "Vesicles,Lipid droplets" "Intracellular and membrane" NA NA 1300000 "Cluster 37: B-cells - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Lipid droplets" "HPA038362: AB_10669524, HPA077752: " "unprognostic (3.90e-3)" "unprognostic (9.43e-3)" "unprognostic (2.84e-1)" "unprognostic (1.13e-2)" "unprognostic (5.55e-2)" "unprognostic (8.11e-2)" "unprognostic (3.28e-1)" "unprognostic (3.71e-2)" "unprognostic (3.63e-1)" "unprognostic (1.41e-2)" "unprognostic (3.09e-2)" "unprognostic (3.14e-1)" "unprognostic (3.93e-2)" "unprognostic (2.04e-2)" "unprognostic (1.59e-1)" "unprognostic (1.17e-1)" "unprognostic (3.05e-2)" 2.4 12.7 13.1 5.9 10.9 0.4 3.6 18.9 12.3 6.9 12.8 53.6 53.4 3.5 32.1 3.6 5.9 9.0 3.0 10.0 11.6 19.1 102.4 5.8 2.5 11.2 14.4 18.9 31.3 7.3 9.9 3.9 11.5 20.2 84.6 7.3 8.5 3.0 2.6 18.3 41.2 4.6 9.6 3.1 20.9 3.7 17.0 0.8 15.3 0.8 0.9 4.0 5.0 9.9 0.2 31.7 8.0 3.4 5.0 1.6 6.8 1.2 3.4 1.7 1.7 30.5 5.2 0.5 4.2 1.5 0.6 2.1 8.0 1.4 1.4 0.7 4.9 1.7 3.0 113.8 12.5 1.2 1.0 8.3 1.8 1.6 0.9 22.2 4.4 3.5 3.3 0.4 2.5 2.0 0.5 1.2 1.3 69.1 1.8 3.1 0.7 1.5 7.4 1.0 2.5 12.5 1.1 2.1 3.2 8.7 8.7 1.5 3.0 1.0 3.7 0.8 0.3 1.1 0.6 0.5 0.9 1.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.1 10.9 18.9 12.3 10.0 11.6 11.2 14.4 11.5 9.6 17.0 9.9 0.3 3.2 1.1 3.9 1.2 0.0 0.6 0.7 0.6 3.5 2.5 2.0 1.2 20.0 0.2 0.0 0.0 8.8 0.0 66.4 0.0 2.7 0.2 1.6 0.7 0.6 8.5 0.8 3.0 2.6 1.9 2.0 27.0 0.3 0.0 3.4 2.2 60.5 0.9 11.8 14.1 34.6 2.0 3.3 0.0 0.2 2.1 0.2 1.8 0.0 0.0 0.9 0.0 3.5 5.5 2.4 38.5 1.2 0.2 3.0 47.6 6.4 2.4 1.6 0.0 0.1 0.4 1.1 1.9 0.5 0.1 2.9 0.2 12.7 45.9 0.9 SEMA7A "CD108, H-Sema-L, SEMAL" ENSG00000138623 "Semaphorin 7A (John Milton Hagen blood group)" O75326 15 74409289-74433958 "Blood group antigen proteins, CD markers, Plasma proteins, Predicted membrane proteins" "Differentiation, Inflammatory response, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 60.1;retina: 34.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 68.8;Extravillous trophoblasts: 58.8;Granulosa cells: 65.1;Pancreatic endocrine cells: 91.0;Rod photoreceptor cells: 58.3;Syncytiotrophoblasts: 166.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 1.8;eosinophil: 3.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.1" "Cell line enhanced" "Detected in many" "HMC-1: 275.8;hTEC/SVTERT24-B: 108.7;U-251 MG: 166.3;U-87 MG: 92.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008210, HPA042273" Uncertain Uncertain Vesicles NA NA 38000000 "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA008210: , HPA042273: AB_10806234" "unprognostic (2.00e-1)" "unprognostic (2.72e-1)" "unprognostic (2.02e-2)" "unprognostic (5.81e-2)" "unprognostic (6.49e-2)" "unprognostic (8.61e-2)" "unprognostic (2.54e-2)" "unprognostic (4.18e-3)" "unprognostic (1.33e-1)" "unprognostic (1.39e-1)" "unprognostic (5.18e-3)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.45e-11)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (6.25e-2)" "unprognostic (2.57e-2)" 2.0 2.5 4.6 7.0 11.0 9.9 1.9 19.1 14.4 2.2 0.9 2.4 1.5 2.9 0.9 4.8 1.4 1.8 2.3 5.1 8.2 2.8 1.6 8.1 13.2 19.9 11.6 7.8 0.9 1.9 2.7 16.3 22.9 1.8 0.9 34.6 2.2 1.2 2.0 8.5 10.8 1.1 10.6 60.1 3.5 29.5 17.2 9.4 1.3 0.3 12.9 8.2 2.5 20.2 16.7 0.2 4.8 1.4 6.0 20.1 39.7 75.2 30.1 15.5 23.8 6.5 26.6 0.1 4.3 34.2 12.6 4.9 1.5 4.8 16.0 1.3 0.9 30.0 0.1 8.3 1.3 0.9 275.8 14.3 0.2 108.7 6.0 39.0 0.2 2.0 17.5 10.1 51.2 1.4 4.3 9.9 5.2 0.4 11.3 0.6 3.3 4.4 6.5 7.1 0.3 0.5 0.5 13.4 6.1 4.1 1.0 6.0 3.0 28.8 19.2 14.1 166.3 1.8 1.3 0.3 92.4 3.4 1.5 1.8 0.0 3.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 4.6 11.0 19.1 14.4 5.1 8.2 19.9 11.6 22.9 10.6 17.2 20.2 1.8 3.2 0.0 1.0 22.6 0.4 1.6 3.1 0.6 13.7 1.2 1.3 1.4 0.0 4.0 1.8 68.8 25.6 5.2 0.6 0.0 19.8 0.5 4.6 1.5 5.3 0.0 21.7 12.4 13.9 58.8 1.8 1.5 10.6 8.2 65.1 0.7 0.7 7.2 1.7 5.9 0.0 0.0 0.3 12.0 2.5 3.7 4.8 8.8 0.0 28.6 6.8 1.0 4.0 16.3 91.0 0.1 1.9 6.4 3.3 0.1 0.1 2.0 58.3 0.0 0.2 9.0 0.9 0.8 0.2 1.4 166.4 5.7 22.0 0.0 24.4 SENP8 "DEN1, HsT17512, NEDP1, PRSC2" ENSG00000166192 "SUMO peptidase family member, NEDD8 specific" Q96LD8 15 72114258-72143692 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 15.6" "Group enriched" "Detected in many" 11 "Early spermatids: 86.5;Late spermatids: 222.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036273 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" "HPA036273: AB_10669985" "unprognostic (1.83e-2)" "unprognostic (1.78e-1)" "unprognostic (9.85e-4)" "unprognostic (5.43e-2)" "unprognostic (1.49e-1)" "unprognostic (6.09e-3)" "unprognostic (3.06e-2)" "unprognostic (4.35e-2)" "unprognostic (1.06e-1)" "unprognostic (2.04e-1)" "unprognostic (3.11e-2)" "unprognostic (1.19e-1)" "unprognostic (8.46e-12)" "unprognostic (1.24e-1)" "unprognostic (1.12e-1)" "unprognostic (1.85e-2)" "unprognostic (1.54e-2)" 1.1 1.7 2.7 1.1 2.4 2.8 2.0 1.1 3.1 1.7 0.0 1.9 1.8 1.7 3.3 2.3 2.5 1.9 4.0 2.2 2.1 4.4 2.5 1.5 1.5 1.4 1.7 2.4 1.5 2.4 2.1 1.7 1.9 2.1 1.9 4.6 1.6 1.7 6.3 1.6 1.5 1.6 0.4 1.5 2.0 15.6 1.7 1.5 5.0 5.7 1.2 1.7 1.0 2.6 1.5 2.7 4.7 3.8 5.6 6.9 2.7 4.1 2.5 2.2 2.0 2.1 3.4 1.5 5.7 2.4 4.0 3.4 7.4 5.9 3.3 1.6 4.0 2.5 3.7 1.9 3.9 2.8 1.3 3.3 5.8 1.4 6.2 2.9 2.1 4.4 3.7 2.7 5.4 3.8 2.9 3.7 4.0 3.4 2.5 1.9 4.2 3.3 6.0 2.6 5.8 2.0 4.4 3.3 4.2 5.6 5.1 2.1 2.2 4.5 1.7 7.8 2.0 2.2 2.9 1.8 2.1 4.0 3.3 1.1 0.9 0.7 0.8 2.2 1.1 1.9 1.3 1.2 2.9 0.6 1.5 1.8 0.3 3.5 3.2 0.8 1.1 1.0 2.7 2.4 1.1 3.1 2.2 2.1 1.4 1.7 1.9 0.4 1.7 2.6 1.2 6.4 5.3 3.9 0.4 0.3 1.4 2.5 1.2 4.5 2.4 2.4 5.4 1.5 4.5 1.8 4.2 6.7 0.3 1.5 13.7 3.3 86.5 2.5 2.7 1.8 1.2 3.2 4.6 1.7 3.4 2.6 4.1 2.6 0.0 3.4 1.8 1.5 2.1 1.7 6.1 1.5 2.0 2.6 0.6 222.9 1.8 1.7 0.0 2.8 3.8 10.6 0.0 6.0 4.0 1.4 3.2 1.2 0.2 1.7 2.3 8.1 6.0 4.0 0.0 2.3 1.3 10.7 12.6 1.4 0.4 7.8 1.0 3.0 2.2 1.0 SEPSECS "SLA, SLA/LP" ENSG00000109618 "Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase" Q9HD40 4 25120014-25160550 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "RNA-binding, Transferase, tRNA-binding" "Disease variant, Epilepsy, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 26.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 42.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070409 Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 16: U-266 - Nucleosome" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "HPA070409: AB_2686265" "unprognostic (1.83e-1)" "unprognostic (4.09e-2)" "unprognostic (6.37e-3)" "unprognostic (5.86e-2)" "unprognostic (9.63e-2)" "unprognostic (4.61e-3)" "unprognostic (1.82e-3)" "unprognostic (6.33e-2)" "unprognostic (1.24e-1)" "unprognostic (3.34e-1)" "unprognostic (2.52e-1)" "unprognostic (3.56e-2)" "unprognostic (4.45e-3)" "unprognostic (4.64e-2)" "unprognostic (1.65e-1)" "unprognostic (1.16e-2)" "unprognostic (2.13e-3)" 4.7 3.5 2.1 1.7 2.1 0.7 4.4 2.0 3.0 4.2 1.6 5.3 4.8 3.8 2.6 3.2 3.8 2.5 2.7 2.0 2.1 8.2 26.1 3.9 2.1 2.2 2.0 4.9 7.4 3.3 3.0 2.8 2.1 3.4 2.7 1.5 3.9 2.0 3.4 5.2 7.6 1.3 2.0 5.6 5.0 4.0 2.1 5.2 4.8 2.6 2.0 3.8 3.5 2.3 1.7 1.0 3.0 1.3 3.9 4.9 2.5 1.1 1.9 2.6 2.3 0.6 2.6 2.9 1.4 1.0 2.6 1.3 3.5 1.2 2.0 1.9 1.3 2.5 1.0 1.8 4.0 2.0 3.3 4.0 4.2 1.0 3.7 3.1 2.5 4.3 7.0 2.5 1.6 0.7 4.4 6.2 2.1 1.8 2.5 1.3 4.3 1.7 3.7 0.7 1.6 2.4 1.3 1.4 4.7 1.9 1.5 5.5 1.0 1.4 0.7 0.7 1.7 2.3 6.2 1.6 1.4 5.4 1.8 0.0 0.2 0.1 0.1 0.6 0.2 0.0 0.2 0.0 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.1 2.1 2.1 2.0 3.0 2.0 2.1 2.2 2.0 2.1 2.0 2.1 2.3 5.7 0.0 7.2 9.4 6.6 2.4 1.7 3.9 2.8 3.0 5.5 4.3 5.3 22.8 4.3 16.5 0.0 5.5 4.1 10.2 7.9 5.4 30.0 7.3 6.2 6.1 6.1 8.2 5.3 4.7 3.5 4.8 8.2 5.4 3.8 7.9 6.1 42.6 6.1 5.0 7.2 7.7 4.1 8.1 4.5 18.1 3.4 6.6 3.6 14.0 8.0 3.2 4.1 16.1 18.5 5.4 6.0 6.4 6.9 2.7 20.0 20.9 10.2 2.4 0.0 4.9 4.4 26.0 18.3 5.3 3.3 5.9 6.2 7.6 7.8 1.1 SERINC5 "C5orf12, TPO1" ENSG00000164300 "Serine incorporator 5" Q86VE9 5 80111651-80256048 "Predicted membrane proteins, Transporters" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 223.2;Oligodendrocytes: 222.5;Urothelial cells: 254.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 56.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037898, HPA037899" Supported Supported "Vesicles,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "Vesicles, Centrosome" "HPA037898: AB_10673649, HPA037899: AB_2675727" "unprognostic (2.95e-1)" "unprognostic (1.80e-1)" "unprognostic (4.98e-3)" "unprognostic (1.08e-2)" "unprognostic (5.05e-2)" "unprognostic (1.19e-2)" "unprognostic (1.80e-2)" "unprognostic (8.00e-2)" "unprognostic (2.10e-1)" "unprognostic (2.68e-2)" "unprognostic (7.71e-2)" "unprognostic (1.62e-1)" "unprognostic (1.40e-2)" "unprognostic (4.81e-2)" "unprognostic (8.09e-2)" "unprognostic (4.93e-2)" "unprognostic (9.17e-2)" 12.9 34.8 19.2 9.8 31.0 6.3 11.8 27.2 20.7 16.4 17.4 28.3 9.2 9.2 21.1 17.6 16.2 14.2 5.3 18.0 22.7 6.2 45.4 14.1 8.2 26.5 27.6 15.1 7.6 7.1 4.1 16.5 26.8 33.7 29.4 16.3 13.3 7.0 2.7 19.1 9.7 7.6 22.2 4.8 16.6 29.2 28.0 7.9 5.8 2.9 11.4 17.8 11.3 44.4 11.3 19.7 6.6 4.2 8.9 9.5 19.6 9.0 6.0 3.9 4.0 40.0 56.7 1.7 9.0 11.7 9.2 31.7 8.9 23.9 5.6 1.6 4.8 1.4 2.2 21.7 3.3 1.3 4.1 10.8 13.1 10.2 26.0 11.0 7.3 54.0 3.6 9.4 10.4 19.4 22.8 5.5 9.3 15.8 6.8 26.9 5.8 3.0 11.5 54.4 0.4 6.3 8.0 18.5 35.4 33.5 8.2 6.9 8.0 11.3 3.2 11.6 11.3 7.1 3.5 28.1 21.0 3.9 46.9 10.4 9.1 6.7 2.1 4.9 1.6 0.8 18.7 5.7 5.8 1.1 23.3 14.1 5.2 0.6 1.5 1.4 6.6 7.5 19.2 31.0 27.2 20.7 18.0 22.7 26.5 27.6 26.8 22.2 28.0 44.4 48.5 60.9 30.2 46.0 10.5 6.4 56.8 5.6 19.9 3.6 27.7 14.1 8.2 31.5 18.3 16.5 0.0 16.1 12.9 127.4 9.8 26.5 1.7 82.0 29.6 24.5 60.1 24.8 20.9 19.5 25.7 24.9 40.2 157.0 8.2 27.6 35.3 82.7 21.8 3.3 78.3 60.0 4.1 29.2 27.8 7.6 18.3 38.4 5.4 66.5 44.8 65.1 1.0 223.2 222.5 35.4 56.4 39.9 8.7 148.2 27.7 5.1 4.3 5.3 32.9 7.5 17.4 3.1 12.8 44.4 9.8 129.2 37.7 15.2 85.9 254.2 SERPINA1 "A1A, A1AT, AAT, alpha-1-antitrypsin, alpha1AT, PI, PI1" ENSG00000197249 "Serpin family A member 1" P01009 14 94376747-94390693 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Acute phase, Blood coagulation, Hemostasis" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 45 "liver: 34022.4" "Cell type enriched" "Detected in many" 8 "Hepatocytes: 42919.3" "Cancer enriched" "Detected in all" 10 "liver cancer: 3850.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 2482.1;intermediate monocyte: 3411.9;neutrophil: 2823.2;non-classical monocyte: 4518.8" "Group enriched" "Detected in all" 5 "granulocytes: 2823.2;monocytes: 4518.8" "Cell line enriched" "Detected in many" 10 "Hep G2: 4769.1" "Not detected" "Not detected" "Region enriched" "Detected in many" 6 "cerebellum: 130.6" "HPA000927, HPA001292, CAB013211, CAB016648, CAB073396" Enhanced Enhanced Vesicles "Secreted to blood" NA NA 2070000000000 140000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB013211: , CAB016648: AB_1611888, CAB073396: , HPA000927: AB_1844761, HPA001292: AB_1844762" "prognostic favorable (1.61e-5)" "unprognostic (3.37e-1)" "prognostic favorable (5.86e-4)" "unprognostic (1.38e-2)" "unprognostic (1.98e-2)" "unprognostic (5.50e-3)" "unprognostic (3.81e-2)" "unprognostic (6.78e-2)" "unprognostic (2.54e-2)" "unprognostic (7.96e-2)" "unprognostic (1.08e-1)" "unprognostic (4.54e-1)" "unprognostic (1.23e-2)" "unprognostic (1.89e-1)" "unprognostic (1.30e-2)" "unprognostic (1.17e-2)" "unprognostic (1.96e-1)" 49.1 9.7 7.3 225.0 7.1 157.1 100.6 9.1 21.3 105.7 11.1 151.0 278.6 42.3 5.3 10.1 22.4 352.3 12.5 7.3 11.1 621.2 34022.4 570.7 37.0 20.9 14.4 5.4 201.0 5.2 9.1 26.6 15.8 12.6 178.8 2.6 33.6 140.5 3.7 8.2 760.9 75.7 12.2 313.6 282.5 3.0 16.2 15.0 23.0 11.9 25.2 55.8 9.1 16.9 25.9 0.3 0.0 0.5 1.0 0.0 1.5 0.6 1.7 0.6 1.1 187.8 500.8 2.6 15.6 0.0 1.4 1.9 0.0 10.9 1.2 70.1 0.0 4.3 2.0 4769.1 0.3 16.8 2.3 4.1 5.4 0.3 18.5 1.9 0.0 0.0 3.2 0.4 0.0 0.8 1.1 12.1 2.0 5.5 8.0 1.9 16.7 2.4 300.8 3.0 0.6 1.3 6.4 1.6 1.4 0.4 262.1 2.7 1.6 2.1 59.4 1.9 7.1 3.3 1.8 7.0 4.4 41.8 0.6 10.6 2482.1 634.3 5.5 3411.9 6.8 7.7 3.6 4.1 683.6 3.6 4.3 3.6 2823.2 5.3 4518.8 14.9 4.5 2770.7 7.3 7.1 9.1 21.3 7.3 11.1 20.9 14.4 15.8 12.2 16.2 16.9 2.2 35.3 285.9 0.0 137.4 2.3 1.0 36.3 0.0 0.2 100.8 31.5 5.3 4520.9 165.5 150.8 0.0 1.6 3.9 52.0 68.4 3787.9 0.2 70.0 2.8 57.0 12.1 1227.4 0.0 225.8 4.5 3.6 36.2 51.3 1.3 0.1 938.8 42919.3 167.6 0.0 0.0 742.4 30.5 1454.0 74.1 1.1 0.0 413.3 1.8 1.0 291.7 0.3 9.2 0.0 0.0 2161.6 137.0 0.0 1.5 6.8 5270.0 745.9 108.3 0.2 0.0 0.6 17.4 0.0 0.2 0.6 1.7 6.4 75.5 0.0 83.2 6.7 SERPINA4 "KAL, kallistatin, KLST, KST, PI4" ENSG00000100665 "Serpin family A member 4" P29622 14 94561442-94569913 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "liver: 550.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 245.9;Exocrine glandular cells: 93.8;Hepatocytes: 478.5;Pancreatic endocrine cells: 62.1" "Cancer enriched" "Detected in many" 4 "liver cancer: 94.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "Hep G2: 28.4" "Not detected" "Not detected" "HPA003607, HPA068939" Approved Uncertain Vesicles "Secreted to blood" NA NA 14500000000 14000000000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "HPA003607: AB_1079914, HPA068939: " "unprognostic (1.65e-3)" "unprognostic (4.13e-2)" "prognostic favorable (2.95e-4)" "unprognostic (2.09e-3)" "unprognostic (1.99e-3)" "unprognostic (2.82e-1)" "unprognostic (4.03e-3)" "unprognostic (1.02e-2)" "unprognostic (2.24e-4)" "unprognostic (1.08e-1)" "unprognostic (5.45e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 2.8 0.4 41.0 0.0 1.5 53.4 0.0 0.0 0.0 7.3 550.0 0.0 0.0 0.0 0.0 0.0 116.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 5.5 0.0 0.0 0.3 0.0 0.0 0.0 27.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 245.9 0.0 3.7 0.0 0.0 0.0 0.0 11.7 30.0 0.0 3.3 0.3 0.3 0.0 2.7 0.0 93.8 0.0 0.0 5.1 4.5 0.0 0.2 5.3 478.5 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 62.1 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 SERPINB5 "maspin, PI5" ENSG00000206075 "Serpin family B member 5" P36952 18 63476958-63505085 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 216.6;skin 1: 239.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 964.1;Basal prostatic cells: 358.7;Basal respiratory cells: 272.9;Squamous epithelial cells: 535.4;Suprabasal keratinocytes: 1215.3;Urothelial cells: 564.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 124.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1279.3;HBEC3-KT: 425.6;hTCEpi: 875.0;hTERT-HME1: 217.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB009570, HPA019025, HPA019132, HPA020136" Enhanced Supported Vesicles "Intracellular and membrane" NA NA 770000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "CAB009570: AB_2186315, HPA019025: AB_1856726, HPA019132: AB_1856727, HPA020136: AB_1856728" "unprognostic (2.84e-3)" "unprognostic (1.05e-1)" "unprognostic (9.24e-2)" "unprognostic (1.04e-3)" "unprognostic (2.09e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.36e-1)" "unprognostic (3.47e-3)" "prognostic unfavorable (5.71e-6)" "unprognostic (1.28e-1)" "unprognostic (1.84e-6)" "unprognostic (2.57e-1)" "unprognostic (6.58e-2)" "unprognostic (3.14e-1)" "unprognostic (8.38e-2)" 0.6 0.0 0.0 4.3 0.0 0.2 37.1 0.1 0.1 38.5 0.1 4.8 16.7 0.1 0.1 216.6 1.4 2.7 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 9.9 4.5 0.0 37.6 1.7 1.4 239.7 22.1 0.2 0.0 0.0 9.7 2.8 0.0 13.9 0.1 0.0 39.9 90.9 78.7 0.1 80.8 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 73.4 0.1 3.8 0.0 0.1 1279.3 0.0 425.6 0.0 0.0 0.0 0.0 95.8 0.2 0.0 0.0 0.6 0.1 875.0 0.0 217.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.1 179.9 93.4 0.1 0.0 0.2 0.0 95.1 1.4 0.0 60.2 0.3 0.0 0.3 0.2 0.2 0.2 0.0 0.2 0.0 0.2 0.2 0.1 0.2 0.9 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.3 0.0 964.1 358.7 272.9 224.3 0.0 5.1 27.3 0.2 0.0 90.0 3.7 0.0 0.3 0.1 14.2 0.0 0.1 9.0 6.2 0.1 5.4 3.5 0.0 0.3 0.0 0.2 5.8 12.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 10.3 34.6 0.0 57.6 18.6 0.6 1.8 62.2 0.0 0.0 0.0 0.0 0.0 0.1 16.3 51.7 0.0 2.5 85.4 13.5 0.1 85.4 0.0 0.0 0.0 7.1 6.6 2.2 535.4 1215.3 0.1 4.0 0.1 30.6 564.9 SERPIND1 "D22S673, HC-II, HC2, HCF2, HLS2" ENSG00000099937 "Serpin family D member 1" P05546 22 20774113-20787720 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Blood coagulation, Chemotaxis, Hemostasis" "Heparin-binding, Protease inhibitor, Serine protease inhibitor" "Disease variant, FDA approved drug targets, Thrombophilia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "liver: 1253.1" "Cell type enriched" "Detected in some" 25 "Hepatocytes: 283.7" "Cancer enriched" "Detected in many" 80 "liver cancer: 334.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "Hep G2: 208.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "CAB008639, HPA055767" Supported Approved Vesicles "Secreted to blood" NA NA 50000000000 "Cluster 24: B-cells - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "CAB008639: AB_1618010, HPA055767: AB_2682912" "unprognostic (1.68e-1)" "unprognostic (8.27e-2)" "unprognostic (4.40e-2)" "prognostic favorable (4.09e-4)" "unprognostic (5.42e-2)" "unprognostic (1.23e-1)" "unprognostic (1.12e-3)" "unprognostic (1.56e-1)" "unprognostic (1.13e-1)" "unprognostic (1.74e-1)" "unprognostic (1.21e-2)" "unprognostic (2.88e-1)" "unprognostic (3.94e-9)" "unprognostic (2.01e-1)" "unprognostic (4.66e-2)" "unprognostic (8.36e-3)" "unprognostic (1.46e-1)" 0.3 0.2 0.1 0.0 0.8 0.2 0.4 1.7 0.8 1.0 87.7 0.0 0.0 2.0 0.0 0.1 0.9 0.4 1.1 1.7 0.0 0.3 1253.1 2.5 0.0 0.0 0.0 1.8 0.5 10.1 0.8 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 1.2 0.0 0.2 0.4 0.1 0.2 0.0 0.7 0.0 0.0 0.8 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.2 208.2 0.1 0.8 0.5 0.1 0.0 1.6 0.0 0.0 20.4 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.1 2.4 16.5 0.0 0.7 0.0 0.0 3.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.6 0.4 0.1 0.0 0.1 0.1 0.0 0.2 7.2 0.2 13.9 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.5 0.2 0.1 0.1 0.3 0.0 0.5 0.1 0.0 0.1 0.8 1.7 0.8 1.7 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 11.3 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 2.7 1.6 0.0 0.1 2.3 0.0 0.0 1.3 0.0 3.9 283.7 0.1 0.0 0.9 0.0 0.0 6.3 0.0 0.0 1.2 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.5 3.4 0.0 0.0 SERTM1 C13orf36 ENSG00000180440 "Serine rich and transmembrane domain containing 1" A2A2V5 13 36674020-36697839 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.9;endometrium 1: 23.9;fallopian tube: 35.3" "Group enriched" "Detected in some" 7 "Alveolar cells type 1: 9.6;Bipolar cells: 17.9;Endometrial ciliated cells: 5.7;Excitatory neurons: 10.8;Granulosa cells: 14.2;Inhibitory neurons: 17.9" "Cancer enhanced" "Detected in some" "ovarian cancer: 3.7" "Region enhanced" "Detected in many" "hippocampal formation: 18.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HAP1: 1.2;HEK 293: 1.4;NTERA-2: 3.6;SH-SY5Y: 2.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA054814, HPA070485" Enhanced Vesicles NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA054814: AB_2682611, HPA070485: AB_2686272" "unprognostic (8.71e-2)" "unprognostic (2.11e-1)" "unprognostic (5.58e-3)" "unprognostic (4.66e-3)" "unprognostic (4.05e-3)" "unprognostic (5.06e-2)" "unprognostic (2.79e-2)" "unprognostic (1.63e-2)" "unprognostic (1.00e-8)" "unprognostic (2.51e-2)" "unprognostic (5.60e-2)" "unprognostic (4.44e-2)" 6.2 1.3 7.3 0.0 6.0 0.0 0.6 0.1 8.1 12.3 0.0 0.2 0.1 23.9 0.7 0.0 35.3 0.0 0.4 18.9 0.0 0.1 0.0 5.4 0.0 0.0 1.7 6.4 0.3 1.3 11.5 0.0 3.6 0.9 0.0 3.3 0.0 0.6 0.0 0.2 0.0 17.1 0.3 0.0 0.4 0.3 0.4 0.0 9.2 0.0 0.0 0.3 6.7 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 6.0 0.1 8.1 18.9 0.0 0.0 1.7 3.6 0.3 0.4 1.2 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.9 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.7 0.1 0.0 0.0 0.0 10.8 0.0 0.0 1.3 0.0 0.6 0.0 14.2 0.0 0.0 0.0 1.7 17.9 0.0 0.0 0.0 0.4 0.0 0.3 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SETDB1 "ESET, KG1T, KIAA0067, KMT1E, TDRD21" ENSG00000143379 "SET domain bifurcated histone lysine methyltransferase 1" Q15047 1 150926263-150964744 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 6 "U-698: 341.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018142, HPA058484" Uncertain Supported Nucleoplasm,Vesicles Yes No "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm Vesicles "HPA018142: AB_1856757, HPA058484: AB_2683731" "unprognostic (1.07e-1)" "unprognostic (4.08e-1)" "unprognostic (8.02e-2)" "unprognostic (2.24e-3)" "unprognostic (1.65e-2)" "unprognostic (9.57e-2)" "prognostic unfavorable (8.88e-4)" "unprognostic (6.03e-2)" "unprognostic (9.94e-3)" "unprognostic (7.13e-2)" "unprognostic (1.21e-1)" "unprognostic (6.65e-2)" "prognostic unfavorable (4.25e-4)" "unprognostic (1.59e-1)" "unprognostic (3.93e-2)" "unprognostic (3.14e-2)" "unprognostic (1.14e-1)" 13.5 11.3 7.1 15.2 8.2 18.1 16.7 12.8 8.9 14.4 8.7 13.4 12.5 18.1 13.1 11.8 15.3 11.5 8.2 6.7 7.9 11.7 11.5 13.4 19.6 8.2 7.6 19.4 13.3 15.7 8.6 17.7 7.6 11.4 15.5 14.2 12.3 12.2 16.4 14.4 13.7 16.5 6.0 19.9 13.4 25.1 8.4 21.6 15.5 11.7 20.3 13.1 12.7 10.3 22.9 26.3 37.1 24.6 17.5 23.2 61.7 18.6 21.2 26.2 22.2 17.9 31.1 44.9 24.9 20.7 10.4 28.1 35.0 20.0 20.7 21.8 43.3 25.5 27.3 20.8 24.7 45.3 23.2 30.5 22.0 21.8 34.8 26.6 31.2 28.3 43.4 35.6 18.9 44.1 31.6 26.4 51.1 32.1 20.6 36.3 24.3 33.4 20.1 25.9 27.1 49.1 28.4 32.9 22.5 44.5 35.7 60.4 21.2 15.3 15.7 17.0 26.3 36.6 42.3 341.6 15.7 15.7 15.1 6.9 8.3 5.7 5.8 11.6 6.1 6.1 5.3 6.6 9.7 8.3 5.7 5.9 4.8 6.3 8.5 6.5 3.5 4.3 7.1 8.2 12.8 8.9 6.7 7.9 8.2 7.6 7.6 6.0 8.4 10.3 8.5 6.4 14.0 15.3 15.3 5.5 9.3 6.6 10.2 11.0 9.8 10.7 5.5 10.0 7.8 7.3 18.8 13.9 8.8 6.6 3.9 7.6 26.1 10.8 13.3 8.3 3.6 9.2 19.6 5.7 8.5 9.1 10.2 10.7 7.6 17.9 11.4 8.1 9.9 6.7 19.4 9.7 12.2 17.2 5.1 31.0 10.2 13.9 1.8 23.4 14.4 6.2 14.4 15.6 23.5 8.1 9.5 9.8 8.9 8.2 7.6 6.4 11.0 10.4 6.6 10.2 10.3 24.4 15.9 10.9 5.1 10.0 10.2 14.6 10.7 7.8 SEZ6L ENSG00000100095 "Seizure related 6 homolog like" Q9BYH1 22 26169462-26383597 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 60.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 222.1;Inhibitory neurons: 137.7;Oligodendrocyte precursor cells: 586.1" "Group enriched" "Detected in some" 6 "glioma: 14.6;pancreatic cancer: 3.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 5.9;myeloid DC: 5.7;non-classical monocyte: 5.3" "Group enriched" "Detected in many" 58 "dendritic cells: 5.7;monocytes: 5.9" "Group enriched" "Detected in some" 6 "SCLC-21H: 39.9;SH-SY5Y: 10.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045135 Approved Vesicles NA NA 6700000 "Cluster 51: Monocytes - Innate immune response" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA045135: AB_2732518" "unprognostic (1.01e-2)" "unprognostic (1.03e-1)" "unprognostic (1.37e-1)" "unprognostic (4.95e-2)" "unprognostic (4.49e-2)" "unprognostic (6.47e-2)" "unprognostic (4.19e-1)" "unprognostic (1.09e-2)" "unprognostic (5.02e-2)" "unprognostic (7.22e-2)" "unprognostic (1.39e-3)" "unprognostic (7.80e-2)" "unprognostic (2.40e-6)" "unprognostic (4.52e-2)" "unprognostic (3.89e-1)" "unprognostic (2.39e-4)" "unprognostic (3.18e-1)" 0.1 10.0 25.0 0.5 37.5 0.2 0.0 8.9 50.6 1.1 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.1 1.3 60.8 52.0 0.0 0.0 0.2 0.0 24.5 23.6 0.0 1.5 0.0 5.8 0.0 19.0 0.2 0.2 4.5 0.2 0.1 0.1 0.3 0.4 0.3 4.0 0.2 1.4 0.3 49.0 0.9 0.1 0.0 0.0 0.1 0.1 24.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 39.9 10.7 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 5.9 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.5 25.0 37.5 8.9 50.6 60.8 52.0 24.5 23.6 19.0 4.0 49.0 24.9 0.0 0.0 0.0 21.9 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 1.1 0.2 0.0 0.4 222.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 21.9 137.7 0.0 0.0 0.0 2.1 2.0 0.6 1.5 0.0 10.3 3.5 0.7 0.0 586.1 5.5 0.6 0.0 0.4 0.0 0.1 0.0 0.1 0.0 1.2 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 SFXN4 SLC56A4 ENSG00000183605 "Sideroflexin 4" Q6P4A7 10 119140767-119165714 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018028, HPA020872" Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Mitochondria" Vesicles "HPA018028: AB_1856792, HPA020872: AB_1856793" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (3.61e-1)" "unprognostic (1.12e-1)" "unprognostic (1.27e-2)" "unprognostic (9.49e-2)" "unprognostic (1.59e-2)" "unprognostic (1.72e-1)" "unprognostic (6.84e-2)" "unprognostic (4.56e-2)" "unprognostic (8.58e-2)" "unprognostic (2.94e-2)" "unprognostic (1.70e-3)" "unprognostic (4.22e-3)" "unprognostic (1.43e-1)" "unprognostic (6.21e-3)" "unprognostic (3.07e-3)" 13.3 35.9 9.9 10.1 12.5 16.4 14.1 12.8 13.6 14.2 17.0 21.9 20.4 11.1 13.5 19.1 14.3 8.6 33.1 10.2 12.4 24.5 36.4 8.5 14.4 11.3 12.5 16.0 33.7 23.1 21.5 8.8 11.6 18.8 22.7 5.7 27.8 13.2 51.4 11.5 17.3 12.2 10.6 20.9 17.3 11.9 11.3 11.0 24.7 59.3 17.8 16.4 13.8 12.5 26.2 27.6 8.7 41.8 10.4 19.7 33.0 16.3 19.8 21.0 21.8 45.9 43.2 62.6 15.6 14.9 22.4 48.2 57.5 36.3 24.3 33.1 65.7 28.7 18.4 47.3 37.1 49.7 28.8 21.1 34.4 22.0 63.8 19.5 25.0 46.5 45.2 17.5 13.6 29.6 53.8 60.4 11.8 50.2 32.5 51.7 27.1 49.0 24.3 17.3 25.2 13.9 10.8 42.2 61.9 11.1 26.0 28.4 11.5 10.6 21.9 19.8 37.6 42.6 53.0 56.3 16.2 72.6 7.2 2.5 18.1 1.9 6.5 19.5 10.8 12.5 7.9 7.1 21.2 7.0 12.1 9.8 2.2 7.3 15.9 10.6 6.0 11.1 9.9 12.5 12.8 13.6 10.2 12.4 11.3 12.5 11.6 10.6 11.3 12.5 8.0 6.4 5.6 29.0 16.9 12.0 25.8 39.9 23.3 7.9 17.8 18.2 36.2 12.8 19.1 14.7 2.1 37.6 6.2 13.2 58.7 28.4 27.4 7.6 8.9 8.4 18.0 33.6 22.3 23.8 25.8 12.4 14.3 7.9 5.7 28.5 7.1 31.5 29.2 6.7 29.1 24.7 30.5 17.6 5.0 69.3 8.7 13.1 12.4 8.4 11.3 7.7 10.3 22.1 19.5 17.6 12.1 13.5 31.9 28.0 29.8 65.6 13.5 11.3 6.6 22.3 10.6 27.7 15.2 26.9 9.1 21.9 9.2 44.5 45.8 20.5 SGCE DYT11 ENSG00000127990 "Sarcoglycan epsilon" O43556 7 94524204-94656572 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 116.6;Oligodendrocyte precursor cells: 133.2;Oligodendrocytes: 116.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "gdT-cell: 2.1;memory B-cell: 4.4;naive B-cell: 6.6" "Group enriched" "Detected in many" 4 "B-cells: 6.6;T-cells: 2.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074790 Approved "Nucleoplasm,Golgi apparatus,Vesicles,Plasma membrane" Yes No 170000 "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA074790: AB_2686713" "unprognostic (3.16e-3)" "unprognostic (9.06e-2)" "unprognostic (1.20e-1)" "unprognostic (1.20e-3)" "unprognostic (1.12e-1)" "prognostic unfavorable (1.61e-5)" "unprognostic (1.19e-2)" "unprognostic (2.82e-2)" "unprognostic (6.93e-2)" "unprognostic (3.37e-1)" "unprognostic (6.80e-3)" "unprognostic (9.69e-2)" "unprognostic (5.71e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.43e-1)" "unprognostic (2.04e-1)" "unprognostic (2.44e-2)" 43.2 63.4 19.9 9.4 21.6 0.4 36.5 22.1 31.6 45.1 20.9 51.6 8.0 43.2 27.1 13.3 40.7 27.6 38.9 19.6 21.0 19.5 14.4 30.5 16.7 23.2 20.6 92.2 21.5 10.9 30.9 52.7 22.4 18.0 12.8 16.8 21.1 31.6 8.5 8.2 19.2 41.8 21.9 25.1 23.8 18.5 20.4 12.8 23.9 19.8 7.2 35.6 34.6 26.7 13.5 42.5 39.6 61.8 63.7 110.8 7.1 51.3 92.3 40.7 60.4 24.9 78.0 12.8 70.4 86.5 83.7 9.4 60.0 21.6 49.1 2.2 32.7 1.4 36.9 28.3 44.0 4.3 0.0 95.5 31.1 64.8 79.3 104.9 30.8 0.0 0.1 93.7 43.5 42.6 0.0 0.0 32.8 8.0 29.0 19.8 51.0 25.8 78.6 13.6 26.2 20.8 0.0 52.2 65.1 44.2 17.6 0.8 0.0 131.1 45.1 11.8 81.7 50.8 67.9 14.8 51.4 0.2 74.2 0.7 0.0 0.1 2.1 0.0 0.8 4.4 0.6 1.0 0.0 6.6 0.2 0.7 0.3 1.0 0.1 0.2 0.2 0.3 19.9 21.6 22.1 31.6 19.6 21.0 23.2 20.6 22.4 21.9 20.4 26.7 39.2 70.5 33.3 66.9 6.1 5.0 18.4 16.8 1.8 18.6 9.7 44.4 18.6 30.0 28.3 20.2 4.2 90.2 1.4 0.0 5.9 42.5 1.6 4.0 17.1 18.8 1.2 0.4 85.2 4.3 26.1 116.6 1.5 6.6 2.5 37.3 58.2 11.2 6.3 20.2 68.5 0.1 12.2 2.5 7.3 3.7 75.5 1.4 51.6 15.9 0.0 31.5 0.0 133.2 116.3 2.1 0.0 58.3 2.6 5.5 0.0 14.1 13.7 30.3 85.5 68.0 60.7 17.1 13.0 0.9 4.0 82.8 2.7 44.0 0.0 2.2 SGK3 "SGK2, SGKL" ENSG00000104205 "Serum/glucocorticoid regulated kinase family member 3" Q96BR1 8 66712734-66862022 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 49.0" "Cell type enhanced" "Detected in many" "Breast glandular cells: 56.0;monocytes: 53.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 28.4" "HPA006699, HPA027146" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 6: T47d - Mammary gland" "Cluster 35: Glandular cells - Unknown function" Vesicles Nucleoplasm "HPA006699: , HPA027146: AB_1856745" "prognostic favorable (5.52e-6)" "prognostic favorable (8.28e-4)" "unprognostic (8.52e-3)" "unprognostic (1.10e-2)" "unprognostic (3.75e-1)" "unprognostic (1.37e-2)" "unprognostic (2.32e-1)" "unprognostic (1.69e-3)" "unprognostic (9.51e-2)" "unprognostic (8.86e-3)" "prognostic favorable (9.65e-4)" "unprognostic (1.94e-2)" "unprognostic (8.95e-2)" "unprognostic (4.55e-3)" "unprognostic (1.77e-1)" "unprognostic (1.01e-1)" "unprognostic (5.29e-3)" 5.2 5.3 13.4 9.8 25.7 8.5 24.1 21.3 16.9 10.5 36.0 10.3 8.9 8.0 8.6 7.6 6.9 7.5 5.4 14.6 17.3 14.7 13.6 10.0 7.8 29.4 21.6 9.1 15.6 28.3 6.2 5.7 28.3 7.4 10.3 2.4 7.0 7.1 2.9 13.3 11.3 5.3 19.3 8.9 7.5 9.4 20.9 5.8 17.5 3.5 6.9 5.0 5.7 49.0 14.2 3.7 0.6 2.4 3.9 6.5 7.7 8.1 7.4 4.2 5.1 6.1 8.6 10.2 2.2 7.7 13.6 4.9 7.3 5.5 5.4 5.3 11.7 9.7 2.6 6.7 4.1 8.9 10.5 2.9 3.7 1.7 7.9 4.3 7.4 7.4 1.5 4.6 10.0 2.4 6.2 5.8 1.9 8.5 5.0 11.7 5.3 7.6 6.4 3.3 2.9 2.2 3.4 6.5 14.4 6.0 28.4 16.9 9.0 4.4 3.9 3.9 3.4 6.1 12.8 12.7 4.5 14.2 4.9 21.1 15.0 5.1 8.7 9.9 13.8 4.7 8.8 8.0 13.8 6.4 8.7 7.1 2.0 7.2 5.1 8.9 5.7 9.0 13.4 25.7 21.3 16.9 14.6 17.3 29.4 21.6 28.3 19.3 20.9 49.0 20.7 6.4 28.1 0.0 12.5 13.3 8.1 3.3 8.6 1.7 56.0 30.5 7.6 7.2 8.5 11.0 18.8 9.2 24.9 13.3 15.6 7.0 0.9 16.7 6.6 15.3 16.2 10.3 0.0 18.2 1.4 8.9 6.6 12.3 15.2 11.0 17.5 20.7 22.9 0.0 0.0 9.3 8.2 41.9 14.3 2.2 4.1 42.6 8.8 0.0 53.4 3.8 19.6 0.0 0.0 14.8 8.4 7.9 18.3 9.3 14.0 36.8 15.4 1.7 0.0 5.9 4.2 5.9 13.7 9.9 15.8 4.8 19.4 5.2 10.4 5.3 SH3BGRL MGC117402 ENSG00000131171 "SH3 domain binding glutamate rich protein like" O75368 X 81202102-81298547 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051248 Approved Approved Vesicles NA NA 13000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA051248: AB_2681405" "unprognostic (3.02e-3)" "unprognostic (4.25e-2)" "unprognostic (4.89e-2)" "unprognostic (3.15e-2)" "unprognostic (1.46e-1)" "unprognostic (1.39e-1)" "unprognostic (2.25e-2)" "unprognostic (3.20e-2)" "unprognostic (1.23e-1)" "unprognostic (1.51e-1)" "unprognostic (1.78e-1)" "unprognostic (4.62e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (4.08e-4)" "unprognostic (2.12e-1)" "unprognostic (3.75e-1)" "unprognostic (1.73e-1)" 112.1 120.0 92.4 101.1 92.4 176.7 170.8 98.1 126.3 146.2 94.3 180.8 87.6 208.5 148.8 130.4 112.3 149.1 61.1 88.0 108.2 126.0 62.6 133.0 154.9 104.8 95.6 130.7 81.3 112.3 83.5 86.4 105.2 153.1 108.5 24.9 112.5 284.9 16.5 67.1 98.1 231.7 104.4 144.4 87.0 54.3 96.1 145.1 104.7 50.2 126.8 178.3 76.0 116.3 1.0 38.2 133.4 154.1 172.1 232.0 9.2 83.4 158.3 30.1 61.1 12.5 114.6 113.7 70.1 122.9 42.4 20.7 95.9 60.0 48.0 98.7 33.3 151.2 59.7 7.4 41.6 107.3 286.0 135.6 42.9 42.4 37.6 231.4 133.8 75.9 53.0 279.6 165.9 53.9 117.0 138.7 105.2 1.4 62.3 102.0 60.9 60.8 155.7 52.8 0.4 58.5 0.1 4.2 77.9 88.0 44.8 321.2 136.9 82.7 34.1 76.4 35.0 64.3 60.6 105.6 95.1 215.9 62.9 793.9 358.5 570.7 124.9 477.3 134.8 236.3 154.7 147.8 306.2 207.4 140.8 148.8 126.7 183.0 560.5 148.0 257.5 462.3 92.4 92.4 98.1 126.3 88.0 108.2 104.8 95.6 105.2 104.4 96.1 116.3 191.3 112.2 92.6 73.8 216.1 126.3 131.5 150.4 83.1 16.2 174.6 150.2 19.7 72.9 106.4 121.4 0.0 7.1 183.9 33.2 344.4 86.9 6.3 74.9 120.0 130.7 93.3 172.9 62.8 74.7 6.0 152.4 63.2 62.6 219.7 92.8 139.9 17.8 431.4 5.0 82.4 87.0 109.9 400.9 430.7 19.2 174.3 379.0 147.7 102.1 459.0 154.2 224.6 82.9 54.3 48.0 104.2 314.1 114.4 83.5 91.2 214.3 113.6 8.5 263.0 132.4 308.8 4.5 5.9 76.0 119.5 5.7 163.4 205.9 90.3 146.4 SH3BP5L KIAA1720 ENSG00000175137 "SH3 binding domain protein 5 like" Q7L8J4 1 248810446-248825915 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 7.7;eosinophil: 4.1;neutrophil: 4.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 7.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038067, HPA038068" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA038067: AB_2675814, HPA038068: AB_10670651" "unprognostic (2.48e-1)" "unprognostic (1.62e-1)" "unprognostic (5.53e-3)" "unprognostic (4.41e-1)" "unprognostic (2.78e-1)" "unprognostic (2.27e-3)" "unprognostic (1.99e-3)" "unprognostic (5.84e-2)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (2.87e-3)" "unprognostic (1.50e-2)" "unprognostic (1.13e-1)" "unprognostic (2.05e-2)" "unprognostic (1.55e-1)" "unprognostic (4.99e-2)" "unprognostic (4.66e-2)" 9.6 10.5 18.0 10.1 18.7 9.0 7.7 17.3 21.0 8.8 13.9 12.2 13.5 10.5 7.8 15.8 10.0 8.0 14.1 19.4 15.8 9.5 10.5 9.2 11.3 17.0 16.7 8.6 10.0 12.0 5.9 11.4 16.9 9.1 7.3 5.3 11.9 11.6 30.6 18.4 12.4 9.9 15.8 12.3 9.9 9.5 17.1 13.8 8.1 17.8 10.2 9.0 9.1 18.3 23.2 14.7 18.5 21.2 25.7 17.1 24.6 51.1 17.4 29.2 21.8 14.3 20.0 11.6 29.7 44.1 7.3 24.6 17.9 22.1 15.0 25.4 6.3 18.6 16.4 11.9 15.8 20.4 21.9 14.4 23.4 33.0 12.9 20.7 19.6 21.4 33.0 12.0 20.2 7.9 19.7 16.5 32.4 25.5 36.9 21.9 13.0 23.5 20.5 10.6 21.1 29.2 15.6 19.3 17.9 14.0 21.0 42.4 27.5 36.9 15.7 14.7 80.2 30.5 34.3 10.5 26.8 23.5 15.4 7.7 1.2 4.1 0.7 0.8 0.7 0.6 1.0 0.6 1.1 0.6 0.3 0.3 4.6 0.3 0.3 0.4 0.2 0.8 18.0 18.7 17.3 21.0 19.4 15.8 17.0 16.7 16.9 15.8 17.1 18.3 5.2 0.0 2.0 5.9 4.3 4.6 2.1 2.9 4.0 8.3 6.1 5.0 9.4 1.5 2.3 11.0 0.0 9.6 4.7 15.1 1.9 8.8 1.3 10.5 5.4 6.0 7.7 6.9 6.5 6.0 5.2 4.9 7.7 6.1 0.0 9.0 6.1 10.0 6.0 8.4 5.7 8.4 2.0 5.3 4.5 1.0 4.4 5.6 3.6 3.7 7.1 4.7 6.2 6.0 6.4 10.6 8.1 5.7 5.4 3.0 13.8 9.2 5.1 3.5 0.0 3.7 5.8 8.8 7.0 7.0 4.7 11.4 6.3 5.4 7.3 3.3 SH3RF1 "KIAA1494, POSH, RNF142, SH3MD2" ENSG00000154447 "SH3 domain containing ring finger 1" Q7Z6J0 4 169094259-169270956 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 146.3;Oligodendrocytes: 213.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.2;myeloid DC: 2.5;non-classical monocyte: 6.7" "Group enriched" "Detected in many" 15 "dendritic cells: 2.5;monocytes: 6.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074783 Approved Supported "Vesicles,Intermediate filaments" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "Intermediate filaments" "HPA074783: AB_2732268" "unprognostic (4.14e-1)" "unprognostic (4.67e-2)" "unprognostic (1.23e-1)" "unprognostic (7.83e-2)" "unprognostic (1.02e-1)" "unprognostic (1.30e-2)" "unprognostic (1.29e-1)" "unprognostic (2.65e-1)" "unprognostic (8.44e-2)" "unprognostic (9.58e-2)" "unprognostic (4.77e-3)" "unprognostic (7.88e-2)" "prognostic favorable (5.51e-8)" "unprognostic (4.43e-2)" "unprognostic (1.63e-1)" "unprognostic (5.99e-2)" "unprognostic (1.77e-1)" 9.8 3.7 8.7 4.4 10.0 3.4 8.2 7.6 13.1 5.7 5.9 15.1 13.8 4.3 5.7 5.9 5.6 11.9 5.7 18.2 8.6 12.2 8.0 9.4 3.3 8.8 9.7 8.5 10.4 3.7 3.7 7.4 9.4 14.3 13.6 2.4 15.8 8.4 9.4 5.1 13.1 4.0 8.2 3.9 24.7 6.1 9.5 2.0 19.9 10.0 3.2 9.3 4.4 13.0 15.2 12.2 11.0 31.9 11.5 14.3 14.1 40.5 19.7 30.0 13.8 12.5 17.8 0.0 1.9 43.1 8.1 9.8 8.9 16.2 32.4 0.1 5.2 8.7 27.4 6.5 26.0 3.1 0.3 8.5 8.6 25.7 19.9 37.3 18.7 3.3 0.1 0.0 27.8 6.0 3.1 2.9 5.6 19.2 10.5 4.5 3.6 0.6 13.6 11.8 8.3 9.9 10.4 15.7 4.2 4.7 5.2 1.3 17.1 14.2 11.0 23.6 14.7 1.1 0.0 0.1 16.0 3.0 17.3 0.0 1.0 0.0 0.0 4.2 0.0 0.3 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.2 6.7 0.2 0.0 0.6 8.7 10.0 7.6 13.1 18.2 8.6 8.8 9.7 9.4 8.2 9.5 13.0 28.0 64.1 37.7 146.3 3.4 34.3 48.3 11.9 13.6 3.5 21.1 15.6 11.2 44.3 34.4 27.6 0.0 12.7 0.4 69.3 11.7 42.2 5.5 28.5 14.2 13.0 31.3 2.1 54.9 63.7 22.1 16.5 65.7 46.5 10.2 5.6 11.4 12.4 7.4 0.0 54.9 27.1 12.2 9.3 5.3 3.5 12.2 11.1 3.6 52.5 3.9 11.3 0.0 89.5 213.0 68.4 37.2 12.0 2.4 63.2 28.9 18.4 31.7 1.2 65.7 24.1 36.9 5.4 10.7 9.4 12.6 13.1 1.7 6.5 34.4 72.0 SHANK2 "CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3" ENSG00000162105 "SH3 and multiple ankyrin repeat domains 2" Q9UPX8 11 70467854-71252577 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 31.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 153.5;Horizontal cells: 136.3;Inhibitory neurons: 167.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "amygdala: 7.7;basal ganglia: 7.5;cerebral cortex: 9.3;hippocampal formation: 9.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 11.5;Karpas-707: 17.5;RT4: 15.9;T-47d: 16.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008174, HPA017220" Approved Approved "Nuclear speckles,Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane" "Nuclear speckles" "HPA008174: AB_1856822, HPA017220: " "unprognostic (3.08e-1)" "unprognostic (1.31e-3)" "unprognostic (1.79e-1)" "unprognostic (1.51e-2)" "unprognostic (1.51e-1)" "unprognostic (7.23e-5)" "unprognostic (1.24e-1)" "unprognostic (6.67e-2)" "unprognostic (1.83e-2)" "unprognostic (8.42e-2)" "unprognostic (4.87e-2)" "unprognostic (4.01e-1)" "prognostic favorable (1.94e-6)" "unprognostic (3.46e-2)" "unprognostic (2.34e-1)" "unprognostic (4.03e-2)" "unprognostic (4.80e-2)" 1.3 1.2 7.7 0.5 7.5 0.0 4.5 0.2 9.3 1.3 31.7 2.4 1.5 1.0 2.2 3.4 5.1 0.8 0.0 9.5 0.0 4.9 3.8 3.7 0.1 0.0 0.0 0.1 7.5 0.1 2.2 1.9 0.0 3.2 2.0 5.5 9.8 1.8 0.0 0.9 1.3 0.4 0.0 1.1 3.0 0.9 1.0 0.0 6.0 0.0 0.4 1.1 0.3 0.9 0.5 7.4 4.1 0.0 0.6 0.4 4.5 0.7 0.3 0.0 0.0 6.6 3.1 6.2 2.2 0.0 0.1 1.1 0.0 4.8 0.0 0.0 0.2 0.0 0.0 11.5 0.0 0.0 1.9 0.1 1.8 0.0 0.0 1.6 0.0 0.1 0.0 17.5 1.7 10.5 0.0 0.1 3.5 10.2 0.3 0.0 9.9 8.2 5.2 15.9 3.5 1.1 0.0 8.4 0.0 5.2 16.4 0.0 0.0 0.0 1.5 0.1 0.0 0.1 0.6 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 7.5 0.2 9.3 9.5 0.0 0.0 0.0 0.0 0.0 1.0 0.9 8.0 41.7 17.0 21.5 0.2 0.0 3.2 3.2 0.6 17.9 26.9 13.0 3.7 11.5 5.4 7.3 0.0 12.8 0.4 3.2 3.9 8.4 1.7 30.0 3.2 1.3 0.0 0.0 153.5 2.2 2.9 1.8 10.2 13.0 2.5 1.2 0.4 21.9 1.2 136.3 167.5 7.9 8.2 0.0 0.3 2.1 0.0 0.4 5.4 14.0 0.0 4.6 0.0 41.7 5.3 10.7 2.7 0.7 0.4 10.9 0.6 10.8 23.3 1.0 0.0 0.3 1.3 0.7 0.9 1.3 0.6 14.6 0.3 0.1 5.5 4.0 SHISA2 "bA398O19.2, C13orf13, hShisa, PRO28631, TMEM46, WGAR9166" ENSG00000180730 "Shisa family member 2" Q6UWI4 13 26044597-26052016 "Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 12.4;skeletal muscle: 14.2;thyroid gland: 21.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 13.1;Basal prostatic cells: 14.6;Breast glandular cells: 24.1;Oligodendrocytes: 10.9;Urothelial cells: 19.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 25.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 26.7;JURKAT: 20.8;LHCN-M2: 18.7;NTERA-2: 15.5;RH-30: 46.3;U-2197: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA049752, HPA050172" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "Nuclear bodies, Vesicles" "HPA049752: , HPA050172: AB_2681041" "unprognostic (2.08e-2)" "unprognostic (3.00e-1)" "unprognostic (2.41e-1)" "unprognostic (9.71e-2)" "unprognostic (6.09e-2)" "unprognostic (2.52e-1)" "unprognostic (1.20e-1)" "prognostic favorable (3.30e-4)" "unprognostic (4.03e-2)" "unprognostic (3.10e-1)" "unprognostic (7.45e-2)" "unprognostic (2.17e-2)" "prognostic favorable (2.43e-4)" "unprognostic (5.56e-3)" "unprognostic (2.09e-1)" "unprognostic (3.46e-1)" "unprognostic (1.51e-2)" 0.5 0.0 1.1 0.2 2.3 0.1 12.4 1.5 2.0 1.7 0.9 0.1 0.7 0.1 7.8 0.2 0.2 0.5 0.2 2.0 1.5 4.7 0.0 4.3 0.5 1.9 1.5 0.3 0.3 0.1 1.6 0.0 1.6 0.5 0.1 0.0 2.7 0.3 14.2 1.1 0.7 0.1 2.2 0.2 2.1 1.2 1.6 2.5 21.0 1.2 0.7 0.7 0.0 5.4 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.8 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.4 4.2 1.4 0.0 0.0 1.7 26.7 1.0 20.8 0.0 0.0 18.7 1.2 2.3 0.5 15.5 8.4 8.2 0.0 46.3 0.3 1.7 6.5 0.4 0.0 0.4 0.0 5.4 2.6 0.7 0.2 1.6 0.1 0.7 30.4 7.0 0.0 0.0 0.0 0.0 0.0 4.1 0.8 0.1 0.5 0.1 0.2 0.2 0.1 0.4 0.1 0.0 0.2 1.0 1.6 0.4 0.2 0.3 0.1 0.2 0.1 1.1 2.3 1.5 2.0 2.0 1.5 1.9 1.5 1.6 2.2 1.6 5.4 4.7 0.0 13.1 0.0 0.4 5.4 14.6 2.3 0.6 0.0 24.1 6.2 0.5 0.0 1.5 3.7 0.0 0.3 0.3 0.1 0.0 6.0 2.6 1.0 0.5 5.1 0.0 0.0 0.0 0.2 0.3 2.8 3.1 2.5 0.0 2.4 1.1 0.0 0.8 0.0 1.0 0.1 8.2 0.3 2.3 1.0 0.0 0.3 1.8 0.0 0.0 0.0 0.0 0.5 10.9 1.2 0.0 0.4 0.2 3.9 0.0 0.3 1.1 0.0 0.0 7.6 1.6 0.7 5.1 0.4 1.7 0.1 1.1 0.7 0.0 19.6 SHISA9 ENSG00000237515 "Shisa family member 9" B4DS77 16 12901598-13240416 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.8" "Group enriched" "Detected in many" 17 "Excitatory neurons: 265.0;Inhibitory neurons: 427.9;Oligodendrocyte precursor cells: 636.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "EFO-21: 48.5;LHCN-M2: 40.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072399 Approved Vesicles,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Cytosol" "HPA072399: AB_2686517" "unprognostic (1.88e-2)" "unprognostic (3.04e-2)" "unprognostic (2.74e-1)" "unprognostic (1.69e-5)" "unprognostic (2.23e-2)" "unprognostic (2.03e-2)" "unprognostic (5.90e-5)" "unprognostic (1.50e-2)" "unprognostic (1.98e-1)" "unprognostic (1.19e-2)" "unprognostic (3.66e-1)" "unprognostic (1.38e-1)" "prognostic favorable (1.53e-4)" "unprognostic (1.19e-1)" "unprognostic (2.09e-1)" "unprognostic (6.66e-2)" "unprognostic (1.26e-2)" 0.5 2.8 12.5 0.8 12.7 1.3 0.6 0.0 14.8 0.3 0.0 3.2 0.8 0.4 1.1 0.5 0.2 0.4 0.6 10.9 6.3 1.9 0.6 0.2 0.4 6.9 5.9 0.4 0.6 0.1 0.9 0.4 6.2 4.2 0.9 3.7 0.9 0.7 1.5 0.9 0.9 0.6 1.7 0.4 0.5 0.7 11.0 0.1 2.1 0.0 0.3 0.2 0.2 4.2 0.8 0.4 0.6 0.5 0.2 0.2 0.5 0.4 0.0 0.0 0.0 0.3 0.5 0.5 48.5 0.1 0.7 0.6 0.1 0.2 0.1 0.6 0.2 0.6 0.9 0.3 0.1 0.6 0.6 1.5 0.1 0.1 3.3 0.4 0.1 0.6 0.4 1.0 40.5 5.5 0.4 0.7 10.2 0.7 0.5 0.6 0.4 0.3 10.9 1.5 10.1 0.5 0.4 1.4 0.4 4.4 0.9 0.4 0.4 0.6 5.8 0.6 0.4 0.9 1.0 0.5 0.4 0.3 1.0 0.8 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.0 12.5 12.7 0.0 14.8 10.9 6.3 6.9 5.9 6.2 1.7 11.0 4.2 0.0 25.6 20.1 5.2 0.1 0.1 0.5 0.2 0.0 0.8 1.7 0.8 1.3 1.5 7.0 1.8 0.0 0.1 0.0 0.3 1.9 1.4 4.8 0.1 0.5 1.1 0.0 0.0 265.0 0.0 0.0 2.0 0.0 0.3 11.4 0.0 0.0 0.0 0.0 0.0 427.9 0.3 0.0 0.0 0.4 3.4 0.3 1.0 0.0 5.6 0.0 0.5 0.0 636.3 4.9 0.1 2.3 0.0 0.0 1.8 0.0 1.3 11.8 0.3 0.0 6.6 0.2 0.5 2.0 0.0 0.1 0.1 1.3 0.0 0.8 0.6 SHISAL1 KIAA1644 ENSG00000138944 "Shisa like 1" Q3SXP7 22 44243665-44312951 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.2;endometrium 1: 33.6;smooth muscle: 29.3" "Cell type enriched" "Detected in single" 6 "Endometrial stromal cells: 4.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SiHa: 36.2;U-2197: 80.8;U-87 MG: 46.3;WM-115: 27.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051178 Uncertain Approved Vesicles,Cytosol No No "Cluster 57: Non-specific - Angiogenesis" "Cluster 18: U-2197 - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Vesicles, Cytosol" "HPA051178: AB_2681374" "unprognostic (4.07e-3)" "unprognostic (9.01e-2)" "unprognostic (1.83e-1)" "unprognostic (1.14e-1)" "unprognostic (6.54e-2)" "unprognostic (1.22e-1)" "unprognostic (7.79e-2)" "unprognostic (2.64e-2)" "unprognostic (8.10e-3)" "unprognostic (1.93e-3)" "unprognostic (1.33e-1)" "unprognostic (1.99e-1)" "unprognostic (1.51e-7)" "unprognostic (1.48e-2)" "unprognostic (2.41e-1)" "unprognostic (1.99e-4)" "unprognostic (1.10e-4)" 1.0 1.8 18.6 1.2 17.2 0.0 0.2 0.0 21.4 16.6 0.0 18.7 1.9 33.6 0.4 1.6 4.5 3.1 0.9 18.0 15.3 0.5 0.1 0.3 0.4 10.8 17.8 1.0 0.8 0.1 2.6 0.5 2.4 3.7 2.0 5.6 0.3 11.0 0.0 0.7 2.4 29.3 0.3 0.1 1.6 1.1 43.2 2.6 0.4 0.1 0.7 11.9 5.2 2.8 0.0 0.3 3.5 1.2 0.0 0.0 0.0 1.0 2.3 2.4 1.4 0.0 0.0 0.0 0.0 2.3 14.5 0.0 5.0 0.3 0.3 0.0 2.3 0.0 13.0 0.0 0.0 0.0 0.0 0.0 0.4 4.5 1.8 11.2 0.5 0.0 0.0 0.1 0.1 0.0 0.4 0.0 3.3 0.0 0.8 0.0 0.0 0.1 0.0 0.0 12.9 0.0 36.2 0.1 0.2 0.4 0.0 0.3 0.1 13.1 2.0 80.8 0.5 0.0 0.0 0.0 46.3 0.0 27.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.6 17.2 0.0 21.4 18.0 15.3 10.8 17.8 2.4 0.3 43.2 2.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.3 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 SHLD1 "C20orf196, FLJ25067, RINN3" ENSG00000171984 "Shieldin complex subunit 1" Q8IYI0 20 5750393-5864395 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 12.9;dendritic cells: 13.1;Distal tubular cells: 19.6;Exocrine glandular cells: 14.2;Hofbauer cells: 17.0;Pancreatic endocrine cells: 11.7;Proximal tubular cells: 11.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 55.7;U-698: 45.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040749 Approved Approved "Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum, Golgi apparatus, Vesicles" "HPA040749: AB_10673093" "unprognostic (2.03e-1)" "unprognostic (1.91e-1)" "unprognostic (2.08e-2)" "unprognostic (4.20e-3)" "unprognostic (6.15e-2)" "unprognostic (1.66e-1)" "unprognostic (1.72e-3)" "unprognostic (6.66e-2)" "unprognostic (9.04e-3)" "unprognostic (1.67e-2)" "unprognostic (1.44e-2)" "unprognostic (7.59e-3)" "unprognostic (1.63e-1)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (1.76e-1)" "prognostic favorable (4.05e-5)" 4.0 9.7 5.0 6.2 5.8 16.7 5.3 7.2 6.1 5.1 4.6 5.1 9.1 3.8 5.3 5.4 3.9 4.4 8.6 4.9 5.8 6.7 3.0 4.8 14.3 5.6 5.3 5.1 5.2 2.4 6.0 3.0 6.3 6.3 4.9 4.0 8.4 3.7 12.0 4.1 7.1 2.6 4.6 9.9 4.7 3.1 5.4 13.3 6.6 7.7 12.1 4.5 4.7 6.4 9.2 9.6 4.6 2.3 2.8 2.8 2.3 2.5 4.5 3.1 4.3 4.5 9.4 33.3 6.3 2.5 2.5 4.1 2.8 6.1 3.6 10.3 3.4 12.9 1.4 18.2 6.2 16.2 5.7 3.3 7.2 4.7 3.1 3.0 6.4 8.7 17.8 13.9 5.9 3.5 20.4 55.7 6.3 10.3 5.2 16.5 7.1 15.1 5.0 4.5 8.2 7.4 4.6 4.7 10.0 2.6 3.9 13.2 4.3 3.6 5.4 3.5 5.4 8.7 16.6 45.8 1.8 13.9 6.4 21.7 12.4 22.5 21.3 14.8 16.4 27.7 25.2 21.5 12.7 33.1 22.9 17.2 4.9 23.5 16.9 15.1 31.5 13.0 5.0 5.8 7.2 6.1 4.9 5.8 5.6 5.3 6.3 4.6 5.4 6.4 9.2 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 6.4 8.6 0.0 0.0 0.0 12.9 0.0 7.5 13.1 0.0 19.6 7.9 0.0 6.4 4.4 2.8 0.0 0.0 0.0 14.2 7.5 1.7 0.0 5.2 0.0 7.3 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 1.6 0.0 0.0 0.0 0.0 11.7 0.0 0.0 2.3 0.0 0.0 11.7 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 5.9 6.4 5.0 0.0 0.0 SHOC1 "C9orf84, FLJ32779, MZIP2, Zip2" ENSG00000165181 "Shortage in chiasmata 1" Q5VXU9 9 111686173-111795008 "Predicted intracellular proteins, Predicted membrane proteins" Meiosis "DNA-binding, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 17.1" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.0;Endothelial cells: 1.0" "Cancer enhanced" "Detected in some" "cervical cancer: 0.8" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 11 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Cell line enriched" "Detected in some" 4 "U-2 OS: 21.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA032108 Approved Vesicles,Cytosol NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 43: Testis - Unknown function" "Cluster 9: U-2 OS - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" "Vesicles, Cytosol" "HPA032108: AB_10669884" "unprognostic (2.63e-1)" "unprognostic (1.83e-4)" "unprognostic (9.12e-2)" "unprognostic (3.17e-1)" "unprognostic (2.28e-1)" "unprognostic (1.13e-1)" "unprognostic (9.05e-2)" "unprognostic (5.02e-2)" "unprognostic (6.22e-2)" "unprognostic (1.65e-1)" "unprognostic (8.14e-2)" "unprognostic (2.30e-1)" "unprognostic (8.33e-5)" "unprognostic (6.93e-2)" "unprognostic (2.84e-1)" "unprognostic (3.77e-1)" "unprognostic (7.31e-2)" 0.0 2.4 0.4 0.0 0.4 0.1 0.0 1.8 0.7 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.7 2.2 0.0 0.1 0.0 0.9 0.5 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.1 0.0 0.4 0.1 1.1 17.1 1.0 0.0 0.0 0.0 0.3 0.1 0.2 1.3 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 5.0 1.1 0.4 0.0 0.0 0.3 0.1 0.0 21.7 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.4 0.4 1.8 0.7 0.7 0.7 0.9 0.5 1.1 0.4 1.0 1.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SHOX "GCFX, PHOG, SHOXY, SS" ENSG00000185960 "Short stature homeobox" O15266 X 624344-659411 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 7.6" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 2.0" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "midbrain: 7.6;pons: 7.5" "Immune cell enhanced" "Detected in some" "basophil: 2.9" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 4 "BJ: 18.5;BJ hTERT+: 8.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "midbrain: 2.7;thalamus: 3.8" "HPA035141, HPA060931" Enhanced Nucleoplasm,Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Vesicles "HPA035141: AB_2674489, HPA060931: AB_2684388" "unprognostic (7.51e-3)" "unprognostic (1.99e-1)" "unprognostic (3.08e-2)" "unprognostic (2.23e-1)" "unprognostic (4.00e-1)" "unprognostic (6.82e-2)" "unprognostic (2.45e-2)" "unprognostic (2.34e-1)" "unprognostic (9.24e-2)" "unprognostic (9.95e-2)" "unprognostic (5.67e-6)" "unprognostic (1.99e-1)" "unprognostic (1.71e-1)" "unprognostic (9.14e-2)" "unprognostic (1.38e-1)" 0.7 0.4 0.2 0.3 0.3 0.9 0.2 1.4 0.6 0.0 0.0 0.2 0.6 0.1 0.3 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.1 0.1 0.3 1.2 7.6 0.1 0.3 0.2 0.0 0.1 7.5 0.3 0.2 0.4 0.6 0.0 1.2 0.4 0.4 0.1 0.1 0.7 0.2 0.1 1.4 0.0 0.3 0.0 0.2 0.0 0.0 1.0 0.1 0.1 0.1 0.1 0.2 0.1 3.0 18.5 8.4 2.7 2.9 0.3 0.2 0.2 0.1 0.4 0.7 0.2 0.2 0.0 0.9 0.1 0.1 0.1 1.4 0.1 0.1 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.8 0.1 0.2 0.1 0.1 0.1 0.0 0.3 0.0 0.2 0.2 0.0 0.2 0.2 0.0 0.1 0.1 0.1 0.2 0.5 0.0 0.0 0.2 0.1 0.1 0.1 0.8 0.0 0.2 0.1 0.1 0.0 2.9 0.6 0.6 0.4 0.3 0.4 0.5 0.3 0.3 0.1 0.7 0.4 0.5 1.7 0.7 0.6 0.6 0.3 0.3 0.2 0.3 1.4 0.6 0.2 0.2 1.2 7.6 7.5 0.1 1.4 1.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.2 SHROOM1 "APXL2, KIAA1960" ENSG00000164403 "Shroom family member 1" Q2M3G4 5 132822141-132830659 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 116.9;prostate: 73.9;urinary bladder: 62.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 135.0;Hepatocytes: 79.2;Proximal enterocytes: 65.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RT4: 24.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037690, HPA037691" Uncertain Approved Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA037690: AB_2675613, HPA037691: AB_2675614" "unprognostic (2.50e-1)" "unprognostic (1.06e-1)" "unprognostic (4.52e-2)" "unprognostic (2.66e-1)" "unprognostic (1.45e-2)" "unprognostic (3.47e-1)" "unprognostic (9.26e-2)" "unprognostic (1.33e-2)" "unprognostic (3.74e-1)" "unprognostic (3.24e-1)" "unprognostic (2.46e-2)" "unprognostic (1.01e-2)" "prognostic unfavorable (5.72e-6)" "unprognostic (8.22e-2)" "unprognostic (2.91e-2)" "unprognostic (2.88e-2)" "unprognostic (2.26e-3)" 9.3 2.4 25.2 2.6 32.0 0.2 8.2 28.9 26.9 12.6 10.4 20.5 6.1 11.3 2.1 5.1 8.4 6.7 7.6 20.2 23.6 10.7 116.9 10.5 0.6 42.1 30.9 5.6 16.2 4.9 6.8 11.8 33.3 73.9 11.1 3.4 7.0 15.2 1.7 1.5 16.6 3.9 26.1 2.3 10.9 1.7 31.2 0.6 6.9 1.3 0.5 62.4 9.3 55.7 8.6 5.1 0.9 0.8 1.4 4.0 9.0 9.1 7.7 7.0 7.8 11.2 5.7 1.5 12.5 4.9 3.8 0.8 3.1 5.7 4.3 9.5 11.0 0.3 8.7 10.5 4.1 0.7 3.1 1.7 3.0 4.9 3.0 4.8 4.8 0.1 7.3 8.1 6.1 4.8 0.2 4.0 1.4 6.7 8.1 0.5 0.0 0.8 1.2 24.4 5.7 1.5 8.8 0.7 4.9 4.5 5.2 2.9 4.5 8.1 11.7 1.1 11.5 9.2 6.8 0.1 7.9 0.0 2.5 0.2 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 25.2 32.0 28.9 26.9 20.2 23.6 42.1 30.9 33.3 26.1 31.2 55.7 18.3 25.6 22.3 18.9 1.8 1.3 15.4 2.3 3.4 3.7 9.3 5.5 2.2 30.0 11.3 9.2 10.4 6.8 1.0 135.0 1.9 6.0 0.9 7.1 17.3 18.1 22.8 2.7 3.0 10.7 4.8 6.1 33.6 15.1 8.2 9.0 25.0 79.2 6.6 16.8 1.0 28.6 0.0 8.7 5.5 1.1 4.7 4.6 0.0 23.4 8.1 19.9 3.1 6.6 37.5 7.1 53.6 4.9 3.6 31.6 65.5 3.5 9.1 13.3 26.3 2.8 5.1 7.6 5.1 1.8 2.0 2.9 2.5 1.4 35.5 17.3 SHROOM4 KIAA1202 ENSG00000158352 "Shroom family member 4" Q9ULL8 X 50591642-50814302 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.7" "Group enriched" "Detected in many" 5 "Oligodendrocyte precursor cells: 126.7;Oligodendrocytes: 463.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.7;HUVEC TERT2: 26.7;RH-30: 5.0;RPTEC TERT1: 5.5;TIME: 10.0;WM-115: 5.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA010089, HPA010565" Uncertain Approved "Nucleoplasm,Vesicles,Focal adhesion sites" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Focal adhesion sites" "Nucleoplasm, Vesicles" "HPA010089: , HPA010565: AB_1079961" "unprognostic (2.55e-2)" "unprognostic (1.43e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (8.37e-4)" "unprognostic (1.34e-1)" "unprognostic (1.60e-2)" "unprognostic (4.30e-3)" "unprognostic (4.55e-2)" "unprognostic (2.13e-1)" "unprognostic (2.93e-1)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (7.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.74e-2)" "unprognostic (2.75e-1)" 8.1 1.8 9.8 1.9 20.0 1.2 5.4 17.1 12.4 3.3 0.9 1.8 1.1 3.6 1.6 2.7 2.2 3.0 7.8 8.9 12.6 5.3 0.9 13.3 0.9 23.8 17.6 1.3 0.9 1.9 2.0 9.0 21.8 2.2 1.4 1.3 2.0 1.8 3.6 1.7 1.5 4.1 13.8 1.0 1.3 0.6 17.3 0.6 3.3 5.0 1.0 3.5 2.3 30.7 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.1 0.2 0.0 6.7 0.9 0.0 0.6 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.0 0.0 0.5 0.0 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 5.0 0.0 5.5 2.5 0.1 0.0 0.0 0.8 1.5 3.6 0.1 0.1 10.0 0.0 0.0 0.0 0.7 0.5 0.0 0.0 1.3 0.2 5.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 20.0 17.1 12.4 8.9 12.6 23.8 17.6 21.8 13.8 17.3 30.7 45.0 25.6 18.6 3.3 0.0 3.6 2.0 1.9 2.2 0.3 1.0 1.5 4.2 0.0 2.0 5.5 0.0 0.6 0.2 1.1 3.9 0.7 0.1 2.8 5.4 46.5 3.0 0.0 1.1 0.2 3.0 3.0 0.0 2.9 3.8 2.3 30.7 0.9 0.5 0.0 1.1 2.8 0.0 2.4 2.7 0.6 1.2 0.6 0.0 51.5 0.0 3.6 0.0 126.7 463.4 2.3 1.0 1.2 0.0 1.2 0.3 3.5 2.5 0.6 0.0 2.5 2.6 0.0 1.0 2.0 3.1 0.3 0.6 3.0 3.2 1.6 SIAH2 ENSG00000181788 "Siah E3 ubiquitin protein ligase 2" O43255 3 150741125-150763477 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 226.7;Syncytiotrophoblasts: 389.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061293, CAB069930" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 85: Liver - Metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm Vesicles "CAB069930: AB_1217916, HPA061293: AB_2684470" "prognostic favorable (1.17e-4)" "unprognostic (1.04e-3)" "unprognostic (3.83e-2)" "unprognostic (9.15e-2)" "unprognostic (1.69e-1)" "unprognostic (6.91e-2)" "unprognostic (1.86e-2)" "unprognostic (5.68e-3)" "unprognostic (6.26e-2)" "unprognostic (1.95e-2)" "prognostic unfavorable (8.21e-5)" "unprognostic (1.34e-1)" "unprognostic (1.38e-1)" "unprognostic (2.38e-2)" "unprognostic (5.56e-1)" "unprognostic (1.66e-1)" "unprognostic (4.69e-2)" 15.8 78.6 16.4 20.8 19.0 44.7 17.1 17.4 24.9 48.0 17.3 17.7 13.5 33.4 18.6 46.1 27.2 14.3 16.2 16.9 16.7 12.1 61.2 13.2 35.8 15.8 15.5 24.4 20.9 15.9 11.0 43.1 17.9 19.4 15.4 7.8 16.4 34.7 12.3 30.4 12.9 29.4 15.5 24.4 17.9 8.0 16.5 25.1 8.0 12.8 45.3 23.5 39.6 26.0 54.0 13.4 10.5 20.1 35.4 26.4 41.7 22.9 26.5 27.3 32.4 28.4 24.7 31.3 31.0 24.1 22.8 31.4 28.6 20.7 25.6 24.4 19.5 61.5 16.0 94.7 50.4 34.3 16.0 24.1 47.0 16.3 36.9 21.7 21.5 60.2 15.5 110.8 17.4 66.4 58.7 17.4 33.1 52.3 26.0 44.0 22.7 110.4 17.4 17.9 38.4 19.1 17.4 15.4 39.8 23.8 99.5 50.0 15.0 17.7 15.8 40.1 31.0 130.6 55.9 42.0 17.6 48.6 9.2 8.9 2.2 8.6 1.6 1.2 2.5 2.2 2.8 2.5 2.0 2.2 1.4 1.4 4.7 1.4 1.3 2.6 1.6 0.9 16.4 19.0 17.4 24.9 16.9 16.7 15.8 15.5 17.9 15.5 16.5 26.0 15.9 6.4 4.8 6.8 99.0 146.7 82.3 11.8 153.1 47.0 32.3 22.2 17.8 25.8 11.7 22.0 37.5 192.0 62.6 30.2 13.7 8.5 3.4 56.0 29.2 22.5 38.3 226.7 14.1 6.6 23.4 28.8 44.4 96.5 10.2 18.7 20.7 54.4 32.6 35.3 11.0 39.9 14.2 115.5 102.7 2.1 44.1 70.4 44.4 14.0 22.7 32.7 32.0 5.0 11.5 10.5 17.9 30.9 128.7 56.7 20.7 17.9 16.5 2.8 13.1 11.8 29.9 0.7 10.8 154.1 142.4 389.4 86.1 28.6 34.5 81.8 SIGLEC14 ENSG00000254415 "Sialic acid binding Ig like lectin 14" Q08ET2 19 51642553-51646801 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 28.3;lymphoid tissue: 40.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 18.5;Kupffer cells: 41.5;Macrophages: 13.5;monocytes: 24.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 109.1;intermediate monocyte: 125.1;myeloid DC: 65.4;neutrophil: 200.1;non-classical monocyte: 93.3" "Group enriched" "Detected in many" 7 "dendritic cells: 65.4;granulocytes: 200.1;monocytes: 125.1" "Group enriched" "Detected in some" 11 "HMC-1: 98.7;U-937: 24.7" "HPA014377, HPA014428" Uncertain Uncertain "Vesicles,Plasma membrane" NA NA 24000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane" "HPA014377: AB_2189277, HPA014428: " "unprognostic (3.05e-1)" "unprognostic (1.75e-1)" "unprognostic (6.47e-3)" "unprognostic (1.60e-1)" "unprognostic (3.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (9.77e-3)" "unprognostic (9.28e-2)" "unprognostic (6.73e-2)" "unprognostic (1.02e-1)" "unprognostic (4.28e-3)" "unprognostic (8.38e-2)" "unprognostic (4.17e-2)" "unprognostic (1.34e-1)" "unprognostic (1.89e-1)" 3.4 2.4 1.4 25.2 1.5 28.3 1.0 1.6 3.2 1.8 1.3 1.8 0.7 0.9 0.3 1.1 2.3 2.6 1.3 1.4 2.4 0.7 3.5 7.3 13.3 4.7 3.0 0.4 1.1 0.4 0.5 2.5 3.9 0.9 1.6 0.1 1.1 0.9 0.4 0.3 6.1 2.5 2.7 40.3 1.6 2.4 3.9 1.9 0.6 0.0 14.2 4.1 0.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 1.6 98.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 24.7 0.0 16.6 109.1 1.8 0.3 125.1 0.1 19.3 0.2 0.3 65.4 18.2 0.1 0.1 200.1 0.7 93.3 12.0 0.2 40.3 1.4 1.5 1.6 3.2 1.4 2.4 4.7 3.0 3.9 2.7 3.9 4.1 0.0 0.0 1.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.4 18.5 0.0 0.0 0.0 0.0 41.5 6.0 0.8 0.3 13.5 0.0 1.0 24.1 0.0 2.1 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 SIGLEC7 "CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2" ENSG00000168995 "Sialic acid binding Ig like lectin 7" Q9Y286 19 51142299-51153526 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 31.3;Kupffer cells: 57.4;Macrophages: 33.1;monocytes: 15.5;NK-cells: 69.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 242.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Karpas-707: 55.4;RPMI-8226: 33.7;U-937: 35.0" HPA075513 Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 2600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" Vesicles "HPA075513: " "unprognostic (3.14e-1)" "unprognostic (5.87e-2)" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (3.90e-2)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" "unprognostic (4.95e-2)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.27e-2)" "unprognostic (6.61e-2)" "unprognostic (1.14e-3)" "unprognostic (2.58e-1)" "unprognostic (2.26e-2)" 3.7 2.9 0.9 10.6 1.0 4.6 1.0 1.0 1.9 0.6 1.2 1.9 1.6 0.5 0.4 0.4 1.2 2.6 1.3 0.8 1.3 1.6 7.4 5.0 7.7 2.1 1.5 0.4 0.5 0.7 0.6 6.2 1.9 0.7 2.4 0.2 0.7 0.4 0.2 0.2 2.2 3.8 1.4 19.2 0.9 0.9 2.2 1.5 0.5 0.3 2.4 3.1 0.5 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.4 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.1 33.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.1 0.0 1.2 1.1 0.0 0.2 35.0 0.0 3.2 140.2 242.1 10.6 105.8 18.9 3.8 0.2 4.8 65.5 0.2 0.3 4.4 116.7 96.8 44.0 2.9 0.0 80.9 0.9 1.0 1.0 1.9 0.8 1.3 2.1 1.5 1.9 1.4 2.2 2.4 0.4 0.0 2.2 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 1.8 0.0 0.2 8.3 0.1 0.0 0.0 0.4 0.0 0.2 0.6 0.0 8.8 0.0 0.0 0.2 0.3 0.0 0.0 1.3 0.0 6.1 0.8 31.3 0.0 0.0 0.0 0.0 57.4 3.5 0.0 1.5 33.1 0.0 0.0 15.5 0.0 69.0 0.0 0.0 0.1 0.0 1.2 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 3.5 0.4 0.0 0.0 SIK1 "msk, SNF1LK" ENSG00000142178 "Salt inducible kinase 1" P57059 21 43414483-43427131 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Cell cycle, Differentiation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 88.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 302.0;Basal respiratory cells: 123.5;Langerhans cells: 141.9;Suprabasal keratinocytes: 422.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 35.3;HeLa: 63.1;hTCEpi: 45.4;LHCN-M2: 45.5;U-266/84: 37.7" "Low region specificity" "Detected in all" "CAB023801, HPA038211, HPA078064" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 61: Skin - Cornification" "Cluster 20: HeLa - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" Nucleoplasm Vesicles "CAB023801: , HPA038211: AB_2675894, HPA078064: " "unprognostic (4.06e-2)" "unprognostic (9.38e-2)" "unprognostic (3.31e-3)" "unprognostic (3.00e-1)" "unprognostic (5.02e-2)" "unprognostic (7.97e-3)" "unprognostic (1.51e-1)" "unprognostic (7.30e-3)" "unprognostic (2.35e-3)" "unprognostic (4.97e-2)" "unprognostic (1.89e-2)" "unprognostic (1.30e-1)" "unprognostic (3.89e-1)" "unprognostic (9.94e-3)" "unprognostic (3.88e-2)" "unprognostic (2.89e-1)" "unprognostic (1.82e-1)" 24.5 8.3 0.7 6.2 0.4 10.5 19.5 0.5 1.8 17.5 0.8 7.0 0.4 4.4 0.0 18.5 18.6 15.1 16.0 0.3 1.1 5.1 20.9 12.7 4.3 1.0 1.0 26.9 11.8 5.9 12.5 12.5 0.8 9.2 0.7 8.5 12.1 13.3 13.0 88.0 5.4 5.3 0.0 7.2 12.2 3.0 0.7 11.0 6.2 1.3 4.6 16.9 14.4 0.5 1.2 3.4 4.3 0.1 0.3 1.6 1.7 2.0 0.7 3.5 2.7 5.1 0.1 5.4 1.5 0.4 19.8 23.6 3.5 35.3 2.0 0.3 1.1 1.6 63.1 2.0 4.8 1.7 0.2 2.1 45.4 0.9 10.7 20.7 0.7 0.1 0.2 0.2 45.5 0.3 0.9 3.9 1.9 0.0 3.4 0.1 0.8 5.7 4.0 13.3 0.1 0.0 24.2 4.0 0.8 0.7 2.3 0.6 8.1 0.9 4.2 0.4 0.1 9.5 37.7 1.0 10.0 4.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.4 0.5 1.8 0.3 1.1 1.0 1.0 0.8 0.0 0.7 0.5 23.7 28.9 77.3 0.0 18.4 302.0 0.8 123.5 26.7 0.3 8.6 6.3 11.7 7.2 68.4 12.9 0.0 0.8 13.4 16.4 0.0 3.2 0.0 23.2 4.8 18.4 27.6 0.0 0.0 2.1 1.3 11.1 15.3 29.1 19.6 2.3 4.2 7.7 1.7 0.0 0.0 16.5 85.5 3.8 141.9 0.1 0.0 10.1 96.0 0.0 1.6 1.3 0.0 0.0 0.0 7.3 24.3 0.0 36.3 0.5 23.8 0.2 50.7 0.2 0.0 2.4 27.4 0.1 0.4 35.1 422.7 2.5 16.4 0.8 20.3 1.2 SIK1B ENSG00000275993 "Salt inducible kinase 1B (putative)" A0A0B4J2F2 21 6111131-6123778 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 243.9" "Cell type enhanced" "Detected in some" "Adipocytes: 11.9;Alveolar cells type 1: 25.6;Alveolar cells type 2: 27.2;Endometrial ciliated cells: 17.1;Glandular and luminal cells: 30.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.8" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HeLa: 95.3;hTERT-RPE1: 117.7;Karpas-707: 120.6;LHCN-M2: 83.0;SiHa: 87.2" "HPA038211, HPA078064" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 44: Endometrium - Transcription" Nucleoplasm Vesicles "HPA038211: AB_2675894, HPA078064: " "unprognostic (2.09e-2)" "unprognostic (1.01e-1)" "unprognostic (2.57e-2)" "unprognostic (8.85e-2)" "unprognostic (3.32e-2)" "unprognostic (2.44e-1)" "unprognostic (6.58e-3)" "unprognostic (2.62e-2)" "unprognostic (6.56e-2)" "unprognostic (3.15e-2)" "unprognostic (5.52e-3)" "unprognostic (1.01e-2)" "unprognostic (9.09e-2)" "unprognostic (2.88e-2)" "unprognostic (2.41e-1)" "unprognostic (2.69e-3)" "unprognostic (7.41e-2)" 67.6 52.0 6.5 16.1 5.6 42.4 53.5 5.3 12.3 21.8 7.4 22.2 7.6 16.2 0.4 32.0 31.0 30.4 49.9 6.1 11.2 21.8 71.2 38.1 9.8 10.7 8.0 93.5 47.0 8.0 39.5 14.2 8.3 33.5 12.3 20.9 41.5 41.6 40.1 243.9 17.4 10.5 6.2 18.0 37.5 7.3 7.1 8.2 17.9 4.3 4.7 44.3 46.7 5.7 9.5 47.5 3.5 3.0 0.7 0.4 8.3 1.1 0.6 1.7 1.0 53.3 7.0 3.2 1.4 0.2 7.1 0.8 5.5 0.0 0.6 8.9 1.7 7.4 95.3 10.3 3.1 1.2 0.7 1.2 39.6 4.8 26.5 117.7 2.0 1.5 3.0 120.6 83.0 4.7 0.9 2.3 4.9 8.8 5.1 2.0 21.1 14.3 4.6 16.4 4.4 2.1 87.2 5.5 5.0 2.3 0.9 4.1 2.3 1.4 4.4 2.0 19.9 15.9 37.7 1.6 12.6 3.0 5.6 0.0 0.0 0.0 0.0 0.2 0.1 0.5 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.1 0.6 1.8 0.0 0.0 6.5 5.6 5.3 12.3 6.1 11.2 10.7 8.0 8.3 6.2 7.1 5.7 11.9 25.6 27.2 0.0 2.6 0.0 0.0 0.0 0.0 0.0 4.0 2.7 0.0 0.0 3.7 1.8 0.0 0.7 4.1 0.0 0.0 0.5 0.0 17.1 3.4 1.4 0.0 0.0 0.0 0.2 0.9 1.5 0.0 30.0 6.3 1.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 3.1 0.0 0.0 0.2 8.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.5 2.4 0.0 0.0 0.0 SIK2 "DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2" ENSG00000170145 "Salt inducible kinase 2" Q9H0K1 11 111602449-111730855 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 113.3;Excitatory neurons: 217.6;Inhibitory neurons: 132.4;Oligodendrocytes: 191.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "ASC diff: 50.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016026, HPA071049" Approved Approved "Nucleoplasm,Nuclear speckles,Vesicles,Intermediate filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" "Nuclear speckles, Intermediate filaments, Cytosol" "HPA016026: AB_1857321, HPA071049: " "unprognostic (2.35e-1)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (1.10e-2)" "unprognostic (1.59e-2)" "unprognostic (4.81e-2)" "prognostic favorable (4.93e-4)" "unprognostic (6.41e-2)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (3.72e-3)" "unprognostic (9.27e-2)" "prognostic favorable (1.17e-9)" "unprognostic (1.23e-1)" "unprognostic (2.79e-1)" "unprognostic (2.82e-3)" "unprognostic (2.13e-2)" 29.7 9.3 9.2 5.3 12.4 3.1 20.7 7.9 11.1 7.6 11.0 7.9 5.9 7.3 5.0 5.9 8.1 10.0 12.3 9.5 14.7 11.4 22.7 11.7 4.4 11.9 11.9 14.9 31.8 21.3 16.6 5.8 10.6 6.7 6.2 30.7 13.8 6.2 33.1 8.9 7.5 5.9 5.5 4.6 17.6 3.0 9.3 5.4 8.7 23.2 4.3 7.7 6.1 11.6 9.2 6.0 10.3 11.1 50.3 14.8 6.1 7.9 11.2 5.9 6.7 20.5 9.6 7.2 10.7 9.2 6.9 12.7 8.2 5.9 7.6 5.4 3.4 7.9 5.2 10.1 10.9 7.7 4.9 14.5 8.6 8.7 11.1 11.7 7.1 7.1 7.4 10.3 9.4 4.3 8.0 7.0 3.5 7.6 5.9 10.6 11.0 8.7 13.1 8.2 4.8 11.3 11.6 4.7 4.5 9.4 11.5 6.2 9.9 12.9 7.7 8.3 10.9 2.9 2.4 14.8 4.2 10.6 8.8 0.3 0.7 0.6 0.7 0.7 0.3 0.4 0.5 0.5 0.6 0.4 0.2 0.4 0.3 0.5 0.6 0.3 0.5 0.5 9.2 12.4 7.9 11.1 9.5 14.7 11.9 11.9 10.6 5.5 9.3 11.6 22.1 19.2 24.8 113.3 14.1 14.7 6.2 5.2 18.2 15.7 10.5 9.9 21.3 27.1 10.0 16.5 66.7 4.4 11.4 15.6 5.9 10.4 16.5 27.7 14.9 18.8 18.0 12.4 217.6 7.9 4.6 20.1 27.5 45.3 9.5 24.3 9.3 38.7 5.4 32.0 132.4 11.3 4.1 12.4 16.9 14.1 11.5 13.3 19.6 73.1 6.0 14.5 4.1 86.0 191.9 8.4 10.3 14.7 8.9 6.9 8.3 23.1 13.4 60.9 0.0 19.1 19.0 3.9 6.4 10.3 11.9 5.2 12.6 5.0 11.5 7.1 SIKE1 "FLJ21168, SIKE" ENSG00000052723 "Suppressor of IKBKE 1" Q9BRV8 1 114769479-114780685 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024177, HPA025726" Supported Approved "Vesicles,Focal adhesion sites" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" "Focal adhesion sites" Vesicles "HPA024177: AB_1848798, HPA025726: AB_1848800" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" "unprognostic (3.53e-2)" "unprognostic (4.52e-3)" "unprognostic (4.10e-1)" "unprognostic (6.04e-2)" "unprognostic (3.37e-3)" "unprognostic (2.11e-1)" "unprognostic (1.72e-2)" "unprognostic (2.52e-2)" "unprognostic (1.94e-2)" "unprognostic (7.91e-2)" "unprognostic (2.38e-2)" "unprognostic (3.86e-2)" "unprognostic (9.06e-2)" "unprognostic (2.95e-3)" "unprognostic (1.05e-1)" 8.8 6.9 5.9 9.7 6.0 9.8 9.6 8.5 6.7 9.1 5.7 8.6 9.8 9.4 7.6 7.7 6.0 6.9 7.3 4.9 7.7 10.8 12.2 6.8 12.1 7.0 6.8 8.6 6.8 9.7 4.9 9.6 7.0 7.6 9.4 8.0 7.3 7.5 6.7 13.4 8.5 9.2 6.4 9.5 8.4 5.6 8.2 13.6 10.1 7.4 12.0 7.2 5.6 7.1 16.3 4.4 22.9 21.2 27.6 21.4 22.0 13.9 12.4 18.9 25.3 12.2 9.1 30.6 12.5 11.8 8.0 15.7 24.3 16.7 27.0 19.4 13.3 16.4 13.9 15.6 26.3 18.8 12.9 21.0 19.6 14.1 22.4 13.6 17.5 26.2 25.2 17.7 15.7 62.7 37.1 19.9 52.1 10.5 12.3 21.2 43.7 15.3 16.0 13.5 15.7 18.5 20.0 23.2 25.5 20.8 12.6 72.0 13.9 15.6 19.0 26.8 19.0 16.4 14.1 29.1 23.7 31.1 34.0 6.0 1.7 2.0 2.2 2.3 2.8 2.0 2.2 2.2 2.2 2.1 2.6 2.8 1.2 2.6 2.4 2.7 1.7 1.4 5.9 6.0 8.5 6.7 4.9 7.7 7.0 6.8 7.0 6.4 8.2 7.1 29.2 25.6 14.8 13.1 32.7 31.9 26.7 40.0 30.1 10.7 22.7 23.2 41.0 20.0 30.2 31.3 10.4 29.7 43.9 30.3 50.9 27.1 34.8 20.1 34.9 26.3 18.6 29.9 16.2 25.7 33.6 27.9 18.8 26.8 19.7 77.1 27.1 40.0 27.7 8.4 19.7 21.4 48.8 19.7 26.6 58.1 28.3 24.8 23.2 4.7 25.4 15.8 32.0 10.1 16.6 31.1 18.3 19.9 37.7 30.5 25.7 62.8 21.3 16.1 19.7 26.5 28.8 35.5 39.6 33.0 36.4 36.0 37.4 48.3 21.2 23.6 SIRPB1 "CD172b, SIRP-BETA-1" ENSG00000101307 "Signal regulatory protein beta 1" "O00241, Q5TFQ8" 20 1561385-1620061 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 52.2;lung: 19.4;lymphoid tissue: 28.6" "Cell type enhanced" "Detected in some" "dendritic cells: 10.9;Hofbauer cells: 14.7;Kupffer cells: 29.4;Macrophages: 30.9;monocytes: 26.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "neutrophil: 1594.8" "Group enriched" "Detected in all" 6 "granulocytes: 1594.8;monocytes: 502.2" "Group enriched" "Detected in some" 4 "HMC-1: 54.0;NB-4: 76.2;THP-1: 58.9" HPA047463 Uncertain Uncertain Vesicles,Centrosome NA NA 44000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles Centrosome "HPA047463: AB_2680057" "unprognostic (1.88e-2)" "unprognostic (6.19e-2)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (5.38e-2)" "unprognostic (1.60e-1)" "unprognostic (4.40e-2)" "unprognostic (7.18e-2)" "unprognostic (4.11e-3)" "unprognostic (9.12e-2)" "unprognostic (6.31e-2)" "unprognostic (4.57e-2)" "unprognostic (2.65e-3)" "unprognostic (5.76e-2)" "unprognostic (2.39e-3)" "unprognostic (5.00e-3)" "unprognostic (1.19e-2)" 5.4 1.6 1.3 28.6 1.3 52.2 1.9 1.2 4.2 1.2 0.1 2.1 1.5 0.8 0.8 1.3 2.2 11.2 1.6 1.4 0.8 1.2 3.1 19.4 11.0 0.7 0.8 0.7 1.3 0.3 0.6 2.8 1.3 0.8 1.8 1.2 1.7 0.9 0.8 0.8 2.8 3.2 0.9 24.5 1.5 0.6 2.1 4.5 0.9 1.5 4.3 8.1 0.8 1.9 0.2 0.0 0.2 0.1 0.3 0.5 0.2 0.4 0.1 0.2 0.0 0.2 0.1 0.1 0.8 0.4 7.1 0.3 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.2 14.9 54.0 0.1 0.2 0.3 0.0 8.0 0.5 1.1 0.0 0.2 0.4 0.1 0.0 76.2 0.2 0.0 3.3 0.2 0.0 0.1 10.8 0.3 0.1 0.2 0.2 0.0 0.5 0.0 0.0 58.9 1.6 0.7 0.1 0.4 0.3 0.1 0.1 0.1 1.1 13.4 0.2 6.1 502.2 868.9 7.3 419.7 10.3 2.8 6.5 5.7 175.2 3.4 8.8 5.5 1594.8 8.2 357.6 165.7 11.8 287.0 1.3 1.3 1.2 4.2 1.4 0.8 0.7 0.8 1.3 0.9 2.1 1.9 0.6 3.2 5.2 0.3 1.2 0.0 0.1 0.2 0.6 0.2 0.1 0.0 0.5 0.0 1.6 0.0 0.0 0.2 10.9 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 1.3 0.3 0.0 0.1 0.7 0.0 0.2 7.0 0.0 1.8 0.2 14.7 0.0 0.1 0.0 0.0 29.4 0.0 0.0 0.0 30.9 0.0 0.0 26.7 0.1 0.0 0.5 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 1.8 0.0 0.0 0.0 SIRT6 ENSG00000077463 "Sirtuin 6" Q8N6T7 19 4174109-4182566 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Distal enterocytes: 199.2;Paneth cells: 129.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049729, HPA071776" Supported Supported Nucleoplasm,Vesicles No No "Cluster 52: Eosinophils - Transcription" "Cluster 45: Intestine - Brush border" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA049729: AB_2680865, HPA071776: AB_2686445" "unprognostic (4.58e-1)" "unprognostic (3.41e-3)" "unprognostic (1.36e-1)" "prognostic favorable (2.85e-4)" "unprognostic (2.28e-1)" "unprognostic (4.14e-2)" "unprognostic (2.93e-3)" "unprognostic (8.32e-2)" "unprognostic (1.86e-1)" "unprognostic (6.13e-2)" "unprognostic (7.27e-3)" "unprognostic (4.42e-2)" "unprognostic (5.84e-2)" "prognostic favorable (9.13e-4)" "unprognostic (5.17e-2)" "unprognostic (1.63e-1)" "prognostic favorable (2.58e-4)" 8.2 12.0 10.4 7.8 10.6 10.4 8.6 10.3 15.1 10.5 8.7 23.6 10.0 10.6 2.4 12.3 9.2 3.5 10.0 10.7 10.2 13.7 11.0 8.9 7.1 11.2 10.3 7.5 14.1 5.2 13.3 4.3 10.5 12.7 7.5 1.9 9.3 5.0 8.0 11.8 14.2 2.6 9.8 15.3 9.8 6.0 12.1 4.9 10.1 2.7 3.9 9.9 9.7 10.6 25.7 16.8 8.3 10.4 6.5 6.2 12.9 12.0 8.9 10.1 8.8 11.2 9.5 16.0 12.9 8.1 9.1 15.9 4.6 12.9 1.6 30.8 10.0 6.8 9.7 10.3 14.3 17.4 25.2 7.9 10.4 10.3 6.4 7.7 8.7 15.0 15.2 35.3 5.4 19.2 23.9 18.3 14.5 9.3 15.2 18.9 7.7 18.8 9.7 11.4 11.0 18.1 11.0 10.2 24.1 3.2 10.2 23.0 12.2 10.4 10.5 36.9 17.4 45.6 25.7 18.4 20.8 28.1 12.7 5.3 13.1 12.2 10.8 16.3 6.4 9.6 7.5 8.7 14.3 10.1 6.4 6.1 11.8 5.6 13.5 11.9 12.6 8.5 10.4 10.6 10.3 15.1 10.7 10.2 11.2 10.3 10.5 9.8 12.1 10.6 9.2 12.8 7.3 5.9 13.8 10.3 10.3 32.3 9.6 12.6 6.6 6.3 3.2 7.2 18.4 5.5 18.8 24.1 7.1 199.2 13.7 32.2 1.9 6.2 7.9 11.8 26.4 9.5 8.9 26.7 24.2 9.3 19.9 9.2 5.7 5.6 13.6 6.8 24.0 13.5 10.4 29.1 18.3 11.7 10.1 2.6 11.5 15.0 5.4 1.9 27.0 15.2 14.4 3.5 6.3 32.5 129.7 8.2 10.3 9.7 28.2 14.3 11.0 13.8 0.0 7.2 11.3 7.4 9.6 13.3 12.6 25.6 10.6 7.9 30.9 11.9 SLA2 "C20orf156, FLJ21992, SLAP-2" ENSG00000101082 "Src like adaptor 2" Q9H6Q3 20 36612318-36646196 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.5;lymphoid tissue: 18.3" "Cell type enhanced" "Detected in some" "dendritic cells: 97.0;Macrophages: 21.8;NK-cells: 44.3;Plasma cells: 25.8;T-cells: 59.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 6 "gdT-cell: 28.8;MAIT T-cell: 24.1;memory CD4 T-cell: 23.8;memory CD8 T-cell: 27.1;naive CD4 T-cell: 21.8;naive CD8 T-cell: 30.5;NK-cell: 39.2;plasmacytoid DC: 48.5;T-reg: 33.4" "Group enriched" "Detected in many" 8 "dendritic cells: 48.5;NK-cells: 39.2;T-cells: 33.4" "Group enriched" "Detected in some" 7 "HEL: 91.2;JURKAT: 51.8" "Not detected" "Not detected" "HPA053746, HPA058217" Approved "Nucleoplasm,Golgi apparatus,Vesicles" No NA "Cluster 48: NK-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 36: HEL - Hemostasis" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA053746: AB_2682246, HPA058217: AB_2683641" "unprognostic (4.16e-3)" "prognostic favorable (7.36e-4)" "unprognostic (4.52e-4)" "unprognostic (2.30e-6)" "unprognostic (3.37e-2)" "unprognostic (3.79e-3)" "unprognostic (2.15e-3)" "unprognostic (1.13e-2)" "unprognostic (1.32e-2)" "unprognostic (2.84e-2)" "unprognostic (3.22e-3)" "unprognostic (1.23e-1)" "prognostic unfavorable (6.77e-8)" "unprognostic (8.48e-2)" "unprognostic (1.73e-1)" "unprognostic (1.98e-2)" "unprognostic (6.45e-3)" 1.3 0.6 0.4 5.7 0.6 12.5 0.8 1.6 0.7 0.8 0.3 1.7 2.7 1.0 0.5 0.7 0.9 2.4 0.7 0.4 0.2 0.5 1.5 4.1 10.4 0.7 0.4 0.4 0.4 0.1 0.4 0.6 0.8 0.7 1.7 0.5 1.4 0.5 0.6 0.7 3.1 0.5 0.3 8.0 2.6 0.5 0.6 18.3 0.7 0.2 9.0 2.2 0.6 1.1 0.0 0.2 0.2 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 91.2 0.6 3.4 0.0 2.5 0.3 0.1 0.1 0.0 0.0 0.0 0.1 51.8 0.1 0.2 0.0 0.2 10.9 7.6 0.1 0.0 0.0 0.5 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.2 2.3 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.6 0.1 7.6 0.1 3.0 0.4 3.8 28.8 0.7 24.1 0.4 23.8 27.1 0.4 0.3 21.8 30.5 4.8 39.2 0.1 48.5 33.4 26.5 0.4 0.6 1.6 0.7 0.4 0.2 0.7 0.4 0.8 0.3 0.6 1.1 0.6 0.0 3.9 0.0 1.6 0.4 0.1 0.0 0.0 0.3 0.5 0.3 0.3 0.0 0.7 0.0 0.0 0.1 97.0 0.6 0.0 0.2 1.1 0.4 0.4 0.4 0.0 8.2 2.2 0.0 0.2 0.5 4.1 0.6 1.3 0.0 0.7 0.1 0.2 0.0 1.7 0.0 0.0 1.6 0.4 0.0 0.3 21.8 0.0 1.9 1.2 0.4 44.3 1.5 1.4 0.3 0.1 0.0 25.8 0.1 0.0 0.1 0.0 0.9 0.0 0.3 0.4 0.0 0.2 0.2 0.1 0.1 59.2 0.0 0.2 0.3 SLAMF7 "19A, CD319, CRACC, CS1" ENSG00000026751 "SLAM family member 7" Q9NQ25 1 160739057-160754821 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.6;lymphoid tissue: 62.0;stomach 1: 34.2" "Cell type enhanced" "Detected in many" "dendritic cells: 58.3;monocytes: 120.2;NK-cells: 76.2;Plasma cells: 240.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 5 "U-266/70: 283.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015445, HPA055945, HPA061654" Enhanced Approved Vesicles NA NA 1200000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 14: B-cells - Humoral immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "CAB015445: AB_1121905, HPA055945: AB_2682980, HPA061654: AB_2684576" "unprognostic (5.82e-3)" "unprognostic (1.81e-2)" "unprognostic (1.84e-3)" "unprognostic (2.12e-3)" "unprognostic (2.75e-1)" "unprognostic (1.07e-2)" "unprognostic (7.87e-2)" "unprognostic (7.19e-2)" "unprognostic (2.46e-2)" "prognostic favorable (3.93e-4)" "unprognostic (1.08e-1)" "unprognostic (8.13e-2)" "prognostic unfavorable (8.57e-5)" "unprognostic (1.35e-1)" "unprognostic (3.91e-2)" "unprognostic (1.02e-1)" "unprognostic (1.50e-2)" 2.2 3.0 0.2 34.6 0.2 9.7 11.3 0.2 0.6 3.4 0.7 32.6 32.2 2.2 1.7 5.9 2.1 8.7 1.6 0.2 0.2 1.4 7.9 14.5 50.8 0.4 0.2 2.3 1.1 0.4 0.3 1.4 0.6 2.6 28.6 0.0 13.7 2.4 0.5 1.7 25.5 3.7 0.4 42.3 34.2 1.4 0.3 14.7 1.6 0.2 62.0 22.2 2.1 0.5 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 1.0 0.8 0.0 2.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 10.2 0.0 7.6 0.0 2.5 0.7 0.0 0.2 0.0 7.2 0.0 0.0 0.1 0.0 0.2 1.4 0.0 0.1 0.1 10.0 0.0 0.8 0.0 0.1 0.0 0.0 59.5 0.0 0.0 0.1 0.2 0.0 3.8 0.0 0.2 283.7 26.4 0.2 7.9 0.2 0.0 0.2 5.1 1.4 100.5 34.8 77.3 11.0 10.2 69.0 23.6 2.3 3.0 40.1 3.5 55.5 53.1 89.7 0.0 33.6 0.2 0.2 0.2 0.6 0.2 0.2 0.4 0.2 0.6 0.4 0.3 0.5 0.4 9.6 6.0 0.0 37.4 0.8 1.6 0.3 0.0 0.0 0.2 0.6 1.3 1.5 1.0 0.0 0.0 0.1 58.3 0.2 0.0 0.7 0.0 0.2 0.2 1.4 0.0 3.6 0.0 2.7 0.1 1.7 1.5 0.4 8.8 0.0 0.7 0.6 8.4 0.0 0.0 0.0 0.0 7.3 9.2 0.1 0.0 28.2 19.6 1.0 120.2 0.0 76.2 0.0 0.0 8.6 0.0 0.0 240.9 2.5 0.0 0.2 1.7 0.0 0.0 4.8 1.3 0.0 0.1 0.7 0.4 0.3 37.1 0.0 0.4 3.7 SLC12A1 NKCC2 ENSG00000074803 "Solute carrier family 12 member 1" Q13621 15 48178438-48304078 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Symport, Transport" "Bartter syndrome, Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 878 "kidney: 705.6" "Cell type enriched" "Detected in some" 5 "Distal tubular cells: 209.4" "Cancer enriched" "Detected in single" 4 "renal cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 26 "RPTEC TERT1: 25.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA014967, HPA018107" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 39: Non-specific - Basic cellular processes" Vesicles Nucleoplasm "HPA014967: AB_1854503, HPA018107: AB_1854504" "unprognostic (3.52e-2)" "unprognostic (1.30e-2)" "unprognostic (9.65e-2)" "unprognostic (1.74e-2)" "unprognostic (7.77e-2)" "unprognostic (1.04e-1)" "unprognostic (8.72e-2)" "unprognostic (2.06e-1)" "unprognostic (9.85e-3)" "unprognostic (2.81e-4)" "unprognostic (9.75e-2)" "unprognostic (2.61e-1)" "unprognostic (5.47e-2)" "unprognostic (2.03e-1)" "unprognostic (5.20e-4)" "unprognostic (8.52e-2)" 0.1 0.0 0.3 0.1 0.2 0.2 0.1 0.5 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 705.6 0.4 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.5 0.4 0.2 0.6 0.5 0.6 0.4 0.2 0.3 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.7 0.0 0.0 38.6 0.0 0.0 0.0 0.0 209.4 0.0 13.5 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 13.2 0.3 0.1 0.0 1.0 0.0 0.0 0.0 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.2 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC12A2 "BSC, BSC2, NKCC1, PPP1R141" ENSG00000064651 "Solute carrier family 12 member 2" P55011 5 128083766-128189677 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 75.6" "Cell type enhanced" "Detected in all" "Intestinal goblet cells: 480.6;Oligodendrocytes: 566.6;Undifferentiated cells: 370.0" "Cancer enhanced" "Detected in all" "colorectal cancer: 54.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "OE19: 153.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020130, HPA063697" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Vesicles "Plasma membrane" "HPA020130: AB_1854502, HPA063697: AB_2685094" "unprognostic (4.61e-2)" "unprognostic (2.63e-1)" "unprognostic (4.20e-3)" "prognostic favorable (8.60e-4)" "unprognostic (3.99e-1)" "unprognostic (5.65e-3)" "unprognostic (1.44e-3)" "unprognostic (1.81e-1)" "unprognostic (3.30e-1)" "unprognostic (2.95e-2)" "unprognostic (7.22e-2)" "unprognostic (1.39e-1)" "prognostic favorable (7.09e-4)" "unprognostic (1.63e-1)" "unprognostic (2.30e-1)" "unprognostic (3.79e-1)" "unprognostic (3.88e-3)" 8.4 17.5 15.0 10.8 48.4 4.4 43.9 46.3 23.2 7.2 40.4 48.5 41.7 8.4 2.4 4.6 6.0 39.4 6.1 13.5 31.1 6.6 4.2 10.3 5.6 40.8 43.1 5.4 6.1 14.7 5.5 4.9 38.6 23.5 58.9 16.8 75.6 2.6 15.4 28.4 49.1 10.2 27.1 4.5 61.8 8.0 32.4 4.1 8.6 8.3 6.0 7.3 3.5 64.8 13.5 65.3 65.8 25.6 16.1 10.4 13.6 12.2 9.1 8.6 8.9 26.4 20.9 19.9 16.1 10.6 7.8 39.5 12.7 14.0 13.2 20.0 15.8 5.7 11.4 3.8 4.9 7.3 9.5 11.1 5.0 19.1 11.2 6.4 14.2 8.5 9.4 13.2 13.4 14.2 13.0 6.1 7.7 153.6 21.1 7.1 18.5 8.2 10.0 45.0 11.5 7.3 24.6 10.6 9.9 7.0 5.9 3.7 24.1 21.2 14.2 16.3 15.7 11.0 10.7 21.6 11.2 4.2 17.6 0.3 0.4 0.2 1.1 0.7 1.9 1.7 1.0 1.4 0.6 2.1 1.1 1.6 0.2 2.4 0.5 6.4 1.1 0.3 15.0 48.4 46.3 23.2 13.5 31.1 40.8 43.1 38.6 27.1 32.4 64.8 38.3 16.0 46.2 23.8 20.5 22.9 20.1 44.9 10.8 76.6 186.9 86.7 18.0 137.2 52.1 33.1 127.2 1.4 34.4 48.2 1.9 68.6 55.8 33.1 43.1 44.2 74.4 2.5 160.6 48.2 2.7 21.3 199.3 38.4 18.4 28.8 12.8 8.8 4.2 80.8 73.2 480.6 57.0 8.6 12.0 95.3 85.4 11.4 204.5 105.9 2.5 22.6 11.3 55.3 566.6 50.1 60.6 29.0 20.2 131.6 38.8 10.6 19.6 86.4 72.3 33.9 64.3 29.1 27.1 14.9 30.0 1.4 21.1 14.1 370.0 21.5 SLC12A6 "ACCPN, KCC3" ENSG00000140199 "Solute carrier family 12 member 6" Q9UHW9 15 34229784-34338060 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" Neuropathy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 15.2;neutrophil: 23.4" "Lineage enriched" "Detected in many" 7 "granulocytes: 23.4" "Cell line enhanced" "Detected in many" "HaCaT: 44.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034563 Uncertain Approved Vesicles,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 34: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 57: B-cells - Immune response" "Vesicles, Cytosol" "HPA034563: AB_10603887" "unprognostic (3.53e-1)" "unprognostic (4.82e-2)" "unprognostic (4.26e-2)" "unprognostic (3.60e-1)" "unprognostic (3.55e-2)" "unprognostic (3.41e-2)" "unprognostic (1.36e-1)" "unprognostic (2.88e-1)" "unprognostic (2.07e-1)" "unprognostic (1.68e-1)" "unprognostic (6.58e-2)" "unprognostic (1.83e-1)" "prognostic favorable (3.33e-6)" "unprognostic (2.39e-1)" "unprognostic (1.61e-1)" "unprognostic (3.87e-2)" "unprognostic (1.41e-1)" 6.4 4.0 5.9 11.5 7.4 26.8 5.5 7.2 7.9 11.9 2.5 5.5 7.3 5.2 7.0 18.8 4.6 5.2 7.3 6.5 7.3 15.9 3.9 9.1 10.1 8.9 7.3 4.2 3.5 3.1 5.6 4.3 9.3 3.5 6.1 31.1 6.4 3.8 10.6 7.6 9.1 4.9 6.6 12.9 6.7 25.9 7.7 15.5 9.0 10.9 11.6 8.3 17.6 8.4 4.4 5.2 3.1 4.7 10.0 11.4 2.4 5.9 15.1 4.9 7.1 3.1 7.2 3.1 5.9 7.2 4.3 44.0 7.9 5.3 5.8 1.2 5.1 24.6 14.0 7.0 6.4 14.5 24.6 6.9 9.1 14.1 29.1 10.9 14.9 6.8 5.4 6.8 6.7 1.6 1.6 11.0 2.4 3.8 5.7 7.1 5.5 3.3 5.5 11.2 7.2 5.0 7.1 0.2 1.5 7.1 2.8 4.8 9.4 5.9 4.2 21.0 1.4 6.4 6.8 1.9 6.6 10.5 2.2 15.2 1.4 2.6 0.6 1.8 0.4 1.4 0.9 0.9 0.9 2.4 1.6 1.4 23.4 0.7 0.8 1.0 3.2 1.0 5.9 7.4 7.2 7.9 6.5 7.3 8.9 7.3 9.3 6.6 7.7 8.4 16.4 22.4 21.0 30.0 32.0 1.1 4.5 1.5 7.4 15.3 5.2 4.3 8.7 5.7 4.2 5.5 85.5 3.2 11.5 8.6 0.0 5.6 15.6 9.8 7.4 17.7 6.7 35.9 47.7 4.7 1.6 7.0 17.9 22.4 5.1 8.4 16.1 7.5 13.2 8.4 52.0 7.0 2.0 37.1 3.8 8.3 8.1 25.6 0.0 50.6 34.5 8.7 15.5 40.7 58.4 13.1 9.7 8.6 29.9 6.5 18.3 16.4 4.2 56.6 19.7 7.0 4.0 39.9 21.2 14.8 0.9 1.1 18.0 4.1 7.4 43.6 SLC15A3 "hPTR3, PHT2" ENSG00000110446 "Solute carrier family 15 member 3" Q8IY34 11 60937060-60952653 "Metabolic proteins, Predicted membrane proteins, Transporters" "Immunity, Innate immunity, Peptide transport, Protein transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 90.6;Kupffer cells: 59.3;Macrophages: 65.5;monocytes: 70.9;Muller glia cells: 211.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 9.0;intermediate monocyte: 12.8;memory B-cell: 4.9;myeloid DC: 6.5;neutrophil: 13.4;non-classical monocyte: 6.4;plasmacytoid DC: 10.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 23.4;BJ hTERT+ SV40 Large T+: 58.0;BJ hTERT+ SV40 Large T+ RasG12V: 74.0;HHSteC: 34.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047880, HPA057642" Approved Supported Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 5: Muller glia cells - Visual perception" Vesicles "HPA047880: AB_10959455, HPA057642: AB_2683487" "unprognostic (5.61e-2)" "prognostic favorable (4.07e-5)" "unprognostic (8.79e-2)" "unprognostic (1.67e-2)" "unprognostic (8.48e-2)" "unprognostic (9.33e-3)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-1)" "unprognostic (1.60e-1)" "unprognostic (1.46e-1)" "unprognostic (9.78e-3)" "unprognostic (6.47e-2)" "unprognostic (4.42e-2)" "unprognostic (1.34e-1)" "unprognostic (1.02e-1)" 27.5 12.8 11.6 30.7 10.3 35.3 18.2 10.7 15.1 19.7 13.0 34.9 12.0 13.9 3.9 9.3 18.2 19.1 27.1 9.7 13.1 14.9 15.1 52.2 40.1 14.5 10.9 29.2 6.5 4.4 8.4 27.5 13.8 16.7 9.4 17.5 10.0 8.5 6.4 7.9 28.7 15.1 13.5 63.9 18.5 5.5 14.3 12.9 10.5 10.1 15.7 15.6 17.6 15.5 4.3 0.0 2.2 0.0 12.6 9.9 23.4 1.2 21.8 58.0 74.0 0.1 1.9 9.7 0.3 8.8 14.2 1.7 0.0 0.7 3.4 9.4 0.0 0.1 0.1 0.6 34.9 0.0 0.9 6.6 0.0 15.3 0.0 0.1 2.8 0.0 0.0 0.5 3.6 0.5 0.0 1.8 9.8 0.0 0.1 3.9 0.0 3.3 0.0 1.3 0.0 0.1 2.8 9.6 0.4 0.4 4.2 5.7 0.3 0.3 1.2 1.0 0.1 0.0 0.0 3.8 3.9 0.0 13.7 0.0 9.0 1.2 0.1 12.8 0.0 4.9 0.0 0.0 6.5 1.9 0.9 0.9 13.4 0.0 6.4 10.7 0.0 2.4 11.6 10.3 10.7 15.1 9.7 13.1 14.5 10.9 13.8 13.5 14.3 15.5 19.3 9.6 13.2 0.0 7.7 1.7 0.2 4.5 2.2 1.6 0.7 1.4 2.5 1.5 3.7 0.0 0.0 3.6 9.6 1.1 0.0 0.3 7.9 0.1 2.0 12.6 0.0 0.4 0.1 2.2 15.1 5.6 1.1 0.3 15.2 3.7 20.3 3.1 90.6 5.0 0.0 1.2 2.0 59.3 35.5 3.8 8.1 65.5 1.8 4.7 70.9 211.7 1.0 0.0 0.1 2.2 2.8 4.9 2.0 0.1 0.3 0.1 3.1 5.5 13.1 3.1 3.0 4.2 0.7 0.6 1.4 2.6 1.9 4.5 1.1 0.3 SLC16A10 "MCT10, TAT1" ENSG00000112394 "Solute carrier family 16 member 10" Q8TF71 6 111087503-111231194 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 53.7;skeletal muscle: 41.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 32.8;Excitatory neurons: 33.9;Inhibitory neurons: 47.8;Macrophages: 33.8;Melanocytes: 44.4" "Cancer enriched" "Detected in many" 6 "testis cancer: 4.5" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.7;T-reg: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HAP1: 49.4;HEK 293: 20.2;RPMI-8226: 37.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016860 Approved Supported "Vesicles,Cell Junctions" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 41: Macrophages - Immune response" "Vesicles, Cell Junctions" "HPA016860: AB_2189211" "unprognostic (2.03e-1)" "unprognostic (2.08e-1)" "unprognostic (6.11e-2)" "unprognostic (3.56e-4)" "unprognostic (2.24e-1)" "unprognostic (2.15e-1)" "unprognostic (1.64e-1)" "unprognostic (1.89e-1)" "unprognostic (1.86e-3)" "unprognostic (5.22e-1)" "unprognostic (1.74e-2)" "unprognostic (1.06e-1)" "unprognostic (1.10e-3)" "unprognostic (2.73e-1)" "unprognostic (1.60e-1)" "unprognostic (1.33e-1)" "unprognostic (1.91e-1)" 2.9 5.5 1.4 3.0 8.6 0.8 0.8 4.2 3.4 0.6 53.7 1.2 8.5 0.5 1.4 0.8 0.8 1.5 2.3 2.0 1.2 10.0 13.5 4.6 0.9 1.1 5.0 0.9 29.7 7.9 1.0 23.7 2.8 1.3 1.8 0.7 3.1 0.2 41.2 15.3 5.0 0.3 0.2 1.8 5.3 4.2 9.6 10.9 2.7 6.0 1.3 1.9 1.2 1.1 0.9 1.0 0.4 2.2 0.1 0.1 3.1 0.0 0.2 0.8 1.2 9.0 0.4 5.2 1.4 0.3 2.5 0.1 49.4 0.1 1.0 0.1 20.2 8.2 0.7 7.4 0.1 7.6 7.4 0.0 0.0 0.1 0.0 0.2 0.0 10.9 1.4 0.2 0.1 3.6 9.8 0.8 14.6 0.2 3.2 5.4 6.8 37.2 0.0 0.5 10.7 3.3 0.2 0.7 1.8 3.6 1.8 0.9 0.1 0.1 1.8 0.5 2.5 2.6 0.1 1.5 0.3 5.8 0.8 0.4 0.0 0.0 0.1 0.0 0.1 0.1 0.4 0.1 0.0 0.2 1.7 1.5 0.3 0.1 0.0 0.1 1.6 0.1 1.4 8.6 4.2 3.4 2.0 1.2 1.1 5.0 2.8 0.2 9.6 1.1 0.4 9.6 32.8 2.0 1.5 9.7 10.7 0.0 4.6 6.9 2.0 1.3 9.1 0.0 3.1 5.5 2.1 1.9 0.7 2.1 1.9 0.2 9.0 0.4 0.8 1.4 6.6 1.7 33.9 12.5 1.8 8.9 3.6 1.3 1.3 2.5 4.2 25.4 21.4 1.7 47.8 4.8 0.0 12.4 12.4 8.2 0.0 33.8 44.4 0.0 0.7 1.6 0.0 16.6 0.3 2.0 0.9 0.0 4.8 3.9 10.9 17.7 0.7 0.7 0.0 18.5 1.0 11.6 11.2 1.2 14.8 1.2 5.8 9.2 8.5 1.2 SLC16A6 "MCT6, MCT7" ENSG00000108932 "Solute carrier family 16 member 6" O15403 17 68267026-68291267 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 51.0;epididymis: 33.3;retina: 31.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 22.9;Glandular and luminal cells: 27.4;Kupffer cells: 16.7;Macrophages: 21.8;Rod photoreceptor cells: 45.1" "Group enriched" "Detected in many" 6 "breast cancer: 10.9;melanoma: 11.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 13 "SK-MEL-30: 481.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054459, HPA066328" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" Vesicles "HPA054459: AB_2682494, HPA066328: AB_2685660" "unprognostic (2.53e-2)" "unprognostic (2.09e-3)" "unprognostic (8.41e-2)" "unprognostic (6.94e-2)" "unprognostic (3.10e-1)" "unprognostic (5.26e-3)" "unprognostic (5.08e-3)" "unprognostic (5.39e-2)" "unprognostic (1.63e-3)" "unprognostic (1.08e-1)" "unprognostic (1.35e-2)" "unprognostic (1.44e-2)" "unprognostic (8.78e-2)" "unprognostic (2.23e-1)" "unprognostic (8.16e-3)" "unprognostic (2.09e-2)" "unprognostic (9.46e-2)" 1.5 2.7 3.0 7.2 4.8 9.7 5.8 4.3 4.3 1.6 51.0 0.7 0.5 2.6 33.3 10.9 0.9 1.3 0.9 5.0 5.2 0.7 1.4 3.0 5.3 5.1 4.2 1.5 0.5 0.1 1.7 2.3 5.3 0.6 0.8 31.0 2.2 4.2 5.0 4.5 1.2 0.8 2.4 5.7 1.0 2.3 5.2 1.6 3.5 0.7 4.7 2.1 2.6 3.2 2.1 1.8 0.6 0.8 0.4 0.6 14.2 0.8 18.0 1.7 1.2 0.7 2.5 17.6 1.4 0.0 0.2 0.6 2.5 0.0 0.7 5.4 1.3 1.4 2.2 22.3 3.2 5.7 1.1 0.8 0.2 1.0 1.0 1.7 0.8 2.5 1.1 3.8 0.0 18.1 8.5 3.6 0.2 0.1 1.0 0.1 0.4 2.4 0.8 1.5 4.2 0.3 0.8 10.7 481.5 3.8 15.0 3.5 2.7 5.9 1.1 0.5 2.0 4.2 17.5 14.6 36.0 4.6 2.6 0.8 3.1 0.2 1.8 2.7 0.8 0.4 0.6 1.4 1.9 0.0 0.4 0.8 5.4 0.4 1.4 0.3 1.5 0.9 3.0 4.8 4.3 4.3 5.0 5.2 5.1 4.2 5.3 2.4 5.2 3.2 0.6 0.0 2.5 1.6 1.8 0.3 0.2 0.1 1.2 8.2 2.5 0.9 0.8 0.0 4.0 9.2 22.9 0.4 8.4 0.0 0.0 0.0 0.7 4.7 2.5 3.2 0.0 2.7 6.7 0.0 11.5 0.9 0.5 27.4 1.3 0.1 0.7 0.3 5.6 0.0 6.2 0.0 0.0 16.7 7.0 0.3 0.0 21.8 10.6 4.7 11.1 6.2 5.2 0.5 0.8 0.0 0.0 1.9 5.0 0.2 0.0 0.3 1.6 45.1 0.0 0.8 0.3 1.7 0.7 6.7 0.4 0.4 5.3 0.4 0.1 0.2 SLC18A2 "SVAT, SVMT, VMAT2" ENSG00000165646 "Solute carrier family 18 member A2" Q05940 10 117241093-117279430 "Disease related genes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Disease variant, Dystonia, FDA approved drug targets, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 81.1;cervix: 30.0" "Cell type enriched" "Detected in many" 5 "granulocytes: 636.0" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 11 "hypothalamus: 20.8;midbrain: 81.1;pons: 70.5" "Immune cell enriched" "Detected in some" 15 "basophil: 59.5" "Lineage enriched" "Detected in many" 15 "granulocytes: 59.5" "Cell line enriched" "Detected in some" 19 "HMC-1: 351.0" "Region enhanced" "Detected in many" "midbrain: 62.7" "Region enriched" "Detected in all" 4 "midbrain: 111.6" HPA073224 Enhanced Approved Vesicles,Centrosome NA NA "Cluster 38: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Vesicles, Centrosome" "HPA073224: AB_2732222" "unprognostic (1.49e-1)" "unprognostic (2.48e-1)" "unprognostic (2.33e-3)" "unprognostic (9.00e-2)" "unprognostic (2.85e-1)" "unprognostic (5.33e-3)" "unprognostic (2.23e-1)" "unprognostic (1.71e-2)" "unprognostic (1.40e-1)" "unprognostic (4.55e-2)" "unprognostic (2.00e-1)" "unprognostic (6.06e-3)" "unprognostic (7.94e-5)" "unprognostic (2.95e-2)" "unprognostic (2.31e-1)" "unprognostic (2.43e-1)" "unprognostic (3.57e-2)" 1.1 14.6 0.1 0.9 1.1 2.4 1.8 0.1 0.3 30.0 0.2 2.3 1.5 2.6 1.6 2.5 0.5 3.6 0.7 0.2 20.8 0.9 2.8 7.4 0.6 3.8 81.1 10.4 3.4 0.2 0.2 0.1 70.5 9.2 3.5 0.4 0.8 1.3 0.8 6.3 2.1 2.3 0.0 0.3 4.4 0.9 5.0 6.1 0.0 0.5 0.9 2.9 7.9 0.2 0.2 1.1 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.3 0.6 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.7 18.6 0.1 0.2 0.0 1.0 351.0 0.0 0.0 0.0 0.0 0.2 0.0 3.7 0.0 0.7 0.0 0.1 1.0 0.3 0.2 0.3 0.6 0.2 0.4 0.2 0.0 0.2 3.4 0.7 0.3 0.1 0.0 0.2 0.0 0.1 0.3 0.1 2.5 0.3 0.8 0.5 0.4 0.2 0.4 1.9 0.3 59.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.3 0.0 0.0 3.8 0.0 2.0 0.1 1.1 0.1 0.3 0.2 20.8 3.8 81.1 70.5 0.0 5.0 0.2 0.0 9.6 16.2 1.0 0.2 1.9 0.0 0.0 0.0 2.1 0.2 0.0 0.3 0.0 2.5 0.0 4.2 0.0 5.7 0.4 0.0 0.0 0.0 13.1 16.1 0.7 8.9 4.2 1.1 0.0 0.0 3.4 4.1 112.4 636.0 2.4 9.7 0.3 0.8 0.0 1.7 0.0 0.0 1.0 3.6 0.2 0.6 3.5 1.8 0.0 0.1 0.4 0.0 0.5 0.6 0.1 0.1 4.9 1.9 3.8 0.0 0.1 0.7 0.8 0.0 0.4 1.3 0.2 2.1 0.0 2.7 0.0 5.6 9.8 0.1 0.1 SLC1A3 "EA6, EAAT1, GLAST" ENSG00000079215 "Solute carrier family 1 member 3" P43003 5 36596588-36688334 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 10 "brain: 776.8;choroid plexus: 400.6;retina: 221.1" "Cell type enhanced" "Detected in many" "Astrocytes: 1735.2;Microglial cells: 332.6;Muller glia cells: 472.6;Oligodendrocyte precursor cells: 237.7;Oligodendrocytes: 249.0" "Cancer enriched" "Detected in all" 21 "glioma: 168.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 1.5;intermediate monocyte: 1.2;myeloid DC: 1.6" "Group enriched" "Detected in many" 16 "dendritic cells: 1.6;monocytes: 1.5" "Cell line enhanced" "Detected in many" "AF22: 50.0;CACO-2: 112.6;HaCaT: 71.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002573, HPA037467, HPA037468" Enhanced Supported Approved Nucleoli,Vesicles NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoli, Vesicles" "CAB002573: AB_564088, HPA037467: AB_10795027, HPA037468: AB_10671371" "unprognostic (1.23e-1)" "unprognostic (2.15e-2)" "unprognostic (2.58e-3)" "unprognostic (1.74e-2)" "unprognostic (1.02e-1)" "unprognostic (7.70e-2)" "unprognostic (3.89e-3)" "unprognostic (2.36e-1)" "unprognostic (1.24e-1)" "unprognostic (2.84e-2)" "unprognostic (4.17e-3)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (1.06e-1)" "unprognostic (4.17e-2)" "unprognostic (1.03e-1)" "unprognostic (1.31e-2)" 30.7 16.4 500.4 7.4 544.2 3.3 17.7 549.4 776.8 8.7 400.6 3.0 0.5 1.6 1.1 10.5 6.0 8.0 45.4 514.6 502.5 2.2 3.8 10.2 17.4 477.6 510.1 12.6 5.0 2.2 18.1 20.3 502.4 3.2 1.1 221.1 4.7 4.7 14.1 6.0 3.2 4.1 495.4 9.3 2.2 1.2 532.8 3.6 3.4 9.2 5.4 7.0 5.3 494.9 1.3 0.2 50.0 5.3 5.9 14.3 37.7 0.3 0.0 2.4 4.9 112.6 5.6 0.0 27.8 2.3 1.0 71.4 16.9 9.1 2.2 1.8 33.0 0.0 0.5 0.0 2.5 1.3 0.6 26.9 34.5 14.4 5.3 1.8 0.0 1.1 0.0 0.2 8.7 0.2 0.1 0.1 6.0 0.1 5.9 0.0 0.5 0.0 0.1 3.1 4.7 0.0 5.1 14.6 2.1 24.4 0.2 3.1 0.0 6.2 10.3 0.1 20.7 0.0 0.0 0.3 21.7 37.7 12.6 0.0 1.5 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 500.4 544.2 549.4 776.8 514.6 502.5 477.6 510.1 502.4 495.4 532.8 494.9 1.1 3.2 0.5 1735.2 0.7 10.7 14.3 19.0 83.1 7.1 3.7 3.4 36.0 0.0 3.1 0.0 2.1 32.9 0.1 0.0 0.0 0.8 0.7 16.3 1.2 8.9 0.0 0.8 2.6 0.0 15.9 7.8 2.0 11.7 0.0 0.2 1.1 0.5 41.2 3.3 4.7 0.0 0.0 77.6 5.9 4.1 4.4 59.6 7.2 332.6 3.3 472.6 0.0 237.7 249.0 0.3 0.0 0.0 0.7 5.2 0.0 0.0 5.3 19.1 6.6 2.6 3.1 0.3 0.3 32.7 7.1 9.2 1.0 20.7 0.0 3.6 SLC22A23 "C6orf85, FLJ22174" ENSG00000137266 "Solute carrier family 22 member 23" A1A5C7 6 3268962-3457050 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 50.9" "Cell type enhanced" "Detected in many" "Early spermatids: 86.8;Late spermatids: 229.3;Oligodendrocytes: 285.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 31.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014697 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 28: BEWO - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Vesicles" Cytosol "HPA014697: AB_1844371" "unprognostic (4.58e-2)" "unprognostic (2.48e-1)" "unprognostic (1.05e-1)" "prognostic favorable (6.57e-4)" "unprognostic (5.16e-3)" "unprognostic (3.25e-3)" "unprognostic (1.40e-1)" "unprognostic (4.53e-3)" "unprognostic (9.74e-2)" "unprognostic (2.87e-2)" "unprognostic (1.07e-2)" "unprognostic (2.62e-2)" "prognostic unfavorable (2.39e-4)" "unprognostic (8.91e-2)" "unprognostic (4.30e-1)" "unprognostic (4.06e-2)" "unprognostic (1.74e-1)" 7.3 3.4 17.7 4.5 28.9 9.6 8.4 25.4 25.0 9.1 1.8 18.4 20.7 4.1 12.2 23.7 11.0 4.9 3.6 16.2 18.6 7.7 18.1 8.3 4.4 29.9 29.7 4.1 15.5 27.1 8.8 8.5 30.4 18.6 14.8 4.8 14.6 2.4 8.9 17.1 22.4 2.8 22.1 6.3 26.5 11.5 30.2 7.2 5.6 7.8 5.9 4.3 15.5 50.9 4.3 10.1 20.1 22.6 7.2 7.8 26.6 0.7 0.3 1.2 0.5 22.5 0.7 1.0 2.5 4.8 18.2 6.1 4.2 10.8 0.4 3.5 13.1 10.4 3.9 18.9 1.0 0.7 0.6 2.0 21.3 19.4 1.0 4.3 0.7 5.4 9.6 5.3 0.7 5.3 1.0 2.4 7.1 23.2 3.9 2.2 1.3 18.1 0.1 26.9 2.4 0.3 5.7 7.8 7.0 20.9 31.8 0.2 5.6 12.0 4.0 15.9 2.6 12.7 0.2 0.4 21.2 0.7 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.2 17.7 28.9 25.4 25.0 16.2 18.6 29.9 29.7 30.4 22.1 30.2 50.9 22.6 6.4 17.5 46.7 1.0 11.6 5.0 18.7 4.6 8.0 9.5 8.1 2.8 10.0 18.0 5.5 8.4 16.1 0.5 43.3 0.0 2.9 86.8 11.6 2.5 8.2 4.2 11.0 59.9 8.0 1.3 1.9 39.8 4.1 0.0 13.1 6.4 12.7 12.9 0.0 67.4 49.7 12.2 13.0 3.0 229.3 1.8 4.8 3.6 77.8 6.4 8.6 0.0 45.8 285.5 6.1 20.5 0.7 0.4 13.9 34.3 4.2 42.0 3.5 0.0 4.5 2.6 2.5 1.2 10.3 12.6 9.2 1.3 0.1 25.3 4.5 SLC22A3 "EMT, OCT3" ENSG00000146477 "Solute carrier family 22 member 3" O75751 6 160348378-160452577 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 67.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 78.9;Hepatocytes: 68.8;Leydig cells: 33.8;Pancreatic endocrine cells: 57.3;Skeletal myocytes: 29.8" "Cancer enhanced" "Detected in many" "prostate cancer: 19.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 27.6;HeLa: 38.1;Hep G2: 23.7;OE19: 12.0;RPTEC TERT1: 13.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA029750 Approved Approved Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 15: Hepatocytes - Hemostasis" Vesicles Cytosol "HPA029750: AB_10603888" "unprognostic (8.61e-2)" "prognostic unfavorable (7.19e-5)" "unprognostic (4.14e-1)" "unprognostic (1.49e-2)" "unprognostic (1.38e-1)" "unprognostic (1.87e-1)" "unprognostic (1.28e-1)" "unprognostic (3.36e-2)" "unprognostic (9.74e-2)" "unprognostic (9.36e-4)" "unprognostic (1.33e-2)" "unprognostic (2.58e-2)" "unprognostic (7.28e-2)" "unprognostic (7.96e-2)" "unprognostic (5.21e-2)" "unprognostic (8.13e-4)" "prognostic unfavorable (7.26e-4)" 11.7 15.2 2.1 3.8 2.7 0.0 6.6 3.3 2.1 15.9 1.8 8.8 1.7 18.4 27.6 7.7 18.7 11.0 1.5 2.0 3.5 6.3 34.9 16.4 16.2 6.2 3.8 21.1 0.7 0.2 1.3 44.3 4.5 43.4 2.4 0.2 51.8 52.6 67.4 10.7 5.7 26.3 3.3 0.6 6.0 2.6 4.2 0.5 2.0 8.5 4.9 6.2 15.7 3.2 0.0 27.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.3 1.5 0.0 0.0 0.0 0.0 7.3 0.0 0.0 0.4 0.0 0.0 0.0 38.1 23.7 1.2 0.0 0.0 0.8 6.9 3.4 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.0 12.0 7.7 0.0 0.0 0.0 13.8 0.0 0.0 0.0 3.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.7 3.3 2.1 2.0 3.5 6.2 3.8 4.5 3.3 4.2 3.2 0.6 16.0 78.9 6.2 0.1 4.7 0.3 2.1 2.8 0.2 0.2 0.3 2.9 5.7 6.4 0.0 0.0 0.3 0.1 0.2 5.9 8.2 0.6 0.2 10.2 1.0 0.0 0.0 0.5 3.0 0.3 10.0 12.8 0.3 2.5 0.8 0.0 68.8 0.7 0.0 25.1 1.6 2.0 1.0 2.4 1.6 33.8 0.3 3.6 7.5 0.0 0.0 0.0 19.6 0.2 57.3 0.1 24.5 0.1 6.1 2.1 2.9 0.8 0.1 0.0 29.8 12.3 0.3 0.2 3.7 6.7 0.4 1.2 0.0 2.8 0.8 SLC23A2 "KIAA0238, SLC23A1, SVCT2, YSPL2" ENSG00000089057 "Solute carrier family 23 member 2" Q9UGH3 20 4852356-5010293 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 99.3;choroid plexus: 88.4;retina: 107.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 236.8;Cone photoreceptor cells: 114.7;Excitatory neurons: 102.8;Inhibitory neurons: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052825, HPA059314" Approved Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 56: Bipolar cells - Visual perception" Vesicles "Golgi apparatus" "HPA052825: AB_2681965, HPA059314: AB_2683975" "unprognostic (3.83e-1)" "unprognostic (1.08e-2)" "unprognostic (1.95e-3)" "unprognostic (1.64e-3)" "unprognostic (8.05e-2)" "unprognostic (2.09e-1)" "prognostic favorable (3.35e-4)" "unprognostic (6.22e-3)" "unprognostic (2.08e-1)" "unprognostic (6.36e-3)" "prognostic favorable (7.14e-5)" "unprognostic (1.57e-1)" "unprognostic (1.60e-2)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "unprognostic (1.33e-1)" "prognostic favorable (6.08e-5)" 10.2 99.3 26.3 8.2 27.2 7.8 9.4 24.1 26.0 13.5 88.4 9.4 6.4 12.9 8.7 6.1 15.9 10.1 8.3 28.5 26.7 13.0 57.0 12.1 10.2 28.1 32.0 38.5 10.0 17.7 23.3 8.1 29.5 12.5 6.1 107.2 5.9 10.3 3.3 11.4 12.5 10.0 25.6 20.9 9.4 11.4 34.6 8.2 25.0 4.5 9.9 18.9 8.9 33.1 21.2 24.5 32.2 12.2 22.2 12.4 40.9 8.9 12.1 10.3 9.6 12.7 23.6 9.6 9.4 12.4 29.1 20.1 9.1 24.2 19.2 6.0 16.2 13.3 4.3 48.0 12.5 18.9 7.6 10.6 13.8 25.8 15.4 21.5 15.2 15.5 9.3 7.9 13.7 7.9 20.7 10.5 11.4 16.9 14.9 19.0 21.2 14.3 5.6 34.2 10.7 12.0 17.0 17.7 63.3 11.4 9.8 10.9 13.1 23.0 10.7 27.8 17.4 11.2 22.2 25.5 8.1 11.2 36.8 0.0 1.1 0.1 1.1 0.7 1.0 1.8 0.8 0.8 1.5 1.0 0.8 0.8 1.2 0.3 0.9 2.4 0.5 0.9 26.3 27.2 24.1 26.0 28.5 26.7 28.1 32.0 29.5 25.6 34.6 33.1 9.3 6.4 7.2 50.3 14.5 7.4 4.5 7.0 12.5 236.8 8.3 7.4 7.9 15.7 9.4 14.7 114.7 4.9 12.6 0.8 0.0 5.0 4.6 2.8 10.1 13.0 7.2 8.6 102.8 5.5 6.6 14.2 3.6 1.9 8.2 13.5 17.5 71.3 10.6 85.8 117.4 1.9 0.0 30.2 7.5 9.3 20.2 16.3 16.0 60.0 8.8 24.8 7.2 77.4 78.3 3.4 6.7 29.3 11.9 8.2 0.6 1.3 7.8 71.5 13.1 12.6 12.2 0.6 8.0 5.5 6.1 4.0 8.2 65.6 2.8 14.7 SLC25A25 "KIAA1896, MCSC, PCSCL" ENSG00000148339 "Solute carrier family 25 member 25" Q6KCM7 9 128068201-128109245 "Predicted intracellular proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 136.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 127.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020381 Uncertain Supported Vesicles,Mitochondria "Intracellular and membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 16: U-266 - Nucleosome" "Cluster 44: Endometrium - Transcription" "Vesicles, Mitochondria" "HPA020381: AB_1857037" "unprognostic (4.62e-2)" "unprognostic (2.66e-2)" "unprognostic (2.56e-2)" "unprognostic (1.59e-1)" "unprognostic (2.89e-1)" "unprognostic (1.40e-1)" "prognostic favorable (1.01e-4)" "unprognostic (1.20e-1)" "unprognostic (1.66e-1)" "unprognostic (1.60e-2)" "unprognostic (4.96e-2)" "unprognostic (3.70e-2)" "prognostic favorable (4.65e-6)" "unprognostic (1.21e-1)" "unprognostic (1.05e-2)" "unprognostic (1.66e-3)" "unprognostic (1.42e-2)" 55.3 22.9 16.0 12.5 16.5 9.5 22.9 14.7 19.7 33.2 10.6 17.2 11.9 26.8 3.3 35.0 40.7 39.9 12.8 18.1 17.4 28.6 136.5 27.9 11.2 19.9 18.1 25.3 82.6 19.6 45.7 11.5 17.9 15.2 7.8 31.2 16.5 14.2 82.0 24.4 18.3 26.3 15.4 15.6 23.7 7.6 19.6 15.3 18.9 21.1 6.2 19.0 21.4 14.9 9.5 9.8 13.6 19.8 10.1 8.6 9.0 19.3 17.8 15.9 10.5 17.7 9.7 12.2 5.8 9.0 8.8 16.6 10.8 6.3 6.0 14.3 8.9 7.1 21.6 10.7 16.0 8.3 15.7 11.0 6.0 15.5 11.3 5.2 10.9 20.1 26.1 25.7 10.1 22.9 14.7 8.4 13.8 30.5 15.1 14.3 11.6 26.1 6.1 9.8 33.6 14.5 20.2 12.9 27.8 5.3 14.2 4.7 7.0 17.9 10.6 13.6 19.3 22.3 42.2 13.2 12.1 4.4 15.0 2.6 1.7 0.9 3.0 5.1 1.6 1.2 3.4 3.1 3.1 1.8 2.7 4.9 0.3 1.0 6.1 1.0 2.7 3.2 16.0 16.5 14.7 19.7 18.1 17.4 19.9 18.1 17.9 15.4 19.6 14.9 59.3 22.4 34.2 17.6 9.3 26.1 46.2 24.3 56.3 18.8 71.7 73.5 3.2 58.6 22.8 20.2 127.2 10.1 7.6 45.6 11.7 11.2 0.3 72.0 34.5 44.7 51.7 11.0 19.7 11.5 12.9 21.0 43.8 110.3 8.2 18.7 26.0 84.5 9.1 18.5 20.5 26.5 28.5 20.1 42.9 1.5 9.3 16.8 21.4 13.1 12.6 15.2 12.3 11.1 2.4 12.1 42.7 8.2 14.5 28.6 47.7 10.2 30.8 70.4 19.7 48.1 40.3 5.6 7.9 89.5 43.0 23.0 14.2 11.9 22.3 58.3 SLC25A35 FLJ40217 ENSG00000125434 "Solute carrier family 25 member 35" Q3KQZ1 17 8287763-8295400 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 20.9;Syncytiotrophoblasts: 17.4" "Cancer enhanced" "Detected in all" "endometrial cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051720 Uncertain Approved Vesicles,Mitochondria NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 71: Testis - DNA repair" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "Vesicles, Mitochondria" "HPA051720: AB_2681584" "unprognostic (4.73e-2)" "unprognostic (1.36e-3)" "unprognostic (1.21e-2)" "prognostic favorable (3.37e-7)" "unprognostic (1.61e-2)" "unprognostic (1.20e-1)" "unprognostic (3.52e-2)" "unprognostic (5.27e-2)" "unprognostic (2.58e-1)" "unprognostic (8.30e-2)" "unprognostic (8.96e-3)" "unprognostic (1.18e-1)" "prognostic favorable (1.14e-6)" "unprognostic (5.31e-3)" "unprognostic (2.34e-1)" "unprognostic (1.00e-1)" "prognostic favorable (1.91e-5)" 5.7 8.3 2.9 4.9 3.9 6.1 8.6 3.5 4.4 10.0 4.6 7.7 6.1 13.4 7.6 5.4 7.1 5.2 4.8 2.9 3.2 15.0 4.6 6.8 5.0 3.9 4.0 2.9 12.2 6.1 12.8 4.1 4.1 8.7 5.3 4.5 6.4 5.2 2.2 4.5 7.7 4.1 3.3 8.9 12.5 24.5 4.4 5.2 9.1 1.5 3.5 6.0 5.0 4.2 5.0 13.5 2.4 10.0 7.5 2.9 5.5 3.2 2.8 3.4 3.7 1.6 12.4 5.8 3.3 3.7 7.1 11.0 2.8 3.8 1.9 3.2 3.6 4.8 11.1 1.9 2.7 0.7 12.8 5.9 2.1 6.5 1.2 2.5 5.4 6.8 1.4 2.0 2.9 2.7 5.3 2.7 0.8 3.4 4.4 5.8 1.6 2.6 2.6 12.6 1.2 3.0 9.2 5.4 4.1 2.4 12.2 3.6 7.6 2.3 1.7 5.6 2.7 4.3 2.9 2.1 5.9 8.6 6.1 4.1 5.6 7.6 4.0 8.8 3.3 1.9 3.7 4.3 5.7 3.6 1.3 2.5 1.1 2.8 6.5 3.0 4.1 2.5 2.9 3.9 3.5 4.4 2.9 3.2 3.9 4.0 4.1 3.3 4.4 4.2 3.1 0.0 5.4 5.2 3.6 0.8 1.5 1.4 2.8 4.3 6.3 4.1 1.0 5.7 1.8 11.0 8.4 9.2 2.1 3.8 11.7 2.8 3.8 10.2 1.9 2.8 9.0 4.6 0.5 7.1 2.3 3.0 5.1 10.6 5.1 1.3 1.8 2.8 6.7 1.7 0.7 3.0 2.0 6.4 1.5 5.5 1.5 4.2 0.0 4.7 5.8 7.9 3.1 1.0 2.5 3.2 6.0 1.2 3.7 1.9 2.4 7.3 2.0 9.0 0.0 1.1 1.2 20.9 0.8 1.9 0.3 17.4 3.2 9.1 3.1 1.9 SLC26A11 ENSG00000181045 "Solute carrier family 26 member 11" Q86WA9 17 80219699-80253500 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 58.4;Rod photoreceptor cells: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029893 Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "Golgi apparatus, Vesicles" Nucleoplasm "HPA029893: AB_10600809" "unprognostic (5.86e-2)" "unprognostic (6.66e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (1.55e-5)" "unprognostic (3.80e-2)" "unprognostic (2.63e-3)" "prognostic unfavorable (1.82e-6)" "unprognostic (2.05e-2)" "unprognostic (3.54e-2)" "unprognostic (1.03e-1)" "prognostic favorable (1.43e-5)" "unprognostic (2.86e-1)" "unprognostic (3.50e-1)" "unprognostic (9.54e-3)" "unprognostic (8.40e-2)" "unprognostic (8.69e-2)" "unprognostic (7.32e-2)" 12.2 36.5 27.4 8.9 24.8 16.4 11.8 14.1 23.2 16.3 21.9 12.1 7.2 11.6 8.9 7.5 13.5 7.6 7.1 21.1 45.5 19.1 10.2 18.8 14.1 27.8 33.3 22.5 10.6 11.8 35.1 9.0 30.1 16.8 4.1 11.6 11.3 9.2 5.9 13.0 11.2 6.0 17.7 22.6 10.0 4.8 42.2 3.4 24.8 3.6 5.6 11.6 12.1 17.4 0.7 12.4 14.3 11.1 7.1 5.2 16.1 6.7 8.4 15.6 9.4 13.6 2.5 0.1 13.1 7.4 11.3 4.4 8.0 5.2 6.1 15.7 14.4 0.0 17.5 13.5 18.6 0.0 2.2 9.5 8.4 7.5 3.4 1.4 13.3 2.7 6.4 16.8 9.3 11.6 0.6 0.3 6.5 3.5 11.7 0.5 1.6 5.7 14.2 13.6 5.4 16.9 6.8 17.0 18.3 22.0 20.4 0.3 9.9 11.8 6.9 10.4 0.9 17.8 7.4 1.8 6.2 0.0 10.1 0.0 1.0 0.0 0.7 0.4 1.1 0.2 1.2 1.0 0.6 0.1 1.9 0.8 0.0 0.0 0.1 0.0 1.7 0.9 27.4 24.8 14.1 23.2 21.1 45.5 27.8 33.3 30.1 17.7 42.2 17.4 8.8 6.4 13.4 22.2 3.9 4.6 8.9 5.0 5.2 27.2 9.6 9.9 2.5 5.7 5.6 12.9 58.4 14.5 5.6 3.2 1.9 7.5 0.6 7.1 7.0 12.4 10.2 2.7 13.4 6.0 8.8 8.1 3.6 11.6 1.3 15.4 8.2 2.2 15.2 3.3 17.2 3.2 8.2 11.4 10.5 0.7 17.1 15.1 3.6 12.2 4.2 22.8 5.2 12.1 13.3 3.4 3.9 12.4 2.2 9.0 7.0 6.0 4.4 40.8 32.9 6.4 7.7 0.2 5.3 2.4 4.7 26.0 8.2 16.4 2.6 5.3 SLC26A2 "DTD, DTDST" ENSG00000155850 "Solute carrier family 26 member 2" P50443 5 149960758-149993455 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "intestine: 212.0" "Group enriched" "Detected in many" 4 "Distal enterocytes: 2026.2;Glandular and luminal cells: 684.5;Syncytiotrophoblasts: 808.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "EFO-21: 66.1;RPTEC TERT1: 151.7;TIME: 80.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041957, HPA058090" Enhanced Approved Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 37: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA041957: AB_10795646, HPA058090: AB_2683602" "unprognostic (6.64e-2)" "unprognostic (1.53e-1)" "unprognostic (3.03e-2)" "prognostic favorable (7.29e-4)" "unprognostic (2.59e-2)" "unprognostic (5.64e-2)" "prognostic unfavorable (4.66e-4)" "unprognostic (2.59e-1)" "unprognostic (5.64e-2)" "unprognostic (1.19e-1)" "unprognostic (7.43e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (3.27e-4)" "unprognostic (1.70e-1)" "unprognostic (1.77e-1)" "unprognostic (8.12e-2)" "unprognostic (1.06e-1)" 5.2 30.7 2.2 7.8 2.3 2.5 9.2 9.5 3.8 6.3 4.0 212.0 12.9 9.3 22.8 10.7 5.0 5.5 2.8 2.2 3.5 4.9 1.7 7.3 4.0 3.8 3.4 4.8 3.4 37.7 7.1 34.0 3.5 12.2 189.6 20.8 35.8 18.4 3.9 7.8 16.1 9.3 3.8 3.7 3.3 4.2 3.9 4.2 4.5 3.7 5.9 4.7 3.0 3.4 9.5 8.6 10.5 17.3 12.6 8.8 2.5 8.9 8.0 7.0 8.5 44.7 5.1 7.4 66.1 9.5 16.8 6.8 10.0 20.5 12.4 6.0 6.4 9.3 6.7 5.2 9.4 17.3 15.2 9.8 11.8 11.7 15.2 17.3 16.8 9.0 2.4 7.1 29.6 3.0 6.6 9.1 3.2 3.2 13.5 9.5 16.3 3.9 151.7 41.6 3.2 8.1 15.6 3.6 27.2 8.1 7.3 10.0 80.4 16.0 11.8 14.2 10.7 5.2 7.3 4.3 14.7 20.6 23.5 4.9 0.5 0.3 0.9 0.3 1.1 0.5 0.5 0.8 0.7 0.5 0.8 0.9 0.3 1.1 1.6 0.7 1.1 0.5 2.2 2.3 9.5 3.8 2.2 3.5 3.8 3.4 3.5 3.8 3.9 3.4 47.4 44.8 11.3 3.3 8.5 4.6 13.2 22.9 7.4 17.1 23.8 14.6 7.8 7.2 24.2 33.1 16.7 219.2 11.5 2026.2 1.9 6.1 32.7 237.0 92.3 29.8 21.1 16.6 5.4 9.9 7.7 21.5 5.1 684.5 90.0 29.6 17.2 2.0 30.4 6.7 7.9 52.5 20.3 15.3 11.8 15.7 17.4 17.4 90.7 17.8 19.6 15.2 15.5 16.6 6.0 12.1 177.4 12.4 15.2 15.1 91.7 5.1 26.6 84.5 0.0 18.7 13.9 8.7 11.4 73.9 5.1 808.9 14.0 26.3 208.9 5.5 SLC27A4 "ACSVL4, FATP4" ENSG00000167114 "Solute carrier family 27 member 4" Q6P1M0 9 128340527-128361470 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 53.7;Proximal enterocytes: 100.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007293, CAB009771" Approved Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 45: Intestine - Brush border" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB009771: AB_2270540, HPA007293: AB_1857062" "unprognostic (7.25e-2)" "unprognostic (1.29e-1)" "unprognostic (1.60e-1)" "unprognostic (3.92e-3)" "unprognostic (3.74e-2)" "unprognostic (2.03e-1)" "unprognostic (1.85e-3)" "unprognostic (1.31e-3)" "unprognostic (4.51e-1)" "unprognostic (4.69e-2)" "unprognostic (7.72e-2)" "unprognostic (5.07e-2)" "prognostic favorable (2.61e-5)" "unprognostic (7.29e-3)" "unprognostic (2.11e-1)" "unprognostic (3.45e-2)" "unprognostic (8.01e-3)" 11.4 14.7 22.5 8.5 23.7 2.7 11.6 25.4 30.3 17.2 12.4 22.8 66.9 14.4 6.3 61.8 10.4 7.3 20.4 22.7 25.9 28.8 40.0 11.8 6.4 29.4 23.9 8.3 21.6 15.5 12.1 5.6 28.8 13.1 9.4 6.8 16.4 7.5 16.1 41.8 41.1 9.3 19.7 11.6 16.4 25.8 27.1 5.8 15.5 6.2 9.6 15.5 23.5 24.1 20.8 41.8 21.1 28.1 31.5 9.8 23.3 16.7 11.7 20.3 14.5 30.1 20.7 19.1 13.5 19.8 24.8 70.6 25.5 20.7 6.7 19.5 37.2 11.4 35.6 28.5 17.1 21.0 17.8 12.7 29.6 21.2 17.0 9.4 23.1 26.3 27.5 13.7 20.2 56.2 26.0 22.7 9.2 51.6 63.0 30.4 19.6 36.4 38.1 32.0 34.8 19.2 27.6 57.0 20.3 11.3 26.7 8.8 32.4 23.7 22.9 26.6 22.0 11.4 17.4 6.5 24.3 13.0 27.7 0.0 2.5 1.7 4.7 3.3 3.4 2.1 2.9 3.6 4.4 0.9 2.3 2.4 1.0 1.4 4.3 3.9 2.2 2.4 22.5 23.7 25.4 30.3 22.7 25.9 29.4 23.9 28.8 19.7 27.1 24.1 4.7 0.0 1.1 12.7 2.0 2.8 1.4 4.0 1.2 9.6 5.8 3.0 5.2 7.2 2.8 9.2 12.5 6.1 2.1 53.7 1.9 13.1 4.8 3.6 5.2 5.3 13.1 4.0 27.7 16.0 6.8 3.5 14.3 9.3 8.9 5.9 3.6 20.1 11.3 8.4 29.2 18.6 8.2 6.1 1.9 5.4 1.2 5.4 1.8 15.9 10.0 5.0 6.2 8.5 26.4 26.4 30.0 4.1 3.2 3.2 100.6 9.7 1.8 7.8 6.6 4.4 4.4 11.8 7.9 11.9 6.1 5.2 2.4 7.9 25.7 2.8 SLC29A3 "ENT3, FLJ11160" ENSG00000198246 "Solute carrier family 29 member 3" Q9BZD2 10 71319259-71381423 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 46.1;Extravillous trophoblasts: 45.3;Hofbauer cells: 34.7;Syncytiotrophoblasts: 31.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 31.8;Hep G2: 35.9;RT4: 29.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046085, HPA054976, HPA057905" Approved Enhanced "Golgi apparatus,Vesicles" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus, Vesicles" "HPA046085: AB_2679531, HPA054976: AB_2682659, HPA057905: AB_2683550" "unprognostic (1.73e-1)" "unprognostic (2.38e-3)" "unprognostic (3.23e-3)" "unprognostic (1.07e-1)" "unprognostic (3.06e-2)" "unprognostic (1.73e-2)" "prognostic unfavorable (6.07e-6)" "unprognostic (1.28e-1)" "unprognostic (4.71e-1)" "unprognostic (1.81e-1)" "unprognostic (2.53e-1)" "unprognostic (3.80e-2)" "prognostic unfavorable (5.53e-5)" "unprognostic (3.37e-1)" "unprognostic (1.36e-1)" "prognostic favorable (1.16e-4)" "unprognostic (3.43e-3)" 4.7 2.6 3.1 4.1 3.9 1.1 4.8 3.7 3.7 7.3 2.7 4.4 2.1 6.8 2.5 2.2 5.8 4.4 2.4 3.0 3.6 2.5 9.4 6.7 7.1 4.7 3.7 9.7 5.2 3.5 1.7 11.2 4.2 5.1 3.5 0.3 4.9 2.9 1.4 2.6 3.7 5.1 4.2 6.5 6.1 3.7 4.4 3.7 3.8 0.6 3.8 9.8 4.4 5.0 2.1 12.3 1.8 7.8 6.8 5.3 31.8 2.3 2.2 0.7 0.4 13.8 8.8 7.4 6.4 4.7 3.2 18.3 5.7 2.9 0.1 5.6 5.6 2.2 1.0 35.9 3.3 1.8 4.5 5.2 12.9 0.3 0.6 1.5 3.2 8.5 6.5 6.8 0.9 19.1 4.2 3.8 4.2 19.2 4.5 5.7 0.6 5.9 2.3 29.5 8.5 9.6 6.4 20.3 1.7 5.2 3.2 4.0 5.2 0.2 3.8 2.3 0.1 1.8 3.1 4.0 7.6 24.0 1.3 4.2 19.3 2.2 5.4 15.3 4.6 4.9 4.5 5.1 29.1 1.9 3.5 5.0 1.5 9.4 10.3 20.2 5.5 9.5 3.1 3.9 3.7 3.7 3.0 3.6 4.7 3.7 4.2 4.2 4.4 5.0 2.0 3.2 1.1 2.0 3.1 0.3 1.5 4.0 1.8 2.3 2.7 3.8 0.8 1.5 3.8 0.0 0.0 46.1 6.3 2.6 0.0 6.1 3.6 1.8 3.2 1.8 1.8 4.2 2.4 8.9 45.3 4.7 7.1 2.4 2.5 10.2 3.3 5.4 34.7 0.0 1.3 2.5 8.2 11.8 4.4 15.2 2.8 10.9 1.8 16.9 8.5 3.0 3.1 2.5 2.7 7.9 13.1 1.5 6.0 3.2 0.1 2.0 2.6 0.4 0.0 0.2 2.5 0.6 5.0 0.7 0.0 31.7 2.9 10.0 2.5 1.7 SLC2A8 "GLUT8, GLUTX1" ENSG00000136856 "Solute carrier family 2 member 8" Q9NY64 9 127397138-127408424 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 145.8;Endometrial stromal cells: 86.5;Late spermatids: 310.1;Spermatocytes: 98.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 75.9" "Lineage enriched" "Detected in all" 5 "dendritic cells: 75.9" "Cell line enhanced" "Detected in many" "CACO-2: 122.9;Hep G2: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011935 Uncertain Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 78: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA011935: AB_1849760" "unprognostic (6.49e-2)" "prognostic favorable (2.57e-6)" "unprognostic (9.13e-2)" "unprognostic (1.85e-3)" "unprognostic (4.23e-2)" "unprognostic (9.43e-3)" "unprognostic (2.62e-1)" "unprognostic (1.30e-1)" "unprognostic (6.33e-2)" "unprognostic (1.36e-1)" "prognostic favorable (9.86e-6)" "unprognostic (1.70e-1)" "prognostic favorable (6.55e-6)" "unprognostic (4.25e-2)" "unprognostic (3.55e-1)" "unprognostic (1.59e-3)" "unprognostic (2.04e-3)" 17.3 46.9 23.0 7.5 24.8 3.4 13.1 22.5 22.7 19.7 14.6 42.1 15.7 16.5 13.4 12.0 11.1 6.4 18.2 20.9 18.4 15.4 41.0 11.5 7.4 23.6 23.3 12.0 12.4 6.3 9.9 11.6 20.9 17.8 5.3 3.1 10.2 11.6 33.1 14.2 15.5 6.0 23.5 16.7 23.1 64.2 22.8 1.6 14.8 12.7 3.6 60.6 12.8 25.5 4.9 18.8 8.4 18.5 0.0 0.0 26.3 7.4 4.9 11.5 6.9 122.9 4.5 7.5 16.3 3.9 18.4 25.4 10.1 11.7 2.9 7.2 16.2 1.1 15.4 73.3 10.5 0.0 7.8 0.2 10.6 1.1 4.7 5.7 9.0 10.2 8.1 16.4 4.7 35.1 0.0 0.2 13.4 27.1 29.4 2.9 11.5 20.7 11.0 50.6 13.8 9.6 17.6 29.8 6.6 10.6 19.2 4.3 7.9 0.0 11.7 0.8 16.7 49.7 50.6 11.3 7.8 0.0 8.9 0.0 7.0 16.6 10.4 13.5 7.7 5.0 3.3 7.1 10.6 4.7 0.7 2.5 0.5 3.3 12.5 75.9 15.0 4.7 23.0 24.8 22.5 22.7 20.9 18.4 23.6 23.3 20.9 23.5 22.8 25.5 10.8 9.6 8.4 6.2 6.4 11.1 7.4 8.5 9.6 9.5 12.2 10.7 7.6 8.6 7.8 5.5 10.4 78.3 24.5 12.5 15.6 15.6 145.8 6.0 86.5 10.2 12.1 7.0 7.7 16.7 12.8 11.0 10.7 8.0 7.0 15.9 12.1 26.8 75.0 6.7 7.7 14.9 2.0 16.7 8.5 310.1 10.8 14.9 26.6 2.8 7.2 13.4 13.4 2.0 5.4 17.4 22.3 11.7 8.5 14.1 35.0 14.0 5.3 8.4 13.1 11.6 8.6 98.7 15.5 8.7 10.5 67.3 5.9 9.3 19.8 5.8 SLC30A1 "ZNT1, ZRC1" ENSG00000170385 "Solute carrier family 30 member 1" Q9Y6M5 1 211571568-211579161 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 86.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 94.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015275, HPA049000" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Vesicles "HPA015275: AB_1857083, HPA049000: AB_2680593" "unprognostic (1.13e-1)" "unprognostic (2.67e-3)" "unprognostic (6.94e-2)" "unprognostic (1.81e-3)" "unprognostic (3.47e-1)" "unprognostic (1.80e-1)" "unprognostic (2.27e-2)" "unprognostic (1.82e-3)" "unprognostic (4.72e-1)" "unprognostic (1.01e-1)" "unprognostic (1.42e-3)" "unprognostic (4.78e-2)" "unprognostic (2.23e-2)" "unprognostic (3.03e-1)" "unprognostic (2.55e-1)" "unprognostic (1.02e-1)" "unprognostic (4.53e-2)" 14.8 18.0 15.7 10.9 17.0 29.8 8.5 15.2 19.3 18.6 27.8 15.4 28.2 10.8 9.9 8.0 12.5 12.4 10.0 16.9 15.4 20.5 86.1 7.2 6.1 17.9 17.3 7.8 11.3 10.3 4.6 10.1 16.8 7.8 13.6 6.1 9.3 7.9 1.8 16.0 19.9 11.6 16.7 15.4 9.5 13.4 18.9 4.5 16.9 4.8 7.1 12.2 7.5 13.2 10.3 15.0 7.7 9.9 32.4 14.9 70.5 27.3 19.3 13.8 13.6 6.4 46.6 5.8 24.1 24.4 19.3 17.2 11.5 15.4 16.4 15.0 9.3 4.7 28.8 14.7 18.1 15.8 10.0 22.5 37.5 17.7 28.4 20.5 8.6 3.4 18.7 25.5 17.2 9.1 3.2 9.9 24.2 10.6 12.0 10.0 3.7 20.4 42.5 26.4 7.8 13.7 26.7 13.6 62.7 14.2 7.0 20.2 14.6 10.4 24.8 35.4 22.1 11.9 19.0 4.5 9.8 15.7 9.3 1.4 1.3 0.5 0.4 1.5 0.5 0.2 0.3 0.2 0.9 0.1 0.3 0.4 0.1 0.4 1.2 0.5 0.3 0.4 15.7 17.0 15.2 19.3 16.9 15.4 17.9 17.3 16.8 16.7 18.9 13.2 29.7 9.6 9.8 3.9 8.8 28.6 8.2 3.0 16.5 11.0 24.9 14.7 21.0 18.6 4.2 36.8 6.2 11.6 19.9 54.5 1.9 6.9 44.0 37.0 19.1 27.3 9.5 26.1 0.6 12.5 32.7 15.9 8.6 66.4 5.1 7.5 17.9 94.9 32.0 6.7 0.6 22.8 2.0 27.2 14.5 6.8 9.9 25.5 21.4 3.7 18.8 29.0 1.0 1.0 0.1 9.5 41.7 7.5 8.6 13.9 49.2 29.8 6.4 9.4 6.6 15.9 11.7 37.9 17.4 24.2 46.2 24.5 14.2 14.8 23.3 13.7 SLC30A2 ZNT2 ENSG00000158014 "Solute carrier family 30 member 2" Q9BRI3 1 26037252-26046118 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "pancreas: 99.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 31.0;Endometrial ciliated cells: 30.5;Glandular and luminal cells: 93.7;Proximal tubular cells: 36.2;Syncytiotrophoblasts: 85.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 19.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BEWO: 2.1;RPTEC TERT1: 4.5;WM-115: 3.5" "Region enriched" "Detected in single" 5 "olfactory bulb: 1.2" "Not detected" "Not detected" HPA017979 Approved Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Vesicles "HPA017979: AB_1857085" "unprognostic (4.87e-2)" "unprognostic (6.70e-2)" "unprognostic (3.79e-2)" "unprognostic (1.79e-3)" "unprognostic (1.11e-1)" "unprognostic (2.37e-2)" "unprognostic (2.25e-2)" "unprognostic (2.59e-1)" "unprognostic (3.67e-2)" "unprognostic (1.02e-1)" "unprognostic (6.99e-2)" "unprognostic (1.10e-1)" "prognostic favorable (2.86e-6)" "unprognostic (9.38e-2)" "unprognostic (3.50e-2)" "unprognostic (1.17e-1)" "unprognostic (3.01e-2)" 0.1 1.2 0.4 0.3 0.5 0.6 1.1 1.9 1.0 0.2 0.3 0.5 0.5 0.5 0.3 0.1 0.4 6.7 6.3 0.4 0.3 20.2 0.1 0.2 0.2 0.2 0.0 0.1 99.8 2.2 0.0 4.5 0.1 0.2 0.1 0.5 1.6 2.3 3.8 1.0 0.8 0.1 0.0 0.3 0.3 0.2 0.6 0.0 19.8 0.7 0.1 0.5 0.0 0.2 0.1 0.1 0.0 0.4 0.1 0.0 2.1 0.1 0.1 0.0 0.0 0.3 0.4 0.1 0.4 0.0 0.1 0.3 0.1 0.2 0.0 0.3 0.1 0.2 0.2 0.0 0.0 0.3 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.7 0.0 0.3 0.2 0.3 0.3 0.2 0.0 0.1 0.3 0.3 4.5 0.1 0.4 0.1 0.3 0.5 0.1 0.7 0.3 0.1 0.2 0.2 0.5 0.2 0.1 0.3 0.2 0.3 0.2 0.2 3.5 0.9 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.6 0.3 0.1 0.2 0.1 0.0 0.4 0.5 1.9 1.0 0.4 0.3 0.2 0.0 0.1 0.0 0.6 0.2 0.2 3.2 3.0 0.0 0.6 0.4 0.7 0.0 0.0 4.5 9.1 0.4 13.9 8.6 0.0 9.2 0.0 31.0 0.1 0.5 5.9 11.5 0.0 30.5 9.7 1.0 0.0 0.0 0.0 21.1 2.8 0.5 0.0 93.7 4.5 0.1 0.0 0.0 3.6 0.0 0.0 0.4 0.0 0.0 0.8 0.0 0.3 0.9 3.6 0.0 1.0 0.7 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.6 3.9 36.2 0.0 2.3 6.6 2.1 1.0 0.2 0.4 0.0 0.9 85.1 0.9 0.1 1.1 0.7 SLC30A3 ZNT3 ENSG00000115194 "Solute carrier family 30 member 3" Q99726 2 27253684-27275817 "Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 22.2;epididymis: 68.5;testis: 35.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 8.4;Early spermatids: 17.8;Excitatory neurons: 15.6;Late spermatids: 42.4;Peritubular cells: 15.1;Spermatocytes: 16.6;Spermatogonia: 10.7" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.3" "Group enriched" "Detected in many" 10 "amygdala: 14.5;basal ganglia: 10.3;cerebral cortex: 18.2;hippocampal formation: 22.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 8.8;HAP1: 11.2;Hep G2: 12.0;REH: 22.8;RH-30: 11.0" "Group enriched" "Detected in all" 4 "amygdala: 130.7;basal ganglia: 48.2;cerebral cortex: 110.9;hippocampal formation: 69.1;white matter: 34.7" "Group enriched" "Detected in many" 6 "amygdala: 18.5;cerebral cortex: 55.5;hippocampal formation: 43.0" "HPA060505, HPA067637, CAB079044" Enhanced Approved Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "Nucleoplasm, Nucleoli, Cytosol" "CAB079044: , HPA060505: AB_2684296, HPA067637: AB_2685875" "unprognostic (2.05e-4)" "unprognostic (1.17e-1)" "unprognostic (6.84e-4)" "unprognostic (5.26e-2)" "unprognostic (2.34e-1)" "unprognostic (1.13e-1)" "unprognostic (1.43e-2)" "unprognostic (2.93e-2)" "unprognostic (2.64e-2)" "unprognostic (3.05e-1)" "unprognostic (2.20e-1)" "unprognostic (1.89e-1)" "unprognostic (4.65e-12)" "unprognostic (3.23e-2)" "unprognostic (1.76e-1)" "unprognostic (2.74e-2)" "unprognostic (2.63e-4)" 0.1 2.1 14.5 0.1 10.3 0.3 0.1 0.0 18.2 0.2 0.0 0.1 0.0 0.4 68.5 0.1 0.3 0.1 7.9 22.2 0.0 0.1 0.2 0.2 0.5 0.5 0.0 0.2 0.0 0.5 0.3 0.0 0.8 0.3 0.0 0.2 0.0 0.5 0.1 0.1 0.1 0.1 0.0 0.1 0.1 35.2 0.0 0.0 0.2 0.0 0.1 0.0 0.2 1.5 0.4 1.3 0.1 2.0 0.2 0.2 0.3 0.0 0.0 1.3 1.4 0.5 0.5 0.0 0.1 0.0 8.8 0.3 11.2 0.0 0.3 0.0 1.2 5.9 0.5 12.0 0.2 0.2 2.3 0.0 0.0 0.6 0.0 0.2 0.9 2.9 1.7 0.1 0.2 3.9 0.1 0.4 1.8 0.4 0.0 22.8 11.0 1.4 0.0 0.3 0.0 0.7 2.8 0.0 0.0 0.1 0.0 0.8 0.1 0.3 5.1 0.3 0.2 0.1 0.0 0.0 0.1 0.2 0.2 0.4 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.0 14.5 10.3 0.0 18.2 22.2 0.0 0.5 0.0 0.8 0.0 0.0 1.5 0.3 0.0 0.0 2.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.1 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 17.8 0.0 0.1 0.4 0.0 0.0 15.6 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.4 42.4 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 15.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.3 16.6 10.7 0.0 0.1 0.1 0.1 0.0 0.0 0.0 SLC33A1 "ACATN, AT-1, AT1, SPG42" ENSG00000169359 "Solute carrier family 33 member 1" O00400 3 155821024-155854456 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Cataract, Deafness, Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042430 Uncertain Approved Vesicles,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" "Vesicles, Cytosol" "HPA042430: AB_10806238" "unprognostic (5.12e-3)" "unprognostic (7.78e-2)" "unprognostic (1.13e-2)" "unprognostic (7.21e-2)" "unprognostic (1.88e-2)" "unprognostic (1.34e-1)" "unprognostic (2.73e-2)" "unprognostic (9.57e-2)" "unprognostic (5.65e-2)" "unprognostic (6.61e-2)" "unprognostic (4.36e-2)" "unprognostic (1.19e-1)" "unprognostic (1.93e-1)" "unprognostic (2.08e-2)" "unprognostic (2.92e-1)" "unprognostic (4.73e-2)" "unprognostic (5.74e-2)" 8.8 11.0 3.9 4.9 4.8 2.9 8.4 4.6 4.7 12.3 9.2 7.2 6.9 8.8 12.9 8.0 9.5 7.8 7.6 4.6 5.3 10.4 17.2 8.4 5.0 4.4 4.2 8.0 30.9 11.6 5.9 6.6 4.6 8.3 6.4 6.8 11.2 11.0 4.7 6.4 7.7 7.1 5.2 5.8 8.8 5.4 5.2 7.1 18.8 4.8 6.2 6.8 7.9 7.3 18.9 17.7 7.3 8.3 24.4 23.5 12.9 13.1 21.2 19.8 18.7 8.5 22.0 9.9 24.1 13.1 19.8 17.1 14.3 15.2 20.8 16.5 13.3 11.3 6.5 15.8 41.5 13.3 8.9 18.4 26.7 9.7 49.5 20.5 19.8 12.4 8.6 27.8 14.3 14.3 5.0 3.7 6.8 17.7 14.9 5.6 8.1 29.1 9.7 11.8 7.9 5.9 11.1 24.5 21.4 11.3 8.1 11.2 21.4 10.1 4.9 17.9 13.1 33.2 14.4 12.3 14.6 8.8 14.0 12.7 8.4 6.2 8.9 6.3 9.6 5.4 6.0 6.8 10.4 3.5 5.4 5.5 1.7 6.6 6.5 16.1 5.7 5.9 3.9 4.8 4.6 4.7 4.6 5.3 4.4 4.2 4.6 5.2 5.2 7.3 9.0 22.4 25.0 16.0 14.8 8.9 11.7 20.8 18.2 17.5 16.0 9.0 23.8 18.6 21.5 11.0 27.1 18.2 21.1 14.2 5.9 15.3 13.7 11.2 20.3 13.7 12.5 8.4 17.9 15.4 28.3 19.7 20.9 16.6 12.0 12.8 16.4 64.3 19.5 18.5 17.4 18.1 12.2 14.7 15.8 13.2 18.6 15.2 12.4 10.3 19.0 15.4 12.3 11.1 20.8 14.4 5.3 21.4 33.3 19.5 18.9 17.1 23.4 23.0 13.1 16.0 16.0 19.5 9.2 12.2 9.5 37.6 15.3 10.2 13.9 10.9 SLC35B1 UGTREL1 ENSG00000121073 "Solute carrier family 35 member B1" P78383 17 49700934-49709014 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048655, HPA057418" Approved Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum, Vesicles" Nucleoplasm "HPA048655: AB_2680481, HPA057418: AB_2683432" "unprognostic (1.35e-1)" "unprognostic (2.15e-2)" "unprognostic (1.09e-3)" "unprognostic (6.36e-2)" "unprognostic (8.31e-2)" "unprognostic (2.86e-3)" "unprognostic (6.17e-3)" "unprognostic (4.39e-2)" "unprognostic (2.47e-2)" "unprognostic (4.00e-3)" "unprognostic (3.37e-2)" "unprognostic (4.42e-2)" "prognostic unfavorable (5.69e-7)" "unprognostic (6.28e-2)" "unprognostic (7.88e-2)" "unprognostic (2.58e-1)" "unprognostic (1.44e-2)" 13.4 9.9 16.8 15.6 17.1 19.4 18.6 17.3 20.0 16.7 21.7 19.9 26.8 11.4 52.8 17.2 18.1 12.5 32.2 17.1 20.0 28.8 46.4 15.3 14.3 17.4 17.8 8.5 18.4 31.6 13.7 17.0 17.4 13.7 24.2 17.0 16.4 15.5 61.4 10.8 26.0 15.6 16.5 12.4 17.4 14.0 18.4 15.3 36.0 60.3 21.6 23.0 7.9 17.2 45.2 75.5 52.4 87.7 47.5 32.9 59.7 46.4 77.8 98.7 80.5 156.6 52.3 31.5 104.7 66.7 55.0 32.6 87.1 55.3 103.5 38.3 65.3 38.5 43.8 94.0 85.3 71.9 34.9 31.9 60.3 73.1 83.6 24.6 64.7 46.5 40.0 84.2 68.1 94.2 51.9 52.5 23.6 82.4 92.2 37.4 56.6 85.6 47.1 45.5 45.8 60.4 25.9 21.3 34.0 57.7 68.7 50.0 26.6 74.0 33.3 84.0 61.9 48.3 79.6 42.7 50.2 54.6 63.8 25.1 27.2 10.1 15.8 27.7 12.0 11.6 10.9 15.4 32.1 6.8 11.2 10.0 11.2 13.5 19.3 43.3 13.6 16.1 16.8 17.1 17.3 20.0 17.1 20.0 17.4 17.8 17.4 16.5 18.4 17.2 32.1 16.0 29.7 10.7 37.1 22.3 40.0 56.4 22.8 28.2 37.1 29.0 40.5 21.5 45.3 27.6 35.5 57.8 47.4 34.9 35.2 78.4 52.4 19.1 25.1 39.2 50.6 20.4 11.7 101.7 121.0 28.6 16.3 24.1 42.5 22.8 27.8 56.6 73.5 21.9 10.4 56.2 59.0 28.0 45.2 17.6 30.1 34.0 37.4 4.7 39.6 44.6 26.8 11.6 11.2 77.5 33.2 20.7 103.7 70.1 139.9 51.3 33.9 35.4 13.1 25.3 47.9 63.2 41.2 24.5 25.1 80.4 31.1 24.1 41.7 50.6 SLC35B2 UGTrel4 ENSG00000157593 "Solute carrier family 35 member B2" Q8TB61 6 44254096-44257890 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029638 Approved Approved Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA029638: AB_10602402" "prognostic unfavorable (7.90e-4)" "unprognostic (2.47e-3)" "unprognostic (2.30e-1)" "unprognostic (1.39e-2)" "unprognostic (2.36e-1)" "unprognostic (1.65e-2)" "prognostic unfavorable (8.59e-5)" "unprognostic (3.84e-1)" "unprognostic (2.51e-1)" "unprognostic (7.03e-3)" "unprognostic (4.27e-2)" "prognostic favorable (6.07e-4)" "unprognostic (3.60e-2)" "unprognostic (1.13e-1)" "unprognostic (4.07e-1)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" 20.1 36.7 21.2 19.6 25.7 18.4 25.2 27.0 42.3 23.3 24.1 27.1 19.6 28.5 29.5 17.5 26.2 30.0 26.4 19.5 23.3 30.3 30.6 21.7 21.5 25.8 25.1 21.3 41.8 42.5 14.6 25.0 25.6 24.0 28.8 14.6 46.4 27.4 22.4 21.9 23.9 29.7 26.1 24.7 30.6 14.7 26.1 18.5 24.4 23.7 22.3 28.1 19.5 30.9 87.2 48.8 61.4 117.6 106.4 102.3 44.1 95.1 152.3 89.3 109.4 43.3 79.3 19.2 81.9 117.3 97.7 81.1 42.5 106.3 64.4 57.4 53.3 39.8 37.9 59.5 94.1 85.2 61.5 107.0 112.1 85.5 43.1 129.1 67.4 43.2 56.8 81.4 112.5 106.9 32.5 71.0 27.2 271.3 58.9 30.9 38.3 100.2 100.3 65.5 75.4 71.4 45.9 52.2 109.6 37.6 93.3 75.7 65.8 71.0 46.2 71.3 83.3 62.4 75.7 45.6 95.6 67.6 147.5 51.9 14.5 23.5 33.1 11.4 28.3 19.7 18.6 25.2 12.9 13.2 16.6 22.0 1.3 20.3 3.9 23.5 16.4 17.7 21.2 25.7 27.0 42.3 19.5 23.3 25.8 25.1 25.6 26.1 26.1 30.9 8.0 6.4 11.5 8.5 19.2 13.5 32.0 58.3 23.9 9.7 31.6 30.1 7.8 37.1 34.8 27.6 2.1 59.2 15.3 15.2 13.7 84.0 0.6 16.0 17.8 11.1 19.7 10.5 3.5 73.8 52.1 27.5 14.3 19.5 34.9 11.9 13.6 18.7 38.4 10.1 4.3 21.6 57.0 11.4 10.8 2.3 23.3 22.0 53.4 4.7 22.0 38.8 23.7 9.5 13.8 67.4 25.9 19.9 23.3 36.3 18.8 13.5 18.4 12.5 0.0 18.3 24.5 21.0 60.8 17.4 13.9 35.2 14.0 14.8 31.5 24.2 SLC35F6 "ANT2BP, C2orf18, FLJ20555, TANGO9" ENSG00000213699 "Solute carrier family 35 member F6" Q8N357 2 26764284-26781231 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HHSteC: 129.9;Karpas-707: 117.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034655 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Nucleoplasm, Cytosol" "HPA034655: AB_10696359" "unprognostic (2.26e-1)" "unprognostic (7.45e-2)" "unprognostic (1.74e-1)" "unprognostic (1.54e-1)" "unprognostic (7.71e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.11e-4)" "prognostic unfavorable (3.71e-4)" "unprognostic (3.44e-2)" "unprognostic (1.35e-1)" "unprognostic (3.24e-1)" "unprognostic (2.60e-1)" "unprognostic (3.84e-1)" "unprognostic (1.07e-2)" "unprognostic (9.95e-2)" "unprognostic (1.10e-1)" "unprognostic (1.06e-2)" 18.6 20.7 9.6 7.3 10.5 4.6 16.2 10.1 9.2 14.5 8.4 10.1 7.9 11.9 7.3 22.0 10.7 7.3 13.8 9.6 11.8 19.5 17.7 11.9 6.5 13.9 12.9 8.5 10.3 21.3 10.8 9.4 12.3 11.4 5.7 5.8 14.5 8.1 12.8 21.2 10.0 10.1 10.4 10.8 11.3 5.1 13.0 5.7 16.0 9.9 7.6 12.1 13.0 11.6 24.6 43.6 12.3 32.6 41.7 19.4 20.4 14.9 20.3 16.8 15.2 27.9 44.5 6.6 23.4 18.7 42.0 29.4 18.1 26.9 11.8 11.5 10.1 7.6 16.4 23.3 129.9 7.8 36.4 29.8 26.9 18.9 62.7 7.6 19.9 9.6 14.2 117.3 16.9 40.5 10.0 7.0 7.6 17.2 10.9 8.9 35.9 10.9 44.1 20.3 9.6 12.7 22.8 37.4 25.4 10.1 14.1 8.2 19.2 21.8 24.0 30.7 15.2 23.9 32.6 12.9 23.6 13.4 21.0 12.1 18.1 8.0 11.9 25.6 7.0 4.8 8.2 10.8 11.4 3.6 5.3 7.9 11.7 13.6 30.9 7.8 5.9 9.5 9.6 10.5 10.1 9.2 9.6 11.8 13.9 12.9 12.3 10.4 13.0 11.6 39.0 12.8 10.5 11.8 5.9 17.0 13.2 10.2 7.4 17.2 17.5 10.2 13.5 28.6 11.1 33.1 6.2 24.1 12.0 21.5 7.9 34.2 1.7 13.4 29.7 20.8 9.1 0.8 6.9 38.7 22.3 25.2 12.2 22.8 1.3 11.9 31.8 25.4 51.2 15.2 7.9 11.2 8.2 61.0 16.8 1.5 18.3 28.8 28.4 4.7 19.8 19.2 11.3 9.0 10.8 48.2 14.3 12.0 5.5 18.3 21.5 57.2 9.0 11.1 26.3 17.8 20.2 3.7 7.1 14.9 25.7 38.0 10.6 16.8 11.2 11.7 SLC38A5 "JM24, SN2" ENSG00000017483 "Solute carrier family 38 member 5" Q8WUX1 X 48458537-48470260 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "pancreas: 237.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 196.3;Erythroid cells: 74.3;Exocrine glandular cells: 80.8;Pancreatic endocrine cells: 129.4;Plasma cells: 62.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 214.0;HBEC3-KT: 326.7;HeLa: 300.0;hTCEpi: 237.8;Karpas-707: 282.8;RPMI-8226: 539.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047411 Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" Cytosol "HPA047411: AB_10964355" "unprognostic (2.81e-1)" "unprognostic (4.87e-2)" "unprognostic (7.92e-3)" "unprognostic (1.58e-1)" "unprognostic (1.29e-3)" "unprognostic (1.26e-1)" "unprognostic (7.75e-2)" "unprognostic (5.79e-2)" "unprognostic (1.52e-1)" "unprognostic (3.80e-3)" "prognostic unfavorable (2.13e-4)" "unprognostic (2.99e-2)" "prognostic unfavorable (2.22e-16)" "unprognostic (1.27e-3)" "unprognostic (1.45e-1)" "unprognostic (2.86e-1)" "unprognostic (2.20e-1)" 4.2 1.9 29.9 13.0 21.8 55.7 2.5 22.6 26.3 9.4 10.6 13.2 13.3 4.2 2.7 10.2 4.9 3.7 6.1 21.6 22.5 1.8 0.9 25.3 8.8 30.4 23.1 6.7 237.2 0.4 0.9 1.1 28.0 5.6 16.2 3.4 9.3 8.6 0.6 21.3 9.2 7.0 22.0 13.8 15.9 0.7 30.4 8.5 20.3 1.3 9.1 9.4 8.7 21.1 143.0 0.3 0.1 1.6 2.8 11.6 0.3 9.4 0.0 0.3 0.1 0.4 0.3 147.8 0.2 61.7 0.3 214.0 164.4 326.7 0.0 47.4 0.2 80.7 300.0 102.4 23.2 166.7 0.2 22.0 237.8 2.9 0.6 0.2 2.8 35.5 150.7 282.8 32.2 0.2 36.3 57.9 74.2 0.0 0.7 131.5 0.7 539.6 0.0 0.1 13.1 0.7 0.1 0.9 0.2 1.1 0.5 6.9 4.7 0.6 0.4 0.4 0.4 0.4 1.0 53.0 1.6 0.8 0.7 0.1 0.4 0.4 17.3 0.6 24.2 11.4 18.6 16.4 2.3 8.9 8.7 11.3 0.5 9.6 0.1 13.1 21.7 9.1 29.9 21.8 22.6 26.3 21.6 22.5 30.4 23.1 28.0 22.0 30.4 21.1 2.3 0.0 0.6 0.3 15.4 26.6 2.7 196.3 17.1 3.2 0.2 0.3 0.4 0.0 33.6 5.5 18.8 0.2 6.7 9.9 0.0 5.5 0.4 1.1 9.1 11.8 0.0 74.3 0.3 80.8 0.6 8.9 3.6 2.7 4.5 1.0 0.4 0.4 2.4 0.0 0.5 17.5 4.1 0.3 3.9 1.3 2.5 2.1 8.8 32.8 1.8 0.3 8.2 0.5 0.2 129.4 5.5 1.2 62.3 4.5 1.2 0.0 4.2 0.3 0.0 0.7 4.6 0.1 0.4 6.4 8.5 0.0 9.5 4.6 21.4 1.9 SLC38A9 FLJ90709 ENSG00000177058 "Solute carrier family 38 member 9" Q8NBW4 5 55625845-55773194 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 57.8" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 182.5;Early spermatids: 262.6;Syncytiotrophoblasts: 619.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 110.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043785, HPA061702" Uncertain Supported Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA043785: AB_10961859, HPA061702: " "unprognostic (4.80e-2)" "unprognostic (1.18e-1)" "unprognostic (3.26e-2)" "prognostic unfavorable (7.24e-5)" "unprognostic (2.49e-1)" "unprognostic (8.19e-2)" "unprognostic (8.35e-2)" "unprognostic (7.95e-2)" "unprognostic (5.47e-2)" "unprognostic (9.44e-2)" "unprognostic (1.74e-1)" "unprognostic (4.87e-1)" "unprognostic (4.18e-3)" "unprognostic (1.76e-1)" "unprognostic (2.25e-1)" "unprognostic (2.84e-2)" "unprognostic (1.12e-1)" 6.1 4.8 5.4 8.8 7.3 7.1 8.2 8.1 6.3 6.5 4.1 9.4 8.1 6.6 6.6 8.4 5.0 8.3 3.8 4.3 6.6 7.4 16.6 8.0 11.2 6.3 5.9 5.4 12.1 10.7 3.3 57.8 6.6 6.1 9.8 10.0 6.4 6.0 4.4 7.6 6.6 8.5 5.5 8.4 8.1 19.2 6.3 8.8 7.7 3.8 14.5 8.4 4.8 8.9 17.9 17.3 17.1 20.0 22.0 20.4 110.0 16.5 21.3 18.3 30.4 29.5 27.2 31.6 28.6 12.7 32.1 22.5 20.2 18.2 22.8 15.4 18.4 10.8 16.4 18.7 31.1 18.9 10.8 26.3 21.0 20.2 25.7 13.7 20.0 21.3 20.9 18.6 16.5 15.0 23.6 16.4 29.4 7.2 15.6 17.6 28.6 32.2 24.7 14.0 8.1 14.5 17.3 9.3 25.4 24.0 20.1 34.4 29.6 3.6 11.7 26.8 16.6 20.5 47.6 20.8 10.9 17.4 11.4 3.3 9.3 5.5 5.2 8.7 7.5 7.4 4.5 6.1 8.4 4.2 6.2 5.3 2.0 7.7 6.9 8.0 5.9 4.9 5.4 7.3 8.1 6.3 4.3 6.6 6.3 5.9 6.6 5.5 6.3 8.9 7.3 6.4 3.1 21.9 14.2 3.2 4.2 8.5 2.8 6.6 5.7 3.9 2.8 11.5 9.8 9.2 8.4 182.5 10.4 8.9 1.9 8.9 262.6 4.4 9.2 8.1 4.2 8.4 56.2 11.4 71.5 7.2 8.6 7.3 2.5 8.0 10.4 22.1 26.3 1.7 57.3 4.3 8.2 10.0 8.0 82.4 7.5 11.7 5.4 38.4 11.0 5.6 4.1 55.8 103.2 10.9 9.7 4.9 8.4 4.6 4.4 7.2 6.3 7.4 6.6 3.3 7.0 15.8 6.5 8.1 3.4 619.9 8.7 4.0 5.2 4.7 SLC39A3 ZIP3 ENSG00000141873 "Solute carrier family 39 member 3" Q9BRY0 19 2732204-2740028 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 100.3" "Group enriched" "Detected in all" 4 "Early spermatids: 302.1;Late spermatids: 433.3;Spermatocytes: 185.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-937: 409.6" "Low region specificity" "Detected in all" "HPA042139, HPA058526" Uncertain Approved Vesicles NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA042139: AB_10793875, HPA058526: AB_2683743" "unprognostic (1.81e-1)" "unprognostic (1.47e-2)" "unprognostic (1.16e-1)" "prognostic favorable (9.76e-5)" "unprognostic (2.26e-1)" "unprognostic (2.44e-2)" "unprognostic (9.88e-3)" "unprognostic (1.01e-1)" "unprognostic (6.03e-2)" "unprognostic (3.66e-2)" "unprognostic (4.37e-3)" "unprognostic (4.07e-2)" "unprognostic (1.75e-3)" "unprognostic (9.22e-3)" "unprognostic (6.58e-2)" "unprognostic (7.97e-2)" "unprognostic (1.80e-2)" 17.9 27.0 19.0 14.7 22.0 46.3 17.4 18.3 23.6 19.6 14.8 18.4 16.7 25.1 30.5 17.3 23.2 15.3 23.3 23.6 18.5 19.8 32.8 16.3 19.1 20.0 18.0 13.5 20.7 34.7 27.2 12.3 18.7 19.3 14.4 10.2 21.3 17.8 22.9 14.9 16.5 23.0 16.7 22.7 17.4 100.3 20.1 21.8 20.5 24.7 16.1 22.3 14.4 18.6 53.3 44.1 32.5 80.3 66.1 45.0 30.6 38.6 46.5 71.3 72.4 47.8 35.0 32.2 23.6 68.2 56.3 42.9 50.2 52.7 44.3 0.4 37.1 144.4 31.4 48.9 72.1 123.2 209.5 40.6 83.3 53.1 43.3 25.6 36.9 61.8 162.8 147.6 48.6 35.2 61.4 99.0 34.6 48.8 59.4 81.4 20.9 100.7 34.1 42.7 44.1 40.3 33.9 24.4 82.4 20.9 42.4 162.7 22.4 49.5 27.0 75.6 56.4 38.7 66.6 32.6 37.4 409.6 59.7 41.1 36.0 67.9 35.9 35.6 30.1 53.3 30.5 29.2 48.9 53.7 24.5 29.2 16.7 29.7 34.1 83.9 21.2 35.2 19.0 22.0 18.3 23.6 23.6 18.5 20.0 18.0 18.7 16.7 20.1 18.6 18.1 3.2 2.8 2.6 31.6 10.3 16.6 37.1 2.2 19.2 25.5 23.6 7.8 24.3 22.6 7.3 8.4 37.5 16.8 20.2 17.6 50.7 302.1 17.8 16.4 21.8 24.0 57.6 5.0 61.8 56.3 18.4 10.7 13.3 24.8 24.2 21.8 31.0 64.9 48.8 5.9 19.7 32.6 25.7 12.9 433.3 21.5 39.3 24.9 4.7 26.7 33.5 26.8 6.6 5.6 46.9 25.8 27.8 12.9 33.3 23.0 23.6 17.6 22.0 26.3 14.0 23.6 185.8 29.7 10.5 9.8 26.4 14.5 29.4 25.6 17.6 SLC39A5 ENSG00000139540 "Solute carrier family 39 member 5" Q6ZMH5 12 56230049-56237846 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 32 "intestine: 237.4;kidney: 110.0;liver: 171.1;pancreas: 306.8" "Cell type enriched" "Detected in some" 4 "Proximal enterocytes: 798.4" "Cancer enhanced" "Detected in many" "colorectal cancer: 30.6;liver cancer: 36.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 53 "CACO-2: 39.9;Hep G2: 58.5" "Region enhanced" "Detected in single" "basal ganglia: 1.1" "Not detected" "Not detected" HPA018423 Approved Nucleoplasm,Vesicles NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" Vesicles Nucleoplasm "HPA018423: AB_1857154" "unprognostic (5.94e-3)" "unprognostic (8.29e-2)" "unprognostic (1.82e-2)" "unprognostic (2.19e-7)" "unprognostic (1.73e-1)" "unprognostic (7.79e-2)" "unprognostic (1.56e-1)" "unprognostic (1.36e-1)" "unprognostic (1.08e-1)" "unprognostic (1.32e-1)" "unprognostic (7.33e-2)" "unprognostic (2.93e-3)" "prognostic favorable (5.05e-4)" "unprognostic (2.75e-1)" "unprognostic (1.15e-1)" "unprognostic (1.23e-1)" "unprognostic (1.96e-4)" 0.3 0.1 0.2 5.5 0.2 0.1 0.3 0.5 0.4 0.3 0.2 73.7 237.4 0.4 0.0 0.1 0.3 6.5 0.2 0.1 0.1 110.0 171.1 0.2 0.4 0.2 0.1 0.4 306.8 0.0 0.2 0.1 0.1 0.3 45.9 6.4 0.1 0.3 0.1 0.3 219.0 2.6 0.1 0.3 1.4 0.2 0.1 0.0 0.3 0.2 0.0 0.2 0.2 0.1 0.0 0.3 0.1 0.2 0.2 0.3 0.5 0.0 0.0 0.1 0.0 39.9 0.4 0.1 0.1 0.1 0.0 0.2 0.0 0.3 0.0 0.6 0.1 0.2 0.2 58.5 0.2 0.1 0.2 0.2 0.1 0.2 0.0 0.1 0.0 0.1 0.1 0.3 0.0 0.2 0.0 0.8 0.0 0.9 0.1 0.2 0.2 0.3 0.5 0.1 0.3 0.4 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.5 0.4 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.0 1.4 0.6 0.1 0.0 0.0 0.9 0.1 0.3 0.2 15.7 0.0 3.7 116.7 0.0 0.0 171.9 19.6 0.3 0.6 0.0 0.1 0.2 25.3 2.7 0.2 20.6 0.0 0.1 0.0 0.0 0.0 0.0 2.2 138.9 0.1 0.0 0.2 112.7 0.0 1.6 1.2 1.4 0.0 1.3 0.0 0.0 0.6 0.6 0.0 0.0 0.1 7.4 192.8 0.0 0.0 0.1 798.4 169.9 0.0 1.8 0.0 0.2 0.2 0.0 0.0 0.0 0.4 0.0 0.8 0.0 168.7 0.0 SLC43A1 "PB39, POV1, R00504" ENSG00000149150 "Solute carrier family 43 member 1" O75387 11 57484534-57515780 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 128.6;pancreas: 233.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 47.1;Erythroid cells: 82.9;Exocrine glandular cells: 35.4;Hepatocytes: 138.2" "Cancer enhanced" "Detected in all" "liver cancer: 45.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 62.7;NB-4: 74.3;U-937: 70.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018813, HPA018826" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus, Vesicles, Plasma membrane" "HPA018813: AB_1857164, HPA018826: AB_1857165" "unprognostic (3.04e-1)" "unprognostic (1.15e-1)" "unprognostic (9.19e-2)" "prognostic favorable (3.19e-4)" "unprognostic (2.51e-2)" "unprognostic (5.48e-2)" "unprognostic (2.32e-1)" "unprognostic (6.71e-3)" "unprognostic (1.63e-1)" "unprognostic (3.12e-2)" "unprognostic (6.06e-2)" "unprognostic (2.72e-1)" "prognostic unfavorable (2.97e-5)" "unprognostic (1.39e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (7.30e-2)" 13.9 10.7 3.6 4.7 4.2 35.7 11.1 2.7 5.0 13.1 2.7 15.7 8.7 12.6 10.3 4.4 13.5 18.2 8.6 3.6 2.8 7.3 128.6 9.9 7.4 3.8 3.2 20.3 233.2 1.8 4.4 6.3 3.5 12.8 9.4 1.3 13.8 6.2 17.1 18.8 9.2 8.7 2.7 8.5 30.4 3.4 3.4 2.1 12.7 9.1 6.6 16.2 9.9 3.9 1.1 1.7 1.8 20.3 25.7 18.8 0.2 10.4 13.8 3.0 7.6 6.5 2.8 59.5 2.7 7.9 3.9 1.0 18.1 1.2 3.7 2.8 4.6 30.9 0.5 62.7 33.7 54.3 7.2 23.8 4.4 5.2 23.2 7.3 13.4 34.7 43.9 10.7 3.8 2.3 0.5 74.3 6.6 27.0 13.6 51.0 9.8 27.2 0.5 0.1 23.5 3.6 1.9 0.3 23.8 0.5 1.6 27.3 5.5 3.1 7.1 26.2 1.7 12.1 4.3 35.3 1.5 70.6 4.2 11.1 6.2 0.7 10.9 2.4 9.2 2.9 4.9 7.7 8.4 1.5 4.9 6.9 0.5 7.5 0.2 1.9 9.5 5.5 3.6 4.2 2.7 5.0 3.6 2.8 3.8 3.2 3.5 2.7 3.4 3.9 4.4 0.0 7.3 1.6 3.3 7.0 1.6 0.0 3.4 5.7 1.8 2.4 6.8 47.1 0.6 0.0 0.0 0.2 3.6 3.1 3.9 3.4 21.5 5.3 6.0 4.7 6.0 82.9 3.5 35.4 0.4 10.9 4.6 13.4 3.8 1.3 15.4 138.2 7.4 0.0 1.4 8.8 0.0 8.1 2.9 14.8 15.5 3.2 5.4 5.6 1.3 0.2 5.2 4.0 0.6 11.1 2.9 7.9 6.2 3.2 0.3 0.1 0.7 0.4 6.6 6.4 7.7 0.7 1.5 0.3 3.7 0.1 6.4 2.9 9.0 0.9 SLC43A3 "DKFZp762A227, Eeg1, FOAP-13, PRO1659, SEEEG-1" ENSG00000134802 "Solute carrier family 43 member 3" Q8NBI5 11 57406954-57427580 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 146.9" "Cell type enhanced" "Detected in many" "Ductal cells: 75.5;granulocytes: 67.0;Hofbauer cells: 73.7;Langerhans cells: 74.6;Sertoli cells: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 105.7;intermediate monocyte: 127.0;myeloid DC: 85.8;non-classical monocyte: 146.3;plasmacytoid DC: 85.7" "Group enriched" "Detected in all" 4 "dendritic cells: 85.8;monocytes: 146.3" "Cell line enhanced" "Detected in many" "HL-60: 513.8;HMC-1: 428.4;RPMI-8226: 570.9;WM-115: 532.1" "Region enhanced" "Detected in many" "olfactory bulb: 10.3" "Low region specificity" "Detected in all" "HPA030551, HPA077244" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Nucleoplasm, Plasma membrane" "HPA030551: AB_10604094, HPA077244: AB_2732335" "unprognostic (2.64e-1)" "unprognostic (7.63e-2)" "unprognostic (9.67e-3)" "unprognostic (7.41e-3)" "unprognostic (6.59e-3)" "unprognostic (5.30e-3)" "unprognostic (1.29e-1)" "unprognostic (4.91e-2)" "unprognostic (1.36e-1)" "unprognostic (2.26e-1)" "unprognostic (5.73e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (3.97e-13)" "unprognostic (8.16e-2)" "unprognostic (1.77e-1)" "unprognostic (8.34e-2)" "unprognostic (1.00e-1)" 61.4 16.8 5.2 34.8 5.9 58.0 50.3 5.9 7.3 40.2 6.8 23.7 8.3 28.1 4.5 34.8 30.0 28.5 34.8 5.5 7.1 15.9 146.9 46.9 26.5 6.7 6.4 24.3 13.7 3.9 4.9 14.3 7.3 14.4 11.8 0.9 35.2 7.5 15.6 34.6 20.6 25.5 6.3 20.8 20.1 4.7 11.1 23.2 76.3 13.3 28.9 30.7 28.2 8.5 289.2 0.0 16.0 0.4 52.9 76.9 0.7 22.0 93.0 31.6 54.1 0.0 61.4 165.0 9.8 52.0 16.3 161.8 47.0 28.8 63.3 1.0 0.2 257.3 93.0 0.0 106.6 513.8 428.4 231.7 0.9 306.5 3.5 22.9 89.7 75.0 299.8 154.4 123.7 0.6 108.6 328.2 24.3 0.0 5.3 221.8 3.3 570.9 76.1 0.0 38.0 0.0 62.2 1.4 263.5 1.5 24.1 77.3 48.1 1.5 81.4 209.2 62.5 0.3 0.9 41.3 187.3 183.2 532.1 15.2 105.7 23.4 19.6 127.0 22.2 9.6 13.5 26.8 85.8 7.1 10.4 10.5 9.0 3.9 146.3 85.7 26.5 60.7 5.2 5.9 5.9 7.3 5.5 7.1 6.7 6.4 7.3 6.3 11.1 8.5 19.8 16.0 49.1 1.6 6.1 46.8 7.4 30.8 48.3 0.5 8.0 14.2 3.7 28.6 26.1 1.8 0.0 0.6 11.9 0.3 0.0 75.5 1.0 1.0 3.1 33.0 0.0 38.3 0.1 6.4 5.0 33.4 2.0 3.0 67.0 2.9 14.3 61.7 73.7 0.0 0.2 0.6 16.2 21.0 74.6 1.7 9.9 47.0 30.2 8.4 10.2 0.6 3.1 8.5 0.8 9.4 0.5 12.4 22.5 14.5 0.0 0.1 4.9 0.1 65.7 15.5 22.0 0.7 1.1 13.6 17.6 0.8 11.8 12.3 1.2 3.0 SLC44A2 CTL2 ENSG00000129353 "Solute carrier family 44 member 2" Q8IWA5 19 10602457-10644557 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 171.1;Extravillous trophoblasts: 257.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 333.2;SK-BR-3: 306.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003228, HPA070799" Approved Approved "Vesicles,Cell Junctions" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Vesicles, Cell Junctions" "HPA003228: AB_1080009, HPA070799: AB_2686314" "unprognostic (6.35e-3)" "unprognostic (5.75e-2)" "unprognostic (4.34e-1)" "unprognostic (3.06e-3)" "unprognostic (4.38e-2)" "unprognostic (8.41e-3)" "unprognostic (1.64e-1)" "unprognostic (2.52e-1)" "unprognostic (2.66e-2)" "unprognostic (4.32e-1)" "prognostic unfavorable (6.01e-4)" "unprognostic (8.63e-2)" "prognostic favorable (1.71e-5)" "unprognostic (1.28e-1)" "unprognostic (1.67e-1)" "unprognostic (8.21e-3)" "unprognostic (3.61e-2)" 74.7 33.2 69.6 43.9 85.0 65.0 72.7 78.4 67.4 64.6 33.4 58.3 26.7 43.0 36.2 81.6 59.0 55.8 71.4 62.7 69.7 68.7 17.8 98.5 75.3 99.6 76.5 32.3 41.2 48.7 20.5 157.5 87.0 43.8 49.5 29.1 55.5 65.8 141.2 78.3 50.8 43.6 84.3 115.5 112.9 82.5 79.1 48.8 64.9 92.4 77.7 56.3 69.2 97.6 333.2 8.3 70.0 42.1 103.9 63.5 201.1 69.6 169.5 112.3 131.6 75.6 154.9 65.6 91.1 193.9 13.6 254.1 10.7 53.2 71.6 1.7 9.3 42.0 39.3 3.1 115.0 0.6 33.9 69.2 69.8 42.3 37.2 91.0 86.8 30.2 20.2 10.8 172.6 243.6 35.1 32.1 24.9 96.9 29.3 74.1 102.7 2.9 37.1 171.8 6.9 42.0 56.7 306.1 7.7 73.8 123.0 3.2 79.8 50.1 18.4 60.5 18.0 4.0 7.9 64.8 12.5 29.1 57.3 146.3 39.4 227.9 114.1 113.0 90.4 92.1 78.5 87.4 20.7 94.8 83.3 87.1 482.8 79.2 278.3 100.4 95.7 147.4 69.6 85.0 78.4 67.4 62.7 69.7 99.6 76.5 87.0 84.3 79.1 97.6 84.0 54.5 29.1 32.3 53.4 9.7 17.3 17.2 13.1 12.3 45.8 29.1 38.6 28.6 47.7 92.0 14.6 137.8 51.9 49.9 1.9 44.1 171.1 15.8 31.4 52.7 9.6 45.0 14.3 44.3 257.0 22.6 84.6 38.6 20.3 7.1 75.7 1.9 37.0 3.3 15.5 17.7 14.2 38.7 3.9 35.1 38.8 22.8 5.4 15.9 10.2 36.4 88.6 18.6 18.4 41.1 31.9 56.4 18.9 9.8 20.1 3.7 19.0 3.0 59.2 26.3 29.4 3.2 2.9 33.5 8.5 93.4 41.2 6.8 23.4 20.6 SLC45A3 "IPCA-2, IPCA-6, IPCA-8, PCANAP2, PCANAP6, PCANAP8, prostein" ENSG00000158715 "Solute carrier family 45 member 3" Q96JT2 1 205657851-205680509 "Cancer-related genes, Predicted membrane proteins, Transporters" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "prostate: 306.4" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 19.9;granulocytes: 119.2;Oligodendrocytes: 47.1;Prostatic glandular cells: 67.2" "Cancer enriched" "Detected in all" 49 "prostate cancer: 539.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 382 "basophil: 40.5" "Lineage enriched" "Detected in single" 382 "granulocytes: 40.5" "Cell line enriched" "Detected in many" 29 "HMC-1: 834.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA019073, HPA019075" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 35: Glandular cells - Unknown function" Vesicles Nucleoplasm "HPA019073: AB_1857177, HPA019075: AB_1857179" "unprognostic (1.80e-1)" "unprognostic (1.08e-3)" "unprognostic (3.13e-2)" "prognostic unfavorable (4.04e-5)" "unprognostic (6.93e-2)" "unprognostic (2.36e-2)" "unprognostic (1.15e-1)" "unprognostic (1.50e-1)" "unprognostic (1.84e-1)" "unprognostic (1.10e-1)" "unprognostic (2.90e-2)" "unprognostic (1.18e-1)" "unprognostic (3.03e-2)" "unprognostic (3.16e-1)" "unprognostic (1.55e-1)" "unprognostic (1.96e-1)" "prognostic favorable (7.33e-5)" 1.4 3.6 6.7 3.2 19.5 0.8 1.6 17.6 13.4 3.7 1.9 4.8 4.6 1.7 0.5 1.6 2.1 3.8 1.5 8.0 10.3 2.1 11.2 3.4 2.7 25.1 17.3 2.7 0.8 0.3 4.7 0.5 21.8 306.4 3.2 0.1 2.8 0.6 5.6 1.5 4.8 1.0 12.6 12.4 16.8 1.4 16.6 0.5 1.0 2.3 0.8 2.8 1.1 44.7 9.7 3.0 2.8 2.7 0.0 0.1 2.2 1.3 0.3 3.3 2.7 7.1 18.0 2.7 4.6 0.3 3.0 3.5 1.6 3.3 0.5 3.9 2.9 29.0 0.6 2.0 1.9 5.0 834.2 0.3 1.1 2.3 0.0 2.2 9.4 4.5 4.9 1.7 1.4 2.3 0.8 8.5 12.2 16.7 10.7 1.0 4.1 1.5 3.7 13.7 1.2 2.9 1.5 20.6 3.9 2.3 4.7 1.4 9.6 1.4 9.5 3.5 7.1 0.4 0.6 0.4 1.8 1.5 7.1 40.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 6.7 19.5 17.6 13.4 8.0 10.3 25.1 17.3 21.8 12.6 16.6 44.7 0.2 0.0 3.2 1.0 4.0 0.0 1.0 0.6 0.0 0.4 1.5 1.8 2.0 2.8 1.0 1.8 0.0 0.5 0.1 5.7 0.0 1.7 0.2 1.9 0.2 1.7 0.0 3.4 0.2 0.5 0.1 0.7 19.9 0.2 119.2 0.2 0.7 6.6 1.9 0.0 0.3 6.9 2.0 1.0 0.3 0.4 1.8 2.0 0.0 0.0 0.6 0.1 0.0 2.0 47.1 3.9 8.0 1.5 0.3 67.2 0.9 1.8 3.2 0.1 6.6 0.1 0.8 0.0 2.6 0.4 0.1 0.0 0.9 0.2 6.7 0.9 SLC48A1 "FLJ20489, hHRG-1, HRG1" ENSG00000211584 "Solute carrier family 48 member 1" Q6P1K1 12 47753916-47782751 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 135.6" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 100.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "EFO-21: 102.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065396, HPA073994" Approved Supported Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "HPA065396: , HPA073994: " "unprognostic (9.60e-2)" "prognostic favorable (4.27e-4)" "unprognostic (1.13e-2)" "unprognostic (1.18e-2)" "unprognostic (1.22e-1)" "unprognostic (2.79e-1)" "prognostic unfavorable (9.39e-5)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (9.88e-2)" "unprognostic (1.54e-2)" "unprognostic (6.63e-3)" "prognostic favorable (1.34e-6)" "unprognostic (1.45e-1)" "unprognostic (5.96e-2)" "unprognostic (1.52e-1)" "unprognostic (2.72e-2)" 27.5 37.4 98.8 6.9 131.6 12.3 27.6 116.7 104.3 26.8 58.5 26.8 7.4 20.2 16.2 28.9 28.4 15.4 29.0 96.2 99.8 44.1 15.2 22.3 7.0 125.5 127.0 53.1 19.5 29.4 17.7 17.7 113.4 20.4 10.6 11.2 20.2 22.7 29.9 22.0 14.3 16.6 103.2 25.8 22.1 9.9 126.8 7.9 52.6 21.5 8.2 27.6 22.6 135.6 11.9 36.3 5.7 42.8 36.4 15.5 12.3 8.3 18.3 7.8 8.0 11.7 31.0 7.2 102.7 23.3 15.5 45.4 7.3 9.6 6.0 59.1 6.8 49.4 30.4 16.1 20.8 13.3 27.9 9.2 19.3 11.2 13.6 40.6 22.1 20.0 13.1 28.3 5.1 24.7 6.5 13.7 3.9 21.9 17.1 6.0 1.6 39.0 31.5 31.3 7.3 3.3 11.0 13.8 7.8 10.2 46.0 12.2 12.3 10.9 14.3 21.1 6.0 21.6 14.3 2.2 14.2 62.8 6.7 0.1 17.9 12.4 5.2 13.5 4.7 10.4 6.4 5.5 12.9 9.9 7.7 6.4 36.7 2.0 7.7 2.6 5.5 6.3 98.8 131.6 116.7 104.3 96.2 99.8 125.5 127.0 113.4 103.2 126.8 135.6 35.2 9.6 13.5 35.3 6.2 6.6 9.7 6.4 22.2 11.1 15.5 15.2 16.4 20.0 5.5 51.5 2.1 9.5 2.3 9.0 23.5 10.4 8.5 10.9 6.2 22.3 8.4 53.0 9.1 9.8 2.3 15.6 4.6 18.0 1.3 16.4 16.8 11.8 24.1 15.2 8.3 13.5 6.1 18.0 9.9 12.5 32.6 14.1 5.4 8.4 28.4 26.8 2.1 11.1 100.3 6.6 5.2 23.0 10.1 12.9 9.2 34.9 2.3 11.2 6.6 11.9 11.6 4.1 10.5 20.9 11.9 3.6 3.3 18.0 7.5 11.6 SLC49A4 "DIRC2, FLJ14784, RCC4" ENSG00000138463 "Solute carrier family 49 member 4" Q96SL1 3 122795069-122881139 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 44.0;Extravillous trophoblasts: 61.2;Syncytiotrophoblasts: 226.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072579 Supported Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA072579: AB_2686536" "unprognostic (1.40e-1)" "unprognostic (8.53e-3)" "unprognostic (1.20e-1)" "unprognostic (1.09e-1)" "unprognostic (1.16e-1)" "unprognostic (5.36e-2)" "prognostic unfavorable (7.48e-4)" "unprognostic (9.74e-2)" "unprognostic (2.58e-1)" "unprognostic (3.95e-2)" "prognostic unfavorable (5.81e-5)" "unprognostic (1.87e-1)" "prognostic favorable (8.81e-11)" "unprognostic (2.36e-1)" "unprognostic (2.64e-1)" "unprognostic (1.73e-1)" "unprognostic (7.13e-2)" 4.4 5.0 4.9 2.7 5.1 5.9 3.1 4.9 5.3 3.0 6.2 4.1 1.9 2.6 3.8 5.6 3.1 3.7 6.4 5.7 5.9 4.6 3.5 5.2 2.0 4.8 5.6 2.2 6.5 12.7 2.4 7.6 5.6 4.9 4.5 5.7 3.7 3.6 15.9 6.6 2.6 2.7 5.2 2.8 3.1 2.5 5.6 1.9 5.2 14.0 2.5 4.0 2.6 5.9 7.4 6.1 5.9 3.3 7.5 6.1 19.6 3.1 6.7 4.9 5.0 14.4 8.0 1.0 3.9 3.5 10.9 10.5 4.3 5.6 4.7 1.6 3.2 1.2 3.3 6.2 5.5 0.7 0.7 5.0 15.0 3.5 5.9 7.6 5.6 2.0 0.7 1.3 6.3 3.3 0.9 0.8 5.3 2.5 9.8 2.0 13.3 1.5 7.0 8.4 6.1 4.6 9.1 4.1 8.4 3.7 4.8 1.6 8.0 7.6 2.8 4.6 2.6 1.3 1.2 0.4 3.8 1.3 4.2 0.0 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.9 0.0 0.2 0.0 0.0 0.0 4.9 5.1 4.9 5.3 5.7 5.9 4.8 5.6 5.6 5.2 5.6 5.9 3.5 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.0 44.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 61.2 2.4 0.0 0.0 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 226.6 0.4 0.0 0.0 0.0 SLC4A11 "BTR1, CDPD1, CHED2, dJ794I6.2, FECD4, NaBC1" ENSG00000088836 "Solute carrier family 4 member 11" Q8NBS3 20 3227417-3239559 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Ion transport, Symport, Transport" "Corneal dystrophy, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 51.3;salivary gland: 54.0;thyroid gland: 60.9" "Cell type enhanced" "Detected in many" "Club cells: 25.5;Collecting duct cells: 112.2;Ionocytes: 79.3;Respiratory ciliated cells: 48.1;Sertoli cells: 26.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 70.6;Hep G2: 43.0;RT4: 30.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA018120, HPA058377" Uncertain Uncertain Nucleoplasm,Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Vesicles "HPA018120: AB_1857186, HPA058377: " "unprognostic (2.33e-1)" "prognostic favorable (9.03e-4)" "unprognostic (1.18e-2)" "unprognostic (3.05e-2)" "unprognostic (1.00e-1)" "unprognostic (6.52e-2)" "unprognostic (9.66e-3)" "unprognostic (3.73e-2)" "unprognostic (3.10e-3)" "unprognostic (1.52e-3)" "unprognostic (2.94e-1)" "unprognostic (2.64e-1)" "prognostic favorable (6.21e-6)" "unprognostic (7.37e-2)" "unprognostic (4.30e-1)" "unprognostic (2.33e-1)" "unprognostic (6.89e-3)" 2.4 6.9 4.5 0.7 3.5 0.4 3.4 2.3 3.1 10.9 5.6 0.4 0.1 0.5 2.6 16.5 1.7 1.1 0.8 2.9 1.4 51.3 0.2 2.0 1.4 2.0 2.3 0.2 0.5 0.6 4.3 0.2 2.6 5.4 0.3 0.4 54.0 7.0 5.2 12.8 0.6 0.3 0.8 0.7 2.5 5.9 4.3 1.0 60.9 0.1 1.8 3.4 5.8 1.9 11.0 15.5 1.8 7.9 5.1 1.3 21.1 5.4 3.4 2.8 1.6 1.1 14.1 0.0 6.1 1.9 6.6 70.6 8.3 16.8 0.5 0.1 3.2 0.7 7.5 43.0 3.2 4.0 13.6 0.7 6.8 3.4 3.2 2.3 7.0 9.8 1.6 9.7 2.9 7.2 0.5 0.4 12.1 13.6 20.7 2.6 10.3 3.5 16.9 30.7 0.9 4.9 2.7 17.5 0.3 5.4 6.7 7.0 12.1 2.1 7.0 0.5 2.7 0.4 0.6 0.1 0.1 2.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 4.5 3.5 2.3 3.1 2.9 1.4 2.0 2.3 2.6 0.8 4.3 1.9 0.8 0.0 0.0 1.6 0.0 0.8 2.2 16.3 8.0 0.2 4.9 4.4 1.1 0.0 25.5 112.2 0.0 0.1 0.6 0.8 0.0 0.7 5.8 2.3 0.6 0.7 0.0 0.0 0.3 0.5 0.1 0.3 5.1 4.2 0.0 0.2 1.1 0.0 0.4 0.0 0.1 0.2 79.3 0.3 0.0 2.2 0.0 0.5 0.0 0.0 0.6 0.1 0.0 0.0 0.3 3.0 1.3 0.4 0.0 3.7 0.0 0.5 48.1 0.2 26.3 0.6 5.8 3.0 4.7 3.3 0.4 0.0 0.2 0.1 0.2 5.7 SLC4A1AP "HLC3, kanadaptin" ENSG00000163798 "Solute carrier family 4 member 1 adaptor protein" Q9BWU0 2 27663471-27694976 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 143.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036679 Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Vesicles, Plasma membrane" "HPA036679: AB_2675244" "unprognostic (5.63e-2)" "unprognostic (1.01e-1)" "unprognostic (4.62e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (2.21e-1)" "unprognostic (7.89e-3)" "prognostic unfavorable (3.76e-7)" "unprognostic (1.32e-1)" "unprognostic (7.74e-2)" "unprognostic (1.83e-2)" "unprognostic (1.06e-1)" "unprognostic (9.66e-2)" "unprognostic (9.68e-2)" "unprognostic (2.29e-2)" "unprognostic (1.42e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (1.79e-4)" 13.7 16.6 15.3 16.1 16.2 15.8 14.5 17.9 20.9 11.8 12.7 12.3 12.6 13.4 12.4 15.1 12.7 10.4 20.6 16.4 16.2 16.0 16.2 13.9 17.4 15.7 15.6 15.5 14.4 21.1 12.7 15.7 15.7 12.9 12.9 19.8 12.9 12.0 30.6 16.4 13.3 13.2 13.3 15.0 13.9 33.9 15.6 17.1 15.3 22.1 16.9 12.6 12.0 16.4 44.6 25.4 25.1 23.6 25.3 23.2 36.8 36.1 24.8 37.2 30.3 37.4 31.7 28.0 32.7 29.1 39.2 31.0 40.6 28.0 33.2 39.2 33.2 32.2 26.2 41.5 30.7 46.6 29.5 20.9 34.8 37.1 34.8 31.2 38.4 27.1 47.5 29.7 34.7 27.1 31.5 45.4 25.4 29.3 24.7 25.9 54.9 32.4 38.5 20.4 27.2 26.8 28.1 37.9 36.0 25.2 23.0 30.1 39.3 34.5 31.3 24.2 42.7 48.5 73.8 88.4 37.4 36.8 28.2 104.8 33.4 48.9 31.6 32.6 31.8 26.1 28.6 28.0 25.8 36.7 34.5 29.1 31.9 43.7 37.6 20.8 34.9 28.0 15.3 16.2 17.9 20.9 16.4 16.2 15.7 15.6 15.7 13.3 15.6 16.4 17.1 32.1 28.9 14.7 17.3 11.9 12.3 27.1 14.8 19.9 13.3 11.0 30.1 11.5 29.1 18.4 18.8 24.5 21.0 11.4 5.9 28.4 47.2 22.0 20.3 21.9 16.3 11.8 25.5 36.9 20.3 17.4 13.3 20.4 38.6 18.5 15.4 13.9 24.4 25.2 23.7 11.5 16.2 13.9 8.2 7.9 17.4 18.9 17.8 8.4 31.5 21.6 19.6 12.5 18.2 30.5 9.3 19.2 22.1 8.7 11.5 16.1 24.4 21.1 32.9 23.3 21.7 143.4 82.4 15.7 11.9 24.4 21.8 21.5 10.1 10.8 SLC4A9 AE4 ENSG00000113073 "Solute carrier family 4 member 9" Q96Q91 5 140360194-140375141 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 24 "kidney: 35.5" "Cell type enhanced" "Detected in some" "Distal tubular cells: 1.9;Excitatory neurons: 2.4;Inhibitory neurons: 2.4;Ionocytes: 2.0;Oligodendrocyte precursor cells: 1.5;Oligodendrocytes: 6.4;Spermatocytes: 1.7;Spermatogonia: 1.9" "Cancer enriched" "Detected in single" 8 "renal cancer: 0.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051307 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" Vesicles "HPA051307: AB_2681434" "unprognostic (1.68e-1)" "unprognostic (4.22e-2)" "unprognostic (2.20e-1)" "unprognostic (1.47e-1)" "unprognostic (1.10e-1)" "unprognostic (2.13e-1)" "unprognostic (1.02e-2)" "unprognostic (3.28e-3)" "unprognostic (2.78e-1)" "unprognostic (2.47e-1)" "unprognostic (4.78e-2)" "unprognostic (1.19e-1)" "unprognostic (4.24e-2)" "unprognostic (2.99e-2)" "unprognostic (3.06e-2)" "unprognostic (5.04e-2)" "unprognostic (1.82e-2)" 0.1 0.0 0.3 0.0 0.7 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.5 35.5 0.0 0.1 0.0 0.9 0.6 0.0 0.1 0.0 0.2 0.0 1.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.6 0.0 0.2 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.4 0.7 0.3 0.5 0.9 0.6 1.0 0.5 0.6 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.4 1.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 2.0 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.5 6.4 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.3 0.0 1.7 1.9 0.0 0.1 0.0 0.1 0.1 0.1 0.2 SLC51B OSTbeta ENSG00000186198 "Solute carrier family 51 subunit beta" Q86UW2 15 65045387-65053397 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 41.8;intestine: 107.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 354.6;Paneth cells: 145.1;Proximal enterocytes: 721.4" "Cancer enhanced" "Detected in many" "liver cancer: 9.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "CACO-2: 18.5;EFO-21: 11.9;Hep G2: 15.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008398, HPA008533" Enhanced Approved Vesicles,Mitochondria No NA "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" Mitochondria Vesicles "HPA008398: , HPA008533: AB_1854824" "unprognostic (6.18e-2)" "unprognostic (6.75e-3)" "unprognostic (1.66e-1)" "unprognostic (1.31e-2)" "unprognostic (5.88e-2)" "unprognostic (9.49e-2)" "unprognostic (9.77e-3)" "unprognostic (1.81e-2)" "unprognostic (3.35e-2)" "unprognostic (2.76e-1)" "unprognostic (2.24e-1)" "unprognostic (4.34e-2)" "prognostic favorable (8.46e-5)" "unprognostic (5.87e-2)" "unprognostic (2.64e-2)" "unprognostic (1.05e-2)" "unprognostic (1.17e-2)" 0.7 1.1 5.8 3.5 5.5 0.8 0.3 4.0 3.9 41.8 0.0 41.9 86.9 3.0 0.3 2.4 3.6 2.8 2.3 3.8 6.5 19.5 2.2 6.1 0.6 7.3 10.9 1.1 0.3 0.0 0.4 0.6 7.7 2.7 29.4 0.7 1.0 0.6 1.0 0.8 107.1 1.7 6.5 0.8 0.8 9.6 11.8 0.0 0.7 0.0 0.0 1.5 0.9 4.2 0.0 1.5 0.2 0.8 0.0 0.1 0.4 0.0 0.0 0.2 0.0 18.5 0.0 0.1 11.9 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.1 15.7 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 0.2 0.0 0.4 0.1 0.4 0.4 0.1 0.4 0.0 0.0 0.9 0.4 0.0 0.6 0.5 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.3 0.0 0.1 0.2 0.2 0.4 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 5.5 4.0 3.9 3.8 6.5 7.3 10.9 7.7 6.5 11.8 4.2 0.0 0.0 1.1 0.3 1.3 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 1.5 0.7 0.0 0.0 0.1 0.0 354.6 13.7 0.0 60.8 10.4 0.2 1.2 1.8 2.7 0.0 0.0 0.0 0.5 0.0 1.9 4.5 0.0 0.4 1.8 0.1 0.0 0.0 23.0 0.0 0.3 0.0 14.1 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 145.1 0.0 0.0 0.0 721.4 73.3 15.6 0.0 6.6 1.0 0.4 27.9 0.5 0.0 0.0 0.1 0.6 0.1 45.8 0.0 SLC66A1 "FLJ20320, LAAT-1, LAAT1, PQLC2" ENSG00000040487 "Solute carrier family 66 member 1" Q6ZP29 1 19312326-19329300 "Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 13 "Cytotrophoblasts: 26.9;Extravillous trophoblasts: 17.0;Hofbauer cells: 37.4;Syncytiotrophoblasts: 60.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057810 Approved Supported Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "HPA057810: AB_2683535" "unprognostic (7.84e-3)" "unprognostic (6.56e-2)" "unprognostic (6.54e-2)" "prognostic favorable (3.50e-4)" "unprognostic (3.77e-3)" "unprognostic (2.19e-1)" "prognostic unfavorable (2.64e-5)" "unprognostic (2.61e-1)" "unprognostic (4.47e-2)" "unprognostic (1.04e-1)" "unprognostic (1.42e-3)" "unprognostic (3.82e-2)" "unprognostic (4.70e-3)" "unprognostic (8.64e-2)" "unprognostic (2.07e-1)" "unprognostic (6.56e-2)" "unprognostic (4.46e-2)" 10.7 24.8 12.4 5.6 13.8 13.1 10.7 17.9 14.7 12.9 11.3 11.6 10.7 10.8 9.1 9.8 10.1 6.9 11.3 12.5 13.0 15.2 26.6 10.7 7.9 15.7 13.6 11.0 17.4 7.9 23.2 7.1 14.7 14.2 4.7 12.1 10.5 6.3 14.2 14.1 16.7 5.7 12.1 14.6 14.5 18.6 14.2 4.3 13.5 6.1 5.6 9.9 10.6 15.1 14.6 15.0 13.9 22.4 13.3 12.4 17.6 18.0 24.6 24.7 20.7 22.1 18.0 4.7 23.0 13.3 34.2 10.6 13.7 16.2 11.1 9.9 16.5 3.6 13.4 24.0 37.8 3.1 6.3 20.6 16.7 34.9 11.1 13.8 9.6 8.1 26.8 10.7 24.0 12.8 2.1 10.2 13.3 5.2 13.3 8.1 17.5 8.2 18.9 9.4 17.2 14.3 13.5 9.1 35.5 12.4 15.1 35.8 12.8 20.4 11.8 35.0 16.1 18.4 13.8 2.7 25.1 18.3 17.3 1.3 10.5 10.3 3.7 9.1 2.6 6.0 3.9 3.1 13.7 5.4 1.1 2.3 6.4 4.1 13.8 20.5 3.8 4.5 12.4 13.8 17.9 14.7 12.5 13.0 15.7 13.6 14.7 12.1 14.2 15.1 2.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 26.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 17.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 37.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 60.5 0.1 0.0 0.0 0.0 SLC6A11 GAT3 ENSG00000132164 "Solute carrier family 6 member 11" P48066 3 10816201-10940714 "Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 153.3" "Cell type enhanced" "Detected in some" "Astrocytes: 85.2;Excitatory neurons: 13.7;Inhibitory neurons: 25.8;Muller glia cells: 26.4;Oligodendrocyte precursor cells: 23.1" "Cancer enhanced" "Detected in many" "glioma: 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 5.2;HaCaT: 13.5;Hep G2: 16.0;hTCEpi: 11.9;NTERA-2: 6.7;T-47d: 5.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037981 Supported Supported Uncertain Nucleoplasm,Vesicles NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 64: Astrocytes - Nervous system maintenance" Nucleoplasm Vesicles "HPA037981: AB_10671383" "unprognostic (6.04e-2)" "unprognostic (8.01e-2)" "unprognostic (1.21e-7)" "unprognostic (8.60e-2)" "unprognostic (8.68e-2)" "unprognostic (9.72e-3)" "unprognostic (6.39e-3)" "unprognostic (9.77e-2)" "unprognostic (2.35e-1)" "unprognostic (3.92e-2)" "unprognostic (8.78e-2)" "unprognostic (1.51e-3)" "unprognostic (6.06e-2)" "unprognostic (4.44e-2)" "unprognostic (9.83e-2)" "unprognostic (2.31e-2)" 0.0 0.0 50.5 0.0 78.7 0.0 1.1 57.3 32.6 0.7 9.6 0.0 0.0 0.5 0.1 8.2 0.5 0.0 0.0 22.6 96.6 0.0 0.1 0.0 0.0 60.0 128.4 0.0 0.1 0.5 0.3 0.4 61.9 0.7 0.0 11.0 1.0 0.0 0.2 5.7 0.0 0.1 41.8 0.4 0.0 1.4 153.3 0.0 0.0 0.0 0.1 0.4 1.8 21.1 5.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 13.5 0.0 2.2 0.0 0.0 0.2 0.3 0.0 16.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.9 4.5 3.9 0.1 0.0 0.1 5.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.5 78.7 57.3 32.6 22.6 96.6 60.0 128.4 61.9 41.8 153.3 21.1 0.0 0.0 0.0 85.2 0.0 1.3 0.7 0.3 4.0 8.4 0.9 0.9 1.4 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 13.7 0.0 7.2 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 25.8 0.0 0.0 0.0 0.8 0.9 3.4 0.2 0.0 6.5 0.0 26.4 0.0 23.1 0.8 0.2 0.0 6.8 0.0 0.5 0.0 0.0 0.0 1.5 0.0 0.6 0.1 0.6 1.8 10.6 3.7 1.0 0.1 0.0 0.0 1.7 SLC6A12 BGT-1 ENSG00000111181 "Solute carrier family 6 member 12" P48065 12 190077-214570 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 35.2;kidney: 36.0;liver: 81.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 46.0;Hepatocytes: 22.7;monocytes: 10.7" "Cancer enhanced" "Detected in many" "liver cancer: 8.8;renal cancer: 11.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 50 "classical monocyte: 5.7;intermediate monocyte: 5.7;myeloid DC: 2.4;neutrophil: 3.0;non-classical monocyte: 7.9" "Group enriched" "Detected in many" 45 "dendritic cells: 2.4;granulocytes: 3.0;monocytes: 7.9" "Cell line enhanced" "Detected in some" "Hep G2: 7.2;RPTEC TERT1: 13.8;SuSa: 2.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034973 Approved Approved Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Vesicles "HPA034973: AB_10610427" "unprognostic (3.48e-1)" "unprognostic (4.73e-2)" "unprognostic (8.69e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (1.70e-1)" "unprognostic (1.09e-1)" "unprognostic (1.88e-2)" "unprognostic (8.30e-2)" "unprognostic (6.96e-3)" "unprognostic (2.70e-2)" "unprognostic (1.85e-2)" "unprognostic (3.68e-1)" "prognostic favorable (2.70e-6)" "unprognostic (2.30e-1)" "unprognostic (4.92e-4)" "unprognostic (3.35e-1)" "unprognostic (4.31e-4)" 0.2 0.4 22.6 1.1 23.3 0.1 0.4 18.0 35.2 0.8 12.4 0.7 4.5 1.1 6.8 0.0 3.4 1.0 0.3 18.5 21.5 36.0 81.5 2.4 0.5 19.8 25.2 0.3 1.6 0.4 0.8 0.5 20.9 0.1 1.8 0.5 0.1 0.0 0.1 0.2 0.8 0.9 16.5 0.5 2.4 1.6 22.4 0.3 6.3 0.0 0.3 0.4 0.3 17.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.8 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 7.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 13.8 0.1 0.0 0.4 0.0 0.0 0.1 2.9 0.2 0.4 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 5.7 0.0 0.0 5.7 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 3.0 0.0 7.9 0.0 0.0 1.9 22.6 23.3 18.0 35.2 18.5 21.5 19.8 25.2 20.9 16.5 22.4 17.7 0.1 0.0 0.5 4.2 0.6 0.1 0.0 0.0 0.0 0.5 0.9 0.6 0.7 0.0 0.1 46.0 0.0 0.0 0.0 1.6 1.9 0.0 4.6 3.5 1.7 0.2 0.0 0.0 0.4 0.4 0.0 0.6 2.0 8.8 0.0 0.1 0.7 22.7 2.4 0.0 0.3 1.7 0.0 1.9 2.5 6.2 0.6 1.6 0.0 8.4 10.7 5.2 0.0 0.5 9.2 0.0 1.2 0.0 0.0 0.0 0.0 8.0 0.0 0.4 6.6 0.6 0.4 2.3 4.5 0.0 0.4 0.8 0.1 0.1 1.0 0.1 SLC6A14 ENSG00000268104 "Solute carrier family 6 member 14" Q9UN76 X 116436606-116461458 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" Obesity "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 16.0;salivary gland: 20.6" "Group enriched" "Detected in some" 4 "Alveolar cells type 2: 115.7;Basal respiratory cells: 94.9;Club cells: 225.6;Pancreatic endocrine cells: 170.4;Respiratory ciliated cells: 58.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 1.7;Hep G2: 3.4;OE19: 1.2" HPA003193 Uncertain Approved Vesicles NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA003193: AB_2190122" "unprognostic (3.06e-2)" "unprognostic (3.55e-2)" "unprognostic (8.49e-2)" "unprognostic (1.00e-3)" "unprognostic (1.30e-3)" "unprognostic (1.49e-2)" "unprognostic (7.41e-3)" "unprognostic (3.67e-3)" "unprognostic (2.66e-1)" "unprognostic (1.83e-2)" "prognostic unfavorable (9.74e-4)" "unprognostic (1.34e-2)" "unprognostic (3.89e-2)" "unprognostic (2.08e-2)" "unprognostic (1.71e-1)" "unprognostic (1.59e-1)" 0.0 0.0 0.1 2.2 0.0 0.1 7.7 0.3 0.1 7.0 0.0 1.4 0.9 0.2 0.0 2.3 0.2 0.8 0.0 0.1 0.0 0.0 0.0 16.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.1 1.0 0.7 0.0 20.6 1.3 0.0 3.2 0.6 0.1 0.0 0.0 3.8 0.1 0.0 0.0 0.0 0.0 1.1 1.6 5.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.7 3.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 22.4 115.7 0.0 0.1 0.1 0.3 94.9 0.0 0.0 17.6 11.6 0.2 0.0 225.6 0.0 0.0 0.0 0.1 18.1 0.0 17.6 0.1 0.2 0.0 0.5 2.4 0.0 0.0 32.0 0.0 1.0 10.7 0.4 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 6.1 0.0 0.0 0.1 0.0 0.5 16.0 0.0 0.0 0.0 0.0 0.0 0.0 170.4 10.2 0.0 0.0 10.5 0.2 0.0 58.1 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.4 0.0 0.4 0.0 8.9 23.4 SLC6A15 "FLJ10316, hv7-3, NTT73, SBAT1, V7-3" ENSG00000072041 "Solute carrier family 6 member 15" Q9H2J7 12 84859491-84913629 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Neurotransmitter transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 21.9;retina: 15.7" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 42.1;Bipolar cells: 19.7;Excitatory neurons: 63.9;Inhibitory neurons: 57.4;Melanocytes: 32.0;Oligodendrocytes: 46.9" "Group enriched" "Detected in some" 4 "head and neck cancer: 2.2;melanoma: 7.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 93.5;ASC TERT1: 55.4;hTERT-HME1: 135.3;SCLC-21H: 91.7;SK-MEL-30: 71.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008609 Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoli Vesicles "HPA008609: AB_1857190" "unprognostic (1.01e-4)" "unprognostic (9.02e-2)" "unprognostic (1.27e-1)" "unprognostic (6.65e-6)" "unprognostic (1.25e-2)" "unprognostic (2.92e-1)" "unprognostic (7.65e-3)" "unprognostic (1.13e-1)" "unprognostic (1.97e-1)" "unprognostic (1.51e-1)" "unprognostic (4.05e-2)" "unprognostic (7.69e-4)" "unprognostic (2.57e-2)" "unprognostic (3.80e-1)" "unprognostic (1.23e-2)" "unprognostic (2.63e-3)" 0.6 1.4 8.0 0.2 7.8 0.0 0.4 4.0 12.7 0.9 0.0 0.4 0.1 0.5 0.0 2.8 0.2 0.0 0.0 6.9 12.9 0.2 0.0 0.1 0.0 7.4 21.9 0.3 0.0 0.0 5.5 3.8 16.7 0.2 0.2 15.7 0.8 0.1 0.0 1.4 0.4 0.3 0.2 0.0 0.1 0.4 8.8 0.1 0.3 1.6 0.2 0.2 1.3 5.0 0.0 2.5 10.3 0.0 93.5 55.4 0.1 0.1 21.0 1.5 1.0 0.0 0.0 0.0 0.0 0.2 12.0 1.2 0.0 23.7 0.1 0.0 25.1 0.0 4.1 0.0 33.5 0.0 0.2 31.4 48.2 11.9 135.3 25.3 0.3 0.0 0.0 0.0 25.9 0.0 0.1 0.0 28.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 91.7 22.6 0.1 31.1 71.0 0.2 0.0 0.0 0.0 12.7 6.5 0.1 0.0 0.0 0.0 0.1 23.1 0.0 27.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.0 7.8 4.0 12.7 6.9 12.9 7.4 21.9 16.7 0.2 8.8 5.0 0.0 0.0 0.0 4.2 0.1 2.7 0.0 3.1 42.1 19.7 0.1 0.1 0.5 0.0 0.0 0.0 6.2 0.3 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.2 0.0 0.0 63.9 0.0 0.6 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.8 57.4 0.0 0.0 0.0 0.4 0.6 0.0 0.0 32.0 1.9 0.0 1.1 0.0 4.0 46.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 11.1 0.0 0.5 1.0 0.4 0.5 5.8 0.6 0.3 0.0 0.0 0.0 0.0 SLC6A3 "DAT, DAT1" ENSG00000142319 "Solute carrier family 6 member 3" Q01959 5 1392794-1445440 "Disease related genes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant, Dystonia, FDA approved drug targets, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 73 "brain: 60.6" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 2.3;Cardiomyocytes: 1.2;Smooth muscle cells: 1.4" "Cancer enriched" "Detected in some" 18 "renal cancer: 25.7" "Region enriched" "Detected in some" 26 "midbrain: 60.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "midbrain: 80.6;thalamus: 29.0" "Region enriched" "Detected in some" 152 "midbrain: 302.6" "HPA012763, HPA013602, CAB016249, CAB078172" Enhanced Supported Approved Vesicles NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 43: Cardiomyocytes - Nuclear processes" Vesicles "CAB016249: AB_627402, CAB078172: AB_2665810, HPA012763: AB_2732405, HPA013602: AB_1847484" "unprognostic (2.25e-4)" "unprognostic (2.22e-1)" "unprognostic (8.45e-2)" "unprognostic (5.24e-2)" "unprognostic (7.75e-2)" "unprognostic (1.41e-2)" "unprognostic (4.64e-5)" "unprognostic (9.31e-2)" "unprognostic (7.89e-2)" "unprognostic (4.81e-2)" "unprognostic (1.30e-1)" "unprognostic (2.12e-2)" "prognostic unfavorable (3.40e-7)" "unprognostic (6.98e-2)" "unprognostic (1.64e-1)" "unprognostic (2.22e-2)" "unprognostic (4.74e-2)" 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.5 0.0 0.3 0.0 0.0 60.6 0.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 2.3 0.1 0.8 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 60.6 0.3 0.0 2.3 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 SLC6A4 "5-HTT, HTT, OCD1, SERT1" ENSG00000108576 "Solute carrier family 6 member 4" P31645 17 30194319-30236002 "FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 232.0" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 125.4;Proximal enterocytes: 100.9;Syncytiotrophoblasts: 106.4" "Cancer enhanced" "Detected in some" "breast cancer: 2.3" "Group enriched" "Detected in some" 11 "midbrain: 232.0;pons: 86.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.9;CACO-2: 3.9;Hep G2: 10.4" "Region enriched" "Detected in some" 4 "midbrain: 58.4" "Group enriched" "Detected in some" 7 "midbrain: 38.9;pons: 29.1" "HPA054723, HPA071354, HPA074728" Supported Supported Supported "Golgi apparatus,Vesicles" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus, Vesicles" "HPA054723: , HPA071354: , HPA074728: AB_2686708" "unprognostic (7.45e-2)" "unprognostic (7.13e-2)" "unprognostic (2.26e-1)" "unprognostic (3.72e-4)" "unprognostic (2.07e-1)" "unprognostic (8.42e-3)" "unprognostic (2.73e-2)" "unprognostic (3.39e-2)" "unprognostic (3.37e-3)" "unprognostic (1.17e-3)" "unprognostic (2.70e-3)" "unprognostic (1.16e-1)" "unprognostic (8.78e-2)" "unprognostic (4.98e-2)" "unprognostic (1.76e-1)" "unprognostic (4.05e-2)" "unprognostic (7.18e-2)" 0.1 0.1 0.1 0.0 0.0 0.2 0.2 0.3 0.2 0.2 0.0 0.5 10.3 0.0 0.0 2.8 1.7 0.0 0.9 0.1 0.2 0.2 0.0 28.8 0.1 14.8 232.0 0.1 1.4 0.2 0.0 18.4 86.1 0.1 0.1 0.1 0.7 0.2 0.1 0.5 40.3 0.0 0.0 0.1 0.9 0.3 0.2 0.0 0.5 0.0 0.2 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 10.4 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.4 0.5 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 0.2 0.1 0.2 14.8 232.0 86.1 0.0 0.2 0.2 1.1 16.0 5.0 0.3 0.0 0.1 0.4 0.1 17.1 1.2 0.1 0.0 1.0 0.0 1.9 1.8 0.0 125.4 1.5 0.2 0.0 0.0 2.8 0.2 0.6 3.2 0.0 0.0 0.9 0.0 8.6 1.3 0.0 0.5 2.5 0.2 2.2 0.3 9.5 0.0 0.6 2.3 0.0 1.0 1.2 2.2 0.3 5.9 0.0 0.0 0.1 0.5 2.1 0.5 0.5 0.4 0.0 0.4 0.1 0.3 100.9 0.4 0.7 0.8 0.0 1.3 0.5 0.5 0.9 4.8 0.3 106.4 0.5 0.2 4.1 0.3 SLC7A11 xCT ENSG00000151012 "Solute carrier family 7 member 11" Q9UPY5 4 138164097-138242349 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.5" "Cell type enhanced" "Detected in many" "Astrocytes: 368.6;Microglial cells: 148.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "hTCEpi: 84.2;TIME: 95.2;WM-115: 138.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064215 Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 17: WM-115 - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA064215: AB_2685213" "unprognostic (3.55e-3)" "unprognostic (4.64e-3)" "unprognostic (2.43e-2)" "unprognostic (7.18e-3)" "unprognostic (2.59e-1)" "unprognostic (8.80e-3)" "unprognostic (2.07e-8)" "unprognostic (1.98e-2)" "unprognostic (1.09e-2)" "prognostic favorable (1.77e-4)" "unprognostic (1.90e-2)" "unprognostic (4.07e-2)" "unprognostic (2.22e-8)" "unprognostic (3.81e-2)" "unprognostic (3.76e-2)" "unprognostic (2.29e-2)" "unprognostic (1.54e-2)" 0.2 0.1 18.8 2.2 17.5 1.0 0.4 16.5 16.5 0.9 7.2 0.7 0.4 0.3 6.7 2.6 4.5 1.6 1.7 16.2 26.5 0.1 0.2 1.7 0.4 24.3 22.8 0.5 2.7 0.3 0.8 0.7 19.0 0.6 1.0 4.2 0.7 0.1 0.0 0.6 0.4 0.1 19.8 0.4 4.9 0.8 20.1 0.3 4.6 0.0 0.8 2.7 0.5 20.1 5.2 42.1 18.4 14.5 3.9 5.0 5.1 23.2 15.9 5.2 11.8 4.7 17.7 9.7 29.5 80.8 27.6 6.7 10.0 19.8 21.7 18.5 2.1 6.9 37.7 10.7 59.6 18.1 6.3 11.9 84.2 14.6 64.6 7.6 65.1 9.6 9.5 24.4 27.3 3.7 2.5 1.7 3.6 25.1 11.9 2.8 6.1 11.5 3.1 20.1 7.6 1.5 10.1 2.9 35.4 3.9 4.4 38.1 95.2 6.7 18.8 10.2 18.3 20.5 10.3 9.7 11.4 9.7 138.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 18.8 17.5 16.5 16.5 16.2 26.5 24.3 22.8 19.0 19.8 20.1 20.1 0.5 0.0 8.4 368.6 2.5 4.6 7.5 8.8 1.8 7.3 2.2 1.3 5.4 1.5 8.1 0.0 2.1 3.6 28.5 7.9 0.0 4.4 3.2 3.2 2.3 27.8 27.0 0.8 12.5 25.1 0.7 5.7 65.2 18.3 4.5 1.0 2.9 0.4 0.6 1.7 7.3 19.8 22.4 0.3 63.5 0.8 2.5 18.3 5.4 148.9 51.7 47.9 0.0 12.1 8.6 30.4 1.5 2.2 4.1 58.5 0.4 0.1 7.3 2.0 0.0 2.1 4.0 1.1 0.7 1.9 3.1 1.1 0.9 7.0 4.2 37.6 SLC7A14 "KIAA1613, PPP1R142" ENSG00000013293 "Solute carrier family 7 member 14" Q8TBB6 3 170459548-170586075 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 15.9;pituitary gland: 7.3;retina: 6.1" "Group enriched" "Detected in some" 5 "Bipolar cells: 28.4;Excitatory neurons: 61.9;Horizontal cells: 28.6;Inhibitory neurons: 90.2;Oligodendrocytes: 67.4" "Group enriched" "Detected in some" 11 "glioma: 0.8;pancreatic cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "LHCN-M2: 3.2;SCLC-21H: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045929 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Cytosol" "Nucleoplasm, Plasma membrane" "HPA045929: AB_2679501" "unprognostic (1.00e-1)" "unprognostic (9.56e-2)" "unprognostic (1.03e-1)" "unprognostic (4.15e-2)" "unprognostic (1.43e-2)" "unprognostic (7.46e-2)" "unprognostic (9.16e-2)" "unprognostic (1.13e-1)" "unprognostic (1.29e-1)" "unprognostic (6.68e-3)" "unprognostic (6.36e-2)" "unprognostic (3.03e-6)" "unprognostic (1.54e-2)" "unprognostic (8.05e-2)" "unprognostic (1.71e-2)" "unprognostic (3.24e-3)" 0.0 2.3 8.9 0.4 8.1 0.1 0.0 5.5 8.8 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 7.9 15.9 0.1 0.0 0.0 0.0 15.6 6.4 0.1 0.7 0.0 7.3 0.0 14.9 0.1 0.4 6.1 0.0 0.0 0.1 0.1 0.3 0.1 4.0 0.0 0.2 0.1 8.9 0.0 0.0 0.0 0.0 0.0 0.1 7.7 0.0 0.0 0.1 0.0 0.5 0.9 0.0 0.3 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.5 0.3 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.9 8.1 5.5 8.8 7.9 15.9 15.6 6.4 14.9 4.0 8.9 7.7 0.8 3.2 2.2 4.6 0.1 0.4 0.3 0.1 0.0 28.4 0.1 0.0 1.0 0.0 2.5 0.0 2.1 0.1 0.1 0.0 0.0 0.0 0.6 0.2 0.2 0.5 1.8 0.0 61.9 0.0 0.1 0.4 0.0 0.1 2.5 0.1 0.4 0.9 0.0 28.6 90.2 0.1 0.0 0.0 1.2 0.6 2.1 0.4 3.6 6.5 0.0 1.8 0.0 9.5 67.4 0.1 1.2 2.6 0.1 0.3 0.1 0.2 3.0 4.3 0.0 0.7 0.5 0.0 0.2 0.0 0.6 0.0 0.4 0.1 0.0 0.2 SLC7A5 "CD98, D16S469E, E16, LAT1, MPE16" ENSG00000103257 "Solute carrier family 7 member 5" Q01650 16 87830023-87869507 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 110.7;brain: 121.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 178.7;Microglial cells: 109.6;Plasma cells: 135.1;Syncytiotrophoblasts: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 17.2" "Lineage enriched" "Detected in many" 10 "dendritic cells: 17.2" "Cell line enhanced" "Detected in all" "HBEC3-KT: 1326.5;hTCEpi: 2229.0;MCF7: 1264.6;SiHa: 1873.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052673, HPA056077" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA 51000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane, Cytosol" Vesicles "HPA052673: AB_2681909, HPA056077: AB_2683031" "unprognostic (2.71e-3)" "unprognostic (1.10e-2)" "unprognostic (1.02e-1)" "unprognostic (2.64e-1)" "unprognostic (3.22e-2)" "unprognostic (2.99e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (2.43e-4)" "unprognostic (6.86e-2)" "unprognostic (4.46e-2)" "unprognostic (1.27e-1)" "unprognostic (3.17e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.93e-2)" "unprognostic (5.52e-3)" "unprognostic (1.64e-2)" "unprognostic (7.19e-3)" 10.6 3.9 121.9 18.3 87.8 110.7 6.0 89.5 119.4 11.0 64.5 11.4 6.6 5.2 35.7 100.2 6.4 6.6 21.1 96.0 91.0 18.0 26.6 9.8 14.1 111.3 104.3 8.1 14.0 1.8 22.8 17.0 104.9 9.8 2.7 42.5 28.6 10.4 30.1 25.1 8.9 3.2 93.0 16.7 34.4 65.6 117.1 6.9 3.9 2.8 11.5 24.6 22.6 88.1 187.4 693.5 13.2 192.1 5.1 10.6 487.3 147.1 52.8 87.4 56.3 456.3 260.4 170.1 126.7 187.6 30.5 818.3 142.5 1326.5 61.0 179.9 71.9 140.3 618.0 331.2 199.5 131.2 246.0 35.9 2229.0 107.8 791.4 28.5 18.0 588.8 212.6 185.1 71.1 1264.6 159.2 192.7 63.3 116.7 166.0 152.0 52.4 264.1 98.3 15.7 109.2 43.5 1873.1 368.9 406.9 123.0 170.0 171.8 14.3 30.9 201.3 127.8 114.5 237.9 213.2 728.2 120.1 322.1 296.4 1.0 0.0 0.0 1.0 0.0 1.3 0.5 0.5 0.9 0.4 0.0 0.1 0.4 0.2 0.2 0.0 17.2 1.6 0.5 121.9 87.8 89.5 119.4 96.0 91.0 111.3 104.3 104.9 93.0 117.1 88.1 3.7 0.0 0.6 8.1 23.0 73.3 17.9 27.0 178.7 15.2 12.0 8.9 2.9 2.8 6.3 1.8 16.7 15.4 80.0 3.4 0.0 18.1 1.0 20.5 7.6 29.1 86.3 86.3 12.0 9.6 35.4 9.5 43.3 51.0 66.9 4.5 1.8 17.3 9.2 10.1 13.2 6.3 8.2 3.0 50.5 5.0 1.8 51.0 39.2 109.6 2.6 14.8 2.1 15.1 1.6 25.7 2.3 1.5 135.1 18.2 1.0 0.4 3.2 52.7 0.0 33.6 31.5 1.6 4.5 58.8 37.5 107.4 65.8 2.7 4.2 42.8 SLC7A6 "KIAA0245, LAT-2, LAT3, y+LAT-2" ENSG00000103064 "Solute carrier family 7 member 6" Q92536 16 68264516-68301823 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Antiport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 75.0" "Cell type enhanced" "Detected in many" "Microglial cells: 55.3;Syncytiotrophoblasts: 47.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050713 Uncertain Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Plasma membrane" "HPA050713: AB_2681218" "unprognostic (6.35e-2)" "unprognostic (4.63e-2)" "unprognostic (1.41e-1)" "unprognostic (1.40e-2)" "unprognostic (2.41e-1)" "unprognostic (5.02e-2)" "unprognostic (1.24e-3)" "unprognostic (1.16e-1)" "unprognostic (1.48e-1)" "unprognostic (5.16e-2)" "unprognostic (1.11e-1)" "unprognostic (2.76e-2)" "unprognostic (1.89e-3)" "unprognostic (7.82e-2)" "unprognostic (2.66e-1)" "unprognostic (4.79e-3)" "prognostic unfavorable (1.84e-4)" 35.3 8.8 1.7 15.5 1.9 8.4 26.9 6.5 3.3 5.5 17.3 8.3 3.9 5.8 11.5 4.5 8.6 4.4 18.5 3.3 2.2 5.9 2.0 10.9 18.6 1.0 1.3 2.7 3.8 2.5 9.6 18.6 1.5 6.2 11.1 5.0 7.3 5.2 75.0 10.2 12.0 7.7 1.0 10.7 6.6 5.1 2.2 37.6 16.7 26.9 21.5 6.8 4.8 1.1 22.6 22.1 16.3 16.8 46.9 27.6 42.9 24.9 18.7 36.9 30.6 97.9 16.2 43.7 19.8 33.4 10.9 33.1 32.0 32.2 39.7 9.5 22.9 23.8 47.3 31.0 7.7 28.2 20.3 19.3 26.1 27.5 13.5 11.4 25.3 21.0 35.1 7.3 20.5 11.7 36.4 19.3 12.4 14.6 8.1 45.0 10.2 36.0 12.0 19.6 23.7 13.5 75.7 20.8 6.8 13.4 30.9 13.3 38.4 24.6 19.0 20.5 32.8 16.7 33.5 50.3 15.6 20.1 17.2 3.4 3.2 2.8 4.3 1.7 5.4 6.8 6.6 4.3 3.6 6.3 11.7 6.7 6.1 7.1 1.4 16.8 3.1 1.5 1.7 1.9 6.5 3.3 3.3 2.2 1.0 1.3 1.5 1.0 2.2 1.1 8.5 41.7 18.8 12.4 18.4 19.6 9.3 8.5 13.6 6.1 5.9 4.8 19.9 2.8 4.9 18.4 37.5 25.1 23.3 7.3 0.0 3.3 5.5 10.7 16.8 12.0 2.4 2.1 39.3 4.0 2.5 12.8 4.1 3.3 4.5 1.8 6.8 1.4 14.6 10.1 40.3 10.5 4.1 8.5 12.1 18.3 5.9 9.9 10.6 55.3 10.0 1.8 14.4 13.0 10.7 5.6 5.9 3.8 16.0 8.0 2.5 0.6 10.4 2.7 0.0 10.8 7.2 17.3 10.9 6.7 21.9 47.9 23.5 4.3 7.8 2.6 SLC9A3R1 "EBP50, NHERF, NHERF1" ENSG00000109062 "SLC9A3 regulator 1" O14745 17 74748628-74769353 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Wnt signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 352.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 295.8;Proximal enterocytes: 536.9;Proximal tubular cells: 433.0;Squamous epithelial cells: 303.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 572.4;SK-BR-3: 450.7;T-47d: 873.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001962, HPA009672, HPA027247" Enhanced Approved "Vesicles,Plasma membrane,Centriolar satellite" NA Yes 940000 "Cluster 2: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "Vesicles, Centriolar satellite" "CAB001962: , HPA009672: AB_1857215, HPA027247: AB_10601162" "unprognostic (1.29e-1)" "unprognostic (4.58e-2)" "unprognostic (1.73e-2)" "unprognostic (5.51e-2)" "unprognostic (5.83e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (7.41e-2)" "unprognostic (5.61e-2)" "unprognostic (5.38e-2)" "unprognostic (7.53e-2)" "unprognostic (4.49e-2)" "unprognostic (1.56e-3)" "unprognostic (7.81e-3)" "unprognostic (5.53e-2)" "unprognostic (3.84e-2)" "unprognostic (2.08e-2)" 27.0 146.3 98.9 43.7 103.0 115.7 64.1 105.6 118.1 58.3 127.5 85.1 257.8 22.6 26.0 352.8 89.7 96.6 24.3 98.3 91.0 203.5 269.2 26.5 67.9 100.2 97.6 11.1 85.4 110.3 20.8 33.6 95.6 43.9 59.3 13.0 192.2 71.1 5.2 51.1 274.4 11.6 92.2 61.1 78.2 22.5 102.0 57.7 21.4 10.0 89.2 25.7 103.3 106.1 102.1 82.6 40.4 42.1 23.9 17.5 179.9 24.1 22.4 60.3 58.2 259.6 59.6 22.2 23.9 51.4 32.3 142.2 69.8 46.4 28.3 25.9 66.2 167.4 210.9 350.8 48.6 110.3 108.9 14.4 25.6 48.0 20.6 124.9 50.2 65.8 54.0 115.9 93.8 572.4 262.5 246.7 36.1 286.3 47.6 28.0 45.4 100.6 83.5 71.7 34.6 45.3 25.2 450.7 51.9 110.4 873.8 87.3 17.0 18.7 53.5 43.8 40.2 200.0 98.9 40.9 30.2 145.4 11.2 581.6 91.9 440.8 421.5 133.0 279.8 58.6 255.5 360.4 87.8 52.1 147.5 266.1 318.8 308.8 172.1 90.8 309.0 345.9 98.9 103.0 105.6 118.1 98.3 91.0 100.2 97.6 95.6 92.2 102.0 106.1 12.3 6.4 17.2 29.0 41.8 46.1 21.4 128.7 50.1 2.2 135.3 78.7 17.8 163.0 120.8 31.3 4.2 74.5 122.9 295.8 66.5 194.9 15.8 61.8 7.8 12.0 18.7 24.8 0.4 99.0 56.6 24.7 45.3 85.0 25.3 7.3 7.9 190.6 85.4 5.0 0.5 58.0 105.8 25.7 18.8 9.9 8.7 43.5 28.4 3.7 27.0 86.2 203.9 5.0 11.4 76.5 143.8 41.8 151.1 27.5 536.9 433.0 76.0 5.0 6.6 27.6 20.0 22.5 19.5 303.4 57.4 111.5 126.1 17.1 57.1 34.6 SLC9A6 "KIAA0267, NHE6" ENSG00000198689 "Solute carrier family 9 member A6" Q92581 X 135973841-136047269 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 40.3;Horizontal cells: 48.8;Inhibitory neurons: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059445, HPA059590" Enhanced Supported Vesicles NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 18: U-2197 - ECM organization" "Cluster 62: Horizontal cells - Visual perception" Vesicles "HPA059445: AB_2684021, HPA059590: AB_2684075" "unprognostic (1.35e-1)" "unprognostic (8.28e-3)" "unprognostic (4.36e-1)" "unprognostic (4.93e-2)" "unprognostic (1.84e-1)" "unprognostic (1.19e-1)" "unprognostic (2.60e-2)" "unprognostic (1.57e-1)" "unprognostic (1.15e-1)" "unprognostic (2.72e-2)" "unprognostic (7.43e-2)" "unprognostic (1.29e-1)" "unprognostic (7.07e-2)" "unprognostic (5.30e-2)" "unprognostic (1.75e-1)" "unprognostic (4.49e-2)" "unprognostic (5.06e-2)" 5.1 6.3 11.6 5.6 11.9 4.6 3.3 1.2 15.7 5.6 0.0 6.0 8.5 6.4 3.3 6.3 5.7 5.5 8.6 12.7 19.0 6.9 4.5 6.7 5.7 7.8 4.4 8.0 3.8 10.4 2.2 4.7 8.9 4.0 6.1 14.4 4.1 4.9 7.5 4.7 7.8 7.4 3.4 5.7 5.8 5.8 15.3 5.6 6.7 7.1 6.6 5.6 1.6 4.2 20.0 10.5 9.1 3.8 14.8 14.2 17.3 15.9 16.9 13.3 27.9 9.2 15.5 14.8 35.2 18.4 19.8 11.6 14.3 14.0 19.1 11.7 12.9 4.0 15.3 5.3 7.9 11.6 13.3 7.7 11.6 22.0 10.8 9.4 11.2 12.5 7.5 20.5 14.9 8.7 15.5 3.4 6.0 7.1 14.0 10.4 16.0 15.2 9.4 9.8 9.5 7.2 11.4 1.2 8.9 8.8 4.5 8.7 16.4 16.5 10.9 24.5 20.7 9.6 23.8 12.7 10.0 19.4 9.4 2.0 5.0 3.0 6.4 7.0 11.1 4.1 7.1 5.9 5.8 2.6 7.6 5.7 2.0 5.1 6.0 3.5 6.9 5.4 11.6 11.9 1.2 15.7 12.7 19.0 7.8 4.4 8.9 3.4 15.3 4.2 4.3 3.2 5.4 22.9 5.9 7.5 1.4 6.2 7.4 14.2 2.7 3.4 11.2 12.8 4.0 12.9 8.4 2.5 6.1 8.9 0.0 4.3 0.8 4.2 4.1 4.9 10.7 5.0 40.3 6.0 2.4 5.1 8.6 6.8 1.3 4.6 8.2 9.6 9.9 48.8 42.0 4.0 8.2 13.0 7.0 1.4 5.6 9.8 8.8 15.9 8.2 12.9 4.1 19.6 22.7 6.1 6.0 4.5 3.8 2.0 10.3 6.0 3.1 7.8 0.0 5.1 8.4 9.0 11.9 7.0 6.8 2.9 8.9 3.1 6.0 3.1 SLC9A7 NHE7 ENSG00000065923 "Solute carrier family 9 member A7" Q96T83 X 46599251-46759118 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Potassium transport, Sodium transport, Transport" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 41.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 43.3;Inhibitory neurons: 66.8;Oligodendrocyte precursor cells: 69.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048938, HPA075385" Approved Supported Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA048938: AB_2680565, HPA075385: AB_2686747" "unprognostic (2.77e-1)" "unprognostic (4.68e-2)" "unprognostic (1.37e-1)" "prognostic unfavorable (8.58e-4)" "prognostic unfavorable (8.14e-4)" "unprognostic (2.16e-2)" "unprognostic (2.73e-3)" "unprognostic (5.26e-3)" "unprognostic (1.28e-2)" "unprognostic (9.25e-2)" "unprognostic (5.30e-2)" "unprognostic (1.11e-1)" "unprognostic (2.08e-1)" "unprognostic (7.20e-2)" "unprognostic (2.62e-1)" "unprognostic (1.57e-1)" "unprognostic (1.13e-1)" 0.5 5.0 9.1 2.4 41.6 3.6 5.8 6.3 14.6 1.2 0.5 0.6 1.2 0.8 2.6 1.9 1.7 1.6 1.1 8.6 17.0 2.6 3.1 1.3 6.3 13.9 7.5 4.3 3.4 8.9 9.2 1.1 14.2 4.6 0.9 4.9 6.0 2.0 5.7 2.1 2.2 0.7 6.7 3.7 6.3 0.8 14.5 3.2 4.3 2.5 6.3 1.8 1.3 5.1 10.4 7.7 1.1 3.3 1.2 7.4 4.3 9.6 12.0 5.7 4.5 7.9 10.9 22.7 2.9 15.6 11.0 4.6 7.4 10.9 10.3 11.9 3.9 2.3 3.1 3.3 4.6 1.0 17.9 4.6 1.4 16.1 10.6 26.8 8.2 7.7 0.2 0.3 7.9 15.7 2.6 1.2 5.3 5.0 9.2 10.0 0.4 0.2 4.4 11.4 8.2 1.0 4.9 7.3 2.1 9.2 9.7 0.4 0.4 12.0 4.0 1.8 5.7 2.3 0.5 11.2 17.1 0.1 4.0 0.5 0.2 0.1 0.1 0.2 0.1 1.7 0.2 0.1 1.1 1.7 0.1 0.1 0.8 0.5 0.2 2.8 0.3 0.2 9.1 41.6 6.3 14.6 8.6 17.0 13.9 7.5 14.2 6.7 14.5 5.1 0.5 3.2 8.2 11.4 21.0 0.6 10.1 0.9 1.2 13.0 16.9 8.6 5.7 1.5 2.6 16.5 4.2 7.9 24.4 0.3 0.0 17.6 0.0 1.8 2.0 1.5 2.4 5.5 43.3 14.2 0.7 2.7 13.3 1.7 0.0 4.5 0.7 6.5 6.4 13.5 66.8 2.0 0.0 6.3 8.4 0.6 0.9 9.2 1.8 3.7 8.0 6.1 1.0 69.9 1.6 16.4 0.1 0.4 2.8 21.0 0.1 2.1 0.1 3.5 6.6 12.1 1.9 0.0 1.6 4.2 1.0 7.3 2.9 1.3 0.9 11.5 SLCO5A1 "OATP-J, OATP5A1, OATPRP4, SLC21A15" ENSG00000137571 "Solute carrier organic anion transporter family member 5A1" Q9H2Y9 8 69667046-69834978 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.5;skeletal muscle: 7.6;tongue: 11.1" "Group enriched" "Detected in many" 4 "Bipolar cells: 10.1;Cardiomyocytes: 14.4;Enteroendocrine cells: 15.6;Excitatory neurons: 8.6;Inhibitory neurons: 30.1;monocytes: 21.2;Oligodendrocyte precursor cells: 26.2;Plasma cells: 14.3;Prostatic glandular cells: 11.8" "Cancer enhanced" "Detected in some" "prostate cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 5.5;NTERA-2: 3.7;RPMI-8226: 3.6;SCLC-21H: 3.9;U-266/70: 2.1" "Group enriched" "Detected in some" 7 "basal ganglia: 2.3;olfactory bulb: 6.7" "Region enriched" "Detected in some" 7 "olfactory bulb: 12.8" HPA025062 Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Vesicles "HPA025062: AB_1857220" "unprognostic (1.30e-3)" "unprognostic (7.35e-3)" "unprognostic (4.13e-2)" "unprognostic (1.14e-2)" "unprognostic (1.48e-1)" "unprognostic (5.70e-2)" "unprognostic (1.46e-2)" "unprognostic (1.51e-1)" "unprognostic (2.37e-4)" "unprognostic (1.75e-1)" "unprognostic (4.48e-4)" "unprognostic (1.74e-2)" "unprognostic (2.92e-6)" "unprognostic (2.20e-1)" "unprognostic (1.23e-1)" "unprognostic (2.13e-1)" "unprognostic (4.50e-2)" 0.1 0.0 0.3 0.9 0.4 0.9 0.1 0.0 0.4 0.2 0.0 0.2 0.2 0.2 0.0 0.5 0.3 0.2 3.7 0.2 0.6 0.0 0.0 0.1 1.0 0.2 0.0 0.0 0.4 0.0 1.5 0.0 0.2 2.3 0.4 0.7 0.3 0.0 7.6 0.1 0.3 0.1 0.0 0.5 0.2 0.3 0.1 6.5 0.0 11.1 0.9 0.6 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 1.5 1.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.7 3.7 0.0 0.6 0.6 0.6 3.6 0.0 0.0 3.9 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 2.1 0.3 0.0 0.2 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.4 0.2 0.6 0.2 0.0 0.2 0.0 0.1 0.1 0.1 3.2 0.0 3.6 3.6 0.3 1.8 0.0 0.6 10.1 0.2 0.3 14.4 0.0 0.6 0.0 2.1 0.0 0.0 0.6 0.0 1.8 0.6 0.4 1.7 2.0 15.6 0.0 8.6 1.3 0.0 4.0 0.0 1.7 0.0 0.0 0.0 0.2 0.1 1.7 30.1 2.0 0.0 0.0 3.6 0.6 0.0 0.7 0.0 3.7 21.2 0.5 0.0 26.2 2.2 2.1 0.1 0.0 14.3 11.8 0.0 0.1 0.0 0.3 0.0 3.4 2.0 1.1 2.6 0.4 0.4 0.0 0.1 0.4 1.5 1.5 SLF2 "C10orf6, FAM178A, FLJ10512, FLJ25012" ENSG00000119906 "SMC5-SMC6 complex localization factor 2" Q8IX21 10 100912963-100965134 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Leydig cells: 108.1;Peritubular cells: 105.7;Theca cells: 77.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 145.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038499, HPA057568" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 68: Epididymis - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Vesicles" "HPA038499: AB_10672520, HPA057568: AB_2683471" "unprognostic (9.05e-2)" "unprognostic (1.18e-2)" "unprognostic (3.89e-2)" "unprognostic (4.54e-2)" "unprognostic (1.13e-1)" "unprognostic (6.19e-3)" "unprognostic (2.16e-2)" "unprognostic (7.87e-2)" "unprognostic (2.02e-1)" "unprognostic (1.30e-1)" "unprognostic (2.66e-2)" "unprognostic (1.54e-2)" "unprognostic (1.16e-3)" "unprognostic (2.85e-1)" "unprognostic (4.90e-2)" "unprognostic (1.39e-1)" "unprognostic (2.41e-1)" 9.1 17.2 17.3 10.9 29.2 11.8 8.8 20.4 23.1 14.0 9.3 12.6 7.9 20.8 48.6 8.9 17.6 8.0 10.8 17.0 24.9 11.3 11.6 10.8 14.7 24.5 24.7 25.1 13.1 7.9 23.8 15.4 25.7 15.2 10.1 11.7 9.4 12.9 17.8 13.4 12.7 10.7 19.1 23.1 10.4 25.8 25.3 12.2 11.3 13.3 11.5 11.3 11.2 46.2 25.7 20.6 29.6 31.4 16.1 20.9 11.3 26.3 18.5 24.1 29.0 15.2 17.5 24.1 15.8 11.3 17.9 25.3 20.4 8.8 29.1 26.6 16.6 21.7 14.2 31.0 11.7 28.0 24.9 10.0 13.2 18.6 19.9 25.1 15.7 14.7 15.6 22.5 37.3 17.7 19.1 16.0 13.7 9.9 15.2 18.5 145.7 8.3 10.1 12.8 6.6 12.9 16.5 4.6 30.6 14.1 26.3 10.7 20.6 28.2 23.4 18.0 31.1 18.1 28.5 19.1 20.0 32.9 15.1 6.1 6.6 7.0 9.8 6.7 8.9 8.6 7.8 8.5 5.2 11.0 8.5 7.8 3.6 9.1 7.5 7.5 8.0 4.6 17.3 29.2 20.4 23.1 17.0 24.9 24.5 24.7 25.7 19.1 25.3 46.2 18.4 25.6 18.9 0.0 18.2 0.0 8.4 0.0 12.5 33.8 13.8 12.6 0.0 5.7 8.6 25.8 25.0 17.4 29.4 9.0 13.7 11.0 8.4 22.7 64.8 20.8 12.2 11.3 0.0 8.0 7.1 20.2 10.7 25.0 24.0 32.3 26.7 12.8 17.9 38.7 0.0 10.5 0.0 18.2 0.0 10.4 108.1 18.6 0.0 0.0 19.2 19.7 46.4 0.0 0.0 7.0 8.4 105.7 12.3 9.4 9.3 8.9 13.8 31.4 19.7 44.5 12.8 33.5 43.0 10.4 0.0 5.1 19.7 77.6 8.2 6.0 SLFN5 MGC19764 ENSG00000166750 "Schlafen family member 5" Q08AF3 17 35243071-35273655 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 261.6;Respiratory ciliated cells: 133.0;T-cells: 128.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 24.7;MAIT T-cell: 30.6;memory CD4 T-cell: 30.7;memory CD8 T-cell: 28.9;naive CD4 T-cell: 37.5;naive CD8 T-cell: 31.2;NK-cell: 42.3;T-reg: 68.8" "Group enriched" "Detected in all" 7 "NK-cells: 42.3;T-cells: 68.8" "Cell line enhanced" "Detected in many" "HHSteC: 108.6;hTERT-HME1: 146.8" "Low region specificity" "Detected in all" HPA017760 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm Vesicles "HPA017760: AB_2189993" "unprognostic (3.43e-1)" "unprognostic (3.26e-1)" "unprognostic (4.66e-2)" "unprognostic (1.60e-1)" "unprognostic (8.35e-2)" "unprognostic (1.15e-3)" "unprognostic (1.70e-2)" "unprognostic (2.29e-1)" "unprognostic (2.81e-1)" "unprognostic (7.01e-2)" "unprognostic (2.41e-3)" "unprognostic (2.39e-1)" "unprognostic (6.05e-3)" "unprognostic (3.27e-1)" "unprognostic (7.77e-2)" "unprognostic (3.92e-1)" "unprognostic (1.48e-1)" 17.8 8.7 2.7 23.9 2.5 5.4 11.6 2.1 2.5 20.0 3.8 6.4 7.0 14.1 3.4 8.9 14.0 12.1 8.6 2.6 3.5 5.0 5.8 21.1 32.4 6.1 2.2 5.6 3.7 6.7 1.5 14.1 4.9 10.3 7.8 2.3 18.0 15.7 20.7 5.0 8.0 11.5 4.9 25.8 9.9 2.0 3.5 40.9 11.5 10.1 28.2 19.9 5.2 5.7 21.3 10.7 1.7 1.8 30.2 52.2 4.2 54.3 85.4 44.5 49.2 0.2 13.5 2.7 34.1 54.0 11.8 87.1 1.0 24.5 30.9 0.7 1.9 0.4 11.6 1.3 108.6 1.6 0.6 59.9 60.5 34.0 146.8 26.8 20.6 22.0 0.2 31.1 31.4 1.7 26.9 1.3 1.7 4.7 8.0 0.0 17.9 0.2 11.6 51.8 3.6 0.0 6.0 5.6 93.7 6.0 35.9 0.8 81.2 17.6 6.8 12.9 12.5 6.0 0.6 0.4 51.9 0.3 26.0 6.3 4.3 2.9 24.7 6.4 30.6 0.9 30.7 28.9 3.6 1.6 37.5 31.2 1.8 42.3 7.8 1.2 68.8 18.2 2.7 2.5 2.1 2.5 2.6 3.5 6.1 2.2 4.9 4.9 3.5 5.7 126.9 60.9 71.7 1.6 8.4 4.6 27.1 97.8 8.0 1.6 16.5 15.9 10.1 28.6 92.3 18.4 0.0 0.3 75.6 1.8 1.9 71.7 1.9 95.0 23.2 90.4 1.2 3.6 4.1 38.8 5.3 30.3 18.8 56.0 61.3 1.4 79.2 4.7 13.2 6.7 3.6 4.6 46.8 26.5 14.4 0.4 7.5 22.6 12.4 12.2 49.1 6.7 261.6 3.0 10.1 70.0 3.8 1.5 17.6 122.5 1.7 1.9 133.0 4.2 13.1 34.9 29.8 0.5 1.9 10.2 4.0 0.3 128.6 5.4 1.0 74.2 SLITRK5 "bA364G4.2, KIAA0918, LRRC11" ENSG00000165300 "SLIT and NTRK like family member 5" O94991 13 87672615-87696272 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.6;fallopian tube: 2.9;salivary gland: 3.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 9.7;Excitatory neurons: 20.4;Horizontal cells: 21.9;Inhibitory neurons: 13.3;Oligodendrocyte precursor cells: 11.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.0;HeLa: 3.7;hTERT-RPE1: 3.2;U-138 MG: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013843, HPA073230" Uncertain Approved Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 12: NES - Nervous system development" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA013843: AB_1857233, HPA073230: " "unprognostic (1.92e-1)" "unprognostic (1.01e-2)" "unprognostic (3.82e-1)" "unprognostic (7.11e-4)" "unprognostic (6.94e-2)" "unprognostic (8.57e-3)" "unprognostic (1.63e-1)" "unprognostic (8.58e-3)" "unprognostic (1.18e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-2)" "unprognostic (1.11e-1)" "unprognostic (2.10e-2)" "unprognostic (1.81e-2)" "unprognostic (2.82e-1)" "unprognostic (1.36e-2)" "unprognostic (1.60e-1)" 0.1 0.1 1.3 0.0 1.9 0.0 0.1 0.8 2.6 0.1 0.0 0.3 0.0 0.0 0.4 0.1 2.9 0.0 0.1 1.9 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.2 0.0 0.0 0.7 0.1 0.7 3.7 1.3 0.1 0.1 0.0 0.0 0.2 0.0 0.2 0.1 1.5 0.0 0.9 0.1 0.1 0.0 0.5 1.1 0.0 0.7 7.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.0 1.3 0.9 3.7 0.0 0.4 0.0 0.0 1.5 0.1 0.0 0.6 3.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.7 0.0 0.9 0.7 0.1 0.1 0.2 0.0 1.1 0.1 0.0 0.2 0.0 0.0 0.5 1.7 0.0 2.4 0.0 0.0 0.4 1.1 0.0 0.0 2.1 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 1.3 1.9 0.8 2.6 1.9 0.6 0.0 0.1 0.0 0.2 1.5 1.1 0.0 0.0 1.1 1.3 0.0 0.1 1.5 0.0 0.0 9.7 0.6 1.7 1.8 1.5 0.0 0.0 4.2 0.0 5.9 0.2 0.0 0.4 0.7 2.1 0.5 1.0 0.0 2.7 20.4 0.0 0.0 1.6 0.0 5.0 1.3 0.5 0.0 0.0 0.0 21.9 13.3 1.9 0.0 0.0 0.0 1.0 5.9 0.5 0.0 1.0 0.1 7.0 0.0 11.1 0.9 0.0 0.1 4.9 0.0 2.5 0.0 0.1 1.5 1.6 0.0 4.6 0.3 5.5 0.2 0.4 0.0 0.0 0.1 0.0 0.2 1.1 SMARCA1 "hSNF2L, ISWI, NURF140, SNF2L, SNF2L1, SNF2LB, SWI" ENSG00000102038 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1" P28370 X 129446501-129523500 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Leydig cells: 142.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003335, HPA064712" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 36: Stromal cells - Cell proliferation" Nucleoplasm Vesicles "HPA003335: AB_1080024, HPA064712: AB_2685332" "unprognostic (1.40e-1)" "unprognostic (8.28e-3)" "unprognostic (2.30e-1)" "unprognostic (5.06e-2)" "unprognostic (6.21e-2)" "unprognostic (2.16e-2)" "unprognostic (5.44e-2)" "unprognostic (7.15e-2)" "unprognostic (3.41e-2)" "unprognostic (1.53e-1)" "prognostic favorable (3.03e-4)" "unprognostic (9.26e-2)" "prognostic favorable (5.09e-4)" "unprognostic (1.87e-3)" "unprognostic (1.28e-1)" "unprognostic (6.14e-2)" "unprognostic (2.33e-2)" 19.0 78.6 15.7 9.0 17.8 0.3 20.6 14.0 18.1 27.9 36.0 20.9 6.7 27.2 34.7 11.3 20.1 21.4 24.5 19.9 31.6 23.9 62.1 16.3 4.6 17.0 19.0 72.6 15.8 44.6 34.8 38.0 20.3 36.7 7.0 26.7 18.5 35.4 17.3 8.1 8.4 25.9 17.1 8.9 17.3 57.7 26.7 7.9 45.3 19.8 4.2 30.0 14.0 18.1 23.5 53.5 104.8 67.9 76.3 67.1 36.6 46.8 133.2 68.6 76.7 18.3 80.9 0.0 71.8 88.7 81.1 22.1 66.6 27.5 76.4 0.1 12.9 0.2 46.9 100.0 32.6 0.0 0.1 84.2 7.8 49.0 9.3 104.3 50.4 13.1 12.4 5.7 76.1 0.0 0.6 0.2 42.6 9.0 31.0 0.0 56.7 0.2 67.4 28.3 26.0 69.8 6.6 0.9 12.1 73.1 46.9 0.6 35.7 46.0 23.3 30.3 26.4 0.0 0.0 0.2 40.7 0.0 28.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.5 0.0 0.2 0.0 0.1 15.7 17.8 14.0 18.1 19.9 31.6 17.0 19.0 20.3 17.1 26.7 18.1 23.2 96.1 55.0 24.2 1.5 23.3 35.4 28.3 47.3 26.5 34.8 24.1 80.5 12.8 47.6 40.5 45.9 56.9 1.8 0.1 29.4 30.1 3.7 32.2 80.2 25.6 16.8 3.2 29.3 12.0 15.7 64.3 23.4 42.7 2.5 84.3 22.9 67.0 15.0 92.5 43.4 2.6 14.2 3.2 9.9 18.4 142.9 3.0 28.4 22.5 5.7 47.7 0.0 41.2 17.2 14.0 0.1 125.6 0.1 24.9 0.2 34.9 41.0 13.4 65.7 40.0 49.7 11.4 23.9 17.5 11.8 58.4 2.0 82.9 2.3 29.2 SMARCA2 "BAF190, BRM, hBRM, hSNF2a, SNF2, SNF2L2, SNF2LA, Sth1p, SWI2" ENSG00000080503 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2" P51531 9 1980290-2193624 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Helicase, Hydrolase" "Disease variant, Hypotrichosis, Mental retardation, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 246.5;Inhibitory neurons: 263.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 6 "HDLM-2: 1486.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029981, CAB037276" Enhanced Approved "Nucleoplasm,Vesicles,Intermediate filaments" NA NA 19000 "Cluster 6: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" "Intermediate filaments" "CAB037276: AB_477083, HPA029981: AB_10602406" "unprognostic (5.34e-2)" "unprognostic (1.99e-2)" "unprognostic (6.27e-2)" "unprognostic (6.53e-2)" "unprognostic (1.28e-1)" "unprognostic (1.13e-2)" "unprognostic (4.91e-2)" "unprognostic (2.80e-2)" "unprognostic (2.62e-1)" "unprognostic (3.97e-1)" "unprognostic (3.60e-3)" "unprognostic (9.64e-2)" "prognostic favorable (1.26e-6)" "unprognostic (3.09e-1)" "unprognostic (2.81e-1)" "unprognostic (8.32e-3)" "unprognostic (8.50e-2)" 51.9 55.9 68.9 36.1 73.9 95.7 62.0 87.4 81.7 42.1 40.2 31.0 20.2 53.2 57.3 41.7 57.4 46.0 43.8 60.3 53.7 45.9 58.3 40.3 50.9 43.2 54.4 166.0 36.8 170.3 32.7 48.2 50.6 42.5 31.7 63.6 50.7 53.2 97.7 48.2 27.7 44.2 40.3 52.3 32.0 56.3 55.7 42.2 55.7 60.1 47.8 31.8 28.8 52.9 45.7 32.9 23.7 33.8 47.2 56.6 71.7 59.4 44.6 24.9 19.5 0.5 17.7 76.2 22.0 50.7 13.5 18.8 12.9 46.5 17.6 1486.7 20.2 208.3 88.2 16.2 18.7 88.3 118.1 37.6 17.5 24.9 46.4 44.9 40.3 35.4 7.3 255.1 43.0 19.1 22.2 72.3 23.4 26.4 12.6 97.6 30.5 69.4 57.6 40.9 15.3 14.0 36.2 8.3 14.9 34.1 16.3 55.8 49.1 40.6 19.8 25.8 27.3 22.9 31.8 33.6 43.5 32.5 11.4 26.1 5.2 15.8 10.8 7.2 10.4 12.3 10.5 11.2 6.4 9.4 13.1 10.3 14.6 9.9 10.3 12.5 12.6 5.0 68.9 73.9 87.4 81.7 60.3 53.7 43.2 54.4 50.6 40.3 55.7 52.9 83.9 73.7 70.6 246.5 57.2 58.6 18.3 55.0 82.6 57.6 103.7 74.3 95.2 31.5 54.1 106.7 37.5 99.3 102.8 32.0 31.3 30.6 38.0 44.1 61.6 69.0 37.2 41.2 216.2 22.4 24.5 65.7 19.4 45.2 48.0 27.9 36.8 62.0 31.5 35.3 263.2 31.2 48.8 54.9 34.7 22.6 76.7 57.5 49.8 142.4 45.2 53.4 43.3 120.6 100.8 18.7 15.1 86.9 71.4 13.9 26.9 18.5 88.3 37.4 13.1 58.7 40.3 42.9 14.6 66.2 52.7 88.7 74.8 56.1 28.2 12.7 SMARCD1 "BAF60A, CRACD1, Rsc6p" ENSG00000066117 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1" Q96GM5 12 50085200-50100707 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Chromatin regulator" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004101 Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" Nucleoplasm Vesicles "HPA004101: AB_1080026" "unprognostic (1.88e-1)" "unprognostic (1.89e-1)" "unprognostic (1.51e-1)" "unprognostic (2.11e-2)" "unprognostic (1.02e-1)" "unprognostic (2.76e-1)" "prognostic unfavorable (2.53e-8)" "unprognostic (3.62e-2)" "unprognostic (1.44e-1)" "unprognostic (4.23e-2)" "unprognostic (1.16e-2)" "unprognostic (2.10e-2)" "unprognostic (1.20e-3)" "unprognostic (2.18e-1)" "unprognostic (3.45e-1)" "unprognostic (1.38e-1)" "unprognostic (5.04e-2)" 25.8 28.1 25.2 23.2 27.6 44.0 24.9 24.4 27.0 23.5 20.8 22.0 23.2 27.9 27.1 27.5 23.8 17.9 18.3 26.3 23.8 25.3 19.0 23.9 35.0 25.7 25.7 26.4 22.5 47.3 19.7 28.9 25.3 23.2 27.2 25.1 24.3 21.8 16.9 24.3 27.8 28.8 24.8 31.3 20.5 23.8 25.8 57.2 26.8 16.1 47.6 23.5 21.7 27.6 28.4 47.6 134.8 75.8 41.1 38.9 68.1 35.1 62.0 100.3 58.2 130.0 42.1 109.4 51.0 67.2 44.4 35.4 112.9 91.5 87.3 84.4 87.0 107.2 49.4 75.8 49.3 95.0 41.1 40.2 60.2 59.8 107.4 66.1 119.5 114.0 93.1 64.8 50.6 67.7 137.6 54.0 166.0 43.2 76.6 165.5 34.9 96.0 57.3 66.1 71.4 121.3 73.1 35.2 139.3 100.4 79.4 78.7 70.4 50.1 56.0 31.7 69.9 91.6 88.2 95.4 40.6 37.7 56.9 3.4 1.2 2.2 2.9 1.2 2.9 3.6 1.6 2.0 1.8 2.7 1.0 3.3 0.5 1.7 1.9 3.5 2.7 1.2 25.2 27.6 24.4 27.0 26.3 23.8 25.7 25.7 25.3 24.8 25.8 27.6 29.7 0.0 9.6 11.1 42.9 16.6 22.3 17.7 42.7 33.7 33.2 30.2 6.5 15.7 20.5 27.6 20.9 21.1 39.6 21.6 52.8 32.8 4.3 20.0 36.9 30.1 31.1 25.7 9.3 29.0 19.4 17.8 14.8 30.5 16.5 40.0 17.5 15.1 17.3 26.9 10.5 18.2 10.2 14.4 13.1 9.1 16.4 16.8 17.8 7.5 27.1 26.5 29.9 11.1 17.1 36.8 14.8 16.1 28.9 28.8 19.5 47.9 9.4 28.8 32.9 31.6 28.2 28.4 36.5 31.3 19.6 11.1 30.0 26.8 19.1 15.9 SMIM17 ENSG00000268182 "Small integral membrane protein 17" P0DL12 19 56643159-56657247 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 8.9" "Group enriched" "Detected in some" 5 "Excitatory neurons: 18.0;Inhibitory neurons: 32.7" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.0;HEK 293: 1.8;SCLC-21H: 1.7" "Low region specificity" "Detected in all" "HPA071857, HPA071861" Enhanced Approved Vesicles NA NA "Cluster 65: Brain - Ion transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA071857: AB_2686461, HPA071861: AB_2686462" "unprognostic (1.32e-1)" "unprognostic (2.82e-1)" "unprognostic (1.24e-1)" "unprognostic (5.67e-3)" "unprognostic (1.62e-1)" "unprognostic (4.57e-2)" "unprognostic (5.84e-2)" "unprognostic (3.00e-2)" "unprognostic (2.51e-1)" "unprognostic (6.50e-2)" "unprognostic (4.64e-2)" "unprognostic (9.02e-3)" "unprognostic (3.46e-3)" "unprognostic (6.26e-2)" "unprognostic (1.01e-1)" "unprognostic (3.71e-3)" "unprognostic (7.51e-3)" 0.4 0.3 6.0 0.2 4.9 0.2 0.6 3.7 8.9 0.4 0.0 0.7 0.3 0.6 1.3 0.3 0.5 0.2 0.4 6.4 8.9 0.3 0.2 0.3 0.2 6.9 6.7 0.5 0.3 0.1 1.6 0.2 8.2 0.4 0.3 2.7 0.4 1.0 0.5 0.7 0.2 0.4 3.3 0.3 0.3 0.4 7.5 0.3 0.3 0.2 0.2 0.4 0.3 2.8 0.1 0.0 2.0 0.5 0.3 0.2 0.5 0.2 0.1 0.4 0.1 0.0 0.1 0.2 0.3 0.2 0.2 0.1 0.3 0.3 0.2 0.1 1.8 1.1 0.4 0.4 0.3 1.0 0.3 0.3 0.3 0.1 0.3 0.3 0.2 1.1 0.1 0.0 0.5 0.0 1.3 0.3 0.1 0.0 0.3 0.7 1.2 0.1 0.1 0.0 1.7 0.3 0.6 0.1 0.3 0.3 0.0 0.4 0.4 0.6 0.1 0.2 0.1 0.1 0.3 0.5 0.3 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 4.9 3.7 8.9 6.4 8.9 6.9 6.7 8.2 3.3 7.5 2.8 0.3 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 32.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.4 0.0 3.5 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SMIM3 "C5orf62, MSTP150, NID67" ENSG00000256235 "Small integral membrane protein 3" Q9BZL3 5 150778757-150796734 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 161.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 85.5;Basal squamous epithelial cells: 80.8;granulocytes: 90.0;Macrophages: 79.3;Sertoli cells: 138.1;Smooth muscle cells: 77.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 409.9;ASC TERT1: 200.1;LHCN-M2: 193.8;U-87 MG: 291.5" "Low region specificity" "Detected in all" HPA075345 Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA075345: AB_2686744" "unprognostic (2.33e-1)" "unprognostic (4.05e-2)" "unprognostic (1.35e-2)" "unprognostic (2.70e-2)" "unprognostic (9.45e-2)" "unprognostic (5.65e-2)" "unprognostic (4.57e-3)" "unprognostic (1.47e-1)" "unprognostic (3.90e-1)" "unprognostic (2.05e-2)" "unprognostic (9.71e-3)" "unprognostic (3.46e-3)" "prognostic unfavorable (1.15e-8)" "unprognostic (3.87e-3)" "unprognostic (1.31e-2)" "unprognostic (2.16e-1)" "unprognostic (1.46e-3)" 161.0 36.2 20.5 25.5 20.3 89.5 71.5 20.9 26.4 21.9 42.1 26.8 13.4 16.2 22.6 16.8 30.2 25.7 36.8 20.5 22.1 34.9 12.2 30.9 11.7 23.3 21.5 25.9 33.7 26.9 15.1 46.0 23.6 27.6 19.1 20.4 14.0 24.1 15.0 12.5 23.0 28.3 20.7 25.2 21.6 4.1 23.5 17.7 21.0 15.5 8.8 29.0 18.7 19.6 13.8 4.5 7.3 60.8 409.9 200.1 15.9 52.3 114.6 19.2 77.2 21.5 35.3 0.0 3.1 55.1 12.7 10.7 12.5 11.8 28.6 0.2 3.8 20.0 2.8 9.9 72.4 19.7 130.0 167.9 23.6 54.2 25.1 122.3 6.4 46.6 5.5 0.4 193.8 10.5 28.5 27.0 3.8 10.7 12.5 15.2 1.2 0.0 20.6 10.2 1.8 4.7 7.8 1.1 16.1 8.1 25.4 120.6 10.1 84.2 15.2 65.9 27.5 0.0 0.4 0.2 291.5 75.0 10.8 68.7 41.0 72.4 20.8 17.2 12.7 1.3 14.5 14.4 19.4 0.2 14.1 12.1 42.7 13.0 16.2 57.3 2.3 38.0 20.5 20.3 20.9 26.4 20.5 22.1 23.3 21.5 23.6 20.7 23.5 19.6 53.7 6.4 8.6 2.6 3.2 0.0 85.5 0.0 80.8 0.8 12.0 16.6 9.9 7.2 2.5 7.3 0.0 8.5 22.8 4.0 13.7 6.4 0.8 1.3 11.1 25.4 4.8 8.4 1.0 31.3 5.0 53.5 2.6 1.1 90.0 1.7 13.2 1.0 45.2 0.0 2.0 36.8 0.0 34.2 0.0 0.6 14.0 79.3 0.0 16.9 30.2 62.1 11.3 5.5 0.1 18.2 1.1 36.9 3.5 15.9 3.9 8.8 0.0 1.9 138.1 72.3 77.2 0.1 0.5 20.1 0.0 8.1 28.8 3.0 7.4 40.1 SMIM5 C17orf109 ENSG00000204323 "Small integral membrane protein 5" Q71RC9 17 75633434-75641404 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 28.4" "Cell type enhanced" "Detected in many" "Collecting duct cells: 125.0;Distal tubular cells: 92.0;Endometrial ciliated cells: 69.4;Erythroid cells: 142.5;Glandular and luminal cells: 67.6;Urothelial cells: 90.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 56 "plasmacytoid DC: 207.6" "Lineage enriched" "Detected in many" 56 "dendritic cells: 207.6" "Cell line enhanced" "Detected in some" "HEL: 2.3;MCF7: 10.5;OE19: 2.8;SK-BR-3: 4.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA065332, HPA071268" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles "Golgi apparatus" "HPA065332: AB_2685471, HPA071268: AB_2686377" "unprognostic (6.97e-2)" "prognostic favorable (5.52e-4)" "unprognostic (2.13e-2)" "unprognostic (1.24e-1)" "unprognostic (9.31e-2)" "unprognostic (1.05e-4)" "unprognostic (3.29e-2)" "unprognostic (2.16e-2)" "unprognostic (1.82e-1)" "unprognostic (2.66e-2)" "unprognostic (3.52e-3)" "unprognostic (1.10e-1)" "prognostic favorable (1.12e-4)" "unprognostic (2.64e-1)" "unprognostic (4.94e-2)" "unprognostic (8.26e-2)" "unprognostic (2.58e-1)" 1.3 0.6 4.5 1.9 8.5 11.4 1.5 8.5 6.4 8.4 10.7 10.5 9.6 1.2 0.8 27.4 7.4 4.4 12.2 5.0 5.6 28.4 1.4 3.1 1.1 11.2 8.8 2.7 2.5 3.4 2.4 1.9 9.6 4.2 2.6 0.7 7.8 1.9 0.5 14.3 15.2 0.5 7.2 4.8 10.1 2.2 7.8 0.6 15.9 0.3 3.6 6.1 14.6 16.4 1.8 1.2 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 1.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 2.3 0.4 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 10.5 0.1 0.0 0.0 2.8 0.1 0.3 0.3 0.0 0.0 2.0 0.8 0.0 0.0 4.5 0.0 0.3 0.6 0.1 0.1 0.2 0.1 0.1 0.1 0.2 0.0 0.1 0.0 0.5 0.5 1.1 0.3 0.6 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 3.7 0.1 0.0 207.6 0.0 13.7 4.5 8.5 8.5 6.4 5.0 5.6 11.2 8.8 9.6 7.2 7.8 16.4 0.7 9.6 7.0 0.7 1.6 1.1 7.3 4.8 0.6 1.5 1.2 0.9 25.1 10.0 13.9 125.0 2.1 3.1 51.9 48.4 92.0 2.9 0.1 69.4 10.1 1.8 14.4 142.5 0.0 0.5 5.8 2.3 26.0 67.6 0.0 0.3 1.8 0.2 0.7 0.0 0.0 16.1 44.7 0.6 0.9 0.3 0.6 17.0 7.2 0.0 1.2 3.3 1.0 0.0 17.9 10.7 54.2 1.5 0.9 7.4 15.5 0.9 48.0 2.1 0.0 1.4 3.1 0.4 0.5 10.0 8.4 32.8 0.8 0.3 2.3 90.6 SMIM8 "C6orf162, dJ102H19.2, DKFZP586E1923" ENSG00000111850 "Small integral membrane protein 8" Q96KF7 6 87322583-87399749 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007401, HPA067453" Approved Approved Vesicles NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Vesicles "HPA007401: AB_1078357, HPA067453: AB_2685844" "unprognostic (2.54e-1)" "unprognostic (5.24e-2)" "unprognostic (1.19e-1)" "unprognostic (1.90e-1)" "unprognostic (1.56e-2)" "unprognostic (3.16e-2)" "unprognostic (3.09e-2)" "unprognostic (6.17e-2)" "unprognostic (5.31e-2)" "unprognostic (6.12e-3)" "unprognostic (1.86e-5)" "unprognostic (1.98e-1)" "unprognostic (1.34e-1)" "unprognostic (2.01e-1)" "unprognostic (3.06e-2)" "unprognostic (2.86e-2)" "unprognostic (4.01e-1)" 5.0 5.0 8.0 3.8 8.0 6.0 5.2 8.5 9.5 6.4 8.1 6.0 5.2 6.5 6.7 4.1 5.5 2.7 7.7 8.1 8.3 7.3 7.0 3.9 5.0 7.8 8.0 6.5 4.7 6.2 7.2 3.4 7.8 4.7 4.6 8.7 4.0 3.9 10.6 4.3 4.8 4.1 8.1 4.1 4.1 4.9 8.5 6.7 4.8 8.7 4.0 5.3 5.5 8.0 5.3 4.6 9.3 16.2 5.3 6.0 4.1 5.8 4.5 4.8 9.2 3.2 4.8 10.8 6.8 5.8 8.4 6.5 7.6 4.4 9.1 9.6 8.2 15.9 5.2 6.4 5.0 16.8 5.5 5.7 5.9 4.9 5.2 5.4 7.0 13.8 18.1 17.7 5.5 4.0 10.1 13.3 5.7 7.9 7.1 16.1 13.8 6.2 6.2 5.2 15.9 6.5 8.5 5.0 10.1 8.4 4.6 16.5 6.8 2.5 7.2 10.8 5.7 7.8 13.6 7.2 8.1 7.9 7.6 5.8 8.8 15.7 11.2 8.6 11.4 18.5 13.2 13.6 10.1 11.4 19.3 16.9 14.7 9.7 10.3 8.5 18.4 9.1 8.0 8.0 8.5 9.5 8.1 8.3 7.8 8.0 7.8 8.1 8.5 8.0 19.4 12.8 5.8 18.9 17.6 13.8 20.6 29.7 8.6 24.4 12.8 16.0 47.3 17.2 16.6 23.9 37.5 17.7 8.7 8.0 45.0 10.7 18.7 32.1 19.0 15.0 8.5 17.1 21.7 10.3 12.3 17.8 12.8 9.6 5.1 31.4 22.5 13.8 14.9 37.0 19.8 9.4 36.7 12.3 11.5 14.5 15.8 11.1 8.8 8.4 11.0 28.4 13.4 8.0 13.3 8.1 11.6 20.7 14.0 10.1 15.5 23.0 17.5 22.9 26.3 21.1 17.9 23.9 28.4 10.7 14.8 14.9 14.8 30.7 16.5 13.4 SMOX "C20orf16, dJ779E11.1, FLJ20746, MGC1010, PAO, PAOh1, SMO" ENSG00000088826 "Spermine oxidase" Q9NWM0 20 4120980-4187747 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 61.3" "Cell type enhanced" "Detected in many" "Ductal cells: 48.4;Erythroid cells: 89.7;Macrophages: 73.3;Pancreatic endocrine cells: 131.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 1.0;myeloid DC: 2.4;neutrophil: 3.6;plasmacytoid DC: 1.1" "Group enriched" "Detected in many" 6 "dendritic cells: 2.4;granulocytes: 3.6;monocytes: 1.0" "Cell line enhanced" "Detected in many" "A549: 119.6;Karpas-707: 201.7;RPTEC TERT1: 91.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047117, HPA060198" Approved Supported "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" Nucleoplasm "Nuclear membrane, Vesicles, Cytosol" "HPA047117: AB_2679940, HPA060198: AB_2684220" "unprognostic (1.24e-2)" "unprognostic (6.55e-2)" "unprognostic (7.24e-3)" "unprognostic (2.77e-1)" "unprognostic (1.40e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (3.33e-6)" "prognostic unfavorable (1.36e-4)" "unprognostic (4.92e-2)" "unprognostic (3.37e-1)" "unprognostic (7.18e-2)" "unprognostic (7.58e-2)" "prognostic unfavorable (1.06e-4)" "unprognostic (4.08e-2)" "unprognostic (2.64e-3)" "unprognostic (1.26e-2)" "unprognostic (3.07e-1)" 8.5 4.4 50.9 4.4 61.3 32.2 5.3 54.5 60.9 17.7 32.8 5.6 10.6 10.8 7.1 8.5 7.4 15.1 6.8 46.3 51.7 20.5 8.5 4.9 4.8 56.6 54.4 12.5 32.5 25.2 13.2 6.2 53.7 12.2 1.2 2.9 12.1 7.9 4.3 11.9 8.1 4.0 53.0 6.4 20.1 5.8 55.5 4.3 6.8 2.8 2.6 8.2 12.4 54.1 11.0 119.6 8.3 6.3 5.5 8.2 14.6 15.6 29.8 11.1 7.4 49.5 29.6 0.0 5.1 14.4 18.0 21.6 6.8 7.5 4.8 0.0 3.5 21.5 4.1 50.6 35.0 4.1 8.3 31.3 13.1 23.1 9.8 13.4 19.8 16.7 4.8 201.7 6.7 3.3 8.1 12.1 10.2 10.7 16.3 7.3 10.3 29.1 91.4 8.3 1.6 7.2 28.9 3.4 54.1 4.2 0.3 5.1 24.0 12.7 12.0 2.3 12.2 9.1 1.7 0.1 10.6 5.4 9.8 0.0 1.0 0.2 0.0 0.4 0.0 0.1 0.2 0.2 2.4 0.0 0.0 0.0 3.6 0.3 0.1 1.1 0.0 16.0 50.9 61.3 54.5 60.9 46.3 51.7 56.6 54.4 53.7 53.0 55.5 54.1 4.4 0.0 0.5 38.5 3.8 12.6 12.0 14.4 6.8 0.5 6.9 4.6 1.7 12.8 6.3 11.0 0.0 0.4 0.2 1.4 0.0 48.4 4.0 9.2 15.8 11.2 6.0 89.7 1.6 30.5 0.8 11.3 6.6 18.7 5.7 10.4 13.6 2.3 20.6 0.0 3.5 3.0 6.1 3.1 10.2 7.7 14.6 73.3 8.8 5.6 22.6 25.4 1.0 9.0 6.2 131.3 1.5 13.5 7.4 13.1 4.0 3.8 1.2 1.4 0.0 2.7 10.2 19.1 7.8 2.1 10.5 0.3 2.1 1.9 3.7 12.6 SMPD2 "ISC1, nSMase" ENSG00000135587 "Sphingomyelin phosphodiesterase 2" O60906 6 109440724-109443919 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 53.0" "Cell type enhanced" "Detected in many" "Early spermatids: 179.4;Late spermatids: 359.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018110, HPA018125" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 71: Testis - DNA repair" "Cluster 28: BEWO - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "Cell Junctions" "HPA018110: AB_1857292, HPA018125: AB_1857293" "unprognostic (1.61e-1)" "unprognostic (8.01e-2)" "unprognostic (1.97e-1)" "unprognostic (8.79e-3)" "unprognostic (3.88e-2)" "unprognostic (2.38e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (7.08e-2)" "unprognostic (7.59e-2)" "unprognostic (1.41e-1)" "prognostic favorable (1.00e-3)" "unprognostic (3.60e-2)" "unprognostic (2.14e-3)" "unprognostic (7.94e-2)" "unprognostic (2.25e-1)" "unprognostic (1.45e-2)" "prognostic favorable (1.70e-4)" 6.9 8.8 7.6 8.6 7.4 12.7 10.5 9.6 7.8 12.6 15.1 12.7 13.5 7.1 15.5 24.5 21.4 8.7 6.7 7.7 6.9 12.2 7.6 9.7 13.3 7.6 7.9 8.2 17.7 22.1 11.1 6.0 7.2 13.2 12.6 6.5 15.6 5.8 4.1 21.7 12.3 4.9 7.6 13.3 14.2 53.0 7.0 10.3 13.3 1.7 17.1 10.4 14.3 8.8 13.1 14.8 7.7 12.2 13.2 7.1 25.5 4.3 15.7 10.5 9.8 14.0 10.3 7.1 9.0 9.3 22.1 16.4 7.8 18.7 6.3 9.1 20.5 8.2 15.9 8.7 11.0 9.1 9.4 7.7 21.3 9.3 18.4 11.8 9.8 12.4 16.3 12.2 5.3 18.7 14.8 19.7 2.1 17.3 7.5 10.4 3.6 7.7 19.3 21.8 10.1 8.4 8.2 24.9 19.3 6.2 7.9 17.2 6.3 4.7 6.8 3.8 16.3 8.3 2.3 4.6 9.1 8.6 8.5 6.2 9.0 10.8 6.9 8.6 7.8 14.4 7.8 8.2 11.2 20.4 5.6 5.9 2.5 7.3 7.8 14.3 8.2 6.0 7.6 7.4 9.6 7.8 7.7 6.9 7.6 7.9 7.2 7.6 7.0 8.8 3.9 12.8 7.2 1.6 15.9 9.8 12.9 13.8 8.6 1.3 8.9 6.7 2.1 7.2 11.8 12.9 4.2 10.3 9.1 26.1 1.9 19.2 179.4 28.4 4.0 4.4 8.4 4.2 1.4 19.8 18.5 6.1 25.0 4.3 0.0 3.5 3.6 3.6 9.5 0.0 0.5 27.1 14.2 4.1 11.2 359.7 9.3 7.2 8.8 2.8 9.9 3.7 6.2 0.0 1.7 15.4 27.7 9.1 9.8 15.0 37.5 9.3 67.1 4.9 13.1 3.1 5.8 69.9 10.9 13.8 18.6 17.0 7.6 8.7 17.8 16.9 SMU1 "BWD, FLJ10805, fSAP57, SMU-1" ENSG00000122692 "SMU1 DNA replication regulator and spliceosomal factor" Q2TAY7 9 33041765-33076674 "Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019708 Supported Approved Vesicles NA NA 25000 "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA019708: AB_1857300" "unprognostic (2.20e-2)" "prognostic favorable (2.66e-4)" "unprognostic (1.17e-1)" "unprognostic (1.58e-1)" "unprognostic (1.80e-2)" "unprognostic (8.44e-2)" "unprognostic (2.59e-3)" "unprognostic (5.06e-2)" "unprognostic (3.04e-2)" "prognostic favorable (1.25e-4)" "unprognostic (4.98e-3)" "unprognostic (3.15e-1)" "prognostic favorable (1.67e-5)" "unprognostic (1.09e-2)" "unprognostic (7.04e-2)" "unprognostic (8.71e-2)" "unprognostic (5.96e-2)" 11.5 11.3 11.2 10.6 13.0 16.0 11.9 13.9 12.1 11.4 8.6 10.9 8.6 13.1 11.8 10.6 11.4 8.6 10.3 10.7 11.5 11.2 12.9 10.0 12.8 12.4 11.9 14.7 8.2 15.8 8.1 8.4 12.4 11.9 10.9 12.6 9.3 11.5 14.4 12.8 9.4 13.2 12.6 12.1 9.1 8.5 11.7 14.1 11.2 13.0 15.2 11.5 9.9 16.6 26.3 20.4 24.0 20.9 25.4 19.3 18.7 20.1 18.1 26.9 26.5 20.8 10.7 33.0 14.4 25.1 14.6 15.7 31.1 24.1 29.7 38.1 14.9 24.8 33.4 24.5 22.1 43.5 22.4 20.4 27.0 24.9 17.6 20.1 22.9 22.7 23.4 20.5 22.7 12.1 34.2 46.3 33.1 19.6 21.4 28.8 19.9 17.9 20.5 19.4 20.3 17.7 27.2 19.4 13.1 18.6 18.7 15.7 24.6 17.2 19.1 25.2 23.8 9.1 18.1 38.0 19.2 20.2 12.5 23.4 13.9 11.5 12.4 15.4 13.3 12.9 14.0 11.6 15.8 11.7 13.9 14.3 8.1 12.4 17.9 20.0 12.6 10.8 11.2 13.0 13.9 12.1 10.7 11.5 12.4 11.9 12.4 12.6 11.7 16.6 45.5 25.6 31.4 17.9 48.0 53.7 45.7 41.0 43.3 29.5 23.8 22.4 30.6 30.0 39.9 20.2 37.5 34.9 72.7 19.1 21.5 32.3 29.6 41.6 42.8 38.2 28.1 24.4 23.4 24.3 36.3 37.7 17.9 47.3 39.2 32.1 21.4 29.4 30.8 23.5 25.3 19.5 44.7 29.2 40.8 8.7 32.3 40.2 23.2 14.0 39.7 34.8 32.0 21.6 28.3 27.9 20.1 25.9 28.3 33.3 18.1 31.7 44.1 39.3 19.7 53.9 44.7 41.4 30.5 36.3 57.5 57.7 43.7 37.0 23.5 35.5 SMURF1 KIAA1625 ENSG00000198742 "SMAD specific E3 ubiquitin protein ligase 1" Q9HCE7 7 99027440-99144108 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 100.2;Microglial cells: 89.9;Oligodendrocytes: 211.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 9.2;BJ: 15.2;EFO-21: 12.8;HDLM-2: 8.1;PC-3: 18.2;U-2 OS: 8.3;U-251 MG: 9.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019671, HPA055245" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Nucleoplasm "HPA019671: , HPA055245: AB_2682757" "unprognostic (2.21e-1)" "unprognostic (6.15e-2)" "unprognostic (8.88e-2)" "unprognostic (1.04e-1)" "unprognostic (1.96e-2)" "unprognostic (1.42e-1)" "unprognostic (1.29e-1)" "unprognostic (1.73e-1)" "unprognostic (2.00e-1)" "unprognostic (2.15e-2)" "unprognostic (3.92e-3)" "unprognostic (2.58e-1)" "unprognostic (1.46e-1)" "unprognostic (7.83e-2)" "unprognostic (1.68e-1)" "unprognostic (3.81e-1)" "unprognostic (4.62e-2)" 17.7 13.9 0.7 0.3 0.8 1.1 14.3 0.5 0.9 13.4 1.1 12.7 0.0 12.3 0.0 22.0 12.2 0.0 9.0 0.8 0.3 11.6 11.7 18.5 0.0 1.1 0.7 20.6 15.5 0.0 11.2 0.0 1.0 13.3 0.0 0.7 15.0 0.0 12.7 20.2 11.7 0.0 0.1 10.0 16.1 20.9 0.8 0.0 8.5 0.0 0.0 12.4 15.5 1.8 9.2 0.0 0.1 0.2 0.0 0.0 1.3 15.2 0.1 0.4 0.0 0.0 0.4 1.6 12.8 0.0 0.3 4.5 0.0 0.1 0.0 8.1 2.3 0.0 0.7 0.7 0.1 0.1 3.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 5.9 0.1 0.8 0.1 1.3 1.9 2.8 0.0 18.2 2.5 1.2 0.0 0.0 0.4 0.3 1.5 0.7 0.5 0.9 0.3 0.3 0.0 1.4 0.0 8.3 1.3 9.4 2.0 4.9 1.3 0.6 1.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.8 0.5 0.9 0.8 0.3 1.1 0.7 1.0 0.1 0.8 1.8 9.7 19.2 27.5 59.4 8.9 25.9 25.5 10.0 25.0 28.2 10.3 7.2 4.4 20.0 18.5 12.9 8.4 7.7 4.6 17.1 1.9 14.7 6.2 13.3 8.8 12.8 11.4 0.4 100.2 16.0 10.3 10.8 46.9 23.3 2.5 6.8 9.7 9.3 6.6 26.9 77.0 11.0 4.1 4.1 10.9 8.5 6.2 8.8 8.8 89.9 5.5 3.3 5.2 70.4 211.9 34.8 14.9 13.9 5.4 37.9 7.1 5.5 22.1 7.6 6.6 10.4 15.1 32.8 2.4 19.3 22.0 21.1 8.8 6.5 8.1 77.5 SMYD4 "KIAA1936, ZMYND21" ENSG00000186532 "SET and MYND domain containing 4" Q8IYR2 17 1779485-1830634 "Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030059 Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "Nucleoplasm, Cytosol" "HPA030059: AB_2191728" "unprognostic (1.45e-1)" "unprognostic (2.48e-1)" "unprognostic (2.47e-1)" "unprognostic (4.23e-2)" "unprognostic (1.13e-2)" "unprognostic (3.66e-2)" "unprognostic (4.03e-2)" "unprognostic (1.04e-1)" "unprognostic (1.79e-2)" "unprognostic (4.95e-2)" "unprognostic (1.83e-3)" "unprognostic (9.26e-3)" "unprognostic (3.63e-2)" "unprognostic (1.33e-2)" "unprognostic (7.35e-2)" "unprognostic (1.52e-1)" "unprognostic (1.18e-1)" 7.4 6.6 4.1 6.0 3.6 3.4 7.3 8.0 4.5 7.9 3.7 7.5 7.0 6.5 5.0 3.9 7.3 3.6 7.0 3.5 3.5 3.7 4.9 5.6 6.8 3.7 3.2 9.5 6.7 3.6 6.6 4.7 4.0 6.5 4.8 7.6 7.3 5.6 13.7 6.6 7.4 5.9 2.2 6.3 4.9 5.8 4.3 6.2 5.7 10.2 6.5 7.2 6.2 5.6 7.4 13.7 13.5 9.6 9.0 6.1 15.7 11.9 6.7 12.3 12.5 22.0 6.2 19.7 7.8 4.8 8.3 14.2 12.9 7.7 15.3 5.7 13.1 7.2 15.9 6.0 4.5 7.4 6.8 4.4 6.8 12.7 11.1 6.3 6.2 16.6 7.6 7.5 9.7 4.6 13.6 5.3 6.2 8.7 6.6 16.7 6.9 5.0 4.9 8.8 5.5 7.6 11.0 4.5 11.1 10.9 6.7 4.5 5.9 12.0 6.1 10.0 10.4 5.2 7.5 7.1 6.8 6.4 11.9 12.0 2.4 2.3 5.1 3.0 4.3 4.0 3.0 3.3 1.5 2.7 3.4 5.0 1.3 3.1 2.4 4.5 3.5 2.1 4.1 3.6 8.0 4.5 3.5 3.5 3.7 3.2 4.0 2.2 4.3 5.6 22.9 6.4 27.8 6.5 12.9 5.0 9.3 11.9 14.8 19.3 6.9 8.4 6.3 14.3 14.0 7.3 33.3 9.7 16.5 6.9 1.9 5.7 20.2 3.7 8.9 10.9 3.6 9.7 11.7 3.3 10.9 14.2 4.1 3.5 7.6 14.7 17.2 6.7 12.9 26.9 12.1 5.2 12.2 23.3 9.2 5.9 27.1 17.4 5.4 13.1 16.4 7.9 43.3 4.5 7.1 4.2 2.0 24.8 10.1 7.2 23.3 2.9 17.8 19.9 46.0 43.6 23.9 12.6 14.8 5.1 6.7 8.1 12.1 6.1 6.4 3.5 SNAP25 "bA416N4.2, dJ1068F16.2, RIC-4, RIC4, SEC9, SNAP, SNAP-25" ENSG00000132639 "Synaptosome associated protein 25" P60880 20 10218830-10307418 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transporters" "Congenital myasthenic syndrome, Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 20 "brain: 1658.7;retina: 492.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 559.2;Excitatory neurons: 1015.8;Inhibitory neurons: 552.8;Rod photoreceptor cells: 254.4" "Cancer enriched" "Detected in many" 4 "glioma: 28.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 23.8;SCLC-21H: 78.2;SH-SY5Y: 46.6;U-87 MG: 56.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000360, HPA001830, HPA071013" Enhanced Supported Approved "Vesicles,Plasma membrane" NA NA 9000 "Cluster 6: Brain - Smell perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Vesicles "CAB000360: AB_2286342, HPA001830: AB_1080039, HPA071013: " "unprognostic (1.64e-3)" "unprognostic (7.26e-3)" "unprognostic (4.36e-2)" "unprognostic (2.49e-7)" "unprognostic (6.86e-3)" "unprognostic (5.87e-3)" "unprognostic (1.15e-2)" "unprognostic (9.94e-2)" "unprognostic (3.13e-1)" "unprognostic (5.82e-3)" "unprognostic (4.80e-3)" "unprognostic (8.06e-2)" "unprognostic (1.09e-1)" "unprognostic (6.18e-3)" "unprognostic (2.48e-1)" "unprognostic (6.28e-3)" "unprognostic (1.02e-2)" 1.5 43.6 251.0 4.1 383.5 0.2 4.4 598.0 1658.7 0.8 0.0 5.7 3.7 7.9 12.9 0.5 7.7 2.3 3.2 420.4 142.2 1.4 1.0 1.8 0.4 427.4 24.7 6.9 6.3 1.2 54.3 0.6 386.6 3.2 2.3 492.0 0.5 19.6 0.8 0.7 3.9 8.1 38.1 0.2 6.3 3.6 147.6 0.5 0.7 0.1 0.4 1.1 1.6 726.9 0.0 4.7 3.9 0.0 0.4 0.1 0.0 2.0 0.0 4.8 1.4 0.0 0.0 0.0 4.3 0.0 3.4 0.8 0.6 0.0 9.6 0.5 0.3 0.0 6.8 0.7 3.5 0.0 0.5 4.4 0.0 3.9 0.0 10.7 0.0 2.8 0.0 23.8 1.6 0.0 0.0 0.0 0.8 3.0 0.0 0.0 0.0 0.1 0.9 0.0 78.2 46.6 0.7 0.1 0.0 2.4 0.0 6.5 0.0 5.0 6.8 0.0 2.3 0.1 12.9 0.1 56.0 0.0 4.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 251.0 383.5 598.0 1658.7 420.4 142.2 427.4 24.7 386.6 38.1 147.6 726.9 0.5 0.0 0.0 117.2 0.0 0.8 1.4 0.1 0.0 559.2 0.2 1.3 0.5 8.6 0.0 0.0 106.3 0.0 0.2 0.0 0.0 0.2 16.3 0.1 0.7 5.2 43.5 0.0 1015.8 0.0 0.1 3.9 0.0 0.2 0.0 0.6 0.0 0.2 0.1 65.6 552.8 3.4 0.0 0.0 0.4 83.3 17.1 0.1 1.8 120.9 0.0 71.9 0.0 179.4 113.3 1.0 2.6 68.8 0.0 0.6 0.1 3.0 0.0 254.4 0.0 0.0 1.3 1.1 0.4 0.0 0.9 0.0 0.0 2.6 0.1 0.1 SNRK "FLJ20224, HSNFRK, KIAA0096" ENSG00000163788 "SNF related kinase" Q9NRH2 3 43286512-43424764 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 124.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 126.0;TIME: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042163 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Vesicles, Plasma membrane, Cell Junctions" Nucleoplasm "HPA042163: AB_10794645" "prognostic favorable (9.28e-4)" "unprognostic (8.46e-2)" "unprognostic (2.79e-3)" "unprognostic (6.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.16e-3)" "unprognostic (2.00e-2)" "unprognostic (1.08e-1)" "unprognostic (2.63e-3)" "unprognostic (4.25e-1)" "unprognostic (2.32e-1)" "unprognostic (4.68e-2)" "prognostic favorable (9.41e-5)" "unprognostic (9.21e-3)" "unprognostic (2.04e-1)" "unprognostic (7.06e-3)" "unprognostic (7.38e-2)" 37.6 10.3 9.7 17.2 9.7 58.4 26.5 27.7 13.2 21.7 9.8 14.6 16.1 23.1 7.8 19.7 13.6 20.4 16.3 9.5 12.5 20.0 25.4 26.4 19.8 14.0 11.5 14.4 22.7 18.5 11.4 33.3 14.7 11.2 11.9 18.8 11.4 10.8 14.3 30.3 17.2 22.9 9.5 33.0 14.4 11.1 13.2 40.5 27.3 21.6 14.7 19.8 21.7 8.7 8.4 5.0 9.1 8.8 26.6 9.5 8.7 8.8 14.8 9.4 9.1 6.9 11.8 13.2 6.8 11.2 6.2 5.3 10.7 18.9 9.6 15.1 8.8 15.0 9.1 8.1 13.8 17.1 16.1 10.5 12.7 10.6 17.9 9.5 126.0 14.9 6.7 14.9 8.7 4.4 17.3 15.0 10.1 4.6 22.6 11.7 6.7 14.0 24.2 14.1 6.4 13.4 7.7 8.1 11.1 7.9 5.5 21.4 74.1 8.2 8.3 9.5 10.4 23.7 18.3 11.0 5.8 20.1 12.0 9.4 4.2 7.6 9.5 7.5 13.0 3.6 8.3 9.6 4.0 3.6 12.1 13.1 27.7 11.0 7.1 1.2 9.7 9.7 9.7 9.7 27.7 13.2 9.5 12.5 14.0 11.5 14.7 9.5 13.2 8.7 88.4 32.1 24.1 30.0 29.0 52.8 10.3 6.4 12.5 52.1 9.7 8.6 17.7 15.7 15.0 16.5 16.7 7.7 57.6 37.0 11.7 10.9 50.4 23.3 16.2 84.2 10.8 10.3 21.6 8.9 3.2 16.4 12.8 19.8 14.5 8.9 98.6 25.2 13.7 30.3 43.2 10.7 12.2 24.8 19.0 7.5 12.5 26.5 23.2 34.7 21.9 16.3 65.9 24.6 10.7 11.2 20.6 11.7 27.3 12.7 25.2 12.2 19.2 18.3 124.9 31.3 49.1 11.1 16.2 13.7 51.3 8.2 61.2 9.5 11.1 18.0 SNX11 ENSG00000002919 "Sorting nexin 11" Q9Y5W9 17 48103357-48123601 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 37.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044787, HPA054660" Approved Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Endoplasmic reticulum" Vesicles "HPA044787: AB_10795988, HPA054660: AB_2682560" "unprognostic (1.75e-1)" "unprognostic (6.86e-3)" "unprognostic (4.34e-2)" "unprognostic (4.33e-3)" "unprognostic (2.45e-1)" "unprognostic (1.54e-1)" "unprognostic (2.68e-3)" "unprognostic (2.07e-1)" "unprognostic (9.27e-2)" "unprognostic (2.15e-1)" "unprognostic (5.42e-2)" "unprognostic (2.12e-1)" "unprognostic (5.22e-3)" "unprognostic (9.02e-3)" "unprognostic (2.70e-2)" "unprognostic (9.50e-2)" "unprognostic (3.89e-2)" 14.3 12.0 18.0 18.1 19.1 21.5 11.1 18.2 19.4 10.5 16.4 13.8 8.7 10.5 12.5 19.9 9.6 8.9 12.5 18.3 18.4 15.8 14.5 11.4 21.7 20.1 18.9 8.8 11.7 13.4 10.7 11.3 18.8 12.1 12.5 11.9 12.2 8.7 12.8 11.6 12.4 17.0 20.1 24.0 12.4 11.4 19.8 16.1 20.0 15.3 29.1 13.3 11.6 20.7 20.6 25.4 21.9 21.1 18.1 8.3 22.8 21.8 13.9 26.5 28.8 36.0 17.7 21.6 27.3 24.1 15.5 18.6 21.2 21.0 29.2 52.4 24.5 32.5 17.5 17.5 18.4 36.0 22.7 13.8 20.8 25.1 23.7 16.5 22.4 20.4 19.8 21.7 17.4 17.0 21.8 22.8 12.2 23.6 21.3 13.5 39.7 24.8 16.1 20.1 15.7 28.6 14.2 9.7 37.7 26.6 20.1 25.4 18.8 30.6 18.2 20.3 26.3 34.0 54.1 26.0 22.1 16.4 19.6 28.7 34.6 35.6 19.0 43.3 13.1 22.1 10.5 12.9 28.2 21.2 8.6 14.7 92.9 16.8 54.5 12.9 10.1 24.0 18.0 19.1 18.2 19.4 18.3 18.4 20.1 18.9 18.8 20.1 19.8 20.7 8.7 6.4 2.0 2.9 15.4 6.0 5.0 5.9 7.4 8.9 6.4 6.2 5.3 1.5 4.3 16.5 2.1 11.7 14.2 13.3 5.9 11.4 1.9 6.2 4.6 8.0 14.9 3.6 4.1 15.3 12.2 6.0 6.6 7.1 2.5 5.4 6.1 6.9 19.9 15.2 3.9 9.0 6.1 23.2 4.6 2.1 5.3 15.9 5.4 2.8 37.5 14.2 14.4 5.0 8.8 18.1 5.6 6.8 6.3 6.9 9.9 9.9 2.9 9.3 13.1 4.6 8.8 10.3 21.2 8.9 5.1 16.4 7.5 7.7 8.0 6.4 SNX14 RGS-PX2 ENSG00000135317 "Sorting nexin 14" Q9Y5W7 6 85505496-85594156 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Disease variant, Mental retardation, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 173.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017639 Approved Supported Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Vesicles, Cytosol" "HPA017639: AB_1857345" "unprognostic (1.16e-2)" "unprognostic (3.29e-2)" "unprognostic (2.19e-2)" "unprognostic (1.52e-2)" "unprognostic (5.23e-2)" "prognostic unfavorable (2.78e-4)" "unprognostic (1.92e-2)" "unprognostic (3.45e-2)" "unprognostic (4.60e-1)" "unprognostic (1.57e-2)" "unprognostic (3.14e-2)" "unprognostic (2.37e-2)" "unprognostic (1.10e-3)" "unprognostic (1.02e-1)" "unprognostic (1.38e-1)" "unprognostic (1.87e-3)" "unprognostic (4.72e-3)" 27.3 39.9 39.0 23.0 40.5 31.4 41.7 44.4 61.0 30.8 49.7 39.7 29.8 23.5 57.3 24.3 28.2 28.3 24.8 40.7 47.0 54.4 69.6 39.6 32.6 40.1 40.7 26.8 43.6 47.1 36.3 36.2 43.1 33.2 35.1 47.2 27.8 30.8 16.4 28.6 31.7 22.4 40.9 37.4 45.3 87.0 42.5 18.9 40.5 12.9 28.8 35.1 24.7 44.2 46.1 27.3 44.5 64.9 98.3 71.6 46.0 58.0 78.5 44.2 67.5 49.0 75.4 60.3 69.8 74.4 85.9 60.7 30.5 58.8 69.4 53.3 18.0 66.1 36.4 75.1 80.9 62.4 65.0 63.0 43.7 52.0 51.6 81.1 79.4 23.2 67.7 50.4 96.9 52.1 4.4 117.0 18.3 72.1 31.1 26.2 90.6 29.1 107.1 82.7 19.8 44.5 35.0 76.6 56.3 57.9 47.9 108.9 71.6 35.4 21.8 44.1 60.3 50.4 87.0 22.8 71.3 72.2 71.8 36.7 21.5 33.0 19.9 33.6 14.7 13.3 13.4 18.1 26.2 14.7 12.0 15.0 9.9 22.9 40.9 7.9 16.7 15.7 39.0 40.5 44.4 61.0 40.7 47.0 40.1 40.7 43.1 40.9 42.5 44.2 28.5 93.0 47.2 76.4 25.3 14.7 18.7 32.8 15.9 36.4 23.3 15.1 16.9 15.7 39.1 22.0 56.3 50.4 32.6 30.7 5.9 31.7 87.1 37.3 22.2 26.9 31.8 13.2 115.2 41.6 31.9 23.1 37.8 32.5 31.6 36.0 26.0 28.7 35.4 15.2 124.4 26.1 65.1 37.7 22.3 21.6 19.6 33.4 28.4 63.7 43.1 26.1 41.2 85.5 91.0 34.4 22.0 29.3 23.8 15.7 31.9 25.1 58.9 40.7 19.7 26.2 33.0 173.0 14.9 15.9 14.8 56.5 26.4 26.5 28.6 17.7 SNX15 ENSG00000110025 "Sorting nexin 15" Q9NRS6 11 65027439-65040572 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Distal enterocytes: 5.6;Enteroendocrine cells: 7.8;granulocytes: 8.2;monocytes: 7.9;Paneth cells: 8.0;Proximal enterocytes: 6.5;Undifferentiated cells: 5.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038955 Approved Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli, Cytosol" "Vesicles, Plasma membrane" "HPA038955: AB_10672834" "unprognostic (2.00e-2)" "unprognostic (4.90e-2)" "unprognostic (3.93e-1)" "unprognostic (9.61e-4)" "unprognostic (2.79e-1)" "unprognostic (4.06e-3)" "unprognostic (4.45e-3)" "unprognostic (4.74e-2)" "unprognostic (1.09e-1)" "unprognostic (9.55e-2)" "unprognostic (8.93e-3)" "unprognostic (1.79e-2)" "unprognostic (8.84e-2)" "unprognostic (7.86e-2)" "unprognostic (2.93e-2)" "unprognostic (1.88e-1)" "unprognostic (2.68e-4)" 17.1 13.3 17.3 10.2 18.5 10.5 15.3 19.4 19.2 16.6 9.0 22.5 15.3 15.8 6.4 14.9 12.9 7.4 15.0 18.4 17.1 17.0 10.1 11.9 9.3 19.3 18.2 14.8 12.7 10.7 9.4 7.3 16.1 12.9 8.8 5.8 12.3 10.9 25.7 17.5 16.8 8.9 16.1 10.8 16.4 5.3 17.8 9.4 10.6 15.5 7.4 18.0 14.9 18.5 31.1 22.3 14.7 14.2 17.3 12.4 7.9 10.0 13.6 23.3 21.3 17.6 23.7 30.7 16.7 17.4 29.3 16.8 16.8 15.2 9.8 47.0 14.0 15.8 18.2 30.2 18.3 10.7 24.5 10.6 22.2 24.7 14.5 13.0 14.1 22.6 27.0 19.6 12.5 18.8 29.2 36.8 15.5 12.0 21.9 23.7 8.4 34.0 17.6 6.7 25.6 19.2 25.3 23.0 23.2 9.7 23.4 18.6 27.5 23.5 22.9 24.1 14.7 20.9 38.3 30.3 23.2 14.5 8.4 9.2 13.6 13.6 7.6 16.2 6.2 8.9 7.8 6.8 9.4 8.7 5.6 5.1 2.1 4.3 23.6 6.4 8.3 7.3 17.3 18.5 19.4 19.2 18.4 17.1 19.3 18.2 16.1 16.1 17.8 18.5 0.3 0.0 3.3 0.0 0.8 1.0 0.1 0.4 4.0 0.0 0.5 0.3 0.4 0.0 0.2 0.0 0.0 0.4 0.1 5.6 0.0 4.8 0.0 0.1 0.2 0.9 7.8 1.3 0.0 3.1 0.6 0.4 1.1 0.1 8.2 0.4 0.7 0.1 1.0 0.0 0.0 3.3 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 7.9 0.2 0.0 0.0 0.0 3.9 8.0 0.4 1.1 0.0 6.5 0.6 0.7 0.4 0.0 0.7 1.0 0.0 0.0 1.5 0.4 0.4 1.1 0.2 5.6 0.1 SNX16 ENSG00000104497 "Sorting nexin 16" P57768 8 81799581-81842866 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 82.8;Late spermatids: 137.3;Spermatocytes: 74.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024730, HPA024731, HPA024817" Approved Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA024730: AB_10600220, HPA024731: AB_1857346, HPA024817: AB_10602313" "unprognostic (5.50e-2)" "unprognostic (3.20e-2)" "unprognostic (1.40e-1)" "unprognostic (8.41e-3)" "unprognostic (3.21e-3)" "unprognostic (7.54e-3)" "unprognostic (1.24e-3)" "unprognostic (1.33e-1)" "unprognostic (2.12e-1)" "unprognostic (2.18e-1)" "unprognostic (3.94e-2)" "unprognostic (1.43e-1)" "unprognostic (5.73e-3)" "unprognostic (7.60e-3)" "unprognostic (2.30e-1)" "unprognostic (1.35e-1)" "unprognostic (3.65e-1)" 10.1 5.2 4.7 6.0 5.7 10.7 8.2 6.6 7.6 8.6 2.5 6.3 6.4 9.7 8.3 17.3 6.2 10.8 8.1 5.3 6.6 6.6 5.5 6.7 5.1 6.1 7.4 9.6 3.1 8.9 3.7 5.5 8.6 7.3 6.6 4.9 5.7 7.7 4.6 11.2 5.7 11.9 5.8 12.0 9.0 14.9 5.7 9.4 8.7 9.4 6.7 7.0 7.7 6.7 13.8 3.8 6.6 6.3 22.9 13.7 7.3 16.6 20.2 14.1 20.6 3.4 11.1 2.2 10.0 11.4 16.5 11.0 5.1 6.8 19.5 19.9 3.1 7.1 5.2 6.2 17.4 2.9 11.5 10.5 10.6 5.4 12.5 15.8 10.0 7.8 4.5 26.0 32.9 7.2 15.6 5.1 2.8 12.6 6.2 6.6 9.5 2.4 12.7 6.7 10.9 8.3 3.1 3.9 8.3 9.8 10.3 5.5 7.7 19.5 15.6 13.5 7.2 15.1 12.5 5.7 8.4 9.1 15.7 9.2 4.5 6.1 2.1 2.8 2.0 1.6 2.5 1.7 4.0 4.4 2.9 2.8 6.2 2.6 2.4 3.0 5.0 1.9 4.7 5.7 6.6 7.6 5.3 6.6 6.1 7.4 8.6 5.8 5.7 6.7 10.6 6.4 9.4 9.8 6.4 25.2 12.1 5.0 9.6 5.5 12.1 7.6 8.8 7.2 9.3 5.5 4.2 2.3 3.7 7.5 5.9 5.9 82.8 9.4 7.8 11.5 3.0 8.2 24.7 6.0 4.0 8.5 10.7 16.2 8.2 5.0 13.9 3.5 5.7 55.5 18.4 6.2 8.2 7.0 10.0 137.3 23.3 7.2 3.6 8.4 2.3 4.3 1.0 23.1 22.2 6.7 5.5 16.1 8.6 12.6 3.7 7.3 10.9 5.2 19.7 12.1 9.3 74.2 26.5 13.0 32.0 9.9 5.4 4.2 4.7 20.7 SNX17 KIAA0064 ENSG00000115234 "Sorting nexin 17" Q15036 2 27370496-27377535 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043867 Supported Enhanced Vesicles,Cytosol No No "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles Cytosol "HPA043867: AB_10961129" "unprognostic (2.57e-1)" "unprognostic (7.14e-3)" "unprognostic (1.26e-1)" "unprognostic (2.61e-2)" "unprognostic (1.03e-1)" "unprognostic (2.32e-1)" "unprognostic (1.06e-3)" "unprognostic (1.86e-1)" "unprognostic (4.73e-2)" "unprognostic (4.38e-2)" "unprognostic (1.04e-2)" "unprognostic (9.25e-2)" "unprognostic (1.33e-1)" "unprognostic (6.20e-2)" "unprognostic (1.37e-1)" "unprognostic (2.39e-1)" "unprognostic (6.32e-3)" 62.5 74.6 32.2 23.1 32.6 19.8 57.0 35.3 31.8 59.7 32.1 58.5 17.3 62.8 16.6 62.2 57.7 22.1 60.3 30.3 32.7 54.6 62.9 53.8 32.3 33.5 33.1 62.4 53.9 42.5 61.1 28.1 37.1 54.2 23.3 12.8 50.3 31.6 49.2 57.0 53.3 33.4 36.3 80.8 54.1 34.1 35.0 43.9 54.3 33.9 33.8 59.8 50.9 37.0 40.1 70.0 45.3 56.4 85.9 71.5 29.0 47.3 85.2 71.8 52.2 43.5 37.8 39.5 55.4 113.9 61.9 23.7 42.4 63.8 57.9 40.7 72.5 44.8 20.3 55.4 80.9 47.6 41.6 66.9 56.7 49.6 59.5 54.1 78.3 32.7 35.5 32.8 87.2 47.7 50.2 31.3 29.2 62.5 67.1 22.7 74.0 64.9 53.5 34.1 46.3 55.1 38.6 39.0 18.1 31.9 30.5 29.6 50.6 57.4 31.6 33.8 45.5 56.8 47.5 49.4 50.0 49.8 60.9 87.5 138.7 88.9 65.6 135.2 66.9 72.7 61.2 67.6 135.6 73.2 57.5 60.6 30.8 72.2 146.9 73.8 78.5 231.9 32.2 32.6 35.3 31.8 30.3 32.7 33.5 33.1 37.1 36.3 35.0 37.0 60.8 16.0 39.1 6.5 68.3 32.5 48.2 78.3 32.5 30.9 47.1 61.3 31.5 35.8 43.3 29.5 14.6 173.5 69.3 56.9 82.2 84.0 8.9 34.4 39.9 52.7 55.1 49.2 6.8 63.9 132.7 60.3 35.2 25.6 43.1 64.5 47.5 64.9 134.9 45.4 7.7 48.3 79.3 118.1 42.7 9.7 58.4 83.4 69.4 2.8 141.9 80.1 76.2 11.1 11.2 64.8 54.1 85.0 60.3 41.4 75.4 95.3 38.6 23.2 32.9 41.4 68.4 58.0 53.2 55.0 34.4 99.6 63.2 102.1 60.0 34.9 SNX21 "C20orf161, dJ337O18.4, SNX-L" ENSG00000124104 "Sorting nexin family member 21" Q969T3 20 45833799-45843276 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Theca cells: 62.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 2.8;classical monocyte: 1.6;eosinophil: 4.8;intermediate monocyte: 2.6;non-classical monocyte: 2.0" "Group enriched" "Detected in many" 8 "granulocytes: 4.8;monocytes: 2.6" "Cell line enhanced" "Detected in many" "EFO-21: 17.9;PC-3: 29.8;U-87 MG: 18.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046359 Approved Approved "Vesicles,Centriolar satellite" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Centriolar satellite" "HPA046359: AB_10963216" "unprognostic (1.97e-1)" "unprognostic (1.84e-1)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (4.16e-2)" "unprognostic (1.17e-1)" "unprognostic (1.22e-1)" "unprognostic (1.24e-2)" "unprognostic (2.33e-1)" "unprognostic (5.71e-2)" "unprognostic (4.96e-2)" "unprognostic (1.44e-1)" "unprognostic (1.48e-1)" "unprognostic (2.26e-1)" "unprognostic (1.46e-1)" "unprognostic (1.33e-2)" "unprognostic (2.18e-1)" 25.0 27.8 4.9 1.1 4.1 0.7 18.7 5.8 7.9 26.4 4.9 15.8 3.7 28.6 0.8 14.1 24.6 5.0 14.9 3.5 2.8 11.9 6.2 10.9 1.3 9.2 5.1 30.5 4.2 3.3 10.9 2.9 6.5 14.4 1.2 0.7 9.7 4.8 31.9 47.9 7.5 1.9 3.0 7.3 11.3 6.1 7.2 0.5 9.1 6.7 0.6 25.7 19.5 4.6 4.3 6.7 1.0 6.5 7.8 7.5 4.3 6.8 5.0 5.0 4.0 5.0 3.0 0.1 17.9 4.8 4.1 5.5 0.2 4.5 0.8 0.3 1.4 0.1 4.1 4.6 3.3 0.0 1.3 3.9 2.7 4.8 0.4 1.7 3.6 1.1 0.1 0.0 0.9 11.1 0.1 0.8 1.8 0.8 29.8 0.1 0.5 0.2 1.0 0.7 1.2 11.6 14.6 10.3 8.1 0.8 5.9 1.2 6.4 6.0 7.2 17.2 5.5 0.2 0.9 0.2 18.1 0.0 4.4 2.8 1.6 4.8 0.0 2.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 2.0 0.1 0.4 0.3 4.9 4.1 5.8 7.9 3.5 2.8 9.2 5.1 6.5 3.0 7.2 4.6 11.1 9.6 8.3 25.1 1.0 10.1 4.7 6.4 8.6 18.4 8.6 8.5 4.8 7.2 10.3 5.5 8.4 4.9 0.4 10.3 25.4 10.3 3.7 5.0 27.0 10.3 9.0 0.0 4.8 11.7 5.2 37.0 6.6 7.5 0.0 27.0 10.4 4.3 4.8 15.2 5.7 9.2 4.1 7.1 10.0 18.3 19.6 5.4 10.6 3.7 3.3 14.8 1.0 8.5 6.5 8.4 5.9 17.0 0.8 3.7 15.9 15.7 6.6 15.6 6.6 16.4 20.1 0.9 2.4 4.1 22.7 2.5 2.2 62.2 7.0 3.4 SNX22 FLJ13952 ENSG00000157734 "Sorting nexin 22" Q96L94 15 64151715-64157481 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.8;thyroid gland: 38.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 28.9;B-cells: 33.4;Erythroid cells: 136.8;Oligodendrocyte precursor cells: 95.5" "Cancer enriched" "Detected in many" 7 "thyroid cancer: 47.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory B-cell: 3.3;naive B-cell: 6.1" "Lineage enriched" "Detected in many" 6 "B-cells: 6.1" "Cell line enriched" "Detected in some" 5 "Daudi: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038470 Approved Nucleoplasm,Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 6: Erythroid cells - Oxygen transport" Vesicles Nucleoplasm "HPA038470: AB_10673174" "prognostic favorable (2.89e-5)" "unprognostic (8.93e-3)" "unprognostic (2.89e-1)" "unprognostic (3.55e-2)" "unprognostic (3.24e-1)" "unprognostic (5.38e-3)" "unprognostic (2.29e-1)" "unprognostic (3.05e-2)" "unprognostic (1.94e-1)" "unprognostic (5.29e-2)" "unprognostic (2.28e-3)" "unprognostic (1.09e-1)" "unprognostic (1.27e-4)" "unprognostic (3.92e-1)" "unprognostic (2.52e-1)" "prognostic favorable (2.19e-4)" "unprognostic (1.74e-2)" 0.4 0.4 11.2 3.7 12.5 6.5 0.5 12.0 11.6 0.6 4.7 0.4 0.5 0.2 1.9 0.3 0.2 0.3 11.9 11.2 11.1 1.0 2.9 5.7 7.2 16.8 13.1 0.1 1.7 0.0 3.2 0.2 14.4 4.2 0.2 0.0 1.4 4.5 0.1 0.2 3.4 0.2 14.4 5.4 2.3 0.4 12.9 2.5 38.7 0.0 8.6 0.5 0.3 15.4 0.0 0.4 0.4 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.1 0.3 0.4 17.5 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.1 1.7 0.3 0.0 1.8 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.5 2.6 0.0 0.7 0.2 0.0 1.3 0.2 0.2 3.7 0.1 0.7 0.8 0.1 3.8 0.7 0.0 0.5 0.0 0.2 1.5 0.0 0.0 0.1 1.0 0.0 0.1 3.1 1.3 3.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 3.3 0.0 0.0 1.0 6.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 1.4 11.2 12.5 12.0 11.6 11.2 11.1 16.8 13.1 14.4 14.4 12.9 15.4 0.7 28.9 8.8 0.0 33.4 1.5 2.3 1.3 1.2 0.9 3.2 3.2 21.0 0.0 1.4 0.0 4.2 3.3 2.0 1.5 0.0 0.6 1.6 0.5 1.6 1.0 0.0 136.8 0.1 3.8 8.6 4.1 2.6 1.3 2.5 1.9 1.4 4.3 4.6 0.0 0.3 1.2 0.0 1.9 7.4 1.7 0.6 2.5 3.6 3.7 1.9 0.5 1.0 95.5 17.7 1.3 0.6 0.4 9.5 6.2 0.6 1.6 0.5 2.0 0.0 3.1 1.9 1.4 2.1 1.3 2.8 4.0 3.0 0.3 0.8 1.6 SNX24 SBBI31 ENSG00000064652 "Sorting nexin 24" Q9Y343 5 122843439-123029354 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 95.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 3.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044566, HPA073934" Approved Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA044566: AB_10797034, HPA073934: AB_2686644" "unprognostic (2.63e-1)" "unprognostic (2.50e-1)" "unprognostic (2.73e-1)" "prognostic unfavorable (7.93e-6)" "unprognostic (2.31e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (8.88e-4)" "unprognostic (1.37e-1)" "unprognostic (1.61e-1)" "unprognostic (3.42e-1)" "unprognostic (5.77e-2)" "unprognostic (3.69e-2)" "prognostic favorable (1.28e-4)" "unprognostic (2.03e-1)" "unprognostic (1.10e-1)" "unprognostic (6.94e-2)" "unprognostic (1.50e-2)" 8.1 8.1 12.3 5.5 15.1 4.5 7.5 19.0 15.5 9.5 13.1 11.1 15.2 6.5 11.8 36.8 7.6 10.5 12.3 11.4 15.6 20.6 14.1 17.3 6.5 19.3 15.6 5.9 10.6 25.6 7.8 25.3 18.6 6.1 12.5 12.5 12.3 6.5 9.5 16.8 11.5 11.0 16.9 7.7 16.4 8.7 17.1 2.5 18.5 14.0 8.8 9.2 14.2 23.9 33.2 14.7 23.5 15.8 8.5 21.7 47.2 28.7 26.7 32.9 42.1 20.8 30.0 0.0 24.0 28.3 31.9 6.7 15.2 36.8 50.3 17.8 9.3 4.7 13.4 29.8 43.4 0.2 5.4 18.3 53.4 16.6 64.4 28.5 16.0 5.7 6.1 26.3 25.1 29.5 0.8 1.3 9.6 6.0 9.3 4.2 37.3 16.3 47.8 19.8 14.4 17.2 27.1 19.7 31.2 30.4 35.5 10.4 13.9 35.4 27.3 14.0 46.6 9.1 12.9 5.0 30.3 0.6 73.4 0.0 1.4 0.0 0.6 2.8 0.3 0.3 0.6 0.5 0.7 0.2 0.2 0.1 0.0 1.3 3.2 0.1 1.4 0.5 12.3 15.1 19.0 15.5 11.4 15.6 19.3 15.6 18.6 16.9 17.1 23.9 7.8 44.8 24.6 45.4 1.1 10.5 7.5 10.6 3.4 18.3 8.7 5.8 14.9 14.3 6.3 20.2 6.2 45.1 3.7 17.7 35.2 15.6 75.8 18.6 11.1 6.5 1.2 4.0 51.8 11.8 57.1 12.6 7.1 15.0 0.0 19.1 8.6 12.9 66.1 11.8 52.1 6.7 6.1 51.9 4.7 95.9 9.0 21.0 3.6 60.9 16.0 12.4 4.1 46.8 63.5 21.9 4.4 9.4 2.7 16.2 35.2 39.9 12.0 18.0 13.1 7.0 9.1 5.0 9.6 19.5 16.8 39.7 3.9 39.2 8.9 11.8 SNX25 SBBI31 ENSG00000109762 "Sorting nexin 25" Q9H3E2 4 185204237-185370185 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 128.9;Astrocytes: 50.6;Excitatory neurons: 57.7;Inhibitory neurons: 60.7;Oligodendrocyte precursor cells: 55.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "HDLM-2: 55.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036928 Supported Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA036928: AB_10669720" "unprognostic (9.20e-2)" "unprognostic (1.31e-1)" "unprognostic (2.26e-1)" "unprognostic (4.29e-3)" "unprognostic (8.89e-2)" "unprognostic (5.63e-2)" "unprognostic (1.43e-2)" "unprognostic (6.41e-2)" "unprognostic (5.35e-2)" "unprognostic (2.99e-2)" "unprognostic (4.03e-3)" "unprognostic (1.87e-1)" "unprognostic (3.33e-1)" "unprognostic (1.13e-1)" "unprognostic (1.57e-1)" "unprognostic (1.32e-2)" "unprognostic (8.55e-3)" 7.6 8.0 7.0 7.3 8.4 2.0 9.5 17.3 7.9 6.0 23.9 12.3 3.5 6.9 6.3 7.1 9.7 8.5 8.7 7.5 8.9 11.3 9.1 29.1 11.5 9.6 10.0 7.4 10.0 13.3 10.5 11.8 9.7 14.9 6.7 25.5 6.7 8.6 10.2 6.2 7.9 7.0 8.1 9.5 6.2 12.7 8.8 2.9 16.7 8.6 12.9 7.2 5.4 7.3 11.9 6.2 7.8 11.0 20.5 15.0 11.5 35.6 17.1 17.9 14.9 5.3 8.1 33.6 3.8 26.0 12.4 4.6 8.9 7.8 20.0 55.9 14.5 5.7 7.5 12.8 11.9 3.8 8.0 10.4 8.3 15.6 8.6 36.0 15.7 6.3 12.0 33.3 23.9 3.5 1.5 6.9 6.3 1.6 5.9 4.9 9.0 8.6 43.0 4.5 16.5 11.9 7.4 2.0 30.3 10.8 4.2 4.9 30.0 10.2 6.5 9.8 15.7 29.3 12.8 7.1 16.7 2.8 12.9 0.0 0.0 0.0 0.1 0.0 0.3 0.7 0.3 0.4 0.0 1.0 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.0 7.0 8.4 17.3 7.9 7.5 8.9 9.6 10.0 9.7 8.1 8.8 7.3 9.5 25.6 128.9 50.6 12.6 4.8 4.2 2.3 4.6 15.9 7.0 3.4 6.8 0.0 7.3 5.5 31.3 4.8 5.5 5.4 0.0 4.8 5.9 11.5 8.1 9.6 0.0 0.0 57.7 2.6 4.9 4.9 5.1 10.3 1.3 3.9 12.5 8.8 2.0 6.7 60.7 4.0 2.0 3.2 2.5 4.8 9.6 2.2 21.4 32.8 0.6 5.6 3.1 55.3 21.4 3.9 1.6 9.8 11.3 9.4 5.6 2.3 6.7 15.7 0.0 4.8 5.7 9.0 16.2 2.3 6.1 5.6 7.0 10.3 3.3 5.5 SNX27 "KIAA0488, MGC20471, MY014" ENSG00000143376 "Sorting nexin 27" Q96L92 1 151612006-151699091 "Plasma proteins, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 21.4;classical monocyte: 35.8;intermediate monocyte: 30.8;myeloid DC: 16.3;neutrophil: 40.4;non-classical monocyte: 35.4" "Group enriched" "Detected in all" 5 "dendritic cells: 16.3;granulocytes: 40.4;monocytes: 35.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028551 Approved Vesicles NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA028551: " "unprognostic (3.35e-1)" "unprognostic (4.76e-1)" "unprognostic (1.38e-1)" "unprognostic (2.13e-2)" "unprognostic (2.79e-2)" "unprognostic (3.42e-1)" "unprognostic (2.41e-2)" "unprognostic (1.48e-2)" "unprognostic (1.78e-1)" "unprognostic (1.96e-1)" "unprognostic (5.92e-2)" "unprognostic (1.63e-1)" "unprognostic (5.45e-2)" "unprognostic (2.81e-1)" "unprognostic (4.15e-1)" "unprognostic (7.30e-2)" "unprognostic (1.04e-1)" 7.6 8.6 18.1 7.7 24.7 8.7 7.2 20.2 21.1 9.1 9.2 14.4 5.3 9.1 9.2 7.5 8.6 6.7 8.8 17.1 23.2 14.5 8.5 8.9 6.8 21.5 21.5 9.7 6.9 11.8 10.2 10.7 21.8 9.5 7.4 15.9 7.2 11.6 17.6 9.6 8.3 10.0 20.5 11.2 8.5 7.9 20.1 7.2 7.4 21.3 6.5 12.4 8.2 22.3 9.7 14.2 14.7 18.6 22.9 16.8 32.7 5.1 10.5 8.9 9.5 11.6 12.5 9.1 10.9 8.3 9.5 11.7 19.1 10.4 11.0 13.1 6.9 14.7 8.4 13.1 15.1 17.8 9.6 13.4 7.7 10.2 11.6 9.0 10.1 14.3 9.0 54.8 11.8 17.3 10.6 12.2 26.1 19.0 9.0 10.8 14.3 11.8 13.9 14.3 14.7 12.6 13.8 25.4 10.1 15.8 16.3 14.9 13.4 12.5 8.2 13.1 10.9 11.4 12.2 17.8 14.8 11.2 14.2 21.4 35.8 5.4 4.6 30.8 6.6 3.2 5.8 4.2 16.3 4.4 5.5 4.6 40.4 3.5 35.4 4.2 5.1 17.3 18.1 24.7 20.2 21.1 17.1 23.2 21.5 21.5 21.8 20.5 20.1 22.3 18.4 12.8 27.1 24.8 17.9 21.2 15.5 14.6 13.1 45.8 21.6 13.7 29.9 20.0 17.3 29.5 27.1 56.0 20.4 13.8 25.4 25.7 32.6 18.5 28.0 19.7 18.7 10.8 58.3 20.9 22.4 25.4 14.3 22.7 3.8 20.8 25.7 19.4 43.3 40.4 77.6 12.8 20.3 85.4 21.3 10.4 30.4 51.9 30.2 40.3 71.4 24.6 11.3 45.2 60.0 26.9 10.5 39.9 16.4 16.2 19.6 57.7 13.7 26.6 32.9 27.6 27.0 53.3 28.8 17.0 24.7 104.8 19.4 33.8 15.3 17.9 SNX5 ENSG00000089006 "Sorting nexin 5" Q9Y5X3 20 17941597-17968980 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 271.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 639.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020679, HPA051187, HPA076450" Approved Supported Vesicles,Cytosol NA NA 8200 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 18: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "CAB020679: , HPA051187: AB_2681379, HPA076450: " "unprognostic (6.00e-2)" "unprognostic (2.35e-1)" "unprognostic (3.08e-2)" "unprognostic (4.00e-2)" "unprognostic (4.47e-2)" "unprognostic (5.71e-2)" "prognostic unfavorable (2.30e-10)" "unprognostic (1.67e-1)" "unprognostic (6.19e-2)" "unprognostic (1.69e-1)" "unprognostic (2.62e-2)" "unprognostic (1.56e-1)" "unprognostic (1.77e-1)" "unprognostic (3.15e-2)" "unprognostic (6.50e-2)" "unprognostic (3.48e-2)" "unprognostic (2.99e-1)" 42.4 51.4 12.5 43.7 15.2 57.5 37.6 14.9 12.4 35.7 14.5 37.6 47.1 28.3 49.4 35.2 33.5 24.9 28.5 11.0 13.5 59.3 33.7 36.1 59.1 15.5 13.6 51.4 32.0 24.8 21.7 28.9 16.8 23.6 40.1 14.2 34.3 17.2 70.8 28.7 40.2 24.4 17.2 57.5 33.1 15.5 14.0 21.2 70.2 21.8 51.2 34.7 32.5 21.2 103.0 108.6 45.3 49.6 29.6 49.8 270.7 84.1 43.3 49.9 55.9 104.8 140.2 169.6 48.6 49.9 69.7 112.2 63.8 124.6 67.2 44.1 57.8 150.1 49.5 639.4 48.0 106.6 173.9 49.2 54.2 54.6 98.3 37.1 72.8 111.3 72.8 109.6 58.6 79.6 94.2 92.6 48.4 87.0 55.3 110.0 115.2 126.1 61.2 116.4 45.0 26.4 76.0 113.7 102.1 34.0 62.4 67.8 57.3 77.8 98.7 49.2 101.5 77.8 129.2 137.2 38.5 37.6 69.6 69.6 58.7 83.6 54.8 81.7 50.0 80.6 49.6 54.6 71.9 75.2 29.7 42.7 4.8 39.0 92.3 37.2 67.3 54.9 12.5 15.2 14.9 12.4 11.0 13.5 15.5 13.6 16.8 17.2 14.0 21.2 35.6 64.1 113.1 21.5 93.0 31.7 45.7 49.0 48.3 19.1 48.9 44.2 38.5 38.6 59.8 49.7 27.1 101.0 54.9 59.6 160.4 47.8 43.6 51.1 42.3 48.7 31.7 98.4 18.8 44.8 137.7 57.7 52.0 66.9 130.8 47.9 139.9 41.4 151.9 16.8 19.9 54.4 34.6 174.6 47.2 16.0 60.9 88.2 26.6 31.9 68.4 66.3 55.6 24.6 20.3 37.2 58.3 51.6 96.7 49.2 100.0 271.5 52.0 19.8 19.7 50.7 39.6 19.1 44.6 83.5 32.4 78.5 53.0 66.5 100.1 57.4 SNX7 ENSG00000162627 "Sorting nexin 7" Q9UNH6 1 98661701-98760500 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037419 Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "Cell Junctions" "HPA037419: AB_10671754" "unprognostic (3.19e-1)" "unprognostic (2.18e-1)" "prognostic favorable (5.10e-5)" "unprognostic (2.84e-2)" "unprognostic (1.14e-1)" "unprognostic (2.82e-2)" "prognostic unfavorable (9.59e-7)" "unprognostic (1.53e-2)" "unprognostic (2.64e-1)" "unprognostic (1.41e-2)" "unprognostic (1.19e-3)" "unprognostic (1.88e-1)" "unprognostic (7.95e-3)" "unprognostic (1.68e-1)" "unprognostic (1.45e-1)" "unprognostic (8.65e-2)" "unprognostic (1.77e-1)" 19.5 13.8 10.2 7.5 9.5 0.1 17.1 8.6 9.9 20.6 7.5 30.1 23.5 19.4 12.6 16.6 15.6 16.2 22.1 10.1 13.6 24.9 12.8 11.3 3.4 11.6 12.7 11.3 13.7 15.1 8.4 16.8 10.7 14.3 29.9 3.2 14.1 16.4 5.4 11.0 22.9 25.8 9.8 5.4 16.9 15.7 16.4 3.6 12.2 10.9 4.7 20.3 14.3 10.8 50.4 26.7 15.8 21.6 54.9 86.3 8.9 31.3 56.6 45.9 59.2 15.6 18.4 0.0 39.7 77.1 37.7 14.2 16.8 44.4 45.5 0.2 32.3 0.0 41.2 27.1 32.4 0.0 0.0 43.5 46.8 37.8 16.5 51.7 64.9 0.7 0.0 0.1 73.3 10.3 0.4 0.0 15.2 20.0 38.0 0.0 35.4 0.1 45.3 39.8 7.8 93.5 41.6 39.0 23.7 26.2 0.0 1.8 44.9 44.7 24.8 35.0 64.2 0.0 0.1 0.1 63.3 0.0 22.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.2 9.5 8.6 9.9 10.1 13.6 11.6 12.7 10.7 9.8 16.4 10.8 14.1 19.2 6.7 23.2 0.5 14.7 44.7 60.0 9.6 0.7 16.3 23.0 49.1 27.1 22.0 23.9 0.0 34.1 0.1 37.4 37.2 47.0 19.3 29.4 33.0 17.8 21.0 0.0 18.3 80.7 33.8 37.9 20.9 19.6 1.3 22.4 17.9 12.0 12.9 3.3 25.7 26.6 48.8 2.1 13.7 23.9 34.2 5.0 35.6 12.2 37.2 12.8 0.0 58.8 8.2 56.8 25.7 52.6 0.1 28.5 34.1 69.0 27.2 0.8 32.9 23.1 36.2 15.5 10.5 27.1 16.3 14.1 1.6 30.2 49.1 57.3 SNX8 Mvp1 ENSG00000106266 "Sorting nexin 8" Q9Y5X2 7 2251770-2354318 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 108.9;Late spermatids: 358.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 100.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA057296, HPA060194" Approved Supported Vesicles NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA057296: AB_2683401, HPA060194: AB_2684219" "unprognostic (2.22e-2)" "unprognostic (3.38e-1)" "unprognostic (9.85e-3)" "unprognostic (1.39e-1)" "unprognostic (2.08e-2)" "unprognostic (9.32e-2)" "prognostic unfavorable (8.47e-6)" "unprognostic (5.23e-2)" "unprognostic (1.91e-3)" "unprognostic (1.54e-2)" "unprognostic (3.06e-1)" "unprognostic (6.01e-2)" "unprognostic (1.54e-1)" "unprognostic (5.10e-2)" "unprognostic (4.83e-2)" "unprognostic (1.12e-2)" "unprognostic (1.35e-1)" 15.4 6.8 13.7 11.3 14.1 10.9 12.4 11.8 11.4 7.0 10.9 7.7 10.6 6.9 3.1 10.2 7.0 9.8 12.8 12.9 11.3 7.3 7.2 9.7 21.5 15.1 13.0 7.5 7.5 5.9 5.4 9.3 13.3 4.3 6.8 5.7 7.8 3.0 11.0 10.2 9.5 5.6 12.9 32.7 6.9 23.2 15.1 7.9 8.3 7.5 17.7 8.5 5.7 14.9 40.3 38.7 15.6 21.8 21.3 20.5 36.7 19.2 28.4 31.8 39.2 27.3 30.6 23.4 7.7 22.8 100.9 10.6 13.6 10.5 16.1 5.9 12.8 13.0 15.5 22.9 53.9 12.7 20.8 41.4 12.1 39.0 15.0 8.5 12.1 18.3 26.0 26.9 26.4 26.4 4.3 13.5 28.4 22.4 19.0 20.6 32.2 10.7 7.5 18.8 7.5 19.7 17.4 47.8 27.3 17.0 35.5 27.4 18.5 26.6 69.7 44.0 25.4 17.5 22.9 21.9 26.4 16.9 73.6 11.8 15.4 5.1 2.9 17.2 2.1 26.1 2.1 2.9 21.8 30.6 2.0 2.4 2.6 2.2 17.8 5.4 3.4 8.7 13.7 14.1 11.8 11.4 12.9 11.3 15.1 13.0 13.3 12.9 15.1 14.9 7.4 6.4 9.4 3.9 35.7 5.2 7.8 6.1 2.8 10.0 12.3 10.4 12.4 10.0 4.8 3.7 8.4 16.7 7.7 10.5 13.7 21.0 108.9 3.3 12.8 13.0 6.0 26.3 5.0 30.0 15.4 10.3 10.7 4.5 12.6 8.2 45.3 8.8 78.1 21.9 7.8 10.9 6.1 35.2 75.2 358.9 12.2 36.7 14.2 6.5 41.9 7.8 7.2 2.5 9.1 26.9 7.9 13.2 12.9 8.8 12.5 14.9 5.5 12.5 0.0 5.3 9.6 10.6 22.9 5.7 6.1 43.4 6.3 29.6 9.7 9.2 SOBP FLJ10159 ENSG00000112320 "Sine oculis binding protein homolog" A7XYQ1 6 107490106-107661306 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 175.3;Excitatory neurons: 260.1;Granulosa cells: 149.3;Inhibitory neurons: 287.7;Oligodendrocyte precursor cells: 263.9;Oligodendrocytes: 278.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.3" "Lineage enriched" "Detected in single" 13 "B-cells: 1.3" "Cell line enhanced" "Detected in many" "AF22: 10.5;AN3-CA: 13.9;ASC diff: 12.9;HDLM-2: 9.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029242 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 47: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm Vesicles "HPA029242: AB_10603340" "unprognostic (7.11e-2)" "unprognostic (1.35e-3)" "unprognostic (9.01e-2)" "unprognostic (2.04e-3)" "unprognostic (3.09e-1)" "unprognostic (1.12e-1)" "unprognostic (3.80e-2)" "unprognostic (5.63e-2)" "unprognostic (9.84e-2)" "unprognostic (5.35e-3)" "prognostic favorable (1.55e-5)" "unprognostic (6.64e-2)" "unprognostic (2.00e-3)" "unprognostic (5.41e-2)" "unprognostic (2.12e-1)" "unprognostic (1.39e-1)" "unprognostic (1.95e-3)" 4.5 6.6 12.4 1.7 14.5 0.0 3.4 9.0 16.9 6.2 0.4 14.6 1.2 5.6 2.0 2.0 4.3 2.7 10.9 15.3 8.2 3.4 1.6 2.4 0.9 6.7 9.1 10.8 1.4 3.1 9.4 2.3 6.2 8.2 1.3 5.3 10.4 2.6 16.7 1.2 3.2 3.9 6.5 1.9 4.8 4.2 9.5 2.7 4.2 5.9 1.1 11.9 4.4 11.4 0.0 0.3 10.5 13.9 12.9 4.9 1.2 0.0 0.0 0.3 0.6 0.0 0.0 5.7 0.3 0.0 0.9 0.0 7.0 0.2 0.2 9.0 6.8 0.6 0.0 6.8 1.6 3.0 0.5 5.2 0.0 5.1 0.0 1.1 4.2 2.6 0.0 0.3 0.0 2.9 1.3 0.3 2.5 0.3 0.9 3.1 1.3 0.0 0.0 0.2 3.3 5.6 1.2 0.0 0.1 0.4 0.4 2.0 0.0 3.3 1.1 5.7 0.5 2.6 0.5 3.5 0.1 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 14.5 9.0 16.9 15.3 8.2 6.7 9.1 6.2 6.5 9.5 11.4 6.0 3.2 9.8 175.3 9.2 0.5 10.3 11.4 3.4 40.4 0.5 7.4 19.4 17.2 6.1 23.9 0.0 0.2 1.8 0.2 0.0 2.5 96.2 0.6 15.8 4.4 10.8 5.3 260.1 0.2 0.7 23.6 3.1 0.4 0.0 149.3 5.3 1.4 3.0 92.5 287.7 0.1 4.1 9.6 4.1 61.4 45.1 1.8 3.6 51.5 0.1 7.6 0.0 263.9 278.8 0.4 0.0 48.9 0.2 9.3 0.0 11.9 10.9 10.1 26.3 42.8 21.0 61.2 5.6 0.6 0.9 0.1 1.3 13.3 0.2 1.0 SOHLH2 "bHLHe81, FLJ20449, SPATA28, TEB1" ENSG00000120669 "Spermatogenesis and oogenesis specific basic helix-loop-helix 2" Q9NX45 13 36168217-36214588 "Predicted intracellular proteins, Transcription factors" "Differentiation, Oogenesis, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 27.5" "Group enriched" "Detected in some" 5 "Early spermatids: 55.5;Extravillous trophoblasts: 19.5;Late spermatids: 77.0;Spermatocytes: 22.5;Spermatogonia: 33.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 8.3;HL-60: 11.2;Karpas-707: 12.1;NB-4: 16.1;U-266/84: 16.5" HPA029182 Uncertain Vesicles NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Vesicles "HPA029182: AB_10602409" "unprognostic (1.00e-1)" "unprognostic (1.65e-1)" "unprognostic (1.99e-1)" "unprognostic (2.99e-2)" "unprognostic (2.54e-2)" "unprognostic (3.01e-2)" "unprognostic (2.95e-1)" "unprognostic (7.88e-2)" "unprognostic (2.12e-1)" "unprognostic (1.39e-1)" "unprognostic (5.53e-3)" "unprognostic (2.10e-1)" "unprognostic (8.56e-2)" "unprognostic (7.44e-2)" "unprognostic (5.93e-2)" 0.5 0.4 0.9 0.1 0.9 0.8 0.5 0.5 1.1 0.3 0.2 2.0 0.3 0.4 2.1 0.4 0.3 0.3 1.0 0.9 1.9 0.7 0.0 0.1 0.3 0.8 0.7 0.3 0.0 1.4 0.3 1.1 0.7 1.8 0.1 1.2 0.2 1.3 0.6 0.3 0.2 0.5 0.8 0.1 0.3 27.5 1.1 0.3 0.5 5.3 0.0 0.9 0.1 1.1 8.3 0.2 0.8 0.0 0.7 1.3 4.8 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.5 0.2 0.2 0.0 0.1 0.0 0.1 1.9 0.1 0.0 0.1 11.2 0.0 2.2 0.6 0.0 0.0 0.4 1.0 0.3 0.4 12.1 2.5 0.1 0.0 16.1 0.2 0.0 0.0 0.2 0.2 0.9 1.2 0.8 0.2 1.5 0.0 0.0 0.0 2.9 0.1 0.7 0.0 0.0 0.9 0.6 0.5 1.6 16.5 0.2 0.9 5.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 0.5 1.1 0.9 1.9 0.8 0.7 0.7 0.8 1.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.1 0.7 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 55.5 0.1 0.2 0.1 0.0 0.0 0.0 0.0 19.5 0.1 0.0 0.3 0.0 0.8 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 77.0 0.6 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 2.1 0.0 0.3 0.0 0.0 0.1 22.5 33.5 0.0 0.1 3.4 0.0 0.1 0.0 0.1 SORCS2 KIAA1329 ENSG00000184985 "Sortilin related VPS10 domain containing receptor 2" Q96PQ0 4 7192538-7742836 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.9" "Cell type enhanced" "Detected in many" "Astrocytes: 107.1;Bipolar cells: 70.3;Excitatory neurons: 41.4;Muller glia cells: 33.0;Oligodendrocytes: 76.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 7.6;HaCaT: 19.6;HMC-1: 14.5;RPMI-8226: 9.1;SiHa: 14.1;THP-1: 8.4;U-937: 8.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071818 Approved Vesicles,Cytosol NA NA "Cluster 45: Intestine - Brush border" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Cytosol" "HPA071818: " "unprognostic (1.38e-1)" "unprognostic (6.32e-2)" "unprognostic (1.91e-2)" "unprognostic (4.37e-2)" "unprognostic (4.91e-3)" "unprognostic (1.82e-2)" "unprognostic (4.60e-2)" "unprognostic (1.14e-2)" "unprognostic (1.49e-3)" "prognostic unfavorable (3.55e-4)" "unprognostic (1.52e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (2.17e-3)" "unprognostic (5.37e-2)" "unprognostic (2.09e-1)" "unprognostic (7.27e-3)" 2.4 1.1 13.4 3.4 18.3 1.7 1.6 11.6 15.9 8.5 0.0 4.5 1.4 4.7 3.8 2.2 3.3 3.6 2.0 12.1 11.3 9.0 4.6 4.4 0.8 18.6 17.6 5.8 0.7 0.0 2.7 0.2 14.7 5.2 1.1 12.9 1.0 2.4 1.1 1.8 2.6 6.2 11.3 0.4 1.6 1.6 14.1 3.1 3.1 1.2 1.2 3.0 3.7 22.9 0.8 1.1 1.3 0.2 0.1 0.0 0.0 0.2 0.1 1.6 0.4 0.2 0.6 0.0 7.6 5.0 1.3 19.6 0.0 0.0 0.3 0.0 0.0 0.0 2.8 0.3 0.2 0.0 14.5 0.2 4.3 6.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 0.1 0.0 0.0 0.4 0.0 0.9 0.0 1.6 9.1 0.2 0.0 0.8 0.7 14.1 0.0 0.0 0.8 0.0 8.4 0.0 4.9 1.4 0.0 0.1 0.0 0.0 0.0 1.6 8.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 18.3 11.6 15.9 12.1 11.3 18.6 17.6 14.7 11.3 14.1 22.9 0.1 3.2 11.3 107.1 0.0 0.1 0.3 4.6 0.0 70.3 0.1 2.4 2.0 0.0 6.9 5.5 0.0 0.0 0.3 0.0 0.0 0.2 2.2 0.4 0.4 0.3 0.0 0.0 41.4 0.0 0.0 5.0 0.0 0.9 0.0 5.4 0.4 1.6 0.2 1.7 24.3 0.0 2.0 0.3 0.0 11.6 12.8 0.4 1.8 8.4 0.1 33.0 1.0 8.0 76.2 1.1 0.0 7.9 0.1 0.4 0.4 1.4 2.0 2.7 0.0 0.9 1.0 0.1 0.3 0.0 0.4 0.0 0.3 1.5 0.0 0.6 SOS2 ENSG00000100485 "SOS Ras/Rho guanine nucleotide exchange factor 2" Q07890 14 50117130-50231578 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.0" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004577, HPA047368, HPA052689" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm Vesicles "CAB004577: AB_628270, HPA047368: AB_2680014, HPA052689: AB_2681917" "unprognostic (7.99e-2)" "unprognostic (6.17e-2)" "unprognostic (7.80e-2)" "unprognostic (4.93e-2)" "unprognostic (2.81e-2)" "unprognostic (7.64e-2)" "unprognostic (1.56e-1)" "unprognostic (3.08e-1)" "unprognostic (2.01e-1)" "unprognostic (3.88e-1)" "unprognostic (9.99e-2)" "unprognostic (8.21e-2)" "prognostic favorable (8.48e-8)" "unprognostic (2.47e-2)" "unprognostic (1.91e-1)" "unprognostic (1.01e-1)" "unprognostic (6.57e-2)" 23.8 14.9 15.3 15.3 21.4 39.5 17.9 18.2 19.5 14.3 13.5 17.4 21.5 15.2 22.4 16.4 12.7 12.9 21.5 14.0 16.8 24.5 13.2 15.8 14.4 19.7 18.6 15.3 15.9 39.3 9.1 17.0 19.1 15.4 17.3 14.0 14.5 18.7 57.6 17.9 24.5 18.0 16.8 17.8 13.7 27.9 19.6 16.5 25.1 63.8 13.5 14.8 10.5 23.9 15.3 11.1 22.1 14.9 16.6 18.0 10.4 13.5 14.8 10.0 12.5 4.9 19.8 16.0 11.9 17.3 17.3 13.8 12.1 10.2 17.7 26.9 4.4 16.1 8.5 8.5 18.3 19.1 16.6 18.8 24.6 9.3 21.6 25.2 21.8 13.1 12.5 39.0 24.2 12.7 15.9 15.1 6.9 11.4 9.6 17.0 30.8 12.1 16.1 14.4 16.0 18.7 15.0 17.5 17.8 15.9 19.4 23.0 24.1 27.3 17.8 12.5 8.9 27.3 31.7 19.6 7.1 10.5 16.4 8.0 1.1 2.8 1.1 0.9 0.9 0.6 0.7 0.8 0.8 0.7 0.8 0.7 4.6 1.7 2.0 1.4 0.0 0.4 15.3 21.4 18.2 19.5 14.0 16.8 19.7 18.6 19.1 16.8 19.6 23.9 34.1 9.6 26.3 59.4 18.4 35.7 20.9 10.5 10.2 17.2 23.8 15.6 43.7 17.2 18.2 18.4 16.7 8.2 46.3 36.0 7.9 11.3 17.0 18.7 30.4 23.5 20.4 6.3 71.5 10.7 8.0 22.2 12.8 29.8 20.3 37.4 22.9 13.8 8.8 25.2 89.6 18.5 12.2 33.3 17.5 8.6 12.5 29.0 17.8 80.6 29.0 17.6 21.6 100.5 104.8 14.5 24.6 13.5 28.6 27.3 28.6 15.8 14.3 22.5 19.7 43.4 30.8 54.3 12.3 17.7 39.6 13.0 24.2 17.4 14.9 30.6 SOSTDC1 "DAND7, DKFZp564D206, USAG1" ENSG00000171243 "Sclerostin domain containing 1" Q6X4U4 7 16461481-16530580 "Predicted secreted proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 111.3;stomach 1: 60.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 68.5;Distal tubular cells: 29.4;Gastric mucus-secreting cells: 76.5;Horizontal cells: 30.3;Ionocytes: 128.1;Melanocytes: 32.0" "Cancer enhanced" "Detected in many" "renal cancer: 25.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.9;EFO-21: 12.7;HEL: 4.8;NTERA-2: 4.9;RPTEC TERT1: 23.5" "Group enriched" "Detected in many" 5 "basal ganglia: 9.2;hippocampal formation: 18.4;pons and medulla: 15.1;thalamus: 11.9" "Low region specificity" "Detected in many" HPA042856 Uncertain "Nucleoli,Nucleoli rim,Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 30: Mammary glandular cells - Lactation" "Golgi apparatus" "Nucleoli, Nucleoli rim, Vesicles" "HPA042856: " "unprognostic (2.08e-2)" "unprognostic (2.49e-1)" "unprognostic (1.14e-1)" "unprognostic (6.17e-3)" "unprognostic (5.59e-3)" "unprognostic (4.13e-2)" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (1.41e-2)" "prognostic favorable (8.69e-4)" "unprognostic (2.59e-1)" "unprognostic (2.62e-1)" "prognostic favorable (3.22e-5)" "unprognostic (7.01e-2)" "unprognostic (1.23e-1)" "unprognostic (3.50e-2)" "prognostic unfavorable (8.72e-4)" 0.2 0.5 1.3 0.9 2.7 0.1 17.9 1.7 3.4 2.6 111.3 10.9 11.6 4.7 0.3 3.7 5.0 0.3 3.1 3.7 0.3 22.3 0.0 39.2 0.1 0.7 0.9 1.1 0.6 0.6 2.4 0.0 0.1 1.8 15.0 3.0 15.6 3.5 0.1 16.8 8.6 1.1 0.2 0.1 60.4 1.9 2.2 0.1 8.6 0.9 3.9 1.4 3.5 1.8 0.0 0.0 7.9 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 12.7 0.0 0.0 0.3 0.4 0.0 0.0 0.1 2.6 4.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.3 0.1 0.0 0.1 0.7 0.9 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.7 1.7 3.4 3.7 0.3 0.7 0.9 0.1 0.2 2.2 1.8 0.4 0.0 0.0 0.0 0.2 5.6 4.3 2.1 9.1 0.6 68.5 17.8 3.8 0.0 2.0 14.7 0.0 0.0 0.4 1.2 29.4 0.0 19.7 1.0 0.1 2.9 2.4 0.0 0.0 0.0 0.0 3.9 76.5 1.5 0.0 0.0 0.4 0.1 0.0 30.3 0.0 0.2 128.1 0.0 1.2 13.0 7.2 0.4 32.0 0.0 0.0 14.2 0.0 0.0 0.0 0.4 2.2 2.6 0.4 1.1 0.0 21.8 0.0 0.7 0.0 0.1 0.3 3.4 1.2 14.1 7.2 0.0 0.9 0.0 2.3 1.5 SOX15 "SOX20, SOX26, SOX27" ENSG00000129194 "SRY-box transcription factor 15" O60248 17 7588178-7590094 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 87.4;skin 1: 48.2" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 209.2;Basal squamous epithelial cells: 447.3;Squamous epithelial cells: 388.1;Suprabasal keratinocytes: 169.9" "Cancer enhanced" "Detected in many" "testis cancer: 67.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 6.7;non-classical monocyte: 10.6" "Lineage enriched" "Detected in many" 5 "monocytes: 10.6" "Group enriched" "Detected in many" 8 "A-431: 130.6;HaCaT: 142.1;HBEC3-KT: 57.8;hTCEpi: 56.6" "Not detected" "Not detected" "HPA067196, HPA074049" Enhanced Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Vesicles" Yes NA "Cluster 51: Monocytes - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Nucleoli, Golgi apparatus, Vesicles" "HPA067196: AB_2685802, HPA074049: AB_2686656" "unprognostic (5.79e-3)" "unprognostic (6.65e-2)" "unprognostic (1.40e-2)" "unprognostic (2.58e-2)" "unprognostic (2.72e-1)" "unprognostic (1.60e-1)" "unprognostic (6.02e-2)" "unprognostic (2.81e-2)" "unprognostic (5.00e-2)" "unprognostic (8.50e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (8.61e-3)" "unprognostic (1.03e-1)" "unprognostic (1.96e-1)" "unprognostic (2.95e-2)" "unprognostic (2.97e-1)" 2.2 0.9 15.0 0.8 14.6 2.7 3.4 17.4 23.3 21.1 11.8 12.4 0.7 8.2 1.7 87.4 11.0 1.0 8.6 14.5 15.3 1.7 1.3 1.5 0.5 14.3 15.0 15.3 1.0 0.2 7.9 0.3 14.1 12.1 0.5 5.0 14.6 7.1 2.3 48.2 3.5 1.3 14.5 1.1 4.7 2.6 14.7 1.0 2.3 1.8 2.8 10.4 32.7 15.0 130.6 3.2 1.8 1.0 0.1 0.3 9.6 1.4 0.5 1.1 1.7 2.5 0.8 0.4 1.2 0.1 0.4 142.1 0.1 57.8 0.4 3.3 3.9 0.5 1.7 0.5 0.2 0.3 2.6 0.0 56.6 0.7 11.9 3.6 0.0 2.6 2.9 0.8 0.2 0.9 0.6 1.5 3.6 0.3 0.7 1.6 1.8 1.0 2.7 0.7 0.8 2.2 1.5 0.5 0.7 5.5 1.1 1.0 1.6 1.3 2.3 1.6 4.4 0.9 1.5 1.6 4.4 1.7 3.2 0.1 2.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 10.6 1.0 0.0 0.4 15.0 14.6 17.4 23.3 14.5 15.3 14.3 15.0 14.1 14.5 14.7 15.0 0.8 0.0 0.0 2.6 0.1 209.2 51.8 72.7 447.3 13.6 6.3 13.0 4.7 0.0 20.6 1.8 14.6 1.7 0.7 0.5 1.9 0.1 0.2 0.4 4.9 3.1 1.2 0.0 8.1 0.5 2.0 10.4 0.0 0.4 0.0 1.3 1.4 0.0 0.4 10.1 7.7 0.4 10.2 1.2 19.3 1.1 31.4 0.9 26.6 1.0 1.2 50.0 0.0 4.0 2.4 0.5 0.1 36.9 4.9 21.2 0.3 0.2 16.2 9.4 32.9 7.8 7.1 0.7 10.9 388.1 169.9 1.1 1.1 0.6 0.8 73.8 SOX30 ENSG00000039600 "SRY-box transcription factor 30" O94993 5 157625679-157671480 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 85 "testis: 80.6" "Cell type enriched" "Detected in some" 4 "Early spermatids: 351.1" "Cancer enhanced" "Detected in some" "cervical cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.9;CACO-2: 1.3;HDLM-2: 4.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006159, CAB009382" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 36: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" Cytosol "CAB009382: AB_2195963, HPA006159: AB_1080062" "unprognostic (3.51e-2)" "unprognostic (4.72e-2)" "unprognostic (7.31e-2)" "unprognostic (4.70e-4)" "unprognostic (2.53e-2)" "unprognostic (6.12e-2)" "unprognostic (4.47e-2)" "unprognostic (2.22e-2)" "unprognostic (5.33e-2)" "unprognostic (1.36e-1)" "unprognostic (4.73e-2)" "unprognostic (7.85e-2)" "unprognostic (4.64e-4)" "unprognostic (5.88e-2)" "unprognostic (1.64e-1)" "unprognostic (3.72e-2)" "unprognostic (3.45e-1)" 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.3 0.7 0.1 0.0 0.1 0.9 0.1 0.1 0.1 0.3 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.1 0.2 0.1 80.6 0.4 0.7 0.0 0.0 0.1 0.1 0.0 0.2 1.9 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 1.3 0.8 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 4.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.3 0.1 0.3 0.1 0.0 0.0 0.2 0.3 0.2 0.0 0.3 0.2 0.2 0.0 0.0 0.0 0.5 0.3 0.1 0.1 0.1 0.1 0.2 0.1 0.3 0.1 0.1 0.2 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.6 0.0 0.0 0.1 0.0 0.6 0.0 0.0 351.1 0.5 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 71.4 1.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 42.8 11.7 0.0 0.0 0.0 0.1 0.3 0.0 0.0 SP2 KIAA0048 ENSG00000167182 "Sp2 transcription factor" Q02086 17 47896150-47928957 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003357, CAB010245" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 59: Non-specific - Transcription" Nucleoplasm Vesicles "CAB010245: AB_2121523, HPA003357: AB_1080070" "unprognostic (1.23e-1)" "unprognostic (1.66e-2)" "unprognostic (6.30e-3)" "unprognostic (5.85e-2)" "unprognostic (1.18e-1)" "unprognostic (6.91e-2)" "unprognostic (5.66e-2)" "unprognostic (2.46e-1)" "unprognostic (6.46e-2)" "unprognostic (2.52e-1)" "unprognostic (1.44e-1)" "unprognostic (5.39e-2)" "prognostic favorable (1.82e-5)" "unprognostic (5.34e-3)" "unprognostic (4.28e-2)" "unprognostic (3.37e-2)" "unprognostic (8.66e-2)" 14.8 10.7 9.4 16.6 11.6 19.4 15.4 16.1 11.5 12.9 6.9 14.3 14.9 14.7 12.0 17.2 15.1 11.5 18.3 9.6 10.1 12.5 8.7 14.9 20.6 12.4 10.4 15.1 16.0 23.5 9.8 13.6 11.1 13.5 13.3 10.5 16.2 12.5 32.2 14.8 15.6 12.8 8.3 17.7 13.0 17.8 11.8 25.3 18.1 26.6 15.0 13.6 13.4 13.3 33.5 37.3 25.1 21.6 12.1 11.2 26.1 19.3 13.6 19.0 17.1 41.3 16.2 28.6 17.4 24.7 20.1 25.6 17.5 16.4 19.9 41.7 26.6 28.5 25.6 22.3 11.2 26.4 34.2 16.4 19.1 22.4 21.1 13.5 18.5 26.3 31.8 47.5 18.8 45.0 64.6 16.8 11.8 29.6 24.9 30.8 34.4 18.6 13.4 52.1 26.8 31.4 16.9 17.9 20.0 15.0 26.7 25.6 30.3 34.8 18.1 24.2 30.1 42.3 50.6 26.0 19.0 18.5 29.2 13.6 6.1 9.9 8.3 7.0 7.3 4.9 6.3 7.9 4.9 5.6 7.1 7.4 11.3 9.7 6.6 4.5 7.2 6.6 9.4 11.6 16.1 11.5 9.6 10.1 12.4 10.4 11.1 8.3 11.8 13.3 14.6 9.6 19.5 5.2 17.7 6.2 15.8 7.8 12.0 9.0 9.8 9.9 9.7 12.8 8.3 11.0 0.0 10.7 11.3 16.4 15.6 7.0 9.8 8.1 6.2 11.6 15.6 25.2 5.2 7.6 9.2 9.4 8.6 10.7 13.3 5.5 8.2 7.5 8.9 11.8 4.8 9.0 14.2 10.9 8.2 10.5 10.5 14.2 8.8 6.5 11.7 12.1 17.5 9.0 9.9 7.3 13.2 3.4 12.7 11.0 8.6 8.1 10.2 6.5 6.6 12.6 12.5 9.8 6.3 9.6 7.5 20.5 14.8 5.3 7.9 17.0 SPA17 "CT22, SP17" ENSG00000064199 "Sperm autoantigenic protein 17" Q15506 11 124673844-124697518 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 231.3" "Cell type enhanced" "Detected in many" "Early spermatids: 1583.7;Endometrial ciliated cells: 371.2;Late spermatids: 2667.9;Respiratory ciliated cells: 368.6;Spermatocytes: 580.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037568 Enhanced Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 6: T47d - Mammary gland" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA037568: AB_10672905" "unprognostic (1.41e-2)" "unprognostic (3.49e-1)" "unprognostic (2.39e-3)" "prognostic favorable (1.03e-4)" "unprognostic (2.85e-1)" "unprognostic (1.56e-1)" "unprognostic (1.01e-4)" "unprognostic (2.64e-1)" "unprognostic (3.80e-2)" "unprognostic (4.56e-2)" "unprognostic (6.47e-2)" "unprognostic (8.54e-2)" "unprognostic (1.71e-3)" "unprognostic (6.78e-2)" "unprognostic (9.78e-3)" "unprognostic (8.52e-2)" "unprognostic (2.71e-1)" 3.2 4.2 2.6 1.1 2.8 1.6 3.8 2.4 2.6 4.4 9.0 5.4 1.4 4.4 10.5 5.0 24.5 2.3 4.5 2.8 3.1 11.6 2.1 7.7 1.0 4.6 4.9 1.6 4.3 4.7 13.5 0.9 4.1 4.3 3.2 1.0 3.5 2.1 1.2 2.6 3.0 1.6 3.8 1.8 4.0 231.3 3.3 2.6 8.9 0.2 1.4 3.2 3.0 3.3 4.1 5.4 12.6 4.3 4.2 6.4 4.7 3.8 8.4 5.4 4.4 1.4 11.5 2.8 2.2 6.7 4.3 3.4 4.9 8.0 7.3 2.6 3.6 3.6 0.8 2.4 2.3 1.0 1.6 2.6 4.8 7.9 4.1 4.2 4.5 5.7 5.5 2.2 12.4 5.5 0.5 0.2 4.7 8.3 4.3 3.8 1.5 0.1 12.8 3.1 6.6 5.8 9.1 2.7 1.8 4.6 17.1 3.1 3.2 4.8 3.8 2.8 4.5 1.4 0.9 1.1 5.0 0.9 5.1 0.5 0.3 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.4 0.0 0.1 0.0 0.1 0.1 0.6 0.1 0.0 0.2 2.6 2.8 2.4 2.6 2.8 3.1 4.6 4.9 4.1 3.8 3.3 3.3 5.9 3.2 12.6 3.6 0.9 2.7 4.7 26.9 1.8 2.6 6.2 6.5 2.1 17.2 54.2 20.2 4.2 6.7 2.3 13.0 19.6 29.2 1583.7 371.2 13.8 7.2 7.2 3.2 5.8 15.5 10.8 5.8 8.2 19.4 0.0 7.1 1.8 1.5 11.9 0.0 2.8 9.2 32.6 3.1 1.0 2667.9 28.0 6.6 1.8 1.9 2.6 8.1 0.0 1.0 0.7 12.7 10.0 18.0 1.4 2.9 6.3 47.0 368.6 1.2 13.1 6.2 10.5 580.0 63.6 4.9 2.3 2.7 2.6 8.4 10.4 5.6 SPANXA1 "CT11.1, NAP-X, SPAN-Xa, SPAN-Xb, SPANX" ENSG00000198021 "Sperm protein associated with the nucleus, X-linked, family member A1" Q9NS26 X 141583674-141585011 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "testis: 15.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "U-2 OS: 3.2" "HPA046423, HPA073647" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 9: U-2 OS - Unknown function" Nucleoplasm Vesicles "HPA046423: AB_2679660, HPA073647: AB_2732232" 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.2 0.2 0.2 0.1 0.3 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPANXA2 SPANX ENSG00000203926 "SPANX family member A2" Q9NS26 X 141589708-141590762 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 62 "testis: 20.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.5;GAMG: 1.3;PC-3: 1.3;U-2197: 1.5" "HPA046423, HPA073647" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 18: U-2197 - ECM organization" Nucleoplasm Vesicles "HPA046423: AB_2679660, HPA073647: AB_2732232" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPANXB1 "CT11.2, SPANXB2, SPANXF1, SPANXF2" ENSG00000227234 "SPANX family member B1" Q9NS25 X 141002594-141003706 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 81 "testis: 88.8" "Group enriched" "Detected in some" 160 "Early spermatids: 686.8;Late spermatids: 2015.4" "Group enriched" "Detected in some" 4 "breast cancer: 2.1;cervical cancer: 1.1;head and neck cancer: 2.1;lung cancer: 1.8;urothelial cancer: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 81.9;GAMG: 16.6;U-2 OS: 27.4" "HPA046423, HPA073647" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" Nucleoplasm Vesicles "HPA046423: AB_2679660, HPA073647: AB_2732232" "unprognostic (8.55e-2)" 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.8 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.3 81.9 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.3 0.0 16.6 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.3 0.0 0.2 0.1 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.1 27.4 1.9 0.7 0.4 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.2 0.1 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 686.8 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2015.4 6.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.2 0.0 0.0 6.6 0.0 0.1 8.4 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPANXC "CT11.3, CTp11" ENSG00000198573 "SPANX family member C" Q9NY87 X 141241463-141242517 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "testis: 31.0" "Group enriched" "Detected in some" 209 "Early spermatids: 468.6;Late spermatids: 1668.9" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.6" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "A-431: 11.8;U-2 OS: 6.2" "HPA046423, HPA073647" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm Vesicles "HPA046423: AB_2679660, HPA073647: AB_2732232" "unprognostic (3.56e-1)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 31.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 11.8 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 6.2 0.0 0.3 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.1 1.0 0.2 0.1 0.3 0.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 468.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1668.9 4.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPANXD "CT11.4, SPANXE" ENSG00000196406 "SPANX family member D" Q9BXN6 X 141697411-141698739 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 109 "testis: 23.2" "Group enriched" "Detected in some" 148 "Early spermatids: 491.4;Late spermatids: 1560.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "A-431: 1.2;U-2 OS: 3.9" "HPA046423, HPA073647" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm Vesicles "HPA046423: AB_2679660, HPA073647: AB_2732232" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 491.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1560.9 5.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPANXN4 "CT11.9, SPANX-N4" ENSG00000189326 "SPANX family member N4" Q5MJ08 X 143025918-143034702 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 59 "testis: 25.9" "Group enriched" "Detected in some" 165 "Early spermatids: 97.7;Late spermatids: 298.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045730, HPA059094" Uncertain Approved "Nuclear membrane,Vesicles,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "Nuclear membrane" "HPA045730: AB_10961036, HPA059094: " 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 97.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 298.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPARC "BM-40, ON, ONT" ENSG00000113140 "Secreted protein acidic and cysteine rich" P09486 5 151661096-151686975 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 2184.6" "Cell type enhanced" "Detected in many" "Adipocytes: 737.1;Endometrial stromal cells: 1209.0;Endothelial cells: 781.9;Fibroblasts: 1032.1;Peritubular cells: 1111.1;Sertoli cells: 2353.5;Smooth muscle cells: 1527.3;Theca cells: 987.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 10.4;classical monocyte: 8.7;neutrophil: 24.3" "Group enriched" "Detected in many" 7 "granulocytes: 24.3;monocytes: 8.7" "Cell line enhanced" "Detected in many" "ASC diff: 4911.5;BJ: 4101.8;fHDF/TERT166: 6492.5;WM-115: 4789.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002306, HPA002989, HPA003020" Supported Approved Vesicles "Secreted to blood" NA NA 8300000 130000000 "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "CAB002306: AB_563919, HPA002989: AB_1079532, HPA003020: AB_1079531" "unprognostic (3.34e-2)" "unprognostic (8.57e-2)" "unprognostic (1.31e-1)" "unprognostic (3.97e-1)" "unprognostic (7.01e-2)" "unprognostic (1.49e-1)" "unprognostic (2.05e-1)" "unprognostic (8.36e-3)" "unprognostic (5.27e-2)" "unprognostic (1.22e-1)" "unprognostic (4.09e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (3.53e-5)" "unprognostic (2.59e-3)" "unprognostic (1.17e-2)" "unprognostic (3.53e-1)" "unprognostic (4.93e-3)" 1661.2 406.4 578.0 436.4 922.0 32.4 528.6 733.1 339.2 837.2 297.8 355.6 110.5 538.9 112.7 307.7 271.4 1526.8 563.5 362.9 1554.2 176.1 158.5 498.0 232.1 1370.4 1251.5 348.2 119.2 273.1 111.4 2184.6 1224.8 227.1 185.2 36.4 113.1 378.0 258.2 286.1 157.4 1251.5 995.9 260.8 143.3 406.7 1135.4 70.9 294.1 473.5 131.6 829.5 249.0 1088.4 5.9 5.0 1196.5 57.5 4911.5 1596.0 112.6 4101.8 1336.6 1649.3 1693.8 5.5 4.2 2.0 953.7 6492.5 272.0 56.7 153.4 316.2 555.0 4.8 57.1 56.7 0.4 116.8 1441.6 2.9 5.4 2567.2 436.9 1233.8 170.8 1903.1 2315.1 13.5 53.7 44.6 944.1 0.4 4.7 35.5 556.2 0.4 4.4 2.9 1192.9 4.3 0.5 0.5 45.5 88.4 2.8 1.4 534.9 1922.1 4.7 138.2 2759.9 771.0 1195.2 350.2 1304.4 3.7 6.0 7.6 648.4 3.7 4789.0 10.4 8.7 2.7 1.0 0.3 0.0 0.1 0.0 0.1 2.3 0.2 0.3 0.0 24.3 0.0 0.1 1.9 0.0 123.9 578.0 922.0 733.1 339.2 362.9 1554.2 1370.4 1251.5 1224.8 995.9 1135.4 1088.4 737.1 83.3 27.5 7.2 6.8 164.8 25.7 23.8 28.5 85.7 11.2 100.5 43.6 5.7 18.8 16.5 2.1 115.4 2.8 0.1 0.0 4.6 14.2 41.6 1209.0 781.9 0.0 15.1 4.3 0.4 354.3 1032.1 9.7 31.5 12.0 146.5 668.6 9.9 108.2 1.7 2.9 0.0 0.0 50.0 175.7 46.8 319.3 92.0 234.7 38.4 10.7 13.6 3.1 21.6 37.3 5.5 0.0 1111.1 4.1 7.7 0.0 42.0 7.8 72.7 2353.5 510.4 1527.3 14.2 10.9 4.8 108.3 147.4 21.1 987.4 0.0 5.3 SPATA21 "spergen-2, spergen2" ENSG00000187144 "Spermatogenesis associated 21" Q7Z572 1 16387117-16437424 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "testis: 7.6" "Group enriched" "Detected in some" 8 "Early spermatids: 40.4;Late spermatids: 44.6" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.8" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.7" "Cell line enriched" "Detected in single" 7 "Hep G2: 5.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA032080 Approved Vesicles,Cytosol No NA "Cluster 38: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Vesicles, Cytosol" "HPA032080: " "unprognostic (3.09e-1)" "unprognostic (8.26e-2)" "unprognostic (5.39e-1)" "unprognostic (1.47e-1)" "unprognostic (2.37e-1)" "unprognostic (5.17e-3)" "unprognostic (1.16e-1)" "unprognostic (2.76e-2)" "unprognostic (1.33e-2)" "unprognostic (1.56e-1)" "unprognostic (5.33e-2)" "unprognostic (3.14e-1)" "unprognostic (2.74e-10)" "unprognostic (1.25e-1)" "unprognostic (1.88e-1)" "unprognostic (1.87e-1)" "unprognostic (9.71e-2)" 0.0 0.1 0.2 0.0 0.2 0.6 0.0 1.8 0.5 0.0 0.5 0.0 0.3 0.1 0.2 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.4 0.0 0.1 0.2 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.9 0.0 0.1 0.0 0.4 0.1 0.1 0.0 0.1 0.1 7.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.5 5.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.2 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.5 0.2 0.1 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.0 1.7 0.1 0.2 0.2 0.2 0.1 0.3 0.2 0.1 0.1 0.3 0.2 0.1 0.6 0.2 0.1 0.1 0.2 0.1 0.2 0.2 1.8 0.5 0.3 0.1 0.2 0.0 0.1 0.0 0.1 0.3 0.1 0.0 1.1 1.0 0.4 0.3 0.3 0.0 0.6 1.5 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.3 0.3 0.2 0.0 0.0 40.4 0.3 0.9 0.3 0.0 0.0 1.6 0.2 0.3 0.3 0.0 0.9 0.0 0.1 0.0 0.0 0.1 5.0 1.4 0.0 0.0 0.6 0.4 44.6 0.3 0.3 0.0 0.0 0.1 0.7 0.0 1.0 1.3 0.0 0.0 0.4 0.0 0.3 0.0 0.1 0.1 1.2 0.0 0.9 0.3 1.2 0.4 0.4 0.4 0.3 0.3 0.1 0.3 0.2 SPATA33 "C16orf55, FLJ31606" ENSG00000167523 "Spermatogenesis associated 33" Q96N06 16 89657740-89671272 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 9 "testis: 114.0" "Group enriched" "Detected in all" 8 "Early spermatids: 1778.0;Late spermatids: 4200.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA045648, HPA073096" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" Nucleoplasm Vesicles "HPA045648: AB_2679405, HPA073096: AB_2686570" "unprognostic (1.05e-2)" "prognostic favorable (1.06e-4)" "unprognostic (1.04e-1)" "unprognostic (1.03e-3)" "unprognostic (2.42e-1)" "unprognostic (1.58e-1)" "unprognostic (7.18e-3)" "unprognostic (1.37e-1)" "unprognostic (3.97e-1)" "unprognostic (3.63e-2)" "unprognostic (2.03e-3)" "unprognostic (8.82e-2)" "unprognostic (4.02e-2)" "unprognostic (4.52e-2)" "unprognostic (3.26e-1)" "unprognostic (2.04e-1)" "unprognostic (1.60e-1)" 3.6 4.2 7.0 2.8 7.0 3.4 4.3 6.1 8.9 5.1 9.1 5.2 5.0 4.5 8.9 5.3 12.6 2.8 4.0 7.6 6.6 11.8 6.2 5.9 2.4 6.7 7.1 3.2 5.1 3.6 9.7 1.8 6.7 6.4 2.9 6.7 4.3 2.5 2.0 4.3 9.2 2.4 5.5 5.8 5.0 114.0 6.8 3.6 8.3 1.2 2.9 4.3 4.8 6.7 11.1 11.8 13.4 5.5 3.5 3.1 4.9 7.8 2.5 10.6 4.7 11.5 10.6 1.2 3.8 5.0 8.0 15.1 6.2 3.7 8.5 2.2 9.7 2.0 17.4 16.1 1.5 2.3 4.5 3.1 5.1 7.9 3.2 4.0 2.3 11.0 12.6 1.9 7.1 14.7 7.4 6.6 7.3 7.3 9.3 14.3 7.4 4.0 6.2 3.9 13.2 7.0 17.9 3.0 4.4 6.3 13.5 3.3 2.8 7.8 10.7 6.9 5.9 4.4 7.1 4.4 8.1 14.5 3.5 2.4 1.1 2.1 1.6 1.3 2.2 2.3 1.7 2.2 0.9 0.9 1.8 1.4 1.4 3.2 1.0 2.0 1.2 1.4 7.0 7.0 6.1 8.9 7.6 6.6 6.7 7.1 6.7 5.5 6.8 6.7 14.7 6.4 9.7 4.6 10.3 7.1 8.6 16.4 8.0 18.2 14.9 14.7 6.6 15.7 13.5 29.5 64.6 4.1 10.2 16.0 23.5 15.9 1778.0 94.9 13.3 13.3 17.5 22.7 7.0 17.7 5.6 13.0 32.1 11.9 1.3 11.4 8.9 14.6 9.0 23.5 4.4 9.9 12.2 2.9 8.0 4200.3 30.4 9.5 17.8 3.7 5.8 17.0 16.5 1.0 5.1 14.2 18.9 23.7 11.1 6.7 35.6 33.4 97.8 82.5 13.1 11.8 11.4 348.5 101.2 13.5 7.1 1.4 12.8 13.9 17.1 5.5 SPATA6 "FLJ10007, SRF-1, SRF1" ENSG00000132122 "Spermatogenesis associated 6" Q9NWH7 1 48295373-48472208 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 50.1" "Group enriched" "Detected in many" 5 "Early spermatids: 1475.4;Late spermatids: 4697.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 5.9" "Group enriched" "Detected in many" 4 "granulocytes: 3.6;monocytes: 5.9" "Cell line enhanced" "Detected in many" "AN3-CA: 12.9;ASC TERT1: 20.9;HSkMC: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028234 Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" Nucleoplasm "HPA028234: AB_2672532" "unprognostic (1.36e-2)" "unprognostic (2.96e-2)" "unprognostic (3.38e-2)" "unprognostic (2.87e-2)" "unprognostic (3.22e-1)" "unprognostic (1.68e-1)" "unprognostic (1.77e-2)" "unprognostic (4.69e-3)" "unprognostic (2.40e-2)" "unprognostic (2.61e-2)" "unprognostic (8.41e-2)" "unprognostic (6.50e-2)" "unprognostic (3.41e-3)" "unprognostic (1.15e-1)" "unprognostic (1.01e-1)" "unprognostic (7.89e-2)" "unprognostic (5.71e-3)" 6.0 8.1 6.2 2.0 9.7 1.0 7.2 6.9 6.4 7.8 7.2 5.2 2.7 5.8 6.1 3.4 15.3 4.9 4.4 5.9 8.0 6.1 1.7 5.9 2.2 8.6 8.5 8.9 4.6 10.6 8.6 4.7 8.6 5.4 3.9 13.3 6.3 7.4 1.7 4.4 3.3 4.4 7.3 3.7 6.7 50.1 9.6 3.2 9.5 3.7 1.6 6.0 6.3 11.9 0.2 1.2 11.6 12.9 10.5 20.9 1.6 1.3 4.9 0.9 0.8 0.1 0.8 0.0 0.7 2.1 6.1 0.3 0.9 2.9 0.8 0.9 1.6 0.1 0.5 0.6 2.2 0.0 0.8 15.0 2.2 1.9 0.7 6.3 4.7 1.8 0.1 0.0 4.9 0.4 0.1 0.2 4.9 0.9 1.2 3.7 0.0 1.1 7.1 2.0 2.8 6.3 4.8 0.4 11.3 9.5 2.8 0.7 1.4 1.7 1.7 2.7 1.9 0.0 0.0 0.0 7.0 0.1 7.7 0.0 1.2 3.6 0.0 2.8 0.0 0.1 0.2 0.0 1.1 0.0 0.4 0.3 0.1 0.2 5.9 0.5 0.0 0.5 6.2 9.7 6.9 6.4 5.9 8.0 8.6 8.5 8.6 7.3 9.6 11.9 14.8 3.2 10.0 151.8 2.0 5.6 16.7 6.4 9.1 17.0 13.1 19.9 3.5 28.6 12.5 16.5 45.9 0.4 5.1 3.9 17.6 8.9 1475.4 77.3 18.9 10.5 9.6 2.1 43.9 10.2 0.6 29.8 35.2 9.0 16.5 5.0 16.1 2.4 5.1 32.0 35.0 5.7 12.2 17.9 9.2 4697.2 36.7 14.9 19.6 68.4 10.5 23.4 3.1 563.5 341.6 4.5 3.8 25.2 2.0 6.2 3.4 10.3 67.3 45.7 19.7 47.5 14.7 110.5 23.8 6.7 5.3 0.3 1.6 11.5 5.7 9.7 SPATC1L C21orf56 ENSG00000160284 "Spermatogenesis and centriole associated 1 like" Q9H0A9 21 46161148-46184476 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 48.9" "Group enriched" "Detected in many" 5 "Early spermatids: 208.9;Late spermatids: 472.3" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 4.2;basal ganglia: 3.7;cerebral cortex: 4.8;hippocampal formation: 2.9" "Immune cell enhanced" "Detected in many" "eosinophil: 36.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 37.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA018979, HPA019165, HPA029394" Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 71: Testis - DNA repair" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" "Vesicles, Plasma membrane, Cytosol" "HPA018979: AB_1845696, HPA019165: AB_1845697, HPA029394: AB_10601148" "unprognostic (1.46e-2)" "unprognostic (3.88e-2)" "unprognostic (3.95e-2)" "unprognostic (4.86e-2)" "unprognostic (6.36e-2)" "unprognostic (1.71e-1)" "unprognostic (4.45e-3)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "unprognostic (1.27e-1)" "prognostic favorable (2.16e-4)" "unprognostic (5.56e-2)" "unprognostic (2.35e-3)" "unprognostic (1.07e-1)" "unprognostic (1.47e-1)" "unprognostic (1.91e-2)" "unprognostic (2.58e-1)" 7.6 23.4 4.2 1.0 3.7 1.3 8.5 0.0 4.8 11.4 0.0 9.7 1.3 9.8 0.6 7.7 6.8 1.4 11.5 2.9 0.6 7.3 1.3 5.9 1.6 0.4 0.1 13.9 11.3 1.6 14.2 1.1 0.1 32.5 0.7 0.3 6.7 2.5 5.6 10.5 6.9 0.8 0.0 8.4 8.3 48.9 0.9 1.0 6.3 0.8 1.0 9.8 11.7 0.1 2.9 0.0 3.6 6.7 2.0 4.7 1.9 4.1 2.2 2.2 1.7 0.0 1.8 9.0 8.0 5.0 2.6 0.5 0.0 3.2 0.6 8.3 6.6 21.6 1.3 5.0 0.1 0.0 8.5 5.0 1.5 0.0 0.0 4.2 7.2 10.1 37.8 13.2 3.1 5.7 7.0 2.5 15.0 4.0 18.0 15.4 4.9 10.0 3.4 0.8 1.1 6.9 3.2 1.7 8.6 2.5 5.6 8.3 0.4 6.5 8.0 9.3 6.3 21.9 12.6 6.6 8.6 11.9 6.1 1.5 5.7 36.1 4.3 6.8 5.6 7.6 6.2 5.9 8.6 7.6 9.7 9.2 0.3 6.6 4.7 7.2 7.0 3.6 4.2 3.7 0.0 4.8 2.9 0.6 0.4 0.1 0.1 0.0 0.9 0.1 20.5 0.0 0.0 3.6 13.5 23.6 11.6 21.4 18.2 6.8 11.9 14.6 1.9 12.8 6.9 3.7 0.0 3.4 10.1 7.7 15.6 16.8 208.9 6.3 14.6 15.4 60.4 12.8 2.6 20.5 17.7 18.1 13.7 8.8 0.0 18.8 14.6 0.6 13.7 3.3 2.0 16.4 8.2 8.8 24.4 472.3 32.3 9.9 28.4 1.0 5.9 5.8 6.2 3.0 3.1 17.8 6.6 31.6 28.0 24.1 6.8 13.4 2.8 3.1 19.7 12.0 14.0 17.8 14.7 17.0 40.1 3.1 11.7 4.0 18.3 8.1 SPCS1 "HSPC033, SPC1, SPC12, YJR010C-A" ENSG00000114902 "Signal peptidase complex subunit 1" Q9Y6A9 3 52704955-52711148 "Metabolic proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1177.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046091, HPA055273" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 16: U-266 - Nucleosome" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA046091: AB_10959614, HPA055273: AB_2682768" "unprognostic (5.47e-2)" "unprognostic (4.04e-1)" "prognostic favorable (9.28e-4)" "unprognostic (5.93e-2)" "unprognostic (6.88e-2)" "unprognostic (1.10e-2)" "unprognostic (3.22e-1)" "unprognostic (1.60e-1)" "unprognostic (1.91e-1)" "unprognostic (5.56e-2)" "unprognostic (3.89e-1)" "unprognostic (1.15e-1)" "prognostic favorable (2.90e-4)" "unprognostic (5.96e-2)" "unprognostic (1.80e-1)" "unprognostic (3.58e-1)" "unprognostic (3.09e-2)" 95.3 154.7 75.1 64.1 76.6 61.3 100.5 80.7 101.1 97.4 88.7 110.1 94.8 101.0 110.8 117.0 92.1 48.4 119.7 75.4 83.9 137.3 172.8 87.8 71.2 82.3 80.5 91.1 231.2 89.5 141.1 59.4 82.1 96.3 84.7 124.6 145.2 79.1 142.2 109.0 103.9 53.0 81.7 105.6 151.1 153.2 81.4 66.6 113.2 49.7 87.1 103.0 94.7 84.9 114.6 102.2 113.4 139.3 164.9 134.4 157.2 157.6 144.5 139.4 128.4 108.1 171.0 114.6 65.7 145.4 142.5 110.2 109.9 142.5 149.1 154.3 115.8 138.6 169.2 164.6 175.1 213.3 229.1 104.7 190.5 148.5 174.4 130.5 117.4 147.5 118.8 418.0 151.8 105.5 168.8 207.2 195.8 317.2 203.9 67.9 95.7 608.6 232.7 148.3 73.6 157.4 148.7 178.1 224.2 102.4 188.1 248.1 106.2 127.3 119.1 226.3 192.1 406.2 654.1 169.8 196.5 209.4 169.8 292.7 129.9 258.2 131.1 137.0 155.1 202.0 158.5 144.2 143.9 149.3 146.8 152.1 100.1 119.6 152.5 620.5 177.1 253.8 75.1 76.6 80.7 101.1 75.4 83.9 82.3 80.5 82.1 81.7 81.4 84.9 172.5 64.1 104.2 23.8 282.3 156.5 227.9 470.7 136.1 465.4 289.0 351.0 148.7 221.6 283.6 310.8 118.9 373.5 488.1 195.2 361.9 353.8 597.8 286.4 180.8 157.6 167.7 143.9 27.1 339.4 399.8 181.9 119.8 181.5 211.6 138.7 131.4 301.8 311.0 102.6 34.4 291.3 325.5 202.9 189.9 1177.6 216.3 192.5 380.6 13.1 321.9 296.9 213.1 21.1 53.2 274.8 274.1 191.8 888.8 295.0 405.5 665.1 374.1 251.3 164.3 152.6 335.5 746.4 504.5 195.8 184.4 351.2 220.8 283.6 267.7 285.3 SPECC1 "CYTSB, FLJ36955, HCMOGT-1, NSP" ENSG00000128487 "Sperm antigen with calponin homology and coiled-coil domains 1" Q5M775 17 20008865-20319026 "Disease related genes, Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 47.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 217.1;Inhibitory neurons: 220.8;Microglial cells: 187.4;Oligodendrocytes: 317.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 42.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SiHa: 75.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021421, HPA021430, HPA061073" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" NA NA 9800 "Cluster 46: Basophils - DNA binding" "Cluster 65: Brain - Ion transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Vesicles" "Nucleoli fibrillar center, Cytosol" "HPA021421: AB_1857431, HPA021430: AB_1857432, HPA061073: " "unprognostic (1.13e-3)" "unprognostic (2.39e-1)" "unprognostic (1.98e-2)" "unprognostic (8.10e-3)" "unprognostic (8.32e-2)" "unprognostic (1.38e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (9.29e-2)" "unprognostic (5.81e-2)" "unprognostic (6.23e-3)" "unprognostic (2.65e-1)" "unprognostic (3.15e-1)" "unprognostic (6.86e-2)" "unprognostic (1.79e-1)" "unprognostic (1.40e-1)" "unprognostic (2.04e-1)" 12.5 9.6 30.8 7.3 35.1 23.6 9.2 24.1 43.7 6.1 22.3 15.1 9.8 12.8 4.7 9.2 8.3 14.8 5.0 41.4 21.4 4.7 1.2 5.7 5.3 32.8 25.8 16.6 4.8 3.3 6.4 3.6 24.5 6.1 10.0 6.1 6.2 5.0 5.1 3.6 10.5 9.5 21.0 13.5 10.3 22.8 41.1 3.0 5.2 2.8 5.2 4.6 4.3 47.3 26.2 37.3 15.7 7.2 14.7 6.9 29.1 10.0 12.4 12.4 21.4 67.6 17.1 1.5 45.3 11.4 24.3 21.1 10.7 33.4 3.7 12.8 18.5 14.5 34.4 10.5 4.9 1.3 5.6 10.6 36.9 10.2 24.9 46.8 0.0 4.4 1.0 15.1 10.4 24.0 0.3 5.3 14.5 17.0 6.3 11.8 49.5 23.6 32.2 11.4 7.1 6.9 75.7 35.6 13.9 62.2 26.3 9.1 0.3 0.5 21.1 0.9 30.8 5.4 11.7 0.9 19.1 12.6 6.5 42.1 15.8 33.0 2.2 8.4 3.2 1.8 1.5 3.4 26.6 1.4 1.0 1.4 11.1 13.0 7.9 4.6 0.6 5.5 30.8 35.1 24.1 43.7 41.4 21.4 32.8 25.8 24.5 21.0 41.1 47.3 28.7 22.4 14.7 170.4 5.7 5.5 12.5 22.0 10.8 7.4 5.8 4.7 10.3 7.2 21.1 18.4 68.8 5.5 10.2 56.8 9.8 30.9 100.0 40.1 44.1 13.1 7.7 82.5 217.1 36.3 11.5 18.6 34.1 64.1 116.4 29.5 3.9 0.2 22.0 0.0 220.8 54.8 12.2 12.4 15.9 54.5 5.0 29.0 21.4 187.4 84.7 13.6 11.3 125.2 317.8 67.7 24.7 44.8 7.0 19.7 25.2 3.6 18.1 31.4 59.2 7.3 81.3 73.8 68.9 5.9 2.6 2.2 10.0 87.8 27.4 21.5 SPEG "APEG1, BPEG, KIAA1297, MGC12676, MYLK6, SPEGalpha, SPEGbeta" ENSG00000072195 "Striated muscle enriched protein kinase" Q15772 2 219434843-219493629 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 174.8" "Cell type enhanced" "Detected in many" "Astrocytes: 45.7;Cardiomyocytes: 61.5;Late spermatids: 39.6;Sertoli cells: 46.0;Smooth muscle cells: 32.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 45.9;U-87 MG: 23.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018904 Enhanced Approved Vesicles NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "HPA018904: AB_1844924" "unprognostic (3.70e-1)" "unprognostic (1.23e-2)" "unprognostic (5.05e-3)" "unprognostic (2.45e-4)" "unprognostic (2.04e-2)" "unprognostic (4.65e-3)" "unprognostic (2.41e-2)" "unprognostic (1.12e-1)" "unprognostic (8.92e-3)" "unprognostic (2.29e-2)" "unprognostic (8.66e-4)" "unprognostic (1.06e-1)" "unprognostic (3.47e-9)" "unprognostic (1.14e-1)" "unprognostic (7.01e-2)" "unprognostic (5.95e-4)" "unprognostic (1.28e-3)" 16.1 6.8 16.8 7.7 18.7 0.0 15.3 15.5 20.7 75.5 9.7 174.8 5.3 89.5 6.2 15.6 70.0 7.3 48.5 19.8 14.5 4.1 1.3 8.7 0.6 16.1 15.8 21.9 3.4 4.4 34.3 4.5 14.6 58.8 3.8 1.0 10.0 25.5 118.0 7.8 31.9 23.1 15.3 2.4 48.1 5.4 15.3 0.5 5.9 21.7 0.2 87.7 42.1 15.6 6.1 0.5 3.1 4.9 1.6 4.7 1.8 13.1 8.5 8.6 6.4 4.5 1.9 0.0 4.5 9.7 4.3 7.2 2.5 3.1 3.4 0.0 1.7 0.0 6.1 0.3 2.1 0.0 0.5 13.2 4.6 7.8 1.9 45.9 0.0 3.2 3.5 0.0 6.1 1.6 0.1 18.8 6.5 0.0 2.4 2.8 7.0 1.1 8.5 0.0 3.4 15.1 0.6 0.0 0.3 14.3 0.3 0.2 0.0 20.6 21.3 2.4 21.1 0.4 0.0 0.2 23.3 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.8 18.7 15.5 20.7 19.8 14.5 16.1 15.8 14.6 15.3 15.3 15.6 2.4 0.0 2.2 45.7 0.4 3.2 6.0 1.3 2.8 5.3 10.3 14.6 61.5 4.3 0.1 1.8 2.1 0.6 1.4 4.1 0.0 1.5 21.8 0.9 3.6 2.2 6.7 2.7 20.5 1.2 0.9 10.0 3.6 1.3 0.0 1.0 5.7 3.1 1.1 5.0 20.9 4.1 0.0 5.6 1.9 39.6 10.5 1.6 3.6 4.7 1.4 8.4 0.0 5.0 1.0 0.2 3.2 18.8 0.9 6.5 8.5 4.3 0.1 0.9 46.0 17.1 32.4 11.6 3.7 0.2 1.4 1.4 1.2 0.4 3.5 5.3 SPESP1 SP-ESP ENSG00000258484 "Sperm equatorial segment protein 1" Q6UW49 15 68818221-68946811 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 73.2" "Group enriched" "Detected in many" 4 "Early spermatids: 400.4;Spermatocytes: 455.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+: 17.8;BJ hTERT+ SV40 Large T+ RasG12V: 18.6;HBF TERT88: 21.7;HMC-1: 13.4;OE19: 15.9;RPTEC TERT1: 26.8;SCLC-21H: 19.9;WM-115: 31.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA045936, HPA051040" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted in male reproductive system" NA NA 52000 "Cluster 46: Basophils - DNA binding" "Cluster 83: Testis - Spermatogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Vesicles" Cytosol "HPA045936: AB_2679504, HPA051040: AB_2681322" "unprognostic (1.14e-1)" "unprognostic (1.43e-1)" "unprognostic (1.73e-3)" "unprognostic (9.82e-2)" "unprognostic (1.59e-1)" "unprognostic (1.42e-2)" "unprognostic (1.06e-1)" "unprognostic (5.96e-2)" "unprognostic (2.79e-1)" "unprognostic (2.40e-1)" "unprognostic (8.99e-2)" "unprognostic (1.10e-2)" "unprognostic (1.16e-2)" "unprognostic (2.68e-2)" "unprognostic (1.15e-1)" "unprognostic (1.75e-1)" "unprognostic (9.67e-2)" 2.3 3.4 1.1 0.8 1.1 0.4 2.2 1.2 1.6 1.2 1.0 1.6 1.2 1.5 6.3 2.6 1.8 3.5 3.1 1.1 1.2 2.0 1.2 1.1 0.8 1.3 1.2 3.4 1.9 4.7 1.2 12.9 1.3 3.5 1.1 2.8 1.8 2.9 1.6 1.0 0.9 1.2 1.3 1.3 1.5 73.2 1.1 0.9 1.9 1.9 0.7 2.4 0.8 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 17.8 18.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 21.7 5.0 0.0 0.0 0.0 0.0 6.3 0.0 13.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 2.9 0.0 0.0 3.3 15.9 0.0 0.0 1.4 0.0 26.8 0.2 19.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 31.6 1.1 1.3 0.4 0.2 1.1 0.5 0.5 0.4 0.3 0.8 0.3 0.3 0.5 0.5 0.2 0.8 0.4 0.4 0.5 1.1 1.1 1.2 1.6 1.1 1.2 1.3 1.2 1.3 1.3 1.1 1.6 5.1 0.0 0.0 0.0 0.2 1.9 3.0 23.7 1.8 1.0 2.7 4.1 4.1 1.5 4.0 7.3 4.2 92.3 0.3 0.2 1.9 2.1 400.4 3.9 3.4 3.6 1.8 0.8 0.0 2.7 7.2 5.5 0.0 2.0 0.0 1.7 2.2 1.8 7.8 0.0 0.0 0.9 6.1 2.1 3.3 90.3 21.1 1.2 5.4 0.0 1.0 5.3 0.0 0.0 0.0 0.9 0.0 8.6 0.0 3.3 0.0 3.9 6.3 5.6 46.0 3.4 4.2 455.0 88.7 1.1 2.3 62.1 0.5 11.1 0.2 1.5 SPG21 "ABHD21, ACP33, BM-019, GL010, MAST" ENSG00000090487 "SPG21 abhydrolase domain containing, maspardin" Q9NZD8 15 64963022-64990310 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 181.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040407, HPA040436" Approved Supported Vesicles,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Cytosol" "HPA040407: AB_2676965, HPA040436: AB_10796454" "unprognostic (7.47e-2)" "unprognostic (2.94e-2)" "unprognostic (5.81e-2)" "unprognostic (2.98e-1)" "unprognostic (1.64e-1)" "unprognostic (5.40e-3)" "unprognostic (7.25e-2)" "unprognostic (1.43e-1)" "unprognostic (4.19e-2)" "unprognostic (8.07e-2)" "unprognostic (4.24e-3)" "unprognostic (1.15e-1)" "unprognostic (3.96e-1)" "unprognostic (1.55e-1)" "unprognostic (3.49e-1)" "unprognostic (2.57e-1)" "unprognostic (3.19e-1)" 56.6 61.7 48.4 50.8 54.1 69.4 68.8 51.5 52.9 60.4 66.0 61.6 52.1 60.2 150.1 46.1 73.4 54.7 54.4 47.8 50.3 85.3 113.1 61.9 56.9 52.1 50.2 55.3 54.7 72.1 47.1 66.3 52.7 49.8 59.3 38.6 45.7 59.0 74.3 58.5 46.6 64.5 51.1 52.6 60.1 35.0 52.6 57.7 83.1 42.4 58.8 61.2 47.8 59.4 87.0 127.0 62.8 119.5 158.7 155.7 78.0 52.8 179.7 103.2 119.8 57.4 131.1 99.1 80.6 124.8 153.1 113.3 182.1 124.5 97.8 41.0 58.5 85.7 81.7 104.0 200.7 82.2 72.7 107.0 139.3 82.1 154.2 100.7 125.6 112.2 72.7 78.3 127.8 124.1 75.8 71.5 69.6 193.9 66.3 78.2 67.3 174.6 107.1 103.6 76.7 68.6 62.7 131.4 124.9 123.3 89.9 140.9 61.5 87.1 90.6 125.4 80.6 55.6 101.8 58.2 112.8 215.1 75.1 9.9 138.2 15.5 14.1 84.2 13.1 39.0 13.8 14.7 76.9 37.6 19.9 10.9 181.4 15.7 69.8 25.1 17.5 52.3 48.4 54.1 51.5 52.9 47.8 50.3 52.1 50.2 52.7 51.1 52.6 59.4 29.4 9.6 56.3 11.1 67.7 74.9 81.8 70.6 66.6 16.2 62.7 39.4 32.1 61.5 51.5 71.7 37.5 202.9 33.6 42.7 137.0 97.1 6.0 32.9 36.9 56.9 64.8 54.3 13.1 74.1 92.2 67.5 46.9 34.3 28.5 37.5 38.2 121.6 153.9 20.2 13.7 58.2 61.1 158.7 145.4 13.2 86.6 128.5 80.0 16.9 123.2 24.8 64.9 5.5 19.6 62.3 93.5 89.9 66.2 145.2 121.1 202.3 57.9 18.9 39.5 93.4 39.5 35.4 51.3 75.4 82.8 186.5 46.5 35.5 69.5 123.5 SPINK4 "MGC133107, PEC-60" ENSG00000122711 "Serine peptidase inhibitor Kazal type 4" O60575 9 33218365-33248567 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "intestine: 980.5" "Cell type enriched" "Detected in some" 14 "Intestinal goblet cells: 8017.1" "Group enriched" "Detected in many" 20 "colorectal cancer: 237.5;pancreatic cancer: 269.7;stomach cancer: 111.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "basophil: 1.8" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.8" "Group enriched" "Detected in some" 12 "HMC-1: 175.7;OE19: 480.7" "Region enhanced" "Detected in single" "pons and medulla: 1.1" "Low region specificity" "Detected in single" HPA007286 Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" "Secreted to digestive system" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus, Vesicles" Nucleoplasm "HPA007286: AB_1080083" "unprognostic (3.49e-2)" "unprognostic (2.32e-1)" "prognostic favorable (8.85e-5)" "unprognostic (3.09e-4)" "unprognostic (1.49e-1)" "unprognostic (1.00e-1)" "unprognostic (9.66e-2)" "unprognostic (2.43e-1)" "unprognostic (1.24e-1)" "unprognostic (3.25e-1)" "unprognostic (2.42e-3)" 1.4 0.6 0.0 84.2 0.0 0.6 0.1 0.7 0.3 0.0 0.1 639.5 263.4 1.8 0.0 0.1 0.0 0.6 0.0 0.0 0.0 1.4 0.0 0.0 0.7 0.1 0.1 0.0 0.9 2.1 0.9 0.0 0.1 0.0 980.5 92.1 0.1 0.5 0.2 0.1 638.1 42.2 0.0 0.2 1.4 0.3 0.0 0.1 0.0 0.0 0.0 17.4 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.4 0.0 0.0 0.0 3.5 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 11.7 27.8 1.1 0.0 0.0 175.7 0.0 0.0 0.0 0.4 0.5 0.0 0.1 4.1 0.3 0.0 3.9 0.4 2.3 0.0 480.7 0.4 0.0 0.0 0.2 0.0 0.5 0.4 1.4 15.2 3.1 0.0 0.1 14.2 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.3 0.1 1.4 0.3 0.0 1.8 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 5.0 0.3 0.0 0.0 0.0 21.7 0.1 0.0 0.0 0.0 0.0 5.5 12.5 0.1 0.0 56.5 0.0 0.2 1.0 0.1 0.0 0.6 88.2 0.0 0.0 0.0 0.0 0.0 43.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8017.1 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 23.9 0.0 0.5 0.1 0.1 106.8 0.0 0.1 0.2 541.4 0.0 0.0 129.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.1 191.5 0.2 SPINK5 "DKFZp686K19184, FLJ21544, FLJ97536, FLJ97596, FLJ99794, LEKTI, LETKI, NETS, NS, VAKTI" ENSG00000133710 "Serine peptidase inhibitor Kazal type 5" Q9NQ38 5 148025683-148137382 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 338.5;esophagus: 1015.0;skin 1: 318.2;vagina: 582.6" "Cell type enriched" "Detected in many" 4 "Squamous epithelial cells: 1622.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 45.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 14.7;HeLa: 22.7;Karpas-707: 19.3;SuSa: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009067, HPA011351, CAB015347" Enhanced Enhanced Vesicles "Secreted in other tissues" NA NA 43000000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "CAB015347: AB_2196138, HPA009067: AB_1080084, HPA011351: AB_1857447" "unprognostic (9.66e-3)" "unprognostic (1.42e-2)" "unprognostic (2.41e-1)" "unprognostic (1.17e-1)" "unprognostic (3.25e-2)" "unprognostic (1.42e-3)" "unprognostic (2.45e-2)" "unprognostic (6.85e-2)" "unprognostic (1.16e-1)" "unprognostic (2.28e-2)" "unprognostic (4.92e-3)" "unprognostic (4.56e-1)" "unprognostic (2.44e-1)" "unprognostic (7.91e-2)" "unprognostic (2.82e-1)" "unprognostic (6.87e-2)" "unprognostic (2.59e-1)" 1.1 0.3 0.0 0.5 0.1 0.0 17.5 0.0 0.2 338.5 0.0 4.8 0.3 0.6 0.3 1015.0 0.4 1.8 1.7 0.1 0.0 0.8 0.4 2.0 0.1 0.1 0.1 0.3 0.8 1.0 2.0 2.4 0.2 1.3 10.6 0.0 145.0 0.5 1.8 318.2 0.6 0.4 0.0 0.3 5.0 1.6 0.1 9.1 2.2 1.1 292.9 0.7 582.6 0.3 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.2 1.8 0.0 0.0 14.7 0.0 1.3 0.0 0.0 0.0 0.0 22.7 0.0 0.0 0.3 0.0 0.0 3.9 0.0 0.0 0.0 0.2 0.0 0.9 19.3 0.0 2.1 0.0 0.0 2.6 2.0 0.3 0.0 0.0 0.0 0.0 5.7 2.8 0.0 0.6 0.0 0.0 6.6 4.6 0.0 0.0 0.0 0.1 0.0 0.0 5.0 2.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.3 5.7 9.6 45.4 0.3 0.2 53.7 1.5 331.1 102.4 0.0 4.2 3.4 1.2 34.3 115.6 0.0 0.0 1.9 0.0 177.9 0.0 0.2 11.0 2.5 0.7 12.9 4.2 0.0 0.7 1.3 2.1 2.6 17.9 4.8 1.3 0.0 7.9 0.2 0.1 0.0 0.8 33.8 16.2 0.8 2.1 3.8 0.6 0.7 3.6 2.8 0.0 0.0 0.0 2.0 1.2 7.6 60.3 0.0 3.7 0.7 0.0 0.0 9.4 0.0 0.0 0.2 2.4 1.3 4.6 1622.6 64.4 1.5 1.1 1.0 97.9 2.7 SPINK9 ENSG00000204909 "Serine peptidase inhibitor Kazal type 9" Q5DT21 5 148321203-148339852 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.0" "Group enriched" "Detected in some" 6 "Alveolar cells type 1: 16.0;Alveolar cells type 2: 27.9;Club cells: 14.9;granulocytes: 10.1;Respiratory ciliated cells: 14.6" "Cancer enhanced" "Detected in single" "endometrial cancer: 0.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 12.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 24.4;U-266/84: 26.9" "Low region specificity" "Detected in single" HPA038288 Uncertain Approved Nucleoplasm,Vesicles "Secreted in other tissues" NA NA 24000 "Cluster 42: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 16: U-266 - Nucleosome" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Vesicles" "HPA038288: AB_10795400" "unprognostic (1.84e-1)" "unprognostic (4.87e-3)" "unprognostic (2.88e-1)" "unprognostic (9.02e-2)" "unprognostic (5.49e-3)" "unprognostic (3.04e-2)" "unprognostic (3.04e-1)" "unprognostic (1.35e-1)" "unprognostic (1.51e-3)" "unprognostic (2.82e-2)" "unprognostic (1.91e-2)" "unprognostic (3.93e-1)" "unprognostic (2.01e-1)" "unprognostic (3.99e-2)" "unprognostic (1.90e-1)" 1.5 3.2 17.1 3.0 13.7 6.5 0.5 19.2 26.6 0.6 5.0 2.0 2.2 2.6 1.9 2.2 1.0 1.4 2.0 14.6 10.6 1.8 1.6 1.1 2.6 10.0 6.1 1.8 1.1 0.5 0.1 3.2 10.8 2.5 1.7 10.3 1.5 0.5 3.8 3.4 2.4 0.5 2.6 1.9 2.4 4.2 11.5 3.2 1.5 0.1 1.6 0.9 0.0 28.0 15.4 2.6 2.9 3.4 0.7 1.2 2.8 3.5 0.2 0.3 0.5 5.3 10.8 3.4 24.4 0.1 2.0 3.5 0.9 0.7 1.0 6.1 1.4 7.7 8.3 2.7 0.3 2.9 2.6 0.2 0.7 0.5 0.1 2.0 0.0 2.5 4.9 18.3 0.4 9.6 2.5 4.7 13.7 5.5 5.0 3.9 3.4 4.0 1.0 10.0 6.3 7.9 3.0 8.6 2.8 8.6 14.0 3.0 5.9 4.4 14.1 3.9 4.5 11.1 26.9 4.0 2.6 2.1 6.2 12.4 1.8 1.0 1.1 1.0 1.4 0.8 1.3 1.4 0.4 1.9 1.8 1.8 6.6 3.9 2.2 1.9 0.9 0.1 17.1 13.7 19.2 26.6 14.6 10.6 10.0 6.1 10.8 2.6 11.5 28.0 0.1 16.0 27.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.4 0.0 14.9 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.2 1.9 0.0 0.0 0.3 0.0 0.0 2.6 0.0 0.1 10.1 0.1 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.1 2.2 0.4 0.0 0.1 0.0 0.3 14.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.7 0.0 0.0 0.2 SPIRE2 "KIAA1832, spir-2" ENSG00000204991 "Spire type actin nucleation factor 2" Q8WWL2 16 89818179-89871319 "Predicted intracellular proteins" "Protein transport, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 21.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 54.9;Gastric mucus-secreting cells: 46.9;Intestinal goblet cells: 43.8;Paneth cells: 39.9;Syncytiotrophoblasts: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "OE19: 29.5;T-47d: 18.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041413, HPA049415" Uncertain Approved "Nucleoplasm,Vesicles,Intermediate filaments" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Nucleoplasm "Vesicles, Intermediate filaments" "HPA041413: AB_2677464, HPA049415: AB_2680755" "unprognostic (2.92e-1)" "unprognostic (1.39e-1)" "unprognostic (6.07e-3)" "unprognostic (6.96e-2)" "unprognostic (7.40e-2)" "unprognostic (7.31e-2)" "prognostic unfavorable (9.77e-5)" "unprognostic (2.10e-1)" "unprognostic (7.75e-2)" "unprognostic (5.34e-2)" "unprognostic (1.08e-2)" "unprognostic (6.95e-3)" "unprognostic (7.21e-3)" "unprognostic (6.65e-2)" "unprognostic (1.30e-1)" "unprognostic (3.27e-2)" "unprognostic (1.59e-2)" 1.6 2.1 8.8 1.2 9.0 1.2 1.9 12.5 12.3 2.5 3.8 15.7 7.8 1.7 1.8 2.9 6.1 2.0 0.9 9.1 7.6 4.5 6.5 2.3 0.5 9.8 7.9 1.8 2.2 3.6 21.5 4.5 10.4 4.7 8.2 3.1 2.5 3.1 0.6 2.0 9.2 1.0 5.5 1.0 14.4 5.0 7.5 0.4 6.9 0.0 0.4 6.1 2.2 8.5 0.4 8.4 5.2 4.2 1.4 0.9 17.5 2.7 1.6 3.9 1.6 3.2 9.0 5.8 1.2 0.8 4.0 9.0 2.2 0.3 1.1 2.2 10.1 1.3 7.1 8.9 1.4 0.3 1.8 1.8 2.0 1.2 1.0 0.5 0.2 0.5 9.2 1.4 1.1 12.8 0.1 2.2 5.7 29.5 5.3 4.6 1.9 1.3 2.0 8.6 13.6 7.0 11.6 5.0 5.1 4.4 18.8 3.0 0.4 2.3 4.9 3.3 2.5 0.7 3.7 0.5 3.5 2.1 4.9 2.4 0.5 0.3 0.4 0.3 0.2 0.4 0.3 0.2 0.1 0.7 0.4 0.4 2.0 0.5 0.5 0.6 0.2 0.3 8.8 9.0 12.5 12.3 9.1 7.6 9.8 7.9 10.4 5.5 7.5 8.5 0.7 6.4 4.8 10.7 0.6 0.9 5.1 1.7 2.2 13.0 4.3 2.8 2.4 14.3 2.4 12.9 4.2 15.7 2.1 54.9 3.9 1.5 3.1 11.9 2.6 1.1 15.7 0.0 20.2 0.4 3.6 1.4 46.9 3.2 0.0 4.2 0.0 2.4 2.7 23.5 23.6 43.8 2.0 1.0 1.1 2.5 0.9 1.4 0.0 1.9 0.2 2.8 1.0 7.1 4.1 1.5 39.9 1.9 0.7 5.0 29.8 0.8 13.5 10.7 0.0 2.8 1.6 6.0 8.8 3.8 0.6 70.5 1.3 5.7 33.5 30.2 SPNS1 "HSpin1, LAT, nrs, PP2030, SLC62A1, SPIN1, SPINL" ENSG00000169682 "Sphingolipid transporter 1 (putative)" Q9H2V7 16 28974221-28984548 "Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041995, HPA042988" Enhanced Approved "Nucleoli fibrillar center,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "Nucleoli fibrillar center, Golgi apparatus, Cytosol" "HPA041995: AB_10959609, HPA042988: AB_10964587" "unprognostic (3.54e-2)" "unprognostic (4.57e-4)" "unprognostic (2.15e-1)" "unprognostic (2.49e-1)" "unprognostic (2.08e-1)" "unprognostic (3.66e-1)" "unprognostic (7.86e-5)" "unprognostic (1.01e-1)" "unprognostic (2.00e-1)" "unprognostic (1.27e-1)" "unprognostic (4.12e-2)" "unprognostic (3.02e-3)" "unprognostic (8.85e-7)" "unprognostic (1.48e-1)" "unprognostic (6.15e-2)" "unprognostic (1.26e-3)" "unprognostic (1.12e-2)" 26.8 30.8 17.0 19.3 17.4 37.0 24.8 17.1 26.3 27.7 18.6 32.5 22.4 30.9 6.6 25.9 23.0 18.0 27.5 16.9 15.7 32.1 33.9 31.5 20.1 19.1 16.6 22.0 24.4 20.8 21.1 19.8 17.2 26.5 10.0 6.5 24.4 14.9 25.0 35.7 27.8 15.1 15.8 33.9 28.2 20.3 19.8 20.8 27.8 14.9 10.5 30.5 25.2 18.3 25.9 59.6 22.2 51.9 41.5 22.8 62.9 28.2 28.9 46.1 40.9 55.0 60.4 16.4 67.8 25.5 38.2 53.3 36.4 31.2 16.4 19.0 61.6 23.8 57.1 69.3 70.4 26.7 49.2 38.4 40.9 49.7 21.0 26.8 42.9 30.0 54.4 28.7 23.4 68.8 29.3 75.8 52.6 20.8 39.1 36.7 26.7 73.6 24.9 24.8 39.5 51.3 20.1 59.3 44.9 18.5 59.2 31.9 36.6 37.3 28.2 52.7 22.0 43.2 36.7 15.6 47.7 40.4 30.8 13.4 32.8 13.5 9.9 42.1 8.3 5.7 9.8 13.0 27.6 4.3 10.0 6.8 5.6 7.7 28.8 11.5 12.1 18.1 17.0 17.4 17.1 26.3 16.9 15.7 19.1 16.6 17.2 15.8 19.8 18.3 24.4 6.4 7.2 8.8 14.9 21.3 21.3 29.8 14.8 31.0 17.2 15.7 0.3 20.0 20.1 20.2 29.2 63.3 26.5 10.5 13.7 58.1 2.1 15.3 19.2 24.1 12.2 21.8 10.2 45.7 72.3 24.6 16.8 18.9 22.7 40.9 19.2 14.3 98.7 26.9 10.3 13.8 46.8 45.6 28.4 3.7 22.7 61.8 33.8 15.0 32.7 28.5 24.7 7.1 8.6 37.3 16.0 16.6 18.6 14.4 41.5 18.2 26.2 38.6 6.6 17.4 23.8 24.8 33.5 16.4 22.7 87.3 20.7 37.8 20.0 19.4 SPOCK1 "SPOCK, testican-1, TIC1" ENSG00000152377 "SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1" Q08629 5 136975298-137598379 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 172.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 252.8;Inhibitory neurons: 349.9;Muller glia cells: 243.8;Oligodendrocyte precursor cells: 273.4;Oligodendrocytes: 913.1;Peritubular cells: 150.1" "Cancer enriched" "Detected in all" 7 "prostate cancer: 83.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 573.1;hTERT-RPE1: 1112.8;HUVEC TERT2: 594.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007450, HPA026770" Uncertain Approved Vesicles "Secreted to blood" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA007450: AB_10603116, HPA026770: " "unprognostic (1.05e-1)" "unprognostic (9.25e-2)" "prognostic unfavorable (1.93e-4)" "unprognostic (1.58e-1)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.93e-5)" "unprognostic (5.83e-3)" "prognostic unfavorable (9.08e-4)" "unprognostic (1.00e-2)" "prognostic unfavorable (4.72e-4)" "unprognostic (9.09e-3)" "unprognostic (1.60e-1)" "prognostic unfavorable (3.77e-5)" "prognostic unfavorable (9.40e-4)" "unprognostic (1.26e-1)" "unprognostic (2.21e-1)" "unprognostic (1.90e-2)" 29.7 41.4 67.9 4.1 116.3 0.3 19.0 129.2 99.5 25.6 9.9 24.9 1.2 44.2 34.3 6.1 18.6 18.6 54.2 100.5 50.9 24.3 0.2 2.9 0.6 80.7 84.5 4.8 5.5 13.7 9.9 9.3 89.8 65.6 3.2 48.7 7.6 25.5 17.5 9.3 4.6 30.7 78.4 8.5 9.1 21.7 102.6 7.5 9.4 7.1 0.4 11.4 21.7 172.9 4.6 0.9 299.4 0.4 573.1 116.0 0.4 100.6 90.0 207.7 115.9 0.0 0.6 0.4 0.2 206.7 53.3 4.4 1.4 70.3 65.3 17.8 0.6 0.2 16.7 0.0 4.0 0.0 0.4 203.8 28.5 128.6 23.2 1112.8 594.4 0.2 0.0 0.4 60.5 0.5 0.0 0.2 19.1 0.0 28.4 0.0 0.2 0.0 140.3 9.4 3.7 14.4 49.9 0.8 0.1 35.6 0.4 1.2 98.9 294.0 10.6 102.1 28.5 0.1 0.1 0.1 159.4 4.4 136.9 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 67.9 116.3 129.2 99.5 100.5 50.9 80.7 84.5 89.8 78.4 102.6 172.9 2.0 0.0 0.0 91.7 0.0 1.8 1.6 5.8 0.0 9.7 0.4 0.4 58.8 1.5 0.4 22.0 2.1 0.4 0.0 0.2 1.9 0.6 12.0 4.2 37.9 8.4 35.0 0.0 252.8 1.4 0.3 58.8 0.0 2.9 0.0 0.1 1.1 0.0 0.9 8.4 349.9 0.1 16.2 1.2 3.0 9.5 17.4 1.6 7.2 17.8 2.3 243.8 0.0 273.4 913.1 2.0 0.1 150.1 0.1 40.9 0.0 3.1 0.9 7.3 13.1 11.6 16.4 7.4 7.1 0.7 1.4 0.1 0.4 0.0 0.3 3.2 SPON2 DIL1 ENSG00000159674 "Spondin 2" Q9BUD6 4 1166932-1208962 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 187.1" "Cell type enhanced" "Detected in many" "dendritic cells: 427.0;Endometrial stromal cells: 256.6;Extravillous trophoblasts: 355.8;Fibroblasts: 257.7;NK-cells: 1096.8" "Cancer enriched" "Detected in all" 7 "prostate cancer: 243.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "gdT-cell: 255.9" "Lineage enriched" "Detected in all" 5 "T-cells: 255.9" "Group enriched" "Detected in many" 5 "HHSteC: 303.8;HSkMC: 546.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA040170, HPA066095" Approved Approved Vesicles "Secreted to blood" NA NA 2600000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA040170: AB_2676868, HPA066095: AB_2685615" "unprognostic (1.22e-1)" "unprognostic (3.56e-1)" "unprognostic (3.07e-2)" "prognostic favorable (2.03e-4)" "unprognostic (7.64e-2)" "unprognostic (6.28e-2)" "unprognostic (2.70e-3)" "unprognostic (2.28e-3)" "unprognostic (2.76e-1)" "unprognostic (1.21e-1)" "unprognostic (1.82e-1)" "unprognostic (1.40e-1)" "unprognostic (1.23e-2)" "unprognostic (2.74e-3)" "unprognostic (1.22e-1)" "unprognostic (2.01e-2)" "prognostic unfavorable (9.22e-4)" 66.2 40.4 4.0 18.8 7.7 19.5 50.6 15.6 3.9 161.4 3.5 51.5 18.5 187.1 4.4 40.6 49.7 32.2 35.5 3.5 0.8 37.1 79.1 63.0 3.9 2.9 1.7 34.4 18.7 0.9 15.1 19.2 3.5 111.8 7.2 0.7 28.8 8.4 19.1 38.3 63.5 42.7 0.2 26.9 43.8 4.7 1.8 1.8 16.3 6.6 1.0 68.4 94.0 1.5 0.4 0.6 0.0 0.0 10.2 79.0 3.0 6.2 5.0 0.8 1.0 0.0 0.1 1.8 9.7 26.9 0.9 45.0 0.0 0.2 0.0 0.3 0.1 0.2 3.0 12.7 303.8 0.2 1.5 546.6 0.0 0.6 0.0 0.0 0.0 4.1 0.3 9.2 0.0 0.3 5.3 12.2 3.5 9.7 0.7 1.0 3.3 7.9 0.0 0.0 1.7 1.1 1.1 0.0 2.9 1.7 0.4 1.5 0.1 0.2 0.9 20.5 0.0 1.3 2.7 0.6 0.1 6.5 0.0 3.7 0.9 1.0 255.9 1.1 5.5 0.7 33.1 105.8 0.4 1.0 14.4 96.8 9.8 50.4 2.2 42.9 0.1 123.2 4.0 7.7 15.6 3.9 3.5 0.8 2.9 1.7 3.5 0.2 1.8 1.5 9.8 0.0 5.6 1.3 6.6 36.8 2.0 82.5 2.2 3.7 5.1 3.8 4.0 24.3 43.0 1.8 0.0 3.4 427.0 9.7 1.9 3.8 0.2 12.7 256.6 5.7 13.8 4.0 8.4 1.3 355.8 257.7 10.7 6.6 6.3 0.2 15.4 40.4 12.8 0.0 0.6 9.7 73.2 5.8 15.4 0.5 29.8 9.5 26.6 6.5 9.2 0.9 1096.8 0.5 0.7 1.5 6.7 9.4 64.0 15.8 16.3 28.3 32.6 0.4 6.6 22.5 89.9 0.2 0.5 21.3 21.5 38.9 100.8 8.1 7.9 13.2 SPOPL BTBD33 ENSG00000144228 "Speckle type BTB/POZ protein like" Q6IQ16 2 138501770-138573547 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 5.7" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034687 Uncertain Approved Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA034687: AB_10670573" "unprognostic (1.39e-3)" "unprognostic (1.24e-1)" "unprognostic (2.48e-2)" "unprognostic (3.02e-2)" "unprognostic (3.37e-1)" "unprognostic (3.12e-2)" "unprognostic (4.42e-2)" "unprognostic (2.41e-1)" "unprognostic (1.40e-1)" "unprognostic (2.04e-1)" "unprognostic (2.75e-2)" "unprognostic (8.90e-2)" "prognostic favorable (3.63e-4)" "unprognostic (2.25e-2)" "unprognostic (1.15e-1)" "unprognostic (9.09e-2)" "unprognostic (1.91e-3)" 7.9 5.9 6.1 9.7 8.1 14.2 12.7 6.7 8.0 6.6 4.8 8.3 7.9 8.5 3.6 6.2 6.6 7.3 5.4 5.5 6.2 8.8 9.4 7.6 11.3 7.6 9.1 10.3 5.6 7.3 4.3 6.8 7.9 9.4 8.9 9.8 11.5 8.1 4.6 8.5 8.4 7.4 7.6 11.2 9.3 3.7 7.1 4.9 8.5 8.0 9.7 8.0 6.3 9.1 13.3 4.0 7.2 7.0 5.8 9.7 13.8 9.6 7.2 5.9 7.0 14.8 10.6 14.2 9.0 8.3 5.3 5.1 9.5 8.4 12.4 11.1 7.7 9.0 9.2 23.2 6.0 10.0 12.1 6.4 12.3 11.7 10.8 12.0 9.6 3.3 3.0 19.2 10.1 12.9 1.0 9.4 6.5 9.3 6.9 5.0 12.6 8.1 9.3 18.7 8.4 10.3 14.7 13.8 7.3 8.5 7.6 10.9 9.6 9.5 8.1 12.0 14.7 27.6 21.6 10.3 15.9 9.2 8.8 0.4 1.6 2.8 0.3 1.5 0.3 1.1 0.2 0.3 2.2 1.1 0.1 0.2 5.7 0.4 1.3 0.9 0.4 0.6 6.1 8.1 6.7 8.0 5.5 6.2 7.6 9.1 7.9 7.6 7.1 9.1 16.9 12.8 13.6 25.8 25.9 55.6 11.4 7.9 13.6 9.9 38.8 13.8 13.2 15.7 20.6 3.7 4.2 6.4 15.0 20.3 7.9 10.1 1.7 11.9 10.3 12.4 19.2 5.0 55.3 13.3 7.3 12.3 17.3 11.8 8.8 12.5 8.9 13.8 8.9 18.5 67.2 19.8 18.3 31.5 37.7 2.8 17.1 33.2 12.4 48.7 27.5 9.2 9.2 63.8 54.1 21.1 12.6 15.8 11.8 19.5 11.0 16.4 16.1 16.6 6.6 18.8 18.5 10.0 18.8 10.3 44.8 6.2 10.8 4.9 12.0 21.3 SPPL2A "IMP3, PSL2" ENSG00000138600 "Signal peptide peptidase like 2A" Q8TCT8 15 50702266-50765709 "Enzymes, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036062, HPA067304" Enhanced Supported Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA036062: AB_10611670, HPA067304: AB_2685820" "unprognostic (1.66e-1)" "unprognostic (1.03e-1)" "unprognostic (2.70e-1)" "unprognostic (5.82e-3)" "unprognostic (3.71e-1)" "unprognostic (1.70e-1)" "unprognostic (2.15e-1)" "unprognostic (1.88e-1)" "unprognostic (2.22e-2)" "unprognostic (6.36e-2)" "unprognostic (2.04e-2)" "unprognostic (4.00e-2)" "unprognostic (3.11e-2)" "unprognostic (2.26e-2)" "unprognostic (1.44e-2)" "unprognostic (6.96e-2)" "unprognostic (3.66e-1)" 41.1 34.7 8.3 57.6 10.9 54.5 32.0 11.1 8.5 36.6 48.6 93.4 79.6 27.9 21.5 26.5 26.8 39.4 37.1 6.8 12.3 57.9 107.0 43.4 40.2 15.3 12.8 13.6 63.7 158.5 13.0 54.1 12.5 29.5 82.8 12.5 44.5 32.6 109.3 25.2 67.6 41.0 11.2 37.3 41.7 18.5 12.1 39.5 35.2 81.8 41.7 51.7 20.9 14.5 57.3 96.9 37.0 49.2 142.3 84.3 58.2 89.1 149.1 80.5 114.1 113.1 64.3 35.1 65.0 176.3 120.7 83.5 45.2 54.3 89.5 72.2 27.5 67.0 61.5 58.9 117.4 42.0 104.5 73.9 98.3 66.8 106.7 59.4 80.2 37.7 51.3 134.2 107.6 131.5 20.1 16.2 15.8 90.8 22.0 24.2 57.3 77.6 109.7 130.4 29.7 33.4 54.0 102.7 63.4 74.0 73.2 81.6 98.9 128.7 51.7 83.7 106.7 54.0 100.2 38.8 58.1 69.4 90.3 48.7 52.3 48.9 27.9 48.6 17.4 18.3 22.3 25.5 37.4 19.2 12.4 20.5 37.7 23.5 56.6 33.1 30.4 50.2 8.3 10.9 11.1 8.5 6.8 12.3 15.3 12.8 12.5 11.2 12.1 14.5 66.2 48.1 35.9 20.5 51.9 43.1 79.1 76.3 37.5 14.8 36.4 21.3 77.5 52.9 44.3 68.0 20.9 136.5 72.7 215.5 23.5 87.1 18.8 107.2 56.6 59.6 38.4 30.3 32.0 167.1 88.3 74.3 52.0 57.3 45.7 20.5 46.8 124.1 85.9 8.4 31.4 86.5 36.7 68.7 55.7 7.0 44.7 83.0 32.0 23.4 134.5 27.5 64.9 25.6 26.2 131.9 127.3 36.5 49.9 92.2 143.0 46.8 41.8 17.2 26.3 88.0 51.6 31.7 15.3 39.3 38.8 204.5 60.6 30.8 76.0 94.1 SPPL3 "DKFZP586C1324, IMP2, MGC126674, MGC126676, MGC90402, PSL4" ENSG00000157837 "Signal peptide peptidase like 3" Q8TCT6 12 120762510-120904358 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 192.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004194, HPA059958" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Plasma membrane" "HPA004194: AB_2667171, HPA059958: AB_2684179" "unprognostic (3.29e-1)" "unprognostic (2.29e-2)" "unprognostic (3.39e-2)" "unprognostic (1.63e-1)" "unprognostic (2.06e-1)" "unprognostic (7.96e-3)" "prognostic unfavorable (1.29e-5)" "unprognostic (3.17e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (2.48e-1)" "unprognostic (2.44e-1)" "unprognostic (2.66e-1)" "unprognostic (9.34e-2)" "unprognostic (9.92e-2)" "unprognostic (7.54e-2)" "unprognostic (9.40e-2)" 20.9 14.9 25.3 11.9 28.1 20.9 24.2 29.0 27.5 30.0 13.1 26.7 18.2 26.3 15.7 44.3 28.6 18.7 18.1 25.4 30.6 22.8 19.3 20.4 15.9 25.0 26.0 31.4 21.3 49.6 13.9 28.4 26.1 20.6 27.2 15.5 20.2 27.0 15.7 56.5 18.8 29.6 24.1 24.3 15.2 39.0 26.4 32.7 31.2 19.6 27.8 28.6 34.2 31.4 30.0 29.2 43.4 27.4 56.2 37.7 30.5 22.5 66.6 47.4 37.9 30.5 29.9 27.4 0.1 39.4 42.0 35.6 44.8 48.4 48.9 21.9 27.5 23.6 16.2 23.4 59.2 27.4 29.3 38.1 75.9 40.7 38.1 56.0 47.1 41.5 26.5 13.4 41.2 26.3 36.7 22.0 29.2 27.8 20.6 21.6 36.6 19.7 36.8 83.8 29.7 31.9 42.8 19.6 34.7 46.1 58.9 18.7 35.4 21.9 29.5 13.6 17.1 30.9 60.3 26.4 32.5 22.3 36.9 4.8 1.2 1.1 1.3 1.2 1.8 1.3 1.6 1.7 2.1 1.6 1.5 1.7 2.2 1.3 1.1 2.7 1.4 0.7 25.3 28.1 29.0 27.5 25.4 30.6 25.0 26.0 26.1 24.1 26.4 31.4 35.2 19.2 20.8 79.3 25.3 55.1 32.3 29.4 43.3 37.8 35.2 24.1 21.2 20.0 19.8 40.5 27.1 42.0 21.2 47.2 1.9 19.3 8.6 20.9 26.9 33.0 27.1 14.5 97.2 24.7 29.0 33.2 25.0 29.7 4.5 68.7 37.5 33.1 38.3 37.0 112.6 33.7 22.4 38.1 39.3 8.0 28.6 34.5 26.6 79.6 26.6 23.0 16.5 141.3 192.3 22.8 34.9 35.0 22.0 33.4 34.0 18.1 18.1 22.4 13.1 32.3 27.4 55.6 41.1 76.9 84.7 64.6 22.4 35.0 35.4 37.6 SPRYD3 FLJ14800 ENSG00000167778 "SPRY domain containing 3" Q8NCJ5 12 53064316-53079404 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039426, HPA039685" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "Vesicles, Plasma membrane, Actin filaments" "HPA039426: AB_10673358, HPA039685: AB_2676623" "unprognostic (7.73e-3)" "unprognostic (6.55e-2)" "unprognostic (1.37e-2)" "unprognostic (5.05e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (9.46e-4)" "unprognostic (1.27e-3)" "unprognostic (2.58e-1)" "unprognostic (1.83e-2)" "unprognostic (1.43e-2)" "unprognostic (2.64e-2)" "unprognostic (3.14e-2)" "prognostic favorable (1.78e-15)" "unprognostic (9.82e-2)" "unprognostic (5.27e-2)" "unprognostic (7.44e-3)" "unprognostic (1.41e-1)" 32.2 29.2 70.6 18.4 77.9 6.4 30.2 35.6 84.2 33.6 38.1 32.8 18.9 38.1 36.2 31.7 45.1 20.4 42.4 79.9 60.4 29.5 22.1 23.6 17.4 61.7 55.1 43.5 50.0 43.3 60.7 14.0 61.5 34.5 17.0 39.3 43.9 40.6 21.2 27.0 23.4 31.6 43.8 24.3 35.8 11.5 58.0 13.7 34.6 23.1 20.6 36.5 30.7 67.9 28.4 43.0 5.6 11.5 45.4 22.4 7.3 42.6 22.2 16.1 10.1 7.4 23.8 18.6 34.2 53.5 19.2 26.0 7.6 32.9 10.5 19.4 11.3 11.5 25.5 16.9 34.0 22.3 20.1 20.2 51.6 23.1 34.9 31.6 33.5 9.3 10.4 45.3 28.5 62.3 16.3 11.7 3.2 23.1 30.8 7.1 9.5 38.4 20.6 22.3 9.4 8.9 37.3 34.6 18.1 3.0 31.8 16.7 46.4 18.1 17.9 40.9 29.0 24.7 24.1 5.4 53.8 19.5 22.4 29.9 16.7 47.5 32.7 28.9 30.9 14.6 22.4 26.9 15.5 11.3 18.8 22.7 25.8 17.0 32.8 7.4 13.5 28.9 70.6 77.9 35.6 84.2 79.9 60.4 61.7 55.1 61.5 43.8 58.0 67.9 13.4 3.2 10.1 4.9 13.3 5.7 19.5 12.0 13.1 46.4 11.3 8.8 20.4 17.2 10.4 18.4 8.4 6.2 8.8 9.1 11.7 30.4 0.9 21.2 10.9 17.1 11.5 2.1 14.4 36.5 14.6 22.9 15.8 16.1 10.1 5.1 18.9 9.1 11.8 43.7 13.5 13.8 10.2 11.7 5.7 2.7 16.1 10.3 10.6 3.7 15.0 38.5 16.5 4.5 5.6 28.6 9.3 33.1 19.1 20.8 10.7 15.6 18.2 23.8 19.7 11.1 20.0 4.5 3.9 12.0 9.5 4.2 14.9 5.1 7.9 16.4 SPRYD7 "C13orf1, CLLD6" ENSG00000123178 "SPRY domain containing 7" Q5W111 13 49912702-49936490 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 131.4;Spermatocytes: 167.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043934 Approved Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 54: Non-specific - Microtubule organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA043934: AB_10960545" "unprognostic (1.83e-2)" "prognostic unfavorable (8.48e-6)" "unprognostic (2.57e-1)" "unprognostic (4.95e-2)" "unprognostic (4.45e-1)" "unprognostic (1.87e-3)" "unprognostic (3.54e-2)" "unprognostic (1.12e-1)" "unprognostic (4.05e-1)" "unprognostic (3.12e-3)" "unprognostic (3.34e-3)" "unprognostic (1.17e-1)" "unprognostic (1.01e-1)" "unprognostic (6.53e-2)" "unprognostic (1.51e-1)" "unprognostic (1.65e-2)" "unprognostic (1.06e-2)" 5.3 8.6 9.4 3.8 9.9 3.2 5.6 7.9 14.6 4.9 4.8 7.6 6.3 4.3 5.3 7.7 4.7 3.1 11.6 10.3 10.4 8.4 10.7 10.2 3.2 8.6 9.0 5.4 5.5 9.5 6.0 6.2 9.8 6.4 6.6 12.3 4.7 4.9 23.9 6.0 7.2 5.2 7.9 4.0 7.0 8.9 10.0 2.6 6.7 15.4 3.6 5.7 5.4 9.1 10.1 8.5 5.4 6.0 6.5 9.2 12.3 19.5 9.1 13.5 7.7 15.5 8.1 9.8 6.1 14.4 11.1 8.5 12.1 18.1 18.7 16.3 10.9 10.5 6.5 10.9 22.1 25.4 7.2 8.0 20.0 11.8 23.0 8.4 8.4 5.5 12.0 8.6 31.6 6.2 0.9 11.9 2.1 15.3 9.6 4.7 9.1 6.0 14.1 7.6 4.5 5.6 5.7 12.8 9.8 6.8 11.9 15.7 10.8 12.2 6.8 11.3 19.8 5.3 8.8 7.5 9.5 10.2 14.0 0.7 2.0 1.7 2.0 2.3 4.1 5.3 1.9 2.6 2.5 4.3 1.5 2.3 0.4 6.8 4.6 1.7 3.1 1.8 9.4 9.9 7.9 14.6 10.3 10.4 8.6 9.0 9.8 7.9 10.0 9.1 23.7 131.4 32.8 22.2 17.0 20.3 23.3 64.1 21.1 29.4 17.2 20.1 60.1 21.5 32.1 12.9 8.4 38.8 11.2 42.4 52.8 32.1 118.5 25.9 20.0 21.5 23.4 6.5 35.5 25.8 45.0 21.4 15.3 13.3 17.7 12.5 19.2 52.1 27.9 23.5 33.3 21.4 26.4 7.6 13.9 24.3 21.1 14.1 23.2 24.4 14.6 21.6 12.3 24.6 60.1 37.2 23.6 20.3 12.4 23.9 34.5 82.1 26.6 30.7 6.6 20.1 29.8 167.1 56.9 33.8 31.0 39.8 11.9 27.7 22.2 10.4 SPTAN1 ENSG00000197694 "Spectrin alpha, non-erythrocytic 1" Q13813 9 128552558-128633662 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin capping, Actin-binding, Calmodulin-binding" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Bipolar cells: 296.6;Cone photoreceptor cells: 310.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004581, HPA007927" Enhanced Approved Vesicles,Microtubules NA NA 1600000 "Cluster 13: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "Vesicles, Microtubules" "CAB004581: AB_671135, HPA007927: AB_1857435" "unprognostic (1.46e-2)" "unprognostic (2.73e-2)" "unprognostic (1.56e-1)" "unprognostic (9.06e-2)" "unprognostic (3.24e-1)" "unprognostic (4.02e-2)" "unprognostic (2.56e-3)" "unprognostic (2.20e-1)" "unprognostic (1.81e-1)" "unprognostic (1.30e-2)" "unprognostic (2.49e-1)" "unprognostic (1.36e-1)" "prognostic favorable (1.84e-12)" "unprognostic (2.94e-2)" "unprognostic (1.60e-1)" "unprognostic (4.18e-3)" "unprognostic (2.19e-3)" 48.8 31.4 81.7 38.6 85.0 28.1 36.6 54.4 99.7 39.4 0.4 47.3 24.7 57.1 32.9 36.8 54.0 32.5 65.7 90.9 43.5 34.6 22.8 55.1 38.5 142.7 49.6 51.6 24.0 47.1 32.5 57.1 155.0 32.7 36.3 103.1 31.9 46.5 23.9 69.4 34.9 58.8 65.6 44.3 31.1 44.9 61.5 45.4 38.4 22.3 38.0 40.0 36.4 55.3 108.1 116.9 75.2 83.4 107.6 121.0 61.5 90.2 75.2 99.4 74.1 167.3 74.6 94.3 78.3 137.0 69.8 193.3 80.7 90.4 61.1 53.2 47.9 15.9 324.4 94.4 61.3 70.9 51.0 58.3 71.6 166.3 55.8 83.9 134.4 87.2 9.1 107.6 98.6 74.6 136.3 29.5 96.1 125.9 72.1 91.0 90.2 59.7 80.2 91.1 58.1 91.1 296.1 40.3 42.9 91.8 70.0 19.8 232.5 68.5 102.2 100.0 71.2 65.3 82.6 51.8 83.5 31.5 65.9 3.3 1.6 3.9 9.7 1.3 13.5 6.3 12.4 9.2 2.4 5.8 7.6 7.9 1.5 7.1 1.2 3.0 15.3 5.8 81.7 85.0 54.4 99.7 90.9 43.5 142.7 49.6 155.0 65.6 61.5 55.3 144.9 70.5 27.5 123.7 56.3 37.3 27.8 34.3 25.6 296.6 69.8 83.2 68.5 68.6 33.9 101.2 310.6 27.5 112.6 145.4 7.9 67.6 18.0 108.2 71.4 103.8 56.9 13.7 159.5 59.2 16.0 77.8 76.5 87.5 12.0 47.9 96.8 36.2 29.2 124.5 183.8 54.1 30.5 22.2 29.4 40.5 85.1 32.8 35.6 74.9 24.4 97.7 48.4 87.4 17.4 102.2 93.0 94.8 70.5 45.9 62.4 22.8 71.3 156.5 26.3 53.0 60.0 33.0 44.5 43.7 45.5 18.2 95.4 22.0 73.6 65.7 SPTBN2 SCA5 ENSG00000173898 "Spectrin beta, non-erythrocytic 2" O15020 11 66682497-66729226 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.6;skin 1: 85.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 86.5;Cone photoreceptor cells: 104.3;Early spermatids: 30.9;Late spermatids: 77.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 45.6;NTERA-2: 49.1;SCLC-21H: 49.9;SK-BR-3: 52.3;T-47d: 67.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009844, HPA039293, HPA043529" Enhanced Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" Vesicles "CAB009844: AB_2194521, HPA039293: AB_2676430, HPA043529: AB_2678531" "unprognostic (9.34e-2)" "unprognostic (5.71e-2)" "unprognostic (4.89e-2)" "unprognostic (3.41e-3)" "unprognostic (4.91e-1)" "unprognostic (6.05e-3)" "unprognostic (4.45e-2)" "unprognostic (1.38e-2)" "unprognostic (7.25e-2)" "unprognostic (1.67e-2)" "prognostic unfavorable (3.14e-5)" "unprognostic (1.64e-1)" "unprognostic (1.05e-3)" "unprognostic (1.34e-1)" "unprognostic (1.84e-1)" "unprognostic (3.99e-2)" "unprognostic (1.00e-3)" 1.3 14.4 26.8 1.0 32.6 2.3 7.7 29.7 73.6 14.3 0.0 0.9 0.9 1.7 1.2 39.8 3.7 1.7 1.4 38.8 0.3 37.5 23.3 1.1 0.2 4.8 0.9 0.9 16.7 13.1 16.4 0.4 3.2 12.4 0.7 14.7 29.6 4.7 0.5 85.5 1.0 1.1 0.0 0.9 2.9 52.8 4.6 1.0 0.3 0.1 6.7 1.6 16.5 24.2 20.5 7.4 3.4 0.3 0.1 0.0 0.6 0.3 0.1 0.1 0.0 4.8 28.2 0.2 3.7 0.0 0.7 16.9 25.2 2.4 0.0 0.1 10.4 0.1 45.6 3.0 0.8 7.3 0.6 0.2 11.5 0.0 7.4 4.2 6.3 5.2 7.3 0.1 0.1 35.2 6.3 3.5 49.1 28.7 21.1 23.8 2.8 14.7 9.6 4.8 49.9 29.4 14.0 52.3 3.2 2.7 67.2 2.4 1.4 0.1 8.6 1.3 11.5 0.7 3.0 14.7 0.1 0.1 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 26.8 32.6 29.7 73.6 38.8 0.3 4.8 0.9 3.2 0.0 4.6 24.2 0.7 3.2 1.1 4.9 0.3 3.7 2.7 3.2 2.8 11.0 4.7 4.6 1.8 1.5 4.6 86.5 104.3 0.9 0.0 0.6 0.0 2.6 30.9 3.6 1.8 1.1 3.0 7.2 29.3 10.0 0.3 0.8 1.5 3.6 0.0 1.4 1.4 24.7 0.1 0.0 20.7 1.6 0.0 0.3 0.7 77.6 1.8 0.1 0.0 2.8 0.6 1.6 0.0 7.5 4.6 7.5 0.2 1.5 0.8 3.2 0.2 1.3 3.5 21.3 0.0 0.2 0.5 8.5 9.4 14.6 12.5 0.3 0.2 0.1 0.8 1.7 SQLE ENSG00000104549 "Squalene epoxidase" Q14534 8 124998497-125022283 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018038, HPA020762" Enhanced Uncertain Vesicles,Cytosol NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 37: Intestine - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Cytosol" "HPA018038: AB_2669753, HPA020762: AB_2670512" "unprognostic (1.37e-2)" "unprognostic (6.26e-3)" "unprognostic (5.12e-2)" "unprognostic (9.51e-3)" "unprognostic (4.63e-1)" "prognostic unfavorable (7.42e-4)" "unprognostic (4.76e-3)" "prognostic unfavorable (4.67e-4)" "unprognostic (3.45e-2)" "unprognostic (7.21e-2)" "prognostic unfavorable (2.73e-4)" "unprognostic (7.51e-2)" "prognostic unfavorable (5.70e-4)" "unprognostic (9.71e-2)" "unprognostic (4.62e-2)" "unprognostic (1.19e-3)" "unprognostic (7.74e-3)" 8.6 31.1 17.5 19.6 27.0 23.0 22.1 26.8 24.0 30.7 25.4 21.6 31.0 16.4 9.1 78.7 18.6 10.7 7.2 18.6 24.4 17.1 72.3 30.9 17.7 47.3 27.7 14.3 10.7 22.7 16.5 47.5 35.1 25.0 18.6 17.8 19.1 7.6 1.4 49.4 14.0 12.3 27.6 9.7 21.8 59.4 21.8 14.2 10.5 1.6 29.4 14.7 46.2 34.6 135.5 51.5 301.6 87.2 91.7 154.1 30.5 34.9 106.3 46.5 84.7 70.6 192.3 92.7 49.2 43.2 186.0 101.0 127.3 192.4 53.6 77.1 268.3 265.2 32.6 181.1 134.6 31.5 74.6 106.1 201.4 138.8 113.3 29.8 51.5 64.2 153.8 174.8 38.1 223.7 109.6 39.3 125.2 92.6 35.2 47.5 55.4 126.6 329.3 153.3 93.9 47.6 71.6 226.3 74.1 96.5 60.7 81.3 50.8 19.2 66.0 22.9 31.6 31.6 69.6 126.6 32.0 93.7 33.8 1.5 6.3 0.7 10.6 10.8 5.0 16.6 6.0 9.5 15.2 17.1 8.2 8.6 0.2 12.6 12.7 10.8 7.1 7.7 17.5 27.0 26.8 24.0 18.6 24.4 47.3 27.7 35.1 27.6 21.8 34.6 13.2 60.9 97.9 21.5 34.7 22.9 64.0 199.9 16.5 41.8 35.6 27.3 6.1 31.5 129.6 53.3 50.1 99.7 20.6 81.6 7.9 60.3 21.0 95.9 23.3 39.7 31.7 22.3 14.3 83.6 133.7 35.3 51.0 80.5 41.3 77.1 9.7 127.9 61.1 148.0 18.8 58.0 126.1 10.9 30.1 13.2 23.9 22.2 21.4 13.1 91.0 24.3 8.2 20.1 77.9 98.6 38.4 10.9 30.6 118.0 17.3 3.7 123.0 61.1 26.3 12.5 42.0 179.5 128.6 69.5 89.1 217.1 21.1 171.8 35.0 114.8 SQSTM1 "A170, OSIL, p60, p62, p62B, PDB3" ENSG00000161011 "Sequestosome 1" Q13501 5 179806398-179838078 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Autophagy, Differentiation, Immunity" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1183.4" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 2045.0;Urothelial cells: 2233.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 1923.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004587, HPA064165, HPA068843" Supported Enhanced Vesicles,Cytosol No No 81000 "Cluster 38: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 44: HDLM-2 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Cytosol" "CAB004587: AB_628279, HPA064165: AB_2685203, HPA068843: AB_2732120" "unprognostic (1.08e-1)" "unprognostic (1.39e-1)" "unprognostic (3.19e-1)" "unprognostic (9.45e-2)" "unprognostic (1.47e-2)" "unprognostic (1.08e-1)" "prognostic unfavorable (2.31e-5)" "unprognostic (1.34e-1)" "unprognostic (2.34e-1)" "unprognostic (5.65e-2)" "unprognostic (1.66e-1)" "unprognostic (1.70e-1)" "unprognostic (9.52e-2)" "unprognostic (3.21e-1)" "unprognostic (8.68e-3)" "unprognostic (4.41e-2)" "unprognostic (2.01e-1)" 335.0 472.6 171.4 86.0 208.8 135.8 269.5 199.6 207.2 242.8 218.9 262.0 112.1 278.8 91.7 192.3 207.5 188.2 310.1 163.8 200.6 221.5 392.0 263.4 81.4 203.9 183.3 235.6 231.3 121.4 181.5 118.7 190.5 206.2 82.3 46.4 289.7 174.2 1183.4 194.7 187.4 132.7 179.5 179.0 263.6 65.7 205.7 89.4 316.4 287.2 96.4 347.3 211.0 236.5 130.1 740.6 36.9 114.3 547.8 384.8 546.3 187.9 596.3 164.1 201.2 154.6 532.9 16.0 522.7 298.9 898.3 170.8 79.9 181.9 76.9 1923.9 97.6 58.5 303.9 223.4 1167.2 59.9 365.0 337.1 181.2 273.0 441.5 390.8 152.6 17.3 68.0 472.1 327.0 111.6 26.4 62.0 93.8 410.0 195.1 54.8 78.8 213.7 243.6 609.6 79.0 74.5 253.2 274.3 662.2 62.3 143.8 120.4 286.2 243.1 103.4 252.3 271.6 723.7 819.3 73.5 521.1 111.6 338.4 807.6 412.3 422.2 194.7 268.3 231.3 156.5 170.1 174.6 227.5 168.2 131.8 139.1 672.6 196.3 260.3 89.6 262.1 439.8 171.4 208.8 199.6 207.2 163.8 200.6 203.9 183.3 190.5 179.5 205.7 236.5 411.1 185.9 248.8 36.9 280.0 297.5 1289.0 320.4 799.6 81.7 280.7 253.0 38.5 314.5 247.8 121.4 54.2 266.8 276.4 572.9 234.8 906.0 34.2 408.7 255.4 415.8 340.4 89.0 35.2 686.7 133.2 516.0 1270.6 589.7 386.3 73.8 142.5 297.8 288.3 90.9 37.2 337.2 236.0 149.8 556.3 72.2 325.3 388.3 231.3 28.1 611.3 143.3 125.7 16.6 62.2 639.4 618.9 259.2 606.5 1281.6 311.3 327.1 190.1 73.5 164.3 356.4 316.1 45.5 48.0 595.4 259.1 2045.0 259.9 133.4 242.3 2233.9 SREBF2 "bHLHd2, SREBP2" ENSG00000198911 "Sterol regulatory element binding transcription factor 2" Q12772 22 41833079-41907307 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031962, HPA031963" Approved Supported "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 27: Brain & Skin - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Vesicles" "Endoplasmic reticulum" "HPA031962: AB_10601266, HPA031963: AB_2674090" "unprognostic (6.53e-2)" "unprognostic (6.07e-2)" "unprognostic (1.75e-2)" "unprognostic (1.50e-3)" "unprognostic (3.41e-3)" "unprognostic (9.08e-2)" "unprognostic (5.04e-2)" "unprognostic (1.31e-1)" "unprognostic (4.78e-1)" "unprognostic (1.04e-2)" "unprognostic (2.30e-1)" "unprognostic (9.85e-2)" "prognostic favorable (1.37e-4)" "unprognostic (4.68e-2)" "unprognostic (1.92e-2)" "unprognostic (3.22e-1)" "unprognostic (7.93e-3)" 22.8 80.7 50.1 31.1 58.7 32.3 24.5 22.3 60.5 26.5 2.5 47.1 40.8 34.4 60.5 82.0 27.4 25.3 53.8 51.8 32.3 33.3 36.2 43.2 35.2 38.5 37.8 35.8 45.8 51.4 30.5 24.5 38.3 33.5 31.6 21.0 49.1 22.9 34.1 58.4 35.9 30.1 16.1 26.1 53.8 20.4 37.8 25.0 23.3 33.5 36.2 29.7 39.0 45.1 65.5 45.8 119.4 111.6 68.4 90.9 66.7 21.4 71.1 24.8 50.5 54.3 84.2 115.8 29.7 52.6 91.1 109.6 68.7 141.8 17.5 32.9 75.0 58.0 79.7 54.6 113.8 85.7 37.9 85.8 78.7 65.1 80.6 56.7 49.2 64.2 60.6 135.9 26.4 83.1 62.5 64.5 75.7 81.2 34.9 71.3 68.1 189.0 103.3 67.6 48.2 36.3 49.1 89.3 91.7 69.5 56.3 150.2 53.0 33.2 61.0 15.9 25.8 98.3 54.3 91.7 32.4 64.0 51.9 0.0 4.7 1.6 4.6 3.6 3.1 7.0 2.5 3.3 5.0 4.8 2.2 2.6 0.7 1.4 3.1 6.3 1.5 4.8 50.1 58.7 22.3 60.5 51.8 32.3 38.5 37.8 38.3 16.1 37.8 45.1 14.5 44.8 43.3 100.6 35.4 16.3 13.5 52.2 30.7 41.0 36.3 23.1 30.3 37.1 38.0 58.8 10.4 25.4 23.5 67.0 3.9 20.3 15.9 25.2 10.5 16.8 49.1 14.1 72.6 44.3 22.6 16.3 42.8 59.2 12.7 43.2 8.2 34.3 14.8 57.2 75.1 39.4 52.9 10.3 14.8 7.0 31.4 16.3 7.2 67.5 18.1 18.6 20.6 90.5 129.5 38.4 30.5 27.4 29.2 27.9 26.3 4.8 30.0 18.7 19.7 13.7 20.5 8.4 13.8 55.7 28.1 36.5 19.0 43.0 40.3 30.2 SRR "ILV1, ISO1" ENSG00000167720 "Serine racemase" Q9GZT4 17 2303383-2325260 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Isomerase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 23.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007529, CAB015343" Approved Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Vesicles "CAB015343: AB_2195009, HPA007529: AB_2667853" "unprognostic (2.96e-1)" "unprognostic (7.86e-2)" "unprognostic (6.01e-2)" "prognostic favorable (6.20e-5)" "unprognostic (3.05e-1)" "unprognostic (1.57e-2)" "unprognostic (4.32e-2)" "unprognostic (9.97e-2)" "unprognostic (9.09e-2)" "unprognostic (4.85e-2)" "prognostic favorable (8.16e-4)" "unprognostic (5.17e-2)" "prognostic favorable (2.45e-6)" "unprognostic (6.14e-2)" "unprognostic (1.99e-1)" "unprognostic (1.89e-1)" "unprognostic (5.84e-2)" 10.5 7.8 11.0 6.6 11.5 13.9 8.9 12.5 13.1 6.8 13.0 9.4 6.9 7.5 10.3 10.9 8.7 8.3 10.9 9.4 13.4 9.0 8.2 6.1 6.6 11.2 12.4 8.4 11.9 12.3 4.9 5.4 12.7 8.4 7.5 16.6 10.7 7.7 15.6 11.8 5.9 7.0 11.1 6.9 8.0 7.1 12.5 9.0 11.8 6.7 5.4 8.4 5.3 11.8 14.8 27.0 42.7 17.9 24.9 24.4 22.8 29.8 20.2 19.4 20.5 25.3 18.1 27.5 4.1 29.1 14.3 30.2 12.2 11.4 24.6 32.6 26.0 14.6 20.3 9.6 22.5 4.3 8.0 22.9 11.5 41.4 21.0 21.2 28.6 28.2 15.2 19.8 43.9 8.4 28.7 5.8 10.0 13.8 19.9 45.5 48.8 13.3 22.9 6.9 9.2 23.4 26.8 3.3 14.3 14.6 20.7 10.3 21.3 21.4 14.7 24.7 19.0 16.7 26.0 5.1 36.9 13.7 29.8 4.3 8.1 5.6 8.8 8.4 9.1 10.1 11.2 9.1 15.6 10.2 9.2 12.1 1.0 15.7 14.0 11.0 8.8 8.5 11.0 11.5 12.5 13.1 9.4 13.4 11.2 12.4 12.7 11.1 12.5 11.8 5.0 3.2 3.7 3.6 2.1 2.9 3.5 17.4 1.8 8.5 5.5 4.6 4.2 1.5 8.4 1.8 0.0 5.9 3.4 3.0 13.7 9.6 1.9 6.6 5.5 5.4 1.8 5.2 3.5 6.6 3.2 5.7 3.6 4.6 0.0 13.2 8.2 3.2 9.3 16.8 4.9 2.5 12.2 4.6 4.9 1.5 4.1 3.7 5.4 4.7 9.3 11.0 5.2 5.0 7.8 6.7 0.8 5.3 6.1 2.9 2.9 6.3 10.2 5.6 0.0 4.6 6.5 23.3 13.1 4.7 2.4 3.4 2.3 9.7 3.5 4.0 SRRM5 ENSG00000226763 "Serine/arginine repetitive matrix 5" B3KS81 19 43596617-43614498 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "testis: 47.8" "Group enriched" "Detected in some" 43 "Early spermatids: 176.5;Late spermatids: 64.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA047399, HPA052924" Uncertain Approved Vesicles,Centrosome NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles Centrosome "HPA047399: AB_10963088, HPA052924: " "unprognostic (3.95e-3)" "unprognostic (7.56e-3)" "unprognostic (6.72e-2)" "unprognostic (3.40e-2)" "unprognostic (1.38e-1)" "unprognostic (2.41e-2)" "unprognostic (1.10e-3)" "unprognostic (1.12e-1)" "unprognostic (8.02e-2)" "unprognostic (2.89e-2)" "unprognostic (3.69e-2)" "unprognostic (2.16e-2)" "unprognostic (2.68e-5)" "unprognostic (2.44e-1)" "unprognostic (3.31e-1)" "unprognostic (2.07e-1)" "unprognostic (1.00e-3)" 0.5 0.9 1.0 0.5 1.2 0.4 0.5 2.3 1.3 0.8 0.6 0.8 0.3 0.5 0.3 1.0 0.7 0.4 0.9 0.9 1.0 1.4 1.1 0.6 1.0 1.1 0.9 0.9 1.2 0.2 1.6 0.2 1.1 1.9 0.1 1.9 0.9 0.1 0.5 0.8 0.7 0.1 0.6 0.9 0.7 47.8 1.0 0.1 1.1 0.0 0.0 0.6 0.9 1.2 1.3 1.1 0.4 0.8 0.4 0.3 0.3 0.3 0.1 0.1 0.1 0.7 0.5 0.4 0.7 0.1 0.3 0.8 0.4 0.1 0.2 0.5 0.5 0.4 1.1 0.6 0.1 0.3 0.6 0.3 0.4 0.0 0.1 0.4 0.1 0.6 0.3 1.1 0.0 1.1 0.5 0.5 0.1 0.9 0.3 0.8 0.3 0.3 0.3 1.7 0.8 0.3 0.1 0.4 0.4 0.5 0.9 0.2 0.6 1.1 0.7 0.4 0.6 1.3 0.9 0.5 0.6 0.4 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.2 2.3 1.3 0.9 1.0 1.1 0.9 1.1 0.6 1.0 1.2 0.1 0.0 0.0 0.0 0.1 0.4 0.1 0.1 2.8 0.3 0.3 0.5 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 176.5 0.3 0.4 0.1 0.0 0.4 0.2 0.0 0.0 0.4 0.0 0.4 0.0 0.7 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.3 64.9 1.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.2 0.9 0.0 0.8 0.1 0.7 0.6 0.8 0.3 0.1 0.2 0.3 0.1 0.1 SSTR1 ENSG00000139874 "Somatostatin receptor 1" P30872 14 38207904-38213067 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0;intestine: 13.8;stomach 1: 21.7" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 18.1;Gastric mucus-secreting cells: 16.8;Hepatic stellate cells: 27.1;Oligodendrocyte precursor cells: 24.1;Paneth cells: 10.7;Proximal enterocytes: 11.8" "Cancer enhanced" "Detected in many" "prostate cancer: 5.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 118.9;BJ hTERT+: 32.5;BJ hTERT+ SV40 Large T+: 21.4;fHDF/TERT166: 70.7;HeLa: 26.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003207, HPA031506" Approved Uncertain Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "HPA003207: , HPA031506: AB_2673913" "unprognostic (1.40e-1)" "unprognostic (1.37e-1)" "unprognostic (3.36e-1)" "unprognostic (2.50e-3)" "unprognostic (4.34e-2)" "unprognostic (9.90e-2)" "unprognostic (3.66e-3)" "unprognostic (1.91e-1)" "unprognostic (6.16e-3)" "unprognostic (3.20e-2)" "unprognostic (1.72e-2)" "unprognostic (9.19e-2)" "prognostic favorable (4.28e-4)" "unprognostic (2.17e-1)" "unprognostic (1.67e-1)" "unprognostic (4.71e-2)" "unprognostic (3.28e-2)" 1.0 0.3 3.9 0.3 8.8 0.0 0.9 0.5 8.7 0.8 0.0 3.5 13.8 1.0 0.4 0.3 0.9 0.4 1.0 10.0 10.0 2.0 6.8 5.2 0.0 4.7 7.0 0.8 3.6 0.0 0.9 2.6 5.6 1.0 2.3 0.3 0.3 0.4 0.7 0.3 8.2 0.5 1.4 0.6 21.7 0.1 6.1 0.0 0.3 0.9 0.0 1.8 0.7 1.7 0.0 0.0 0.0 0.0 0.3 0.2 0.0 118.9 32.5 21.4 1.8 1.2 0.0 0.0 0.0 70.7 0.0 0.2 0.0 0.0 15.4 0.0 0.0 0.0 26.7 0.1 6.3 0.0 0.0 0.2 0.0 0.0 0.3 0.4 1.5 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.1 9.6 0.2 0.0 0.0 0.1 4.7 0.0 3.4 0.0 1.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 8.8 0.5 8.7 10.0 10.0 4.7 7.0 5.6 1.4 6.1 1.7 1.7 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 1.5 0.2 0.0 0.8 2.8 0.0 1.8 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 2.4 18.1 0.0 3.9 0.8 0.0 1.0 16.8 0.0 0.0 0.0 27.1 7.2 0.0 0.0 5.5 6.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.8 0.0 0.0 0.0 24.1 0.3 0.2 10.7 0.0 0.1 0.1 11.8 1.9 0.0 0.1 0.0 1.0 0.6 0.0 0.1 0.1 0.1 0.1 0.0 0.2 6.2 0.0 ST14 "HAI, MT-SP1, PRSS14, SNC19, TMPRSS14" ENSG00000149418 "ST14 transmembrane serine protease matriptase" Q9Y5Y6 11 130159782-130210362 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 144.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 489.4;Paneth cells: 327.2;Proximal enterocytes: 251.9;Undifferentiated cells: 216.9;Urothelial cells: 286.8" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "thalamus: 10.0" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 25.0" "Lineage enriched" "Detected in many" 5 "dendritic cells: 25.0" "Cell line enhanced" "Detected in many" "CACO-2: 224.2;CAPAN-2: 443.0;HaCaT: 311.4;OE19: 240.4;RPMI-8226: 301.2;SK-BR-3: 203.1;T-47d: 308.3;U-698: 218.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA047014, HPA056258" Enhanced Approved Nucleoplasm,Vesicles NA NA 1100000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles" "HPA047014: AB_2679902, HPA056258: " "unprognostic (1.17e-1)" "unprognostic (1.15e-1)" "unprognostic (9.62e-2)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (7.94e-2)" "unprognostic (1.20e-1)" "unprognostic (3.97e-2)" "unprognostic (5.29e-1)" "unprognostic (3.21e-1)" "unprognostic (1.03e-3)" "unprognostic (2.25e-1)" "prognostic favorable (5.03e-11)" "unprognostic (1.92e-2)" "unprognostic (2.71e-1)" "unprognostic (1.28e-2)" "unprognostic (5.60e-2)" 4.3 3.9 0.8 26.7 1.2 4.3 17.7 1.8 2.9 18.6 1.2 124.7 130.7 5.7 21.8 104.5 37.1 32.6 0.9 0.9 1.1 43.2 6.3 18.5 11.9 1.8 1.7 0.6 59.2 36.5 19.1 15.1 3.1 23.1 60.1 0.0 58.7 23.6 0.3 50.2 144.8 5.4 1.1 9.1 64.9 1.0 10.0 10.5 28.6 0.0 20.9 34.8 42.5 2.7 167.2 0.2 0.0 0.6 0.0 0.0 86.4 0.0 0.0 0.0 0.0 224.2 443.0 163.6 16.7 0.0 0.1 311.4 0.0 99.3 0.0 0.1 0.2 0.1 0.1 0.9 0.0 22.0 0.8 0.0 49.3 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 128.5 0.3 1.1 1.7 240.4 0.9 0.2 0.0 301.2 28.8 134.2 17.8 0.4 1.5 203.1 0.4 1.6 308.3 32.0 0.1 0.4 2.7 0.7 0.7 0.2 0.3 218.5 0.3 50.4 0.5 0.0 3.6 3.4 0.0 2.2 0.1 5.0 0.0 0.0 6.2 3.6 0.0 0.0 0.5 0.0 0.3 25.0 0.0 1.2 0.8 1.2 1.8 2.9 0.9 1.1 1.8 1.7 3.1 1.1 10.0 2.7 0.2 32.1 28.6 0.0 18.2 40.9 51.5 45.2 26.2 0.0 36.5 21.5 1.2 77.2 61.6 62.5 0.0 45.6 26.1 489.4 3.9 115.8 37.8 43.9 5.7 1.7 123.4 0.8 1.0 91.8 14.6 3.2 112.1 79.6 11.4 0.2 0.4 2.1 58.1 0.0 0.4 201.0 148.5 22.7 13.2 13.9 1.8 28.0 7.2 0.0 13.6 0.0 1.0 0.0 0.1 153.4 327.2 0.7 5.9 108.7 251.9 10.0 76.4 0.0 6.6 0.0 4.9 0.2 0.3 61.3 43.9 39.7 2.9 0.0 216.9 286.8 ST3GAL2 "SIAT4B, ST3GalA.2, ST3GALII" ENSG00000157350 "ST3 beta-galactoside alpha-2,3-sialyltransferase 2" Q16842 16 70375977-70439237 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 56.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 29.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017270 Approved Uncertain Vesicles "Intracellular and membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA017270: AB_1857523" "unprognostic (2.76e-2)" "unprognostic (6.33e-2)" "unprognostic (3.41e-1)" "unprognostic (1.35e-1)" "unprognostic (4.99e-1)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.79e-4)" "unprognostic (1.14e-2)" "unprognostic (2.21e-1)" "unprognostic (1.91e-2)" "prognostic favorable (2.33e-4)" "unprognostic (9.54e-2)" "prognostic unfavorable (3.34e-6)" "unprognostic (7.42e-2)" "unprognostic (8.83e-3)" "unprognostic (4.64e-2)" "unprognostic (5.20e-2)" 8.6 8.3 4.7 6.4 5.8 7.4 7.2 8.4 6.5 9.3 1.6 9.2 3.5 12.5 1.1 2.6 8.2 2.5 10.5 7.1 2.9 8.2 10.3 9.0 6.3 3.1 2.6 7.2 3.6 2.6 6.4 3.2 2.6 7.1 1.6 1.7 3.2 2.8 15.8 4.2 7.1 4.1 1.9 13.2 4.7 6.7 3.3 3.6 6.0 3.1 3.4 8.4 5.6 2.9 1.7 8.6 7.7 11.2 3.9 5.4 2.3 6.1 6.0 6.2 3.0 5.5 4.0 4.6 9.8 6.3 5.8 1.9 3.2 2.5 3.3 9.9 5.0 18.0 4.5 8.7 4.7 6.7 29.4 4.1 1.5 6.7 1.3 8.2 8.6 7.6 25.1 4.2 3.7 1.5 7.5 19.8 10.1 2.9 4.5 13.9 2.9 5.9 5.1 1.5 3.7 9.4 15.8 0.6 7.1 8.1 2.4 7.3 9.9 9.0 10.0 4.0 4.7 8.6 3.9 9.7 10.0 5.9 12.5 4.2 1.9 5.2 2.0 1.8 1.7 2.0 2.3 2.0 1.0 2.9 3.8 3.0 10.1 2.8 1.3 14.3 2.6 1.1 4.7 5.8 8.4 6.5 7.1 2.9 3.1 2.6 2.6 1.9 3.3 2.9 15.4 9.6 5.2 13.4 12.6 3.3 4.2 2.1 2.2 15.7 2.8 3.0 6.8 10.0 1.9 9.2 14.6 4.7 56.1 4.5 0.0 5.7 16.9 1.7 6.5 15.0 13.2 24.8 21.3 4.4 2.5 11.0 2.6 2.2 17.7 19.7 18.2 13.1 13.7 18.5 15.2 4.5 2.0 15.4 35.1 33.2 11.8 11.9 1.8 17.8 24.9 5.6 23.7 16.6 7.4 1.8 1.5 8.2 13.5 3.0 6.8 5.7 1.3 11.1 6.6 8.5 8.8 9.3 8.9 1.1 2.4 1.8 11.5 4.7 5.6 2.3 ST3GAL5 "SIAT9, SIATGM3S, ST3GalV" ENSG00000115525 "ST3 beta-galactoside alpha-2,3-sialyltransferase 5" Q9UNP4 2 85837120-85905199 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 47.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 112.8;Oligodendrocyte precursor cells: 94.0;Oligodendrocytes: 108.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 41.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 54.4;RT4: 47.0;SK-MEL-30: 40.8;U-266/84: 42.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034708, HPA040425, HPA068928" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "HPA034708: AB_10601594, HPA040425: AB_2676978, HPA068928: AB_2686060" "unprognostic (7.90e-2)" "unprognostic (1.61e-2)" "unprognostic (3.84e-2)" "unprognostic (2.93e-2)" "unprognostic (1.27e-1)" "unprognostic (1.75e-1)" "unprognostic (1.12e-2)" "unprognostic (5.81e-3)" "unprognostic (1.38e-1)" "unprognostic (6.45e-2)" "unprognostic (5.03e-3)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.25e-7)" "unprognostic (2.22e-1)" "unprognostic (5.74e-2)" "prognostic favorable (4.99e-4)" "prognostic favorable (4.48e-4)" 17.5 47.4 17.1 4.6 26.9 2.3 8.5 16.4 20.1 5.4 7.9 5.0 1.0 9.9 0.9 2.7 10.4 8.1 4.2 16.0 24.7 2.8 9.8 14.6 9.1 24.7 22.6 10.1 3.9 0.4 12.8 17.7 23.1 6.7 2.6 31.0 7.1 0.5 12.4 6.1 6.9 3.5 20.6 20.0 5.6 10.8 23.6 5.0 27.9 3.5 4.4 20.8 5.9 41.6 0.3 27.0 2.5 54.4 22.0 11.8 8.0 5.9 18.0 5.6 5.0 0.5 19.6 0.7 0.2 10.2 2.5 1.0 3.6 6.4 7.0 0.2 3.2 0.6 1.1 1.0 17.6 0.4 7.8 6.9 0.8 2.1 0.8 10.1 13.7 7.4 0.8 30.2 18.3 1.8 1.9 3.1 0.2 9.6 0.0 3.5 17.0 11.0 2.9 47.0 3.8 3.8 0.2 0.1 40.8 5.4 0.2 1.1 4.5 0.1 2.7 0.1 0.4 30.0 42.5 0.5 4.2 5.6 27.7 0.6 0.8 0.1 0.6 3.0 0.8 1.1 0.3 0.4 0.5 0.7 0.3 0.3 0.6 0.6 2.4 0.2 0.1 0.3 17.1 26.9 16.4 20.1 16.0 24.7 24.7 22.6 23.1 20.6 23.6 41.6 8.5 86.6 112.8 37.5 29.1 5.6 27.6 20.5 1.2 56.6 3.1 2.3 1.9 40.0 33.9 3.7 58.4 0.4 48.3 0.2 3.9 12.0 12.3 9.0 27.8 8.1 6.7 0.4 46.9 16.6 1.1 21.7 6.1 8.5 34.8 35.2 29.6 21.1 35.6 72.3 60.2 0.1 12.2 45.4 18.1 12.0 8.1 24.9 32.0 45.9 20.1 56.0 12.3 94.0 108.4 6.2 0.1 1.9 19.5 6.8 0.0 3.7 10.7 45.2 0.0 21.3 5.0 8.4 16.1 0.2 3.8 0.3 28.9 6.3 0.1 8.3 ST6GALNAC5 "MGC3184, SIAT7E, ST6GalNAcV" ENSG00000117069 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5" Q9BVH7 1 76867480-77067546 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5.9" "Group enriched" "Detected in some" 8 "Excitatory neurons: 480.3;Inhibitory neurons: 417.3" "Cancer enhanced" "Detected in many" "ovarian cancer: 10.9" "Region enhanced" "Detected in many" "cerebral cortex: 5.9;hippocampal formation: 5.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.7;fHDF/TERT166: 5.4;HaCaT: 2.7;SH-SY5Y: 4.1;U-2 OS: 4.4;U-251 MG: 2.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "hippocampal formation: 51.3" "HPA065593, HPA070354" Uncertain Approved Vesicles "Intracellular and membrane" NA Yes 180000 "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA065593: AB_2685515, HPA070354: AB_2686260" "unprognostic (1.32e-1)" "unprognostic (5.96e-2)" "unprognostic (1.72e-1)" "unprognostic (1.49e-2)" "unprognostic (2.82e-2)" "unprognostic (2.04e-2)" "unprognostic (4.67e-2)" "unprognostic (2.72e-2)" "unprognostic (3.60e-2)" "unprognostic (1.99e-1)" "unprognostic (1.61e-2)" "unprognostic (1.58e-1)" "unprognostic (2.10e-2)" "unprognostic (5.90e-3)" "unprognostic (9.66e-2)" "unprognostic (6.88e-2)" "unprognostic (1.69e-2)" 0.1 3.0 1.5 1.5 1.1 0.0 1.2 0.0 5.9 0.7 0.0 1.8 0.2 0.1 0.0 1.0 1.9 2.2 0.5 5.5 0.0 0.1 0.0 3.6 0.4 0.0 0.0 1.6 0.1 0.0 1.9 0.1 0.0 1.0 0.6 3.2 0.5 0.3 0.0 0.2 0.9 3.0 0.0 0.2 1.5 0.3 0.0 0.0 0.0 0.0 0.3 1.6 0.6 0.0 1.2 0.0 4.7 0.0 0.0 0.0 0.0 0.4 1.5 1.1 0.4 0.0 0.1 0.0 0.0 5.4 0.0 2.7 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.3 0.4 0.0 0.0 1.1 4.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 4.4 0.0 2.6 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.1 0.0 5.9 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.5 0.5 35.6 0.1 0.0 0.0 0.1 0.0 20.7 2.8 1.7 1.1 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.2 1.9 0.4 0.0 0.0 480.3 0.0 0.1 0.8 0.0 0.2 1.3 0.9 0.0 0.0 0.1 0.0 417.3 0.2 0.0 0.0 0.0 2.3 0.6 0.1 0.0 8.4 0.0 0.7 0.0 10.6 6.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 1.3 0.0 0.2 0.4 0.1 0.5 0.0 0.0 0.1 0.2 0.0 0.0 0.1 STAM STAM1 ENSG00000136738 "Signal transducing adaptor molecule" Q92783 10 17644151-17716824 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 53.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "T-reg: 76.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034399, HPA043882" Supported Supported Vesicles NA NA 82000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 24: Non-specific - Transcription regulation" Vesicles "CAB034399: AB_2197486, HPA043882: AB_2678713" "unprognostic (1.09e-2)" "unprognostic (8.32e-2)" "unprognostic (1.10e-1)" "unprognostic (3.95e-2)" "unprognostic (9.11e-3)" "unprognostic (1.04e-1)" "prognostic unfavorable (3.44e-6)" "unprognostic (1.39e-1)" "unprognostic (8.53e-2)" "unprognostic (8.58e-2)" "unprognostic (1.37e-2)" "unprognostic (8.39e-2)" "unprognostic (1.02e-3)" "unprognostic (1.39e-1)" "unprognostic (2.26e-1)" "unprognostic (1.87e-1)" "unprognostic (2.02e-1)" 10.8 13.3 7.7 6.9 9.7 53.1 8.9 14.0 11.8 10.7 3.4 8.0 8.2 9.0 5.8 12.2 7.8 9.1 18.0 9.2 8.7 10.2 6.9 10.9 7.5 9.8 9.5 11.4 10.4 10.3 7.4 8.5 9.8 8.7 7.7 11.2 8.5 6.1 24.5 10.0 7.3 8.5 9.6 6.8 11.4 8.1 9.1 13.1 10.8 10.1 7.5 10.9 9.0 14.7 34.8 19.8 30.8 14.2 30.1 21.9 10.3 45.1 19.8 41.0 33.1 25.9 31.7 9.1 7.2 33.9 31.7 18.2 27.6 21.1 35.0 10.9 12.7 86.3 15.3 43.1 31.8 6.5 43.7 22.7 27.0 33.6 28.3 26.6 19.8 56.3 30.1 10.5 43.8 10.4 35.7 5.6 14.7 19.7 10.2 18.0 29.0 11.9 17.5 11.2 13.0 19.2 24.6 16.7 34.6 24.1 27.5 9.4 26.6 23.9 24.5 42.7 21.1 6.6 11.5 15.6 25.6 9.6 15.6 47.5 7.5 12.5 5.9 8.2 5.6 5.4 12.8 6.2 9.6 3.1 8.8 7.1 5.9 17.3 7.5 5.5 76.5 6.4 7.7 9.7 14.0 11.8 9.2 8.7 9.8 9.5 9.8 9.6 9.1 14.7 13.2 12.8 23.4 15.7 14.1 22.9 5.3 16.2 23.9 19.7 9.4 8.9 30.0 5.7 14.0 16.5 10.4 10.2 24.3 6.4 5.9 15.1 3.5 16.3 22.3 11.0 11.4 56.8 31.7 13.4 10.5 23.5 15.8 25.9 31.6 13.0 10.4 7.8 15.5 10.1 36.9 7.8 2.0 10.4 16.3 3.5 9.6 15.6 19.6 39.4 8.4 13.7 10.3 31.7 59.4 29.9 8.0 6.0 20.8 10.1 5.7 15.6 14.0 14.5 26.3 22.3 12.6 22.1 14.6 21.8 21.0 24.6 27.6 18.4 8.1 8.5 STAM2 Hbp ENSG00000115145 "Signal transducing adaptor molecule 2" O75886 2 152116801-152175763 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 147.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 16.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035528, HPA035529" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "Nucleoplasm, Cytosol" "HPA035528: AB_10601606, HPA035529: AB_10672868" "unprognostic (1.53e-1)" "unprognostic (1.79e-1)" "unprognostic (4.81e-2)" "unprognostic (1.73e-1)" "unprognostic (2.31e-1)" "unprognostic (5.16e-2)" "unprognostic (2.76e-2)" "unprognostic (3.15e-2)" "unprognostic (6.54e-2)" "unprognostic (1.20e-1)" "unprognostic (1.22e-1)" "unprognostic (7.92e-2)" "unprognostic (1.11e-2)" "unprognostic (1.28e-1)" "unprognostic (1.76e-1)" "unprognostic (2.82e-1)" "unprognostic (1.03e-2)" 9.7 9.9 7.3 7.9 8.3 3.1 12.5 7.5 8.9 10.9 8.0 10.3 9.3 10.9 8.7 9.1 12.8 9.3 9.6 6.3 7.7 14.6 11.0 10.8 8.7 7.5 7.9 11.0 8.8 12.8 6.5 10.3 7.9 12.9 10.9 11.1 11.9 8.9 5.8 10.8 9.3 10.1 8.0 8.3 11.7 12.6 7.4 8.5 14.3 7.7 8.9 10.7 6.6 9.7 8.3 7.9 7.2 8.8 18.5 22.0 7.7 16.8 19.4 10.7 13.6 7.8 7.8 10.8 13.1 24.2 9.4 8.3 8.0 15.6 17.1 13.3 6.3 7.8 5.1 11.8 21.2 11.5 14.6 16.9 14.6 20.0 26.8 15.5 11.7 7.2 5.1 7.5 22.2 8.1 6.1 8.9 4.5 6.1 11.2 4.9 8.9 5.9 16.7 14.1 3.8 5.9 9.3 8.2 14.1 8.0 11.1 10.5 15.3 23.7 7.6 18.8 10.3 6.1 6.7 6.8 17.9 9.2 13.2 16.8 3.4 4.6 1.7 4.6 1.6 1.7 1.8 1.9 2.7 2.0 1.5 1.9 8.6 2.6 7.1 3.2 2.2 1.6 7.3 8.3 7.5 8.9 6.3 7.7 7.5 7.9 7.9 8.0 7.4 9.7 17.6 25.6 33.5 39.2 10.9 13.8 12.0 16.4 15.9 10.6 17.9 11.6 30.5 7.2 28.9 16.5 16.7 7.4 14.7 22.1 23.5 13.9 147.8 37.2 25.5 15.1 8.3 13.5 43.8 14.2 14.6 22.7 27.0 22.2 27.1 14.8 17.5 16.0 16.7 1.7 39.7 20.2 20.3 20.0 13.0 64.4 15.8 16.9 14.2 32.8 19.6 14.7 8.2 51.8 61.0 21.2 18.2 15.4 10.9 14.3 13.9 14.8 55.6 11.6 26.3 18.0 16.1 54.1 20.1 13.5 13.2 20.2 9.3 18.2 13.5 16.1 STAP1 "BRDG1, STAP-1" ENSG00000035720 "Signal transducing adaptor family member 1" Q9ULZ2 4 67558727-67607337 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 51.0" "Group enriched" "Detected in some" 5 "B-cells: 60.8;granulocytes: 80.8;Ionocytes: 65.1;Plasma cells: 147.2" "Cancer enriched" "Detected in many" 7 "renal cancer: 13.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory B-cell: 88.1;naive B-cell: 107.8" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Daudi: 185.4;U-698: 83.2" "Region enriched" "Detected in single" 5 "cerebellum: 2.3" "Low region specificity" "Detected in all" HPA038529 Enhanced Uncertain Nucleoplasm,Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Vesicles" "HPA038529: AB_10673011" "unprognostic (1.14e-4)" "unprognostic (1.49e-3)" "unprognostic (2.30e-2)" "unprognostic (2.17e-1)" "unprognostic (1.63e-3)" "unprognostic (6.30e-4)" "unprognostic (1.95e-3)" "unprognostic (6.95e-3)" "unprognostic (5.18e-2)" "unprognostic (6.38e-3)" "unprognostic (1.47e-1)" "unprognostic (8.43e-3)" "unprognostic (3.11e-2)" "unprognostic (1.49e-2)" "unprognostic (4.69e-2)" "unprognostic (2.71e-2)" "unprognostic (1.40e-1)" 0.4 0.1 0.0 15.5 0.0 5.8 0.8 0.0 0.0 0.3 0.0 2.3 1.8 0.6 1.9 0.7 0.1 1.4 0.2 0.5 0.0 9.2 0.4 1.4 40.8 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.9 2.3 0.0 1.3 2.8 0.1 0.1 8.1 0.4 0.0 16.0 2.3 2.7 0.0 6.4 0.4 0.0 51.0 1.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 185.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 24.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 5.4 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 83.2 0.0 24.7 0.0 5.3 0.1 24.3 0.9 0.1 1.9 88.1 2.0 0.8 1.2 107.8 7.9 0.2 1.0 38.9 0.1 5.2 0.4 4.7 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 5.7 0.0 60.8 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.7 5.5 0.0 0.0 5.8 0.0 9.8 0.0 13.0 0.1 0.0 0.6 0.0 2.5 0.3 0.0 0.0 0.1 0.0 0.0 80.8 0.0 0.4 0.0 0.8 0.0 0.2 0.1 65.1 0.3 0.7 7.1 0.3 1.2 16.0 0.0 0.2 0.0 6.2 0.0 0.3 0.0 0.0 0.4 147.2 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 3.7 0.2 0.1 0.1 0.0 4.3 0.1 0.0 0.2 STARD3 "es64, MLN64" ENSG00000131748 "StAR related lipid transfer domain containing 3" Q14849 17 39637090-39664201 "Cancer-related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "SK-BR-3: 260.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017021, HPA024307, HPA073948" Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Vesicles" "Endoplasmic reticulum" "CAB017021: , HPA024307: , HPA073948: " "unprognostic (1.11e-1)" "unprognostic (2.14e-2)" "unprognostic (6.35e-2)" "unprognostic (8.92e-3)" "unprognostic (2.09e-2)" "unprognostic (2.94e-1)" "prognostic unfavorable (3.60e-5)" "unprognostic (2.26e-1)" "unprognostic (1.77e-1)" "unprognostic (1.48e-1)" "unprognostic (6.25e-3)" "unprognostic (5.88e-2)" "prognostic unfavorable (7.70e-4)" "unprognostic (1.33e-1)" "unprognostic (5.22e-2)" "unprognostic (8.51e-3)" "unprognostic (3.00e-2)" 24.8 33.4 18.3 18.8 29.1 25.4 23.4 21.6 18.9 22.3 14.9 21.5 24.1 20.4 2.7 24.1 21.5 17.2 16.3 17.9 15.4 18.9 25.8 28.8 22.3 21.1 21.3 21.3 26.5 15.2 24.0 17.1 19.0 20.1 5.2 3.2 21.2 11.3 23.9 27.0 26.7 9.2 18.7 33.1 26.5 26.2 22.5 14.8 21.4 9.5 8.8 21.0 20.1 18.5 29.3 47.6 18.6 33.5 19.9 22.9 31.2 23.1 24.9 27.1 24.3 24.0 47.6 25.2 47.7 17.8 30.8 55.4 11.3 21.0 6.3 36.2 34.5 15.2 18.8 30.1 25.9 29.6 35.5 24.5 19.0 29.8 12.6 19.0 23.4 36.4 41.0 27.4 23.5 24.7 32.2 25.6 22.2 15.3 20.6 28.5 31.4 40.1 15.0 35.7 24.9 29.1 16.1 260.8 64.0 10.8 34.1 41.7 26.3 43.2 29.5 46.5 43.6 27.5 37.8 18.7 36.2 36.8 45.1 23.7 36.3 54.4 42.7 35.5 30.7 20.8 29.6 32.7 38.3 26.1 29.1 27.8 63.6 39.6 29.3 18.7 38.5 33.8 18.3 29.1 21.6 18.9 17.9 15.4 21.1 21.3 19.0 18.7 22.5 18.5 45.8 3.2 7.5 31.0 23.2 16.6 13.0 23.4 14.2 12.6 19.9 14.6 3.4 18.6 14.8 11.0 37.5 28.5 32.9 21.0 9.8 26.5 2.7 9.7 11.7 35.8 27.5 11.1 17.3 35.4 37.2 16.2 29.6 11.0 19.0 22.2 45.0 11.9 49.8 18.5 14.8 11.6 14.2 49.0 18.5 5.3 17.1 27.7 5.4 9.4 18.5 15.8 29.9 12.1 30.2 35.9 22.9 13.2 24.3 20.2 41.5 10.3 8.3 13.2 13.1 21.8 14.4 9.3 16.2 15.9 16.9 40.0 35.2 18.6 15.1 20.1 STARD3NL "MENTHO, MGC3251" ENSG00000010270 "STARD3 N-terminal like" O95772 7 38178245-38230670 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019204 Enhanced Supported Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA019204: AB_2197800" "unprognostic (1.55e-3)" "unprognostic (2.80e-3)" "unprognostic (2.22e-1)" "unprognostic (2.58e-1)" "unprognostic (4.37e-2)" "prognostic unfavorable (2.20e-4)" "prognostic unfavorable (1.44e-5)" "unprognostic (9.64e-2)" "unprognostic (1.89e-1)" "unprognostic (5.37e-2)" "prognostic favorable (8.48e-4)" "unprognostic (1.07e-1)" "unprognostic (2.97e-1)" "unprognostic (2.41e-2)" "unprognostic (8.09e-3)" "unprognostic (2.65e-1)" "unprognostic (8.71e-2)" 26.8 21.8 35.5 23.1 37.6 37.8 22.0 39.6 41.7 31.4 29.8 21.5 18.5 32.6 27.1 12.3 27.5 22.0 27.1 35.7 44.1 34.0 17.4 32.8 21.3 42.0 46.8 24.2 16.4 17.9 25.5 49.4 48.4 40.6 23.5 26.3 14.9 21.6 17.3 6.6 20.3 33.1 40.5 27.1 17.6 32.7 41.8 22.3 32.7 17.5 15.3 29.4 14.8 42.9 40.9 42.7 92.6 60.4 62.8 62.2 32.4 65.2 67.2 63.2 82.4 34.3 63.0 31.9 64.0 59.9 192.0 42.9 51.4 49.5 95.2 29.0 45.1 64.8 22.1 47.4 55.3 71.5 72.7 58.8 24.0 67.0 53.0 72.0 116.7 86.1 75.0 53.7 98.4 25.1 40.9 115.2 65.5 33.7 33.9 49.6 85.9 14.9 89.0 37.5 36.9 86.7 22.4 58.8 64.1 127.0 40.9 93.8 80.0 43.0 61.0 67.8 93.5 57.4 62.2 12.1 87.0 125.6 142.4 33.5 46.8 56.2 52.2 43.3 23.9 30.8 21.6 39.3 42.3 28.4 18.1 35.6 53.1 71.8 47.0 30.3 24.8 47.1 35.5 37.6 39.6 41.7 35.7 44.1 42.0 46.8 48.4 40.5 41.8 42.9 45.8 19.2 47.3 15.0 33.2 20.8 57.3 43.4 20.5 8.7 26.8 15.0 18.2 14.3 25.9 31.3 12.5 48.3 67.2 15.5 31.3 31.4 125.3 37.0 42.5 45.5 21.5 28.2 21.9 34.3 91.2 34.2 19.9 33.1 23.5 36.0 51.0 12.4 65.8 5.0 24.5 20.9 32.6 63.2 77.9 115.2 18.3 56.8 26.6 17.8 24.2 34.6 114.4 27.6 26.0 34.0 21.6 25.9 34.3 55.2 19.4 50.1 22.8 13.0 13.1 23.4 38.4 48.8 37.3 12.2 16.2 42.3 47.5 24.5 19.5 46.4 STARD5 MGC10327 ENSG00000172345 "StAR related lipid transfer domain containing 5" Q9NSY2 15 81309053-81324183 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 28.0;Plasma cells: 31.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 5.8;RPMI-8226: 6.2;U-266/70: 7.1;U-937: 6.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA040662 Approved Approved Vesicles,Cytosol NA NA "Cluster 44: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles Cytosol "HPA040662: AB_10959593" "unprognostic (5.35e-4)" "unprognostic (1.55e-1)" "unprognostic (2.58e-2)" "unprognostic (2.76e-1)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (2.22e-4)" "unprognostic (1.17e-1)" "unprognostic (2.36e-1)" "unprognostic (1.10e-2)" "unprognostic (2.08e-2)" "unprognostic (8.08e-2)" "unprognostic (6.81e-2)" "unprognostic (2.08e-2)" "unprognostic (1.46e-2)" "unprognostic (4.84e-3)" "unprognostic (7.55e-3)" 1.0 0.6 0.6 6.0 0.8 4.3 0.7 3.4 1.3 7.2 1.9 2.8 2.2 4.6 5.0 3.4 1.8 1.3 0.8 0.6 0.7 0.7 5.1 1.1 7.7 0.9 1.0 1.2 0.6 0.6 0.4 1.6 1.2 3.6 3.7 0.4 1.6 2.1 0.6 7.9 4.2 1.8 0.9 6.2 2.1 0.7 0.7 0.5 0.8 0.3 1.5 2.5 5.5 1.4 0.3 0.0 0.0 0.9 2.3 2.3 0.1 0.3 0.3 0.8 1.2 0.1 0.1 4.8 0.0 1.5 0.2 4.0 1.1 1.0 0.6 0.1 0.4 1.8 0.3 0.4 0.5 2.8 5.8 2.0 2.0 0.3 0.6 1.5 0.1 1.9 0.6 1.3 0.5 0.1 0.5 4.0 0.3 0.2 0.0 0.1 0.7 6.2 0.3 1.4 0.3 0.1 0.1 0.5 0.6 0.3 0.6 0.6 0.2 1.3 0.6 1.3 0.1 7.1 1.5 1.8 0.9 6.8 0.4 5.0 1.8 2.3 3.0 2.4 2.5 1.0 2.7 3.2 2.6 0.7 3.9 3.9 1.3 2.6 2.3 1.4 3.6 3.7 0.6 0.8 3.4 1.3 0.6 0.7 0.9 1.0 1.2 0.9 0.7 1.4 3.8 0.0 1.1 0.0 11.4 13.3 12.0 28.0 10.8 1.8 2.7 4.2 0.3 0.0 4.9 0.0 6.2 2.5 4.2 22.1 3.9 1.3 15.2 2.5 14.4 2.5 11.4 2.5 2.2 1.4 4.0 8.5 15.8 2.3 10.2 1.0 3.6 25.4 5.2 1.7 2.0 24.3 2.0 7.9 10.9 1.5 5.0 8.0 1.8 1.9 0.7 1.2 2.1 0.0 0.4 1.8 14.4 9.8 31.5 3.3 23.9 0.7 4.0 0.9 0.0 3.8 2.8 0.9 0.7 19.6 16.3 4.9 4.2 6.3 19.9 9.6 STEAP2 "IPCA-1, PCANAP1, STAMP1, STMP" ENSG00000157214 "STEAP2 metalloreductase" Q8NFT2 7 90167590-90238137 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "prostate: 127.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 68.0;Inhibitory neurons: 53.0;Prostatic glandular cells: 102.9" "Cancer enriched" "Detected in many" 12 "prostate cancer: 88.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 22.5;CAPAN-2: 48.1;U-138 MG: 27.4" "Low region specificity" "Detected in all" "HPA029115, HPA055603" Uncertain Supported Vesicles NA NA "Cluster 51: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 35: Glandular cells - Unknown function" Vesicles "HPA029115: AB_10603894, HPA055603: " "unprognostic (6.26e-3)" "unprognostic (2.48e-1)" "unprognostic (2.55e-1)" "unprognostic (1.65e-1)" "unprognostic (8.20e-4)" "unprognostic (2.34e-1)" "unprognostic (1.13e-1)" "unprognostic (3.67e-3)" "unprognostic (7.91e-2)" "unprognostic (1.70e-1)" "unprognostic (9.92e-2)" "unprognostic (1.34e-1)" "unprognostic (2.71e-2)" "unprognostic (9.73e-2)" "unprognostic (6.11e-2)" "unprognostic (9.86e-5)" "unprognostic (3.69e-2)" 20.0 3.7 7.3 11.9 10.4 0.0 13.0 8.3 18.5 9.5 6.9 15.1 6.1 7.1 2.7 6.9 14.3 10.1 15.1 11.2 6.9 6.8 4.0 20.5 0.4 3.1 5.0 17.2 8.1 10.1 19.4 0.2 3.8 127.7 7.6 3.9 11.9 6.9 1.4 4.7 9.1 10.8 5.4 2.7 11.0 1.1 6.4 3.3 7.9 1.6 1.7 15.8 9.0 5.7 3.2 22.5 0.5 6.3 11.5 11.1 0.3 2.8 5.8 0.4 0.8 4.2 48.1 0.0 0.3 7.5 8.8 1.8 4.9 3.5 0.8 0.0 4.7 0.0 0.1 1.1 1.0 0.0 0.1 8.1 0.8 11.5 2.3 9.4 6.1 0.0 0.0 0.4 6.6 0.0 0.0 0.7 9.1 0.0 2.5 0.0 0.0 0.2 10.3 6.6 0.7 2.1 3.5 0.0 0.1 1.0 16.8 0.0 5.1 27.4 6.0 3.8 2.4 0.1 0.0 0.0 11.7 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.3 10.4 8.3 18.5 11.2 6.9 3.1 5.0 3.8 5.4 6.4 5.7 0.6 0.0 1.1 18.6 0.2 4.8 21.6 20.6 9.1 7.5 16.1 10.3 18.0 18.6 19.4 12.9 2.1 0.0 0.1 15.9 0.0 1.1 0.5 2.8 3.7 2.2 15.7 2.7 68.0 7.4 0.0 27.6 10.7 2.9 0.0 30.4 3.6 5.8 0.0 1.7 53.0 9.8 10.2 0.0 6.2 0.8 15.5 0.7 0.0 2.8 0.0 23.1 0.0 27.6 2.6 11.4 24.0 15.4 0.0 102.9 13.1 10.8 16.0 1.3 0.0 14.7 5.8 3.1 6.2 4.1 5.4 0.0 0.5 9.8 13.8 25.3 STK11IP "KIAA1898, LIP1, LKB1IP, STK11IP1" ENSG00000144589 "Serine/threonine kinase 11 interacting protein" Q8N1F8 2 219597857-219616451 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 15.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036837, HPA036838, HPA053192" Approved Enhanced Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA036837: AB_10969754, HPA036838: AB_10672100, HPA053192: AB_2682075" "unprognostic (3.37e-1)" "unprognostic (1.33e-1)" "unprognostic (3.51e-1)" "unprognostic (1.97e-1)" "unprognostic (2.15e-1)" "unprognostic (3.33e-3)" "unprognostic (1.22e-3)" "unprognostic (8.36e-2)" "unprognostic (9.36e-2)" "unprognostic (1.87e-2)" "prognostic favorable (1.63e-4)" "unprognostic (9.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.80e-3)" "unprognostic (9.44e-2)" "unprognostic (1.02e-1)" "unprognostic (2.51e-2)" 7.6 10.0 12.0 9.5 12.4 19.5 7.1 11.3 13.8 9.2 12.6 9.8 9.2 9.2 15.0 9.6 10.4 9.5 8.0 12.4 10.6 11.2 5.9 9.3 14.0 12.0 11.9 24.5 9.5 7.5 21.5 8.2 12.3 9.9 7.8 12.3 8.1 6.5 5.8 18.4 10.0 8.3 10.0 15.1 8.6 31.2 12.0 19.5 11.1 4.3 11.1 9.0 8.3 11.8 10.1 15.4 16.1 11.0 5.6 9.9 16.5 8.7 7.6 13.9 11.7 14.3 16.7 5.8 8.7 8.4 12.6 24.4 7.7 18.7 10.3 8.7 11.7 15.1 17.2 11.6 7.4 15.9 38.2 9.6 16.5 11.7 5.9 14.2 8.6 9.7 11.4 8.5 7.9 19.7 9.3 19.6 16.2 4.8 8.4 17.5 5.9 4.5 13.8 15.8 10.6 16.8 5.7 13.8 12.0 12.9 8.8 15.3 6.5 15.0 12.6 14.5 8.6 9.4 4.5 10.8 11.4 8.7 9.5 1.5 4.3 5.3 2.6 5.8 2.1 1.7 1.2 2.1 7.7 1.2 1.0 1.0 1.4 3.7 6.5 15.1 2.1 2.6 12.0 12.4 11.3 13.8 12.4 10.6 12.0 11.9 12.3 10.0 12.0 11.8 3.5 6.4 6.7 12.4 3.9 2.3 2.1 6.3 1.2 7.8 5.1 5.5 3.6 1.5 7.8 7.3 18.8 10.0 10.3 14.6 1.9 5.0 14.0 11.9 4.0 4.6 13.1 6.9 10.7 6.5 5.6 5.3 17.3 5.8 12.7 29.7 4.2 3.3 8.4 11.8 8.0 8.8 6.1 8.6 5.7 30.9 25.4 8.9 3.6 8.4 7.0 4.9 4.1 8.5 7.4 4.2 3.3 14.7 2.8 1.7 5.4 2.7 19.9 12.6 13.1 3.2 4.9 18.5 13.8 3.5 2.7 16.1 4.5 5.4 8.8 2.8 STK39 "DCHT, SPAK" ENSG00000198648 "Serine/threonine kinase 39" Q9UEW8 2 167954020-168247595 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 159.9;Inhibitory neurons: 142.9;Oligodendrocyte precursor cells: 153.3;Oligodendrocytes: 359.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046022, HPA061803, HPA062802" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA 80000 "Cluster 35: T-regs - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Vesicles, Cytosol" "CAB046022: AB_2196960, HPA061803: AB_2684616, HPA062802: AB_2684870" "prognostic favorable (3.96e-4)" "unprognostic (2.97e-2)" "unprognostic (4.40e-2)" "unprognostic (4.22e-2)" "unprognostic (4.36e-1)" "unprognostic (6.14e-2)" "prognostic unfavorable (5.67e-5)" "unprognostic (3.04e-2)" "unprognostic (8.86e-2)" "unprognostic (9.43e-2)" "unprognostic (3.20e-2)" "unprognostic (1.38e-1)" "unprognostic (2.06e-1)" "unprognostic (9.45e-2)" "unprognostic (8.61e-3)" "unprognostic (1.14e-1)" "unprognostic (6.20e-3)" 19.4 6.7 20.1 14.0 25.8 5.1 8.4 25.3 25.1 12.0 52.9 26.3 32.0 7.3 14.5 36.3 6.4 18.1 15.8 16.0 18.6 9.0 1.9 7.6 22.2 28.8 25.8 6.6 25.6 13.7 8.2 2.3 31.9 28.7 32.4 27.8 67.9 11.5 2.7 6.3 18.6 11.7 20.8 8.6 31.8 48.5 25.6 29.1 6.9 7.6 23.5 24.8 9.5 37.0 19.1 10.9 40.9 12.9 28.1 37.5 4.0 45.0 33.8 29.6 27.8 0.2 59.9 51.1 12.2 30.5 25.5 46.6 26.7 34.4 37.1 16.2 16.4 21.2 11.8 42.9 52.3 30.5 2.1 29.1 52.8 35.1 36.5 38.5 21.2 41.3 0.5 0.0 67.0 11.4 51.6 13.0 30.3 41.0 24.3 72.1 16.0 4.8 27.9 47.6 65.7 27.0 15.7 2.6 21.8 20.3 8.0 25.9 20.2 36.6 11.1 26.5 32.2 0.1 0.0 41.5 29.7 28.5 25.1 0.0 0.3 0.0 1.1 0.2 0.6 0.2 0.9 1.6 0.5 0.5 0.2 0.8 0.0 1.0 0.1 0.1 1.8 0.2 20.1 25.8 25.3 25.1 16.0 18.6 28.8 25.8 31.9 20.8 25.6 37.0 6.1 3.2 14.0 64.6 6.4 3.8 34.4 6.5 5.7 14.8 5.5 6.5 26.2 18.6 15.2 5.5 16.7 0.1 30.0 47.7 21.5 10.9 29.4 11.9 11.6 5.6 22.8 5.7 159.9 23.1 0.1 9.2 28.1 18.9 0.0 5.8 2.9 0.4 3.5 20.2 142.9 17.3 14.2 6.7 6.7 16.2 10.2 6.7 17.8 64.6 5.5 28.9 12.3 153.3 359.4 36.0 20.1 11.3 9.5 74.8 14.5 7.9 17.5 30.0 6.6 7.7 18.2 25.4 8.1 7.5 4.4 0.3 19.4 15.8 22.4 50.6 STMN2 "SCG10, SCGN10" ENSG00000104435 "Stathmin 2" Q93045 8 79611117-79666158 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 524.1" "Group enriched" "Detected in some" 4 "Excitatory neurons: 182.2;Horizontal cells: 148.0;Inhibitory neurons: 133.0;Rod photoreceptor cells: 53.4" "Group enriched" "Detected in many" 5 "glioma: 26.1;pancreatic cancer: 10.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "plasmacytoid DC: 2.2" "Lineage enriched" "Detected in single" 13 "dendritic cells: 2.2" "Cell line enriched" "Detected in some" 9 "SH-SY5Y: 663.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026922 Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "Endoplasmic reticulum" "HPA026922: AB_1857605" "unprognostic (4.41e-1)" "unprognostic (3.35e-2)" "unprognostic (1.01e-1)" "unprognostic (2.49e-1)" "unprognostic (8.20e-2)" "unprognostic (9.48e-2)" "unprognostic (1.82e-1)" "unprognostic (6.08e-2)" "unprognostic (1.32e-1)" "unprognostic (1.71e-1)" "unprognostic (1.15e-1)" "unprognostic (1.70e-1)" "unprognostic (1.29e-13)" "unprognostic (1.14e-1)" "unprognostic (3.86e-1)" "unprognostic (5.77e-3)" "unprognostic (9.59e-2)" 5.8 68.6 161.3 9.6 148.3 0.1 2.8 162.9 524.1 8.4 0.0 22.0 13.9 1.1 0.0 1.0 0.1 3.5 1.0 135.7 343.1 0.2 0.9 0.3 0.7 213.6 140.1 0.5 4.7 0.0 8.9 0.1 257.5 2.6 28.9 87.0 0.9 1.7 0.3 11.5 18.5 6.3 60.9 4.5 5.4 1.9 148.2 0.3 0.2 0.3 1.4 0.4 5.0 165.0 0.0 0.0 5.6 0.0 0.9 0.2 0.3 72.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 59.6 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 64.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 1.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 60.5 663.5 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.2 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 161.3 148.3 162.9 524.1 135.7 343.1 213.6 140.1 257.5 60.9 148.2 165.0 0.1 0.0 0.0 26.1 0.0 1.0 0.0 0.0 0.0 27.8 0.0 0.3 0.1 0.0 0.0 0.0 6.2 0.1 0.0 0.0 0.0 0.0 18.2 0.0 1.5 1.4 24.9 0.0 182.2 0.0 0.5 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.9 148.0 133.0 0.0 0.0 0.0 2.0 8.2 0.3 0.0 1.8 19.7 0.0 16.3 0.0 19.1 23.5 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 53.4 0.0 0.0 0.6 0.5 0.7 0.0 0.9 0.0 0.1 0.0 0.0 0.5 STMN4 RB3 ENSG00000015592 "Stathmin 4" Q9H169 8 27235323-27258420 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 333.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 45.6;Horizontal cells: 92.5;Oligodendrocyte precursor cells: 27.6;Oligodendrocytes: 217.4" "Cancer enriched" "Detected in some" 27 "glioma: 14.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 26 "SCLC-21H: 86.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027765 Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Golgi apparatus" Vesicles "HPA027765: AB_1857607" "unprognostic (1.52e-1)" "unprognostic (3.45e-2)" "unprognostic (2.37e-2)" "unprognostic (3.19e-6)" "unprognostic (1.22e-1)" "unprognostic (1.97e-1)" "unprognostic (8.27e-2)" "unprognostic (1.37e-1)" "unprognostic (3.57e-3)" "unprognostic (2.36e-1)" "unprognostic (2.31e-3)" "unprognostic (9.84e-2)" "unprognostic (1.68e-3)" "unprognostic (1.37e-2)" "unprognostic (5.96e-2)" "unprognostic (4.15e-1)" "unprognostic (7.63e-2)" 0.3 10.2 128.0 0.2 147.2 0.1 0.2 154.9 333.3 0.5 66.3 4.3 0.6 0.4 0.9 0.1 0.3 0.2 0.1 148.1 150.9 0.1 0.1 0.1 0.0 185.1 152.3 0.2 0.1 0.0 1.1 0.0 184.4 0.5 1.4 21.4 0.1 0.2 0.2 0.4 1.6 0.6 151.1 0.0 0.9 0.6 150.9 0.0 0.1 0.0 0.0 0.6 0.6 265.7 0.0 0.1 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 86.8 3.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 128.0 147.2 154.9 333.3 148.1 150.9 185.1 152.3 184.4 151.1 150.9 265.7 0.1 0.0 0.0 4.6 0.0 0.4 0.1 0.0 0.0 45.6 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 0.0 21.4 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 92.5 18.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 5.6 0.0 9.7 0.0 27.6 217.4 0.0 0.0 1.5 0.0 0.3 0.0 0.0 0.0 13.4 0.0 0.0 0.2 0.8 3.4 0.0 0.1 0.0 0.0 0.0 0.0 0.5 STOM "BND7, EPB7, EPB72" ENSG00000148175 Stomatin P27105 9 121338987-121370304 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 454.6;Erythroid cells: 535.1;Hepatocytes: 371.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 591.3;hTCEpi: 497.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010961, HPA011419" Approved Enhanced "Vesicles,Plasma membrane,Cytosol" NA NA 16000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 30: Epithelial cell lines - Translation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cytosol" "HPA010961: AB_1080111, HPA011419: AB_1080109" "unprognostic (1.11e-1)" "unprognostic (2.15e-2)" "unprognostic (5.27e-2)" "unprognostic (7.93e-2)" "unprognostic (5.68e-3)" "unprognostic (1.65e-2)" "unprognostic (9.20e-3)" "unprognostic (7.86e-2)" "unprognostic (1.76e-1)" "unprognostic (3.59e-2)" "unprognostic (3.32e-1)" "unprognostic (1.26e-1)" "unprognostic (5.23e-2)" "unprognostic (9.15e-3)" "unprognostic (2.27e-2)" "unprognostic (7.82e-2)" "unprognostic (2.99e-2)" 339.0 117.3 100.4 101.0 108.1 358.2 243.8 94.7 103.9 129.3 74.8 226.0 46.1 139.9 72.2 87.8 141.7 153.3 219.7 90.5 113.1 123.9 355.4 290.7 67.7 120.7 115.1 81.3 38.9 45.3 49.8 272.7 108.9 111.6 58.4 15.0 95.5 93.4 102.6 118.3 114.1 155.9 105.2 121.6 139.3 24.7 111.0 33.8 112.9 106.2 46.4 182.4 129.6 108.7 8.4 55.0 4.8 26.0 591.3 170.3 0.4 138.6 149.3 40.7 64.5 7.6 10.8 66.5 34.3 186.6 23.9 14.7 31.7 133.0 79.3 41.7 12.0 144.7 108.8 23.1 299.0 61.4 32.4 272.2 497.3 60.9 88.0 11.7 152.5 21.0 33.3 88.2 96.8 45.2 2.2 47.0 64.4 3.5 16.6 8.7 0.2 147.7 34.7 1.7 5.9 0.5 114.5 107.8 62.1 44.9 36.6 47.4 172.8 92.0 28.1 91.3 13.6 36.5 44.9 4.4 35.1 58.1 51.0 21.4 35.5 4.1 168.9 55.8 165.7 5.9 84.2 153.3 35.8 4.2 15.0 81.1 20.8 147.1 41.0 6.1 8.7 128.8 100.4 108.1 94.7 103.9 90.5 113.1 120.7 115.1 108.9 105.2 111.0 108.7 454.6 160.3 96.6 30.0 13.2 105.5 251.8 107.0 62.0 5.0 135.8 72.3 36.7 121.5 159.0 35.0 6.2 121.9 72.1 26.3 3.9 56.6 3.6 97.0 75.4 313.6 0.0 535.1 3.2 22.0 54.7 140.3 17.9 11.7 36.1 76.0 282.7 371.2 92.1 3.3 4.8 1.1 54.9 226.3 92.3 9.0 66.5 105.9 88.9 70.3 37.9 8.6 127.7 6.6 4.5 39.1 18.3 103.0 16.9 90.2 33.8 92.8 216.0 5.0 138.1 73.2 188.1 40.8 13.7 48.4 119.1 172.8 98.8 81.8 2.2 200.0 STPG3 "C9orf173, FLJ40246" ENSG00000197768 "Sperm-tail PG-rich repeat containing 3" Q8N7X2 9 137251261-137253483 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 42.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 3.3;RPMI-8226: 1.4;SK-BR-3: 1.2;T-47d: 2.0;U-266/70: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA044352 Uncertain Vesicles NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA044352: AB_10965328" "unprognostic (1.20e-1)" "unprognostic (5.32e-2)" "unprognostic (4.32e-3)" "unprognostic (4.72e-4)" "unprognostic (2.56e-1)" "unprognostic (1.22e-2)" "unprognostic (1.08e-2)" "unprognostic (2.77e-3)" "unprognostic (1.29e-1)" "unprognostic (3.93e-2)" "unprognostic (8.59e-4)" "unprognostic (2.09e-1)" "unprognostic (7.25e-2)" "unprognostic (2.65e-1)" "unprognostic (1.58e-1)" "unprognostic (1.29e-1)" "unprognostic (7.95e-2)" 0.9 0.5 0.0 0.4 0.0 0.3 0.2 0.2 0.1 0.3 0.0 0.1 3.9 0.2 0.2 0.1 0.4 0.2 0.2 0.0 0.1 1.1 1.5 0.1 0.4 0.1 0.1 0.0 1.3 0.0 0.7 0.2 0.1 0.3 0.0 1.5 1.3 0.0 0.0 0.6 3.0 0.0 0.1 0.4 0.5 42.5 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.9 0.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 3.3 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.6 0.4 0.0 0.8 0.0 0.1 0.0 0.2 0.2 0.0 0.0 1.4 0.0 0.0 0.4 0.2 0.1 1.2 0.0 0.2 2.0 0.0 0.0 0.3 0.6 0.1 0.0 1.2 0.7 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 STX10 "hsyn10, SYN10" ENSG00000104915 "Syntaxin 10" O60499 19 13144058-13150383 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035303, HPA056439" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Vesicles" "HPA035303: AB_10671932, HPA056439: AB_2683135" "unprognostic (1.72e-2)" "unprognostic (2.26e-2)" "unprognostic (1.62e-2)" "unprognostic (6.73e-2)" "unprognostic (2.40e-1)" "unprognostic (1.21e-2)" "unprognostic (2.54e-3)" "prognostic favorable (8.26e-4)" "unprognostic (4.09e-1)" "unprognostic (3.66e-2)" "unprognostic (4.57e-2)" "unprognostic (9.21e-2)" "prognostic unfavorable (1.69e-7)" "unprognostic (2.39e-3)" "unprognostic (7.95e-2)" "unprognostic (2.23e-1)" "unprognostic (2.98e-2)" 45.3 58.7 42.1 35.6 44.3 72.3 47.1 45.3 52.3 65.5 47.0 57.2 47.7 48.7 17.1 80.7 49.6 29.5 56.1 42.2 41.7 60.9 78.8 66.9 42.5 44.6 43.3 50.7 48.3 27.9 49.1 17.0 43.1 49.9 19.8 11.6 52.0 20.4 35.8 68.2 60.7 20.9 40.7 87.0 60.3 17.7 43.6 35.3 56.6 16.6 28.2 51.4 55.4 48.5 99.9 68.8 51.8 138.1 51.5 52.8 17.2 55.4 49.4 46.1 48.4 31.8 88.3 66.5 80.5 66.8 33.7 76.3 44.9 67.0 26.6 113.4 86.0 60.8 154.4 66.5 38.2 71.4 63.2 54.3 55.3 57.4 37.2 62.8 58.1 85.9 32.9 34.6 31.8 87.2 105.6 125.2 55.2 51.3 112.5 117.3 54.1 96.6 44.4 47.2 60.0 121.3 57.9 66.2 127.6 14.9 45.1 67.9 58.4 75.3 38.7 145.9 77.5 78.1 75.2 57.0 98.0 172.8 59.8 41.5 162.3 120.4 48.1 128.4 40.7 39.9 41.4 48.7 119.1 40.3 36.3 37.3 267.6 32.1 151.5 31.2 51.4 80.7 42.1 44.3 45.3 52.3 42.2 41.7 44.6 43.3 43.1 40.7 43.6 48.5 31.6 16.0 21.6 13.1 29.9 35.4 34.5 52.0 31.3 21.3 43.0 37.5 12.6 30.0 53.6 20.2 6.2 17.7 32.2 54.3 27.4 42.5 1.0 23.9 28.3 31.3 16.3 33.2 16.6 56.1 26.2 27.6 40.8 24.7 53.8 33.7 31.1 18.8 82.4 13.5 11.8 48.0 46.8 86.7 45.8 3.0 25.1 62.0 48.0 7.5 86.1 21.4 48.4 11.1 14.0 57.0 53.8 31.2 25.3 19.9 77.9 28.3 38.2 17.1 26.3 21.2 31.0 9.0 16.2 38.6 43.2 19.4 39.1 23.6 55.5 38.4 STX12 "STX13, STX14" ENSG00000117758 "Syntaxin 12" Q86Y82 1 27773219-27824443 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041038, HPA055300" Approved Enhanced "Nucleoplasm,Golgi apparatus,Vesicles" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA041038: AB_10794261, HPA055300: AB_2682778" "unprognostic (3.47e-1)" "unprognostic (1.27e-1)" "unprognostic (1.60e-1)" "unprognostic (8.16e-3)" "unprognostic (2.83e-1)" "unprognostic (2.85e-1)" "unprognostic (1.26e-2)" "unprognostic (3.52e-1)" "unprognostic (1.14e-2)" "unprognostic (2.78e-2)" "unprognostic (9.35e-2)" "unprognostic (3.55e-1)" "unprognostic (1.91e-2)" "unprognostic (8.43e-2)" "unprognostic (2.06e-1)" "unprognostic (1.47e-1)" "unprognostic (2.24e-1)" 64.2 30.1 38.1 26.6 39.0 10.8 37.0 40.8 45.6 28.8 25.4 30.7 36.3 30.9 62.9 39.2 23.9 39.8 20.9 37.3 41.7 35.2 29.1 50.0 25.6 42.0 45.3 22.1 30.3 46.5 26.6 33.3 43.6 30.7 32.5 43.2 26.9 32.1 21.4 27.0 32.8 35.9 42.2 30.5 65.5 13.4 38.4 17.3 94.7 27.1 22.2 39.1 23.4 44.6 23.2 10.9 28.8 19.0 53.9 65.0 14.8 47.9 70.3 43.1 48.5 13.5 29.5 25.2 49.6 64.6 18.5 19.0 19.2 23.9 42.9 22.2 22.8 14.4 12.0 13.7 42.2 16.1 29.0 61.3 28.7 60.6 34.5 35.3 70.3 14.3 19.1 24.6 47.7 8.5 13.7 12.3 12.1 34.3 15.3 8.7 23.1 15.5 38.1 37.5 32.3 17.6 22.4 19.3 35.2 23.3 13.1 14.0 76.2 21.9 12.5 50.0 16.6 14.5 11.2 14.3 35.1 24.1 31.2 24.6 35.7 13.7 6.1 39.4 10.6 13.6 7.3 9.7 25.2 10.8 8.1 6.8 16.5 9.2 40.6 12.4 7.9 17.4 38.1 39.0 40.8 45.6 37.3 41.7 42.0 45.3 43.6 42.2 38.4 44.6 93.0 54.5 36.3 25.1 43.6 109.4 97.2 30.7 51.2 46.2 42.0 25.7 18.9 30.0 40.8 57.0 31.3 30.0 28.3 82.8 37.2 51.9 2.0 34.7 33.1 71.1 41.3 17.7 70.9 58.4 33.5 53.2 108.6 49.4 22.8 26.7 47.8 20.4 50.6 26.9 65.7 29.5 14.2 91.4 77.7 4.2 36.1 62.3 53.4 56.2 41.3 67.9 36.0 34.7 59.1 68.4 58.6 47.4 33.9 74.9 51.3 69.7 27.4 51.2 39.5 45.7 57.5 20.0 20.1 69.9 99.2 78.0 31.6 54.0 29.9 99.9 STX16 "hsyn16, SYN16" ENSG00000124222 "Syntaxin 16" O14662 20 58651253-58679526 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041019, HPA042033" Uncertain Enhanced Vesicles NA NA "Cluster 34: Basophils - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" Vesicles "HPA041019: AB_10964273, HPA042033: AB_10963935" "unprognostic (7.52e-2)" "unprognostic (1.91e-1)" "unprognostic (7.96e-2)" "unprognostic (1.35e-2)" "unprognostic (1.51e-1)" "unprognostic (2.12e-1)" "prognostic unfavorable (4.18e-4)" "unprognostic (7.32e-2)" "unprognostic (5.11e-2)" "unprognostic (3.51e-2)" "unprognostic (2.80e-3)" "unprognostic (2.41e-2)" "prognostic unfavorable (1.11e-16)" "unprognostic (3.35e-2)" "unprognostic (1.53e-1)" "unprognostic (1.56e-1)" "unprognostic (5.89e-2)" 39.5 44.5 42.3 34.7 43.6 54.3 42.7 38.8 45.5 60.9 36.8 56.4 26.2 50.1 44.6 40.8 58.9 24.9 38.5 39.1 39.5 47.6 45.9 44.2 46.3 44.4 42.1 58.9 50.0 21.2 68.7 26.4 44.4 52.7 26.0 38.7 43.5 30.0 33.3 53.7 49.3 27.8 39.4 65.3 44.3 36.3 42.5 33.0 49.2 19.5 32.4 55.5 49.5 50.8 37.2 21.4 27.6 26.9 49.7 52.6 38.2 45.1 30.5 45.3 28.0 41.9 53.0 42.5 61.3 32.4 56.7 53.9 25.5 53.6 37.3 20.2 26.9 26.6 63.9 51.3 49.2 38.2 57.8 58.9 80.4 30.5 46.0 84.6 46.4 49.2 31.3 36.8 36.9 86.9 29.8 45.9 11.2 30.1 35.9 27.3 25.8 29.6 34.6 27.3 18.2 27.7 47.7 82.8 83.2 46.4 33.1 50.1 49.5 74.1 36.0 28.6 50.3 75.7 37.7 23.4 54.7 29.2 31.7 18.2 5.8 5.0 4.3 5.3 4.8 2.3 3.9 3.1 3.8 3.7 5.1 4.9 12.6 5.4 3.9 3.9 4.7 4.1 42.3 43.6 38.8 45.5 39.1 39.5 44.4 42.1 44.4 39.4 42.5 50.8 40.2 22.4 46.6 0.0 27.0 26.9 19.3 22.8 29.0 65.2 44.3 41.5 24.3 41.5 31.2 29.5 85.5 24.2 33.7 23.4 5.9 16.6 6.2 32.6 51.2 36.3 46.1 26.5 0.0 13.7 20.6 28.3 38.2 26.1 19.6 54.8 37.1 30.8 22.2 42.1 0.0 25.4 20.3 42.9 35.9 8.9 22.7 37.1 21.4 0.0 44.0 29.5 33.0 0.0 0.0 19.7 22.5 29.0 16.2 20.1 30.0 12.5 45.6 52.8 13.1 32.1 30.4 47.5 20.2 35.2 42.3 17.5 42.6 27.8 26.0 21.5 STX1A "HPC-1, p35-1, STX1" ENSG00000106089 "Syntaxin 1A" Q16623 7 73699206-73719672 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Exocytosis, Neurotransmitter transport, Transport" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "brain: 128.5;pituitary gland: 98.5" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 52.7;Excitatory neurons: 60.6;Pancreatic endocrine cells: 29.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 139.9;U-87 MG: 92.2" "Group enriched" "Detected in all" 5 "amygdala: 246.2;basal ganglia: 93.9;cerebral cortex: 354.4;hippocampal formation: 229.1;white matter: 116.1" "Group enriched" "Detected in all" 8 "amygdala: 37.6;cerebral cortex: 103.4;hippocampal formation: 87.2" "CAB008372, HPA069176" Enhanced Approved "Nuclear membrane,Vesicles" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "Nuclear membrane" "CAB008372: AB_592786, HPA069176: AB_2686098" "unprognostic (5.12e-3)" "prognostic unfavorable (3.63e-4)" "unprognostic (3.94e-2)" "prognostic unfavorable (1.94e-5)" "unprognostic (3.12e-3)" "unprognostic (1.88e-1)" "unprognostic (3.02e-8)" "unprognostic (1.11e-2)" "unprognostic (6.97e-2)" "unprognostic (3.52e-2)" "unprognostic (6.34e-2)" "unprognostic (7.70e-3)" "unprognostic (4.18e-6)" "unprognostic (2.65e-2)" "unprognostic (1.50e-1)" "unprognostic (1.14e-3)" "unprognostic (6.20e-2)" 2.5 6.8 55.0 2.5 70.6 11.9 2.4 28.8 128.5 5.3 13.3 10.8 4.4 3.9 1.5 1.8 3.8 6.8 1.7 76.1 24.5 3.4 2.3 3.4 1.0 16.8 20.1 3.1 10.8 0.9 98.5 2.3 17.8 4.6 2.0 2.5 3.0 1.4 2.1 1.8 4.3 2.7 15.8 2.5 7.8 4.6 23.3 1.2 2.7 0.7 0.6 4.1 4.1 55.3 4.6 21.9 3.4 10.1 4.4 11.7 2.3 14.3 9.5 5.9 3.9 7.4 12.2 5.8 2.1 10.3 32.2 3.7 5.0 9.2 4.4 10.2 3.9 1.8 8.7 4.4 4.9 2.7 5.2 6.8 3.8 41.4 14.4 26.7 10.4 0.9 4.9 6.5 11.4 10.8 1.7 21.1 2.7 8.1 47.8 0.0 2.4 5.7 4.9 3.9 139.9 22.5 4.3 12.1 3.0 4.0 3.9 1.8 39.7 28.9 9.6 22.4 39.0 3.7 2.5 2.7 92.2 2.2 34.5 0.0 0.0 0.0 0.6 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.7 55.0 70.6 28.8 128.5 76.1 24.5 16.8 20.1 17.8 15.8 23.3 55.3 0.9 0.0 2.8 8.1 0.4 4.2 10.7 6.2 0.6 6.2 4.6 3.4 3.2 4.3 5.9 1.8 4.2 0.4 5.0 1.3 0.0 4.0 0.1 4.5 2.9 1.6 52.7 0.4 60.6 3.6 1.9 2.2 3.1 11.1 15.2 2.2 1.8 0.2 0.7 8.4 16.6 2.8 8.2 1.2 2.1 0.2 1.8 6.1 3.6 5.6 0.1 1.0 6.2 8.5 4.8 29.8 1.2 1.5 1.0 10.5 3.4 0.5 7.4 1.9 0.0 1.9 2.8 1.6 3.8 0.6 2.7 0.7 5.3 1.7 1.5 18.9 STX1B "STX1B1, STX1B2" ENSG00000099365 "Syntaxin 1B" P61266 16 30989256-31010638 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter transport, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "brain: 137.2" "Cell type enhanced" "Detected in some" "Excitatory neurons: 36.8;Horizontal cells: 38.7;Inhibitory neurons: 31.1;Late spermatids: 13.8" "Cancer enriched" "Detected in some" 7 "glioma: 5.1" "Region enhanced" "Detected in many" "cerebral cortex: 137.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 9.0;hTEC/SVTERT24-B: 11.1;hTERT-RPE1: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069176, CAB079008" Supported Approved Approved "Nuclear membrane,Vesicles" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 62: Horizontal cells - Visual perception" Vesicles "Nuclear membrane" "CAB079008: , HPA069176: AB_2686098" "unprognostic (1.43e-3)" "unprognostic (5.27e-2)" "unprognostic (2.40e-4)" "unprognostic (3.90e-3)" "unprognostic (3.98e-2)" "unprognostic (1.90e-2)" "unprognostic (2.21e-3)" "unprognostic (2.53e-2)" "unprognostic (1.72e-1)" "unprognostic (3.72e-3)" "unprognostic (1.73e-2)" "unprognostic (2.36e-1)" "unprognostic (1.02e-3)" "unprognostic (1.07e-1)" "unprognostic (1.58e-1)" "unprognostic (7.93e-2)" "unprognostic (1.57e-2)" 1.5 1.0 7.0 1.1 13.1 0.4 1.7 20.0 137.2 1.7 0.0 2.5 0.5 3.0 3.3 1.2 1.7 0.3 1.6 15.9 5.2 1.3 5.9 0.5 1.7 51.2 5.5 1.7 0.9 0.2 6.5 0.2 42.9 1.7 0.4 10.2 1.0 1.8 0.5 3.3 1.8 1.6 0.0 1.8 0.9 4.6 5.8 0.5 0.7 0.1 1.5 0.7 1.3 52.8 0.1 3.0 4.7 0.7 0.5 0.2 0.1 4.2 6.4 5.1 9.0 0.0 3.4 0.7 0.2 5.6 0.1 0.7 2.1 0.6 6.1 2.6 0.4 0.4 2.7 2.4 0.4 0.2 2.9 1.6 0.1 11.1 1.0 20.4 0.0 1.0 0.5 0.2 5.5 1.3 2.0 0.2 2.3 0.0 0.3 7.1 0.2 0.2 0.4 0.0 6.3 4.0 0.5 0.2 0.0 0.7 0.8 0.1 0.8 3.0 2.4 0.4 0.2 0.3 0.2 0.3 3.3 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.0 13.1 20.0 137.2 15.9 5.2 51.2 5.5 42.9 0.0 5.8 52.8 0.4 0.0 0.0 7.2 0.6 0.8 0.1 0.2 0.6 10.7 0.4 0.6 1.2 0.0 0.0 0.0 2.1 0.0 0.2 0.1 0.0 0.3 6.9 0.1 0.5 0.8 0.0 0.4 36.8 0.4 0.0 0.7 0.0 0.1 0.0 2.5 1.1 5.9 0.6 38.7 31.1 0.2 0.0 0.6 1.1 13.8 0.3 0.3 0.0 4.7 0.7 1.8 0.0 9.0 5.5 0.2 0.0 1.9 0.0 0.2 0.9 2.1 0.0 3.2 0.0 0.8 0.7 4.6 1.3 0.2 0.6 0.8 0.4 0.1 0.3 0.0 STX2 "EPIM, EPM, STX2A, STX2B, STX2C" ENSG00000111450 "Syntaxin 2" P32856 12 130789600-130839266 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 152.2;Endometrial ciliated cells: 86.4;Late spermatids: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069176, CAB079007" Uncertain Supported Approved "Nuclear membrane,Vesicles" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" Vesicles "Nuclear membrane" "CAB079007: , HPA069176: AB_2686098" "unprognostic (1.56e-2)" "unprognostic (3.43e-2)" "unprognostic (8.29e-2)" "unprognostic (2.22e-1)" "unprognostic (3.38e-2)" "unprognostic (9.85e-2)" "unprognostic (2.11e-2)" "unprognostic (4.16e-2)" "unprognostic (2.83e-1)" "unprognostic (7.62e-2)" "unprognostic (1.30e-2)" "unprognostic (5.69e-2)" "prognostic unfavorable (5.15e-5)" "unprognostic (3.81e-2)" "unprognostic (2.19e-1)" "unprognostic (1.63e-2)" "unprognostic (3.41e-3)" 17.7 11.0 11.2 9.1 11.7 6.4 12.0 12.3 13.4 15.1 24.7 21.2 4.2 14.3 9.8 6.0 16.3 9.9 17.0 12.2 12.1 14.4 13.3 17.8 8.6 15.5 12.3 15.3 10.9 5.9 14.6 13.2 14.5 8.4 6.8 16.7 5.0 10.6 6.7 5.1 11.4 17.2 13.0 12.4 11.4 17.0 11.8 6.9 12.4 7.9 6.2 14.5 10.7 16.3 9.6 18.3 26.8 22.4 27.8 63.2 2.8 44.2 35.8 50.8 35.7 5.5 6.6 11.7 6.6 50.5 16.4 2.8 24.4 6.6 54.9 18.7 9.2 6.4 15.9 15.7 30.6 9.2 15.5 23.4 8.3 24.9 20.1 48.2 27.6 12.7 25.7 11.2 46.2 5.6 13.3 10.6 17.9 2.9 28.2 13.7 18.9 7.0 28.7 2.1 24.3 25.4 20.4 1.8 18.1 23.4 6.1 6.4 36.5 30.1 20.3 33.1 19.6 8.1 6.7 7.9 35.0 10.8 24.4 1.0 0.4 0.6 0.5 0.5 0.5 0.5 0.6 0.5 0.3 0.3 0.6 0.6 0.4 0.2 0.2 0.3 0.4 0.2 11.2 11.7 12.3 13.4 12.2 12.1 15.5 12.3 14.5 13.0 11.8 16.3 35.3 22.4 14.8 20.5 6.2 3.4 1.2 2.1 3.4 5.6 2.1 3.0 17.2 11.5 6.9 29.5 0.0 1.8 12.3 0.4 9.8 19.1 152.2 86.4 40.0 22.4 6.7 32.4 33.6 7.4 7.1 26.5 2.6 7.6 1.3 10.9 17.9 19.0 11.5 0.0 17.6 0.7 2.0 11.5 12.3 114.4 28.0 15.1 14.2 23.4 10.3 12.3 6.2 15.1 24.3 14.5 0.1 24.5 10.2 2.0 0.1 17.6 33.9 31.4 13.1 26.1 29.6 42.0 34.2 1.7 1.4 0.8 14.2 11.7 0.6 0.5 STX3 STX3A ENSG00000166900 "Syntaxin 3" Q13277 11 59713456-59805882 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "retina: 313.2" "Cell type enhanced" "Detected in all" "Bipolar cells: 373.0;Cone photoreceptor cells: 394.0;Rod photoreceptor cells: 400.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 42.5;eosinophil: 74.1;neutrophil: 60.7" "Lineage enriched" "Detected in many" 10 "granulocytes: 74.1" "Cell line enhanced" "Detected in many" "SK-MEL-30: 167.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002191, HPA069176" Approved Approved "Nuclear membrane,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 3: HMC-1 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "Nuclear membrane" "HPA002191: AB_1080165, HPA069176: AB_2686098" "unprognostic (2.24e-2)" "unprognostic (1.97e-2)" "unprognostic (7.96e-3)" "unprognostic (1.02e-1)" "unprognostic (2.84e-2)" "unprognostic (2.36e-3)" "prognostic unfavorable (8.41e-7)" "unprognostic (1.64e-1)" "unprognostic (3.00e-1)" "unprognostic (7.71e-3)" "unprognostic (2.07e-2)" "unprognostic (5.55e-2)" "prognostic favorable (1.14e-6)" "unprognostic (1.06e-1)" "unprognostic (2.85e-1)" "unprognostic (4.02e-2)" "unprognostic (1.17e-2)" 16.4 24.1 10.1 23.7 11.8 59.2 20.1 18.3 14.6 21.1 11.8 51.0 59.5 29.7 36.7 21.4 15.1 39.1 16.4 10.8 11.2 58.6 15.4 40.7 9.7 11.7 11.9 18.7 24.0 34.1 19.4 50.3 13.4 20.2 56.3 313.2 21.6 24.6 10.9 26.2 44.1 26.4 9.7 23.4 47.5 22.1 12.4 7.4 27.8 17.9 13.8 28.3 18.3 13.1 40.1 23.8 0.9 11.0 20.5 11.5 33.1 21.1 37.7 49.4 61.0 109.4 38.2 11.2 38.9 16.1 85.6 44.0 63.5 22.0 59.4 9.6 12.0 12.7 16.4 34.0 51.1 41.7 116.4 21.0 46.6 38.3 46.2 30.5 39.7 16.6 110.5 23.0 21.5 23.8 0.4 28.9 60.1 63.1 18.2 14.5 40.8 18.6 92.7 94.5 27.0 41.4 9.0 48.0 167.2 79.9 52.1 29.0 54.0 20.8 44.0 28.6 19.3 25.8 49.4 22.8 27.8 27.0 29.0 42.5 6.3 74.1 2.4 1.9 2.5 1.0 3.3 1.6 7.1 3.1 3.0 0.9 60.7 0.5 1.2 1.0 0.0 2.7 10.1 11.8 18.3 14.6 10.8 11.2 11.7 11.9 13.4 9.7 12.4 13.1 17.0 67.3 30.6 2.6 9.5 50.7 69.5 12.8 30.1 373.0 43.5 15.2 10.2 31.5 18.9 11.0 394.0 10.1 5.9 124.6 17.6 40.2 4.8 37.8 9.6 30.2 26.3 4.4 40.4 25.6 15.9 12.8 29.6 68.5 58.2 14.9 20.7 5.6 16.0 72.3 33.0 36.5 18.3 18.9 49.7 7.5 3.7 26.4 37.4 24.4 28.7 48.4 11.3 3.5 25.3 48.9 64.1 7.5 5.8 87.2 34.0 69.5 13.3 400.3 6.6 10.0 15.9 4.6 20.6 29.4 60.1 40.5 17.9 5.6 26.5 87.7 STX8 CARB ENSG00000170310 "Syntaxin 8" Q9UNK0 17 9250471-9576591 "Predicted intracellular proteins, Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 261.6;Late spermatids: 964.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001540 Approved Approved Vesicles,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 31: Spermatids - Spermatogenesis" Vesicles Cytosol "HPA001540: AB_1080168" "unprognostic (8.68e-2)" "unprognostic (2.29e-2)" "unprognostic (2.53e-1)" "unprognostic (4.14e-3)" "unprognostic (3.36e-1)" "unprognostic (1.58e-2)" "unprognostic (6.91e-2)" "unprognostic (1.19e-1)" "unprognostic (3.12e-1)" "unprognostic (4.91e-2)" "unprognostic (1.86e-3)" "unprognostic (2.54e-1)" "unprognostic (1.45e-2)" "unprognostic (2.89e-2)" "unprognostic (1.89e-1)" "unprognostic (1.77e-2)" "unprognostic (1.51e-1)" 50.7 42.9 51.1 21.7 51.9 42.9 45.6 52.3 72.9 46.8 53.0 59.5 23.1 41.5 64.2 35.6 38.8 28.5 56.2 51.6 51.4 46.3 48.0 35.4 32.8 52.4 51.9 42.6 45.2 42.8 33.7 29.1 53.1 40.2 38.7 32.3 42.8 41.0 64.0 39.7 34.1 42.4 52.7 35.7 43.3 76.2 51.6 43.5 42.8 61.5 39.4 48.6 41.9 54.5 35.1 65.9 54.6 28.9 86.2 107.7 24.6 40.3 69.4 55.6 73.5 22.5 27.6 42.3 34.6 79.7 48.0 37.7 35.5 76.6 86.2 66.6 59.2 26.7 19.0 52.5 117.4 20.3 47.1 87.9 120.9 43.8 65.7 66.5 67.2 44.8 13.2 18.8 62.5 18.5 39.9 41.6 14.2 41.5 34.2 56.2 46.6 25.9 71.8 32.6 7.3 34.7 30.8 16.3 48.2 73.8 21.3 32.3 61.0 42.8 26.6 24.5 54.3 17.5 17.3 16.3 64.1 47.4 39.6 117.0 142.5 159.3 124.3 128.0 113.5 117.0 133.3 139.5 142.6 108.8 85.6 100.7 40.9 167.4 132.6 123.1 198.8 197.8 51.1 51.9 52.3 72.9 51.6 51.4 52.4 51.9 53.1 52.7 51.6 54.5 39.2 32.1 27.0 65.3 37.0 45.8 52.8 83.8 23.3 15.2 32.8 36.2 61.5 31.5 58.5 29.5 12.5 55.9 49.8 34.6 103.7 62.3 261.6 31.4 33.2 33.9 25.0 25.2 79.7 82.8 55.3 49.3 23.0 27.7 54.5 33.5 29.3 38.6 87.1 6.7 63.0 41.2 85.5 46.3 84.0 964.1 46.3 43.6 78.2 89.9 70.4 58.4 107.1 91.0 86.9 69.9 58.1 47.4 23.5 23.8 66.2 93.5 45.0 24.3 13.1 33.9 59.7 58.6 23.8 29.4 44.6 43.4 54.2 20.1 31.2 38.7 SULT2B1 HSST2 ENSG00000088002 "Sulfotransferase family 2B member 1" O00204 19 48552172-48599425 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 286.0;skin 1: 186.5;vagina: 145.9" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 62.3;Proximal enterocytes: 75.9;Squamous epithelial cells: 56.0;Suprabasal keratinocytes: 137.4;Urothelial cells: 114.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CAPAN-2: 74.2;MCF7: 46.8;OE19: 122.9;T-47d: 36.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041724, HPA043539, HPA076510" Enhanced Enhanced Vesicles,Cytosol NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" Vesicles Cytosol "HPA041724: AB_2677638, HPA043539: AB_2678540, HPA076510: " "unprognostic (6.55e-2)" "unprognostic (1.47e-1)" "unprognostic (5.28e-3)" "unprognostic (8.74e-2)" "unprognostic (5.00e-2)" "unprognostic (5.97e-2)" "unprognostic (4.43e-2)" "unprognostic (3.29e-3)" "unprognostic (1.62e-1)" "unprognostic (1.11e-2)" "unprognostic (2.54e-2)" "unprognostic (4.42e-2)" "unprognostic (5.01e-6)" "unprognostic (7.96e-3)" "unprognostic (1.32e-1)" "unprognostic (8.04e-2)" "unprognostic (2.77e-2)" 0.3 0.2 0.5 0.4 0.4 0.1 11.5 0.6 0.8 74.4 0.4 0.8 9.3 0.5 6.8 286.0 1.2 2.7 0.2 0.5 0.5 13.0 0.3 9.4 0.0 0.5 0.7 0.1 0.7 7.9 0.4 1.5 0.5 22.6 0.2 0.0 53.6 3.7 0.4 186.5 18.2 0.1 0.4 0.1 3.5 0.5 0.9 0.4 1.9 0.0 28.3 0.7 145.9 0.5 12.6 15.8 0.0 0.3 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.9 74.2 0.1 0.1 0.0 0.7 3.9 0.1 0.3 0.0 0.5 0.4 0.0 0.5 0.5 0.0 0.0 7.2 0.2 2.1 0.0 0.0 0.1 0.0 0.8 0.1 0.1 0.0 46.8 0.0 0.5 0.0 122.9 0.0 0.1 0.0 0.1 0.0 3.5 0.2 0.1 0.0 6.2 0.3 0.0 36.7 0.1 0.2 0.0 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.4 0.3 0.5 0.1 0.0 0.3 0.2 0.6 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.2 0.1 0.2 0.5 0.4 0.6 0.8 0.5 0.5 0.5 0.7 0.5 0.4 0.9 0.5 0.4 19.2 0.5 1.0 0.0 24.1 30.5 11.6 0.0 0.0 16.8 12.4 0.6 5.7 40.2 9.2 0.0 3.2 0.0 4.4 0.0 12.2 0.0 15.7 1.4 0.9 4.8 0.0 1.0 1.2 3.1 1.2 2.6 17.5 0.0 0.1 0.0 0.3 0.7 0.0 0.9 12.6 24.4 0.0 4.8 0.9 0.3 0.4 12.4 1.0 0.0 1.6 0.0 0.5 0.8 18.5 7.9 0.0 0.0 62.3 75.9 1.3 6.7 0.6 0.0 0.1 2.2 0.2 11.1 56.0 137.4 1.9 0.6 2.0 9.2 114.6 SUMF2 DKFZp566I1024 ENSG00000129103 "Sulfatase modifying factor 2" Q8NBJ7 7 56064002-56080670 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA024040, CAB025743, HPA074892" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" Yes No 750000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "CAB025743: , HPA024040: AB_1857651, HPA074892: " "unprognostic (2.93e-1)" "prognostic unfavorable (6.58e-6)" "unprognostic (2.42e-2)" "prognostic favorable (3.96e-4)" "unprognostic (3.87e-2)" "unprognostic (9.11e-3)" "unprognostic (1.69e-2)" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (7.20e-2)" "unprognostic (1.92e-1)" "unprognostic (7.26e-2)" "unprognostic (1.74e-1)" "unprognostic (1.74e-2)" "unprognostic (2.64e-1)" "unprognostic (1.99e-3)" "prognostic unfavorable (7.71e-4)" 64.1 64.6 26.1 43.0 29.7 51.5 57.5 29.3 27.1 91.3 45.0 67.4 89.2 57.5 64.8 46.8 102.6 70.6 30.8 25.1 27.8 93.4 94.8 71.6 50.2 35.2 29.6 59.7 91.8 115.8 31.8 45.5 33.4 79.3 69.1 11.0 69.5 77.1 22.4 47.5 74.4 57.7 29.9 57.0 92.7 23.7 30.8 57.6 91.2 21.4 51.3 57.2 43.6 35.9 352.3 102.9 46.0 211.8 214.4 147.5 68.9 114.5 156.1 92.6 114.5 57.2 278.0 57.1 96.5 162.4 90.4 172.3 27.4 131.3 61.1 90.6 42.9 36.4 63.5 54.2 138.4 89.7 108.7 116.8 124.5 83.7 143.3 186.9 137.7 101.4 116.4 236.6 151.3 76.8 77.2 115.7 63.5 272.0 52.2 61.5 45.4 359.0 127.7 39.1 54.0 65.6 142.4 294.2 140.9 98.9 294.5 144.5 115.2 85.6 121.1 211.1 98.6 160.8 130.8 84.0 139.7 165.7 283.2 58.1 60.3 22.0 71.1 80.5 90.9 59.8 70.9 71.8 72.3 49.1 75.3 75.2 4.4 49.0 90.3 132.6 82.7 90.2 26.1 29.7 29.3 27.1 25.1 27.8 35.2 29.6 33.4 29.9 30.8 35.9 44.0 57.7 30.5 20.5 47.3 33.8 44.1 46.1 39.9 25.7 57.9 25.4 10.4 87.2 31.0 90.1 14.6 44.5 85.3 45.1 19.6 95.3 3.8 93.1 70.2 43.7 59.3 41.7 21.2 55.7 96.7 54.7 55.5 78.9 54.5 47.0 51.0 91.3 68.1 43.7 24.4 61.8 22.4 79.8 38.7 8.0 69.6 50.4 53.4 14.0 73.0 23.8 70.0 10.6 24.2 48.4 64.6 47.4 65.0 50.7 91.8 45.6 34.5 13.5 52.6 41.6 44.1 31.6 28.6 52.8 41.9 46.7 52.7 58.7 85.8 42.7 SUSD4 FLJ10052 ENSG00000143502 "Sushi domain containing 4" Q5VX71 1 223220819-223364233 "Predicted intracellular proteins, Predicted membrane proteins" "Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 69.0;esophagus: 51.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 83.7;Inhibitory neurons: 89.7;Oligodendrocyte precursor cells: 101.6;Squamous epithelial cells: 68.3;Theca cells: 65.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 6.8;naive CD4 T-cell: 10.2" "Lineage enriched" "Detected in single" 40 "T-cells: 10.2" "Cell line enhanced" "Detected in some" "HaCaT: 9.7;RPTEC TERT1: 11.1;SCLC-21H: 36.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058296 Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA058296: AB_2683672" "unprognostic (2.90e-1)" "unprognostic (2.90e-3)" "unprognostic (1.27e-3)" "prognostic unfavorable (4.28e-4)" "unprognostic (2.12e-1)" "unprognostic (7.01e-2)" "unprognostic (7.53e-3)" "unprognostic (1.82e-3)" "unprognostic (7.94e-2)" "unprognostic (1.57e-1)" "unprognostic (1.27e-3)" "unprognostic (1.36e-1)" "unprognostic (6.51e-6)" "unprognostic (3.64e-2)" "unprognostic (5.11e-2)" "unprognostic (3.03e-1)" "unprognostic (7.11e-2)" 0.4 6.0 28.4 0.8 21.7 0.4 8.7 5.4 63.7 9.5 0.0 1.3 1.0 0.3 25.1 51.1 3.5 0.7 23.0 69.0 26.8 19.5 3.8 2.8 1.6 9.4 10.4 45.3 10.7 14.9 26.0 0.5 15.9 6.0 0.2 12.2 17.0 4.3 3.5 7.8 0.6 0.4 5.0 0.4 11.0 6.6 21.4 3.4 1.0 2.2 15.0 3.6 25.3 16.2 5.9 0.5 0.2 0.0 0.0 0.0 0.1 0.8 0.4 1.0 0.5 5.8 1.8 0.0 1.8 0.2 0.0 9.7 0.2 1.5 0.9 0.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.6 0.2 0.0 6.6 0.5 0.0 0.5 3.9 3.8 0.0 0.2 3.0 1.3 0.0 0.2 0.1 11.1 2.8 36.3 0.4 0.0 3.2 0.0 0.8 2.1 0.2 0.0 1.7 6.2 0.0 2.9 0.7 0.1 0.0 0.1 0.1 0.8 0.0 0.1 0.0 0.3 0.1 5.5 0.0 6.8 1.7 0.0 0.0 10.2 1.9 0.0 0.2 0.0 0.0 0.9 1.4 28.4 21.7 5.4 63.7 69.0 26.8 9.4 10.4 15.9 5.0 21.4 16.2 0.2 0.0 4.8 6.2 0.0 0.6 8.6 8.4 10.2 17.9 9.7 5.0 9.5 5.7 14.8 16.5 10.4 0.1 0.3 0.1 31.3 0.6 3.1 4.0 0.4 0.6 1.2 0.0 83.7 6.9 0.0 3.8 2.6 6.1 0.0 9.1 0.4 1.8 2.8 21.9 89.7 0.1 2.0 0.6 0.3 3.4 20.5 0.3 5.4 8.4 0.0 1.6 0.0 101.6 2.5 2.6 0.0 12.4 0.1 4.6 0.0 0.3 5.4 6.2 0.0 1.4 2.8 1.3 10.7 68.3 1.7 0.0 1.7 65.5 0.3 25.7 SUSD5 KIAA0527 ENSG00000173705 "Sushi domain containing 5" O60279 3 33150043-33218810 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Excitatory neurons: 15.4;Inhibitory neurons: 10.5;Oligodendrocyte precursor cells: 61.3;Sertoli cells: 32.9;Smooth muscle cells: 29.0" "Cancer enhanced" "Detected in many" "melanoma: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 31.1;HUVEC TERT2: 78.5;LHCN-M2: 30.4;TIME: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052788 Uncertain Uncertain "Golgi apparatus,Vesicles" NA NA 17000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus, Vesicles" "HPA052788: AB_2681948" "unprognostic (1.81e-1)" "unprognostic (1.52e-2)" "unprognostic (5.84e-3)" "unprognostic (5.52e-3)" "unprognostic (1.39e-3)" "unprognostic (4.05e-2)" "unprognostic (3.72e-1)" "unprognostic (6.28e-2)" "unprognostic (2.77e-1)" "unprognostic (2.24e-2)" "unprognostic (1.69e-1)" "unprognostic (2.15e-1)" "unprognostic (6.00e-3)" "unprognostic (1.10e-3)" "unprognostic (6.45e-2)" "unprognostic (8.46e-2)" "unprognostic (1.89e-2)" 4.6 1.4 2.9 0.9 3.0 0.1 1.9 2.2 4.6 6.3 4.4 1.7 0.8 4.6 2.2 1.3 5.2 5.5 1.5 3.1 4.4 1.5 0.5 1.7 2.3 3.4 3.4 3.8 0.6 1.0 0.8 0.2 3.4 1.3 1.2 0.6 0.7 6.3 1.6 1.9 1.9 4.8 3.8 2.5 1.8 2.1 4.7 0.1 3.2 3.3 5.3 1.5 2.4 3.5 0.0 1.1 1.2 0.7 1.7 0.2 0.1 9.6 3.4 31.1 10.5 0.1 0.0 0.0 8.8 2.5 9.5 0.1 13.7 4.5 12.9 0.3 15.3 0.0 2.0 0.0 0.2 0.1 0.1 1.3 2.4 19.9 3.9 15.2 78.5 0.0 0.0 0.1 30.4 0.0 0.0 0.1 1.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 2.0 1.0 0.1 0.1 2.5 0.7 1.8 1.9 31.3 0.0 14.4 1.2 4.7 0.0 0.7 0.0 0.3 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.9 3.0 2.2 4.6 3.1 4.4 3.4 3.4 3.4 3.8 4.7 3.5 0.1 0.0 0.0 0.3 0.0 1.0 0.1 0.0 0.0 1.9 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 2.2 0.5 0.0 0.0 15.4 0.0 0.1 1.4 0.0 0.9 0.0 0.2 0.4 0.0 0.0 3.3 10.5 0.0 0.0 2.1 2.0 0.3 0.0 0.1 1.8 0.0 0.0 0.5 0.0 61.3 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.7 32.9 3.6 29.0 0.1 2.6 0.1 1.0 0.0 0.2 0.1 0.0 0.1 SV2C ENSG00000122012 "Synaptic vesicle glycoprotein 2C" Q496J9 5 76083383-76353939 "Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "brain: 55.7" "Group enriched" "Detected in some" 4 "Excitatory neurons: 85.0;Inhibitory neurons: 82.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 15 "basophil: 1.5" "Lineage enriched" "Detected in single" 15 "granulocytes: 1.5" "Group enriched" "Detected in some" 5 "Karpas-707: 9.1;SCLC-21H: 3.7;SH-SY5Y: 8.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040722, HPA040770" Supported Supported Nucleoplasm,Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Vesicles" "HPA040722: AB_10795624, HPA040770: AB_10805828" "unprognostic (7.91e-2)" "unprognostic (2.33e-1)" "unprognostic (2.05e-1)" "unprognostic (2.41e-2)" "unprognostic (1.07e-1)" "unprognostic (9.93e-2)" "unprognostic (1.09e-2)" "unprognostic (2.57e-1)" "unprognostic (2.57e-1)" "unprognostic (2.14e-1)" "unprognostic (1.44e-1)" "unprognostic (2.34e-2)" "unprognostic (1.60e-3)" "unprognostic (1.90e-1)" "unprognostic (2.12e-1)" "unprognostic (6.66e-2)" "unprognostic (1.16e-1)" 0.0 1.2 4.7 0.2 31.4 0.1 0.2 11.1 32.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.0 0.1 0.0 55.7 0.0 0.0 0.0 0.0 26.1 39.5 0.5 0.1 0.0 0.4 0.0 42.2 0.1 0.1 4.3 0.3 0.2 0.0 0.0 0.2 0.2 9.1 0.0 0.5 0.1 20.2 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 9.1 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.7 8.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 31.4 11.1 32.0 0.0 55.7 26.1 39.5 42.2 9.1 20.2 10.2 0.5 0.0 0.0 5.5 0.1 0.0 0.7 0.4 0.0 5.4 0.7 0.1 0.8 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.6 2.5 0.6 0.4 19.8 0.0 85.0 0.2 0.0 0.1 0.0 2.1 0.0 0.5 0.7 0.0 0.1 0.0 82.6 0.6 2.0 0.6 0.3 0.8 0.0 0.2 3.6 2.8 0.0 1.0 0.0 3.0 3.1 0.0 0.2 0.0 0.3 0.6 0.0 0.0 0.1 5.6 0.0 0.2 0.4 0.2 0.7 0.0 0.1 0.0 0.2 0.8 0.2 1.5 SYBU "FLJ20366, GOLSYN, KIAA1472, OCSYN, SNPHL" ENSG00000147642 Syntabulin Q9NX95 8 109573978-109691791 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 140.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 200.5;Horizontal cells: 95.9;Inhibitory neurons: 129.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 21 "memory B-cell: 6.4;naive B-cell: 3.2" "Lineage enriched" "Detected in single" 27 "B-cells: 6.4" "Cell line enhanced" "Detected in many" "HaCaT: 24.4;PC-3: 25.7;SK-BR-3: 51.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053057 Uncertain Supported Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA053057: AB_2682028" "unprognostic (4.69e-2)" "unprognostic (1.40e-1)" "unprognostic (2.46e-1)" "unprognostic (1.31e-1)" "unprognostic (1.18e-1)" "unprognostic (4.27e-1)" "prognostic favorable (7.74e-4)" "unprognostic (1.22e-2)" "unprognostic (1.37e-1)" "unprognostic (2.16e-1)" "unprognostic (3.13e-1)" "unprognostic (5.52e-2)" "unprognostic (1.87e-3)" "unprognostic (1.68e-1)" "unprognostic (6.05e-3)" "unprognostic (6.89e-2)" "unprognostic (4.27e-2)" 32.2 38.7 39.1 3.2 42.0 0.0 22.2 44.5 52.4 10.7 4.4 15.4 10.9 5.6 11.5 5.6 20.1 10.3 6.9 42.4 58.6 4.2 52.1 8.8 4.4 24.2 34.0 9.2 140.5 1.5 30.4 2.5 36.6 8.2 19.7 26.1 21.5 11.0 3.8 9.6 12.0 6.9 22.8 1.0 28.2 1.8 50.8 5.4 12.3 7.7 7.8 5.9 8.8 30.2 8.6 5.2 3.6 0.0 0.5 0.6 2.5 3.1 0.0 0.0 0.0 7.9 5.4 0.7 0.5 2.5 1.2 24.4 0.8 5.7 0.0 0.1 11.6 0.0 15.2 8.2 6.2 0.0 0.0 1.9 7.7 0.0 7.2 0.4 3.3 0.6 0.4 1.6 3.5 0.2 0.2 0.0 0.7 7.7 25.7 0.0 0.0 0.0 9.5 2.2 16.3 1.9 6.9 51.4 1.7 2.5 6.8 0.3 5.0 0.3 2.0 0.1 1.5 1.5 0.1 0.5 10.8 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.1 6.4 0.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 39.1 42.0 44.5 52.4 42.4 58.6 24.2 34.0 36.6 22.8 50.8 30.2 39.3 9.6 7.7 16.0 4.3 5.7 2.5 8.3 17.1 46.1 10.9 9.1 2.4 30.0 18.0 11.0 8.4 4.6 0.1 3.6 3.9 5.4 1.4 29.3 3.4 11.8 34.5 0.0 200.5 9.4 0.9 7.9 5.6 20.9 0.0 0.7 10.0 39.1 0.3 95.9 129.6 22.2 2.0 0.8 4.2 0.4 2.1 0.3 1.8 21.5 0.7 2.1 0.0 22.1 5.7 3.9 9.8 0.4 0.1 11.8 16.2 0.1 15.6 7.4 0.0 16.5 4.2 1.3 1.5 3.5 3.3 0.7 0.6 0.1 13.7 4.2 SYCE1 "bA108K14.6, C10orf94, CT76" ENSG00000171772 "Synaptonemal complex central element protein 1" Q8N0S2 10 133553901-133569835 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" "Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 70.9" "Group enriched" "Detected in many" 6 "Early spermatids: 141.2;Late spermatids: 112.6;Spermatocytes: 362.8;Spermatogonia: 170.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "K-562: 18.5;U-2 OS: 15.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040208 Enhanced Approved Nucleoplasm,Vesicles,Cytosol No No "Cluster 39: Non-specific - mRNA processing" "Cluster 78: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Vesicles, Cytosol" "HPA040208: AB_10796450" "unprognostic (5.04e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-2)" "unprognostic (1.85e-1)" "unprognostic (9.05e-2)" "unprognostic (1.61e-1)" "unprognostic (3.20e-1)" "unprognostic (5.75e-1)" "unprognostic (5.38e-2)" "unprognostic (3.36e-1)" "unprognostic (2.22e-2)" "unprognostic (7.17e-3)" "unprognostic (2.95e-2)" "unprognostic (1.27e-1)" "unprognostic (1.69e-1)" "unprognostic (2.42e-1)" 1.9 1.6 8.5 0.6 8.5 0.0 1.4 9.1 11.6 1.3 2.0 0.9 0.1 0.9 0.3 0.7 1.2 1.2 0.7 9.0 6.3 1.2 4.0 0.4 0.2 6.6 5.4 2.0 3.8 0.0 1.2 9.4 6.4 1.7 0.4 2.3 0.2 0.4 0.9 0.5 0.5 0.6 3.7 0.9 0.6 70.9 6.7 0.2 1.4 1.7 0.5 0.4 0.4 8.1 0.1 0.0 0.0 0.1 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.8 0.0 0.5 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.5 0.0 0.0 0.1 0.1 0.5 0.3 0.0 0.3 1.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.2 0.1 0.1 0.1 15.5 0.2 0.4 0.2 0.3 0.4 0.0 0.1 0.0 0.0 0.5 0.1 0.9 0.6 0.8 0.2 0.6 0.2 0.3 0.3 0.3 0.8 0.0 0.0 0.8 0.6 0.7 0.4 8.5 8.5 9.1 11.6 9.0 6.3 6.6 5.4 6.4 3.7 6.7 8.1 0.7 0.0 1.5 0.7 0.3 1.0 1.2 0.0 0.0 2.7 1.0 2.4 0.3 1.5 1.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 141.2 1.2 3.2 1.3 0.0 0.0 29.8 1.1 0.2 5.6 0.5 0.6 0.0 0.0 0.0 7.8 0.7 10.1 19.1 0.0 0.0 0.3 0.9 112.6 5.3 0.9 0.0 0.0 0.0 0.3 0.0 7.1 0.8 0.4 0.3 3.8 0.1 0.6 0.0 0.5 1.5 2.1 26.3 0.5 0.9 362.8 170.9 0.0 1.0 0.3 0.5 7.0 0.0 0.6 SYK ENSG00000165025 "Spleen associated tyrosine kinase" P43405 9 90801787-90898549 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Host-virus interaction, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 73.8;parathyroid gland: 87.6" "Cell type enhanced" "Detected in many" "B-cells: 91.3;Hofbauer cells: 73.1;Kupffer cells: 96.7;Macrophages: 95.2;Microglial cells: 114.3;monocytes: 92.5;Plasma cells: 83.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "classical monocyte: 77.3;eosinophil: 83.5;intermediate monocyte: 64.0;memory B-cell: 74.5;myeloid DC: 85.1;naive B-cell: 58.4;neutrophil: 112.1;NK-cell: 30.0;non-classical monocyte: 60.2;plasmacytoid DC: 63.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 125.8;HEL: 72.8;HL-60: 101.6;HMC-1: 64.1;REH: 84.4;THP-1: 76.8;U-698: 58.8;U-937: 70.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001384, CAB007773" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" No NA 290000 "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" Vesicles "CAB007773: AB_562232, HPA001384: AB_1080144" "unprognostic (1.01e-1)" "unprognostic (5.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.69e-2)" "unprognostic (2.31e-1)" "unprognostic (7.92e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (6.41e-2)" "unprognostic (1.78e-2)" "unprognostic (7.20e-2)" "unprognostic (9.93e-2)" "unprognostic (2.55e-3)" "unprognostic (8.77e-2)" "unprognostic (5.36e-3)" "unprognostic (3.41e-2)" "unprognostic (1.06e-2)" 7.4 4.6 4.1 42.5 4.1 50.9 6.8 4.5 4.9 7.7 4.2 20.1 30.8 4.1 16.1 17.5 17.0 12.9 2.9 3.8 5.0 11.2 4.5 20.6 61.8 7.1 5.8 1.7 9.1 87.6 2.4 12.0 7.0 3.8 20.5 0.7 8.4 4.2 1.0 9.9 36.3 9.3 6.6 40.3 19.1 6.9 7.1 49.7 25.6 2.4 73.8 17.5 8.3 9.8 22.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 14.3 125.8 3.5 0.0 4.2 19.1 2.7 10.2 0.0 0.0 17.0 72.8 0.0 0.0 0.0 101.6 64.1 0.0 14.0 0.0 1.4 0.0 0.0 15.5 2.0 9.9 0.0 15.4 0.1 44.4 0.7 47.0 0.0 84.4 0.1 34.6 2.6 18.6 6.4 5.7 0.1 8.7 0.1 0.3 7.9 76.8 0.2 0.0 0.4 0.1 0.1 0.2 0.0 58.8 0.0 70.3 0.0 5.3 77.3 83.5 0.3 64.0 0.3 74.5 0.2 0.2 85.1 58.4 0.2 0.1 112.1 30.0 60.2 63.2 0.1 44.6 4.1 4.1 4.5 4.9 3.8 5.0 7.1 5.8 7.0 6.6 7.1 9.8 0.5 12.8 20.2 0.0 91.3 3.4 3.7 8.7 12.0 1.4 6.3 2.8 1.6 14.3 12.8 14.7 0.0 1.3 70.4 16.5 15.6 15.0 7.1 10.7 1.0 2.1 10.3 37.9 0.4 12.5 2.6 2.1 22.4 12.6 43.6 0.0 3.3 1.0 73.1 0.0 0.7 24.4 0.0 96.7 28.8 6.2 0.6 95.2 12.4 114.3 92.5 0.0 62.8 1.5 0.5 18.2 25.1 0.0 83.1 2.5 31.4 0.4 10.4 0.2 6.6 0.7 2.3 0.8 0.7 30.4 5.7 1.4 8.3 0.0 31.1 8.0 SYNC "SYNC1, SYNCOILIN" ENSG00000162520 "Syncoilin, intermediate filament protein" Q9H7C4 1 32679906-32703596 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 106.8;smooth muscle: 54.1;tongue: 73.4" "Cell type enhanced" "Detected in many" "Horizontal cells: 74.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 121.0;U-138 MG: 113.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA028311, HPA063549" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA028311: AB_2672554, HPA063549: " "unprognostic (3.99e-1)" "unprognostic (6.04e-3)" "unprognostic (2.02e-2)" "unprognostic (7.60e-3)" "unprognostic (1.99e-2)" "unprognostic (5.07e-2)" "unprognostic (5.05e-2)" "unprognostic (5.44e-3)" "unprognostic (1.71e-1)" "unprognostic (1.79e-2)" "unprognostic (5.04e-2)" "unprognostic (3.71e-1)" "unprognostic (1.32e-4)" "unprognostic (1.56e-2)" "unprognostic (1.33e-1)" "unprognostic (1.45e-1)" "unprognostic (8.15e-4)" 10.5 8.5 6.4 15.6 6.1 0.7 5.4 6.7 6.6 9.7 6.1 11.6 6.5 10.9 4.9 17.9 7.4 9.5 17.3 5.8 7.9 2.4 2.2 10.5 6.4 8.3 8.7 3.7 2.6 4.7 0.7 2.5 7.9 13.1 8.7 0.4 9.6 14.6 106.8 2.5 7.3 54.1 9.0 6.2 9.0 9.7 7.4 1.1 4.5 73.4 1.7 12.3 2.9 8.2 8.7 7.0 11.2 19.3 19.4 30.5 6.6 41.9 81.5 28.7 19.6 1.2 24.8 23.9 13.0 121.0 43.4 5.8 1.0 0.7 16.2 12.4 0.8 26.1 22.6 18.0 16.4 33.0 12.0 46.6 2.9 31.6 1.1 86.1 9.0 17.2 19.6 26.2 24.3 4.2 32.0 8.9 5.9 11.2 9.6 34.5 36.5 12.7 32.6 14.2 18.1 1.7 57.1 17.6 21.7 22.2 16.0 10.4 14.4 113.0 19.4 69.4 18.8 11.4 21.1 30.2 39.0 10.4 98.3 5.9 7.7 6.1 6.1 9.6 8.1 6.9 6.9 6.4 9.7 5.2 6.2 7.0 0.9 9.1 9.5 12.3 7.9 12.0 6.4 6.1 6.7 6.6 5.8 7.9 8.3 8.7 7.9 9.0 7.4 8.2 10.6 9.6 9.8 15.7 15.1 22.0 14.2 14.5 8.0 50.2 20.6 7.0 1.0 20.0 14.1 9.2 39.6 9.4 20.7 8.3 5.9 11.7 11.2 12.9 25.0 13.1 7.3 16.0 12.2 5.4 9.3 17.1 0.5 16.3 22.2 12.4 22.9 19.1 5.4 74.0 13.2 8.4 8.2 17.7 23.2 14.8 41.7 7.3 33.8 7.5 11.4 20.0 34.0 15.1 11.6 7.9 7.9 64.3 5.7 16.0 10.7 10.1 6.0 53.9 19.7 16.6 12.8 32.8 36.0 7.2 22.3 5.1 15.3 9.4 12.6 9.4 SYNCRIP "dJ3J17.2, GRY-RBP, hnRNP-Q, HNRNPQ, HNRPQ1, NSAP1" ENSG00000135316 "Synaptotagmin binding cytoplasmic RNA interacting protein" O60506 6 85607779-85644063 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Translation regulation" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010895, HPA041275, HPA069241" Supported Approved Nucleoplasm,Vesicles,Cytosol NA NA 1300000 "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Vesicles, Cytosol" "CAB010895: AB_261964, HPA041275: AB_2677389, HPA069241: " "unprognostic (1.01e-1)" "unprognostic (3.49e-2)" "unprognostic (1.02e-2)" "unprognostic (1.20e-1)" "unprognostic (1.49e-2)" "unprognostic (6.22e-2)" "prognostic unfavorable (6.28e-5)" "unprognostic (6.84e-2)" "unprognostic (6.48e-2)" "prognostic favorable (5.59e-4)" "unprognostic (1.58e-2)" "unprognostic (1.43e-1)" "unprognostic (4.86e-2)" "unprognostic (1.37e-1)" "unprognostic (2.34e-1)" "unprognostic (1.00e-1)" "unprognostic (4.11e-1)" 60.5 43.2 25.1 80.2 28.0 67.3 55.6 28.1 24.8 51.4 26.0 54.1 48.0 46.1 41.7 75.8 34.0 47.8 45.6 22.8 29.9 53.1 66.7 49.4 88.1 28.9 27.4 36.2 51.9 56.9 19.5 68.5 31.0 44.9 62.7 36.0 41.4 46.5 55.9 43.5 44.0 62.1 27.7 51.3 50.0 38.7 27.6 91.0 87.3 56.0 101.9 81.5 40.8 29.0 209.5 147.5 239.9 157.1 150.8 165.3 162.8 258.6 218.1 244.4 239.9 250.4 132.6 480.0 200.0 262.8 203.1 197.4 331.1 269.0 405.4 175.9 163.9 405.4 152.8 165.2 130.3 497.6 177.7 141.8 179.6 276.4 272.1 138.4 254.9 133.2 451.5 210.0 295.1 243.5 255.2 218.9 231.5 209.4 153.2 364.7 345.5 209.9 236.2 307.1 239.5 184.6 188.5 180.8 128.6 137.2 150.8 360.9 247.4 165.8 142.7 189.8 374.2 138.0 260.5 275.4 165.4 328.7 251.4 1.8 24.7 8.8 30.6 36.2 30.0 21.9 27.1 27.5 37.7 21.2 23.4 27.7 3.0 36.1 41.1 29.0 31.6 24.6 25.1 28.0 28.1 24.8 22.8 29.9 28.9 27.4 31.0 27.7 27.6 29.0 106.9 115.4 119.5 26.4 73.0 148.2 160.9 124.4 83.6 44.5 89.0 82.8 88.9 52.9 126.7 46.0 16.7 101.3 97.2 50.4 54.8 120.7 117.6 105.1 156.2 100.7 56.7 65.6 24.0 99.6 133.3 101.8 79.5 152.1 61.4 81.6 57.5 81.4 96.9 62.2 24.3 78.0 79.3 71.1 67.1 28.7 73.7 92.9 53.4 31.9 90.7 45.1 57.7 32.2 40.9 130.0 45.7 64.3 97.4 133.0 47.7 80.7 84.6 42.2 19.7 158.6 131.8 93.7 65.8 142.4 141.6 118.1 81.6 85.8 106.7 159.8 SYNDIG1 "C20orf39, DSPC2, FLJ14220, IFITMD5, TMEM90B" ENSG00000101463 "Synapse differentiation inducing 1" Q9H7V2 20 24469629-24666616 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.4;heart muscle: 26.9" "Group enriched" "Detected in some" 4 "Excitatory neurons: 157.4;Microglial cells: 472.2;Oligodendrocytes: 214.3" "Cancer enhanced" "Detected in many" "glioma: 10.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 15.4;RH-30: 43.4;RPMI-8226: 43.6;SCLC-21H: 10.0;U-87 MG: 26.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044271, HPA059267" Enhanced Vesicles NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA044271: AB_2732515, HPA059267: AB_2683961" "unprognostic (9.33e-2)" "unprognostic (1.83e-2)" "unprognostic (2.17e-1)" "unprognostic (9.56e-2)" "unprognostic (5.03e-2)" "unprognostic (1.27e-1)" "unprognostic (1.63e-1)" "unprognostic (1.06e-1)" "unprognostic (1.62e-1)" "unprognostic (4.69e-2)" "unprognostic (4.23e-1)" "unprognostic (3.71e-2)" "unprognostic (1.94e-2)" "unprognostic (7.75e-3)" "unprognostic (2.21e-1)" "prognostic unfavorable (6.16e-6)" "unprognostic (1.40e-3)" 1.8 0.9 23.7 1.5 23.2 0.0 0.5 27.6 26.8 3.2 8.6 0.8 1.2 3.2 0.7 0.2 4.2 8.8 26.9 21.1 21.0 4.9 0.0 0.7 2.0 28.4 23.0 0.9 0.7 0.2 0.7 0.2 28.4 3.3 0.9 1.8 0.3 12.3 0.1 0.2 2.1 2.2 27.8 0.7 1.6 0.8 25.3 1.6 4.8 0.1 2.4 1.7 2.0 36.4 0.0 0.3 2.6 0.0 0.8 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 15.4 0.0 0.8 0.0 0.0 2.6 0.0 0.0 0.0 43.4 43.6 0.0 0.0 10.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.2 0.0 0.0 26.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 23.2 27.6 26.8 21.1 21.0 28.4 23.0 28.4 27.8 25.3 36.4 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.0 0.0 6.3 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.3 0.2 0.7 0.6 1.2 0.0 0.0 157.4 0.0 0.0 2.0 0.0 0.8 0.0 21.9 0.0 0.0 0.1 3.3 69.7 0.0 0.0 0.0 0.3 0.7 0.0 0.1 0.0 472.2 0.0 1.9 0.0 41.7 214.3 1.5 0.0 7.2 0.0 0.0 0.0 5.9 0.0 0.5 0.0 0.5 1.4 0.1 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 SYNPO2 MYOPODIN ENSG00000172403 "Synaptopodin 2" Q9UMS6 4 118850688-119061247 "Predicted intracellular proteins" "Actin-binding, Muscle protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 991.6;tongue: 493.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 135.4;Endometrial stromal cells: 130.0;Excitatory neurons: 149.6;Peritubular cells: 101.5;Sertoli cells: 131.5;Skeletal myocytes: 93.4;Smooth muscle cells: 206.1" "Group enriched" "Detected in all" 5 "prostate cancer: 25.7;stomach cancer: 27.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 57.8;LHCN-M2: 18.5;SH-SY5Y: 83.2" "Region enriched" "Detected in all" 4 "thalamus: 27.1" "Low region specificity" "Detected in all" "HPA030665, CAB037231, HPA049707, HPA068563" Enhanced Enhanced "Vesicles,Actin filaments" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Vesicles, Actin filaments" "CAB037231: AB_262098, HPA030665: AB_10696210, HPA049707: AB_2680857, HPA068563: AB_2686006" "unprognostic (1.50e-2)" "unprognostic (1.73e-2)" "unprognostic (5.32e-2)" "unprognostic (1.50e-2)" "unprognostic (1.81e-1)" "unprognostic (2.39e-1)" "unprognostic (5.71e-4)" "unprognostic (2.18e-1)" "unprognostic (3.07e-1)" "unprognostic (3.52e-1)" "unprognostic (1.39e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (5.67e-5)" "unprognostic (1.82e-2)" "unprognostic (1.35e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.91e-4)" 57.5 10.8 6.1 47.4 7.9 0.3 35.9 4.1 5.7 55.0 2.2 346.4 34.3 137.1 33.4 197.1 89.5 50.0 66.8 10.7 13.3 8.7 7.0 16.2 10.5 5.4 7.5 39.0 3.8 3.6 7.5 20.8 6.1 180.5 58.0 1.2 16.0 267.4 991.6 17.9 75.5 244.4 9.2 10.2 126.2 6.7 5.8 14.3 16.0 493.5 6.5 226.5 54.0 12.0 0.2 4.2 0.2 0.0 10.5 3.5 0.7 13.4 14.1 0.4 0.5 0.0 0.7 1.5 0.1 57.8 0.9 0.2 0.4 0.3 0.7 5.9 0.1 0.8 1.3 0.0 2.4 0.1 0.2 14.5 0.3 4.0 0.2 3.7 0.2 0.2 0.0 0.7 18.5 0.3 0.7 7.2 1.4 0.0 0.0 0.5 1.5 0.4 0.2 0.3 0.4 83.2 0.4 0.3 0.1 3.3 0.0 7.0 0.4 0.6 0.1 0.2 0.1 0.1 0.3 0.1 1.1 0.6 0.2 0.8 0.1 0.5 0.2 0.0 0.4 0.3 0.4 0.2 0.0 0.4 0.4 0.3 0.2 0.3 0.1 0.0 0.5 0.1 6.1 7.9 4.1 5.7 10.7 13.3 5.4 7.5 6.1 9.2 5.8 12.0 25.5 3.2 1.1 42.7 1.1 13.5 17.9 3.7 46.1 2.5 6.3 30.7 135.4 0.0 0.3 1.8 0.0 1.4 0.5 0.1 0.0 0.1 2.2 6.9 130.0 11.3 0.0 1.7 149.6 1.8 0.5 41.5 0.5 10.6 0.0 16.1 13.9 0.4 1.4 0.0 31.5 0.2 0.0 0.9 11.4 7.0 27.1 3.8 5.4 76.8 12.9 0.0 0.0 6.0 3.0 0.2 0.4 101.5 0.8 24.9 0.1 0.3 2.5 0.5 131.5 93.4 206.1 1.3 0.5 5.3 8.1 0.8 2.6 33.4 0.2 4.0 SYT10 ENSG00000110975 "Synaptotagmin 10" Q6XYQ8 12 33374238-33439819 "Predicted membrane proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 6.3;fallopian tube: 2.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 3.9;Distal tubular cells: 7.9;Excitatory neurons: 4.4;Inhibitory neurons: 15.4;Late spermatids: 16.2" "Cancer enriched" "Detected in single" 5 "renal cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.7;K-562: 1.0;MCF7: 3.5;RT4: 1.3;SCLC-21H: 1.7" "Region enhanced" "Detected in all" "olfactory bulb: 49.5" "Low region specificity" "Detected in all" HPA055426 Approved Nucleoplasm,Vesicles NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" "HPA055426: AB_2682812" "unprognostic (3.60e-1)" "unprognostic (4.93e-2)" "unprognostic (9.34e-4)" "unprognostic (5.53e-2)" "unprognostic (3.67e-1)" "unprognostic (4.74e-3)" "unprognostic (3.19e-1)" "unprognostic (1.97e-6)" "unprognostic (4.00e-1)" "unprognostic (2.39e-1)" "unprognostic (2.41e-1)" "unprognostic (1.91e-1)" 0.0 0.3 0.9 0.1 1.9 0.0 0.0 0.0 0.9 0.5 0.4 0.8 0.2 0.0 0.1 0.0 2.2 0.0 0.0 0.6 5.1 0.8 0.3 0.0 0.0 4.1 1.7 0.0 0.0 0.0 0.5 0.0 4.3 0.4 0.4 0.1 0.0 0.7 0.0 0.0 0.3 0.1 2.4 0.0 0.4 0.1 6.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 3.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.8 1.3 1.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.9 0.0 0.9 0.6 5.1 4.1 1.7 4.3 2.4 6.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.1 0.0 0.5 0.0 2.5 0.0 0.0 0.1 0.0 0.0 7.9 0.0 1.5 1.8 0.3 0.1 0.0 0.0 4.4 0.0 0.0 0.3 0.0 1.0 0.0 0.8 1.4 0.0 0.0 0.0 15.4 0.2 0.0 0.0 0.0 16.2 0.3 0.0 0.0 1.0 0.0 0.6 0.0 0.5 0.1 0.0 1.2 0.0 0.0 0.1 0.0 0.1 0.7 0.2 0.0 0.0 0.3 0.2 3.7 0.0 0.0 0.1 0.0 3.2 0.1 0.1 SYT13 KIAA1427 ENSG00000019505 "Synaptotagmin 13" Q7L8C5 11 45240302-45286341 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.1;gallbladder: 20.8;pituitary gland: 16.8" "Cell type enriched" "Detected in many" 7 "Enteroendocrine cells: 336.8" "Group enriched" "Detected in many" 5 "breast cancer: 13.5;colorectal cancer: 7.4;pancreatic cancer: 19.9;renal cancer: 16.9;stomach cancer: 11.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 19.1;NTERA-2: 8.8;RPTEC TERT1: 56.8;SCLC-21H: 15.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046224, HPA056602" Uncertain Supported Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 17: Intestinal endocrine cells - Hormone signaling" Vesicles "HPA046224: AB_10961288, HPA056602: AB_2683185" "unprognostic (4.96e-2)" "unprognostic (1.06e-2)" "unprognostic (9.92e-2)" "prognostic unfavorable (7.79e-5)" "unprognostic (1.00e-2)" "unprognostic (4.17e-2)" "unprognostic (3.75e-2)" "unprognostic (9.83e-3)" "unprognostic (2.19e-1)" "unprognostic (7.58e-2)" "unprognostic (1.21e-1)" "unprognostic (2.47e-1)" "unprognostic (5.66e-3)" "unprognostic (2.94e-2)" "unprognostic (1.76e-1)" "unprognostic (8.70e-2)" "unprognostic (5.13e-2)" 0.1 4.7 7.0 1.5 12.7 0.0 0.2 1.7 30.1 0.0 0.0 12.2 12.5 0.2 0.0 0.0 0.2 20.8 5.2 18.0 11.5 8.9 0.3 0.5 0.0 5.7 1.2 0.0 7.1 0.4 16.8 0.0 5.4 1.8 12.6 11.3 1.9 0.0 0.1 0.2 12.8 0.8 0.0 0.1 11.0 1.7 9.0 0.3 1.6 0.1 0.0 0.0 0.0 5.2 0.0 19.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.2 0.0 1.1 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 8.8 0.0 0.2 0.0 0.0 0.0 56.8 0.0 15.0 0.7 0.0 0.0 0.1 0.7 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 12.7 1.7 30.1 18.0 11.5 5.7 1.2 5.4 0.0 9.0 5.2 0.0 0.0 0.0 4.6 0.1 0.0 0.2 0.0 0.0 3.3 0.1 0.3 15.3 17.2 0.0 3.7 25.0 0.0 0.0 10.2 5.9 1.2 3.1 0.4 0.2 0.1 336.8 0.0 41.6 0.6 0.0 1.7 3.6 2.0 0.0 2.5 0.0 0.0 0.0 1.7 43.8 37.3 4.1 0.0 0.0 9.7 0.3 0.0 0.0 5.6 0.0 0.7 0.0 1.5 3.5 8.2 14.3 0.0 0.0 2.3 13.9 0.5 0.0 2.7 0.0 0.0 0.2 2.0 0.2 0.0 0.0 0.0 0.0 0.0 32.8 0.2 SYT14 "FLJ34198, sytXIV" ENSG00000143469 "Synaptotagmin 14" Q8NB59 1 209900923-210171389 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 7.0;retina: 1.9;testis: 3.2;thyroid gland: 5.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 208.7;Inhibitory neurons: 213.9;Oligodendrocyte precursor cells: 152.8;Oligodendrocytes: 197.6" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.9" "Region enriched" "Detected in some" 4 "cerebellum: 7.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 9.7;GAMG: 6.7;hTERT-HME1: 4.7;SCLC-21H: 6.5;U-138 MG: 6.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036963 Supported Vesicles NA NA "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA036963: AB_10670378" "unprognostic (1.38e-4)" "unprognostic (8.62e-3)" "unprognostic (1.93e-1)" "unprognostic (3.90e-4)" "unprognostic (1.97e-1)" "unprognostic (4.43e-5)" "unprognostic (1.92e-1)" "unprognostic (1.88e-2)" "unprognostic (6.85e-2)" "unprognostic (1.56e-2)" "unprognostic (3.81e-1)" "unprognostic (4.85e-3)" "unprognostic (2.30e-4)" "unprognostic (1.61e-1)" "unprognostic (1.76e-1)" "unprognostic (3.33e-3)" 0.0 0.7 0.4 0.0 0.6 0.0 0.0 7.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.2 0.0 0.6 0.0 0.4 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.2 0.2 0.0 5.0 0.0 0.0 0.0 0.0 1.6 2.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 9.7 2.2 1.2 0.0 0.0 0.0 0.0 0.1 6.7 3.0 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.4 4.7 1.1 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 3.6 0.0 0.3 0.0 0.0 0.0 0.0 1.9 6.5 2.0 0.0 0.0 3.6 0.8 0.0 0.0 1.6 6.4 3.2 0.0 0.9 0.0 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 7.0 1.0 0.4 0.3 0.4 0.2 0.4 0.1 0.2 1.6 0.0 0.0 0.0 30.3 0.0 0.0 0.1 0.0 0.0 30.1 0.2 0.0 2.2 0.0 0.0 0.0 27.1 0.0 0.0 0.0 3.9 0.3 17.0 11.6 2.9 0.2 0.0 0.0 208.7 0.6 0.0 0.2 0.0 29.3 0.0 0.9 0.0 0.0 0.0 52.2 213.9 0.0 0.0 0.0 0.0 5.0 0.6 0.2 0.0 3.7 0.0 1.6 0.0 152.8 197.6 0.3 0.0 0.0 0.0 0.7 0.0 0.4 0.0 29.4 0.0 0.9 0.2 6.0 16.8 0.0 0.0 0.0 0.1 0.7 0.0 0.2 SYT4 "HsT1192, KIAA1342" ENSG00000132872 "Synaptotagmin 4" Q9H2B2 18 43267892-43277535 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 74.7;pituitary gland: 30.7;retina: 25.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 66.8;Cone photoreceptor cells: 22.9;Enteroendocrine cells: 28.7;Excitatory neurons: 50.9;Fibroblasts: 23.0;Inhibitory neurons: 34.1" "Group enriched" "Detected in some" 5 "glioma: 2.0;pancreatic cancer: 4.1;prostate cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "SH-SY5Y: 245.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010574 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Plasma membrane" "HPA010574: AB_2668309" "unprognostic (2.91e-3)" "unprognostic (2.03e-1)" "unprognostic (2.37e-2)" "unprognostic (2.87e-1)" "unprognostic (7.67e-3)" "unprognostic (5.30e-3)" "unprognostic (3.95e-2)" "unprognostic (1.23e-3)" "unprognostic (3.61e-1)" "unprognostic (3.80e-2)" 3.7 15.9 21.5 1.4 18.6 0.1 0.0 74.7 42.6 0.0 0.0 1.2 0.8 0.0 0.0 0.1 0.0 0.0 1.3 18.6 50.4 0.1 0.0 0.9 0.0 10.5 15.3 0.5 3.7 0.0 30.7 0.1 39.3 0.6 0.8 25.2 0.1 8.3 0.0 0.0 0.7 0.6 13.5 0.0 3.2 1.6 18.3 0.4 0.3 0.0 0.0 0.0 0.5 10.9 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 245.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.5 18.6 74.7 42.6 18.6 50.4 10.5 15.3 39.3 13.5 18.3 10.9 0.0 0.0 1.1 8.8 0.0 0.1 0.0 0.0 0.0 66.8 0.0 0.0 3.6 0.0 2.5 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 28.7 0.0 50.9 0.0 0.0 23.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 9.4 0.0 2.5 0.0 7.5 7.6 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.7 10.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 4.9 0.0 0.1 SYT6 ENSG00000134207 "Synaptotagmin 6" Q5T7P8 1 114089291-114153880 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 13.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 7.1;Early spermatids: 6.1;Excitatory neurons: 5.9;Late spermatids: 14.1;Microglial cells: 27.2;Oligodendrocyte precursor cells: 7.5" "Cancer enhanced" "Detected in some" "glioma: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "NTERA-2: 22.0;WM-115: 15.2" "Group enriched" "Detected in all" 7 "basal ganglia: 31.2;olfactory bulb: 71.2" "Low region specificity" "Detected in many" HPA058362 Approved Vesicles NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA058362: " "unprognostic (7.12e-2)" "unprognostic (2.03e-2)" "unprognostic (3.26e-3)" "unprognostic (1.04e-1)" "unprognostic (9.37e-2)" "unprognostic (2.49e-1)" "unprognostic (4.11e-2)" "unprognostic (3.60e-3)" "unprognostic (1.19e-1)" "unprognostic (4.71e-1)" "unprognostic (5.50e-2)" "unprognostic (1.01e-1)" "unprognostic (2.82e-1)" "unprognostic (2.11e-3)" "unprognostic (1.48e-1)" "unprognostic (1.48e-2)" "unprognostic (1.18e-1)" 0.0 0.8 2.7 0.2 4.2 0.0 0.7 1.5 2.8 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.0 3.0 13.5 1.5 0.0 0.0 0.0 4.8 4.5 0.8 3.1 0.1 0.1 0.5 3.9 0.4 0.1 1.4 0.0 0.0 0.1 0.0 0.0 0.0 7.9 0.0 0.0 0.3 9.5 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 22.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.7 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 4.2 1.5 2.8 3.0 13.5 4.8 4.5 3.9 7.9 9.5 4.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 7.1 0.1 0.3 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 6.1 0.0 0.2 0.3 0.0 0.0 5.9 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.4 0.0 2.4 0.0 0.0 0.0 0.4 14.1 0.0 1.2 3.6 27.2 0.0 0.7 0.0 7.5 0.6 0.0 0.0 0.0 0.0 0.3 0.0 4.3 0.0 0.7 0.0 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.1 3.9 0.0 0.0 SYTL3 "exophilin-6, SLP3" ENSG00000164674 "Synaptotagmin like 3" Q4VX76 6 158650014-158764876 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 334.2;granulocytes: 135.4;NK-cells: 132.8;Plasma cells: 135.2;T-cells: 230.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 232.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 232.0" "Cell line enhanced" "Detected in many" "HMC-1: 23.9;U-138 MG: 18.9;U-2 OS: 19.1;U-266/70: 28.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030584, HPA030585, HPA030586" Approved Approved "Nucleoli fibrillar center,Vesicles" NA Yes "Cluster 38: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoli fibrillar center, Vesicles" "HPA030584: AB_10600196, HPA030585: AB_10601239, HPA030586: AB_10601226" "unprognostic (3.56e-3)" "prognostic favorable (8.84e-5)" "unprognostic (6.37e-2)" "unprognostic (1.96e-3)" "unprognostic (3.88e-2)" "unprognostic (1.42e-1)" "unprognostic (7.76e-2)" "unprognostic (5.45e-3)" "unprognostic (9.33e-3)" "unprognostic (1.75e-1)" "unprognostic (3.07e-1)" "unprognostic (5.63e-2)" "unprognostic (8.58e-3)" "unprognostic (1.55e-1)" "unprognostic (6.28e-2)" "unprognostic (2.80e-2)" "unprognostic (1.83e-1)" 5.5 1.8 1.5 7.5 1.7 13.9 4.3 2.2 1.6 6.0 23.9 4.2 3.8 3.5 6.4 4.0 14.4 4.8 7.1 2.3 2.7 5.3 2.5 16.8 8.4 3.8 2.9 2.8 1.5 1.8 2.1 1.6 3.4 5.4 2.4 0.4 15.3 5.8 14.9 3.3 9.9 2.8 2.9 19.8 7.1 3.8 2.9 17.4 25.2 8.2 6.0 5.0 3.6 4.6 7.1 1.0 0.1 0.5 0.9 0.9 0.4 3.1 2.0 0.8 2.1 0.6 5.8 0.1 0.5 5.3 2.6 0.8 0.1 0.9 2.9 15.1 0.4 5.8 0.2 0.0 1.7 1.7 23.9 3.1 2.1 6.1 1.0 2.6 1.4 1.1 0.3 5.6 6.8 0.3 0.1 2.0 0.1 1.3 1.0 0.0 5.6 0.7 2.8 0.4 15.6 1.2 1.0 9.7 0.8 0.3 2.0 0.3 8.8 18.9 19.1 0.5 0.6 28.5 7.1 0.6 12.0 8.3 0.6 232.0 16.0 0.8 37.3 3.3 22.0 1.0 14.7 25.3 4.6 0.3 15.7 19.3 35.5 43.1 1.4 1.3 16.4 18.9 1.5 1.7 2.2 1.6 2.3 2.7 3.8 2.9 3.4 2.9 2.9 4.6 2.8 16.0 13.1 2.3 23.5 4.6 2.9 4.4 1.8 0.2 4.4 3.7 4.1 1.5 15.9 14.7 2.1 1.3 334.2 1.0 5.9 0.8 10.8 51.0 3.0 4.2 0.0 4.4 3.4 0.6 0.5 4.8 17.3 37.4 135.4 0.4 3.9 1.9 4.2 0.0 4.8 1.8 4.1 11.5 20.3 18.1 0.0 26.6 10.6 28.1 17.6 0.1 132.8 2.0 2.5 0.6 0.1 0.7 135.2 1.8 2.0 1.9 51.5 0.5 0.0 2.3 2.4 2.1 8.4 2.6 4.4 1.9 230.2 0.9 1.3 3.1 SYTL4 ENSG00000102362 "Synaptotagmin like 4" Q96C24 X 100674491-100732123 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 68.3" "Cell type enhanced" "Detected in many" "Granulosa cells: 58.1;Leydig cells: 72.7;Sertoli cells: 52.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.7" "Lineage enriched" "Detected in single" 10 "granulocytes: 1.7" "Cell line enhanced" "Detected in many" "HAP1: 29.5;HMC-1: 60.0;RT4: 40.8;TIME: 34.9" "Region enriched" "Detected in many" 5 "hypothalamus: 30.1" "Low region specificity" "Detected in all" "HPA001475, HPA001589, HPA075138" Approved Approved Vesicles NA Yes 3300000 "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA001475: AB_1080172, HPA001589: AB_1080174, HPA075138: " "unprognostic (7.82e-3)" "unprognostic (1.52e-1)" "unprognostic (3.43e-2)" "unprognostic (6.16e-2)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (5.78e-2)" "unprognostic (1.32e-1)" "unprognostic (3.35e-2)" "unprognostic (2.81e-1)" "unprognostic (1.07e-3)" "unprognostic (5.62e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (1.30e-1)" "unprognostic (1.56e-1)" "unprognostic (1.67e-1)" "unprognostic (1.60e-2)" 6.9 4.1 6.9 2.2 13.2 2.3 6.0 4.5 5.1 21.7 14.1 9.8 2.1 43.1 3.1 3.9 17.8 4.0 3.2 5.2 13.1 5.6 10.5 4.7 0.7 8.4 9.3 68.3 8.3 1.2 18.8 3.6 7.4 12.7 9.7 1.3 6.1 7.2 2.3 2.0 4.9 32.7 6.1 3.3 7.4 6.8 18.0 0.6 8.8 4.9 1.7 6.1 10.2 7.9 0.3 6.0 1.6 0.0 8.5 4.8 0.1 7.7 4.9 8.0 14.3 0.7 7.6 0.0 2.0 5.4 6.9 6.8 29.5 2.3 8.4 0.0 2.6 0.1 10.8 0.4 2.1 0.0 60.0 1.7 0.5 7.3 0.4 3.1 20.5 0.0 3.0 0.0 3.8 2.0 0.1 0.0 1.2 21.2 0.0 0.0 2.4 0.0 7.0 40.8 14.5 0.6 3.1 11.5 1.7 3.0 7.1 0.6 34.9 4.2 8.8 20.9 1.9 0.1 0.0 0.1 5.2 0.0 4.8 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 1.7 0.1 0.0 0.0 0.0 0.8 6.9 13.2 4.5 5.1 5.2 13.1 8.4 9.3 7.4 6.1 18.0 7.9 15.6 28.9 1.7 41.8 0.5 0.1 7.7 3.1 1.2 0.2 19.0 6.6 3.8 18.6 8.0 3.7 0.0 0.4 0.7 29.1 3.9 8.9 1.6 4.3 25.8 13.5 0.0 5.0 0.5 2.3 0.4 20.0 26.5 6.2 3.8 58.1 11.4 38.6 1.3 0.0 1.0 26.9 8.2 1.6 1.9 3.8 72.7 7.2 3.6 8.4 0.5 5.4 0.0 10.6 0.2 7.2 27.1 41.8 0.5 11.9 5.8 2.6 8.1 0.6 52.6 38.1 11.8 2.6 4.4 2.6 0.9 0.0 0.9 18.0 9.6 13.8 SZT2 "C1orf84, FLJ10387, FLJ34502, KIAA0467, RP11-506B15.1, SZT2A, SZT2B" ENSG00000198198 "SZT2 subunit of KICSTOR complex" Q5T011 1 43389882-43454247 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 62.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029012 Approved Approved "Nucleoplasm,Vesicles,Actin filaments" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles, Actin filaments" "HPA029012: AB_10600817" "unprognostic (1.35e-1)" "unprognostic (2.55e-1)" "unprognostic (4.14e-1)" "unprognostic (6.61e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.47e-7)" "prognostic unfavorable (2.53e-4)" "prognostic favorable (6.20e-4)" "unprognostic (1.54e-1)" "unprognostic (1.81e-2)" "unprognostic (5.96e-2)" "unprognostic (1.03e-1)" "unprognostic (1.05e-2)" "unprognostic (1.84e-3)" "unprognostic (8.28e-2)" "unprognostic (7.19e-2)" "unprognostic (2.61e-2)" 6.3 5.3 1.3 4.3 2.5 6.0 6.2 3.2 3.1 6.1 0.8 6.7 3.4 7.2 2.6 5.9 7.0 2.7 5.4 1.1 2.1 4.7 4.4 6.4 4.2 2.9 2.3 8.0 6.5 5.6 8.8 2.7 2.5 6.5 3.4 4.0 6.5 3.2 6.6 7.7 7.9 3.6 0.9 7.1 6.4 9.6 3.0 4.4 9.0 3.9 4.1 6.2 5.8 5.0 4.5 4.4 3.7 3.4 9.1 4.5 5.7 3.7 4.4 4.5 4.1 1.5 5.0 4.1 4.1 5.9 3.2 5.1 3.7 6.3 3.9 5.1 3.4 7.5 8.1 2.7 3.4 6.1 6.2 4.8 4.2 7.7 7.5 5.0 5.2 4.7 3.4 6.8 3.2 2.1 4.1 1.6 3.3 2.7 4.5 4.5 5.1 4.9 2.6 6.2 3.8 3.4 7.8 5.9 4.0 4.8 3.2 8.8 6.5 4.8 6.8 6.4 6.5 7.3 2.8 3.4 4.9 3.8 3.1 1.4 0.5 1.4 0.3 0.4 0.8 0.3 0.1 0.1 0.4 0.3 0.4 0.3 1.1 0.3 0.5 0.9 0.4 0.2 1.3 2.5 3.2 3.1 1.1 2.1 2.9 2.3 2.5 0.9 3.0 5.0 8.3 25.6 19.3 19.6 10.5 1.9 3.5 5.1 6.2 16.8 7.7 7.0 4.8 5.7 6.8 5.5 62.6 6.5 9.2 10.0 0.0 6.1 14.2 5.8 10.1 7.6 3.6 5.5 20.4 6.4 5.2 7.0 13.7 6.9 14.5 19.0 12.8 13.1 5.4 13.5 20.2 7.0 4.1 7.0 3.1 15.8 9.3 9.4 5.4 15.9 11.6 5.8 13.4 11.1 29.1 6.8 3.7 6.0 9.5 4.2 10.5 9.2 8.0 22.2 19.7 9.1 7.1 8.1 8.6 4.2 1.8 5.5 11.4 12.6 7.0 3.8 TAC3 "LncZBTB39, LncZBTB39-1:2, NK3, NKB, NKNB, ZNEUROK1" ENSG00000166863 "Tachykinin precursor 3" Q9UHF0 12 57010000-57028883 "Disease related genes, Human disease related genes, Predicted secreted proteins" Neuropeptide "Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "placenta: 431.7" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 13.9;Extravillous trophoblasts: 19.6;Inhibitory neurons: 40.0;Syncytiotrophoblasts: 18.3" "Cancer enriched" "Detected in many" 7 "urothelial cancer: 40.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "K-562: 14.4;SuSa: 13.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA045919 Supported Supported Approved Vesicles "Secreted in female reproductive system" NA NA 130000 "Cluster 28: Placenta - Pregnancy" "Cluster 1: K-562 - Erythropoiesis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA045919: AB_10960533" "unprognostic (4.53e-2)" "unprognostic (1.97e-2)" "unprognostic (8.41e-2)" "unprognostic (3.00e-2)" "unprognostic (3.61e-2)" "unprognostic (1.76e-2)" "unprognostic (5.99e-2)" "unprognostic (8.41e-2)" "unprognostic (1.34e-1)" "unprognostic (2.03e-1)" "unprognostic (5.28e-2)" "unprognostic (4.71e-14)" "unprognostic (1.58e-2)" "unprognostic (1.76e-1)" "unprognostic (1.01e-1)" "unprognostic (2.39e-1)" 0.1 0.3 15.2 2.5 11.0 1.0 0.1 5.2 16.5 0.1 5.6 3.8 3.0 0.3 0.0 0.1 0.0 0.3 0.1 11.2 25.1 0.1 0.1 0.1 0.2 16.8 7.7 0.2 0.6 0.0 0.7 431.7 7.7 0.2 1.5 6.1 0.0 0.0 0.2 0.5 6.5 4.8 27.3 0.1 13.1 1.8 6.2 0.5 0.1 0.0 0.4 3.1 0.3 9.8 0.0 0.1 0.0 0.4 0.0 0.0 1.2 0.0 1.1 0.3 0.0 1.6 0.0 0.7 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 1.3 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.3 14.4 0.3 0.0 0.0 0.0 0.2 1.6 0.5 0.0 0.0 0.0 0.0 0.0 1.5 2.1 0.6 0.0 0.8 0.0 13.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 11.0 5.2 16.5 11.2 25.1 16.8 7.7 7.7 27.3 6.2 9.8 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.5 0.3 0.0 0.0 0.0 0.0 13.9 0.0 1.4 0.0 0.0 0.1 0.0 0.4 0.1 1.2 2.7 0.5 0.0 19.6 2.6 0.0 0.1 0.0 4.3 0.7 0.0 2.2 0.0 40.0 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.5 2.8 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.4 2.6 1.0 0.0 0.0 18.3 0.0 0.0 1.8 0.0 TACC3 "ERIC-1, ERIC1, maskin, Tacc4" ENSG00000013810 "Transforming acidic coiled-coil containing protein 3" Q9Y6A5 4 1712891-1745171 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 58.9;lymphoid tissue: 52.4;testis: 50.6" "Cell type enhanced" "Detected in many" "Early spermatids: 70.4;Hofbauer cells: 43.9;Late spermatids: 69.9;Spermatocytes: 94.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005781, HPA006050, CAB010111, HPA022039" Enhanced Enhanced "Vesicles,Mitotic spindle,Centriolar satellite,Cytosol" Yes Yes 11000 "Cluster 5: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Mitotic spindle, Centriolar satellite, Cytosol" Vesicles "CAB010111: AB_628323, HPA005781: AB_1857724, HPA006050: AB_2667505, HPA022039: AB_1857725" "unprognostic (2.95e-1)" "unprognostic (1.18e-1)" "unprognostic (7.71e-2)" "unprognostic (4.35e-2)" "unprognostic (6.58e-2)" "unprognostic (1.84e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (1.10e-3)" "unprognostic (4.61e-2)" "unprognostic (9.12e-2)" "unprognostic (2.91e-2)" "unprognostic (2.26e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (4.66e-2)" "unprognostic (2.09e-1)" "unprognostic (4.44e-3)" "unprognostic (9.75e-2)" 5.3 3.9 4.2 24.9 4.3 58.9 3.5 5.2 5.3 3.6 5.2 10.3 6.6 3.3 4.8 14.9 2.8 4.2 3.3 4.5 4.4 2.7 3.5 6.5 43.2 4.8 5.3 2.2 1.4 2.3 2.6 8.7 4.8 2.4 10.6 1.9 3.9 2.5 2.0 6.4 12.9 6.4 4.2 22.1 6.4 50.6 5.1 52.4 2.8 3.4 39.3 5.0 5.4 4.7 106.7 88.7 129.5 72.2 6.7 15.2 72.9 114.6 62.1 135.4 87.6 93.5 122.8 133.8 48.0 65.4 149.9 71.4 142.5 86.8 131.1 59.8 77.0 113.8 67.2 85.8 5.9 146.6 85.5 5.2 5.7 85.6 46.0 26.0 102.2 110.3 106.3 90.8 123.8 87.1 207.5 204.0 139.3 89.2 111.6 139.1 90.5 55.0 73.8 125.5 99.8 62.8 70.1 42.3 33.1 95.2 83.3 90.5 56.4 75.4 90.0 65.4 176.7 69.5 102.5 207.1 43.2 141.1 109.1 45.5 30.0 37.9 8.5 12.5 11.1 7.8 16.5 11.5 15.3 10.8 28.3 13.1 91.8 12.2 9.6 8.3 42.5 32.5 4.2 4.3 5.2 5.3 4.5 4.4 4.8 5.3 4.8 4.2 5.1 4.7 6.0 0.0 6.7 2.0 16.5 2.2 1.2 3.2 1.2 1.7 2.4 3.0 2.6 2.8 3.4 9.2 8.4 19.5 6.4 11.2 0.0 2.2 70.4 4.2 2.8 5.2 1.2 37.2 2.3 0.7 20.4 6.0 12.8 4.3 5.1 24.5 8.9 5.1 43.9 5.0 3.2 9.5 4.1 23.2 10.8 69.9 2.8 34.1 0.0 4.7 24.4 1.4 6.2 0.5 0.8 2.9 4.2 2.6 18.0 1.3 2.6 2.8 0.9 2.7 6.6 2.0 4.8 94.3 37.7 12.8 1.4 4.0 23.2 2.2 16.1 2.7 TACSTD2 "EGP-1, GA733-1, M1S1, TROP2" ENSG00000184292 "Tumor associated calcium signal transducer 2" P09758 1 58575433-58577252 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Tumor antigen" "Amyloidosis, Corneal dystrophy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 989.6;salivary gland: 468.5;skin 1: 438.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 6559.0;Basal respiratory cells: 3141.0;Club cells: 2499.0;Prostatic glandular cells: 3724.1;Squamous epithelial cells: 2716.6;Urothelial cells: 8102.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 15.0" "Group enriched" "Detected in many" 79 "dendritic cells: 4.3;granulocytes: 15.0;monocytes: 4.2" "Cell line enhanced" "Detected in many" "A-431: 766.6;CAPAN-2: 1005.9;HaCaT: 1010.0;RT4: 355.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA043104, HPA055067, CAB072852" Enhanced Supported "Nucleoli,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "Nucleoli, Vesicles" "CAB072852: , HPA043104: AB_10960710, HPA055067: AB_2682687" "unprognostic (1.80e-2)" "unprognostic (3.08e-1)" "unprognostic (3.67e-3)" "unprognostic (1.22e-1)" "unprognostic (5.70e-2)" "unprognostic (2.15e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (1.99e-1)" "unprognostic (1.03e-2)" "unprognostic (1.71e-2)" "unprognostic (7.91e-2)" "prognostic favorable (3.99e-4)" "unprognostic (7.10e-2)" "unprognostic (2.55e-1)" "unprognostic (6.91e-3)" "unprognostic (2.50e-1)" 4.8 1.2 0.2 1.3 0.4 13.5 135.8 0.2 0.4 218.6 1.9 1.1 0.7 19.1 25.3 989.6 27.7 13.0 0.8 0.3 0.3 137.9 4.0 71.2 1.0 0.2 0.3 1.5 81.1 3.5 2.4 17.7 0.2 126.8 0.9 0.0 468.5 97.1 1.9 438.8 1.2 2.0 0.2 1.0 65.7 0.5 0.3 9.2 5.0 0.3 180.0 234.6 375.0 0.6 766.6 0.1 0.0 1.5 0.0 0.0 280.1 0.2 0.0 0.0 0.1 0.7 1005.9 0.1 94.7 64.2 0.1 1010.0 0.0 186.5 0.0 0.7 0.0 0.2 19.7 0.3 0.3 0.1 0.8 0.2 274.5 0.4 11.3 0.0 42.5 0.0 0.2 1.3 0.0 166.3 0.6 1.1 0.5 167.0 1.4 0.2 0.1 0.6 137.0 355.3 0.2 0.3 32.4 264.9 1.0 3.2 173.6 1.5 45.4 1.0 1.7 0.8 1.7 0.4 0.9 0.7 1.0 0.3 0.7 0.0 4.2 15.0 0.0 0.1 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 1.8 0.2 0.4 0.2 0.4 0.3 0.3 0.2 0.3 0.2 0.2 0.3 0.6 9.0 346.1 109.2 0.0 3.1 1490.5 6559.0 3141.0 1226.5 0.0 789.8 445.6 0.4 338.8 2499.0 1278.2 0.0 107.1 9.1 2.8 43.0 2165.2 0.0 482.3 48.6 60.4 0.0 0.0 0.1 1263.4 8.1 36.3 143.2 608.7 8.8 0.2 1.4 0.5 8.8 0.0 0.0 8.5 1143.4 0.8 203.4 0.0 0.0 34.8 113.8 0.0 31.3 0.0 0.0 0.0 0.6 1778.0 3.6 0.0 1.4 3724.1 0.2 3.4 1080.4 0.0 0.0 1.3 142.4 0.4 1.1 2716.6 1531.8 78.4 32.8 0.0 1.5 8102.8 TAMALIN GRASP ENSG00000161835 "Trafficking regulator and scaffold protein tamalin" Q7Z6J2 12 52006946-52015889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 243.8;B-cells: 60.6;dendritic cells: 114.1;Macrophages: 60.6;Plasma cells: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 37.4;TIME: 27.4;WM-115: 50.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040664, HPA062028" Approved Approved "Nuclear bodies,Vesicles" No NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 65: Plasmacytoid DCs - Unknown function" Vesicles "Nuclear bodies" "HPA040664: AB_10794066, HPA062028: AB_2684664" "unprognostic (1.90e-1)" "unprognostic (1.29e-2)" "unprognostic (2.48e-2)" "unprognostic (2.39e-2)" "unprognostic (2.00e-2)" "unprognostic (2.38e-2)" "unprognostic (2.23e-2)" "unprognostic (1.93e-1)" "unprognostic (2.86e-1)" "unprognostic (8.71e-2)" "unprognostic (3.16e-3)" "unprognostic (7.20e-2)" "unprognostic (3.90e-3)" "unprognostic (1.99e-3)" "unprognostic (1.44e-1)" "unprognostic (3.53e-2)" "unprognostic (2.77e-2)" 31.9 6.3 9.8 4.1 14.9 23.8 26.9 3.2 21.5 17.6 0.4 9.4 2.2 22.0 1.6 7.1 22.2 9.6 24.2 10.5 3.7 12.2 4.2 46.8 3.8 5.0 4.9 14.9 5.7 2.8 6.2 8.9 4.8 13.0 1.9 0.1 6.5 3.1 10.6 10.7 9.8 6.0 4.1 18.2 8.6 2.6 7.6 3.7 16.3 8.4 2.3 12.5 17.1 7.1 0.0 0.0 4.4 0.2 1.9 3.6 1.0 0.2 1.1 0.0 1.1 0.0 0.0 0.0 10.0 0.0 0.4 0.1 1.3 0.0 0.4 0.2 1.3 0.3 0.0 6.2 7.4 0.3 3.3 7.2 0.0 0.3 0.0 0.0 37.4 1.0 1.6 0.0 0.9 0.2 3.1 10.5 4.0 0.0 0.2 0.1 0.8 0.0 0.0 0.0 1.1 1.6 0.0 0.2 7.5 2.7 0.0 0.3 27.4 0.0 2.5 0.2 0.0 0.2 0.0 0.1 0.6 0.0 50.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 9.8 14.9 3.2 21.5 10.5 3.7 5.0 4.9 4.8 4.1 7.6 7.1 243.8 0.0 0.0 0.0 60.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.2 114.1 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.2 5.8 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.3 5.4 0.0 0.0 0.0 TAOK1 "FLJ14314, KIAA1361, MAP3K16, MARKK, PSK2, TAO1" ENSG00000160551 "TAO kinase 1" Q7L7X3 17 29390363-29551903 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 220.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007669 Approved Uncertain Vesicles NA NA 1600000 "Cluster 1: Neutrophils - Mixed function" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA007669: AB_1080201" "unprognostic (1.46e-1)" "unprognostic (7.15e-3)" "unprognostic (2.70e-2)" "unprognostic (1.52e-1)" "unprognostic (1.81e-2)" "unprognostic (4.85e-2)" "unprognostic (1.28e-2)" "unprognostic (4.31e-2)" "unprognostic (1.15e-1)" "unprognostic (6.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.36e-1)" "unprognostic (2.85e-2)" "unprognostic (5.53e-3)" "unprognostic (3.57e-1)" "unprognostic (1.66e-1)" "unprognostic (2.62e-1)" 13.7 9.1 12.0 9.8 16.0 10.5 10.3 13.8 13.1 11.8 1.2 9.5 5.2 10.8 8.5 10.3 7.9 9.6 13.2 13.3 12.8 10.2 8.6 9.8 9.9 16.4 14.5 10.3 7.8 19.4 8.0 11.7 14.9 9.0 8.5 20.9 7.8 10.0 11.4 10.4 7.3 11.7 13.2 10.4 8.1 11.7 13.9 13.2 14.5 15.2 9.5 12.1 8.7 20.4 19.3 35.0 32.1 13.4 24.1 29.8 11.3 20.0 23.9 20.3 21.1 20.7 7.9 13.8 15.8 35.9 20.7 16.3 30.4 15.7 36.4 20.7 18.2 21.0 21.3 12.2 16.6 26.5 16.7 19.4 19.6 29.0 30.6 21.3 27.3 14.0 20.7 12.0 26.7 14.2 18.5 9.5 12.0 12.9 8.6 15.1 41.2 8.8 19.1 31.5 16.1 18.7 34.6 34.4 21.1 32.6 23.6 21.6 33.6 28.0 19.7 23.7 27.5 9.3 18.6 14.0 20.3 14.8 24.3 0.6 0.5 0.5 0.6 0.6 0.5 0.5 0.6 0.7 0.5 0.6 0.7 0.7 1.7 0.5 0.6 1.4 0.4 0.3 12.0 16.0 13.8 13.1 13.3 12.8 16.4 14.5 14.9 13.2 13.9 20.4 96.9 48.1 45.8 105.8 35.9 44.5 27.4 27.0 52.9 56.6 35.5 23.2 90.2 30.0 37.7 46.0 98.0 18.7 40.5 29.3 15.6 27.3 11.8 45.0 72.0 55.4 37.7 18.7 162.3 24.3 16.0 58.0 31.6 80.1 28.5 44.3 52.1 29.5 30.1 52.2 160.5 23.7 24.4 65.6 60.4 19.8 39.7 67.3 40.9 92.8 55.8 37.1 29.9 142.2 220.8 38.9 24.0 54.2 34.2 40.4 17.6 22.1 31.0 54.7 26.3 66.1 52.1 59.1 33.2 49.5 45.9 37.6 43.1 43.0 21.1 41.6 TAS2R10 "T2R10, TRB2" ENSG00000121318 "Taste 2 receptor member 10" Q9NYW0 12 10825317-10826358 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Astrocytes: 6.2;Excitatory neurons: 14.4;Inhibitory neurons: 14.4;Microglial cells: 4.7;Oligodendrocyte precursor cells: 14.1;Oligodendrocytes: 11.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA070201 Approved "Vesicles,Plasma membrane,Actin filaments" NA NA "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane" "Actin filaments" "HPA070201: " "unprognostic (1.28e-1)" "unprognostic (3.89e-4)" "unprognostic (1.77e-1)" "unprognostic (1.82e-2)" "unprognostic (1.10e-1)" "unprognostic (5.82e-3)" "unprognostic (3.86e-1)" "unprognostic (7.72e-2)" "unprognostic (5.27e-2)" "unprognostic (1.67e-1)" "unprognostic (1.24e-2)" "unprognostic (1.20e-1)" "unprognostic (4.16e-5)" "unprognostic (5.41e-2)" "unprognostic (3.18e-2)" "unprognostic (2.87e-2)" "unprognostic (2.56e-3)" 0.2 0.6 0.1 0.0 0.1 0.0 0.2 0.1 0.4 0.3 0.0 0.2 0.0 0.4 0.1 0.1 0.1 0.0 0.2 0.1 0.0 0.2 0.3 0.2 0.0 0.1 0.1 0.3 0.2 0.0 0.4 0.0 0.1 0.2 0.0 0.3 0.4 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 6.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 14.4 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.7 0.0 0.1 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 14.1 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 TASL "CXorf21, FLJ11577" ENSG00000120280 "TLR adaptor interacting with endolysosomal SLC15A4" Q9HAI6 X 30558809-30577766 "Disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.5;lymphoid tissue: 10.9" "Cell type enriched" "Detected in some" 5 "Hofbauer cells: 22.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in some" 7 "THP-1: 166.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA001185 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm Vesicles "HPA001185: AB_1078591" "unprognostic (1.37e-1)" "unprognostic (2.52e-2)" "unprognostic (4.37e-2)" "unprognostic (2.27e-2)" "unprognostic (3.47e-2)" "unprognostic (5.25e-3)" "unprognostic (9.07e-3)" "unprognostic (5.94e-3)" "unprognostic (1.15e-1)" "unprognostic (1.40e-1)" "unprognostic (3.43e-1)" "unprognostic (3.60e-1)" "unprognostic (1.66e-3)" "unprognostic (8.99e-2)" "unprognostic (1.98e-2)" "unprognostic (3.45e-2)" "unprognostic (3.23e-2)" 1.8 1.8 0.6 10.9 0.6 19.5 2.1 0.7 1.0 1.1 1.1 3.5 4.7 0.6 0.4 1.6 0.8 3.9 0.6 0.7 0.6 1.1 2.4 4.7 10.5 1.3 1.1 0.3 0.3 0.7 0.3 2.9 1.3 1.0 3.4 0.2 1.0 0.6 0.1 0.7 3.0 2.2 0.9 9.8 3.6 0.3 1.5 5.8 0.6 0.4 10.2 4.1 0.3 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.3 0.2 0.0 0.0 13.8 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.2 0.0 0.0 0.0 21.5 0.0 0.0 0.0 20.5 0.0 21.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 166.0 0.0 0.0 0.0 0.0 0.1 15.0 1.6 7.5 0.0 23.9 0.0 8.6 21.9 24.1 1.6 19.8 0.3 23.0 2.0 1.1 25.3 23.6 1.8 1.3 30.6 7.1 44.4 45.9 3.4 8.0 0.6 0.6 0.7 1.0 0.7 0.6 1.3 1.1 1.3 0.9 1.5 2.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 TAX1BP3 TIP-1 ENSG00000213977 "Tax1 binding protein 3" O14907 17 3662895-3668679 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 395.9;Ductal cells: 351.0;Exocrine glandular cells: 385.9;Pancreatic endocrine cells: 505.8;Paneth cells: 362.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 164.3;granulocytes: 217.8;monocytes: 78.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046410, HPA063078" Approved Approved "Nucleoli fibrillar center,Vesicles,Actin filaments" NA NA 120000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli fibrillar center" "Vesicles, Actin filaments" "HPA046410: AB_2679656, HPA063078: AB_2684937" "unprognostic (6.15e-2)" "unprognostic (6.46e-3)" "unprognostic (3.37e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (2.17e-4)" "unprognostic (1.68e-1)" "unprognostic (1.12e-3)" "prognostic unfavorable (1.76e-4)" "unprognostic (1.80e-2)" "unprognostic (5.45e-3)" "unprognostic (5.19e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (7.90e-4)" "unprognostic (5.12e-2)" "unprognostic (2.10e-1)" "unprognostic (2.10e-3)" "unprognostic (1.92e-1)" 107.3 131.8 62.7 49.2 78.5 16.5 94.4 67.9 67.3 192.9 48.2 108.5 108.8 128.1 33.6 258.5 84.4 90.9 194.8 57.3 58.8 115.0 39.7 94.9 39.3 72.5 73.3 95.9 80.4 23.5 30.9 53.2 69.9 91.7 77.4 3.7 109.7 105.6 28.7 120.4 119.6 70.3 66.2 52.3 136.5 51.2 65.2 44.6 63.6 33.4 49.0 102.8 160.1 80.6 183.1 319.1 68.4 38.5 219.2 175.6 81.3 223.6 184.5 234.0 136.7 135.9 144.5 19.1 159.1 290.8 77.2 282.6 39.1 205.3 90.8 50.7 64.4 25.9 75.8 106.6 191.1 4.3 37.7 267.6 322.5 145.1 68.9 165.3 266.0 50.1 9.6 14.4 280.1 169.4 52.2 15.1 65.9 116.7 112.6 50.0 41.8 16.3 248.6 141.2 14.7 43.2 276.2 116.2 39.4 67.5 125.3 23.2 269.6 195.3 75.2 154.9 230.2 5.7 2.6 5.5 117.4 30.0 190.3 217.8 65.4 120.4 26.9 78.9 22.2 29.2 25.0 26.6 58.7 25.3 17.3 22.7 73.8 20.0 73.6 164.3 36.7 53.3 62.7 78.5 67.9 67.3 57.3 58.8 72.5 73.3 69.9 66.2 65.2 80.6 51.5 60.9 25.8 0.0 19.0 95.3 79.7 229.3 99.6 1.6 51.0 28.2 41.5 92.9 107.6 99.3 0.0 124.7 68.5 395.9 88.0 351.0 16.2 12.8 27.3 77.0 24.6 21.4 0.0 385.9 145.3 72.6 43.8 16.1 26.6 21.2 75.3 11.1 69.8 5.0 0.0 120.0 71.2 35.2 73.2 10.5 174.6 64.0 113.8 0.0 85.5 19.8 26.8 0.0 0.0 505.8 362.8 209.9 5.8 89.0 279.2 185.3 26.8 2.6 39.5 44.1 78.6 8.6 12.8 94.5 76.0 155.6 16.1 92.0 103.0 107.9 TBC1D14 KIAA1322 ENSG00000132405 "TBC1 domain family member 14" Q9P2M4 4 6909242-7033118 "Plasma proteins, Predicted intracellular proteins" Autophagy "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 68.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 197.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036930, HPA067398" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" Nucleoplasm "HPA036930: AB_10670155, HPA067398: AB_2685833" "unprognostic (3.05e-2)" "unprognostic (7.48e-3)" "unprognostic (4.80e-3)" "unprognostic (8.13e-2)" "unprognostic (2.83e-1)" "unprognostic (1.78e-3)" "unprognostic (9.63e-2)" "unprognostic (5.25e-2)" "unprognostic (9.71e-2)" "unprognostic (7.65e-2)" "unprognostic (1.80e-1)" "unprognostic (2.90e-1)" "prognostic favorable (5.28e-10)" "unprognostic (1.56e-1)" "unprognostic (3.50e-1)" "unprognostic (5.13e-3)" "unprognostic (4.12e-2)" 26.3 42.1 42.7 31.5 41.9 15.9 27.6 38.7 43.9 19.4 50.2 26.4 22.8 20.9 22.9 34.0 23.5 17.0 30.4 42.9 44.9 44.5 27.4 24.4 29.8 49.3 45.6 28.7 19.5 41.9 27.1 23.8 44.8 24.5 26.3 18.5 31.7 20.2 51.6 49.5 26.0 22.9 45.7 34.9 58.5 30.0 48.7 40.1 19.2 41.3 26.9 19.8 22.2 44.2 34.5 36.8 40.4 45.5 32.8 27.4 24.5 27.0 29.3 24.7 21.1 38.3 69.8 54.9 15.6 32.5 62.8 24.5 68.4 61.7 30.0 15.5 22.2 91.8 23.8 40.4 22.7 42.0 197.9 21.3 85.8 23.4 38.3 31.5 23.5 51.2 88.6 19.3 30.2 22.3 64.9 42.5 54.9 41.1 40.8 80.2 53.2 59.9 36.8 23.9 61.6 44.0 22.4 24.1 84.3 31.2 33.3 39.4 23.7 27.2 20.5 24.0 40.3 36.7 91.6 55.7 25.4 53.2 26.6 2.6 13.2 5.6 8.6 8.2 13.1 8.1 9.3 9.3 10.7 8.3 6.9 6.6 40.6 8.6 3.9 11.5 11.9 10.8 42.7 41.9 38.7 43.9 42.9 44.9 49.3 45.6 44.8 45.7 48.7 44.2 8.4 6.4 17.7 22.5 15.5 9.1 7.0 15.8 15.9 10.2 21.1 16.3 4.6 10.0 14.8 14.7 14.6 12.5 16.3 17.7 19.6 11.5 68.0 12.3 10.3 7.8 6.6 7.2 25.6 10.2 7.1 9.5 14.8 11.9 7.6 18.9 8.2 24.4 26.0 25.2 25.1 15.7 10.2 33.6 8.7 41.0 7.2 27.8 19.6 27.2 24.4 13.4 16.5 51.8 27.0 11.8 14.2 8.6 15.4 12.9 12.8 19.8 10.7 6.6 0.0 12.7 7.1 17.7 18.0 19.8 11.9 16.4 16.3 12.5 19.9 10.1 TBC1D22A C22orf4 ENSG00000054611 "TBC1 domain family member 22A" Q8WUA7 22 46762617-47175699 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 252.9;Oligodendrocytes: 113.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001173 Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 52: Non-specific - Ribosome" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 57: B-cells - Immune response" "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA001173: AB_1080212" "unprognostic (1.62e-1)" "unprognostic (5.90e-3)" "unprognostic (1.10e-1)" "unprognostic (4.79e-3)" "unprognostic (3.65e-2)" "unprognostic (7.07e-2)" "prognostic unfavorable (2.42e-4)" "unprognostic (5.95e-2)" "unprognostic (8.17e-2)" "prognostic unfavorable (6.94e-4)" "unprognostic (1.69e-1)" "unprognostic (9.17e-2)" "unprognostic (4.68e-2)" "unprognostic (4.93e-2)" "unprognostic (4.14e-1)" "unprognostic (1.09e-1)" "unprognostic (2.39e-1)" 13.4 12.3 10.5 14.4 9.9 10.4 11.8 9.0 10.5 11.8 7.9 12.5 14.9 10.5 6.8 18.1 12.1 9.3 12.9 10.4 9.2 13.3 11.0 12.7 19.4 11.3 11.5 9.8 14.7 12.0 11.2 12.0 10.7 9.3 9.5 4.9 14.1 7.8 17.9 17.6 15.0 7.6 9.8 19.1 14.8 7.3 11.0 14.7 12.3 11.3 18.4 11.0 12.3 11.4 19.1 13.0 8.1 9.9 11.6 16.1 9.9 12.8 17.2 14.3 15.3 14.8 14.5 16.6 13.9 19.5 8.9 20.7 7.0 20.0 9.9 7.2 19.6 9.5 11.1 28.6 17.7 20.9 7.4 18.9 23.0 9.8 13.6 17.2 23.7 10.4 6.2 17.4 13.1 9.8 9.3 10.7 8.0 17.9 14.6 11.8 9.5 17.9 16.7 9.7 6.6 12.3 11.8 4.5 20.1 10.0 10.5 13.7 19.5 10.9 15.3 11.5 8.2 11.5 3.9 10.5 27.0 10.6 6.9 2.5 10.7 6.3 6.4 15.5 6.0 11.6 5.9 6.1 12.5 13.0 3.9 4.3 15.5 5.5 18.6 6.1 10.2 6.6 10.5 9.9 9.0 10.5 10.4 9.2 11.3 11.5 10.7 9.8 11.0 11.4 20.3 25.6 18.3 81.0 47.0 6.4 12.1 21.1 21.6 18.6 9.9 7.9 8.6 14.3 20.2 7.3 18.8 24.4 22.7 27.9 11.7 25.8 13.9 20.1 14.2 19.0 3.6 13.5 82.0 23.5 19.6 12.2 39.3 14.5 17.1 13.3 23.2 7.9 33.1 21.9 94.2 16.2 18.3 23.0 16.7 3.5 9.9 32.7 10.6 252.9 39.4 13.7 29.9 76.9 113.2 30.2 25.2 11.7 28.8 10.5 39.4 19.8 15.0 27.3 13.1 12.3 11.8 7.9 10.5 18.5 8.0 29.0 22.7 12.7 18.4 11.8 TBC1D3 "DKFZp434P2235, PRC17, TBC1D3A" ENSG00000274611 "TBC1 domain family member 3" Q8IZP1 17 38181659-38192541 "Predicted membrane proteins" "GTPase activation" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebral cortex: 5.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.6;REH: 5.0;U-138 MG: 6.6;U-266/70: 10.3;U-266/84: 4.3;U-698: 5.4" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 29: U-266 - Adaptive immune response" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" 0.9 1.9 0.8 0.0 0.9 0.2 0.7 0.8 5.2 1.7 0.8 1.1 0.0 2.3 0.0 2.3 0.7 1.0 0.8 0.9 0.6 1.6 2.0 1.1 1.3 0.9 0.8 1.5 1.2 1.0 2.1 0.0 0.9 2.0 1.4 2.9 1.4 0.1 0.9 2.3 4.1 0.0 0.6 1.5 1.1 3.7 0.8 0.0 1.3 0.0 2.1 1.7 1.8 0.7 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 6.6 0.0 0.0 0.0 10.3 4.3 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.8 5.2 0.9 0.6 0.9 0.8 0.9 0.6 0.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBC1D3B "PRC17, TBC1D3I" ENSG00000274808 "TBC1 domain family member 3B" A6NDS4 17 36165681-36176636 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 13.8" "Cell type enriched" "Detected in some" 12 "Early spermatids: 20.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 8.6;HeLa: 8.7;T-47d: 5.9" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" "unprognostic (1.05e-1)" "unprognostic (3.63e-1)" "unprognostic (1.94e-2)" "unprognostic (1.49e-1)" "unprognostic (1.67e-1)" "unprognostic (4.13e-2)" "unprognostic (1.11e-1)" "unprognostic (2.83e-1)" "unprognostic (2.51e-1)" "unprognostic (1.17e-1)" "unprognostic (7.15e-2)" "unprognostic (9.96e-3)" "unprognostic (1.05e-3)" "unprognostic (1.46e-1)" "unprognostic (1.32e-1)" "unprognostic (3.56e-1)" "unprognostic (1.34e-1)" 2.4 4.0 3.6 1.3 2.9 0.9 2.5 4.2 4.0 3.7 1.9 3.6 1.4 2.2 0.2 5.8 3.2 0.6 2.1 4.8 3.0 3.6 4.2 3.1 1.0 4.6 2.2 4.0 3.6 0.4 5.0 0.5 5.8 5.0 0.5 2.4 4.3 1.0 3.7 6.0 4.3 0.5 1.0 4.9 3.1 13.8 3.9 0.8 3.2 0.3 0.6 4.2 5.0 1.3 1.1 1.8 1.1 1.3 1.1 1.3 3.6 0.9 0.5 1.0 1.5 0.4 8.6 0.2 0.7 0.5 0.4 3.8 0.5 0.8 0.3 1.5 2.8 0.6 8.7 0.5 0.6 0.2 1.0 1.1 1.7 1.1 0.2 2.4 0.7 0.9 0.5 0.8 0.3 0.1 0.8 3.4 0.4 0.3 0.4 1.1 0.3 0.1 1.1 1.1 0.7 0.9 0.8 0.5 0.6 1.4 5.9 0.8 2.0 0.4 0.3 2.9 0.4 1.2 1.0 0.4 1.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.6 2.9 4.2 4.0 4.8 3.0 4.6 2.2 5.8 1.0 3.9 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 TBC1D3C MGC44903 ENSG00000278299 "TBC1 domain family member 3C" Q6IPX1 17 38057693-38068592 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 7.0" "Cell type enriched" "Detected in single" 9 "Early spermatids: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "CAPAN-2: 34.4" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 43: Testis - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" 1.1 1.5 1.5 0.4 1.7 1.8 1.2 1.9 2.7 1.1 1.7 1.3 0.5 2.1 0.0 2.2 2.3 0.7 0.9 1.6 1.6 4.0 2.1 1.3 0.7 2.0 1.4 1.8 1.6 0.0 1.9 0.2 2.0 2.5 0.0 1.5 1.7 0.1 1.3 2.2 2.1 0.2 0.8 2.3 1.3 7.0 1.5 1.5 1.2 0.0 0.6 1.6 2.1 1.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.4 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.1 7.7 0.1 1.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.8 0.0 1.0 0.1 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.6 0.3 0.0 1.2 0.0 0.0 3.3 6.9 3.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.7 1.9 2.7 1.6 1.6 2.0 1.4 2.0 0.8 1.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBC1D3D ENSG00000274419 "TBC1 domain family member 3D" A0A087WVF3 17 38003976-38014902 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.8;Cholangiocytes: 2.8;Cone photoreceptor cells: 6.2;Pancreatic endocrine cells: 4.1;Rod photoreceptor cells: 1.9;Syncytiotrophoblasts: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.7;HaCaT: 7.0;HeLa: 9.6;RPMI-8226: 4.2;RT4: 4.9" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 71: Testis - DNA repair" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" 1.7 3.2 0.6 0.0 0.6 0.0 1.7 1.1 3.7 2.5 0.6 2.4 1.4 1.6 0.1 4.1 2.0 0.2 1.5 0.7 0.4 2.5 3.4 2.2 0.3 0.8 0.4 3.0 2.7 0.4 3.2 0.7 0.7 4.1 0.7 2.3 3.2 0.0 2.0 3.9 4.7 0.1 0.5 4.2 2.4 7.3 0.5 0.0 2.1 0.0 0.5 3.5 3.4 0.7 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.9 7.0 0.0 0.0 0.0 0.0 0.0 1.8 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.0 4.2 0.0 4.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 2.4 0.9 0.0 2.9 1.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 1.1 3.7 0.7 0.4 0.8 0.4 0.7 0.5 0.5 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.8 2.8 1.3 0.0 6.2 0.8 0.1 0.0 0.0 1.0 0.6 0.5 0.1 0.4 0.0 0.0 0.0 1.7 0.3 0.4 0.0 0.8 0.0 0.0 0.7 0.6 0.7 0.0 0.0 0.0 0.0 1.3 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.3 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 TBC1D3E ENSG00000278599 "TBC1 domain family member 3E" A0A087X179 17 38127951-38138862 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "HHSteC: 4.1;HL-60: 1.0" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" "unprognostic (1.18e-1)" "unprognostic (3.35e-1)" "unprognostic (3.51e-1)" "unprognostic (4.22e-2)" "unprognostic (6.28e-2)" "unprognostic (1.87e-2)" "unprognostic (5.07e-3)" "unprognostic (1.32e-3)" 0.4 0.8 0.0 0.0 0.0 1.6 0.3 0.0 0.1 0.0 0.0 0.4 0.0 0.3 0.0 1.1 0.3 1.2 0.4 0.0 0.0 2.8 0.9 0.6 0.7 0.2 0.0 0.6 1.7 0.0 0.7 0.0 0.3 1.3 0.0 0.3 0.5 0.0 0.4 1.0 0.8 0.0 0.0 1.1 0.5 3.3 0.0 0.0 0.5 0.0 0.0 0.1 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 4.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBC1D3F ENSG00000275954 "TBC1 domain family member 3F" 17 36428618-36439566 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 6.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046969 Uncertain Vesicles NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" Vesicles "HPA046969: " 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.2 0.3 0.2 0.0 0.0 0.3 0.1 6.8 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBC1D3G ENSG00000260287 "TBC1 domain family member 3G" Q6DHY5 17 36323884-36334759 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 26.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SiHa: 1.3" "HPA046969, HPA047745, HPA052553" Supported Approved Vesicles NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" "unprognostic (4.41e-1)" "unprognostic (1.17e-2)" "unprognostic (5.01e-2)" 0.4 0.8 0.2 0.0 0.2 0.0 0.5 0.2 0.9 0.8 0.2 0.5 0.1 0.9 0.0 1.2 1.5 0.0 0.5 0.2 0.2 2.8 1.2 0.6 0.0 0.2 0.2 0.9 0.6 0.0 0.9 0.0 0.2 1.4 0.0 0.0 0.6 0.0 0.5 1.0 0.6 0.0 0.2 1.5 0.4 26.1 0.2 0.0 0.4 0.0 0.0 1.2 0.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.9 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBC1D3H ENSG00000274226 "TBC1 domain family member 3H" P0C7X1 17 36377531-36388423 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "CAPAN-2: 5.9" "HPA046969, HPA047745, HPA052553" Approved Approved Vesicles NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" 0.1 0.3 1.3 0.0 1.3 0.1 0.1 1.3 1.5 0.6 1.3 0.2 0.0 0.0 0.0 0.6 0.6 0.0 0.2 1.3 1.3 1.1 0.5 0.3 0.0 1.3 1.3 0.2 0.0 0.0 0.5 0.0 1.4 0.6 0.0 0.1 0.2 0.0 0.1 0.4 0.3 0.0 1.3 0.6 0.1 4.7 1.3 0.0 0.2 0.0 0.0 0.5 0.5 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.3 1.3 1.5 1.3 1.3 1.3 1.3 1.4 1.3 1.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBC1D3I ENSG00000274933 "TBC1 domain family member 3I" A0A087WXS9 17 36253456-36264553 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 7.0" "Cell type enriched" "Detected in some" 12 "Early spermatids: 38.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "CAPAN-2: 5.3" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" 0.1 0.1 0.8 0.0 1.0 0.0 0.1 1.1 1.5 0.3 0.7 0.1 0.0 0.1 0.0 0.3 0.3 0.0 0.2 1.0 1.0 0.2 0.3 0.1 0.1 1.0 0.8 0.2 0.2 0.0 0.3 0.0 1.0 0.3 0.0 0.0 0.1 0.1 0.1 0.2 0.2 0.0 0.6 0.3 0.1 7.0 0.9 0.0 0.1 0.0 0.0 0.2 0.2 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 5.3 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.4 0.3 0.2 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.0 1.1 1.5 1.0 1.0 1.0 0.8 1.0 0.6 0.9 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBC1D3K ENSG00000273513 "TBC1 domain family member 3K" A0A087X1G2 17 37924415-37935365 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 2.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "T-47d: 1.4" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 71: Testis - DNA repair" "Cluster 6: T47d - Mammary gland" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.6 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.2 0.3 0.2 0.3 0.0 0.0 0.5 0.2 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.3 0.3 0.2 0.0 0.0 0.2 0.1 2.2 0.1 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TBC1D3L ENSG00000274512 "TBC1 domain family member 3L" B9A6J9 17 37977972-37989048 "Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Early spermatids: 5.0;Gastric mucus-secreting cells: 5.1;Glandular and luminal cells: 2.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 39.1;hTERT-RPE1: 42.8;NB-4: 38.0" "HPA046969, HPA047745, HPA052553" Approved Uncertain Vesicles NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 44: Endometrium - Transcription" Vesicles "HPA046969: , HPA047745: AB_2680144, HPA052553: AB_2681869" "unprognostic (5.14e-2)" "unprognostic (8.71e-2)" "unprognostic (8.44e-2)" "unprognostic (1.28e-1)" "unprognostic (3.61e-2)" "unprognostic (6.34e-2)" "unprognostic (3.19e-1)" "unprognostic (9.50e-2)" "unprognostic (1.76e-1)" "unprognostic (1.04e-1)" "unprognostic (1.80e-2)" "unprognostic (6.63e-6)" "unprognostic (2.90e-1)" "unprognostic (2.21e-1)" "unprognostic (1.66e-1)" "unprognostic (1.28e-3)" 12.9 26.7 9.5 9.7 8.8 5.7 12.3 12.6 25.1 23.0 10.8 18.2 10.9 9.8 11.4 33.8 19.1 6.1 12.6 9.3 7.6 22.9 29.8 17.8 10.1 8.8 7.5 17.4 17.6 3.5 29.0 4.7 9.2 31.0 6.6 46.9 19.8 7.2 17.5 36.3 20.3 4.4 6.4 30.3 17.0 26.1 8.5 9.8 16.4 7.6 4.8 20.6 28.0 11.8 12.8 16.7 6.6 10.0 12.3 11.1 39.1 5.7 3.8 5.1 5.9 9.3 0.2 4.3 0.2 7.3 4.5 20.5 6.1 5.4 3.4 12.6 15.5 0.0 31.9 4.0 8.6 1.7 15.4 9.4 13.0 6.6 3.7 42.8 7.0 8.0 3.4 14.6 8.4 6.8 7.6 38.0 6.3 9.6 3.7 5.0 7.7 0.0 16.1 17.2 9.0 12.5 0.0 6.6 7.7 15.3 9.6 2.7 15.7 0.0 8.6 6.7 8.0 10.2 4.8 0.0 10.2 5.3 5.8 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.2 1.0 0.2 0.2 0.0 0.1 0.1 9.5 8.8 12.6 25.1 9.3 7.6 8.8 7.5 9.2 6.4 8.5 11.8 0.2 0.0 0.0 1.0 0.4 0.0 0.0 0.0 1.2 0.0 0.6 0.9 0.1 0.0 0.0 1.8 0.0 0.1 0.3 0.2 0.0 0.4 5.0 1.1 0.9 0.2 0.0 0.0 1.1 0.0 0.1 0.3 5.1 2.2 0.0 0.9 0.0 0.3 0.1 0.0 1.0 0.3 0.0 0.3 0.0 0.6 0.3 0.4 0.0 1.9 0.0 0.0 0.0 0.5 0.1 0.5 1.3 0.0 0.7 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.2 0.6 0.3 0.7 0.0 0.3 0.6 0.4 0.5 0.0 TBC1D5 KIAA0210 ENSG00000131374 "TBC1 domain family member 5" Q92609 3 17157162-18444817 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autophagy, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Astrocytes: 226.6;Excitatory neurons: 333.2;Inhibitory neurons: 350.5;Microglial cells: 324.2;Oligodendrocyte precursor cells: 341.8;Oligodendrocytes: 565.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035125, HPA035126" Uncertain Supported "Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "Golgi apparatus" "HPA035125: AB_2674479, HPA035126: AB_10670696" "unprognostic (1.87e-1)" "unprognostic (3.57e-1)" "unprognostic (2.86e-2)" "unprognostic (3.19e-1)" "unprognostic (1.60e-1)" "unprognostic (4.30e-3)" "unprognostic (3.07e-2)" "unprognostic (3.31e-1)" "unprognostic (3.56e-2)" "unprognostic (6.27e-2)" "unprognostic (2.05e-1)" "unprognostic (1.42e-1)" "prognostic favorable (1.75e-7)" "unprognostic (1.25e-1)" "unprognostic (1.56e-1)" "unprognostic (5.72e-2)" "unprognostic (7.07e-2)" 17.9 17.4 13.7 17.0 21.1 25.2 18.6 18.2 15.5 20.1 6.0 13.5 10.8 17.6 12.1 16.8 22.5 19.2 15.8 13.8 16.1 19.9 14.7 18.0 23.1 21.9 17.7 28.1 18.3 25.7 8.5 17.5 22.8 14.0 13.9 10.9 14.1 16.4 9.3 14.0 13.8 18.3 18.3 24.0 13.8 18.9 16.0 20.3 30.0 11.3 23.2 14.8 10.1 29.9 26.3 28.8 23.2 22.0 45.0 65.5 25.4 27.6 39.7 17.7 15.3 14.0 23.2 48.5 29.1 56.3 27.1 8.0 20.6 33.6 36.6 43.0 7.9 46.6 11.1 16.5 28.8 45.7 39.0 42.6 39.3 38.5 23.2 39.8 40.9 28.3 29.6 43.6 43.5 17.6 22.5 10.5 19.1 16.8 30.0 48.9 29.6 34.7 26.3 20.0 8.8 41.0 52.5 12.2 18.6 21.7 34.6 37.6 44.7 48.7 21.6 25.6 30.4 25.2 36.6 46.7 37.5 42.3 46.5 11.7 8.1 11.9 5.8 6.5 7.5 10.3 4.4 4.2 9.2 11.3 3.2 3.8 10.4 4.3 6.3 5.8 5.2 4.8 13.7 21.1 18.2 15.5 13.8 16.1 21.9 17.7 22.8 18.3 16.0 29.9 40.4 16.0 35.0 226.6 56.0 18.4 20.0 15.8 42.7 20.3 23.0 19.9 18.6 25.8 27.8 14.7 10.4 17.1 28.9 9.2 5.9 17.7 64.1 19.6 28.9 30.7 13.1 31.3 333.2 9.9 16.7 32.5 20.4 28.2 18.9 31.5 34.6 19.9 21.4 35.3 350.5 13.4 10.2 35.6 22.9 40.2 30.7 34.9 14.2 324.2 23.2 26.6 32.0 341.8 565.6 12.3 9.1 30.5 20.7 9.8 13.7 15.9 16.3 22.3 6.6 34.0 20.4 20.7 25.5 28.4 17.0 8.2 30.0 35.5 14.5 17.6 TBK1 NAK ENSG00000183735 "TANK binding kinase 1" Q9UHD2 12 64452090-64502114 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Amyotrophic lateral sclerosis, Disease variant, Glaucoma, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045797, HPA060211" Uncertain Enhanced Nucleoplasm,Vesicles NA NA "Cluster 34: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm Vesicles "HPA045797: AB_2679457, HPA060211: AB_2684222" "unprognostic (4.73e-2)" "unprognostic (8.46e-2)" "unprognostic (6.07e-3)" "unprognostic (1.90e-1)" "unprognostic (1.94e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (3.30e-4)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.48e-4)" "unprognostic (1.69e-1)" "unprognostic (2.54e-2)" "unprognostic (1.24e-2)" "prognostic unfavorable (4.20e-6)" "unprognostic (4.35e-2)" "unprognostic (1.30e-1)" "unprognostic (1.26e-2)" "unprognostic (9.56e-3)" 11.6 15.3 6.0 10.1 6.1 16.9 11.4 5.6 6.9 10.6 5.3 10.5 15.1 11.0 6.7 11.3 9.5 10.1 9.4 5.8 5.6 11.8 17.4 12.9 14.6 6.5 6.9 9.6 7.5 11.6 9.8 13.7 6.1 10.6 8.5 6.3 10.2 9.0 18.4 8.6 11.4 10.8 5.3 13.4 10.2 23.5 6.7 6.8 8.5 14.9 12.9 16.0 10.2 7.1 23.3 24.2 11.1 10.6 24.7 26.1 29.0 22.9 37.6 22.5 21.1 14.9 12.4 31.5 21.4 26.8 34.4 19.0 19.4 20.0 26.4 29.5 17.1 33.0 15.3 19.1 30.2 35.2 36.4 18.5 19.1 23.1 23.6 42.3 32.4 11.0 27.9 38.7 31.6 27.0 0.9 17.0 29.9 22.9 13.8 14.9 15.3 31.8 25.1 36.9 9.8 14.7 33.3 36.0 23.5 23.5 33.1 24.9 25.9 20.2 18.1 14.9 24.0 25.4 54.3 30.3 28.1 18.6 26.1 41.8 10.1 24.3 13.9 17.7 16.3 12.8 10.1 15.2 12.2 10.1 2.8 8.7 17.8 26.6 15.5 2.1 13.6 10.0 6.0 6.1 5.6 6.9 5.8 5.6 6.5 6.9 6.1 5.3 6.7 7.1 23.7 19.2 20.5 28.4 21.6 11.0 25.7 20.1 15.4 17.0 14.9 9.1 10.9 8.6 23.4 22.0 10.4 28.8 30.0 14.1 11.7 19.3 34.5 19.2 17.9 28.6 17.3 18.3 50.5 23.6 32.6 21.3 15.3 30.2 43.1 17.5 16.8 17.1 20.2 18.5 42.2 10.5 12.2 23.0 30.2 29.2 19.3 31.1 14.2 46.9 31.4 12.7 33.0 39.2 52.3 16.9 10.9 20.7 25.6 43.7 13.6 12.3 20.8 16.3 26.3 22.4 18.7 68.9 12.7 14.0 14.9 92.6 27.1 11.5 10.1 41.6 TBX4 ENSG00000121075 "T-box transcription factor 4" P57082 17 61452404-61485110 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lung: 32.3;placenta: 21.0;prostate: 9.0" "Group enriched" "Detected in some" 8 "Early spermatids: 6.2;Late spermatids: 14.6" "Cancer enhanced" "Detected in some" "lung cancer: 2.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 2.9;Hep G2: 1.2;OE19: 1.2;THP-1: 5.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB032413, HPA044457" Uncertain Approved Vesicles NA NA "Cluster 19: Lung - Lung function" "Cluster 43: THP-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "CAB032413: AB_2200705, HPA044457: AB_2678948" "unprognostic (1.03e-2)" "unprognostic (2.05e-2)" "unprognostic (1.43e-1)" "unprognostic (1.63e-3)" "unprognostic (6.07e-2)" "unprognostic (3.80e-2)" "unprognostic (1.25e-2)" "unprognostic (4.14e-2)" "unprognostic (7.77e-3)" "unprognostic (7.41e-2)" "unprognostic (6.83e-2)" "unprognostic (1.38e-1)" "unprognostic (1.46e-8)" "unprognostic (1.92e-1)" "unprognostic (4.41e-2)" "unprognostic (6.15e-2)" "unprognostic (5.39e-2)" 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.7 0.0 0.1 0.0 0.2 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 32.3 0.1 0.1 0.1 0.0 0.3 0.0 0.0 21.0 0.1 9.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 7.2 0.4 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 2.9 0.3 0.2 0.2 1.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 1.2 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.3 0.1 0.0 5.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TCAF1 "FAM115A, KIAA0738" ENSG00000198420 "TRPM8 channel associated factor 1" Q9Y4C2 7 143851375-143902198 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 251.7;Syncytiotrophoblasts: 521.5;Theca cells: 377.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011732 Approved Approved "Nuclear bodies,Vesicles,Cell Junctions" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 28: Placenta - Pregnancy" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 52: Non-specific - Transcription" "Cell Junctions" "Nuclear bodies, Vesicles" "HPA011732: AB_2668526" "unprognostic (1.57e-1)" "unprognostic (7.28e-2)" "unprognostic (2.61e-1)" "unprognostic (3.11e-1)" "unprognostic (2.73e-1)" "unprognostic (7.00e-2)" "unprognostic (5.70e-3)" "unprognostic (3.07e-2)" "unprognostic (4.93e-2)" "prognostic favorable (5.93e-4)" "unprognostic (1.43e-1)" "unprognostic (2.69e-1)" "unprognostic (3.95e-3)" "unprognostic (6.45e-2)" "unprognostic (1.34e-1)" "unprognostic (1.55e-2)" "unprognostic (1.89e-1)" 29.0 46.5 22.7 12.9 51.4 4.7 21.7 15.1 30.3 27.5 2.7 18.8 12.2 32.2 15.2 15.1 22.2 19.3 23.7 29.4 42.7 14.8 29.3 19.0 8.4 15.4 13.4 39.9 19.4 35.1 27.2 81.1 19.8 36.2 20.3 28.0 15.8 19.8 17.5 16.9 15.8 30.6 11.5 11.7 21.7 9.4 31.0 17.1 26.8 55.7 9.0 14.8 13.4 20.1 47.2 29.0 90.1 93.7 57.9 55.7 55.1 54.3 64.9 42.4 56.3 60.5 33.0 0.2 25.2 63.3 54.5 29.7 34.8 35.7 46.5 25.7 26.0 25.7 15.7 54.0 39.7 0.3 16.2 58.2 31.5 50.0 18.4 66.8 53.4 32.2 43.2 4.5 83.2 70.7 42.3 15.9 27.6 52.0 17.4 26.0 60.7 6.2 33.7 37.5 25.6 153.1 55.5 34.2 25.7 63.7 51.5 4.0 48.8 44.6 28.5 42.2 32.7 14.0 19.2 0.4 81.9 7.6 62.3 0.4 1.5 0.9 4.7 1.8 3.3 1.6 2.8 3.1 2.9 1.6 2.4 3.0 0.4 4.4 3.1 1.4 2.3 2.5 22.7 51.4 15.1 30.3 29.4 42.7 15.4 13.4 19.8 11.5 31.0 20.1 36.3 44.8 37.1 30.3 7.3 0.0 15.0 0.0 16.5 47.7 29.4 38.6 43.0 31.5 14.9 3.7 25.0 251.7 15.2 18.7 0.0 30.9 2.4 27.6 62.7 35.1 19.4 22.1 71.2 35.6 43.7 54.6 20.9 40.5 7.6 167.5 34.6 83.6 32.9 30.3 63.1 29.3 0.0 10.5 0.0 3.5 53.1 12.2 0.0 29.0 10.8 27.5 20.6 57.3 43.7 49.9 15.4 56.4 8.4 27.3 20.1 8.9 8.0 26.7 13.1 72.1 53.3 13.3 11.7 14.1 0.0 521.5 10.4 377.5 23.5 24.3 TCEA3 TFIIS.H ENSG00000204219 "Transcription elongation factor A3" O75764 1 23380909-23424748 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 513.3" "Cell type enhanced" "Detected in many" "Granulosa cells: 214.8;Hepatocytes: 205.9;Intestinal goblet cells: 376.2;Proximal tubular cells: 260.9;Undifferentiated cells: 223.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD4 T-cell: 8.4;naive CD4 T-cell: 13.6" "Lineage enriched" "Detected in many" 5 "T-cells: 13.6" "Cell line enhanced" "Detected in many" "ASC TERT1: 15.3;Hep G2: 55.1;OE19: 28.7;SiHa: 18.2;T-47d: 28.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA044960, HPA055811" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA044960: AB_10964053, HPA055811: AB_2682932" "unprognostic (1.58e-1)" "unprognostic (1.75e-3)" "unprognostic (9.18e-2)" "unprognostic (3.82e-2)" "unprognostic (2.77e-3)" "prognostic favorable (2.56e-4)" "unprognostic (2.86e-2)" "unprognostic (4.70e-3)" "unprognostic (7.37e-3)" "unprognostic (2.85e-1)" "unprognostic (2.22e-2)" "unprognostic (3.27e-1)" "unprognostic (2.23e-1)" "unprognostic (4.01e-1)" "unprognostic (5.20e-2)" "unprognostic (3.15e-1)" "unprognostic (5.58e-2)" 17.5 95.6 4.7 4.6 4.3 0.6 19.6 4.1 4.7 35.7 7.8 87.1 15.8 17.0 7.3 40.5 28.3 11.6 71.6 4.0 4.4 64.9 160.7 20.4 2.4 6.0 4.9 81.9 229.4 16.3 14.9 3.9 5.4 59.9 39.8 3.2 100.3 14.5 513.3 53.4 35.2 9.2 5.2 10.6 75.9 4.7 4.1 1.8 41.2 173.1 4.5 36.2 38.7 5.1 0.0 0.1 0.5 0.5 2.5 15.3 9.0 6.4 4.1 3.2 1.9 4.1 0.5 0.2 0.7 7.9 1.0 9.1 0.5 0.1 2.8 0.0 0.1 0.0 6.9 55.1 1.9 0.8 0.0 10.1 2.8 2.9 0.0 7.1 0.4 0.1 0.0 0.0 1.1 1.5 0.4 6.1 0.0 28.7 1.8 0.1 0.0 0.2 0.0 0.1 0.5 0.1 18.2 0.8 0.8 1.5 28.4 2.8 0.4 0.0 0.2 0.7 0.0 0.5 5.3 0.0 0.5 0.5 0.6 0.0 0.2 0.0 0.4 0.7 0.4 0.0 8.4 1.1 2.9 0.0 13.6 6.1 0.0 0.2 0.2 0.9 0.8 2.3 4.7 4.3 4.1 4.7 4.0 4.4 6.0 4.9 5.4 5.2 4.1 5.1 10.5 125.0 109.5 4.2 1.9 27.4 53.4 30.9 30.7 2.3 46.3 42.4 109.8 100.1 57.2 42.3 2.1 3.3 1.9 158.0 199.6 37.7 6.1 7.7 6.6 13.4 55.9 5.7 2.8 97.9 33.9 45.2 69.3 20.8 9.5 214.8 8.2 205.9 1.5 25.2 4.5 376.2 6.1 7.6 65.4 17.9 17.1 8.4 24.9 3.7 3.2 6.8 3.1 2.0 1.3 25.5 143.0 15.4 0.5 38.8 154.3 260.9 29.4 1.4 19.7 90.1 24.0 0.7 2.6 61.1 54.8 2.2 8.4 52.0 223.5 73.9 TCEANC2 "C1orf83, FLJ32112" ENSG00000116205 "Transcription elongation factor A N-terminal and central domain containing 2" Q96MN5 1 54053584-54112519 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 36.4;Spermatocytes: 29.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046918 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 42: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm Vesicles "HPA046918: AB_2679864" "unprognostic (2.80e-1)" "unprognostic (6.19e-2)" "unprognostic (6.56e-3)" "unprognostic (2.34e-1)" "unprognostic (5.12e-3)" "unprognostic (1.35e-3)" "unprognostic (1.73e-5)" "unprognostic (8.64e-2)" "unprognostic (7.93e-3)" "unprognostic (6.59e-2)" "unprognostic (3.55e-1)" "unprognostic (3.52e-2)" "unprognostic (9.63e-2)" "unprognostic (2.26e-3)" "unprognostic (8.57e-2)" "unprognostic (7.51e-3)" "unprognostic (2.08e-1)" 2.0 2.3 5.8 2.9 5.6 2.8 2.2 4.7 5.8 2.2 4.9 2.6 2.6 2.1 2.3 2.9 2.1 1.5 2.6 5.0 5.1 2.4 2.2 1.9 3.9 5.7 5.5 1.8 2.1 2.3 2.1 2.3 5.7 2.3 3.1 2.1 2.0 1.5 3.8 2.5 2.6 1.8 5.5 3.7 2.4 7.1 6.1 5.1 2.1 3.1 3.7 2.7 2.3 6.6 4.3 1.9 4.6 3.9 3.3 5.2 4.9 4.5 3.6 4.8 4.2 1.2 2.6 3.2 3.8 1.6 4.4 4.1 6.6 3.6 6.5 7.6 2.7 6.3 4.3 2.0 1.9 4.2 5.3 3.7 3.0 4.0 2.4 2.4 7.1 8.6 5.7 3.4 4.3 1.6 9.3 3.4 11.4 4.4 2.9 9.2 9.4 5.6 1.6 2.8 4.2 4.4 2.4 4.8 5.8 7.2 4.6 7.6 4.1 4.9 2.7 4.6 5.5 8.1 12.9 5.2 4.1 5.9 6.0 3.3 3.2 4.2 1.6 4.0 1.9 2.8 2.2 2.5 3.5 3.3 2.5 2.9 3.5 4.8 3.4 3.0 1.7 1.5 5.8 5.6 4.7 5.8 5.0 5.1 5.7 5.5 5.7 5.5 6.1 6.6 4.0 9.6 11.2 12.7 6.7 0.6 1.5 2.3 1.2 3.2 3.8 3.0 8.4 5.7 5.9 11.0 12.5 6.1 4.7 2.7 1.9 4.0 36.4 9.8 4.7 5.5 3.6 7.6 6.3 1.8 5.7 3.6 5.6 3.7 2.5 4.4 3.9 4.4 4.8 8.4 7.8 4.2 2.0 9.6 1.0 23.5 3.1 5.3 1.8 6.5 12.3 2.5 9.2 5.5 16.7 3.6 3.7 3.0 5.7 2.4 4.3 3.5 16.8 3.3 0.0 4.2 3.6 29.4 12.5 5.5 1.0 4.0 5.6 4.2 4.5 1.6 TCTE1 "D6S46, DRC5, FAP155, MGC33600" ENSG00000146221 "T-complex-associated-testis-expressed 1" Q5JU00 6 44278734-44297698 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 14.4;testis: 30.0" "Group enriched" "Detected in some" 10 "Early spermatids: 161.8;Late spermatids: 359.0" "Cancer enhanced" "Detected in some" "endometrial cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 1.0;U-266/84: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031739 Uncertain Vesicles NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA031739: AB_10601269" "unprognostic (3.27e-2)" "unprognostic (1.86e-1)" "unprognostic (2.04e-2)" "unprognostic (5.27e-3)" "unprognostic (1.55e-1)" "unprognostic (1.57e-2)" "unprognostic (7.06e-2)" "unprognostic (1.42e-2)" "unprognostic (3.46e-1)" "unprognostic (3.49e-2)" "unprognostic (1.17e-2)" "unprognostic (7.05e-2)" "unprognostic (2.23e-5)" "unprognostic (7.68e-2)" "unprognostic (3.13e-2)" "unprognostic (1.37e-3)" "unprognostic (2.68e-1)" 0.2 0.2 1.4 0.0 1.3 0.9 0.2 6.2 1.3 0.9 1.3 0.2 0.0 0.4 0.2 0.1 14.4 0.1 0.1 1.4 1.0 0.1 0.1 1.4 0.0 3.0 3.3 0.5 0.1 0.0 0.5 1.9 1.5 0.2 0.1 1.0 0.2 0.1 0.1 0.5 0.2 0.1 2.6 0.2 0.1 30.0 1.2 0.1 0.1 0.2 0.0 0.1 0.2 1.0 0.0 0.0 0.0 0.0 0.2 0.3 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.4 0.0 0.0 0.7 0.1 0.1 0.1 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.5 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.3 6.2 1.3 1.4 1.0 3.0 3.3 1.5 2.6 1.2 1.0 0.1 0.0 0.0 1.0 0.0 0.1 0.1 0.7 0.0 1.1 0.1 0.1 0.5 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 161.8 7.3 0.3 0.1 0.0 0.0 1.3 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.3 359.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.0 0.0 0.7 0.0 0.0 0.1 0.0 16.0 0.2 0.0 0.4 0.3 23.9 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 TCTN1 "FLJ21127, JBTS13, TECT1" ENSG00000204852 "Tectonic family member 1" Q2MV58 12 110614027-110663431 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 98.9;Respiratory ciliated cells: 203.7;Spermatocytes: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 34.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039687, HPA040036" Approved Approved "Nucleoplasm,Vesicles,Actin filaments,Microtubules" "Intracellular and membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Actin filaments" "Nucleoplasm, Vesicles, Microtubules" "HPA039687: AB_10795293, HPA040036: AB_10794759" "unprognostic (2.54e-1)" "unprognostic (7.22e-3)" "unprognostic (2.28e-1)" "prognostic favorable (1.13e-5)" "unprognostic (2.89e-2)" "unprognostic (6.53e-2)" "unprognostic (2.11e-1)" "unprognostic (3.05e-2)" "unprognostic (6.02e-2)" "unprognostic (4.54e-2)" "unprognostic (5.20e-3)" "unprognostic (9.60e-2)" "unprognostic (9.97e-2)" "unprognostic (2.15e-2)" "unprognostic (8.41e-2)" "unprognostic (1.24e-1)" "unprognostic (4.27e-2)" 8.8 14.0 5.6 2.0 5.3 1.0 8.4 9.3 7.5 10.1 18.2 7.1 1.5 9.0 10.7 4.5 15.3 5.6 17.0 5.7 4.5 19.0 9.1 8.3 2.5 4.5 5.0 12.8 10.8 15.2 26.2 4.0 4.4 10.0 0.9 3.0 9.5 6.1 10.3 5.3 4.0 3.6 3.6 4.6 6.9 21.1 5.2 1.3 17.6 1.9 0.8 7.7 7.0 7.0 11.6 11.7 6.7 17.6 24.9 18.0 4.3 6.3 16.2 5.9 4.4 1.2 2.7 2.0 6.9 18.6 7.2 6.1 4.7 4.6 5.0 4.7 8.7 0.3 4.1 3.6 8.6 1.2 1.3 14.8 7.8 7.7 7.9 34.7 3.3 3.0 7.4 2.5 9.7 9.4 0.9 2.2 4.1 3.5 16.7 2.4 2.9 14.6 16.8 1.8 5.5 11.7 13.1 1.6 5.3 5.5 22.7 16.0 4.0 8.2 2.4 3.5 6.0 4.2 2.6 2.6 11.1 1.3 9.3 0.0 2.0 0.0 0.8 3.6 2.2 4.9 1.5 2.5 3.4 9.1 2.2 1.6 6.4 1.0 1.9 4.3 0.5 2.0 5.6 5.3 9.3 7.5 5.7 4.5 4.5 5.0 4.4 3.6 5.2 7.0 6.5 3.2 18.8 25.5 24.0 13.8 28.4 38.4 18.2 10.7 22.8 19.3 13.0 24.3 26.0 16.5 31.3 30.9 5.8 1.0 9.8 24.3 82.7 98.9 29.0 11.5 18.0 1.3 15.0 4.7 8.5 30.5 8.2 9.8 3.8 27.1 9.3 6.9 11.8 3.3 12.1 4.8 32.6 3.8 12.4 18.7 17.1 7.0 23.2 7.5 1.7 30.5 0.0 12.5 9.3 4.2 2.4 28.6 9.6 20.0 0.4 42.5 203.7 34.1 6.6 16.2 18.3 96.9 30.1 8.5 11.2 18.3 4.2 38.1 4.7 16.6 TCTN2 "C12orf38, FLJ12975, JBTS24, MKS8, TECT2" ENSG00000168778 "Tectonic family member 2" Q96GX1 12 123671110-123708399 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 27.6;Respiratory ciliated cells: 32.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039900 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Golgi apparatus, Vesicles" "HPA039900: AB_10673366" "unprognostic (3.46e-2)" "unprognostic (1.03e-1)" "unprognostic (1.30e-2)" "unprognostic (1.45e-2)" "unprognostic (1.63e-3)" "unprognostic (1.32e-1)" "unprognostic (3.09e-3)" "unprognostic (3.14e-2)" "unprognostic (7.05e-2)" "unprognostic (1.09e-1)" "unprognostic (3.97e-3)" "unprognostic (2.23e-1)" "unprognostic (1.69e-1)" "unprognostic (2.79e-1)" "unprognostic (2.46e-1)" "unprognostic (7.86e-2)" "unprognostic (2.68e-1)" 5.3 4.4 5.5 2.6 6.4 1.9 7.2 5.8 5.3 10.0 30.4 5.7 2.1 11.0 11.0 3.4 28.5 6.4 4.8 4.9 9.5 10.0 1.4 8.3 3.3 8.4 11.5 14.7 6.9 14.1 16.3 4.6 6.5 9.6 4.0 17.6 9.1 8.6 1.7 8.3 3.8 6.0 7.1 4.1 5.4 11.1 8.7 2.5 12.4 2.1 3.0 5.2 6.7 4.1 14.9 15.1 10.7 15.6 15.0 16.5 13.1 5.4 10.9 11.5 8.7 7.9 14.5 0.5 9.2 8.9 10.0 19.6 6.2 4.9 11.2 2.5 7.6 1.2 10.6 7.2 5.0 3.7 4.8 8.0 8.8 16.3 4.8 34.9 15.7 5.1 7.1 0.3 7.1 7.9 4.5 7.4 6.8 5.9 9.1 4.0 10.8 1.5 13.7 11.1 6.5 8.3 18.2 6.0 8.4 11.0 25.5 5.6 9.8 16.0 8.2 14.7 7.1 4.3 8.9 1.4 20.9 0.4 9.7 1.7 0.2 1.2 1.9 0.6 2.7 1.9 2.2 2.0 0.4 2.1 2.4 2.4 0.3 0.8 0.5 2.5 1.4 0.2 5.5 6.4 5.8 5.3 4.9 9.5 8.4 11.5 6.5 7.1 8.7 4.1 2.7 3.2 5.3 6.5 1.8 4.1 2.3 2.6 1.2 4.4 4.8 2.3 3.8 5.7 3.9 7.3 12.5 2.8 2.1 1.2 0.0 2.9 6.1 27.6 5.0 1.7 1.2 2.5 10.4 2.1 3.0 4.6 2.6 4.3 3.8 5.0 2.9 0.4 1.3 0.0 14.4 1.8 2.0 0.3 1.2 2.8 2.5 1.0 5.4 2.8 1.4 4.6 1.0 2.5 1.3 2.0 0.8 4.9 1.1 1.4 0.2 1.9 32.1 14.5 0.0 6.0 2.7 11.5 10.9 0.6 2.3 1.1 2.4 2.3 3.0 1.0 TDGF1 "CR, CR-1, CRIPTO, Cripto-1" ENSG00000241186 "Teratocarcinoma-derived growth factor 1" P13385 3 46574534-46582457 "Predicted intracellular proteins, Predicted secreted proteins" "Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 23.4;lymphoid tissue: 20.9" "Cell type enriched" "Detected in some" 6 "Distal tubular cells: 121.3" "Cancer enriched" "Detected in many" 4 "testis cancer: 27.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 25.7;NTERA-2: 110.6;SuSa: 66.3" "Group enriched" "Detected in many" 5 "cerebellum: 11.2;pons and medulla: 8.7" "Low region specificity" "Detected in single" HPA051928 Uncertain Vesicles,Cytosol "Secreted in other tissues" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 39: Non-specific - Basic cellular processes" Vesicles Cytosol "HPA051928: " "unprognostic (7.84e-3)" "unprognostic (2.00e-2)" "unprognostic (1.30e-2)" "unprognostic (1.17e-2)" "unprognostic (2.80e-2)" "unprognostic (1.14e-1)" "unprognostic (4.01e-2)" "unprognostic (1.93e-1)" "unprognostic (3.61e-1)" "unprognostic (1.72e-2)" "unprognostic (6.77e-2)" "unprognostic (1.74e-1)" "unprognostic (8.76e-3)" "unprognostic (2.01e-1)" "unprognostic (2.10e-2)" "unprognostic (1.75e-2)" "unprognostic (1.05e-1)" 0.4 3.4 2.4 0.5 1.9 0.3 0.3 2.1 4.8 0.7 1.4 2.6 0.7 1.0 2.0 0.1 0.1 0.6 0.6 1.8 1.7 23.4 1.3 0.4 0.4 2.1 1.8 7.7 0.4 0.1 0.1 0.2 2.2 0.4 4.6 0.4 1.0 0.3 1.5 0.3 0.5 1.2 1.7 20.9 2.7 0.5 3.1 15.1 0.8 1.5 0.1 0.2 0.1 1.9 0.1 0.2 0.1 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.4 0.2 0.1 0.1 0.1 0.0 1.8 0.0 0.2 0.0 0.0 25.7 0.2 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.2 110.6 4.0 0.0 0.2 0.2 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.0 66.3 0.1 0.1 1.8 0.2 0.1 0.2 0.1 0.2 0.0 0.0 0.1 0.0 0.2 0.7 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.9 0.3 0.1 0.1 0.0 0.0 2.4 1.9 2.1 4.8 1.8 1.7 2.1 1.8 2.2 1.7 3.1 1.9 0.9 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 5.5 0.0 0.0 0.0 0.9 121.3 0.2 5.0 0.3 0.1 8.2 2.4 0.0 0.0 0.0 0.0 0.3 8.2 0.2 0.0 14.3 0.4 1.4 0.1 0.0 0.0 5.5 0.0 0.0 0.0 1.0 0.3 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.3 0.6 0.0 0.2 0.0 0.1 0.3 0.1 0.3 0.0 0.0 0.0 0.1 17.7 6.1 0.0 TDRD10 DKFZp434M202 ENSG00000163239 "Tudor domain containing 10" Q5VZ19 1 154502219-154548147 "Cancer-related genes, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 55.6" "Group enriched" "Detected in some" 5 "Early spermatids: 61.8;Late spermatids: 89.0;Spermatocytes: 103.7" "Cancer enhanced" "Detected in many" "testis cancer: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 3.0;TIME: 1.4" "Not detected" "Not detected" HPA054327 Approved Vesicles NA NA "Cluster 71: Testis - DNA repair" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA054327: AB_2682452" "unprognostic (1.30e-1)" "unprognostic (6.33e-2)" "unprognostic (1.78e-1)" "unprognostic (5.33e-3)" "unprognostic (9.69e-3)" "unprognostic (5.80e-3)" "unprognostic (2.99e-1)" "unprognostic (5.97e-3)" "unprognostic (2.44e-2)" "unprognostic (2.06e-1)" "unprognostic (1.00e-3)" "unprognostic (1.61e-1)" "unprognostic (1.34e-3)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" "prognostic favorable (8.04e-5)" "unprognostic (1.62e-1)" 11.1 4.5 3.7 0.5 3.7 0.1 6.8 3.1 3.7 5.1 3.3 2.8 0.7 4.2 2.3 2.4 6.5 1.6 7.6 3.3 3.2 3.5 4.5 8.1 0.8 3.2 3.5 10.1 0.9 0.9 2.6 1.7 3.3 3.9 1.3 0.1 1.8 1.2 1.9 2.3 3.5 1.8 3.2 8.9 1.9 55.6 3.7 0.5 11.0 1.4 0.4 3.9 3.6 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 3.7 3.1 3.7 3.3 3.2 3.2 3.5 3.3 3.2 3.7 3.1 10.0 3.2 6.7 4.9 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.5 1.3 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.8 0.0 0.1 8.2 0.0 0.0 0.3 0.0 0.0 2.1 0.0 0.0 1.3 0.7 6.1 0.4 0.4 0.0 0.5 0.0 0.0 4.0 2.1 89.0 2.5 1.0 0.0 6.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.4 103.7 16.5 0.1 0.3 0.0 0.0 0.1 0.0 0.0 TDRD6 "bA446F17.4, CT41.2, NY-CO-45, SPATA36" ENSG00000180113 "Tudor domain containing 6" O60522 6 46687875-46704319 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 30.3" "Group enriched" "Detected in many" 4 "Early spermatids: 224.8;Spermatocytes: 82.7" "Cancer enhanced" "Detected in some" "prostate cancer: 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HeLa: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA075923, HPA077353" Enhanced Approved "Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 21: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "Microtubules, Cytokinetic bridge, Mitotic spindle" Vesicles "HPA075923: , HPA077353: " "unprognostic (2.01e-1)" "unprognostic (7.41e-3)" "unprognostic (7.25e-3)" "unprognostic (3.88e-2)" "unprognostic (3.54e-1)" "unprognostic (4.10e-2)" "unprognostic (1.03e-1)" "unprognostic (4.32e-2)" "unprognostic (7.97e-2)" "unprognostic (2.50e-1)" "unprognostic (2.20e-3)" "unprognostic (2.20e-1)" "unprognostic (2.79e-1)" "unprognostic (2.86e-1)" "unprognostic (2.00e-1)" "unprognostic (2.16e-2)" "unprognostic (4.38e-3)" 0.7 1.7 3.3 3.0 5.1 0.2 0.8 7.8 5.4 1.2 1.8 1.0 0.7 0.9 3.4 0.6 0.8 2.2 1.6 4.1 2.6 2.1 2.5 0.7 4.0 3.9 3.2 1.1 1.1 0.4 3.0 1.6 4.1 2.0 0.3 8.9 1.3 0.6 2.3 3.5 0.7 0.4 2.7 2.5 0.8 30.3 3.7 0.0 5.6 0.1 0.1 1.1 0.8 4.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 5.1 7.8 5.4 4.1 2.6 3.9 3.2 4.1 2.7 3.7 4.0 0.8 9.6 0.5 3.9 0.0 0.5 0.4 0.1 1.2 11.3 0.4 0.8 3.4 0.0 3.8 7.3 6.2 0.0 0.0 0.0 1.9 0.3 224.8 1.0 2.2 1.2 4.2 0.0 13.6 0.2 0.0 1.0 0.0 0.7 0.0 0.4 0.7 3.0 0.1 5.0 14.7 0.3 0.0 0.3 0.0 33.8 4.1 0.5 3.6 6.5 0.0 1.1 0.0 14.6 17.8 0.1 0.0 4.5 0.0 0.6 0.4 0.4 0.2 7.5 13.1 3.0 0.5 82.7 34.7 0.0 1.6 0.0 0.0 1.4 0.5 0.2 TDRP "C8orf42, INM01, TDRP1, TDRP2" ENSG00000180190 "Testis development related protein" Q86YL5 8 489803-545781 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 151.3;Early spermatids: 80.7;Syncytiotrophoblasts: 272.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 56.1;HBEC3-KT: 27.6;hTERT-RPE1: 23.7;SuSa: 27.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008462 Approved Supported Vesicles,Cytosol NA NA 52000 "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Vesicles, Cytosol" "HPA008462: AB_1845777" "unprognostic (1.17e-1)" "unprognostic (1.88e-1)" "unprognostic (5.51e-2)" "prognostic unfavorable (1.52e-4)" "unprognostic (1.98e-1)" "unprognostic (1.06e-1)" "unprognostic (2.13e-1)" "unprognostic (3.72e-3)" "unprognostic (4.13e-2)" "unprognostic (1.08e-1)" "prognostic favorable (9.37e-4)" "unprognostic (1.74e-1)" "unprognostic (3.43e-2)" "unprognostic (5.46e-4)" "unprognostic (2.38e-2)" "unprognostic (2.98e-2)" "unprognostic (1.50e-1)" 8.7 10.4 12.4 2.2 13.6 0.2 8.7 12.8 14.4 13.3 23.0 6.8 2.1 10.0 9.8 3.9 18.5 10.7 4.6 12.5 14.7 26.9 15.9 9.8 4.4 14.2 13.5 19.5 8.9 16.1 16.7 36.4 13.2 14.7 2.6 16.9 6.5 8.6 1.7 3.3 4.9 5.1 12.4 4.0 6.1 14.0 15.5 4.8 24.6 2.6 5.1 9.9 7.7 10.8 9.9 9.8 16.7 0.0 0.0 0.0 56.1 5.6 3.5 5.3 4.6 0.0 0.0 0.0 2.3 1.8 5.3 2.1 0.0 27.6 6.6 0.0 0.7 0.1 0.0 14.8 6.4 0.0 4.1 6.4 21.4 0.0 10.0 23.7 0.8 0.1 1.2 0.0 5.7 0.0 0.1 0.1 20.0 0.0 2.1 0.0 0.0 0.0 17.0 14.5 5.0 8.1 0.0 17.2 4.5 27.4 5.7 0.0 0.3 0.3 1.7 0.0 0.5 0.0 0.0 0.0 1.7 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 13.6 12.8 14.4 12.5 14.7 14.2 13.5 13.2 12.4 15.5 10.8 20.4 22.4 15.4 41.8 1.0 23.5 28.6 7.3 39.3 17.8 15.8 10.8 4.4 12.8 10.5 18.4 2.1 151.3 0.4 0.5 43.0 10.2 80.7 19.5 10.7 21.2 7.8 0.0 33.3 4.8 61.2 12.2 0.5 7.3 0.0 9.7 7.9 21.0 12.7 10.1 39.9 1.6 16.2 1.9 5.8 16.1 7.2 7.4 8.8 53.4 0.2 9.2 0.0 16.6 4.5 2.9 1.0 6.4 2.5 34.3 0.0 20.7 28.4 12.4 19.7 9.0 10.5 21.5 11.0 7.1 7.0 272.1 0.9 1.7 0.7 14.7 TECPR1 "DKFZP434B0335, FLJ23419, FLJ90593, KIAA1358" ENSG00000205356 "Tectonin beta-propeller repeat containing 1" Q7Z6L1 7 98214624-98252232 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "pancreas: 84.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 106.3;Rod photoreceptor cells: 66.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021061 Approved Supported Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "HPA021061: AB_1847687" "unprognostic (8.10e-3)" "unprognostic (7.89e-2)" "unprognostic (9.05e-3)" "unprognostic (5.00e-3)" "unprognostic (2.03e-1)" "unprognostic (1.11e-2)" "unprognostic (2.49e-2)" "unprognostic (1.45e-2)" "unprognostic (1.72e-1)" "unprognostic (1.88e-1)" "prognostic favorable (8.12e-4)" "unprognostic (2.48e-1)" "unprognostic (2.54e-1)" "unprognostic (1.38e-1)" "unprognostic (3.24e-1)" "unprognostic (9.46e-2)" "unprognostic (6.12e-2)" 8.4 7.0 11.7 10.4 12.3 6.1 8.0 6.5 12.5 6.4 4.7 8.5 9.2 6.8 3.0 9.8 6.9 5.7 9.9 12.7 12.9 7.7 9.2 13.3 11.8 11.8 11.2 5.7 84.9 3.1 16.7 8.6 12.7 11.6 5.0 10.2 18.9 3.8 9.1 5.9 10.8 4.7 8.5 18.6 18.3 4.6 11.5 9.5 9.6 5.0 6.7 6.8 6.6 8.2 4.4 6.1 8.4 18.3 7.2 4.3 6.2 9.1 5.0 7.1 8.7 5.8 5.4 3.6 14.4 10.6 8.8 2.8 5.7 4.2 3.0 8.8 8.0 5.3 9.4 5.3 8.5 6.5 9.9 7.5 3.4 6.9 5.3 6.6 25.2 15.1 3.6 15.0 5.4 7.2 9.4 6.8 3.3 8.6 5.9 7.8 8.5 17.7 5.4 4.8 15.0 16.9 5.4 14.9 8.5 6.1 4.8 9.2 26.0 6.7 11.5 17.4 7.6 17.6 9.8 1.9 14.0 5.6 12.5 2.5 2.9 0.9 2.2 3.2 1.3 1.8 2.9 1.7 1.8 1.6 4.8 4.2 3.5 1.0 4.9 2.4 3.0 2.3 11.7 12.3 6.5 12.5 12.7 12.9 11.8 11.2 12.7 8.5 11.5 8.2 32.2 9.6 18.4 18.3 12.3 2.3 2.2 3.7 1.8 37.1 7.0 5.8 11.2 7.2 7.0 5.5 106.3 6.0 10.9 16.0 1.9 6.4 2.1 6.9 5.5 22.9 29.3 2.1 21.1 13.4 9.8 7.2 35.7 8.1 8.2 11.0 21.0 8.5 13.7 32.0 17.8 22.9 10.2 20.5 4.0 2.2 7.2 14.2 1.8 16.9 19.5 11.4 14.4 10.1 10.1 11.9 10.3 3.4 17.4 4.1 10.8 3.6 7.7 66.7 0.0 7.5 7.4 5.5 4.5 7.1 1.8 3.4 16.0 9.0 10.0 2.9 TEP1 "p240, TLP1, TP1, TROVE1, VAULT2" ENSG00000129566 "Telomerase associated protein 1" Q99973 14 20365667-20413501 "Plasma proteins, Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 23.9;Gastric mucus-secreting cells: 25.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029206 Supported Nucleoplasm,Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 21: OE19 - Mitochondria" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm Vesicles "HPA029206: AB_10601271" "unprognostic (4.53e-2)" "unprognostic (2.81e-2)" "unprognostic (1.26e-1)" "prognostic favorable (9.58e-4)" "unprognostic (2.27e-1)" "unprognostic (2.76e-1)" "unprognostic (2.66e-2)" "unprognostic (1.43e-1)" "unprognostic (6.81e-2)" "unprognostic (1.42e-2)" "unprognostic (1.92e-1)" "unprognostic (1.05e-1)" "unprognostic (1.46e-1)" "unprognostic (1.10e-1)" "unprognostic (2.18e-1)" "unprognostic (6.18e-2)" "unprognostic (3.00e-1)" 9.4 7.8 3.4 12.1 4.1 5.1 8.7 3.2 4.0 7.8 6.0 17.4 28.0 6.9 7.3 6.8 7.2 10.7 6.8 3.3 4.3 6.5 6.5 11.0 15.0 6.0 5.3 6.2 6.2 13.7 5.7 6.6 5.1 7.9 17.9 5.0 8.3 6.3 10.3 7.9 15.5 9.7 3.8 14.8 9.6 2.3 5.8 10.2 8.1 5.1 15.1 7.5 7.8 5.2 9.2 4.2 4.1 4.5 26.1 9.9 7.3 6.8 6.0 4.0 5.1 8.7 10.2 8.1 4.2 17.0 7.3 9.3 3.5 13.6 6.8 7.8 3.5 9.5 9.4 5.7 7.5 8.0 16.1 14.1 11.8 6.5 5.2 17.1 15.2 6.7 3.1 5.8 14.0 5.4 4.7 5.8 1.8 28.4 3.6 12.2 10.2 2.8 13.2 13.8 1.2 1.9 5.4 12.8 4.2 11.8 6.5 4.9 20.1 15.5 10.6 4.9 1.9 12.9 6.9 5.1 3.7 6.9 5.5 3.6 2.3 0.0 1.0 2.8 1.0 1.7 0.5 1.0 0.8 2.4 0.5 0.6 4.5 0.5 2.9 5.4 0.6 0.3 3.4 4.1 3.2 4.0 3.3 4.3 6.0 5.3 5.1 3.8 5.8 5.2 3.7 9.6 14.1 13.1 8.4 2.8 4.8 3.1 2.8 0.3 3.2 2.8 3.2 8.6 5.6 1.8 2.1 2.0 14.3 23.9 1.9 4.8 0.2 2.9 4.2 5.8 4.2 2.1 1.9 5.1 2.5 3.4 25.5 4.2 10.8 2.6 8.2 4.9 6.4 0.0 2.1 12.8 0.0 10.4 4.6 1.3 5.0 10.2 5.4 16.9 12.9 2.6 7.2 4.5 3.9 6.0 12.8 3.8 8.4 5.1 21.8 3.8 12.2 2.6 0.0 5.1 6.1 0.0 0.6 2.4 1.4 1.9 5.0 2.2 8.3 4.9 TESMIN "CXCDC2, MTL5" ENSG00000132749 "Testis expressed metallothionein like protein" Q9Y4I5 11 68707440-68751520 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "testis: 52.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 9.6;Breast myoepithelial cells: 7.4;Endometrial ciliated cells: 31.5;Glandular and luminal cells: 27.0;Proximal tubular cells: 11.5" "Cancer enhanced" "Detected in many" "breast cancer: 6.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 11.9;T-47d: 23.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA018539 Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Vesicles, Cytosol" "HPA018539: " "unprognostic (1.99e-1)" "unprognostic (3.97e-3)" "unprognostic (1.34e-2)" "prognostic unfavorable (1.75e-5)" "unprognostic (3.22e-2)" "unprognostic (6.71e-2)" "unprognostic (1.76e-2)" "unprognostic (6.99e-3)" "unprognostic (2.54e-1)" "unprognostic (5.33e-2)" "unprognostic (2.19e-2)" "unprognostic (8.47e-2)" "unprognostic (5.27e-2)" "unprognostic (6.39e-2)" "unprognostic (2.99e-1)" "unprognostic (9.85e-2)" "unprognostic (3.17e-1)" 0.3 0.5 0.7 1.0 0.7 7.4 4.3 0.6 0.6 0.7 0.6 2.5 1.4 0.7 0.7 1.6 1.7 0.4 0.2 0.5 0.8 3.1 0.4 0.4 1.3 1.2 0.7 0.8 1.1 2.1 2.3 0.3 1.2 2.3 2.9 1.5 1.9 1.1 0.0 0.6 1.4 0.4 0.5 1.3 0.9 52.5 0.7 2.1 1.1 0.1 1.1 0.4 0.9 0.5 7.2 3.1 1.3 0.1 0.0 0.0 3.5 1.6 0.8 2.2 1.0 0.9 7.1 2.9 1.6 0.3 0.0 3.4 1.0 1.4 1.7 3.0 2.5 2.1 1.0 0.0 0.0 1.5 11.9 0.0 3.8 0.1 2.2 3.0 0.7 3.4 4.5 5.4 0.3 4.8 0.8 4.2 7.3 3.3 3.1 1.9 0.4 0.8 2.6 0.1 4.4 4.7 0.0 1.5 0.0 3.7 23.8 10.0 2.7 0.2 0.5 0.2 0.1 2.1 2.0 2.8 0.1 4.2 1.9 0.0 0.2 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 0.1 0.7 0.7 0.6 0.6 0.5 0.8 1.2 0.7 1.2 0.5 0.7 0.5 0.7 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 9.6 7.4 0.0 0.0 0.6 0.0 0.0 1.8 0.7 0.0 5.9 6.3 0.0 31.5 2.6 0.3 0.0 0.0 0.0 4.0 4.7 0.3 0.0 27.0 2.5 4.2 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.5 0.0 0.0 11.5 1.5 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 1.1 0.2 0.0 0.0 TET3 "hCG_40738, MGC22014" ENSG00000187605 "Tet methylcytosine dioxygenase 3" O43151 2 73984910-74108176 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Developmental protein, Dioxygenase, DNA-binding, Oxidoreductase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.7;skin 1: 16.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 88.5;Oligodendrocytes: 86.7;Suprabasal keratinocytes: 68.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050845 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Vesicles, Cytosol" "HPA050845: AB_2681256" "unprognostic (1.07e-2)" "unprognostic (1.21e-2)" "unprognostic (3.08e-1)" "unprognostic (1.12e-2)" "unprognostic (4.44e-2)" "unprognostic (2.75e-2)" "unprognostic (1.72e-3)" "unprognostic (1.46e-1)" "unprognostic (1.01e-1)" "unprognostic (9.83e-2)" "unprognostic (7.74e-2)" "unprognostic (2.03e-1)" "prognostic unfavorable (3.58e-5)" "unprognostic (2.05e-1)" "unprognostic (5.30e-1)" "unprognostic (1.55e-2)" "unprognostic (1.10e-1)" 2.2 1.6 3.7 5.2 2.4 19.7 3.0 6.3 13.7 2.5 0.0 4.1 5.4 2.0 1.4 7.6 1.9 2.5 1.2 9.3 1.7 1.6 3.9 4.1 3.7 2.0 1.5 1.5 2.6 2.0 1.5 4.6 2.2 2.5 4.3 3.6 4.2 1.1 1.2 16.2 6.0 2.1 0.6 3.8 4.3 1.6 2.7 5.8 2.3 1.3 4.1 3.4 4.0 5.8 9.0 8.0 14.5 8.9 1.2 1.3 26.4 1.8 2.4 3.4 2.7 16.6 8.1 14.9 3.5 2.4 1.6 9.4 13.0 5.2 3.6 6.7 5.2 19.2 7.0 5.6 5.1 20.2 11.3 2.0 13.3 4.2 9.9 4.3 5.3 10.3 13.4 4.8 2.0 14.6 10.0 13.0 8.1 7.7 2.7 15.4 9.1 5.2 3.8 16.5 18.1 15.5 4.0 10.3 4.9 5.7 6.6 16.1 6.7 3.7 15.4 1.8 6.8 4.2 2.0 12.7 2.4 13.9 4.9 0.1 0.4 0.2 0.0 0.4 0.1 0.2 0.1 0.1 0.2 0.1 0.1 0.1 0.4 0.1 0.1 0.2 0.1 0.2 3.7 2.4 6.3 13.7 9.3 1.7 2.0 1.5 2.2 0.6 2.7 5.8 4.2 6.4 9.0 31.3 6.4 49.5 3.5 4.2 14.8 16.3 8.0 5.8 2.9 2.8 8.0 1.8 20.9 7.0 7.3 10.5 0.0 3.5 4.7 18.8 11.9 6.6 6.0 24.8 88.5 4.4 30.1 3.4 13.7 29.6 2.5 6.2 3.6 6.1 10.1 10.1 45.7 8.0 8.2 26.9 23.2 0.8 0.6 26.9 10.6 54.4 27.1 1.5 2.1 41.7 86.7 6.2 7.7 3.0 4.8 6.2 10.3 1.5 11.9 8.6 0.0 3.8 7.7 0.5 2.6 24.4 68.2 2.5 5.5 2.3 6.9 7.0 TEX14 CT113 ENSG00000121101 "Testis expressed 14, intercellular bridge forming factor" Q8IWB6 17 58556678-58692055 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "testis: 27.0" "Group enriched" "Detected in many" 4 "Early spermatids: 23.3;Spermatocytes: 56.4;Spermatogonia: 16.2" "Cancer enhanced" "Detected in some" "breast cancer: 0.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 6.3;Karpas-707: 7.9;MCF7: 3.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA030620, HPA077020" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "Vesicles, Plasma membrane" "HPA030620: AB_10601598, HPA077020: AB_2732327" "unprognostic (1.21e-2)" "unprognostic (2.12e-1)" "unprognostic (2.06e-1)" "unprognostic (9.49e-2)" "unprognostic (2.48e-1)" "unprognostic (1.23e-2)" "unprognostic (1.10e-1)" "unprognostic (6.17e-2)" "unprognostic (2.07e-2)" "unprognostic (1.61e-3)" "unprognostic (2.67e-2)" "unprognostic (8.10e-2)" "unprognostic (1.76e-9)" "unprognostic (1.77e-1)" "unprognostic (2.54e-1)" "unprognostic (5.00e-3)" "unprognostic (5.88e-2)" 0.1 0.1 0.5 0.1 0.6 1.7 0.2 1.1 0.6 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.4 0.5 0.4 0.2 0.2 0.1 0.5 0.5 0.3 0.1 0.0 0.2 0.1 0.5 0.2 0.0 1.1 0.1 0.0 0.0 0.1 0.1 0.0 0.5 0.2 0.1 27.0 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.0 0.1 1.7 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.2 0.0 0.1 6.3 0.9 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.1 7.9 0.0 3.3 0.3 0.0 0.4 0.1 0.1 0.3 0.2 1.2 0.0 0.1 0.9 0.1 0.0 0.0 0.4 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.3 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 1.1 0.6 0.4 0.5 0.5 0.5 0.5 0.5 0.5 0.8 4.4 0.0 0.0 2.9 5.7 0.9 1.8 0.7 2.8 0.6 4.7 7.2 1.3 5.7 1.5 1.8 0.0 1.6 0.7 0.1 0.0 0.0 23.3 0.4 0.2 1.5 0.0 0.0 2.2 0.0 1.0 0.7 0.5 1.8 1.3 0.2 1.4 0.8 3.7 0.0 2.2 0.5 2.0 0.6 2.3 6.4 0.3 4.6 3.6 2.8 0.0 0.6 1.0 1.0 3.0 0.1 0.0 0.4 4.3 0.7 0.0 0.1 0.2 1.3 0.0 1.2 1.5 56.4 16.2 1.7 0.1 1.1 0.7 0.0 0.0 0.4 TEX38 "ATPAF1-AS1, C1orf223, LOC374973, THEG4" ENSG00000186118 "Testis expressed 38" Q6PEX7 1 46668855-46673594 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 416 "testis: 388.6" "Group enriched" "Detected in some" 52 "Early spermatids: 2382.9;Late spermatids: 5035.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA073711 Approved Vesicles NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA073711: " "unprognostic (8.46e-2)" "unprognostic (1.99e-1)" "unprognostic (3.14e-2)" "unprognostic (8.86e-2)" "unprognostic (6.81e-3)" "unprognostic (3.50e-1)" "unprognostic (1.99e-1)" "unprognostic (9.21e-2)" "unprognostic (5.39e-2)" "unprognostic (4.15e-3)" "unprognostic (4.93e-4)" "unprognostic (2.64e-1)" "unprognostic (5.28e-2)" "unprognostic (2.84e-2)" "unprognostic (7.96e-2)" "unprognostic (7.84e-2)" "unprognostic (3.48e-1)" 0.2 0.2 0.2 0.0 0.3 0.1 0.4 0.3 0.4 0.1 0.0 0.1 0.0 0.2 0.9 0.1 0.1 0.1 0.1 0.2 0.3 0.3 0.2 0.1 0.0 0.1 0.1 0.1 0.2 0.6 0.8 0.2 0.1 0.5 0.1 0.2 0.2 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.2 388.6 0.2 0.1 0.4 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.4 0.3 0.2 0.4 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.3 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.3 0.3 0.4 0.2 0.3 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2382.9 0.2 0.1 1.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5035.0 28.3 1.5 0.0 1.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 18.4 0.1 0.0 0.0 0.0 0.0 0.3 6.6 0.1 0.0 71.0 14.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 TEX55 "C3orf30, FLJ32859, TSCPA" ENSG00000163424 "Testis expressed 55" Q96M34 3 119146151-119160042 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 168 "testis: 53.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA062468, HPA068480" Enhanced Approved Vesicles NA NA "Cluster 74: Testis - Spermatogenesis" Vesicles "HPA062468: AB_2684772, HPA068480: " "unprognostic (4.06e-3)" "unprognostic (3.67e-2)" "unprognostic (2.66e-1)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TFAP2D TFAP2BL1 ENSG00000008197 "Transcription factor AP-2 delta" Q7Z6R9 6 50713526-50773033 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "brain: 6.3" "Cell type enhanced" "Detected in single" "Horizontal cells: 1.7" "Cancer enriched" "Detected in single" 10 "lung cancer: 0.5" "Region enriched" "Detected in some" 5 "midbrain: 6.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HAP1: 1.0" "Region enriched" "Detected in many" 4 "midbrain: 11.8" "Region enriched" "Detected in some" 6 "midbrain: 9.4" HPA048962 Uncertain "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Golgi apparatus, Vesicles" "HPA048962: AB_2680573" 0.0 0.0 0.6 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.1 0.0 0.3 0.2 0.0 0.0 6.3 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TFDP2 Dp-2 ENSG00000114126 "Transcription factor Dp-2" Q14188 3 141944428-142149544 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 169.7" "Cell type enhanced" "Detected in all" "Early spermatids: 986.1;Late spermatids: 397.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "JURKAT: 216.4;MOLT-4: 423.3;REH: 222.7;U-698: 366.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018396, HPA070399" Supported Supported "Nucleoplasm,Vesicles,Mitotic spindle" Yes No "Cluster 49: Eosinophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "Vesicles, Mitotic spindle" "CAB018396: AB_2287284, HPA070399: " "unprognostic (1.35e-2)" "prognostic favorable (6.32e-4)" "unprognostic (8.08e-3)" "unprognostic (2.90e-2)" "unprognostic (4.69e-2)" "unprognostic (1.18e-1)" "unprognostic (1.14e-3)" "unprognostic (2.60e-3)" "unprognostic (5.42e-2)" "unprognostic (1.46e-1)" "unprognostic (5.04e-2)" "unprognostic (2.04e-1)" "prognostic favorable (9.84e-4)" "unprognostic (6.04e-2)" "unprognostic (3.91e-2)" "unprognostic (2.45e-1)" "unprognostic (1.08e-1)" 18.8 15.1 7.8 9.2 8.9 50.3 18.9 21.2 12.7 12.1 8.2 14.8 22.7 15.3 15.9 13.7 14.7 19.4 26.0 9.0 7.0 29.5 17.3 11.8 10.5 12.5 10.6 23.3 12.4 16.7 13.0 28.4 12.4 19.4 14.0 13.2 12.3 13.7 28.5 11.9 21.3 14.4 7.4 9.5 12.4 69.9 8.2 169.7 21.6 21.3 10.6 11.2 10.2 10.0 32.8 14.7 61.6 49.4 20.3 21.9 134.0 16.3 18.8 25.5 40.2 19.2 32.2 115.8 73.7 18.7 44.6 19.5 15.8 31.2 35.8 46.9 28.5 140.4 21.5 26.0 19.6 43.1 47.8 20.6 22.8 27.8 26.9 23.5 18.3 216.4 53.5 6.8 44.3 25.4 423.3 16.1 49.6 17.2 20.0 222.7 42.2 27.0 29.4 16.5 26.9 25.0 54.5 19.5 29.0 45.3 46.7 21.9 12.0 24.2 21.9 19.8 20.7 20.7 20.5 366.5 19.4 11.4 11.6 69.3 4.0 48.0 28.0 6.9 10.9 14.7 12.8 14.9 9.8 18.7 18.6 22.2 4.4 37.4 10.0 33.7 12.8 12.5 7.8 8.9 21.2 12.7 9.0 7.0 12.5 10.6 12.4 7.4 8.2 10.0 29.7 32.1 30.6 64.0 24.2 25.1 52.1 30.4 43.3 33.0 45.1 36.8 87.6 45.8 30.7 47.8 33.3 235.4 98.5 23.1 93.9 36.8 986.1 63.9 51.1 26.8 38.6 171.9 194.6 26.4 125.2 44.0 15.8 35.8 33.5 84.8 27.8 39.8 27.8 37.0 166.7 27.1 40.7 13.5 15.4 397.5 77.0 27.0 5.4 51.5 14.9 26.1 128.8 61.9 116.6 27.2 25.7 75.2 25.2 36.3 87.5 98.4 43.1 34.5 26.3 96.7 38.6 75.4 75.6 31.3 20.0 99.2 42.9 72.4 42.0 36.0 TFG "FLJ36137, SPG57, TF6" ENSG00000114354 "Trafficking from ER to golgi regulator" Q92734 3 100709295-100748964 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019473, HPA052206" Approved Supported Vesicles,Cytosol No No 320000 "Cluster 38: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 55: Plasma cells - Humoral immune response" Vesicles Cytosol "HPA019473: AB_1857936, HPA052206: AB_2681760" "unprognostic (1.14e-1)" "unprognostic (3.58e-2)" "unprognostic (1.46e-1)" "unprognostic (2.94e-2)" "unprognostic (1.46e-1)" "unprognostic (4.14e-2)" "prognostic unfavorable (5.48e-4)" "unprognostic (3.31e-3)" "unprognostic (1.42e-1)" "unprognostic (3.73e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (4.58e-3)" "unprognostic (3.72e-2)" "unprognostic (2.82e-1)" "unprognostic (8.55e-2)" "unprognostic (3.33e-1)" "unprognostic (8.45e-2)" 62.2 73.0 40.7 37.2 40.4 37.4 52.4 43.5 46.4 53.9 46.7 63.8 89.8 52.0 78.5 85.7 51.2 56.4 82.6 41.3 45.4 71.9 113.9 55.6 29.4 44.2 43.2 48.2 66.7 89.0 64.1 79.2 44.4 47.9 69.6 40.9 60.6 61.3 75.5 58.9 76.6 66.5 43.2 42.6 54.4 47.7 42.3 40.6 64.1 58.2 54.9 61.6 57.3 44.4 203.8 107.5 126.7 79.0 160.1 176.4 163.9 141.1 190.4 182.5 213.0 136.0 96.1 24.7 103.3 180.4 141.3 143.1 143.4 161.5 216.2 123.8 87.4 99.7 69.3 130.0 183.3 70.2 51.8 149.3 216.6 108.4 190.8 165.1 165.5 44.5 73.1 63.5 191.9 143.9 63.3 56.7 122.5 193.8 169.3 55.5 77.8 89.0 226.5 125.9 96.4 93.1 95.0 118.2 175.8 103.4 141.7 103.1 113.1 103.0 130.8 48.4 104.4 56.2 65.8 92.1 171.2 79.7 130.7 84.3 43.6 42.8 30.8 45.2 37.4 37.4 31.6 34.5 43.1 35.9 29.4 29.7 26.1 43.1 44.8 29.3 41.0 37.0 40.7 40.4 43.5 46.4 41.3 45.4 44.2 43.2 44.4 43.2 42.3 44.4 67.9 60.9 36.9 46.4 43.3 136.6 105.9 183.6 69.4 46.8 58.0 50.2 83.5 48.6 93.1 36.8 25.0 211.6 43.1 111.8 137.0 190.3 101.5 70.8 70.4 70.2 52.6 27.1 54.8 107.7 201.5 97.8 47.4 79.0 76.8 62.9 53.9 68.4 86.2 57.2 59.2 128.5 122.1 27.3 84.9 45.5 70.8 43.6 64.0 38.4 98.5 88.0 28.8 49.3 55.0 130.5 91.0 74.1 75.8 133.5 202.5 106.4 63.9 60.3 39.5 81.3 87.2 79.2 51.5 68.0 118.9 284.4 43.2 90.0 97.2 123.0 TGFA ENSG00000163235 "Transforming growth factor alpha" P01135 2 70447284-70554193 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.3" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 59.3;Pancreatic endocrine cells: 74.5;Urothelial cells: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 11.3;eosinophil: 23.8;neutrophil: 23.8" "Lineage enriched" "Detected in many" 5 "granulocytes: 23.8" "Cell line enhanced" "Detected in many" "A-431: 72.5;CAPAN-2: 82.5;HBEC3-KT: 72.3;OE19: 54.6;RPTEC TERT1: 72.6;U-87 MG: 69.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042297 Approved Approved Vesicles "Secreted to blood" No No 57900 "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "HPA042297: AB_10793878" "unprognostic (1.23e-1)" "unprognostic (1.06e-3)" "unprognostic (3.57e-3)" "unprognostic (6.39e-2)" "unprognostic (1.41e-1)" "unprognostic (8.49e-3)" "unprognostic (1.52e-1)" "unprognostic (3.00e-3)" "unprognostic (6.69e-2)" "unprognostic (9.21e-2)" "prognostic unfavorable (1.20e-5)" "unprognostic (7.74e-2)" "unprognostic (3.70e-2)" "unprognostic (1.60e-1)" "unprognostic (9.21e-2)" "prognostic favorable (1.52e-4)" "unprognostic (9.19e-2)" 2.2 0.5 9.2 5.0 16.8 1.6 6.9 15.0 12.2 6.1 5.2 10.7 8.5 1.3 2.9 25.5 6.1 14.1 0.7 10.4 11.7 13.4 4.5 3.9 4.1 21.0 15.8 0.1 7.5 3.0 0.5 1.9 18.5 2.4 7.9 7.4 6.4 1.2 0.1 12.2 10.0 1.4 16.6 5.8 8.5 2.5 13.2 1.0 8.1 0.3 9.0 10.0 12.8 27.3 72.5 11.3 0.1 0.2 0.0 0.0 0.0 11.0 0.0 0.3 0.1 0.2 82.5 0.0 43.2 0.4 11.2 37.1 0.6 72.3 0.1 0.1 1.6 0.0 1.8 6.0 0.0 0.9 0.1 0.0 29.1 0.1 27.8 3.4 0.0 5.6 0.0 0.4 0.0 2.6 0.1 1.4 1.1 54.6 22.9 0.0 0.5 19.8 72.6 27.2 0.6 0.1 5.8 0.0 0.1 0.2 9.8 0.7 0.6 0.3 4.9 0.1 15.7 0.4 0.6 0.1 69.0 2.4 25.6 11.3 0.8 23.8 1.7 0.2 4.4 0.0 1.0 1.0 1.0 0.0 0.5 0.4 23.8 0.3 0.0 0.0 0.0 0.7 9.2 16.8 15.0 12.2 10.4 11.7 21.0 15.8 18.5 16.6 13.2 27.3 0.4 6.4 2.7 0.3 0.2 16.2 12.3 16.9 10.8 1.4 9.8 12.1 2.3 24.3 21.8 25.8 0.0 0.0 2.2 19.8 1.9 37.3 21.3 8.1 0.7 1.7 1.2 0.0 0.8 10.0 0.0 0.6 13.7 10.5 5.7 0.0 0.0 3.0 3.9 0.0 3.6 6.2 12.2 3.2 2.4 1.9 0.3 4.1 0.0 6.5 18.2 7.9 2.1 59.3 36.1 74.5 9.0 0.0 0.7 16.8 21.1 6.6 20.4 0.7 0.0 0.1 1.1 0.6 0.2 12.2 24.9 0.0 1.9 0.0 5.6 63.6 TGFB2 ENSG00000092969 "Transforming growth factor beta 2" P61812 1 218345336-218444619 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Aortic aneurysm, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.9;Astrocytes: 119.1;Muller glia cells: 87.1" "Cancer enhanced" "Detected in all" "glioma: 11.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 59.6;hTERT-RPE1: 155.6;U-2 OS: 58.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006134 Approved Vesicles "Secreted to blood" NA Yes 4890000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "HPA006134: " "unprognostic (7.24e-2)" "unprognostic (7.23e-2)" "unprognostic (6.32e-2)" "unprognostic (2.45e-1)" "unprognostic (1.79e-1)" "unprognostic (3.86e-1)" "unprognostic (3.44e-2)" "unprognostic (1.99e-1)" "unprognostic (2.19e-2)" "unprognostic (2.35e-1)" "unprognostic (1.32e-2)" "unprognostic (1.31e-1)" "unprognostic (2.43e-2)" "unprognostic (2.64e-3)" "unprognostic (1.23e-1)" "unprognostic (4.90e-2)" "unprognostic (6.04e-2)" 1.5 1.2 8.2 1.1 11.6 0.1 4.0 9.2 14.9 7.1 7.1 2.4 0.6 6.5 4.5 1.8 3.9 2.0 6.4 11.5 11.1 1.4 0.6 7.8 0.6 18.5 12.7 4.6 1.8 1.1 2.1 12.9 10.7 17.0 0.9 10.5 8.5 11.2 4.8 2.1 0.7 5.1 8.4 2.6 1.2 0.9 10.0 0.4 2.6 2.1 0.8 3.0 3.0 11.0 4.0 20.2 1.8 15.1 4.3 2.1 0.0 2.9 0.4 30.1 21.2 5.5 46.7 0.0 59.6 0.2 25.8 11.1 1.2 2.3 32.0 0.1 0.2 0.0 1.7 0.0 46.7 0.0 0.0 1.9 5.3 4.1 15.8 155.6 8.1 0.0 0.0 0.0 29.6 0.3 0.0 0.0 1.6 0.0 1.8 0.0 8.8 0.0 10.1 0.0 0.3 0.1 34.8 3.9 0.7 39.7 2.9 1.1 38.3 21.3 58.4 17.9 30.7 0.0 0.1 0.1 9.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 11.6 9.2 14.9 11.5 11.1 18.5 12.7 10.7 8.4 10.0 11.0 2.2 76.9 6.3 119.1 0.5 8.7 8.7 35.3 4.0 9.9 8.4 5.8 4.1 14.3 29.8 5.5 0.0 0.4 0.2 0.0 0.0 40.2 19.3 2.1 6.7 8.1 0.0 0.0 8.6 16.9 13.9 28.8 0.0 6.8 1.3 0.9 4.2 0.0 1.4 1.7 36.0 0.0 8.2 0.6 13.2 28.0 8.1 3.2 12.4 30.0 1.0 87.1 0.0 3.5 1.0 21.5 0.0 13.9 1.2 15.0 0.0 0.8 12.3 3.0 0.0 27.7 19.7 0.3 0.8 0.6 2.8 0.5 0.5 0.8 0.0 2.1 TGFB3 "ARVD, ARVD1" ENSG00000119699 "Transforming growth factor beta 3" P10600 14 75958097-75983011 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Growth factor, Mitogen" "Cancer-related genes, Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 28.8;Late spermatids: 48.9;Leydig cells: 27.1;Sertoli cells: 32.9;Smooth muscle cells: 24.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "SK-BR-3: 104.6;T-47d: 75.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA063582 Approved Vesicles "Secreted to blood" NA NA 44800 "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA063582: AB_2685049" "unprognostic (7.84e-2)" "unprognostic (1.89e-1)" "unprognostic (4.32e-3)" "unprognostic (1.29e-1)" "unprognostic (3.27e-2)" "unprognostic (1.58e-1)" "unprognostic (1.24e-1)" "unprognostic (9.79e-2)" "unprognostic (2.83e-2)" "unprognostic (1.51e-2)" "unprognostic (5.63e-2)" "unprognostic (4.10e-1)" "prognostic unfavorable (4.01e-7)" "unprognostic (6.38e-3)" "unprognostic (1.10e-1)" "unprognostic (1.22e-2)" "unprognostic (3.27e-3)" 22.2 13.0 43.4 15.8 45.8 1.0 15.6 33.5 58.4 46.6 18.4 12.8 4.1 25.5 9.6 7.7 14.5 36.6 27.9 31.2 38.4 20.5 17.6 25.7 7.2 40.9 42.3 8.0 27.7 9.9 8.3 55.4 40.0 43.6 4.8 1.8 10.8 17.9 38.6 5.0 6.6 34.3 38.9 5.3 14.1 4.5 42.2 6.5 12.3 11.0 8.8 45.8 16.2 70.1 1.1 1.5 1.1 13.4 2.1 4.3 0.4 1.0 1.5 0.7 0.7 0.8 3.4 0.1 1.0 2.8 0.4 0.9 2.9 0.7 0.3 0.8 1.5 0.1 3.5 1.5 2.7 0.6 0.9 10.2 0.4 1.0 0.4 2.3 3.2 2.7 1.5 6.3 0.8 7.0 0.8 0.8 0.4 0.8 5.3 3.3 4.2 0.7 1.2 0.6 21.9 6.3 4.3 104.6 0.8 1.5 75.2 0.5 0.8 2.0 4.5 2.1 5.8 0.8 1.3 0.4 3.6 1.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.4 45.8 33.5 58.4 31.2 38.4 40.9 42.3 40.0 38.9 42.2 70.1 8.6 0.0 2.8 5.5 0.8 4.5 1.2 2.1 1.2 0.7 15.1 6.1 3.6 0.0 3.3 1.8 4.2 0.5 1.2 1.3 0.0 0.5 16.4 2.6 9.9 10.2 0.0 0.0 1.3 1.3 0.4 28.8 0.0 2.4 0.0 0.5 7.9 0.8 0.9 0.0 3.0 2.6 6.1 0.6 4.4 48.9 27.1 0.9 10.6 1.0 0.7 2.1 3.1 5.5 4.7 0.4 0.1 12.8 0.5 20.6 1.4 0.4 4.2 3.9 32.9 13.9 24.4 0.4 1.4 2.4 3.1 1.4 1.3 1.6 0.4 0.8 TGFBR3L ENSG00000260001 "Transforming growth factor beta receptor 3 like" H3BV60 19 7914830-7919097 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 51 "pituitary gland: 106.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 7.3;Late spermatids: 8.6;Plasma cells: 9.2;Proximal tubular cells: 8.9;Sertoli cells: 13.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.4;REH: 4.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA074356 Enhanced Approved Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 14: REH - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA074356: AB_2686681" "unprognostic (1.57e-1)" "unprognostic (6.92e-2)" "unprognostic (3.07e-3)" "unprognostic (2.01e-2)" "unprognostic (2.63e-1)" "unprognostic (7.65e-2)" "unprognostic (9.51e-3)" "unprognostic (1.09e-1)" "unprognostic (6.96e-2)" "unprognostic (3.41e-2)" "unprognostic (2.81e-1)" "unprognostic (2.04e-1)" "unprognostic (3.50e-3)" "unprognostic (1.31e-1)" "unprognostic (2.66e-1)" "unprognostic (1.06e-1)" "unprognostic (8.62e-3)" 0.0 0.3 0.3 0.1 0.2 0.3 0.0 1.2 1.0 1.1 0.0 0.3 2.0 1.3 0.1 0.0 0.9 0.1 0.8 0.4 0.2 0.8 1.4 0.1 0.1 0.6 0.0 0.0 0.1 0.0 106.0 0.0 0.2 0.5 0.0 0.2 0.1 0.1 0.1 0.2 1.5 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.4 0.0 0.2 0.2 0.4 0.1 0.0 2.4 0.7 0.0 0.0 0.0 0.4 0.1 0.2 0.8 0.0 0.0 0.8 0.1 0.0 0.0 1.5 0.5 0.2 0.6 0.3 0.1 0.6 0.4 0.0 0.0 0.0 0.0 0.2 0.0 1.2 0.4 0.7 0.0 0.7 0.5 0.2 0.2 0.1 1.5 4.3 0.0 1.1 0.0 0.1 0.4 0.8 0.1 0.0 0.3 0.0 0.4 0.6 0.1 0.9 1.4 1.4 0.3 0.6 0.6 0.4 0.1 0.3 0.4 0.6 0.1 0.2 0.3 0.1 0.1 0.1 0.1 0.3 0.0 0.1 0.1 0.3 0.5 0.1 0.1 0.1 0.1 0.1 0.3 0.2 1.2 1.0 0.4 0.2 0.6 0.0 0.2 0.0 0.0 0.4 0.3 0.0 0.0 2.0 2.4 1.5 2.9 0.3 0.0 1.6 1.6 2.3 1.8 0.0 0.6 0.0 0.0 0.1 1.8 0.1 3.9 0.3 0.5 1.4 3.7 0.2 0.0 0.0 7.3 0.2 0.8 0.8 0.0 0.5 0.0 0.2 1.4 2.9 0.3 0.0 3.3 0.2 0.0 0.3 0.4 8.6 1.2 0.6 5.4 1.9 0.1 3.4 0.0 0.5 1.8 0.3 0.0 1.2 9.2 4.3 0.5 8.9 0.3 2.4 13.1 0.2 3.5 0.4 1.9 0.0 1.4 0.4 4.4 0.1 0.2 0.4 TGFBRAP1 "TRAP-1, TRAP1, VPS3" ENSG00000135966 "Transforming growth factor beta receptor associated protein 1" Q8WUH2 2 105264391-105329735 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037672, HPA038397" Approved Approved Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA037672: AB_2675597, HPA038397: AB_10669782" "unprognostic (1.66e-1)" "unprognostic (1.58e-2)" "unprognostic (8.99e-2)" "unprognostic (4.49e-3)" "unprognostic (3.02e-2)" "unprognostic (6.77e-2)" "unprognostic (5.63e-3)" "unprognostic (9.15e-2)" "unprognostic (2.25e-1)" "unprognostic (2.98e-2)" "unprognostic (2.29e-1)" "unprognostic (8.30e-2)" "unprognostic (8.82e-2)" "unprognostic (3.89e-1)" "unprognostic (1.07e-1)" "unprognostic (1.01e-1)" "unprognostic (1.62e-2)" 9.6 8.1 6.5 8.0 6.3 22.7 8.1 6.1 7.2 6.6 7.7 8.1 7.2 7.8 5.4 8.3 7.0 5.9 6.6 6.8 5.4 6.7 5.0 7.4 9.4 5.8 6.4 7.6 9.9 11.4 5.1 10.4 5.9 8.3 8.2 6.2 8.3 9.3 11.8 11.1 8.0 8.9 5.6 8.5 13.5 2.5 6.5 9.1 10.9 7.7 8.3 7.8 6.6 7.2 22.5 17.5 12.5 15.5 13.3 10.5 25.4 16.0 21.8 26.6 25.3 25.9 13.6 22.7 16.9 18.2 27.1 13.5 22.4 38.1 21.9 24.3 23.8 30.7 13.8 20.7 12.1 28.6 22.4 12.7 22.5 22.2 19.6 14.1 28.7 19.5 28.0 10.9 32.6 14.9 20.4 18.3 15.9 15.4 14.5 22.9 19.8 33.0 16.4 27.3 24.7 16.5 13.2 26.1 25.8 9.0 13.1 17.5 20.8 16.7 25.4 14.1 16.4 11.3 14.8 24.7 11.9 19.6 35.3 0.4 0.8 1.1 1.8 0.7 1.5 0.6 1.2 1.0 0.6 1.0 0.7 1.1 0.3 0.9 0.5 1.0 0.9 0.7 6.5 6.3 6.1 7.2 6.8 5.4 5.8 6.4 5.9 5.6 6.5 7.2 13.7 6.4 9.5 10.4 8.1 8.0 3.5 5.6 9.1 12.4 8.8 9.3 5.9 5.7 7.1 5.5 16.7 12.4 8.9 7.5 1.9 5.4 0.1 5.2 7.0 10.6 11.3 11.3 17.0 10.8 4.8 8.5 9.7 8.3 2.5 10.8 13.9 6.7 12.9 15.2 14.8 8.2 8.2 13.8 4.4 0.5 7.5 9.9 3.6 17.8 9.5 9.0 11.3 8.5 13.5 8.3 5.2 8.2 7.6 7.7 5.8 7.3 2.7 7.2 26.3 15.8 8.1 0.4 1.2 11.5 13.1 7.4 8.8 11.1 9.2 3.1 TGM1 "ICR2, LI, LI1, TGASE, TGK" ENSG00000092295 "Transglutaminase 1" P22735 14 24249114-24264432 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Keratinization "Acyltransferase, Transferase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "esophagus: 713.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 12.8;Basal respiratory cells: 63.6;Club cells: 18.8;Distal tubular cells: 29.4;Squamous epithelial cells: 34.7" "Group enriched" "Detected in many" 4 "cervical cancer: 30.8;head and neck cancer: 78.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 17.5;HaCaT: 24.2;HeLa: 16.2;MCF7: 17.5;SK-BR-3: 21.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015159, HPA040171, HPA070372" Enhanced Approved "Vesicles,Plasma membrane" NA NA 530000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" "CAB015159: AB_2202870, HPA040171: AB_2676869, HPA070372: " "unprognostic (2.95e-2)" "unprognostic (8.79e-2)" "unprognostic (2.92e-2)" "unprognostic (1.89e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-2)" "unprognostic (1.12e-2)" "unprognostic (2.39e-1)" "unprognostic (3.01e-2)" "unprognostic (6.72e-2)" "unprognostic (2.15e-1)" "unprognostic (1.94e-7)" "unprognostic (7.11e-2)" "unprognostic (7.38e-2)" "unprognostic (2.22e-3)" "unprognostic (1.86e-2)" 25.7 1.3 0.6 0.9 0.8 0.7 2.2 3.7 2.0 78.7 0.8 1.4 0.8 1.0 1.6 713.5 4.4 0.6 5.1 0.5 0.6 2.5 1.7 5.3 1.5 1.5 0.9 3.0 3.2 0.2 3.3 1.2 1.4 4.1 0.9 1.7 89.7 4.4 1.1 73.2 1.9 0.5 0.4 2.6 1.8 2.9 0.9 1.3 2.7 0.3 40.4 1.3 144.2 0.9 1.1 2.0 1.1 1.0 0.0 0.8 17.5 0.4 0.2 1.0 1.6 1.2 1.7 1.0 2.3 1.3 0.3 24.2 2.8 2.0 0.6 2.0 3.3 1.4 16.2 5.7 0.8 0.9 1.5 1.5 9.3 0.5 2.0 0.5 0.7 3.4 1.0 1.0 0.7 17.5 0.7 1.9 0.3 1.1 2.2 1.1 0.1 1.1 0.6 2.1 1.2 1.6 0.2 21.7 0.1 1.4 1.5 1.1 0.8 1.1 4.8 2.0 0.9 1.5 1.8 0.3 0.4 2.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 3.7 2.0 0.5 0.6 1.5 0.9 1.4 0.4 0.9 0.9 0.2 12.8 1.1 2.0 0.0 0.3 4.6 63.6 4.0 0.9 1.1 0.8 0.8 5.7 18.8 0.0 0.0 1.4 0.3 0.2 29.4 2.0 0.1 0.3 0.2 0.2 0.0 0.0 1.5 0.9 0.8 3.9 0.0 0.6 4.5 0.7 0.0 0.2 0.4 0.0 1.7 0.1 6.1 0.6 0.3 0.0 0.6 0.4 0.0 1.0 0.4 0.2 0.0 1.0 1.0 2.6 0.0 0.4 0.1 7.4 0.1 0.2 2.1 0.6 0.0 0.1 1.0 0.0 0.6 34.7 1.8 1.2 0.6 1.2 0.3 6.2 THAP7 MGC10963 ENSG00000184436 "THAP domain containing 7" Q9BT49 22 20999104-21002196 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 162.9;Spermatogonia: 119.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 106.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003083 Approved Supported "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 30: Non-specific - Translation" "Cluster 18: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Nuclear membrane, Vesicles" "HPA003083: AB_1080264" "unprognostic (6.48e-2)" "unprognostic (2.13e-3)" "unprognostic (3.28e-1)" "unprognostic (4.89e-3)" "unprognostic (1.92e-2)" "unprognostic (1.82e-3)" "unprognostic (5.56e-2)" "unprognostic (1.40e-2)" "unprognostic (2.82e-1)" "unprognostic (2.74e-3)" "unprognostic (1.27e-3)" "unprognostic (2.23e-2)" "unprognostic (9.15e-2)" "unprognostic (2.29e-2)" "unprognostic (1.83e-1)" "unprognostic (3.72e-2)" "unprognostic (3.51e-3)" 16.1 26.9 13.7 5.6 12.9 4.8 18.1 13.7 19.6 23.0 16.0 23.1 7.9 20.4 4.8 15.4 20.9 5.8 19.4 12.6 13.2 20.8 37.8 13.4 8.8 14.1 14.9 21.9 26.9 9.8 39.5 4.2 14.4 29.1 2.5 2.7 19.0 9.2 39.7 19.1 19.0 3.5 13.3 24.2 23.2 35.5 13.9 7.6 20.9 14.4 3.7 21.5 16.6 13.2 23.5 25.0 6.9 11.8 6.0 7.5 14.2 12.1 11.6 15.9 14.7 11.5 13.5 17.2 11.9 7.6 8.4 16.4 6.1 12.1 2.4 17.1 36.4 21.6 18.7 14.9 18.5 22.2 13.4 7.2 15.0 14.0 12.9 7.0 8.4 13.1 106.2 19.8 8.8 29.3 24.4 13.7 9.6 16.0 24.7 19.0 13.6 10.4 8.4 11.8 13.5 11.7 15.1 19.5 21.5 3.2 22.4 14.6 5.5 25.4 19.5 15.4 12.8 27.6 17.4 14.1 27.6 14.3 22.4 1.9 22.1 8.8 27.2 23.9 36.1 50.0 32.8 27.4 21.3 36.9 45.2 36.3 1.9 24.0 25.3 31.6 30.7 24.9 13.7 12.9 13.7 19.6 12.6 13.2 14.1 14.9 14.4 13.3 13.9 13.2 18.7 16.0 25.7 6.2 33.3 19.1 20.3 24.5 14.8 31.5 25.0 30.4 14.8 37.1 18.3 25.8 14.6 31.2 23.8 22.4 64.6 28.2 30.0 16.6 15.7 20.3 22.2 16.2 5.8 38.2 30.1 25.8 20.4 10.6 21.5 21.0 18.5 35.3 27.8 13.5 5.8 22.8 30.5 15.8 11.5 44.0 41.7 14.2 40.9 1.0 27.5 52.0 45.3 3.5 7.2 23.9 19.7 32.4 28.6 31.4 38.4 57.4 22.6 27.1 39.5 22.8 43.5 162.9 119.4 16.7 16.3 29.6 28.8 31.1 21.7 13.2 THBS3 ENSG00000169231 "Thrombospondin 3" P49746 1 155195588-155209051 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 29 "Early spermatids: 297.1;Late spermatids: 1075.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 76.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA006293, HPA073242" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 9400000 "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "HPA006293: AB_10602898, HPA073242: AB_2732223" "unprognostic (2.57e-1)" "unprognostic (1.63e-2)" "prognostic unfavorable (2.43e-4)" "prognostic unfavorable (1.44e-4)" "unprognostic (2.63e-1)" "unprognostic (1.30e-1)" "unprognostic (3.62e-2)" "unprognostic (4.23e-1)" "unprognostic (4.54e-2)" "unprognostic (1.20e-1)" "unprognostic (1.88e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (2.38e-12)" "unprognostic (2.06e-2)" "unprognostic (9.41e-2)" "unprognostic (8.50e-3)" "unprognostic (2.26e-1)" 16.7 9.3 4.5 8.9 5.1 9.1 16.3 3.0 5.3 24.9 7.9 25.0 5.4 33.6 21.0 14.1 24.4 16.7 23.2 4.9 5.4 16.4 14.5 15.6 5.7 4.8 6.7 24.9 19.1 10.8 15.9 8.8 4.5 20.0 10.7 4.7 13.3 15.5 5.8 18.8 14.1 28.6 3.3 11.0 14.5 14.9 6.4 4.4 23.6 8.0 6.2 18.8 19.4 4.2 3.3 7.8 28.3 28.9 15.1 17.5 1.7 13.3 19.6 6.1 10.9 1.0 24.0 2.2 14.7 29.4 1.8 7.9 0.8 5.0 4.5 5.3 1.9 1.9 9.8 1.1 16.3 1.6 3.9 30.3 17.2 8.9 12.2 76.2 11.0 4.9 1.7 4.6 5.5 12.0 1.3 3.0 6.5 6.9 3.9 26.2 1.2 5.3 12.7 8.2 41.7 23.8 3.4 6.5 6.8 40.7 19.1 4.1 8.5 20.1 4.6 3.8 4.7 11.1 1.4 0.5 18.2 1.7 1.7 0.0 1.6 0.6 0.6 0.8 0.4 0.5 0.9 0.7 1.3 0.2 1.0 0.3 0.7 0.3 0.2 0.2 1.7 0.8 4.5 5.1 3.0 5.3 4.9 5.4 4.8 6.7 4.5 3.3 6.4 4.2 4.0 0.0 14.3 7.2 1.4 7.9 2.6 3.1 4.6 2.5 6.6 6.1 1.7 5.7 2.8 0.0 0.0 1.7 3.5 3.3 1.9 4.9 297.1 5.3 10.3 5.6 4.8 0.8 11.2 2.5 1.8 22.6 5.6 5.0 0.0 7.5 2.9 5.4 9.9 8.4 6.3 4.3 6.1 3.8 8.6 1075.2 23.3 3.7 10.6 0.0 1.9 1.5 1.0 0.0 3.2 3.7 2.9 10.1 1.4 2.3 2.7 3.8 2.6 3.7 0.0 11.8 8.1 20.8 4.8 3.7 5.3 1.4 2.2 2.4 3.4 2.2 THBS4 ENSG00000113296 "Thrombospondin 4" P35443 5 79991311-80083287 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Tissue remodeling, Unfolded protein response" "Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 216.7;heart muscle: 167.9;smooth muscle: 251.4;tongue: 214.6" "Cell type enriched" "Detected in many" 4 "Sertoli cells: 493.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 46 "eosinophil: 4.5" "Lineage enriched" "Detected in single" 46 "granulocytes: 4.5" "Cell line enhanced" "Detected in some" "AF22: 3.1;THP-1: 7.0;U-2 OS: 2.8;U-266/70: 2.6" "Region enriched" "Detected in many" 8 "white matter: 85.7" "Region enriched" "Detected in many" 27 "spinal cord: 89.3" "CAB004597, HPA042426" Approved Approved Vesicles "Secreted to extracellular matrix" NA NA 510000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" Vesicles "CAB004597: AB_628352, HPA042426: AB_2677992" "unprognostic (1.41e-1)" "unprognostic (5.33e-2)" "unprognostic (4.26e-3)" "unprognostic (3.64e-2)" "unprognostic (9.94e-2)" "unprognostic (8.10e-2)" "unprognostic (5.64e-2)" "unprognostic (7.12e-2)" "unprognostic (1.66e-1)" "unprognostic (2.25e-1)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (1.96e-3)" "unprognostic (2.74e-2)" "unprognostic (3.98e-2)" "unprognostic (1.76e-3)" "prognostic unfavorable (3.33e-4)" 216.7 1.2 15.4 5.2 19.6 10.6 26.8 13.8 13.0 2.1 5.0 58.1 2.2 26.8 1.6 6.0 2.5 10.4 167.9 12.2 24.5 0.7 0.3 1.3 1.1 22.3 25.3 4.1 22.8 35.7 14.3 0.2 19.9 9.0 8.7 7.5 46.5 5.7 77.2 2.9 3.3 251.4 21.7 0.3 8.6 8.7 28.0 3.6 27.0 214.6 4.0 3.5 5.8 20.0 0.1 0.0 3.1 0.2 0.2 1.3 0.3 0.1 0.1 0.9 0.3 0.1 0.4 0.1 0.1 0.2 0.8 0.1 0.1 0.4 0.8 0.1 0.4 0.3 0.0 0.2 1.7 0.0 0.0 0.9 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.2 0.2 0.5 0.0 0.0 2.4 0.0 0.0 0.0 0.9 0.0 0.2 0.0 2.5 0.7 0.0 0.0 0.2 1.3 0.0 7.0 0.0 0.0 2.8 0.2 0.2 2.6 0.1 0.4 1.1 2.2 0.6 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 19.6 13.8 13.0 12.2 24.5 22.3 25.3 19.9 21.7 28.0 20.0 57.0 0.0 1.1 37.2 0.7 0.3 0.1 0.2 2.2 1.3 0.8 1.8 9.1 0.0 0.7 3.7 56.3 0.1 0.5 0.0 0.0 0.2 40.8 0.3 0.8 9.4 9.0 0.0 9.7 0.0 0.0 84.2 0.5 0.3 0.0 5.9 0.4 0.2 0.1 1.7 12.7 0.0 0.0 0.0 0.3 7.2 0.9 2.7 1.8 6.5 0.0 2.2 0.0 60.3 24.0 0.0 0.0 43.6 0.3 1.0 0.0 0.8 0.2 1.9 493.0 78.9 116.9 14.5 2.1 0.6 1.0 0.0 2.1 1.2 0.0 0.0 THOC3 "MGC5469, TEX1" ENSG00000051596 "THO complex 3" Q96J01 5 175917873-176034680 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 132.1;Early spermatids: 187.0;Squamous epithelial cells: 226.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042764, HPA044009, HPA045071" Approved Enhanced Nucleoplasm,Vesicles No No "Cluster 20: T-cells - T-cell receptor" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm Vesicles "HPA042764: AB_10965055, HPA044009: AB_10959603, HPA045071: AB_10959461" "unprognostic (1.13e-1)" "unprognostic (1.44e-1)" "unprognostic (1.85e-3)" "unprognostic (6.48e-3)" "unprognostic (8.60e-2)" "unprognostic (3.57e-2)" "unprognostic (3.06e-3)" "unprognostic (2.02e-2)" "unprognostic (3.41e-2)" "unprognostic (1.11e-2)" "unprognostic (1.04e-1)" "unprognostic (4.04e-2)" "unprognostic (8.80e-3)" "unprognostic (3.20e-1)" "unprognostic (2.86e-1)" "unprognostic (3.16e-2)" "unprognostic (2.91e-1)" 12.0 14.5 22.0 11.4 15.9 35.1 21.4 23.0 40.6 23.1 19.1 27.0 12.5 13.4 63.2 82.9 15.1 8.0 9.3 40.2 14.9 16.3 22.2 11.9 29.1 15.5 13.3 18.8 15.3 10.0 15.9 17.4 15.9 14.6 21.1 12.1 22.5 14.9 12.6 26.5 16.2 12.2 13.2 17.7 17.5 51.3 15.4 39.2 20.5 17.6 45.5 17.4 33.5 15.9 82.1 44.7 47.0 102.7 44.1 39.3 168.0 48.4 44.6 104.5 120.4 63.5 65.2 105.6 68.3 27.9 112.6 69.2 71.6 206.0 109.7 73.5 103.3 57.3 46.2 70.7 14.6 94.6 49.2 33.3 85.9 90.0 45.2 23.3 58.3 98.0 88.1 46.5 66.9 98.7 64.0 57.9 40.1 82.3 160.3 110.7 59.3 110.4 75.2 60.7 89.5 51.4 100.0 48.5 52.5 67.4 55.3 86.1 45.1 35.9 40.8 55.6 88.2 23.2 44.1 64.4 26.7 90.1 28.5 16.5 26.9 15.1 39.3 33.5 48.4 49.6 81.7 48.9 43.1 70.6 99.7 62.4 3.9 42.3 31.5 39.8 133.6 59.1 22.0 15.9 23.0 40.6 40.2 14.9 15.5 13.3 15.9 13.2 15.4 15.9 14.9 12.8 8.6 2.0 35.8 44.5 34.1 64.5 132.1 12.3 17.7 18.0 4.0 10.0 24.4 25.8 10.4 40.8 25.1 8.1 41.1 25.1 187.0 50.2 18.4 16.1 16.8 63.9 5.2 19.2 84.3 15.2 26.5 44.9 12.0 18.8 13.9 20.3 24.6 6.7 3.7 16.3 26.4 13.2 14.9 122.0 14.6 14.3 8.8 1.9 15.4 8.9 27.8 4.5 2.0 21.9 11.6 19.2 55.9 18.4 10.4 46.8 15.8 12.0 19.7 10.6 22.8 107.9 48.3 226.5 40.9 20.0 33.3 25.0 27.7 31.1 TIAL1 TIAR ENSG00000151923 "TIA1 cytotoxic granule associated RNA binding protein like 1" Q01085 10 119571802-119597029 "Predicted intracellular proteins" Apoptosis RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060962 Approved Nucleoplasm,Vesicles NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 59: Non-specific - Translation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Vesicles" "HPA060962: " "unprognostic (1.61e-2)" "unprognostic (9.30e-2)" "unprognostic (1.26e-1)" "unprognostic (3.76e-1)" "unprognostic (5.33e-2)" "unprognostic (3.91e-2)" "prognostic unfavorable (7.81e-6)" "unprognostic (5.54e-2)" "unprognostic (9.21e-2)" "unprognostic (3.89e-3)" "unprognostic (3.74e-1)" "unprognostic (1.32e-3)" "unprognostic (6.48e-3)" "unprognostic (6.35e-2)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (2.26e-2)" 32.2 29.7 14.3 26.8 18.3 49.0 31.3 27.5 20.2 32.2 16.7 33.2 23.9 43.6 37.4 46.1 29.8 28.7 31.5 13.0 15.7 29.9 34.1 30.6 40.1 15.8 15.3 35.3 36.3 28.2 28.3 32.5 16.9 27.1 27.8 29.6 34.9 18.6 58.1 35.3 35.8 25.6 14.7 35.1 35.0 32.6 15.4 25.0 32.0 21.7 27.6 29.3 34.2 24.5 50.0 26.8 68.9 83.5 35.8 53.9 34.0 46.1 46.1 31.7 36.5 22.1 51.1 48.2 29.4 31.6 24.9 53.8 42.3 25.0 42.9 63.5 34.1 30.4 47.1 36.6 29.2 57.5 52.3 41.1 30.3 30.5 76.1 137.9 41.6 32.9 23.2 47.7 33.3 15.2 62.2 60.5 37.9 29.5 24.3 43.9 52.2 35.2 43.3 26.7 19.3 32.8 39.2 35.0 40.4 35.1 30.9 29.5 38.9 34.9 25.2 35.6 47.2 35.5 62.3 48.4 31.7 57.9 27.1 2.5 2.5 2.4 3.8 2.3 4.2 3.2 4.3 3.7 2.5 2.8 4.5 4.8 2.5 4.5 3.0 4.1 4.6 1.9 14.3 18.3 27.5 20.2 13.0 15.7 15.8 15.3 16.9 14.7 15.4 24.5 64.6 44.8 60.1 24.5 72.7 63.6 75.8 54.0 66.6 55.7 52.7 53.1 37.9 42.9 54.7 23.9 31.3 66.0 87.3 54.6 46.9 54.4 13.7 45.2 69.1 58.5 52.7 90.7 37.7 54.7 108.3 57.8 48.9 53.3 35.4 73.7 57.1 49.6 58.4 45.4 50.6 46.5 30.5 57.0 46.4 8.2 61.2 61.3 37.4 38.4 79.7 49.3 61.8 54.8 91.9 70.0 43.4 45.1 73.7 99.1 49.5 48.0 40.7 48.9 52.6 53.9 63.6 62.9 49.1 72.6 64.2 77.4 80.6 53.6 53.8 94.2 TIGD6 DKFZp761E2110 ENSG00000164296 "Tigger transposable element derived 6" Q17RP2 5 149993118-150000654 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 20.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA044599 Uncertain Approved "Nucleoplasm,Vesicles,Actin filaments" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Vesicles, Actin filaments" "HPA044599: AB_10961286" "unprognostic (1.06e-1)" "unprognostic (3.25e-1)" "prognostic favorable (5.35e-4)" "unprognostic (1.94e-2)" "unprognostic (8.18e-2)" "unprognostic (3.00e-2)" "unprognostic (1.30e-3)" "unprognostic (7.48e-2)" "unprognostic (5.96e-2)" "unprognostic (3.85e-2)" "prognostic favorable (5.88e-4)" "unprognostic (1.94e-3)" "unprognostic (1.85e-3)" "unprognostic (1.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.33e-3)" "unprognostic (1.18e-1)" 2.6 3.6 2.1 1.7 2.4 1.3 4.7 2.7 2.4 2.5 2.6 2.8 2.2 2.4 5.1 1.7 3.1 2.3 2.0 2.0 2.3 3.6 2.8 2.4 1.9 2.2 2.3 3.9 3.2 11.2 2.6 2.6 2.2 4.1 2.5 3.5 3.1 3.0 1.4 2.7 2.0 2.6 2.1 2.1 2.9 4.0 2.2 2.3 3.0 2.2 2.0 2.4 1.7 2.5 2.1 5.7 3.8 8.2 10.7 8.8 5.9 6.0 6.3 4.6 4.6 3.7 3.7 1.0 5.3 7.1 5.7 3.7 3.4 4.4 5.4 4.7 2.8 1.8 3.1 2.0 9.5 2.6 4.4 9.0 8.3 5.9 7.7 5.4 3.6 4.1 2.5 4.7 5.8 5.0 3.4 1.2 1.5 2.7 4.8 3.9 4.3 2.7 4.4 3.0 2.9 3.8 4.2 6.7 9.1 4.6 7.5 4.5 4.9 3.7 2.8 4.1 4.5 3.5 1.4 2.7 5.9 2.8 5.9 0.0 2.2 1.2 1.5 2.3 1.3 1.4 2.0 1.5 1.9 1.7 4.2 2.6 0.0 3.4 1.3 1.0 2.2 1.5 2.1 2.4 2.7 2.4 2.0 2.3 2.2 2.3 2.2 2.1 2.2 2.5 3.1 12.8 2.7 1.3 2.2 2.2 6.6 2.9 2.2 6.2 5.4 3.7 5.4 4.3 4.7 3.7 0.0 5.2 2.6 2.0 7.9 5.1 1.2 2.9 3.5 2.7 3.0 0.4 1.4 4.7 2.7 3.5 7.1 3.6 3.8 4.6 3.3 1.8 4.2 3.3 1.6 2.6 6.1 1.9 1.9 2.1 4.4 2.6 3.6 2.8 4.8 6.3 1.0 4.5 5.6 4.3 1.9 3.4 3.8 5.7 3.1 7.9 3.6 6.3 0.0 2.1 3.8 20.0 8.7 2.6 1.1 3.6 2.2 6.8 2.0 4.9 TIMP3 SFD ENSG00000100234 "TIMP metallopeptidase inhibitor 3" P35625 22 32801705-32863041 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision" "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1663.5;Fibroblasts: 967.5;Leydig cells: 1398.6;Peritubular cells: 1934.1;Sertoli cells: 2327.1;Smooth muscle cells: 1116.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 502.6;BJ: 1173.0;BJ hTERT+: 514.7;fHDF/TERT166: 1073.7;WM-115: 893.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068391 Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" NA NA 700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "Golgi apparatus" "HPA068391: " "unprognostic (4.98e-2)" "unprognostic (1.77e-3)" "unprognostic (1.60e-1)" "unprognostic (8.53e-4)" "unprognostic (1.67e-2)" "unprognostic (1.05e-2)" "unprognostic (7.01e-2)" "unprognostic (3.22e-2)" "unprognostic (8.42e-2)" "prognostic unfavorable (1.90e-5)" "unprognostic (3.92e-1)" "unprognostic (1.95e-1)" "prognostic favorable (1.50e-4)" "unprognostic (2.66e-3)" "unprognostic (1.44e-2)" "unprognostic (2.55e-3)" "unprognostic (3.11e-2)" 805.5 288.7 71.7 41.4 74.9 1.1 556.9 68.7 72.6 376.1 221.0 190.4 30.5 393.3 230.4 168.1 373.9 153.5 532.8 64.3 79.2 248.0 92.0 625.1 69.5 83.2 86.7 116.2 81.1 139.5 139.1 999.5 76.0 178.8 81.2 31.7 178.7 341.1 128.1 170.3 122.1 379.6 70.3 187.2 152.1 64.1 106.2 41.1 340.1 325.9 28.8 197.4 261.1 59.5 19.6 0.0 16.9 2.7 502.6 280.6 1.0 1173.0 514.7 94.1 110.8 20.5 0.3 0.1 28.1 1073.7 3.6 18.3 3.2 48.4 135.0 0.1 14.3 147.4 23.5 52.4 197.4 0.1 59.7 47.4 120.4 166.9 9.5 3.4 0.0 0.0 0.1 0.9 44.6 1.2 0.4 5.0 2.5 0.0 0.8 0.1 3.4 0.4 2.1 97.0 12.5 16.8 24.1 0.5 322.9 266.6 0.7 1.3 0.0 7.9 25.2 245.9 19.1 0.2 0.4 0.4 232.3 0.2 893.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 71.7 74.9 68.7 72.6 64.3 79.2 83.2 86.7 76.0 70.3 106.2 59.5 1663.5 365.4 35.9 101.9 5.3 77.4 766.2 49.5 10.2 4.0 31.2 177.2 279.9 14.3 22.2 51.5 4.2 492.2 4.6 0.3 3.9 2.5 14.9 27.9 747.6 677.3 1.8 35.3 26.1 0.7 433.7 967.5 21.4 23.9 89.2 11.4 743.9 102.0 109.2 3.3 15.7 0.0 24.4 39.3 95.0 57.7 1398.6 28.6 76.5 116.2 0.7 146.6 0.0 52.3 0.8 0.9 0.0 1934.1 9.5 159.5 0.0 15.5 8.5 5.5 2327.1 339.2 1116.6 6.2 7.0 14.3 56.4 809.0 21.5 4.8 0.7 163.4 TIPRL "dJ69E11.3, MGC3794, TIP41, TIPRL1" ENSG00000143155 "TOR signaling pathway regulator" O75663 1 168178962-168202109 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027995, HPA054282" Approved Supported Vesicles,Cytosol NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Vesicles, Cytosol" "HPA027995: AB_10602900, HPA054282: AB_2682435" "unprognostic (3.18e-2)" "unprognostic (1.05e-1)" "unprognostic (5.05e-2)" "unprognostic (3.17e-1)" "unprognostic (3.80e-1)" "unprognostic (2.35e-3)" "prognostic unfavorable (1.60e-4)" "unprognostic (5.82e-2)" "unprognostic (3.32e-2)" "unprognostic (1.12e-2)" "unprognostic (4.30e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (1.45e-8)" "unprognostic (3.23e-1)" "unprognostic (1.57e-1)" "unprognostic (5.55e-2)" "unprognostic (8.61e-2)" 16.3 14.9 15.5 19.6 16.3 33.8 21.0 15.0 20.1 17.7 12.8 22.2 19.0 23.2 16.8 20.1 14.3 16.8 23.7 16.8 17.0 17.8 22.5 14.9 22.2 14.0 13.4 17.4 15.9 27.4 13.6 17.5 14.4 18.4 22.0 14.7 12.0 17.3 24.4 16.3 18.5 22.7 13.4 16.3 15.4 18.2 15.1 30.1 17.4 23.0 19.9 18.7 13.6 15.7 69.4 31.0 45.9 41.6 36.7 53.1 27.5 50.5 53.0 54.6 48.4 48.3 50.1 49.0 68.2 48.7 40.1 81.8 34.5 49.3 52.6 47.2 36.4 47.3 29.2 22.9 64.5 94.7 62.0 43.2 62.8 47.4 62.7 36.0 58.1 75.4 69.0 66.3 47.7 25.4 84.9 49.0 37.0 96.7 54.2 41.1 47.0 66.4 49.7 33.9 29.6 66.1 39.3 54.6 102.2 51.6 59.9 96.3 53.4 45.6 52.4 43.6 69.7 72.2 80.5 108.1 29.8 61.4 53.4 71.6 26.7 36.8 22.0 32.1 22.1 27.3 25.7 23.8 31.6 27.6 22.8 22.4 34.5 29.6 33.9 23.4 36.0 28.2 15.5 16.3 15.0 20.1 16.8 17.0 14.0 13.4 14.4 13.4 15.1 15.7 52.1 25.6 20.4 9.4 39.7 48.2 42.1 70.4 50.1 27.3 31.3 36.2 46.3 22.8 40.7 22.0 16.7 44.2 49.0 37.1 29.4 68.5 53.4 36.0 50.1 43.4 24.0 32.6 41.6 88.9 62.8 47.3 24.5 30.8 40.0 35.2 36.0 33.5 65.1 52.2 37.9 33.9 44.7 26.6 41.1 15.4 37.6 42.6 30.2 19.7 61.0 43.9 51.5 22.1 21.3 69.7 27.7 38.0 37.1 43.3 35.9 77.2 36.1 20.8 26.3 35.4 51.1 151.5 51.6 56.0 41.8 29.0 48.0 84.5 38.5 37.5 TLCD2 ENSG00000185561 "TLC domain containing 2" A6NGC4 17 1702816-1710377 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 129.3;Distal enterocytes: 112.4;Proximal enterocytes: 68.9;Skeletal myocytes: 124.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "basophil: 3.4;neutrophil: 1.6" "Lineage enriched" "Detected in single" 8 "granulocytes: 3.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 9.0;HaCaT: 8.4;SiHa: 11.2;T-47d: 9.4" "Not detected" "Not detected" "Region enhanced" "Detected in all" "spinal cord: 14.2" HPA046063 Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Vesicles Nucleoli "HPA046063: AB_2679520" "unprognostic (1.78e-1)" "unprognostic (6.71e-2)" "unprognostic (2.56e-2)" "unprognostic (1.20e-1)" "unprognostic (8.64e-3)" "unprognostic (1.64e-1)" "unprognostic (3.32e-1)" "unprognostic (4.04e-2)" "unprognostic (7.94e-2)" "unprognostic (7.74e-2)" "unprognostic (2.29e-3)" "unprognostic (2.56e-1)" "prognostic unfavorable (4.36e-5)" "unprognostic (3.77e-2)" "unprognostic (2.82e-1)" "unprognostic (7.79e-2)" "unprognostic (4.44e-2)" 10.3 9.4 0.6 1.8 0.7 2.1 4.7 1.6 0.9 3.0 2.3 7.3 6.0 1.8 1.2 4.7 2.7 1.8 2.1 0.6 0.5 1.8 7.0 3.9 0.7 1.0 0.7 2.5 1.2 1.0 1.1 1.5 1.0 1.9 5.3 10.5 2.9 0.9 1.7 2.4 6.9 1.2 0.7 1.3 4.7 0.6 1.0 0.1 1.6 0.8 0.8 3.1 3.5 1.6 1.0 1.1 1.1 3.5 8.1 9.0 0.3 1.9 1.8 1.0 0.7 6.9 3.1 0.1 1.9 3.1 1.0 8.4 1.5 0.9 0.7 0.2 0.7 0.9 2.4 0.3 2.3 0.1 2.4 7.6 3.2 1.2 2.2 2.9 0.7 0.1 0.8 0.4 0.9 1.9 0.1 0.4 0.1 3.4 0.6 0.1 5.3 0.2 0.7 2.7 0.2 0.4 11.2 1.0 1.6 1.5 9.4 0.8 2.6 0.5 2.3 2.1 0.5 0.1 0.1 0.1 0.6 0.3 1.0 3.4 0.2 0.4 0.2 0.1 0.1 0.2 0.3 0.1 0.0 0.4 0.2 0.2 1.6 0.3 0.1 0.2 0.1 0.1 0.6 0.7 1.6 0.9 0.6 0.5 1.0 0.7 1.0 0.7 1.0 1.6 19.0 51.3 55.5 0.3 1.6 0.0 8.2 0.0 4.0 7.9 5.8 9.5 2.7 17.2 18.0 11.0 129.3 4.9 2.0 112.4 0.0 7.3 1.1 12.9 10.4 14.1 9.0 11.2 0.5 9.6 2.6 14.9 20.9 13.3 15.8 3.9 18.9 24.2 5.5 0.0 0.4 24.6 0.0 6.5 0.0 1.8 13.4 10.7 0.0 3.7 1.4 11.7 0.0 0.0 0.1 13.5 40.1 5.7 3.3 6.3 68.9 1.1 19.9 57.8 6.6 124.2 17.8 0.6 0.8 9.1 0.3 4.0 5.1 5.4 35.7 13.0 TLCD5 "MGC17839, TMEM136" ENSG00000181264 "TLC domain containing 5" Q6ZRR5 11 120325296-120333686 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 51.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 28.3;Cytotrophoblasts: 10.0;Extravillous trophoblasts: 4.2;Fibroblasts: 6.1;Syncytiotrophoblasts: 9.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 2.2" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074432 Approved Vesicles,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" Vesicles Cytosol "HPA074432: AB_2686689" "unprognostic (1.02e-1)" "unprognostic (6.56e-2)" "unprognostic (1.49e-2)" "prognostic unfavorable (6.65e-4)" "unprognostic (1.65e-2)" "unprognostic (3.31e-2)" "unprognostic (6.81e-3)" "unprognostic (1.22e-1)" "unprognostic (1.39e-2)" "unprognostic (2.58e-1)" "unprognostic (2.86e-3)" "unprognostic (2.39e-1)" "unprognostic (2.71e-2)" "unprognostic (2.78e-2)" "unprognostic (1.34e-1)" "unprognostic (1.73e-1)" "unprognostic (7.28e-2)" 4.4 13.1 11.3 1.0 15.2 0.2 3.3 13.4 10.9 5.0 8.8 2.8 0.6 5.1 7.6 1.5 5.7 3.2 11.0 10.9 12.1 3.6 0.8 4.8 1.4 12.3 15.3 7.7 3.9 4.5 7.0 7.2 12.0 4.9 1.1 51.9 2.0 3.3 1.2 1.3 1.9 3.8 11.3 2.6 2.5 3.1 12.6 0.8 5.4 1.9 1.4 3.5 3.5 14.0 2.4 6.0 15.8 10.9 10.9 16.8 3.0 5.0 12.3 8.4 12.7 3.2 10.2 0.0 15.3 3.2 16.2 1.6 10.1 3.8 9.8 0.0 6.3 8.1 6.1 5.4 12.4 0.0 0.0 14.7 2.8 11.4 17.0 19.7 9.2 9.5 2.2 14.8 10.9 2.9 0.0 0.1 5.1 0.6 3.8 6.3 4.9 0.8 10.4 2.2 8.3 7.2 7.3 0.9 1.5 13.4 9.3 0.2 6.9 8.7 9.0 2.0 3.1 0.2 0.0 0.0 2.6 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.4 0.0 11.3 15.2 13.4 10.9 10.9 12.1 12.3 15.3 12.0 11.3 12.6 14.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.3 0.0 0.0 0.0 0.0 10.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 4.2 6.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 TLL1 ENSG00000038295 "Tolloid like 1" O43897 4 165873237-166104457 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Differentiation "Developmental protein, Hydrolase, Metalloprotease, Protease" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 20.0;placenta: 6.4" "Cell type enriched" "Detected in many" 4 "Oligodendrocyte precursor cells: 115.1" "Cancer enhanced" "Detected in some" "renal cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 6.0;Karpas-707: 9.6;PC-3: 3.3" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 8 "cerebellum: 45.8" HPA060767 Approved Vesicles "Secreted to extracellular matrix" NA NA 560000 "Cluster 6: Brain - Smell perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA060767: AB_2684357" "unprognostic (2.17e-1)" "unprognostic (6.45e-4)" "unprognostic (8.60e-2)" "unprognostic (2.65e-5)" "unprognostic (9.85e-2)" "unprognostic (2.51e-4)" "unprognostic (3.37e-2)" "unprognostic (3.61e-2)" "unprognostic (1.56e-1)" "unprognostic (5.07e-4)" "unprognostic (2.86e-2)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (2.13e-3)" "unprognostic (7.76e-2)" "unprognostic (6.91e-3)" "unprognostic (1.21e-5)" 3.1 0.5 0.7 1.0 5.9 0.0 2.7 20.0 8.9 1.8 0.0 1.2 0.6 1.1 0.3 0.7 1.3 2.4 0.7 9.9 5.4 1.6 0.1 1.2 1.0 3.5 6.9 0.3 2.3 0.8 0.9 6.4 4.4 0.9 0.9 1.8 0.8 0.8 0.4 1.4 1.8 1.4 0.0 0.0 0.7 0.4 3.0 0.3 1.4 0.4 0.8 1.6 1.5 1.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 1.3 0.3 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.6 0.0 0.1 0.0 6.0 0.0 0.0 0.0 0.0 0.3 1.1 0.0 1.3 0.0 0.9 0.0 0.0 9.6 0.0 0.0 0.0 0.1 0.9 0.0 3.3 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 5.9 20.0 8.9 9.9 5.4 3.5 6.9 4.4 0.0 3.0 1.1 10.2 0.0 0.6 0.0 0.0 1.8 0.3 1.3 0.6 14.1 0.2 0.1 7.1 1.5 1.8 0.0 0.0 4.4 0.0 0.0 0.0 1.5 0.1 0.0 2.0 18.9 0.0 0.0 24.9 2.0 1.4 2.4 0.0 0.1 0.0 0.0 2.5 0.0 0.3 8.4 8.0 0.1 0.0 0.0 1.0 0.0 3.1 0.1 1.8 10.3 0.0 0.1 0.0 115.1 0.5 0.1 0.0 4.5 0.0 1.1 4.0 1.1 0.8 0.7 0.0 0.2 0.3 0.1 0.2 0.1 1.7 1.9 0.8 0.0 0.6 0.2 TM2D1 BBP ENSG00000162604 "TM2 domain containing 1" Q9BX74 1 61681046-61725423 "Predicted membrane proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046058, HPA055621" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm Vesicles "HPA046058: AB_2679519, HPA055621: AB_2682865" "unprognostic (1.80e-1)" "unprognostic (1.99e-3)" "unprognostic (1.68e-1)" "unprognostic (2.20e-2)" "unprognostic (5.79e-1)" "unprognostic (5.23e-2)" "prognostic unfavorable (2.02e-7)" "unprognostic (1.08e-1)" "unprognostic (1.52e-1)" "unprognostic (1.19e-1)" "unprognostic (2.00e-1)" "unprognostic (2.28e-2)" "unprognostic (1.15e-2)" "unprognostic (4.60e-2)" "unprognostic (1.13e-1)" "unprognostic (1.19e-1)" "unprognostic (1.09e-1)" 30.9 36.3 25.4 16.5 26.0 23.2 35.8 27.3 36.5 29.4 27.6 27.7 20.5 30.3 45.3 21.4 29.9 26.0 45.4 25.2 27.0 38.8 29.3 27.4 26.5 26.7 27.0 36.4 21.8 41.6 20.4 35.7 26.8 33.3 28.5 26.2 30.1 22.5 40.9 19.8 25.0 29.3 27.1 23.9 24.4 34.9 25.9 25.1 40.6 35.3 20.3 30.1 20.7 28.4 31.3 15.0 22.8 18.2 68.1 66.2 29.2 54.5 55.2 26.4 35.0 9.7 39.0 25.3 70.9 45.9 52.7 34.8 29.2 39.7 40.5 41.3 34.4 28.2 23.0 21.8 66.7 40.9 48.0 74.2 67.0 30.5 38.0 64.4 50.5 33.6 32.7 47.7 64.7 10.1 20.9 32.0 24.9 27.5 21.4 17.9 43.1 31.5 78.4 24.3 25.4 30.9 32.5 64.1 102.6 30.5 35.1 43.2 45.3 35.3 17.8 19.8 41.9 40.0 39.4 30.8 61.3 39.4 31.8 52.8 18.7 44.9 16.1 23.7 16.6 24.2 18.6 19.7 18.6 20.1 17.2 19.9 12.2 23.3 26.8 36.4 24.3 19.4 25.4 26.0 27.3 36.5 25.2 27.0 26.7 27.0 26.8 27.1 25.9 28.4 49.5 41.7 40.2 32.3 49.0 78.3 91.9 205.2 59.2 60.3 67.7 56.6 40.5 48.6 99.9 79.1 60.5 51.2 47.4 46.5 39.2 50.3 6.5 43.3 34.7 59.2 43.9 42.1 42.3 45.3 60.0 84.3 29.0 42.2 61.5 37.6 80.7 54.2 50.3 69.0 46.9 41.3 158.7 58.7 53.8 9.9 79.9 48.1 90.7 43.1 54.1 99.2 63.8 50.3 63.4 54.2 60.4 53.0 51.4 110.0 45.9 67.6 100.0 70.1 39.5 75.3 60.0 172.1 72.5 58.6 76.4 53.5 47.3 42.0 43.0 110.1 TM2D2 BLP1 ENSG00000169490 "TM2 domain containing 2" Q9BX73 8 38988808-38996824 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 218.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047152, HPA050547" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles, Plasma membrane" "HPA047152: AB_2679957, HPA050547: AB_2681168" "prognostic unfavorable (7.49e-4)" "unprognostic (1.49e-1)" "prognostic favorable (1.71e-4)" "unprognostic (2.55e-2)" "unprognostic (7.02e-2)" "unprognostic (2.98e-1)" "unprognostic (5.17e-2)" "unprognostic (1.41e-1)" "unprognostic (3.69e-2)" "unprognostic (2.43e-3)" "unprognostic (4.58e-2)" "unprognostic (1.18e-2)" "unprognostic (1.14e-1)" "unprognostic (1.41e-1)" "unprognostic (1.61e-1)" "unprognostic (1.07e-2)" "unprognostic (8.61e-2)" 20.2 24.4 15.6 15.9 17.3 13.1 19.8 18.2 22.2 19.7 24.4 15.7 18.0 18.4 26.5 16.5 17.4 23.1 19.5 17.5 18.6 32.9 29.8 20.6 17.7 16.5 17.4 22.0 13.9 23.6 15.9 33.8 17.6 22.2 16.3 17.1 17.8 22.1 15.6 18.5 16.2 17.8 17.2 22.3 19.6 27.6 18.0 11.8 26.4 17.6 15.2 20.0 16.6 19.7 35.7 56.5 25.7 35.7 58.8 39.0 35.4 73.8 44.9 54.6 49.1 43.4 30.0 12.5 56.7 54.9 61.5 37.8 27.5 44.5 59.0 15.0 21.7 28.6 32.3 47.3 51.8 8.6 35.3 47.9 42.8 43.1 20.9 40.0 71.1 21.2 32.2 35.7 73.5 22.1 21.3 28.9 32.6 53.2 22.0 17.8 33.2 21.0 62.2 27.9 8.6 16.9 28.2 19.5 37.8 45.1 48.1 17.9 64.6 44.0 33.0 64.9 37.7 24.9 59.1 21.9 33.6 19.4 31.6 64.5 28.5 27.3 29.7 34.2 33.3 24.9 35.1 33.0 30.4 26.2 33.1 32.0 7.9 33.0 29.8 60.5 41.8 35.3 15.6 17.3 18.2 22.2 17.5 18.6 16.5 17.4 17.6 17.2 18.0 19.7 30.4 12.8 14.7 3.9 13.8 35.1 56.9 64.3 20.5 25.1 22.5 25.1 17.7 32.9 44.5 51.5 20.9 91.3 28.2 12.9 29.4 59.9 62.2 24.1 33.3 36.0 10.3 5.9 7.6 38.4 98.2 38.6 17.3 25.8 22.2 44.3 58.2 38.4 218.5 23.5 9.2 12.6 40.7 33.6 33.9 46.6 36.1 40.6 26.6 7.5 70.8 45.4 15.5 6.0 5.4 74.9 19.4 24.8 14.5 52.5 35.1 61.4 29.4 34.0 0.0 25.4 26.5 60.8 58.1 16.3 15.5 79.9 17.8 39.3 16.7 48.5 TM4SF18 L6D ENSG00000163762 "Transmembrane 4 L six family member 18" Q96CE8 3 149318498-149334414 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 33.9" "Group enriched" "Detected in many" 4 "Adipocytes: 226.1;Endothelial cells: 188.9;Hepatic stellate cells: 151.0" "Cancer enhanced" "Detected in all" "renal cancer: 17.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 94.8;EFO-21: 194.9;GAMG: 38.7;HUVEC TERT2: 65.9;NTERA-2: 47.2" "Low region specificity" "Detected in many" "HPA053639, HPA069378" Approved Supported Vesicles,Cytosol NA NA "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles Cytosol "HPA053639: , HPA069378: AB_2686133" "unprognostic (2.25e-1)" "unprognostic (3.68e-1)" "unprognostic (4.76e-2)" "unprognostic (1.08e-1)" "unprognostic (9.11e-3)" "unprognostic (1.05e-2)" "prognostic favorable (8.63e-4)" "unprognostic (2.84e-1)" "unprognostic (6.13e-3)" "unprognostic (1.64e-1)" "unprognostic (7.90e-3)" "unprognostic (1.75e-1)" "unprognostic (5.71e-2)" "unprognostic (3.56e-3)" "unprognostic (1.65e-1)" "unprognostic (3.01e-1)" "unprognostic (1.97e-1)" 21.3 5.2 9.4 4.9 9.6 0.1 16.3 9.2 11.5 8.3 10.4 3.4 3.9 7.6 4.7 3.4 6.4 10.6 8.4 9.1 10.3 19.1 7.9 9.2 6.6 12.2 9.6 3.2 9.8 6.8 3.1 17.4 11.5 4.0 3.3 1.1 4.0 6.5 5.9 2.4 3.6 14.9 10.0 33.9 3.4 1.9 12.1 2.1 12.7 5.7 5.0 6.7 2.5 10.4 0.1 94.8 3.5 0.2 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.2 1.2 0.0 194.9 0.0 38.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.3 0.0 0.3 0.1 0.7 0.0 0.0 0.0 24.7 65.9 0.0 0.0 0.0 6.2 0.7 0.0 0.2 47.2 0.0 0.0 0.1 2.6 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.5 1.5 0.1 0.1 8.4 0.1 1.2 0.0 0.5 0.1 0.1 0.5 0.0 0.1 15.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 9.4 9.6 9.2 11.5 9.1 10.3 12.2 9.6 11.5 10.0 12.1 10.4 226.1 0.0 4.4 0.3 1.6 3.2 0.2 0.0 0.6 0.2 41.4 23.9 2.8 4.3 0.0 1.8 0.0 0.0 1.0 0.0 9.8 35.2 0.4 0.7 1.1 188.9 0.0 0.0 0.0 0.2 0.0 6.2 0.0 0.9 1.3 0.3 151.0 1.1 0.1 0.0 0.1 0.0 0.0 9.1 3.0 1.8 2.1 1.2 1.8 33.7 0.6 0.4 0.0 0.5 0.6 0.9 0.0 6.8 2.5 1.3 0.0 35.8 0.7 0.0 0.0 1.5 2.5 0.2 0.5 0.2 2.8 0.0 1.1 5.2 0.0 0.6 TM7SF2 "ANG1, DHCR14A, NET47" ENSG00000149809 "Transmembrane 7 superfamily member 2" O76062 11 65111845-65116384 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 246.0" "Cell type enhanced" "Detected in all" "Granulosa cells: 482.7;Hepatocytes: 220.6;Muller glia cells: 204.7;Theca cells: 204.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 38.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "MCF7: 69.2;RPTEC TERT1: 86.2;T-47d: 143.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030691, HPA072704" Enhanced Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 40: Granulosa cells - Unknown function" "Endoplasmic reticulum" Vesicles "HPA030691: AB_10602480, HPA072704: AB_2686551" "unprognostic (1.62e-1)" "unprognostic (5.23e-2)" "unprognostic (1.70e-2)" "unprognostic (1.78e-1)" "unprognostic (5.74e-2)" "unprognostic (1.10e-1)" "unprognostic (5.98e-2)" "unprognostic (6.06e-2)" "unprognostic (5.72e-2)" "unprognostic (1.74e-2)" "unprognostic (7.06e-2)" "unprognostic (1.69e-1)" "prognostic favorable (8.49e-8)" "unprognostic (8.77e-2)" "unprognostic (1.90e-1)" "unprognostic (1.35e-1)" "unprognostic (3.44e-2)" 63.4 246.0 27.8 2.6 28.5 4.1 29.1 32.8 33.9 17.4 64.1 7.8 9.4 3.4 17.0 39.6 12.8 7.0 47.3 30.0 29.7 18.9 86.4 10.1 3.4 34.0 32.0 36.5 69.9 36.3 19.5 3.9 32.5 41.1 3.9 6.0 46.9 6.0 7.1 68.2 8.3 1.9 30.1 5.1 35.6 11.5 32.6 5.6 15.5 3.7 8.4 5.5 22.1 35.1 7.7 10.9 27.3 35.1 8.1 1.3 15.4 1.8 4.5 2.7 3.0 26.0 35.8 16.3 26.9 2.2 1.0 13.3 11.6 21.2 1.9 16.7 5.0 10.2 2.7 54.5 18.8 4.2 10.6 3.7 5.0 14.6 3.9 12.6 3.9 28.7 5.8 13.9 0.8 69.2 8.3 18.6 12.6 18.4 11.2 22.4 1.2 39.9 86.2 12.6 27.2 30.5 1.2 28.2 6.1 19.5 143.9 11.4 3.1 0.4 3.4 3.8 2.3 27.1 18.1 8.4 2.5 5.9 1.0 1.1 1.6 3.4 9.1 1.5 7.0 12.4 5.6 7.8 1.5 11.9 11.8 9.0 1.1 12.5 0.9 38.1 5.6 4.9 27.8 28.5 32.8 33.9 30.0 29.7 34.0 32.0 32.5 30.1 32.6 35.1 4.0 9.6 43.7 23.5 12.7 1.9 6.2 33.6 5.7 19.2 52.2 38.5 99.4 52.9 36.6 44.1 10.4 72.9 16.3 23.3 17.6 27.1 28.8 17.9 2.6 5.7 59.4 13.7 11.6 27.7 4.6 4.3 31.1 16.5 7.0 482.7 5.0 220.6 15.6 25.2 15.3 21.8 52.9 6.3 2.7 59.3 9.9 5.8 12.4 2.8 9.4 204.7 7.2 17.1 36.5 21.7 23.7 2.2 12.9 31.3 29.0 77.5 37.9 23.6 13.1 1.6 21.8 13.3 17.9 18.0 7.0 82.1 8.3 204.8 19.0 10.4 TM9SF3 SMBP ENSG00000077147 "Transmembrane 9 superfamily member 3" Q9HD45 10 96518110-96587452 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039609 Approved Approved "Golgi apparatus,Vesicles" NA NA 240000 "Cluster 46: Basophils - DNA binding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 27: Mucus-secreting cells - Mucin production" Vesicles "Golgi apparatus" "HPA039609: AB_10673535" "unprognostic (3.33e-2)" "unprognostic (4.45e-2)" "unprognostic (1.43e-2)" "unprognostic (5.11e-2)" "unprognostic (4.95e-1)" "unprognostic (1.08e-2)" "unprognostic (1.16e-2)" "unprognostic (3.09e-2)" "unprognostic (1.14e-1)" "unprognostic (8.26e-2)" "unprognostic (4.14e-3)" "unprognostic (4.81e-2)" "unprognostic (2.25e-1)" "unprognostic (1.28e-1)" "unprognostic (2.48e-1)" "unprognostic (8.28e-3)" "unprognostic (6.18e-2)" 57.0 53.4 28.5 54.6 33.0 36.7 58.4 33.2 34.8 65.3 34.9 111.8 116.9 62.5 69.2 57.5 46.0 89.9 39.7 27.7 34.4 68.0 75.0 43.2 42.0 33.8 31.2 62.9 73.3 70.1 22.5 67.8 35.2 91.7 94.5 43.4 83.2 56.4 26.6 38.5 112.4 50.8 35.7 41.8 183.5 34.6 30.7 44.7 87.4 41.1 44.9 72.8 34.8 43.6 146.8 97.2 106.5 149.3 151.4 112.4 127.7 197.8 146.7 84.0 67.5 116.4 281.6 107.3 107.0 175.8 105.5 135.3 97.6 108.1 156.8 121.3 83.6 95.3 81.8 92.0 114.5 197.7 107.2 105.0 108.6 118.6 203.7 253.2 94.7 96.4 97.0 119.9 132.2 66.4 77.1 76.2 68.9 237.9 59.6 94.6 134.4 84.8 120.1 106.8 49.6 110.3 104.1 98.6 103.0 126.2 171.0 73.7 165.3 103.5 87.1 104.6 183.1 123.7 152.3 98.4 140.9 134.9 73.5 5.7 2.2 3.8 3.5 2.3 4.0 2.1 3.6 3.9 2.7 1.5 2.7 3.6 2.4 3.9 2.4 7.1 4.0 1.3 28.5 33.0 33.2 34.8 27.7 34.4 33.8 31.2 35.2 35.7 30.7 43.6 115.7 51.3 43.0 43.1 53.2 116.8 118.8 63.2 51.8 57.8 103.1 73.0 65.0 121.5 88.2 141.6 56.3 77.5 89.5 238.7 21.5 80.7 27.6 93.0 162.0 99.8 123.9 68.8 59.9 146.1 97.6 98.7 212.0 192.2 40.6 75.0 78.9 126.9 60.0 58.9 64.0 368.3 69.2 85.6 125.3 12.8 93.2 73.5 103.2 49.6 56.8 58.1 54.6 69.9 79.2 132.1 140.6 82.4 88.9 196.1 141.5 59.3 65.9 54.7 65.7 89.2 121.0 45.8 38.4 73.2 120.6 140.9 63.0 74.5 246.7 156.2 TMBIM1 "LFG3, PP1201, RECS1" ENSG00000135926 "Transmembrane BAX inhibitor motif containing 1" Q969X1 2 218274197-218292586 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 281.2;Pancreatic endocrine cells: 294.3;Syncytiotrophoblasts: 282.1;Urothelial cells: 299.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 573.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012093, HPA070824" Approved Supported Vesicles NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA012093: AB_1858056, HPA070824: AB_2686317" "unprognostic (4.36e-2)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (1.73e-3)" "unprognostic (2.34e-3)" "unprognostic (3.81e-3)" "unprognostic (8.91e-3)" "unprognostic (5.58e-3)" "unprognostic (9.85e-2)" "unprognostic (3.76e-3)" "prognostic unfavorable (4.22e-4)" "unprognostic (1.69e-1)" "prognostic favorable (3.38e-4)" "unprognostic (1.22e-1)" "unprognostic (4.63e-2)" "unprognostic (2.75e-2)" "unprognostic (4.50e-1)" 231.0 120.9 118.0 84.1 135.0 96.1 165.5 124.8 123.6 146.8 112.1 143.1 152.6 119.7 92.9 333.4 97.3 135.5 123.3 109.4 131.2 123.5 170.8 175.1 55.4 194.5 144.0 93.5 240.3 125.6 50.2 172.7 150.7 97.6 140.7 15.2 155.1 89.5 219.1 185.3 174.6 127.1 139.8 65.9 212.3 25.4 134.1 41.9 158.0 185.2 106.8 172.9 215.1 144.2 183.9 66.4 3.5 47.1 404.3 170.6 188.7 175.5 217.9 103.4 117.7 169.8 449.0 40.6 123.3 263.0 194.6 305.3 59.8 399.9 100.4 151.0 23.5 264.6 41.8 205.6 183.3 2.4 252.4 161.1 370.7 210.4 265.6 108.4 111.8 6.7 169.0 75.0 182.9 6.1 2.8 46.5 2.5 382.3 60.4 5.7 28.3 33.1 142.1 573.4 2.2 3.1 58.0 214.7 122.8 36.6 56.3 39.8 168.4 182.4 50.1 84.9 64.8 35.9 45.2 17.7 179.9 41.0 105.5 352.9 136.4 298.5 107.9 172.7 91.8 77.1 98.0 89.1 93.3 61.9 64.3 70.2 167.1 66.7 221.9 25.9 116.1 190.1 118.0 135.0 124.8 123.6 109.4 131.2 194.5 144.0 150.7 139.8 134.1 144.2 47.6 73.7 25.6 20.9 37.2 81.7 96.9 85.0 51.2 2.0 28.8 26.0 26.4 78.6 66.9 69.9 0.0 139.1 51.8 266.8 13.7 175.5 0.6 45.6 42.6 50.8 22.7 66.3 2.4 281.2 146.8 61.9 110.6 78.4 50.0 16.1 28.9 50.4 104.9 0.0 2.5 67.9 52.9 45.1 50.2 2.8 54.0 69.6 46.2 14.0 22.0 22.9 48.4 5.0 35.2 294.3 177.3 59.5 30.3 151.8 204.4 37.7 34.8 1.9 13.1 35.7 45.0 1.4 12.5 86.5 101.2 282.1 41.3 9.9 69.1 299.8 TMC4 ENSG00000167608 "Transmembrane channel like 4" 19 54160108-54173250 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "pancreas: 45.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 160.1;Paneth cells: 119.7;Proximal enterocytes: 228.6;Respiratory ciliated cells: 155.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "OE19: 17.3;T-47d: 30.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA048635 Approved Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 6: T47d - Mammary gland" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA048635: AB_2680470" "unprognostic (7.55e-2)" "unprognostic (1.66e-1)" "unprognostic (4.20e-2)" "unprognostic (1.49e-1)" "unprognostic (7.04e-2)" "unprognostic (1.68e-1)" "unprognostic (4.82e-2)" "unprognostic (2.19e-2)" "unprognostic (1.03e-1)" "unprognostic (2.68e-3)" "unprognostic (7.59e-2)" "unprognostic (3.09e-1)" "prognostic favorable (1.54e-8)" "unprognostic (6.70e-2)" "unprognostic (2.48e-1)" "unprognostic (8.94e-2)" "unprognostic (1.79e-2)" 2.3 0.4 0.2 0.4 0.2 0.0 12.5 0.3 0.7 8.7 0.0 38.6 33.1 3.2 0.0 14.8 16.8 8.4 5.7 0.3 0.2 25.5 2.6 11.9 0.1 0.5 0.8 1.1 45.6 4.5 21.0 0.7 0.7 21.6 12.0 0.0 42.1 4.9 1.4 5.4 37.2 0.4 0.2 0.2 31.9 0.5 0.2 0.0 31.3 0.1 0.5 18.9 9.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.8 0.1 0.1 0.4 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.1 0.0 17.3 0.0 0.1 0.0 0.7 0.5 0.0 0.0 0.0 0.0 1.3 0.0 0.0 30.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.7 0.3 0.2 0.5 0.8 0.7 0.2 0.2 0.1 1.5 28.9 30.0 0.7 1.5 2.4 26.9 78.6 24.5 0.3 42.5 19.8 1.7 51.5 94.4 46.0 0.0 22.7 3.7 160.1 13.7 78.2 0.0 59.7 6.6 2.2 41.6 0.0 0.6 64.1 6.1 1.8 102.4 56.2 5.7 0.5 1.1 0.6 3.9 0.0 0.6 92.7 57.0 1.3 3.0 0.1 1.2 3.2 1.8 0.0 2.1 0.1 4.1 1.0 0.7 50.7 119.7 0.7 2.4 22.0 228.6 29.0 155.7 0.5 26.3 0.9 13.6 0.4 1.9 22.0 1.7 23.4 2.8 2.1 77.1 43.1 TMC7 FLJ21240 ENSG00000170537 "Transmembrane channel like 7" Q7Z402 16 18983934-19063942 "Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.9;testis: 9.6" "Group enriched" "Detected in many" 6 "Early spermatids: 172.0;Late spermatids: 44.6;Oligodendrocytes: 96.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029465 Uncertain Approved Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA029465: AB_10600914" "unprognostic (1.80e-4)" "unprognostic (6.13e-2)" "unprognostic (1.82e-1)" "unprognostic (2.07e-3)" "unprognostic (1.25e-1)" "unprognostic (1.19e-3)" "unprognostic (7.60e-5)" "prognostic unfavorable (3.20e-4)" "unprognostic (7.60e-2)" "unprognostic (1.29e-1)" "prognostic unfavorable (7.64e-4)" "unprognostic (3.39e-1)" "unprognostic (1.00e-1)" "unprognostic (1.75e-1)" "unprognostic (1.94e-1)" "unprognostic (5.66e-2)" "prognostic favorable (9.20e-4)" 2.1 0.2 6.0 1.0 15.8 0.3 1.7 12.4 10.6 0.5 0.4 3.8 2.5 0.7 0.6 0.4 0.4 1.4 1.4 7.0 9.0 0.6 0.3 2.9 0.3 13.8 13.2 0.2 0.4 0.4 0.3 4.3 12.6 1.5 4.5 1.1 0.4 0.9 0.9 1.1 2.7 1.1 7.5 0.6 3.1 9.6 15.0 0.2 0.8 0.9 0.2 8.1 0.8 23.9 1.9 3.5 1.0 1.9 0.2 1.6 4.8 0.6 1.0 0.7 1.5 1.2 8.5 0.2 7.9 0.7 1.8 6.8 2.9 2.8 0.9 0.1 2.0 0.1 3.6 5.5 0.2 0.2 0.1 0.3 4.1 6.5 7.2 2.2 2.6 3.8 2.2 0.2 2.8 3.9 0.3 0.3 3.1 11.1 5.1 0.2 3.1 0.2 1.3 8.7 0.6 1.9 2.1 5.4 0.6 4.9 1.7 0.6 2.3 1.1 1.8 1.3 3.3 0.4 0.9 0.2 5.4 0.3 1.0 0.7 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.2 0.1 0.1 0.5 0.3 0.1 0.2 0.1 0.0 6.0 15.8 12.4 10.6 7.0 9.0 13.8 13.2 12.6 7.5 15.0 23.9 12.6 3.2 6.2 3.9 0.1 0.4 4.4 3.2 0.0 0.6 1.3 0.4 0.7 1.5 2.0 0.0 0.0 0.2 0.0 13.4 0.0 4.1 172.0 1.4 0.4 4.9 1.2 2.7 7.5 11.0 2.3 0.6 9.2 2.4 0.0 1.2 4.6 0.2 0.2 0.0 12.1 6.0 4.1 0.0 1.2 44.6 1.2 0.6 0.0 6.5 0.2 0.3 2.1 6.6 96.5 14.0 8.0 0.4 0.1 2.3 3.6 0.3 0.9 2.7 0.0 1.6 2.2 6.9 12.1 1.9 1.0 0.3 0.4 0.1 7.6 17.3 TMCC3 KIAA1145 ENSG00000057704 "Transmembrane and coiled-coil domain family 3" Q9ULS5 12 94567122-94650557 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.3" "Cell type enhanced" "Detected in many" "Adipocytes: 81.2;Distal enterocytes: 98.3;Microglial cells: 70.3;Oligodendrocytes: 119.8;Paneth cells: 70.1;Urothelial cells: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 46.9;neutrophil: 69.7" "Lineage enriched" "Detected in all" 9 "granulocytes: 69.7" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 31.3;Karpas-707: 41.9;U-266/84: 30.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014272 Approved Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" Vesicles "HPA014272: AB_1858059" "unprognostic (1.03e-1)" "unprognostic (2.54e-1)" "unprognostic (1.52e-3)" "prognostic unfavorable (4.87e-4)" "unprognostic (1.30e-1)" "unprognostic (8.63e-2)" "unprognostic (5.87e-2)" "unprognostic (1.17e-2)" "unprognostic (9.12e-2)" "unprognostic (3.45e-3)" "unprognostic (1.24e-1)" "unprognostic (7.73e-2)" "unprognostic (1.80e-3)" "unprognostic (9.11e-2)" "unprognostic (2.32e-1)" "unprognostic (5.41e-2)" "unprognostic (4.75e-2)" 11.7 4.5 13.6 9.4 25.8 10.0 9.6 23.1 16.5 11.6 3.9 22.5 14.9 7.7 3.1 6.1 5.7 5.3 2.3 13.2 19.6 8.1 4.1 5.3 4.4 26.9 25.9 4.7 3.2 4.6 3.4 17.8 26.7 8.3 16.4 0.9 2.8 5.4 18.4 6.1 21.0 7.9 20.8 12.2 7.3 2.0 24.8 4.0 13.3 7.0 6.3 7.5 4.8 36.3 7.8 0.4 1.9 0.0 0.7 2.7 13.6 0.0 0.0 0.5 1.9 0.0 1.7 0.2 0.1 0.0 6.8 19.1 10.7 12.9 2.6 3.5 2.6 5.1 0.8 0.0 0.5 0.0 10.2 1.7 1.7 7.2 10.1 11.3 31.3 0.0 0.2 41.9 1.0 0.4 0.0 0.4 1.0 2.7 6.5 0.0 0.6 5.1 2.0 16.4 0.2 0.8 0.2 8.0 0.4 8.8 0.0 0.4 19.0 0.0 0.2 0.1 3.4 19.4 30.1 0.3 3.9 1.6 1.7 16.4 4.3 46.9 3.3 6.0 0.3 5.4 1.2 1.9 2.5 3.1 0.0 2.2 69.7 3.3 7.8 2.8 0.0 3.1 13.6 25.8 23.1 16.5 13.2 19.6 26.9 25.9 26.7 20.8 24.8 36.3 81.2 0.0 2.7 2.9 5.7 20.6 32.7 3.2 9.6 4.4 2.1 1.3 2.0 4.3 3.2 7.3 0.0 16.0 16.3 98.3 0.0 1.9 5.8 24.5 3.6 31.9 12.0 0.0 0.6 3.8 3.2 4.8 10.2 39.8 0.0 17.1 31.8 0.6 4.1 0.0 15.0 13.0 0.0 15.0 9.2 8.3 1.8 20.3 3.6 70.3 19.0 0.1 11.3 11.6 119.8 12.9 70.1 1.2 7.8 16.8 48.1 8.9 3.0 0.3 6.6 19.7 6.1 0.0 2.2 30.4 16.2 7.1 7.7 2.5 8.2 83.3 TMED2 "P24A, p24b1, p24beta1, RNP24" ENSG00000086598 "Transmembrane p24 trafficking protein 2" Q15363 12 123584533-123598582 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014060 Approved Supported Vesicles NA NA 82000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "HPA014060: AB_1856389" "unprognostic (6.36e-2)" "unprognostic (3.38e-3)" "unprognostic (5.41e-3)" "unprognostic (1.75e-2)" "unprognostic (2.98e-2)" "prognostic unfavorable (3.36e-6)" "unprognostic (3.57e-3)" "unprognostic (2.20e-2)" "unprognostic (4.31e-2)" "unprognostic (9.76e-3)" "unprognostic (1.03e-2)" "unprognostic (3.94e-2)" "prognostic unfavorable (2.35e-7)" "unprognostic (2.97e-1)" "unprognostic (1.63e-1)" "unprognostic (1.51e-1)" "unprognostic (9.87e-2)" 106.0 97.1 40.7 92.6 43.5 122.1 136.1 44.2 50.8 155.6 59.5 132.5 123.7 102.5 203.3 111.9 102.3 96.1 116.5 40.5 45.3 102.8 271.1 85.4 72.7 46.6 46.6 101.5 229.1 99.3 65.0 125.4 46.9 140.5 140.7 56.9 227.6 102.2 131.0 74.8 110.5 102.1 46.0 63.2 133.8 58.5 44.2 69.1 197.6 112.1 95.2 118.6 71.4 53.8 237.7 204.9 133.4 232.2 295.7 260.2 317.5 401.2 318.5 246.8 194.2 209.9 198.9 199.3 210.7 398.7 169.4 228.1 181.8 214.5 257.3 155.2 169.3 217.3 114.0 267.6 559.5 296.9 178.1 220.5 349.2 212.6 286.0 352.7 234.7 133.5 223.1 132.9 255.6 175.1 159.8 242.7 192.9 201.0 206.6 164.8 216.8 235.7 303.9 349.1 166.5 143.1 267.3 263.6 273.7 160.0 450.2 237.2 226.2 210.1 132.4 204.9 227.5 292.3 290.7 167.6 248.3 192.9 254.2 249.7 143.2 145.9 157.0 147.5 198.8 111.8 137.0 148.4 158.6 102.5 110.3 129.4 111.1 148.5 141.3 242.5 140.1 142.2 40.7 43.5 44.2 50.8 40.5 45.3 46.6 46.6 46.9 46.0 44.2 53.8 97.1 48.1 71.5 9.1 148.8 417.4 290.3 348.5 207.1 50.1 258.8 98.0 167.2 213.1 233.2 154.5 20.9 281.5 166.9 169.6 117.4 325.1 12.2 89.2 136.5 142.0 170.7 76.3 20.0 249.6 678.6 242.7 156.5 136.8 92.6 88.4 143.5 538.8 215.8 48.8 20.3 352.4 321.4 141.7 414.3 13.9 181.4 128.5 378.8 17.8 129.8 124.1 195.7 19.6 27.5 224.9 158.5 153.4 521.0 486.3 178.1 163.0 142.1 54.7 164.3 112.6 193.5 165.9 150.6 289.8 498.8 451.9 154.3 125.0 263.9 389.2 TMED8 FAM15B ENSG00000100580 "Transmembrane p24 trafficking protein family member 8" Q6PL24 14 77335029-77377094 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 62.7;Cone photoreceptor cells: 108.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Daudi: 58.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001205 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" Vesicles "HPA001205: AB_2204460" "unprognostic (1.07e-1)" "unprognostic (4.70e-2)" "unprognostic (4.85e-2)" "unprognostic (2.39e-1)" "unprognostic (1.13e-1)" "unprognostic (7.82e-2)" "unprognostic (1.68e-2)" "unprognostic (3.74e-2)" "unprognostic (1.22e-1)" "unprognostic (2.01e-1)" "unprognostic (2.81e-2)" "unprognostic (1.04e-1)" "unprognostic (1.03e-3)" "unprognostic (2.23e-3)" "unprognostic (1.12e-1)" "unprognostic (5.88e-2)" "unprognostic (2.77e-1)" 5.5 8.3 8.2 8.6 9.6 7.7 5.7 4.7 8.4 5.9 4.1 4.4 3.3 6.7 5.1 3.6 5.4 4.1 3.4 7.5 16.6 10.4 3.4 4.6 17.5 7.9 10.5 7.3 5.6 11.1 9.2 4.4 11.2 5.9 4.8 24.2 4.4 5.9 2.3 4.9 5.5 5.6 6.9 8.0 6.2 6.8 12.8 9.8 10.9 2.4 19.5 4.7 3.5 5.9 14.7 12.0 13.9 12.4 8.5 7.6 11.8 9.2 6.0 9.4 10.1 7.5 8.1 58.7 7.5 7.5 7.7 10.0 10.4 10.5 14.6 18.6 6.3 19.6 9.5 7.9 5.9 9.6 51.8 8.0 7.4 12.3 11.0 9.5 13.5 47.7 10.1 15.4 9.5 14.4 15.2 14.2 6.9 10.7 12.0 12.2 12.7 4.7 9.9 9.0 17.2 10.4 15.9 9.4 11.8 10.6 15.2 15.9 9.7 9.7 6.2 17.5 10.7 12.3 25.2 28.9 11.1 17.7 14.3 2.3 0.7 2.2 0.3 0.9 0.4 2.1 0.5 0.4 0.6 2.1 0.3 0.5 1.0 0.5 0.8 1.0 0.7 0.5 8.2 9.6 4.7 8.4 7.5 16.6 7.9 10.5 11.2 6.9 12.8 5.9 6.6 3.2 7.8 62.7 33.9 6.6 4.9 7.7 2.8 33.4 12.5 8.3 16.8 8.6 5.3 22.0 108.4 10.5 7.9 6.5 5.9 6.4 4.8 9.8 15.5 10.4 44.3 15.4 44.7 4.7 10.0 8.4 7.1 9.0 0.0 9.1 8.9 9.8 7.8 28.6 40.7 6.3 10.2 24.8 7.7 6.9 14.6 19.8 5.4 21.5 16.8 14.9 6.2 39.7 24.2 6.8 3.3 14.3 19.9 7.5 3.2 22.2 20.9 39.3 13.1 7.1 8.4 6.8 15.7 8.2 8.9 4.1 10.3 19.8 6.7 4.3 TMEM102 "CBAP, FLJ36878" ENSG00000181284 "Transmembrane protein 102" Q8N9M5 17 7435435-7437679 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 69.0;Pancreatic endocrine cells: 32.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 3.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 10.6;HMC-1: 11.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA024433 Uncertain Approved Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "HPA024433: AB_1858071" "unprognostic (2.42e-2)" "unprognostic (2.52e-2)" "unprognostic (1.54e-2)" "unprognostic (1.64e-1)" "unprognostic (1.10e-2)" "unprognostic (9.24e-2)" "unprognostic (2.46e-1)" "unprognostic (1.61e-1)" "unprognostic (2.91e-2)" "unprognostic (2.69e-2)" "unprognostic (2.69e-1)" "unprognostic (4.95e-2)" "prognostic favorable (9.90e-4)" "unprognostic (1.10e-3)" "unprognostic (8.40e-2)" "unprognostic (1.67e-1)" "unprognostic (1.42e-3)" 2.6 8.1 0.4 1.5 0.6 1.5 3.4 0.7 0.3 3.2 0.2 5.9 2.8 1.8 1.0 10.2 1.7 1.0 2.0 0.3 0.3 5.2 4.4 3.1 2.5 0.7 0.6 0.5 5.4 1.6 1.0 0.8 0.6 2.3 1.0 0.2 6.2 0.7 3.6 8.8 6.0 0.3 0.5 6.4 4.4 6.7 0.6 1.5 3.8 0.1 1.8 2.6 4.6 0.6 5.3 3.7 0.4 0.0 1.3 0.6 2.9 1.1 1.4 0.7 1.5 2.0 5.5 5.3 4.8 0.5 0.7 10.6 0.9 5.8 0.1 4.8 6.5 4.9 2.2 1.9 0.6 2.9 11.9 0.4 5.4 0.4 1.0 1.8 2.4 4.5 1.9 0.3 0.0 3.2 3.3 5.2 0.2 5.1 3.0 5.4 0.4 1.9 5.0 3.4 0.2 3.4 0.6 4.7 1.4 0.9 2.5 1.2 3.2 0.2 0.3 0.6 0.1 1.0 1.4 0.7 1.6 2.5 2.4 0.0 0.4 3.8 0.7 0.9 0.4 0.8 0.8 0.9 0.5 0.8 0.6 0.6 0.0 1.0 1.0 0.5 0.7 0.4 0.4 0.6 0.7 0.3 0.3 0.3 0.7 0.6 0.6 0.5 0.6 0.6 2.4 0.0 0.0 0.0 8.8 3.7 5.6 5.2 8.6 0.0 4.0 3.4 1.1 7.2 4.2 1.8 0.0 9.1 6.5 18.2 7.9 21.6 16.8 7.1 1.1 3.0 1.2 2.5 0.1 21.9 7.9 0.4 9.7 11.0 0.0 4.5 2.2 3.6 7.1 1.7 0.1 8.2 6.1 7.2 10.6 69.0 0.9 4.5 1.8 0.0 11.6 1.6 8.2 0.0 0.5 32.5 15.3 0.7 5.9 2.9 15.2 9.0 2.4 0.6 0.0 0.4 1.4 1.1 2.7 5.7 7.1 5.1 8.1 0.6 7.6 13.1 TMEM108 "CT124, MGC3040" ENSG00000144868 "Transmembrane protein 108" Q6UXF1 3 133038391-133397775 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 35.2;skeletal muscle: 23.1" "Cell type enhanced" "Detected in many" "Astrocytes: 209.9;Excitatory neurons: 357.3;Inhibitory neurons: 475.3;Oligodendrocyte precursor cells: 480.0" "Cancer enhanced" "Detected in many" "glioma: 4.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 24.2;LHCN-M2: 13.8;SCLC-21H: 21.0;SH-SY5Y: 92.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063350 Enhanced Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 55000 "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nucleoli, Vesicles" "HPA063350: AB_2684993" "unprognostic (4.75e-2)" "unprognostic (1.73e-2)" "unprognostic (9.00e-2)" "unprognostic (1.92e-2)" "unprognostic (3.07e-3)" "unprognostic (3.17e-1)" "unprognostic (1.28e-1)" "unprognostic (3.65e-2)" "unprognostic (2.06e-4)" "unprognostic (2.08e-1)" "unprognostic (7.27e-4)" "unprognostic (1.11e-1)" "unprognostic (3.03e-4)" "unprognostic (1.60e-3)" "unprognostic (1.61e-2)" "unprognostic (6.12e-2)" "unprognostic (1.36e-2)" 1.4 11.3 6.3 1.5 9.6 0.2 1.5 3.4 10.0 2.0 3.2 1.5 0.4 2.4 0.6 9.6 1.7 0.8 6.8 9.6 2.9 0.4 0.1 11.0 1.7 0.0 4.1 0.3 0.3 3.0 2.2 2.4 4.0 1.0 1.3 35.2 1.3 2.0 23.1 1.4 1.6 5.5 0.0 1.3 1.3 13.9 7.9 1.3 3.1 7.0 2.3 8.3 0.8 0.8 0.0 0.0 4.1 0.0 0.0 0.1 0.0 0.2 0.0 1.1 0.0 0.3 0.0 0.1 1.0 0.0 0.0 0.1 0.2 0.0 0.7 1.0 1.8 8.5 0.0 0.0 0.0 0.0 24.2 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.1 13.8 0.7 0.1 0.3 3.8 0.0 0.0 0.0 4.8 0.1 1.1 0.0 21.0 92.6 0.0 0.1 0.3 5.5 0.2 0.0 0.0 0.1 0.1 0.0 3.4 1.3 0.0 0.7 1.8 0.0 3.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 9.6 3.4 10.0 9.6 2.9 0.0 4.1 4.0 0.0 7.9 0.8 0.6 3.2 4.6 209.9 0.0 2.4 0.5 0.2 0.0 10.4 1.3 2.8 1.7 1.5 5.0 0.0 102.2 1.8 0.0 0.0 0.0 0.0 80.6 1.0 0.6 1.3 0.0 0.0 357.3 0.4 8.6 4.6 4.1 0.2 1.3 5.5 0.4 0.0 0.3 1.7 475.3 0.0 0.0 0.0 0.8 38.2 0.9 0.1 0.0 33.7 0.0 5.7 0.0 480.0 22.2 0.3 0.0 0.7 1.2 0.2 0.0 0.0 0.0 57.6 0.0 6.8 3.3 17.2 11.2 0.0 1.6 1.1 1.0 4.9 0.0 0.4 TMEM121B CECR6 ENSG00000183307 "Transmembrane protein 121B" Q9BXQ6 22 17116297-17121367 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.7;prostate: 6.6" "Cell type enhanced" "Detected in some" "granulocytes: 1.3;Hofbauer cells: 2.8" "Cancer enhanced" "Detected in some" "prostate cancer: 6.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;neutrophil: 1.6" "Group enriched" "Detected in many" 7 "granulocytes: 1.6;monocytes: 1.1" "Cell line enhanced" "Detected in some" "AF22: 6.0;SCLC-21H: 14.2;THP-1: 11.9;U-937: 9.8" "Low region specificity" "Detected in all" HPA068790 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Nucleoplasm, Plasma membrane" "HPA068790: AB_2686036" "unprognostic (2.30e-1)" "unprognostic (1.05e-1)" "unprognostic (7.11e-3)" "unprognostic (4.49e-3)" "unprognostic (3.36e-1)" "unprognostic (7.14e-3)" "unprognostic (1.12e-3)" "unprognostic (5.32e-2)" "unprognostic (1.97e-1)" "unprognostic (2.01e-2)" "unprognostic (6.88e-4)" "unprognostic (6.08e-2)" "unprognostic (3.10e-4)" "unprognostic (1.02e-2)" "unprognostic (4.37e-2)" "unprognostic (3.49e-3)" "unprognostic (1.71e-1)" 0.3 0.6 6.4 0.9 7.5 1.0 0.7 3.5 7.6 0.2 1.5 0.2 0.2 0.3 0.9 0.3 0.3 0.2 1.2 8.7 3.9 0.3 0.1 0.3 0.1 3.8 3.3 0.2 1.1 0.1 1.6 0.7 3.3 6.6 0.2 1.3 0.4 0.2 1.3 0.5 0.2 0.3 3.6 0.7 0.2 1.9 4.9 0.1 0.1 0.4 0.1 0.3 0.2 5.1 0.0 0.0 6.0 0.8 0.0 0.0 0.0 0.1 0.1 0.2 0.4 0.2 0.0 0.2 0.1 0.0 0.2 0.0 0.7 0.0 0.2 0.1 0.9 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.1 0.1 0.3 0.0 0.8 3.2 2.1 0.0 0.1 0.2 3.0 0.0 0.3 0.1 14.2 2.1 0.0 0.0 0.3 0.8 0.0 11.9 0.6 0.6 0.2 0.2 0.0 0.2 0.4 0.9 0.0 9.8 0.3 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.2 6.4 7.5 3.5 7.6 8.7 3.9 3.8 3.3 3.3 3.6 4.9 5.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 1.3 0.9 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 TMEM123 "KCT3, PORIMIN" ENSG00000152558 "Transmembrane protein 123" Q8N131 11 102396332-102470384 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 988.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026001, HPA062862" Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 32: Non-specific - Translation" "Golgi apparatus" "Vesicles, Cytosol" "CAB026001: , HPA062862: AB_2732691" "unprognostic (2.64e-1)" "unprognostic (8.39e-2)" "unprognostic (4.18e-3)" "unprognostic (1.40e-1)" "unprognostic (7.32e-2)" "unprognostic (2.33e-1)" "unprognostic (9.91e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.36e-4)" "unprognostic (3.08e-1)" "prognostic unfavorable (2.66e-4)" "unprognostic (1.67e-1)" "unprognostic (1.38e-2)" "unprognostic (8.10e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-2)" "unprognostic (3.65e-2)" 56.0 80.2 53.0 120.2 60.3 225.1 153.3 56.7 68.2 114.9 67.0 120.0 63.5 174.7 47.8 100.1 91.7 99.6 71.2 48.0 61.0 93.2 393.7 119.2 196.4 71.2 68.6 86.8 82.5 70.7 15.8 98.5 65.1 105.2 97.1 9.2 224.0 104.1 20.4 95.6 78.8 130.6 61.3 111.2 125.5 73.3 61.5 238.6 312.3 49.7 142.9 146.8 70.7 89.8 220.5 195.8 186.9 174.8 233.5 185.6 135.8 169.7 352.0 324.4 358.1 247.9 988.1 370.2 423.9 387.9 234.5 228.3 212.3 272.9 339.4 228.4 82.5 192.0 67.8 352.3 207.5 404.1 137.4 219.1 280.7 240.1 352.3 433.9 361.8 187.8 134.3 0.9 257.7 71.8 353.0 135.4 115.8 340.3 181.1 214.7 532.0 359.3 291.3 207.9 90.7 110.5 201.8 267.6 109.9 197.2 161.3 154.0 451.9 211.3 249.4 190.5 126.6 139.4 84.3 366.6 62.0 432.7 143.2 159.7 113.3 207.0 102.6 121.8 155.3 70.1 158.8 123.8 126.1 95.3 208.6 181.7 72.4 223.9 111.0 33.7 183.8 248.7 53.0 60.3 56.7 68.2 48.0 61.0 71.2 68.6 65.1 61.3 61.5 89.8 93.3 125.0 78.1 33.0 179.3 160.3 257.1 307.3 157.6 0.7 144.9 118.4 53.9 143.0 202.8 163.7 0.0 45.8 91.8 48.2 80.3 153.7 41.3 141.1 47.6 140.0 90.5 68.3 1.0 118.8 41.1 82.2 88.2 161.4 58.9 126.6 271.3 317.6 107.1 1.7 2.2 163.1 160.7 249.6 419.9 23.6 94.1 189.8 161.9 63.7 229.4 4.7 83.4 25.6 114.0 127.8 55.1 93.3 117.8 324.2 31.0 52.9 257.0 1.1 65.7 181.9 80.2 23.1 74.9 146.3 177.2 30.4 164.8 109.4 146.3 270.2 TMEM131 "CC28, KIAA0257, PRO1048, RW1, YR-23" ENSG00000075568 "Transmembrane protein 131" Q92545 2 97756333-97995948 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 129.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017678, HPA017682" Approved Uncertain "Vesicles,Intermediate filaments" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" "Vesicles, Intermediate filaments" "HPA017678: AB_1858086, HPA017682: AB_1858087" "unprognostic (1.16e-2)" "unprognostic (1.39e-1)" "unprognostic (1.04e-1)" "unprognostic (7.42e-2)" "unprognostic (8.58e-2)" "unprognostic (4.18e-2)" "unprognostic (7.59e-3)" "unprognostic (3.26e-1)" "unprognostic (1.53e-1)" "unprognostic (3.78e-2)" "unprognostic (1.61e-1)" "unprognostic (1.06e-1)" "unprognostic (5.10e-3)" "unprognostic (5.37e-2)" "unprognostic (1.43e-1)" "unprognostic (2.72e-1)" "unprognostic (1.77e-1)" 12.1 12.2 7.2 20.7 7.5 17.5 10.6 7.2 7.6 18.8 9.3 25.8 18.5 16.3 8.5 14.3 15.3 15.8 13.0 7.4 5.5 12.1 13.5 12.4 25.4 6.1 7.5 16.3 19.0 27.5 11.1 18.3 6.1 16.6 23.2 11.4 13.4 11.5 24.4 24.1 19.4 16.5 6.6 18.4 26.2 14.7 10.3 18.4 12.8 22.3 23.1 14.1 10.4 8.6 26.1 15.7 28.8 21.0 29.6 35.8 31.4 37.8 36.5 18.9 22.7 20.3 36.8 41.3 20.4 39.3 32.2 18.4 30.5 50.5 28.0 29.4 19.8 30.0 10.6 29.3 33.4 28.2 38.6 34.4 20.2 33.7 34.7 32.0 23.5 19.8 18.1 42.8 58.2 15.7 20.6 17.9 15.8 20.2 33.4 29.7 18.3 18.3 19.3 30.7 32.3 15.7 24.4 16.7 23.2 30.7 14.0 25.8 28.1 49.1 22.4 23.9 14.7 18.1 26.8 20.6 38.5 24.3 33.9 3.7 1.3 3.6 1.7 1.6 1.9 2.1 1.5 1.7 1.7 1.9 1.7 2.3 0.9 2.5 1.6 2.4 1.0 1.0 7.2 7.5 7.2 7.6 7.4 5.5 6.1 7.5 6.1 6.6 10.3 8.6 29.4 16.0 27.9 90.1 41.2 19.8 17.7 16.3 24.5 28.3 17.3 16.0 34.7 15.7 23.4 20.2 22.9 15.4 33.1 62.2 3.9 9.7 14.4 88.9 33.9 19.3 30.1 23.5 113.1 24.0 12.7 23.5 60.1 86.8 23.5 21.3 22.9 26.0 24.5 25.2 99.7 45.6 10.2 29.2 18.5 20.1 20.8 35.8 12.4 87.1 47.0 14.1 9.2 92.5 129.8 18.1 40.1 19.2 36.3 17.9 27.4 7.0 38.2 19.3 13.1 31.9 24.9 21.2 26.0 25.0 25.6 13.5 22.4 28.0 36.6 16.0 TMEM131L "DKFZp586H1322, KIAA0922" ENSG00000121210 "Transmembrane 131 like" A2VDJ0 4 153466346-153636711 "Predicted membrane proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 49.4;lymphoid tissue: 48.3" "Cell type enhanced" "Detected in many" "Adipocytes: 13.6;Alveolar cells type 2: 9.6;B-cells: 9.9;dendritic cells: 13.2;Exocrine glandular cells: 9.3;monocytes: 16.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 105.2;MOLT-4: 99.9;U-698: 122.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043472, HPA048443" Uncertain Approved "Nucleoli fibrillar center,Vesicles" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles "Nucleoli fibrillar center" "HPA043472: AB_2678496, HPA048443: AB_2680395" "unprognostic (1.12e-1)" "prognostic favorable (6.69e-6)" "unprognostic (1.71e-1)" "unprognostic (3.75e-2)" "unprognostic (8.37e-2)" "unprognostic (1.34e-2)" "unprognostic (1.90e-2)" "unprognostic (3.30e-2)" "unprognostic (3.23e-2)" "unprognostic (4.11e-2)" "unprognostic (4.37e-2)" "unprognostic (7.29e-2)" "unprognostic (4.35e-3)" "unprognostic (2.92e-2)" "unprognostic (3.39e-2)" "unprognostic (3.94e-2)" "unprognostic (3.51e-2)" 9.8 1.7 1.6 20.9 4.0 49.4 7.2 1.0 2.7 5.6 1.0 6.4 2.3 6.3 9.4 6.7 5.0 4.9 8.7 1.5 1.6 3.5 20.7 6.6 47.8 1.9 1.4 4.6 31.2 1.1 3.9 3.9 1.9 5.9 4.6 0.4 8.1 4.8 24.5 6.9 10.9 6.9 1.0 24.6 6.1 4.4 2.0 48.3 4.1 6.2 45.4 6.1 6.0 2.8 5.8 3.7 15.7 16.5 9.1 7.9 0.3 8.3 4.0 5.6 7.1 25.8 3.7 105.2 2.0 11.1 6.2 5.7 12.1 14.3 8.5 9.7 8.7 20.6 7.0 6.7 5.9 22.9 1.2 7.3 8.7 7.4 6.9 6.3 14.4 19.1 19.7 0.4 5.7 10.7 99.9 16.6 14.0 0.2 5.4 34.3 15.2 6.8 3.8 2.4 11.7 9.1 6.5 14.2 8.6 8.0 5.5 16.6 11.6 7.5 13.2 9.1 6.9 11.2 12.1 122.4 2.2 13.5 6.2 11.8 19.4 21.1 12.3 36.8 16.7 28.2 15.5 11.7 20.9 27.3 25.8 17.5 21.0 24.3 31.6 2.1 20.9 17.6 1.6 4.0 1.0 2.7 1.5 1.6 1.9 1.4 1.9 1.0 2.0 2.8 13.6 6.4 9.6 0.0 9.9 0.0 0.0 0.0 0.0 0.0 5.5 4.3 0.0 0.0 1.8 0.0 0.0 0.5 13.2 0.0 1.9 2.0 0.0 1.3 8.2 3.2 0.0 0.0 0.0 9.3 0.2 3.7 0.0 1.1 5.1 5.8 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 16.1 0.0 0.0 0.0 0.0 3.6 0.0 0.0 4.8 0.0 0.0 1.5 5.8 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 7.2 5.1 0.0 0.0 TMEM135 FLJ22104 ENSG00000166575 "Transmembrane protein 135" Q86UB9 11 87037844-87328824 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 121.8;Excitatory neurons: 99.6;Inhibitory neurons: 93.7;Oligodendrocyte precursor cells: 123.1;Oligodendrocytes: 202.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Hep G2: 88.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056685, HPA069473" Uncertain Supported Vesicles NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA056685: AB_2683208, HPA069473: AB_2686139" "unprognostic (1.55e-2)" "unprognostic (1.11e-1)" "unprognostic (2.70e-2)" "unprognostic (6.51e-2)" "unprognostic (3.10e-2)" "unprognostic (4.42e-1)" "unprognostic (1.45e-2)" "unprognostic (2.63e-1)" "unprognostic (2.19e-1)" "unprognostic (1.13e-1)" "unprognostic (2.26e-1)" "unprognostic (1.65e-1)" "prognostic favorable (9.02e-4)" "unprognostic (3.48e-2)" "unprognostic (7.34e-2)" "unprognostic (1.35e-2)" "unprognostic (1.80e-1)" 26.1 14.9 4.2 5.6 6.0 3.7 14.2 2.8 5.2 5.6 5.8 10.5 15.6 6.4 4.7 4.4 6.0 8.3 6.7 4.9 5.2 12.0 24.7 6.5 5.9 5.0 5.8 7.3 6.2 9.4 5.4 10.2 5.6 10.7 8.5 7.0 10.0 6.4 8.4 3.9 14.5 6.9 2.5 5.8 7.4 10.2 4.3 6.6 10.1 7.5 4.8 5.5 4.4 6.7 8.8 15.7 9.8 13.7 31.3 28.6 9.2 6.5 16.7 7.6 17.0 27.1 39.9 24.2 17.1 8.9 19.9 8.3 13.3 14.9 8.5 22.7 7.5 18.5 14.0 88.5 17.6 10.8 9.2 34.8 9.2 11.0 7.6 10.2 19.5 26.4 19.3 35.9 9.0 5.9 28.3 10.8 11.5 47.2 11.7 12.5 7.5 19.2 17.5 28.1 4.8 11.0 9.6 30.0 13.6 18.8 42.0 9.6 10.3 7.9 10.3 30.6 4.6 13.4 28.2 28.2 6.0 11.5 15.7 0.9 4.8 1.4 7.5 5.1 6.7 4.7 4.7 8.1 5.6 3.4 5.3 5.1 1.5 7.2 2.2 5.7 5.4 4.1 4.2 6.0 2.8 5.2 4.9 5.2 5.0 5.8 5.6 2.5 4.3 6.7 14.4 9.6 7.5 121.8 7.1 4.2 4.0 4.6 8.6 5.6 12.7 7.1 6.3 5.7 6.8 1.8 4.2 2.6 7.7 10.5 5.9 2.8 2.8 5.8 11.0 8.1 3.6 3.8 99.6 3.2 8.6 11.0 8.6 4.2 9.5 11.5 7.9 16.2 4.9 1.7 93.7 6.8 10.2 7.8 6.0 7.7 7.2 5.4 5.4 48.7 4.1 5.0 9.2 123.1 202.4 3.1 10.9 7.2 10.3 6.1 21.8 10.6 8.7 4.2 32.9 5.7 8.4 2.2 3.8 4.8 4.8 1.5 8.3 24.6 8.7 3.8 TMEM145 FLJ90805 ENSG00000167619 "Transmembrane protein 145" Q8NBT3 19 42313309-42325064 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "brain: 67.8;pituitary gland: 18.3;retina: 28.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 64.5;Cone photoreceptor cells: 29.2;Excitatory neurons: 26.5;Horizontal cells: 69.0;Inhibitory neurons: 54.3;Rod photoreceptor cells: 33.0" "Cancer enriched" "Detected in many" 5 "glioma: 8.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "basophil: 6.8;neutrophil: 14.2" "Lineage enriched" "Detected in many" 11 "granulocytes: 14.2" "Cell line enhanced" "Detected in many" "HMC-1: 13.7;PC-3: 11.6;SCLC-21H: 26.2;SH-SY5Y: 12.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060462 Enhanced Approved Approved Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Vesicles "HPA060462: AB_2684285" "unprognostic (9.56e-3)" "unprognostic (8.61e-2)" "unprognostic (6.65e-2)" "unprognostic (1.19e-1)" "unprognostic (2.96e-1)" "unprognostic (3.02e-1)" "unprognostic (1.47e-1)" "unprognostic (6.62e-2)" "unprognostic (2.14e-1)" "unprognostic (4.27e-3)" "unprognostic (1.53e-2)" "unprognostic (9.85e-2)" "unprognostic (4.20e-4)" "unprognostic (7.35e-2)" "unprognostic (7.64e-2)" "unprognostic (2.30e-1)" "unprognostic (6.31e-2)" 1.0 4.3 17.7 0.7 21.0 2.0 0.7 67.8 37.3 0.2 0.1 0.8 1.2 0.6 1.0 0.5 0.6 0.8 0.9 16.5 15.6 0.5 0.7 0.3 1.1 17.8 20.0 0.6 2.5 1.8 18.3 0.2 18.2 0.5 0.6 28.8 0.5 0.5 1.8 2.3 0.6 0.6 10.7 0.9 1.2 4.2 19.2 0.4 0.7 0.8 0.5 0.6 0.2 21.0 0.7 3.2 2.4 7.3 0.2 0.2 1.0 0.3 0.1 1.1 3.0 0.6 0.9 1.9 0.3 1.2 0.7 0.3 1.7 0.6 1.5 8.5 2.0 3.5 3.5 3.1 0.2 2.0 13.7 0.7 0.6 0.4 0.8 0.2 1.4 1.0 1.9 6.6 0.1 0.7 0.5 2.5 1.7 2.4 11.6 0.3 0.8 6.2 0.1 1.3 26.2 12.7 1.2 0.9 1.7 0.2 2.3 2.1 0.5 2.0 2.3 1.6 0.9 1.4 4.2 1.9 0.9 1.4 6.1 6.8 0.9 1.0 0.6 0.8 0.3 1.2 0.6 0.4 0.3 1.2 0.6 0.9 14.2 0.8 0.8 0.8 0.5 1.2 17.7 21.0 67.8 37.3 16.5 15.6 17.8 20.0 18.2 10.7 19.2 21.0 0.5 0.0 0.0 16.3 0.1 0.3 0.4 0.0 0.0 64.5 0.7 0.9 0.5 0.0 0.0 0.0 29.2 0.0 0.1 0.2 0.0 0.2 0.3 0.1 0.1 0.8 0.0 0.0 26.5 0.2 0.1 0.1 0.0 0.2 1.3 0.1 1.1 0.0 0.4 69.0 54.3 0.0 0.0 0.6 0.3 0.2 0.0 0.2 5.4 1.0 0.0 10.3 2.1 15.1 5.7 0.1 0.0 0.4 0.0 0.3 0.0 0.1 0.0 33.0 0.0 1.4 0.3 9.5 17.9 0.0 0.1 0.0 0.1 1.4 0.1 0.1 TMEM159 promethin ENSG00000011638 "Transmembrane protein 159" Q96B96 16 21158377-21180616 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 128.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 121.2;Basal squamous epithelial cells: 176.4;Squamous epithelial cells: 127.5;Suprabasal keratinocytes: 150.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 67.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018033, HPA063509" Approved Approved Vesicles NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" Vesicles "HPA018033: AB_2204762, HPA063509: AB_2685026" "unprognostic (7.62e-3)" "unprognostic (2.42e-1)" "unprognostic (1.99e-2)" "unprognostic (1.06e-1)" "unprognostic (8.68e-2)" "unprognostic (6.80e-2)" "unprognostic (3.32e-1)" "unprognostic (2.93e-1)" "unprognostic (3.35e-1)" "unprognostic (2.93e-3)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.03e-1)" "prognostic favorable (8.11e-5)" "unprognostic (8.28e-2)" "unprognostic (1.28e-1)" "unprognostic (1.84e-2)" "unprognostic (1.57e-2)" 40.2 33.0 3.8 5.4 8.0 3.2 27.0 6.0 4.0 47.4 2.3 42.6 4.3 28.6 7.9 61.9 26.3 20.1 91.6 3.4 3.3 16.5 2.5 19.9 11.7 2.7 3.3 40.8 12.4 14.1 3.2 4.0 3.9 22.1 12.0 5.7 36.8 10.4 128.5 96.0 17.9 17.8 2.4 7.1 21.1 10.5 5.4 5.0 15.4 100.6 16.7 47.9 57.3 2.8 14.3 7.1 7.6 28.7 67.9 44.1 3.4 7.4 27.6 2.9 4.9 5.6 21.4 20.2 7.9 21.6 12.9 23.1 11.7 13.0 3.4 7.7 4.5 9.1 1.9 11.1 15.4 7.2 24.2 17.3 58.8 15.4 48.1 12.2 15.0 10.8 6.9 6.1 5.8 25.2 5.6 6.7 7.0 14.1 3.5 28.9 4.2 7.3 38.1 41.1 1.2 1.1 18.2 25.8 9.8 13.5 46.0 6.5 10.6 5.4 5.4 25.6 1.9 0.5 1.7 7.2 22.2 6.4 5.3 19.5 8.8 7.0 9.7 6.9 9.8 12.2 12.7 8.2 5.4 9.6 9.9 9.6 3.9 7.3 10.3 14.3 14.8 6.6 3.8 8.0 6.0 4.0 3.4 3.3 2.7 3.3 3.9 2.4 5.4 2.8 17.3 9.6 20.9 0.0 12.9 121.2 38.5 31.9 176.4 1.0 53.3 55.2 59.4 15.7 31.8 22.0 0.0 4.8 9.1 34.5 7.9 19.7 0.8 11.4 12.8 13.7 14.5 11.8 1.9 21.3 2.1 44.3 19.4 19.3 15.8 14.0 17.5 0.2 10.2 1.7 0.8 30.6 12.2 15.7 39.0 2.2 67.4 13.8 30.2 4.7 22.7 44.7 7.2 1.0 0.1 24.7 41.8 37.2 3.8 45.3 23.1 21.1 11.2 1.5 32.9 26.5 35.7 2.0 9.9 127.5 150.2 1.9 14.8 5.1 29.9 66.6 TMEM164 "FLJ22679, RP13-360B22.2" ENSG00000157600 "Transmembrane protein 164" Q5U3C3 X 110002631-110182734 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 84.5;Distal enterocytes: 53.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 59.7" "Lineage enriched" "Detected in many" 18 "granulocytes: 59.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038784 Approved Approved "Vesicles,Cell Junctions" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "Cell Junctions" "HPA038784: AB_10670790" "unprognostic (2.14e-3)" "unprognostic (3.35e-1)" "unprognostic (1.50e-1)" "unprognostic (3.65e-3)" "unprognostic (7.94e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (8.17e-6)" "unprognostic (9.85e-3)" "unprognostic (5.68e-2)" "unprognostic (2.29e-2)" "unprognostic (1.30e-2)" "unprognostic (3.95e-1)" "unprognostic (7.66e-2)" "prognostic favorable (3.14e-4)" "unprognostic (1.76e-1)" "unprognostic (1.81e-2)" "unprognostic (4.19e-3)" 16.9 10.3 11.4 9.6 11.8 19.0 12.3 6.8 9.7 5.5 14.3 18.8 21.5 5.3 6.0 13.8 8.1 5.1 22.7 9.0 12.1 11.1 2.0 17.9 6.7 13.5 13.0 13.8 25.4 8.3 9.6 5.2 11.2 8.9 21.2 3.6 9.8 14.4 27.5 20.3 19.2 6.9 8.2 8.4 14.0 1.9 12.3 12.6 13.8 19.3 8.0 5.8 6.8 8.6 10.8 24.3 19.5 12.8 23.7 17.3 11.9 5.3 12.4 11.0 7.1 19.1 16.6 8.6 35.2 8.3 27.1 15.6 17.1 27.9 10.8 23.9 11.7 58.5 13.0 8.1 13.9 26.1 80.1 24.0 48.4 19.9 27.2 30.2 21.8 15.2 18.4 10.2 19.7 21.6 27.4 33.1 17.5 36.9 17.3 12.4 15.1 7.2 17.5 11.3 18.2 20.3 34.0 33.1 15.9 18.1 9.6 25.7 49.0 9.3 6.8 11.0 7.7 5.9 7.9 6.9 24.3 32.0 25.3 59.7 3.3 14.2 0.6 2.9 1.6 0.2 0.7 0.6 2.7 0.6 0.4 0.5 16.3 2.3 1.8 0.5 1.0 1.8 11.4 11.8 6.8 9.7 9.0 12.1 13.5 13.0 11.2 8.2 12.3 8.6 2.9 3.2 36.1 84.5 3.7 4.8 3.7 4.7 4.6 1.2 11.7 9.1 21.3 11.5 6.9 16.5 2.1 2.7 3.5 53.0 3.9 4.6 0.5 6.7 3.8 6.0 27.6 14.5 22.9 11.4 6.3 3.1 7.7 10.7 3.8 4.3 6.4 1.7 13.6 0.0 31.4 12.7 10.2 25.1 9.4 1.3 1.8 12.5 1.8 24.4 28.1 1.0 4.1 34.2 7.6 13.5 15.0 1.5 1.6 9.0 31.9 3.3 5.4 1.3 0.0 6.4 4.1 0.2 0.3 10.4 8.0 2.7 5.2 3.8 21.2 12.3 TMEM167A "FLJ30508, MGC23909, TMEM167" ENSG00000174695 "Transmembrane protein 167A" Q8TBQ9 5 83052846-83077863 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077278 Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 12: NES - Nervous system development" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA077278: " "unprognostic (5.38e-3)" "unprognostic (2.84e-3)" "unprognostic (3.78e-2)" "unprognostic (4.40e-2)" "unprognostic (1.66e-1)" "unprognostic (3.34e-1)" "unprognostic (4.06e-3)" "unprognostic (7.74e-2)" "unprognostic (9.94e-3)" "unprognostic (3.99e-3)" "unprognostic (2.72e-1)" "unprognostic (4.09e-2)" "unprognostic (2.24e-1)" "unprognostic (1.56e-1)" "unprognostic (1.51e-1)" "unprognostic (1.13e-3)" "unprognostic (1.29e-2)" 31.5 48.6 31.8 29.5 32.5 30.8 30.0 35.2 33.7 30.0 29.7 25.3 27.8 21.5 25.8 19.0 15.0 27.6 27.2 32.2 40.3 34.2 33.2 26.5 22.9 33.7 35.4 16.0 23.0 32.0 22.8 35.1 35.1 22.8 29.5 35.3 26.3 19.5 17.4 21.6 24.5 22.7 32.8 22.0 24.1 12.3 36.5 26.5 29.0 21.2 24.0 25.3 15.7 34.2 35.4 21.1 77.7 70.4 111.9 77.6 71.2 54.5 42.6 34.5 44.9 31.8 45.1 22.3 33.4 64.6 45.9 29.1 52.0 70.5 57.1 31.4 32.1 61.2 39.5 49.7 43.5 31.4 38.8 61.0 48.5 44.3 41.4 56.4 43.1 32.7 34.1 44.7 50.9 30.8 38.9 34.4 80.9 18.5 35.4 34.2 50.2 62.5 48.5 27.8 36.8 48.0 36.7 38.2 56.1 70.6 69.2 73.5 59.7 21.8 21.3 63.5 49.2 25.7 77.5 22.3 40.6 56.1 53.0 26.0 21.6 10.3 3.4 20.4 4.0 3.9 4.7 4.3 12.0 3.2 5.0 4.0 12.3 6.0 24.2 5.7 6.2 10.7 31.8 32.5 35.2 33.7 32.2 40.3 33.7 35.4 35.1 32.8 36.5 34.2 56.5 35.3 26.2 21.2 62.8 47.9 60.4 160.3 39.9 47.8 76.2 58.4 53.3 55.8 104.8 49.7 41.7 102.9 63.1 100.0 170.2 86.6 16.7 49.0 135.7 57.2 50.8 56.4 22.7 121.4 306.2 90.6 47.9 71.1 32.4 41.2 50.3 121.6 158.7 33.7 30.2 101.6 103.7 181.4 117.6 20.8 47.2 154.7 94.3 15.0 188.0 68.8 66.9 61.3 50.6 130.7 81.8 49.7 129.3 126.4 84.4 223.3 72.9 31.6 32.9 41.8 79.2 64.1 57.6 79.8 67.2 179.4 64.8 57.1 73.6 125.2 TMEM178A "MGC33926, TMEM178" ENSG00000152154 "Transmembrane protein 178A" Q8NBL3 2 39664982-39717963 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 135.5" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 32.4;Excitatory neurons: 109.1;Inhibitory neurons: 109.2;Oligodendrocyte precursor cells: 33.7" "Group enriched" "Detected in many" 4 "endometrial cancer: 10.2;glioma: 13.2;prostate cancer: 19.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AF22: 138.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052128 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 45: Intestine - Brush border" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles Nucleoplasm "HPA052128: AB_2681738" "unprognostic (3.35e-2)" "unprognostic (3.18e-1)" "unprognostic (5.94e-2)" "unprognostic (2.86e-1)" "unprognostic (1.04e-1)" "unprognostic (5.85e-2)" "unprognostic (3.24e-3)" "unprognostic (1.82e-3)" "unprognostic (2.22e-1)" "unprognostic (9.74e-2)" "unprognostic (5.11e-4)" "unprognostic (1.13e-1)" "unprognostic (6.01e-3)" "unprognostic (2.80e-3)" "unprognostic (3.46e-2)" "unprognostic (2.83e-2)" "unprognostic (3.01e-3)" 5.9 7.6 65.4 0.6 71.3 0.2 6.2 135.5 104.1 4.1 38.6 8.9 1.9 3.6 1.5 1.8 6.3 2.7 4.5 71.7 51.3 42.7 9.9 6.7 0.5 64.7 54.9 5.9 4.6 2.3 12.9 3.2 65.5 11.6 1.7 15.7 21.9 1.6 2.8 3.3 3.2 2.4 65.7 2.6 8.6 2.2 51.5 0.5 12.3 1.9 0.5 3.9 3.0 108.0 0.0 0.0 138.7 0.1 0.1 3.3 0.2 0.6 0.1 0.0 0.3 0.0 0.3 0.0 3.7 0.0 0.0 0.3 4.5 0.0 0.5 0.3 0.1 0.0 0.0 0.4 1.1 0.1 0.0 2.6 0.3 0.0 0.4 4.3 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.2 17.7 0.2 0.1 1.7 0.0 0.0 1.0 0.2 25.7 0.6 0.0 0.6 0.3 23.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 65.4 71.3 135.5 104.1 71.7 51.3 64.7 54.9 65.5 65.7 51.5 108.0 3.2 0.0 2.0 14.7 0.0 0.4 0.5 0.6 1.8 9.1 1.1 32.4 3.9 0.0 1.3 12.9 6.2 0.3 0.1 0.8 0.0 0.2 0.4 3.0 1.2 4.3 16.1 0.0 109.1 0.2 0.0 2.6 0.0 6.5 0.0 1.4 0.7 0.5 0.2 1.7 109.2 0.4 2.0 0.0 0.4 0.1 0.0 0.2 1.8 7.5 0.0 1.1 0.0 33.7 19.3 0.4 0.3 0.0 0.0 3.7 0.5 0.7 4.3 6.1 0.0 0.9 0.6 0.2 0.5 0.1 0.6 0.5 0.1 0.5 0.4 0.3 TMEM178B DKFZp547G036 ENSG00000261115 "Transmembrane protein 178B" H3BS89 7 141074064-141480380 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 11.3;parathyroid gland: 11.9;tongue: 12.2" "Group enriched" "Detected in many" 5 "Astrocytes: 175.0;Excitatory neurons: 584.8;Inhibitory neurons: 566.2;Oligodendrocyte precursor cells: 306.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 6.0;HDLM-2: 5.7;NTERA-2: 5.1;RPTEC TERT1: 8.2;SCLC-21H: 6.4;WM-115: 8.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048771 Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles Nucleoli "HPA048771: AB_2680517" "unprognostic (7.33e-3)" "unprognostic (2.02e-2)" "unprognostic (2.83e-2)" "unprognostic (7.79e-4)" "unprognostic (1.94e-1)" "unprognostic (1.49e-1)" "unprognostic (2.95e-1)" "unprognostic (1.69e-2)" "unprognostic (6.94e-2)" "unprognostic (2.21e-2)" "unprognostic (7.17e-4)" "unprognostic (1.05e-1)" "prognostic favorable (4.10e-4)" "unprognostic (2.02e-1)" "unprognostic (1.10e-1)" "unprognostic (5.35e-3)" "unprognostic (8.98e-2)" 0.3 1.4 3.7 0.6 5.4 0.0 0.5 0.2 7.4 0.3 0.0 0.8 0.0 0.8 0.4 0.7 0.3 0.3 11.3 7.0 5.0 1.3 0.0 0.3 1.4 1.5 5.9 0.1 0.9 11.9 4.2 0.0 5.6 2.3 0.3 5.5 1.2 0.5 4.6 0.2 0.4 1.0 0.6 0.7 0.3 0.5 5.2 1.4 8.5 12.2 3.1 0.5 0.2 1.9 0.0 0.1 0.0 0.0 0.5 0.2 1.5 0.1 2.3 0.7 0.8 0.0 0.0 1.9 2.0 0.1 0.5 0.0 6.0 0.0 1.9 5.7 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 5.1 0.0 0.0 0.4 0.9 2.6 8.2 2.4 6.4 3.9 0.1 0.2 0.9 1.2 0.8 0.0 0.0 0.1 0.9 2.7 0.0 0.0 0.0 0.0 0.4 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 5.4 0.2 7.4 7.0 5.0 1.5 5.9 5.6 0.6 5.2 1.9 1.3 0.0 0.0 175.0 0.0 0.5 0.7 0.9 0.6 25.5 1.4 0.5 48.7 0.0 1.3 1.8 2.1 0.0 0.0 0.0 1.9 0.1 1.3 0.2 0.1 1.2 0.0 0.0 584.8 0.4 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.1 30.3 566.2 0.0 2.0 0.0 0.0 1.6 0.0 0.1 1.8 24.4 0.0 4.2 0.0 306.1 81.3 0.8 0.0 0.7 0.0 2.2 0.0 3.4 0.2 1.8 0.0 3.9 0.8 1.4 0.7 2.9 0.1 0.3 0.3 0.2 0.1 2.0 TMEM181 "GPR178, KIAA1423" ENSG00000146433 "Transmembrane protein 181" Q9P2C4 6 158536436-158635428 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040189 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 24: Non-specific - Transcription regulation" Vesicles "Golgi apparatus" "HPA040189: AB_10793959" "unprognostic (1.93e-2)" "prognostic unfavorable (7.26e-4)" "unprognostic (9.87e-2)" "unprognostic (6.51e-2)" "unprognostic (3.09e-1)" "unprognostic (1.49e-2)" "unprognostic (1.09e-2)" "unprognostic (1.16e-1)" "unprognostic (2.07e-1)" "prognostic unfavorable (1.09e-4)" "unprognostic (1.14e-1)" "unprognostic (2.34e-1)" "unprognostic (4.07e-2)" "unprognostic (1.46e-1)" "unprognostic (1.93e-1)" "unprognostic (4.36e-1)" "unprognostic (3.26e-1)" 14.6 12.4 16.6 12.2 17.0 9.1 18.7 9.7 17.5 27.3 8.3 22.7 24.6 15.2 9.0 13.1 12.7 16.5 10.3 17.6 17.5 7.9 14.9 13.3 9.4 13.3 15.1 10.3 34.3 13.4 11.8 15.0 14.1 20.0 24.8 10.5 52.3 20.9 10.2 16.1 28.5 17.4 12.9 14.3 35.7 21.3 22.3 6.3 21.3 8.7 8.2 20.6 13.4 14.9 22.1 12.6 17.5 27.0 45.1 41.1 33.4 49.1 28.6 25.1 28.4 21.5 26.5 9.3 24.7 41.0 53.5 32.0 26.1 32.4 39.6 13.7 18.7 17.3 18.9 45.6 36.8 21.9 15.8 34.3 31.2 27.9 37.6 37.6 40.7 13.1 33.4 11.3 41.4 13.3 9.7 27.1 13.6 43.8 15.9 9.3 20.1 10.6 23.9 17.1 51.3 35.3 36.0 33.3 24.2 23.9 12.7 30.4 39.1 25.7 17.4 43.1 43.0 6.6 4.9 10.0 31.0 26.8 25.1 5.7 1.1 3.0 2.2 1.1 1.7 0.4 1.2 1.8 0.8 0.4 1.1 1.5 0.7 2.0 1.9 1.0 1.3 0.8 16.6 17.0 9.7 17.5 17.6 17.5 13.3 15.1 14.1 12.9 22.3 14.9 26.7 12.8 33.1 19.9 9.4 20.4 15.6 20.5 17.6 15.6 30.0 18.8 14.2 27.1 23.1 16.5 18.8 8.8 46.0 47.2 3.9 23.3 4.2 16.8 27.7 27.5 44.3 21.5 61.1 32.7 12.5 16.6 49.5 40.5 11.4 36.8 21.0 22.5 10.2 20.2 66.3 35.9 18.3 15.3 16.4 6.7 13.1 14.7 14.2 28.1 13.3 6.0 51.5 43.2 61.7 35.3 25.7 17.7 26.6 37.5 39.4 4.6 25.8 14.6 6.6 12.7 17.8 13.1 22.7 23.6 21.0 5.2 27.0 24.2 30.5 37.1 TMEM182 FLJ30294 ENSG00000170417 "Transmembrane protein 182" Q6ZP80 2 102736905-103019900 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 24 "heart muscle: 97.6;skeletal muscle: 150.7;tongue: 127.7" "Cell type enriched" "Detected in many" 6 "Cardiomyocytes: 150.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA045861 Approved Nucleoplasm,Vesicles NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Vesicles" "HPA045861: AB_2679475" "unprognostic (1.39e-1)" "unprognostic (3.42e-2)" "unprognostic (5.10e-2)" "unprognostic (1.12e-4)" "unprognostic (5.35e-2)" "unprognostic (7.01e-2)" "unprognostic (1.13e-2)" "unprognostic (1.10e-1)" "unprognostic (7.03e-3)" "unprognostic (2.34e-1)" "unprognostic (4.19e-2)" "unprognostic (3.42e-2)" "unprognostic (9.88e-2)" "unprognostic (4.61e-2)" "unprognostic (1.10e-1)" "unprognostic (3.53e-1)" "unprognostic (2.36e-2)" 2.7 1.6 2.2 0.7 2.0 0.6 2.3 2.6 2.9 2.9 2.2 1.8 1.9 1.1 5.3 3.9 2.1 1.8 97.6 2.5 3.1 2.1 2.0 1.3 1.8 2.8 2.7 1.5 2.1 3.6 2.6 1.4 3.0 4.0 2.3 1.5 2.0 2.1 150.7 0.5 1.2 1.1 2.5 1.6 2.2 1.4 2.6 1.8 3.0 127.7 1.4 2.2 0.6 2.7 4.9 3.3 2.4 7.3 2.8 2.4 6.9 2.5 2.2 2.4 4.4 10.7 7.3 4.5 9.0 1.4 6.1 3.3 2.6 3.7 5.4 11.6 3.5 6.6 1.4 6.7 3.0 6.2 4.4 3.2 7.6 4.5 5.2 1.9 0.4 6.4 5.2 1.2 3.5 4.6 3.9 5.7 4.2 5.9 3.6 3.4 6.3 3.7 5.7 6.2 5.2 1.9 4.1 3.3 10.3 3.5 3.0 3.2 0.7 4.2 3.5 2.7 3.1 3.9 13.0 5.5 3.8 8.4 6.3 0.0 0.0 0.2 2.5 0.2 2.8 3.6 1.5 1.3 0.9 1.2 2.4 2.4 0.0 2.4 0.3 2.9 0.5 1.1 2.2 2.0 2.6 2.9 2.5 3.1 2.8 2.7 3.0 2.5 2.6 2.7 0.6 22.4 12.3 1.3 3.6 0.4 1.0 1.8 1.2 0.3 8.1 2.4 150.6 0.0 15.3 3.7 0.0 2.3 4.2 0.5 0.0 1.8 0.6 2.4 1.1 2.0 6.6 3.6 6.1 3.3 2.6 6.9 4.1 1.6 3.8 1.2 0.7 2.3 1.2 0.0 10.8 2.6 2.0 0.8 0.7 0.6 0.6 1.3 7.2 6.5 0.1 2.4 1.0 8.5 3.4 2.4 1.1 0.7 2.7 1.0 1.0 2.4 12.8 0.3 0.0 4.6 2.3 1.0 2.4 2.5 0.6 1.1 2.9 1.1 1.8 2.8 TMEM184C "FLJ10846, TMEM34" ENSG00000164168 "Transmembrane protein 184C" Q9NVA4 4 147617386-147672044 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 131.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054013 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 16: U-266 - Nucleosome" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles Nucleoplasm "HPA054013: AB_2682343" "unprognostic (5.45e-3)" "unprognostic (2.49e-2)" "unprognostic (3.93e-3)" "unprognostic (3.58e-2)" "unprognostic (2.02e-1)" "unprognostic (8.14e-2)" "unprognostic (1.32e-2)" "unprognostic (7.72e-3)" "unprognostic (1.48e-1)" "unprognostic (1.99e-1)" "prognostic unfavorable (6.37e-4)" "unprognostic (1.13e-1)" "prognostic favorable (2.31e-7)" "unprognostic (4.68e-2)" "unprognostic (3.03e-1)" "unprognostic (2.20e-1)" "unprognostic (4.31e-3)" 14.0 20.7 7.8 12.4 10.0 7.9 12.8 10.0 15.9 16.1 10.3 14.8 17.2 14.2 11.2 12.9 13.6 13.4 14.3 10.6 8.9 20.3 20.4 12.7 11.4 8.1 8.7 16.5 15.4 131.7 7.1 19.6 8.7 16.7 16.4 16.2 17.3 16.7 14.7 11.8 16.9 14.3 9.2 11.2 15.3 12.0 9.9 12.6 32.6 16.4 13.8 14.5 7.6 11.2 17.4 27.3 33.7 25.6 45.0 44.6 22.3 32.6 37.5 23.7 26.9 22.7 32.7 16.3 15.7 25.1 23.2 20.5 28.4 24.6 25.8 36.4 16.2 21.1 19.8 16.2 36.3 28.8 29.8 33.2 33.0 26.3 26.9 34.9 30.7 18.4 27.2 44.1 33.6 27.0 24.8 10.2 21.7 40.4 15.7 24.3 11.6 28.2 26.3 32.6 25.8 33.4 18.3 27.0 28.5 25.8 26.8 17.5 31.5 29.2 15.7 24.3 21.0 47.9 68.0 21.5 34.9 17.0 32.7 20.5 12.9 14.7 15.3 16.5 19.4 10.4 13.9 13.9 15.8 12.1 13.0 12.4 10.0 14.6 17.9 10.8 14.3 11.0 7.8 10.0 10.0 15.9 10.6 8.9 8.1 8.7 8.7 9.2 9.9 11.2 8.3 9.6 9.3 7.8 9.5 4.6 8.0 6.3 6.8 8.6 8.3 5.7 19.8 8.6 11.5 5.5 12.5 14.3 12.5 9.8 1.9 12.8 34.6 8.0 11.1 10.0 5.4 8.2 10.4 12.7 12.0 10.6 7.7 9.9 21.5 7.3 8.2 11.8 10.4 11.8 12.7 7.7 6.1 11.9 5.1 13.7 10.8 9.1 5.4 6.5 6.4 8.5 7.2 8.5 14.1 8.6 6.7 14.7 9.0 7.8 9.7 5.8 5.2 6.5 6.6 9.5 8.8 6.5 5.4 10.6 3.4 8.6 12.0 10.6 11.3 7.0 TMEM198 "MGC99813, TMEM198A" ENSG00000188760 "Transmembrane protein 198" Q66K66 2 219543663-219550595 "Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.0" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 19.2;Horizontal cells: 21.9;Muller glia cells: 10.9;Proximal enterocytes: 12.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 20.0;SH-SY5Y: 17.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042385, HPA062897" Enhanced Approved Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Vesicles "HPA042385: AB_2677972, HPA062897: " "unprognostic (2.59e-2)" "unprognostic (8.51e-2)" "unprognostic (5.97e-3)" "unprognostic (2.77e-1)" "unprognostic (4.43e-2)" "unprognostic (8.09e-2)" "unprognostic (1.83e-1)" "unprognostic (1.03e-1)" "unprognostic (4.28e-1)" "unprognostic (2.06e-1)" "prognostic favorable (6.89e-4)" "unprognostic (6.39e-2)" "unprognostic (7.91e-3)" "unprognostic (3.41e-3)" "unprognostic (2.11e-1)" "unprognostic (1.72e-1)" "unprognostic (1.58e-1)" 3.2 8.2 10.8 1.4 9.7 0.1 3.0 12.1 19.4 4.6 2.3 2.7 8.9 5.2 1.0 2.0 3.6 1.8 4.4 21.0 8.4 4.0 4.3 3.2 0.7 7.7 7.4 14.7 12.0 3.1 18.3 1.1 6.0 4.2 0.6 2.5 3.8 1.8 2.8 1.5 4.4 1.6 7.4 2.2 4.6 5.9 8.5 0.5 4.0 2.0 0.7 3.8 2.0 8.8 0.6 0.1 5.6 9.6 1.1 1.0 4.9 2.8 1.5 2.3 2.0 12.5 1.6 2.6 2.7 1.8 5.8 3.5 2.0 1.4 0.4 8.7 2.4 2.0 2.9 10.4 1.6 0.7 4.7 2.4 0.8 1.1 2.7 2.5 0.0 1.8 7.8 8.1 1.4 1.2 0.1 0.6 7.3 1.0 0.9 0.2 3.4 2.9 1.4 1.4 20.0 17.4 0.7 2.0 5.0 1.0 0.2 4.0 0.1 2.5 1.0 2.3 1.2 7.7 2.4 2.7 2.3 0.2 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 10.8 9.7 12.1 19.4 21.0 8.4 7.7 7.4 6.0 7.4 8.5 8.8 0.3 0.0 1.1 2.0 0.8 0.1 1.4 1.4 1.2 9.3 3.5 4.3 1.8 4.3 0.6 0.0 2.1 1.0 0.4 0.4 1.9 3.9 0.8 0.3 2.6 0.4 19.2 0.0 4.9 7.9 0.9 3.9 1.5 0.6 0.0 1.6 0.0 1.6 0.3 21.9 4.8 2.4 2.0 0.3 0.9 1.4 2.8 0.0 1.8 0.0 0.6 10.9 0.0 3.0 1.2 1.5 4.0 4.9 1.1 0.8 12.4 1.8 0.6 7.4 0.0 1.6 2.8 8.4 4.2 0.4 0.1 2.9 0.4 5.5 0.5 0.4 TMEM209 "FLJ14803, NET31" ENSG00000146842 "Transmembrane protein 209" Q96SK2 7 130164713-130207770 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031678 Uncertain Approved "Nuclear membrane,Nuclear speckles,Vesicles" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nuclear membrane, Nuclear speckles, Vesicles" "HPA031678: AB_10603135" "unprognostic (3.03e-1)" "unprognostic (5.06e-2)" "unprognostic (1.55e-1)" "unprognostic (9.54e-2)" "unprognostic (1.85e-1)" "unprognostic (1.36e-1)" "unprognostic (4.50e-3)" "unprognostic (5.98e-2)" "unprognostic (1.25e-1)" "unprognostic (1.66e-1)" "unprognostic (3.19e-1)" "unprognostic (6.00e-2)" "unprognostic (2.34e-3)" "unprognostic (1.11e-1)" "unprognostic (3.48e-1)" "unprognostic (1.68e-2)" "unprognostic (3.24e-1)" 8.9 15.3 4.1 8.4 6.2 9.6 10.6 7.2 6.5 7.4 13.0 11.0 8.8 10.8 9.5 5.5 9.6 6.4 6.2 4.0 5.2 8.6 10.4 9.2 11.9 6.1 6.1 10.2 8.5 15.1 4.4 9.5 6.4 8.3 11.2 13.3 7.9 8.4 5.2 7.2 10.7 9.0 5.9 10.5 7.6 15.0 5.4 14.2 16.2 7.7 12.1 7.6 4.3 9.6 23.4 21.8 29.3 36.7 16.8 17.2 21.4 20.8 20.9 18.3 24.7 23.0 39.2 34.6 15.1 13.3 34.5 34.2 34.7 24.2 33.0 42.7 20.0 17.9 34.0 16.5 29.6 38.2 17.2 18.9 24.6 37.0 36.8 11.4 14.5 35.1 58.9 38.2 23.2 30.2 73.2 23.6 44.1 20.9 19.4 38.9 33.1 57.4 19.1 29.3 26.2 40.0 47.5 75.8 31.3 22.7 23.7 25.6 11.4 33.0 13.1 35.4 50.6 51.7 81.6 70.4 54.7 43.4 53.0 16.1 12.2 13.8 22.0 18.3 23.0 18.3 22.3 20.2 12.0 17.3 25.6 22.3 1.8 19.5 16.8 14.9 24.6 15.1 4.1 6.2 7.2 6.5 4.0 5.2 6.1 6.1 6.4 5.9 5.4 9.6 12.3 3.2 12.3 11.4 15.3 4.7 4.0 8.2 6.8 13.6 8.8 5.2 8.6 10.0 9.8 9.2 4.2 8.9 15.2 7.2 1.9 6.4 33.5 9.6 8.0 9.5 13.8 25.9 10.4 9.1 9.3 7.5 7.7 10.4 10.1 10.0 9.7 9.4 7.9 5.0 13.0 11.9 8.2 13.1 4.4 8.5 6.5 7.8 7.2 15.0 7.7 18.1 8.2 10.6 20.9 7.6 11.6 5.3 11.0 5.3 13.4 4.9 9.8 14.6 0.0 9.0 5.9 16.6 16.0 6.4 5.4 6.6 13.1 12.1 9.5 3.7 TMEM215 ENSG00000188133 "Transmembrane protein 215" Q68D42 9 32783540-32789201 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 6.9;retina: 18.3;testis: 3.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 572.0;Early spermatids: 129.9;Late spermatids: 302.1" "Cancer enriched" "Detected in single" 14 "thyroid cancer: 4.9" "Region enriched" "Detected in many" 4 "thalamus: 6.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA052804, HPA063207" Supported "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: NTERA-2 - Transcription" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "Endoplasmic reticulum, Vesicles" "HPA052804: AB_2681957, HPA063207: AB_2732697" "unprognostic (1.31e-2)" "unprognostic (4.57e-2)" "unprognostic (1.07e-1)" "unprognostic (2.92e-2)" "unprognostic (5.85e-2)" "unprognostic (4.38e-3)" "unprognostic (2.17e-3)" "unprognostic (2.82e-1)" "unprognostic (2.72e-1)" "unprognostic (2.64e-1)" "unprognostic (3.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.54e-1)" "unprognostic (2.32e-2)" 0.0 0.0 1.2 0.0 0.9 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.7 1.5 0.0 0.0 0.0 0.0 0.2 1.6 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 18.3 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 3.9 6.9 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.0 0.5 0.7 1.5 0.2 1.6 0.3 0.3 6.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 572.0 0.0 0.0 0.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 129.9 0.0 1.2 0.4 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 3.7 0.0 0.0 0.1 1.7 0.3 0.0 0.0 0.0 0.0 302.1 2.8 0.1 0.0 0.0 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 25.9 0.0 0.0 0.1 3.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMEM231 "ALYE870, FLJ22167, JBTS20, MKS11, PRO1886" ENSG00000205084 "Transmembrane protein 231" Q9H6L2 16 75536741-75556268 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "fallopian tube: 48.5" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 52.1;Endometrial ciliated cells: 121.2;Respiratory ciliated cells: 132.2;Rod photoreceptor cells: 33.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042081 Enhanced Approved Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA042081: AB_10795391" "unprognostic (4.29e-2)" "unprognostic (9.84e-2)" "unprognostic (8.07e-2)" "unprognostic (2.71e-3)" "unprognostic (1.03e-1)" "unprognostic (9.34e-2)" "unprognostic (2.90e-2)" "unprognostic (2.81e-1)" "unprognostic (2.92e-1)" "unprognostic (1.69e-2)" "unprognostic (3.34e-3)" "unprognostic (7.84e-2)" "unprognostic (3.73e-2)" "unprognostic (1.22e-1)" "unprognostic (1.66e-1)" "unprognostic (1.12e-1)" "unprognostic (1.28e-1)" 2.4 3.3 5.1 1.4 5.1 1.4 2.5 5.0 5.2 3.6 11.9 2.5 2.4 4.2 3.6 1.7 48.5 3.2 6.0 5.3 6.5 2.9 1.1 4.6 1.6 8.8 10.3 4.7 3.1 7.0 4.9 2.2 7.1 3.5 1.9 5.2 1.5 3.5 1.0 2.3 2.6 5.5 8.5 1.5 1.9 4.5 7.3 0.9 5.8 1.2 1.0 2.6 1.7 5.1 4.0 2.6 7.1 12.0 6.8 16.6 3.8 5.0 6.3 6.1 7.3 1.4 7.0 5.0 6.7 6.9 5.1 10.3 0.8 5.3 3.9 0.9 2.9 0.3 3.6 1.6 5.9 2.9 2.1 3.7 7.0 6.2 15.1 11.0 3.3 4.5 4.8 0.2 1.8 11.5 1.8 5.2 4.0 0.8 2.1 0.9 1.0 11.5 7.4 1.6 5.7 3.8 8.8 2.5 4.4 2.3 2.3 3.0 5.1 4.7 3.7 3.0 2.6 9.1 8.4 1.6 11.9 1.3 4.6 1.8 0.3 0.2 0.6 0.4 1.5 2.2 0.7 1.2 1.0 1.0 0.6 1.0 2.5 0.4 0.2 1.3 0.2 0.6 5.1 5.1 5.0 5.2 5.3 6.5 8.8 10.3 7.1 8.5 7.3 5.1 6.4 3.2 6.3 9.4 3.0 1.0 4.7 5.5 1.8 18.3 5.3 6.1 5.2 1.5 14.0 7.3 52.1 1.1 1.1 3.7 0.0 3.0 17.6 121.2 8.1 6.3 3.0 1.7 11.6 2.3 1.2 5.2 3.6 10.6 1.3 6.1 4.2 1.5 0.9 13.5 11.4 5.0 18.3 1.2 0.8 5.3 1.8 1.5 0.0 1.0 2.8 6.0 0.0 9.5 7.6 1.5 3.8 3.8 2.0 5.0 16.8 2.1 132.2 33.1 0.0 6.6 6.1 15.3 9.8 1.8 1.0 0.3 2.3 6.0 4.2 2.5 TMEM234 "C1orf91, dJ622L5.7, FLJ90779, RP4-622L5" ENSG00000160055 "Transmembrane protein 234" Q8WY98 1 32214472-32222359 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 55.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA015049 Uncertain Approved Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA015049: AB_1856409" "unprognostic (1.39e-2)" "unprognostic (1.36e-1)" "unprognostic (1.52e-1)" "unprognostic (1.26e-1)" "unprognostic (2.44e-3)" "unprognostic (3.09e-1)" "prognostic unfavorable (2.35e-5)" "unprognostic (2.67e-1)" "unprognostic (1.07e-2)" "unprognostic (6.49e-2)" "unprognostic (2.66e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (4.12e-5)" "unprognostic (1.95e-1)" "unprognostic (2.44e-1)" "unprognostic (7.92e-2)" "unprognostic (2.37e-2)" 6.5 7.4 5.7 2.6 5.8 2.8 6.8 5.0 6.4 7.9 7.4 6.4 2.2 7.6 9.4 9.0 7.3 3.4 9.2 5.7 6.1 9.7 6.3 6.4 3.5 5.9 6.7 9.9 5.8 6.9 12.3 5.9 6.0 8.5 4.1 6.1 7.2 7.0 3.0 4.8 5.2 4.4 5.2 7.5 5.6 9.0 5.8 3.1 12.3 1.7 3.5 6.6 7.6 5.4 10.0 7.5 4.2 4.4 12.0 9.4 4.4 14.6 10.5 7.3 5.5 5.4 9.8 3.1 16.1 13.5 5.7 8.0 5.4 10.5 6.2 6.4 5.9 6.1 11.9 6.2 8.7 7.4 4.0 11.9 10.5 7.6 5.5 12.8 10.7 3.3 5.9 1.9 12.4 3.0 2.9 6.2 7.6 2.5 5.7 4.0 3.3 3.6 16.3 5.1 5.3 5.4 10.6 5.7 5.0 13.6 2.8 2.3 12.9 2.6 4.1 10.3 10.6 3.1 1.8 1.3 8.0 2.6 9.8 25.9 11.9 19.1 5.8 13.3 9.3 6.9 4.6 6.6 11.4 6.9 3.3 4.2 35.8 10.8 9.3 8.6 3.1 6.7 5.7 5.8 5.0 6.4 5.7 6.1 5.9 6.7 6.0 5.2 5.8 5.4 7.5 9.6 1.5 10.4 8.3 2.7 6.6 14.5 5.2 5.3 9.0 9.1 3.6 4.3 11.4 23.9 2.1 26.0 5.0 17.4 1.9 20.9 27.8 17.9 9.1 7.5 6.0 7.4 10.8 15.5 23.0 9.1 16.3 10.0 3.8 10.8 6.4 5.6 19.3 1.7 7.8 11.8 10.2 8.3 3.2 55.6 9.3 8.2 14.2 8.4 11.4 8.6 9.2 3.5 2.8 18.4 12.2 7.9 5.1 5.6 12.5 11.0 23.7 13.5 6.6 5.7 9.2 31.8 15.0 5.9 3.1 21.3 6.9 15.2 9.9 8.0 TMEM241 "C18orf45, FLJ44259, MGC11386" ENSG00000134490 "Transmembrane protein 241" Q24JQ0 18 23197144-23437961 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 70.8;Oligodendrocyte precursor cells: 21.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "NK-cell: 6.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029489, HPA059922" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" Vesicles "HPA029489: AB_2673067, HPA059922: AB_2684164" "unprognostic (1.44e-3)" "unprognostic (1.92e-1)" "unprognostic (7.80e-2)" "unprognostic (1.02e-2)" "unprognostic (1.37e-1)" "unprognostic (6.48e-2)" "unprognostic (1.15e-4)" "unprognostic (7.07e-2)" "unprognostic (6.65e-2)" "unprognostic (1.19e-1)" "unprognostic (1.81e-3)" "unprognostic (9.53e-3)" "unprognostic (1.15e-1)" "unprognostic (1.42e-1)" "unprognostic (2.95e-1)" "unprognostic (4.93e-1)" "prognostic unfavorable (5.80e-4)" 2.1 0.6 0.7 1.8 0.9 1.1 2.3 0.0 1.7 1.8 0.7 1.7 1.5 2.0 1.6 1.7 1.7 1.6 1.5 1.5 0.2 1.1 1.7 1.4 1.4 0.1 0.1 1.6 1.3 2.4 1.1 2.3 0.0 0.9 2.2 0.3 1.2 0.9 1.0 0.8 1.1 2.9 0.0 1.5 1.4 0.6 0.2 1.0 2.2 0.9 1.5 1.6 1.0 1.1 3.2 4.5 1.2 4.1 5.5 5.3 3.5 1.6 1.9 1.9 3.8 1.3 7.6 13.1 3.4 2.7 6.6 6.0 2.9 7.8 5.3 1.4 1.5 2.4 4.5 3.7 3.3 2.7 2.1 5.3 6.5 6.3 6.6 4.1 6.6 6.3 5.5 4.1 5.3 4.6 2.6 0.5 1.8 10.6 2.9 1.9 5.8 11.2 2.6 1.9 4.6 4.3 7.1 3.2 4.2 4.3 4.0 0.8 3.0 10.3 2.4 3.6 3.9 8.4 8.1 5.3 5.1 8.4 7.2 1.2 0.5 0.0 0.9 2.2 1.3 1.3 0.2 0.9 2.0 2.2 0.8 1.2 0.0 6.0 0.8 0.7 1.2 1.1 0.7 0.9 0.0 1.7 1.5 0.2 0.1 0.1 0.0 0.0 0.2 1.1 3.7 0.0 6.9 4.9 3.5 2.8 3.3 3.9 4.0 1.0 16.1 7.9 1.4 1.5 5.2 3.7 4.2 8.3 4.7 1.8 0.0 2.3 0.0 2.4 4.6 2.5 1.2 3.8 70.8 2.2 8.7 3.9 7.1 3.2 2.5 4.2 3.3 3.8 3.1 10.1 16.0 4.0 6.1 0.6 2.9 0.3 1.8 2.4 1.8 11.2 1.4 1.0 5.2 21.6 9.9 3.0 3.1 1.2 5.7 4.6 2.0 3.3 8.3 1.3 0.0 4.2 3.0 1.4 5.5 6.2 4.4 4.7 2.1 4.2 2.3 2.9 TMEM248 "C7orf42, FLJ10099, FLJ13090" ENSG00000106609 "Transmembrane protein 248" Q9NWD8 7 66921225-66958551 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016495 Uncertain Approved Vesicles NA NA 1600000 "Cluster 26: Non-specific - Mitochondria" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA016495: AB_1848643" "unprognostic (6.74e-2)" "unprognostic (1.73e-2)" "unprognostic (4.86e-2)" "unprognostic (4.64e-2)" "unprognostic (6.67e-3)" "unprognostic (9.36e-2)" "unprognostic (1.39e-2)" "unprognostic (4.14e-2)" "unprognostic (2.32e-1)" "unprognostic (4.54e-2)" "unprognostic (9.18e-2)" "unprognostic (2.80e-3)" "unprognostic (1.30e-1)" "unprognostic (8.96e-2)" "unprognostic (5.11e-2)" "unprognostic (8.28e-2)" "unprognostic (5.57e-2)" 31.8 39.7 29.2 27.5 30.8 17.8 34.8 25.3 29.0 46.6 57.5 40.8 42.4 44.3 40.6 26.6 45.0 38.6 32.4 32.2 36.1 36.3 49.4 38.7 36.5 27.3 31.0 50.0 40.3 50.0 31.7 34.5 31.0 43.1 41.1 39.0 39.6 40.9 23.1 29.5 37.4 39.2 26.3 34.2 43.6 32.6 40.1 29.5 46.1 21.4 35.0 34.0 32.4 28.0 46.4 53.3 44.2 63.4 98.2 75.0 38.7 55.7 95.1 51.8 55.9 38.9 59.2 46.7 66.3 75.5 70.8 40.8 38.3 45.9 64.0 43.1 28.2 34.2 36.9 45.4 63.5 57.6 45.5 68.0 52.4 43.6 36.1 75.4 68.5 36.1 66.6 30.6 83.4 28.1 54.3 70.5 65.9 47.5 36.1 39.3 51.4 79.3 70.3 35.1 30.7 65.6 49.1 89.0 50.6 65.6 44.8 52.1 63.9 72.4 35.4 48.0 61.9 37.2 45.4 52.1 60.6 62.9 70.5 2.3 4.0 7.7 6.0 4.3 7.2 8.3 6.5 6.4 3.2 8.1 6.3 6.8 5.8 7.3 2.7 8.3 4.7 1.9 29.2 30.8 25.3 29.0 32.2 36.1 27.3 31.0 31.0 26.3 40.1 28.0 55.1 51.3 42.7 14.7 66.2 64.5 53.5 23.6 46.7 18.5 60.6 44.2 25.0 51.5 25.2 53.3 6.2 48.3 75.2 100.8 11.7 37.0 106.2 37.8 34.5 51.7 27.6 45.9 25.8 47.2 81.2 60.9 55.5 35.0 28.5 44.8 58.2 109.9 52.7 18.5 26.4 82.6 16.2 65.7 76.5 172.3 63.6 53.0 49.8 20.6 46.2 96.7 62.8 24.1 27.7 60.2 62.3 65.8 76.5 108.8 64.4 34.3 36.9 12.7 32.9 40.3 47.7 111.5 57.9 42.2 73.9 88.1 64.4 46.4 60.3 98.7 TMEM25 FLJ14399 ENSG00000149582 "Transmembrane protein 25" Q86YD3 11 118531041-118547280 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 149.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 35.9;SK-BR-3: 33.7;T-47d: 43.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA012163, HPA051562" Approved Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" NA NA 6900000 "Cluster 48: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Golgi apparatus, Vesicles" "HPA012163: AB_1858112, HPA051562: AB_2681535" "unprognostic (1.53e-2)" "unprognostic (7.18e-2)" "unprognostic (2.43e-1)" "unprognostic (6.69e-2)" "unprognostic (3.61e-1)" "unprognostic (6.50e-2)" "unprognostic (1.71e-1)" "unprognostic (4.45e-3)" "unprognostic (1.58e-1)" "unprognostic (3.42e-1)" "unprognostic (1.66e-2)" "unprognostic (8.19e-2)" "prognostic favorable (0.00e+0)" "unprognostic (1.15e-1)" "unprognostic (2.51e-1)" "unprognostic (1.26e-1)" "unprognostic (7.01e-2)" 6.9 25.3 35.0 3.8 36.0 2.2 14.6 33.9 44.3 14.9 32.2 16.0 46.0 15.3 25.7 11.1 13.7 8.9 8.9 37.5 36.7 18.6 23.1 9.9 4.8 32.1 30.3 23.4 17.6 23.3 29.5 6.0 32.0 15.7 3.7 22.3 21.0 18.3 18.5 8.7 35.2 10.8 31.5 5.3 13.3 6.5 35.1 5.1 15.9 9.9 5.3 14.4 11.6 35.1 3.4 0.7 5.8 9.5 6.0 0.9 5.6 5.2 9.9 4.9 9.8 27.1 18.8 0.3 20.1 5.3 10.9 14.8 0.0 18.3 4.4 11.9 11.1 0.5 5.4 6.0 16.0 0.3 0.5 7.3 10.9 5.3 0.9 35.9 7.2 13.7 2.6 11.7 4.9 4.1 6.0 0.5 4.9 0.1 12.8 8.1 4.2 12.3 25.3 0.3 17.0 11.5 5.1 33.7 0.1 8.7 43.8 0.6 2.5 2.1 10.6 0.4 1.6 11.7 8.3 3.1 0.4 0.2 0.2 0.7 0.2 0.2 5.1 0.2 7.1 4.0 7.3 2.9 0.5 2.6 10.0 5.4 0.4 7.4 0.2 3.4 6.0 3.5 35.0 36.0 33.9 44.3 37.5 36.7 32.1 30.3 32.0 31.5 35.1 35.1 5.1 6.4 3.9 11.1 6.2 5.7 10.7 14.7 13.1 27.7 27.7 30.6 6.1 14.3 9.3 16.5 29.2 37.1 4.8 0.9 11.7 16.6 2.8 4.1 5.0 6.4 11.4 5.2 20.1 6.4 16.9 8.7 2.6 5.5 8.9 18.0 3.6 9.6 2.9 11.8 22.0 7.8 10.2 0.0 1.9 5.5 23.3 1.1 7.2 2.8 3.4 28.8 5.2 8.5 6.5 5.0 5.5 23.3 5.5 5.5 149.1 25.6 7.4 41.1 0.0 12.1 7.5 3.9 5.2 4.0 3.7 16.3 4.7 15.3 15.0 5.7 TMEM256 "C17orf61, MGC40107" ENSG00000205544 "Transmembrane protein 256" Q8N2U0 17 7402975-7404097 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 573.1;Proximal enterocytes: 972.0;Proximal tubular cells: 801.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062732 Approved Vesicles NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA062732: AB_2684852" "unprognostic (3.82e-2)" "unprognostic (1.93e-1)" "unprognostic (2.91e-1)" "unprognostic (2.77e-2)" "unprognostic (1.05e-1)" "unprognostic (1.74e-3)" "unprognostic (3.69e-2)" "unprognostic (5.73e-2)" "unprognostic (7.45e-2)" "unprognostic (2.12e-2)" "unprognostic (3.22e-2)" "unprognostic (1.91e-1)" "prognostic unfavorable (9.36e-4)" "unprognostic (1.12e-2)" "unprognostic (1.60e-1)" "unprognostic (1.03e-1)" "unprognostic (1.19e-2)" 92.2 84.3 63.9 22.2 66.4 36.7 86.7 67.7 73.0 85.6 63.5 72.6 76.3 63.5 48.2 74.7 77.6 24.0 99.8 62.1 65.2 122.4 173.9 51.8 34.5 67.3 64.2 75.4 113.8 42.6 45.9 14.3 67.1 81.5 25.2 15.1 60.3 24.4 67.4 64.3 90.0 17.6 67.6 67.9 91.7 12.4 64.5 30.8 51.5 41.6 28.5 69.7 67.6 72.4 67.0 89.3 47.3 64.3 78.6 99.0 43.0 30.7 43.9 49.4 46.3 36.1 38.0 59.0 54.0 31.2 39.4 56.4 29.9 93.6 35.7 30.5 99.4 37.5 32.0 95.1 54.0 13.0 49.0 87.1 44.2 64.1 53.0 66.4 73.1 63.8 28.9 39.1 64.1 36.5 44.1 42.5 21.4 29.4 58.6 69.9 41.5 68.8 121.2 28.8 5.5 37.9 47.6 36.7 51.2 46.0 66.6 23.4 43.7 22.8 42.7 46.5 39.3 32.6 45.2 31.2 60.2 18.0 44.4 12.9 63.1 14.8 35.7 48.5 44.5 77.4 42.3 41.3 59.7 69.0 48.5 45.2 3.9 39.3 36.3 82.3 46.0 77.8 63.9 66.4 67.7 73.0 62.1 65.2 67.3 64.2 67.1 67.6 64.5 72.4 103.1 44.8 55.8 0.0 134.5 87.4 93.3 100.1 94.4 24.0 212.4 216.9 62.5 131.5 76.9 132.4 8.4 77.2 78.4 162.9 297.4 132.8 6.0 80.2 84.6 85.1 125.3 100.5 0.0 190.8 223.6 83.3 88.7 84.5 68.4 50.3 114.5 573.1 205.5 20.2 0.0 186.6 81.4 164.7 128.2 6.8 137.3 108.4 144.1 0.0 166.7 134.0 88.6 0.0 0.0 171.3 214.0 71.1 173.1 87.3 972.0 801.9 96.3 42.0 59.2 80.2 160.2 10.1 39.1 179.5 134.0 46.7 91.7 64.5 210.0 90.9 TMEM263 "C12orf23, MGC17943" ENSG00000151135 "Transmembrane protein 263" Q8WUH6 12 106955719-106978778 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014453, HPA042339" Uncertain Approved Vesicles NA NA 14000 "Cluster 40: NK-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA014453: , HPA042339: AB_10795503" "unprognostic (2.56e-2)" "unprognostic (1.41e-1)" "unprognostic (8.99e-2)" "unprognostic (5.65e-2)" "unprognostic (3.90e-1)" "unprognostic (3.46e-2)" "prognostic unfavorable (7.84e-4)" "unprognostic (4.66e-2)" "unprognostic (6.01e-2)" "unprognostic (3.11e-2)" "unprognostic (7.07e-2)" "unprognostic (1.19e-1)" "unprognostic (3.05e-3)" "unprognostic (3.49e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (1.53e-1)" 20.6 27.1 14.5 20.4 15.6 7.4 22.3 14.2 18.2 41.6 21.8 17.8 17.3 28.3 33.4 9.5 16.2 30.4 28.6 15.5 22.1 29.4 44.6 15.3 21.1 13.2 17.1 29.3 23.4 20.7 37.5 43.2 16.5 28.5 19.2 16.8 21.0 21.6 11.5 8.6 15.3 29.9 13.3 16.4 30.9 19.4 21.4 31.0 33.6 14.2 19.7 22.1 13.9 13.5 32.7 28.2 54.1 37.4 125.8 141.6 23.5 123.1 114.0 59.0 74.6 30.1 14.0 3.2 37.5 174.3 33.3 14.9 34.4 48.6 80.9 61.5 38.0 45.5 41.0 65.0 65.1 2.4 28.3 98.6 23.1 63.9 53.8 137.3 73.4 35.1 22.1 12.1 83.6 26.7 35.4 21.4 17.7 21.1 60.3 77.1 41.3 7.9 60.7 27.3 28.2 38.6 67.3 31.2 51.2 41.9 36.5 13.7 86.7 50.6 30.7 66.9 31.6 50.8 31.5 30.3 39.2 7.7 79.4 11.7 1.4 1.6 15.8 1.6 18.3 15.7 15.2 13.7 4.3 16.8 26.8 24.9 1.0 19.8 0.6 14.8 17.4 13.9 14.5 15.6 14.2 18.2 15.5 22.1 13.2 17.1 16.5 13.3 21.4 13.5 31.6 9.6 23.6 12.1 33.5 0.0 52.0 0.0 53.5 24.4 47.7 25.8 55.4 22.8 11.2 23.9 31.3 40.4 54.3 12.4 92.0 19.2 34.8 19.9 75.7 26.4 28.8 10.9 15.4 33.0 72.6 61.5 50.0 32.4 29.9 33.7 33.2 44.4 13.5 11.8 16.5 65.1 0.0 6.7 0.0 37.2 47.2 10.4 0.0 22.5 9.6 34.1 22.6 24.1 8.4 17.3 13.2 43.6 68.3 48.6 23.0 47.7 12.4 21.0 26.3 39.1 41.7 51.2 22.5 12.7 0.0 36.0 36.3 30.6 16.4 44.2 TMEM267 "C5orf28, FLJ21657" ENSG00000151881 "Transmembrane protein 267" Q0VDI3 5 43444252-43483893 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 38.2" "Cell type enhanced" "Detected in many" "Breast glandular cells: 20.2;Collecting duct cells: 16.5;Cytotrophoblasts: 26.3;Distal tubular cells: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059946, HPA072991" Approved Nucleoplasm,Vesicles NA NA "Cluster 44: Non-specific - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Vesicles "HPA059946: AB_2684175, HPA072991: " "unprognostic (8.20e-2)" "unprognostic (2.02e-2)" "unprognostic (7.60e-2)" "unprognostic (8.11e-3)" "unprognostic (1.57e-1)" "unprognostic (2.05e-1)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.82e-2)" "unprognostic (4.77e-3)" "unprognostic (9.32e-2)" "unprognostic (1.76e-1)" "unprognostic (1.25e-1)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.47e-2)" "unprognostic (3.35e-1)" "unprognostic (1.07e-2)" "unprognostic (4.40e-3)" 7.6 7.0 5.7 8.8 5.4 4.9 15.1 5.5 6.2 10.9 7.1 8.4 7.6 8.4 11.9 8.1 8.6 7.7 6.0 5.3 6.5 9.8 7.2 7.6 10.4 5.7 6.6 7.7 7.6 10.7 5.7 6.7 6.5 9.0 9.9 8.1 8.6 9.9 6.2 10.4 6.5 9.6 6.2 8.6 9.9 7.3 5.7 9.2 38.2 3.7 9.6 8.6 6.7 6.4 20.0 18.0 9.5 21.2 17.2 34.8 10.8 28.0 17.3 14.9 10.8 7.9 41.7 21.9 37.7 28.9 15.8 16.3 9.2 12.6 21.3 26.7 14.8 12.9 37.2 8.8 32.0 26.5 17.9 28.9 35.3 22.3 31.7 15.0 16.7 26.3 17.1 39.9 32.8 17.1 14.5 15.3 4.4 20.4 17.4 9.9 23.5 27.3 18.7 20.1 13.2 9.3 56.1 31.5 27.9 8.7 46.0 18.4 21.9 24.0 19.4 14.9 14.1 17.0 26.5 21.6 18.1 37.3 21.6 16.6 11.1 4.4 15.1 13.5 22.3 14.5 20.2 15.9 12.7 13.4 20.3 16.6 1.9 18.9 16.0 9.8 17.5 14.3 5.7 5.4 5.5 6.2 5.3 6.5 5.7 6.6 6.5 6.2 5.7 6.4 9.7 6.4 3.6 0.0 3.0 0.0 0.0 0.0 0.0 0.0 20.2 13.2 0.0 0.0 1.8 16.5 0.0 26.3 6.3 0.0 27.4 13.8 0.0 8.4 9.1 2.6 0.0 0.0 0.0 13.6 10.2 4.5 0.0 9.2 2.5 6.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 13.7 0.0 0.0 0.9 0.0 0.0 13.7 6.6 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 10.5 3.7 6.6 0.0 0.0 TMEM270 "MGC26719, WBSCR28" ENSG00000175877 "Transmembrane protein 270" Q6UE05 7 73861159-73865890 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 215 "testis: 77.6" "Cell type enriched" "Detected in single" 7 "Endometrial ciliated cells: 2.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "MCF7: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA077196 Approved Vesicles NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA077196: AB_2732334" "unprognostic (3.84e-2)" "unprognostic (6.91e-2)" "unprognostic (6.87e-5)" "unprognostic (1.38e-2)" "unprognostic (1.11e-2)" "unprognostic (2.81e-3)" "unprognostic (1.34e-1)" "unprognostic (8.31e-3)" "unprognostic (2.07e-1)" "unprognostic (1.66e-1)" "unprognostic (4.69e-1)" "unprognostic (2.56e-2)" "unprognostic (3.35e-2)" "unprognostic (1.26e-1)" "unprognostic (1.44e-1)" "unprognostic (7.23e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 77.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TMEM35A "FLJ14084, NACHO, TMEM35, TUF-1" ENSG00000126950 "Transmembrane protein 35A" Q53FP2 X 101078879-101096367 "Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.9;intestine: 36.8;seminal vesicle: 50.9" "Cell type enriched" "Detected in some" 5 "Theca cells: 37.5" "Cancer enhanced" "Detected in many" "glioma: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 10.1;HUVEC TERT2: 52.5;SH-SY5Y: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048583 Enhanced Supported Supported "Vesicles,Focal adhesion sites,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 52: Non-specific - Transcription" Vesicles "Focal adhesion sites, Cytosol" "HPA048583: AB_2680451" "unprognostic (7.98e-2)" "unprognostic (7.22e-2)" "unprognostic (1.21e-2)" "unprognostic (1.35e-2)" "unprognostic (3.02e-2)" "unprognostic (3.89e-3)" "unprognostic (2.77e-2)" "unprognostic (6.66e-3)" "unprognostic (1.05e-1)" "unprognostic (3.34e-3)" "unprognostic (9.20e-2)" "unprognostic (4.72e-2)" "unprognostic (3.49e-4)" "unprognostic (5.91e-2)" "unprognostic (1.85e-1)" "unprognostic (1.48e-2)" "unprognostic (9.37e-3)" 3.5 6.9 20.8 1.3 20.4 0.0 0.8 18.5 28.5 4.6 2.5 36.8 3.4 7.8 3.6 11.2 4.1 3.4 0.5 28.4 71.9 0.5 0.0 2.3 0.1 21.8 21.3 7.9 0.2 12.7 2.2 0.1 36.8 22.3 9.6 10.2 0.5 50.9 0.8 0.6 7.2 10.3 15.6 0.8 5.2 1.4 47.5 0.2 0.8 2.5 0.3 9.7 4.4 13.5 0.0 0.0 5.4 0.0 3.9 10.1 0.0 1.1 0.7 0.4 0.2 0.0 0.0 0.0 0.1 3.2 0.0 0.0 3.4 0.0 1.0 0.0 0.2 0.0 0.1 0.0 1.2 0.0 0.0 3.5 0.0 1.9 0.0 7.5 52.5 0.0 0.0 0.1 6.6 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.3 13.2 0.0 0.0 0.0 1.3 0.0 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.8 20.4 18.5 28.5 28.4 71.9 21.8 21.3 36.8 15.6 47.5 13.5 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 7.4 0.4 0.0 0.0 0.0 0.0 0.1 3.0 0.0 0.2 0.0 6.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 37.5 0.0 0.0 TMEM39A "FLJ10902, SUSR2" ENSG00000176142 "Transmembrane protein 39A" Q9NV64 3 119428949-119468830 "Predicted membrane proteins, Transporters" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039140 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Nucleoplasm Vesicles "HPA039140: AB_10673303" "unprognostic (2.16e-1)" "unprognostic (8.75e-2)" "unprognostic (4.25e-2)" "unprognostic (6.86e-2)" "unprognostic (1.56e-2)" "unprognostic (2.81e-1)" "prognostic unfavorable (3.26e-4)" "unprognostic (9.68e-2)" "unprognostic (6.35e-2)" "unprognostic (2.12e-1)" "unprognostic (1.32e-2)" "unprognostic (1.66e-2)" "prognostic unfavorable (1.00e-5)" "unprognostic (4.07e-1)" "unprognostic (2.52e-2)" "unprognostic (1.88e-1)" "unprognostic (6.41e-2)" 12.4 10.5 2.2 14.4 4.3 12.9 10.2 4.1 3.5 19.5 10.9 9.0 10.0 13.2 10.9 9.0 11.7 12.6 11.1 2.2 3.1 6.4 13.0 12.4 10.0 4.0 3.4 13.1 28.4 12.8 15.4 18.1 4.3 9.1 9.3 5.0 13.3 14.3 7.2 8.8 8.0 9.7 3.1 9.2 9.8 7.8 4.7 12.1 16.6 11.9 13.6 14.4 10.5 6.2 28.3 15.1 24.1 17.4 56.1 54.2 24.1 26.4 54.3 37.2 50.0 26.1 21.2 12.0 27.4 28.7 37.9 28.7 29.3 12.1 38.0 12.6 11.2 15.5 13.5 25.4 37.9 27.1 23.4 29.7 20.5 25.9 61.5 37.5 23.6 18.5 16.1 35.5 19.6 14.1 13.7 7.0 20.5 29.8 31.5 16.5 11.3 25.7 9.2 10.7 10.7 15.8 26.6 15.2 33.4 17.3 14.8 23.8 18.5 20.2 17.2 13.8 17.3 39.5 12.5 28.5 27.6 18.2 26.8 12.7 10.9 7.3 11.7 5.8 11.9 7.7 7.1 9.6 12.3 9.0 5.6 6.1 3.8 11.9 4.6 17.3 8.9 9.4 2.2 4.3 4.1 3.5 2.2 3.1 4.0 3.4 4.3 3.1 4.7 6.2 8.5 9.6 15.8 9.8 14.3 22.8 16.0 21.8 8.6 4.7 14.6 10.8 10.8 7.2 16.2 7.3 6.2 26.5 24.7 7.4 5.9 11.6 22.8 8.2 26.3 10.8 10.8 9.0 12.4 14.2 57.6 28.9 13.3 17.9 1.3 13.5 7.9 12.0 13.3 1.7 14.0 18.3 6.1 15.0 54.9 6.8 17.1 17.8 10.6 12.2 31.0 3.9 9.2 25.1 21.8 10.2 6.6 13.2 57.8 20.6 8.0 3.0 14.9 6.4 6.6 15.9 25.2 26.1 18.5 9.6 21.7 59.8 17.4 9.4 11.1 20.4 TMEM39B FLJ10315 ENSG00000121775 "Transmembrane protein 39B" Q9GZU3 1 32072031-32102866 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040191, HPA040224" Approved Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 25: RPMI-8226 - Immune response" "Cluster 10: Non-specific - Unknown function" Vesicles "HPA040191: AB_10805706, HPA040224: AB_10795274" "unprognostic (1.74e-2)" "unprognostic (2.20e-2)" "unprognostic (4.38e-2)" "prognostic unfavorable (3.00e-4)" "unprognostic (1.06e-1)" "unprognostic (1.14e-2)" "prognostic unfavorable (2.82e-6)" "unprognostic (1.10e-2)" "unprognostic (3.37e-2)" "unprognostic (1.74e-1)" "unprognostic (3.63e-2)" "unprognostic (4.47e-2)" "prognostic unfavorable (5.11e-9)" "unprognostic (2.20e-1)" "unprognostic (5.80e-2)" "unprognostic (4.45e-2)" "unprognostic (2.10e-1)" 6.3 4.5 0.8 3.7 0.6 3.8 5.5 0.4 2.6 7.9 0.2 5.8 3.3 8.9 5.5 4.5 5.7 4.4 4.3 0.8 1.1 3.9 5.1 4.7 5.8 1.0 0.8 7.2 3.5 3.6 5.1 5.0 1.0 4.6 3.5 0.6 4.4 5.6 5.2 6.2 4.6 5.8 0.6 5.1 4.5 2.5 1.1 8.4 5.0 3.4 5.4 6.4 5.6 0.8 11.4 3.4 4.6 11.7 13.3 7.7 6.3 9.1 15.7 12.2 11.8 6.9 16.6 13.7 15.5 7.7 7.7 13.1 3.4 14.6 4.0 7.0 10.9 8.2 7.9 3.6 14.8 14.1 9.0 10.7 5.9 18.3 12.7 7.0 8.7 7.9 11.5 11.5 10.4 7.5 11.1 3.9 14.6 13.1 8.7 18.0 15.1 17.0 5.8 6.9 10.6 6.3 12.9 7.7 11.4 2.0 6.2 6.7 10.5 20.5 13.3 7.3 12.0 6.1 7.8 13.0 12.4 12.7 15.4 3.7 22.1 8.4 7.8 18.9 10.6 17.7 11.8 9.7 22.8 16.1 15.2 12.6 6.2 7.7 15.0 33.9 13.8 13.9 0.8 0.6 0.4 2.6 0.8 1.1 1.0 0.8 1.0 0.6 1.1 0.8 12.3 9.6 1.1 4.9 15.3 11.1 14.6 16.2 19.4 8.4 9.7 10.3 2.7 10.0 9.2 3.7 18.8 33.4 17.6 4.7 1.9 8.3 6.7 4.9 10.9 22.0 5.4 6.5 15.8 16.0 22.0 14.1 5.1 7.0 15.2 9.8 14.6 7.0 15.5 6.7 12.3 8.2 12.2 13.5 13.9 2.2 12.2 13.7 10.6 8.4 16.9 4.9 4.1 7.1 12.2 6.3 3.4 13.9 11.4 7.1 6.0 4.4 4.6 5.8 6.6 10.8 17.0 17.4 22.2 14.7 10.2 40.8 8.5 12.6 9.6 7.5 TMEM45A "DERP7, FLJ10134" ENSG00000181458 "Transmembrane protein 45A" Q9NWC5 3 100492619-100577444 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skin 1: 475.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 425.3;Club cells: 841.5;Early spermatids: 207.3;Suprabasal keratinocytes: 254.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 406.9;ASC TERT1: 118.3;HSkMC: 125.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA062101 Uncertain Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 61: Skin - Cornification" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Endoplasmic reticulum" Vesicles "HPA062101: AB_2684682" "unprognostic (5.92e-3)" "unprognostic (5.44e-2)" "unprognostic (2.11e-1)" "unprognostic (1.43e-3)" "unprognostic (7.80e-2)" "unprognostic (1.04e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.42e-4)" "unprognostic (2.37e-1)" "unprognostic (2.21e-2)" "unprognostic (2.43e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (6.18e-11)" "unprognostic (1.24e-3)" "unprognostic (1.11e-1)" "unprognostic (1.02e-5)" "unprognostic (2.68e-2)" 19.4 18.1 1.4 11.7 3.3 2.0 42.8 1.7 2.5 38.4 2.3 10.3 3.6 18.3 3.2 16.5 20.9 18.9 21.9 1.5 1.8 3.7 99.0 13.1 2.6 1.9 1.9 11.9 23.3 2.7 22.9 40.9 1.8 9.1 6.6 1.7 26.9 6.3 3.2 475.1 6.4 25.4 1.7 5.0 7.0 13.3 1.9 1.6 9.1 2.5 50.7 19.5 79.5 2.1 28.6 2.0 2.7 9.6 406.9 118.3 0.3 66.9 62.0 9.4 84.8 2.5 0.6 0.0 32.6 44.1 24.6 31.9 2.4 13.0 23.4 7.2 8.4 23.9 9.3 8.0 25.7 0.4 1.5 125.4 7.4 17.1 25.4 39.0 3.5 0.0 0.6 3.2 22.6 0.3 0.1 0.7 3.2 0.0 16.8 0.0 23.3 0.4 0.6 1.0 2.9 19.4 16.4 8.5 7.3 18.2 0.8 13.6 9.3 62.9 44.3 0.5 15.2 53.8 32.9 0.1 49.7 1.9 42.6 0.0 0.9 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.1 0.1 0.0 0.1 0.5 0.0 0.6 1.4 3.3 1.7 2.5 1.5 1.8 1.9 1.9 1.8 1.7 1.9 2.1 1.6 60.9 61.4 0.7 3.0 94.6 5.4 425.3 9.6 3.2 19.1 8.9 2.5 1.5 841.5 0.0 0.0 2.6 0.4 0.2 0.0 7.5 207.3 3.0 79.1 8.9 1.2 1.3 0.8 14.9 46.3 56.3 2.0 2.0 65.0 10.7 15.0 137.1 5.8 8.4 2.4 2.0 63.1 6.5 25.4 25.4 16.1 6.6 23.2 13.1 1.1 3.5 0.0 16.1 11.8 6.5 2.6 27.8 26.8 3.1 0.3 0.2 121.0 0.9 6.6 22.8 56.6 1.5 3.3 5.4 254.9 7.5 6.4 26.7 0.1 4.4 TMEM54 CAC-1 ENSG00000121900 "Transmembrane protein 54" Q969K7 1 32894594-32901438 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 268.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1231.3;Intestinal goblet cells: 357.2;Paneth cells: 800.1;Proximal enterocytes: 418.6;Undifferentiated cells: 355.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 198.9;OE19: 242.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA060864, HPA061992" Approved Approved Vesicles NA NA "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "HPA060864: , HPA061992: AB_2684652" "unprognostic (2.67e-1)" "unprognostic (2.57e-2)" "unprognostic (2.55e-1)" "unprognostic (4.98e-2)" "unprognostic (3.70e-2)" "unprognostic (3.85e-2)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.31e-1)" "unprognostic (1.04e-1)" "unprognostic (2.42e-2)" "unprognostic (3.48e-2)" "unprognostic (9.43e-2)" "unprognostic (6.82e-3)" "unprognostic (2.13e-2)" "unprognostic (9.06e-2)" "unprognostic (3.12e-2)" "unprognostic (3.40e-2)" 19.2 15.6 68.2 39.9 64.2 0.0 24.6 61.3 98.4 59.0 52.8 268.0 116.0 40.4 26.6 145.3 25.5 62.0 18.7 64.1 70.0 44.3 14.9 26.8 4.6 70.5 68.8 20.3 31.8 49.5 22.6 18.4 64.8 58.2 113.2 4.2 54.0 22.9 6.9 116.0 123.1 21.3 67.8 13.2 108.0 11.9 65.5 2.4 47.8 4.9 13.0 51.1 78.6 66.4 133.3 33.9 0.0 32.0 59.1 35.4 119.9 20.0 29.2 43.1 55.2 84.7 198.9 0.0 57.1 24.8 55.2 80.0 28.6 107.4 12.8 158.3 6.4 0.2 11.3 4.5 42.9 0.4 2.0 30.5 96.2 66.1 18.1 29.1 19.3 13.0 18.7 0.1 22.7 135.6 0.1 2.6 10.3 242.7 60.8 17.7 52.2 0.6 16.2 159.8 1.8 17.1 14.4 82.1 44.0 19.3 89.3 24.2 39.9 42.3 47.5 95.9 40.8 5.2 12.4 15.8 30.1 3.3 61.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.2 64.2 61.3 98.4 64.1 70.0 70.5 68.8 64.8 67.8 65.5 66.4 6.4 19.2 27.6 3.9 6.6 20.4 92.3 36.9 20.5 8.2 82.0 61.0 4.7 97.2 36.9 47.8 4.2 42.8 1.3 1231.3 27.4 150.2 43.4 7.5 16.1 12.3 60.7 0.0 3.3 202.4 149.1 22.9 160.0 14.3 5.7 11.8 18.9 3.7 8.4 0.0 2.9 357.2 12.2 1.0 6.5 32.3 19.9 3.7 14.2 0.0 3.1 33.7 0.0 3.5 2.6 166.3 800.1 24.5 1.6 160.9 418.6 84.9 14.0 10.3 6.6 8.5 20.6 10.9 8.8 65.0 63.6 64.3 3.3 2.4 355.8 193.3 TMEM63A KIAA0792 ENSG00000196187 "Transmembrane protein 63A" O94886 1 225845536-225882380 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 365.5;salivary gland: 121.1" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 323.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 112.2;SK-BR-3: 119.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066504, HPA066936, HPA068918" Enhanced "Vesicles,Centriolar satellite" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 70: Brain - Nervous system development" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Centriolar satellite" "HPA066504: AB_2685680, HPA066936: AB_2685751, HPA068918: AB_2686057" "unprognostic (5.31e-2)" "unprognostic (3.46e-2)" "unprognostic (2.14e-2)" "prognostic favorable (8.79e-4)" "unprognostic (2.05e-1)" "unprognostic (7.16e-3)" "unprognostic (2.52e-2)" "unprognostic (1.76e-2)" "unprognostic (2.57e-1)" "unprognostic (1.27e-1)" "unprognostic (6.55e-2)" "unprognostic (1.59e-1)" "unprognostic (1.19e-1)" "unprognostic (3.14e-2)" "unprognostic (1.62e-1)" "unprognostic (3.35e-1)" "unprognostic (2.92e-2)" 24.5 17.9 58.1 27.0 167.3 42.7 29.1 132.2 120.4 35.9 24.6 33.8 26.3 25.7 22.7 15.2 28.2 27.3 20.9 71.6 94.9 33.3 40.2 31.2 35.6 199.1 127.1 28.4 56.7 17.8 11.8 24.2 191.7 57.6 37.0 3.6 121.1 37.3 16.5 21.5 34.5 18.1 95.7 31.6 47.7 5.3 135.3 27.8 19.0 13.7 27.0 26.4 23.2 365.5 27.6 8.3 7.0 20.2 54.1 18.7 47.7 20.6 22.2 22.5 22.6 29.7 20.0 7.7 37.1 25.2 13.3 41.4 7.5 12.5 10.3 25.8 13.4 33.4 21.0 18.0 12.6 12.5 84.1 19.5 7.8 13.5 8.1 31.1 14.8 17.0 28.2 6.3 18.0 17.4 11.2 12.7 37.8 87.5 13.2 11.1 21.3 112.2 34.1 71.8 0.6 3.7 15.2 119.3 14.5 16.0 27.7 11.9 17.8 12.9 8.9 12.1 18.9 2.5 10.4 2.0 11.9 7.0 24.3 6.3 3.9 3.6 10.3 3.1 11.4 5.8 13.1 9.8 2.9 5.5 11.4 6.9 5.5 10.2 5.3 11.5 19.8 6.9 58.1 167.3 132.2 120.4 71.6 94.9 199.1 127.1 191.7 95.7 135.3 365.5 11.0 6.4 9.2 45.7 23.3 3.3 24.9 5.7 2.2 0.8 30.0 16.8 6.5 34.3 14.0 20.2 2.1 38.7 37.0 34.7 1.9 36.3 9.1 43.1 10.6 8.6 19.2 6.3 1.0 25.5 6.6 8.9 48.9 49.8 17.2 44.8 10.8 22.2 16.7 0.0 1.7 35.0 24.4 11.7 5.3 13.5 18.3 14.2 3.6 26.2 10.4 12.9 40.2 5.5 323.2 18.4 29.0 13.2 9.1 41.6 13.0 14.8 23.1 1.8 26.3 8.8 10.8 0.6 5.3 4.2 4.1 22.4 23.3 7.2 57.6 35.1 TMEM68 FLJ32370 ENSG00000167904 "Transmembrane protein 68" Q96MH6 8 55696424-55773407 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018216, HPA019173" Uncertain Approved Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA018216: AB_2205185, HPA019173: AB_1858129" "unprognostic (4.43e-2)" "unprognostic (3.10e-2)" "unprognostic (8.04e-2)" "unprognostic (2.40e-1)" "unprognostic (4.61e-2)" "unprognostic (1.15e-1)" "unprognostic (3.46e-3)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (3.37e-2)" "unprognostic (3.28e-2)" "unprognostic (1.03e-1)" "unprognostic (3.92e-2)" "unprognostic (1.48e-2)" "unprognostic (1.64e-1)" "unprognostic (4.41e-2)" "unprognostic (1.63e-1)" 8.9 12.9 5.8 8.2 6.5 10.9 13.1 13.2 8.4 10.3 14.5 13.9 12.7 10.5 14.3 13.0 22.0 10.8 6.0 6.6 5.8 17.4 12.8 10.2 9.5 5.2 5.5 13.4 10.6 17.6 5.7 11.9 4.7 13.3 14.5 11.4 12.5 10.2 5.0 14.3 12.8 9.5 4.6 8.3 11.1 8.3 5.6 11.0 16.5 5.3 9.2 11.8 7.6 10.0 22.3 13.4 21.5 13.1 17.0 20.3 38.5 19.6 14.6 18.2 17.1 18.3 41.3 24.0 21.8 12.7 22.5 27.0 17.0 25.5 20.2 33.3 19.2 29.0 12.4 19.5 19.1 12.7 15.7 14.1 38.1 18.4 43.2 26.0 16.3 24.9 29.2 23.6 26.3 11.8 31.8 17.0 24.1 46.1 6.5 22.6 8.9 15.7 29.9 16.9 18.0 16.2 12.6 20.3 39.9 27.7 30.2 16.0 13.2 13.8 17.6 23.6 16.2 20.1 27.4 31.4 18.7 20.6 21.1 35.0 7.6 5.9 7.8 5.0 11.1 10.0 9.1 8.1 8.3 9.7 7.5 10.9 8.4 9.4 9.3 7.6 7.4 4.4 5.8 6.5 13.2 8.4 6.6 5.8 5.2 5.5 4.7 4.6 5.6 10.0 10.5 12.8 12.7 10.7 13.4 34.2 28.0 38.4 19.9 18.2 14.2 12.1 5.2 15.7 30.4 25.8 14.6 32.9 14.6 15.3 13.7 16.4 2.3 42.0 10.4 11.1 15.0 20.0 17.0 8.0 21.1 12.2 13.3 10.4 5.7 12.6 11.4 12.5 13.2 21.9 21.6 26.5 40.7 12.6 11.0 1.2 13.1 9.0 7.2 20.6 13.0 17.2 9.2 26.7 16.9 15.8 21.6 13.9 14.6 26.9 17.4 22.0 66.7 15.3 26.3 9.2 10.8 16.2 15.3 17.5 35.5 22.2 11.7 15.3 15.8 29.3 TMEM87B FLJ14681 ENSG00000153214 "Transmembrane protein 87B" Q96K49 2 112055269-112119318 "Disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 89.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035183 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Golgi apparatus, Vesicles" "HPA035183: AB_10600829" "unprognostic (3.19e-1)" "prognostic unfavorable (3.78e-4)" "unprognostic (1.26e-2)" "unprognostic (1.79e-1)" "unprognostic (1.39e-1)" "prognostic unfavorable (4.28e-4)" "prognostic unfavorable (4.72e-4)" "unprognostic (4.20e-3)" "unprognostic (1.85e-1)" "unprognostic (6.07e-2)" "unprognostic (2.87e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.52e-7)" "unprognostic (1.32e-1)" "unprognostic (5.35e-2)" "unprognostic (1.05e-1)" "unprognostic (3.25e-3)" 10.5 12.2 6.8 14.7 6.6 7.9 20.1 6.1 8.0 12.9 6.9 28.4 28.6 11.0 18.5 10.5 8.4 12.1 5.0 5.9 7.1 7.9 7.4 11.7 15.4 7.5 10.0 6.0 11.3 12.9 9.2 15.1 8.0 30.7 27.8 6.9 15.4 15.9 3.1 13.7 30.5 13.4 7.1 15.5 22.8 5.0 8.3 9.7 15.0 4.2 14.6 17.1 9.0 6.9 21.7 6.4 5.9 25.8 24.9 32.6 21.4 35.5 46.8 21.9 26.7 16.6 28.6 20.9 18.2 47.3 30.2 34.9 3.8 21.6 28.7 12.8 4.1 27.5 4.6 15.2 24.7 19.6 28.9 22.3 25.9 28.0 22.0 21.4 23.6 9.6 16.9 13.1 31.8 13.7 9.3 10.8 4.8 35.0 16.4 7.6 8.9 17.0 20.3 30.2 4.6 6.4 15.4 38.6 34.6 15.5 20.4 14.7 26.6 22.3 6.8 17.6 7.8 10.6 18.1 12.9 25.9 10.1 16.3 5.4 3.0 2.6 3.2 5.2 5.6 5.9 6.9 4.4 2.7 4.9 6.2 3.6 1.8 3.5 6.7 2.7 7.4 3.6 6.8 6.6 6.1 8.0 5.9 7.1 7.5 10.0 8.0 7.1 8.3 6.9 18.3 28.9 13.9 18.9 23.3 12.2 14.5 20.9 39.9 5.0 32.9 14.4 4.6 20.0 21.6 18.4 2.1 15.9 12.3 59.5 0.0 42.9 18.7 14.4 26.5 19.9 17.4 6.3 18.4 89.3 25.5 17.5 46.4 24.9 13.3 14.5 35.7 10.1 21.7 6.7 16.4 53.6 12.2 37.7 10.9 24.5 9.9 22.7 3.6 30.0 20.9 4.0 6.2 21.6 23.1 69.7 47.1 3.0 21.6 28.9 44.9 4.7 17.9 7.9 0.0 5.4 17.2 4.9 5.6 29.9 12.8 29.1 20.5 11.8 38.2 23.9 TMEM8B "C9orf127, FP588, LINC00950, NAG-5, NGX6, NGX6a" ENSG00000137103 "Transmembrane protein 8B" A6NDV4 9 35814451-35865518 "Predicted membrane proteins, Transporters" "Cell adhesion, Growth regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 36.1;Granulosa cells: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 51.2" "Lineage enriched" "Detected in many" 24 "dendritic cells: 51.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052130, HPA062701" Approved Approved Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA052130: AB_2681740, HPA062701: AB_2684839" "unprognostic (5.54e-2)" "unprognostic (3.32e-1)" "unprognostic (3.96e-1)" "unprognostic (3.53e-2)" "unprognostic (3.81e-1)" "unprognostic (1.42e-1)" "unprognostic (4.09e-2)" "unprognostic (2.67e-2)" "unprognostic (2.97e-1)" "unprognostic (1.62e-1)" "prognostic favorable (3.14e-4)" "unprognostic (5.93e-2)" "prognostic favorable (1.89e-15)" "unprognostic (8.00e-2)" "unprognostic (1.26e-1)" "unprognostic (1.68e-2)" "unprognostic (3.29e-2)" 10.4 21.1 19.9 3.1 16.0 1.8 12.3 11.5 20.7 21.7 3.6 19.9 5.1 20.1 6.2 5.7 20.8 6.7 15.9 20.3 13.9 15.8 6.4 10.2 3.6 14.2 15.3 33.6 11.8 17.8 30.6 4.5 13.9 23.9 5.5 7.7 18.1 14.2 12.8 9.3 9.5 6.9 12.7 8.5 17.7 19.1 18.5 5.2 22.7 9.6 2.6 19.3 15.7 12.4 3.1 3.4 11.7 9.2 12.9 10.7 1.4 2.8 5.5 3.1 3.8 1.4 0.8 2.5 6.5 7.7 9.1 1.2 3.1 4.7 2.5 1.9 5.2 0.7 2.5 3.4 9.1 0.2 0.2 10.1 6.1 3.2 3.4 10.0 1.8 11.5 1.2 6.9 5.5 1.2 6.6 1.4 1.6 2.7 4.6 7.2 2.4 6.2 3.3 1.5 2.8 8.1 4.3 1.8 4.1 3.8 3.2 1.1 2.9 7.3 2.2 7.2 1.1 8.6 2.8 2.8 6.7 1.2 4.6 0.7 2.1 0.2 0.5 0.1 0.3 0.6 0.4 0.4 8.2 0.5 0.4 0.4 0.9 0.7 0.1 51.2 0.2 1.3 19.9 16.0 11.5 20.7 20.3 13.9 14.2 15.3 13.9 12.7 18.5 12.4 4.4 12.8 12.2 18.9 3.3 4.5 9.1 8.1 8.0 4.1 12.1 11.4 11.7 10.0 9.1 14.7 2.1 34.1 36.1 8.2 1.9 5.7 25.4 7.7 8.4 3.2 6.7 0.8 12.4 4.0 9.2 9.2 11.2 6.3 1.3 47.3 1.8 4.0 3.2 1.7 13.0 7.0 12.2 1.3 11.2 14.0 14.6 5.3 10.6 10.3 3.6 9.1 2.1 12.1 7.2 3.6 8.0 19.5 2.6 9.0 3.0 4.5 7.5 5.3 6.6 7.1 8.7 8.6 5.2 1.9 1.6 13.0 3.6 8.1 7.8 10.0 TMEM9 TMEM9A ENSG00000116857 "Transmembrane protein 9" Q9P0T7 1 201134772-201171574 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008483 Approved "Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA008483: " "unprognostic (1.88e-1)" "prognostic unfavorable (6.57e-4)" "unprognostic (2.95e-1)" "unprognostic (3.67e-2)" "unprognostic (3.96e-1)" "prognostic unfavorable (3.93e-4)" "unprognostic (1.05e-2)" "unprognostic (1.47e-1)" "unprognostic (1.53e-2)" "unprognostic (1.69e-2)" "unprognostic (2.46e-2)" "unprognostic (2.99e-1)" "unprognostic (1.88e-2)" "unprognostic (2.38e-1)" "unprognostic (9.17e-2)" "unprognostic (3.32e-1)" "unprognostic (9.90e-2)" 34.1 102.3 103.1 20.8 104.4 27.8 45.0 93.5 126.6 76.8 122.7 45.0 25.4 70.9 65.4 31.1 75.4 39.5 51.3 107.8 113.2 73.8 73.8 44.5 23.5 99.4 111.5 81.4 73.9 92.2 63.4 28.5 102.8 60.3 25.4 43.9 60.7 45.9 44.9 35.5 30.4 37.5 100.2 31.2 49.8 67.0 112.5 26.3 68.5 24.9 17.7 45.7 51.8 100.2 63.1 117.0 72.6 168.9 38.5 54.5 128.5 48.6 51.5 76.0 68.2 115.7 99.8 33.2 69.2 73.4 70.1 123.3 76.5 80.1 37.3 21.3 131.9 58.1 182.4 76.6 73.8 28.2 51.9 65.0 87.0 71.2 43.0 91.3 47.7 46.2 105.6 35.5 66.2 81.0 34.1 46.1 111.0 57.3 285.3 60.7 108.4 44.0 87.9 48.0 67.6 137.7 86.7 146.9 91.8 107.4 180.3 48.5 35.7 84.8 70.0 68.5 59.8 143.9 135.2 26.1 64.4 30.1 42.0 49.8 59.8 33.7 45.7 41.8 52.2 54.5 44.0 37.8 51.5 49.2 64.6 42.7 41.0 32.9 38.5 56.1 43.0 75.5 103.1 104.4 93.5 126.6 107.8 113.2 99.4 111.5 102.8 100.2 112.5 100.2 20.9 51.3 49.5 17.0 13.4 12.9 31.4 65.6 27.3 61.0 56.2 65.7 39.3 40.0 48.0 36.8 31.3 44.4 9.3 7.9 17.6 88.8 58.0 37.3 58.6 26.3 31.8 43.6 15.7 74.7 52.1 59.9 20.9 46.4 13.3 46.3 30.0 40.4 28.1 8.4 22.1 26.9 36.7 13.4 11.9 60.9 70.8 15.6 23.2 8.4 11.8 102.3 25.7 15.6 10.1 40.3 18.8 53.0 18.8 28.5 8.3 56.9 54.5 32.8 13.1 33.3 42.1 54.8 76.7 14.5 13.9 13.0 13.0 130.7 28.4 27.8 TMIE DFNB6 ENSG00000181585 "Transmembrane inner ear" Q8NEW7 3 46694528-46710886 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.6;choroid plexus: 10.5;pituitary gland: 9.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 3.8;Spermatocytes: 2.6;Spermatogonia: 3.2" "Cancer enriched" "Detected in many" 5 "glioma: 6.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 2.4" "Lineage enriched" "Detected in single" 15 "T-cells: 2.4" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.1;EFO-21: 2.7;JURKAT: 10.7;SH-SY5Y: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038298 Uncertain Uncertain Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Cytosol" "HPA038298: AB_10675792" "unprognostic (6.59e-2)" "unprognostic (1.11e-1)" "unprognostic (7.25e-3)" "unprognostic (2.48e-3)" "unprognostic (1.88e-2)" "unprognostic (5.40e-3)" "unprognostic (3.94e-2)" "unprognostic (8.80e-2)" "unprognostic (3.37e-2)" "unprognostic (6.65e-2)" "unprognostic (1.97e-1)" "unprognostic (5.35e-2)" "unprognostic (4.58e-2)" "unprognostic (1.23e-1)" "unprognostic (4.41e-2)" "unprognostic (5.29e-2)" "unprognostic (6.78e-2)" 0.7 6.2 14.2 0.5 14.1 0.0 0.4 14.0 18.0 0.7 10.5 1.0 0.4 0.5 0.7 1.5 0.6 0.2 0.7 14.1 19.3 2.3 0.8 1.0 0.8 19.6 15.7 1.5 0.2 0.1 9.9 0.4 19.2 0.5 0.3 0.7 0.5 1.0 3.6 0.7 0.5 0.4 16.0 0.7 0.3 1.5 18.7 0.5 0.9 1.2 0.8 0.6 0.9 14.9 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.1 0.0 2.7 0.0 0.5 0.1 0.1 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.8 0.0 0.0 0.0 1.8 0.0 1.2 0.0 0.5 10.7 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.7 0.1 1.2 0.0 0.3 0.1 0.1 0.3 2.3 0.3 0.3 0.0 0.1 0.0 0.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.1 0.0 2.4 0.4 0.0 0.0 0.0 0.0 0.4 0.4 14.2 14.1 14.0 18.0 14.1 19.3 19.6 15.7 19.2 16.0 18.7 14.9 1.9 0.0 0.0 0.3 0.0 0.8 0.2 0.5 0.0 3.8 0.2 0.6 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.1 1.9 0.4 0.5 0.2 0.0 0.7 0.0 0.0 1.7 0.4 0.1 0.4 0.0 0.1 0.0 0.1 0.4 0.1 0.6 0.0 0.8 0.0 0.0 0.0 0.4 1.5 0.6 0.3 0.0 1.9 0.1 1.4 0.0 0.0 0.3 1.2 0.0 0.4 0.0 0.3 0.0 0.0 0.6 0.5 0.0 1.1 1.0 2.6 3.2 0.0 0.9 0.1 0.2 0.1 0.0 0.2 TMSB4X "TB4X, TMSB4" ENSG00000205542 "Thymosin beta 4 X-linked" P62328 X 12975110-12977227 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 30742.3;Langerhans cells: 57681.0;monocytes: 48133.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB033806 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Vesicles, Cytosol" "CAB033806: AB_2256019" "unprognostic (1.60e-1)" "unprognostic (1.00e-1)" "unprognostic (4.09e-3)" "unprognostic (1.16e-3)" "unprognostic (8.72e-2)" "unprognostic (3.27e-2)" "unprognostic (7.98e-3)" "unprognostic (1.71e-2)" "unprognostic (2.75e-1)" "unprognostic (2.28e-2)" "unprognostic (1.66e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (6.20e-4)" "unprognostic (5.98e-2)" "unprognostic (2.68e-1)" "unprognostic (3.77e-2)" "unprognostic (1.98e-1)" 6173.6 4217.0 3255.7 5088.7 3773.0 8722.4 4452.0 3539.2 4521.9 3685.7 2999.1 4327.1 1776.8 3731.3 2877.9 2069.6 2709.3 4129.3 2652.4 3319.4 3573.5 3300.1 2360.4 6225.5 10448.1 4064.7 3620.0 2592.1 1852.6 483.2 1053.7 2450.2 4203.0 2335.6 3793.9 273.3 1886.8 2441.9 816.5 1962.4 3671.2 3340.7 4219.2 7935.5 4690.0 486.8 3591.8 6377.6 1648.7 1475.0 7233.8 5168.6 2907.2 4467.6 5980.6 4886.3 9387.7 14881.1 11264.5 12247.2 23.0 3083.9 8032.6 2344.3 4005.4 1016.1 4865.3 1417.1 2900.6 9443.7 4198.0 2564.2 1411.5 2072.7 3135.4 8343.4 80.9 1771.0 2621.8 12.9 2619.8 6994.8 14038.1 5755.3 2911.9 2781.9 2412.7 5704.5 14335.9 3714.1 230.0 22.0 8424.8 2121.5 8390.5 15083.5 3384.1 2853.1 3337.3 6352.0 3321.0 5858.5 14234.5 1720.4 994.2 422.9 4461.8 207.4 583.3 6898.2 5536.5 6961.4 11607.2 3383.5 1647.5 19441.4 3123.6 4432.5 3490.6 2774.8 5183.2 2860.5 2499.5 42940.3 34738.5 50992.6 21474.2 33907.1 18326.4 18757.1 23777.1 23343.2 31253.2 16919.4 19802.1 20330.2 35862.9 18444.5 37523.3 12797.6 34088.1 86809.5 3255.7 3773.0 3539.2 4521.9 3319.4 3573.5 4064.7 3620.0 4203.0 4219.2 3591.8 4467.6 6885.8 5253.2 4939.6 35.9 6293.8 8836.3 2708.7 10515.3 296.5 332.9 2318.3 1124.2 106.9 3484.4 8003.6 6882.2 22.9 283.0 9136.2 9016.2 2181.5 17304.6 142.1 2613.2 4698.0 9239.4 1765.0 1339.1 54.3 23029.4 511.7 4800.1 2728.9 5047.4 4380.4 4646.7 6638.0 1088.5 30742.3 62.2 81.0 4883.9 14806.8 20982.2 57681.0 343.6 3932.0 17648.1 6349.9 212.7 48133.8 86.7 20882.8 19.6 102.1 25113.5 5826.4 6035.9 2541.8 3272.5 6888.7 835.1 2596.4 99.4 5732.4 1018.2 5450.7 58.2 126.3 933.7 9528.5 454.8 12719.6 3874.8 3140.6 9064.0 TMTC4 "FLJ14624, FLJ22153" ENSG00000125247 "Transmembrane O-mannosyltransferase targeting cadherins 4" Q5T4D3 13 100603625-100675093 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 139.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016489, HPA057056" Approved Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 28: BEWO - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA016489: AB_1858157, HPA057056: " "unprognostic (1.49e-1)" "unprognostic (1.87e-1)" "unprognostic (8.34e-2)" "unprognostic (1.35e-1)" "unprognostic (2.43e-2)" "unprognostic (1.96e-1)" "unprognostic (1.50e-2)" "unprognostic (1.96e-1)" "unprognostic (1.88e-2)" "unprognostic (1.09e-1)" "unprognostic (3.11e-1)" "unprognostic (2.34e-1)" "unprognostic (1.41e-1)" "unprognostic (1.99e-1)" "unprognostic (6.04e-2)" "unprognostic (9.18e-2)" "unprognostic (2.65e-2)" 5.2 4.2 13.4 5.9 22.9 3.1 6.5 18.9 34.0 6.9 11.5 8.4 9.9 9.6 8.0 5.1 14.3 5.7 4.0 14.0 16.0 12.5 11.3 4.3 4.8 21.6 19.4 6.1 10.5 10.7 3.3 5.0 21.9 8.7 8.5 10.0 8.7 6.0 13.6 7.4 8.6 7.0 17.9 4.3 9.2 11.8 19.1 7.1 8.1 8.7 5.7 7.7 4.6 32.2 10.4 7.7 42.2 21.2 5.7 10.5 44.6 5.5 5.0 5.0 4.1 8.1 17.5 29.6 18.4 5.0 12.0 6.8 13.5 7.8 6.6 16.9 9.3 12.6 15.4 13.0 7.1 15.7 0.4 14.7 11.1 2.2 8.8 14.8 23.5 16.1 9.5 3.7 5.7 9.2 12.5 9.0 11.3 27.8 7.8 13.9 7.7 6.8 19.8 7.4 21.1 21.9 11.1 19.7 5.3 26.0 14.6 44.6 36.6 4.8 8.2 4.1 9.7 9.5 9.1 5.8 22.4 9.9 13.5 0.0 1.1 0.1 1.3 1.2 1.1 1.0 1.3 2.1 3.3 1.2 1.5 0.5 0.0 0.7 1.8 2.3 2.1 0.8 13.4 22.9 18.9 34.0 14.0 16.0 21.6 19.4 21.9 17.9 19.1 32.2 4.7 6.4 3.9 18.9 4.5 3.1 7.2 4.2 3.4 19.0 10.7 4.1 11.3 18.6 6.2 5.5 8.4 11.6 5.6 7.7 1.9 11.6 5.8 12.2 9.7 8.4 10.7 5.0 11.1 18.7 19.8 6.2 6.1 14.4 0.0 12.8 39.7 15.3 4.3 26.9 19.4 10.1 2.0 6.9 2.5 6.2 4.1 3.7 3.6 9.4 3.3 8.2 5.2 15.1 139.6 13.0 7.4 6.8 3.6 10.9 10.5 14.2 6.8 8.6 6.6 4.2 5.8 9.7 32.3 7.9 5.8 3.1 4.1 5.3 11.7 5.3 TMUB2 MGC3123 ENSG00000168591 "Transmembrane and ubiquitin like domain containing 2" Q71RG4 17 44186970-44191929 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043137 Approved Approved Vesicles,Cytosol NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Vesicles, Cytosol" "HPA043137: AB_10794388" "unprognostic (4.57e-2)" "unprognostic (1.58e-2)" "unprognostic (6.06e-2)" "unprognostic (1.26e-2)" "unprognostic (6.37e-2)" "unprognostic (1.85e-2)" "unprognostic (6.43e-3)" "unprognostic (1.07e-1)" "unprognostic (2.05e-1)" "unprognostic (3.35e-2)" "unprognostic (1.80e-1)" "unprognostic (1.58e-1)" "unprognostic (2.12e-1)" "unprognostic (9.75e-3)" "unprognostic (3.67e-2)" "unprognostic (2.12e-1)" "unprognostic (2.78e-3)" 32.2 35.7 34.1 22.9 34.4 43.9 32.5 34.9 38.1 37.3 32.5 39.1 24.5 32.5 21.9 37.3 33.9 25.2 33.1 34.2 32.8 36.9 35.8 31.5 26.3 33.6 33.8 35.2 36.9 27.5 32.9 25.9 32.9 42.0 21.9 16.8 36.1 26.3 32.7 32.4 36.5 21.7 32.2 52.8 36.7 46.8 34.2 23.2 42.7 20.0 20.5 35.3 34.3 34.3 22.8 43.0 27.6 25.1 41.6 32.8 21.6 29.5 31.6 53.7 54.4 22.7 41.5 15.8 31.1 36.1 40.5 42.3 19.3 28.0 33.4 38.7 39.7 16.5 40.9 35.1 43.8 18.7 35.5 40.1 39.8 36.9 22.9 45.1 37.8 25.8 19.2 45.4 35.7 15.9 26.0 23.8 9.1 19.0 35.7 23.2 33.3 25.5 33.8 25.2 21.8 22.2 15.5 14.4 29.4 27.6 42.2 23.0 31.8 44.4 27.0 31.1 26.7 33.5 26.1 15.4 34.0 15.7 30.4 84.1 30.0 57.3 17.1 26.7 14.5 16.6 14.3 16.5 19.1 23.8 13.4 15.3 65.4 13.9 29.0 23.1 18.1 20.4 34.1 34.4 34.9 38.1 34.2 32.8 33.6 33.8 32.9 32.2 34.2 34.3 24.8 35.3 25.9 21.2 40.8 13.0 21.2 27.0 25.6 30.8 29.8 25.3 16.7 22.8 27.2 22.0 31.3 46.3 24.9 42.5 3.9 21.0 51.0 13.9 16.8 20.4 33.5 25.7 15.8 18.8 29.6 22.0 23.0 25.1 22.1 25.6 18.9 13.9 42.6 21.9 16.4 27.1 12.2 37.9 25.9 28.4 21.8 30.9 14.2 16.9 31.5 29.1 25.7 14.6 12.2 25.8 33.2 24.0 18.8 20.5 39.6 10.7 18.9 27.9 26.3 14.6 19.6 81.5 37.1 17.2 14.9 96.7 27.6 30.0 27.0 23.4 TNFAIP8L2 FLJ23467 ENSG00000163154 "TNF alpha induced protein 8 like 2" Q6P589 1 151156649-151159749 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 70.4;Kupffer cells: 65.4;Macrophages: 35.8;monocytes: 34.7;NK-cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 29.8;HL-60: 17.6;HMC-1: 44.1;NB-4: 25.2;THP-1: 95.2;U-937: 37.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062742 Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "HPA062742: " "unprognostic (3.19e-3)" "unprognostic (1.02e-2)" "unprognostic (6.63e-3)" "unprognostic (2.27e-2)" "unprognostic (1.29e-1)" "unprognostic (6.49e-3)" "unprognostic (1.05e-1)" "unprognostic (9.15e-3)" "prognostic favorable (3.64e-4)" "unprognostic (9.54e-2)" "unprognostic (3.32e-2)" "unprognostic (9.03e-2)" "prognostic unfavorable (3.53e-7)" "unprognostic (1.78e-1)" "unprognostic (3.91e-2)" "unprognostic (4.87e-2)" "unprognostic (2.23e-1)" 4.7 4.3 4.9 19.6 5.4 6.1 3.4 5.1 7.5 2.3 5.7 4.5 5.3 1.5 1.4 2.5 2.2 5.5 2.3 4.7 5.2 2.0 5.6 10.8 32.0 6.5 5.7 1.0 1.4 1.2 1.2 6.9 7.0 2.1 6.1 0.9 2.6 1.8 0.8 3.8 7.6 5.4 6.4 39.2 3.4 0.8 6.3 19.2 1.3 2.2 17.7 7.8 1.4 8.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 29.8 0.4 0.0 0.0 17.6 44.1 0.0 0.0 0.0 0.0 0.0 0.4 2.5 0.1 0.1 0.0 0.1 0.4 25.2 0.0 0.0 0.1 5.3 0.1 4.1 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 95.2 2.5 0.2 0.1 0.1 0.2 0.3 0.0 1.9 0.1 37.8 0.1 317.0 238.8 246.7 103.2 220.2 101.9 78.3 125.7 105.2 265.4 83.2 189.5 137.3 292.3 232.9 210.6 63.0 155.7 249.5 4.9 5.4 5.1 7.5 4.7 5.2 6.5 5.7 7.0 6.4 6.3 8.1 0.3 0.0 1.7 0.0 6.9 0.3 0.0 0.0 0.0 0.8 0.8 0.3 0.1 2.8 1.3 0.0 0.0 0.3 11.1 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 8.8 0.0 0.0 0.5 0.2 0.0 0.0 5.1 0.0 0.7 0.3 70.4 0.0 0.0 0.0 0.0 65.4 12.8 0.4 0.3 35.8 0.0 0.0 34.7 0.0 48.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 1.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.4 10.6 0.0 0.0 0.0 TNFSF12 "APO3L, DR3LG, TWEAK" ENSG00000239697 "TNF superfamily member 12" O43508 17 7549058-7557890 "Predicted secreted proteins" "Angiogenesis, Apoptosis, Differentiation" "Cytokine, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 115.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 17.7;BJ hTERT+: 18.4;HDLM-2: 20.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035984, HPA052967" Uncertain Approved Vesicles "Secreted to blood" NA NA 853000 130000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA035984: , HPA052967: AB_2682000" "unprognostic (2.96e-3)" "unprognostic (2.96e-1)" "unprognostic (4.71e-2)" "prognostic favorable (5.70e-5)" "unprognostic (5.31e-2)" "unprognostic (7.91e-2)" "unprognostic (6.45e-2)" "unprognostic (2.38e-2)" "unprognostic (4.48e-2)" "unprognostic (6.09e-2)" "unprognostic (6.20e-2)" "unprognostic (8.62e-2)" "unprognostic (3.29e-2)" "unprognostic (4.11e-2)" "unprognostic (3.15e-2)" "unprognostic (8.74e-2)" "unprognostic (2.38e-1)" 41.6 28.5 57.4 9.8 55.3 3.1 36.6 49.4 66.5 37.6 48.9 68.2 9.7 38.2 7.0 13.9 37.7 15.6 39.6 54.8 50.4 32.9 16.5 37.7 15.8 55.7 54.2 42.7 23.2 11.1 18.0 11.2 53.2 39.4 5.7 2.9 26.1 27.2 16.9 15.8 26.7 13.3 52.8 38.4 38.8 5.6 57.0 4.8 22.9 9.3 5.5 47.1 30.1 52.1 0.0 0.5 0.7 0.0 14.9 17.7 4.0 6.9 18.4 7.7 5.7 0.1 2.5 0.0 5.8 16.3 0.8 1.4 1.4 0.6 1.6 20.3 2.0 0.9 0.4 2.3 12.8 0.0 0.0 15.0 2.6 2.8 0.3 3.0 12.1 0.0 0.0 0.0 7.0 0.0 0.0 0.5 0.6 0.1 7.5 0.1 0.0 0.1 11.6 0.0 0.0 7.9 2.5 0.0 12.6 0.1 1.4 0.6 16.1 15.1 1.1 0.1 8.8 0.0 0.0 0.0 2.4 0.0 10.5 2.6 3.5 11.6 5.1 5.9 6.0 2.9 4.3 3.1 2.2 1.8 4.1 4.2 2.0 2.8 1.5 2.5 4.0 1.1 57.4 55.3 49.4 66.5 54.8 50.4 55.7 54.2 53.2 52.8 57.0 52.1 115.9 9.6 12.2 0.0 20.4 6.1 11.1 1.5 6.8 6.7 21.7 41.7 4.3 17.2 3.4 16.5 0.0 1.6 38.3 2.5 7.9 15.2 0.4 4.1 15.2 33.9 1.2 3.2 0.0 12.1 0.8 42.7 4.6 8.5 34.3 6.8 48.5 3.4 44.3 20.2 0.0 3.4 0.0 59.7 26.8 1.2 50.7 62.1 19.6 0.0 28.6 46.6 40.2 0.0 0.0 8.1 1.7 50.4 3.6 6.7 0.4 39.6 0.6 2.6 59.2 34.4 56.7 0.2 1.1 2.1 7.5 0.8 38.7 9.4 4.1 6.0 TNFSF12-TNFSF13 TWE-PRIL ENSG00000248871 "TNFSF12-TNFSF13 readthrough" 17 7549099-7561601 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 9.1;choroid plexus: 5.7" "Group enriched" "Detected in some" 17 "Alveolar cells type 2: 3.7;Club cells: 3.7;granulocytes: 3.8;Macrophages: 4.5;Respiratory ciliated cells: 1.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 7.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.7;fHDF/TERT166: 1.3;HUVEC TERT2: 1.1;U-138 MG: 1.7;U-251 MG: 1.7" "Low region specificity" "Detected in all" "HPA004863, HPA035984, HPA052967" Uncertain Approved Vesicles "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA004863: AB_1078187, HPA035984: , HPA052967: AB_2682000" "unprognostic (1.59e-1)" "unprognostic (1.48e-1)" "unprognostic (2.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.13e-1)" "unprognostic (1.36e-1)" "unprognostic (3.04e-1)" "unprognostic (2.19e-1)" "unprognostic (1.05e-2)" "unprognostic (1.40e-1)" "unprognostic (8.96e-3)" "unprognostic (1.38e-2)" "unprognostic (2.05e-1)" "unprognostic (8.23e-2)" 4.0 1.3 4.7 0.7 4.7 0.7 1.8 4.5 9.1 0.7 5.7 1.4 0.2 0.4 0.0 0.3 0.4 0.1 2.3 4.5 5.0 2.3 0.7 4.6 1.0 5.1 5.1 0.4 0.5 0.1 0.4 0.2 4.7 0.7 0.0 0.1 0.6 0.2 0.7 0.8 0.8 0.3 4.6 3.1 0.7 0.1 5.0 0.2 0.4 0.0 0.5 1.1 0.3 4.8 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.5 1.7 0.6 0.9 0.0 0.0 0.0 0.2 1.3 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.3 0.3 0.0 0.0 1.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.8 0.1 0.0 0.5 0.0 0.0 0.0 0.5 1.7 0.0 0.0 1.7 0.0 0.0 0.0 0.4 0.0 0.2 0.4 2.4 7.2 0.2 4.5 0.3 0.7 0.5 0.3 1.8 1.5 0.3 0.1 0.3 0.2 0.2 0.9 1.0 1.4 4.7 4.7 4.5 9.1 4.5 5.0 5.1 5.1 4.7 4.6 5.0 4.8 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 TNFSF13B "BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20" ENSG00000102524 "TNF superfamily member 13b" Q9Y275 13 108251240-108308484 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 87.5;Kupffer cells: 141.1;Langerhans cells: 246.7;Macrophages: 170.4;monocytes: 509.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 505.4" "Group enriched" "Detected in all" 11 "dendritic cells: 206.4;granulocytes: 505.4;monocytes: 350.9" "Cell line enriched" "Detected in some" 7 "U-937: 167.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB009188, HPA030526" Enhanced Supported "Vesicles,Plasma membrane,Focal adhesion sites" "Secreted to blood" NA NA 393000 790000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Vesicles, Focal adhesion sites" "CAB009188: , HPA030526: " "unprognostic (6.48e-2)" "unprognostic (3.05e-3)" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" "unprognostic (2.61e-2)" "unprognostic (7.99e-2)" "unprognostic (8.19e-2)" "unprognostic (1.37e-1)" "unprognostic (1.63e-1)" "unprognostic (1.02e-2)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.53e-11)" "unprognostic (1.23e-1)" "unprognostic (4.14e-2)" "unprognostic (1.88e-1)" "unprognostic (1.25e-1)" 8.2 5.3 2.8 25.9 2.6 20.1 4.7 2.7 4.1 2.2 5.8 5.5 10.7 1.4 1.5 4.8 2.4 12.4 3.8 2.7 3.1 1.5 5.3 10.9 20.9 6.3 3.0 1.1 1.5 0.7 1.0 9.0 4.2 1.7 8.4 0.4 3.3 1.2 1.4 1.9 6.4 5.0 4.6 15.9 5.0 1.2 3.5 5.3 3.0 1.6 17.7 11.1 2.1 5.2 0.1 0.4 0.1 0.1 0.7 0.8 0.2 0.3 0.8 0.6 2.1 0.1 1.7 0.3 0.2 0.2 0.3 0.1 0.0 0.1 0.1 11.6 0.0 0.9 0.4 0.0 0.4 10.2 0.3 2.0 0.4 0.2 0.1 0.4 0.1 0.1 0.1 0.6 1.2 0.0 0.1 5.3 0.1 1.1 0.0 0.0 0.2 0.0 0.6 0.3 1.3 0.3 0.0 0.0 0.4 0.2 0.1 22.3 0.2 0.3 0.0 0.0 0.4 10.0 0.3 0.1 10.3 167.0 1.7 12.6 350.9 100.1 5.4 272.3 31.5 4.4 21.5 4.4 206.4 7.1 9.9 3.4 505.4 5.0 234.1 77.8 19.4 165.8 2.8 2.6 2.7 4.1 2.7 3.1 6.3 3.0 4.2 4.6 3.5 5.2 3.1 16.0 12.9 6.2 7.0 7.1 0.7 1.3 1.2 0.9 2.4 3.2 0.6 10.0 4.2 5.5 0.0 0.5 40.6 0.6 1.9 2.3 1.2 0.4 0.7 3.6 1.2 14.5 18.1 32.5 1.1 29.6 3.1 0.5 5.1 0.9 3.9 2.8 87.5 0.0 11.2 0.9 0.0 141.1 246.7 0.6 5.3 170.4 8.8 15.0 509.4 0.2 5.2 55.3 5.1 1.7 0.5 1.9 1.5 2.7 2.2 1.3 2.0 0.3 6.6 1.4 4.1 0.1 0.7 0.5 4.7 1.1 10.5 1.2 1.8 3.1 TNFSF14 "CD258, HVEM-L, LIGHT, LTg" ENSG00000125735 "TNF superfamily member 14" O43557 19 6661253-6670588 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 29.0;liver: 107.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 26.3;dendritic cells: 40.5;granulocytes: 26.1;Macrophages: 20.0;NK-cells: 26.8;T-cells: 43.7" "Cancer enhanced" "Detected in many" "liver cancer: 4.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 199.7" "Group enriched" "Detected in all" 4 "granulocytes: 199.7;T-cells: 61.2" "Cell line enhanced" "Detected in some" "HDLM-2: 16.9;NB-4: 4.9;THP-1: 3.1;U-937: 10.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA012700 Uncertain Approved Vesicles "Secreted to blood" NA NA 41000 "Cluster 5: Granulocytes - Unknown function" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA012700: AB_1852870" "unprognostic (2.78e-3)" "unprognostic (2.11e-1)" "unprognostic (1.62e-1)" "unprognostic (2.35e-3)" "unprognostic (3.82e-4)" "unprognostic (4.51e-2)" "unprognostic (1.09e-1)" "unprognostic (2.63e-1)" "unprognostic (1.05e-2)" "unprognostic (9.23e-2)" "unprognostic (9.22e-2)" "unprognostic (3.59e-1)" "prognostic unfavorable (6.07e-13)" "unprognostic (1.09e-1)" "unprognostic (9.56e-3)" "unprognostic (1.75e-1)" "unprognostic (3.62e-2)" 29.0 1.7 2.2 3.1 1.3 1.9 2.7 0.8 6.4 2.1 1.3 2.7 1.8 0.9 0.3 1.8 9.7 1.2 3.8 1.0 1.2 1.3 107.9 4.9 2.5 1.3 1.7 5.1 4.5 0.0 1.1 0.2 1.7 2.0 1.3 0.2 2.2 0.2 0.5 0.6 5.9 1.2 0.9 3.2 2.3 0.6 3.1 1.1 2.8 0.6 2.0 4.1 2.3 1.7 0.0 0.3 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.5 0.0 0.0 0.0 16.9 0.0 0.0 0.2 1.1 0.0 0.5 0.4 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 3.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 10.4 0.0 140.9 17.6 115.3 41.8 4.0 61.2 0.4 17.7 34.5 6.9 1.9 2.8 15.0 199.7 30.7 0.5 0.7 15.9 12.8 2.2 1.3 0.8 6.4 1.0 1.2 1.3 1.7 1.7 0.9 3.1 1.7 0.7 9.6 26.3 0.0 1.6 2.9 0.7 0.9 0.0 0.0 1.1 0.8 0.8 15.7 8.2 0.0 0.0 0.1 40.5 0.0 0.0 4.1 1.2 4.8 2.6 0.9 0.0 0.4 0.1 3.8 0.2 12.4 1.1 18.1 26.1 0.2 1.8 15.8 12.8 0.0 0.1 0.2 0.0 3.4 12.3 0.0 0.3 20.0 3.6 1.0 5.8 0.0 26.8 0.0 0.1 6.0 0.0 0.0 4.8 0.6 0.0 0.4 2.8 0.0 0.0 1.4 1.0 0.2 0.3 0.3 3.3 0.0 43.7 0.0 0.0 0.4 TNFSF4 "CD252, gp34, OX-40L, TXGP1" ENSG00000117586 "TNF superfamily member 4" P23510 1 173183731-173207331 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins" Cytokine "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 8.5;Granulosa cells: 37.0;Macrophages: 26.4;monocytes: 8.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 42.0;HHSteC: 17.3;HUVEC TERT2: 81.2;LHCN-M2: 67.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA059579 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Vesicles" "HPA059579: AB_2684071" "unprognostic (1.88e-2)" "unprognostic (1.20e-1)" "unprognostic (4.58e-2)" "unprognostic (2.74e-1)" "unprognostic (1.73e-2)" "unprognostic (1.74e-1)" "unprognostic (1.13e-3)" "unprognostic (2.13e-1)" "unprognostic (8.65e-2)" "unprognostic (5.17e-2)" "unprognostic (1.26e-2)" "unprognostic (1.18e-1)" "unprognostic (1.11e-7)" "unprognostic (3.73e-3)" "unprognostic (2.66e-1)" "unprognostic (9.49e-2)" "unprognostic (2.98e-2)" 1.2 2.0 1.1 2.3 1.2 0.6 0.6 1.8 1.5 1.0 0.1 1.0 0.3 0.8 0.5 0.6 0.9 1.1 1.0 1.1 0.9 0.8 0.9 1.2 2.2 1.2 1.2 1.1 1.1 0.5 1.5 0.5 1.2 1.4 1.2 1.4 0.4 0.6 0.2 0.3 0.8 0.8 0.8 1.7 0.7 4.0 1.1 3.7 0.4 0.2 1.9 1.5 0.8 1.2 0.1 0.0 0.4 1.2 2.7 14.1 0.2 4.1 0.9 0.2 0.3 0.2 0.1 0.2 0.7 42.0 0.2 0.1 0.1 0.1 0.3 0.7 0.1 0.1 0.4 1.6 17.3 0.3 0.2 6.2 0.3 2.1 0.3 1.3 81.2 1.5 0.1 0.5 67.5 0.0 0.7 0.4 0.3 0.1 0.6 2.0 0.1 0.6 0.6 0.1 0.1 0.6 0.3 0.2 0.9 1.3 0.0 0.7 0.6 0.1 0.1 0.4 0.2 0.9 1.4 0.3 0.2 7.7 4.4 0.0 0.1 0.1 0.5 0.0 0.3 0.5 0.2 0.4 0.3 0.5 0.4 0.4 0.7 1.7 0.0 1.2 0.4 2.8 1.1 1.2 1.8 1.5 1.1 0.9 1.2 1.2 1.2 0.8 1.1 1.2 0.2 0.0 0.5 8.5 0.8 0.8 0.3 0.4 0.6 0.4 0.2 0.0 1.5 1.5 0.1 1.8 0.0 0.2 2.2 0.9 0.0 0.1 5.8 0.2 0.4 1.0 0.0 0.8 3.6 0.0 0.2 3.7 0.0 0.1 0.0 37.0 0.0 1.2 0.5 0.0 5.2 0.0 0.0 0.6 2.3 2.2 0.3 26.4 1.8 0.0 8.2 1.3 2.1 2.5 4.0 0.3 0.1 1.9 0.4 0.4 0.0 0.2 0.8 0.5 0.0 0.6 3.7 0.3 0.2 0.0 0.6 0.0 2.4 0.7 0.1 0.1 TNK2 "ACK, ACK1, p21cdc42Hs" ENSG00000061938 "Tyrosine kinase non receptor 2" Q07912 3 195863364-195911945 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 102.9" "Cell type enhanced" "Detected in many" "Horizontal cells: 99.3;Oligodendrocyte precursor cells: 245.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041954, HPA069561" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" Vesicles "HPA041954: AB_10794164, HPA069561: " "unprognostic (1.97e-2)" "unprognostic (1.05e-1)" "unprognostic (1.15e-3)" "prognostic unfavorable (8.96e-4)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (8.89e-3)" "unprognostic (1.13e-1)" "unprognostic (8.92e-3)" "unprognostic (4.49e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (6.82e-2)" "unprognostic (9.76e-2)" "unprognostic (1.44e-1)" "prognostic favorable (1.00e-4)" 14.2 10.0 77.1 24.7 64.1 72.2 15.0 40.0 102.9 18.0 11.8 18.5 9.4 13.8 11.1 19.1 17.1 10.5 18.4 75.6 51.4 7.7 10.5 14.1 30.0 77.5 59.8 13.4 12.1 6.1 36.4 12.7 70.1 21.1 6.3 9.3 26.3 11.8 54.8 62.3 16.1 9.2 45.5 27.0 19.7 12.0 57.0 16.0 10.0 16.7 20.1 19.4 19.3 60.6 93.4 16.3 15.4 13.4 15.3 11.5 80.0 17.7 16.7 11.7 9.4 15.6 79.3 25.9 55.1 24.2 17.4 34.1 14.9 22.2 3.5 61.8 15.4 22.0 36.2 10.4 7.9 13.5 10.2 7.8 30.7 11.7 17.9 26.7 13.3 9.2 11.3 30.6 9.4 67.1 5.3 39.7 12.3 24.6 29.1 13.8 15.6 26.0 7.2 51.2 16.2 16.5 9.5 37.6 21.3 11.3 71.4 11.9 18.9 19.1 13.0 11.4 48.6 70.8 9.2 17.0 22.1 38.0 15.4 1.4 1.2 0.3 0.9 1.5 0.4 1.3 0.8 0.4 0.5 2.5 0.5 0.5 2.7 0.4 1.4 1.5 0.1 0.7 77.1 64.1 40.0 102.9 75.6 51.4 77.5 59.8 70.1 45.5 57.0 60.6 9.3 6.4 7.7 44.4 14.6 6.9 8.1 6.0 4.6 30.6 13.0 12.6 16.1 7.2 8.9 0.0 50.1 13.4 11.0 18.0 1.9 4.0 1.0 4.1 5.4 11.1 6.1 12.8 42.7 5.3 3.3 4.6 14.3 4.1 1.3 4.5 11.7 19.2 8.1 99.3 45.3 2.3 6.1 16.0 11.7 1.2 6.5 13.7 5.4 20.6 16.2 5.9 21.6 245.3 25.1 29.5 9.6 6.4 10.7 8.2 0.9 1.6 7.6 20.3 0.0 4.8 5.7 6.4 11.2 11.0 10.5 4.2 12.5 1.7 6.4 19.0 TNNC2 "CFAP85, FAP85" ENSG00000101470 "Troponin C2, fast skeletal type" P02585 20 45823214-45833745 "Predicted intracellular proteins" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 109 "skeletal muscle: 30416.4;tongue: 8088.6" "Group enriched" "Detected in many" 4 "Proximal enterocytes: 338.7;Skeletal myocytes: 1165.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 20.2;head and neck cancer: 22.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Hep G2: 10.0;HSkMC: 14.8;SCLC-21H: 11.3" "Region enriched" "Detected in some" 5 "olfactory bulb: 6.1" "Low region specificity" "Detected in some" "HPA043174, HPA058481" Enhanced Approved Nucleoplasm,Vesicles No NA 560000 "Cluster 19: B-cells - Humoral immune response" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm Vesicles "HPA043174: AB_10806380, HPA058481: AB_2683729" "unprognostic (1.13e-1)" "unprognostic (7.25e-2)" "unprognostic (3.43e-1)" "unprognostic (1.27e-1)" "unprognostic (3.21e-5)" "unprognostic (1.80e-2)" "unprognostic (5.72e-3)" "unprognostic (3.12e-3)" "unprognostic (2.19e-1)" "unprognostic (2.06e-1)" "unprognostic (2.38e-1)" "unprognostic (1.05e-1)" "unprognostic (9.03e-3)" "unprognostic (7.15e-3)" "unprognostic (4.79e-1)" "unprognostic (5.23e-2)" "unprognostic (1.13e-1)" 6.6 5.5 4.8 0.4 5.7 1.1 8.3 5.2 6.9 2.2 4.4 5.3 2.5 4.2 1.0 128.5 3.0 2.2 4.0 4.8 4.5 1.7 2.5 3.2 0.5 4.4 4.5 6.5 2.2 1.2 3.1 0.2 4.5 44.3 2.2 1.3 176.3 1.3 30416.4 10.1 7.8 1.0 4.1 1.8 2.4 4.6 4.8 6.7 5.1 8088.6 0.7 2.5 3.0 5.5 0.1 0.0 0.2 0.4 1.6 1.0 1.7 0.1 0.4 0.0 0.1 0.2 1.1 0.4 1.1 1.0 0.4 0.4 0.0 0.4 0.0 0.0 0.3 0.0 1.0 10.0 0.4 0.3 0.2 14.8 0.2 0.1 0.7 0.3 0.0 1.2 0.1 0.5 0.2 1.2 0.7 0.1 0.0 0.4 0.6 0.3 0.6 0.2 0.4 0.1 11.3 0.5 1.6 0.1 0.4 0.5 1.3 0.4 0.5 0.2 0.3 0.9 0.2 1.5 0.4 0.2 1.4 0.1 0.2 0.0 0.6 1.3 0.1 1.1 0.6 5.3 1.3 0.2 0.3 4.6 0.0 0.3 2.0 0.3 0.8 0.8 3.9 8.7 4.8 5.7 5.2 6.9 4.8 4.5 4.4 4.5 4.5 4.1 4.8 5.5 0.9 3.2 0.6 0.3 3.1 0.8 0.5 2.0 0.0 4.2 3.1 1.7 0.5 2.8 3.6 3.7 0.0 2.4 0.5 171.7 3.9 1.5 6.9 37.1 1.0 3.8 22.9 0.0 1.9 5.1 0.4 7.2 0.5 2.3 0.0 13.9 0.0 1.1 0.3 0.0 0.7 108.2 14.2 0.3 1.1 47.0 1.2 22.4 0.0 0.0 2.1 1.4 1.0 0.0 0.6 3.3 92.9 3.0 0.5 0.7 338.7 1.0 4.3 2.4 0.0 1165.3 9.5 2.5 5.5 0.1 8.4 0.1 4.7 7.2 37.0 0.7 TNNI3 "CMD2A, CMH7, TNNC1" ENSG00000129991 "Troponin I3, cardiac type" P19429 19 55151767-55157773 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 622 "heart muscle: 10813.5" "Cell type enriched" "Detected in many" 12 "Cardiomyocytes: 12618.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 13.0;HMC-1: 20.3;K-562: 39.1;OE19: 54.6" "Region enhanced" "Detected in many" "olfactory bulb: 10.9" "Low region specificity" "Detected in many" "CAB009349, HPA046428" Enhanced Approved Vesicles,Cytosol NA NA 2400000 "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 21: OE19 - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol Vesicles "CAB009349: AB_793465, HPA046428: AB_2679661" "unprognostic (2.12e-2)" "unprognostic (3.05e-2)" "unprognostic (2.44e-2)" "unprognostic (1.36e-1)" "unprognostic (2.08e-2)" "unprognostic (2.81e-2)" "unprognostic (1.37e-3)" "unprognostic (2.13e-1)" "unprognostic (9.62e-3)" "unprognostic (9.40e-2)" "unprognostic (3.34e-2)" "unprognostic (2.17e-3)" "unprognostic (4.02e-3)" "unprognostic (8.89e-2)" "unprognostic (8.54e-2)" "unprognostic (1.05e-1)" "unprognostic (9.82e-2)" 1.1 3.0 0.3 0.0 0.5 0.0 17.3 0.2 0.4 0.7 0.7 0.7 0.0 0.3 0.1 0.8 6.2 0.9 10813.5 0.6 0.2 1.0 1.1 7.3 1.6 0.5 2.8 1.4 2.3 0.2 0.6 1.0 1.3 2.4 0.0 0.2 1.3 0.0 6.5 1.2 0.6 0.0 0.6 0.4 0.7 3.7 0.3 0.1 1.5 2.4 0.0 0.4 0.6 0.3 1.2 0.6 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.4 0.0 0.3 1.8 6.3 0.0 1.1 1.1 1.2 0.3 0.0 0.0 13.0 3.0 0.0 1.9 0.5 0.0 20.3 0.0 0.6 0.1 0.3 0.1 0.1 0.8 39.1 0.8 0.0 0.6 0.2 0.0 0.7 54.6 0.5 1.9 0.4 0.1 1.8 0.0 0.1 2.2 0.0 0.0 0.2 0.0 2.8 9.5 0.4 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.6 3.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.2 0.4 0.6 0.2 0.5 2.8 1.3 0.6 0.3 0.3 0.1 0.0 0.0 0.0 0.2 6.9 0.0 0.8 13.6 0.0 1.0 0.9 12618.4 8.6 1.8 5.5 0.0 1.4 0.1 0.4 0.0 0.7 56.2 3.5 0.1 131.3 1.8 0.0 0.0 0.2 0.5 202.7 0.0 1.3 0.0 996.2 0.0 0.0 2.2 1.7 0.2 0.4 2.0 0.3 0.7 222.9 0.3 4.6 1.8 1.9 0.0 4.2 0.0 0.0 0.1 1.0 0.0 1.9 0.0 0.0 0.0 0.1 11.2 0.5 0.0 0.4 123.6 6.4 16.1 0.7 2.8 2.5 0.6 1.2 1.0 0.1 TNPO3 "IPO12, LGMD1F, MTR10A, TRN-SR, TRN-SR2" ENSG00000064419 "Transportin 3" Q9Y5L0 7 128954180-129055173 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039555, HPA041537" Approved Enhanced Vesicles NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA039555: AB_10672000, HPA041537: AB_2677539" "unprognostic (5.76e-2)" "unprognostic (1.72e-2)" "unprognostic (1.97e-1)" "unprognostic (5.49e-3)" "unprognostic (1.05e-1)" "unprognostic (1.74e-1)" "prognostic unfavorable (3.29e-5)" "unprognostic (1.86e-2)" "unprognostic (1.24e-1)" "unprognostic (1.93e-2)" "unprognostic (2.27e-2)" "unprognostic (2.34e-2)" "unprognostic (3.26e-2)" "unprognostic (4.70e-2)" "unprognostic (2.93e-1)" "unprognostic (2.04e-1)" "unprognostic (4.24e-2)" 16.1 16.9 17.1 19.3 17.7 34.3 15.7 19.0 18.7 14.1 16.3 18.4 16.4 15.6 17.8 21.1 16.2 13.0 15.6 17.3 19.9 19.1 22.9 16.0 23.4 17.0 17.6 20.5 15.1 21.1 10.0 14.8 19.3 16.6 20.1 16.5 15.5 18.0 32.6 18.1 16.6 19.5 17.2 17.7 19.7 26.4 19.0 30.1 22.8 27.0 28.8 18.6 15.1 17.6 59.1 65.3 49.7 84.3 47.3 40.5 42.3 51.8 45.0 47.4 55.5 53.7 52.9 73.3 23.6 55.7 89.7 42.3 101.6 49.8 67.6 61.3 45.0 54.0 52.2 42.2 45.0 99.8 44.2 38.1 49.7 57.9 51.4 41.4 59.9 59.5 124.7 51.3 61.2 43.7 86.9 73.4 142.6 64.4 59.7 61.0 46.3 60.0 48.0 54.6 61.5 48.7 55.2 25.7 58.3 71.4 29.0 61.3 45.2 59.7 29.4 71.1 71.5 65.3 54.6 99.3 86.3 100.5 106.1 26.7 14.1 22.0 16.4 17.3 14.6 16.1 13.3 14.8 16.1 15.5 13.0 15.2 15.5 14.5 23.9 7.7 15.1 11.7 17.1 17.7 19.0 18.7 17.3 19.9 17.0 17.6 19.3 17.2 19.0 17.6 20.4 16.0 16.7 30.7 31.4 6.8 15.6 5.7 27.3 23.4 20.3 13.8 21.4 20.0 11.6 18.4 22.9 24.7 26.9 20.4 7.9 23.2 41.4 19.1 17.7 18.8 11.5 38.5 45.8 24.8 37.2 17.4 22.4 27.7 10.8 30.5 19.6 27.9 27.8 37.0 46.8 22.2 2.0 25.7 9.5 25.4 16.8 24.9 8.8 31.9 44.4 13.6 17.5 37.7 47.5 30.3 17.7 17.7 28.5 17.6 21.7 18.7 13.1 21.7 13.1 18.5 19.4 76.3 31.8 32.5 8.2 35.0 23.5 33.1 24.8 30.4 TNRC6A "CAGH26, GW182, KIAA1460, TNRC6" ENSG00000090905 "Trinucleotide repeat containing adaptor 6A" Q8NDV7 16 24610209-24827632 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "RNA-mediated gene silencing, Translation regulation" RNA-binding Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 289.3;Excitatory neurons: 283.8;Inhibitory neurons: 414.6;Oligodendrocyte precursor cells: 265.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015305, HPA017869" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA015305: AB_1850454, HPA017869: AB_1850456" "unprognostic (2.64e-1)" "unprognostic (2.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.86e-1)" "unprognostic (5.00e-2)" "unprognostic (1.10e-3)" "unprognostic (1.62e-1)" "unprognostic (3.22e-3)" "unprognostic (5.49e-2)" "unprognostic (2.74e-1)" "unprognostic (7.44e-3)" "unprognostic (2.63e-3)" "unprognostic (1.78e-1)" "unprognostic (9.18e-2)" "unprognostic (5.77e-2)" "unprognostic (2.31e-1)" "unprognostic (3.35e-2)" 17.2 21.0 5.0 6.4 3.6 6.0 14.9 10.8 7.1 17.8 6.1 17.8 5.5 23.5 11.5 11.3 17.7 6.4 11.1 3.4 6.6 10.3 13.0 12.8 7.1 6.1 4.8 20.6 19.2 13.2 22.8 6.6 6.1 14.6 6.4 7.0 14.9 8.0 14.0 13.1 15.3 8.1 2.2 9.9 15.2 6.6 7.0 8.6 17.8 6.9 7.4 13.0 13.4 7.4 10.1 13.8 16.0 8.7 13.6 17.7 9.1 16.9 13.6 12.0 13.1 10.2 8.2 10.2 7.1 17.0 12.4 11.2 20.1 14.2 18.0 10.4 10.4 10.2 16.7 14.1 11.7 10.5 6.9 18.0 7.3 15.8 10.2 14.8 16.7 6.6 15.7 6.2 15.8 11.9 8.8 6.9 23.1 4.9 6.8 17.1 12.4 9.1 9.1 9.3 7.7 10.8 11.8 7.2 6.6 12.1 8.4 6.8 15.5 15.3 10.5 7.6 12.0 13.7 11.6 16.5 14.3 6.4 11.3 0.5 0.5 0.4 0.5 0.3 0.4 1.1 0.5 0.5 0.2 1.0 0.7 0.5 0.3 0.6 0.3 1.0 0.5 0.3 5.0 3.6 10.8 7.1 3.4 6.6 6.1 4.8 6.1 2.2 7.0 7.4 51.2 38.5 60.0 289.3 45.5 34.9 17.8 21.9 39.9 97.1 42.8 41.0 75.3 51.5 32.3 46.0 118.9 22.4 49.9 38.3 17.6 23.6 17.2 38.7 65.5 45.5 55.9 34.9 283.8 24.5 15.1 50.5 33.6 42.8 39.3 76.5 60.3 115.3 21.2 176.7 414.6 36.3 22.4 56.2 26.5 11.3 69.0 28.7 30.2 138.7 36.1 42.0 50.4 265.4 234.2 28.5 36.1 81.3 44.7 26.0 42.8 19.2 29.8 81.7 19.7 52.8 60.9 41.2 30.6 38.1 28.7 8.2 39.0 36.5 35.8 17.4 TOB1 "APRO5, TOB, TROB, TROB1" ENSG00000141232 "Transducer of ERBB2, 1" P50616 17 50862223-50867978 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "T-47d: 253.3" "Low region specificity" "Detected in all" HPA047839 Approved Approved Nucleoplasm,Vesicles NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm Vesicles "HPA047839: AB_2680175" "unprognostic (3.46e-1)" "unprognostic (1.09e-1)" "unprognostic (2.45e-1)" "unprognostic (6.78e-3)" "unprognostic (1.19e-1)" "unprognostic (8.27e-2)" "unprognostic (3.50e-3)" "unprognostic (1.53e-1)" "unprognostic (3.56e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (5.04e-5)" "prognostic unfavorable (3.37e-4)" "unprognostic (3.92e-3)" "unprognostic (9.44e-2)" "unprognostic (1.09e-1)" "unprognostic (4.13e-2)" "unprognostic (6.97e-2)" 42.6 210.2 32.6 22.3 34.9 70.2 65.3 31.6 40.8 55.3 59.3 47.4 56.1 23.9 26.5 77.7 54.6 47.6 44.7 29.8 39.4 67.9 168.6 36.8 18.9 37.3 48.2 63.4 207.9 81.4 50.1 13.8 38.6 72.3 57.5 101.8 99.8 92.2 178.6 133.5 48.1 29.4 31.8 17.8 87.5 26.0 33.4 17.7 95.4 109.9 21.0 81.9 70.9 40.2 44.1 88.7 28.1 11.5 51.4 25.4 22.0 31.9 79.2 20.5 25.0 36.0 54.6 40.0 60.6 43.9 20.7 61.0 19.5 54.1 21.1 20.4 29.3 4.8 100.7 60.5 72.0 21.5 18.9 54.5 65.5 23.9 120.0 27.3 9.9 12.2 17.0 33.7 43.4 119.0 16.1 19.4 10.2 109.4 33.9 14.0 35.6 47.6 80.9 89.4 16.6 40.4 55.1 158.9 19.9 42.5 253.3 27.1 13.2 23.3 16.7 26.7 15.8 51.9 57.7 18.5 19.2 10.2 9.1 417.7 53.5 285.6 245.8 107.3 269.9 40.7 222.7 192.5 119.1 31.9 192.1 233.6 130.7 28.8 152.5 38.5 206.0 169.0 32.6 34.9 31.6 40.8 29.8 39.4 37.3 48.2 38.6 31.8 33.4 40.2 101.6 115.4 118.3 71.8 53.1 283.2 232.9 119.8 284.0 125.3 180.6 179.6 115.5 210.1 81.8 68.0 56.3 20.8 124.8 183.3 103.7 42.6 97.9 143.7 51.7 40.7 203.4 18.1 11.5 54.1 2.0 83.5 123.3 176.2 63.9 19.7 33.2 205.6 35.4 18.5 14.1 223.2 48.8 27.6 249.2 40.4 26.4 89.9 71.2 5.6 29.1 118.3 20.6 16.6 34.1 41.8 186.7 59.8 41.3 187.2 126.2 60.4 87.8 62.7 164.3 137.3 123.8 36.9 12.1 153.8 230.7 10.9 154.7 77.4 167.6 287.2 TOMM34 "HTOM34P, TOM34" ENSG00000025772 "Translocase of outer mitochondrial membrane 34" Q15785 20 44942130-44960397 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 119.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 128.3;monocytes: 176.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018845, HPA056875" Enhanced Supported Vesicles,Mitochondria,Cytosol NA NA 26000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 78: Testis - Spermatogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 47: Cytotrophoblasts - Unknown function" Cytosol "Vesicles, Mitochondria" "HPA018845: AB_1858184, HPA056875: AB_2683264" "unprognostic (4.96e-2)" "unprognostic (6.88e-2)" "unprognostic (5.05e-2)" "unprognostic (1.36e-3)" "unprognostic (4.91e-2)" "prognostic unfavorable (4.47e-5)" "prognostic unfavorable (8.71e-6)" "unprognostic (2.55e-1)" "unprognostic (5.04e-2)" "unprognostic (1.05e-1)" "unprognostic (1.52e-2)" "unprognostic (2.11e-2)" "unprognostic (1.55e-2)" "unprognostic (3.04e-1)" "unprognostic (1.02e-1)" "prognostic favorable (5.45e-4)" "unprognostic (5.79e-3)" 13.4 46.0 31.4 13.6 40.3 20.1 14.6 24.3 51.7 14.5 28.3 14.6 11.8 14.8 49.0 19.5 49.1 13.6 16.0 54.6 32.6 28.6 18.8 14.0 15.2 29.0 26.1 26.4 18.0 24.4 26.6 29.6 28.0 18.8 18.4 9.0 15.7 16.9 18.0 14.6 13.7 15.4 24.7 14.9 15.8 119.4 33.6 18.3 16.5 15.2 22.0 26.2 12.7 35.7 133.6 46.0 40.1 85.6 36.3 35.6 90.2 75.6 109.6 92.8 67.1 187.4 48.6 90.9 63.5 59.6 94.2 82.1 98.8 164.0 107.3 16.1 46.2 71.7 58.2 133.7 46.2 47.5 42.3 38.7 45.2 129.8 230.8 80.9 95.8 36.6 82.6 36.4 89.3 88.2 50.2 65.4 47.1 70.7 172.8 43.1 42.2 98.9 76.1 73.7 68.3 40.4 103.5 71.0 91.8 30.7 53.5 40.8 57.2 121.5 80.0 58.9 114.8 31.2 40.1 75.4 110.9 55.8 48.2 15.9 16.9 15.3 14.8 17.5 15.4 25.4 15.3 15.7 39.7 28.6 17.1 13.7 4.6 14.8 18.8 21.1 19.3 17.3 31.4 40.3 24.3 51.7 54.6 32.6 29.0 26.1 28.0 24.7 33.6 35.7 7.3 6.4 11.5 3.6 15.0 13.8 84.6 17.2 14.8 3.1 14.1 11.2 10.3 5.7 15.5 12.9 4.2 128.3 8.7 7.7 31.3 38.4 18.5 17.5 7.2 13.0 12.0 17.2 6.8 30.7 38.0 14.8 16.8 14.8 9.5 28.2 6.4 9.1 22.7 3.3 4.8 9.3 8.2 5.9 47.2 32.9 6.8 10.3 7.2 5.6 176.9 17.4 7.2 3.5 2.7 46.2 9.5 6.4 16.9 69.1 6.9 22.5 44.3 4.2 0.0 5.6 13.6 43.0 56.2 15.7 11.1 56.5 8.8 24.0 13.6 55.9 TOR1A "DQ2, DYT1" ENSG00000136827 "Torsin family 1 member A" O14656 9 129812942-129824244 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Chaperone, Hydrolase" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012473, HPA051195" Approved Supported "Nuclear membrane,Vesicles" "Intracellular and membrane" NA NA 20000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Nuclear membrane, Vesicles" "CAB012473: AB_2240792, HPA051195: AB_2681382" "unprognostic (1.20e-1)" "unprognostic (1.92e-1)" "unprognostic (2.65e-1)" "unprognostic (1.18e-1)" "unprognostic (1.95e-1)" "unprognostic (1.86e-3)" "unprognostic (3.67e-2)" "prognostic unfavorable (5.45e-4)" "unprognostic (2.10e-2)" "unprognostic (1.41e-1)" "unprognostic (4.10e-2)" "unprognostic (2.86e-1)" "unprognostic (1.35e-1)" "unprognostic (3.39e-1)" "unprognostic (1.91e-1)" "unprognostic (1.77e-1)" "unprognostic (1.99e-1)" 21.2 24.2 14.3 20.7 14.8 34.5 19.6 14.7 17.7 18.6 14.2 20.7 16.6 20.3 19.9 14.3 17.2 20.6 16.8 15.7 15.9 20.5 35.9 19.4 22.9 13.6 14.0 17.2 19.5 19.4 14.3 23.5 14.0 21.3 22.3 9.8 17.0 23.1 16.4 17.8 18.8 25.4 14.1 18.8 18.1 9.2 15.4 26.3 23.8 14.9 19.0 28.6 15.6 14.8 33.7 49.5 35.9 41.5 53.1 51.3 47.4 76.7 94.5 67.0 57.2 32.3 48.2 41.0 44.0 99.7 46.0 77.2 34.7 50.8 54.7 65.7 32.9 36.9 49.8 32.3 66.9 82.1 65.5 69.8 50.7 63.5 45.6 61.5 73.2 65.3 66.5 32.3 74.6 84.3 58.9 79.3 53.8 39.2 55.6 30.5 56.5 41.9 54.9 42.4 27.0 47.6 79.3 30.7 43.3 40.1 61.6 63.4 65.1 66.1 37.7 49.6 59.6 36.6 87.0 37.7 49.0 46.9 54.3 95.5 72.8 141.3 57.4 68.5 48.1 45.5 48.4 52.1 61.4 33.5 40.9 42.4 72.7 68.6 58.3 56.5 59.1 78.9 14.3 14.8 14.7 17.7 15.7 15.9 13.6 14.0 14.0 14.1 15.4 14.8 25.0 9.6 11.8 5.5 17.5 17.6 16.6 39.5 12.0 11.2 16.5 15.9 9.9 18.6 24.4 14.7 2.1 47.9 39.3 18.7 15.6 42.1 0.7 12.5 18.8 24.2 19.2 30.5 6.3 49.9 65.7 25.0 13.7 15.0 22.2 23.4 16.1 22.7 45.2 21.9 6.4 17.8 26.4 19.1 22.4 1.3 12.8 27.9 14.2 3.7 47.6 18.5 35.0 9.5 6.6 40.1 18.9 15.4 23.7 24.7 21.0 17.0 14.9 9.2 32.9 15.2 24.3 7.3 10.1 9.3 18.5 53.4 25.5 23.4 15.4 19.6 TOX4 "C14orf92, KIAA0737, LCP1" ENSG00000092203 "TOX high mobility group box family member 4" O94842 14 21476597-21499175 "Plasma proteins, Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 265.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017880, HPA027551" Approved Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Nucleoli, Vesicles" "HPA017880: AB_1845573, HPA027551: AB_10601701" "unprognostic (9.56e-2)" "unprognostic (2.54e-2)" "unprognostic (2.81e-1)" "unprognostic (7.46e-2)" "unprognostic (9.30e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (3.46e-4)" "unprognostic (8.05e-3)" "unprognostic (2.58e-1)" "unprognostic (5.00e-2)" "unprognostic (3.23e-2)" "unprognostic (2.94e-1)" "prognostic favorable (8.38e-5)" "unprognostic (1.84e-1)" "unprognostic (2.48e-1)" "unprognostic (9.03e-2)" "unprognostic (2.48e-3)" 16.7 14.6 17.3 14.1 17.6 21.4 16.3 17.9 20.1 18.0 14.8 18.5 12.6 15.4 15.1 21.1 14.7 12.2 21.9 17.5 17.7 15.0 15.7 15.9 15.1 17.1 18.7 15.9 15.8 20.4 13.6 15.5 17.5 14.7 15.2 16.1 14.8 17.4 55.5 21.5 14.8 19.7 16.8 13.7 16.9 14.3 18.3 26.1 17.1 25.8 21.3 17.4 16.0 19.5 27.1 27.4 22.7 21.5 32.1 30.6 30.3 25.3 49.6 52.7 50.3 27.0 31.6 16.2 17.5 41.5 42.0 31.5 37.4 38.8 66.8 28.6 15.1 18.1 17.7 37.8 41.5 33.6 28.7 40.0 39.8 41.7 39.4 35.9 38.0 30.1 22.6 27.4 37.9 22.8 33.4 19.3 12.8 39.5 43.2 29.7 23.7 18.6 24.5 33.4 20.9 21.5 25.0 26.3 21.3 29.8 24.8 12.6 25.0 27.2 24.9 24.1 22.5 35.1 41.7 36.9 12.8 16.4 28.7 40.9 27.4 40.0 23.1 29.2 25.0 24.0 20.5 22.2 26.0 24.9 21.3 24.4 48.6 29.2 27.5 33.7 31.7 28.9 17.3 17.6 17.9 20.1 17.5 17.7 17.1 18.7 17.5 16.8 18.3 19.5 60.0 67.3 64.0 0.0 43.3 87.3 63.9 81.3 58.1 75.0 50.4 42.0 51.8 42.9 64.4 46.0 29.2 73.5 69.3 51.0 62.6 47.3 76.1 42.6 46.9 53.4 68.9 48.8 0.0 51.4 64.1 48.4 40.8 50.4 61.4 41.4 37.9 43.1 43.8 42.1 0.0 45.4 52.9 41.3 61.6 36.5 48.7 46.1 39.2 0.0 55.3 40.4 46.4 0.0 0.0 51.4 51.9 44.0 44.4 59.0 91.4 64.0 57.4 54.5 32.9 54.1 58.6 131.9 66.8 50.5 88.8 265.8 62.0 55.5 43.8 70.0 TP53BP1 "53BP1, p202, TDRD30" ENSG00000067369 "Tumor protein p53 binding protein 1" Q12888 15 43403061-43510728 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004083, HPA008788, HPA022133, CAB079980" Supported Supported "Nucleoplasm,Nuclear bodies,Mitotic chromosome,Vesicles" Yes No "Cluster 46: Basophils - DNA binding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Nuclear bodies" "Nucleoplasm, Mitotic chromosome, Vesicles" "CAB004083: AB_10694558, CAB079980: , HPA008788: AB_1078070, HPA022133: AB_1844382" "unprognostic (2.12e-1)" "unprognostic (7.96e-2)" "unprognostic (1.11e-1)" "unprognostic (1.85e-2)" "unprognostic (4.42e-3)" "unprognostic (2.32e-1)" "unprognostic (2.03e-2)" "unprognostic (3.96e-1)" "unprognostic (2.17e-1)" "unprognostic (2.81e-2)" "unprognostic (3.34e-2)" "unprognostic (4.07e-1)" "unprognostic (8.06e-2)" "unprognostic (9.11e-2)" "unprognostic (1.52e-1)" "unprognostic (6.99e-2)" "unprognostic (3.38e-2)" 6.9 11.5 17.4 10.1 16.6 11.5 10.7 19.9 14.5 17.7 21.5 9.7 6.4 16.0 15.9 6.1 14.7 10.7 8.8 15.4 26.3 9.1 4.1 8.3 8.6 13.5 16.7 16.8 7.4 22.3 24.1 12.2 15.7 12.1 10.2 22.0 10.1 12.8 7.2 9.2 6.4 16.3 9.6 8.7 7.6 21.6 23.0 15.3 17.9 11.0 12.6 11.2 8.7 12.1 13.5 22.3 63.8 40.1 25.8 31.9 15.8 22.8 33.8 31.0 39.1 19.4 15.8 14.5 19.2 39.0 66.9 32.4 46.3 27.5 36.8 38.9 15.8 27.1 40.1 11.7 16.8 30.2 37.4 24.9 19.0 41.8 31.2 51.7 37.4 24.2 26.9 12.3 36.5 9.6 23.7 14.1 41.1 24.2 13.9 25.1 23.9 9.3 22.9 31.8 57.3 26.8 33.8 14.3 8.5 48.6 29.9 16.9 27.5 33.7 22.3 27.0 20.5 9.8 22.4 33.0 27.6 14.6 17.5 1.4 0.5 1.0 1.6 0.7 1.3 1.9 1.6 1.6 1.2 1.8 1.8 1.6 0.6 0.9 0.5 1.3 1.4 0.7 17.4 16.6 19.9 14.5 15.4 26.3 13.5 16.7 15.7 9.6 23.0 12.1 11.5 22.4 22.3 53.2 17.8 6.4 10.2 10.0 13.6 32.4 17.4 13.2 14.9 5.7 20.8 29.5 47.9 13.4 11.1 7.4 9.8 14.5 38.8 47.0 44.8 16.8 41.9 8.4 66.2 7.1 11.2 23.9 14.8 26.8 26.6 47.0 15.0 3.3 10.8 47.1 81.9 15.7 12.2 3.8 6.9 17.8 23.6 9.3 1.8 17.8 4.0 11.9 7.2 62.8 50.4 7.5 5.8 17.7 17.1 11.0 2.6 8.8 60.7 51.7 13.1 35.2 20.5 33.1 36.2 14.7 5.3 18.5 17.0 29.9 13.4 8.9 TP53I3 PIG3 ENSG00000115129 "Tumor protein p53 inducible protein 3" Q53FA7 2 24077433-24085861 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 119.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 175.8;Late spermatids: 213.9;Proximal enterocytes: 200.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 6 "T-47d: 599.7" "Low region specificity" "Detected in all" "CAB017479, HPA022012, HPA028742" Enhanced Supported Vesicles NA NA 250000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "CAB017479: AB_2303667, HPA022012: AB_1858202, HPA028742: AB_10603456" "unprognostic (3.66e-2)" "unprognostic (1.41e-3)" "unprognostic (5.55e-2)" "unprognostic (8.04e-2)" "unprognostic (7.10e-3)" "unprognostic (4.47e-1)" "unprognostic (1.09e-2)" "unprognostic (1.53e-3)" "unprognostic (1.17e-1)" "unprognostic (2.83e-2)" "unprognostic (3.52e-2)" "unprognostic (1.75e-1)" "unprognostic (9.89e-2)" "unprognostic (1.40e-1)" "unprognostic (2.86e-1)" "unprognostic (3.67e-2)" "unprognostic (8.57e-3)" 20.2 24.6 8.6 16.1 9.8 20.0 17.2 8.4 9.6 29.6 11.2 54.4 51.5 17.3 4.5 119.2 16.5 26.3 15.4 7.5 9.0 46.8 15.2 29.9 7.2 9.4 11.1 8.2 40.1 7.0 11.7 10.6 8.5 15.0 40.8 2.0 25.3 11.2 6.2 8.0 69.1 16.9 7.7 11.9 25.3 38.4 13.0 14.2 23.6 5.9 10.1 22.3 63.8 9.7 27.5 86.8 50.6 21.1 38.8 85.3 37.2 27.3 32.3 22.6 31.1 22.1 48.4 3.5 15.0 44.0 6.1 8.0 13.1 46.5 13.8 21.6 2.0 8.7 33.3 57.5 25.2 4.1 15.3 92.3 72.3 60.2 14.7 46.1 102.0 16.3 7.3 23.4 95.5 18.1 5.0 0.6 39.2 30.8 36.0 10.1 45.7 0.9 38.1 41.4 7.2 32.9 35.1 7.8 6.1 40.5 599.7 5.6 80.6 26.9 63.8 18.5 13.7 10.6 7.4 3.0 8.9 0.4 7.0 11.8 19.1 16.9 0.2 12.6 0.2 4.9 0.2 0.6 16.0 5.5 0.1 0.4 4.1 0.3 5.6 7.1 0.5 6.1 8.6 9.8 8.4 9.6 7.5 9.0 9.4 11.1 8.5 7.7 13.0 9.7 19.2 28.9 38.4 3.9 6.8 4.7 24.7 69.7 6.8 0.8 25.8 33.0 9.0 50.1 51.9 42.3 0.0 41.9 1.1 175.8 109.5 93.5 127.8 50.4 47.4 20.3 79.4 7.2 0.4 134.7 31.9 30.6 83.6 68.2 12.7 85.8 23.9 12.9 45.0 0.0 0.4 63.9 57.0 22.9 11.1 213.9 7.8 20.9 14.2 4.7 23.9 9.5 0.0 5.0 0.3 91.1 138.5 9.1 8.0 11.4 200.9 104.7 19.2 1.9 19.7 14.1 36.8 56.6 14.3 38.8 7.0 28.9 3.4 16.2 75.2 49.9 TPD52L2 "D54, hD54, TPD54" ENSG00000101150 "TPD52 like 2" O43399 20 63865228-63891545 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 187.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047489 Approved Approved Vesicles,Cytosol NA NA 1100000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Vesicles Cytosol "HPA047489: AB_2680067" "unprognostic (1.17e-2)" "unprognostic (2.43e-1)" "unprognostic (3.25e-2)" "unprognostic (1.11e-2)" "unprognostic (9.31e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (1.39e-5)" "unprognostic (3.63e-3)" "unprognostic (9.95e-2)" "unprognostic (1.17e-2)" "unprognostic (1.47e-1)" "unprognostic (5.69e-2)" "prognostic unfavorable (1.74e-8)" "unprognostic (2.79e-1)" "unprognostic (7.07e-2)" "unprognostic (3.33e-2)" "unprognostic (3.15e-3)" 85.1 84.6 75.8 52.8 76.8 98.9 68.9 76.0 88.1 74.1 74.0 79.7 38.3 72.6 31.4 109.6 68.0 42.6 85.7 76.8 81.6 66.2 51.4 60.8 43.2 80.8 77.4 60.7 45.5 38.3 58.9 65.9 79.5 66.3 35.2 24.6 50.3 60.9 70.2 70.8 52.6 72.1 78.0 71.4 54.5 40.2 83.5 35.7 49.8 53.4 41.7 83.6 71.5 81.4 175.2 87.9 54.5 66.9 122.4 193.8 80.4 196.7 173.0 343.1 145.0 326.9 194.9 70.0 211.3 200.0 204.2 168.4 111.5 269.0 198.7 39.5 46.4 66.9 112.6 199.6 129.9 85.0 66.3 140.3 296.6 138.5 221.3 121.6 160.1 74.0 140.4 101.0 137.0 96.3 83.5 109.4 78.7 172.6 308.1 114.0 59.5 113.3 135.8 76.0 82.3 92.2 230.9 177.5 165.3 80.3 120.6 171.5 170.1 273.4 79.1 160.9 145.4 63.2 108.6 85.0 256.8 79.0 86.6 66.9 73.0 47.1 29.4 55.1 36.8 33.5 32.3 34.2 47.6 31.4 32.4 29.8 137.3 47.5 48.1 24.0 38.8 74.6 75.8 76.8 76.0 88.1 76.8 81.6 80.8 77.4 79.5 78.0 83.5 81.4 37.5 16.0 23.4 36.2 26.6 44.1 28.3 58.8 33.0 18.9 28.0 31.1 45.4 20.0 31.3 22.0 6.2 77.2 28.6 27.8 39.2 50.5 7.8 21.7 38.4 36.7 18.6 26.9 19.6 32.1 104.0 37.7 23.9 31.9 38.7 25.8 28.9 14.5 187.3 8.4 21.7 27.2 20.3 47.4 33.0 12.1 42.0 52.3 28.4 7.5 50.6 32.5 27.8 13.6 32.3 74.8 25.1 65.1 29.4 51.7 37.5 36.6 26.5 19.7 46.0 18.9 65.6 13.9 25.6 37.2 42.3 108.8 25.0 42.3 27.9 44.4 TPI1 ENSG00000111669 "Triosephosphate isomerase 1" P60174 12 6867119-6870948 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Glycolysis" "Isomerase, Lyase" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2470.8;tongue: 2005.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050924, HPA053568" Uncertain Approved Nucleoplasm,Vesicles NA NA 170000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm Vesicles "HPA050924: AB_2681276, HPA053568: AB_2682193" "unprognostic (2.85e-1)" "unprognostic (5.58e-3)" "unprognostic (1.65e-1)" "unprognostic (1.62e-2)" "unprognostic (6.94e-2)" "unprognostic (2.31e-2)" "prognostic unfavorable (1.04e-5)" "unprognostic (4.14e-3)" "unprognostic (7.49e-2)" "unprognostic (2.13e-2)" "unprognostic (2.11e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (6.54e-4)" "unprognostic (7.04e-2)" "unprognostic (1.82e-1)" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" 340.4 588.6 446.2 269.7 480.2 334.8 274.5 476.5 541.9 314.1 446.9 425.6 421.0 240.5 220.2 764.4 248.2 216.8 819.8 481.0 462.0 609.0 536.1 308.6 253.9 459.2 460.4 269.9 238.1 496.4 236.8 287.2 467.2 272.1 435.3 625.0 377.6 273.3 2470.8 410.1 404.5 301.5 429.7 291.4 329.0 239.8 503.5 200.3 269.1 2005.8 410.4 363.8 440.6 454.4 1556.8 1350.5 706.1 1094.6 666.5 696.6 1236.3 1097.5 1184.9 1999.1 2407.5 1409.9 823.0 903.4 212.7 1069.7 1042.4 748.8 1671.0 1812.3 2189.4 1196.4 1265.1 1172.0 924.4 926.2 496.8 1351.5 924.0 764.0 739.7 1537.8 1305.0 2816.1 1233.3 451.0 615.0 336.5 1554.5 1130.0 709.6 1119.5 1741.0 1302.3 855.9 413.5 1156.1 930.7 1261.4 1061.1 497.2 830.0 953.3 977.8 542.7 1452.6 224.4 1003.2 778.2 1068.0 914.6 703.1 1631.7 653.4 285.7 1327.8 2153.1 821.2 784.9 1708.8 2304.1 2375.2 824.6 2402.3 845.7 863.3 820.0 808.0 2656.1 800.9 570.5 703.0 934.3 1387.7 2165.7 482.0 1106.3 4679.5 446.2 480.2 476.5 541.9 481.0 462.0 459.2 460.4 467.2 429.7 503.5 454.4 311.5 134.6 204.2 34.6 290.6 684.8 553.8 1756.4 414.9 284.6 294.3 303.3 552.5 391.7 673.0 389.9 110.5 1017.0 278.2 850.3 1508.5 1361.5 203.0 280.8 307.0 352.0 425.5 243.3 38.4 786.5 1824.0 386.5 408.3 343.9 362.8 364.8 276.6 547.3 937.3 297.8 33.7 567.2 1151.5 386.7 750.4 683.5 279.0 482.8 674.1 18.7 1129.8 739.6 312.0 17.1 26.7 1081.5 889.4 263.3 427.9 556.2 1595.9 1642.7 401.2 298.0 197.2 270.5 551.3 14.9 79.0 690.4 615.9 1530.4 352.9 869.2 827.0 652.5 TPK1 "HTPK1, PP20" ENSG00000196511 "Thiamin pyrophosphokinase 1" Q9H3S4 7 144451941-144836395 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 14.3" "Cell type enhanced" "Detected in many" "Early spermatids: 83.0;Excitatory neurons: 82.6;Inhibitory neurons: 76.3;Late spermatids: 95.8;Microglial cells: 110.5" "Cancer enhanced" "Detected in many" "renal cancer: 3.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 70.6;CACO-2: 17.2;EFO-21: 21.2;TIME: 16.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021545, HPA021849" Approved Approved Vesicles NA NA 210000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA021545: AB_1858209, HPA021849: AB_1858210" "unprognostic (4.05e-2)" "unprognostic (3.28e-2)" "unprognostic (2.38e-2)" "unprognostic (3.32e-2)" "unprognostic (2.42e-1)" "unprognostic (1.63e-1)" "unprognostic (7.62e-2)" "unprognostic (6.08e-2)" "unprognostic (2.37e-1)" "unprognostic (1.68e-1)" "unprognostic (3.76e-2)" "unprognostic (6.06e-2)" "unprognostic (1.45e-3)" "unprognostic (3.15e-1)" "unprognostic (2.87e-1)" "unprognostic (1.59e-1)" "unprognostic (9.22e-3)" 4.3 3.4 2.9 5.9 3.2 2.7 4.2 2.1 4.1 2.7 3.3 6.4 14.3 2.2 1.5 1.9 2.0 3.6 3.4 2.8 5.2 3.9 4.5 5.2 5.8 3.1 3.0 2.3 2.0 1.8 1.5 5.2 3.0 1.8 6.1 2.4 3.6 2.6 1.6 1.4 7.5 3.6 2.9 8.1 2.2 3.4 4.3 2.8 3.1 2.9 5.0 4.1 1.6 3.9 0.7 0.7 0.7 70.6 0.5 0.7 5.8 0.3 0.3 0.2 0.2 17.2 2.8 1.3 21.2 1.2 1.4 0.0 1.4 0.8 0.6 4.3 1.0 0.3 0.2 0.3 1.8 5.5 1.7 1.4 1.4 0.8 1.0 2.0 13.6 2.8 1.5 3.2 0.3 2.1 1.6 8.2 1.8 2.1 5.9 0.7 1.6 2.5 10.9 6.3 0.7 0.2 1.1 0.2 1.3 1.3 1.0 10.4 16.3 0.7 1.8 1.3 0.9 1.6 4.2 1.7 2.5 13.8 0.7 0.4 10.2 0.3 5.0 7.4 5.2 6.7 5.5 4.6 13.2 7.2 6.5 5.4 4.7 5.8 10.8 3.1 7.7 5.6 2.9 3.2 2.1 4.1 2.8 5.2 3.1 3.0 3.0 2.9 4.3 3.9 8.5 9.6 2.8 43.1 23.8 2.3 2.6 3.0 0.6 3.9 4.4 2.9 5.9 8.6 1.3 3.7 8.4 41.2 8.3 20.1 19.6 4.3 83.0 5.3 2.3 8.9 1.2 2.1 82.6 6.7 14.3 6.3 7.1 8.6 7.6 6.5 6.1 5.2 17.0 1.7 76.3 5.0 0.0 18.9 19.2 95.8 5.0 17.9 8.8 110.5 15.7 3.4 17.5 55.8 38.4 9.8 15.9 1.2 9.9 1.8 20.4 8.6 3.2 5.4 0.0 3.6 2.9 14.9 10.5 2.1 1.7 32.0 12.1 4.0 8.1 4.1 TPRA1 "FLJ32197, GPR175, TMEM227, TPRA40" ENSG00000163870 "Transmembrane protein adipocyte associated 1" Q86W33 3 127571232-127598267 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 179.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019784 Approved Approved Vesicles NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 31: Skin - Epidermis development" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" Vesicles "HPA019784: AB_2670266" "unprognostic (1.52e-1)" "unprognostic (1.33e-2)" "unprognostic (9.41e-3)" "unprognostic (1.66e-2)" "unprognostic (6.91e-3)" "unprognostic (9.74e-2)" "prognostic unfavorable (6.46e-4)" "unprognostic (3.46e-1)" "unprognostic (2.32e-1)" "unprognostic (1.91e-1)" "unprognostic (1.17e-1)" "unprognostic (1.11e-1)" "unprognostic (2.02e-2)" "unprognostic (1.73e-2)" "unprognostic (4.42e-2)" "unprognostic (2.09e-1)" "unprognostic (4.28e-2)" 23.9 29.7 22.4 11.7 23.3 26.5 24.5 23.4 26.2 35.8 25.9 25.8 16.9 28.8 12.5 26.4 28.1 16.5 24.7 22.3 23.3 26.8 37.0 24.9 13.9 22.9 23.4 27.8 26.7 29.0 21.7 20.8 23.0 28.8 11.3 8.0 26.4 16.2 26.8 42.9 21.2 17.2 22.7 25.0 25.8 16.3 24.2 11.5 27.0 19.8 13.0 28.5 28.8 22.7 40.0 31.2 12.9 27.3 51.4 28.6 42.1 20.5 34.2 24.7 22.2 22.1 30.9 36.7 37.6 38.4 77.2 43.6 22.6 34.8 12.9 20.0 15.0 21.4 46.0 20.7 56.6 13.3 44.7 28.8 28.8 16.4 42.8 51.2 18.0 24.5 14.0 36.7 30.4 39.8 18.5 43.4 19.3 25.5 23.4 31.9 17.0 37.0 29.6 19.1 24.6 9.5 37.7 57.7 35.1 10.4 27.3 42.3 28.7 29.6 13.1 60.0 13.2 25.0 21.0 34.4 31.9 38.8 22.4 3.8 12.9 11.5 6.4 9.4 8.6 6.6 7.4 9.5 12.7 6.4 5.6 6.8 7.0 6.6 8.4 9.7 7.2 6.5 22.4 23.3 23.4 26.2 22.3 23.3 22.9 23.4 23.0 22.7 24.2 22.7 15.7 22.4 7.0 13.1 11.7 50.0 20.5 18.8 24.5 7.8 16.3 17.9 11.8 11.5 16.5 25.8 4.2 56.9 8.4 18.2 5.9 29.1 2.7 23.5 18.0 22.8 17.4 46.5 9.3 19.6 43.3 22.9 17.9 27.5 17.8 13.9 21.8 21.7 32.9 5.0 9.7 18.7 18.3 16.0 179.7 2.4 33.5 32.0 30.2 5.6 52.3 11.2 20.6 6.6 8.1 31.4 17.6 19.5 17.9 37.5 37.5 13.1 12.4 8.9 13.1 13.2 18.3 8.4 17.9 19.1 54.4 68.1 12.6 12.7 20.7 23.5 TPRG1L "FAM79A, FLJ21811, RP11-46F15.3" ENSG00000158109 "Tumor protein p63 regulated 1 like" Q5T0D9 1 3625015-3630127 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Horizontal cells: 126.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063163, CAB079051" Supported Approved Vesicles,Cytosol NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 62: Horizontal cells - Visual perception" "Vesicles, Cytosol" "CAB079051: , HPA063163: AB_2684953" "unprognostic (1.92e-1)" "unprognostic (3.26e-3)" "unprognostic (4.46e-2)" "unprognostic (7.99e-2)" "unprognostic (4.50e-2)" "unprognostic (3.35e-1)" "unprognostic (1.46e-1)" "unprognostic (1.34e-1)" "unprognostic (1.77e-1)" "unprognostic (5.37e-2)" "unprognostic (1.50e-1)" "unprognostic (7.83e-3)" "prognostic favorable (1.76e-9)" "unprognostic (1.53e-1)" "unprognostic (2.01e-1)" "unprognostic (1.57e-1)" "unprognostic (1.60e-1)" 45.7 37.3 80.3 21.4 84.6 35.4 36.5 58.7 92.7 39.5 56.9 49.4 50.1 36.5 40.7 56.8 48.1 37.7 52.5 87.7 81.1 65.6 85.5 34.4 27.4 80.3 74.7 49.0 38.1 38.4 47.0 24.0 83.9 33.3 46.4 49.8 39.9 47.0 67.6 54.7 54.4 35.7 62.9 30.2 40.5 18.7 80.3 25.0 43.5 70.0 38.5 41.7 39.8 76.9 31.3 22.0 13.3 23.9 98.1 67.8 12.2 45.4 62.4 41.3 27.2 41.5 27.9 11.5 39.6 62.5 22.2 48.1 16.1 42.0 34.7 36.7 25.7 16.0 24.4 48.4 59.4 23.6 18.3 51.3 60.7 34.2 34.7 50.2 59.0 19.7 11.6 39.8 58.3 14.3 17.1 24.2 17.9 71.5 50.9 14.2 19.8 27.8 42.5 32.3 37.1 36.6 24.3 49.8 50.6 30.2 31.2 20.3 67.7 34.5 10.2 79.3 13.1 35.9 49.8 13.0 20.4 51.2 4.6 20.7 3.6 5.6 5.9 2.9 7.6 4.9 6.7 6.0 3.2 6.2 6.2 7.2 18.9 3.2 3.1 8.9 4.1 3.8 80.3 84.6 58.7 92.7 87.7 81.1 80.3 74.7 83.9 62.9 80.3 76.9 21.1 16.0 17.8 9.4 9.3 12.0 10.1 9.2 6.8 50.4 15.6 16.9 39.7 12.8 8.8 11.0 8.4 10.6 23.0 69.8 11.7 18.0 3.0 30.1 13.3 16.8 19.2 11.0 12.8 35.4 12.3 20.3 11.7 19.5 8.2 8.2 28.2 61.4 15.7 126.2 10.1 29.2 20.3 18.6 9.7 4.1 18.6 12.8 7.2 2.8 14.0 71.3 20.6 4.5 6.6 33.8 27.4 21.4 9.7 10.8 62.3 37.6 22.9 38.0 6.6 16.3 19.9 7.0 12.8 21.0 18.9 9.2 12.9 21.8 28.4 9.4 TRA2A "AWMS1, htra-2-alpha" ENSG00000164548 "Transformer 2 alpha homolog" Q13595 7 23504780-23532041 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054018 Uncertain Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Nucleoli "Nucleoplasm, Vesicles" "HPA054018: AB_2682344" "unprognostic (2.55e-2)" "unprognostic (2.16e-1)" "unprognostic (1.24e-1)" "unprognostic (6.77e-3)" "unprognostic (8.05e-2)" "unprognostic (3.41e-2)" "prognostic unfavorable (2.07e-5)" "unprognostic (1.28e-2)" "unprognostic (2.50e-2)" "unprognostic (4.64e-2)" "unprognostic (1.87e-3)" "unprognostic (6.04e-2)" "prognostic unfavorable (1.79e-6)" "unprognostic (1.46e-2)" "unprognostic (1.52e-2)" "unprognostic (8.74e-2)" "unprognostic (1.36e-3)" 35.1 39.1 55.7 37.0 58.2 113.4 32.1 57.4 75.7 47.1 57.9 38.7 26.4 42.8 43.9 47.3 42.7 21.3 30.4 55.3 57.8 45.9 34.9 33.5 47.6 57.2 56.5 53.1 32.6 25.6 40.4 32.9 57.6 41.3 39.2 42.0 33.2 22.1 23.1 42.8 36.8 41.0 56.6 52.8 33.0 30.9 56.8 46.1 35.9 21.3 53.6 37.9 42.9 64.9 57.2 61.2 94.1 148.4 49.1 30.9 60.4 71.4 33.6 70.5 57.4 51.2 76.4 107.4 39.9 53.7 82.3 92.1 115.6 66.9 88.4 64.6 65.7 65.9 67.9 81.8 52.0 78.0 59.2 37.1 44.9 53.1 66.1 62.7 80.9 46.7 129.5 51.0 79.7 55.6 96.5 128.7 84.5 69.5 62.5 106.1 74.8 64.3 81.8 81.0 80.7 65.8 66.0 75.8 49.8 69.1 59.6 85.5 73.8 55.4 79.0 51.0 83.4 56.6 76.1 86.9 47.7 103.8 75.3 16.8 17.1 23.6 24.6 28.8 21.6 17.6 23.3 23.1 20.6 16.1 19.6 23.7 25.4 19.1 27.0 30.0 25.2 10.2 55.7 58.2 57.4 75.7 55.3 57.8 57.2 56.5 57.6 56.6 56.8 64.9 110.6 60.9 72.2 112.3 141.9 104.4 95.6 61.7 94.4 54.5 118.5 74.8 42.5 60.1 60.8 88.3 52.1 83.2 153.3 84.9 25.4 54.8 62.1 155.7 137.1 74.8 118.5 77.5 113.1 43.9 84.6 91.5 89.2 166.7 86.7 62.5 84.6 71.4 54.8 37.0 115.4 100.3 48.8 89.5 125.4 23.7 65.0 88.9 56.9 107.7 71.5 48.1 70.0 203.1 245.1 59.2 92.0 67.7 125.4 97.7 59.7 41.8 71.3 101.8 72.3 119.2 88.2 99.8 65.0 138.6 113.1 117.9 130.4 49.1 112.6 92.1 TRAF3IP2 "ACT1, C6orf2, C6orf4, C6orf5, C6orf6, CIKS, DKFZP586G0522" ENSG00000056972 "TRAF3 interacting protein 2" O43734 6 111555381-111606906 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Inflammatory response, Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 61.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-2197: 149.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA036352 Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 68: Epididymis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Golgi apparatus" Vesicles "HPA036352: AB_10672085" "unprognostic (1.94e-1)" "prognostic unfavorable (3.21e-4)" "unprognostic (1.79e-1)" "prognostic favorable (4.73e-5)" "unprognostic (2.81e-2)" "unprognostic (3.03e-2)" "unprognostic (1.01e-2)" "unprognostic (9.93e-2)" "unprognostic (2.10e-1)" "unprognostic (1.13e-2)" "unprognostic (2.64e-2)" "unprognostic (1.05e-2)" "prognostic unfavorable (5.16e-5)" "unprognostic (1.11e-1)" "unprognostic (4.88e-1)" "unprognostic (2.34e-2)" "unprognostic (1.31e-1)" 19.7 16.3 24.8 19.5 24.8 32.4 19.9 24.3 29.4 24.9 23.7 34.0 28.6 36.2 47.2 26.5 34.7 14.2 8.3 24.4 26.0 9.3 8.6 17.5 16.3 27.2 28.2 13.9 21.6 13.6 9.3 14.2 25.6 19.2 26.4 5.9 25.3 30.8 11.4 35.0 25.1 22.1 21.7 6.8 35.5 3.0 28.7 21.0 14.8 14.8 22.5 26.5 18.1 22.9 32.2 11.0 6.8 15.7 35.9 39.0 15.6 39.8 62.2 9.9 14.1 8.7 14.1 6.2 13.2 33.5 35.5 58.2 8.0 86.2 18.4 43.2 11.6 12.7 10.6 11.9 13.9 6.9 22.6 47.1 57.5 29.9 110.1 24.9 20.0 15.2 13.6 1.9 13.2 22.0 51.2 19.4 9.0 30.6 8.8 53.3 12.4 2.7 29.5 52.4 27.3 6.9 12.1 71.8 47.8 12.7 31.6 18.0 9.2 19.2 7.6 149.7 35.5 0.8 12.4 16.8 45.8 10.8 50.1 25.8 2.5 5.3 3.8 0.8 12.7 6.4 7.6 5.6 2.6 8.6 7.6 7.4 3.5 5.7 0.3 0.8 17.9 3.1 24.8 24.8 24.3 29.4 24.4 26.0 27.2 28.2 25.6 21.7 28.7 22.9 24.7 3.2 13.8 26.1 10.8 30.1 61.5 46.3 11.4 7.5 8.3 8.6 4.9 7.2 21.6 3.7 12.5 19.3 3.8 30.0 5.9 35.4 0.1 20.9 14.5 18.3 13.2 5.2 5.9 31.9 28.8 14.4 18.3 32.7 20.2 7.7 3.9 5.5 6.0 6.7 10.8 16.9 16.2 1.3 10.7 0.5 7.2 5.8 12.4 7.5 6.2 14.2 8.2 19.6 6.6 20.2 26.3 7.5 4.5 42.9 18.5 5.9 18.3 5.5 0.0 14.7 10.5 0.8 2.1 16.2 24.6 20.9 7.9 4.6 21.9 45.0 TRAF3IP3 T3JAM ENSG00000009790 "TRAF3 interacting protein 3" Q9Y228 1 209756032-209782320 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 130.5" "Cell type enhanced" "Detected in many" "B-cells: 133.8;dendritic cells: 124.7;NK-cells: 407.8;T-cells: 162.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 115.2;JURKAT: 64.2;Karpas-707: 46.2;MOLT-4: 60.9;NB-4: 68.7;THP-1: 64.1;U-266/70: 68.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA040796 Enhanced Approved Vesicles NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA040796: AB_10794861" "prognostic favorable (4.11e-4)" "unprognostic (1.11e-1)" "unprognostic (1.51e-3)" "unprognostic (1.36e-4)" "unprognostic (2.67e-1)" "unprognostic (1.91e-5)" "unprognostic (3.83e-3)" "prognostic favorable (8.15e-4)" "unprognostic (5.30e-2)" "unprognostic (3.72e-2)" "unprognostic (5.00e-2)" "unprognostic (2.39e-1)" "unprognostic (1.38e-4)" "unprognostic (3.08e-1)" "unprognostic (2.93e-2)" "unprognostic (3.16e-2)" "unprognostic (4.21e-2)" 3.6 2.3 1.9 51.6 2.0 31.8 4.1 1.8 4.2 3.5 1.4 8.2 7.4 2.8 2.7 3.4 2.0 10.5 1.7 2.0 2.0 4.2 5.7 10.8 99.7 3.0 2.6 2.1 0.9 0.7 0.8 2.0 3.0 3.4 10.4 0.3 5.6 2.8 1.1 2.4 30.6 3.8 2.3 60.1 13.4 3.8 3.0 130.5 3.0 1.9 90.5 11.7 2.2 3.7 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 115.2 0.0 11.0 0.0 0.0 0.2 17.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 64.2 0.1 46.2 0.0 0.0 60.9 68.7 0.2 0.0 0.0 7.1 0.0 20.8 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 64.1 0.0 0.0 0.1 0.0 0.1 68.1 25.6 4.7 0.0 31.9 0.1 456.2 155.3 169.6 296.7 171.1 317.7 300.5 410.4 343.1 164.1 287.8 459.3 365.0 41.2 345.1 209.8 121.6 587.1 414.3 1.9 2.0 1.8 4.2 2.0 2.0 3.0 2.6 3.0 2.3 3.0 3.7 1.6 3.2 9.6 0.3 133.8 2.3 4.8 1.2 1.2 1.7 1.5 1.9 0.7 2.8 0.2 0.0 0.0 0.5 124.7 0.4 11.7 0.1 11.3 14.8 0.9 2.1 0.0 22.9 0.4 0.2 0.3 1.4 2.0 48.0 58.2 0.0 6.1 3.8 22.3 0.0 0.4 0.4 0.0 24.7 12.6 9.0 0.3 40.8 10.6 39.4 69.8 0.2 407.8 0.0 0.7 0.0 0.1 0.0 64.1 2.4 0.4 12.8 0.9 0.4 0.0 0.7 1.2 8.0 0.6 2.6 2.3 0.4 162.8 0.0 0.6 1.8 TRAF7 "DKFZp586I021, MGC7807, RFWD1, RNF119" ENSG00000131653 "TNF receptor associated factor 7" Q6Q0C0 16 2155698-2178129 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041229 Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Vesicles "Plasma membrane" "HPA041229: AB_10794194" "unprognostic (1.94e-1)" "unprognostic (5.97e-2)" "unprognostic (1.13e-1)" "unprognostic (4.23e-2)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (1.65e-2)" "unprognostic (2.77e-3)" "unprognostic (7.08e-2)" "unprognostic (3.52e-2)" "unprognostic (1.52e-2)" "unprognostic (1.08e-1)" "unprognostic (9.23e-2)" "unprognostic (6.07e-2)" "unprognostic (2.99e-2)" "unprognostic (2.43e-1)" "unprognostic (8.48e-2)" 29.1 29.4 16.5 24.4 15.1 35.0 28.2 18.2 23.0 32.1 17.0 38.0 40.0 31.2 11.6 54.6 30.4 22.2 21.3 17.9 14.6 28.1 51.5 33.2 22.9 17.8 15.3 23.5 37.4 14.6 32.1 20.6 14.8 27.0 17.4 8.5 34.7 16.5 30.4 47.7 35.2 18.8 14.2 34.5 35.6 14.8 17.7 19.1 25.6 9.9 18.6 34.5 34.8 14.3 57.7 72.2 40.3 72.5 40.8 76.5 47.4 43.4 53.9 49.9 44.6 88.2 72.1 36.6 50.2 55.4 31.8 65.9 38.1 76.8 18.8 58.3 48.8 52.4 98.5 68.3 53.8 56.3 72.7 76.2 62.8 48.1 62.6 41.0 97.4 70.6 57.1 47.9 48.2 131.1 58.3 65.2 79.7 78.7 34.8 107.4 66.7 74.2 40.2 30.4 80.9 67.2 36.3 68.5 48.6 20.9 78.1 68.2 74.3 60.2 83.9 56.7 48.2 69.2 55.0 48.4 34.4 35.9 47.8 4.0 9.1 7.3 4.5 12.4 4.3 5.5 4.4 4.7 11.2 3.9 3.1 3.8 6.2 2.9 8.9 5.3 6.5 5.3 16.5 15.1 18.2 23.0 17.9 14.6 17.8 15.3 14.8 14.2 17.7 14.3 18.9 0.0 9.2 12.4 18.2 28.8 21.1 34.2 22.8 15.9 31.6 27.9 4.9 21.5 20.8 14.7 6.2 23.5 17.4 56.4 17.6 39.0 5.0 23.6 34.6 26.5 34.0 33.6 8.9 59.0 36.3 19.0 38.7 27.9 9.5 22.1 26.0 32.3 42.2 37.0 8.2 38.7 34.6 41.8 21.3 13.1 24.8 26.8 10.6 8.4 33.9 12.6 6.2 6.6 4.9 53.0 43.6 22.2 24.0 33.8 80.0 29.2 19.7 10.9 6.6 11.9 18.3 8.5 25.3 50.7 32.5 26.7 16.0 29.0 42.5 38.5 TRAK2 "ALS2CR3, CALS-C, GRIF-1, KIAA0549, MILT2, OIP98" ENSG00000115993 "Trafficking kinesin protein 2" O60296 2 201377207-201451500 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 102.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 157.8;Erythroid cells: 181.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015827, HPA062163" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Nuclear bodies" Vesicles "HPA015827: AB_1858238, HPA062163: AB_2684702" "unprognostic (2.10e-1)" "unprognostic (1.39e-1)" "unprognostic (2.56e-2)" "unprognostic (4.31e-2)" "unprognostic (2.78e-1)" "unprognostic (1.76e-1)" "unprognostic (2.38e-2)" "unprognostic (3.08e-2)" "unprognostic (2.24e-1)" "unprognostic (1.76e-2)" "unprognostic (1.68e-1)" "unprognostic (1.31e-1)" "prognostic favorable (7.42e-5)" "unprognostic (1.48e-1)" "unprognostic (3.24e-1)" "unprognostic (1.40e-2)" "unprognostic (9.82e-3)" 24.1 20.3 53.2 16.4 63.7 52.2 14.8 61.2 60.9 16.1 55.6 22.4 13.4 14.3 13.0 16.7 13.9 18.7 70.9 47.3 54.0 23.7 14.1 20.7 17.3 92.9 67.6 9.7 15.4 26.6 12.4 23.7 86.8 12.8 22.8 20.1 26.4 15.2 14.8 8.1 16.1 20.4 99.9 18.1 12.2 7.8 69.7 12.4 34.9 26.8 13.6 15.7 9.0 102.2 11.6 15.5 9.4 34.3 61.6 87.4 10.6 39.2 32.8 27.4 31.9 24.4 9.8 7.1 16.3 50.6 26.4 11.2 20.0 12.9 43.5 21.4 13.0 15.5 25.6 15.9 33.8 12.3 18.4 48.4 10.8 28.8 22.2 27.5 40.4 11.0 12.4 26.9 55.8 16.6 9.6 6.9 10.6 11.3 32.7 12.1 24.9 10.6 21.9 15.6 18.6 24.0 21.0 15.5 63.6 13.6 12.4 12.4 50.2 44.2 16.6 31.0 25.7 16.2 30.2 8.3 37.2 18.2 24.4 2.6 5.5 6.2 7.8 7.0 7.3 9.3 10.1 6.7 4.3 14.2 6.9 7.3 3.4 11.1 6.5 2.3 12.6 6.0 53.2 63.7 61.2 60.9 47.3 54.0 92.9 67.6 86.8 99.9 69.7 102.2 34.0 16.0 29.8 37.5 17.8 8.3 3.4 6.3 11.4 45.4 14.4 8.8 157.8 22.8 13.4 9.2 73.0 10.3 9.3 27.9 7.9 13.9 1.9 12.7 20.9 21.0 29.5 181.0 92.3 14.7 4.8 16.9 10.7 25.7 19.6 10.3 15.0 14.3 10.6 77.4 75.6 20.6 10.2 12.9 7.7 3.8 8.1 13.2 26.6 22.5 14.2 5.1 12.3 47.7 57.0 10.7 14.5 12.8 16.8 5.7 21.7 8.9 14.9 22.1 13.1 23.2 23.3 9.4 12.8 16.2 4.1 5.6 16.6 18.7 24.5 7.2 TRAPPC11 "C4orf41, FLJ12716, foigr, gry" ENSG00000168538 "Trafficking protein particle complex 11" Q7Z392 4 183659267-183713594 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "ER-Golgi transport, Transport" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038173 Approved Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" Cytosol Vesicles "HPA038173: " "unprognostic (2.24e-1)" "unprognostic (6.03e-2)" "unprognostic (9.92e-3)" "unprognostic (1.31e-2)" "unprognostic (1.08e-1)" "unprognostic (1.00e-1)" "unprognostic (9.14e-2)" "unprognostic (6.24e-2)" "unprognostic (2.63e-1)" "unprognostic (6.50e-2)" "unprognostic (5.78e-2)" "unprognostic (2.17e-1)" "prognostic favorable (2.66e-5)" "unprognostic (6.59e-2)" "unprognostic (1.59e-1)" "unprognostic (2.25e-2)" "unprognostic (3.92e-2)" 12.1 15.9 4.3 13.4 5.5 11.4 15.5 8.3 6.4 12.4 15.4 13.2 11.0 14.1 11.8 13.8 12.4 11.0 12.4 5.5 4.8 14.8 16.9 13.6 14.9 3.4 4.1 20.8 14.2 19.1 6.8 13.8 3.7 14.1 15.0 13.8 14.8 12.1 15.1 12.1 11.7 15.7 4.4 14.2 13.5 16.0 4.9 17.8 14.8 18.7 17.6 13.6 8.0 6.0 15.1 14.4 23.2 23.1 28.5 31.3 17.6 21.6 21.7 17.8 16.2 9.0 19.1 20.7 6.0 21.8 13.9 10.8 21.2 20.5 20.4 23.1 9.3 26.0 12.0 12.8 26.2 28.3 24.8 24.2 21.5 17.8 20.6 23.2 26.5 23.9 21.1 41.8 22.5 10.8 34.1 13.8 8.7 10.2 10.7 23.4 13.8 15.8 22.8 15.3 15.6 20.7 21.1 21.6 21.4 20.5 16.6 31.0 26.7 10.1 11.9 9.7 12.4 21.8 12.7 12.4 20.6 18.7 18.0 3.8 12.9 8.2 5.7 14.9 7.6 4.7 6.2 6.1 12.8 3.4 5.7 5.9 3.7 10.0 25.6 3.3 5.4 7.6 4.3 5.5 8.3 6.4 5.5 4.8 3.4 4.1 3.7 4.4 4.9 6.0 9.5 3.2 14.5 33.0 12.3 4.5 3.1 7.4 9.1 11.0 5.7 6.2 14.8 8.6 9.1 7.3 8.4 7.9 10.0 9.8 3.9 7.4 57.7 8.2 13.3 9.1 13.1 12.0 47.5 9.3 8.4 12.0 12.2 8.0 7.6 18.7 9.3 8.5 11.6 8.4 47.4 7.2 0.0 16.0 6.8 7.3 13.4 16.1 3.6 30.0 19.5 6.4 11.3 37.2 35.2 9.0 7.1 11.3 10.6 5.5 11.7 4.6 12.9 13.6 0.0 9.9 8.6 7.7 14.9 10.4 6.1 7.0 9.4 12.4 7.9 5.9 TRAPPC2 "hYP38334, MIP-2A, SEDL, SEDT, TRS20, ZNF547L" ENSG00000196459 "Trafficking protein particle complex 2" P0DI81 X 13712244-13734635 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "ER-Golgi transport, Transcription, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "CAB004665, HPA063308" Approved Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Endoplasmic reticulum, Vesicles" Nucleoplasm "CAB004665: AB_425678, HPA063308: AB_2684982" "unprognostic (1.97e-1)" "prognostic favorable (8.09e-4)" "unprognostic (2.13e-1)" "unprognostic (4.18e-1)" "unprognostic (2.11e-1)" "unprognostic (2.70e-2)" "unprognostic (1.04e-2)" "unprognostic (2.08e-3)" "unprognostic (1.76e-2)" "prognostic favorable (6.35e-4)" "unprognostic (3.50e-2)" "unprognostic (8.24e-2)" "unprognostic (1.93e-1)" "unprognostic (2.09e-1)" "unprognostic (4.53e-2)" "unprognostic (2.36e-1)" "prognostic favorable (7.89e-5)" 6.0 5.7 12.5 6.7 13.4 7.6 6.8 13.1 14.2 10.0 10.7 10.9 6.0 11.0 6.3 8.4 9.4 5.5 5.3 13.3 13.9 7.4 8.2 7.5 12.7 12.1 11.2 11.2 9.2 5.2 7.7 5.3 12.5 8.3 6.4 10.2 7.3 5.1 4.4 7.4 9.6 8.8 10.2 10.3 9.7 3.2 14.9 9.0 7.8 2.7 11.8 8.9 9.9 11.8 9.1 6.2 10.5 26.1 8.0 5.9 3.7 8.5 7.8 6.7 6.9 5.8 11.0 14.8 13.2 6.9 8.8 11.0 13.8 12.4 8.6 15.3 20.4 11.3 16.0 5.2 6.4 15.9 20.8 8.0 7.0 14.7 17.1 13.4 6.3 11.1 15.0 26.3 7.3 16.0 16.0 21.7 10.6 7.2 11.4 15.3 14.3 14.6 10.8 5.5 10.6 13.6 14.5 12.1 11.0 16.3 13.5 10.6 7.9 6.7 6.2 11.4 5.5 13.3 13.8 19.6 6.0 10.5 6.4 19.3 6.0 11.0 18.1 8.4 18.2 13.2 14.3 17.8 5.5 12.8 11.8 16.6 11.7 22.9 6.9 13.0 18.7 11.1 12.5 13.4 13.1 14.2 13.3 13.9 12.1 11.2 12.5 10.2 14.9 11.8 8.9 9.6 6.5 7.8 22.0 15.2 10.0 14.8 9.6 16.5 16.5 13.6 11.0 15.7 14.6 9.2 12.5 14.1 49.8 14.6 21.5 10.0 17.7 17.3 11.0 9.3 12.1 12.4 20.7 13.4 19.9 11.5 14.8 21.2 9.5 16.9 16.8 12.2 11.6 20.2 20.2 14.0 8.2 12.9 14.4 6.1 12.8 13.6 8.8 10.3 12.0 8.8 44.3 31.7 17.3 15.7 18.6 11.3 17.6 9.8 15.4 23.8 8.5 14.5 6.6 8.6 18.5 4.3 4.0 11.3 17.6 17.9 28.8 16.6 13.2 12.5 TRAPPC2B "MIP-2A, SEDLP, SEDLP1, TRAPPC2P1" ENSG00000256060 "Trafficking protein particle complex 2B" P0DI82 19 57363551-57365405 "Predicted intracellular proteins" "ER-Golgi transport, Transcription, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 91.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063308 Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Endoplasmic reticulum, Vesicles" Nucleoplasm "HPA063308: AB_2684982" "unprognostic (8.55e-2)" "unprognostic (1.07e-2)" "unprognostic (4.24e-1)" "unprognostic (5.27e-2)" "unprognostic (1.93e-1)" "unprognostic (6.69e-2)" "unprognostic (1.12e-1)" "unprognostic (4.47e-2)" "unprognostic (4.57e-2)" "unprognostic (3.24e-2)" "unprognostic (1.47e-1)" "unprognostic (2.05e-1)" "prognostic favorable (1.28e-4)" "unprognostic (1.26e-1)" "unprognostic (4.49e-2)" "unprognostic (9.74e-2)" "unprognostic (1.39e-2)" 15.0 20.6 8.3 6.8 8.8 10.6 14.2 10.6 11.5 7.9 9.5 13.0 5.0 10.6 11.0 12.5 9.8 9.8 19.5 8.5 9.5 12.5 11.0 10.4 12.3 8.4 8.6 12.8 7.3 10.8 14.9 10.8 9.0 10.1 5.7 8.6 10.9 6.7 30.2 11.6 8.6 9.2 8.2 13.3 9.5 23.2 8.9 15.2 12.2 17.0 10.7 12.4 8.5 8.6 16.9 11.9 18.0 12.0 16.2 18.9 16.2 11.5 25.9 16.6 48.6 6.4 12.5 13.0 15.3 14.9 28.3 6.1 8.4 18.5 17.8 5.9 60.8 13.0 18.7 14.6 16.7 14.3 20.9 18.9 23.1 12.6 9.4 19.1 12.5 14.5 4.1 0.1 19.5 5.0 22.1 13.0 6.0 1.2 25.3 10.7 17.0 20.2 18.8 26.7 18.8 15.4 10.9 12.5 11.1 15.9 18.7 18.1 13.9 15.8 13.7 7.7 18.6 20.5 27.8 25.4 22.7 9.1 16.0 68.4 23.5 30.8 12.0 22.2 24.6 45.1 25.3 20.2 26.5 48.5 24.4 19.5 27.7 44.1 20.9 37.9 24.6 22.4 8.3 8.8 10.6 11.5 8.5 9.5 8.4 8.6 9.0 8.2 8.9 8.6 38.9 9.6 13.1 0.0 13.2 0.0 0.0 0.0 0.0 0.0 21.7 28.2 26.1 0.0 9.9 18.4 0.0 38.1 16.3 0.0 25.4 32.9 0.0 29.3 13.4 15.4 0.0 0.0 0.0 22.1 18.3 10.3 0.0 25.7 21.5 18.2 0.0 0.0 32.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 11.9 0.0 0.0 0.0 0.0 28.7 0.0 0.0 4.4 0.0 0.0 17.0 13.1 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 91.9 11.7 32.7 0.0 0.0 TRAPPC2L HSPC176 ENSG00000167515 "Trafficking protein particle complex 2 like" Q9UL33 16 88856220-88862686 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "ER-Golgi transport, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 403.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041714 Approved Supported Vesicles,Cytosol NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Vesicles, Cytosol" "HPA041714: AB_10793930" "unprognostic (1.27e-2)" "unprognostic (2.32e-3)" "unprognostic (1.46e-1)" "prognostic favorable (3.75e-4)" "unprognostic (2.77e-1)" "unprognostic (2.69e-1)" "unprognostic (5.24e-3)" "unprognostic (2.90e-1)" "unprognostic (2.84e-1)" "unprognostic (6.53e-3)" "unprognostic (1.05e-1)" "unprognostic (2.81e-1)" "unprognostic (1.02e-2)" "unprognostic (1.18e-1)" "unprognostic (1.00e-1)" "unprognostic (5.81e-2)" "unprognostic (1.94e-2)" 55.4 134.3 55.1 30.9 56.7 36.9 51.5 57.4 69.8 49.1 55.2 46.0 25.3 46.7 60.3 53.8 44.1 19.9 66.4 57.8 61.9 53.5 46.5 42.7 31.1 57.5 57.9 55.8 48.8 58.1 45.3 20.4 59.1 39.2 23.8 25.6 48.0 20.5 96.8 58.5 39.1 18.1 60.0 52.7 62.8 122.0 56.9 50.0 41.8 70.7 27.2 48.5 47.3 65.4 69.9 47.9 79.6 60.8 58.5 73.9 81.5 61.5 69.4 92.6 35.4 133.6 89.6 53.4 105.8 78.6 97.7 73.3 109.5 88.5 67.0 46.9 65.7 35.3 46.1 172.7 86.3 101.4 27.5 72.2 54.7 125.4 63.1 52.4 75.7 118.7 108.2 41.4 64.3 216.2 136.1 311.7 80.3 133.4 88.6 128.9 65.9 55.4 73.1 79.6 85.8 42.2 207.6 63.5 59.0 43.6 162.5 106.3 60.3 61.1 66.7 81.1 71.2 57.9 106.6 254.5 73.3 148.0 74.5 39.2 136.3 40.8 113.0 114.5 115.0 154.2 129.8 124.1 135.1 137.9 120.8 103.5 23.9 94.6 114.8 162.5 178.0 162.9 55.1 56.7 57.4 69.8 57.8 61.9 57.5 57.9 59.1 60.0 56.9 65.4 66.2 57.7 82.0 2.3 58.7 51.9 57.4 115.4 43.3 34.9 80.1 106.3 121.1 92.9 81.1 53.3 10.4 93.8 58.2 75.3 240.7 134.7 219.1 60.9 53.4 60.7 62.1 42.1 4.0 154.8 141.5 79.2 72.9 50.5 36.1 55.9 62.8 123.9 226.7 15.2 5.1 78.5 75.3 91.0 69.6 403.2 74.0 68.4 81.8 1.9 134.4 87.3 79.3 2.5 13.0 137.4 76.3 58.3 92.6 45.3 122.5 271.7 93.5 39.5 59.2 44.1 94.7 210.7 123.1 86.0 64.9 77.6 61.2 64.6 86.8 62.5 TRAPPC3L "bA259P20.2, BET3L, FLJ11180" ENSG00000173626 "Trafficking protein particle complex 3 like" Q5T215 6 116494989-116545684 "Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.1" "Cell type enhanced" "Detected in some" "Adipocytes: 1.6;Early spermatids: 1.8;Endothelial cells: 1.5;Hepatic stellate cells: 6.1;Kupffer cells: 4.2;Macrophages: 3.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA060912 Approved "Golgi apparatus,Vesicles" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 6: Brain - Smell perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" "Golgi apparatus, Vesicles" "HPA060912: " "unprognostic (1.34e-1)" "unprognostic (7.24e-2)" "unprognostic (1.93e-2)" "unprognostic (2.91e-1)" "unprognostic (5.25e-2)" "unprognostic (1.15e-2)" "unprognostic (8.98e-2)" "unprognostic (9.09e-4)" "unprognostic (8.41e-2)" "unprognostic (3.23e-2)" "unprognostic (1.96e-1)" "unprognostic (2.91e-3)" "unprognostic (2.59e-3)" "unprognostic (1.21e-1)" "unprognostic (1.52e-1)" "unprognostic (8.11e-2)" "unprognostic (7.47e-3)" 0.7 0.7 1.6 0.8 1.7 3.7 1.0 8.1 5.0 0.4 0.3 0.7 1.0 1.2 1.8 0.7 0.5 1.1 0.9 2.3 0.0 0.7 1.4 1.2 1.7 0.6 0.1 1.0 0.7 3.0 0.0 3.9 1.6 0.7 0.5 4.2 1.2 0.7 1.2 2.3 1.0 0.4 0.1 4.7 1.1 1.5 0.7 0.5 1.8 0.2 0.6 0.5 0.0 3.9 0.8 0.4 1.0 1.5 0.3 1.0 1.1 0.5 0.5 0.4 0.5 0.5 0.7 1.3 0.6 0.2 0.8 1.0 0.3 0.6 0.5 0.6 0.6 1.4 1.9 0.6 0.5 0.9 0.6 0.4 0.3 0.2 0.3 1.5 0.8 1.0 0.8 6.6 0.3 1.5 0.9 1.0 0.9 0.3 0.6 0.8 0.7 2.2 0.7 1.3 1.0 0.7 0.8 0.4 0.5 1.2 0.7 0.8 1.0 1.2 0.9 1.2 0.6 1.2 0.8 0.8 0.8 0.9 0.7 0.6 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.9 0.1 0.2 0.3 0.1 2.8 1.6 1.7 8.1 5.0 2.3 0.0 0.6 0.1 1.6 0.1 0.7 3.9 1.6 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 1.5 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.4 6.1 0.1 1.1 0.0 0.1 0.0 0.0 4.2 0.0 0.4 0.3 3.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.2 0.1 0.0 0.1 0.0 0.1 0.5 0.0 0.0 TRAPPC5 "MGC52424, TRS31" ENSG00000181029 "Trafficking protein particle complex 5" Q8IUR0 19 7680833-7687703 "Predicted intracellular proteins" "ER-Golgi transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 57.5;Gastric mucus-secreting cells: 86.2;Plasma cells: 76.9;Squamous epithelial cells: 80.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 314.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042221, HPA049064" Uncertain Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 59: Non-specific - Transcription" Vesicles "HPA042221: AB_2677907, HPA049064: AB_2680618" "unprognostic (3.10e-2)" "unprognostic (5.09e-2)" "unprognostic (1.45e-1)" "unprognostic (1.12e-2)" "unprognostic (1.14e-1)" "unprognostic (3.21e-3)" "unprognostic (1.80e-1)" "unprognostic (2.86e-1)" "unprognostic (6.28e-2)" "unprognostic (2.55e-2)" "unprognostic (2.12e-2)" "unprognostic (6.82e-2)" "unprognostic (4.86e-8)" "unprognostic (3.09e-1)" "unprognostic (1.11e-1)" "unprognostic (6.08e-2)" "unprognostic (1.51e-1)" 58.9 86.8 65.7 25.6 68.7 62.7 58.4 67.1 112.6 55.6 60.6 53.0 27.6 52.1 8.1 85.6 44.7 13.8 105.1 69.4 74.7 75.7 99.7 35.9 23.4 64.5 68.9 50.1 67.1 19.9 58.4 19.1 70.5 71.1 8.4 9.0 64.8 17.2 112.4 90.6 48.5 11.5 64.3 60.6 57.5 181.4 65.9 16.8 56.0 27.3 12.2 55.5 56.2 64.4 61.0 129.4 20.7 56.9 16.3 24.1 62.1 47.1 33.8 45.3 46.1 76.9 41.2 62.9 92.0 32.7 25.8 55.2 13.0 47.2 8.9 48.3 199.2 23.7 86.7 163.7 56.8 42.1 45.3 40.0 61.9 34.6 15.8 15.4 57.6 64.3 34.3 89.3 22.3 190.7 72.3 148.8 66.1 27.1 314.1 46.6 28.8 91.1 50.7 142.8 54.1 47.0 40.1 74.6 69.1 7.1 60.1 44.3 58.8 54.2 44.9 103.3 47.7 80.8 44.2 44.3 75.3 51.2 74.2 207.5 373.4 151.4 116.7 394.1 112.3 313.7 145.0 129.3 442.0 289.2 141.7 124.7 518.4 97.4 365.5 188.8 222.5 329.3 65.7 68.7 67.1 112.6 69.4 74.7 64.5 68.9 70.5 64.3 65.9 64.4 1.8 3.2 3.6 15.3 36.1 1.9 1.2 2.4 57.5 5.1 6.3 4.2 1.0 1.5 5.1 5.5 2.1 3.5 1.2 26.7 0.0 26.9 13.3 3.8 4.8 5.6 11.4 41.0 13.5 19.3 5.3 14.3 86.2 3.7 1.3 2.0 8.2 13.4 9.9 8.4 16.4 15.7 0.0 18.8 3.3 44.4 1.5 52.2 1.8 11.2 17.0 1.5 4.1 11.6 22.8 19.8 26.3 3.4 76.9 1.9 28.0 9.2 2.6 4.8 0.0 1.4 8.4 5.0 1.2 80.1 1.7 3.4 18.0 2.7 14.1 1.5 TRAPPC9 "IKBKBBP, KIAA1882, MRT13, NIBP, T1, TRS120" ENSG00000167632 "Trafficking protein particle complex 9" Q96Q05 8 139727725-140458579 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 89.5;Excitatory neurons: 121.8;Inhibitory neurons: 136.3;Late spermatids: 119.0;Microglial cells: 105.9;Oligodendrocyte precursor cells: 93.5;Oligodendrocytes: 170.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026579 Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA026579: AB_1854459" "unprognostic (1.82e-2)" "unprognostic (1.06e-1)" "unprognostic (1.41e-1)" "unprognostic (1.48e-2)" "unprognostic (2.30e-1)" "unprognostic (1.12e-1)" "unprognostic (2.15e-1)" "unprognostic (8.14e-2)" "unprognostic (1.03e-1)" "unprognostic (1.96e-1)" "unprognostic (2.76e-2)" "unprognostic (2.31e-1)" "prognostic favorable (5.11e-6)" "unprognostic (2.09e-1)" "unprognostic (9.97e-2)" "unprognostic (2.40e-1)" "unprognostic (1.62e-1)" 8.6 13.4 10.3 6.9 11.0 11.1 8.9 10.7 12.7 10.3 12.5 11.1 8.0 11.3 5.1 12.3 12.2 5.8 15.0 10.8 10.3 13.8 11.6 9.5 8.0 13.1 14.1 10.5 11.9 27.4 20.7 7.2 13.9 11.7 6.0 14.2 11.6 8.3 33.5 11.4 10.9 7.2 10.2 11.3 12.5 9.0 11.9 11.3 12.9 17.6 6.8 11.1 10.8 13.0 9.6 16.6 7.4 20.8 15.5 9.0 4.9 6.0 9.9 3.1 5.0 6.2 11.2 11.6 14.0 11.9 4.7 12.2 10.0 9.4 3.4 16.8 6.1 18.6 9.8 6.2 11.2 4.7 14.5 8.9 9.3 2.5 7.9 11.1 12.9 13.1 6.7 10.1 5.1 27.0 29.2 6.2 2.3 31.3 14.0 12.2 2.7 19.4 11.6 11.6 19.1 10.6 9.8 4.7 10.6 7.6 15.3 6.8 7.7 4.6 7.9 10.8 4.9 14.1 10.9 7.8 9.6 10.1 7.4 15.4 3.5 2.9 4.2 3.3 4.6 2.7 2.9 3.3 3.5 4.4 2.8 3.6 5.0 4.9 3.4 4.2 2.1 3.5 10.3 11.0 10.7 12.7 10.8 10.3 13.1 14.1 13.9 10.2 11.9 13.0 5.1 3.2 8.3 89.5 9.6 2.3 4.7 3.1 5.7 14.2 5.5 4.1 13.9 5.7 5.3 11.0 20.9 10.9 5.4 15.2 9.8 6.5 47.9 8.4 3.7 6.5 30.5 3.4 121.8 6.2 4.4 5.3 29.6 10.2 8.8 7.9 4.6 9.2 7.5 28.6 136.3 14.4 10.2 10.5 3.7 119.0 5.9 10.3 10.6 105.9 5.3 13.6 11.3 93.5 170.6 5.1 6.6 7.9 11.0 3.7 13.4 19.9 15.7 13.7 6.6 9.0 5.3 3.6 6.6 8.7 3.0 14.6 10.5 8.6 12.0 5.4 TREH "MGC129621, TRE, TREA" ENSG00000118094 Trehalase O43280 11 118657316-118679690 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 66.3" "Group enriched" "Detected in some" 5 "Late spermatids: 315.7;Proximal enterocytes: 186.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "BEWO: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039913, HPA042045" Enhanced Approved Vesicles,Cytosol "Intracellular and membrane" NA NA 12000000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 45: Enterocytes - Digestion" Cytosol Vesicles "HPA039913: AB_10674988, HPA042045: AB_2677817" "unprognostic (1.29e-1)" "unprognostic (1.58e-1)" "unprognostic (1.01e-2)" "unprognostic (5.22e-4)" "unprognostic (2.52e-1)" "unprognostic (9.83e-2)" "prognostic favorable (3.76e-4)" "unprognostic (1.17e-1)" "unprognostic (1.34e-1)" "unprognostic (2.42e-1)" "unprognostic (1.04e-1)" "unprognostic (1.63e-2)" "prognostic favorable (2.33e-6)" "unprognostic (2.09e-2)" "unprognostic (6.30e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-1)" 0.7 0.2 1.6 0.3 3.7 0.0 0.4 0.6 3.8 0.3 0.0 1.6 60.0 0.4 0.6 1.6 0.3 2.6 1.0 1.1 2.7 13.4 6.1 0.2 0.1 2.1 2.0 0.2 1.8 0.0 0.3 0.1 1.9 0.5 1.3 0.0 0.2 0.0 0.0 0.1 66.3 0.1 0.6 0.1 1.7 1.8 2.5 0.0 0.4 0.0 0.0 0.4 0.3 6.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.5 0.0 0.4 0.0 0.2 0.0 0.2 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 3.7 0.6 3.8 1.1 2.7 2.1 2.0 1.9 0.6 2.5 6.0 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.8 0.0 0.0 0.3 0.3 1.5 0.0 1.8 0.0 0.1 0.0 2.3 7.9 0.2 45.6 0.8 1.6 0.1 3.0 0.0 0.1 2.5 0.0 0.3 4.6 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 7.0 0.0 0.0 0.4 315.7 2.1 0.1 0.0 0.0 0.0 0.0 0.0 1.5 5.3 0.9 6.3 1.9 0.1 0.3 186.3 32.8 0.0 0.0 0.0 0.3 0.2 1.7 0.8 2.1 0.0 0.0 0.1 0.0 3.7 0.0 TRIM17 "RBCC, RNF16, terf" ENSG00000162931 "Tripartite motif containing 17" Q9Y577 1 228407935-228416861 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 42.0" "Group enriched" "Detected in some" 27 "Early spermatids: 291.1;Late spermatids: 87.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 4.4;HEL: 2.1;NTERA-2: 1.9;SH-SY5Y: 2.3;T-47d: 5.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" HPA054908 Approved Approved Vesicles NA NA "Cluster 24: B-cells - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA054908: AB_2682638" "prognostic favorable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (3.06e-2)" "unprognostic (5.45e-2)" "unprognostic (1.25e-1)" "unprognostic (7.74e-3)" "unprognostic (7.42e-3)" "unprognostic (2.02e-1)" "unprognostic (1.17e-2)" "unprognostic (8.91e-2)" "unprognostic (2.23e-1)" "unprognostic (2.04e-1)" "unprognostic (5.96e-4)" "unprognostic (3.88e-1)" "unprognostic (4.88e-2)" "unprognostic (6.33e-2)" "unprognostic (3.64e-1)" 2.1 1.2 3.2 0.3 6.3 0.2 2.9 10.2 4.9 3.0 1.1 0.6 0.2 2.0 0.4 1.9 3.9 0.4 1.7 4.8 1.4 3.0 0.2 1.5 0.6 1.3 0.9 3.2 0.6 1.6 2.1 0.3 0.8 4.1 0.0 0.2 4.6 0.7 0.1 2.2 1.0 0.2 0.0 6.4 1.0 42.0 2.6 0.0 3.1 0.0 0.2 1.6 3.2 1.0 0.1 0.4 0.2 0.2 0.0 0.0 4.4 0.3 0.0 0.0 0.0 1.0 0.5 0.0 1.0 0.0 0.1 1.1 0.0 0.0 0.1 0.1 0.4 2.1 0.7 0.1 0.8 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.3 0.0 0.1 0.2 0.0 1.9 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.3 2.3 0.0 0.2 0.0 0.4 5.6 0.1 0.0 0.2 0.9 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 3.2 6.3 10.2 4.9 4.8 1.4 1.3 0.9 0.8 0.0 2.6 1.0 0.0 0.0 0.5 0.3 0.1 0.3 1.7 0.1 2.8 1.0 0.6 0.9 1.5 0.0 1.5 1.8 0.0 0.0 0.9 0.1 0.0 0.7 291.1 1.2 1.3 0.3 0.0 0.0 7.0 0.0 0.0 1.1 0.0 0.8 0.0 0.3 0.0 0.0 0.1 0.0 1.2 0.0 0.0 0.0 0.0 87.9 1.2 0.1 0.0 1.0 0.0 0.5 1.0 0.5 0.9 0.6 0.0 0.4 0.1 0.7 0.0 0.0 2.4 0.0 0.0 0.1 0.3 2.5 1.8 0.2 0.3 0.8 0.9 0.0 0.0 0.6 TRIM33 "FLJ11429, KIAA1113, PTC7, RFG7, TF1G, TIF1G, TIF1GAMMA, TIFGAMMA" ENSG00000197323 "Tripartite motif containing 33" Q9UPN9 1 114392790-114511203 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 237.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 13.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 115.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004345 Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" Vesicles Nucleoplasm "HPA004345: AB_1858287" "unprognostic (8.90e-2)" "unprognostic (5.86e-2)" "prognostic favorable (6.20e-4)" "unprognostic (1.09e-2)" "unprognostic (8.42e-3)" "prognostic favorable (8.93e-4)" "unprognostic (1.34e-2)" "unprognostic (1.83e-1)" "unprognostic (6.75e-2)" "unprognostic (4.58e-2)" "unprognostic (2.14e-1)" "unprognostic (1.08e-1)" "unprognostic (2.27e-2)" "unprognostic (4.84e-2)" "unprognostic (1.99e-1)" "unprognostic (1.40e-1)" "unprognostic (1.68e-1)" 9.3 8.1 10.1 10.7 11.3 25.4 13.5 18.3 16.9 12.5 8.2 9.5 8.8 15.2 29.8 11.7 9.1 10.9 8.9 11.5 9.9 13.5 12.2 10.9 13.3 8.0 9.1 14.4 12.2 15.3 7.3 16.0 8.2 12.6 10.1 18.8 10.7 11.0 8.8 14.8 8.9 11.8 8.1 12.7 11.2 25.3 9.5 17.8 14.2 10.7 12.8 11.5 9.8 11.3 30.9 16.3 30.1 22.6 12.5 13.1 51.0 15.4 16.3 20.9 22.1 18.5 12.8 32.8 15.5 18.1 13.6 17.4 27.6 18.0 28.6 24.9 16.4 31.6 21.7 21.6 13.8 40.3 25.3 12.5 12.9 24.9 25.2 16.0 17.8 27.3 40.1 22.5 20.2 115.4 40.9 17.0 40.7 11.7 16.3 34.8 45.9 10.8 14.9 47.7 20.8 21.9 29.2 34.7 27.4 19.3 15.8 21.7 20.1 14.5 23.4 33.8 21.7 15.7 15.6 33.4 20.4 23.0 42.0 13.2 1.2 6.1 2.5 1.5 2.2 3.0 2.6 2.7 1.5 1.4 2.0 3.1 3.6 4.1 2.4 3.0 1.6 0.8 10.1 11.3 18.3 16.9 11.5 9.9 8.0 9.1 8.2 8.1 9.5 11.3 31.0 19.2 33.3 70.5 35.4 52.8 28.9 28.6 25.6 75.6 35.9 23.9 29.2 30.0 32.3 55.2 98.0 64.9 53.9 33.3 1.9 21.0 237.3 50.4 37.5 33.2 52.1 37.9 120.7 23.6 34.0 28.7 30.1 90.0 37.4 55.6 40.7 44.3 29.6 26.9 108.5 30.4 30.5 50.3 47.9 97.9 49.0 37.2 19.6 79.6 42.9 31.5 54.6 116.6 101.8 31.4 34.9 36.9 31.6 47.3 26.6 17.3 31.4 58.3 32.9 38.3 32.5 60.0 31.9 31.2 55.4 87.7 42.8 48.1 31.2 55.3 TRIM44 "DIPB, MC7" ENSG00000166326 "Tripartite motif containing 44" Q96DX7 11 35662775-35818007 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049053, HPA057633" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 77: Retina - Visual perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "Plasma membrane" "HPA049053: AB_2680613, HPA057633: AB_2683484" "unprognostic (2.73e-1)" "unprognostic (2.74e-1)" "unprognostic (1.37e-1)" "unprognostic (5.53e-2)" "unprognostic (3.91e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (5.24e-5)" "unprognostic (9.06e-2)" "unprognostic (5.29e-2)" "unprognostic (2.67e-1)" "unprognostic (1.02e-1)" "unprognostic (8.57e-2)" "unprognostic (1.49e-3)" "unprognostic (2.15e-2)" "unprognostic (1.59e-1)" "unprognostic (1.52e-1)" "unprognostic (3.00e-1)" 12.6 10.7 16.9 12.3 16.4 6.0 11.1 18.5 21.9 10.9 8.3 13.5 10.6 10.9 10.2 9.1 11.1 11.6 11.6 16.6 17.0 18.0 14.4 11.9 12.8 16.0 16.7 10.3 15.5 11.1 7.9 13.3 16.1 10.4 11.1 27.0 9.4 11.4 11.5 8.3 12.0 12.2 17.8 14.1 11.3 6.7 17.3 12.1 14.9 9.8 13.2 11.1 8.6 19.0 20.1 16.9 26.4 12.3 19.6 29.6 0.1 18.5 21.9 22.7 20.6 19.7 13.3 26.7 17.1 24.3 25.7 15.4 9.1 21.1 25.4 17.6 17.4 28.7 23.0 11.4 26.0 22.7 23.7 22.4 23.2 13.3 36.0 25.1 24.3 9.2 45.4 9.3 24.1 12.1 24.1 11.1 14.9 4.2 14.5 16.6 68.4 14.5 21.0 26.9 18.1 15.5 27.7 19.6 21.0 14.3 29.5 19.0 27.4 28.9 23.8 16.6 21.2 15.7 15.0 0.1 23.9 23.7 22.2 0.2 0.9 0.3 0.9 1.2 0.8 1.1 0.9 0.9 0.8 1.5 1.1 1.2 0.0 1.2 1.5 1.8 0.3 0.5 16.9 16.4 18.5 21.9 16.6 17.0 16.0 16.7 16.1 17.8 17.3 19.0 67.5 60.9 72.6 78.4 68.5 26.8 57.9 19.8 74.0 221.5 45.3 38.2 58.9 55.8 45.6 25.8 204.3 55.4 72.1 70.3 33.2 62.8 18.8 78.0 74.0 62.4 51.4 39.3 151.7 71.1 25.9 49.4 74.9 54.4 58.9 107.1 49.2 53.3 42.7 84.1 134.5 57.6 16.2 65.7 37.8 13.4 36.1 70.3 19.6 84.3 76.9 72.2 72.1 121.7 171.0 53.3 50.4 37.2 59.6 90.3 50.9 75.6 48.4 173.4 98.6 71.9 52.1 88.2 81.5 46.1 26.7 52.1 47.0 58.5 54.5 59.9 TRIM51 "SPRYD5, TRIM51A" ENSG00000124900 "Tripartite motif-containing 51" Q9BSJ1 11 55883297-55891810 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 50 "melanoma: 4.3" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 112 "basophil: 11.2" "Lineage enriched" "Detected in single" 112 "granulocytes: 11.2" "Cell line enriched" "Detected in some" 4 "SK-MEL-30: 61.3" "HPA044988, HPA077883" Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 38: Basophils - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 40: Granulosa cells - Unknown function" Vesicles Nucleoli "HPA044988: AB_2679171, HPA077883: AB_2732362" "unprognostic (9.60e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRIM51GP ENSG00000220948 "Tripartite motif-containing 51G, pseudogene" 11 48975324-48983826 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SK-MEL-30: 1.1" "HPA044988, HPA077883" Uncertain Approved Nucleoli,Vesicles NA NA "Cluster 33: SK-MEL-30 - Melanocyte processes" Vesicles Nucleoli "HPA044988: AB_2679171, HPA077883: AB_2732362" "unprognostic (2.95e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRIM62 "DEAR1, FLJ10759" ENSG00000116525 "Tripartite motif containing 62" Q9BVG3 1 33145399-33182059 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 21.0" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 50.8;Oligodendrocytes: 26.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "AF22: 23.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050061 Approved "Vesicles,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 68: Oligodendrocytes - Mixed function" "Vesicles, Focal adhesion sites" "HPA050061: AB_2681001" "unprognostic (1.57e-1)" "unprognostic (4.39e-2)" "unprognostic (2.39e-2)" "unprognostic (2.62e-2)" "unprognostic (1.14e-2)" "unprognostic (5.80e-2)" "unprognostic (5.10e-5)" "unprognostic (2.05e-2)" "unprognostic (1.14e-1)" "unprognostic (4.32e-2)" "unprognostic (3.55e-3)" "unprognostic (3.66e-1)" "prognostic unfavorable (7.08e-5)" "unprognostic (2.14e-1)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" "unprognostic (2.05e-3)" 3.1 6.6 8.7 2.9 13.1 4.8 3.6 10.0 11.9 3.2 2.3 3.2 2.4 3.1 2.6 5.1 3.0 2.0 3.5 8.5 10.4 3.5 1.8 3.1 4.6 10.7 11.3 3.7 3.1 2.9 6.4 3.4 12.1 5.1 2.1 2.1 5.2 2.9 4.9 12.5 4.2 2.8 7.4 5.1 4.3 2.3 12.4 5.2 3.9 2.5 4.5 4.8 4.4 21.0 3.7 2.7 23.9 3.9 5.7 2.5 7.6 3.4 9.9 6.3 5.5 3.0 3.7 5.9 3.8 3.0 3.2 7.2 5.0 4.3 5.6 5.8 3.8 6.5 3.2 2.5 5.7 2.2 16.2 5.2 3.9 8.7 2.0 9.9 6.3 5.0 1.1 3.8 6.1 9.9 6.8 2.0 6.0 4.3 3.5 8.6 12.8 2.7 3.8 9.6 6.0 3.7 3.8 14.5 16.8 12.6 4.1 1.4 6.3 2.7 3.8 8.1 2.8 6.9 3.3 2.7 5.1 3.9 3.5 1.2 1.0 3.4 1.3 1.8 2.3 1.1 1.9 1.8 0.9 1.4 1.3 1.2 2.3 1.0 1.1 0.4 4.7 1.1 8.7 13.1 10.0 11.9 8.5 10.4 10.7 11.3 12.1 7.4 12.4 21.0 2.0 3.2 2.2 2.6 1.8 2.7 0.8 1.7 2.8 3.4 3.5 1.9 0.9 0.0 1.2 1.8 0.0 1.1 2.5 1.5 0.0 1.4 0.5 0.6 1.1 1.4 1.8 0.4 1.9 1.9 1.8 2.1 4.1 1.3 1.3 1.7 1.1 0.7 1.2 10.1 10.2 1.5 4.1 1.2 1.6 0.5 2.5 1.3 0.0 10.3 1.4 1.5 3.1 50.8 26.0 2.6 0.6 4.9 2.6 2.1 1.2 1.0 0.4 1.0 6.6 2.0 2.1 1.3 0.6 2.8 4.7 1.4 3.0 3.4 0.9 2.0 TRIM65 ENSG00000141569 "Tripartite motif containing 65" Q6PJ69 17 75880335-75896951 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021575, HPA021578, HPA064820" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Vesicles, Cytosol" "HPA021575: AB_1858314, HPA021578: AB_1858315, HPA064820: AB_2685359" "unprognostic (1.82e-1)" "unprognostic (1.47e-1)" "unprognostic (3.47e-2)" "unprognostic (1.36e-1)" "unprognostic (1.96e-1)" "unprognostic (1.36e-2)" "prognostic unfavorable (4.74e-6)" "unprognostic (5.36e-2)" "unprognostic (8.71e-2)" "unprognostic (1.78e-1)" "unprognostic (5.82e-2)" "unprognostic (6.00e-3)" "prognostic unfavorable (1.82e-5)" "unprognostic (2.86e-3)" "unprognostic (7.18e-2)" "unprognostic (4.24e-3)" "unprognostic (7.50e-3)" 13.0 7.8 12.5 8.5 15.2 7.4 10.7 15.3 13.5 15.5 11.0 14.1 8.8 14.7 6.8 14.2 13.1 7.1 10.3 11.5 13.2 11.2 8.4 12.9 10.5 15.0 14.6 14.1 15.7 7.4 11.8 5.4 14.8 11.7 7.9 7.2 12.6 8.1 13.2 14.6 13.5 8.3 13.8 16.6 11.3 3.9 14.5 6.5 12.2 6.9 8.2 14.6 14.0 17.0 19.8 20.2 7.8 22.2 13.5 19.2 4.0 8.3 8.9 11.1 9.4 9.1 17.0 21.4 6.5 7.2 15.6 13.7 16.8 18.6 6.8 11.1 28.9 16.9 20.4 12.5 13.4 17.2 18.9 12.0 14.4 8.9 16.0 9.3 29.2 27.2 29.3 19.5 8.7 20.6 38.0 33.7 17.7 20.0 19.5 31.3 11.2 30.9 11.2 8.2 16.1 14.9 11.4 21.3 22.7 9.7 21.2 24.2 14.5 26.6 13.5 13.3 16.9 17.9 7.4 6.2 16.2 32.2 11.8 1.4 1.1 1.8 1.9 1.0 2.2 1.4 1.4 1.9 0.9 2.0 1.5 1.5 1.1 1.9 0.6 1.3 1.3 0.6 12.5 15.2 15.3 13.5 11.5 13.2 15.0 14.6 14.8 13.8 14.5 17.0 8.4 6.4 4.8 13.1 7.5 2.9 5.7 2.4 3.4 19.0 3.7 3.0 4.3 5.7 3.4 9.2 12.5 0.9 9.0 3.6 1.9 3.2 0.4 2.8 9.2 8.2 0.0 9.5 4.5 3.4 3.6 6.6 7.1 4.0 7.0 8.6 5.7 3.8 8.9 5.0 5.9 6.6 6.1 5.4 9.3 0.5 13.7 6.9 8.8 3.7 4.9 6.3 3.1 6.6 9.3 5.3 2.9 9.4 5.8 5.1 4.8 5.9 1.8 12.9 0.0 9.3 5.2 0.8 2.9 6.7 3.7 0.5 8.5 6.4 5.9 2.8 TRIM7 "GNIP, RNF90" ENSG00000146054 "Tripartite motif containing 7" Q9C029 5 181193924-181205293 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 193.3;tongue: 51.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 17.8;Cardiomyocytes: 40.1;Squamous epithelial cells: 39.6;Suprabasal keratinocytes: 28.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HaCaT: 16.4;HDLM-2: 35.0;PC-3: 18.8;TIME: 16.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA039213 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 35: T-regs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 37: Myocytes - Muscle contraction" Vesicles "Nucleoplasm, Cytosol" "HPA039213: AB_10795173" "unprognostic (6.58e-2)" "unprognostic (1.17e-1)" "unprognostic (5.20e-2)" "unprognostic (1.10e-2)" "unprognostic (6.85e-2)" "unprognostic (1.80e-2)" "unprognostic (3.89e-4)" "unprognostic (3.45e-2)" "unprognostic (3.72e-1)" "unprognostic (1.64e-1)" "unprognostic (3.48e-2)" "unprognostic (1.97e-1)" "unprognostic (7.16e-3)" "unprognostic (1.26e-1)" "unprognostic (3.90e-2)" "unprognostic (6.17e-2)" "unprognostic (1.15e-2)" 2.1 1.5 1.2 0.4 1.0 0.4 2.1 10.5 3.0 5.5 0.4 1.9 0.3 1.3 3.1 27.0 2.2 0.2 8.5 0.9 1.7 3.9 0.6 2.6 0.4 3.1 2.9 1.5 4.8 2.7 5.5 0.3 2.8 2.8 0.5 1.6 7.3 0.6 193.3 28.7 1.3 0.6 1.3 1.4 2.2 1.3 2.0 0.4 6.3 51.0 2.1 2.2 9.5 1.3 9.0 4.4 0.1 0.5 0.7 0.8 0.2 1.9 0.0 0.7 1.8 0.4 12.0 0.6 6.1 2.6 3.7 16.4 4.8 13.8 0.2 35.0 1.8 0.9 12.2 0.2 2.2 0.0 2.0 0.1 10.5 0.4 6.7 2.7 3.9 1.6 0.5 2.0 0.4 1.3 0.5 0.3 0.0 14.5 18.8 0.4 6.0 1.4 4.9 0.0 0.4 1.1 4.2 0.2 6.5 0.2 1.0 0.4 16.0 0.2 3.4 0.6 6.3 2.8 0.4 1.0 0.5 0.7 1.5 0.0 1.7 0.0 0.4 0.7 0.7 0.1 0.4 0.4 0.3 0.2 0.7 0.5 0.0 0.1 0.5 0.2 0.9 0.3 1.2 1.0 10.5 3.0 0.9 1.7 3.1 2.9 2.8 1.3 2.0 1.3 7.3 0.0 1.1 0.0 1.0 17.8 4.3 11.1 12.0 6.2 0.8 1.5 40.1 0.0 6.3 3.7 0.0 0.1 0.8 5.9 5.9 0.7 0.9 0.2 0.3 4.6 0.0 0.0 1.3 2.4 0.7 4.8 11.2 0.7 0.0 0.1 5.7 0.4 1.1 0.0 3.9 3.3 2.0 6.0 2.8 0.0 0.9 2.9 1.8 0.0 5.7 0.6 1.0 2.0 0.1 5.0 6.5 1.5 0.1 2.5 0.0 1.5 2.9 2.9 13.1 17.3 5.8 1.5 0.4 39.6 28.4 0.0 1.4 0.1 3.4 5.3 TRIM72 MG53 ENSG00000177238 "Tripartite motif containing 72" Q6ZMU5 16 31214091-31231537 "Predicted intracellular proteins, Transporters" "Exocytosis, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "skeletal muscle: 151.8;tongue: 43.0" "Cell type enriched" "Detected in many" 5 "Skeletal myocytes: 45.6" "Cancer enhanced" "Detected in some" "head and neck cancer: 0.9" "Region enriched" "Detected in many" 7 "cerebellum: 9.3" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HL-60: 7.2;LHCN-M2: 12.6;RH-30: 29.7;U-266/70: 17.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054909 Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" Vesicles Nucleoplasm "HPA054909: AB_2682639" "unprognostic (2.61e-1)" "unprognostic (3.21e-3)" "unprognostic (5.07e-2)" "unprognostic (9.77e-2)" "unprognostic (3.71e-1)" "unprognostic (3.13e-1)" "unprognostic (2.01e-3)" "unprognostic (2.80e-1)" "unprognostic (6.57e-2)" "unprognostic (4.90e-1)" "unprognostic (1.90e-1)" "unprognostic (2.49e-2)" "unprognostic (2.24e-10)" "unprognostic (7.70e-2)" "unprognostic (6.72e-2)" "unprognostic (4.15e-1)" "unprognostic (4.30e-4)" 0.2 0.2 0.9 0.2 0.8 0.8 0.2 9.3 1.0 0.1 0.5 0.2 0.2 0.2 0.3 1.0 0.1 0.2 0.8 0.7 0.4 0.1 0.1 0.2 0.3 1.0 0.5 0.2 0.3 0.1 0.0 0.2 1.3 1.9 0.1 0.8 2.5 0.1 151.8 0.5 0.2 0.1 0.1 0.3 0.3 0.3 0.5 0.1 0.2 43.0 0.2 0.1 0.0 1.2 0.1 0.1 0.2 0.4 0.2 0.1 0.3 0.3 0.1 0.0 0.0 0.2 0.4 0.2 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.3 0.1 0.2 0.7 0.2 0.2 7.2 0.3 1.2 0.1 0.0 0.1 0.1 0.0 0.2 0.3 0.8 12.6 0.1 0.1 0.5 0.2 0.2 0.2 0.3 29.7 4.1 0.0 0.2 2.6 0.2 0.1 0.3 0.1 0.3 0.2 2.6 0.1 0.2 0.2 0.2 0.1 17.9 1.7 0.2 0.2 0.4 0.2 1.9 0.3 0.5 0.3 0.3 0.3 0.4 0.3 0.2 0.3 0.6 0.4 0.3 1.5 0.6 0.4 0.6 0.2 0.1 0.9 0.8 9.3 1.0 0.7 0.4 1.0 0.5 1.3 0.1 0.5 1.2 4.7 3.2 3.8 0.0 0.8 0.1 3.1 0.0 0.0 1.0 3.1 8.0 3.0 0.0 2.5 0.0 2.1 0.3 2.4 0.0 0.0 0.0 0.3 1.5 4.7 1.5 0.0 0.0 0.2 0.0 0.3 2.5 0.0 4.0 1.3 0.8 0.4 0.0 0.2 0.0 0.1 0.2 0.0 1.2 0.3 0.0 0.0 3.1 0.0 0.0 0.6 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.3 1.9 0.1 0.1 0.0 0.9 0.0 45.6 2.2 0.1 0.2 0.8 0.3 0.1 2.2 1.2 0.9 1.5 TRIM8 "GERP, RNF27" ENSG00000171206 "Tripartite motif containing 8" Q9BZR9 10 102644479-102658318 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023560, HPA023561" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 38: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Vesicles, Cytosol" "HPA023560: AB_10600414, HPA023561: AB_10601861" "unprognostic (4.32e-2)" "unprognostic (6.90e-2)" "unprognostic (3.02e-3)" "unprognostic (1.45e-1)" "unprognostic (1.78e-1)" "unprognostic (5.03e-1)" "unprognostic (3.82e-2)" "unprognostic (1.03e-1)" "unprognostic (2.15e-3)" "unprognostic (4.62e-2)" "unprognostic (5.41e-2)" "unprognostic (1.52e-1)" "unprognostic (9.55e-2)" "unprognostic (1.48e-1)" "unprognostic (3.12e-2)" "unprognostic (8.34e-2)" "unprognostic (1.36e-2)" 80.1 47.6 67.2 21.5 68.1 26.0 58.4 62.9 55.0 63.0 35.8 50.9 17.8 53.5 9.3 42.0 55.6 22.0 67.8 55.0 56.5 77.9 62.2 70.3 18.3 72.4 72.7 45.2 80.4 36.6 43.5 21.3 64.7 55.5 9.5 18.1 69.1 21.9 80.8 48.3 43.8 17.1 60.4 42.8 61.9 20.1 84.4 18.7 67.4 38.8 11.8 62.9 49.9 54.2 96.4 18.7 16.3 28.7 17.2 40.6 21.1 34.4 59.3 32.1 24.6 30.7 93.0 30.7 102.9 57.5 11.4 32.7 12.2 40.4 21.3 34.4 23.4 78.3 12.9 67.4 55.8 15.5 28.3 47.0 21.9 64.8 32.9 83.4 40.6 13.6 17.3 33.4 24.3 45.5 27.8 57.7 12.7 25.6 38.0 18.6 49.2 16.6 37.4 48.0 12.3 26.2 18.8 17.2 42.6 16.9 58.4 28.2 94.8 40.9 22.4 23.3 68.8 49.0 28.5 16.3 65.5 39.2 9.7 14.0 5.2 2.7 6.8 4.6 6.5 8.9 7.3 5.4 4.5 7.4 6.4 5.7 17.9 6.0 5.7 12.4 7.5 4.5 67.2 68.1 62.9 55.0 55.0 56.5 72.4 72.7 64.7 60.4 84.4 54.2 46.0 57.7 71.2 33.6 29.5 31.5 12.6 21.2 21.6 33.4 53.9 45.3 38.0 38.6 33.6 88.3 8.4 13.0 52.8 15.4 41.1 63.2 1.1 91.5 61.7 30.1 21.6 2.5 8.9 44.9 2.6 38.9 20.4 81.6 8.8 32.2 31.8 33.3 25.4 28.6 13.6 32.8 18.3 40.5 24.1 1.7 31.1 43.5 17.8 13.1 58.1 26.1 24.7 18.1 17.6 65.0 16.4 34.3 18.6 30.5 32.0 53.0 38.5 15.1 13.1 35.7 38.4 2.4 5.1 19.8 22.9 10.9 26.6 38.9 21.4 30.1 TRIO ARHGEF23 ENSG00000038382 "Trio Rho guanine nucleotide exchange factor" O75962 5 14143342-14532128 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 205.7;Excitatory neurons: 400.9;Inhibitory neurons: 443.4;Microglial cells: 308.2;Oligodendrocyte precursor cells: 476.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 215.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008157, HPA064664" Supported Approved Vesicles,Cytosol No No "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol Vesicles "HPA008157: AB_1858327, HPA064664: AB_2685315" "unprognostic (6.65e-2)" "unprognostic (4.21e-3)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (9.39e-2)" "unprognostic (4.13e-1)" "unprognostic (2.18e-3)" "unprognostic (2.55e-1)" "unprognostic (7.52e-2)" "unprognostic (1.63e-1)" "unprognostic (2.02e-1)" "unprognostic (1.82e-1)" "prognostic unfavorable (3.11e-5)" "unprognostic (1.78e-2)" "unprognostic (1.96e-1)" "unprognostic (4.58e-3)" "unprognostic (2.23e-1)" 35.3 20.5 31.7 11.6 33.3 5.5 31.8 32.2 38.6 23.4 34.5 36.6 6.8 38.9 15.5 14.5 21.2 18.8 31.9 37.2 33.6 24.9 22.1 25.7 10.2 28.1 28.1 52.8 20.6 9.1 28.9 11.6 26.6 28.2 13.6 10.2 17.4 11.1 20.9 18.7 27.8 19.2 26.4 38.9 22.9 17.2 31.4 13.3 17.0 17.4 10.6 27.1 20.5 27.2 43.7 15.9 37.2 18.0 78.6 101.0 41.3 40.4 49.2 32.6 36.9 10.3 17.4 10.4 28.0 56.6 79.6 13.0 6.5 19.4 66.6 25.8 8.0 5.5 46.1 13.2 40.0 13.9 14.8 47.6 19.9 114.4 36.4 30.3 28.8 6.8 1.4 6.8 78.7 8.3 0.1 9.5 9.3 4.8 13.7 9.9 22.9 34.2 31.6 20.5 17.1 67.5 34.3 9.0 18.9 47.1 5.3 2.0 66.4 61.4 38.3 44.7 48.4 0.3 2.2 12.9 215.1 8.8 14.8 0.1 0.5 0.0 0.0 0.7 0.1 0.7 0.0 0.0 0.5 1.8 0.0 0.0 0.0 1.6 0.6 1.1 0.3 0.1 31.7 33.3 32.2 38.6 37.2 33.6 28.1 28.1 26.6 26.4 31.4 27.2 33.0 19.2 25.9 205.7 16.6 16.4 13.0 15.6 17.1 30.5 21.9 15.0 19.3 10.0 21.0 11.0 14.6 9.7 5.6 24.8 0.0 21.2 2.9 11.7 24.8 28.7 18.0 6.5 400.9 14.2 22.0 38.9 7.7 34.2 17.7 17.2 14.6 17.1 14.2 28.6 443.4 20.6 14.2 15.4 22.1 6.6 78.6 20.2 5.4 308.2 12.1 7.3 2.1 476.5 80.4 38.5 14.9 42.9 29.2 52.8 9.2 5.4 18.3 2.7 6.6 27.5 20.0 3.5 6.2 7.2 13.8 8.2 3.8 11.7 19.4 20.3 TRIP10 "CIP4, HSTP, STOT, STP" ENSG00000125733 "Thyroid hormone receptor interactor 10" Q15642 19 6737925-6751530 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 362.8" "Cell type enhanced" "Detected in many" "monocytes: 196.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "plasmacytoid DC: 26.4" "Lineage enriched" "Detected in many" 10 "dendritic cells: 26.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041934, HPA072625, HPA073886" Approved Supported Nucleoplasm,Vesicles NA NA 24000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 3: Monocytes - Immune response regulation" Vesicles Nucleoplasm "HPA041934: AB_2677754, HPA072625: AB_2732206, HPA073886: AB_2732244" "unprognostic (5.75e-2)" "unprognostic (1.98e-1)" "prognostic unfavorable (3.61e-4)" "unprognostic (2.19e-2)" "unprognostic (6.57e-2)" "prognostic favorable (1.76e-4)" "unprognostic (6.73e-3)" "unprognostic (1.10e-3)" "unprognostic (1.51e-1)" "unprognostic (3.41e-1)" "unprognostic (7.87e-3)" "unprognostic (3.28e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (1.14e-2)" "unprognostic (1.42e-1)" "unprognostic (8.93e-2)" "unprognostic (8.83e-2)" 110.7 60.3 15.5 25.5 15.6 8.6 92.3 15.3 17.8 123.9 18.6 112.1 30.5 66.5 17.5 253.3 80.1 27.6 125.7 14.6 16.7 81.7 27.0 115.4 14.5 17.5 16.5 99.4 44.7 18.6 22.4 48.6 16.0 80.4 19.9 16.9 85.4 45.0 362.8 57.8 56.0 26.4 15.8 40.0 58.6 29.9 17.5 9.6 75.5 177.3 21.9 86.7 147.4 14.8 83.5 49.7 17.1 25.8 64.7 67.9 61.1 52.5 60.0 58.8 51.1 67.8 46.7 1.8 69.2 44.6 47.6 60.2 38.8 76.5 34.7 52.5 15.5 27.0 48.4 52.3 53.4 1.4 8.3 79.0 50.9 52.5 39.8 77.2 61.2 3.7 40.2 22.1 43.7 28.3 7.5 18.7 36.3 51.9 41.7 12.2 35.1 24.5 50.0 40.9 0.1 19.6 69.1 30.7 20.0 39.4 32.2 14.7 120.5 39.3 70.4 103.8 56.4 23.1 13.4 8.4 63.6 7.9 26.2 0.0 0.8 0.0 0.6 0.1 0.9 1.5 0.3 1.1 5.2 1.7 0.3 0.2 0.1 2.5 0.1 26.4 0.0 0.5 15.5 15.6 15.3 17.8 14.6 16.7 17.5 16.5 16.0 15.8 17.5 14.8 43.0 28.9 19.8 6.5 5.6 85.4 104.9 76.9 43.9 14.7 28.3 16.6 8.7 20.0 66.9 16.5 37.5 9.9 16.5 39.1 5.9 45.0 16.4 30.3 32.1 43.1 7.7 4.4 0.1 38.0 37.9 66.3 10.7 55.7 29.7 8.8 38.9 3.7 9.6 0.0 0.2 16.3 24.4 6.7 90.4 13.6 55.9 19.6 37.4 3.7 196.9 12.5 0.0 5.5 0.4 91.5 24.7 36.1 9.0 116.6 25.8 23.8 24.8 18.5 32.9 26.4 46.4 5.7 6.9 51.3 83.3 14.2 7.4 24.5 25.9 120.7 TRO "KIAA1114, MAGE-D3, MAGED3" ENSG00000067445 Trophinin Q12816 X 54920462-54931431 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 31.1" "Cell type enhanced" "Detected in many" "Astrocytes: 9.4;Excitatory neurons: 14.6;Granulosa cells: 12.3;Inhibitory neurons: 20.0;Oligodendrocyte precursor cells: 17.1;Oligodendrocytes: 9.4" "Cancer enhanced" "Detected in many" "testis cancer: 11.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "NK-cell: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 37.1;SH-SY5Y: 33.8;SuSa: 74.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071449 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "Plasma membrane, Cytosol" "HPA071449: " "unprognostic (6.18e-2)" "unprognostic (1.01e-1)" "unprognostic (2.24e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (9.09e-3)" "unprognostic (2.72e-1)" "unprognostic (5.66e-2)" "unprognostic (1.46e-1)" "unprognostic (4.67e-2)" "unprognostic (3.18e-1)" "prognostic favorable (1.93e-4)" "unprognostic (1.17e-1)" "unprognostic (3.19e-2)" "unprognostic (1.67e-4)" "unprognostic (6.33e-2)" "unprognostic (3.27e-2)" "unprognostic (6.86e-2)" 3.9 3.0 13.9 1.3 10.6 1.0 3.7 0.8 23.7 9.5 0.9 3.2 0.9 13.4 6.6 1.6 5.3 4.2 2.4 9.3 17.2 3.9 16.8 2.1 1.6 6.2 5.1 17.5 7.1 5.3 24.4 4.3 6.9 5.5 2.1 6.2 1.5 5.2 31.1 1.2 1.6 8.6 3.4 1.0 2.0 2.6 12.6 4.7 10.1 1.0 1.6 2.5 5.5 13.3 0.0 0.3 37.1 0.1 7.1 9.8 0.0 2.1 13.1 2.0 0.7 0.0 0.0 0.0 5.3 13.8 3.1 0.2 0.3 0.6 1.0 0.1 23.3 18.0 0.0 1.5 2.7 0.0 0.1 22.8 0.0 12.0 0.0 11.8 0.9 9.1 0.0 0.2 14.0 0.0 0.3 0.1 19.6 0.1 0.0 11.3 16.4 0.1 3.5 0.3 25.3 33.8 0.0 0.5 3.1 74.2 0.0 2.2 0.0 15.7 15.9 0.2 2.2 5.8 0.9 0.0 2.3 0.0 13.8 0.0 0.0 0.0 0.4 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.1 0.2 0.0 2.2 0.1 0.9 0.0 0.1 13.9 10.6 0.8 23.7 9.3 17.2 6.2 5.1 6.9 3.4 12.6 13.3 0.4 0.0 0.0 9.4 0.3 0.4 1.4 0.8 5.2 4.2 0.5 1.9 1.8 0.0 1.9 3.7 0.0 0.8 0.2 0.0 0.0 1.7 0.4 0.3 7.9 1.9 0.0 0.0 14.6 0.2 0.6 7.0 0.5 0.5 1.3 12.3 0.4 0.0 0.5 8.4 20.0 0.0 0.0 0.0 0.4 0.6 5.9 0.2 0.0 1.0 0.1 2.2 0.0 17.1 9.4 0.2 0.0 3.8 0.1 0.4 0.0 0.4 0.0 0.9 0.0 1.5 3.3 1.2 1.9 0.1 0.1 0.7 0.7 2.9 0.0 0.3 TRPC1 HTRP-1 ENSG00000144935 "Transient receptor potential cation channel subfamily C member 1" P48995 3 142724034-142807888 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Astrocytes: 93.7;Excitatory neurons: 144.6;Granulosa cells: 91.8;Inhibitory neurons: 184.4;Microglial cells: 49.6;Oligodendrocyte precursor cells: 154.8;Oligodendrocytes: 164.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 23.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009387, HPA021130" Supported Approved Vesicles NA NA "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Vesicles "CAB009387: AB_2240941, HPA021130: AB_1858361" "unprognostic (1.66e-1)" "unprognostic (7.38e-2)" "unprognostic (1.56e-2)" "unprognostic (4.37e-5)" "unprognostic (5.53e-1)" "unprognostic (1.40e-2)" "unprognostic (5.90e-3)" "unprognostic (1.59e-2)" "unprognostic (1.36e-1)" "unprognostic (2.17e-1)" "unprognostic (8.46e-3)" "unprognostic (6.25e-2)" "prognostic unfavorable (2.72e-5)" "unprognostic (1.44e-3)" "unprognostic (1.57e-1)" "unprognostic (1.61e-1)" "unprognostic (2.49e-2)" 5.2 4.7 7.3 1.9 7.9 0.3 4.7 10.9 7.5 9.1 5.8 7.6 1.2 11.1 5.2 3.6 8.6 5.4 10.1 7.9 7.0 3.2 0.8 3.3 1.9 7.1 5.6 14.2 1.4 6.5 10.3 3.5 7.7 7.0 2.5 22.8 2.9 7.8 1.2 3.6 3.9 10.6 6.1 2.8 3.2 4.8 6.1 1.5 5.1 3.6 1.0 6.3 6.9 7.9 4.2 5.7 10.8 1.2 9.7 23.9 4.8 6.8 10.5 8.4 12.2 1.7 1.1 0.0 2.1 7.0 14.2 0.3 3.0 3.2 12.2 1.0 4.1 6.8 2.6 2.9 4.0 0.4 0.0 11.4 3.2 7.9 9.4 14.2 4.9 0.0 0.2 0.0 12.1 2.6 0.4 0.5 6.0 0.1 3.1 0.0 5.0 0.0 5.9 0.1 6.7 4.8 8.1 0.0 1.5 9.9 3.3 0.1 4.3 10.1 1.6 14.0 9.1 3.9 1.8 2.1 7.7 0.1 3.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.3 7.9 10.9 7.5 7.9 7.0 7.1 5.6 7.7 6.1 6.1 7.9 6.2 3.2 0.5 93.7 2.9 2.9 1.6 1.2 7.4 17.9 0.9 1.8 12.0 1.5 0.6 5.5 16.7 0.2 0.3 0.0 0.0 0.3 3.6 0.5 10.8 4.6 1.8 0.4 144.6 0.2 0.2 13.2 0.0 0.9 0.0 91.8 3.6 0.0 0.1 13.5 184.4 0.0 0.0 0.0 1.6 2.9 8.4 0.5 1.8 49.6 0.1 7.7 0.0 154.8 164.8 0.1 0.0 10.9 1.5 0.9 0.0 0.7 3.0 16.0 0.0 10.4 12.0 9.8 2.8 0.7 1.1 0.3 2.2 1.7 0.0 0.3 TRPM3 "GON-2, KIAA1616, LTRPC3" ENSG00000083067 "Transient receptor potential cation channel subfamily M member 3" Q9HCF6 9 70529060-71446904 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "choroid plexus: 801.0" "Cell type enhanced" "Detected in many" "Astrocytes: 905.0;Excitatory neurons: 390.3;Inhibitory neurons: 186.9;Muller glia cells: 184.5" "Cancer enhanced" "Detected in single" "renal cancer: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "HAP1: 17.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA072650, HPA074393" Enhanced Approved Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA072650: , HPA074393: " "unprognostic (3.74e-1)" "unprognostic (6.30e-2)" "unprognostic (4.79e-2)" "unprognostic (4.81e-2)" "unprognostic (1.38e-2)" "unprognostic (8.88e-2)" "unprognostic (1.49e-2)" "unprognostic (2.19e-2)" "unprognostic (1.11e-1)" "unprognostic (1.89e-2)" "unprognostic (6.10e-2)" "unprognostic (1.15e-2)" "unprognostic (1.82e-7)" "unprognostic (3.51e-2)" "unprognostic (5.64e-2)" "unprognostic (1.74e-2)" "unprognostic (1.50e-2)" 0.7 0.6 22.0 0.1 30.4 0.2 0.1 40.5 9.6 1.0 801.0 0.2 0.8 1.1 1.3 0.1 0.4 0.4 0.8 39.3 27.8 16.5 0.2 0.1 0.1 36.7 46.8 3.6 0.5 0.0 2.9 0.1 20.8 0.5 0.1 23.0 0.1 2.5 0.3 0.1 0.0 0.2 25.2 0.3 0.6 5.1 41.6 0.2 0.9 0.1 0.0 0.1 0.4 15.4 0.0 0.0 0.9 0.0 1.1 2.6 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 17.2 0.0 0.1 0.0 0.1 0.1 1.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 2.3 0.2 0.0 0.0 1.0 4.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.2 0.0 0.9 0.0 1.1 0.0 0.2 0.0 0.3 0.2 0.0 0.0 3.1 0.0 0.1 3.1 0.0 0.0 0.0 0.0 0.4 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 22.0 30.4 40.5 9.6 39.3 27.8 36.7 46.8 20.8 25.2 41.6 15.4 0.3 3.2 3.0 905.0 0.5 0.4 0.9 0.0 0.6 16.4 0.3 0.5 5.3 5.7 2.5 16.5 66.7 0.1 0.2 0.1 5.9 0.1 4.8 1.4 1.0 1.3 15.4 0.0 390.3 0.2 0.1 3.0 0.0 3.2 0.0 1.4 0.7 0.3 0.2 1.7 186.9 0.1 0.0 0.9 1.4 2.3 5.6 0.8 0.0 56.2 0.2 184.5 1.0 105.6 8.3 0.1 0.1 9.1 0.0 0.5 0.1 33.3 0.8 10.1 0.0 3.5 1.3 1.3 0.6 0.0 0.9 0.3 0.9 0.6 0.0 0.3 TRPM7 "CHAK1, LTRPC7, TRP-PLIK" ENSG00000092439 "Transient receptor potential cation channel subfamily M member 7" Q96QT4 15 50552473-50686797 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Necrosis, Transport" "Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase" "Amyotrophic lateral sclerosis, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 108.9" "Cell type enhanced" "Detected in all" "Excitatory neurons: 122.2;Oligodendrocytes: 109.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 122.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035522, HPA052173" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Vesicles, Cytosol" "HPA035522: , HPA052173: AB_2681749" "unprognostic (3.14e-2)" "unprognostic (1.86e-1)" "unprognostic (1.58e-1)" "unprognostic (1.42e-2)" "unprognostic (1.89e-1)" "unprognostic (1.60e-2)" "unprognostic (1.85e-2)" "unprognostic (2.59e-2)" "unprognostic (5.46e-3)" "unprognostic (2.64e-1)" "unprognostic (2.91e-1)" "unprognostic (1.59e-2)" "unprognostic (3.20e-2)" "unprognostic (2.08e-1)" "unprognostic (7.59e-2)" "unprognostic (9.45e-2)" "unprognostic (1.97e-1)" 11.5 9.6 4.3 13.3 6.5 21.4 13.6 15.4 6.7 10.3 29.3 13.8 14.4 12.7 14.6 8.6 9.4 11.1 15.5 4.8 3.5 22.9 25.3 11.6 16.6 4.9 3.9 16.4 12.2 108.9 5.3 13.3 5.9 10.9 14.4 10.5 10.9 10.6 7.8 16.6 13.1 11.4 3.2 12.2 13.6 9.9 6.4 15.5 17.3 9.1 14.4 11.4 8.1 10.4 21.4 21.0 17.2 19.1 48.5 36.2 20.9 26.4 36.7 16.5 21.6 29.1 11.6 46.4 12.7 30.8 42.5 35.1 23.3 19.5 23.4 26.0 13.7 37.1 31.5 15.4 44.0 38.8 27.6 33.9 22.4 18.8 35.0 24.0 13.5 28.8 42.6 34.5 30.4 33.7 25.1 18.8 13.0 29.4 12.8 27.2 23.7 22.7 23.0 49.9 14.2 18.1 18.2 28.7 35.8 30.1 18.0 41.6 20.7 26.1 12.4 122.4 30.8 23.3 54.9 44.0 28.4 77.5 24.8 1.8 1.3 1.6 2.5 1.3 2.9 2.2 1.8 1.7 1.5 2.3 1.6 1.9 1.7 2.4 1.4 1.9 2.0 0.8 4.3 6.5 15.4 6.7 4.8 3.5 4.9 3.9 5.9 3.2 6.4 10.4 23.9 19.2 31.3 73.1 36.4 31.6 17.2 11.0 44.9 21.9 18.8 11.9 25.9 21.5 8.2 12.9 12.5 23.0 38.4 17.0 3.9 11.7 33.3 21.6 27.1 19.7 18.5 29.6 122.2 12.7 9.4 26.1 37.8 23.1 17.7 26.0 14.6 43.9 14.6 21.9 92.7 19.5 6.1 22.4 19.8 26.0 26.4 26.5 19.6 66.5 24.2 8.5 29.9 80.9 109.1 15.5 13.9 20.3 33.2 24.9 23.4 11.0 19.3 22.6 13.1 30.0 22.0 23.1 23.6 25.7 24.2 16.3 34.5 22.2 20.4 11.1 TRUB1 PUS4 ENSG00000165832 "TruB pseudouridine synthase family member 1" Q8WWH5 10 114938195-114977676 "Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 62.2;Theca cells: 74.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037914, HPA057552" Approved Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 1: Thyroid gland - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA037914: AB_10672399, HPA057552: AB_2683465" "unprognostic (1.98e-1)" "unprognostic (1.91e-2)" "unprognostic (1.27e-2)" "unprognostic (2.93e-2)" "unprognostic (3.20e-3)" "unprognostic (9.79e-2)" "unprognostic (9.26e-2)" "unprognostic (4.89e-2)" "unprognostic (6.87e-2)" "unprognostic (2.51e-2)" "unprognostic (2.26e-2)" "unprognostic (1.56e-1)" "unprognostic (1.50e-3)" "unprognostic (7.54e-2)" "unprognostic (2.12e-1)" "unprognostic (1.25e-1)" "unprognostic (1.09e-1)" 7.4 29.3 6.3 7.5 7.4 4.2 11.3 5.1 9.0 9.8 7.3 9.5 8.9 12.8 9.3 8.3 9.7 7.7 21.5 7.6 7.1 16.0 12.9 6.6 10.0 5.8 6.0 16.8 6.8 15.8 4.9 7.5 6.1 11.7 10.4 6.7 9.3 9.9 7.5 6.5 8.2 11.1 5.6 9.3 8.7 17.9 7.0 11.5 12.3 9.7 10.1 7.8 4.8 6.4 25.5 19.6 18.8 47.0 13.3 17.7 25.3 21.4 24.1 28.4 32.0 16.1 25.5 31.4 24.2 16.9 12.4 21.3 25.6 26.5 41.8 23.9 27.5 14.4 9.2 28.8 22.8 27.2 20.7 18.2 35.8 20.2 39.6 30.1 16.2 24.9 15.1 12.5 34.1 12.3 25.7 21.6 17.8 17.0 19.1 25.4 47.5 19.2 37.4 12.7 17.5 19.3 18.0 26.4 47.7 20.0 21.1 16.6 14.5 13.0 13.0 20.8 26.5 23.6 20.4 26.3 18.3 34.2 11.9 4.0 2.6 0.9 4.4 4.0 6.5 7.3 4.7 4.7 4.8 5.9 6.2 5.8 0.2 8.1 7.3 4.3 6.2 4.6 6.3 7.4 5.1 9.0 7.6 7.1 5.8 6.0 6.1 5.6 7.0 6.4 6.9 12.8 8.4 8.8 11.2 5.6 4.7 15.3 6.2 13.9 11.9 8.1 13.6 4.3 12.0 9.2 2.1 9.1 10.5 7.1 21.5 7.6 62.2 11.1 12.8 6.6 7.7 9.0 23.0 4.9 6.6 11.2 6.6 12.0 10.2 26.7 12.1 20.2 7.6 25.2 22.0 8.2 6.1 7.3 4.2 9.6 8.4 5.0 3.6 8.4 5.4 10.4 9.2 31.2 16.7 7.0 3.6 10.1 12.7 4.2 6.2 27.9 9.8 5.6 6.6 8.4 9.3 14.5 23.3 15.9 7.0 6.2 8.0 74.1 12.9 5.8 TSGA13 ENSG00000213265 "Testis specific 13" Q96PP4 7 130668643-130687432 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 103 "testis: 14.0" "Group enriched" "Detected in some" 18 "Early spermatids: 86.4;Late spermatids: 224.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA022968 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "Plasma membrane, Cytosol" "HPA022968: AB_2671013" "unprognostic (1.49e-1)" "unprognostic (1.13e-2)" "unprognostic (1.86e-1)" "unprognostic (1.34e-1)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 3.2 3.9 0.0 0.3 1.7 0.1 0.0 0.0 1.2 0.3 0.1 0.1 0.0 1.9 0.0 8.4 0.1 0.3 0.0 0.0 0.0 86.4 0.3 0.3 1.0 0.0 0.0 0.2 0.0 0.0 2.0 0.0 0.4 0.0 0.4 0.7 0.0 0.1 0.0 0.2 0.0 0.0 0.9 2.2 224.1 0.6 0.8 0.0 0.0 0.1 0.6 1.0 0.5 0.1 0.0 0.0 0.7 0.3 0.0 0.0 0.0 6.0 1.5 0.0 0.0 0.3 1.6 0.6 0.0 0.4 0.7 0.6 0.1 0.0 0.0 TSLP ENSG00000145777 "Thymic stromal lymphopoietin" Q969D9 5 111070062-111078026 "Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 11.5;urinary bladder: 12.0" "Group enriched" "Detected in many" 4 "Basal respiratory cells: 108.1;Basal squamous epithelial cells: 338.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 15.0;HHSteC: 17.1;hTCEpi: 10.3;hTEC/SVTERT24-B: 18.9;hTERT-HME1: 12.5;hTERT-RPE1: 38.6;U-87 MG: 14.1" "Not detected" "Not detected" HPA056350 Uncertain "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 38400 "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus, Vesicles" "HPA056350: " "unprognostic (6.47e-4)" "unprognostic (3.26e-1)" "unprognostic (6.57e-2)" "unprognostic (1.93e-1)" "unprognostic (5.03e-2)" "unprognostic (7.72e-2)" "unprognostic (1.21e-1)" "unprognostic (2.53e-2)" "unprognostic (5.81e-2)" "unprognostic (1.24e-1)" "unprognostic (6.15e-2)" "unprognostic (4.24e-1)" "unprognostic (1.88e-1)" "unprognostic (5.04e-2)" "unprognostic (1.95e-1)" "unprognostic (2.76e-1)" "unprognostic (1.74e-3)" 1.6 0.7 0.3 1.3 0.3 0.0 1.5 0.3 0.5 1.4 0.2 1.1 0.7 0.8 0.3 3.8 0.6 8.8 4.3 0.3 0.3 1.2 11.5 1.9 0.4 0.4 0.3 0.3 0.3 0.4 0.4 0.1 0.4 6.2 0.9 0.0 1.2 4.0 1.4 0.8 1.0 0.6 0.3 0.4 1.2 4.8 1.1 0.2 2.7 1.4 0.5 12.0 1.9 0.4 0.0 0.0 0.0 1.8 2.3 15.0 0.0 0.0 2.3 0.4 2.6 0.0 0.0 0.0 0.1 0.0 0.5 0.0 1.5 0.5 0.8 0.0 2.4 2.8 0.1 0.0 17.1 0.5 0.0 0.3 10.3 18.9 12.5 38.6 0.0 6.6 0.3 0.0 3.2 0.0 2.5 0.0 0.4 0.1 0.0 0.0 1.1 0.0 0.0 0.1 0.1 2.2 0.0 0.0 0.0 1.2 0.0 1.1 0.0 0.0 0.9 0.0 0.0 4.1 0.0 0.0 14.1 0.3 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.5 0.3 0.3 0.4 0.3 0.4 0.3 1.1 0.4 6.2 0.0 3.1 0.3 0.1 55.8 26.6 108.1 338.6 0.0 6.5 8.0 7.4 0.0 35.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 38.5 0.1 0.9 10.5 0.0 0.0 0.0 0.0 0.1 10.0 0.0 0.1 0.0 0.9 7.9 9.4 0.2 0.0 0.0 0.0 24.4 1.2 5.0 26.3 0.6 0.8 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.8 24.7 0.2 1.6 3.5 0.0 0.0 6.9 3.8 0.4 0.9 38.0 25.1 0.0 0.8 1.9 0.1 3.1 TSPAN1 "NET-1, TSPAN-1" ENSG00000117472 "Tetraspanin 1" O60635 1 46175073-46185962 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 593.8;kidney: 244.3" "Cell type enhanced" "Detected in many" "Club cells: 723.5;Distal enterocytes: 1983.8;Late spermatids: 838.1;Paneth cells: 1127.7;Respiratory ciliated cells: 1817.6" "Cancer enhanced" "Detected in all" "prostate cancer: 455.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 57 "plasmacytoid DC: 5.6" "Lineage enriched" "Detected in single" 57 "dendritic cells: 5.6" "Cell line enhanced" "Detected in many" "A-431: 129.6;CAPAN-2: 216.7;HaCaT: 151.4;hTCEpi: 173.6;OE19: 257.9;RPTEC TERT1: 628.4;RT4: 308.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA011909 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles" "HPA011909: AB_2668565" "unprognostic (1.21e-1)" "unprognostic (3.11e-1)" "unprognostic (3.67e-2)" "unprognostic (4.12e-1)" "unprognostic (2.69e-2)" "unprognostic (1.35e-1)" "unprognostic (4.41e-2)" "unprognostic (4.68e-2)" "unprognostic (2.52e-2)" "unprognostic (1.44e-1)" "unprognostic (1.88e-3)" "unprognostic (8.73e-2)" "prognostic favorable (9.28e-6)" "unprognostic (5.90e-2)" "unprognostic (2.61e-1)" "unprognostic (4.90e-2)" "unprognostic (4.30e-2)" 1.9 4.3 0.5 53.2 0.7 0.0 6.2 1.7 1.1 78.2 1.4 523.3 25.4 17.7 34.7 5.5 122.4 28.9 0.9 0.5 0.5 244.3 3.9 32.1 0.4 1.2 0.6 0.4 3.1 72.0 17.3 1.1 1.1 194.7 593.8 0.0 101.0 65.9 0.8 2.5 96.7 20.8 1.0 0.7 213.1 27.3 0.6 1.9 121.9 0.1 4.9 104.9 9.9 1.8 129.6 2.0 0.0 0.0 0.2 0.0 1.8 0.1 2.7 0.1 0.0 0.0 216.7 0.0 40.2 0.3 0.2 151.4 0.0 111.2 0.1 0.0 0.0 0.0 1.1 7.6 0.0 0.0 0.2 0.0 173.6 0.7 60.9 3.6 0.3 1.3 0.0 0.0 1.6 4.9 0.0 0.5 0.1 257.9 8.1 0.1 0.1 1.6 628.4 308.2 1.9 0.0 0.3 13.0 0.5 0.5 9.0 0.1 1.4 0.0 0.7 0.4 0.7 1.5 0.1 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.5 0.7 1.7 1.1 0.5 0.5 1.2 0.6 1.1 1.0 0.6 1.8 2.5 25.6 29.5 0.3 7.4 1.0 194.4 499.9 4.0 0.0 14.5 11.0 0.7 11.5 723.5 579.4 0.0 0.3 0.2 1983.8 46.9 61.3 141.3 268.3 14.1 4.5 201.8 0.0 1.2 525.1 0.1 6.0 223.3 144.3 11.4 0.0 1.4 3.6 0.3 0.0 1.3 648.1 242.1 0.3 0.3 838.1 5.0 5.3 5.4 1.0 1.6 0.0 0.0 0.5 1.6 484.4 1127.7 1.9 0.7 211.7 505.4 477.8 1817.6 0.0 0.0 0.4 54.1 4.7 2.6 2.9 1.3 0.0 7.4 0.0 275.9 517.0 TSPAN11 ENSG00000110900 "Tetraspanin 11" A1L157 12 30926428-30996602 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "intestine: 25.9" "Cell type enhanced" "Detected in some" "Hepatic stellate cells: 5.7;Inhibitory neurons: 5.7;Late spermatids: 10.6;Oligodendrocyte precursor cells: 27.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 25.2;HSkMC: 22.8;NTERA-2: 18.2;SCLC-21H: 9.7;SH-SY5Y: 18.6;SuSa: 11.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066789 Approved Vesicles NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "HPA066789: AB_2685723" "unprognostic (4.10e-2)" "unprognostic (4.27e-2)" "unprognostic (4.38e-3)" "unprognostic (1.18e-2)" "unprognostic (4.51e-1)" "prognostic favorable (5.28e-4)" "unprognostic (4.28e-2)" "prognostic favorable (3.43e-4)" "unprognostic (7.89e-3)" "unprognostic (8.05e-2)" "unprognostic (1.51e-2)" "unprognostic (3.03e-2)" "unprognostic (5.77e-3)" "unprognostic (2.04e-2)" "unprognostic (5.81e-2)" "unprognostic (2.90e-3)" "unprognostic (1.79e-1)" 2.5 2.1 5.5 7.5 5.1 0.0 1.9 9.3 5.0 6.5 0.8 25.9 3.9 1.7 5.8 3.5 1.9 7.1 6.5 5.0 3.9 1.0 0.7 3.4 2.2 4.5 5.7 0.8 1.1 0.1 1.0 0.7 3.7 4.1 8.8 1.4 2.4 4.8 0.4 5.6 9.6 6.4 2.3 2.4 3.8 1.0 6.3 0.8 3.1 1.2 4.1 4.5 3.6 4.8 0.0 0.3 25.2 0.0 0.1 0.3 0.2 0.3 0.8 0.0 0.0 0.0 0.8 0.0 1.4 2.2 0.1 0.6 0.3 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.0 0.1 22.8 0.1 0.1 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.2 0.0 0.0 18.2 0.0 0.2 0.1 0.1 0.5 0.0 0.1 9.7 18.6 0.2 0.0 0.1 11.2 0.0 0.0 0.0 0.1 1.2 0.2 0.0 0.1 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.1 9.3 5.0 5.0 3.9 4.5 5.7 3.7 2.3 6.3 4.8 0.6 0.0 0.0 3.6 0.0 0.8 0.0 0.0 0.0 1.7 0.1 0.0 2.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 1.5 2.4 3.3 0.0 0.0 1.5 0.0 0.0 4.3 0.0 0.4 0.0 0.2 5.7 0.2 0.1 0.0 5.7 0.0 0.0 0.0 1.7 10.6 4.7 0.2 1.8 1.0 0.0 3.6 0.0 27.2 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.9 0.5 0.0 0.3 1.1 0.2 0.5 0.1 1.1 0.0 0.2 0.1 0.0 0.1 TSPAN12 "NET-2, TM4SF12" ENSG00000106025 "Tetraspanin 12" O95859 7 120787320-120858402 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 91.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 118.6;Collecting duct cells: 103.0;Distal tubular cells: 189.8;Glandular and luminal cells: 87.5;Proximal tubular cells: 111.1" "Cancer enhanced" "Detected in all" "renal cancer: 44.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 53.0;HUVEC TERT2: 58.3;RH-30: 52.2;RPTEC TERT1: 90.5;RT4: 65.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051570, HPA058244" Uncertain Approved Vesicles,Microtubules NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" Microtubules Vesicles "HPA051570: , HPA058244: AB_2683652" "unprognostic (2.40e-2)" "unprognostic (7.60e-2)" "unprognostic (3.66e-3)" "unprognostic (1.82e-2)" "unprognostic (3.97e-1)" "unprognostic (7.34e-3)" "unprognostic (1.60e-1)" "unprognostic (8.12e-2)" "unprognostic (1.23e-1)" "unprognostic (2.73e-1)" "unprognostic (1.63e-2)" "unprognostic (1.05e-1)" "unprognostic (9.53e-2)" "unprognostic (7.07e-2)" "unprognostic (1.51e-1)" "unprognostic (5.18e-2)" "unprognostic (1.43e-1)" 11.9 65.9 4.1 5.3 4.4 0.4 8.7 5.2 5.2 21.4 2.8 24.0 39.4 10.5 14.9 5.0 10.9 20.4 47.7 3.3 4.7 91.6 35.8 45.8 4.5 8.0 6.2 1.7 17.4 10.7 7.5 20.3 5.2 6.8 20.4 1.8 46.8 22.4 3.3 1.6 42.0 11.9 4.6 28.2 22.1 3.9 8.1 2.7 23.4 5.5 4.3 17.5 4.0 3.6 0.0 1.4 15.1 0.2 3.1 1.0 14.7 0.3 0.6 1.2 5.0 2.5 4.0 0.0 10.4 0.4 1.8 0.2 7.7 1.6 1.9 0.0 53.0 2.8 14.5 2.2 8.1 0.1 2.5 0.3 0.0 0.4 0.3 2.1 58.3 0.0 0.7 1.8 6.8 2.0 0.2 0.4 24.5 11.1 9.4 0.1 52.2 2.0 90.5 65.4 12.5 7.4 0.7 1.3 0.0 20.0 8.0 1.9 2.5 12.3 3.8 0.1 6.5 15.8 0.0 0.2 1.7 0.0 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 4.4 5.2 5.2 3.3 4.7 8.0 6.2 5.2 4.6 8.1 3.6 40.0 118.6 45.0 18.6 1.7 2.5 20.3 1.8 14.8 0.0 19.4 3.8 62.5 64.3 19.9 103.0 0.0 40.5 0.0 18.0 189.8 6.8 0.6 63.4 9.0 38.0 9.6 2.7 1.8 7.2 53.5 10.0 14.8 87.5 2.5 1.8 18.2 32.9 4.1 0.0 2.9 16.9 6.1 0.8 3.6 1.5 4.1 1.5 5.4 3.7 0.0 0.5 0.0 10.1 0.4 4.7 30.5 0.7 2.2 9.1 68.3 111.1 5.7 0.1 0.0 11.6 16.6 0.6 8.9 13.8 2.0 24.2 1.9 9.6 35.5 28.3 TSPAN14 "DC-TM4F2, MGC11352, TM4SF14" ENSG00000108219 "Tetraspanin 14" Q8NG11 10 80454166-80533124 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatic stellate cells: 156.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "TIME: 276.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014773, HPA057174" Uncertain Supported Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA014773: AB_2208670, HPA057174: " "unprognostic (7.52e-2)" "prognostic favorable (3.56e-4)" "unprognostic (6.55e-3)" "unprognostic (1.56e-1)" "unprognostic (4.40e-2)" "unprognostic (1.18e-1)" "unprognostic (2.11e-2)" "unprognostic (8.90e-2)" "unprognostic (5.21e-2)" "unprognostic (3.13e-1)" "unprognostic (5.15e-3)" "unprognostic (4.12e-3)" "prognostic favorable (4.20e-4)" "unprognostic (2.52e-2)" "unprognostic (1.53e-1)" "unprognostic (2.99e-1)" "unprognostic (2.57e-3)" 97.9 20.7 29.1 43.1 24.2 57.2 80.1 25.1 29.7 63.1 19.4 33.4 30.9 38.4 44.1 92.1 47.1 32.9 51.2 26.2 21.4 45.7 21.1 70.8 54.2 31.7 32.2 47.2 33.1 35.7 15.7 81.9 29.7 34.8 27.1 7.9 47.7 34.1 24.9 74.3 34.8 33.3 31.2 48.5 24.7 23.2 32.8 40.1 46.5 42.1 44.6 55.0 56.1 31.4 96.2 135.6 128.3 44.5 186.6 59.3 59.6 49.3 91.8 51.1 38.0 134.8 54.6 31.5 93.2 26.4 18.9 97.0 35.9 88.5 41.4 55.9 13.9 88.9 15.8 118.2 63.5 31.8 20.3 58.8 77.2 52.8 92.1 94.8 191.5 31.8 48.8 23.0 15.0 83.3 50.0 23.3 29.5 61.2 0.1 167.9 14.9 5.3 203.9 131.9 27.5 42.3 19.7 133.7 149.5 43.7 54.1 79.8 276.3 13.0 52.8 12.4 35.1 10.7 42.0 11.8 42.2 65.4 57.5 16.2 51.5 56.3 92.1 102.1 41.3 13.8 70.7 81.1 33.9 13.7 82.3 79.3 54.7 95.2 172.8 13.6 61.8 84.3 29.1 24.2 25.1 29.7 26.2 21.4 31.7 32.2 29.7 31.2 32.8 31.4 141.9 16.0 55.1 13.1 18.5 34.9 40.3 54.6 35.3 2.1 29.5 23.2 11.3 25.8 39.0 33.1 77.2 7.8 38.4 32.8 7.9 43.8 2.4 44.7 38.9 95.3 64.2 35.6 12.9 24.8 74.4 18.8 18.3 75.1 7.6 41.2 156.7 21.1 50.5 3.3 7.4 37.0 34.6 129.3 12.9 4.1 39.1 66.5 14.2 35.6 51.8 23.7 89.6 4.5 13.5 64.2 21.6 41.0 18.4 55.7 23.4 8.0 29.6 7.1 98.6 10.2 43.1 5.0 19.0 80.2 36.4 7.7 55.7 10.4 30.6 69.7 TSPAN15 "NET-7, TM4SF15" ENSG00000099282 "Tetraspanin 15" O95858 10 69451465-69507666 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 125.8;Ductal cells: 125.2;Exocrine glandular cells: 189.3;Pancreatic endocrine cells: 193.4;Paneth cells: 120.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "MAIT T-cell: 19.5" "Lineage enriched" "Detected in many" 6 "T-cells: 19.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 154.7;EFO-21: 211.3;MCF7: 168.0;OE19: 153.2;PC-3: 266.8;SK-BR-3: 134.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044657, HPA071160" Approved Approved "Nuclear bodies,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "Nuclear bodies, Plasma membrane" "Vesicles, Cytosol" "HPA044657: AB_10967927, HPA071160: " "unprognostic (2.03e-1)" "unprognostic (1.28e-1)" "unprognostic (1.43e-1)" "unprognostic (1.48e-2)" "unprognostic (9.44e-3)" "unprognostic (6.81e-3)" "prognostic unfavorable (8.00e-4)" "unprognostic (2.23e-1)" "unprognostic (3.65e-1)" "unprognostic (2.76e-1)" "unprognostic (8.22e-3)" "unprognostic (2.36e-2)" "prognostic unfavorable (1.25e-4)" "unprognostic (8.49e-2)" "unprognostic (4.66e-2)" "unprognostic (6.34e-2)" "unprognostic (3.78e-3)" 70.1 5.3 22.8 15.3 37.6 1.0 61.0 35.0 34.1 16.4 14.9 62.5 38.8 32.6 8.5 10.8 24.6 27.4 16.9 23.6 25.4 25.9 4.6 34.4 8.7 36.9 33.4 3.4 20.0 3.2 6.6 28.1 33.7 34.5 39.4 3.1 26.6 24.7 17.9 10.6 38.8 31.3 30.0 26.7 75.3 9.5 34.5 3.6 14.5 5.6 7.5 46.0 14.9 62.4 51.3 103.9 2.1 0.3 2.3 0.0 12.0 0.2 1.9 2.6 6.8 45.1 154.7 0.0 211.3 2.3 9.2 101.2 7.2 11.5 3.0 42.1 20.4 2.9 3.5 10.0 1.1 0.1 1.8 2.2 3.1 1.4 1.5 7.5 39.4 20.5 1.1 0.0 1.2 168.0 0.6 0.9 2.6 153.2 266.8 4.0 2.1 2.0 29.7 92.9 34.5 13.2 0.6 134.8 17.9 17.3 59.3 2.2 34.5 0.2 0.8 0.1 17.5 1.2 6.1 1.0 1.1 0.1 0.2 0.0 0.0 0.0 2.3 0.0 19.5 0.0 3.1 2.8 3.3 0.0 1.0 0.2 0.0 0.1 0.0 0.2 1.1 0.5 22.8 37.6 35.0 34.1 23.6 25.4 36.9 33.4 33.7 30.0 34.5 62.4 108.8 32.1 6.9 4.9 1.5 3.6 10.9 59.6 2.2 2.9 45.1 15.6 1.7 31.5 29.5 29.5 6.2 2.0 1.6 125.8 3.9 125.2 27.9 25.5 3.8 48.4 40.2 8.0 1.7 189.3 11.9 8.2 71.4 36.6 1.3 2.5 10.4 0.1 25.3 1.7 1.0 106.7 36.7 8.5 16.1 6.6 0.6 9.8 28.4 15.0 15.6 44.7 0.0 11.1 75.3 193.4 120.9 0.0 0.2 50.4 68.3 1.8 27.6 1.5 13.1 39.7 26.8 4.3 18.5 2.9 3.1 3.0 3.9 7.5 66.3 29.6 TSPAN8 "CO-029, TM4SF3" ENSG00000127324 "Tetraspanin 8" P19075 12 71125085-71441898 "Cancer-related genes, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 951.1;stomach 1: 631.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1688.5;Ductal cells: 943.3;Intestinal goblet cells: 886.7;Paneth cells: 2225.8;Proximal enterocytes: 3546.1;Undifferentiated cells: 1583.9" "Group enriched" "Detected in many" 4 "colorectal cancer: 283.9;pancreatic cancer: 156.9;stomach cancer: 194.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "OE19: 2160.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA022273, CAB026009, HPA044337" Enhanced Approved Vesicles NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Vesicles "CAB026009: , HPA022273: , HPA044337: AB_2678899" "unprognostic (1.64e-1)" "unprognostic (2.18e-2)" "unprognostic (1.64e-1)" "unprognostic (6.40e-2)" "unprognostic (6.81e-2)" "unprognostic (7.29e-3)" "unprognostic (1.90e-1)" "unprognostic (1.15e-1)" "unprognostic (5.62e-2)" "unprognostic (1.06e-1)" "unprognostic (4.01e-3)" "unprognostic (2.93e-1)" "prognostic unfavorable (9.66e-5)" "unprognostic (1.88e-2)" "unprognostic (1.00e-1)" "unprognostic (2.97e-2)" "prognostic favorable (7.36e-5)" 11.1 9.7 1.9 126.9 5.2 0.0 17.0 6.1 7.1 28.6 1.6 951.1 916.0 12.5 11.7 5.5 13.4 208.2 5.5 1.8 3.4 57.6 53.2 23.0 4.6 12.4 4.9 41.8 60.0 0.4 2.5 2.0 10.5 163.9 862.0 0.3 76.4 10.8 63.7 13.6 848.3 39.2 8.5 0.3 631.0 5.8 4.4 1.1 6.5 12.4 3.8 11.0 4.0 14.6 0.0 0.7 0.0 0.0 5.2 0.8 2.8 0.0 0.0 0.0 0.0 48.8 3.1 0.0 0.2 0.0 0.6 6.5 0.0 0.0 0.0 0.2 0.1 0.0 52.2 3.3 0.0 0.0 0.2 0.4 0.3 0.0 0.0 0.0 12.4 0.0 0.0 0.0 0.3 0.0 0.2 3.0 0.3 2160.7 173.3 0.2 0.0 4.9 34.1 41.0 4.1 7.7 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.3 1.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 5.2 6.1 7.1 1.8 3.4 12.4 4.9 10.5 8.5 4.4 14.6 0.8 0.0 2.2 0.0 6.1 20.8 32.5 14.0 0.6 0.3 8.5 1.8 0.3 346.0 76.7 44.1 0.0 1.2 0.0 1688.5 127.2 943.3 34.5 3.7 4.5 3.8 174.1 0.0 0.1 654.9 0.6 37.3 645.3 44.8 4.5 0.0 2.2 26.0 0.2 0.0 0.1 886.7 16.2 2.2 29.1 17.9 44.1 2.6 64.0 0.0 7.8 10.3 0.0 0.5 14.3 325.0 2225.8 32.0 2.2 376.2 3546.1 2.5 30.2 0.6 0.0 7.7 23.6 0.5 1.0 2.7 13.5 1.1 5.8 10.7 1583.9 46.0 TSPO "BZRP, DBI, IBP, MBR, mDRC, PBR, pk18, PKBS" ENSG00000100300 "Translocator protein" "B1AH88, P30536" 22 43151547-43163242 "Cancer-related genes, FDA approved drug targets, Predicted membrane proteins" "Lipid transport, Transport" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 690.1" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1429.2;Pancreatic endocrine cells: 1442.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPMI-8226: 516.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011232, HPA046260, HPA072304" Uncertain Supported Vesicles,Mitochondria,Cytosol NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" Mitochondria "Vesicles, Cytosol" "CAB011232: , HPA046260: , HPA072304: " "unprognostic (5.29e-3)" "unprognostic (1.41e-1)" "unprognostic (3.31e-1)" "unprognostic (4.02e-3)" "unprognostic (3.95e-1)" "unprognostic (1.46e-2)" "prognostic unfavorable (1.61e-4)" "unprognostic (2.16e-1)" "unprognostic (1.17e-1)" "unprognostic (3.75e-2)" "unprognostic (1.07e-2)" "unprognostic (1.33e-1)" "unprognostic (1.69e-1)" "unprognostic (1.53e-2)" "unprognostic (3.03e-1)" "unprognostic (1.04e-1)" "unprognostic (2.34e-3)" 249.3 164.5 42.3 65.3 46.3 488.7 204.3 50.9 61.1 217.3 45.8 189.7 73.6 91.8 8.7 690.1 108.5 39.4 174.7 39.9 51.0 120.5 81.9 181.5 44.3 61.9 48.8 72.3 93.4 22.4 50.8 30.5 57.4 126.6 33.9 4.2 244.9 28.9 84.0 388.0 116.9 26.6 58.0 206.9 216.9 21.4 59.5 22.2 77.4 27.5 39.9 135.7 355.5 69.0 300.0 143.3 10.2 134.4 54.7 175.3 10.8 216.6 107.0 109.4 115.7 28.8 222.4 0.3 147.8 175.7 52.2 242.2 27.9 171.7 13.9 49.5 111.4 28.9 150.4 10.1 193.4 66.4 145.0 137.5 276.4 65.9 58.2 125.8 262.9 0.2 24.0 53.6 114.2 244.5 1.1 188.5 11.6 154.0 355.7 67.0 0.0 516.2 139.3 173.8 14.0 65.4 103.9 200.4 263.5 0.1 76.3 256.6 269.7 132.6 96.9 135.5 92.9 21.7 4.1 2.7 170.0 218.3 171.4 656.8 1678.5 931.0 314.7 1051.6 247.7 199.2 429.9 309.2 1170.2 266.9 325.9 264.3 1052.3 365.0 713.1 209.0 539.5 1585.6 42.3 46.3 50.9 61.1 39.9 51.0 61.9 48.8 57.4 58.0 59.5 69.0 225.5 160.3 140.0 3.6 88.9 366.8 392.3 1429.2 554.3 2.8 269.3 360.2 92.1 323.1 555.7 206.0 2.1 10.0 140.3 680.7 369.8 578.5 2.4 170.8 143.6 220.4 194.9 239.9 0.3 586.4 284.9 205.1 440.9 309.5 268.6 124.3 187.1 110.5 758.5 3.3 0.8 636.8 478.1 644.7 524.7 11.7 82.6 611.6 723.9 10.3 776.9 180.5 207.0 6.0 20.1 1442.1 705.9 157.6 76.3 526.2 471.9 180.7 283.2 19.4 105.2 108.2 197.8 2.8 4.5 1067.4 536.0 20.0 180.0 30.5 664.1 786.1 TTC25 DKFZP434H0115 ENSG00000204815 "Tetratricopeptide repeat domain 25" Q96NG3 17 41930617-41966503 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "fallopian tube: 17.0;testis: 44.9" "Cell type enhanced" "Detected in many" "Early spermatids: 227.2;Endometrial ciliated cells: 65.3;Late spermatids: 43.5;Respiratory ciliated cells: 79.4;Spermatocytes: 98.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 3.0;U-87 MG: 2.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA023908 Enhanced Uncertain Vesicles,Centrosome NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" Centrosome Vesicles "HPA023908: AB_2241243" "unprognostic (3.08e-3)" "unprognostic (4.51e-2)" "unprognostic (6.96e-2)" "unprognostic (1.23e-3)" "unprognostic (1.93e-1)" "unprognostic (4.57e-2)" "unprognostic (4.11e-2)" "unprognostic (1.41e-1)" "unprognostic (2.05e-1)" "unprognostic (1.05e-1)" "unprognostic (3.31e-4)" "unprognostic (2.95e-2)" "unprognostic (2.99e-2)" "unprognostic (2.10e-2)" "unprognostic (9.21e-3)" "unprognostic (3.76e-1)" "unprognostic (2.71e-1)" 0.6 0.6 1.8 0.0 1.8 2.7 0.8 1.6 1.8 2.6 6.8 1.1 0.1 1.5 1.3 0.1 17.0 0.5 0.7 1.8 2.4 2.0 0.4 2.8 0.1 3.1 3.3 1.3 0.7 1.9 5.6 0.3 2.4 0.9 0.1 1.7 0.3 0.4 0.5 0.4 0.3 0.5 2.2 0.2 0.5 44.9 2.6 0.3 2.0 0.2 0.0 0.8 0.5 1.7 0.1 1.2 1.4 1.4 0.3 0.3 0.2 0.0 0.6 0.2 0.3 0.2 1.0 0.1 0.5 0.2 0.4 0.3 0.2 0.1 0.3 0.2 0.3 0.3 0.3 0.0 0.4 0.0 0.7 0.2 0.2 0.6 0.0 0.8 0.0 0.7 0.1 0.8 0.2 0.8 0.8 0.1 0.4 0.0 0.1 0.0 0.1 1.0 1.3 0.1 3.0 2.0 0.1 0.4 1.1 0.4 0.5 0.3 0.0 0.1 0.6 0.5 0.3 1.0 0.9 0.1 2.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.8 1.8 1.6 1.8 1.8 2.4 3.1 3.3 2.4 2.2 2.6 1.7 0.4 3.2 4.8 2.9 0.0 0.0 0.5 0.0 0.0 2.7 0.5 1.1 1.6 1.5 14.9 3.7 8.4 0.5 0.0 0.3 1.9 2.3 227.2 65.3 2.6 0.9 0.0 18.7 5.2 0.8 0.7 3.0 0.5 3.1 3.8 0.6 0.7 0.2 0.4 3.3 4.6 0.2 0.0 0.0 0.0 43.5 3.4 0.4 0.0 1.0 0.2 2.8 0.0 1.0 0.7 0.4 0.1 1.9 0.0 0.2 0.0 3.4 79.4 5.2 13.1 4.1 0.6 98.4 3.5 0.0 0.0 0.1 0.2 1.5 0.2 0.3 TTC33 OSRF ENSG00000113638 "Tetratricopeptide repeat domain 33" Q6PID6 5 40512333-40755963 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038252, HPA038253" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 20: HeLa - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Golgi apparatus, Vesicles" "HPA038252: AB_10674551, HPA038253: AB_10671739" "unprognostic (2.86e-1)" "unprognostic (1.11e-1)" "unprognostic (1.18e-2)" "unprognostic (1.17e-1)" "unprognostic (2.70e-2)" "unprognostic (1.13e-1)" "unprognostic (3.41e-3)" "unprognostic (1.04e-3)" "unprognostic (3.01e-2)" "unprognostic (1.99e-1)" "unprognostic (2.01e-1)" "unprognostic (2.60e-1)" "prognostic favorable (1.83e-4)" "unprognostic (8.50e-2)" "unprognostic (1.29e-1)" "unprognostic (2.04e-2)" "unprognostic (4.28e-3)" 6.9 5.9 6.6 3.3 7.2 0.8 5.7 10.0 9.7 5.8 5.3 6.3 4.3 6.2 4.7 4.2 5.6 4.6 6.3 7.5 6.6 7.5 7.7 5.1 4.3 6.3 6.5 6.7 4.8 8.9 4.4 4.1 6.3 5.9 4.2 11.6 5.3 5.6 15.5 3.8 4.8 5.0 5.6 4.6 5.2 4.5 7.3 6.7 6.0 14.8 4.1 5.4 5.2 6.9 3.6 3.2 6.1 6.8 5.0 7.1 2.9 4.7 5.6 4.8 5.1 1.7 3.5 11.0 2.8 4.3 5.2 1.6 5.2 2.7 8.5 10.3 4.9 2.4 13.5 4.3 5.5 6.5 3.1 4.4 5.6 4.8 5.0 8.4 7.2 7.3 5.8 8.3 6.4 1.0 12.5 9.3 1.9 2.8 3.5 11.1 11.5 7.9 8.2 2.1 4.5 6.2 11.0 6.4 8.1 5.0 4.3 8.7 5.5 5.5 4.6 4.3 4.6 6.0 6.7 5.8 5.1 10.1 4.9 7.1 1.8 3.2 2.0 4.4 2.2 2.1 2.3 2.1 1.9 2.2 2.5 2.2 2.5 2.3 6.6 1.0 2.2 1.9 6.6 7.2 10.0 9.7 7.5 6.6 6.3 6.5 6.3 5.6 7.3 6.9 12.9 16.0 7.4 9.8 13.1 14.4 5.6 8.6 11.4 12.3 8.6 6.0 18.2 7.2 6.2 7.3 6.2 5.9 8.8 6.9 19.6 8.2 22.4 9.1 11.5 11.0 3.0 9.5 23.7 6.3 4.2 12.6 6.1 6.8 12.7 8.9 13.9 9.4 5.1 5.0 27.5 8.0 10.2 7.5 15.4 8.4 14.0 7.5 10.6 15.9 14.3 19.2 2.1 23.6 35.1 8.0 8.4 13.9 11.8 6.8 6.8 12.6 13.7 23.5 13.1 9.9 13.4 28.1 22.1 6.3 18.3 2.6 14.6 5.0 6.2 4.5 TTC9B FLJ30373 ENSG00000174521 "Tetratricopeptide repeat domain 9B" Q8N6N2 19 40216058-40218399 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 41 "brain: 110.8;choroid plexus: 32.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 39.1;Excitatory neurons: 39.3;Horizontal cells: 18.5;Inhibitory neurons: 19.7;Oligodendrocyte precursor cells: 27.2" "Cancer enriched" "Detected in single" 15 "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "SCLC-21H: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042496 Approved Approved Nucleoplasm,Vesicles,Mitochondria "Secreted in brain" NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Mitochondria" Vesicles "HPA042496: AB_10795506" "unprognostic (2.31e-1)" "unprognostic (1.39e-4)" "unprognostic (5.09e-2)" "unprognostic (5.24e-2)" "unprognostic (8.47e-2)" "unprognostic (1.05e-1)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (7.95e-2)" "unprognostic (2.78e-1)" "unprognostic (1.54e-2)" "unprognostic (3.69e-1)" "unprognostic (8.75e-6)" "unprognostic (1.39e-1)" "unprognostic (8.23e-2)" "unprognostic (1.95e-1)" "unprognostic (5.24e-2)" 0.0 0.6 73.9 0.3 74.7 0.0 0.0 49.7 110.8 0.0 32.9 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 84.2 60.6 0.2 0.0 0.0 0.0 45.1 46.3 0.0 0.0 0.0 0.9 0.0 46.4 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.5 0.1 43.0 0.0 0.2 0.3 60.4 0.0 0.0 0.0 0.0 0.0 0.1 69.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 26.8 1.4 0.1 0.0 1.0 0.0 0.1 0.0 0.0 0.3 0.4 0.1 0.0 0.3 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 73.9 74.7 49.7 110.8 84.2 60.6 45.1 46.3 46.4 43.0 60.4 69.0 0.0 0.0 0.0 2.9 0.0 0.0 0.1 0.1 0.0 39.1 0.2 0.0 2.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 1.8 0.2 0.2 1.8 0.0 39.3 0.5 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 18.5 19.7 0.1 0.0 0.0 0.0 1.0 0.3 0.0 0.0 4.7 0.0 1.7 0.0 27.2 5.0 0.1 1.2 0.7 0.0 0.1 0.0 0.0 1.2 8.4 0.0 0.0 0.1 7.0 8.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 TTI1 "KIAA0406, smg-10" ENSG00000101407 "TELO2 interacting protein 1" O43156 20 37983007-38033461 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034230, HPA068338" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 23: Testis - Cell cycle regulation" "Cluster 39: CACO-2 - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Vesicles Nucleoplasm "CAB034230: AB_1564322, HPA068338: AB_2685975" "unprognostic (7.14e-3)" "unprognostic (3.15e-1)" "unprognostic (6.61e-2)" "prognostic unfavorable (3.30e-5)" "unprognostic (1.11e-1)" "unprognostic (5.37e-2)" "prognostic unfavorable (2.40e-7)" "unprognostic (5.05e-2)" "unprognostic (1.41e-1)" "unprognostic (1.70e-1)" "unprognostic (4.49e-2)" "unprognostic (2.36e-1)" "unprognostic (9.03e-2)" "unprognostic (1.94e-1)" "unprognostic (5.80e-2)" "unprognostic (7.56e-3)" "unprognostic (1.34e-1)" 6.8 9.5 7.4 9.1 7.7 8.7 8.9 7.5 8.0 8.5 8.1 7.7 6.2 9.7 9.8 7.3 10.0 6.0 8.2 7.3 8.0 8.5 12.0 7.5 11.8 7.4 7.2 11.8 13.9 11.0 10.0 10.9 7.5 9.4 10.6 10.0 10.1 11.1 16.0 8.0 7.5 10.0 6.8 9.3 8.7 11.0 7.6 13.8 12.1 10.2 12.8 9.0 7.4 10.3 21.7 31.6 34.3 13.1 13.7 19.0 36.7 24.1 14.1 35.2 29.8 74.3 27.5 35.5 24.5 13.8 39.1 33.7 38.8 50.5 34.5 14.3 15.2 48.9 31.3 38.6 15.5 39.4 22.0 14.6 32.6 35.0 21.1 13.5 26.5 37.1 52.3 23.6 26.9 22.3 53.7 27.3 33.7 33.7 32.9 34.7 55.2 41.6 13.4 23.0 31.1 27.7 36.9 64.5 8.6 35.1 36.6 18.8 17.6 47.0 31.2 25.3 24.9 20.4 19.1 39.5 27.5 25.5 24.8 13.8 8.2 15.0 9.3 9.5 10.4 7.9 7.1 9.2 10.8 7.7 10.5 8.5 5.1 9.6 6.1 5.2 9.9 7.9 7.4 7.7 7.5 8.0 7.3 8.0 7.4 7.2 7.5 6.8 7.6 10.3 6.1 9.6 11.6 16.3 9.2 3.1 3.6 5.1 4.0 8.5 5.0 5.0 12.3 7.2 8.3 3.7 10.4 15.1 5.9 3.4 1.9 5.7 8.9 5.1 6.8 6.9 3.0 9.9 15.9 3.2 10.7 7.0 5.1 5.2 2.5 16.8 3.3 8.4 5.5 8.4 14.6 4.4 4.1 1.6 2.0 3.9 6.5 5.0 3.6 14.0 7.5 5.9 6.2 15.6 25.4 3.9 5.3 6.8 10.5 6.0 3.9 5.0 15.8 9.1 0.0 5.3 5.5 14.5 12.9 4.2 3.0 14.4 8.9 8.2 6.3 4.4 TTL MGC46235 ENSG00000114999 "Tubulin tyrosine ligase" Q8NG68 2 112482156-112541739 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 72.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA066819 Approved Nucleoplasm,Vesicles NA NA "Cluster 17: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles Nucleoplasm "HPA066819: AB_2685728" "unprognostic (1.05e-2)" "unprognostic (3.90e-3)" "unprognostic (2.25e-1)" "unprognostic (3.95e-3)" "unprognostic (9.75e-2)" "unprognostic (1.81e-2)" "prognostic unfavorable (5.65e-4)" "unprognostic (2.95e-1)" "unprognostic (3.65e-1)" "unprognostic (2.10e-1)" "unprognostic (5.48e-2)" "unprognostic (7.19e-2)" "unprognostic (6.12e-2)" "unprognostic (1.30e-1)" "unprognostic (1.45e-1)" "unprognostic (2.01e-1)" "unprognostic (4.55e-2)" 1.0 0.8 2.3 0.9 3.0 1.8 0.6 1.6 3.0 0.6 0.1 0.8 0.6 1.0 0.8 1.1 0.5 1.1 1.6 2.4 1.7 0.8 0.6 1.3 1.0 1.5 1.9 0.6 0.8 0.8 0.3 1.2 1.6 0.6 0.8 1.4 0.4 0.7 3.7 1.4 0.6 1.3 0.8 0.9 0.6 0.6 2.7 1.0 0.9 3.8 0.8 1.0 0.4 3.5 2.9 2.2 2.7 6.2 3.2 4.6 1.1 4.9 4.0 5.1 4.4 2.7 1.0 2.7 2.7 4.2 3.3 2.0 4.8 2.5 6.2 1.9 2.7 2.3 3.1 3.4 1.4 3.2 1.1 2.1 1.7 7.5 4.0 2.3 4.4 1.8 3.8 2.1 4.1 1.5 2.8 1.8 2.4 0.8 4.4 3.0 3.1 1.5 1.6 2.2 5.8 4.0 3.8 1.2 6.7 1.8 1.3 1.8 4.4 6.0 4.4 4.8 3.7 1.1 2.5 2.2 6.7 2.4 2.6 0.6 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 0.3 0.1 0.2 0.2 0.1 0.0 2.3 3.0 1.6 3.0 2.4 1.7 1.5 1.9 1.6 0.8 2.7 3.5 14.0 12.8 6.4 19.2 7.0 20.3 4.9 8.3 4.6 15.6 6.4 6.0 39.1 2.8 6.7 12.9 12.5 3.2 10.6 8.0 0.0 7.2 12.2 8.3 28.3 18.5 11.3 16.2 34.1 9.6 2.4 12.6 2.6 10.8 0.0 11.7 15.7 10.4 11.4 8.4 24.0 5.8 16.2 24.2 19.2 5.1 3.1 17.0 7.2 20.6 17.2 9.8 8.2 24.6 72.8 9.4 5.2 5.7 9.1 6.6 2.4 6.0 4.2 20.2 6.6 15.4 12.2 4.5 5.0 6.5 18.0 1.2 7.6 7.7 6.1 4.1 TTLL6 FLJ35808 ENSG00000170703 "Tubulin tyrosine ligase like 6" Q8N841 17 48762235-48817214 "Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 18.9" "Group enriched" "Detected in some" 4 "Early spermatids: 49.7;Late spermatids: 176.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "HDLM-2: 4.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA052397 Enhanced Approved Vesicles,Microtubules NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" Microtubules Vesicles "HPA052397: AB_2681812" "unprognostic (5.74e-2)" "unprognostic (3.29e-1)" "unprognostic (1.26e-1)" "unprognostic (2.18e-1)" "unprognostic (8.04e-2)" "unprognostic (2.95e-1)" "unprognostic (1.85e-2)" "unprognostic (1.02e-1)" "unprognostic (1.27e-2)" "unprognostic (2.35e-1)" "unprognostic (2.21e-5)" "unprognostic (1.10e-2)" "unprognostic (6.01e-5)" "unprognostic (1.17e-1)" "unprognostic (3.28e-1)" "unprognostic (6.68e-2)" "unprognostic (2.09e-3)" 0.1 0.0 0.6 0.1 0.6 0.0 0.1 0.5 1.0 0.2 1.6 2.8 1.3 0.1 0.0 0.0 3.6 0.5 0.0 0.7 0.6 2.5 0.0 0.6 0.0 0.8 0.9 0.0 0.6 0.0 0.4 0.0 0.6 0.1 3.9 0.4 0.0 0.0 0.0 0.0 1.7 0.1 0.6 0.0 0.2 18.9 0.8 0.1 0.1 0.0 0.0 0.0 0.1 0.6 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 4.5 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.5 1.0 0.7 0.6 0.8 0.9 0.6 0.6 0.8 0.6 0.1 3.2 2.6 5.2 0.2 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.6 0.0 3.8 1.8 0.0 0.0 0.0 7.4 1.9 0.3 49.7 2.6 0.1 0.5 4.2 0.0 1.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.5 0.1 0.1 0.0 1.0 2.6 0.0 0.0 0.0 176.1 1.2 0.1 0.0 0.0 0.0 0.4 0.0 13.0 0.7 0.0 2.2 0.0 0.0 0.4 4.1 3.2 23.8 0.7 0.0 0.0 0.0 11.2 0.4 0.0 0.0 0.0 0.0 0.4 3.5 0.1 TUFT1 ENSG00000143367 "Tuftelin 1" Q9NNX1 1 151540305-151583583 "Predicted intracellular proteins, Predicted secreted proteins" Biomineralization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 111.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 69.2;Glandular and luminal cells: 76.8;Suprabasal keratinocytes: 66.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.2" "Group enriched" "Detected in many" 5 "granulocytes: 5.2;T-cells: 3.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 41.7" "HPA028112, HPA054301" Approved Approved Approved Vesicles "Secreted - unknown location" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Vesicles "HPA028112: AB_10603224, HPA054301: AB_2682442" "unprognostic (6.16e-2)" "unprognostic (3.76e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (4.83e-4)" "unprognostic (4.49e-3)" "unprognostic (1.12e-1)" "unprognostic (2.30e-2)" "unprognostic (1.37e-2)" "unprognostic (8.29e-3)" "unprognostic (9.06e-2)" "unprognostic (6.70e-3)" "unprognostic (7.88e-2)" "unprognostic (2.58e-3)" "unprognostic (1.41e-1)" "unprognostic (1.32e-1)" "unprognostic (1.82e-3)" "unprognostic (4.53e-2)" 5.6 6.8 4.7 2.8 4.2 6.7 10.1 5.0 5.3 25.4 3.4 11.6 7.5 5.3 6.3 48.1 5.1 5.9 4.9 3.8 5.9 14.1 7.0 8.4 0.9 4.0 4.0 7.4 17.2 11.4 7.2 13.3 5.2 9.6 13.0 2.1 18.3 9.2 2.5 111.5 10.8 6.2 3.3 1.5 12.8 5.4 6.2 2.2 5.7 2.7 6.2 12.4 26.8 3.5 40.7 13.7 10.0 11.5 2.3 1.9 63.1 10.7 9.5 41.3 39.6 43.6 31.5 3.5 64.6 12.5 19.5 46.4 17.6 16.2 30.1 27.0 8.7 2.2 23.0 6.7 32.2 0.8 4.7 6.5 18.9 32.5 71.6 24.5 3.4 5.0 3.6 26.8 12.8 16.8 2.0 0.5 11.7 29.6 11.4 0.1 28.1 14.2 34.7 61.8 19.5 8.0 68.2 45.8 8.0 29.4 36.5 2.1 8.6 7.4 51.7 46.2 71.7 6.6 13.7 0.5 6.3 0.9 4.7 5.2 0.6 0.7 0.3 0.1 0.7 0.6 1.0 0.5 0.9 0.2 0.8 0.3 2.5 0.1 0.3 0.1 3.5 0.5 4.7 4.2 5.0 5.3 3.8 5.9 4.0 4.0 5.2 3.3 6.2 3.5 2.1 25.6 2.0 1.6 3.8 69.2 35.2 14.7 35.9 2.5 28.8 20.2 9.8 8.6 19.0 14.7 0.0 28.1 6.6 59.5 13.7 18.2 2.7 43.2 8.9 2.7 32.2 2.7 4.4 15.2 13.9 7.0 46.9 76.8 4.5 9.0 1.1 10.5 4.0 0.0 9.3 39.1 20.3 0.0 12.7 3.2 2.5 6.5 8.8 1.0 2.0 2.1 0.0 8.5 1.8 47.4 34.6 5.3 7.7 21.7 15.4 11.2 15.9 0.5 6.6 4.1 5.5 0.6 3.5 39.6 66.5 56.8 5.8 10.9 35.7 35.6 TUSC1 "CCDC89B, TSG-9" ENSG00000198680 "Tumor suppressor candidate 1" Q2TAM9 9 25676389-25678440 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 164.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 38.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051426 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles Nucleoplasm "HPA051426: AB_2681481" "unprognostic (9.84e-2)" "unprognostic (3.56e-1)" "unprognostic (2.58e-1)" "unprognostic (2.11e-3)" "unprognostic (9.41e-3)" "unprognostic (1.78e-1)" "unprognostic (4.79e-3)" "unprognostic (1.72e-2)" "unprognostic (5.71e-2)" "unprognostic (1.85e-3)" "unprognostic (9.14e-3)" "unprognostic (1.03e-2)" "unprognostic (1.89e-3)" "unprognostic (2.88e-2)" "unprognostic (1.08e-1)" "unprognostic (2.37e-1)" "unprognostic (2.21e-2)" 16.1 10.6 8.5 2.8 8.5 1.7 14.8 7.0 9.3 13.6 9.5 14.3 5.3 18.3 6.2 9.1 15.9 2.8 12.2 8.7 8.9 13.1 10.9 9.8 1.6 9.6 10.5 13.2 9.8 5.6 9.0 3.8 8.2 11.7 3.7 2.8 10.8 6.1 8.3 13.1 9.1 5.5 9.0 6.8 11.5 21.8 8.6 3.2 11.9 4.7 2.0 12.7 10.7 10.4 10.0 2.1 2.1 0.0 7.0 5.8 0.1 7.5 0.0 2.8 3.4 0.1 3.5 0.0 2.2 8.9 7.6 0.0 5.3 9.4 1.7 0.0 10.3 38.6 11.2 0.0 3.4 0.0 0.0 7.1 13.0 3.1 7.3 0.0 3.1 0.0 0.0 0.1 3.3 5.0 0.0 0.1 1.8 8.0 9.5 0.0 1.4 0.1 3.9 4.6 0.7 16.8 9.3 7.6 8.2 4.1 6.7 10.8 6.6 0.0 13.6 0.1 0.0 0.0 0.0 0.0 8.8 2.6 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 8.5 8.5 7.0 9.3 8.7 8.9 9.6 10.5 8.2 9.0 8.6 10.4 46.5 12.8 6.4 2.3 2.1 60.8 46.1 14.7 47.3 24.8 45.4 55.0 12.2 20.0 5.9 16.5 4.2 29.5 2.4 14.8 66.5 7.9 85.7 11.0 26.6 24.4 13.1 4.8 7.3 12.4 13.8 33.0 7.1 17.2 0.0 15.7 22.9 18.5 9.7 21.9 7.6 11.8 10.2 4.8 13.0 16.2 30.7 5.2 28.4 3.7 1.2 42.9 0.0 4.0 9.3 8.1 9.5 21.8 0.5 45.5 8.1 23.1 3.5 14.3 32.9 52.8 36.9 164.0 12.8 16.8 37.8 29.0 1.3 16.3 14.3 19.8 TUSC2 "C3orf11, FUS1, PAP, PDAP2" ENSG00000114383 "Tumor suppressor 2, mitochondrial calcium regulator" O75896 3 50320027-50328251 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 351.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030116 Approved Vesicles,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 31: Spermatids - Spermatogenesis" Cytosol Vesicles "HPA030116: AB_10602253" "unprognostic (1.58e-2)" "unprognostic (1.55e-1)" "unprognostic (1.73e-1)" "unprognostic (8.46e-2)" "unprognostic (2.73e-1)" "unprognostic (2.81e-1)" "prognostic unfavorable (2.84e-4)" "unprognostic (2.53e-3)" "unprognostic (2.87e-1)" "unprognostic (1.20e-2)" "unprognostic (3.47e-2)" "unprognostic (1.99e-2)" "prognostic favorable (8.70e-7)" "unprognostic (9.22e-3)" "unprognostic (1.98e-1)" "unprognostic (3.15e-1)" "unprognostic (6.34e-3)" 17.7 25.4 53.4 14.9 54.1 12.4 17.0 51.0 56.2 16.3 43.9 25.2 12.8 17.7 28.2 18.9 20.6 11.5 35.4 54.8 55.5 29.2 25.9 18.4 17.1 54.6 56.2 15.8 27.4 34.8 21.5 17.3 55.6 22.1 16.6 36.0 18.4 17.8 50.9 13.8 20.3 13.7 50.5 23.7 26.9 22.6 56.1 20.4 23.1 36.4 20.5 20.5 14.2 50.8 24.7 20.2 27.5 30.1 29.8 15.4 30.1 19.3 26.5 36.3 30.7 35.6 22.0 41.8 21.0 18.3 37.4 15.5 33.9 25.7 31.7 24.8 31.2 20.6 18.6 38.7 26.1 36.7 34.8 16.8 40.7 36.5 18.1 25.5 38.0 32.8 25.4 19.6 21.1 18.8 38.7 46.5 37.6 30.4 28.9 13.3 13.4 34.4 36.9 26.4 14.7 30.3 14.4 25.4 29.9 27.2 24.2 44.3 30.3 10.8 26.6 24.8 40.2 47.6 79.7 29.4 24.2 24.1 17.4 16.7 21.2 34.6 24.0 19.6 24.3 23.0 20.8 25.2 14.2 24.6 23.5 25.2 30.2 22.4 18.1 26.3 25.2 32.3 53.4 54.1 51.0 56.2 54.8 55.5 54.6 56.2 55.6 50.5 56.1 50.8 39.8 12.8 17.0 3.9 41.7 57.5 36.8 60.7 37.0 55.5 61.0 44.2 39.6 55.8 37.9 57.0 22.9 62.9 54.4 46.5 115.4 73.9 123.1 55.6 15.8 39.2 50.4 40.4 12.9 74.1 55.5 24.9 25.0 28.4 29.9 16.4 40.4 72.7 76.6 74.0 11.4 46.1 73.2 46.1 51.1 351.8 27.1 37.7 55.2 5.6 57.6 69.0 59.8 4.0 7.8 74.0 61.0 24.8 45.8 67.8 72.0 178.6 71.5 45.5 13.1 18.0 38.5 54.1 49.2 47.4 91.2 69.6 38.7 28.9 46.1 63.7 TVP23A "FAM18A, YDR084C" ENSG00000166676 "Trans-golgi network vesicle protein 23 homolog A" A6NH52 16 10760919-10818794 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5.7" "Group enriched" "Detected in many" 6 "Excitatory neurons: 29.0;Granulosa cells: 92.1;Inhibitory neurons: 28.4;Langerhans cells: 47.6;monocytes: 29.1;Oligodendrocyte precursor cells: 23.6" "Cancer enhanced" "Detected in some" "glioma: 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 1.1;NTERA-2: 1.3;SH-SY5Y: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060582 Uncertain Approved Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA060582: AB_2684326" "unprognostic (6.70e-4)" "unprognostic (1.64e-3)" "unprognostic (2.38e-2)" "unprognostic (8.24e-3)" "unprognostic (2.72e-2)" "unprognostic (4.39e-5)" "unprognostic (4.96e-2)" "unprognostic (4.68e-2)" "unprognostic (4.42e-2)" "unprognostic (9.22e-2)" "unprognostic (1.73e-2)" "unprognostic (2.42e-1)" "unprognostic (8.78e-7)" "unprognostic (1.20e-3)" "unprognostic (1.14e-1)" "unprognostic (1.87e-2)" "unprognostic (2.87e-4)" 1.0 1.2 4.5 1.1 4.8 1.8 0.6 3.0 5.7 1.6 1.0 0.8 0.8 0.9 0.5 0.6 1.5 0.9 1.4 4.4 4.4 1.0 1.1 0.9 2.0 3.3 3.8 3.6 1.0 0.0 2.2 0.1 3.8 2.0 0.2 2.2 0.7 0.9 0.5 0.7 1.3 0.6 2.8 1.7 0.8 1.0 4.3 0.8 0.9 0.0 0.6 0.7 0.8 3.6 0.1 0.4 0.3 0.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.0 0.2 0.3 0.0 0.0 0.0 1.1 0.2 0.1 0.6 0.3 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.4 0.0 0.2 0.2 0.3 1.3 0.1 0.0 0.6 0.1 0.2 0.0 0.4 0.2 2.1 0.1 0.2 0.0 0.2 0.2 0.1 0.2 0.3 0.2 0.3 0.1 1.0 0.1 0.3 0.3 0.3 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.6 0.3 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.1 4.5 4.8 3.0 5.7 4.4 4.4 3.3 3.8 3.8 2.8 4.3 3.6 0.2 0.0 1.8 5.2 0.8 1.1 0.0 0.1 0.6 6.4 0.1 0.4 0.6 0.0 0.1 0.0 2.1 0.3 0.1 0.0 0.0 0.0 0.7 0.6 0.4 0.4 0.0 0.0 29.0 0.6 0.6 3.3 0.0 0.3 0.0 92.1 0.0 0.2 0.8 1.7 28.4 0.0 0.0 1.0 47.6 0.3 2.8 4.5 1.8 1.9 29.1 4.7 0.0 23.6 1.1 0.3 0.0 1.5 0.2 0.0 0.0 1.3 0.2 1.3 0.0 0.2 3.6 2.2 3.1 0.1 1.0 1.4 0.5 0.1 0.1 0.1 TXK "BTKL, PSCTK5, PTK4, RLK, TKL" ENSG00000074966 "TXK tyrosine kinase" P42681 4 48066393-48134250 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Transcription, Transcription regulation" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 12.4;lymphoid tissue: 15.8" "Cell type enhanced" "Detected in many" "dendritic cells: 84.1;NK-cells: 288.4;T-cells: 52.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "NK-cell: 152.3" "Group enriched" "Detected in many" 19 "NK-cells: 152.3;T-cells: 54.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 6.1;HMC-1: 14.0;U-266/70: 6.8;U-266/84: 9.2;WM-115: 32.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA062482 Approved Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 17: WM-115 - Nervous system development" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA062482: AB_2684778" "unprognostic (1.04e-2)" "unprognostic (2.21e-2)" "unprognostic (4.13e-2)" "unprognostic (9.24e-3)" "unprognostic (1.09e-2)" "unprognostic (2.58e-4)" "unprognostic (1.32e-1)" "unprognostic (1.94e-1)" "unprognostic (1.50e-1)" "unprognostic (6.39e-3)" "unprognostic (8.13e-2)" "unprognostic (4.06e-1)" "unprognostic (1.33e-1)" "unprognostic (1.37e-1)" "unprognostic (1.61e-1)" "unprognostic (2.59e-1)" "unprognostic (2.04e-2)" 0.9 1.0 0.1 7.8 0.0 5.6 0.9 0.0 0.4 0.8 0.3 1.5 1.8 1.0 12.4 1.5 2.0 2.2 0.6 0.0 0.5 1.1 2.1 2.8 15.8 1.2 0.2 0.2 0.8 0.4 0.7 1.9 1.5 0.5 1.4 2.0 1.4 0.5 0.6 2.2 5.6 0.4 0.2 10.6 1.1 1.1 0.8 5.7 1.2 0.0 10.8 2.2 0.9 0.2 3.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.5 0.1 6.1 0.0 1.8 0.0 0.2 0.3 0.0 0.1 0.6 0.3 0.1 3.1 0.0 0.0 0.0 0.4 14.0 0.0 0.0 0.1 0.0 0.9 0.2 0.6 0.2 0.1 0.8 0.0 0.0 2.8 0.0 0.8 1.0 0.4 0.0 0.0 1.7 1.6 0.0 0.3 0.0 0.0 1.6 0.1 0.0 0.2 0.5 0.0 0.0 0.4 0.1 6.8 9.2 0.6 0.0 0.5 32.0 5.4 0.1 1.0 42.0 0.2 54.8 0.2 21.1 20.2 0.2 0.1 53.2 37.0 2.4 152.3 0.3 0.6 17.6 36.3 0.1 0.0 0.0 0.4 0.0 0.5 1.2 0.2 1.5 0.2 0.8 0.2 0.7 0.0 1.8 0.3 3.2 0.4 0.6 0.0 0.6 0.5 0.8 0.4 1.1 1.5 0.0 0.0 4.2 0.4 84.1 0.2 1.9 1.5 10.1 2.0 0.4 0.9 0.0 10.7 21.5 0.0 0.1 0.6 0.0 5.5 1.3 0.1 3.6 1.5 1.6 0.0 3.3 0.2 0.0 6.9 0.4 2.8 0.3 1.9 1.8 3.7 1.6 1.4 288.4 0.5 0.5 0.1 0.1 0.0 8.9 0.6 0.4 0.5 0.0 0.4 0.0 1.2 0.1 1.0 0.8 0.8 1.1 0.5 52.3 0.1 0.4 0.8 TYR "OCA1, OCA1A, OCAIA" ENSG00000077498 Tyrosinase P14679 11 89177875-89295759 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Melanin biosynthesis" "Monooxygenase, Oxidoreductase, Tumor antigen" "Albinism, Deafness, Disease variant, FDA approved drug targets, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 37 "skin 1: 31.6" "Cell type enriched" "Detected in some" 5 "Melanocytes: 184.9" "Cancer enriched" "Detected in single" 1755 "melanoma: 351.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 995 "SK-MEL-30: 426.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000079, HPA043241, HPA050889, HPA064583" Enhanced Enhanced Vesicles NA NA "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "CAB000079: AB_564045, HPA043241: AB_2678383, HPA050889: AB_2681264, HPA064583: " "unprognostic (1.16e-1)" "unprognostic (1.01e-1)" "unprognostic (1.85e-3)" "unprognostic (9.75e-3)" 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 31.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 426.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.9 0.3 0.0 0.1 0.0 0.0 2.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 2.5 5.2 0.3 0.0 184.9 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 2.0 0.0 0.1 0.0 0.0 0.0 TYRP1 "b-PROTEIN, CAS2, CATB, GP75, OCA3, TRP, TYRP" ENSG00000107165 "Tyrosinase related protein 1" P17643 9 12685439-12710285 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Melanin biosynthesis" "Monooxygenase, Oxidoreductase" "Albinism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "choroid plexus: 44.8;heart muscle: 59.9;skin 1: 145.0" "Cell type enriched" "Detected in some" 17 "Melanocytes: 2486.6" "Cancer enriched" "Detected in some" 262 "melanoma: 313.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 55 "SK-MEL-30: 1395.0" "Group enriched" "Detected in some" 5 "olfactory bulb: 4.6;thalamus: 1.8" "Low region specificity" "Detected in all" "HPA000937, CAB002520" Enhanced Approved Vesicles NA NA 51000 "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "CAB002520: AB_564153, HPA000937: AB_1080437" "unprognostic (7.48e-2)" "unprognostic (1.10e-3)" "unprognostic (2.28e-1)" "unprognostic (3.16e-3)" "unprognostic (8.10e-2)" "unprognostic (3.82e-3)" "unprognostic (1.53e-1)" "unprognostic (2.25e-3)" "unprognostic (4.46e-1)" "unprognostic (8.71e-2)" "unprognostic (6.17e-2)" "unprognostic (2.42e-1)" "unprognostic (2.68e-6)" "unprognostic (1.27e-1)" "unprognostic (5.99e-2)" "unprognostic (1.95e-2)" 0.3 0.0 0.1 0.6 0.4 0.2 4.9 0.3 0.9 0.0 44.8 2.2 5.0 0.0 1.2 10.0 0.2 4.5 59.9 2.6 0.0 16.2 0.0 3.7 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.1 2.1 0.1 5.3 2.7 1.3 0.0 4.8 145.0 4.7 1.8 0.1 0.0 2.1 1.1 0.3 0.0 0.0 7.5 0.0 1.1 0.4 1.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 25.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.5 0.0 0.0 4.3 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.2 0.0 0.0 1395.0 0.1 19.5 1.5 0.0 0.0 0.7 0.0 0.9 0.0 0.7 0.4 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.3 0.9 2.6 0.0 1.2 1.1 2.1 0.1 0.3 1.0 0.0 0.0 0.0 0.0 0.0 92.3 0.1 0.0 0.0 11.7 0.0 0.0 44.3 0.0 0.0 3.7 2.1 0.0 0.0 0.0 144.8 0.3 2.5 0.0 0.0 1.3 0.0 0.0 0.9 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 17.5 4.7 0.3 0.0 2486.6 0.0 0.0 15.9 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 1.6 0.0 0.0 1.4 0.7 0.7 0.0 16.8 0.0 0.5 0.0 0.0 0.2 UBA5 "FLJ23251, UBE1DC1" ENSG00000081307 "Ubiquitin like modifier activating enzyme 5" Q9GZZ9 3 132654446-132679794 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Disease variant, Epilepsy, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 418.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017235, HPA076042" Supported Enhanced Vesicles,Cytosol NA NA 43000 "Cluster 15: NK-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" Cytosol Vesicles "HPA017235: AB_1858507, HPA076042: " "unprognostic (4.34e-3)" "unprognostic (6.44e-2)" "unprognostic (7.70e-2)" "unprognostic (3.49e-1)" "unprognostic (8.25e-2)" "unprognostic (1.25e-1)" "unprognostic (1.19e-2)" "unprognostic (3.06e-1)" "unprognostic (3.28e-2)" "unprognostic (1.47e-1)" "unprognostic (1.15e-2)" "unprognostic (1.84e-2)" "unprognostic (3.56e-1)" "unprognostic (1.47e-1)" "unprognostic (8.08e-2)" "unprognostic (1.02e-2)" "unprognostic (2.40e-2)" 18.3 29.2 15.6 18.6 17.5 21.5 23.0 15.2 16.3 18.0 30.9 21.5 24.0 17.2 30.4 17.2 16.6 16.9 23.8 16.7 15.8 31.3 31.8 17.7 22.4 12.6 13.6 16.9 52.1 31.0 22.3 25.8 14.1 24.8 22.6 25.2 48.0 20.2 31.4 22.0 24.8 17.7 13.8 21.1 26.7 17.0 14.2 19.7 31.8 24.4 24.9 17.2 11.8 16.5 67.2 24.4 42.1 35.3 28.4 31.9 44.5 57.1 57.2 34.4 39.6 44.9 24.2 52.1 41.1 40.8 23.3 39.6 41.6 43.6 49.5 51.3 18.1 63.6 39.6 50.1 27.9 79.6 36.7 28.0 24.8 32.8 48.7 31.8 38.6 28.6 41.0 76.2 38.0 59.4 44.1 29.2 38.6 56.3 22.9 38.6 37.0 99.8 31.0 50.9 40.2 35.8 33.5 32.0 51.3 37.8 40.0 39.5 35.9 36.7 36.2 17.8 29.8 71.7 51.8 98.3 40.9 28.1 33.5 8.3 7.1 7.0 12.4 8.2 14.6 15.1 13.8 19.1 15.9 10.2 16.1 16.3 1.6 26.0 9.5 19.2 15.5 10.5 15.6 17.5 15.2 16.3 16.7 15.8 12.6 13.6 14.1 13.8 14.2 16.5 23.1 35.3 25.9 37.2 24.0 17.2 18.9 26.4 21.1 22.1 26.1 13.1 36.9 22.8 24.4 7.3 14.6 63.0 28.4 8.3 68.4 30.3 124.8 17.7 22.2 20.5 21.6 10.9 37.6 44.9 48.0 24.8 28.5 17.4 24.1 16.8 13.2 22.8 22.6 21.9 35.6 22.6 34.6 10.3 11.4 418.2 16.8 13.9 17.8 16.9 21.6 26.1 16.5 37.7 28.4 23.2 16.7 27.1 85.4 23.1 35.4 43.1 20.8 23.6 32.9 23.5 28.2 49.4 23.1 15.9 18.5 99.7 20.4 29.7 18.3 18.1 UBA7 "D8, UBA1B, UBE1L, UBE2" ENSG00000182179 "Ubiquitin like modifier activating enzyme 7" P41226 3 49805209-49813953 "Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 52.5;granulocytes: 83.0;Proximal enterocytes: 51.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+ RasG12V: 56.7;HEL: 55.7;HMC-1: 103.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB015444, HPA058182" Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA 370000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Vesicles" Cytosol "CAB015444: AB_793598, HPA058182: AB_2683631" "prognostic favorable (1.55e-4)" "unprognostic (7.07e-3)" "unprognostic (1.59e-2)" "unprognostic (1.61e-2)" "unprognostic (3.77e-1)" "unprognostic (2.31e-2)" "unprognostic (5.08e-3)" "unprognostic (3.61e-2)" "unprognostic (6.33e-2)" "unprognostic (2.00e-1)" "unprognostic (1.40e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (1.04e-5)" "unprognostic (9.11e-2)" "unprognostic (3.81e-2)" "unprognostic (1.57e-1)" "prognostic favorable (1.48e-4)" 21.6 21.4 10.1 32.7 10.6 40.2 20.7 10.4 12.1 25.6 10.4 29.0 43.4 22.5 15.6 18.7 23.8 27.7 17.9 9.8 10.5 25.6 23.0 35.4 51.2 13.7 11.1 32.8 17.2 2.9 14.1 19.4 12.1 34.8 26.1 1.2 42.3 22.4 9.1 20.5 48.6 20.6 12.3 65.6 27.5 5.8 12.2 39.8 31.8 10.3 33.6 23.1 23.3 13.8 11.6 0.1 0.9 0.3 30.2 31.7 3.5 6.1 27.0 42.7 56.7 0.0 23.9 0.4 4.8 22.4 18.3 6.2 0.1 10.9 3.7 29.9 0.1 55.7 0.6 3.5 22.3 5.3 103.7 49.0 0.7 16.9 1.0 29.6 21.7 2.0 0.1 3.4 10.0 0.3 11.6 13.7 0.1 0.0 1.2 14.6 1.0 1.9 8.8 22.3 0.0 0.9 7.4 10.7 3.8 0.6 1.1 36.8 9.7 8.3 1.1 3.7 2.4 0.1 0.2 0.3 23.2 19.8 2.0 20.7 22.5 38.5 16.4 32.9 14.3 17.1 15.0 14.5 21.3 18.1 13.4 12.4 6.8 17.1 27.6 7.6 15.9 22.0 10.1 10.6 10.4 12.1 9.8 10.5 13.7 11.1 12.1 12.3 12.2 13.8 17.3 32.1 20.3 11.4 28.0 3.8 6.3 10.5 6.8 0.2 9.2 9.1 6.9 17.2 16.6 12.9 0.0 5.2 15.5 28.7 0.0 9.5 6.9 5.8 3.0 13.5 9.5 8.0 0.2 7.8 3.5 11.8 52.5 6.5 83.0 13.2 16.1 7.6 21.6 0.0 0.1 21.7 8.2 20.1 6.4 34.1 11.1 32.5 0.0 15.0 16.8 2.4 19.6 1.0 0.1 5.2 21.7 11.3 14.1 4.4 51.8 5.6 12.8 1.2 6.6 5.8 8.1 0.9 0.3 7.3 4.7 2.9 17.7 6.9 20.2 6.6 UBAP1 UBAP ENSG00000165006 "Ubiquitin associated protein 1" Q9NZ09 9 34179005-34252523 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019804 Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Cytosol "Vesicles, Plasma membrane" "HPA019804: AB_1858494" "unprognostic (1.83e-1)" "unprognostic (4.30e-2)" "unprognostic (1.29e-1)" "unprognostic (1.70e-1)" "unprognostic (3.54e-1)" "unprognostic (3.29e-2)" "unprognostic (1.67e-1)" "unprognostic (1.59e-1)" "unprognostic (2.01e-2)" "unprognostic (6.53e-2)" "unprognostic (1.25e-2)" "unprognostic (3.63e-1)" "prognostic favorable (7.49e-6)" "unprognostic (1.24e-1)" "unprognostic (1.49e-1)" "unprognostic (2.46e-1)" "unprognostic (1.17e-1)" 40.7 55.5 46.4 24.5 47.1 131.5 35.8 48.0 53.4 45.0 46.4 38.5 22.3 34.0 25.5 69.7 33.9 30.4 38.2 45.6 48.2 34.8 53.1 42.5 23.8 48.5 48.5 40.9 28.0 34.4 25.6 29.3 49.4 30.4 24.8 44.8 29.6 30.6 110.0 39.5 26.3 35.2 46.3 28.2 33.6 47.8 49.9 31.6 25.6 71.7 32.7 38.0 45.8 48.2 56.7 31.7 35.2 38.4 63.6 39.3 29.8 44.4 61.6 48.4 65.6 34.3 23.0 39.3 19.5 66.5 41.1 28.3 49.2 69.5 46.4 57.1 22.3 35.1 65.4 35.5 57.8 39.3 44.8 48.7 113.0 57.5 75.0 73.4 54.4 37.9 27.4 38.0 45.7 23.7 36.5 55.0 38.2 38.8 45.9 32.6 24.8 22.8 104.2 36.9 19.9 28.1 49.0 50.2 22.5 31.1 24.6 38.5 39.2 24.7 38.0 37.4 41.5 18.9 25.3 41.0 49.5 31.5 74.2 26.8 50.9 66.6 38.0 45.2 65.8 26.8 38.1 40.0 47.1 23.2 36.3 29.8 120.2 50.1 41.0 26.7 52.9 55.0 46.4 47.1 48.0 53.4 45.6 48.2 48.5 48.5 49.4 46.3 49.9 48.2 21.6 67.3 26.0 44.4 22.4 46.9 66.3 20.4 45.5 15.8 27.9 23.1 13.1 20.0 33.5 7.3 25.0 33.2 21.6 25.8 19.6 34.8 77.5 56.9 37.2 21.4 16.1 50.7 33.1 40.1 35.4 31.2 44.4 90.0 25.9 15.4 17.5 25.3 22.0 6.7 42.9 18.5 30.5 21.4 39.8 62.9 29.2 38.2 24.9 26.2 23.1 26.0 13.4 38.7 35.4 44.3 23.0 42.5 25.0 47.9 22.5 21.0 22.5 10.9 19.7 44.0 32.5 51.0 22.9 54.6 59.0 89.6 28.6 20.8 18.8 70.9 UBE2A "HHR6A, HR6A, RAD6A, UBC2" ENSG00000077721 "Ubiquitin conjugating enzyme E2 A" P49459 X 119574536-119591083 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 508.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: AB_2667061, HPA051765: AB_2681597, HPA065898: AB_2685577" "unprognostic (2.27e-3)" "prognostic favorable (2.16e-4)" "unprognostic (1.12e-1)" "unprognostic (9.09e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (9.07e-4)" "unprognostic (1.66e-3)" "unprognostic (1.96e-2)" "unprognostic (6.54e-2)" "unprognostic (2.96e-2)" "unprognostic (3.49e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (2.20e-6)" "unprognostic (9.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.21e-1)" "unprognostic (7.92e-2)" 40.0 27.4 30.1 39.1 30.6 29.8 29.4 34.1 38.8 34.1 27.1 52.3 37.5 32.0 38.2 53.4 27.3 32.6 63.2 29.6 32.2 41.0 30.1 32.9 46.9 34.4 32.5 20.1 29.2 39.2 18.9 56.8 34.4 31.0 45.0 27.1 30.9 33.0 71.9 30.7 39.1 43.0 32.1 26.8 30.5 17.6 32.1 46.1 30.5 55.0 50.4 46.9 32.8 35.1 129.5 104.1 60.8 54.1 103.0 125.6 63.9 122.6 106.3 141.8 130.3 50.8 84.0 96.4 126.4 133.9 240.6 86.4 86.3 65.7 128.6 142.3 60.6 42.7 71.9 47.1 96.6 105.9 72.1 86.9 90.1 134.0 58.3 98.1 99.4 86.5 57.0 83.6 160.1 134.5 166.6 99.9 106.3 125.7 126.9 84.2 64.0 91.6 113.1 76.6 48.9 51.3 171.2 75.0 93.7 73.2 65.8 92.6 101.5 92.4 42.0 184.3 142.5 83.6 147.1 92.4 99.1 136.3 74.6 46.8 58.5 92.5 43.0 92.1 34.8 52.6 37.9 38.5 74.6 48.7 23.7 33.9 78.0 35.0 101.1 58.5 56.8 51.1 30.1 30.6 34.1 38.8 29.6 32.2 34.4 32.5 34.4 32.1 32.1 35.1 67.5 102.5 40.9 12.7 79.1 124.8 91.6 129.4 51.8 17.2 60.7 43.9 66.7 44.3 80.7 40.5 31.3 179.8 93.0 168.6 101.8 95.4 51.7 75.6 55.3 62.9 45.5 70.4 9.9 102.1 176.2 67.7 37.8 63.0 57.0 35.7 46.4 35.5 131.3 8.4 9.4 49.7 103.7 59.1 183.9 15.3 37.0 97.3 83.6 15.9 129.0 49.8 41.2 14.6 18.0 137.6 132.5 40.6 92.2 98.2 85.6 125.2 107.7 35.0 46.0 56.3 101.1 44.1 32.1 74.6 127.9 508.5 94.8 36.6 54.5 120.3 UBE2B "HHR6B, RAD6B, UBC2" ENSG00000119048 "Ubiquitin conjugating enzyme E2 B" P63146 5 134371469-134392108 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 265.8" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 723.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 444.6" "Lineage enriched" "Detected in all" 6 "granulocytes: 444.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: AB_2667061, HPA051765: AB_2681597, HPA065898: AB_2685577" "unprognostic (1.98e-1)" "unprognostic (1.35e-1)" "unprognostic (7.39e-2)" "unprognostic (6.66e-2)" "unprognostic (1.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.56e-1)" "unprognostic (1.27e-1)" "unprognostic (1.91e-1)" "unprognostic (2.44e-1)" "unprognostic (2.49e-1)" "unprognostic (8.39e-2)" "unprognostic (1.64e-3)" "unprognostic (6.30e-3)" "unprognostic (3.42e-2)" "unprognostic (2.04e-1)" "unprognostic (5.52e-2)" 52.5 74.2 31.5 50.0 33.1 84.4 44.2 36.3 53.2 38.3 30.2 48.0 40.7 53.6 34.8 70.5 37.3 51.0 118.4 34.3 34.8 50.6 56.6 44.9 47.1 29.5 31.0 44.4 53.7 25.8 39.9 48.4 31.0 32.9 42.0 29.2 39.7 23.2 265.8 43.1 46.4 43.3 30.3 43.7 39.6 49.2 32.9 29.3 41.2 99.8 48.1 42.8 43.2 36.7 109.4 27.9 58.2 55.0 50.0 54.1 92.7 80.2 43.5 51.4 60.9 85.6 70.9 58.7 94.1 52.3 138.7 42.7 45.8 60.4 56.0 94.5 47.6 32.1 75.9 92.8 58.2 38.8 63.7 46.5 80.2 47.4 39.3 68.1 44.1 48.8 61.1 103.5 46.8 63.4 62.5 102.1 24.9 32.6 26.7 61.6 63.8 83.8 46.6 82.9 77.6 60.1 62.9 29.3 147.9 62.5 63.0 106.0 87.6 57.8 40.8 78.9 89.4 86.1 129.4 87.0 65.2 72.8 59.4 236.7 58.3 174.0 46.9 68.3 42.9 49.7 58.8 48.1 42.6 47.9 69.9 60.6 444.6 53.0 78.9 48.0 77.5 64.1 31.5 33.1 36.3 53.2 34.3 34.8 29.5 31.0 31.0 30.3 32.9 36.7 187.5 73.7 61.6 40.1 176.5 364.7 321.2 215.1 175.8 77.8 169.9 156.5 315.8 147.3 113.7 75.4 81.3 144.5 182.0 183.1 172.1 173.8 233.2 139.8 102.2 149.7 131.8 261.2 103.0 169.5 123.0 183.3 113.2 167.8 116.8 81.7 115.3 97.4 119.4 87.5 84.2 141.0 181.0 131.5 323.9 315.4 155.0 184.2 227.7 49.6 190.6 150.0 113.3 44.7 68.4 210.6 195.2 113.2 162.5 343.9 153.4 170.7 111.7 91.3 151.2 154.9 262.9 223.5 201.7 145.5 369.7 723.5 192.0 140.4 105.7 488.1 UBIAD1 "SCCD, TERE1" ENSG00000120942 "UbiA prenyltransferase domain containing 1" Q9Y5Z9 1 11273198-11296049 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Menaquinone biosynthesis, Ubiquinone biosynthesis" "Prenyltransferase, Transferase" "Corneal dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044862 Approved Vesicles NA NA "Cluster 30: Non-specific - Translation" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA044862: AB_2679117" "unprognostic (1.79e-2)" "unprognostic (2.26e-1)" "unprognostic (5.06e-2)" "unprognostic (1.74e-1)" "unprognostic (7.95e-3)" "unprognostic (7.55e-2)" "unprognostic (1.16e-2)" "unprognostic (2.01e-1)" "unprognostic (1.61e-1)" "unprognostic (2.55e-1)" "unprognostic (1.20e-1)" "unprognostic (1.63e-1)" "prognostic favorable (6.80e-5)" "unprognostic (3.00e-1)" "unprognostic (3.89e-1)" "unprognostic (2.03e-2)" "unprognostic (1.25e-1)" 7.3 7.5 5.5 7.6 7.5 7.6 8.3 6.9 7.0 6.8 2.3 7.0 5.5 8.4 6.1 5.9 9.6 4.6 8.2 5.2 6.1 6.5 10.1 6.1 10.2 7.5 7.5 11.5 10.8 10.0 5.8 6.4 6.8 7.1 6.8 8.0 7.0 6.6 17.7 8.1 6.4 7.9 6.6 7.1 7.2 9.2 7.1 11.9 7.7 13.8 10.5 8.1 5.6 10.1 14.5 14.1 11.0 21.3 8.0 7.4 14.8 15.6 12.7 16.4 14.9 16.4 13.1 28.5 15.6 11.1 15.4 19.5 28.1 18.7 19.9 20.0 24.1 19.1 14.5 22.0 14.5 29.5 15.9 11.2 24.9 22.2 26.3 8.7 12.2 25.8 23.1 22.9 11.2 14.8 19.1 14.7 13.3 27.1 20.7 18.0 24.6 34.6 12.7 9.5 13.6 14.5 16.6 16.3 21.5 4.5 12.1 15.3 10.2 14.4 15.5 15.1 20.5 18.6 27.9 52.4 9.2 38.3 18.3 11.5 12.8 19.5 24.3 17.5 27.3 45.3 32.5 24.8 16.9 42.1 48.5 33.3 3.9 20.5 15.6 21.1 33.8 22.2 5.5 7.5 6.9 7.0 5.2 6.1 7.5 7.5 6.8 6.6 7.1 10.1 9.4 9.6 14.6 4.2 19.6 15.4 16.7 11.2 22.2 11.9 13.3 13.7 8.3 11.5 18.1 5.5 8.4 10.6 17.5 7.4 11.7 10.8 34.1 6.3 9.6 9.5 4.9 13.3 4.2 13.3 14.7 11.4 13.3 9.6 7.0 11.3 7.9 19.7 8.7 13.5 6.5 11.1 14.2 8.2 14.1 23.1 12.5 9.5 5.4 4.7 7.1 9.5 14.4 9.0 11.1 11.0 5.3 10.9 14.2 15.0 5.8 8.6 8.9 15.8 0.0 20.2 10.4 24.7 15.7 15.7 12.6 18.9 14.4 12.0 14.1 10.3 UBR1 ENSG00000159459 "Ubiquitin protein ligase E3 component n-recognin 1" Q8IWV7 15 42942897-43106113 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 48.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 108.9;Inhibitory neurons: 108.8;Oligodendrocyte precursor cells: 102.1;Oligodendrocytes: 127.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038838, HPA038839" Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Vesicles "Nucleoplasm, Cytosol" "HPA038838: AB_10673120, HPA038839: " "unprognostic (1.07e-2)" "unprognostic (5.02e-2)" "unprognostic (9.77e-2)" "unprognostic (1.55e-2)" "unprognostic (1.89e-2)" "unprognostic (1.29e-1)" "unprognostic (2.67e-1)" "unprognostic (1.49e-1)" "unprognostic (4.79e-1)" "unprognostic (2.97e-2)" "unprognostic (1.93e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-3)" "unprognostic (5.78e-2)" "unprognostic (1.52e-1)" "unprognostic (2.00e-1)" "unprognostic (1.89e-1)" 9.1 7.9 12.5 8.8 29.4 24.9 9.3 11.7 17.4 9.9 4.8 8.6 7.8 10.7 7.4 5.8 8.0 8.6 13.7 11.6 31.5 9.2 7.1 8.6 10.9 24.2 18.3 7.7 9.5 14.3 6.6 10.5 21.6 10.0 8.0 14.3 6.3 10.5 12.0 5.6 7.8 9.6 8.5 9.5 7.2 10.1 21.2 13.3 12.6 14.0 8.7 9.1 5.8 48.6 7.4 10.2 11.6 9.6 17.1 14.7 10.7 17.6 19.4 15.9 19.2 13.3 5.5 8.6 10.1 18.4 18.9 12.4 17.1 15.5 18.1 18.0 8.4 33.1 20.4 6.3 12.3 23.0 14.4 15.3 8.4 18.8 14.8 14.6 17.0 16.7 19.6 12.3 18.7 4.5 12.7 6.8 6.5 18.9 10.6 16.4 15.7 6.4 14.9 16.6 12.0 10.3 22.7 12.0 7.7 13.1 10.9 12.2 24.3 17.9 11.1 16.7 18.0 14.6 26.4 23.6 12.2 14.6 16.6 3.7 1.5 2.5 2.4 1.8 2.9 1.9 2.6 2.9 1.4 2.3 2.6 3.2 2.9 3.2 1.7 2.2 1.9 0.9 12.5 29.4 11.7 17.4 11.6 31.5 24.2 18.3 21.6 8.5 21.2 48.6 46.4 48.1 30.7 73.1 28.9 10.6 11.6 9.3 17.1 27.5 15.4 10.8 28.0 12.8 19.1 9.2 27.1 14.7 35.8 12.8 0.0 10.8 16.8 13.4 27.4 24.5 14.4 23.8 108.9 14.4 7.7 25.6 20.9 18.2 28.5 22.8 17.2 9.9 8.1 32.0 108.8 10.9 14.2 16.4 10.6 16.9 16.1 17.1 8.8 73.1 15.6 13.5 23.7 102.1 127.6 10.3 8.2 20.7 33.2 7.7 12.3 9.2 15.7 38.8 13.1 34.7 36.5 27.0 17.8 8.6 7.2 36.9 31.4 16.5 10.6 9.8 UBTD1 FLJ11807 ENSG00000165886 "Ubiquitin domain containing 1" Q9HAC8 10 97498924-97571206 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 53.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 6.4;neutrophil: 6.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034825 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Plasma membrane, Cytosol" "HPA034825: AB_10602254" "unprognostic (1.52e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (5.54e-4)" "unprognostic (2.43e-1)" "unprognostic (1.78e-1)" "unprognostic (3.90e-2)" "unprognostic (3.63e-3)" "unprognostic (1.43e-2)" "unprognostic (1.66e-3)" "unprognostic (9.25e-3)" "unprognostic (2.45e-1)" "unprognostic (4.78e-1)" "unprognostic (6.62e-3)" "unprognostic (8.80e-2)" "unprognostic (1.49e-1)" "unprognostic (1.47e-3)" "unprognostic (3.50e-3)" 18.8 11.1 14.9 5.7 15.2 8.8 14.7 16.8 17.0 16.5 12.6 10.3 1.8 13.5 4.0 9.5 13.6 7.0 35.1 13.5 15.8 29.2 18.6 29.8 3.1 17.7 17.1 8.7 9.6 3.6 15.9 3.8 16.2 13.4 0.6 6.0 11.2 7.5 34.2 49.5 5.5 3.6 16.1 11.0 9.4 60.3 18.9 1.6 14.6 11.2 1.1 12.4 16.3 14.6 18.1 17.7 4.6 23.0 18.9 17.8 5.4 20.3 29.4 21.3 16.3 12.0 15.4 2.2 24.1 13.8 13.4 21.4 4.6 27.2 3.0 5.6 9.1 2.2 5.5 15.2 27.2 2.0 5.9 24.6 9.0 23.3 5.7 32.8 34.3 4.7 1.2 3.3 13.9 8.6 0.9 18.5 7.5 3.4 32.1 1.8 8.1 2.1 16.7 6.7 1.5 4.8 9.2 5.6 27.1 4.0 20.8 13.6 37.5 26.9 16.4 28.4 26.8 4.2 5.1 0.9 22.7 12.3 14.3 1.0 2.6 6.4 0.1 0.7 0.1 0.3 0.0 0.0 1.4 0.0 0.0 0.0 6.6 0.0 0.7 0.9 0.3 0.5 14.9 15.2 16.8 17.0 13.5 15.8 17.7 17.1 16.2 16.1 18.9 14.6 5.0 41.7 28.6 13.1 1.1 26.0 8.8 32.2 19.4 3.8 10.0 4.8 15.5 8.6 21.2 7.3 4.2 3.5 0.6 1.5 11.7 18.9 53.5 8.2 8.7 23.8 0.0 0.4 5.6 12.8 12.8 11.6 2.6 4.0 0.0 0.8 7.9 7.0 25.8 6.7 5.9 0.2 10.2 10.1 18.9 33.8 12.8 10.3 10.6 12.2 8.4 16.5 2.1 2.0 14.5 22.1 0.1 9.4 3.0 14.0 0.0 10.4 19.1 18.6 13.1 8.5 10.3 7.5 7.9 8.2 29.7 2.9 1.9 1.5 0.4 7.6 UCN2 "SRP, UCN-II, UCNI, URP" ENSG00000145040 "Urocortin 2" Q96RP3 3 48561718-48563781 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 13.1;vagina: 4.5" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2.9;Basal respiratory cells: 1.4" "Cancer enriched" "Detected in many" 5 "melanoma: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 18.8;hTCEpi: 27.3;hTEC/SVTERT24-B: 21.5;SiHa: 19.1;U-251 MG: 20.7;WM-115: 55.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA066841 Uncertain Approved Vesicles "Secreted to blood" NA NA 98600 "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA066841: AB_2685735" "unprognostic (7.98e-2)" "unprognostic (1.35e-1)" "unprognostic (4.80e-2)" "unprognostic (1.96e-2)" "unprognostic (2.39e-2)" "unprognostic (4.26e-2)" "unprognostic (1.92e-3)" "unprognostic (2.02e-3)" "unprognostic (1.62e-1)" "unprognostic (2.93e-3)" "unprognostic (2.52e-3)" "unprognostic (1.09e-1)" "unprognostic (3.34e-14)" "unprognostic (4.39e-2)" "unprognostic (2.75e-1)" "unprognostic (1.36e-1)" "unprognostic (2.88e-2)" 0.1 0.0 0.2 0.3 0.1 0.1 0.4 0.3 0.4 2.3 0.1 0.2 0.1 1.2 0.7 3.4 0.2 0.4 0.3 0.2 0.4 1.4 0.0 0.2 0.0 0.3 0.3 0.2 0.0 0.0 0.3 0.2 0.3 3.1 0.0 0.0 1.6 0.4 0.3 13.1 0.2 0.2 0.2 0.7 0.2 1.4 0.3 0.0 0.0 0.0 0.1 0.5 4.5 0.2 0.0 3.1 0.5 0.1 1.8 1.1 2.6 9.7 12.1 5.9 4.4 0.0 0.0 0.0 0.4 2.3 7.0 1.9 0.0 11.6 3.2 9.2 0.2 0.2 18.8 1.5 2.0 0.0 0.5 1.3 27.3 21.5 4.3 4.1 0.0 0.2 0.0 0.2 0.9 0.0 0.0 1.8 0.8 0.0 0.2 0.2 0.3 0.0 1.8 0.0 0.0 0.0 19.1 0.0 14.5 1.7 0.3 0.4 0.0 2.6 1.8 0.3 20.7 0.1 0.3 0.0 8.8 0.1 55.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.4 0.2 0.4 0.3 0.3 0.3 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 2.9 0.3 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 UGT1A6 "GNT1, HLUGP, UGT1F" ENSG00000167165 "UDP glucuronosyltransferase family 1 member A6" P19224 2 233691607-233773300 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 71.3;liver: 143.3;urinary bladder: 88.8" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 12.5;Early spermatids: 52.4;Gastric mucus-secreting cells: 14.3;Late spermatids: 23.3;Squamous epithelial cells: 17.3" "Group enriched" "Detected in many" 5 "liver cancer: 7.2;lung cancer: 3.1;renal cancer: 7.6;urothelial cancer: 3.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "OE19: 1194.0" "Not detected" "Not detected" "CAB009819, HPA054065, HPA056023" Enhanced Supported "Endoplasmic reticulum,Vesicles" NA NA "Cluster 85: Liver - Metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" Vesicles "Endoplasmic reticulum" "CAB009819: AB_2241481, HPA054065: AB_2682367, HPA056023: " "unprognostic (9.09e-2)" "unprognostic (6.07e-2)" "unprognostic (5.43e-2)" "unprognostic (6.03e-2)" "prognostic unfavorable (2.89e-6)" "unprognostic (2.79e-1)" "unprognostic (6.18e-2)" "unprognostic (2.09e-3)" "unprognostic (9.97e-2)" "unprognostic (2.16e-2)" "unprognostic (3.52e-1)" "unprognostic (7.50e-2)" "unprognostic (2.01e-2)" 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 1.8 0.0 1.8 5.8 0.1 2.6 16.1 0.0 3.5 0.0 0.0 0.0 71.3 143.3 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 1.1 1.3 0.0 2.6 3.6 0.0 11.1 2.6 0.0 0.0 0.0 17.4 0.4 0.0 1.2 0.5 0.0 5.8 88.8 5.5 0.0 4.2 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 53.8 1.6 0.0 80.2 0.1 0.8 294.5 0.1 4.0 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.3 0.0 31.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 6.2 0.0 0.0 0.0 1194.0 0.0 0.1 0.2 0.1 3.2 149.0 0.0 0.0 7.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.6 1.2 12.5 0.0 0.0 0.0 0.3 0.0 2.9 1.8 0.0 0.0 0.0 0.4 0.0 0.0 52.4 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 14.3 0.5 0.0 0.0 0.4 5.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 23.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.5 1.8 0.1 0.0 0.0 0.0 0.0 1.2 0.2 17.3 1.1 0.0 0.0 0.0 0.1 3.0 UGT3A1 FLJ34658 ENSG00000145626 "UDP glycosyltransferase family 3 member A1" Q6NUS8 5 35951006-36001028 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "kidney: 51.1;liver: 58.0" "Cell type enhanced" "Detected in some" "Collecting duct cells: 49.7;Early spermatids: 125.9;Hepatocytes: 72.1;Late spermatids: 24.5;Proximal tubular cells: 87.0" "Group enriched" "Detected in some" 15 "liver cancer: 6.7;renal cancer: 4.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 42 "RH-30: 28.2" "HPA047697, HPA056290" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Cytosol" "HPA047697: AB_2680122, HPA056290: AB_2683088" "unprognostic (2.41e-3)" "unprognostic (4.47e-1)" "unprognostic (4.04e-1)" "unprognostic (4.62e-1)" "unprognostic (1.42e-2)" "unprognostic (6.05e-2)" "unprognostic (9.14e-2)" "unprognostic (1.76e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 51.1 58.0 0.0 0.0 0.1 0.0 0.2 0.0 0.4 0.2 0.0 0.1 0.3 0.0 0.7 0.1 0.2 3.0 0.0 6.7 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.4 0.0 0.0 49.7 0.0 0.0 0.0 0.0 3.9 0.0 125.9 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.8 72.1 0.1 0.0 0.3 0.7 0.0 2.6 0.0 24.5 0.9 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 2.5 0.4 0.0 0.0 3.8 87.0 0.0 0.2 6.6 0.0 0.0 4.4 0.8 0.0 0.0 0.0 0.5 0.0 1.8 0.1 UHMK1 "KIS, Kist" ENSG00000152332 "U2AF homology motif kinase 1" Q8TAS1 1 162497251-162529631 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077624 Supported "Nucleoplasm,Nuclear speckles,Vesicles" NA No "Cluster 51: Monocytes - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" Vesicles "HPA077624: " "unprognostic (6.69e-2)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.46e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.08e-2)" "unprognostic (8.16e-2)" "unprognostic (9.63e-2)" "unprognostic (1.82e-1)" "unprognostic (7.81e-3)" "unprognostic (9.10e-2)" "unprognostic (3.11e-1)" "unprognostic (3.44e-2)" "unprognostic (9.08e-2)" "unprognostic (8.77e-2)" "unprognostic (4.66e-2)" 26.8 23.3 21.2 23.3 24.6 40.3 19.3 18.1 21.2 15.1 16.6 19.2 19.1 11.7 14.1 13.3 14.4 13.7 11.6 26.0 28.3 31.2 38.1 17.5 30.8 24.9 28.5 11.9 11.0 27.8 7.8 17.1 28.3 16.2 19.6 10.5 13.5 18.5 25.8 11.9 23.4 10.8 19.8 25.4 20.0 12.2 26.1 24.6 19.4 25.9 28.9 18.1 10.5 19.4 61.9 28.4 14.6 35.8 40.7 31.9 32.7 79.7 43.2 63.9 45.7 18.6 37.8 50.2 67.8 60.0 31.2 34.9 28.2 44.1 102.4 69.1 20.4 49.8 34.3 16.9 31.3 73.4 55.5 33.0 45.8 63.2 59.9 44.6 37.4 34.2 44.1 67.7 111.4 26.0 39.3 19.4 19.4 46.1 37.8 24.9 64.9 41.9 42.6 62.8 26.4 24.3 70.5 64.6 52.2 19.9 56.0 81.0 58.5 72.7 41.0 50.8 112.6 69.2 103.5 58.0 60.5 35.3 67.3 3.6 2.0 2.4 4.8 5.3 4.9 3.2 3.5 4.0 2.3 3.6 3.5 4.0 1.3 3.7 6.1 2.6 3.1 2.6 21.2 24.6 18.1 21.2 26.0 28.3 24.9 28.5 28.3 19.8 26.1 19.4 37.6 19.2 41.2 20.9 75.6 29.4 33.7 38.5 34.7 24.4 39.4 20.2 35.1 40.0 53.8 53.3 12.5 26.2 81.0 53.9 56.7 27.6 55.6 35.1 35.7 33.4 33.5 51.6 37.0 23.2 38.1 25.5 43.3 44.4 45.7 23.3 31.1 85.1 30.0 23.5 27.4 34.1 48.8 73.5 47.5 58.4 21.5 60.0 28.4 33.7 58.0 14.6 74.2 20.6 29.5 40.4 33.0 19.5 47.2 59.9 60.8 62.2 50.9 23.0 0.0 29.2 27.8 25.1 29.6 45.2 24.6 22.4 69.4 31.4 39.3 58.3 UHRF1BP1L KIAA0701 ENSG00000111647 "UHRF1 binding protein 1 like" A0JNW5 12 100028455-100142874 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 75.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039671, HPA075150" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Vesicles, Cytosol" "HPA039671: AB_10794201, HPA075150: " "unprognostic (4.80e-2)" "unprognostic (3.17e-1)" "unprognostic (2.34e-2)" "unprognostic (1.14e-1)" "unprognostic (8.96e-2)" "unprognostic (7.36e-2)" "unprognostic (8.10e-2)" "unprognostic (5.75e-3)" "unprognostic (2.06e-1)" "unprognostic (5.43e-2)" "unprognostic (1.88e-2)" "unprognostic (2.53e-1)" "unprognostic (2.94e-3)" "unprognostic (6.84e-2)" "unprognostic (1.25e-1)" "unprognostic (3.81e-2)" "unprognostic (1.28e-2)" 8.7 10.9 6.2 10.2 7.7 32.9 8.8 11.0 11.5 7.2 9.9 8.3 8.4 7.5 7.0 7.0 6.3 8.9 7.9 13.2 6.2 12.3 24.6 7.7 9.2 4.9 5.4 7.5 3.8 13.6 5.2 9.0 4.8 9.0 7.9 14.6 6.4 8.0 19.8 5.9 7.1 8.8 4.6 9.2 6.0 14.0 3.7 8.4 10.9 14.6 7.0 10.1 5.2 9.2 18.6 19.7 10.8 11.2 16.4 23.1 21.6 28.3 28.4 22.4 16.3 14.8 6.2 16.0 7.2 29.1 13.1 6.9 20.4 9.7 21.5 42.7 10.0 10.7 14.1 17.3 15.1 20.4 16.8 13.1 8.0 27.0 18.6 20.7 16.0 11.0 8.6 16.2 22.1 10.3 13.1 17.5 18.7 6.3 17.7 14.7 19.2 15.7 11.4 32.2 18.3 11.4 21.4 24.5 8.5 9.2 21.9 23.0 12.7 24.6 13.2 21.5 20.1 19.1 35.2 22.3 12.4 15.1 15.2 21.6 11.4 7.8 3.6 12.3 5.3 5.5 4.0 4.1 12.8 4.5 3.4 4.2 33.9 5.9 10.9 7.6 5.2 5.4 6.2 7.7 11.0 11.5 13.2 6.2 4.9 5.4 4.8 4.6 3.7 9.2 10.6 28.9 8.7 27.1 18.2 12.7 17.2 5.0 19.9 11.9 9.3 7.5 15.7 1.5 12.6 9.2 4.2 4.7 15.0 10.9 5.9 6.0 35.1 15.7 23.7 8.6 5.4 9.4 75.2 5.9 8.9 24.7 7.7 9.9 24.1 6.3 5.3 18.5 11.2 15.2 54.2 2.1 4.1 23.3 21.4 5.3 7.2 29.5 10.6 45.0 25.7 8.3 8.2 37.2 29.5 5.9 7.4 7.9 12.5 18.5 8.9 14.9 21.8 12.0 0.0 23.3 15.1 24.1 19.1 14.9 11.6 10.9 15.7 8.3 5.7 11.9 ULBP2 RAET1H ENSG00000131015 "UL16 binding protein 2" Q9BZM5 6 149942014-149949235 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 6.1" "Cell type enhanced" "Detected in many" "Adipocytes: 28.9;Basal respiratory cells: 17.9;dendritic cells: 12.1" "Cancer enhanced" "Detected in all" "head and neck cancer: 12.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.7" "Lineage enriched" "Detected in single" 6 "T-cells: 2.7" "Cell line enhanced" "Detected in many" "SiHa: 66.7;U-2197: 47.4" "CAB018974, HPA066741" Approved Supported "Vesicles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 27: Brain & Skin - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Plasma membrane" "CAB018974: , HPA066741: " "unprognostic (2.09e-5)" "prognostic unfavorable (8.07e-4)" "unprognostic (2.38e-3)" "unprognostic (3.90e-1)" "prognostic unfavorable (2.44e-4)" "unprognostic (1.26e-2)" "unprognostic (2.38e-3)" "unprognostic (1.47e-1)" "unprognostic (1.02e-1)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (1.75e-2)" "unprognostic (1.42e-4)" "unprognostic (1.68e-1)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (4.86e-1)" 1.5 0.7 1.3 0.6 1.6 1.8 0.7 1.6 2.6 0.9 0.7 0.2 0.2 0.1 0.1 6.1 0.2 0.5 2.0 3.0 1.0 2.1 0.5 3.4 0.3 1.8 1.2 0.0 0.4 0.6 0.5 1.6 1.8 0.2 0.1 0.2 0.7 0.1 0.3 0.5 0.2 0.7 0.8 0.2 0.3 1.5 1.1 0.7 1.2 0.7 0.8 1.4 1.6 1.7 19.9 1.8 0.5 6.1 1.1 5.6 3.3 20.1 11.8 20.6 16.8 7.4 11.0 0.0 29.9 23.0 29.6 13.9 7.6 18.4 11.8 9.1 3.9 1.1 2.8 0.0 7.1 0.0 1.5 2.7 13.9 18.3 8.0 16.7 11.9 16.6 2.5 0.0 15.4 13.9 1.8 0.0 0.0 3.6 10.2 3.0 4.5 0.0 29.0 5.7 0.6 0.0 66.7 1.4 1.9 3.2 1.8 8.5 18.8 13.5 17.1 47.4 23.5 0.0 0.1 0.9 19.2 10.7 9.9 0.0 0.0 0.0 2.7 0.0 0.3 0.0 0.8 1.5 0.0 0.0 0.3 1.8 0.0 0.4 0.0 0.0 1.7 0.5 1.3 1.6 1.6 2.6 3.0 1.0 1.8 1.2 1.8 0.8 1.1 1.7 28.9 0.0 1.3 0.0 1.2 3.7 6.5 17.9 7.4 0.0 1.3 4.4 0.3 0.0 9.4 1.8 0.0 0.0 12.1 0.5 0.0 7.5 7.0 0.3 0.5 9.1 0.0 0.0 3.0 8.8 0.5 3.0 1.1 0.2 0.0 0.1 7.1 0.2 2.2 0.0 0.7 0.3 2.0 0.8 2.1 8.0 0.0 3.1 1.8 0.0 0.0 0.4 4.1 0.5 0.3 4.5 0.0 0.0 1.4 1.4 0.0 0.1 1.4 0.0 0.0 1.0 4.2 3.1 7.0 11.8 2.8 0.0 11.0 0.6 0.4 5.2 ULBP3 RAET1N ENSG00000131019 "UL16 binding protein 3" Q9BZM4 6 150061053-150069121 "Predicted intracellular proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 6.5;testis: 6.3" "Cell type enhanced" "Detected in single" "Gastric mucus-secreting cells: 1.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA056541, HPA063007" Approved Uncertain "Vesicles,Centriolar satellite" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 18: U-2197 - ECM organization" "Cluster 59: Non-specific - Transcription" Vesicles "Centriolar satellite" "HPA056541: , HPA063007: AB_2684920" "unprognostic (4.87e-2)" "unprognostic (4.49e-2)" "unprognostic (3.14e-3)" "unprognostic (1.50e-2)" "unprognostic (1.86e-2)" "unprognostic (2.99e-2)" "unprognostic (8.47e-2)" "unprognostic (1.96e-1)" "unprognostic (5.87e-2)" "unprognostic (8.71e-2)" "unprognostic (1.66e-2)" "unprognostic (3.54e-2)" "unprognostic (6.26e-2)" "unprognostic (3.43e-1)" "unprognostic (2.12e-1)" "unprognostic (5.45e-2)" "unprognostic (5.16e-2)" 1.3 1.2 1.6 0.7 1.8 0.7 1.0 1.6 2.4 0.5 0.4 0.8 1.1 1.0 0.9 1.5 2.0 1.3 0.7 1.7 1.4 1.7 1.0 1.5 0.5 0.9 0.9 0.8 0.7 0.9 0.1 0.9 0.9 0.7 0.8 0.8 0.4 0.5 6.5 1.1 0.5 0.5 0.2 0.6 1.9 6.3 1.3 0.5 4.9 0.4 0.9 1.0 0.5 1.9 6.2 2.0 6.5 7.3 1.6 11.9 2.3 6.1 2.6 7.2 8.0 11.0 5.1 0.2 11.8 9.9 10.9 8.3 17.7 20.5 7.7 3.7 7.8 0.6 2.9 0.5 2.5 0.1 1.1 10.2 3.5 15.0 8.1 6.9 9.7 0.2 0.5 0.8 6.3 7.0 0.3 0.5 3.1 2.6 14.8 6.2 5.9 0.3 17.5 12.4 1.2 0.5 12.2 8.2 3.0 3.4 2.5 1.7 5.6 1.2 9.8 20.5 13.3 0.3 0.2 4.1 9.6 3.7 5.1 0.8 0.2 0.2 2.2 0.2 2.9 0.8 1.5 2.4 0.2 0.5 0.8 1.2 1.0 0.6 0.2 0.3 2.3 0.4 1.6 1.8 1.6 2.4 1.7 1.4 0.9 0.9 0.9 0.2 1.3 1.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.0 UNC13B "hmunc13, Munc13-2, UNC13, Unc13h2" ENSG00000198722 "Unc-13 homolog B" O14795 9 35161992-35405338 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Alveolar cells type 2: 80.7;Cone photoreceptor cells: 95.9;Excitatory neurons: 60.4;Microglial cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024493, HPA062300" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles,Intermediate filaments" Yes No "Cluster 77: Retina - Visual perception" "Cluster 21: OE19 - Mitochondria" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "Nucleoplasm, Golgi apparatus, Intermediate filaments" "HPA024493: AB_1858618, HPA062300: AB_2684742" "unprognostic (9.73e-3)" "unprognostic (2.33e-1)" "prognostic favorable (4.96e-4)" "unprognostic (6.56e-2)" "unprognostic (9.93e-2)" "prognostic favorable (8.51e-5)" "unprognostic (7.64e-2)" "prognostic favorable (6.59e-5)" "unprognostic (3.80e-1)" "unprognostic (1.64e-1)" "prognostic favorable (3.71e-4)" "unprognostic (1.74e-1)" "prognostic favorable (4.34e-11)" "unprognostic (2.40e-1)" "unprognostic (1.89e-1)" "unprognostic (1.48e-1)" "unprognostic (2.80e-2)" 12.6 12.8 10.5 5.6 13.3 1.0 10.3 6.6 14.5 12.5 15.7 22.2 11.6 10.1 7.7 17.5 10.4 11.5 13.6 11.4 7.2 21.8 12.8 38.9 1.8 8.3 9.5 7.3 21.3 15.0 11.5 6.0 7.8 22.6 25.0 41.2 17.8 23.3 24.2 12.3 13.4 11.9 7.3 4.7 17.9 15.6 10.6 3.0 12.2 10.4 5.0 10.2 12.7 9.0 9.8 12.8 13.9 22.6 26.3 14.6 11.8 15.7 7.1 11.4 15.3 10.7 4.5 0.0 7.0 20.6 20.1 4.7 35.4 18.2 14.5 0.0 11.3 5.9 36.6 13.9 12.7 2.2 6.4 11.6 14.0 18.0 18.5 18.2 37.3 15.8 13.5 8.1 13.5 7.5 2.1 0.2 12.6 30.2 13.3 0.1 8.6 3.4 15.5 12.6 14.9 15.7 11.0 6.8 11.4 23.0 11.6 7.5 34.5 7.8 7.2 12.3 12.2 12.7 16.2 0.0 8.5 18.4 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 13.3 6.6 14.5 11.4 7.2 8.3 9.5 7.8 7.3 10.6 9.0 6.7 57.7 80.7 28.7 0.8 3.1 1.1 2.1 3.4 42.3 7.3 4.4 11.4 18.6 16.7 9.2 95.9 3.7 0.1 24.4 3.9 6.0 6.9 8.2 5.1 8.5 24.6 1.7 60.4 12.2 2.1 4.8 16.3 13.9 2.5 8.7 5.7 12.5 4.9 6.7 17.7 31.9 0.0 2.4 3.0 12.3 2.1 3.7 7.2 73.1 0.1 5.7 0.0 42.3 36.7 7.8 11.9 3.0 4.2 11.7 10.5 7.8 10.0 40.8 6.6 8.4 6.5 8.7 7.5 14.3 7.4 2.9 1.0 5.7 19.5 5.7 UNC13D Munc13-4 ENSG00000092929 "Unc-13 homolog D" Q70J99 17 75827225-75844552 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Exocytosis "Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.9;lymphoid tissue: 66.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 68.3;Hofbauer cells: 58.5;NK-cells: 61.8;Pancreatic endocrine cells: 47.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 245.7;HeLa: 136.3;HMC-1: 245.9;SK-BR-3: 189.7" "Region enriched" "Detected in single" 6 "cerebellum: 5.0" "Low region specificity" "Detected in many" "HPA067117, HPA073525" Enhanced Supported Vesicles,Cytosol NA NA 1500000 "Cluster 38: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol Vesicles "HPA067117: AB_2685784, HPA073525: AB_2686615" "unprognostic (6.79e-3)" "unprognostic (4.36e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.62e-4)" "unprognostic (2.98e-2)" "unprognostic (1.42e-3)" "unprognostic (3.93e-1)" "unprognostic (1.37e-2)" "unprognostic (2.74e-1)" "unprognostic (1.31e-2)" "prognostic unfavorable (6.01e-4)" "unprognostic (1.89e-1)" "prognostic unfavorable (5.28e-12)" "unprognostic (3.27e-2)" "unprognostic (5.58e-2)" "unprognostic (1.56e-1)" "unprognostic (8.59e-2)" 7.7 7.3 5.6 23.5 6.8 58.9 7.8 5.8 7.3 18.6 5.0 10.7 8.0 8.6 2.0 23.6 13.8 6.5 14.3 5.0 5.6 6.6 12.6 38.1 25.9 7.9 6.5 19.3 8.8 0.5 11.6 9.0 7.5 8.1 4.5 5.5 7.7 5.1 8.5 6.0 18.5 4.9 6.2 66.2 13.8 6.1 8.2 20.7 5.9 1.5 17.6 10.7 19.6 8.7 44.0 18.7 0.4 0.3 0.5 1.0 47.6 0.1 0.0 0.0 0.1 41.4 97.0 3.4 46.4 0.0 7.5 15.4 0.0 2.2 0.0 0.4 0.5 245.7 136.3 24.2 3.9 94.1 245.9 0.6 2.0 0.5 2.1 2.3 17.9 42.5 87.1 1.1 0.0 71.2 100.9 50.8 0.9 69.9 1.7 32.8 1.0 1.5 1.6 17.7 0.3 66.7 19.2 189.7 0.9 0.5 47.1 56.5 48.1 0.8 65.9 0.5 0.5 1.3 5.9 4.0 0.6 31.3 0.2 59.1 16.0 31.2 19.3 16.9 17.4 6.7 11.4 13.6 12.3 3.6 8.8 11.9 40.1 14.7 25.6 7.2 10.8 18.1 5.6 6.8 5.8 7.3 5.0 5.6 7.9 6.5 7.5 6.2 8.2 8.7 3.8 44.8 8.3 6.8 16.6 1.1 1.7 1.0 0.6 12.0 4.9 2.4 68.3 7.2 4.4 3.7 20.9 4.7 27.0 40.9 0.0 7.2 5.3 1.3 3.3 6.6 6.0 14.9 1.2 6.0 11.6 2.2 2.0 2.3 45.0 9.9 7.9 1.2 58.5 5.0 1.5 3.6 2.0 21.6 8.2 0.5 2.8 22.2 1.8 5.6 22.5 4.5 61.8 3.0 7.9 47.3 30.7 1.5 27.4 1.6 5.5 0.7 1.6 16.2 0.0 4.5 2.6 1.2 1.4 1.5 1.4 25.9 30.9 2.0 6.3 2.3 UNC80 "C2orf21, FLJ33496, KIAA1843, UNC-80" ENSG00000144406 "Unc-80 homolog, NALCN channel complex subunit" Q8N2C7 2 209771832-209999300 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 21.0;pituitary gland: 13.6;retina: 18.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 117.7;Excitatory neurons: 432.0;Inhibitory neurons: 354.7;Oligodendrocyte precursor cells: 290.5" "Cancer enhanced" "Detected in some" "glioma: 0.8;prostate cancer: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 2.5;SCLC-21H: 4.0;SH-SY5Y: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042472, HPA050959" Enhanced Approved "Nuclear bodies,Vesicles" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear bodies" Vesicles "HPA042472: AB_10965318, HPA050959: " "unprognostic (7.91e-3)" "unprognostic (2.25e-4)" "unprognostic (1.44e-2)" "unprognostic (3.20e-4)" "unprognostic (1.92e-1)" "unprognostic (3.40e-2)" "unprognostic (3.31e-3)" "unprognostic (5.36e-2)" "unprognostic (5.16e-1)" "unprognostic (7.85e-2)" "unprognostic (5.24e-3)" "unprognostic (8.94e-2)" "unprognostic (1.50e-2)" "unprognostic (1.51e-2)" "unprognostic (6.50e-2)" "unprognostic (1.95e-1)" "unprognostic (7.40e-3)" 0.0 3.9 6.4 0.0 9.9 0.0 0.0 15.6 21.0 0.0 0.0 0.2 0.0 0.1 0.4 0.0 0.4 1.1 0.0 6.9 4.9 0.1 0.0 0.1 0.0 6.7 1.5 0.5 1.0 0.2 13.6 0.0 5.8 0.9 0.1 18.9 0.1 0.2 0.0 0.1 0.1 0.2 1.1 0.2 0.4 3.5 2.6 0.1 0.3 0.0 0.0 0.2 0.0 5.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.5 0.0 0.0 0.0 4.0 2.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 9.9 15.6 21.0 6.9 4.9 6.7 1.5 5.8 1.1 2.6 5.0 0.2 0.0 1.1 49.0 0.0 0.8 0.3 1.9 0.0 117.7 0.2 0.1 2.1 0.0 0.7 0.0 66.7 0.0 0.0 0.0 0.0 0.0 31.9 1.1 1.7 0.5 0.0 0.0 432.0 0.0 0.0 1.1 0.0 0.1 1.3 0.6 0.0 0.0 0.1 52.2 354.7 0.0 0.0 0.0 0.0 10.5 0.9 0.3 0.0 10.3 0.0 26.6 0.0 290.5 12.8 0.1 0.0 1.9 0.0 1.2 0.0 0.2 0.8 75.6 0.0 0.2 0.1 7.5 3.8 0.0 0.1 0.0 0.0 15.1 0.0 0.3 UPF3A "HUPF3A, RENT3A, UPF3" ENSG00000169062 "UPF3A regulator of nonsense mediated mRNA decay" Q9H1J1 13 114281601-114305817 "Predicted intracellular proteins" "mRNA transport, Nonsense-mediated mRNA decay, Transport" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 480.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018325, HPA061316" Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 6: Non-specific - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Vesicles, Cytosol" "HPA018325: AB_1858638, HPA061316: AB_2684477" "unprognostic (9.08e-3)" "unprognostic (1.99e-1)" "unprognostic (1.93e-1)" "unprognostic (3.43e-2)" "unprognostic (2.51e-2)" "unprognostic (1.16e-2)" "unprognostic (6.48e-2)" "unprognostic (1.98e-1)" "unprognostic (9.80e-3)" "unprognostic (1.44e-1)" "prognostic favorable (7.09e-5)" "unprognostic (1.39e-3)" "unprognostic (1.52e-2)" "unprognostic (2.34e-2)" "unprognostic (9.21e-3)" "unprognostic (1.76e-1)" "prognostic favorable (3.71e-4)" 17.5 20.0 13.7 15.1 14.6 18.0 16.4 19.6 19.7 17.6 10.2 17.4 18.1 18.7 8.3 13.3 18.4 11.7 12.9 12.9 16.9 14.5 10.3 12.1 17.0 16.4 14.6 15.5 19.7 13.7 17.1 11.2 17.3 16.4 11.1 11.6 16.5 14.5 23.8 15.6 15.9 11.3 13.2 16.3 16.7 46.3 14.3 17.9 30.2 7.5 10.8 15.4 14.3 17.5 55.9 15.9 35.3 31.7 16.4 28.1 22.3 42.0 30.0 26.4 29.1 24.4 19.4 54.0 11.9 19.6 17.8 29.3 17.2 14.1 32.6 39.8 33.7 47.0 50.9 27.1 28.3 81.7 20.3 19.1 28.1 17.8 20.5 27.7 21.2 14.0 29.0 24.7 26.6 16.7 33.8 22.1 46.7 36.8 15.9 43.2 19.8 31.7 23.4 17.5 39.1 43.3 33.6 51.3 31.3 23.6 37.6 72.7 27.5 27.8 46.0 15.5 26.6 53.4 39.3 74.5 51.7 46.7 23.3 3.0 5.6 4.8 6.8 4.7 5.2 13.2 7.0 7.2 6.5 9.7 7.1 6.7 0.9 11.9 6.1 16.9 10.8 4.3 13.7 14.6 19.6 19.7 12.9 16.9 16.4 14.6 17.3 13.2 14.3 17.5 104.8 67.3 61.5 88.5 64.2 68.7 57.8 57.2 76.8 85.3 80.6 84.3 22.8 52.9 60.8 58.8 83.4 65.0 75.3 32.1 103.7 54.3 205.8 148.7 101.2 78.1 57.5 51.9 84.7 71.2 45.2 69.7 42.8 65.4 55.6 57.7 63.9 72.6 45.7 79.1 114.7 50.5 79.3 44.9 46.1 96.8 100.6 53.8 55.2 59.0 51.1 74.2 83.4 188.5 130.9 52.6 34.0 87.6 81.1 59.1 36.0 69.8 96.0 72.3 85.5 77.5 56.4 480.3 172.4 82.4 71.9 40.5 64.3 111.8 62.2 46.7 UPP2 "UDRPASE2, UP2, UPASE2" ENSG00000007001 "Uridine phosphorylase 2" O95045 2 157876702-158136154 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "kidney: 45.8;liver: 23.9" "Cell type enhanced" "Detected in some" "Astrocytes: 24.2;Distal tubular cells: 13.7;Excitatory neurons: 32.5;Inhibitory neurons: 20.8;Oligodendrocyte precursor cells: 27.6;Proximal tubular cells: 82.1" "Cancer enriched" "Detected in some" 6 "liver cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA035225, HPA035226" Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Vesicles, Mitochondria" "HPA035225: AB_10604002, HPA035226: AB_10696503" "unprognostic (1.87e-1)" "unprognostic (2.33e-1)" "unprognostic (4.22e-3)" "unprognostic (1.36e-3)" "unprognostic (2.29e-1)" "unprognostic (1.55e-1)" "unprognostic (3.53e-2)" "unprognostic (5.51e-2)" "unprognostic (5.11e-2)" "unprognostic (1.23e-2)" "unprognostic (4.65e-3)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (4.89e-2)" "unprognostic (2.78e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-2)" 0.0 0.1 3.3 0.0 2.9 0.0 0.0 1.8 3.0 0.1 1.4 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 3.7 1.9 45.8 23.9 0.0 0.1 1.3 1.3 0.3 0.1 0.0 0.2 0.0 1.1 0.0 0.0 0.9 0.4 0.0 0.0 0.3 0.1 0.0 1.4 0.0 0.0 0.1 1.6 0.0 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 2.9 1.8 3.0 3.7 1.9 1.3 1.3 1.1 1.4 1.6 2.4 0.0 0.0 0.0 24.2 0.2 0.0 0.1 0.0 0.0 1.3 0.1 0.3 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 13.7 0.0 0.1 0.2 0.1 0.1 0.0 0.0 32.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.1 8.2 0.0 0.0 20.8 0.0 0.0 0.9 0.0 0.1 0.3 0.5 0.0 2.8 0.0 0.1 0.0 27.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 82.1 0.0 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 UPRT "DKFZp781E1243, FUR1, MGC23937, RP11-311P8.3" ENSG00000094841 "Uracil phosphoribosyltransferase homolog" Q96BW1 X 75156388-75304885 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000805 Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 3: T-cells - Adaptive immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm Vesicles "HPA000805: AB_1080482" "unprognostic (3.12e-3)" "unprognostic (5.85e-2)" "unprognostic (1.40e-1)" "unprognostic (2.67e-2)" "unprognostic (2.43e-1)" "unprognostic (1.18e-2)" "unprognostic (4.62e-2)" "unprognostic (1.04e-3)" "unprognostic (9.64e-2)" "unprognostic (1.37e-2)" "unprognostic (1.05e-2)" "unprognostic (2.62e-1)" "prognostic favorable (4.14e-4)" "unprognostic (6.09e-2)" "unprognostic (2.54e-2)" "unprognostic (2.74e-1)" "unprognostic (4.53e-3)" 6.2 10.9 7.2 6.3 7.4 13.4 7.9 7.4 8.7 8.1 8.1 7.6 10.9 5.9 8.9 7.9 7.2 6.1 9.3 7.1 8.2 11.4 8.6 7.6 8.9 7.2 8.3 6.1 6.5 14.0 7.0 5.8 7.9 9.2 7.9 6.4 8.7 6.0 8.9 5.6 8.1 6.5 7.4 7.3 10.3 1.9 8.1 8.9 10.2 10.8 8.2 6.9 4.7 8.1 11.6 7.6 8.9 8.1 9.4 9.9 8.4 8.0 9.2 8.4 9.6 7.2 7.7 16.3 6.6 8.5 15.1 4.8 20.7 6.8 13.9 14.3 8.0 10.2 7.8 9.1 9.0 20.2 20.1 7.5 5.0 11.2 6.1 13.4 15.1 13.1 12.1 15.7 22.6 4.8 22.7 12.4 17.8 8.6 13.0 10.7 22.8 8.1 21.9 6.4 0.6 9.2 11.0 11.4 11.4 15.7 5.3 12.6 12.6 10.6 6.3 19.4 6.8 10.7 36.5 15.8 11.2 21.9 6.9 6.9 7.3 9.2 7.7 10.6 9.0 8.2 7.6 8.0 10.9 7.0 9.4 8.3 1.4 14.4 17.9 5.2 13.5 7.1 7.2 7.4 7.4 8.7 7.1 8.2 7.2 8.3 7.9 7.4 8.1 8.1 8.5 6.4 5.0 8.1 8.0 6.2 8.7 10.0 3.4 8.5 5.3 3.8 6.6 5.7 11.2 9.2 0.0 8.4 8.1 5.3 27.4 8.8 2.0 4.8 4.1 8.6 6.0 4.6 8.8 6.0 15.1 5.2 5.1 4.1 24.1 5.2 11.7 6.0 11.6 10.1 8.8 5.3 22.4 16.1 8.8 1.8 4.4 10.8 14.2 3.7 7.8 9.4 13.4 13.0 8.4 5.6 3.2 3.4 9.8 5.5 8.4 15.4 6.1 7.2 6.6 4.8 7.1 0.7 2.4 4.2 6.0 12.2 12.1 6.5 7.2 7.4 URM1 "C9orf74, MGC2668" ENSG00000167118 "Ubiquitin related modifier 1" Q9BTM9 9 128371361-128392016 "Predicted intracellular proteins" "tRNA processing, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053645, HPA065160" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 35: T-regs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Vesicles Nucleoplasm "HPA053645: AB_2682215, HPA065160: AB_2685423" "unprognostic (7.42e-2)" "unprognostic (1.69e-2)" "unprognostic (2.42e-1)" "unprognostic (8.94e-3)" "unprognostic (1.53e-1)" "unprognostic (1.59e-1)" "prognostic unfavorable (6.91e-4)" "unprognostic (3.04e-2)" "unprognostic (9.19e-2)" "unprognostic (5.61e-3)" "unprognostic (2.39e-2)" "unprognostic (2.36e-1)" "prognostic favorable (7.43e-6)" "unprognostic (1.77e-3)" "unprognostic (1.93e-1)" "unprognostic (2.47e-1)" "unprognostic (6.17e-2)" 20.1 23.8 35.5 16.3 40.3 26.2 20.0 37.7 37.8 21.2 28.1 22.0 20.2 21.2 15.1 22.0 18.8 11.2 31.1 33.8 35.9 26.8 24.6 17.6 21.7 40.3 41.2 19.5 30.0 18.9 17.9 14.7 38.0 22.7 16.5 12.4 17.2 14.1 25.2 20.9 20.8 16.8 35.7 28.0 23.2 12.5 38.6 23.6 19.3 25.5 20.7 21.9 18.7 42.4 17.9 36.6 34.5 21.6 31.2 29.9 29.9 17.8 27.8 40.1 27.4 28.5 32.7 41.6 14.2 37.8 26.0 63.8 40.3 38.7 20.7 27.7 27.5 37.2 53.4 32.9 28.7 40.8 30.9 40.5 33.3 31.4 28.2 30.6 49.0 44.7 43.9 26.2 29.5 39.9 54.7 54.9 39.5 71.5 41.0 44.5 41.8 48.6 33.5 16.3 27.6 37.6 31.5 51.3 41.4 18.5 50.7 32.2 32.1 31.6 30.0 30.3 30.0 25.2 54.2 39.8 31.4 33.6 38.7 6.1 14.1 10.0 14.5 18.3 12.2 11.7 12.7 13.6 16.8 12.3 12.4 13.5 3.5 12.2 17.6 12.2 15.7 12.6 35.5 40.3 37.7 37.8 33.8 35.9 40.3 41.2 38.0 35.7 38.6 42.4 49.9 16.0 24.5 13.7 36.8 22.7 32.9 60.0 16.5 19.2 37.1 32.9 22.4 25.8 26.1 27.6 14.6 84.1 37.1 57.3 70.5 69.2 2.5 21.5 31.6 47.4 22.2 53.0 12.6 112.2 85.1 32.1 35.7 19.8 37.4 34.6 38.9 23.1 81.6 10.1 13.3 53.3 28.5 42.6 27.7 4.2 31.1 31.6 53.4 4.7 70.5 32.2 59.8 15.1 38.7 89.5 49.3 31.2 29.4 38.4 90.4 51.4 17.4 14.4 19.7 26.3 32.6 24.1 27.1 29.4 23.9 71.7 37.4 48.1 66.7 31.7 USF2 "bHLHb12, FIP" ENSG00000105698 "Upstream transcription factor 2, c-fos interacting" Q15853 19 35268962-35279821 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029764, HPA046567" Supported Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm Vesicles "HPA029764: AB_2673190, HPA046567: AB_2679702" "unprognostic (6.10e-3)" "unprognostic (2.27e-1)" "unprognostic (1.06e-2)" "unprognostic (5.03e-3)" "unprognostic (4.60e-2)" "unprognostic (1.72e-1)" "unprognostic (2.45e-1)" "unprognostic (2.87e-1)" "unprognostic (2.10e-1)" "unprognostic (7.07e-2)" "prognostic favorable (5.12e-5)" "unprognostic (7.75e-2)" "unprognostic (8.12e-2)" "unprognostic (7.47e-2)" "unprognostic (5.75e-2)" "unprognostic (6.90e-2)" "prognostic favorable (3.28e-4)" 126.7 132.5 188.9 130.4 191.7 177.7 105.4 190.2 192.9 109.3 147.9 120.8 105.3 104.4 51.5 104.6 104.1 66.3 196.6 181.0 180.3 97.8 185.2 102.2 154.9 192.9 185.4 164.5 121.1 109.4 149.1 63.5 187.2 99.8 54.1 90.4 97.9 57.2 359.3 122.0 112.7 52.4 186.4 160.5 104.1 51.7 191.7 101.3 125.8 195.1 96.7 100.2 99.9 183.2 189.2 190.2 93.6 91.1 161.7 81.5 89.2 101.0 119.7 90.4 69.3 87.3 95.5 183.7 157.6 86.3 96.4 56.5 88.6 79.6 45.4 306.4 135.8 107.5 111.1 143.1 97.8 182.5 177.5 71.7 108.3 58.6 89.1 151.3 62.2 119.6 135.3 260.0 70.5 218.8 200.7 69.8 78.7 171.3 61.1 190.9 123.2 171.2 74.8 119.5 159.3 120.7 188.2 200.4 346.7 80.7 81.8 142.4 107.4 150.0 101.0 99.5 134.4 260.0 286.6 199.7 139.4 114.8 201.0 44.5 8.3 11.1 6.8 11.2 8.2 10.2 7.0 9.0 13.4 13.5 6.3 6.0 7.8 11.7 6.9 50.6 13.8 7.7 188.9 191.7 190.2 192.9 181.0 180.3 192.9 185.4 187.2 186.4 191.7 183.2 58.2 6.4 22.4 29.7 72.5 23.7 23.7 18.7 20.5 66.0 42.2 38.4 71.6 35.8 15.5 31.3 33.3 24.2 108.1 50.7 56.7 33.5 1.1 25.6 31.3 36.5 52.1 37.2 19.7 57.8 38.5 32.7 30.5 34.0 20.3 45.7 38.6 50.5 107.0 94.2 16.9 33.6 20.3 66.8 42.9 3.4 32.0 91.9 26.6 28.1 37.8 118.9 35.0 12.1 19.5 36.0 37.1 31.2 63.8 23.1 58.1 51.7 11.0 53.9 13.1 40.9 35.8 9.0 10.6 34.3 24.7 17.5 56.2 52.0 33.0 35.6 USP18 ENSG00000184979 "Ubiquitin specific peptidase 18" Q9UMW8 22 18150170-18177397 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal tubular cells: 46.9;Extravillous trophoblasts: 31.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 181.8;BJ hTERT+ SV40 Large T+ RasG12V: 196.2" HPA044768 Uncertain Supported Vesicles,Cytosol NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol Vesicles "HPA044768: AB_10963697" "unprognostic (2.06e-1)" "unprognostic (3.55e-2)" "unprognostic (1.57e-2)" "unprognostic (5.04e-3)" "unprognostic (1.40e-2)" "unprognostic (5.42e-2)" "unprognostic (3.29e-2)" "unprognostic (5.11e-3)" "unprognostic (1.81e-1)" "unprognostic (1.79e-3)" "unprognostic (9.77e-2)" "unprognostic (1.47e-1)" "unprognostic (4.29e-3)" "unprognostic (2.58e-1)" "unprognostic (2.77e-2)" "unprognostic (2.28e-2)" "unprognostic (8.38e-2)" 10.8 5.0 3.6 5.1 3.8 8.1 8.3 3.3 4.5 4.0 4.0 5.0 6.0 3.2 7.8 4.0 7.3 6.6 4.4 3.7 3.9 5.9 23.6 7.9 9.2 5.1 3.9 2.9 4.2 3.6 5.7 5.7 4.2 5.3 4.4 0.7 14.0 2.5 3.8 3.4 6.7 4.0 7.0 11.0 7.2 9.7 4.1 15.0 7.3 5.5 6.5 4.0 3.6 3.7 14.4 14.6 4.2 18.2 18.2 13.5 18.4 7.3 17.5 181.8 196.2 2.2 20.1 0.2 10.8 4.0 57.5 4.9 21.6 6.4 6.2 64.4 29.4 28.3 1.9 27.0 2.1 6.9 25.7 6.0 2.5 12.8 0.0 1.0 40.8 20.6 1.4 1.7 1.8 24.9 33.4 16.7 12.7 15.6 11.0 13.1 28.4 0.0 3.6 12.4 15.2 11.9 8.8 15.0 71.9 16.3 9.9 6.6 66.7 1.3 3.5 4.1 7.5 3.4 45.4 0.2 16.3 17.1 10.5 3.2 3.9 8.3 8.5 11.0 10.7 5.3 7.2 11.1 1.8 3.4 8.2 9.6 0.7 13.3 8.6 3.3 13.1 5.3 3.6 3.8 3.3 4.5 3.7 3.9 5.1 3.9 4.2 7.0 4.1 3.7 9.7 9.6 4.8 0.7 2.5 1.7 4.5 5.7 2.2 0.2 8.4 8.3 1.4 8.6 6.9 0.0 0.0 4.6 3.0 6.2 46.9 5.9 1.6 20.1 2.5 8.4 3.0 1.3 0.5 11.1 31.9 7.1 4.1 6.3 0.0 8.5 11.0 5.5 8.7 0.0 0.6 3.5 6.1 6.3 0.8 1.7 3.7 3.8 3.6 0.0 1.6 5.1 8.2 2.0 0.3 13.4 3.2 7.2 2.3 2.5 5.4 8.0 12.2 0.3 6.6 8.0 2.5 10.9 1.0 4.0 1.0 1.5 5.0 5.5 2.8 2.9 USP27X USP27 ENSG00000273820 "Ubiquitin specific peptidase 27 X-linked" A6NNY8 X 49879484-49882558 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Alveolar cells type 2: 15.5;Bipolar cells: 15.8;Cytotrophoblasts: 44.5;Syncytiotrophoblasts: 26.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SuSa: 12.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077264 Approved Nucleoplasm,Vesicles NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 12: NES - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles Nucleoplasm "HPA077264: AB_2686831" "unprognostic (4.12e-2)" "unprognostic (9.58e-3)" "unprognostic (2.29e-1)" "unprognostic (4.66e-2)" "unprognostic (1.98e-1)" "unprognostic (1.74e-1)" "prognostic unfavorable (6.14e-4)" "unprognostic (3.10e-3)" "unprognostic (3.91e-2)" "unprognostic (1.31e-2)" "prognostic favorable (9.31e-4)" "unprognostic (5.37e-2)" "unprognostic (7.45e-3)" "unprognostic (1.19e-1)" "unprognostic (1.12e-1)" "unprognostic (2.01e-2)" "unprognostic (2.58e-1)" 1.6 2.5 6.0 1.3 6.2 0.5 2.0 8.0 5.8 3.0 3.1 3.2 1.0 3.9 2.9 1.6 3.5 1.6 1.8 5.3 14.4 2.7 1.8 2.7 1.7 4.9 8.4 6.3 2.6 3.0 7.3 11.7 5.9 3.0 1.4 3.8 1.6 2.8 4.4 2.1 2.1 2.8 3.6 1.8 2.4 1.3 10.5 2.6 2.4 2.1 1.7 3.0 2.2 4.4 1.6 3.8 4.2 4.8 3.8 3.1 3.6 1.6 2.6 1.8 1.4 6.9 1.6 0.9 1.6 4.2 6.0 2.6 6.0 4.0 2.6 2.0 3.1 1.6 1.1 6.2 2.6 0.5 3.4 4.4 2.7 2.6 2.6 4.4 2.5 4.2 3.4 1.5 2.9 3.7 2.5 1.2 4.8 2.7 2.7 2.7 3.7 0.3 2.9 1.4 1.1 3.2 3.4 3.0 4.0 12.9 3.5 1.1 1.9 2.1 4.3 3.8 0.7 1.6 0.4 0.6 2.5 1.4 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.0 6.2 8.0 5.8 5.3 14.4 4.9 8.4 5.9 3.6 10.5 4.4 3.5 19.2 15.5 0.7 2.5 2.9 4.5 0.3 2.2 15.8 1.9 2.7 2.6 0.0 7.5 0.0 0.0 44.5 1.4 1.7 5.9 1.5 0.1 2.1 4.1 5.2 4.2 0.0 2.9 0.7 3.6 2.7 1.1 2.1 2.5 4.0 2.5 1.9 4.0 5.0 3.3 1.3 0.0 0.6 1.0 0.3 2.1 1.2 0.0 0.0 1.5 8.3 0.0 3.5 0.8 1.2 0.5 3.4 0.5 3.3 0.5 2.9 13.2 2.5 6.6 2.5 2.6 0.2 1.3 0.9 2.3 26.1 2.0 8.8 1.6 1.7 USP40 FLJ10785 ENSG00000085982 "Ubiquitin specific peptidase 40" Q9NVE5 2 233475520-233566782 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 79.3;Oligodendrocytes: 127.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005821 Uncertain Approved "Vesicles,Focal adhesion sites" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "Focal adhesion sites" "HPA005821: AB_1080526" "unprognostic (2.19e-1)" "unprognostic (1.04e-1)" "unprognostic (1.13e-1)" "unprognostic (1.33e-1)" "unprognostic (3.70e-1)" "unprognostic (2.15e-1)" "unprognostic (5.30e-2)" "unprognostic (2.25e-1)" "unprognostic (1.80e-2)" "unprognostic (1.18e-1)" "unprognostic (1.96e-1)" "unprognostic (1.26e-1)" "unprognostic (2.22e-1)" "unprognostic (1.45e-1)" "unprognostic (4.09e-2)" "unprognostic (1.90e-2)" "unprognostic (2.53e-2)" 11.8 12.0 10.4 7.5 17.0 3.4 13.9 12.8 11.4 10.0 16.5 9.4 10.5 10.6 24.0 10.4 11.5 11.6 8.2 10.2 12.0 14.2 13.2 12.5 7.2 19.4 14.2 15.9 14.0 16.8 8.5 12.4 19.0 13.5 9.5 14.2 12.9 10.4 9.6 19.7 10.1 8.5 12.3 9.9 13.1 14.7 16.2 10.1 16.4 7.6 7.8 9.6 7.5 25.4 17.3 19.9 17.6 12.0 25.2 23.0 15.7 16.4 12.4 14.7 16.0 14.3 20.2 0.4 4.7 26.4 38.6 30.3 13.3 29.7 20.6 0.0 9.0 13.3 17.4 24.3 22.3 5.8 8.9 22.2 21.1 22.2 30.9 26.2 17.3 8.1 22.0 3.2 21.4 14.0 6.2 8.5 7.9 17.8 16.0 0.0 36.3 8.1 17.9 27.6 9.6 10.3 13.5 13.5 16.9 12.9 15.4 12.9 17.3 20.9 13.1 8.9 20.6 6.0 4.9 0.8 27.1 10.2 18.6 0.0 1.0 0.0 0.5 1.1 0.2 0.4 0.5 0.4 1.5 0.7 0.7 0.7 0.1 0.5 0.9 1.9 0.8 0.5 10.4 17.0 12.8 11.4 10.2 12.0 19.4 14.2 19.0 12.3 16.2 25.4 11.8 32.1 35.5 79.3 7.9 7.4 9.1 13.6 15.4 18.1 17.0 14.7 10.7 10.0 19.9 16.5 25.0 21.2 6.7 9.9 7.9 9.4 8.4 19.8 18.3 11.1 15.0 5.7 25.9 12.6 10.6 11.9 21.4 21.3 9.5 23.4 12.8 25.4 8.2 23.5 38.2 10.9 4.1 11.6 3.6 10.7 6.8 9.1 3.6 40.3 5.9 11.9 4.1 48.2 127.7 10.5 12.6 8.2 10.9 12.9 13.9 14.6 21.0 19.4 13.1 17.5 10.6 30.2 20.9 17.2 10.5 15.7 5.5 21.1 12.1 10.0 USP47 ENSG00000170242 "Ubiquitin specific peptidase 47" Q96K76 11 11841423-11961887 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 315.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029286, HPA029289" Supported Approved "Vesicles,Intermediate filaments" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" "Intermediate filaments" Vesicles "HPA029286: AB_10599852, HPA029289: AB_10601675" "unprognostic (2.02e-1)" "unprognostic (2.72e-1)" "unprognostic (3.05e-1)" "unprognostic (1.84e-1)" "unprognostic (2.99e-2)" "unprognostic (2.65e-2)" "unprognostic (2.27e-2)" "unprognostic (7.39e-2)" "unprognostic (1.54e-2)" "unprognostic (7.05e-2)" "unprognostic (2.83e-2)" "unprognostic (2.35e-1)" "unprognostic (1.51e-1)" "unprognostic (9.96e-3)" "unprognostic (1.90e-1)" "unprognostic (1.49e-1)" "unprognostic (2.85e-1)" 15.7 14.3 11.9 11.4 15.8 19.0 15.1 17.3 12.8 14.3 10.2 19.8 10.3 17.2 15.6 16.1 13.5 12.3 23.5 12.5 14.1 13.2 23.3 16.2 13.3 14.1 12.8 15.9 16.9 22.2 13.8 16.7 15.0 16.6 12.3 25.7 14.1 15.4 59.8 18.0 14.1 17.8 14.1 11.8 16.6 15.0 12.7 19.1 14.9 33.6 13.8 16.7 14.2 20.6 26.8 15.7 30.3 13.1 21.8 23.2 12.6 31.6 22.3 20.1 22.1 16.5 22.2 29.6 13.3 28.0 23.7 17.8 23.7 15.3 30.3 27.5 20.4 18.6 30.3 12.6 21.5 25.0 23.9 22.3 22.5 12.3 29.0 26.1 21.8 21.7 35.8 23.7 25.4 10.6 21.7 14.3 7.9 28.1 12.7 21.4 30.3 9.4 24.6 29.1 9.8 21.0 25.8 19.6 19.3 18.4 14.4 20.6 24.9 27.8 16.2 22.3 19.6 7.9 18.1 25.9 19.9 15.2 20.3 14.7 5.9 11.9 11.0 7.4 14.5 7.4 10.3 11.4 7.9 6.7 13.1 11.4 2.8 18.5 11.5 4.8 8.3 7.9 11.9 15.8 17.3 12.8 12.5 14.1 14.1 12.8 15.0 14.1 12.7 20.6 41.1 70.5 63.1 116.5 46.9 71.0 68.8 28.8 45.5 67.5 41.1 30.9 222.5 40.0 56.0 23.9 47.9 69.6 57.2 30.4 25.4 39.5 40.1 49.8 63.0 44.8 59.3 34.3 122.7 38.9 33.2 69.7 44.4 134.5 54.3 52.6 32.5 53.9 28.0 63.9 136.5 32.9 24.4 27.7 39.7 30.0 44.1 41.8 24.9 96.5 40.5 79.7 68.0 171.4 315.9 44.8 31.5 50.0 55.2 65.5 29.7 21.9 48.2 52.4 52.6 85.0 68.2 92.8 55.1 46.6 87.9 125.7 65.0 41.8 35.0 58.9 USP6 "HRP1, Tre-2, TRE17, Tre2, TRESMCR" ENSG00000129204 "Ubiquitin specific peptidase 6" P35125 17 5116032-5175034 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Calmodulin-binding, Hydrolase, Protease, Thiol protease" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "skeletal muscle: 19.6;testis: 13.4" "Cell type enhanced" "Detected in many" "Early spermatids: 24.4;Spermatocytes: 26.9" "Cancer enriched" "Detected in single" 14 "testis cancer: 2.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046969 Uncertain Vesicles NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 37: Myocytes - Muscle contraction" Vesicles "HPA046969: " "unprognostic (3.89e-2)" "unprognostic (3.79e-3)" "unprognostic (2.50e-1)" "unprognostic (1.85e-1)" "unprognostic (9.32e-2)" "unprognostic (3.50e-3)" "unprognostic (1.29e-1)" "unprognostic (1.67e-2)" "unprognostic (3.45e-2)" "unprognostic (2.46e-2)" "unprognostic (7.91e-4)" "unprognostic (6.28e-3)" "unprognostic (3.24e-4)" "unprognostic (3.75e-2)" "unprognostic (3.13e-1)" "unprognostic (2.71e-1)" "unprognostic (7.09e-4)" 0.4 0.3 0.2 0.2 0.5 0.1 0.7 0.3 0.6 1.4 1.5 0.8 0.0 0.9 0.7 0.2 0.5 0.5 0.4 0.4 0.3 0.6 0.1 0.4 0.3 0.7 0.2 2.6 0.3 0.0 0.6 0.5 0.6 0.6 0.3 2.5 0.5 0.4 19.6 0.6 0.3 0.9 0.2 0.4 0.2 13.4 0.5 0.0 0.9 0.6 0.2 0.3 0.5 0.9 0.1 0.1 0.3 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.2 0.2 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.2 0.1 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.1 0.0 0.2 0.4 0.3 0.1 0.1 0.0 0.3 0.2 0.0 0.3 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.5 0.3 0.6 0.4 0.3 0.7 0.2 0.6 0.2 0.5 0.9 2.0 6.4 10.8 0.0 0.4 10.8 1.0 1.1 0.0 8.5 4.0 3.8 1.6 5.7 3.5 3.7 12.5 0.6 1.0 0.1 3.9 0.0 24.4 1.1 2.1 3.0 0.0 5.3 1.2 0.0 0.8 1.8 0.0 1.4 0.0 1.2 3.6 3.2 2.7 1.7 1.0 0.0 0.0 5.4 6.4 13.5 1.8 3.1 3.6 2.8 3.2 5.1 0.0 0.0 2.9 0.1 0.1 2.6 0.1 2.1 0.0 3.2 4.0 12.3 6.6 5.9 1.7 26.9 11.5 0.0 10.4 0.7 1.1 0.9 0.2 1.1 USP9X "DFFRX, FAF, MRX99" ENSG00000124486 "Ubiquitin specific peptidase 9 X-linked" Q93008 X 41085445-41236579 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Cell division, Chromosome partition, Mitosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011618, HPA047417, CAB070164" Approved Uncertain Vesicles NA NA 24000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Vesicles "CAB011618: AB_470860, CAB070164: AB_10011071, HPA047417: " "unprognostic (5.42e-3)" "unprognostic (6.42e-2)" "unprognostic (3.19e-3)" "unprognostic (2.94e-2)" "unprognostic (5.99e-2)" "unprognostic (4.76e-1)" "unprognostic (1.82e-2)" "unprognostic (4.07e-1)" "unprognostic (1.90e-1)" "unprognostic (1.72e-1)" "unprognostic (7.07e-2)" "unprognostic (1.09e-1)" "unprognostic (5.82e-2)" "unprognostic (1.59e-1)" "unprognostic (4.19e-2)" "unprognostic (2.78e-1)" "unprognostic (1.33e-1)" 16.4 16.8 11.9 14.3 13.9 18.2 14.2 12.7 12.8 15.3 14.3 14.8 13.6 15.4 14.9 14.1 16.0 13.0 15.3 14.3 13.2 17.8 33.9 14.4 15.8 12.2 13.1 13.4 16.0 30.0 10.2 18.4 13.8 12.3 13.7 22.0 11.5 15.3 39.1 13.8 14.3 16.3 12.5 13.3 13.8 17.5 12.8 18.8 19.5 28.4 16.2 15.0 12.6 16.4 38.6 44.2 39.1 40.2 33.0 32.7 8.8 21.5 28.8 23.8 27.5 21.1 16.9 25.7 11.5 48.5 71.3 25.3 67.1 39.7 39.7 32.0 50.5 29.3 41.3 19.9 27.6 26.4 21.0 29.3 17.9 56.4 53.4 35.5 37.2 17.1 36.0 20.3 38.6 29.1 18.8 12.7 42.6 14.1 24.7 20.3 51.8 16.9 24.7 30.7 22.2 20.8 89.0 26.7 26.0 69.8 24.3 16.2 40.2 36.6 27.6 34.6 24.0 19.1 22.3 30.9 26.4 12.1 18.5 1.7 2.3 3.0 2.5 1.9 3.6 2.8 3.0 2.7 2.6 2.1 3.0 2.8 6.4 2.5 2.5 2.1 2.8 1.5 11.9 13.9 12.7 12.8 14.3 13.2 12.2 13.1 13.8 12.5 12.8 16.4 38.1 41.7 35.1 48.0 42.6 48.3 30.8 29.6 55.2 38.1 41.3 29.5 83.5 54.3 37.9 27.6 37.5 39.6 46.3 58.5 7.9 28.4 14.9 85.5 56.9 43.6 26.9 41.0 84.9 26.5 25.4 41.4 41.8 136.9 25.9 58.3 45.7 62.8 32.6 37.0 86.0 39.1 18.3 47.8 42.1 15.4 33.2 55.5 33.8 67.5 44.6 31.3 30.9 74.9 108.0 32.6 40.1 49.2 38.8 35.6 47.7 21.5 35.8 31.2 32.9 70.6 48.3 86.4 82.9 55.2 55.3 46.7 42.4 45.8 38.0 40.2 USP9Y "AZFA, DFFRY" ENSG00000114374 "Ubiquitin specific peptidase 9 Y-linked" O00507 Y 12537650-12860839 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Excitatory neurons: 89.5;Inhibitory neurons: 69.5" "Cancer enhanced" "Detected in many" "prostate cancer: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 21.5;RT4: 17.4" "Not detected" "Not detected" HPA057687 Uncertain Vesicles NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 54: Non-specific - Microtubule organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Vesicles "HPA057687: " "unprognostic (2.63e-1)" "unprognostic (8.97e-2)" "unprognostic (1.10e-5)" "unprognostic (8.46e-3)" "unprognostic (4.93e-2)" "unprognostic (2.53e-2)" "unprognostic (2.77e-1)" "unprognostic (3.17e-2)" "unprognostic (1.71e-1)" "unprognostic (4.05e-2)" "unprognostic (1.41e-4)" "unprognostic (2.28e-1)" "unprognostic (1.19e-2)" "unprognostic (1.42e-1)" 3.6 5.2 1.3 1.7 1.4 2.6 3.3 2.8 5.2 0.0 2.5 4.5 1.7 0.0 7.2 5.2 0.0 4.6 5.5 1.3 1.4 7.1 3.0 5.2 2.2 1.2 1.1 0.0 6.0 3.5 8.8 2.3 1.3 9.7 4.9 12.9 4.9 7.0 5.2 3.2 4.4 0.0 1.0 5.1 3.9 4.2 1.4 0.0 5.7 9.7 5.6 4.5 0.0 2.4 0.0 4.7 0.0 0.0 0.0 0.0 5.3 14.2 14.6 7.2 8.5 0.0 0.0 7.7 0.0 12.2 0.0 0.0 0.0 0.0 8.6 8.1 0.0 7.3 0.0 9.5 5.8 0.0 0.0 9.7 8.9 0.0 0.0 0.0 0.0 3.0 0.0 0.0 12.2 0.0 9.8 0.0 4.6 0.0 0.0 0.0 3.5 2.1 21.5 17.4 7.2 0.0 0.0 0.0 4.4 12.5 0.0 0.2 10.6 9.5 0.0 0.0 7.0 0.0 9.7 15.1 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.9 0.4 0.7 0.5 0.1 0.7 0.8 0.5 0.0 0.1 0.0 0.6 0.6 0.0 1.3 1.4 2.8 5.2 1.3 1.4 1.2 1.1 1.3 1.0 1.4 2.4 0.0 25.6 23.5 29.4 11.0 11.7 8.5 9.5 18.2 23.6 0.0 0.0 26.5 7.2 12.6 20.2 64.6 6.3 5.3 0.3 1.9 6.9 0.5 0.0 0.0 5.8 0.0 5.9 89.5 0.0 1.7 8.1 6.6 0.0 2.5 0.0 6.1 2.3 3.1 26.9 69.5 1.1 8.2 5.6 9.3 1.1 12.5 3.6 3.6 31.9 3.6 8.8 14.4 28.6 17.4 2.3 0.0 15.4 4.1 13.2 0.7 6.3 19.9 23.1 0.0 5.2 4.4 2.8 2.6 20.6 11.6 3.4 14.7 0.0 1.5 11.9 UTP3 "CRLZ1, DKFZp761F222, FLJ23256, SAS10" ENSG00000132467 "UTP3 small subunit processome component" Q9NQZ2 4 70688532-70690551 "Predicted intracellular proteins" "Chromatin regulator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035655, HPA041453" Approved Supported Nucleoli,Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" Nucleoli Vesicles "HPA035655: AB_10601832, HPA041453: AB_2677488" "unprognostic (2.44e-2)" "unprognostic (9.70e-2)" "unprognostic (7.36e-3)" "unprognostic (2.72e-2)" "unprognostic (1.15e-1)" "unprognostic (1.90e-2)" "unprognostic (6.79e-3)" "unprognostic (2.13e-1)" "unprognostic (3.50e-2)" "unprognostic (1.66e-1)" "unprognostic (1.53e-1)" "unprognostic (4.44e-3)" "prognostic favorable (3.16e-4)" "unprognostic (4.45e-2)" "unprognostic (7.95e-2)" "unprognostic (2.24e-1)" "unprognostic (2.24e-2)" 22.4 22.7 8.9 25.5 9.5 19.1 18.7 9.4 11.3 14.0 10.0 16.9 16.3 16.1 15.0 20.6 16.3 14.6 17.0 9.9 9.8 21.0 27.1 18.6 33.0 9.1 9.3 15.7 14.9 16.3 9.4 16.3 9.1 15.1 16.4 12.0 15.9 13.7 15.9 18.8 21.5 20.2 8.7 34.5 17.8 11.4 9.6 32.1 16.0 13.1 31.5 22.1 12.3 10.0 33.7 32.3 42.4 35.4 58.9 44.3 36.3 68.4 43.9 38.4 37.0 42.4 43.7 147.4 42.1 58.9 43.8 27.7 62.7 93.7 55.4 45.9 35.9 56.1 43.0 45.9 63.9 85.9 47.9 60.4 55.2 47.0 46.0 42.3 52.2 42.3 65.3 48.2 62.8 69.7 79.9 47.8 29.6 68.9 46.7 33.8 58.3 60.5 69.7 53.7 35.5 48.4 29.1 65.4 44.5 46.1 36.1 34.2 58.5 38.8 65.9 37.3 44.3 69.6 55.4 104.8 47.3 41.4 34.8 8.4 10.7 5.6 6.4 12.6 6.8 7.0 5.3 7.4 13.4 6.1 7.7 6.7 0.8 6.8 11.3 13.5 7.3 5.5 8.9 9.5 9.4 11.3 9.9 9.8 9.1 9.3 9.1 8.7 9.6 10.0 19.2 57.7 54.2 4.9 23.7 22.9 44.3 42.2 24.5 19.4 12.3 14.4 20.6 14.3 50.5 12.9 6.2 26.7 30.0 11.8 19.6 29.3 1.1 22.8 29.3 26.7 15.0 16.8 6.2 29.8 14.6 23.6 21.9 25.1 29.2 16.7 16.8 25.1 21.9 16.8 5.9 14.7 30.5 37.8 24.2 2.2 17.4 24.2 12.4 5.6 27.9 26.8 30.9 2.5 8.9 22.6 9.5 25.2 18.5 23.0 15.9 27.9 45.7 22.3 13.1 30.8 48.8 11.5 9.5 23.0 25.6 21.6 24.6 22.2 15.6 29.9 VAC14 "ArPIKfyve, FLJ10305, TAX1BP2" ENSG00000103043 "VAC14 component of PIKFYVE complex" Q08AM6 16 70687439-70801160 "Disease related genes, Predicted intracellular proteins" "Host-virus interaction" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 74.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027766, HPA075382" Approved Supported Vesicles,Cytosol NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" Vesicles Cytosol "HPA027766: AB_1848651, HPA075382: " "unprognostic (9.25e-2)" "prognostic favorable (8.33e-5)" "unprognostic (2.83e-2)" "unprognostic (1.51e-1)" "unprognostic (8.94e-2)" "unprognostic (2.72e-1)" "unprognostic (2.21e-2)" "unprognostic (8.93e-3)" "unprognostic (1.03e-1)" "unprognostic (1.34e-2)" "unprognostic (7.20e-2)" "unprognostic (3.26e-1)" "prognostic favorable (1.56e-6)" "unprognostic (1.61e-1)" "unprognostic (1.10e-1)" "unprognostic (5.05e-2)" "unprognostic (1.80e-1)" 17.3 25.0 20.6 14.5 19.3 11.3 17.1 19.5 24.7 16.2 18.0 16.7 12.1 16.9 8.6 19.0 15.1 10.2 20.3 20.8 20.5 26.3 27.1 16.9 24.7 21.5 20.0 14.3 23.7 17.5 16.6 10.9 21.4 17.5 8.3 6.8 17.4 10.7 24.3 23.0 17.9 11.5 19.2 22.5 20.7 16.2 21.6 15.5 21.4 12.0 13.9 18.1 14.9 21.6 25.9 25.3 21.0 23.6 29.9 20.3 32.0 18.5 29.0 34.6 15.5 31.6 41.0 33.3 23.3 22.5 39.9 32.3 27.8 30.1 16.3 10.0 28.2 16.9 18.6 39.5 76.8 29.1 33.7 36.0 30.9 50.7 45.1 20.7 33.0 29.2 30.1 14.6 30.1 37.3 27.1 48.5 36.9 20.4 22.7 32.3 14.9 48.6 16.7 17.4 24.9 26.7 60.9 18.5 43.0 15.2 27.4 27.0 26.7 45.7 25.9 29.2 20.4 20.4 27.5 62.9 76.1 25.1 21.3 0.8 2.7 4.4 1.5 3.6 1.4 2.5 2.2 3.1 5.6 3.9 2.0 1.8 1.0 2.4 3.6 3.1 1.3 1.1 20.6 19.3 19.5 24.7 20.8 20.5 21.5 20.0 21.4 19.2 21.6 21.6 5.1 3.2 4.2 15.0 10.1 4.2 7.8 7.0 9.6 8.4 8.4 7.4 12.6 12.8 8.0 3.7 2.1 16.7 4.0 11.5 5.9 19.2 20.4 14.2 5.4 8.2 9.1 5.7 11.7 22.5 29.2 5.9 11.7 6.7 5.7 11.6 16.4 15.9 42.9 10.1 13.8 10.0 14.2 18.3 13.5 74.4 6.2 15.6 10.6 10.3 19.2 6.8 8.2 8.5 16.3 20.8 10.8 3.4 15.8 8.9 13.7 15.0 14.6 7.7 6.6 5.9 7.9 4.8 13.5 10.3 9.1 19.6 6.5 8.7 12.6 7.1 VAMP7 "SYBL1, TI-VAMP, VAMP-7" ENSG00000124333 "Vesicle associated membrane protein 7" P51809 X 155881345-155943769 "Predicted intracellular proteins, Predicted membrane proteins" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036733 Approved Supported Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 51: Myeloid cells - Hemostasis" Vesicles "HPA036733: AB_10672228" "unprognostic (7.54e-3)" "unprognostic (1.35e-2)" "unprognostic (2.07e-1)" "unprognostic (1.04e-1)" "unprognostic (6.15e-3)" "unprognostic (2.70e-2)" "unprognostic (5.77e-2)" "unprognostic (7.95e-2)" "unprognostic (7.18e-2)" "unprognostic (3.38e-3)" "unprognostic (1.02e-1)" "unprognostic (1.15e-1)" "prognostic favorable (2.83e-4)" "unprognostic (1.29e-1)" "unprognostic (3.42e-1)" "unprognostic (2.47e-1)" "unprognostic (2.97e-1)" 29.4 24.3 17.8 24.1 20.6 37.1 23.8 22.3 24.9 23.2 18.3 22.9 23.4 21.4 15.5 22.6 16.5 22.2 19.6 18.1 21.4 39.2 47.9 24.8 26.4 20.7 20.5 17.9 14.3 32.3 8.7 40.5 21.5 21.4 24.4 10.3 17.3 20.1 21.9 20.1 27.5 28.2 20.4 21.8 18.4 14.9 19.9 29.9 24.4 24.1 28.6 25.6 15.9 23.0 72.9 31.3 21.0 43.6 57.0 54.3 56.3 55.3 49.1 49.0 98.4 33.8 46.5 100.6 100.0 66.9 55.5 25.5 47.6 38.9 64.5 42.3 41.6 41.8 43.1 24.3 63.6 86.9 62.8 50.9 37.9 54.8 49.8 42.8 55.4 43.5 91.1 54.2 56.0 36.5 34.1 48.8 15.0 54.1 45.3 25.5 41.2 75.3 65.6 36.2 16.0 46.0 32.7 32.6 49.6 54.8 31.9 71.8 58.4 44.8 46.7 65.0 79.6 123.8 167.8 138.9 39.2 104.4 51.0 86.8 25.3 39.6 15.1 27.0 19.1 12.3 17.7 18.6 26.4 13.2 16.2 17.5 21.9 22.7 26.7 15.0 22.0 22.4 17.8 20.6 22.3 24.9 18.1 21.4 20.7 20.5 21.5 20.4 19.9 23.0 17.8 3.2 9.2 11.1 21.2 19.6 14.7 11.8 20.5 7.6 16.6 9.5 12.3 5.7 12.5 7.3 6.2 48.4 24.9 14.1 41.1 28.0 6.9 13.8 14.5 19.8 13.2 31.4 14.2 26.0 49.7 19.6 12.2 13.7 31.1 22.5 20.3 25.1 31.1 6.7 14.6 12.8 10.2 30.8 49.0 6.9 17.7 35.9 19.6 7.5 32.5 10.4 29.9 8.0 19.2 29.9 13.5 19.5 15.2 17.5 25.3 52.9 10.5 4.6 26.3 10.8 18.9 45.4 26.3 20.3 19.5 69.8 21.6 25.3 15.3 20.1 VAV2 ENSG00000160293 "Vav guanine nucleotide exchange factor 2" P52735 9 133761894-133992604 "Plasma proteins, Predicted intracellular proteins" Angiogenesis "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 48.3;Inhibitory neurons: 40.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 3.3" "Group enriched" "Detected in many" 22 "B-cells: 3.3;dendritic cells: 1.1;monocytes: 2.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003224 Uncertain Approved Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA003224: AB_1080554" "unprognostic (1.56e-1)" "unprognostic (1.10e-1)" "unprognostic (1.07e-2)" "unprognostic (1.09e-1)" "unprognostic (3.43e-1)" "unprognostic (1.19e-1)" "unprognostic (6.57e-2)" "unprognostic (1.16e-3)" "unprognostic (1.83e-2)" "unprognostic (3.74e-3)" "unprognostic (4.73e-2)" "unprognostic (9.16e-2)" "prognostic favorable (7.39e-7)" "unprognostic (8.64e-3)" "unprognostic (3.00e-2)" "prognostic unfavorable (4.33e-4)" "unprognostic (3.97e-2)" 8.4 26.8 9.3 10.7 8.8 3.0 7.7 7.4 9.8 12.0 10.9 11.8 20.9 9.9 7.2 6.7 12.2 10.8 7.4 11.6 9.9 21.3 46.1 16.8 13.3 11.6 16.0 5.5 38.6 10.8 8.0 13.1 13.2 10.2 9.6 3.0 13.2 8.9 2.0 6.1 22.4 6.9 8.9 13.9 9.5 4.4 9.9 6.2 13.8 2.3 13.3 11.4 7.9 8.4 12.5 21.6 33.3 13.5 9.0 15.1 85.8 24.6 13.5 20.3 12.2 33.0 19.0 3.6 19.6 24.6 26.2 72.8 31.6 53.0 10.4 21.3 7.3 4.2 28.3 37.2 33.4 10.3 1.6 15.0 33.5 17.9 25.3 13.6 22.9 7.3 7.3 6.0 14.2 63.5 0.8 5.1 16.3 54.3 20.5 33.9 28.2 12.1 46.1 22.4 36.9 24.9 64.7 42.7 8.8 21.3 26.0 14.5 18.7 28.6 16.0 28.7 34.5 0.4 0.3 6.8 19.1 8.8 18.0 0.0 0.8 0.0 0.0 2.0 0.0 3.3 0.0 0.0 1.1 2.1 0.0 0.0 0.0 0.0 1.4 0.7 0.0 0.5 9.3 8.8 7.4 9.8 11.6 9.9 11.6 16.0 13.2 8.9 9.9 8.4 4.8 0.0 5.4 20.5 11.2 5.1 3.0 10.1 4.0 1.9 6.7 5.6 4.7 21.5 7.5 36.8 0.0 1.3 0.6 27.0 3.9 9.2 2.5 6.9 6.4 6.6 28.2 0.4 8.5 12.5 18.3 5.0 9.7 13.9 0.0 24.6 6.8 48.3 6.2 0.0 40.9 9.8 6.1 5.4 7.2 7.9 7.2 7.7 1.8 8.4 9.3 4.2 2.1 31.2 2.6 24.7 15.6 6.0 3.3 6.3 35.7 13.6 3.3 1.8 13.1 6.4 8.8 0.1 3.8 2.1 2.7 1.0 1.7 12.0 13.5 2.1 VBP1 "PFD3, PFDN3" ENSG00000155959 "VHL binding protein 1" P61758 X 155197007-155239841 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006260, HPA023230" Approved Supported Vesicles,Cytosol NA NA 15000 "Cluster 49: Eosinophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" Cytosol Vesicles "CAB006260: AB_425740, HPA023230: AB_1858727" "unprognostic (1.55e-3)" "unprognostic (1.12e-3)" "unprognostic (3.35e-1)" "unprognostic (1.35e-2)" "unprognostic (3.78e-2)" "unprognostic (1.85e-3)" "unprognostic (5.31e-3)" "unprognostic (1.40e-1)" "unprognostic (2.44e-2)" "unprognostic (1.02e-2)" "unprognostic (9.80e-2)" "unprognostic (1.15e-1)" "unprognostic (5.76e-2)" "unprognostic (3.76e-2)" "unprognostic (4.54e-2)" "unprognostic (9.30e-2)" "unprognostic (3.80e-1)" 32.1 32.5 48.6 29.4 50.2 50.5 31.6 54.6 60.5 24.2 43.6 30.1 23.0 25.2 26.6 31.0 23.5 21.1 65.7 49.5 53.7 40.4 31.2 23.3 41.3 52.7 52.8 25.5 19.7 38.2 29.7 30.2 53.4 30.9 33.0 48.2 20.6 25.4 101.5 19.3 24.3 28.9 54.6 24.8 22.6 15.9 51.9 45.8 31.6 121.2 40.4 32.2 19.9 60.1 162.8 57.6 122.1 81.1 49.6 68.0 35.2 78.8 60.7 99.7 155.3 69.1 80.8 207.1 163.6 66.8 154.1 62.4 179.3 74.0 129.5 110.0 123.9 87.6 86.0 54.2 58.9 142.6 65.5 51.0 84.7 84.7 105.6 53.1 93.7 101.0 173.4 119.9 113.6 67.7 134.3 120.9 71.0 149.1 122.1 114.0 97.0 121.4 86.8 73.0 132.0 80.0 54.1 62.7 90.1 83.4 53.8 107.5 55.6 80.5 100.0 138.3 198.0 133.9 209.0 361.3 71.6 173.1 101.0 22.5 23.0 75.8 26.3 25.1 30.2 28.6 30.5 31.7 36.2 23.7 34.5 37.5 26.3 28.2 21.9 29.5 43.2 33.0 48.6 50.2 54.6 60.5 49.5 53.7 52.7 52.8 53.4 54.6 51.9 60.1 40.7 51.3 29.1 12.1 55.1 57.4 81.2 89.9 33.6 54.9 33.2 30.2 80.5 30.0 48.0 38.6 20.9 73.7 60.4 27.9 191.7 65.8 2.5 32.8 41.3 47.3 23.4 128.6 12.7 57.6 101.4 52.6 28.5 28.9 47.5 36.6 30.7 24.9 67.6 32.0 14.2 30.0 75.3 29.5 64.4 4.6 42.0 40.7 46.2 6.5 80.1 78.7 47.4 6.6 21.3 52.7 43.1 39.9 56.8 78.0 29.3 126.3 37.2 46.3 46.0 45.1 52.8 80.7 88.2 37.1 52.6 68.7 60.0 81.6 45.9 63.0 VCAN "CSPG2, PG-M" ENSG00000038427 Versican P13611 5 83471618-83582303 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 975.7;Granulosa cells: 1131.8;Kupffer cells: 547.3;Macrophages: 605.6;monocytes: 948.1;Oligodendrocyte precursor cells: 1644.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 240.0;myeloid DC: 88.9" "Group enriched" "Detected in many" 20 "dendritic cells: 88.9;monocytes: 240.0" "Cell line enhanced" "Detected in many" "AF22: 300.5;HSkMC: 199.5;hTERT-RPE1: 959.0;RPTEC TERT1: 381.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004726, CAB008979" Supported Approved Vesicles "Secreted to blood" NA NA 12000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "CAB008979: , HPA004726: AB_1080561" "unprognostic (7.90e-2)" "unprognostic (9.03e-3)" "unprognostic (7.09e-2)" "unprognostic (6.06e-3)" "unprognostic (1.87e-1)" "unprognostic (4.49e-2)" "unprognostic (1.23e-2)" "unprognostic (1.17e-2)" "prognostic unfavorable (7.59e-4)" "unprognostic (4.36e-3)" "unprognostic (2.68e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (5.17e-4)" "prognostic unfavorable (1.41e-4)" "unprognostic (1.15e-1)" "unprognostic (4.44e-2)" "unprognostic (5.30e-3)" 42.0 23.9 18.6 74.9 20.8 32.6 15.6 24.2 23.0 29.4 5.2 11.3 3.8 17.8 1.8 3.8 8.6 30.5 45.0 25.7 27.8 6.5 2.7 34.4 2.3 36.1 19.3 2.1 3.1 2.4 2.1 73.5 31.3 6.8 10.7 0.2 7.6 4.2 3.9 11.2 5.7 48.0 28.9 13.9 7.7 4.8 44.9 2.7 6.6 6.8 1.9 48.3 7.2 42.7 0.2 5.6 300.5 0.1 119.8 81.5 0.1 2.3 6.2 2.1 1.5 3.1 0.2 0.0 45.2 111.5 3.9 0.0 0.4 0.4 1.7 0.1 9.8 2.1 0.0 2.3 5.5 0.1 0.0 199.5 0.1 127.6 1.2 959.0 0.1 0.0 0.0 0.1 64.6 0.0 0.5 0.0 51.1 0.0 10.3 0.0 63.0 0.1 381.0 0.0 3.6 15.5 0.0 0.0 0.2 33.2 0.2 0.5 116.5 90.6 0.5 168.3 179.0 0.0 0.1 0.2 41.8 0.1 16.4 8.3 240.0 0.5 0.5 31.3 0.3 0.2 0.1 0.1 88.9 0.1 0.1 0.0 3.9 0.5 3.5 1.7 0.0 94.0 18.6 20.8 24.2 23.0 25.7 27.8 36.1 19.3 31.3 28.9 44.9 42.7 23.4 19.2 19.8 128.9 5.5 38.6 10.6 14.9 1.2 0.0 1.8 1.9 8.2 44.3 17.5 25.8 0.0 5.9 7.4 0.0 0.0 1.9 3.0 64.4 975.7 29.9 0.0 5.2 1.5 0.7 7.0 348.1 3.6 241.3 12.6 1131.8 16.8 3.6 25.6 0.0 30.7 0.2 0.0 547.3 83.1 2.5 18.6 605.6 44.4 20.6 948.1 0.0 13.4 1644.7 1.5 32.3 1.1 117.8 2.5 2.5 0.0 1.8 16.2 0.0 0.0 11.0 80.6 0.9 1.2 1.1 28.7 11.5 12.7 1.6 0.3 0.9 VGF "SCG7, SgVII" ENSG00000128564 "VGF nerve growth factor inducible" O15240 7 101162509-101165569 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 1407.4" "Group enriched" "Detected in many" 4 "Enteroendocrine cells: 128.3;Horizontal cells: 225.4" "Cancer enriched" "Detected in many" 6 "melanoma: 236.3" "Region enriched" "Detected in all" 6 "hypothalamus: 1407.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SH-SY5Y: 172.0;SK-MEL-30: 511.5;U-2 OS: 85.9;WM-115: 141.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055177, HPA072505" Enhanced Enhanced "Golgi apparatus,Vesicles" "Secreted to blood" NA NA 1270000 3100000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Golgi apparatus, Vesicles" "HPA055177: AB_2682728, HPA072505: AB_2686528" "unprognostic (3.04e-2)" "unprognostic (3.45e-1)" "unprognostic (3.19e-3)" "prognostic unfavorable (4.25e-4)" "prognostic unfavorable (3.31e-4)" "unprognostic (1.51e-2)" "unprognostic (2.86e-2)" "unprognostic (1.66e-3)" "unprognostic (2.25e-2)" "unprognostic (8.77e-2)" "unprognostic (3.84e-3)" "unprognostic (3.70e-3)" "unprognostic (9.82e-3)" "unprognostic (3.79e-1)" "unprognostic (7.23e-2)" "unprognostic (4.36e-3)" "unprognostic (2.21e-1)" 2.1 3.1 23.7 0.8 24.8 0.1 0.1 5.5 174.6 0.0 0.0 0.5 0.1 0.7 0.0 0.0 0.0 0.0 0.1 22.7 1407.4 3.6 0.0 0.1 0.0 235.4 69.9 0.1 16.1 0.0 117.0 0.0 158.8 0.1 0.0 2.2 0.0 0.0 0.0 0.8 0.3 0.2 16.6 0.1 1.9 0.9 48.7 0.0 0.6 0.0 0.0 0.0 0.1 27.3 2.2 1.1 1.1 9.5 0.0 0.0 10.3 0.9 0.0 0.0 0.0 2.4 0.9 0.1 3.1 0.0 1.4 1.4 0.5 0.1 0.0 1.0 0.7 0.3 0.0 0.9 0.1 0.6 4.4 0.1 0.2 0.2 0.7 0.0 0.0 0.1 3.7 2.3 0.0 23.4 0.1 2.4 17.6 1.0 2.3 0.8 0.0 0.1 0.3 0.1 14.1 172.0 0.3 0.9 511.5 1.1 0.4 0.3 0.0 0.4 85.9 0.0 2.0 0.1 0.8 4.7 13.5 0.4 141.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 24.8 5.5 174.6 22.7 1407.4 235.4 69.9 158.8 16.6 48.7 27.3 1.7 0.0 0.0 3.6 0.9 1.5 1.0 0.0 1.2 22.0 0.9 0.6 2.9 0.0 0.0 0.0 0.0 1.5 1.0 1.3 29.4 0.3 0.1 0.4 0.4 0.9 128.3 0.0 22.7 0.0 8.4 0.3 3.1 0.5 0.0 1.4 0.0 0.0 0.6 225.4 37.7 4.5 0.0 0.0 0.4 0.6 0.6 0.7 0.0 11.2 0.0 2.1 0.0 4.0 4.8 5.9 2.8 0.0 0.9 4.3 2.7 1.2 0.0 5.0 0.0 0.1 0.8 0.2 4.3 0.6 2.3 1.4 0.5 5.4 2.3 0.6 VLDLR "CARMQ1, CHRMQ1, VLDLRCH" ENSG00000147852 "Very low density lipoprotein receptor" P98155 9 2621182-2660056 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Endocytosis, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Receptor "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 77.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 78.1;Cone photoreceptor cells: 104.3;Oligodendrocytes: 39.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "eosinophil: 6.3" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.3" "Cell line enhanced" "Detected in many" "BEWO: 22.3;JURKAT: 20.5;THP-1: 33.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032462, HPA051312" Uncertain Uncertain "Vesicles,Cytokinetic bridge,Centriolar satellite" Yes NA 330000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "Cytokinetic bridge, Centriolar satellite" "CAB032462: AB_2216805, HPA051312: " "unprognostic (5.31e-2)" "unprognostic (2.65e-1)" "unprognostic (6.92e-2)" "prognostic favorable (5.95e-4)" "unprognostic (1.15e-1)" "unprognostic (2.67e-2)" "unprognostic (2.48e-3)" "unprognostic (1.76e-1)" "unprognostic (1.52e-1)" "unprognostic (3.00e-2)" "unprognostic (3.79e-2)" "unprognostic (2.33e-1)" "unprognostic (6.75e-2)" "unprognostic (1.48e-2)" "unprognostic (1.93e-1)" "unprognostic (1.80e-2)" "unprognostic (4.34e-2)" 15.7 16.3 2.7 2.2 6.4 0.8 8.5 5.3 4.2 10.3 6.4 6.6 0.5 9.6 3.2 19.2 13.8 2.9 43.7 3.2 5.3 10.6 3.1 10.7 0.7 7.7 5.6 77.5 27.4 19.5 6.5 5.9 5.9 6.6 2.0 12.3 11.6 2.0 26.2 5.3 1.9 6.8 4.0 5.5 9.0 6.0 4.9 0.8 11.6 11.7 1.7 12.5 10.4 9.8 0.1 0.8 14.3 0.4 1.5 0.5 22.3 7.0 2.2 1.7 4.3 3.6 0.3 0.0 6.4 2.8 0.6 0.3 3.4 5.6 4.5 9.7 2.4 0.1 1.6 1.8 1.9 9.2 1.7 1.5 3.3 0.7 0.1 7.6 0.7 20.5 0.0 17.4 1.1 0.9 1.1 1.1 9.9 1.5 0.9 0.1 0.4 0.0 6.4 0.4 2.5 2.4 0.6 0.6 10.4 7.5 0.3 33.3 0.3 2.8 4.5 0.1 3.3 14.1 6.1 2.6 14.7 8.2 0.6 0.0 0.0 6.3 0.2 0.0 0.6 0.0 0.0 0.2 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.0 0.0 2.7 6.4 5.3 4.2 3.2 5.3 7.7 5.6 5.9 4.0 4.9 9.8 4.2 16.0 8.8 1.0 0.1 2.7 1.2 18.7 4.6 23.8 4.3 3.9 78.1 1.5 9.7 5.5 104.3 13.2 1.6 9.8 1.9 11.3 5.7 8.6 6.1 3.6 10.9 0.0 8.3 10.3 29.0 17.2 3.1 19.3 0.0 5.7 2.2 2.8 2.3 11.8 10.9 1.4 24.4 1.0 1.1 2.8 7.8 0.6 10.6 2.8 1.0 3.9 0.0 8.0 39.1 8.6 4.3 10.9 0.5 5.1 0.0 8.0 11.9 32.5 0.0 2.7 9.4 8.2 6.4 5.0 2.0 3.4 1.7 15.9 1.3 6.0 VN1R1 "V1RL1, VNR19I1, ZVNH1, ZVNR1" ENSG00000178201 "Vomeronasal 1 receptor 1" Q9GZP7 19 57454790-57457142 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Pheromone response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 8.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.5;Cone photoreceptor cells: 2.1;Horizontal cells: 6.7;Oligodendrocyte precursor cells: 2.5;Rod photoreceptor cells: 4.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 2.9;U-266/70: 2.5;U-266/84: 3.3" "Not detected" "Not detected" HPA062209 Uncertain Nucleoplasm,Vesicles NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 62: Horizontal cells - Visual perception" Vesicles Nucleoplasm "HPA062209: " "unprognostic (7.11e-2)" "unprognostic (1.32e-1)" "unprognostic (2.52e-1)" "unprognostic (3.17e-2)" "unprognostic (1.61e-1)" "unprognostic (2.53e-1)" "unprognostic (1.51e-2)" "unprognostic (5.28e-2)" "unprognostic (1.01e-1)" "unprognostic (2.84e-2)" "unprognostic (1.65e-3)" "unprognostic (1.21e-2)" "unprognostic (5.41e-2)" "unprognostic (5.68e-2)" "unprognostic (2.73e-1)" "unprognostic (1.25e-2)" "unprognostic (4.59e-5)" 0.5 1.0 2.2 0.2 2.4 0.3 0.7 4.5 2.4 0.6 1.8 1.2 0.0 0.5 2.2 0.6 0.8 0.3 2.0 2.3 1.9 1.2 1.0 0.8 0.4 1.8 1.9 1.2 0.6 1.1 3.4 0.6 1.4 1.3 0.3 8.2 0.9 0.6 2.3 1.7 0.7 0.3 1.3 1.1 0.5 1.3 1.9 0.4 1.7 2.7 0.3 0.9 0.6 2.2 0.2 0.0 0.8 0.9 0.0 0.2 0.4 0.2 0.3 0.2 0.8 0.0 0.1 0.1 0.4 0.1 0.1 0.0 0.1 0.1 0.3 0.0 2.9 0.4 0.0 0.3 0.1 0.2 0.5 0.3 0.3 0.0 0.1 0.4 0.1 0.3 0.1 0.4 0.4 0.1 0.2 0.9 0.2 0.0 0.3 0.2 0.5 0.4 0.2 0.5 1.5 0.6 0.0 0.2 0.0 0.4 0.4 0.3 0.0 0.6 0.1 0.1 0.3 2.5 3.3 0.2 0.2 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.4 4.5 2.4 2.3 1.9 1.8 1.9 1.4 1.3 1.9 2.2 0.4 0.0 1.1 0.0 0.4 0.0 0.1 0.0 0.0 4.5 0.2 0.0 0.3 0.0 0.6 0.0 2.1 0.2 1.4 0.0 0.0 0.3 0.0 0.2 0.1 0.6 0.0 0.4 1.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.3 0.1 6.7 0.9 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 1.1 0.0 2.5 0.3 0.1 0.0 0.7 0.0 0.3 0.1 0.0 0.0 4.4 0.0 0.6 0.3 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.1 0.2 VNN1 Tiff66 ENSG00000112299 "Vanin 1" O95497 6 132680849-132714055 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "gallbladder: 89.2;intestine: 136.3;liver: 218.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 50.1;Ductal cells: 244.2;Hepatocytes: 70.6;Pancreatic endocrine cells: 98.0;Proximal enterocytes: 61.7" "Cancer enhanced" "Detected in many" "liver cancer: 41.5" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "classical monocyte: 13.7;non-classical monocyte: 11.9" "Group enriched" "Detected in many" 80 "dendritic cells: 5.0;granulocytes: 8.5;monocytes: 13.7" "Cell line enhanced" "Detected in some" "A-431: 2.5;CAPAN-2: 2.5;EFO-21: 8.7;HBEC3-KT: 2.3;LHCN-M2: 2.5" "Region enhanced" "Detected in single" "white matter: 2.4" "Not detected" "Not detected" "HPA046103, HPA064145" Approved Approved Vesicles "Intracellular and membrane" NA NA 980000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 38: EFO-21 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" Vesicles "HPA046103: , HPA064145: AB_2685197" "unprognostic (9.53e-2)" "unprognostic (5.01e-2)" "unprognostic (9.95e-2)" "unprognostic (1.35e-3)" "unprognostic (6.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.20e-1)" "unprognostic (4.20e-2)" "unprognostic (2.06e-2)" "unprognostic (3.64e-2)" "unprognostic (2.11e-2)" "unprognostic (4.62e-1)" "prognostic unfavorable (2.52e-4)" "unprognostic (2.26e-2)" "unprognostic (4.42e-2)" "unprognostic (2.16e-1)" "unprognostic (2.34e-1)" 2.7 0.6 0.3 3.1 0.6 9.4 1.1 0.5 1.5 1.0 0.0 6.2 136.3 8.9 0.2 0.6 2.6 89.2 0.6 0.2 0.3 21.7 218.7 4.7 2.5 0.6 0.3 0.3 1.4 0.1 0.1 2.7 1.2 0.3 1.8 1.0 2.3 0.2 0.3 0.9 79.5 0.9 0.2 10.1 1.5 0.5 0.5 0.6 0.4 1.1 2.5 1.6 0.7 0.9 2.5 0.0 0.3 0.1 0.0 0.7 0.5 0.2 0.2 0.0 0.0 0.0 2.5 0.1 8.7 0.0 0.4 0.0 0.0 2.3 0.6 0.0 0.0 0.1 0.1 1.4 1.3 0.2 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.5 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.1 1.1 0.5 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.6 0.0 0.2 0.1 0.2 0.0 0.1 0.2 0.1 0.3 3.0 13.7 0.0 0.0 8.0 0.0 0.0 0.0 0.0 5.0 0.1 0.0 0.0 8.5 0.0 11.9 0.2 0.0 3.8 0.3 0.6 0.5 1.5 0.2 0.3 0.6 0.3 1.2 0.2 0.5 0.9 0.0 0.0 3.0 0.0 0.3 1.3 0.2 14.9 0.0 0.0 1.2 0.4 0.2 50.1 11.4 1.8 0.0 0.1 0.2 12.5 0.0 244.2 0.0 7.6 4.1 0.2 0.0 0.0 0.0 19.4 0.1 0.3 4.6 39.6 0.0 0.0 1.1 70.6 18.1 0.0 0.0 11.2 22.4 12.0 3.9 0.0 0.0 23.1 0.0 0.0 17.6 0.0 0.0 0.0 0.0 98.0 1.6 0.0 0.5 6.6 61.7 21.9 16.0 0.0 0.0 0.4 1.1 0.1 0.0 0.1 0.1 0.1 0.5 0.0 2.0 14.7 VPS13D "FLJ10619, KIAA0453" ENSG00000048707 "Vacuolar protein sorting 13 homolog D" Q5THJ4 1 12230030-12512047 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 181.4;Inhibitory neurons: 149.2;Late spermatids: 208.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027332, HPA051621" Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 17: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Vesicles" Cytosol "HPA027332: AB_2672223, HPA051621: AB_2681555" "unprognostic (2.97e-1)" "unprognostic (8.47e-2)" "unprognostic (2.89e-2)" "unprognostic (2.84e-2)" "unprognostic (9.74e-2)" "unprognostic (1.75e-2)" "unprognostic (1.66e-1)" "unprognostic (1.53e-3)" "unprognostic (3.33e-1)" "unprognostic (2.00e-2)" "unprognostic (1.57e-1)" "unprognostic (7.77e-2)" "prognostic favorable (7.42e-12)" "unprognostic (5.13e-1)" "unprognostic (1.72e-1)" "unprognostic (4.04e-2)" "unprognostic (8.31e-2)" 10.9 6.9 14.3 4.4 17.2 5.0 10.3 14.5 17.9 13.7 18.1 12.2 3.8 8.1 8.7 12.6 8.9 5.3 21.9 15.8 14.5 10.5 10.4 8.8 6.4 14.6 16.5 8.9 10.9 13.4 7.7 5.3 14.3 17.4 6.4 14.1 10.8 9.3 18.1 24.7 8.7 6.0 13.4 9.3 11.1 6.1 17.8 6.6 15.5 15.3 6.2 9.6 10.6 16.6 9.3 5.2 5.8 4.4 15.1 11.9 2.7 4.4 7.7 7.4 7.0 3.5 6.4 8.7 5.4 12.6 6.2 8.3 10.1 8.7 10.3 4.7 3.4 7.4 8.1 2.8 6.3 10.8 3.7 10.1 11.9 9.5 9.3 9.2 12.0 8.2 15.5 4.3 6.9 4.3 6.4 4.2 2.3 5.0 6.5 5.5 6.9 2.6 5.3 5.4 2.8 3.8 12.9 9.4 9.0 5.4 8.1 3.6 13.1 4.6 4.7 12.0 3.7 3.8 3.3 13.4 5.2 7.5 7.1 3.2 0.7 0.5 1.1 0.7 1.2 0.9 1.2 0.8 0.6 1.6 1.1 0.9 0.9 0.7 0.5 1.5 0.6 0.3 14.3 17.2 14.5 17.9 15.8 14.5 14.6 16.5 14.3 13.4 17.8 16.6 28.9 19.2 23.4 111.0 19.8 21.7 45.1 23.2 19.9 38.1 18.8 12.8 68.0 14.3 35.7 18.4 73.0 8.4 20.3 24.7 3.9 9.1 83.1 20.6 23.5 23.0 14.4 9.4 181.4 14.4 7.2 19.4 28.1 48.1 12.6 26.3 17.9 21.2 11.5 47.1 149.2 15.1 18.3 17.3 15.5 208.7 23.0 17.5 12.4 79.6 16.7 23.0 17.5 78.4 107.4 17.0 11.2 21.8 11.8 32.0 18.2 9.8 32.0 34.1 46.0 23.4 46.5 18.8 12.3 38.2 31.4 14.8 21.4 20.3 15.5 37.3 VPS25 "DERP9, EAP20, MGC10540" ENSG00000131475 "Vacuolar protein sorting 25 homolog" Q9BRG1 17 42773449-42779599 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004978, HPA021992, HPA052217, HPA057284" Uncertain Supported Vesicles NA Yes "Cluster 31: Non-specific - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 10: Non-specific - Unknown function" Vesicles "CAB004978: AB_426095, HPA021992: , HPA052217: AB_2681765, HPA057284: AB_2683397" "unprognostic (3.63e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.18e-4)" "unprognostic (7.37e-2)" "unprognostic (7.57e-2)" "unprognostic (9.83e-3)" "unprognostic (2.76e-3)" "unprognostic (5.84e-2)" "unprognostic (1.25e-1)" "unprognostic (2.90e-1)" "unprognostic (8.10e-3)" "unprognostic (3.88e-1)" "unprognostic (2.39e-3)" "unprognostic (1.15e-1)" "unprognostic (1.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.91e-2)" 36.6 40.3 32.8 32.5 33.0 44.3 53.3 34.8 36.8 41.6 36.6 61.9 53.8 35.5 65.3 91.4 58.9 33.4 43.5 32.9 33.2 70.1 68.6 31.8 37.8 32.9 32.8 33.2 49.0 72.3 27.6 46.7 33.5 40.2 68.4 31.2 48.7 36.5 51.3 50.5 45.4 42.8 33.5 37.1 50.0 27.4 33.8 51.3 40.9 41.3 57.2 44.8 44.3 34.0 67.2 136.6 101.8 62.1 126.9 86.5 94.5 83.0 117.1 167.5 116.3 117.9 77.0 66.8 135.8 122.0 88.5 68.7 142.2 181.8 107.9 61.2 178.7 50.6 87.0 177.5 131.0 95.7 64.6 118.2 115.4 148.9 158.0 99.1 106.7 79.0 175.6 65.5 102.1 96.5 138.8 105.2 78.9 152.0 95.3 51.1 123.3 108.7 202.6 75.8 86.3 66.7 46.8 60.1 129.6 155.8 138.4 100.2 58.0 105.7 68.4 60.0 90.3 64.0 39.4 97.9 92.7 64.5 79.6 85.1 76.9 106.7 38.8 89.0 39.9 48.8 42.4 46.4 80.3 46.6 42.3 40.7 44.9 78.9 82.7 54.1 43.1 59.6 32.8 33.0 34.8 36.8 32.9 33.2 32.9 32.8 33.5 33.5 33.8 34.0 26.3 25.6 36.3 4.2 25.3 13.9 41.0 88.3 16.5 24.1 44.4 46.6 26.9 51.5 65.7 62.5 14.6 136.1 22.0 74.3 133.1 135.9 2.6 61.8 48.5 35.4 41.0 47.9 3.5 152.4 186.5 40.8 40.8 55.9 29.2 21.5 29.6 46.4 102.3 23.5 3.5 70.5 85.5 34.5 12.7 5.6 27.7 33.0 42.7 0.0 46.7 56.1 44.3 2.5 4.7 134.4 75.7 30.5 40.9 44.4 83.5 93.6 74.9 29.5 32.9 13.5 69.9 42.8 46.7 61.9 22.9 121.6 22.8 69.9 63.4 53.5 VPS29 "DC15, DC7, PEP11" ENSG00000111237 "VPS29 retromer complex component" Q9UBQ0 12 110491083-110502111 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039748 Uncertain Supported Vesicles,Cytosol NA NA 110000 "Cluster 51: Monocytes - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 10: Non-specific - Unknown function" "Vesicles, Cytosol" "HPA039748: AB_10674426" "unprognostic (9.46e-2)" "unprognostic (3.46e-3)" "unprognostic (2.16e-2)" "unprognostic (2.58e-1)" "unprognostic (3.08e-1)" "unprognostic (2.26e-2)" "prognostic unfavorable (2.79e-5)" "unprognostic (1.52e-1)" "unprognostic (3.37e-2)" "prognostic favorable (7.70e-4)" "unprognostic (1.64e-1)" "unprognostic (2.10e-3)" "unprognostic (2.96e-1)" "unprognostic (2.04e-2)" "unprognostic (2.11e-1)" "unprognostic (5.57e-2)" "unprognostic (4.29e-3)" 61.1 62.7 45.6 57.0 47.0 96.2 59.2 46.2 61.8 50.3 47.0 76.4 64.1 52.9 89.5 71.1 50.3 51.1 73.8 48.7 48.3 79.2 77.6 54.9 69.7 47.2 46.3 47.1 56.6 54.8 53.7 47.3 47.4 62.7 79.0 99.6 58.5 71.3 127.3 46.8 65.7 67.1 48.0 76.5 62.8 32.6 46.1 63.2 54.1 100.8 72.0 65.1 50.6 51.1 103.5 98.6 91.9 65.6 100.4 98.7 72.6 94.9 98.1 93.9 84.2 100.0 87.0 94.0 97.1 94.3 87.7 95.5 123.1 88.0 97.0 112.2 98.9 115.4 122.6 83.0 87.4 139.5 97.1 66.0 73.3 79.3 87.4 114.1 166.0 116.6 112.1 85.5 170.0 51.9 110.3 196.4 52.6 90.9 124.8 72.2 93.5 131.8 157.0 149.7 98.1 51.8 107.9 94.0 122.8 78.5 128.6 106.0 94.0 80.6 53.4 112.9 113.0 58.0 87.5 112.1 93.9 130.8 87.8 246.2 262.7 259.4 139.1 356.8 155.3 195.9 175.5 164.9 318.3 158.7 159.8 156.8 178.7 202.9 405.4 214.0 224.8 385.1 45.6 47.0 46.2 61.8 48.7 48.3 47.2 46.3 47.4 48.0 46.1 51.1 138.8 76.9 96.2 21.2 93.7 143.5 172.6 395.9 70.6 39.0 93.4 109.2 282.4 90.1 209.7 101.2 27.1 192.8 116.5 156.3 289.5 231.0 56.8 94.7 79.8 125.0 83.2 147.5 30.2 179.8 187.6 120.2 60.1 104.1 153.9 78.1 94.9 158.7 409.9 42.1 26.7 149.8 248.2 158.0 296.1 82.6 92.2 178.7 177.9 30.9 295.2 107.9 101.0 22.6 30.4 217.9 182.2 105.7 94.8 157.4 142.2 404.7 131.1 111.8 157.8 81.9 212.1 256.4 148.4 108.3 173.0 178.8 111.2 105.8 164.5 187.7 VPS36 "C13orf9, CGI-145, Eap45" ENSG00000136100 "Vacuolar protein sorting 36 homolog" Q86VN1 13 52412602-52450634 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 265.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039734, HPA043947" Approved Supported "Vesicles,Lysosomes,Plasma membrane,Cell Junctions" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 31: Skin - Epidermis development" "Cluster 43: THP-1 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Vesicles, Lysosomes" "Plasma membrane, Cell Junctions" "HPA039734: AB_2676652, HPA043947: AB_2678744" "unprognostic (2.43e-1)" "unprognostic (1.44e-1)" "unprognostic (2.80e-1)" "unprognostic (2.94e-1)" "unprognostic (1.56e-1)" "unprognostic (2.32e-1)" "unprognostic (6.57e-2)" "unprognostic (7.84e-2)" "unprognostic (3.96e-3)" "unprognostic (1.19e-2)" "unprognostic (9.37e-2)" "unprognostic (5.57e-2)" "prognostic favorable (9.91e-6)" "unprognostic (6.47e-3)" "unprognostic (1.83e-1)" "unprognostic (1.94e-1)" "unprognostic (9.83e-2)" 17.1 15.1 10.1 16.8 11.5 8.6 26.1 14.0 16.3 20.0 9.6 24.5 27.6 18.7 12.2 23.7 16.8 16.6 24.0 11.8 10.1 25.4 23.6 19.9 19.5 12.4 11.0 17.9 17.9 23.3 11.0 25.0 12.8 21.8 27.5 43.1 25.2 18.3 23.4 51.1 27.7 20.7 9.9 24.1 18.1 4.0 12.1 22.3 22.5 26.2 20.7 18.9 21.3 12.1 7.3 11.8 20.4 13.5 21.1 29.3 17.8 16.7 12.5 16.1 9.6 14.3 22.9 25.5 8.6 23.8 10.6 20.1 16.6 19.7 18.0 19.3 16.0 30.2 18.7 12.8 25.3 40.2 31.4 20.5 37.9 11.2 18.0 18.0 16.6 33.6 22.7 21.8 31.8 9.6 30.4 40.6 19.5 29.0 6.3 31.0 11.9 15.9 28.7 18.9 10.4 22.0 11.9 27.3 25.9 24.0 15.9 67.1 26.3 10.3 12.6 10.3 19.1 16.3 22.0 26.8 10.6 28.4 24.7 15.6 14.6 12.3 12.3 16.3 19.8 15.3 13.5 15.4 15.6 13.0 12.2 13.1 3.6 21.6 22.7 16.3 16.0 13.7 10.1 11.5 14.0 16.3 11.8 10.1 12.4 11.0 12.8 9.9 12.1 12.1 54.2 83.3 51.5 41.1 49.9 42.8 48.9 57.6 62.0 132.2 51.6 72.8 80.8 38.6 47.7 33.1 120.9 60.2 83.4 62.6 68.4 35.4 1.2 28.0 45.9 55.7 49.8 31.1 57.0 29.3 43.0 46.6 36.7 37.0 44.3 44.9 38.2 54.0 43.8 52.2 54.6 64.1 40.7 44.0 29.1 3.7 49.7 47.1 28.4 36.5 60.8 39.8 59.8 44.7 40.7 29.8 63.0 52.3 55.0 65.4 77.4 78.5 33.2 265.8 46.0 52.7 76.1 15.3 25.9 83.5 58.2 38.2 48.2 40.6 58.6 45.4 VPS37A "FLJ32642, HCRP1, PQBP2, SPG53" ENSG00000155975 "VPS37A subunit of ESCRT-I" Q8NEZ2 8 17246931-17302427 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024705, HPA024781" Supported Approved Vesicles,Centrosome,Cytosol NA NA "Cluster 46: Basophils - DNA binding" "Cluster 23: Testis - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "Centrosome, Cytosol" "HPA024705: AB_10601776, HPA024781: AB_10602100" "unprognostic (8.28e-2)" "unprognostic (1.84e-1)" "unprognostic (9.39e-3)" "unprognostic (3.91e-1)" "unprognostic (2.10e-1)" "unprognostic (6.31e-2)" "unprognostic (5.88e-3)" "unprognostic (2.28e-2)" "unprognostic (1.43e-1)" "unprognostic (3.17e-1)" "unprognostic (1.02e-1)" "unprognostic (2.88e-1)" "unprognostic (5.06e-2)" "unprognostic (1.98e-2)" "unprognostic (1.31e-1)" "unprognostic (2.66e-1)" "unprognostic (2.18e-1)" 18.9 19.4 11.9 14.8 15.1 15.4 18.5 28.7 17.5 21.1 5.0 16.8 20.9 19.4 14.3 20.2 13.7 16.8 36.2 10.1 13.6 25.0 27.8 16.2 14.2 11.2 12.5 18.4 17.5 33.8 12.4 29.7 12.1 20.2 17.2 55.0 12.5 23.2 39.4 14.7 17.5 24.4 10.0 12.3 14.5 32.3 12.2 17.5 18.9 31.2 15.2 25.1 15.0 18.4 17.2 27.3 24.0 21.7 51.8 41.5 25.8 60.8 50.2 53.9 45.9 17.6 16.2 14.6 31.6 48.7 50.1 16.7 27.2 26.4 63.8 15.1 7.8 26.5 13.7 20.2 59.7 11.3 25.1 39.7 50.2 50.4 51.5 38.0 38.7 22.7 20.2 36.8 57.7 11.7 32.0 26.9 23.4 38.2 14.2 15.4 26.5 17.6 45.8 23.4 27.1 14.4 23.8 23.9 37.9 47.1 15.6 22.2 33.4 33.1 16.7 47.6 32.0 12.0 25.0 17.2 37.5 19.9 33.8 34.0 17.2 16.5 13.9 13.1 17.1 10.5 13.4 13.6 13.4 10.8 12.0 14.8 17.6 24.5 12.4 11.8 13.3 14.1 11.9 15.1 28.7 17.5 10.1 13.6 11.2 12.5 12.1 10.0 12.2 18.4 31.8 16.0 15.6 19.6 21.2 39.5 32.7 33.1 18.8 26.4 19.3 13.5 40.7 14.3 25.8 7.3 58.4 36.1 20.5 15.8 37.2 29.3 93.2 20.9 29.0 24.6 18.0 26.1 32.4 15.5 59.2 27.0 15.8 28.4 9.5 16.8 24.3 23.1 44.6 21.9 30.7 16.6 30.5 17.5 22.7 39.6 25.7 25.3 21.4 20.6 22.4 25.8 15.5 24.1 34.0 31.2 13.1 25.9 21.5 50.6 27.8 48.8 18.8 60.2 26.3 21.5 36.6 111.6 43.4 22.5 37.8 113.0 22.7 17.1 14.6 52.6 VPS37C FLJ20847 ENSG00000167987 "VPS37C subunit of ESCRT-I" A5D8V6 11 61130257-61161615 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 1.4;eosinophil: 1.7;intermediate monocyte: 2.6;myeloid DC: 1.0;neutrophil: 3.8;non-classical monocyte: 2.4" "Group enriched" "Detected in many" 5 "dendritic cells: 1.0;granulocytes: 3.8;monocytes: 2.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043348 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles Nucleoplasm "HPA043348: AB_10794658" "unprognostic (1.97e-1)" "unprognostic (1.35e-1)" "unprognostic (2.50e-1)" "unprognostic (7.95e-3)" "unprognostic (3.38e-1)" "unprognostic (9.01e-2)" "prognostic unfavorable (5.85e-5)" "unprognostic (7.42e-2)" "unprognostic (1.14e-1)" "unprognostic (3.00e-1)" "unprognostic (3.41e-2)" "unprognostic (3.17e-2)" "prognostic favorable (2.37e-7)" "unprognostic (1.99e-1)" "unprognostic (1.08e-1)" "unprognostic (3.85e-1)" "unprognostic (7.05e-2)" 14.1 13.8 11.5 13.2 10.9 10.3 14.0 10.0 12.2 14.3 11.9 17.7 17.1 15.9 5.2 22.0 12.5 11.2 15.8 12.6 9.9 16.8 10.7 14.5 8.1 11.9 11.6 14.1 24.1 11.9 20.1 14.1 10.5 20.9 10.5 22.7 23.3 14.6 23.6 22.2 15.5 14.5 9.6 13.3 27.7 15.3 12.0 6.2 12.1 11.8 10.0 18.3 15.9 11.4 33.8 13.1 16.7 16.1 8.0 16.6 37.2 16.4 44.0 23.9 16.2 15.7 15.6 8.8 22.5 22.5 19.7 18.5 15.2 17.3 12.3 19.2 11.4 11.2 9.0 17.8 25.7 9.0 13.7 15.0 26.3 20.6 25.7 14.3 15.8 6.0 29.6 14.6 16.4 41.1 2.0 13.7 20.6 14.7 18.8 3.1 7.2 21.4 18.9 17.2 10.3 25.1 16.4 52.2 28.8 14.0 49.5 22.2 12.1 23.9 17.2 24.4 20.8 6.9 10.0 7.2 21.6 11.1 16.5 0.4 1.4 1.7 0.3 2.6 0.4 0.5 0.2 0.4 1.0 0.5 0.3 0.1 3.8 0.2 2.4 0.1 0.2 0.7 11.5 10.9 10.0 12.2 12.6 9.9 11.9 11.6 10.5 9.6 12.0 11.4 6.3 16.0 6.0 5.9 4.1 12.5 14.3 9.4 10.2 5.8 14.9 9.3 7.5 12.8 10.0 12.9 10.4 30.6 1.2 15.6 11.7 17.4 8.9 5.0 4.0 11.2 16.3 4.2 8.9 19.8 20.9 10.6 13.7 6.8 0.0 5.1 7.1 6.7 17.3 25.2 7.1 18.3 8.2 13.7 11.4 6.5 7.8 13.9 7.2 13.1 12.3 11.5 2.1 4.5 8.3 21.7 11.3 13.5 2.2 17.7 19.0 7.2 12.2 41.7 0.0 6.7 9.2 12.9 16.7 8.4 19.9 35.2 2.9 7.4 10.6 14.5 VPS37D "MGC35352, WBSCR24" ENSG00000176428 "VPS37D subunit of ESCRT-I" Q86XT2 7 73667831-73672112 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 13.0;Collecting duct cells: 11.0;Distal tubular cells: 9.8;Muller glia cells: 13.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SH-SY5Y: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040978 Uncertain Approved Vesicles NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" Vesicles "HPA040978: AB_10805833" "unprognostic (2.98e-2)" "unprognostic (2.17e-1)" "unprognostic (1.13e-2)" "unprognostic (7.85e-2)" "unprognostic (1.93e-1)" "unprognostic (3.85e-2)" "unprognostic (2.54e-1)" "unprognostic (3.94e-1)" "unprognostic (8.80e-2)" "unprognostic (1.97e-1)" "prognostic favorable (2.07e-5)" "unprognostic (4.19e-2)" "prognostic favorable (5.80e-9)" "unprognostic (9.63e-2)" "unprognostic (1.67e-1)" "unprognostic (1.25e-2)" "unprognostic (1.43e-1)" 1.8 1.3 8.4 0.3 8.7 0.2 2.4 7.9 12.1 6.1 3.5 3.1 1.8 3.7 2.8 0.8 3.6 1.4 2.3 8.9 7.9 11.3 9.6 1.0 0.2 7.9 7.3 4.2 4.0 2.7 3.3 0.3 8.0 3.7 0.2 1.6 3.2 2.0 1.3 2.5 1.9 0.7 6.3 0.9 2.1 7.1 8.6 0.3 3.4 0.5 0.1 2.2 2.8 7.0 0.5 2.3 1.8 3.8 1.2 2.4 1.1 1.0 1.5 0.8 1.0 0.2 0.7 0.8 0.9 1.3 2.1 0.3 1.9 0.9 0.2 0.3 2.0 0.0 0.2 2.6 3.2 0.0 1.1 1.9 0.5 1.1 0.3 3.5 0.9 3.2 1.1 0.2 1.1 2.8 0.6 0.0 1.2 0.7 3.3 0.1 0.0 0.1 3.0 0.2 3.7 11.8 0.0 1.6 2.3 0.3 3.8 0.1 1.3 2.2 3.0 1.3 0.8 1.4 0.1 1.1 5.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 8.7 7.9 12.1 8.9 7.9 7.9 7.3 8.0 6.3 8.6 7.0 2.4 0.0 0.0 1.3 0.2 1.0 0.8 0.3 0.6 13.0 3.4 3.8 1.8 1.5 0.1 11.0 0.0 0.2 0.1 0.2 9.8 4.0 1.1 3.6 3.1 1.1 4.9 0.0 1.6 0.8 0.4 1.6 0.0 5.1 0.0 5.9 1.8 5.3 0.1 0.0 2.7 0.4 2.0 0.0 0.4 0.9 1.8 0.2 5.4 1.0 0.6 13.9 0.0 1.0 0.9 1.8 1.4 2.6 0.3 1.0 2.0 8.3 0.2 5.3 0.0 0.9 2.7 0.6 8.3 0.1 1.1 0.3 0.2 0.9 0.7 0.4 VPS4B "SKD1, SKD1B, VPS4-2" ENSG00000119541 "Vacuolar protein sorting 4 homolog B" O75351 18 63389190-63422483 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040393, CAB046445, HPA057649" Approved Approved "Vesicles,Intermediate filaments" No No 32000 "Cluster 1: Neutrophils - Mixed function" "Cluster 37: Intestine - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" Vesicles "Intermediate filaments" "CAB046445: AB_10603252, HPA040393: , HPA057649: AB_2683489" "unprognostic (8.54e-2)" "unprognostic (1.06e-1)" "unprognostic (1.85e-3)" "unprognostic (5.59e-2)" "unprognostic (1.71e-1)" "unprognostic (9.47e-2)" "unprognostic (1.75e-1)" "unprognostic (1.79e-1)" "unprognostic (4.54e-2)" "unprognostic (9.10e-2)" "unprognostic (1.94e-3)" "unprognostic (1.67e-1)" "prognostic favorable (1.23e-4)" "unprognostic (4.59e-1)" "unprognostic (1.40e-1)" "unprognostic (4.08e-1)" "unprognostic (1.21e-1)" 24.2 18.3 10.5 25.5 13.1 52.6 28.8 13.2 17.8 26.8 9.3 42.3 35.1 22.7 19.5 75.4 18.6 23.7 16.2 10.3 14.6 23.8 28.4 23.8 31.2 13.5 15.9 19.3 17.3 27.8 11.5 28.7 14.0 23.4 37.0 7.0 24.7 19.5 11.0 32.3 36.4 21.0 12.6 28.8 32.5 12.1 12.5 31.4 28.5 13.0 39.1 30.2 31.1 15.6 57.1 21.9 22.4 24.5 33.5 47.1 38.9 48.6 45.5 36.4 39.2 15.7 39.4 54.1 31.2 35.7 30.9 119.6 26.8 53.1 47.5 40.6 22.3 27.6 27.8 23.7 48.6 94.5 56.8 43.1 80.3 32.3 56.2 36.5 33.9 31.0 14.3 49.4 52.1 20.2 59.9 29.2 23.2 22.7 32.3 48.8 47.2 52.4 45.6 66.2 38.2 33.6 36.9 35.4 55.3 28.3 34.2 50.5 52.8 55.4 27.3 21.6 32.7 163.6 86.5 69.3 31.9 44.0 42.3 163.6 54.6 125.0 52.2 56.5 49.0 64.8 54.3 54.2 46.2 73.4 48.2 51.1 185.9 68.4 76.5 45.6 66.7 56.6 10.5 13.1 13.2 17.8 10.3 14.6 13.5 15.9 14.0 12.6 12.5 15.6 52.0 115.4 57.4 21.5 62.4 68.8 47.2 66.5 44.9 37.0 54.4 46.0 39.5 47.1 72.4 33.1 22.9 70.0 92.2 142.0 45.0 48.0 113.3 92.2 74.0 44.6 45.5 27.8 27.3 42.1 56.7 51.0 47.4 145.5 59.3 37.7 36.8 55.8 46.4 43.7 29.6 76.8 67.1 58.8 33.0 15.5 49.0 58.0 32.0 18.7 53.4 39.2 76.2 18.6 49.5 91.3 120.7 36.5 42.1 43.1 61.8 57.9 85.1 31.5 59.2 45.6 54.7 30.1 29.4 87.5 83.4 140.4 67.4 56.5 72.6 79.5 VPS51 "ANG2, ANG3, C11orf2, C11orf3, FFR" ENSG00000149823 "VPS51 subunit of GARP complex" Q9UID3 11 65089324-65111862 "Disease related genes, Predicted intracellular proteins" "Lipid transport, Protein transport, Transport" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039650, HPA061447" Uncertain Approved "Nucleoli,Golgi apparatus,Vesicles" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 50: Non-specific - Ribosome" "Cluster 25: RPMI-8226 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Golgi apparatus, Vesicles" Nucleoli "HPA039650: AB_10673147, HPA061447: AB_2684521" "unprognostic (2.36e-2)" "unprognostic (7.58e-2)" "unprognostic (8.35e-2)" "unprognostic (1.56e-1)" "unprognostic (2.11e-2)" "unprognostic (1.64e-1)" "unprognostic (9.72e-2)" "unprognostic (1.52e-1)" "unprognostic (2.58e-1)" "unprognostic (1.17e-1)" "unprognostic (2.03e-3)" "unprognostic (1.56e-1)" "prognostic favorable (2.41e-9)" "unprognostic (7.77e-3)" "unprognostic (4.63e-2)" "unprognostic (2.85e-1)" "unprognostic (2.18e-1)" 48.5 37.8 19.0 34.9 23.1 60.9 46.6 22.0 30.7 45.6 20.4 55.4 52.9 54.4 7.3 42.5 46.1 20.3 45.3 22.5 15.5 33.7 36.2 34.2 48.6 18.5 18.6 83.8 120.3 37.4 28.6 22.2 20.2 38.1 25.1 20.3 65.5 27.7 84.2 71.2 49.7 22.7 14.3 40.9 70.3 28.4 17.2 46.7 39.7 42.9 32.5 45.2 38.1 21.5 71.8 74.5 35.7 44.4 15.5 38.5 72.1 27.5 53.2 52.6 38.8 55.2 88.7 118.0 76.1 51.4 27.3 60.0 37.9 59.3 19.2 69.6 62.1 72.5 72.6 55.1 51.3 77.1 65.0 66.8 39.9 39.0 32.1 41.6 58.4 55.0 73.6 82.9 21.7 95.1 105.8 83.0 59.8 30.7 61.5 67.5 17.5 150.7 36.2 76.2 61.5 87.8 20.7 110.9 71.8 21.0 93.7 39.1 48.1 35.2 32.0 45.4 39.7 115.7 92.2 68.9 39.9 28.0 26.3 10.6 15.0 15.4 17.9 15.8 21.2 22.4 25.2 27.1 22.1 21.2 23.3 20.7 8.0 30.6 16.0 19.1 17.7 18.3 19.0 23.1 22.0 30.7 22.5 15.5 18.5 18.6 20.2 14.3 17.2 21.5 49.8 19.2 47.7 18.9 77.3 49.1 66.3 46.0 58.6 64.7 76.5 67.8 5.8 44.3 27.8 31.3 29.2 78.4 73.7 156.5 62.6 49.2 77.5 25.6 35.0 46.5 95.8 50.5 21.8 120.5 79.4 38.8 45.9 34.4 37.5 47.3 55.3 52.5 45.5 67.3 24.1 110.0 32.6 54.0 30.6 222.4 53.4 36.1 49.8 15.9 71.3 65.9 89.6 21.6 28.0 51.2 144.4 54.5 66.4 45.1 158.7 75.9 16.1 52.5 26.3 49.3 44.4 40.3 31.4 52.3 54.8 115.3 64.0 61.5 170.5 51.0 VPS53 "FLJ10979, HCCS1" ENSG00000141252 "VPS53 subunit of GARP complex" Q5VIR6 17 508503-721717 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Epilepsy, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 270.0;Late spermatids: 203.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022988, HPA024446" Approved Supported "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" Cytosol "HPA022988: AB_1848679, HPA024446: AB_1848680" "unprognostic (8.62e-3)" "unprognostic (7.98e-2)" "unprognostic (2.09e-1)" "prognostic favorable (1.08e-5)" "unprognostic (1.39e-2)" "unprognostic (9.08e-3)" "unprognostic (3.12e-1)" "unprognostic (9.67e-2)" "unprognostic (1.43e-1)" "unprognostic (2.72e-1)" "prognostic favorable (1.56e-5)" "unprognostic (1.53e-2)" "unprognostic (1.82e-2)" "unprognostic (1.89e-2)" "unprognostic (2.81e-1)" "unprognostic (4.82e-2)" "unprognostic (1.31e-1)" 4.3 4.7 7.0 3.0 5.9 20.5 4.6 21.4 10.3 5.2 2.8 4.5 3.7 4.4 3.4 9.0 4.0 3.6 4.3 8.2 3.3 4.0 4.5 5.1 4.9 3.0 3.9 5.3 4.5 6.4 6.0 4.6 4.2 4.6 5.9 8.1 4.7 5.0 7.0 7.1 4.0 6.1 0.9 4.5 5.0 14.6 4.0 4.9 7.6 5.1 5.2 4.1 4.8 9.4 12.9 26.5 7.6 8.3 12.4 9.5 5.5 6.4 9.4 15.8 15.4 12.6 5.8 7.8 5.9 19.9 10.0 10.9 16.5 13.9 23.1 6.7 11.4 5.0 17.2 8.1 6.1 6.6 9.2 11.1 7.8 14.7 9.8 6.4 11.7 9.7 9.1 9.1 14.9 8.9 4.3 5.1 6.2 5.6 6.9 10.5 3.9 5.2 8.0 10.4 7.6 6.1 12.4 4.3 5.4 7.5 6.5 3.5 7.9 6.8 5.4 12.5 7.0 4.3 3.3 4.8 11.5 5.2 8.6 8.1 1.9 4.4 2.4 2.3 1.8 2.1 2.2 1.7 1.1 3.0 2.3 1.9 6.1 1.9 5.6 3.0 1.9 0.9 7.0 5.9 21.4 10.3 8.2 3.3 3.0 3.9 4.2 0.9 4.0 9.4 16.0 12.8 25.9 54.5 19.3 25.5 16.5 11.6 19.9 53.3 19.6 9.3 17.4 14.3 21.5 40.5 70.9 10.5 19.9 24.9 1.9 16.7 270.0 23.9 22.2 18.7 24.6 5.0 109.3 18.3 7.9 18.5 26.5 28.1 24.1 18.2 15.7 17.7 21.4 63.9 103.6 27.4 4.1 20.6 19.4 203.9 18.6 21.0 10.6 39.4 27.5 18.3 37.0 48.2 62.5 25.3 15.5 23.0 20.6 18.7 21.0 10.6 24.3 52.2 6.6 31.1 20.7 46.0 35.3 24.6 38.8 8.9 26.8 17.2 22.0 19.6 VRK3 ENSG00000105053 "VRK serine/threonine kinase 3" Q8IV63 19 49976468-50025946 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 135.6" "Group enriched" "Detected in all" 7 "Early spermatids: 557.6;Late spermatids: 1646.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056489 Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 21: OE19 - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" "HPA056489: AB_2683150" "unprognostic (2.09e-1)" "unprognostic (3.14e-2)" "unprognostic (1.26e-1)" "unprognostic (4.94e-3)" "unprognostic (1.23e-1)" "unprognostic (2.22e-3)" "unprognostic (9.78e-2)" "unprognostic (3.47e-1)" "unprognostic (8.79e-2)" "unprognostic (2.48e-1)" "unprognostic (1.31e-2)" "unprognostic (1.43e-1)" "prognostic favorable (1.83e-4)" "unprognostic (9.38e-2)" "unprognostic (2.15e-1)" "unprognostic (1.06e-1)" "prognostic favorable (5.66e-4)" 17.4 23.3 25.9 17.6 26.6 23.6 17.7 26.1 28.6 17.9 30.2 21.9 25.8 15.9 19.5 17.6 33.2 20.9 17.5 25.4 27.9 36.5 35.6 16.9 28.5 27.6 31.1 21.2 22.1 15.9 20.6 16.9 30.4 20.2 22.0 64.8 21.9 15.4 26.9 16.8 32.9 14.1 25.2 26.0 21.6 135.6 27.9 35.6 19.7 17.4 25.7 18.0 16.8 29.3 31.0 31.3 22.6 24.5 29.2 26.9 23.3 21.7 25.7 31.6 34.5 16.8 33.7 37.1 15.2 21.2 22.1 22.5 21.3 18.6 25.5 32.6 43.5 28.9 20.4 29.4 21.9 36.7 48.7 24.2 27.3 18.3 19.2 28.4 26.5 39.9 35.8 53.7 23.2 13.0 49.7 24.5 12.2 54.6 26.7 39.3 23.9 47.6 27.2 32.2 25.3 12.3 21.5 26.0 24.7 20.0 23.9 38.5 20.2 32.2 18.6 13.1 17.1 34.3 47.4 19.6 25.8 22.3 22.5 110.0 42.8 81.1 53.7 46.1 43.3 58.9 48.7 51.9 47.9 53.3 49.2 45.3 112.5 82.7 55.1 45.4 76.1 48.4 25.9 26.6 26.1 28.6 25.4 27.9 27.6 31.1 30.4 25.2 27.9 29.3 19.6 6.4 28.6 10.1 26.6 6.6 16.0 27.2 6.8 34.3 17.9 14.5 8.4 24.3 29.8 14.7 143.9 43.8 27.9 49.9 31.3 31.0 557.6 50.7 12.0 16.0 22.2 38.7 13.9 32.7 38.6 15.5 18.8 26.8 18.3 24.1 28.5 44.5 34.8 32.0 15.9 35.4 34.6 25.4 9.3 1646.8 22.1 22.9 14.2 6.5 40.6 33.2 41.2 10.1 15.3 34.2 67.9 25.9 18.6 20.6 87.5 91.4 71.8 116.0 13.1 12.0 15.2 142.8 52.6 10.5 10.9 57.3 28.0 24.9 36.0 30.1 VSIG1 "GPA34, MGC44287" ENSG00000101842 "V-set and immunoglobulin domain containing 1" Q86XK7 X 108044970-108079184 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "stomach 1: 193.6" "Cell type enriched" "Detected in some" 10 "Gastric mucus-secreting cells: 333.8" "Group enriched" "Detected in many" 17 "lung cancer: 8.7;pancreatic cancer: 17.7;stomach cancer: 31.2" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 12.0;T-reg: 12.9" "Lineage enriched" "Detected in many" 4 "T-cells: 12.9" "Cell line enhanced" "Detected in some" "HBEC3-KT: 3.5;HUVEC TERT2: 7.4;PC-3: 2.3;TIME: 1.7" "Not detected" "Not detected" "HPA001445, HPA036310, HPA036311" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 4: Stomach - Digestion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Vesicles, Cytosol" "HPA001445: AB_10669749, HPA036310: AB_10670795, HPA036311: AB_10673350" "unprognostic (4.33e-3)" "unprognostic (4.60e-2)" "unprognostic (3.22e-2)" "unprognostic (1.60e-1)" "unprognostic (2.51e-1)" "unprognostic (4.80e-2)" "unprognostic (3.25e-2)" "unprognostic (9.79e-2)" "unprognostic (4.58e-1)" "unprognostic (2.35e-2)" "unprognostic (2.11e-2)" "unprognostic (1.25e-1)" "unprognostic (6.31e-7)" "unprognostic (1.48e-1)" "unprognostic (1.07e-1)" "unprognostic (2.19e-2)" "unprognostic (2.23e-3)" 0.0 0.1 0.1 1.3 0.3 0.5 0.1 0.2 0.3 0.0 0.2 0.2 1.2 0.1 0.3 0.2 0.0 8.4 0.0 0.2 0.2 0.1 0.1 1.0 1.9 0.1 0.1 0.0 0.2 0.0 2.6 0.3 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.4 0.5 0.0 0.0 0.8 193.6 47.7 0.1 0.8 0.1 0.0 1.6 8.9 0.1 0.1 0.1 0.6 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.3 0.0 3.5 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.2 0.6 0.0 1.1 0.0 7.4 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.2 0.6 2.3 0.2 0.0 0.0 0.3 0.6 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 1.7 0.1 0.5 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.1 1.0 0.0 3.8 2.8 8.1 3.6 0.0 1.3 12.0 5.8 0.3 0.1 0.1 0.1 12.9 2.6 0.1 0.3 0.2 0.3 0.2 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.2 25.6 11.0 1.0 2.4 0.6 0.9 0.7 0.0 0.9 0.2 0.1 0.5 1.5 0.7 0.0 0.0 0.0 0.1 0.4 0.0 2.9 6.1 1.1 0.1 1.0 0.0 0.0 4.1 4.6 0.0 0.6 333.8 0.2 2.5 0.0 0.0 0.0 0.1 0.0 1.4 0.3 0.0 0.0 0.4 10.8 0.6 0.7 0.0 0.0 0.3 0.1 1.0 0.0 0.1 32.9 0.0 0.0 1.0 0.6 0.0 0.0 0.9 0.8 0.0 1.1 0.2 1.0 0.6 0.0 0.0 0.1 4.5 0.2 0.1 3.8 VSTM1 UNQ3033 ENSG00000189068 "V-set and transmembrane domain containing 1" Q6UX27 19 54040825-54063953 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "bone marrow: 43.2" "Cell type enhanced" "Detected in some" "Early spermatids: 3.4;Late spermatids: 20.3;Macrophages: 4.5;monocytes: 12.4;NK-cells: 3.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 16 "eosinophil: 129.2" "Lineage enriched" "Detected in many" 16 "granulocytes: 129.2" "Cell line enhanced" "Detected in some" "HMC-1: 1.0;hTERT-HME1: 1.0;U-2 OS: 1.0" "Low region specificity" "Detected in all" HPA059365 Approved Vesicles "Secreted to blood" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "HPA059365: " "unprognostic (5.13e-2)" "unprognostic (5.31e-2)" "unprognostic (1.05e-1)" "unprognostic (1.42e-1)" "unprognostic (1.36e-3)" "unprognostic (1.30e-1)" "unprognostic (1.09e-1)" "unprognostic (3.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.59e-1)" "unprognostic (9.47e-2)" "unprognostic (1.31e-5)" "unprognostic (3.73e-1)" "unprognostic (1.14e-1)" "unprognostic (9.74e-2)" "unprognostic (4.67e-2)" 0.2 0.1 0.0 0.2 0.0 43.2 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.4 0.1 0.0 0.0 0.1 0.2 1.0 0.0 0.0 0.0 0.0 1.4 0.0 4.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.4 0.0 3.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 7.4 129.2 0.0 6.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 8.1 0.0 0.0 4.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 3.4 0.2 0.1 0.1 0.0 0.8 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 2.1 0.0 0.4 0.0 0.0 2.5 0.0 20.3 0.0 4.5 0.0 0.0 12.4 0.0 3.1 0.5 0.6 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 VSTM4 "C10orf72, FLJ31737" ENSG00000165633 "V-set and transmembrane domain containing 4" Q8IW00 10 49014236-49115522 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 88.5;Granulosa cells: 96.9;Late spermatids: 140.6;Sertoli cells: 59.2;Theca cells: 44.7" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 22.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 8.6;RH-30: 9.3;SH-SY5Y: 7.9;U-138 MG: 10.6;U-2197: 24.0;U-87 MG: 11.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017279 Uncertain Approved Nucleoplasm,Vesicles "Secreted - unknown location" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Vesicles" "HPA017279: AB_10959519" "unprognostic (8.46e-2)" "unprognostic (5.41e-1)" "unprognostic (1.89e-1)" "unprognostic (2.07e-1)" "unprognostic (1.80e-1)" "unprognostic (2.84e-2)" "unprognostic (1.20e-1)" "unprognostic (6.70e-2)" "unprognostic (1.93e-2)" "unprognostic (2.81e-2)" "unprognostic (3.03e-1)" "unprognostic (1.95e-2)" "unprognostic (2.56e-3)" "unprognostic (1.06e-2)" "unprognostic (1.62e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (4.25e-4)" 18.7 41.5 7.1 3.2 9.0 0.3 9.8 8.0 6.6 22.3 7.7 7.8 2.5 12.3 7.4 7.8 8.5 10.5 12.3 6.2 7.6 12.3 3.9 10.9 3.5 8.9 9.3 35.2 1.5 26.8 5.1 10.4 9.2 13.5 5.6 2.3 3.4 11.7 5.6 4.9 4.9 11.4 8.6 2.3 5.6 9.4 8.4 6.5 27.8 5.9 4.6 12.0 7.5 9.4 0.0 0.0 3.1 0.1 1.3 0.7 0.1 2.6 4.1 0.9 0.2 0.0 0.1 0.1 0.1 6.1 3.4 0.1 0.2 0.0 0.4 3.2 1.4 0.2 0.1 0.1 0.1 0.1 0.0 4.7 0.0 4.2 0.0 0.0 0.0 0.8 8.6 0.1 0.8 0.1 0.0 0.2 0.6 0.0 0.0 0.0 9.3 5.0 0.0 0.1 0.1 7.9 0.1 0.0 0.0 0.4 0.1 0.3 0.0 10.6 1.2 24.0 0.1 0.0 6.8 0.0 11.6 0.1 0.1 0.5 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.5 0.3 0.1 0.1 0.0 0.0 7.1 9.0 8.0 6.6 6.2 7.6 8.9 9.3 9.2 8.6 8.4 9.4 9.4 3.2 17.5 17.3 1.3 6.5 1.6 0.1 0.6 5.4 1.2 1.1 16.7 0.0 9.4 0.0 2.1 0.4 3.7 0.2 1.9 0.1 88.5 0.8 10.7 6.2 0.0 0.0 11.1 0.0 0.3 29.7 0.0 0.7 12.6 96.9 5.3 5.0 0.7 5.0 7.0 0.0 0.0 2.2 11.1 140.6 9.6 2.9 7.2 4.7 1.0 9.1 2.1 20.1 33.3 0.2 0.1 14.7 0.7 0.8 0.0 9.4 3.8 2.9 59.2 20.6 37.7 1.3 4.4 0.4 4.3 0.4 2.0 44.7 0.0 0.7 VTA1 "C6orf55, HSPC228, My012" ENSG00000009844 "Vesicle trafficking 1" Q9NP79 6 142147162-142224685 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030968, HPA030969" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA 220000 "Cluster 18: Basophils - Vesicular transport" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Vesicles, Cytosol" "HPA030968: AB_10602585, HPA030969: AB_2673679" "prognostic unfavorable (7.02e-4)" "unprognostic (1.84e-2)" "unprognostic (2.12e-3)" "unprognostic (1.17e-2)" "unprognostic (1.08e-2)" "unprognostic (2.56e-2)" "prognostic unfavorable (6.58e-6)" "unprognostic (2.83e-2)" "unprognostic (3.61e-1)" "unprognostic (5.18e-2)" "unprognostic (2.84e-2)" "unprognostic (1.16e-1)" "unprognostic (3.85e-2)" "unprognostic (1.66e-1)" "unprognostic (1.64e-1)" "unprognostic (1.96e-1)" "unprognostic (3.24e-1)" 22.2 20.9 16.6 25.7 19.0 30.6 31.6 20.2 20.3 23.2 12.5 34.9 38.2 23.4 25.4 39.1 27.3 23.0 33.9 18.9 18.9 34.5 45.4 21.5 33.4 17.4 18.1 21.0 19.3 28.3 9.9 32.1 17.8 22.5 39.9 29.2 18.2 19.6 55.7 30.7 37.0 26.3 21.1 23.1 23.5 18.3 18.2 45.4 27.6 58.3 39.1 35.8 20.3 22.2 56.5 47.5 75.8 116.8 65.3 71.4 52.3 124.7 74.0 111.6 105.8 80.9 43.0 91.2 82.1 112.6 84.6 70.2 81.5 85.1 153.4 62.3 71.7 99.2 46.2 97.0 48.2 155.6 55.2 59.4 97.7 111.8 71.7 59.8 72.4 69.7 93.7 44.5 94.5 82.1 101.8 80.7 57.0 72.1 53.8 92.1 60.8 55.8 86.4 61.5 79.0 61.5 70.1 53.3 63.7 62.9 57.8 104.4 53.0 50.0 69.6 84.7 90.8 43.5 80.9 103.8 32.7 85.5 77.8 222.4 90.0 151.9 64.3 114.5 83.5 85.6 72.8 76.0 90.9 84.8 79.8 80.4 56.0 97.5 120.3 55.9 79.0 121.5 16.6 19.0 20.2 20.3 18.9 18.9 17.4 18.1 17.8 21.1 18.2 22.2 16.7 22.4 20.3 22.5 25.8 25.2 19.2 25.5 25.6 9.7 16.5 18.3 47.8 12.8 24.5 16.5 0.0 32.7 23.9 40.2 17.6 31.5 4.5 30.7 30.4 17.5 21.6 23.1 40.1 28.0 36.4 25.4 16.8 28.0 12.6 18.1 11.4 24.7 27.9 11.8 38.7 24.7 14.2 20.9 14.3 2.2 11.8 20.0 8.8 40.3 28.0 23.9 35.0 25.6 48.7 30.1 18.3 12.4 16.4 17.2 30.0 31.6 36.6 12.6 6.6 16.8 18.4 23.6 24.9 28.8 31.0 31.7 23.8 25.3 25.9 18.8 VTI1A "MVti1, Vti1-rp2" ENSG00000151532 "Vesicle transport through interaction with t-SNAREs 1A" Q96AJ9 10 112446998-112818744 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Astrocytes: 135.2;Excitatory neurons: 244.7;Inhibitory neurons: 199.5;Late spermatids: 102.8;Microglial cells: 195.8;Oligodendrocyte precursor cells: 172.4;Oligodendrocytes: 218.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054108 Supported Supported "Golgi apparatus,Vesicles" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Vesicles" "HPA054108: AB_2682382" "unprognostic (9.81e-2)" "unprognostic (6.42e-2)" "unprognostic (4.49e-2)" "unprognostic (1.50e-1)" "unprognostic (1.66e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (6.50e-5)" "unprognostic (1.71e-1)" "unprognostic (1.59e-1)" "unprognostic (2.00e-1)" "unprognostic (1.22e-1)" "unprognostic (8.05e-2)" "prognostic favorable (7.27e-5)" "unprognostic (3.74e-2)" "unprognostic (1.98e-1)" "unprognostic (1.67e-3)" "unprognostic (2.61e-1)" 6.6 4.7 3.7 7.0 3.7 13.8 4.7 2.3 4.7 3.5 1.1 6.4 7.2 3.8 4.9 7.3 3.2 4.6 5.8 4.8 2.6 6.8 4.7 5.1 7.7 2.8 3.7 3.1 3.9 7.5 2.6 4.0 3.5 4.7 7.5 4.2 5.2 4.8 7.4 5.9 7.2 5.7 1.8 5.6 5.5 4.5 4.3 8.6 6.3 6.1 9.4 5.2 4.4 4.6 13.5 11.2 10.1 14.1 15.5 13.4 6.1 14.1 17.4 11.0 12.2 12.7 13.6 14.0 5.3 16.0 9.3 15.6 8.8 11.2 14.9 18.0 8.1 11.9 8.1 13.3 11.0 16.8 16.8 10.4 13.9 12.6 25.9 12.4 11.9 14.1 11.3 16.9 14.8 9.5 13.3 12.8 4.4 10.5 6.5 13.9 14.6 6.2 11.5 11.9 4.6 9.0 10.0 8.6 9.5 8.4 7.8 9.3 17.0 8.7 7.4 10.8 15.8 7.4 11.0 15.9 14.2 15.3 8.6 9.2 7.0 9.6 5.4 9.3 5.1 5.5 4.5 4.4 5.2 4.6 4.3 4.4 11.4 5.7 8.7 4.9 7.2 4.6 3.7 3.7 2.3 4.7 4.8 2.6 2.8 3.7 3.5 1.8 4.3 4.6 13.5 12.8 10.3 135.2 33.1 11.2 14.5 8.8 13.6 16.5 7.8 4.6 14.0 7.2 11.6 5.5 43.8 7.6 31.5 17.0 7.9 15.4 42.9 11.4 15.5 13.6 18.5 18.1 244.7 25.0 12.3 12.9 21.9 17.0 19.6 10.2 8.9 8.1 18.8 21.9 199.5 10.7 14.2 17.0 27.0 102.8 6.8 20.9 12.4 195.8 19.0 6.0 25.7 172.4 218.6 29.7 12.2 5.7 23.9 12.6 17.2 9.4 11.7 20.7 0.0 13.5 14.1 11.1 9.2 17.0 16.3 14.4 25.4 9.7 12.1 19.7 VTI1B VTI2 ENSG00000100568 "Vesicle transport through interaction with t-SNAREs 1B" Q9UEU0 14 67647085-67674820 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 493.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044121, HPA048150, HPA060118" Approved Enhanced "Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "HPA044121: AB_2678819, HPA048150: AB_2680288, HPA060118: AB_2684206" "unprognostic (2.26e-1)" "unprognostic (4.83e-2)" "unprognostic (8.09e-2)" "unprognostic (2.24e-1)" "unprognostic (3.00e-2)" "unprognostic (2.36e-3)" "unprognostic (3.25e-3)" "unprognostic (9.12e-2)" "unprognostic (1.90e-2)" "unprognostic (3.86e-1)" "unprognostic (2.60e-1)" "unprognostic (2.11e-2)" "prognostic favorable (3.53e-12)" "unprognostic (8.35e-3)" "unprognostic (1.53e-1)" "unprognostic (1.43e-1)" "unprognostic (8.02e-3)" 53.8 26.9 55.5 20.4 56.8 22.3 39.8 54.4 102.1 22.7 49.8 42.9 28.3 18.4 53.5 44.3 18.5 28.7 60.1 56.6 58.1 53.0 41.6 26.8 23.8 55.1 56.6 21.0 44.0 23.9 17.1 21.3 56.8 22.3 35.2 23.0 30.1 13.6 46.5 31.0 24.1 22.4 56.0 26.5 40.0 30.8 56.3 12.1 34.0 28.2 27.0 33.3 23.4 56.9 111.7 54.8 31.4 18.1 61.9 37.2 45.4 48.1 30.5 23.8 23.7 27.3 38.5 32.9 40.2 54.5 27.5 30.6 36.8 36.6 37.7 34.3 22.6 33.4 32.5 34.8 26.6 20.9 22.9 36.3 39.6 25.6 26.1 60.5 27.2 23.1 22.2 25.4 34.5 131.1 26.6 77.7 20.3 76.6 88.0 31.8 35.6 12.2 35.1 65.0 17.4 35.5 33.8 45.5 71.4 23.7 41.9 58.0 38.5 62.6 93.8 51.4 45.6 23.8 27.8 53.2 52.9 38.9 29.0 88.8 61.5 143.8 49.4 80.4 42.4 49.0 43.1 51.1 59.6 43.0 40.5 50.3 27.2 56.4 70.2 38.6 60.2 58.3 55.5 56.8 54.4 102.1 56.6 58.1 55.1 56.6 56.8 56.0 56.3 56.9 47.6 25.6 35.0 13.1 48.7 42.3 61.4 91.7 33.0 23.2 82.2 65.4 30.5 67.2 64.4 66.2 22.9 107.4 47.5 138.2 217.2 109.1 141.7 58.5 43.2 51.5 46.6 102.7 15.8 131.4 167.9 51.6 40.8 49.5 64.0 43.6 73.9 95.3 131.4 15.2 18.2 96.0 50.8 99.8 49.2 493.5 41.7 80.9 71.2 11.2 121.6 65.4 78.2 13.6 17.1 130.7 119.4 39.9 51.0 120.5 165.4 268.6 55.3 44.8 19.7 36.5 58.2 104.5 57.2 58.2 52.8 125.9 46.8 35.5 91.9 124.6 VTN VN ENSG00000109072 Vitronectin P04004 17 28367284-28373091 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 61 "liver: 6039.5" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 5507.4" "Cancer enriched" "Detected in many" 85 "liver cancer: 2216.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 15 "CACO-2: 1748.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016695, CAB016765, HPA060933, HPA068011" Supported Supported "Endoplasmic reticulum,Vesicles" "Secreted to blood" NA NA 606000000000 33000000000 "Cluster 62: Liver - Hemostasis" "Cluster 39: CACO-2 - Unknown function" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum, Vesicles" "CAB016695: AB_1624536, CAB016765: , HPA060933: AB_2684389, HPA068011: " "unprognostic (1.19e-1)" "unprognostic (2.12e-1)" "unprognostic (2.29e-2)" "unprognostic (6.13e-2)" "unprognostic (9.74e-2)" "unprognostic (8.42e-2)" "prognostic favorable (3.74e-4)" "unprognostic (6.20e-2)" "unprognostic (3.97e-1)" "unprognostic (8.95e-2)" "unprognostic (3.24e-3)" "unprognostic (1.01e-2)" "prognostic unfavorable (4.10e-11)" "unprognostic (8.82e-3)" "unprognostic (2.27e-1)" "unprognostic (4.86e-3)" "unprognostic (7.09e-2)" 6.2 98.9 2.4 2.5 2.7 0.3 0.9 5.4 3.7 1.0 0.4 0.9 4.6 1.4 0.9 0.5 2.2 61.2 53.1 2.5 2.8 3.6 6039.5 1.8 4.3 2.1 5.3 1.9 17.7 0.1 3.0 40.6 2.3 1.2 0.3 47.4 0.6 4.3 0.4 0.8 1.3 2.7 1.5 2.9 5.1 10.0 2.2 0.1 0.8 0.5 0.4 4.2 0.7 2.4 0.0 28.4 0.7 0.4 0.2 0.3 7.3 1.8 0.8 0.9 0.9 1748.9 0.1 1.2 0.2 0.2 0.2 0.7 0.0 0.0 0.1 0.2 0.2 1.2 1.1 86.7 2.5 6.1 0.5 0.4 0.0 0.6 0.0 3.9 0.1 0.0 1.6 0.3 0.2 0.7 0.2 0.0 0.8 0.4 0.1 0.4 3.5 0.1 0.3 0.0 1.0 1.4 115.6 8.0 0.2 4.3 0.3 0.0 1.0 0.4 0.3 0.1 0.2 1.0 0.5 1.4 0.5 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 2.4 2.7 5.4 3.7 2.5 2.8 2.1 5.3 2.3 1.5 2.2 2.4 0.1 0.0 1.1 2.0 21.5 0.0 0.0 0.0 0.0 13.0 0.1 0.1 18.1 1162.4 0.0 0.0 77.2 3.7 0.0 0.0 3.9 16.8 0.0 0.0 1.2 7.3 0.0 131.0 0.9 19.7 2.8 48.1 0.0 0.0 0.0 1.8 120.3 5507.4 4.7 38.7 1.0 0.1 0.0 160.3 0.3 0.2 0.0 0.3 0.0 0.0 20.1 6.9 0.0 1.0 0.5 23.5 1.2 1.5 0.0 0.0 0.1 9.5 0.0 38.3 0.0 0.4 1.5 4.2 0.6 0.0 0.0 9.6 9.0 0.7 0.0 0.0 VWA8 KIAA0564 ENSG00000102763 "Von Willebrand factor A domain containing 8" A3KMH1 13 41566835-41961120 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 161.9;Excitatory neurons: 183.9;Inhibitory neurons: 252.6;Oligodendrocyte precursor cells: 151.3;Oligodendrocytes: 146.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039075, HPA045478" Uncertain Approved "Vesicles,Lipid droplets" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Lipid droplets" "HPA039075: AB_2676334, HPA045478: AB_2679341" "unprognostic (9.93e-2)" "unprognostic (4.12e-2)" "unprognostic (2.11e-1)" "unprognostic (2.57e-3)" "unprognostic (4.14e-2)" "unprognostic (1.50e-2)" "prognostic favorable (8.56e-4)" "unprognostic (1.03e-1)" "unprognostic (3.01e-2)" "unprognostic (3.31e-3)" "unprognostic (5.35e-2)" "unprognostic (2.44e-1)" "prognostic favorable (6.38e-14)" "unprognostic (1.84e-2)" "unprognostic (3.07e-2)" "unprognostic (2.12e-1)" "unprognostic (3.26e-1)" 8.0 7.8 5.1 3.7 6.8 5.7 8.7 9.5 5.6 9.2 14.3 6.8 7.1 7.2 5.5 5.7 6.4 5.3 13.7 2.9 5.0 17.6 21.6 4.9 4.5 5.5 6.4 6.3 7.3 14.6 3.8 5.0 6.2 6.1 7.5 15.1 7.7 5.8 29.3 4.1 5.4 6.0 4.0 3.7 6.6 4.1 7.9 7.7 7.1 35.1 4.4 6.2 3.8 5.1 5.2 7.6 7.6 10.5 7.0 10.2 7.1 8.2 12.0 7.3 5.8 10.0 8.2 13.8 5.4 7.2 5.9 18.3 7.1 20.0 9.1 15.6 12.3 13.1 7.0 12.7 7.5 17.3 1.7 12.0 12.2 7.0 16.7 9.9 7.4 10.8 12.7 9.6 6.5 7.0 9.8 8.9 11.4 13.6 7.0 0.1 4.8 14.5 19.7 18.8 4.7 10.0 10.2 15.9 11.4 8.3 6.6 13.2 6.6 5.5 5.8 7.1 7.8 9.7 9.9 21.4 6.1 8.2 7.3 0.6 0.4 0.0 1.1 0.4 1.6 0.7 0.6 1.0 0.9 1.0 0.8 1.2 0.2 1.6 0.6 0.5 0.4 0.8 5.1 6.8 9.5 5.6 2.9 5.0 5.5 6.4 6.2 4.0 7.9 5.1 7.5 16.0 2.6 161.9 9.2 4.0 16.5 8.2 9.6 10.7 13.1 5.7 45.5 11.5 10.4 5.5 35.5 7.6 7.3 7.5 1.9 3.7 35.4 10.1 7.6 5.3 3.0 12.0 183.9 1.6 2.1 6.2 15.8 14.4 0.0 5.8 2.2 16.5 3.9 3.3 252.6 7.8 4.1 3.8 4.0 14.2 5.9 11.5 5.4 69.3 4.1 4.9 4.1 151.3 146.1 4.0 9.3 5.3 18.2 16.0 9.4 8.2 6.7 42.6 0.0 7.6 8.9 5.5 4.8 12.5 2.8 2.9 10.4 8.5 9.4 11.9 VWCE "FLJ32009, URG11, VWC1" ENSG00000167992 "Von Willebrand factor C and EGF domains" Q96DN2 11 61258286-61295316 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 14.3;ovary: 7.9" "Cell type enhanced" "Detected in many" "Astrocytes: 19.2;Cone photoreceptor cells: 29.2;Hepatocytes: 16.4;Rod photoreceptor cells: 21.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 7.2;Hep G2: 26.3;HSkMC: 13.4;REH: 14.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA040401, HPA043921" Uncertain Supported Nucleoplasm,Vesicles,Cytosol "Secreted - unknown location" NA NA 2200000 "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "Vesicles, Cytosol" "HPA040401: AB_2676963, HPA043921: AB_2678731" "unprognostic (3.09e-2)" "unprognostic (1.10e-1)" "unprognostic (3.58e-2)" "unprognostic (1.15e-1)" "unprognostic (3.96e-3)" "unprognostic (9.27e-4)" "unprognostic (1.21e-2)" "unprognostic (4.01e-4)" "unprognostic (3.04e-2)" "unprognostic (3.42e-2)" "unprognostic (6.58e-4)" "unprognostic (7.20e-2)" "unprognostic (3.01e-1)" "unprognostic (1.25e-2)" "unprognostic (1.92e-1)" "unprognostic (2.34e-1)" "unprognostic (2.30e-1)" 2.8 1.1 0.6 0.1 0.9 1.6 1.5 0.3 1.6 2.9 0.0 0.6 0.3 1.3 0.6 0.9 3.5 0.6 0.8 0.7 0.7 0.5 14.3 0.3 0.2 0.5 1.2 7.9 0.3 0.1 0.6 2.4 0.4 1.0 0.4 0.8 0.9 0.5 0.7 0.7 0.4 0.4 0.0 0.4 0.4 1.8 0.5 2.5 0.8 0.4 0.1 0.6 1.2 0.2 0.0 0.1 1.5 0.2 0.2 1.8 0.6 0.2 2.0 0.0 0.3 7.2 0.0 0.5 0.0 0.4 0.1 0.0 2.3 0.0 0.1 0.4 0.0 0.8 0.0 26.3 1.2 0.0 0.3 13.4 0.6 0.7 0.0 0.1 2.3 3.3 0.2 0.3 0.3 0.1 5.5 0.0 2.2 0.0 0.0 14.0 0.2 0.0 0.1 0.1 0.6 1.0 0.0 0.1 0.7 2.4 0.9 0.0 0.8 0.3 0.3 0.5 0.2 0.2 0.6 1.2 0.9 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.9 0.3 1.6 0.7 0.7 0.5 1.2 0.4 0.0 0.5 0.2 2.1 3.2 1.7 19.2 0.3 1.8 1.8 3.8 3.4 3.6 1.7 0.5 1.0 1.5 2.3 0.0 29.2 1.0 0.5 0.2 0.0 0.1 0.5 2.9 1.0 5.5 1.8 6.1 7.5 0.5 5.0 2.6 0.0 1.8 3.8 6.5 2.5 16.4 1.2 0.0 5.8 0.1 2.0 3.5 2.4 0.8 6.8 2.6 1.8 2.8 2.3 2.3 1.0 2.5 1.4 0.0 0.0 1.9 0.4 1.1 0.1 0.3 5.4 21.1 0.0 0.9 1.1 1.1 3.4 1.3 2.3 4.4 0.9 7.7 0.3 0.7 WASH6P "CXYorf1, FAM39A" ENSG00000182484 "WASP family homolog 6, pseudogene" X 156020826-156025710 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 6 "granulocytes: 225.3" "Cancer enhanced" "Detected in all" "urothelial cancer: 10.6" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" HPA002689 Uncertain Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 60: Granulocytes - Receptor signaling" Vesicles "HPA002689: AB_1078803" "unprognostic (2.01e-1)" "unprognostic (3.42e-2)" "unprognostic (1.06e-1)" "prognostic unfavorable (7.56e-4)" "unprognostic (4.69e-2)" "unprognostic (4.20e-2)" "unprognostic (1.53e-2)" "unprognostic (2.23e-2)" "unprognostic (1.19e-1)" "unprognostic (8.93e-2)" "unprognostic (1.33e-3)" "unprognostic (3.94e-2)" "unprognostic (8.18e-2)" "unprognostic (2.11e-1)" "unprognostic (2.15e-1)" "unprognostic (1.45e-1)" "unprognostic (5.86e-3)" 1.0 1.3 1.0 1.7 1.0 3.5 1.0 1.2 1.6 0.5 1.3 1.0 2.6 1.6 2.7 0.4 1.1 0.8 1.2 1.2 1.0 2.3 0.7 1.2 1.8 1.8 1.2 1.7 4.1 0.7 1.2 1.5 1.1 0.7 3.6 0.9 1.2 6.5 3.1 2.2 0.6 0.8 2.9 1.7 2.3 1.6 1.1 1.2 0.6 0.9 0.7 2.5 9.6 1.5 1.6 5.0 0.7 0.0 5.9 2.5 0.4 0.8 1.5 0.4 5.2 3.1 1.7 1.4 4.0 7.3 1.2 2.0 0.7 0.7 1.7 4.7 0.6 1.3 0.0 1.8 3.7 0.2 0.9 1.4 2.0 0.5 1.2 0.9 6.2 4.6 0.0 1.2 7.9 4.1 2.3 4.2 0.9 7.0 3.0 2.0 0.3 0.4 4.2 6.3 3.1 4.7 5.7 1.3 6.6 5.8 3.1 3.5 3.4 3.3 3.9 8.0 9.8 1.8 0.8 3.1 3.9 0.4 0.2 0.0 0.3 0.2 0.3 0.4 0.0 0.3 0.2 0.3 0.1 0.2 0.1 0.8 1.1 0.2 0.4 0.3 1.0 1.0 1.2 1.6 1.2 1.0 1.8 1.2 1.5 0.8 1.6 2.5 0.0 35.3 23.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.0 0.2 5.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 225.3 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 5.3 0.0 WASHC1 "FAM39E, FLJ00038, WASH1" ENSG00000181404 "WASH complex subunit 1" A8K0Z3 9 14475-73865 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 60.7;Distal tubular cells: 50.9;Proximal tubular cells: 47.5;Syncytiotrophoblasts: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA002689 Uncertain Supported Vesicles NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA002689: AB_1078803" "unprognostic (9.43e-2)" "unprognostic (1.62e-2)" "unprognostic (3.16e-2)" "unprognostic (1.30e-1)" "unprognostic (1.43e-1)" "unprognostic (2.33e-2)" "unprognostic (3.22e-3)" "unprognostic (2.06e-2)" "unprognostic (5.00e-1)" "unprognostic (5.40e-3)" "unprognostic (3.37e-3)" "unprognostic (6.95e-2)" "unprognostic (3.90e-2)" "unprognostic (1.88e-1)" "unprognostic (3.38e-1)" "unprognostic (2.31e-2)" "unprognostic (1.02e-1)" 15.7 18.1 13.2 7.1 14.2 16.3 17.6 13.2 15.1 24.5 16.5 19.6 10.2 20.3 21.9 19.2 24.1 9.0 17.9 13.3 13.5 25.9 20.9 17.1 13.4 14.4 13.8 23.0 21.9 5.2 21.2 6.6 14.3 27.0 4.7 15.9 17.6 13.5 22.8 26.1 21.9 15.3 13.4 29.0 18.3 24.1 14.5 8.6 22.1 6.8 6.0 19.7 20.5 14.9 13.5 8.5 5.0 10.3 8.5 5.7 12.4 11.7 11.4 6.9 5.5 8.4 8.3 5.7 6.6 4.8 6.2 16.7 7.4 5.7 2.5 5.9 14.4 5.5 7.0 8.6 4.7 11.3 10.0 4.3 4.2 3.5 4.7 17.3 2.1 5.0 12.6 21.0 2.2 4.0 11.6 9.4 9.2 9.1 10.5 7.9 4.3 7.2 5.1 9.8 5.6 14.9 6.8 14.3 8.6 6.2 8.6 10.5 8.0 9.2 6.7 4.0 10.3 9.4 7.9 4.5 8.6 12.0 8.6 1.2 2.5 2.2 1.9 2.7 1.5 1.3 1.5 1.6 2.3 1.2 1.6 1.3 1.4 2.1 4.0 2.1 1.8 1.5 13.2 14.2 13.2 15.1 13.3 13.5 14.4 13.8 14.3 13.4 14.5 14.9 34.5 22.4 22.5 0.0 10.5 0.0 0.0 0.0 0.0 0.0 29.0 28.3 0.0 0.0 7.4 60.7 0.0 37.4 21.5 0.0 50.9 13.7 0.0 24.7 28.6 7.5 0.0 0.0 0.0 15.8 26.1 10.8 0.0 22.9 16.4 27.3 0.0 0.0 26.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.5 0.0 0.0 4.6 0.0 0.0 0.0 0.0 13.1 0.0 0.0 6.7 0.0 0.0 47.5 8.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 42.8 11.4 14.3 0.0 0.0 WASHC2A "bA56A21.1, bA98I6.1, FAM21A, FAM21B, FLJ10824" ENSG00000099290 "WASH complex subunit 2A" Q641Q2 10 50067888-50133509 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Alveolar cells type 2: 28.5;Endometrial ciliated cells: 45.7;Respiratory ciliated cells: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA047844, HPA060975, HPA061022" Supported Supported Nucleoli,Vesicles,Cytosol NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 7: Non-specific - Mitochondria" Vesicles "Nucleoli, Cytosol" "HPA047844: AB_2680177, HPA060975: AB_2684401, HPA061022: AB_2732656" "unprognostic (2.46e-1)" "unprognostic (1.11e-3)" "unprognostic (8.82e-2)" "unprognostic (3.28e-1)" "unprognostic (2.75e-1)" "unprognostic (6.51e-3)" "prognostic unfavorable (6.75e-5)" "unprognostic (4.60e-2)" "unprognostic (2.85e-2)" "unprognostic (2.37e-2)" "unprognostic (9.04e-2)" "unprognostic (2.73e-2)" "unprognostic (1.18e-1)" "unprognostic (2.57e-1)" "unprognostic (2.95e-1)" "unprognostic (1.85e-2)" "unprognostic (4.40e-2)" 25.3 25.9 19.9 22.1 20.7 37.5 24.0 23.4 24.8 24.7 18.3 28.9 25.2 22.5 19.2 20.2 19.7 18.0 58.6 19.9 19.9 22.9 15.5 26.0 28.8 21.1 21.2 26.7 17.7 23.3 21.5 22.9 21.1 20.6 28.9 19.9 21.9 20.0 22.3 25.7 28.9 21.2 18.6 26.6 21.5 12.5 22.6 24.2 23.3 15.6 26.9 23.8 22.1 23.9 26.1 12.5 21.1 24.3 83.2 46.0 16.9 29.8 64.0 43.7 46.6 28.8 37.8 22.5 18.1 44.8 41.3 28.0 31.2 25.3 43.2 22.2 22.0 15.9 25.6 29.7 58.6 28.0 27.2 47.8 31.2 47.6 30.5 46.2 33.1 19.2 26.6 22.2 53.9 19.1 15.5 48.0 17.1 16.7 58.4 23.1 30.1 13.7 30.5 29.3 7.3 22.4 27.8 25.9 40.9 30.9 31.6 19.2 49.4 22.0 18.5 62.7 25.0 23.4 48.3 19.1 48.9 51.4 9.0 1.0 9.1 9.9 9.1 11.6 10.1 5.1 8.0 8.8 7.3 4.9 7.7 6.0 4.1 8.2 6.9 4.6 9.2 7.9 19.9 20.7 23.4 24.8 19.9 19.9 21.1 21.2 21.1 18.6 22.6 23.9 16.2 38.5 28.5 0.0 3.3 0.0 0.0 0.0 0.0 0.0 10.6 11.0 0.0 0.0 22.9 14.7 0.0 7.4 10.0 0.0 0.0 16.7 0.0 45.7 19.9 7.9 0.0 0.0 0.0 15.6 6.9 8.9 0.0 20.3 15.2 13.5 0.0 0.0 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.2 0.0 0.0 5.7 0.0 0.0 0.0 0.0 15.1 0.0 0.0 2.6 0.0 0.0 11.7 41.5 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 7.7 7.8 9.4 0.0 0.0 WASHC2C "Em:AC012044.3, FAM21C, KIAA0592" ENSG00000172661 "WASH complex subunit 2C" Q9Y4E1 10 45727200-45792964 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 35.3;Alveolar cells type 2: 35.2;Collecting duct cells: 23.9;granulocytes: 30.3;Respiratory ciliated cells: 24.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA047844, HPA060975, HPA061022" Supported Supported Nucleoli,Vesicles,Cytosol NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" Vesicles "Nucleoli, Cytosol" "HPA047844: AB_2680177, HPA060975: AB_2684401, HPA061022: AB_2732656" "unprognostic (7.50e-2)" "unprognostic (2.32e-2)" "unprognostic (1.13e-1)" "unprognostic (1.06e-1)" "unprognostic (4.51e-2)" "unprognostic (5.98e-3)" "prognostic unfavorable (1.35e-5)" "prognostic favorable (4.69e-4)" "unprognostic (1.26e-1)" "unprognostic (5.02e-2)" "unprognostic (1.00e-3)" "unprognostic (1.51e-1)" "unprognostic (2.24e-1)" "unprognostic (1.48e-1)" "unprognostic (1.09e-1)" "unprognostic (1.73e-1)" "unprognostic (2.00e-2)" 19.4 15.7 10.9 17.3 11.8 42.5 17.5 14.8 14.9 19.1 13.5 20.3 15.2 16.8 12.4 13.5 14.9 16.5 22.0 11.3 11.4 18.0 15.9 17.7 20.2 12.5 12.2 21.6 11.6 21.4 13.9 13.7 12.7 15.6 22.0 14.2 15.3 14.6 17.1 17.6 19.7 19.0 9.6 19.3 15.0 12.9 14.1 21.2 17.1 9.8 18.7 17.7 14.6 14.0 24.5 25.9 20.7 23.5 52.1 45.8 12.4 28.4 45.8 32.4 30.8 16.0 23.3 20.1 18.8 41.7 30.8 21.6 23.2 13.0 32.6 18.9 19.2 20.9 32.3 12.3 55.0 21.4 24.6 43.4 30.4 35.4 26.1 31.6 33.7 16.5 33.9 15.7 40.1 12.8 14.0 35.9 14.8 14.7 3.9 17.4 30.5 10.5 23.8 38.2 10.0 22.3 32.8 16.1 39.4 21.0 22.1 20.6 58.1 16.8 18.0 44.7 19.1 21.5 36.3 19.6 23.5 49.4 9.2 14.1 17.1 11.7 12.2 17.9 11.8 9.9 10.1 12.7 11.7 9.2 10.0 8.9 16.8 12.5 22.8 8.1 10.4 13.3 10.9 11.8 14.8 14.9 11.3 11.4 12.5 12.2 12.7 9.6 14.1 14.0 16.2 35.3 35.2 0.0 3.0 0.0 0.0 0.0 0.0 0.0 11.3 8.8 0.0 0.0 11.8 23.9 0.0 6.8 11.8 0.0 3.9 13.5 0.0 11.3 17.9 6.1 0.0 0.0 0.0 14.0 6.4 7.9 0.0 13.9 30.3 13.7 0.0 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 10.3 0.0 0.0 0.0 0.0 11.9 0.0 0.0 3.8 0.0 0.0 12.8 24.8 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 7.8 7.0 12.1 0.0 0.0 WASHC3 "CCDC53, CGI-116" ENSG00000120860 "WASH complex subunit 3" Q9Y3C0 12 102012840-102062149 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 125.2;Hofbauer cells: 73.1;Proximal tubular cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038339 Uncertain Approved Vesicles NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 43: Testis - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA038339: AB_2675966" "unprognostic (4.25e-2)" "unprognostic (1.61e-2)" "unprognostic (2.28e-1)" "unprognostic (3.45e-3)" "unprognostic (1.21e-2)" "unprognostic (2.42e-1)" "unprognostic (2.11e-1)" "unprognostic (1.12e-1)" "unprognostic (1.04e-1)" "unprognostic (9.63e-2)" "unprognostic (7.54e-2)" "unprognostic (4.98e-2)" "unprognostic (7.81e-2)" "unprognostic (7.41e-2)" "unprognostic (1.74e-1)" "unprognostic (1.08e-1)" "unprognostic (1.08e-1)" 27.3 32.2 41.3 14.2 41.9 13.2 24.7 42.8 57.2 26.4 38.3 33.7 13.6 27.5 35.7 28.4 18.0 17.7 35.0 42.8 44.9 41.6 41.1 20.6 22.8 44.6 43.9 20.3 17.4 37.8 33.4 20.0 45.2 26.1 20.7 25.3 19.8 34.9 34.5 20.1 20.5 29.3 43.4 22.7 27.3 98.1 43.5 31.2 25.7 42.2 26.2 28.8 23.4 44.2 17.1 23.3 20.1 12.6 75.2 90.9 18.9 23.3 48.0 33.6 37.3 18.8 16.0 18.0 16.4 52.9 34.2 32.1 21.4 57.0 44.5 41.8 12.9 25.3 15.9 29.5 67.0 22.4 13.9 55.9 72.4 42.1 42.2 92.1 46.3 43.5 15.3 19.6 88.4 23.1 23.6 39.9 6.1 32.7 41.0 13.6 30.4 27.2 59.4 27.7 19.6 10.8 32.6 22.9 50.2 36.5 29.1 12.8 25.5 41.5 9.9 24.7 16.3 49.5 32.7 22.7 59.0 15.6 17.8 125.7 41.3 95.3 37.5 66.6 45.4 61.9 56.3 50.7 56.1 49.4 41.2 49.4 18.2 59.9 70.9 54.9 118.5 52.8 41.3 41.9 42.8 57.2 42.8 44.9 44.6 43.9 45.2 43.4 43.5 44.2 55.4 28.9 41.5 0.0 18.5 0.0 0.0 0.0 0.0 0.0 36.4 55.4 0.0 0.0 14.2 33.1 0.0 60.3 28.4 0.0 125.2 47.9 0.0 40.5 49.2 15.0 0.0 0.0 0.0 38.8 48.5 24.8 0.0 27.4 40.4 36.1 0.0 0.0 73.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.0 0.0 0.0 46.5 0.0 0.0 0.0 0.0 35.5 0.0 0.0 5.4 0.0 0.0 98.9 22.6 0.0 0.0 0.0 22.8 0.0 0.0 0.0 0.0 39.4 18.8 60.9 0.0 0.0 WBP4 "FBP21, MGC117310" ENSG00000120688 "WW domain binding protein 4" O75554 13 41061509-41084006 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038965, HPA058738" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 80: Striated muscle - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Vesicles, Plasma membrane" "HPA038965: AB_10672836, HPA058738: AB_2683803" "unprognostic (2.56e-1)" "unprognostic (3.69e-3)" "unprognostic (1.75e-1)" "unprognostic (1.99e-2)" "unprognostic (9.30e-2)" "unprognostic (1.76e-3)" "unprognostic (1.54e-2)" "unprognostic (2.13e-2)" "unprognostic (1.34e-2)" "unprognostic (2.05e-2)" "unprognostic (3.71e-3)" "unprognostic (2.97e-1)" "unprognostic (2.66e-2)" "unprognostic (8.52e-2)" "unprognostic (7.65e-3)" "prognostic favorable (2.89e-4)" "unprognostic (2.52e-1)" 17.5 16.0 16.1 9.8 16.8 15.6 13.4 16.5 23.9 12.0 13.2 13.2 11.2 18.5 16.0 11.2 11.1 9.3 23.1 16.1 18.1 12.3 16.3 10.4 11.8 16.3 16.6 13.2 8.7 12.4 8.2 11.5 16.4 14.0 9.1 16.5 8.1 14.7 41.0 11.3 11.5 14.8 15.7 9.8 9.3 12.2 16.5 14.7 11.2 29.8 11.6 11.3 11.0 18.6 15.0 9.8 26.7 17.3 17.1 25.9 16.2 33.3 23.4 25.9 19.7 15.5 15.7 21.4 13.0 23.6 31.2 20.6 10.2 16.7 33.0 22.3 14.3 30.2 10.0 16.0 26.3 19.1 18.8 21.3 25.0 18.8 26.5 21.1 22.0 20.3 16.4 9.1 27.5 12.6 27.3 20.6 16.3 23.2 8.0 25.3 16.5 8.4 23.6 14.6 6.1 14.7 10.6 11.3 16.1 21.5 9.4 29.3 19.3 16.0 14.7 22.2 19.5 6.0 7.0 14.7 19.7 13.7 22.2 19.2 13.0 12.4 10.6 12.0 9.7 14.2 13.6 11.5 11.0 12.6 14.4 14.3 27.3 12.5 21.8 18.5 14.4 6.1 16.1 16.8 16.5 23.9 16.1 18.1 16.3 16.6 16.4 15.7 16.5 18.6 42.4 51.3 29.3 21.2 23.9 54.4 60.3 54.8 33.0 46.8 33.5 37.5 110.0 40.0 32.5 25.8 33.3 55.6 23.0 32.3 76.3 52.3 11.9 32.9 58.4 46.9 37.8 111.7 17.0 42.0 61.1 52.2 15.8 44.5 45.7 27.5 38.2 63.1 40.9 45.4 16.6 28.1 18.3 26.7 47.1 9.7 47.8 33.0 32.0 10.3 60.4 63.8 28.8 17.1 33.3 50.3 33.2 52.6 16.8 60.9 33.8 70.6 23.6 49.2 26.3 55.3 66.7 87.5 103.9 29.7 44.9 49.9 22.3 31.9 27.6 40.9 WDFY1 "FENS-1, KIAA1435, WDF1, ZFYVE17" ENSG00000085449 "WD repeat and FYVE domain containing 1" Q8IWB7 2 223855716-223945357 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050603, HPA079597" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Vesicles" "HPA050603: AB_2681188, HPA079597: " "unprognostic (2.49e-1)" "unprognostic (1.24e-1)" "unprognostic (2.94e-1)" "unprognostic (7.62e-2)" "unprognostic (8.24e-2)" "unprognostic (5.31e-2)" "unprognostic (2.63e-2)" "unprognostic (7.10e-2)" "unprognostic (1.26e-1)" "unprognostic (2.29e-2)" "unprognostic (1.23e-3)" "unprognostic (1.36e-1)" "unprognostic (3.81e-3)" "unprognostic (3.94e-1)" "unprognostic (2.98e-1)" "unprognostic (3.04e-1)" "unprognostic (7.55e-2)" 18.6 13.2 9.3 18.0 9.5 48.5 14.4 9.3 12.0 20.5 11.2 20.4 15.6 22.6 19.8 14.4 20.5 17.5 11.7 9.2 10.7 14.8 18.0 18.4 23.3 11.0 10.2 20.2 14.1 19.8 8.7 27.4 11.4 16.2 20.1 15.9 13.5 12.8 11.4 13.5 15.9 19.6 9.7 21.2 19.8 10.9 10.5 15.9 22.1 12.6 18.9 17.9 13.7 11.1 27.9 19.3 34.9 27.2 46.4 44.0 43.7 34.7 48.3 37.5 30.4 81.4 25.0 7.7 30.8 60.6 47.3 19.2 18.7 52.3 40.4 15.6 15.8 19.2 31.9 59.2 36.4 15.2 15.8 39.0 37.9 46.3 71.0 62.4 63.9 16.2 34.3 23.4 44.4 26.8 6.5 11.1 34.5 20.7 16.6 25.3 44.8 8.6 28.4 47.7 29.6 15.7 20.7 19.2 90.9 41.6 12.5 38.1 70.9 74.9 25.7 13.5 18.0 28.8 4.6 21.4 36.3 32.9 26.2 4.4 21.5 8.1 13.7 29.0 16.6 14.1 9.7 13.5 14.8 11.7 10.0 9.5 10.3 24.0 25.7 3.0 9.7 17.6 9.3 9.5 9.3 12.0 9.2 10.7 11.0 10.2 11.4 9.7 10.5 11.1 40.0 16.0 9.3 22.5 22.0 12.5 14.5 19.9 17.1 14.0 11.8 7.6 7.7 12.8 24.4 16.5 8.4 22.6 25.5 36.4 9.8 12.9 0.8 23.2 30.7 34.1 10.3 11.2 28.7 17.2 11.2 21.4 29.6 36.5 17.7 12.5 16.8 25.7 17.9 28.6 28.1 15.2 8.2 26.3 17.2 2.4 14.6 24.4 35.6 27.2 25.6 13.9 24.7 33.7 39.8 18.0 24.4 23.7 21.8 16.6 16.0 14.4 29.9 10.9 6.6 13.1 26.7 3.8 8.8 24.4 15.5 19.0 21.1 15.0 21.8 28.7 WDFY2 ZFYVE22 ENSG00000139668 "WD repeat and FYVE domain containing 2" Q96P53 13 51584455-51767709 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 301.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050094 Supported Vesicles NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" Vesicles "HPA050094: " "unprognostic (2.95e-1)" "unprognostic (1.78e-1)" "unprognostic (2.09e-2)" "unprognostic (2.95e-3)" "unprognostic (1.59e-1)" "unprognostic (2.41e-1)" "unprognostic (1.39e-2)" "unprognostic (9.58e-2)" "unprognostic (2.28e-1)" "unprognostic (2.59e-2)" "unprognostic (3.87e-2)" "unprognostic (1.14e-1)" "unprognostic (7.49e-4)" "unprognostic (1.47e-1)" "unprognostic (7.04e-2)" "unprognostic (6.36e-2)" "unprognostic (2.48e-1)" 6.7 11.2 8.9 4.5 12.1 15.0 7.6 9.0 8.8 8.4 4.8 3.9 1.9 5.1 5.5 9.5 6.5 2.9 3.8 8.9 10.4 4.5 6.4 5.4 4.7 11.5 9.9 8.1 17.5 15.0 5.2 5.4 12.4 5.1 2.3 6.0 5.6 4.9 1.6 17.7 4.3 3.6 10.0 7.5 6.5 6.5 10.2 4.4 5.9 3.0 5.1 4.3 8.6 15.4 1.4 2.6 11.3 4.6 5.4 11.2 3.6 11.0 7.0 5.6 4.4 1.7 1.5 4.5 1.0 7.6 3.6 5.0 6.3 19.7 10.6 3.7 3.5 9.6 3.8 13.6 4.3 6.5 4.4 9.1 9.3 12.5 14.2 9.1 2.5 4.8 2.7 2.3 9.3 3.1 4.5 14.8 13.4 3.2 3.7 5.9 4.5 3.0 7.2 3.8 3.1 7.5 3.3 4.9 5.0 9.3 2.3 15.5 9.4 10.6 2.0 5.2 7.8 1.5 2.6 3.2 12.1 6.6 13.3 6.1 7.8 4.0 2.2 8.6 3.1 3.8 2.4 1.9 13.0 4.2 2.1 2.7 5.2 4.0 9.5 11.9 3.5 3.5 8.9 12.1 9.0 8.8 8.9 10.4 11.5 9.9 12.4 10.0 10.2 15.4 16.3 16.0 21.9 118.2 36.9 23.3 20.0 10.2 45.5 35.2 25.7 24.0 7.1 8.6 17.5 29.5 127.2 28.5 41.2 7.0 27.4 19.8 46.3 19.3 23.6 13.0 13.8 17.1 47.1 23.5 33.7 20.7 14.8 20.2 29.7 35.3 27.1 18.1 28.1 37.0 47.1 9.2 8.2 63.8 30.8 19.9 39.4 41.3 12.4 96.5 45.9 26.4 16.5 106.6 301.8 15.0 4.5 21.8 17.1 12.2 9.2 6.4 14.9 52.5 26.3 45.1 27.1 32.3 16.5 46.4 27.1 14.0 27.3 41.7 10.0 16.2 WDR24 "C16orf21, DKFZp434F054, JFP7" ENSG00000127580 "WD repeat domain 24" Q96S15 16 684622-690444 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 48.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039506 Approved Supported Vesicles,Cytosol NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 71: Testis - DNA repair" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 31: Spermatids - Spermatogenesis" Vesicles Cytosol "HPA039506: AB_10795148" "unprognostic (9.07e-2)" "unprognostic (2.67e-3)" "unprognostic (6.67e-2)" "unprognostic (1.48e-1)" "unprognostic (1.67e-1)" "unprognostic (8.15e-2)" "unprognostic (7.05e-2)" "unprognostic (4.35e-2)" "unprognostic (1.75e-1)" "unprognostic (5.09e-3)" "unprognostic (2.29e-3)" "unprognostic (2.05e-1)" "prognostic favorable (3.75e-6)" "unprognostic (5.38e-2)" "unprognostic (3.16e-1)" "unprognostic (1.52e-1)" "unprognostic (2.82e-2)" 6.1 9.1 3.9 4.0 3.6 3.9 6.2 5.0 6.9 7.5 4.1 7.1 4.8 7.9 1.0 7.1 7.5 2.8 7.9 3.8 3.0 7.5 11.2 6.0 4.8 4.2 4.0 9.2 7.2 5.8 9.4 3.2 3.5 8.5 1.1 1.8 6.9 3.0 11.7 8.5 7.1 2.0 3.2 9.2 7.8 14.2 3.9 4.3 8.7 4.1 2.4 7.5 6.6 3.7 6.1 14.0 6.2 8.6 5.9 4.2 10.9 7.5 6.7 9.2 8.0 15.3 8.8 9.4 12.8 3.4 2.3 9.4 6.1 7.4 2.0 15.9 19.0 6.4 19.8 5.8 9.4 7.9 9.6 7.4 4.9 6.6 5.5 4.8 5.0 9.0 12.7 10.3 3.4 22.2 14.0 5.8 9.7 3.1 10.6 20.4 5.1 17.6 3.0 4.2 15.1 6.9 8.5 14.3 8.7 2.8 13.2 7.8 7.3 6.6 6.8 7.4 7.3 21.9 21.5 15.3 4.3 7.8 9.4 4.3 5.1 2.8 6.6 3.0 5.4 4.3 4.2 4.9 5.1 3.7 4.9 4.8 1.2 3.0 7.8 4.1 6.1 5.0 3.9 3.6 5.0 6.9 3.8 3.0 4.2 4.0 3.5 3.2 3.9 3.7 2.9 6.4 6.2 2.3 4.2 1.1 2.6 4.7 4.0 5.1 5.2 4.4 5.0 1.5 5.0 7.3 2.1 7.4 2.9 6.0 7.9 4.9 17.1 12.2 2.9 3.1 10.1 5.2 2.0 5.6 4.4 3.1 6.6 2.9 4.5 6.9 2.5 9.6 5.1 21.9 2.0 7.3 4.1 6.3 1.6 48.0 5.6 3.9 0.0 1.9 4.4 7.3 1.0 2.0 2.4 4.5 2.1 3.0 6.8 3.8 8.0 6.4 19.4 2.6 19.7 2.6 4.2 18.8 8.7 2.1 1.6 7.4 3.4 7.6 5.5 2.0 WDR38 ENSG00000136918 "WD repeat domain 38" Q5JTN6 9 124853417-124857890 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "fallopian tube: 77.7" "Cell type enhanced" "Detected in some" "Early spermatids: 26.9;Endometrial ciliated cells: 93.3;Late spermatids: 92.6;Respiratory ciliated cells: 127.9" "Cancer enhanced" "Detected in some" "endometrial cancer: 12.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA056607 Approved Vesicles NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "HPA056607: AB_2683188" "unprognostic (5.66e-3)" "unprognostic (2.15e-3)" "unprognostic (1.51e-2)" "prognostic favorable (3.97e-4)" "unprognostic (1.14e-1)" "unprognostic (2.17e-3)" "unprognostic (4.29e-3)" "unprognostic (7.90e-2)" "unprognostic (1.13e-1)" "unprognostic (3.82e-1)" "unprognostic (1.38e-1)" "unprognostic (5.90e-2)" "unprognostic (7.75e-5)" "unprognostic (1.01e-1)" "unprognostic (3.25e-2)" "unprognostic (6.36e-2)" "unprognostic (4.42e-2)" 0.0 0.0 2.1 0.0 2.0 0.0 0.0 2.3 1.3 2.4 16.3 0.0 0.0 0.7 0.0 0.0 77.7 0.0 0.1 2.2 4.0 0.1 0.0 5.2 0.0 8.2 9.8 0.0 0.0 0.0 0.3 0.0 6.5 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 7.2 0.0 0.0 7.6 3.3 0.1 0.2 0.0 0.0 0.0 0.0 4.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.0 2.3 1.3 2.2 4.0 8.2 9.8 6.5 7.2 3.3 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.2 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 26.9 93.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.2 0.0 0.0 92.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 127.9 0.0 0.0 0.0 2.8 1.6 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.2 WDR48 "KIAA1449, P80, SPG60" ENSG00000114742 "WD repeat domain 48" Q8TAF3 3 39052013-39096671 "Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Ubl conjugation pathway" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 104.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038421, HPA058015" Approved Supported Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "HPA038421: AB_10670780, HPA058015: AB_2683580" "unprognostic (1.95e-1)" "unprognostic (2.14e-1)" "unprognostic (2.99e-2)" "unprognostic (3.78e-1)" "unprognostic (7.68e-2)" "unprognostic (2.34e-3)" "unprognostic (6.14e-3)" "unprognostic (9.87e-3)" "unprognostic (8.02e-2)" "unprognostic (2.22e-2)" "unprognostic (2.28e-1)" "unprognostic (2.14e-2)" "prognostic favorable (1.63e-7)" "unprognostic (2.41e-1)" "unprognostic (2.94e-2)" "unprognostic (1.43e-1)" "unprognostic (1.69e-2)" 14.1 15.5 20.7 13.3 22.2 35.1 17.7 20.3 25.7 17.7 17.1 14.3 15.1 20.0 14.1 14.0 15.7 13.2 16.2 21.9 22.9 21.4 16.1 13.9 17.6 21.2 21.8 21.1 16.1 22.0 4.4 20.8 21.3 16.0 15.1 17.9 15.4 20.9 11.5 14.1 15.1 16.9 21.6 16.1 14.2 47.9 22.8 26.8 24.8 17.1 19.4 16.8 6.3 24.2 11.6 16.4 32.9 23.6 23.8 27.2 14.4 14.4 20.6 17.6 22.5 11.5 12.7 27.8 10.0 20.2 15.7 13.8 30.3 18.7 20.5 70.3 38.8 26.1 22.8 19.0 10.8 18.8 13.7 18.1 21.2 19.0 21.9 31.9 21.8 20.1 30.7 27.8 16.3 9.9 24.6 20.1 36.3 16.8 19.8 9.6 17.3 24.1 21.9 24.2 24.1 29.0 14.7 29.8 25.4 29.0 15.6 26.7 18.8 15.9 12.0 14.7 16.2 30.2 48.6 22.7 18.5 16.9 15.5 13.3 6.0 7.5 9.2 7.9 9.1 9.4 10.6 10.7 8.7 10.9 10.7 9.3 8.0 15.1 13.0 7.2 12.6 8.9 20.7 22.2 20.3 25.7 21.9 22.9 21.2 21.8 21.3 21.6 22.8 24.2 27.0 16.0 22.0 45.4 26.6 17.6 13.3 9.2 20.5 21.6 18.1 16.6 23.2 7.2 15.5 11.0 16.7 15.9 26.0 14.4 17.6 13.9 77.2 20.2 28.5 20.6 22.1 17.9 35.3 12.4 12.2 18.0 9.7 29.7 24.1 25.5 16.1 13.0 8.6 21.9 37.0 13.7 4.1 11.4 15.9 71.9 18.6 16.2 14.2 26.2 19.8 23.6 13.4 38.7 41.1 12.0 12.9 16.6 20.9 21.9 17.3 13.4 17.8 17.9 26.3 21.9 19.2 104.5 59.9 16.7 21.2 21.5 25.7 23.0 12.3 19.5 WDR54 FLJ12953 ENSG00000005448 "WD repeat domain 54" Q9H977 2 74421678-74425755 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 70.2" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 207.0;Late spermatids: 124.6;Respiratory ciliated cells: 395.9;Spermatocytes: 147.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043257, HPA053558" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" "Vesicles, Cytosol" "HPA043257: AB_10795981, HPA053558: AB_2682189" "unprognostic (1.12e-1)" "unprognostic (3.68e-1)" "unprognostic (1.45e-1)" "unprognostic (2.37e-2)" "unprognostic (2.62e-1)" "unprognostic (3.06e-3)" "unprognostic (4.10e-3)" "unprognostic (1.96e-1)" "unprognostic (2.68e-2)" "unprognostic (1.51e-1)" "unprognostic (7.25e-3)" "unprognostic (3.89e-2)" "unprognostic (3.07e-1)" "unprognostic (1.19e-1)" "unprognostic (1.61e-1)" "unprognostic (8.96e-2)" "unprognostic (4.85e-2)" 8.2 8.5 11.0 6.5 11.7 6.7 7.7 8.5 11.2 11.8 17.6 6.7 3.2 10.4 5.6 3.4 70.2 8.4 4.3 11.8 14.2 12.1 1.9 10.7 11.6 10.3 12.5 10.8 6.3 30.0 24.4 6.3 11.2 7.4 4.0 28.0 5.2 9.9 1.3 4.9 7.0 7.7 10.8 12.2 7.0 38.0 11.7 18.5 7.8 1.7 11.2 8.6 6.3 9.9 44.9 78.3 37.9 32.5 14.0 25.7 11.8 22.5 45.8 56.8 52.8 6.9 34.4 39.3 22.5 25.1 34.5 37.6 27.8 100.6 49.8 30.3 16.8 19.4 42.4 4.7 14.3 30.6 15.3 11.6 27.6 58.1 30.3 67.5 30.6 61.6 7.7 45.8 32.4 69.8 48.6 32.3 30.3 10.9 29.8 41.2 44.1 84.4 51.3 22.4 66.4 52.1 17.6 15.9 27.0 11.2 25.6 14.7 15.3 29.2 50.9 32.1 50.7 49.2 26.7 10.1 86.5 18.8 21.6 6.6 8.5 0.6 31.1 11.5 31.4 24.2 35.5 33.7 28.6 22.0 25.1 23.8 0.7 29.1 10.1 46.7 36.8 21.6 11.0 11.7 8.5 11.2 11.8 14.2 10.3 12.5 11.2 10.8 11.7 9.9 20.0 3.2 12.8 1.3 23.1 7.0 20.1 64.1 10.2 48.3 9.4 10.9 1.7 20.0 39.4 23.9 83.4 9.8 30.1 1.5 19.6 28.5 77.8 207.0 18.5 25.1 28.9 5.5 5.6 6.0 14.6 14.3 7.1 9.2 12.7 23.8 30.0 1.9 8.6 32.0 4.1 6.0 38.7 6.9 17.4 124.6 17.1 7.4 12.4 0.0 29.8 51.9 26.8 3.0 2.4 13.6 4.4 22.2 17.5 9.4 0.8 28.4 395.9 112.5 0.0 8.4 30.6 147.9 19.3 1.7 4.8 2.9 30.5 37.2 3.8 13.3 WDR72 FLJ38736 ENSG00000166415 "WD repeat domain 72" Q3MJ13 15 53513741-53762878 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Biomineralization "Amelogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 105.7;liver: 33.1;thyroid gland: 57.9" "Cell type enhanced" "Detected in some" "Cholangiocytes: 12.8;Collecting duct cells: 22.0;Glandular and luminal cells: 13.2;Hepatocytes: 44.3;Proximal tubular cells: 93.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 9.9;OE19: 18.3;RPMI-8226: 17.5;RPTEC TERT1: 10.1;SuSa: 15.2;U-266/70: 7.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048212, HPA057410, HPA059819" Uncertain Approved Vesicles NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "HPA048212: AB_2680315, HPA057410: AB_2683430, HPA059819: AB_2684133" "unprognostic (6.39e-4)" "unprognostic (1.41e-1)" "unprognostic (3.19e-2)" "unprognostic (1.79e-2)" "unprognostic (2.63e-2)" "unprognostic (3.37e-2)" "unprognostic (5.54e-2)" "unprognostic (2.20e-1)" "unprognostic (1.13e-1)" "unprognostic (1.26e-1)" "unprognostic (2.78e-2)" "unprognostic (1.09e-2)" "prognostic favorable (3.33e-16)" "unprognostic (2.83e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.80e-4)" "unprognostic (7.67e-2)" 0.1 0.0 0.1 0.2 0.1 0.0 0.8 0.0 0.1 7.2 0.0 0.6 2.6 1.4 0.5 0.4 2.6 3.9 0.1 0.0 0.1 105.7 33.1 0.8 0.1 0.1 0.4 0.2 3.5 1.8 0.3 0.1 0.1 0.1 0.8 0.7 18.4 0.6 0.0 2.0 0.9 0.0 0.0 0.1 1.1 0.5 0.1 0.0 57.9 0.0 0.0 1.7 0.0 0.3 0.0 9.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 3.2 0.1 6.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 3.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.9 18.3 0.1 0.0 0.1 17.5 10.1 3.5 1.9 0.0 0.0 0.1 0.0 15.2 2.4 0.0 0.1 0.3 0.5 0.0 0.1 7.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.4 0.1 0.0 0.1 0.3 0.1 6.4 3.6 0.0 0.5 0.1 1.1 0.0 0.6 0.5 0.0 0.1 0.6 12.8 0.0 22.0 0.0 0.6 0.0 0.2 9.8 3.2 1.2 4.9 1.0 0.1 0.0 0.0 0.4 0.5 2.1 0.2 0.0 13.2 0.0 0.0 0.0 44.3 0.1 3.3 0.5 0.0 0.0 0.6 0.0 0.3 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 93.2 0.1 0.1 0.0 0.0 0.1 1.0 1.6 0.9 0.4 0.1 0.7 0.0 0.3 6.4 WDR81 "CAMRQ2, FLJ33817, PPP1R166, SORF-2" ENSG00000167716 "WD repeat domain 81" Q562E7 17 1716523-1738599 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 27.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023044, HPA063703" Uncertain Approved Nucleoplasm,Vesicles,Cytosol "Intracellular and membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Vesicles, Cytosol" "HPA023044: AB_1858822, HPA063703: " "unprognostic (1.00e-1)" "unprognostic (4.67e-2)" "unprognostic (6.63e-2)" "unprognostic (4.90e-3)" "unprognostic (6.10e-2)" "unprognostic (7.75e-3)" "unprognostic (2.01e-1)" "unprognostic (2.09e-1)" "unprognostic (3.06e-2)" "unprognostic (1.60e-2)" "prognostic favorable (3.30e-4)" "unprognostic (3.26e-1)" "unprognostic (8.72e-2)" "unprognostic (2.25e-1)" "unprognostic (8.43e-2)" "unprognostic (7.99e-2)" "unprognostic (3.90e-2)" 17.7 16.2 4.5 4.6 5.4 4.9 16.9 4.6 6.3 18.2 6.6 11.5 4.8 18.9 2.4 9.9 17.4 1.6 10.9 4.3 4.4 11.9 32.8 13.7 5.6 5.9 5.1 21.4 11.0 2.4 13.1 3.9 5.3 16.0 1.7 0.8 11.0 5.9 18.2 18.4 17.8 5.1 4.7 24.3 11.0 7.5 6.1 6.6 10.5 2.1 4.2 15.4 13.7 6.4 0.7 12.3 1.7 9.1 12.4 7.0 9.2 0.9 0.2 0.6 0.0 1.8 4.4 4.9 6.5 5.4 6.2 12.2 6.3 8.4 0.4 9.5 12.8 0.3 8.8 5.9 22.1 4.1 7.6 17.8 8.8 5.9 4.1 1.9 5.0 3.7 1.0 6.3 7.6 6.8 1.3 7.6 3.9 4.2 9.4 6.4 2.9 6.8 3.7 2.0 2.2 5.0 4.3 3.4 15.4 0.1 6.0 6.1 6.8 4.8 5.4 7.9 6.7 0.5 1.3 3.1 7.7 5.9 2.4 0.0 1.4 2.8 1.1 2.3 1.3 1.3 1.2 1.2 1.8 1.0 0.8 1.1 0.3 2.1 2.3 3.3 1.2 1.1 4.5 5.4 4.6 6.3 4.3 4.4 5.9 5.1 5.3 4.7 6.1 6.4 6.3 12.8 10.3 6.5 4.2 2.5 2.9 4.4 8.6 4.5 4.8 5.3 3.6 4.3 3.8 0.0 4.2 2.5 9.9 6.8 1.9 3.1 0.7 2.1 6.2 5.4 1.2 14.3 5.3 4.5 1.9 8.2 6.6 2.9 4.5 6.2 4.6 27.7 23.8 5.0 5.3 4.6 10.2 22.3 4.5 1.2 16.4 15.3 0.0 9.4 7.5 2.5 9.2 5.0 7.6 4.8 4.8 15.1 5.3 2.9 8.7 20.1 6.4 1.8 19.7 5.9 4.5 0.7 2.0 3.4 1.7 2.3 4.7 5.8 4.4 1.7 WDR83 MORG1 ENSG00000123154 "WD repeat domain 83" Q9BRX9 19 12666802-12675832 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 61.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042629, HPA042838" Uncertain Approved "Nucleoplasm,Vesicles,Centriolar satellite" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 25: Spermatids - Spermatogenesis" Vesicles "Nucleoplasm, Centriolar satellite" "HPA042629: AB_10794763, HPA042838: AB_10794173" "unprognostic (1.12e-2)" "unprognostic (3.15e-3)" "unprognostic (1.43e-3)" "unprognostic (1.34e-2)" "unprognostic (1.36e-1)" "unprognostic (1.35e-2)" "unprognostic (2.64e-1)" "unprognostic (3.60e-3)" "unprognostic (2.52e-1)" "unprognostic (1.56e-2)" "prognostic favorable (5.44e-4)" "unprognostic (1.30e-2)" "unprognostic (4.07e-2)" "unprognostic (2.85e-2)" "unprognostic (1.18e-1)" "unprognostic (2.37e-1)" "prognostic favorable (3.12e-4)" 5.2 6.7 7.5 3.4 8.1 5.3 5.2 8.0 9.3 6.0 7.1 7.1 2.6 6.2 2.0 4.2 6.8 2.9 7.2 7.5 7.9 6.9 4.8 4.6 5.0 7.8 7.8 6.5 6.3 5.6 5.7 2.7 7.7 5.9 1.4 2.5 8.1 3.3 4.2 6.5 4.6 1.9 7.5 5.3 6.9 10.0 7.8 6.8 5.8 2.9 3.1 5.7 4.5 8.2 6.8 11.0 6.2 8.1 11.0 4.4 4.9 6.1 5.8 7.3 7.5 13.4 5.7 10.0 8.7 5.6 4.2 7.0 7.3 9.6 1.3 10.2 16.0 8.0 7.6 8.0 9.3 11.3 8.4 8.0 7.6 6.0 4.9 5.1 7.2 21.6 7.2 0.8 3.4 25.6 16.4 9.2 4.8 8.0 18.8 10.9 7.7 9.3 7.1 8.0 12.6 8.6 6.4 9.0 5.3 3.5 5.1 11.2 4.0 8.0 2.4 6.2 6.1 24.7 17.7 4.9 12.7 8.7 4.6 5.6 13.4 5.7 10.2 12.4 12.2 9.7 10.2 10.2 14.0 10.8 9.8 12.8 6.7 21.9 6.4 23.5 12.2 10.8 7.5 8.1 8.0 9.3 7.5 7.9 7.8 7.8 7.7 7.5 7.8 8.2 10.8 0.0 14.4 4.2 13.5 15.4 12.1 15.9 11.4 21.1 10.1 9.8 4.4 17.2 12.0 18.4 12.5 12.4 22.3 9.0 17.6 15.6 17.8 12.2 7.3 12.0 9.6 16.2 7.2 17.5 13.9 9.9 9.2 6.1 14.0 12.4 8.6 9.2 13.2 20.2 7.1 7.8 16.2 11.6 19.2 61.9 15.8 9.6 16.0 1.9 17.8 18.2 24.7 4.5 4.4 13.5 5.8 18.0 11.6 15.4 13.6 33.7 18.4 22.7 19.7 8.1 11.3 25.8 17.6 8.3 16.1 9.0 12.4 10.1 9.6 14.6 WDTC1 "ADP, DCAF9, KIAA1037" ENSG00000142784 "WD and tetratricopeptide repeats 1" Q8N5D0 1 27234632-27308636 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028177, HPA028180, HPA028182" Uncertain Supported "Golgi apparatus,Vesicles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 46: Photoreceptor cells - Phototransduction" Vesicles "Golgi apparatus" "HPA028177: AB_10600419, HPA028180: AB_10601676, HPA028182: AB_10602204" "unprognostic (3.18e-2)" "prognostic favorable (4.51e-4)" "unprognostic (5.69e-2)" "unprognostic (8.28e-2)" "unprognostic (3.31e-2)" "unprognostic (2.00e-3)" "unprognostic (1.25e-2)" "unprognostic (9.44e-2)" "unprognostic (2.44e-1)" "unprognostic (5.45e-3)" "unprognostic (1.41e-3)" "unprognostic (1.73e-1)" "prognostic favorable (8.84e-8)" "unprognostic (1.28e-1)" "unprognostic (9.33e-2)" "unprognostic (3.01e-2)" "unprognostic (2.51e-2)" 16.5 24.4 25.4 10.5 22.3 14.7 17.5 20.2 25.4 18.9 12.7 24.7 12.9 19.7 7.0 18.0 19.9 10.5 35.9 21.8 20.0 19.9 18.7 16.9 14.4 25.3 21.0 19.0 22.1 47.7 16.9 10.6 24.4 19.3 9.5 33.5 20.1 15.1 63.0 24.8 18.0 12.0 19.4 17.7 23.2 37.6 23.5 19.8 18.4 54.4 12.7 19.8 18.5 21.1 19.8 8.6 13.5 1.3 18.9 15.8 5.6 12.0 20.1 12.7 15.5 2.9 19.3 17.0 14.0 24.0 9.3 10.1 13.0 18.4 11.0 23.2 22.0 17.7 8.9 7.9 17.0 9.0 22.4 15.1 29.6 15.8 14.4 22.9 17.4 5.4 18.2 17.2 13.6 11.1 14.6 21.6 6.3 13.0 18.1 7.3 10.1 18.7 15.2 4.2 19.7 16.9 15.7 6.6 14.4 10.1 9.8 15.5 15.2 10.3 6.2 14.5 5.9 24.7 14.2 8.1 20.8 17.3 12.5 0.1 0.2 2.7 1.4 0.3 0.5 0.6 0.3 0.6 0.7 0.4 0.2 0.6 2.1 0.4 0.2 0.5 0.4 0.5 25.4 22.3 20.2 25.4 21.8 20.0 25.3 21.0 24.4 19.4 23.5 21.1 10.8 9.6 10.7 19.6 13.8 12.9 10.3 8.4 16.5 31.4 18.5 14.5 15.6 14.3 7.6 31.3 54.2 14.2 14.3 17.3 9.8 15.1 29.8 15.3 8.2 10.1 16.7 32.8 22.4 14.1 4.8 10.6 16.3 13.2 1.3 15.4 18.5 16.6 13.0 21.9 21.2 16.9 6.1 21.0 11.3 66.2 17.1 15.8 10.6 19.7 18.9 15.8 28.8 16.6 22.2 16.0 10.1 16.6 12.3 17.2 26.6 19.1 18.4 70.0 6.6 17.1 10.3 30.9 6.6 13.0 17.3 16.4 13.3 14.1 15.0 16.8 WNK3 PRKWNK3 ENSG00000196632 "WNK lysine deficient protein kinase 3" Q9BYP7 X 54192823-54358642 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 11.7;testis: 9.9" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 193.3;Granulosa cells: 199.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.5;AN3-CA: 3.4;HAP1: 5.2;NTERA-2: 9.1;SiHa: 4.5;SuSa: 3.8;U-2 OS: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077678 Approved Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA077678: AB_2686850" "unprognostic (1.86e-1)" "unprognostic (1.68e-3)" "unprognostic (2.44e-1)" "unprognostic (7.87e-5)" "unprognostic (4.82e-3)" "unprognostic (1.85e-3)" "unprognostic (1.85e-2)" "unprognostic (3.32e-2)" "unprognostic (3.38e-1)" "unprognostic (3.03e-2)" "unprognostic (5.78e-4)" "unprognostic (2.22e-1)" "unprognostic (2.64e-2)" "unprognostic (5.61e-2)" "unprognostic (9.99e-2)" "unprognostic (7.63e-2)" "unprognostic (8.74e-2)" 0.2 2.5 1.6 0.1 1.7 0.1 0.6 0.3 1.9 0.6 0.0 0.3 0.2 0.5 11.7 0.2 0.8 0.3 0.7 1.0 4.6 1.0 3.6 0.3 0.1 1.6 4.8 3.0 0.3 0.9 2.4 0.3 2.4 0.9 0.0 3.3 0.3 0.8 0.1 0.3 0.2 0.5 0.6 0.2 0.6 9.9 4.5 0.1 0.6 0.1 0.1 0.5 0.4 1.2 0.0 0.0 4.5 3.4 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 5.2 0.1 0.2 0.0 0.9 0.0 0.0 0.1 0.1 0.0 0.1 0.3 0.0 0.1 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 2.2 0.6 0.0 0.9 0.1 1.4 1.3 4.5 0.0 0.5 3.8 0.4 0.0 0.2 0.0 3.9 0.0 1.0 0.0 3.3 0.0 1.2 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.7 0.3 1.9 1.0 4.6 1.6 4.8 2.4 0.6 4.5 1.2 1.9 0.0 2.3 18.3 0.7 3.7 4.3 0.3 9.1 24.9 5.8 6.9 193.3 2.8 3.2 7.3 14.6 0.2 0.0 0.1 5.9 1.7 6.4 2.0 7.8 8.5 0.0 0.8 14.5 0.0 0.3 6.7 0.0 4.9 6.3 199.5 20.3 48.3 0.1 35.3 29.7 0.0 2.0 0.8 1.5 20.4 15.8 0.6 0.0 3.7 0.0 19.5 0.0 48.2 19.2 0.2 0.0 43.6 0.0 6.0 0.0 3.9 0.2 43.3 6.6 4.8 10.5 43.8 46.3 2.1 1.1 0.1 1.5 9.8 0.0 1.4 WNT2 "INT1L1, IRP" ENSG00000105989 "Wnt family member 2" P09544 7 117275451-117323152 "Cancer-related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "placenta: 39.9" "Cell type enhanced" "Detected in some" "Early spermatids: 30.9;Endometrial stromal cells: 33.1;Fibroblasts: 82.5;Late spermatids: 14.7;Spermatocytes: 13.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-2197: 11.5" "Region enhanced" "Detected in many" "basal ganglia: 12.6" "Low region specificity" "Detected in many" HPA020920 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Vesicles "HPA020920: AB_1858850" "unprognostic (1.90e-1)" "unprognostic (6.97e-2)" "unprognostic (2.88e-2)" "unprognostic (4.11e-3)" "unprognostic (9.14e-2)" "unprognostic (2.47e-1)" "unprognostic (2.54e-2)" "unprognostic (2.75e-1)" "unprognostic (2.74e-1)" "unprognostic (5.70e-2)" "unprognostic (1.36e-2)" "unprognostic (1.41e-1)" "unprognostic (3.43e-1)" "unprognostic (4.05e-2)" "unprognostic (2.50e-2)" "unprognostic (1.05e-1)" "unprognostic (2.10e-1)" 1.2 0.0 0.2 0.1 0.4 0.0 0.8 0.1 0.7 3.5 0.3 0.1 0.0 8.6 0.1 0.0 0.8 0.2 0.4 0.4 0.3 0.1 0.5 6.9 0.0 0.1 0.5 0.3 0.1 0.0 0.1 39.9 0.1 3.2 0.0 0.0 0.0 0.4 0.0 0.7 0.0 1.1 0.1 0.9 0.0 0.5 1.5 0.0 0.1 0.0 0.0 1.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.8 1.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.1 0.7 0.4 0.3 0.1 0.5 0.1 0.1 1.5 0.2 0.5 0.0 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.2 0.1 0.3 0.0 1.3 0.0 0.0 3.7 0.0 0.0 0.0 0.0 30.9 0.8 33.1 9.8 0.0 0.0 1.4 0.0 3.6 82.5 0.0 0.6 0.0 0.0 10.8 0.6 7.7 0.0 0.5 0.0 0.0 0.8 0.3 14.7 1.5 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.7 13.6 0.5 0.0 2.7 9.0 0.2 0.0 0.0 0.2 WNT2B "WNT13, XWNT2" ENSG00000134245 "Wnt family member 2B" Q93097 1 112466541-112530165 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Leydig cells: 80.2;Peritubular cells: 197.5" "Cancer enhanced" "Detected in many" "testis cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 4.4;HSkMC: 8.0;SuSa: 3.4;TIME: 3.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047274, HPA066368" Approved Nucleoplasm,Vesicles "Secreted to extracellular matrix" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles Nucleoplasm "HPA047274: AB_2732539, HPA066368: AB_2685664" "unprognostic (2.08e-3)" "unprognostic (2.06e-3)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (1.77e-1)" "unprognostic (1.49e-1)" "unprognostic (9.42e-2)" "unprognostic (4.90e-3)" "unprognostic (1.15e-1)" "unprognostic (2.37e-1)" "unprognostic (5.94e-2)" "unprognostic (1.13e-1)" "unprognostic (5.65e-4)" "unprognostic (5.41e-2)" "unprognostic (7.64e-2)" "unprognostic (4.80e-2)" "unprognostic (2.49e-2)" 4.5 1.9 2.0 1.5 4.9 0.1 2.8 2.1 2.8 8.2 2.0 5.6 3.0 4.9 2.8 5.8 4.7 2.8 4.3 1.9 1.7 2.4 1.0 6.3 0.8 1.8 1.7 10.9 1.8 0.6 2.3 4.8 1.9 6.1 5.3 5.5 2.2 13.9 1.6 11.1 5.2 2.2 1.4 1.7 3.8 3.8 1.8 0.2 1.9 0.8 0.7 5.6 9.1 2.3 0.4 0.3 2.2 0.5 2.2 4.4 0.4 1.0 1.0 0.2 0.4 0.2 0.5 1.1 0.2 1.1 0.2 1.4 0.7 0.3 0.2 0.0 0.4 0.1 0.8 0.3 1.8 0.2 0.5 8.0 0.8 0.4 0.1 1.3 1.2 0.3 0.1 0.2 0.2 0.3 0.1 0.1 0.3 0.0 0.3 0.1 0.3 0.0 1.5 0.3 0.3 0.3 0.7 0.1 0.7 3.4 0.0 0.2 3.5 0.3 1.4 0.8 0.3 0.1 0.1 0.0 0.9 0.1 0.9 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 2.0 4.9 2.1 2.8 1.9 1.7 1.8 1.7 1.9 1.4 1.8 2.3 7.6 12.8 3.3 2.0 2.0 10.1 1.8 6.1 5.2 14.1 2.1 0.9 6.5 1.5 3.9 1.8 27.1 2.1 2.4 3.5 0.0 0.8 5.6 2.6 3.6 10.2 8.4 2.1 5.5 1.4 0.8 17.7 1.1 6.8 2.5 2.8 6.1 0.2 1.1 5.0 6.2 2.2 4.1 2.1 8.2 3.4 80.2 4.0 3.6 30.9 2.2 9.8 0.0 11.6 7.1 2.0 4.8 197.5 2.5 4.4 2.9 0.9 4.6 27.6 0.0 9.7 2.7 5.9 5.5 26.4 13.9 1.9 1.9 2.0 1.5 2.6 WNT3 "INT4, MGC131950, MGC138321, MGC138323" ENSG00000108379 "Wnt family member 3" P56703 17 46762506-46833154 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "liver: 12.3;skin 1: 27.7" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 44.5;Early spermatids: 27.7;Late spermatids: 63.8;Suprabasal keratinocytes: 17.6" "Cancer enriched" "Detected in many" 6 "testis cancer: 13.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 8.5;U-698: 14.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA049893 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 28: Keratinocytes - Keratinization" Vesicles "HPA049893: " "unprognostic (1.84e-1)" "unprognostic (2.90e-2)" "unprognostic (2.35e-1)" "unprognostic (6.41e-4)" "unprognostic (4.73e-2)" "unprognostic (5.26e-2)" "unprognostic (1.33e-1)" "unprognostic (1.26e-1)" "unprognostic (4.97e-2)" "unprognostic (2.20e-2)" "unprognostic (2.16e-1)" "unprognostic (2.66e-1)" "unprognostic (1.10e-8)" "unprognostic (1.77e-1)" "unprognostic (2.08e-1)" "unprognostic (1.61e-1)" "unprognostic (1.38e-1)" 0.8 0.4 1.3 0.4 1.1 0.1 1.0 0.7 1.0 1.0 0.2 0.6 3.4 0.5 0.0 1.3 0.5 0.1 0.9 0.8 1.2 1.7 12.3 0.9 0.2 1.4 1.8 0.5 0.8 2.5 1.7 0.2 1.2 1.3 0.2 0.2 1.2 0.0 0.2 27.7 2.7 0.2 0.7 0.7 0.4 4.4 4.4 0.1 1.3 0.0 0.1 0.4 1.1 0.7 3.9 1.7 8.5 0.0 0.1 0.1 0.7 0.8 0.9 3.0 0.0 2.7 1.7 1.6 2.3 2.1 6.1 1.3 0.4 0.0 3.9 0.0 0.4 0.0 3.0 2.3 0.0 0.1 0.1 0.2 1.8 1.1 2.3 3.5 1.1 2.5 1.5 0.0 1.0 1.7 0.0 1.4 0.0 1.0 2.4 2.9 1.9 0.2 0.6 0.0 0.1 0.7 1.6 0.0 1.2 2.1 0.0 4.0 0.2 3.2 2.1 0.4 1.5 0.6 0.2 14.0 0.4 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 1.3 1.1 0.7 1.0 0.8 1.2 1.4 1.8 1.2 0.7 4.4 0.7 0.2 0.0 1.5 3.9 0.5 44.5 0.6 0.6 3.4 1.1 3.0 1.7 1.3 1.5 0.4 0.0 0.0 2.2 0.1 0.7 1.9 0.7 27.7 0.1 0.7 0.5 0.0 0.0 5.4 2.5 0.1 1.1 0.0 0.2 0.0 0.7 0.4 4.0 0.2 8.4 4.3 0.6 0.0 0.0 1.5 63.8 0.3 0.1 1.8 1.0 0.6 0.2 0.0 4.0 1.1 2.9 1.4 0.4 0.0 1.2 3.7 0.5 0.3 0.8 0.0 1.4 1.1 0.9 2.9 0.8 17.6 0.3 0.0 0.3 0.9 0.3 WNT3A ENSG00000154342 "Wnt family member 3A" P56704 1 228006998-228061271 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "placenta: 15.7" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 12.8;Basal keratinocytes: 3.4;Basal prostatic cells: 3.1;Basal squamous epithelial cells: 8.6;Syncytiotrophoblasts: 2.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HEK 293: 1.1;U-2 OS: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA049893 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 9: U-2 OS - Unknown function" "Cluster 11: Alveolar cells - Smell perception" Vesicles "HPA049893: " "unprognostic (9.84e-3)" "prognostic favorable (6.11e-5)" "unprognostic (2.40e-1)" "unprognostic (3.37e-1)" "unprognostic (7.82e-2)" "unprognostic (4.94e-2)" "unprognostic (2.19e-1)" "unprognostic (1.96e-1)" "unprognostic (4.22e-2)" "unprognostic (4.12e-2)" "unprognostic (2.16e-1)" "unprognostic (4.80e-3)" "unprognostic (1.99e-1)" "unprognostic (7.26e-2)" "unprognostic (5.43e-3)" "unprognostic (1.54e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 15.7 0.0 1.3 0.0 0.0 0.9 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 0.0 0.0 0.0 3.4 3.1 1.2 8.6 0.0 0.0 0.1 1.9 0.0 0.9 1.8 0.0 2.0 0.0 0.4 0.0 0.1 0.3 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.8 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.5 1.0 2.9 0.0 0.0 0.1 0.5 WNT4 WNT-4 ENSG00000162552 "Wnt family member 4" P56705 1 22117313-22143969 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 40.8" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 42.1;Breast glandular cells: 19.9;Breast myoepithelial cells: 24.3;Endometrial stromal cells: 71.4;Enteroendocrine cells: 29.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 8.5;SCLC-21H: 10.2;SK-BR-3: 8.6;T-47d: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA011397 Uncertain Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "HPA011397: AB_1858854" "unprognostic (1.85e-1)" "unprognostic (9.08e-2)" "unprognostic (6.67e-3)" "unprognostic (1.75e-2)" "unprognostic (7.17e-2)" "unprognostic (4.30e-3)" "unprognostic (2.77e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (5.34e-4)" "unprognostic (2.14e-2)" "prognostic favorable (4.90e-4)" "unprognostic (1.01e-1)" "unprognostic (2.95e-2)" "unprognostic (4.21e-1)" "unprognostic (2.32e-1)" "unprognostic (4.74e-2)" "unprognostic (9.49e-2)" 0.8 9.0 2.4 0.4 1.5 0.3 2.2 0.2 2.9 8.9 0.5 2.3 3.2 4.5 8.9 12.1 8.3 2.6 0.1 2.0 2.9 1.1 1.4 1.2 0.1 1.6 1.8 16.8 3.0 0.1 5.6 1.6 1.2 5.5 1.6 0.2 4.1 2.6 3.1 40.8 3.1 1.9 1.1 0.3 4.3 0.6 3.9 1.1 3.4 0.6 1.5 3.1 6.3 1.1 1.3 0.1 2.5 0.1 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.0 0.7 0.0 0.8 0.0 0.3 8.5 0.0 0.6 0.0 0.2 0.3 0.3 0.2 0.0 0.2 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 1.1 0.2 0.3 0.0 0.0 0.0 1.6 10.2 0.0 0.1 8.6 0.6 0.6 3.4 0.0 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 1.5 0.2 2.9 2.0 2.9 1.6 1.8 1.2 1.1 3.9 1.1 0.9 3.2 8.6 0.3 0.7 16.7 4.3 42.1 6.8 0.0 19.9 24.3 0.6 0.0 15.2 0.0 0.0 0.7 0.1 0.9 0.0 2.7 0.1 4.1 71.4 0.6 29.4 0.0 0.2 0.6 0.1 3.1 0.5 1.6 0.0 0.2 0.7 0.5 0.1 0.0 1.9 16.0 4.1 0.0 0.2 0.9 0.0 0.4 5.4 6.5 0.1 0.0 0.0 0.0 0.3 0.9 0.1 3.8 0.6 5.7 0.3 0.0 12.0 0.0 0.0 0.4 2.2 0.0 0.3 2.5 10.4 0.3 0.6 0.0 0.6 4.2 WNT5B ENSG00000111186 "Wnt family member 5B" Q9H1J7 12 1529891-1647212 "Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 32.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 25.6;Microglial cells: 19.7;Muller glia cells: 40.4;Urothelial cells: 16.2" "Cancer enhanced" "Detected in all" "testis cancer: 15.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.8;eosinophil: 1.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 231.4;BJ hTERT+: 143.5;BJ hTERT+ SV40 Large T+: 165.4;BJ hTERT+ SV40 Large T+ RasG12V: 136.4;fHDF/TERT166: 162.6;HBF TERT88: 144.1;hTEC/SVTERT24-B: 144.8;U-138 MG: 142.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA061991 Approved Vesicles "Secreted to extracellular matrix" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 5: Muller glia cells - Visual perception" Vesicles "HPA061991: " "unprognostic (7.44e-2)" "unprognostic (5.59e-2)" "unprognostic (8.14e-2)" "unprognostic (3.69e-2)" "unprognostic (1.12e-1)" "unprognostic (1.45e-1)" "unprognostic (5.53e-3)" "unprognostic (1.26e-1)" "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (4.08e-2)" "unprognostic (2.16e-2)" "unprognostic (1.49e-3)" "unprognostic (1.90e-1)" "unprognostic (2.93e-2)" "unprognostic (2.77e-1)" "unprognostic (2.71e-2)" 3.0 2.3 3.6 4.1 4.1 0.5 3.0 2.8 3.7 5.5 1.8 24.6 4.3 7.2 5.0 14.9 6.2 2.8 4.0 2.8 5.3 1.9 4.6 3.0 2.6 4.7 3.9 8.2 1.5 9.0 11.2 3.9 4.6 32.4 5.8 5.4 15.7 20.0 1.4 5.3 5.0 5.4 3.9 5.2 6.4 1.8 4.2 3.7 2.0 6.7 3.0 13.9 9.7 3.1 0.3 0.1 1.4 0.2 34.6 61.2 0.0 231.4 143.5 165.4 136.4 8.7 0.9 2.9 0.4 162.6 111.1 3.5 3.3 0.0 144.1 55.0 7.9 12.8 0.0 0.0 8.5 0.2 0.1 51.3 3.3 144.8 41.3 66.6 0.0 0.1 9.5 51.9 39.4 0.1 0.0 0.3 5.7 0.2 0.5 0.0 2.3 4.0 2.0 0.0 1.0 3.2 4.9 0.5 0.2 17.7 0.2 0.9 0.0 142.4 5.9 56.7 119.7 13.9 2.2 0.7 13.9 0.0 1.5 0.0 1.8 1.5 0.0 0.8 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 3.6 4.1 2.8 3.7 2.8 5.3 4.7 3.9 4.6 3.9 4.2 3.1 0.9 0.0 0.6 7.5 1.5 0.9 11.0 1.9 25.6 1.8 0.7 6.5 2.2 0.0 3.3 0.0 0.0 1.0 0.2 2.4 0.0 1.1 0.2 1.7 10.4 1.4 0.0 0.0 6.9 0.7 1.1 8.0 0.5 2.7 0.0 0.3 0.4 1.7 5.3 0.0 7.9 1.9 2.0 2.1 2.9 0.5 2.1 2.7 3.6 19.7 4.1 40.4 0.0 4.0 5.6 2.8 5.0 2.6 4.5 8.8 1.0 0.2 4.3 2.7 6.6 7.9 4.3 0.7 5.7 7.7 1.3 0.7 0.2 0.0 1.7 16.2 XAB2 "HCNP, HCRN, NTC90, SYF1" ENSG00000076924 "XPA binding protein 2" Q9HCS7 19 7619525-7629545 "Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, mRNA processing, mRNA splicing, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 159.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048751 Supported Nucleoplasm,Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 71: Testis - DNA repair" "Cluster 29: U-266 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm Vesicles "HPA048751: AB_2680512" "unprognostic (1.13e-1)" "prognostic favorable (4.04e-4)" "unprognostic (1.99e-3)" "prognostic favorable (4.96e-4)" "unprognostic (1.35e-1)" "unprognostic (4.98e-3)" "unprognostic (4.95e-2)" "unprognostic (4.56e-3)" "unprognostic (1.40e-1)" "unprognostic (2.10e-1)" "prognostic favorable (7.47e-4)" "unprognostic (2.69e-1)" "unprognostic (7.43e-3)" "unprognostic (3.88e-2)" "unprognostic (1.61e-1)" "unprognostic (1.51e-1)" "unprognostic (1.80e-3)" 29.4 23.6 17.7 15.1 19.9 44.5 30.6 19.6 24.8 37.0 16.9 28.3 17.5 33.8 6.9 25.4 32.0 11.8 24.3 17.8 17.9 27.7 27.8 27.2 20.7 19.9 18.0 45.8 35.9 13.4 27.1 15.4 20.2 32.7 5.4 9.0 31.1 17.5 35.6 39.0 27.6 9.3 18.6 34.5 30.9 37.7 18.3 21.1 34.7 13.3 10.6 29.1 29.6 25.5 39.8 35.7 21.2 27.9 21.9 16.3 41.2 22.8 26.5 39.6 40.0 46.4 25.4 26.7 44.1 21.3 28.9 34.2 30.2 33.2 10.0 47.1 39.0 35.5 30.2 41.3 28.3 47.5 30.8 28.8 27.0 28.0 20.2 21.3 24.2 56.4 32.4 69.0 12.4 44.0 44.9 73.8 48.3 24.8 69.6 49.3 26.8 47.0 15.8 30.7 30.2 34.4 25.9 25.1 23.2 13.8 32.0 41.6 24.1 18.1 29.5 41.3 39.0 117.7 75.0 39.0 31.0 40.1 27.4 8.8 10.0 9.3 11.8 10.2 11.3 10.1 11.0 9.1 8.0 12.2 13.1 10.0 6.4 8.3 13.9 6.9 14.2 12.1 17.7 19.9 19.6 24.8 17.8 17.9 19.9 18.0 20.2 18.6 18.3 25.5 18.3 0.0 1.8 3.9 22.9 19.6 16.2 28.1 14.2 14.1 89.4 54.4 1.4 25.8 20.1 47.8 12.5 46.0 24.8 28.3 35.2 19.8 39.9 24.7 13.3 16.4 18.6 14.1 2.3 34.4 26.4 16.7 33.6 32.3 19.7 27.7 17.5 46.4 19.8 3.3 2.5 21.2 24.4 19.2 11.0 19.1 28.3 18.3 26.6 3.7 26.5 13.9 23.7 1.0 3.7 15.1 12.4 21.8 19.4 12.2 28.9 159.5 13.4 14.2 39.5 15.9 21.6 36.1 57.3 14.6 17.8 65.9 20.6 17.8 23.9 14.3 XAGE2 "CT12.2, GAGED3, XAGE-2, XAGE2B" ENSG00000155622 "X antigen family member 2" Q96GT9 X 52369021-52375680 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "placenta: 199.5" "Group enriched" "Detected in some" 13 "Cytotrophoblasts: 1027.3;Extravillous trophoblasts: 1890.1;Syncytiotrophoblasts: 1367.6" "Cancer enhanced" "Detected in many" "ovarian cancer: 4.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 96.3;SK-BR-3: 22.7;SuSa: 27.9;T-47d: 20.1" "HPA052507, HPA060900" Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "Plasma membrane" "HPA052507: AB_2681855, HPA060900: AB_2684383" "unprognostic (1.21e-1)" "unprognostic (9.67e-2)" "unprognostic (1.49e-1)" "unprognostic (4.47e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 5.6 0.0 0.0 0.0 0.1 0.4 0.0 0.0 199.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 96.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 4.3 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 22.7 1.2 27.9 20.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 38.5 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1027.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 1890.1 6.7 0.0 0.0 0.0 0.0 0.0 0.0 107.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.0 0.2 2.1 0.0 0.0 1367.6 0.0 0.0 0.0 0.0 XAGE3 "CT12.3a, CT12.3b, GAGED4, PLAC6, pp9012, XAGE-3" ENSG00000171402 "X antigen family member 3" Q8WTP9 X 52862525-52868083 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 121 "placenta: 382.1" "Group enriched" "Detected in some" 10 "Cytotrophoblasts: 2223.5;Extravillous trophoblasts: 1309.1;Syncytiotrophoblasts: 2678.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.1;U-266/70: 2.2;U-266/84: 2.1" "HPA052507, HPA060900" Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 29: U-266 - Adaptive immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "Plasma membrane" "HPA052507: AB_2681855, HPA060900: AB_2684383" "unprognostic (6.04e-2)" "unprognostic (2.30e-1)" "unprognostic (2.92e-1)" 3.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 2.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.0 382.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.4 0.2 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 2.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2223.5 0.0 0.1 0.0 0.2 0.3 0.1 0.0 4.5 0.0 0.0 0.0 0.4 1309.1 11.1 0.0 0.3 0.0 0.0 0.0 4.6 191.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 15.1 7.0 0.0 0.0 2678.1 0.0 0.0 0.1 0.0 XAGE5 "CT12.5, GAGED5, XAGE-5" ENSG00000171405 "X antigen family member 5" Q8WWM1 X 52812204-52818301 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "testis: 1.1" "Cell type enhanced" "Detected in some" "Spermatocytes: 3.8;Spermatogonia: 9.0;Syncytiotrophoblasts: 1.9" "Cancer enriched" "Detected in single" 4 "liver cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 30 "U-2 OS: 22.0" "HPA052507, HPA055941" Uncertain Approved Nucleoplasm,Vesicles No No "Cluster 78: Testis - Spermatogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoplasm, Vesicles" "HPA052507: AB_2681855, HPA055941: AB_2682978" "unprognostic (1.89e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 9.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 XK "Kx, NA, NAC, X1k, XKR1" ENSG00000047597 "X-linked Kx blood group" P51811 X 37685791-37732130 "Blood group antigen proteins, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Blood group antigen" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.2;intestine: 12.2;stomach 1: 11.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 26.7;Erythroid cells: 63.5;Gastric mucus-secreting cells: 17.9;Proximal enterocytes: 21.5;Undifferentiated cells: 14.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 6.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 53 "basophil: 10.2;eosinophil: 5.8" "Lineage enriched" "Detected in single" 102 "granulocytes: 10.2" "Cell line enhanced" "Detected in many" "HEL: 44.4;HL-60: 23.2;K-562: 29.1;NB-4: 21.1;RPMI-8226: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019036 Approved Approved Nucleoplasm,Vesicles,Mitochondria No No "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" Mitochondria "Nucleoplasm, Vesicles" "HPA019036: AB_1846286" "unprognostic (2.37e-2)" "unprognostic (7.13e-3)" "unprognostic (5.03e-2)" "unprognostic (1.00e-2)" "unprognostic (7.97e-2)" "unprognostic (4.56e-1)" "unprognostic (3.59e-2)" "unprognostic (4.00e-2)" "unprognostic (4.77e-3)" "unprognostic (5.07e-2)" "unprognostic (6.63e-2)" "unprognostic (5.90e-2)" "unprognostic (4.44e-8)" "unprognostic (1.74e-1)" "unprognostic (4.75e-2)" "unprognostic (1.06e-1)" "unprognostic (1.43e-1)" 0.2 2.1 2.5 1.4 2.5 14.2 0.7 2.3 3.0 1.2 0.2 12.2 10.8 0.7 0.5 2.0 3.8 0.9 4.3 3.2 4.9 0.9 0.8 1.0 0.2 1.6 0.9 0.7 4.9 0.7 1.3 0.7 2.0 1.5 11.2 2.1 1.2 0.9 5.4 0.7 10.6 1.8 0.5 0.5 11.5 1.4 2.8 0.2 0.9 5.8 0.5 1.1 0.8 1.4 17.4 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.9 14.7 0.3 0.0 0.8 2.7 15.4 0.1 0.0 0.0 4.2 44.4 2.4 0.0 0.0 23.2 3.5 0.0 0.8 0.0 0.0 0.0 0.0 0.0 29.1 10.9 0.1 1.7 0.2 21.1 5.5 0.7 5.6 0.0 0.0 20.2 0.0 1.1 4.1 0.1 0.8 1.4 0.1 0.9 2.1 5.6 0.0 0.0 0.8 0.0 2.4 9.3 16.5 0.0 0.2 12.1 0.1 10.2 0.0 5.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 2.5 2.5 2.3 3.0 3.2 4.9 1.6 0.9 2.0 0.5 2.8 1.4 0.0 0.0 1.1 2.6 0.8 0.4 0.4 0.1 1.2 0.7 1.1 0.8 7.9 0.0 0.1 0.0 6.2 0.3 0.1 26.7 0.0 0.0 1.2 4.0 0.1 0.3 6.1 63.5 11.0 3.1 0.1 0.6 17.9 0.9 0.0 0.1 0.0 0.9 0.1 3.3 12.6 10.9 2.0 0.3 0.0 0.4 0.0 0.2 1.8 1.9 0.0 0.0 0.0 4.5 1.2 1.1 9.2 0.7 2.2 0.9 21.5 0.1 1.7 1.4 0.0 0.7 1.3 10.2 6.1 3.8 1.1 0.0 0.3 0.1 14.7 1.5 XKR4 KIAA1889 ENSG00000206579 "XK related 4" Q5GH76 8 55102028-55542054 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 8.1" "Group enriched" "Detected in some" 19 "Excitatory neurons: 306.3;Inhibitory neurons: 1019.5;Oligodendrocyte precursor cells: 721.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "REH: 2.6;RPTEC TERT1: 9.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025072, HPA028083" Uncertain Approved Vesicles NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "HPA025072: AB_1858886, HPA028083: AB_10601025" "unprognostic (7.15e-4)" "unprognostic (1.28e-3)" "unprognostic (6.98e-2)" "unprognostic (5.63e-3)" "unprognostic (7.39e-2)" "unprognostic (5.68e-3)" "unprognostic (6.33e-2)" "unprognostic (5.14e-2)" "unprognostic (1.88e-1)" "unprognostic (2.63e-1)" "unprognostic (2.38e-3)" "unprognostic (6.63e-2)" "unprognostic (3.46e-4)" "unprognostic (2.08e-2)" "unprognostic (2.39e-2)" "unprognostic (7.36e-2)" "unprognostic (4.96e-2)" 0.1 0.2 7.6 0.5 7.1 0.0 0.0 0.9 8.1 0.3 0.0 1.7 0.2 0.1 0.2 0.5 0.1 0.2 0.7 7.0 2.2 0.1 0.0 0.0 0.4 0.1 2.2 0.0 0.2 0.0 0.7 0.0 0.0 0.3 0.4 0.6 0.3 0.5 0.0 0.2 0.3 0.1 0.0 0.1 0.3 0.1 5.8 0.5 0.0 0.0 0.4 0.3 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 2.6 0.0 0.0 9.9 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 7.6 7.1 0.9 8.1 7.0 2.2 0.1 2.2 0.0 0.0 5.8 1.1 0.5 9.6 18.7 7.8 0.1 0.4 0.6 0.0 0.6 12.5 0.1 0.3 2.1 0.0 9.3 3.7 35.5 0.1 0.4 0.1 0.0 0.1 0.9 0.6 0.2 2.4 0.0 0.0 306.3 0.9 0.1 2.3 0.0 1.1 0.0 0.2 1.1 0.4 0.1 0.0 1019.5 0.0 0.0 0.0 1.0 0.0 0.0 1.4 8.8 30.0 1.8 0.6 0.0 721.3 9.4 0.4 0.0 0.0 0.4 0.6 0.0 0.1 5.2 1.6 0.0 2.6 0.4 1.1 0.1 0.2 0.9 0.1 0.5 0.1 0.0 0.7 XPO1 "CRM-1, CRM1, emb" ENSG00000082898 "Exportin 1" O14980 2 61476032-61538741 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Transport" RNA-binding "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010184, HPA042933" Supported Enhanced "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA 410000 "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Nuclear membrane" "Vesicles, Cytosol" "CAB010184: AB_2215817, HPA042933: AB_2678229" "unprognostic (7.34e-2)" "unprognostic (7.04e-2)" "unprognostic (6.37e-2)" "unprognostic (1.67e-2)" "unprognostic (5.61e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (1.84e-1)" "unprognostic (1.99e-3)" "unprognostic (4.43e-1)" "unprognostic (3.53e-3)" "unprognostic (4.90e-2)" "prognostic unfavorable (3.74e-4)" "unprognostic (5.69e-2)" "unprognostic (2.08e-1)" "unprognostic (2.43e-1)" "unprognostic (5.55e-2)" 33.2 29.8 30.1 48.7 31.4 25.8 39.2 35.7 44.3 37.9 31.6 34.9 24.7 52.5 37.0 35.1 45.9 32.0 36.0 27.9 33.7 30.8 41.7 31.9 65.3 28.9 30.5 58.9 26.2 38.5 22.0 52.1 30.4 34.2 42.0 52.0 19.9 34.9 37.5 34.2 33.2 48.6 30.9 43.4 31.9 54.5 32.8 73.6 38.8 47.2 60.9 38.6 22.4 38.9 169.1 152.9 194.1 135.8 91.4 107.9 145.5 166.6 109.2 192.9 151.8 217.3 114.7 256.0 117.4 127.1 186.3 125.0 307.9 126.5 268.6 151.6 110.7 242.8 136.2 148.4 55.4 234.6 145.4 62.9 103.8 149.4 145.9 126.0 149.5 108.7 285.5 127.7 164.9 97.8 212.6 100.4 213.1 189.9 111.5 175.6 208.0 148.1 103.0 124.9 152.8 77.5 174.2 142.8 87.1 185.6 108.6 110.8 98.9 153.7 178.7 137.2 175.0 102.8 203.2 347.0 96.8 214.0 151.0 3.3 1.4 2.2 1.8 2.2 1.9 1.1 1.0 1.8 2.1 0.7 1.0 1.0 0.6 2.7 1.2 1.6 1.2 1.2 30.1 31.4 35.7 44.3 27.9 33.7 28.9 30.5 30.4 30.9 32.8 38.9 42.0 41.7 43.2 114.3 55.3 52.1 32.1 45.5 78.6 67.5 40.2 38.6 64.5 38.6 38.7 31.3 95.9 54.1 56.6 27.3 13.7 29.7 4.2 58.6 79.7 47.7 45.1 73.2 87.9 26.1 49.3 49.9 42.3 68.6 41.8 100.4 41.4 55.8 57.2 72.3 101.3 34.2 40.7 55.3 58.4 11.9 33.5 63.9 37.4 68.4 64.2 33.4 61.8 83.4 102.5 32.3 20.9 30.9 57.2 55.6 21.0 22.2 56.9 101.7 19.7 50.5 55.7 65.9 91.6 83.3 56.8 30.1 54.5 54.4 46.2 47.7 XRCC2 FANCU ENSG00000196584 "X-ray repair cross complementing 2" O43543 7 152644776-152676141 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Fanconi anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 5.3" "Cell type enhanced" "Detected in many" "Erythroid cells: 14.1;Extravillous trophoblasts: 21.2;Granulosa cells: 20.2;Spermatocytes: 31.3;Spermatogonia: 19.1;Syncytiotrophoblasts: 12.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065153 Approved Nucleoplasm,Vesicles NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Vesicles" "HPA065153: AB_2685422" "unprognostic (9.31e-3)" "unprognostic (8.25e-2)" "unprognostic (1.62e-1)" "unprognostic (5.53e-3)" "unprognostic (9.10e-2)" "unprognostic (2.52e-2)" "unprognostic (3.36e-5)" "unprognostic (9.98e-3)" "unprognostic (5.82e-3)" "unprognostic (4.04e-3)" "unprognostic (1.06e-3)" "unprognostic (2.43e-2)" "unprognostic (1.55e-15)" "unprognostic (4.52e-3)" "unprognostic (3.01e-1)" "unprognostic (5.14e-1)" "unprognostic (1.73e-2)" 0.2 0.2 0.9 2.3 0.6 5.3 1.5 1.6 2.8 0.3 0.0 1.1 1.7 1.1 0.9 1.0 0.5 0.4 1.0 0.6 1.9 0.4 0.4 0.5 2.9 0.6 0.6 1.0 0.0 0.6 0.0 2.1 1.4 0.7 1.7 1.9 0.2 0.4 0.1 1.9 1.5 0.5 1.1 1.0 1.0 3.0 1.0 3.6 0.6 0.0 2.5 0.5 0.1 1.9 16.5 10.4 18.3 15.8 1.1 1.8 15.0 11.8 3.9 8.2 10.3 14.7 12.8 24.8 9.5 3.5 13.7 13.7 12.8 7.1 19.3 8.9 17.3 16.8 15.5 10.0 0.3 27.3 9.3 0.9 1.1 15.6 3.6 2.0 3.8 15.5 34.2 22.8 8.3 12.6 32.4 21.2 21.6 10.8 12.9 22.8 19.3 15.3 3.1 10.3 16.7 18.1 11.7 7.6 5.0 11.3 5.4 8.3 4.2 17.2 6.9 13.3 23.0 8.8 14.5 19.0 11.0 20.9 20.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.9 0.6 1.6 2.8 0.6 1.9 0.6 0.6 1.4 1.1 1.0 1.9 0.2 0.0 1.1 1.6 1.9 1.3 1.0 1.0 0.0 4.9 0.8 0.4 2.9 0.0 1.4 1.8 0.0 11.2 0.4 0.9 0.0 1.1 11.7 0.9 1.9 1.1 0.0 14.1 2.3 0.2 21.2 2.5 3.1 1.4 0.0 20.2 1.1 0.2 2.4 0.0 2.0 1.7 2.0 0.6 0.8 4.9 0.9 0.8 0.0 0.0 0.6 1.1 3.1 4.5 2.0 0.5 0.1 1.2 6.1 0.6 0.3 0.3 0.1 2.3 0.0 1.9 1.8 31.3 19.1 2.7 1.4 12.6 2.2 1.2 2.3 1.0 YBX1 "BP-8, CSDA2, CSDB, DBPB, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1" ENSG00000065978 "Y-box binding protein 1" P67809 1 42682418-42703805 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Mitogen, Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2038.9" "Cell type enhanced" "Detected in all" "Early spermatids: 8388.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005875, HPA040304, HPA057159" Supported Supported "Endoplasmic reticulum,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 1600000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 43: THP-1 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Endoplasmic reticulum, Vesicles, Plasma membrane" "CAB005875: AB_2219278, HPA040304: AB_10795364, HPA057159: AB_2683355" "unprognostic (8.59e-2)" "unprognostic (5.16e-2)" "unprognostic (9.27e-3)" "unprognostic (2.68e-3)" "unprognostic (7.76e-2)" "unprognostic (8.03e-3)" "prognostic unfavorable (9.87e-10)" "unprognostic (2.80e-2)" "unprognostic (2.31e-2)" "unprognostic (2.79e-3)" "unprognostic (7.51e-2)" "unprognostic (5.52e-2)" "prognostic unfavorable (3.59e-7)" "unprognostic (3.66e-2)" "unprognostic (2.44e-1)" "unprognostic (1.94e-2)" "unprognostic (3.25e-1)" 532.0 254.5 141.7 422.4 155.4 863.9 401.1 153.3 157.7 331.8 154.4 600.2 364.9 406.2 211.3 365.0 337.0 209.8 789.7 140.6 159.4 318.9 309.9 396.3 407.9 175.1 160.2 311.7 266.7 133.8 122.2 242.2 178.8 307.8 378.1 391.8 270.5 219.5 2038.9 295.0 366.1 338.9 152.7 367.1 405.0 783.5 180.8 353.4 282.0 1133.9 382.2 501.5 332.3 173.5 1552.8 761.5 1020.4 1232.7 991.0 908.1 1200.2 971.5 768.9 1116.6 875.8 1034.6 1253.7 1630.6 1157.5 825.2 495.5 870.2 1162.6 1230.5 1103.9 1087.8 1278.0 1596.4 1491.9 1343.8 786.7 2214.4 1320.7 812.6 1092.3 1094.5 1365.7 630.0 950.3 1271.9 1823.0 720.6 1104.0 837.7 2816.5 2464.6 2902.1 755.0 1006.4 1789.6 1972.5 1938.2 1176.7 933.8 1731.6 1298.5 893.7 1294.0 2038.3 1096.8 443.2 5002.2 862.6 945.4 1748.6 1371.1 2209.3 1213.7 1670.6 2004.8 910.4 1750.3 1049.9 15.3 48.4 69.9 42.9 107.1 52.9 69.4 51.8 43.3 77.4 61.2 44.0 45.9 9.0 35.1 124.2 58.6 69.7 34.1 141.7 155.4 153.3 157.7 140.6 159.4 175.1 160.2 178.8 152.7 180.8 173.5 701.7 173.1 230.9 16.3 818.3 1397.7 1265.9 419.7 747.3 247.8 569.7 564.5 1072.3 441.8 355.5 325.5 150.1 753.9 678.4 620.6 1457.6 1013.6 8388.7 363.5 695.5 755.1 587.8 2244.2 16.2 886.6 1998.9 687.6 461.3 427.0 383.1 489.1 483.3 480.1 1708.7 121.1 27.1 930.2 354.0 1656.0 2342.9 3743.4 751.2 1307.6 905.4 19.7 1171.0 463.8 744.6 23.6 32.7 858.2 975.1 806.1 981.0 1935.1 993.3 1169.8 196.2 602.4 466.8 754.8 1083.7 3245.2 425.5 1113.5 1302.5 481.5 635.6 811.4 1257.7 1697.8 YIF1A "54TM, FinGER7, YIF1, YIF1P" ENSG00000174851 "Yip1 interacting factor homolog A, membrane trafficking protein" O95070 11 66284580-66289145 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014840, HPA076194" Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Golgi apparatus, Vesicles" "HPA014840: AB_2217189, HPA076194: " "unprognostic (9.35e-2)" "unprognostic (7.86e-2)" "unprognostic (1.37e-1)" "unprognostic (1.94e-1)" "unprognostic (3.23e-1)" "unprognostic (4.38e-3)" "unprognostic (2.25e-3)" "unprognostic (2.51e-2)" "unprognostic (3.57e-2)" "unprognostic (2.13e-1)" "unprognostic (6.39e-3)" "unprognostic (1.35e-1)" "unprognostic (2.60e-2)" "unprognostic (2.03e-1)" "unprognostic (2.64e-1)" "unprognostic (6.53e-2)" "prognostic unfavorable (8.70e-4)" 49.2 54.7 33.4 28.4 36.0 16.7 47.5 38.5 41.4 42.7 42.4 50.8 56.5 53.5 34.5 50.9 45.7 25.5 57.8 33.5 35.6 50.9 149.5 44.9 22.9 38.9 36.1 42.1 86.0 40.6 74.1 34.5 38.2 47.3 37.7 12.3 51.1 29.6 96.2 43.0 47.4 41.1 38.5 35.9 56.1 36.4 35.6 21.6 49.9 59.3 24.7 45.4 40.6 41.9 80.7 131.3 39.4 72.6 130.0 138.7 73.8 114.4 122.3 95.5 94.3 126.0 95.5 67.9 111.5 161.4 107.8 119.9 60.7 107.9 75.6 77.7 72.0 42.5 93.3 158.7 147.4 59.3 61.5 97.4 144.4 98.6 158.9 76.6 91.3 67.0 80.7 114.8 84.3 199.3 71.3 64.4 40.3 147.4 136.6 54.9 61.2 203.9 81.9 70.9 58.5 57.9 62.5 106.7 103.4 49.6 155.5 43.5 81.0 80.8 69.0 165.3 54.1 78.1 86.0 63.0 125.4 56.2 90.2 19.4 95.6 20.6 71.3 141.4 78.4 95.9 60.6 67.2 116.4 82.4 48.0 55.3 9.4 51.2 140.0 141.6 54.9 99.8 33.4 36.0 38.5 41.4 33.5 35.6 38.9 36.1 38.2 38.5 35.6 41.9 63.4 38.5 48.0 6.2 52.2 36.1 88.1 170.4 38.1 27.1 84.4 92.7 34.5 82.9 115.5 46.0 22.9 114.3 42.6 66.8 64.6 137.9 28.1 42.1 84.8 53.6 87.4 21.0 1.9 149.4 248.5 90.4 55.0 42.8 29.9 38.8 49.2 172.0 105.4 26.9 3.9 140.9 116.0 38.4 44.9 48.6 75.5 45.0 72.9 8.4 40.8 73.7 28.8 10.1 10.4 132.1 93.3 82.4 92.4 195.2 202.2 135.2 101.4 34.0 39.5 60.8 150.0 61.0 56.8 63.3 46.3 154.3 36.5 88.1 107.2 112.1 YIF1B FinGER8 ENSG00000167645 "Yip1 interacting factor homolog B, membrane trafficking protein" Q5BJH7 19 38303558-38317273 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 94.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039328, HPA055257, HPA062675" Approved Approved "Golgi apparatus,Vesicles" NA NA 37000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" Vesicles "Golgi apparatus" "HPA039328: AB_2676445, HPA055257: AB_2682762, HPA062675: AB_2684830" "unprognostic (2.51e-1)" "unprognostic (3.34e-1)" "unprognostic (1.38e-1)" "unprognostic (6.81e-2)" "unprognostic (1.45e-1)" "unprognostic (2.74e-1)" "prognostic unfavorable (4.53e-5)" "unprognostic (1.37e-1)" "unprognostic (1.45e-2)" "unprognostic (5.53e-2)" "prognostic favorable (1.88e-4)" "unprognostic (4.57e-2)" "unprognostic (2.40e-2)" "unprognostic (3.69e-1)" "unprognostic (1.26e-1)" "unprognostic (2.64e-1)" "unprognostic (3.94e-3)" 30.1 30.7 29.3 33.0 32.4 69.1 26.7 37.0 38.3 33.5 29.0 26.6 20.4 24.1 10.9 33.2 25.6 16.5 40.6 30.2 32.6 27.2 58.3 35.7 32.1 36.3 30.9 26.7 27.1 16.9 29.1 23.5 38.6 23.7 16.1 13.6 30.2 12.5 35.0 26.0 24.0 18.1 33.4 47.7 22.0 23.1 34.0 20.9 19.8 26.7 20.9 26.8 25.6 38.5 43.7 108.9 48.3 57.5 68.4 63.5 37.8 103.2 79.0 75.7 110.7 53.5 32.6 75.7 44.4 121.1 81.5 27.4 85.9 54.6 28.7 81.1 43.3 117.0 48.2 56.5 94.8 82.4 132.9 52.3 47.9 78.0 33.8 76.1 71.3 99.4 152.9 205.3 68.5 46.0 87.6 98.9 37.0 74.9 33.7 89.0 58.6 117.9 48.9 40.6 34.8 58.1 34.5 76.7 55.4 37.2 29.9 163.2 68.8 74.6 73.2 108.4 83.9 76.4 122.1 51.8 96.1 150.5 54.6 81.9 155.7 179.0 60.8 119.4 54.4 49.3 57.3 54.8 300.3 42.7 46.7 47.5 42.8 44.0 70.8 127.0 59.0 120.2 29.3 32.4 37.0 38.3 30.2 32.6 36.3 30.9 38.6 33.4 34.0 38.5 27.4 0.0 5.5 5.5 22.8 17.7 19.4 25.8 18.2 12.2 22.6 18.7 4.7 18.6 14.2 22.0 12.5 44.7 17.0 16.0 0.0 39.4 6.3 17.5 18.2 23.9 14.4 33.2 7.3 27.7 52.9 23.8 16.3 18.6 22.9 43.4 37.1 30.5 94.4 11.8 7.4 24.7 32.6 42.3 37.4 8.5 9.0 53.3 35.6 3.7 34.4 20.8 16.5 4.0 12.7 15.5 13.5 9.1 69.4 14.8 8.1 16.1 20.7 15.5 6.6 11.1 40.3 20.6 31.9 30.7 20.0 27.6 18.8 26.2 25.9 19.5 YIPF4 "FinGER4, MGC11061" ENSG00000119820 "Yip1 domain family member 4" Q9BSR8 2 32277904-32316594 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "brain: 129.1;choroid plexus: 65.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017884 Supported Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" "Vesicles, Plasma membrane" "HPA017884: AB_1853855" "unprognostic (5.61e-3)" "unprognostic (8.50e-2)" "unprognostic (3.88e-2)" "unprognostic (3.17e-3)" "unprognostic (3.05e-1)" "unprognostic (7.64e-2)" "unprognostic (3.45e-2)" "unprognostic (3.61e-2)" "unprognostic (3.69e-1)" "unprognostic (8.70e-2)" "unprognostic (4.15e-1)" "unprognostic (1.54e-1)" "unprognostic (2.29e-3)" "unprognostic (1.90e-1)" "unprognostic (1.59e-1)" "unprognostic (3.88e-2)" "unprognostic (6.11e-2)" 7.0 6.2 69.9 5.5 66.9 2.5 8.4 69.6 129.1 6.1 65.6 6.9 5.8 6.9 7.2 5.0 5.0 4.5 7.4 71.7 68.8 7.7 9.2 5.6 5.9 69.3 67.7 6.6 14.8 6.5 5.2 5.9 71.9 6.6 6.2 13.1 7.4 5.6 8.0 7.0 5.8 6.5 66.8 6.9 6.4 4.2 67.3 7.9 10.1 6.0 5.1 5.3 5.1 75.4 8.9 4.4 8.6 7.7 9.8 12.4 4.5 7.5 7.5 7.7 5.0 5.9 6.6 4.7 5.1 8.2 7.4 6.8 9.2 6.6 10.0 7.6 14.3 7.6 9.8 10.7 11.5 10.2 6.2 8.7 12.4 6.9 11.0 10.6 6.6 5.2 10.7 9.6 8.5 5.8 8.0 10.6 7.0 9.6 7.5 5.5 12.7 8.9 8.4 3.8 9.6 9.2 6.4 6.4 11.7 5.5 3.5 8.6 7.4 10.1 4.8 7.1 7.2 14.2 19.1 5.8 15.9 9.7 5.7 14.9 5.4 5.7 4.4 5.1 3.7 4.6 4.4 4.1 4.6 4.0 4.5 4.0 14.9 6.4 5.1 5.4 4.6 4.7 69.9 66.9 69.6 129.1 71.7 68.8 69.3 67.7 71.9 66.8 67.3 75.4 61.4 93.0 69.8 13.1 68.5 51.4 56.9 59.5 50.7 113.8 63.3 28.2 88.0 60.1 58.3 42.3 106.3 68.4 81.3 68.8 33.2 45.3 34.7 39.5 57.9 59.0 57.1 86.9 18.8 39.3 69.9 66.6 28.1 40.1 40.0 56.3 67.8 80.9 48.3 101.0 20.1 70.2 50.8 81.7 60.7 21.0 86.6 58.0 81.8 21.5 85.1 53.1 114.4 22.1 31.8 41.8 66.8 74.9 62.6 78.5 62.7 60.1 62.2 122.2 78.9 71.9 66.2 160.2 59.6 41.1 65.9 192.8 60.7 65.4 46.8 74.7 YIPF5 "FinGER5, SMAP-5" ENSG00000145817 "Yip1 domain family member 5" Q969M3 5 144158162-144170714 "Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 236.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042338, HPA073622" Supported Supported "Nucleoplasm,Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" "Endoplasmic reticulum, Golgi apparatus, Vesicles" Nucleoplasm "HPA042338: AB_2677953, HPA073622: AB_2686618" "prognostic unfavorable (7.83e-5)" "unprognostic (1.13e-3)" "unprognostic (1.95e-2)" "unprognostic (8.35e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (1.12e-5)" "prognostic unfavorable (3.26e-5)" "unprognostic (2.89e-2)" "unprognostic (1.99e-1)" "unprognostic (3.64e-2)" "unprognostic (1.20e-3)" "unprognostic (4.79e-2)" "unprognostic (8.79e-2)" "unprognostic (1.69e-1)" "unprognostic (1.24e-2)" "unprognostic (5.11e-2)" "unprognostic (6.49e-2)" 22.2 20.4 8.3 17.7 9.8 21.0 24.1 9.8 11.0 24.7 16.3 25.8 30.5 20.2 21.2 28.6 20.3 21.4 18.1 9.5 12.5 25.4 31.7 20.3 18.9 9.7 10.3 20.6 32.0 25.7 17.0 30.2 11.5 18.3 26.0 20.6 26.2 19.2 9.3 17.7 27.3 28.5 10.3 15.5 22.7 20.9 10.3 16.1 22.6 14.5 23.9 24.0 14.3 12.0 43.2 28.2 36.0 28.6 84.4 90.5 32.9 143.6 96.9 63.2 101.5 45.3 44.0 23.5 67.3 156.9 72.5 38.7 34.7 70.5 84.8 32.9 30.2 17.4 44.9 46.7 68.0 39.3 27.7 69.1 64.3 56.8 46.3 108.9 61.0 25.6 18.8 38.5 86.4 22.5 19.4 22.2 23.3 27.5 30.7 20.3 53.4 39.3 39.4 37.7 24.4 30.0 49.7 26.4 66.5 36.2 54.9 25.5 236.7 74.0 35.8 72.5 57.2 34.7 61.8 29.9 70.7 36.9 55.2 48.9 34.5 48.7 47.2 47.4 53.1 37.9 47.1 52.4 41.2 36.4 49.0 46.3 26.0 41.0 44.7 45.0 62.8 40.6 8.3 9.8 9.8 11.0 9.5 12.5 9.7 10.3 11.5 10.3 10.3 12.0 43.5 38.5 27.4 8.5 35.6 29.4 24.5 49.4 26.2 40.6 33.4 29.6 21.8 31.5 35.9 20.2 33.3 56.7 40.5 33.0 31.3 43.7 14.9 31.4 49.8 44.1 14.8 20.0 19.7 68.3 77.1 51.9 33.6 31.2 36.8 34.1 30.4 34.7 36.5 33.7 16.9 50.1 22.4 34.0 24.4 7.3 35.4 28.7 30.2 6.5 38.3 54.9 27.8 13.6 16.2 60.5 35.5 33.8 70.0 23.4 56.0 36.1 50.6 53.8 39.5 31.8 45.4 83.9 56.0 33.4 26.0 67.5 42.0 41.1 27.4 24.5 YIPF6 "FinGER6, MGC21416" ENSG00000181704 "Yip1 domain family member 6" Q96EC8 X 68498562-68537282 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 278.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003720 Uncertain Approved Vesicles NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: U-2197 - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "HPA003720: AB_1080626" "unprognostic (5.07e-3)" "unprognostic (2.13e-1)" "unprognostic (1.53e-1)" "unprognostic (1.72e-1)" "unprognostic (7.17e-2)" "unprognostic (5.90e-3)" "unprognostic (1.64e-1)" "unprognostic (1.28e-1)" "unprognostic (1.75e-1)" "unprognostic (2.15e-1)" "unprognostic (1.33e-2)" "unprognostic (3.15e-1)" "unprognostic (8.85e-3)" "unprognostic (8.48e-2)" "unprognostic (2.90e-2)" "unprognostic (3.25e-1)" "unprognostic (6.32e-2)" 14.3 14.7 13.9 7.8 15.7 6.6 14.9 15.6 15.4 14.5 15.4 12.5 11.7 13.3 14.5 11.6 13.2 11.1 11.6 12.9 16.0 18.9 21.6 12.4 6.4 15.9 16.5 10.5 14.5 20.6 15.0 18.2 14.9 19.9 14.1 14.3 16.4 14.5 16.9 10.7 11.4 12.9 15.1 8.3 15.3 6.2 15.7 6.7 21.8 16.4 7.4 12.4 8.4 15.5 23.5 22.4 22.6 7.9 28.7 17.8 24.8 18.0 22.5 13.8 17.4 23.5 23.5 0.1 32.6 15.1 22.8 18.2 29.8 12.2 23.2 6.8 20.2 10.4 22.6 19.6 26.4 11.4 14.3 17.6 22.3 20.5 25.4 24.1 13.8 13.4 16.6 22.3 18.8 24.8 6.6 9.7 24.0 34.0 23.3 6.7 27.5 12.3 22.9 25.9 23.5 24.6 30.6 20.9 21.7 20.4 12.9 11.8 18.8 15.4 14.8 49.2 35.0 12.2 15.0 4.6 22.8 17.2 26.1 5.3 4.0 4.7 2.2 4.7 1.5 3.9 2.2 2.0 3.0 2.1 2.2 1.9 10.5 2.9 4.2 3.6 2.6 2.8 13.9 15.7 15.6 15.4 12.9 16.0 15.9 16.5 14.9 15.1 15.7 15.5 42.1 70.5 99.6 25.5 25.6 34.9 62.3 110.0 21.6 54.6 47.4 32.3 33.7 32.9 88.6 57.0 47.9 101.6 19.8 43.8 35.2 47.4 25.9 50.9 35.2 41.7 54.4 80.4 18.8 43.9 111.3 53.1 27.5 47.8 53.7 33.6 42.1 60.2 44.1 45.4 21.9 61.8 93.6 25.9 42.0 63.2 42.6 38.5 35.6 23.4 23.4 63.5 29.9 26.7 34.9 47.3 34.7 47.4 42.7 90.4 42.4 62.4 81.6 52.7 26.3 50.8 44.6 31.5 28.1 31.4 43.3 278.8 29.0 29.6 33.5 89.5 YY1 "DELTA, INO80S, NF-E1, UCRBP, YIN-YANG-1" ENSG00000100811 "YY1 transcription factor" P25490 14 100238298-100282788 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, DNA damage, DNA recombination, DNA repair, Spermatogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001119, CAB009392" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Nucleoli fibrillar center, Vesicles" "CAB009392: AB_2218501, HPA001119: AB_1858930" "unprognostic (7.67e-2)" "unprognostic (8.08e-2)" "unprognostic (2.57e-2)" "prognostic unfavorable (6.13e-4)" "unprognostic (6.75e-3)" "unprognostic (8.31e-3)" "prognostic unfavorable (3.44e-4)" "unprognostic (1.09e-1)" "unprognostic (4.26e-2)" "unprognostic (7.68e-3)" "unprognostic (1.40e-1)" "unprognostic (1.51e-1)" "unprognostic (3.72e-2)" "unprognostic (4.36e-2)" "unprognostic (1.66e-1)" "unprognostic (2.30e-1)" "unprognostic (4.30e-1)" 27.2 26.2 20.9 28.9 22.1 56.4 27.0 27.0 24.2 24.6 18.5 30.7 27.9 24.8 34.0 28.9 21.7 22.7 22.8 22.7 20.2 32.9 46.8 24.0 36.0 20.4 20.4 21.6 24.4 32.5 17.4 34.2 20.3 25.2 28.7 20.1 25.1 23.6 36.8 29.0 29.7 24.8 20.1 31.9 26.2 23.8 21.5 52.3 37.2 27.2 38.2 31.9 21.0 26.2 62.0 30.7 64.2 51.5 51.8 65.9 68.1 60.0 55.1 64.7 66.0 38.6 97.7 94.0 82.3 54.5 37.1 64.0 72.6 64.1 88.3 70.8 60.9 86.8 34.6 50.0 48.4 103.8 73.2 38.7 76.4 45.4 61.4 58.6 63.9 67.3 69.9 61.8 63.7 74.5 113.5 61.8 68.7 98.0 56.0 93.9 88.9 50.7 75.8 58.3 68.2 53.3 79.2 57.8 85.1 54.0 86.6 100.1 57.4 39.4 48.3 97.6 53.8 68.3 72.0 126.6 56.4 68.6 52.5 4.8 5.7 11.9 4.3 4.8 5.6 5.3 5.7 5.9 4.9 8.3 5.4 5.4 9.8 9.5 3.8 5.3 7.7 2.7 20.9 22.1 27.0 24.2 22.7 20.2 20.4 20.4 20.3 20.1 21.5 26.2 116.0 54.5 66.8 23.8 102.4 238.0 101.1 49.9 211.7 80.5 129.8 98.2 91.5 92.9 50.0 68.0 81.3 118.6 147.4 122.8 72.4 68.7 10.3 118.7 133.8 115.7 110.1 125.4 28.2 82.0 123.6 106.7 58.1 153.6 71.7 99.4 103.5 119.4 81.3 127.9 26.5 108.8 48.8 111.8 225.8 15.7 94.8 121.6 76.5 30.0 117.8 82.0 114.4 20.6 40.7 80.0 95.5 100.8 125.0 168.9 90.0 104.6 47.6 74.9 92.1 106.5 124.3 86.0 67.0 192.1 243.1 175.5 124.8 124.1 118.7 153.5 ZADH2 MGC45594 ENSG00000180011 "Zinc binding alcohol dehydrogenase domain containing 2" Q8N4Q0 18 75195113-75209139 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021468, HPA053646" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 33: Fibroblasts - ECM organization" Vesicles "Nucleoplasm, Golgi apparatus" "HPA021468: AB_1858932, HPA053646: AB_2682216" "unprognostic (3.22e-2)" "unprognostic (1.03e-2)" "unprognostic (7.14e-2)" "unprognostic (1.13e-1)" "unprognostic (4.79e-1)" "unprognostic (5.11e-3)" "unprognostic (1.15e-1)" "unprognostic (1.49e-1)" "unprognostic (3.62e-3)" "unprognostic (1.42e-1)" "unprognostic (3.05e-2)" "unprognostic (1.48e-1)" "prognostic favorable (1.02e-6)" "unprognostic (3.41e-1)" "unprognostic (1.87e-1)" "prognostic unfavorable (1.94e-4)" "unprognostic (2.23e-1)" 17.7 12.9 15.6 11.8 17.8 20.7 22.2 19.2 22.0 18.8 14.0 26.3 19.0 15.5 24.8 20.0 17.9 15.8 34.3 17.0 12.9 24.2 32.5 16.3 19.3 16.8 13.9 23.9 26.6 24.7 21.5 36.6 18.3 17.1 28.7 30.6 23.8 18.2 44.9 22.0 26.0 15.2 16.5 16.1 21.3 7.0 15.5 23.3 27.8 40.7 20.6 16.6 16.9 16.8 21.7 14.1 14.8 30.4 22.6 29.0 16.3 38.5 44.6 14.8 18.5 8.7 30.0 15.2 6.0 38.3 17.4 28.7 18.5 32.6 10.4 94.6 27.1 34.1 32.7 17.0 16.0 58.0 33.2 32.2 31.9 11.9 27.2 27.5 30.9 35.2 18.6 54.0 28.6 25.5 14.6 28.6 3.8 20.9 31.9 31.0 23.7 50.2 28.9 36.2 27.2 22.4 21.4 21.7 24.5 10.4 21.8 28.4 27.7 28.9 22.0 9.2 12.4 8.8 41.2 10.5 19.1 49.5 23.8 1.7 3.4 8.9 3.2 2.9 2.3 2.1 2.6 2.9 2.3 1.5 1.4 2.2 1.7 1.7 3.8 1.7 3.2 1.8 15.6 17.8 19.2 22.0 17.0 12.9 16.8 13.9 18.3 16.5 15.5 16.8 41.5 35.3 17.9 12.4 7.5 9.7 18.7 13.9 9.6 59.0 15.3 10.8 56.3 20.0 12.5 27.6 6.2 8.4 15.9 24.8 19.6 12.3 0.5 8.5 39.0 24.1 23.4 9.9 16.6 21.1 8.1 26.4 12.8 11.1 7.0 42.6 23.6 25.0 16.4 25.2 14.1 25.1 14.2 20.2 19.1 2.1 36.7 18.3 12.4 12.2 23.9 21.3 13.4 20.6 14.9 15.5 21.9 63.2 6.2 18.5 35.2 19.0 8.1 40.9 19.7 25.5 12.3 0.4 4.9 23.7 11.1 6.7 11.0 73.0 27.2 20.9 ZBED6CL C7orf29 ENSG00000188707 "ZBED6 C-terminal like" Q96FA7 7 150322639-150332721 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 72.3;parathyroid gland: 25.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 8.4;Exocrine glandular cells: 13.3;Pancreatic endocrine cells: 13.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 85.2;K-562: 34.5" "Low region specificity" "Detected in all" "HPA019724, HPA055805" Approved Approved "Nuclear membrane,Vesicles" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 17: Adrenal gland - Steroid metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 1: Pancreatic cells - Digestion" "Nuclear membrane" Vesicles "HPA019724: AB_1845756, HPA055805: AB_2682929" "prognostic favorable (9.48e-5)" "unprognostic (6.77e-2)" "unprognostic (2.06e-2)" "unprognostic (7.41e-2)" "prognostic unfavorable (3.12e-5)" "unprognostic (3.35e-2)" "unprognostic (2.49e-3)" "unprognostic (2.78e-2)" "unprognostic (3.12e-2)" "unprognostic (3.44e-1)" "prognostic favorable (2.44e-5)" "unprognostic (2.78e-1)" "prognostic unfavorable (1.38e-5)" "unprognostic (1.86e-2)" "unprognostic (7.82e-2)" "unprognostic (8.52e-3)" "unprognostic (1.50e-3)" 1.3 72.3 1.0 5.2 0.8 3.8 2.1 0.6 0.8 3.0 3.1 4.0 3.3 4.3 1.2 3.0 4.1 1.6 1.2 1.1 1.1 5.3 12.1 3.1 6.9 1.1 1.0 6.0 7.2 25.6 5.4 0.8 0.8 3.5 3.1 1.7 2.7 2.1 0.5 3.6 5.0 1.8 0.6 4.9 4.2 1.1 1.2 5.6 4.0 0.2 6.7 2.7 2.1 0.6 8.1 0.2 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.3 0.9 10.9 8.4 4.8 4.0 0.1 0.0 3.5 0.0 0.0 0.7 85.2 5.4 6.3 13.3 17.6 2.1 0.0 8.4 1.4 3.9 0.0 0.0 0.3 0.4 16.2 34.5 11.8 0.0 3.3 14.5 2.8 5.3 3.4 0.0 0.0 0.5 10.2 3.2 16.4 15.1 8.4 14.9 3.2 0.5 2.4 1.0 3.6 0.2 0.0 0.0 0.0 0.1 10.0 3.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.7 0.2 0.8 0.5 0.6 0.9 0.2 0.8 0.8 0.8 0.8 0.7 0.0 0.2 0.6 0.7 1.0 0.8 0.6 0.8 1.1 1.1 1.1 1.0 0.8 0.6 1.2 0.6 0.0 0.0 1.5 0.0 0.6 0.3 0.5 1.0 0.0 1.0 1.2 0.9 0.9 2.8 1.6 1.8 8.4 1.5 2.2 2.2 5.9 2.8 0.0 3.1 0.4 0.9 4.8 0.8 0.0 13.3 0.8 0.6 1.5 3.3 1.3 1.3 0.4 3.7 0.6 0.0 0.0 2.4 4.1 1.2 0.0 0.4 2.8 0.7 0.0 0.0 3.4 1.2 3.1 0.0 0.0 13.4 1.2 1.2 0.2 0.4 1.3 0.9 0.6 0.6 0.0 0.9 0.2 0.4 0.9 0.9 0.1 1.9 1.4 1.1 2.3 0.4 ZBTB39 "KIAA0352, ZNF922" ENSG00000166860 "Zinc finger and BTB domain containing 39" O15060 12 56998836-57006546 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 16.7;Early spermatids: 19.9;Horizontal cells: 21.9;Late spermatids: 20.3;Spermatogonia: 17.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "RH-30: 46.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016866, HPA020306" Uncertain Approved Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Vesicles "HPA016866: AB_2669470, HPA020306: AB_2670406" "unprognostic (2.06e-2)" "unprognostic (1.61e-1)" "unprognostic (8.92e-2)" "unprognostic (2.90e-2)" "unprognostic (3.07e-1)" "unprognostic (2.68e-2)" "unprognostic (4.10e-3)" "unprognostic (1.69e-1)" "unprognostic (1.70e-2)" "unprognostic (1.59e-1)" "unprognostic (1.22e-3)" "unprognostic (1.76e-1)" "unprognostic (2.34e-1)" "unprognostic (5.74e-2)" "unprognostic (3.46e-1)" "unprognostic (2.54e-2)" "unprognostic (7.00e-2)" 2.6 1.5 1.7 2.9 2.0 5.8 2.8 2.2 2.0 2.1 0.9 2.5 2.2 3.2 2.5 2.4 3.1 1.8 2.2 1.6 1.8 2.1 3.4 2.7 3.9 1.9 2.0 4.4 2.9 3.3 1.1 3.7 1.9 2.6 2.3 2.9 2.6 3.3 2.5 2.9 2.9 2.8 1.5 4.2 2.6 7.1 2.0 4.2 2.5 2.7 3.6 2.1 1.7 2.3 3.4 5.5 15.3 7.9 3.4 3.6 10.1 3.2 4.1 5.2 3.7 5.7 2.3 10.8 4.2 3.2 3.3 4.5 11.8 5.0 5.0 5.0 8.2 12.1 3.6 4.6 3.2 9.3 9.6 2.8 4.8 4.1 6.6 5.6 6.0 12.2 15.2 9.7 3.8 3.9 13.7 7.8 15.2 3.5 4.6 13.0 46.9 5.2 2.4 6.7 7.5 9.7 4.7 6.0 4.7 14.2 5.1 10.1 4.8 4.3 9.5 2.0 4.1 12.5 8.7 11.5 2.7 5.2 2.7 0.7 0.3 0.0 0.4 0.2 0.4 0.3 0.4 0.6 0.4 0.4 0.3 0.6 0.0 0.7 0.0 0.5 0.1 0.3 1.7 2.0 2.2 2.0 1.6 1.8 1.9 2.0 1.9 1.5 2.0 2.3 2.9 0.0 0.6 3.3 3.5 1.5 2.3 1.6 7.4 11.6 1.7 1.5 3.5 2.8 1.9 0.0 16.7 3.1 3.0 0.9 0.0 1.5 19.9 1.2 3.3 4.3 1.2 2.1 1.8 1.8 1.8 2.3 1.5 1.2 1.3 3.6 8.6 2.5 1.9 21.9 1.8 2.5 2.0 3.0 2.0 20.3 1.8 1.4 1.8 0.0 3.6 1.8 3.1 1.5 2.8 2.5 3.2 5.7 3.2 3.5 1.5 1.4 3.1 7.4 6.6 3.4 2.2 10.1 17.6 3.2 1.6 2.2 2.1 1.9 2.4 1.4 ZC3H10 "FLJ14451, ZC3HDC10" ENSG00000135482 "Zinc finger CCCH-type containing 10" Q96K80 12 56118260-56127514 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 47.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039236, HPA062265" Uncertain Approved Vesicles NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" Vesicles "HPA039236: AB_10795463, HPA062265: AB_2684730" "unprognostic (1.19e-1)" "unprognostic (1.53e-1)" "unprognostic (2.97e-1)" "unprognostic (7.39e-2)" "unprognostic (2.27e-1)" "unprognostic (3.35e-2)" "unprognostic (2.95e-2)" "unprognostic (1.53e-2)" "unprognostic (2.07e-2)" "unprognostic (2.80e-1)" "unprognostic (1.31e-5)" "unprognostic (4.42e-2)" "unprognostic (2.69e-2)" "unprognostic (6.45e-2)" "unprognostic (1.40e-1)" "unprognostic (2.58e-2)" "unprognostic (1.21e-1)" 2.8 3.1 1.9 3.0 2.8 1.4 2.5 3.4 2.4 3.8 1.1 3.6 1.6 3.9 2.2 1.9 3.3 1.7 2.5 1.9 2.1 2.3 2.9 2.4 2.9 2.9 2.5 4.1 3.6 2.5 2.4 2.0 2.7 2.6 1.3 4.0 2.8 2.4 5.0 2.4 2.3 2.0 2.1 3.9 2.4 8.7 2.7 2.9 2.6 3.1 2.2 3.3 2.6 4.0 3.3 5.8 4.6 3.6 5.5 3.7 3.5 3.9 2.6 2.3 1.8 1.6 1.9 3.7 6.3 2.8 1.3 4.4 2.4 1.4 1.5 6.3 6.1 5.5 5.8 1.7 3.4 5.4 3.3 2.4 3.1 2.7 3.1 4.3 3.5 4.2 2.9 6.5 3.1 2.4 5.6 2.1 3.1 1.9 4.7 5.5 5.0 3.4 1.9 1.6 4.4 4.3 2.3 3.4 3.5 3.4 5.6 4.5 5.0 2.2 5.1 4.3 2.9 5.4 3.7 2.0 2.9 2.4 5.4 3.6 5.0 5.9 4.7 6.0 4.9 3.6 3.7 4.1 5.3 3.9 3.7 3.6 3.6 8.0 10.5 2.4 2.0 3.7 1.9 2.8 3.4 2.4 1.9 2.1 2.9 2.5 2.7 2.1 2.7 4.0 4.2 0.0 4.2 1.3 5.6 0.8 2.5 1.3 1.8 9.0 3.2 2.2 3.0 5.7 0.8 7.3 20.9 6.3 5.9 7.1 15.6 5.3 47.6 2.2 4.3 5.1 1.2 5.2 0.6 3.0 2.7 3.3 1.1 2.6 2.5 5.9 6.8 3.0 5.3 13.5 0.9 3.8 2.0 7.4 1.6 9.5 5.3 4.0 3.6 1.0 10.6 9.2 9.2 0.0 1.5 3.3 2.3 5.3 1.6 2.3 6.0 4.7 2.7 17.3 0.0 6.2 5.3 16.2 15.5 1.9 1.7 6.4 3.2 5.1 3.9 1.4 ZC3H12B "CXorf32, MCPIP2" ENSG00000102053 "Zinc finger CCCH-type containing 12B" Q5HYM0 X 65366638-65507887 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 30 "Astrocytes: 90.4;Excitatory neurons: 232.1;Inhibitory neurons: 219.8;Microglial cells: 128.4;Oligodendrocyte precursor cells: 253.8;Oligodendrocytes: 258.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA000836 Uncertain Approved "Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Endoplasmic reticulum" "Golgi apparatus, Vesicles" "HPA000836: AB_2217374" "unprognostic (1.91e-1)" "unprognostic (9.72e-2)" "unprognostic (1.38e-1)" "unprognostic (1.71e-2)" "unprognostic (1.64e-1)" "unprognostic (7.44e-3)" "unprognostic (7.86e-3)" "unprognostic (5.46e-2)" "unprognostic (3.32e-1)" "unprognostic (5.76e-2)" "unprognostic (1.12e-3)" "unprognostic (1.28e-1)" "unprognostic (2.61e-1)" "unprognostic (1.11e-2)" "unprognostic (5.08e-2)" "unprognostic (1.45e-2)" "unprognostic (1.71e-2)" 0.6 0.5 2.4 0.4 2.7 0.2 0.5 2.1 2.7 1.3 0.8 1.3 0.6 1.3 0.5 0.3 1.3 0.6 0.6 2.7 1.6 0.7 0.5 0.5 0.5 1.1 1.4 1.7 0.4 1.6 2.2 0.0 0.9 1.1 0.6 1.9 0.6 1.1 0.2 0.3 0.9 0.9 1.3 0.4 0.8 0.2 2.1 0.9 1.0 0.3 0.3 1.0 0.9 2.3 0.1 0.2 2.1 0.3 0.0 0.0 0.2 0.5 1.1 0.0 0.3 0.2 0.2 0.3 0.1 0.6 0.0 0.3 0.5 0.0 0.0 0.3 1.5 0.7 1.2 0.3 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.4 0.0 1.7 0.4 1.7 0.0 0.0 0.9 0.2 0.8 1.2 0.4 1.0 0.1 0.4 0.0 0.1 0.0 1.0 0.0 0.0 0.0 1.2 0.0 0.5 0.0 0.0 0.4 0.7 0.2 0.3 0.4 0.7 1.3 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 2.4 2.7 2.1 2.7 2.7 1.6 1.1 1.4 0.9 1.3 2.1 2.3 0.2 6.4 0.5 90.4 1.3 0.0 0.5 0.0 1.2 2.7 0.1 0.6 0.6 0.0 0.0 0.0 2.1 0.0 0.1 0.7 0.0 0.2 0.2 0.7 1.3 0.5 4.2 0.0 232.1 0.2 0.2 1.4 0.0 0.1 0.0 0.6 0.7 0.7 0.1 1.7 219.8 1.3 0.0 0.0 0.3 0.2 2.5 0.0 0.0 128.4 0.1 1.0 0.0 253.8 258.0 0.2 0.6 4.1 0.3 0.3 1.0 0.4 0.0 1.5 0.0 2.1 1.1 0.0 0.1 0.1 0.4 0.0 0.4 0.5 1.0 0.1 ZC4H2 "HCA127, KIAA1166, MCS, MRXS4, WWS" ENSG00000126970 "Zinc finger C4H2-type containing" Q9NQZ6 X 64915802-65034713 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 37.4;Inhibitory neurons: 39.4;Oligodendrocyte precursor cells: 58.3;Oligodendrocytes: 59.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NTERA-2: 37.3;REH: 29.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049584 Approved Approved Vesicles,Microtubules NA NA "Cluster 30: Non-specific - Translation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Microtubules" "HPA049584: AB_2680825" "unprognostic (9.55e-3)" "unprognostic (1.03e-1)" "unprognostic (4.40e-1)" "unprognostic (1.56e-1)" "unprognostic (7.29e-3)" "unprognostic (9.71e-2)" "unprognostic (1.64e-3)" "unprognostic (9.72e-2)" "unprognostic (2.98e-1)" "unprognostic (3.34e-1)" "unprognostic (2.31e-2)" "unprognostic (6.44e-2)" "unprognostic (1.84e-3)" "unprognostic (2.06e-1)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.51e-5)" "unprognostic (5.34e-2)" 4.5 6.3 7.1 2.5 7.2 2.5 4.1 7.0 8.0 5.9 6.9 9.6 3.9 7.0 4.3 3.4 6.1 3.7 5.7 7.0 7.9 5.4 5.3 3.4 2.8 7.5 7.6 7.2 3.6 11.8 8.6 0.9 7.6 5.3 4.4 5.0 4.3 5.8 1.8 3.8 5.3 7.9 7.2 4.2 6.3 1.0 7.2 8.0 5.4 1.9 2.6 5.3 4.1 7.3 0.0 1.5 23.4 11.0 0.2 0.0 3.7 4.4 9.3 6.3 11.5 2.2 8.8 4.4 2.5 3.9 0.0 0.1 10.4 4.0 6.2 0.0 9.5 7.4 3.3 3.2 1.4 6.8 2.2 4.7 3.3 2.9 6.5 9.5 11.5 25.1 2.4 9.9 7.5 0.0 20.2 0.0 37.3 4.2 10.2 29.8 11.3 0.2 6.5 0.0 0.0 16.8 0.0 0.1 0.9 13.9 2.0 1.3 7.2 3.2 6.7 0.3 0.0 1.8 0.2 14.9 9.9 6.2 0.0 0.0 0.7 0.0 1.7 1.0 3.0 2.6 2.4 2.4 0.9 1.9 3.9 2.4 0.0 2.1 0.2 2.4 1.2 1.4 7.1 7.2 7.0 8.0 7.0 7.9 7.5 7.6 7.6 7.2 7.2 7.3 2.9 3.2 0.0 20.5 6.6 0.6 2.0 1.9 1.8 3.8 1.5 2.2 4.0 4.3 1.8 1.8 4.2 0.1 1.2 1.9 1.9 7.7 0.6 1.7 3.0 4.5 3.6 3.4 37.4 5.7 0.8 4.0 3.6 0.5 2.5 5.2 5.0 4.1 1.1 0.0 39.4 1.9 8.2 0.9 0.0 0.8 7.2 0.8 0.0 22.5 0.5 5.1 2.1 58.3 59.0 4.7 2.2 8.6 1.5 1.0 3.8 5.6 0.6 1.6 13.1 2.8 4.1 0.6 0.5 1.8 0.6 0.0 1.9 4.5 3.3 1.0 ZCCHC18 "PNMA7B, SIZN2" ENSG00000166707 "Zinc finger CCHC-type containing 18" P0CG32 X 104112131-104115842 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 5.0;ovary: 4.2" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 4.2;NK-cells: 9.2;Oligodendrocyte precursor cells: 6.6;Sertoli cells: 6.6" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 2.5;Karpas-707: 4.6;SH-SY5Y: 3.1" "Low region specificity" "Detected in all" "HPA034940, HPA078516" Uncertain Approved Vesicles NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "HPA034940: AB_10671098, HPA078516: " "unprognostic (7.20e-2)" "unprognostic (7.71e-4)" "unprognostic (8.29e-2)" "unprognostic (4.21e-2)" "unprognostic (1.04e-1)" "unprognostic (1.89e-3)" "unprognostic (2.20e-2)" "unprognostic (3.22e-2)" "unprognostic (7.59e-2)" "unprognostic (3.34e-1)" "unprognostic (4.44e-6)" "unprognostic (4.05e-2)" "unprognostic (1.02e-6)" "unprognostic (3.82e-2)" "unprognostic (4.02e-1)" "unprognostic (3.91e-2)" "unprognostic (4.14e-3)" 0.5 0.8 3.0 1.3 2.9 0.4 0.3 2.9 3.0 1.8 1.1 0.7 0.3 1.5 0.2 0.3 1.3 0.4 0.5 2.7 5.0 0.4 0.1 0.4 2.0 2.2 2.5 4.2 0.9 0.0 1.6 0.1 2.2 0.8 0.3 1.2 0.2 0.6 0.1 0.2 2.0 0.6 2.4 2.2 0.5 1.0 4.9 0.4 0.3 0.1 2.0 0.6 0.7 2.1 0.0 0.1 1.9 1.3 0.1 0.0 0.1 0.4 0.0 0.3 0.3 0.1 0.0 2.5 0.0 0.1 0.4 0.0 1.1 0.0 0.1 0.7 0.9 0.4 0.1 0.0 0.2 1.4 0.4 0.1 0.0 0.2 0.0 1.1 0.3 0.1 0.0 4.6 0.1 0.0 0.0 0.0 1.0 0.0 0.3 1.7 0.4 0.0 0.2 0.2 1.3 3.1 0.1 0.0 0.0 0.2 0.0 0.1 0.8 0.1 0.5 0.1 0.6 0.1 0.0 1.2 0.0 1.4 0.4 0.0 0.0 0.0 0.4 0.0 0.6 0.7 0.3 0.5 0.0 0.8 0.3 0.4 0.0 0.0 0.0 0.0 0.2 0.1 3.0 2.9 2.9 3.0 2.7 5.0 2.2 2.5 2.2 2.4 4.9 2.1 0.9 0.0 0.6 3.3 4.0 0.1 0.2 0.0 0.0 0.8 0.3 0.3 0.7 0.0 1.3 1.8 0.0 0.0 1.7 0.0 0.0 0.1 0.1 0.6 0.9 1.2 4.2 0.8 2.6 0.2 0.0 1.2 0.0 0.3 0.0 1.3 0.7 0.0 0.0 1.7 1.5 0.0 0.0 0.3 0.4 0.3 1.5 0.1 1.8 0.0 0.1 3.4 9.2 6.6 0.3 0.0 0.0 1.2 1.7 0.1 0.0 0.2 1.5 1.0 6.6 0.2 2.4 0.0 0.2 0.1 0.0 0.0 3.6 1.0 0.0 0.1 ZCCHC3 "C20orf99, dJ1103G7.7" ENSG00000247315 "Zinc finger CCHC-type containing 3" Q9NUD5 20 297570-300321 "Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042972 Approved Vesicles NA NA "Cluster 10: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Vesicles "HPA042972: AB_10959663" "unprognostic (5.98e-3)" "unprognostic (1.38e-1)" "unprognostic (1.26e-2)" "unprognostic (1.01e-3)" "unprognostic (2.13e-1)" "unprognostic (3.04e-1)" "unprognostic (1.30e-2)" "unprognostic (1.90e-1)" "unprognostic (3.29e-1)" "unprognostic (6.55e-2)" "prognostic favorable (1.29e-4)" "unprognostic (4.30e-1)" "unprognostic (3.34e-3)" "unprognostic (6.33e-2)" "unprognostic (1.88e-1)" "unprognostic (3.67e-1)" "unprognostic (1.74e-2)" 9.9 11.3 14.5 11.7 14.1 17.8 8.4 15.8 16.8 10.8 15.9 8.9 9.8 11.2 12.5 6.8 13.0 8.3 9.8 13.5 19.5 10.9 10.0 8.6 17.7 14.8 15.7 18.2 10.8 11.7 10.9 20.1 15.1 9.2 7.5 8.5 8.8 10.7 9.8 6.1 11.4 8.1 13.2 15.4 10.3 9.6 17.7 23.1 8.9 12.6 15.7 9.8 6.3 14.2 24.0 18.4 56.7 28.4 18.3 18.6 33.6 14.7 16.2 16.2 16.7 28.4 14.0 21.8 9.6 9.5 16.7 32.6 29.2 16.5 15.3 11.8 26.8 44.1 9.3 90.0 21.2 50.9 11.7 18.2 19.2 9.9 11.7 16.8 26.2 24.4 55.7 21.5 12.7 10.6 38.8 62.1 50.7 23.3 19.6 56.5 27.1 27.7 14.4 15.2 23.5 34.7 17.5 34.9 46.8 24.2 16.0 93.8 11.4 16.6 16.3 6.8 17.8 39.1 53.9 42.3 6.0 32.4 16.3 2.5 1.2 2.2 1.6 0.7 1.5 1.7 1.4 1.3 0.9 2.1 1.6 1.6 0.4 1.1 0.5 2.1 1.4 0.8 14.5 14.1 15.8 16.8 13.5 19.5 14.8 15.7 15.1 13.2 17.7 14.2 17.3 0.0 9.1 8.8 12.6 15.8 22.7 3.5 11.4 26.9 16.1 12.8 7.6 17.2 4.9 9.2 8.4 22.4 22.3 13.0 3.9 5.9 0.7 22.6 28.0 16.4 21.0 17.9 6.8 5.4 13.4 14.5 8.2 14.9 0.0 16.1 19.2 10.2 11.0 37.0 8.0 16.2 4.1 9.8 9.7 2.1 17.4 11.5 12.4 8.4 11.0 19.6 8.2 7.1 12.3 5.2 10.3 10.5 8.9 16.3 12.2 6.8 8.9 22.1 6.6 14.2 12.3 5.8 7.6 7.2 5.7 20.7 11.1 21.2 13.3 16.0 ZDHHC13 "FLJ10852, FLJ10941, HIP14L" ENSG00000177054 "Zinc finger DHHC-type palmitoyltransferase 13" Q8IUH4 11 19117099-19176422 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 120.5;Urothelial cells: 103.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 136.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016759, HPA018791" Uncertain Supported "Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Vesicles "Golgi apparatus" "HPA016759: AB_1858993, HPA018791: AB_1858992" "unprognostic (1.43e-2)" "unprognostic (4.00e-3)" "unprognostic (1.08e-1)" "unprognostic (1.11e-3)" "unprognostic (2.95e-2)" "unprognostic (1.34e-2)" "unprognostic (1.55e-2)" "unprognostic (1.57e-1)" "unprognostic (3.57e-3)" "unprognostic (3.03e-2)" "unprognostic (1.63e-1)" "unprognostic (2.16e-1)" "unprognostic (6.95e-3)" "unprognostic (1.15e-1)" "unprognostic (7.93e-2)" "unprognostic (2.17e-1)" "unprognostic (2.76e-2)" 4.8 5.7 5.2 7.8 5.2 9.7 8.9 6.6 7.1 9.3 6.6 16.9 11.2 6.7 5.1 37.2 12.9 8.7 9.1 5.4 5.7 9.2 2.2 6.1 9.6 5.5 5.0 5.3 11.2 14.9 11.7 6.2 5.8 8.2 18.2 16.1 10.2 5.4 1.6 18.8 11.3 6.1 5.3 5.7 18.5 14.4 5.0 11.7 8.7 2.9 22.4 22.4 15.4 5.2 41.6 19.3 18.0 15.5 6.3 7.2 17.3 19.4 17.8 21.3 24.4 11.7 9.7 21.1 13.1 16.3 47.9 61.3 26.0 12.8 23.3 26.4 22.6 11.1 12.6 9.7 14.6 15.2 18.5 8.3 14.7 9.0 12.5 19.9 136.8 28.9 10.7 10.3 22.1 13.5 19.6 12.2 15.1 38.7 17.6 21.3 25.0 5.0 21.9 27.0 31.3 23.0 23.2 28.0 10.7 17.3 13.2 17.6 39.6 18.9 13.2 29.2 15.8 8.7 28.5 19.2 22.6 15.5 33.6 11.6 4.7 32.7 8.5 7.9 7.8 8.7 6.6 9.6 5.9 5.5 6.2 8.3 6.0 6.3 6.4 5.6 9.4 4.6 5.2 5.2 6.6 7.1 5.4 5.7 5.5 5.0 5.8 5.3 5.0 5.2 8.1 9.6 10.7 28.7 9.6 24.2 22.3 27.2 14.2 12.0 7.5 4.8 34.1 12.8 41.3 16.5 10.4 8.7 10.6 20.1 5.9 25.1 120.5 21.5 6.6 11.3 15.6 11.6 27.2 19.2 18.8 9.2 24.5 30.8 12.0 16.2 12.8 0.9 6.1 16.8 34.9 24.7 36.7 6.8 8.3 46.6 7.8 6.2 3.6 9.4 20.8 52.8 18.6 19.6 20.9 20.4 16.4 2.2 10.4 47.4 15.5 3.5 57.0 8.8 0.0 5.4 7.4 58.1 31.7 21.3 36.2 6.3 11.4 7.7 21.4 103.0 ZDHHC14 "FLJ20984, NEW1CP" ENSG00000175048 "Zinc finger DHHC-type palmitoyltransferase 14" Q8IZN3 6 157381133-157678157 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 161.7;Horizontal cells: 122.8;Inhibitory neurons: 108.1;Oligodendrocyte precursor cells: 315.2;Oligodendrocytes: 221.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in many" 4 "HDLM-2: 50.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013437, HPA063754" Approved Uncertain Vesicles NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 70: Brain - Nervous system development" "Cluster 44: HDLM-2 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "HPA013437: , HPA063754: AB_2685113" "unprognostic (1.66e-2)" "unprognostic (1.27e-2)" "unprognostic (1.58e-2)" "unprognostic (3.98e-2)" "unprognostic (1.59e-1)" "unprognostic (6.78e-3)" "unprognostic (1.84e-1)" "unprognostic (6.02e-2)" "unprognostic (2.87e-2)" "unprognostic (1.63e-1)" "prognostic favorable (6.93e-4)" "unprognostic (3.94e-2)" "unprognostic (5.01e-3)" "unprognostic (1.89e-1)" "unprognostic (7.95e-2)" "unprognostic (4.43e-1)" "unprognostic (2.63e-1)" 2.9 1.6 7.3 1.8 7.6 2.5 1.6 9.7 6.8 5.3 1.1 2.4 2.8 12.4 0.4 1.7 2.0 2.3 5.2 7.5 5.1 4.6 4.4 3.0 2.4 12.5 9.1 1.4 2.5 5.6 1.6 2.2 10.9 3.5 1.7 1.3 2.1 1.4 2.3 1.4 4.1 6.1 13.5 3.1 3.8 3.3 10.8 0.9 1.7 3.9 2.4 2.4 1.9 22.7 2.6 2.7 0.8 3.8 2.0 1.5 8.7 4.1 3.7 2.8 2.5 3.3 1.9 6.4 1.4 3.3 5.4 1.3 2.2 2.2 2.5 50.9 3.2 12.7 1.0 1.5 2.7 1.7 2.8 1.1 2.3 2.9 1.2 2.4 4.3 2.8 10.4 4.7 1.6 1.7 1.1 4.2 1.6 5.1 3.2 0.2 0.4 3.9 5.8 1.1 6.3 1.9 4.8 3.1 3.5 1.6 0.4 2.0 6.0 4.2 3.1 8.3 5.2 1.1 1.3 0.9 1.5 4.5 4.7 0.0 0.0 0.0 0.1 0.0 0.2 0.4 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.0 1.3 0.0 0.1 7.3 7.6 9.7 6.8 7.5 5.1 12.5 9.1 10.9 13.5 10.8 22.7 23.4 3.2 0.0 45.4 9.8 12.9 2.1 3.0 4.0 25.3 5.8 8.0 18.3 12.8 1.4 7.3 6.2 12.5 11.2 7.4 11.7 7.5 10.7 5.0 16.6 15.1 2.4 4.2 161.7 3.1 2.2 11.4 6.1 9.4 0.0 7.7 22.5 23.1 11.4 122.8 108.1 9.8 6.1 15.5 6.7 5.9 8.1 8.8 10.6 65.6 3.8 5.4 7.2 315.2 221.0 2.7 8.5 10.1 4.5 14.2 6.0 3.8 0.4 6.0 0.0 6.2 8.4 7.2 10.0 1.5 8.4 21.1 6.6 4.6 11.5 2.7 ZDHHC17 "HIP14, HYPH, KIAA0946" ENSG00000186908 "Zinc finger DHHC-type palmitoyltransferase 17" Q8IUH5 12 76764103-76853696 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 102.2;Inhibitory neurons: 95.1;Oligodendrocytes: 115.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 17.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016807, HPA058674" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 12: NES - Nervous system development" "Cluster 65: Plasmacytoid DCs - Unknown function" "Golgi apparatus, Vesicles" "HPA016807: AB_1858999, HPA058674: AB_2732626" "unprognostic (1.06e-1)" "unprognostic (2.26e-2)" "unprognostic (2.63e-2)" "unprognostic (3.04e-1)" "unprognostic (6.12e-2)" "unprognostic (2.83e-2)" "unprognostic (2.35e-3)" "unprognostic (3.09e-1)" "unprognostic (8.38e-2)" "unprognostic (1.04e-1)" "unprognostic (1.56e-3)" "unprognostic (5.42e-2)" "prognostic unfavorable (7.11e-5)" "unprognostic (1.77e-2)" "unprognostic (2.69e-1)" "unprognostic (2.98e-1)" "unprognostic (1.71e-2)" 15.6 14.1 18.6 12.1 20.4 23.7 16.1 23.1 25.9 15.8 11.8 13.7 7.5 21.7 12.3 8.0 12.8 10.5 12.5 19.8 18.9 11.0 9.8 10.6 14.8 18.2 18.6 20.1 10.2 12.7 11.0 16.4 18.9 14.1 10.1 31.0 8.1 12.8 11.8 10.2 10.3 14.6 19.2 14.4 8.5 12.8 19.4 14.9 11.8 14.2 11.4 11.7 11.7 27.8 8.2 9.5 30.1 15.4 17.6 18.5 14.6 16.2 13.4 10.5 9.2 7.8 5.8 11.2 9.5 15.9 10.5 7.5 12.1 10.1 16.2 9.5 12.6 16.4 13.1 12.0 11.9 16.5 13.9 17.6 10.3 10.0 14.7 35.2 12.2 15.2 18.0 5.2 13.8 7.6 12.0 21.9 22.1 3.6 11.3 16.1 10.7 12.3 12.0 12.3 11.7 20.1 17.8 6.4 10.7 25.7 14.4 16.3 16.9 14.3 11.0 8.8 9.3 8.1 8.5 11.9 5.4 7.6 15.0 6.2 2.3 5.7 3.6 2.4 2.9 2.5 2.9 2.6 2.8 3.9 3.0 2.5 5.9 2.0 2.5 17.1 1.3 1.5 18.6 20.4 23.1 25.9 19.8 18.9 18.2 18.6 18.9 19.2 19.4 27.8 33.4 32.1 18.3 75.7 20.1 7.1 10.4 9.8 12.5 54.6 9.9 10.7 21.3 12.8 15.5 12.9 39.6 20.3 74.1 5.0 0.0 8.0 11.3 11.8 23.8 24.8 19.2 12.0 102.2 4.7 10.2 21.2 7.1 10.1 41.2 20.7 20.3 10.6 8.8 28.6 95.1 7.5 8.2 12.3 19.4 13.7 20.2 14.9 5.4 54.4 14.9 26.1 18.6 88.4 115.8 6.8 4.5 21.1 13.5 10.2 8.4 5.5 18.0 38.1 0.0 32.3 22.0 17.7 22.6 9.5 5.5 5.6 18.1 19.6 6.2 5.5 ZDHHC20 "DHHC20, FLJ25952" ENSG00000180776 "Zinc finger DHHC-type palmitoyltransferase 20" Q5W0Z9 13 21372571-21459370 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 95.0" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 434.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014483, HPA014702" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" "HPA014483: AB_1859000, HPA014702: AB_1859001" "unprognostic (1.31e-1)" "unprognostic (2.16e-3)" "unprognostic (7.31e-3)" "unprognostic (8.89e-2)" "unprognostic (3.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.06e-3)" "unprognostic (3.77e-1)" "unprognostic (1.24e-2)" "unprognostic (1.26e-2)" "prognostic unfavorable (6.55e-4)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (3.76e-2)" "unprognostic (7.65e-2)" "unprognostic (6.15e-2)" "unprognostic (1.13e-2)" 10.9 9.2 15.2 17.6 52.9 30.0 11.5 51.8 23.3 16.2 0.0 16.9 19.3 13.8 9.6 30.2 10.9 17.1 7.9 12.0 27.0 6.7 9.8 17.0 18.0 70.8 40.7 9.7 9.0 8.9 4.4 18.8 60.3 15.1 16.1 5.6 8.5 12.2 4.0 22.1 19.0 15.2 35.1 16.1 39.5 31.7 40.7 22.6 16.4 9.4 19.5 22.9 9.3 95.0 32.9 16.4 27.7 18.1 24.5 26.7 68.3 35.6 36.3 23.3 20.6 33.8 102.5 34.8 19.3 44.7 23.8 52.7 30.5 26.5 44.8 40.0 20.4 61.8 11.7 19.6 14.1 43.3 25.8 24.2 19.4 23.6 16.2 30.0 37.6 45.9 17.3 14.9 35.3 27.2 62.0 17.2 22.9 87.3 18.0 49.8 49.1 12.7 28.9 59.7 25.2 11.4 46.0 28.7 19.3 28.6 27.0 21.8 62.6 25.0 24.0 41.7 27.4 15.6 19.9 37.7 18.2 23.6 73.1 12.6 16.2 3.8 10.1 14.9 9.3 4.6 8.7 8.7 8.4 3.4 8.1 8.4 3.0 11.2 13.8 4.1 10.4 13.5 15.2 52.9 51.8 23.3 12.0 27.0 70.8 40.7 60.3 35.1 40.7 95.0 27.6 51.3 31.5 29.0 19.9 1.0 7.8 1.4 18.2 7.4 21.9 13.7 7.4 14.3 20.7 11.0 8.4 20.7 34.7 35.5 0.0 8.5 91.3 23.4 25.2 25.7 24.0 8.4 69.1 12.2 20.9 13.6 53.0 34.5 14.0 16.1 20.0 20.8 21.7 18.5 80.0 29.1 2.0 92.5 3.2 81.2 15.5 49.0 1.8 46.9 48.4 3.7 30.9 54.8 434.3 22.8 25.5 10.9 18.1 14.5 30.3 6.3 11.7 9.5 19.7 12.7 11.6 10.4 14.1 28.1 1.6 44.6 28.4 9.7 25.1 25.6 ZDHHC24 ENSG00000174165 "Zinc finger DHHC-type containing 24" Q6UX98 11 66520637-66546235 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016619 Approved Approved Vesicles,Cytosol NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Cytosol" "HPA016619: AB_2288672" "unprognostic (2.77e-1)" "unprognostic (2.51e-1)" "unprognostic (2.52e-1)" "unprognostic (1.55e-3)" "prognostic unfavorable (3.28e-4)" "unprognostic (8.76e-2)" "unprognostic (7.74e-3)" "unprognostic (7.11e-2)" "unprognostic (6.20e-2)" "unprognostic (1.41e-1)" "unprognostic (3.73e-2)" "unprognostic (1.48e-1)" "unprognostic (8.10e-2)" "unprognostic (6.99e-3)" "unprognostic (3.10e-1)" "unprognostic (4.88e-1)" "unprognostic (1.35e-1)" 5.2 6.9 5.8 3.3 4.5 5.0 4.7 4.2 5.4 3.6 5.8 3.5 2.8 4.3 5.1 4.3 3.9 2.2 3.6 4.9 5.2 6.2 4.6 4.5 4.3 5.5 5.2 2.7 7.1 6.0 4.7 2.5 4.8 4.5 2.1 2.6 5.0 2.7 2.9 5.1 4.7 1.9 4.4 7.2 4.8 3.7 6.4 3.1 5.9 1.1 3.0 4.0 3.4 4.5 5.2 7.4 2.4 6.5 5.8 4.7 6.2 3.9 3.4 3.1 2.1 6.5 7.7 1.6 11.5 3.3 8.3 11.9 1.9 3.4 2.1 7.6 4.9 2.9 3.7 4.1 5.5 3.4 6.9 5.6 6.2 2.5 3.6 3.7 5.1 13.0 4.2 4.3 4.0 10.4 7.4 8.6 5.3 12.2 7.6 8.8 5.3 9.3 3.9 3.6 3.5 5.6 6.7 6.5 11.6 2.7 9.5 2.4 8.0 7.1 2.4 8.3 3.1 6.9 2.2 2.1 6.2 1.5 8.2 3.0 5.9 1.0 7.3 5.7 6.6 6.4 6.0 8.4 7.2 7.5 3.8 5.9 2.2 8.0 5.0 23.1 6.6 6.1 5.8 4.5 4.2 5.4 4.9 5.2 5.5 5.2 4.8 4.4 6.4 4.5 21.7 12.8 8.3 7.8 21.9 8.0 15.2 26.8 10.8 9.6 21.5 15.2 4.5 22.8 17.3 23.9 10.4 33.0 49.9 29.0 9.8 50.3 13.5 15.1 14.4 23.3 14.4 6.3 7.6 49.4 37.2 15.0 17.9 19.8 8.9 18.5 23.2 14.9 63.9 23.5 7.0 17.8 20.3 42.8 14.8 12.1 7.5 27.9 17.8 5.6 36.4 16.9 46.4 4.0 8.5 42.8 40.6 9.8 15.8 24.9 54.8 35.2 14.7 10.3 19.7 11.2 15.1 29.6 4.1 21.6 8.1 24.1 23.3 18.5 21.8 23.1 ZFAND3 "FLJ13222, TEX27" ENSG00000156639 "Zinc finger AN1-type containing 3" Q9H8U3 6 37819727-38154624 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 821.8;Late spermatids: 3021.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016755 Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" "HPA016755: AB_1859011" "unprognostic (3.32e-1)" "unprognostic (3.04e-2)" "unprognostic (1.36e-1)" "unprognostic (2.89e-2)" "unprognostic (1.60e-1)" "unprognostic (1.14e-1)" "unprognostic (9.24e-2)" "unprognostic (1.37e-1)" "unprognostic (1.07e-1)" "unprognostic (1.36e-2)" "unprognostic (9.30e-2)" "unprognostic (1.48e-2)" "unprognostic (9.60e-3)" "unprognostic (1.01e-1)" "unprognostic (2.94e-1)" "unprognostic (7.41e-2)" "unprognostic (4.33e-1)" 44.2 42.3 36.6 31.7 38.0 42.6 36.4 36.8 36.4 42.6 33.2 50.3 39.3 41.2 35.3 37.4 33.4 36.3 51.1 37.0 41.4 47.7 53.3 37.8 28.1 46.2 40.8 32.3 39.0 56.6 33.8 48.8 41.5 35.3 32.1 39.4 32.8 46.1 137.8 33.8 39.5 46.9 39.2 31.6 42.0 113.0 38.2 39.7 52.0 67.3 29.3 49.3 31.2 42.9 59.1 33.8 116.8 82.8 72.4 75.9 42.5 88.6 115.6 87.3 92.8 68.4 33.4 24.6 71.8 106.8 96.2 39.5 48.3 73.4 122.3 102.2 30.6 75.6 17.3 65.3 171.0 29.5 59.4 96.1 93.7 91.7 157.0 101.6 76.8 56.9 37.3 48.1 68.4 50.6 50.2 27.0 33.4 84.5 38.4 52.4 48.4 29.6 79.5 94.0 74.2 63.2 54.6 43.6 151.5 98.1 70.2 61.5 81.5 87.2 66.2 47.5 58.8 47.3 47.7 74.2 32.4 47.1 91.9 0.5 1.7 6.1 1.5 1.7 1.1 1.3 1.1 1.2 0.9 1.9 0.9 1.5 6.0 1.6 1.3 2.9 1.5 0.9 36.6 38.0 36.8 36.4 37.0 41.4 46.2 40.8 41.5 39.2 38.2 42.9 25.4 22.4 11.5 241.0 27.0 27.3 30.9 20.0 52.9 25.8 19.8 19.4 23.0 25.8 11.6 47.8 22.9 35.0 23.2 55.2 74.3 27.3 821.8 25.4 26.6 28.1 16.2 22.5 332.7 29.3 33.1 27.2 31.6 33.2 5.1 33.9 27.5 48.8 33.8 30.3 262.9 30.5 6.1 43.7 44.3 3021.1 38.8 49.2 14.2 283.9 32.9 47.4 34.0 276.0 316.4 38.9 29.1 55.3 28.3 52.3 57.6 38.2 17.2 21.6 32.9 32.9 31.2 63.5 54.1 41.3 30.1 86.1 31.2 21.1 21.5 61.2 ZFP37 ZNF906 ENSG00000136866 "ZFP37 zinc finger protein" Q9Y6Q3 9 113038377-113056759 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 15.5;Oligodendrocyte precursor cells: 23.6;Oligodendrocytes: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 2.4" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA049112 Uncertain Approved Nucleoplasm,Vesicles Yes No "Cluster 4: T-regs - Cell cycle regulation" "Cluster 21: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Vesicles" "HPA049112: AB_2680637" "unprognostic (3.18e-1)" "unprognostic (9.57e-2)" "unprognostic (5.62e-2)" "unprognostic (3.54e-3)" "prognostic favorable (1.96e-4)" "unprognostic (7.84e-2)" "unprognostic (8.09e-2)" "unprognostic (2.70e-3)" "unprognostic (1.47e-1)" "unprognostic (2.53e-2)" "unprognostic (2.51e-2)" "unprognostic (1.38e-3)" "unprognostic (4.22e-2)" "unprognostic (9.46e-2)" "unprognostic (3.67e-1)" "unprognostic (4.86e-1)" "unprognostic (2.07e-1)" 1.6 1.7 2.2 1.3 2.9 0.2 2.8 4.4 2.5 3.0 0.5 1.6 0.8 4.5 1.8 1.2 2.5 1.3 1.5 1.9 2.7 2.3 0.6 1.3 1.2 2.3 2.2 7.1 1.3 2.9 3.8 1.3 2.5 2.5 1.0 6.3 0.9 1.8 1.4 1.2 1.1 2.5 2.5 2.0 1.2 2.2 3.3 1.2 2.9 1.9 1.3 1.8 1.6 4.0 0.6 1.7 7.2 6.0 3.9 7.5 3.7 2.3 3.4 2.5 2.1 0.0 1.7 4.2 1.8 2.4 3.3 1.5 0.0 0.9 3.9 5.2 0.8 0.2 3.5 1.9 2.1 0.0 0.8 2.1 0.7 3.0 5.8 6.1 1.4 0.0 0.4 3.6 5.2 0.0 0.0 0.0 7.4 4.4 0.0 0.0 10.0 0.6 1.9 0.0 6.1 5.8 7.1 1.5 1.4 3.5 6.0 0.0 0.6 5.8 2.5 6.9 3.5 1.4 2.9 0.0 4.5 0.1 3.6 0.1 0.0 0.0 0.9 0.2 0.7 0.9 0.8 0.9 0.3 0.4 0.6 0.9 0.1 0.7 0.0 0.0 2.4 0.3 2.2 2.9 4.4 2.5 1.9 2.7 2.3 2.2 2.5 2.5 3.3 4.0 3.4 0.0 0.5 5.5 2.1 0.3 0.9 1.3 2.2 10.3 1.4 2.8 8.0 0.0 0.5 0.0 6.2 0.8 1.6 0.1 3.9 1.6 1.0 0.6 4.9 3.2 1.2 0.0 9.2 0.9 1.6 3.8 2.6 0.6 5.7 2.5 2.5 1.3 0.5 6.7 15.5 0.6 4.1 0.3 0.3 0.2 2.1 0.8 0.0 3.7 0.5 3.4 3.1 23.6 29.7 0.4 1.3 2.2 1.1 0.5 0.1 3.1 0.4 6.0 6.6 6.4 4.2 5.6 3.2 2.7 0.0 0.1 1.3 2.6 0.3 0.4 ZFP90 "KIAA1954, NK10, ZNF756" ENSG00000184939 "ZFP90 zinc finger protein" Q8TF47 16 68530090-68576072 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029017 Uncertain Supported "Vesicles,Plasma membrane,Centrosome" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Vesicles, Plasma membrane, Centrosome" "HPA029017: AB_10669653" "unprognostic (3.27e-1)" "unprognostic (1.71e-2)" "unprognostic (1.56e-1)" "unprognostic (1.45e-2)" "unprognostic (3.11e-1)" "unprognostic (2.47e-1)" "unprognostic (3.68e-3)" "unprognostic (1.78e-1)" "unprognostic (5.19e-2)" "unprognostic (7.33e-2)" "unprognostic (1.35e-3)" "unprognostic (3.43e-1)" "prognostic favorable (1.78e-4)" "unprognostic (1.47e-2)" "unprognostic (2.37e-1)" "unprognostic (1.33e-1)" "unprognostic (9.60e-2)" 7.0 6.3 19.4 7.2 18.6 6.1 11.1 27.0 31.1 11.7 9.9 8.2 2.9 10.8 12.2 5.9 9.5 6.5 8.0 18.2 18.1 8.6 5.4 6.7 9.5 15.2 14.6 12.7 7.4 15.7 13.5 5.8 15.3 9.2 6.2 12.7 6.3 8.8 8.2 9.3 7.3 9.3 11.0 10.5 8.1 9.7 18.2 13.4 8.2 9.0 11.3 7.5 8.0 20.3 10.6 11.4 20.9 19.9 18.1 19.2 9.7 9.7 11.0 13.2 15.2 8.0 7.0 11.5 12.7 12.6 11.1 9.7 12.9 12.5 15.0 10.1 4.7 3.0 2.2 13.4 14.0 0.0 10.3 17.2 20.2 12.1 16.8 23.5 10.7 21.2 5.8 4.1 16.3 18.8 11.6 10.7 7.8 6.3 8.5 21.0 6.5 7.6 9.0 7.2 23.5 17.9 28.1 2.1 10.5 15.4 16.8 14.9 8.4 12.2 7.2 10.4 5.8 8.1 15.9 14.0 4.1 4.0 9.9 7.9 1.5 2.5 5.2 1.6 6.7 4.5 4.9 6.0 2.0 3.3 6.7 5.9 0.3 4.3 1.0 2.3 5.8 2.7 19.4 18.6 27.0 31.1 18.2 18.1 15.2 14.6 15.3 11.0 18.2 20.3 13.1 19.2 8.9 18.6 15.1 3.4 6.4 10.5 14.8 21.1 8.5 9.4 10.5 10.0 9.0 20.2 14.6 3.4 11.8 1.5 7.9 10.2 20.6 9.8 14.4 10.9 16.1 13.2 34.0 6.1 1.7 14.7 5.1 6.5 12.0 30.3 11.0 5.2 6.9 18.5 41.4 4.7 4.1 7.9 5.7 13.2 16.4 8.3 3.6 11.2 6.4 13.0 19.6 31.2 35.5 6.5 3.2 17.7 7.2 5.9 1.3 8.1 24.2 17.3 0.0 12.4 11.0 12.1 19.1 8.6 4.5 1.4 18.7 13.7 4.5 4.0 ZFPM1 "FOG, FOG1, ZC2HC11A, ZNF89A" ENSG00000179588 "Zinc finger protein, FOG family member 1" Q8IX07 16 88453280-88537031 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 35.3;Muller glia cells: 58.0;Theca cells: 37.4" "Cancer enhanced" "Detected in all" "stomach cancer: 12.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 19.3;K-562: 29.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046603 Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Vesicles, Cytosol" "HPA046603: AB_2679718" "unprognostic (1.29e-1)" "unprognostic (2.42e-1)" "unprognostic (3.08e-2)" "unprognostic (3.32e-2)" "unprognostic (1.13e-1)" "unprognostic (9.21e-2)" "unprognostic (1.24e-1)" "unprognostic (7.13e-3)" "unprognostic (1.02e-1)" "unprognostic (1.55e-2)" "unprognostic (5.58e-2)" "unprognostic (3.05e-2)" "unprognostic (2.49e-4)" "unprognostic (1.99e-2)" "unprognostic (3.32e-1)" "unprognostic (4.89e-2)" "prognostic favorable (4.24e-4)" 2.1 2.5 4.8 1.9 2.4 9.2 1.9 5.7 5.8 2.3 4.2 1.7 12.4 2.2 1.0 1.8 4.0 1.5 4.8 5.8 2.1 3.7 8.6 2.1 2.7 3.5 3.2 2.2 10.4 1.4 5.6 0.8 2.6 3.2 0.8 0.7 2.8 1.3 1.6 3.7 6.8 0.2 1.6 4.9 13.7 5.7 3.3 1.5 4.0 0.3 1.2 2.3 2.0 1.6 1.4 3.8 2.8 5.9 0.5 0.1 11.9 4.0 0.5 1.3 0.4 12.1 1.5 5.9 3.0 0.6 1.4 9.5 0.1 3.3 0.3 4.6 2.5 19.3 8.1 10.7 2.1 1.1 6.2 1.3 2.1 1.4 0.5 1.4 1.3 1.6 29.2 0.4 1.0 7.3 6.9 7.0 1.9 9.3 3.2 2.0 1.3 2.9 1.3 4.8 7.7 12.8 4.9 0.3 3.9 1.4 3.1 3.1 4.8 4.9 3.1 2.2 0.8 1.4 1.0 0.5 1.4 2.3 4.9 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.8 2.4 5.7 5.8 5.8 2.1 3.5 3.2 2.6 1.6 3.3 1.6 16.7 3.2 2.2 12.4 4.8 0.9 6.1 0.7 0.0 20.7 13.5 25.8 17.2 5.7 0.4 1.8 29.2 0.4 27.5 10.8 1.9 1.3 0.7 24.1 23.7 6.3 6.0 4.8 6.8 5.1 0.2 10.9 14.3 20.1 0.0 16.0 5.0 8.8 0.9 35.3 8.0 6.7 0.0 5.3 1.2 1.1 0.9 7.5 1.8 8.4 1.6 58.0 2.1 5.5 13.4 2.9 6.2 1.5 9.5 1.4 1.3 1.3 0.4 23.9 0.0 16.1 12.4 0.7 1.0 1.9 1.4 0.3 9.6 37.4 5.2 2.1 ZFYVE16 "KIAA0305, PPP1R69" ENSG00000039319 "Zinc finger FYVE-type containing 16" Q7Z3T8 5 80408013-80483379 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 182.0;Oligodendrocytes: 620.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 21.2;neutrophil: 21.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-MEL-30: 80.7" "Low region specificity" "Detected in all" "HPA035935, HPA035936" Supported Enhanced Vesicles,Cytosol No No "Cluster 6: Non-specific - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 52: Non-specific - Transcription" "Vesicles, Cytosol" "HPA035935: AB_10672076, HPA035936: AB_10669662" "unprognostic (1.11e-1)" "unprognostic (3.98e-2)" "unprognostic (1.78e-2)" "unprognostic (3.26e-1)" "unprognostic (7.19e-2)" "unprognostic (2.57e-2)" "unprognostic (7.25e-3)" "unprognostic (6.91e-2)" "unprognostic (4.00e-1)" "unprognostic (8.83e-2)" "unprognostic (1.29e-1)" "unprognostic (2.15e-1)" "unprognostic (3.04e-1)" "unprognostic (4.64e-2)" "unprognostic (4.95e-2)" "unprognostic (6.91e-2)" "unprognostic (4.23e-2)" 8.4 8.7 5.1 8.1 12.0 5.2 8.7 5.7 6.4 15.1 4.3 6.4 5.1 12.7 2.5 7.2 7.2 11.2 14.0 4.1 8.2 9.5 10.3 9.1 5.6 7.0 8.5 12.3 6.4 9.0 3.9 13.0 7.6 8.5 6.3 8.6 5.0 6.6 6.1 4.3 6.8 9.9 6.5 9.0 6.6 9.3 8.3 5.0 9.5 8.4 4.5 9.5 4.7 15.5 11.9 13.4 23.4 21.9 14.0 14.3 15.5 17.6 15.2 15.4 20.7 9.9 16.5 7.9 12.5 14.6 16.4 11.9 17.2 14.4 16.9 5.1 10.9 8.6 16.3 11.3 11.6 2.6 6.3 15.4 7.5 12.9 12.4 12.4 18.0 7.3 8.5 12.0 16.8 14.9 5.7 2.5 5.3 6.1 6.5 11.7 48.3 8.4 12.9 22.1 8.8 19.5 25.3 11.6 80.7 14.1 20.2 7.7 16.0 9.2 10.3 14.3 14.6 3.6 7.6 7.8 12.1 8.0 21.0 21.2 4.5 2.5 1.8 2.8 1.0 3.6 0.9 1.6 1.8 3.2 0.7 0.9 21.3 3.0 5.4 3.0 1.0 0.4 5.1 12.0 5.7 6.4 4.1 8.2 7.0 8.5 7.6 6.5 8.3 15.5 49.3 25.6 22.2 127.0 25.8 18.2 14.0 16.4 15.4 94.9 23.4 18.2 52.3 14.3 33.8 31.3 114.7 22.1 28.9 20.3 9.8 16.2 7.4 47.6 85.6 33.1 21.6 7.8 87.7 12.3 11.8 33.7 23.9 37.5 10.1 59.7 35.7 16.8 26.5 80.8 114.0 11.3 2.0 59.8 71.5 7.0 37.9 71.4 19.6 64.6 34.7 26.3 17.5 182.0 620.2 16.4 20.2 44.4 19.0 16.5 16.3 13.6 49.9 75.3 32.9 58.6 43.3 49.0 22.0 15.6 25.4 37.4 17.5 44.7 12.9 20.1 ZFYVE27 "FLJ32919, SPG33" ENSG00000155256 "Zinc finger FYVE-type containing 27" Q5T4F4 10 97737121-97760907 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037523, HPA069876" Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 10: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles" Cytosol "HPA037523: AB_10672351, HPA069876: AB_2686218" "unprognostic (2.21e-1)" "unprognostic (1.91e-1)" "prognostic unfavorable (6.91e-4)" "unprognostic (3.12e-1)" "unprognostic (3.42e-2)" "unprognostic (9.76e-2)" "unprognostic (1.22e-1)" "unprognostic (2.30e-2)" "unprognostic (2.48e-2)" "unprognostic (7.15e-2)" "unprognostic (2.05e-3)" "unprognostic (5.24e-2)" "unprognostic (3.38e-3)" "prognostic favorable (7.54e-4)" "unprognostic (4.18e-2)" "unprognostic (1.26e-2)" "prognostic favorable (7.80e-4)" 14.4 27.9 33.1 12.9 32.1 23.2 15.8 29.2 35.9 20.6 34.8 25.6 24.8 16.5 22.9 16.5 20.3 12.1 17.8 35.5 33.6 28.3 32.6 17.7 16.1 32.6 31.4 25.9 23.7 19.2 38.3 9.5 33.2 22.0 16.3 28.4 18.9 10.3 12.8 18.2 30.6 8.5 29.1 29.1 19.8 23.0 33.5 12.7 20.4 5.9 13.1 16.8 17.0 32.4 17.7 21.4 12.6 28.1 14.1 9.8 17.2 17.7 18.5 20.3 19.7 19.1 35.9 27.2 19.8 12.8 25.9 38.8 18.4 17.2 10.6 28.3 18.6 12.9 23.1 18.1 18.1 20.9 24.9 16.0 20.4 19.9 15.2 32.4 11.5 22.5 19.6 17.9 15.3 13.8 16.9 39.4 10.3 15.3 16.4 19.2 12.7 13.0 19.5 10.8 10.1 19.7 11.9 9.9 47.2 11.5 21.8 20.5 12.4 10.2 11.9 15.6 34.2 20.6 18.6 14.3 25.3 26.5 11.9 4.8 5.8 9.3 9.6 6.2 8.2 7.1 6.6 7.9 5.4 6.7 7.5 8.3 8.2 6.8 9.2 5.6 9.5 8.3 33.1 32.1 29.2 35.9 35.5 33.6 32.6 31.4 33.2 29.1 33.5 32.4 10.0 3.2 11.4 14.0 22.1 8.2 12.8 11.3 18.8 29.9 11.1 8.9 7.2 14.3 9.7 14.7 58.4 7.4 21.2 33.9 7.9 14.9 5.2 14.3 7.8 11.0 20.3 14.3 33.6 16.0 5.7 10.1 19.4 11.4 14.0 17.3 10.8 10.9 8.2 37.0 35.2 15.6 14.2 8.8 5.7 1.5 9.6 11.0 10.6 16.9 11.2 14.8 15.5 12.5 20.2 13.9 26.1 9.1 13.4 13.8 35.5 8.6 16.6 43.7 19.7 6.7 9.9 8.9 7.6 10.4 5.5 13.5 17.9 10.9 14.7 17.7 ZFYVE9 "MADHIP, PPP1R173, SARA, SMADIP" ENSG00000157077 "Zinc finger FYVE-type containing 9" O95405 1 52142089-52348671 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 131.0;Inhibitory neurons: 162.6;Oligodendrocyte precursor cells: 80.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017702, HPA065852, HPA065862" Approved Enhanced Vesicles,Cytosol NA NA "Cluster 34: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Cytosol" "CAB017702: AB_1128462, HPA065852: AB_2685568, HPA065862: AB_2685570" "unprognostic (5.05e-2)" "unprognostic (4.78e-2)" "unprognostic (2.58e-2)" "unprognostic (1.51e-1)" "unprognostic (7.15e-2)" "unprognostic (3.87e-1)" "unprognostic (2.87e-3)" "unprognostic (6.11e-2)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "unprognostic (2.47e-2)" "unprognostic (5.36e-2)" "unprognostic (1.17e-3)" "unprognostic (2.14e-1)" "unprognostic (3.69e-1)" "unprognostic (1.99e-3)" "unprognostic (1.73e-2)" 9.3 8.2 13.7 3.3 14.5 1.1 11.2 20.5 16.6 12.4 31.1 8.3 5.7 12.0 7.3 9.1 10.0 6.9 7.2 15.5 13.2 12.9 9.2 9.8 2.2 13.0 13.2 16.3 15.0 25.7 8.9 6.3 14.2 11.1 8.2 13.7 9.2 11.1 25.7 10.7 5.5 11.2 10.9 3.6 7.4 13.8 13.5 5.3 16.9 20.2 3.4 8.9 8.6 13.5 17.9 8.3 11.7 15.1 27.5 25.0 19.2 14.2 18.8 16.5 18.8 9.6 1.4 0.0 8.7 20.0 22.7 6.5 20.8 22.5 25.1 0.1 14.6 5.1 9.3 11.4 18.0 4.5 2.9 16.7 24.9 14.2 31.9 20.1 24.0 11.8 8.0 3.2 22.2 3.9 6.5 3.3 15.4 4.7 14.8 5.7 20.1 1.7 9.4 38.5 9.9 10.2 15.9 13.4 18.4 23.2 6.2 5.9 22.3 16.6 6.7 12.8 8.6 4.5 2.9 2.2 11.8 5.4 6.8 1.3 0.0 0.1 0.2 0.0 0.4 0.2 0.3 0.1 0.0 0.1 0.3 0.2 0.2 0.1 0.0 0.1 0.0 0.1 13.7 14.5 20.5 16.6 15.5 13.2 13.0 13.2 14.2 10.9 13.5 13.5 11.5 9.6 5.9 61.7 0.7 5.1 10.0 4.0 10.8 19.9 6.6 5.7 13.6 7.2 9.4 1.8 4.2 5.5 1.1 8.8 7.9 6.4 12.6 6.3 19.1 9.3 17.5 0.0 131.0 7.4 5.3 11.0 23.4 7.9 1.3 16.0 5.0 8.5 0.5 23.5 162.6 8.1 2.0 0.6 1.3 17.3 15.2 0.5 7.2 45.9 0.2 10.0 1.0 80.9 37.5 4.1 7.9 16.6 3.5 7.8 8.2 10.2 2.5 14.3 13.1 20.9 8.3 45.5 46.8 11.7 7.4 2.9 3.8 15.0 6.3 6.4 ZG16B "HRPE773, JCLN2, PRO1567" ENSG00000162078 "Zymogen granule protein 16B" Q96DA0 16 2830169-2839585 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 717 "salivary gland: 63926.2" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 194.0;Basal respiratory cells: 181.6;Breast glandular cells: 154.9;Club cells: 343.9;Intestinal goblet cells: 232.2;Prostatic glandular cells: 398.1;Urothelial cells: 357.4" "Cancer enhanced" "Detected in many" "prostate cancer: 47.1" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "classical monocyte: 6.3;intermediate monocyte: 11.4;non-classical monocyte: 7.4" "Lineage enriched" "Detected in many" 7 "monocytes: 11.4" "Cell line enhanced" "Detected in some" "MCF7: 27.1;OE19: 57.5;SK-BR-3: 24.1;T-47d: 22.2" "Not detected" "Not detected" "HPA041125, HPA053549" Enhanced Approved Nucleoplasm,Vesicles "Secreted to digestive system" NA NA 690000 "Cluster 7: Monocytes - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles Nucleoplasm "HPA041125: AB_10794264, HPA053549: AB_2682184" "unprognostic (5.29e-2)" "unprognostic (2.71e-1)" "unprognostic (4.37e-2)" "prognostic favorable (3.48e-6)" "unprognostic (1.39e-3)" "unprognostic (1.94e-2)" "unprognostic (2.34e-3)" "unprognostic (4.13e-2)" "unprognostic (1.01e-1)" "unprognostic (3.45e-3)" "unprognostic (1.37e-1)" "unprognostic (1.47e-2)" "unprognostic (1.67e-1)" "unprognostic (1.17e-1)" "unprognostic (2.17e-1)" "unprognostic (1.04e-1)" "unprognostic (8.33e-2)" 2.5 13.2 0.0 3.9 0.0 4.6 33.1 0.0 0.1 33.0 0.0 13.6 11.5 0.6 1.5 25.3 4.4 34.4 9.0 0.0 0.0 2.6 8.2 3.3 0.3 0.0 0.8 10.3 46.6 30.4 6.0 4.8 0.1 89.1 17.8 0.0 63926.2 7.1 6.1 47.7 9.6 0.4 0.0 4.2 33.2 4.4 0.0 0.2 2.9 0.1 5.9 11.2 16.3 0.0 0.0 1.1 0.0 0.0 0.3 1.9 0.2 0.0 0.0 0.0 0.0 0.3 2.5 0.0 0.3 0.0 0.2 2.1 0.0 4.4 0.0 0.0 0.0 9.0 2.8 2.4 1.6 0.0 0.0 0.1 0.2 0.0 1.2 0.1 0.0 0.0 0.2 3.6 0.2 27.1 0.0 0.4 0.1 57.5 5.0 0.0 0.0 8.6 0.2 6.3 0.0 0.0 0.1 24.1 0.0 0.1 22.2 0.0 3.1 0.1 0.5 1.9 0.1 0.0 0.5 0.3 0.3 6.5 0.3 1.7 6.3 0.0 0.0 11.4 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.4 1.2 7.4 0.0 0.5 1.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.5 9.1 194.0 181.6 0.0 0.0 154.9 82.5 0.0 70.1 343.9 1.8 0.0 0.1 2.0 107.1 0.0 5.9 7.7 3.5 1.6 2.8 58.2 0.4 0.0 28.1 3.2 1.8 21.9 13.0 5.7 1.7 0.7 0.1 14.6 0.0 0.0 232.2 140.4 4.6 0.5 5.7 0.0 4.4 83.6 0.0 5.6 0.0 0.0 0.0 0.0 46.4 65.3 0.0 0.0 398.1 12.5 0.0 74.7 0.0 0.0 0.0 19.2 1.4 0.6 9.5 24.0 0.3 2.5 21.3 76.7 357.4 ZGLP1 "GATAD3, GLP-1, GLP1" ENSG00000220201 "Zinc finger GATA like protein 1" P0C6A0 19 10304803-10309880 "Predicted intracellular proteins, Transcription factors" "Differentiation, Oogenesis, Spermatogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 9.5;Hofbauer cells: 12.7;Kupffer cells: 20.0;Macrophages: 12.6;Spermatogonia: 16.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NB-4: 32.8;U-937: 8.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA049855 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Vesicles" "HPA049855: AB_2680916" "unprognostic (1.73e-2)" "unprognostic (3.43e-3)" "unprognostic (1.42e-3)" "unprognostic (1.87e-2)" "unprognostic (1.90e-1)" "unprognostic (1.46e-4)" "unprognostic (1.18e-1)" "unprognostic (1.34e-2)" "unprognostic (3.04e-2)" "unprognostic (3.10e-2)" "unprognostic (1.10e-4)" "unprognostic (2.82e-2)" "unprognostic (6.57e-7)" "unprognostic (6.86e-2)" "unprognostic (6.21e-2)" "unprognostic (1.57e-1)" "unprognostic (2.57e-4)" 1.9 1.5 5.0 1.0 5.2 0.5 2.3 4.6 10.7 4.0 4.3 2.4 1.0 2.5 0.4 1.9 3.3 0.8 1.7 5.3 4.4 7.8 6.4 2.2 1.7 4.2 4.0 5.2 3.3 0.5 8.3 0.9 4.0 6.8 0.2 0.5 2.5 1.0 1.2 2.1 2.6 0.2 3.7 5.0 1.9 5.0 4.4 0.4 9.2 0.4 0.7 2.6 2.7 4.8 0.5 1.2 1.7 0.6 1.1 0.5 4.3 0.9 0.3 0.8 1.8 1.2 0.4 1.9 0.9 0.3 0.8 1.8 1.2 0.4 0.3 1.6 5.5 1.8 2.0 0.7 0.7 0.0 0.5 0.9 2.5 0.8 0.5 0.7 0.2 1.4 1.8 1.3 1.1 2.0 0.2 32.8 2.7 0.4 2.0 1.8 0.8 0.8 0.7 0.8 1.4 1.6 0.4 0.3 1.6 0.4 2.5 0.6 0.6 2.5 2.9 2.4 0.3 6.2 7.9 0.9 0.4 8.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 5.2 4.6 10.7 5.3 4.4 4.2 4.0 4.0 3.7 4.4 4.8 1.1 0.0 1.8 4.6 0.5 0.9 0.6 1.2 0.0 1.6 2.0 2.4 0.8 0.0 1.2 1.8 0.0 0.5 0.8 0.9 0.0 0.6 0.8 0.9 1.3 1.1 0.0 0.4 9.5 0.0 0.4 0.6 0.0 0.9 0.0 2.7 0.7 1.2 12.7 6.7 6.9 0.7 0.0 20.0 7.9 1.3 0.9 12.6 3.6 2.8 7.8 1.7 0.0 1.5 1.6 0.3 1.5 0.7 0.1 0.9 0.4 0.4 1.5 1.5 0.0 0.5 0.8 2.2 16.3 0.3 0.9 0.1 0.6 0.8 1.6 0.0 ZIC5 ENSG00000139800 "Zic family member 5" Q96T25 13 99962964-99971909 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 17.1;choroid plexus: 8.1" "Group enriched" "Detected in some" 7 "Astrocytes: 20.5;Microglial cells: 15.0;Spermatocytes: 6.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 22.0;HEK 293: 12.7;NTERA-2: 15.1;SCLC-21H: 85.5" "Group enriched" "Detected in all" 5 "basal ganglia: 18.9;cerebellum: 18.4;thalamus: 5.3" "Region enriched" "Detected in all" 7 "cerebellum: 39.7" HPA074045 Uncertain Nucleoplasm,Vesicles NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Vesicles" "HPA074045: " "unprognostic (2.78e-5)" "unprognostic (1.71e-2)" "unprognostic (2.44e-2)" "unprognostic (2.29e-3)" "unprognostic (1.07e-1)" "unprognostic (1.30e-1)" "unprognostic (4.38e-4)" "unprognostic (2.13e-2)" "unprognostic (1.02e-1)" "unprognostic (5.01e-2)" "unprognostic (1.06e-2)" "unprognostic (3.87e-2)" "unprognostic (1.13e-1)" "unprognostic (3.12e-2)" "unprognostic (4.94e-2)" 0.0 0.0 2.8 0.0 3.5 0.0 0.0 17.1 11.2 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 2.1 0.0 0.0 0.0 0.0 2.8 2.1 0.0 0.0 0.0 0.2 0.0 3.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 3.6 3.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 2.2 22.0 1.8 0.0 0.0 4.1 0.0 0.0 0.0 0.0 1.0 2.1 0.0 3.1 0.0 1.1 0.0 4.5 0.0 0.0 4.0 12.7 0.0 2.1 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.9 3.3 0.0 0.0 1.7 0.0 1.7 15.1 0.0 0.3 1.9 0.8 0.0 0.0 0.0 85.5 0.0 2.4 2.0 0.0 1.6 0.0 2.8 0.0 1.2 0.0 0.4 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 3.5 17.1 11.2 3.9 2.1 2.8 2.1 3.0 1.8 3.1 2.6 0.1 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 15.0 0.0 1.9 0.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 6.3 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZMYND19 MIZIP ENSG00000165724 "Zinc finger MYND-type containing 19" Q96E35 9 137582081-137590512 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "retina: 287.8" "Group enriched" "Detected in many" 14 "Cone photoreceptor cells: 244.0;Rod photoreceptor cells: 680.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020642, HPA050761" Supported Approved "Golgi apparatus,Vesicles" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus, Vesicles" "HPA020642: AB_1859078, HPA050761: AB_2681228" "unprognostic (2.30e-2)" "unprognostic (9.62e-3)" "unprognostic (3.45e-2)" "unprognostic (7.99e-2)" "unprognostic (2.66e-1)" "unprognostic (1.90e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.18e-1)" "unprognostic (2.48e-1)" "unprognostic (1.35e-1)" "unprognostic (9.33e-2)" "unprognostic (1.99e-2)" "unprognostic (2.39e-1)" "unprognostic (9.67e-3)" "unprognostic (4.30e-2)" "unprognostic (1.62e-1)" "unprognostic (1.72e-1)" 11.9 16.5 19.6 9.4 19.9 9.1 11.9 18.8 23.9 14.2 18.6 12.4 8.8 11.2 5.0 26.5 11.4 7.2 14.1 20.0 19.5 12.9 21.1 12.0 11.9 18.7 19.2 12.9 16.1 8.0 16.9 8.5 19.7 16.5 5.7 287.8 15.9 7.1 14.2 27.7 12.4 6.8 18.9 15.1 22.2 49.5 19.4 9.5 10.8 8.8 9.4 13.3 16.6 19.8 28.9 44.7 41.8 45.5 22.1 21.3 42.1 38.8 25.8 41.7 31.8 53.1 28.7 51.7 43.6 25.8 40.2 71.7 51.3 38.9 13.2 33.8 49.7 26.9 86.1 41.8 34.4 58.4 33.9 16.8 58.7 38.0 37.1 18.4 22.3 40.5 66.3 22.2 25.6 97.2 68.4 88.7 60.7 86.4 61.9 73.8 36.8 79.6 25.7 24.2 60.1 39.4 37.4 79.4 35.4 18.5 53.7 89.9 21.3 51.1 38.9 76.8 63.8 21.4 54.9 56.8 31.6 44.8 35.9 0.0 0.3 0.3 0.5 1.6 1.2 0.8 0.3 0.2 0.3 0.3 0.5 0.4 0.0 0.1 0.2 0.9 1.0 0.1 19.6 19.9 18.8 23.9 20.0 19.5 18.7 19.2 19.7 18.9 19.4 19.8 6.1 9.6 7.2 3.6 4.0 17.5 5.6 3.2 5.2 23.6 14.9 19.2 6.2 2.8 2.4 1.8 244.0 5.2 6.8 5.3 0.0 3.2 4.5 6.5 12.8 5.6 2.4 6.9 4.1 3.6 6.8 6.3 10.7 8.1 1.3 10.6 3.9 7.6 4.4 11.8 4.0 8.8 6.1 3.2 5.7 4.4 2.8 3.6 5.4 1.9 2.2 31.6 5.2 2.0 2.1 4.2 4.6 3.0 10.9 10.2 1.9 3.1 1.3 680.0 0.0 6.9 6.7 27.8 28.7 4.5 22.9 4.5 4.6 8.5 7.8 7.1 ZNF10 KOX1 ENSG00000256223 "Zinc finger protein 10" P21506 12 133130575-133159465 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 45.5;Excitatory neurons: 46.0;Inhibitory neurons: 48.4;Oligodendrocyte precursor cells: 54.3;Oligodendrocytes: 45.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003204 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 51: Non-specific - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Vesicles, Plasma membrane" Nucleoplasm "HPA003204: AB_1080663" "unprognostic (1.55e-2)" "unprognostic (2.77e-3)" "unprognostic (4.32e-2)" "unprognostic (1.35e-1)" "unprognostic (6.48e-2)" "unprognostic (2.67e-3)" "unprognostic (1.87e-1)" "unprognostic (6.39e-3)" "unprognostic (4.02e-3)" "unprognostic (2.13e-1)" "unprognostic (3.35e-3)" "unprognostic (2.50e-2)" "unprognostic (3.94e-2)" "unprognostic (3.41e-1)" "unprognostic (1.52e-1)" "unprognostic (4.36e-2)" "unprognostic (5.13e-3)" 6.7 14.3 4.9 3.7 5.6 8.6 12.3 8.8 7.6 14.4 6.2 10.9 3.7 15.0 23.4 6.0 12.1 10.3 8.3 5.8 8.0 10.9 10.6 7.6 5.9 4.7 6.8 22.4 13.2 17.3 45.3 5.2 5.6 15.1 6.2 13.1 8.0 12.7 4.9 8.8 7.1 8.6 5.4 6.0 10.5 15.3 7.8 7.7 21.2 6.3 5.8 10.7 8.8 7.1 3.8 2.2 10.8 0.0 11.5 4.8 6.5 4.4 3.9 5.3 3.6 3.9 2.4 0.0 6.0 4.4 2.9 1.7 6.8 3.6 3.9 0.0 6.6 8.0 10.5 4.4 3.5 5.0 2.6 5.0 3.3 5.7 6.3 7.9 4.4 6.3 6.0 0.0 6.3 1.2 12.0 10.6 11.1 2.1 4.4 9.9 6.8 5.4 4.2 7.9 10.7 7.0 8.7 1.4 3.7 4.9 6.6 5.0 4.3 3.9 3.6 3.7 3.7 0.2 0.0 12.8 1.2 1.7 3.7 0.9 0.5 1.4 2.9 0.6 3.2 3.1 3.4 4.1 1.4 3.0 6.5 3.3 0.5 6.3 0.4 3.4 0.9 1.8 4.9 5.6 8.8 7.6 5.8 8.0 4.7 6.8 5.6 5.4 7.8 7.1 6.8 0.0 9.0 39.2 39.6 3.8 5.3 3.9 45.5 15.9 9.9 9.4 7.7 4.3 7.1 0.0 31.3 4.5 9.1 1.8 1.9 2.3 24.6 11.9 7.6 5.0 12.6 5.0 46.0 1.4 2.0 15.5 21.4 11.7 10.8 5.0 1.4 4.9 2.5 5.0 48.4 3.9 6.1 3.8 4.6 6.3 2.8 9.0 3.6 21.5 1.5 9.1 2.1 54.3 45.4 1.0 2.1 6.8 16.3 2.6 2.2 2.5 2.7 16.2 0.0 6.3 14.3 20.4 15.4 21.4 3.8 3.8 21.9 6.0 3.3 1.6 ZNF132 pHZ-12 ENSG00000131849 "Zinc finger protein 132" P52740 19 58432814-58440153 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 4.0;Cone photoreceptor cells: 4.2;Early spermatids: 3.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" HPA008726 Uncertain Approved "Vesicles,Intermediate filaments" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 43: Cardiomyocytes - Nuclear processes" Vesicles "Intermediate filaments" "HPA008726: AB_1080664" "unprognostic (4.86e-2)" "unprognostic (2.03e-1)" "unprognostic (6.79e-3)" "unprognostic (3.06e-2)" "unprognostic (8.16e-2)" "unprognostic (4.78e-2)" "unprognostic (4.02e-2)" "unprognostic (2.32e-3)" "unprognostic (5.00e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.92e-4)" "unprognostic (4.51e-1)" "prognostic favorable (7.26e-13)" "unprognostic (2.70e-1)" "unprognostic (7.65e-2)" "unprognostic (6.09e-2)" "unprognostic (3.72e-1)" 1.4 2.3 1.8 1.3 1.9 0.3 2.6 4.7 2.7 2.7 4.6 1.7 1.2 1.8 3.5 1.6 3.8 1.3 3.0 1.8 1.9 3.0 0.8 1.8 1.8 1.5 2.3 3.7 1.6 8.9 3.4 1.8 1.6 2.9 1.1 5.0 3.0 3.1 1.9 2.3 1.1 2.1 1.4 2.3 1.5 3.1 1.7 1.6 5.4 1.7 2.2 1.9 1.5 2.7 1.2 1.3 3.4 1.2 3.9 3.3 0.1 2.6 3.2 2.1 2.0 0.1 1.0 3.3 0.2 3.2 2.1 1.3 0.0 3.9 1.5 0.5 5.9 0.6 1.1 0.7 3.4 1.3 2.1 3.5 1.3 3.6 2.3 2.5 2.0 0.5 0.4 0.3 4.1 0.5 0.7 0.1 3.5 0.4 1.2 0.4 0.7 0.9 1.3 1.4 3.0 3.1 1.0 0.9 1.1 3.6 0.2 3.2 2.4 2.1 0.2 0.5 0.5 4.1 0.8 0.0 1.0 0.1 1.4 0.0 0.8 0.8 0.9 1.0 2.2 1.1 1.1 0.5 1.2 1.4 1.7 1.4 0.0 1.2 1.2 1.0 1.1 0.8 1.8 1.9 4.7 2.7 1.8 1.9 1.5 2.3 1.6 1.4 1.7 2.7 0.4 0.0 0.5 1.6 0.6 0.0 0.6 0.5 0.0 1.2 0.4 0.4 4.0 1.5 0.2 0.0 4.2 0.5 0.2 0.1 0.0 0.6 3.7 1.2 1.0 0.8 0.0 1.7 2.0 0.4 0.2 0.7 2.0 0.4 1.3 1.6 0.4 0.9 0.5 3.3 2.3 0.8 0.0 0.3 0.0 0.7 0.6 0.7 0.0 0.0 0.2 1.4 0.0 1.0 2.5 0.1 0.0 0.7 0.5 0.9 0.3 1.5 0.7 1.7 0.0 0.7 0.8 2.5 0.8 0.8 0.3 0.4 0.5 0.8 0.2 0.3 ZNF133 "pHZ-13, pHZ-66, ZNF150" ENSG00000125846 "Zinc finger protein 133" P52736 20 18288283-18316996 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 37.1;Inhibitory neurons: 42.0;Oligodendrocyte precursor cells: 32.6;Oligodendrocytes: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA001493 Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Vesicles" "HPA001493: AB_1080666" "unprognostic (9.09e-3)" "unprognostic (3.24e-1)" "unprognostic (8.27e-3)" "unprognostic (6.82e-2)" "unprognostic (2.20e-2)" "unprognostic (1.54e-2)" "prognostic unfavorable (4.46e-6)" "unprognostic (6.01e-3)" "unprognostic (8.60e-2)" "unprognostic (4.17e-1)" "unprognostic (1.04e-3)" "unprognostic (7.36e-2)" "prognostic unfavorable (2.20e-5)" "unprognostic (5.86e-2)" "unprognostic (1.37e-1)" "unprognostic (1.62e-1)" "unprognostic (1.52e-1)" 12.3 13.1 16.8 4.6 17.1 4.3 14.5 19.0 19.0 17.1 20.5 15.7 5.2 13.3 16.5 14.8 14.1 7.7 11.1 16.9 17.7 18.1 13.0 10.9 5.7 16.1 16.4 17.6 16.0 11.4 21.2 8.7 16.7 18.7 6.8 10.5 12.9 8.8 14.0 16.7 10.3 10.5 15.5 15.5 12.9 10.2 16.9 7.1 17.4 9.8 5.9 14.1 15.1 17.8 10.0 10.8 8.3 12.0 19.9 13.7 17.6 9.2 13.5 11.5 16.6 8.7 11.5 2.6 5.4 10.9 13.2 21.4 8.1 24.1 10.8 2.9 5.6 6.8 9.9 19.4 14.9 5.8 1.0 13.4 16.3 9.6 28.0 15.6 11.2 11.0 8.1 2.8 10.0 10.0 7.2 9.5 6.9 11.9 10.6 6.2 11.4 6.4 11.3 6.8 11.7 11.9 7.1 18.9 13.3 11.5 7.4 15.7 8.0 12.1 5.8 8.6 9.2 9.1 9.8 0.9 3.7 3.9 7.0 1.5 3.1 2.4 5.9 2.2 3.9 3.2 5.0 4.0 3.9 3.4 3.8 4.6 1.0 8.7 3.5 2.1 4.0 2.7 16.8 17.1 19.0 19.0 16.9 17.7 16.1 16.4 16.7 15.5 16.9 17.8 3.7 6.4 9.2 18.6 2.5 2.2 2.7 7.3 3.4 7.5 4.6 7.4 7.9 5.7 5.7 1.8 4.2 5.0 0.8 2.2 3.9 4.5 14.7 5.1 7.7 4.7 1.2 3.2 37.1 2.3 3.2 5.3 5.1 4.5 7.0 7.1 5.3 4.2 4.7 3.3 42.0 4.6 2.0 3.8 0.9 25.0 7.8 2.2 0.0 21.5 1.4 3.1 4.1 32.6 31.8 3.7 1.5 4.5 2.3 3.3 2.5 3.4 5.0 5.0 0.0 4.4 3.6 6.1 2.6 3.0 3.1 2.3 1.9 3.7 3.3 3.0 ZNF143 "pHZ-1, SBF, STAF" ENSG00000166478 "Zinc finger protein 143" P52747 11 9460319-9528524 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003263, HPA003264, HPA074818" Supported Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus,Vesicles" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nuclear bodies, Golgi apparatus, Vesicles" "HPA003263: AB_1080672, HPA003264: , HPA074818: AB_2686715" "unprognostic (2.30e-2)" "unprognostic (2.12e-2)" "unprognostic (5.51e-2)" "unprognostic (9.72e-2)" "unprognostic (5.09e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (1.76e-5)" "unprognostic (4.87e-3)" "unprognostic (2.57e-3)" "unprognostic (9.56e-2)" "unprognostic (1.26e-3)" "unprognostic (1.06e-1)" "prognostic unfavorable (6.78e-4)" "unprognostic (1.20e-3)" "unprognostic (1.92e-2)" "unprognostic (1.06e-2)" "unprognostic (7.55e-2)" 9.0 6.1 8.6 11.4 10.1 18.6 9.6 17.3 9.9 10.0 10.8 9.7 9.5 10.5 14.4 9.8 10.1 8.4 9.3 7.9 9.3 8.6 9.6 9.1 15.7 9.9 8.8 13.7 7.7 7.9 7.1 10.4 11.2 8.7 9.9 16.1 8.9 8.0 17.3 10.2 8.2 9.5 9.8 11.1 7.7 16.9 9.0 18.9 14.6 11.5 14.1 11.2 8.4 14.9 20.0 18.8 23.4 15.2 18.9 17.4 21.5 21.8 17.3 16.4 17.9 26.7 24.3 19.6 9.7 17.7 14.0 22.5 23.1 17.3 24.5 20.0 27.7 18.5 27.7 18.7 15.6 25.9 17.8 15.3 20.4 22.2 19.4 21.4 16.3 17.9 20.5 23.3 18.3 17.1 24.1 10.6 26.3 23.0 19.9 21.4 21.2 12.3 14.7 24.0 16.1 15.8 24.0 16.0 14.3 20.6 14.9 14.6 15.6 21.4 15.3 15.1 19.6 11.5 21.6 33.4 13.8 14.8 12.5 39.1 24.6 57.3 28.0 24.9 25.0 23.0 24.6 22.9 20.9 18.2 22.8 19.6 45.1 19.4 28.2 10.1 29.7 19.6 8.6 10.1 17.3 9.9 7.9 9.3 9.9 8.8 11.2 9.8 9.0 14.9 17.9 6.4 12.1 6.2 14.7 26.6 34.1 12.1 17.6 9.3 8.7 13.2 15.5 7.2 10.3 5.5 8.4 10.0 17.1 10.1 3.9 12.5 20.3 18.7 14.9 13.0 6.6 25.4 8.1 11.5 16.2 14.5 9.7 16.3 14.0 7.7 6.8 7.6 9.9 5.0 7.4 6.9 14.2 8.3 22.0 10.0 11.8 15.8 10.6 12.2 16.3 15.5 17.5 7.5 9.8 14.1 7.7 6.8 15.4 20.1 6.3 7.7 15.0 14.3 59.2 18.3 16.7 50.5 21.3 12.8 23.4 18.3 18.1 7.3 7.9 26.9 ZNF169 MGC51961 ENSG00000175787 "Zinc finger protein 169" Q14929 9 94259298-94301829 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 18.4;Inhibitory neurons: 16.7;NK-cells: 15.5;Oligodendrocyte precursor cells: 14.1;Oligodendrocytes: 19.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041769, HPA061185" Uncertain Approved "Nucleoplasm,Nuclear speckles,Vesicles,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 51: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear speckles" "Vesicles, Cytosol" "HPA041769: AB_2677662, HPA061185: " "unprognostic (1.07e-1)" "unprognostic (2.29e-1)" "unprognostic (1.03e-1)" "unprognostic (3.39e-1)" "unprognostic (3.27e-2)" "unprognostic (9.08e-3)" "unprognostic (1.18e-3)" "unprognostic (7.33e-2)" "unprognostic (2.27e-1)" "unprognostic (7.45e-2)" "unprognostic (6.79e-2)" "unprognostic (1.69e-2)" "unprognostic (1.49e-4)" "unprognostic (6.32e-2)" "unprognostic (1.15e-1)" "unprognostic (1.69e-1)" "unprognostic (2.15e-4)" 3.0 2.7 3.8 4.4 4.4 3.2 3.9 4.3 4.8 5.4 3.4 4.3 2.9 3.9 4.2 2.6 4.8 1.7 2.6 3.8 2.4 3.7 2.1 3.2 6.0 3.7 2.6 5.4 3.3 2.3 2.7 2.1 3.8 4.2 5.5 4.2 3.9 2.6 4.6 5.2 5.7 2.8 1.8 6.1 4.1 2.6 3.5 3.8 4.8 1.8 5.1 4.0 4.1 5.7 3.0 2.6 2.8 4.9 1.5 3.4 3.1 1.1 2.0 2.2 2.3 1.8 4.3 7.3 1.4 1.7 2.2 5.8 5.7 2.7 2.9 4.0 6.3 5.1 6.5 3.3 1.8 7.8 5.0 3.0 2.9 1.8 2.8 2.8 2.7 6.8 4.6 2.1 2.8 2.9 3.7 4.4 4.6 6.2 3.2 3.1 2.0 2.3 1.9 2.5 2.9 3.5 1.9 3.5 1.4 2.7 2.2 3.2 3.1 2.0 2.6 2.6 2.2 3.9 1.5 1.4 1.9 5.2 1.9 2.2 3.0 3.2 2.4 3.4 3.1 3.0 2.9 1.7 2.1 4.0 3.0 4.1 2.5 3.3 2.6 2.0 3.1 1.7 3.8 4.4 4.3 4.8 3.8 2.4 3.7 2.6 3.8 1.8 3.5 5.7 2.0 3.2 0.5 10.4 8.0 0.3 2.2 1.3 1.2 4.8 1.0 1.3 1.2 1.5 2.6 1.8 4.2 0.5 3.9 2.5 0.0 1.1 1.0 0.6 1.4 2.3 1.2 3.8 18.4 0.9 0.8 1.8 2.6 0.5 0.0 6.3 2.5 0.8 0.7 5.0 16.7 4.1 0.0 4.4 1.6 1.0 5.9 4.1 0.0 7.5 7.8 2.3 15.5 14.1 19.9 1.2 3.1 3.4 2.6 2.6 4.3 1.0 2.4 4.5 0.0 2.9 1.7 5.2 3.6 0.7 0.4 0.4 4.7 3.7 2.1 2.4 ZNF213 "CR53, ZKSCAN21, ZSCAN53" ENSG00000085644 "Zinc finger protein 213" O14771 16 3129777-3142804 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 22.7;Late spermatids: 58.3;Sertoli cells: 19.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035000, HPA056750" Uncertain Approved "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear membrane" "Vesicles, Cytosol" "HPA035000: AB_10669997, HPA056750: AB_2683225" "unprognostic (1.94e-1)" "unprognostic (1.62e-2)" "unprognostic (3.25e-1)" "unprognostic (1.87e-2)" "unprognostic (1.31e-2)" "unprognostic (4.05e-3)" "prognostic unfavorable (6.74e-4)" "unprognostic (4.72e-2)" "unprognostic (1.25e-1)" "unprognostic (2.31e-1)" "unprognostic (1.66e-1)" "unprognostic (2.90e-1)" "unprognostic (4.73e-1)" "unprognostic (7.67e-2)" "unprognostic (2.02e-1)" "unprognostic (3.33e-1)" "unprognostic (1.57e-1)" 4.3 6.7 5.0 3.6 4.9 3.9 4.6 5.7 6.2 5.1 0.9 5.7 5.5 6.5 1.7 6.9 5.1 3.2 5.6 4.9 3.3 4.6 2.5 3.5 5.7 7.1 4.6 6.5 7.2 4.9 6.7 2.1 4.7 5.7 1.2 4.3 10.4 3.0 11.5 10.0 6.8 2.3 3.4 4.9 5.7 17.9 5.1 2.5 5.2 1.2 0.9 5.7 5.2 5.4 3.6 11.1 4.9 11.3 4.7 3.8 6.0 6.4 2.6 3.3 3.9 3.6 7.2 4.3 6.2 4.2 4.9 8.4 2.2 7.1 1.3 9.2 8.3 2.4 13.4 7.0 8.8 7.5 7.8 3.7 8.7 4.4 1.8 2.5 2.5 8.2 8.0 9.4 2.2 15.1 7.0 9.1 8.3 3.8 8.4 9.4 5.7 8.1 2.6 2.4 10.0 8.5 9.7 5.7 4.7 3.1 7.5 12.8 6.3 6.8 6.2 7.7 4.5 5.2 5.4 6.4 2.7 9.9 5.3 0.0 0.5 1.3 1.2 0.9 1.1 0.9 1.2 0.8 0.5 1.5 1.5 1.1 1.3 1.6 0.7 1.2 0.7 0.8 5.0 4.9 5.7 6.2 4.9 3.3 7.1 4.6 4.7 3.4 5.1 5.4 4.1 0.0 1.1 3.6 1.9 1.9 1.5 2.1 2.8 5.3 4.8 4.2 4.4 1.5 1.7 0.0 2.1 1.8 3.4 10.2 1.9 4.0 22.7 3.0 3.1 3.4 2.4 2.1 3.2 4.9 2.0 3.9 4.6 4.4 4.5 4.8 4.6 1.4 3.2 8.4 3.5 6.0 0.0 5.1 1.7 58.3 6.5 3.6 0.0 1.0 4.4 5.6 5.2 0.5 4.6 5.2 4.2 7.2 1.3 2.1 14.6 2.5 1.5 5.2 19.7 3.9 4.1 9.5 4.5 4.8 2.0 1.4 2.3 3.5 6.6 1.8 ZNF215 "ZKSCAN11, ZSCAN43" ENSG00000149054 "Zinc finger protein 215" Q9UL58 11 6926404-7001004 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 4.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 13.7;Inhibitory neurons: 8.5;Plasma cells: 27.5;Spermatogonia: 9.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-698: 19.8" "Low region specificity" "Detected in many" "HPA047243, HPA051010" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 11: Basophils - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Vesicles" "HPA047243: , HPA051010: AB_2681308" "unprognostic (2.18e-2)" "unprognostic (1.52e-1)" "unprognostic (2.29e-2)" "unprognostic (1.08e-1)" "unprognostic (8.18e-2)" "unprognostic (4.76e-2)" "unprognostic (1.01e-4)" "unprognostic (2.02e-1)" "unprognostic (1.50e-2)" "unprognostic (1.05e-1)" "unprognostic (3.44e-1)" "unprognostic (1.45e-2)" "unprognostic (9.01e-3)" "unprognostic (4.29e-3)" "unprognostic (7.89e-2)" "unprognostic (1.21e-1)" "unprognostic (1.90e-1)" 0.4 0.4 0.4 1.3 0.4 0.7 1.3 0.2 0.5 0.8 0.1 2.0 2.2 0.7 0.6 0.9 0.4 0.5 0.4 0.4 0.5 1.0 0.3 0.5 3.4 0.5 0.4 0.8 2.2 0.0 0.2 0.2 0.4 0.8 2.6 0.4 1.4 0.4 0.2 0.5 1.9 0.5 0.2 1.6 0.8 1.5 0.6 1.2 0.8 0.1 4.2 1.1 0.7 0.3 2.9 1.1 1.8 0.2 1.2 1.7 6.4 7.0 5.7 3.6 6.5 0.2 0.0 10.1 2.1 3.2 4.3 3.1 4.8 6.4 6.3 0.0 7.5 0.0 0.3 0.0 1.2 6.5 0.0 3.2 3.1 0.1 7.0 1.4 5.3 0.1 11.5 3.1 1.3 0.0 0.1 0.0 8.9 0.0 1.6 0.0 0.0 1.3 0.1 5.3 0.0 0.2 0.0 2.4 0.0 4.4 0.1 2.4 2.8 2.0 5.8 2.4 0.0 0.3 0.1 19.8 4.8 0.0 1.9 1.5 0.4 0.1 0.1 0.2 0.0 0.6 0.1 0.3 0.4 0.5 0.3 0.1 0.6 0.2 0.1 0.7 0.2 0.3 0.4 0.4 0.2 0.5 0.4 0.5 0.5 0.4 0.4 0.2 0.6 0.3 0.2 0.0 0.0 0.3 2.5 0.4 1.7 1.0 1.8 0.6 0.7 0.3 0.2 0.0 0.9 7.3 6.2 0.4 0.1 0.9 1.9 0.1 0.3 0.8 1.8 0.6 1.2 2.5 13.7 1.8 2.6 1.1 0.0 0.9 1.3 0.6 0.0 0.9 0.4 3.3 8.5 3.5 0.0 0.3 0.0 0.3 0.0 0.8 1.8 3.7 0.0 0.1 0.0 1.5 0.4 0.3 0.8 0.0 27.5 0.6 2.0 1.1 0.4 0.0 0.0 0.2 0.7 5.6 9.1 2.3 0.3 0.0 0.8 2.2 2.2 0.8 ZNF229 ENSG00000278318 "Zinc finger protein 229" Q9UJW7 19 44417519-44448578 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 7.5;Rod photoreceptor cells: 6.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTERT-HME1: 6.9" HPA001494 Uncertain Approved "Vesicles,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Vesicles "Plasma membrane" "HPA001494: AB_1080692" "unprognostic (2.59e-1)" "unprognostic (7.41e-4)" "unprognostic (2.13e-1)" "unprognostic (1.08e-1)" "unprognostic (3.90e-1)" "unprognostic (2.17e-1)" "unprognostic (3.34e-2)" "unprognostic (7.18e-3)" "unprognostic (1.17e-2)" "unprognostic (4.66e-2)" "unprognostic (4.18e-2)" "unprognostic (5.04e-3)" "prognostic favorable (8.43e-5)" "unprognostic (3.66e-3)" "unprognostic (2.01e-2)" "unprognostic (2.18e-1)" "unprognostic (4.34e-1)" 0.5 1.7 1.3 0.1 1.4 0.1 1.0 1.3 1.6 1.0 1.7 0.9 0.7 1.1 1.1 0.7 1.9 0.5 1.4 1.4 1.4 0.8 0.7 0.6 0.3 1.3 1.3 2.3 0.8 2.7 1.3 1.1 1.3 1.2 0.1 4.5 0.7 0.8 0.8 0.3 0.4 0.8 1.2 0.6 0.6 0.7 1.5 1.1 2.0 1.2 0.3 0.8 0.5 1.6 0.0 3.7 2.7 0.0 2.9 2.4 0.0 4.4 1.4 2.1 2.8 0.0 0.6 0.0 1.7 2.5 3.4 1.3 0.0 2.8 1.4 0.0 1.4 0.4 1.2 0.3 5.0 0.0 0.0 3.4 0.0 1.7 6.9 2.9 2.0 0.0 0.1 0.0 3.0 0.0 0.0 0.0 3.4 0.0 1.0 0.0 0.0 1.3 2.1 5.5 0.7 1.0 1.9 0.3 0.0 2.0 0.0 0.0 1.9 1.3 0.1 0.5 0.1 3.1 2.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.3 0.1 0.0 1.5 0.0 0.0 0.0 0.1 1.3 1.4 1.3 1.6 1.4 1.4 1.3 1.3 1.3 1.2 1.5 1.6 1.4 0.0 0.0 5.9 0.4 0.1 0.7 2.0 1.8 5.8 2.1 2.2 3.7 0.0 1.3 0.0 4.2 0.9 0.0 0.2 3.9 1.7 0.7 1.6 1.7 1.3 0.0 2.1 3.1 1.2 0.6 1.0 2.6 1.0 0.0 3.4 1.4 0.2 0.7 1.7 4.5 0.3 0.0 0.6 0.0 0.5 0.9 0.3 0.0 1.0 0.1 4.7 0.0 7.5 2.2 2.0 0.3 1.9 0.0 1.6 0.3 1.6 4.5 6.9 0.0 1.0 1.5 1.8 2.4 1.4 0.0 0.8 0.2 3.4 0.5 0.9 ZNF232 ZSCAN11 ENSG00000167840 "Zinc finger protein 232" Q9UNY5 17 5105541-5123116 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 18.1;Spermatogonia: 21.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027309, HPA028611" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 37: B-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Vesicles, Cytosol" "HPA027309: AB_10603464, HPA028611: AB_2672700" "unprognostic (4.20e-2)" "unprognostic (2.06e-3)" "unprognostic (3.69e-1)" "unprognostic (5.59e-3)" "unprognostic (5.21e-2)" "unprognostic (5.90e-3)" "prognostic unfavorable (4.66e-4)" "unprognostic (3.12e-2)" "unprognostic (5.46e-3)" "unprognostic (2.49e-2)" "prognostic favorable (6.55e-4)" "unprognostic (3.28e-2)" "unprognostic (3.49e-3)" "unprognostic (2.22e-2)" "unprognostic (2.28e-1)" "unprognostic (1.11e-1)" "unprognostic (8.61e-3)" 1.8 1.2 3.0 1.1 3.5 0.4 1.9 3.4 4.3 2.7 3.1 2.7 1.0 2.4 2.4 1.6 2.3 1.3 2.0 3.1 3.5 2.3 2.1 1.5 1.9 3.6 3.1 3.4 2.8 1.9 1.6 1.5 3.5 2.1 1.3 2.3 1.9 1.3 2.0 1.4 1.8 1.9 3.1 1.9 2.2 2.6 3.5 1.6 2.4 1.8 1.4 1.8 1.8 4.2 5.8 4.3 6.9 7.0 2.4 1.0 3.7 2.8 1.4 2.7 3.7 6.7 1.4 11.5 3.4 1.0 4.0 3.9 4.9 2.8 1.6 4.6 7.4 2.0 10.0 6.0 3.5 0.0 3.4 1.9 3.0 2.9 2.5 1.9 2.0 13.7 10.0 4.1 3.3 2.8 10.1 4.0 13.5 4.9 4.6 8.5 4.4 7.8 2.2 0.8 7.2 4.7 5.4 2.1 4.6 5.2 1.1 2.8 3.2 2.7 4.6 2.1 5.5 5.5 9.3 3.0 6.9 0.3 4.6 1.3 1.9 1.9 4.2 2.0 5.2 12.5 4.7 5.8 3.9 11.4 7.0 6.5 0.1 5.7 1.2 7.4 4.3 3.5 3.0 3.5 3.4 4.3 3.1 3.5 3.6 3.1 3.5 3.1 3.5 4.2 4.2 0.0 2.6 2.0 5.2 4.2 2.9 4.0 5.7 5.7 3.8 6.6 5.6 0.0 3.9 5.5 0.0 3.9 3.5 3.1 3.9 7.0 8.6 5.5 6.8 5.2 1.2 2.1 3.4 4.0 5.0 3.4 1.5 2.2 0.0 4.0 3.6 3.9 6.1 0.0 3.3 2.4 0.0 3.8 1.3 6.9 3.7 2.9 0.0 3.7 1.8 4.2 0.0 3.0 8.1 3.7 7.6 5.3 1.4 4.1 2.6 3.2 6.5 3.9 0.0 4.4 4.4 18.1 21.7 3.3 4.7 2.1 3.2 3.4 3.8 1.8 ZNF266 HZF1 ENSG00000174652 "Zinc finger protein 266" Q14584 19 9412461-9435571 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 74.2" "Low region specificity" "Detected in all" "HPA026836, HPA054110" Uncertain Supported "Nucleoplasm,Vesicles,Rods & Rings" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 51: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Nucleoplasm, Rods & Rings" "HPA026836: AB_2672018, HPA054110: AB_2682383" "unprognostic (2.50e-2)" "prognostic favorable (1.41e-4)" "unprognostic (2.27e-2)" "unprognostic (1.04e-1)" "unprognostic (7.60e-2)" "prognostic favorable (3.94e-6)" "unprognostic (1.72e-2)" "prognostic favorable (4.47e-4)" "unprognostic (4.59e-2)" "unprognostic (9.00e-3)" "prognostic favorable (3.03e-5)" "unprognostic (2.92e-3)" "prognostic unfavorable (1.82e-4)" "unprognostic (7.76e-2)" "unprognostic (1.08e-1)" "unprognostic (3.56e-2)" "prognostic favorable (9.15e-5)" 21.0 17.6 8.7 12.7 9.1 17.5 22.8 10.5 10.7 26.3 10.1 22.8 10.2 20.6 53.3 17.5 21.7 9.7 15.3 8.4 8.9 16.3 15.4 21.8 23.8 8.9 8.9 24.2 15.1 15.7 20.1 15.0 9.0 31.5 15.9 12.6 19.0 14.6 11.4 25.1 29.4 14.0 8.8 44.1 19.4 16.7 9.1 27.6 26.3 8.6 27.9 20.0 20.3 9.9 21.5 5.4 13.0 26.6 10.8 15.3 10.3 19.4 18.9 19.1 27.5 10.1 7.1 22.5 12.6 10.7 7.4 6.3 19.3 10.8 22.1 6.8 29.6 27.1 21.8 13.9 9.2 16.9 17.3 16.4 16.0 9.6 14.3 15.5 14.2 25.7 18.0 0.0 16.7 2.1 25.8 74.2 16.6 9.9 16.5 9.6 16.4 16.9 13.6 22.2 13.0 19.5 10.5 11.0 14.0 14.0 8.8 14.2 13.7 16.6 6.9 23.1 11.8 32.1 55.6 28.0 4.5 14.8 11.3 4.0 3.5 4.9 9.6 4.1 6.8 4.8 5.7 7.4 2.9 5.3 7.5 8.1 2.0 11.1 5.4 2.7 7.5 4.8 8.7 9.1 10.5 10.7 8.4 8.9 8.9 8.9 9.0 8.8 9.1 9.9 8.8 0.0 14.3 10.4 15.3 4.0 5.9 5.3 11.4 8.0 9.0 8.8 5.5 4.3 8.7 3.7 12.5 4.8 22.4 7.2 3.9 5.5 0.7 5.0 5.4 7.5 9.5 14.3 12.5 3.7 3.3 6.6 11.2 6.5 12.0 12.9 10.8 3.1 4.8 8.4 12.0 7.1 6.1 11.4 7.2 1.4 6.2 9.1 5.4 14.0 11.3 4.2 20.6 14.1 15.1 4.7 5.2 4.5 10.5 5.6 7.6 1.4 6.6 9.5 6.6 7.2 6.2 5.5 8.7 6.4 4.7 4.7 17.1 6.5 7.4 6.4 ZNF302 "ZNF135L, ZNF140L, ZNF327" ENSG00000089335 "Zinc finger protein 302" Q9NR11 19 34677639-34686397 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 203.2;choroid plexus: 142.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA059503 Approved "Vesicles,Cytokinetic bridge" Yes No "Cluster 6: Non-specific - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Vesicles, Cytokinetic bridge" "HPA059503: AB_2684043" "unprognostic (3.52e-1)" "unprognostic (1.85e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (2.03e-5)" "unprognostic (2.25e-1)" "unprognostic (1.32e-2)" "unprognostic (2.78e-1)" "unprognostic (1.50e-2)" "unprognostic (4.33e-3)" "unprognostic (1.82e-2)" "unprognostic (4.63e-2)" "unprognostic (3.39e-2)" "prognostic unfavorable (5.41e-4)" "unprognostic (2.34e-1)" "unprognostic (1.21e-1)" "unprognostic (3.94e-2)" "prognostic favorable (9.85e-5)" 13.7 18.1 139.4 10.2 142.4 4.6 24.0 142.8 203.2 17.5 142.3 20.0 12.4 19.5 21.6 9.1 18.5 11.1 25.4 139.0 140.3 19.8 19.0 14.6 17.8 140.2 141.5 28.0 24.4 21.5 16.7 11.9 141.4 18.0 15.4 45.2 13.5 18.8 37.2 12.8 15.7 14.8 140.7 19.4 14.9 15.5 140.7 17.2 19.1 30.4 16.7 18.0 12.1 147.3 10.5 16.0 33.3 13.2 30.8 23.6 11.6 17.8 21.8 16.0 17.3 11.9 9.5 16.3 21.7 13.5 12.0 8.5 16.3 10.4 17.1 1.3 13.6 31.2 18.0 0.3 16.5 0.3 2.4 22.3 15.0 9.9 1.8 20.0 13.8 11.4 0.3 0.9 25.2 5.5 16.9 16.7 15.1 18.9 10.6 12.5 27.0 9.1 16.9 14.0 14.8 24.1 16.2 6.0 21.9 17.7 12.7 24.8 13.6 7.4 17.6 6.8 8.9 18.6 35.1 5.1 6.8 2.4 33.9 28.1 10.1 17.2 14.9 10.0 20.7 23.3 17.0 14.0 8.8 25.0 28.0 22.3 7.5 19.4 13.4 20.3 14.9 9.1 139.4 142.4 142.8 203.2 139.0 140.3 140.2 141.5 141.4 140.7 140.7 147.3 32.2 28.9 27.6 41.8 33.2 26.8 34.0 16.0 19.9 56.5 24.4 30.9 58.9 25.8 22.1 22.0 52.1 16.8 26.6 10.4 45.0 17.5 31.3 12.7 29.7 34.3 19.9 20.8 41.5 11.4 6.8 41.0 21.4 11.8 29.1 63.0 28.5 11.8 10.1 48.8 42.4 13.4 14.2 14.5 44.9 6.3 59.4 15.7 24.9 29.0 17.8 73.5 42.2 54.8 76.1 10.0 16.4 51.1 14.8 40.1 20.6 14.3 25.6 88.8 52.6 73.5 40.5 67.0 40.2 15.7 21.5 5.5 29.3 44.8 11.6 30.8 ZNF326 "FLJ20403, ZAN75, Zfp326, ZIRD" ENSG00000162664 "Zinc finger protein 326" Q5BKZ1 1 89995110-90035533 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 52.6" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 373.2;Rod photoreceptor cells: 458.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028450, HPA028461, HPA028466" Supported Enhanced "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 79: Retina - Phototransduction" "Cluster 20: HeLa - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Golgi apparatus, Vesicles" "HPA028450: AB_2672616, HPA028461: AB_10601777, HPA028466: AB_10601677" "prognostic favorable (9.46e-4)" "unprognostic (2.45e-1)" "unprognostic (7.25e-3)" "unprognostic (1.09e-1)" "unprognostic (5.28e-3)" "unprognostic (1.67e-2)" "unprognostic (8.61e-3)" "unprognostic (1.70e-2)" "unprognostic (1.58e-1)" "unprognostic (3.17e-2)" "unprognostic (3.66e-2)" "unprognostic (1.33e-2)" "unprognostic (2.62e-2)" "unprognostic (8.59e-2)" "unprognostic (1.33e-1)" "unprognostic (2.29e-1)" "prognostic favorable (2.84e-4)" 11.0 9.5 5.9 5.5 7.2 21.0 11.1 8.9 6.7 13.5 6.8 12.8 8.8 12.5 7.4 15.3 11.0 5.3 10.4 7.1 5.2 12.2 12.8 8.5 6.9 7.3 6.5 17.2 17.0 4.5 10.3 6.2 7.3 9.3 8.5 52.6 13.4 3.9 9.8 10.2 12.6 5.0 6.7 8.0 10.3 6.9 5.8 5.3 10.9 2.4 6.0 9.6 12.4 10.2 9.2 6.9 17.9 7.1 6.1 4.3 16.4 11.1 4.5 6.6 5.0 7.2 8.1 13.3 5.7 5.6 6.3 9.5 10.8 7.2 8.8 5.9 7.2 10.6 14.3 7.0 2.4 12.6 6.1 4.3 4.3 6.8 5.7 8.5 4.6 7.8 11.7 5.8 7.1 4.0 13.3 9.6 11.2 6.1 8.0 11.1 11.1 3.0 6.2 15.5 11.3 10.9 10.1 10.6 5.0 10.2 7.8 4.2 8.0 9.3 7.7 8.3 8.4 7.2 3.8 8.8 2.7 10.1 5.3 1.0 1.1 1.2 0.9 1.4 0.8 0.9 0.8 0.9 0.7 1.5 0.8 1.0 0.8 2.0 1.5 1.7 0.6 0.4 5.9 7.2 8.9 6.7 7.1 5.2 7.3 6.5 7.3 6.7 5.8 10.2 43.0 22.4 50.9 48.0 40.5 65.1 61.5 43.3 37.0 140.8 35.3 39.0 39.2 28.6 43.4 23.9 373.2 46.4 46.7 81.6 19.6 54.2 5.1 45.0 50.3 43.5 70.3 66.9 29.1 54.8 85.3 35.6 35.2 48.9 51.8 68.4 29.6 35.1 26.1 69.0 35.1 47.8 38.7 19.4 38.2 7.3 43.2 34.0 39.2 28.1 40.9 57.0 28.8 58.8 61.3 47.7 70.6 33.8 33.0 53.8 61.0 19.6 44.6 458.4 26.3 45.0 53.6 58.5 35.8 53.2 45.3 49.4 31.6 71.0 50.0 82.0 ZNF33A "FLJ23404, KIAA0065, KOX31, KOX5, ZNF11A, ZNF33, ZZAPK" ENSG00000189180 "Zinc finger protein 33A" Q06730 10 38010650-38065088 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA005538, HPA056638" Approved Approved "Nucleoli fibrillar center,Endoplasmic reticulum,Vesicles" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoli fibrillar center, Endoplasmic reticulum" Vesicles "HPA005538: , HPA056638: AB_2683199" "unprognostic (1.85e-2)" "unprognostic (1.19e-1)" "unprognostic (7.68e-3)" "unprognostic (1.48e-1)" "unprognostic (3.42e-2)" "unprognostic (1.69e-3)" "unprognostic (7.96e-3)" "unprognostic (4.89e-3)" "unprognostic (6.73e-2)" "unprognostic (9.06e-2)" "unprognostic (2.29e-2)" "unprognostic (3.75e-2)" "unprognostic (2.14e-1)" "unprognostic (1.95e-1)" "unprognostic (3.50e-2)" "unprognostic (6.83e-2)" "unprognostic (7.39e-3)" 9.2 12.6 5.8 12.2 7.0 12.2 17.9 17.1 7.6 14.5 9.6 12.2 13.4 15.1 10.9 9.3 14.9 11.8 9.0 5.0 7.8 15.3 16.3 10.1 14.8 9.5 7.1 14.8 16.9 17.1 14.0 11.4 9.9 15.1 15.8 20.6 14.9 14.3 13.9 13.9 13.7 10.3 6.7 14.2 16.7 4.3 6.8 14.0 15.7 15.8 16.2 11.0 10.3 8.4 16.3 9.1 16.2 14.1 7.8 9.8 12.8 7.3 7.1 9.1 10.2 9.7 14.5 31.5 7.7 9.8 5.2 10.6 19.3 12.6 8.5 18.9 22.0 25.2 18.6 13.2 7.9 36.0 20.2 8.6 22.5 6.9 10.1 17.0 7.5 17.7 13.5 16.5 9.3 10.6 15.0 8.2 16.4 8.2 10.5 12.9 11.2 14.8 12.8 15.0 12.6 19.8 11.3 12.3 6.4 11.2 14.8 9.5 7.3 8.0 11.7 9.0 5.8 13.0 17.1 18.5 7.4 19.7 3.7 12.7 3.6 6.1 5.4 5.0 4.7 6.4 4.7 3.6 3.4 6.2 5.8 4.6 15.9 4.7 6.6 6.3 3.6 3.1 5.8 7.0 17.1 7.6 5.0 7.8 9.5 7.1 9.9 6.7 6.8 8.4 28.4 60.9 73.0 39.8 47.5 11.9 33.0 25.6 19.4 38.2 33.4 28.6 70.6 31.5 49.0 27.6 33.3 28.4 43.1 27.1 25.4 34.9 4.6 62.8 19.3 31.6 34.1 30.3 47.4 29.2 20.0 23.5 25.5 37.7 33.6 47.6 21.4 39.6 19.4 30.3 63.9 28.2 18.3 22.8 16.8 6.7 23.9 26.1 10.6 58.1 46.9 21.1 38.1 56.3 81.5 32.0 29.6 24.0 32.1 38.9 22.0 39.3 80.8 31.8 26.3 32.7 22.7 15.3 18.9 18.7 12.8 35.6 34.6 33.2 27.5 38.4 ZNF33B "KOX2, KOX31, ZNF11B" ENSG00000196693 "Zinc finger protein 33B" Q06732 10 42574185-42638570 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 80.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA005538, HPA056638" Approved Approved "Nucleoli fibrillar center,Endoplasmic reticulum,Vesicles" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nucleoli fibrillar center, Endoplasmic reticulum" Vesicles "HPA005538: , HPA056638: AB_2683199" "unprognostic (3.01e-3)" "unprognostic (2.20e-1)" "unprognostic (2.93e-2)" "unprognostic (8.34e-2)" "unprognostic (5.15e-2)" "unprognostic (1.16e-1)" "unprognostic (1.01e-2)" "unprognostic (2.19e-2)" "unprognostic (1.43e-2)" "unprognostic (1.18e-1)" "unprognostic (3.73e-1)" "unprognostic (3.79e-2)" "unprognostic (2.90e-3)" "unprognostic (3.71e-1)" "unprognostic (1.27e-1)" "unprognostic (5.60e-2)" "unprognostic (1.61e-2)" 4.7 9.8 3.9 5.9 4.9 3.1 20.6 9.8 5.1 9.5 9.5 9.1 8.9 11.7 7.6 7.4 18.6 8.6 5.3 4.8 6.6 18.5 10.3 8.9 9.4 4.9 4.0 23.5 34.1 15.2 10.0 7.2 5.1 12.6 10.4 10.4 18.6 10.4 3.9 12.2 9.7 5.2 2.5 10.3 14.3 4.7 5.3 8.0 18.3 4.9 8.9 9.0 9.0 3.7 13.2 3.3 8.5 8.8 3.1 0.4 10.6 8.1 6.2 5.1 7.1 7.3 14.9 19.9 4.8 3.1 7.7 10.9 16.5 5.6 5.7 11.8 12.4 7.9 12.7 11.9 3.6 18.8 6.2 5.1 20.1 3.1 17.0 13.4 4.4 10.8 10.9 14.7 3.1 5.7 7.5 4.5 9.3 6.5 7.7 8.0 8.5 8.5 13.4 17.2 15.3 14.9 5.1 10.5 5.1 7.7 13.4 5.7 5.3 2.6 12.3 4.5 8.6 9.5 15.5 6.1 1.8 13.9 2.4 19.4 7.5 7.1 10.7 6.7 15.1 20.1 15.4 10.8 6.7 15.4 19.5 13.7 2.4 8.3 5.5 11.1 13.4 9.0 3.9 4.9 9.8 5.1 4.8 6.6 4.9 4.0 5.1 2.5 5.3 3.7 10.0 80.1 37.8 14.0 17.7 4.8 18.0 5.5 18.2 15.4 26.0 27.8 31.5 34.3 30.0 20.2 10.4 18.6 13.4 9.7 21.5 27.0 2.4 37.2 6.0 14.1 25.3 17.1 25.6 36.1 16.8 10.0 14.8 14.5 8.2 23.8 16.4 10.8 8.4 10.1 48.2 17.6 4.1 13.6 3.6 3.8 20.5 9.3 7.2 36.5 17.9 10.2 21.6 30.7 14.1 25.8 21.4 11.7 15.2 13.0 21.2 27.0 47.6 9.6 0.0 9.0 8.5 9.0 11.3 11.8 4.0 11.5 17.0 22.6 18.5 12.8 ZNF341 dJ553F4.3 ENSG00000131061 "Zinc finger protein 341" Q9BYN7 20 33731657-33792269 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 11.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023240, HPA024607, HPA067108" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" Yes No "Cluster 34: Basophils - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Vesicles" "Nuclear bodies" "HPA023240: AB_1859207, HPA024607: AB_1859208, HPA067108: AB_2685780" "unprognostic (1.74e-1)" "unprognostic (2.18e-1)" "unprognostic (3.73e-1)" "unprognostic (2.10e-1)" "unprognostic (9.31e-2)" "prognostic favorable (3.93e-4)" "prognostic unfavorable (1.87e-4)" "unprognostic (2.44e-1)" "unprognostic (1.70e-1)" "unprognostic (1.80e-1)" "unprognostic (7.38e-2)" "unprognostic (9.31e-2)" "unprognostic (8.17e-5)" "unprognostic (4.84e-2)" "unprognostic (2.90e-1)" "unprognostic (8.67e-3)" "unprognostic (3.68e-2)" 1.2 0.9 1.0 1.9 1.1 2.4 0.9 0.8 2.2 1.1 0.0 1.5 1.4 1.3 1.0 1.3 1.3 0.9 1.0 1.6 0.2 0.6 0.6 1.1 1.9 0.3 0.1 1.3 1.6 0.9 0.6 1.4 0.4 1.3 1.1 0.7 1.5 1.0 3.3 2.1 1.0 1.2 0.2 1.9 1.4 1.5 0.5 1.8 0.9 3.3 1.2 1.2 1.1 1.3 2.4 6.4 2.2 4.7 2.1 1.7 9.5 2.3 1.2 1.9 1.2 4.6 5.4 3.7 3.8 1.7 2.2 3.7 2.4 4.1 0.8 3.3 2.2 3.6 3.6 3.7 1.2 2.1 4.3 1.4 3.0 1.6 1.0 1.7 2.3 3.4 1.9 1.7 2.0 2.9 1.9 1.6 3.0 3.5 3.1 2.4 1.4 2.1 1.3 5.2 1.9 2.1 6.1 5.6 1.4 1.7 5.0 1.7 2.9 3.4 1.4 2.5 2.2 1.3 1.9 3.4 3.3 1.7 2.4 2.6 1.3 2.9 1.1 1.8 1.0 2.2 0.8 0.7 1.0 1.2 0.5 1.5 2.5 1.3 1.2 0.7 0.6 0.9 1.0 1.1 0.8 2.2 1.6 0.2 0.3 0.1 0.4 0.2 0.5 1.3 1.8 3.2 5.1 5.5 2.9 0.4 1.0 1.5 0.6 2.2 1.9 1.4 2.7 2.8 4.7 1.8 2.1 2.6 0.9 7.0 0.0 1.5 0.6 1.6 1.4 1.4 1.2 0.8 11.3 1.4 3.3 1.6 6.6 2.1 2.5 1.8 1.4 1.0 1.4 1.7 8.0 2.0 2.0 1.6 2.0 0.1 0.6 2.4 0.0 3.7 1.2 0.6 2.1 6.0 7.7 1.7 2.5 0.4 2.6 2.5 4.2 0.4 4.6 2.3 0.0 1.9 1.1 1.6 2.4 1.6 1.0 2.1 1.9 1.5 2.4 2.5 ZNF365 "KIAA0844, UAN" ENSG00000138311 "Zinc finger protein 365" Q70YC5 10 62374192-62480288 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.7;esophagus: 10.2" "Group enriched" "Detected in some" 6 "Excitatory neurons: 112.7;Oligodendrocyte precursor cells: 113.6;Oligodendrocytes: 195.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "cerebral cortex: 22.7;hippocampal formation: 8.3;thalamus: 8.0;white matter: 16.6" "Group enriched" "Detected in many" 9 "gdT-cell: 2.4;memory CD4 T-cell: 2.1;memory CD8 T-cell: 2.7;naive CD8 T-cell: 2.7;NK-cell: 6.4;T-reg: 5.9" "Group enriched" "Detected in many" 62 "NK-cells: 6.4;T-cells: 5.9" "Cell line enhanced" "Detected in many" "HaCaT: 22.3;PC-3: 13.9;U-251 MG: 18.6;U-87 MG: 12.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052446 Supported Approved Vesicles,Centrosome NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Centrosome" "HPA052446: AB_2681836" "unprognostic (7.46e-2)" "unprognostic (1.42e-1)" "unprognostic (1.36e-1)" "unprognostic (1.26e-3)" "unprognostic (1.21e-1)" "unprognostic (4.05e-3)" "unprognostic (1.73e-1)" "unprognostic (7.67e-2)" "unprognostic (2.15e-2)" "unprognostic (3.11e-3)" "unprognostic (3.06e-2)" "unprognostic (7.90e-2)" "unprognostic (1.12e-6)" "unprognostic (2.49e-3)" "unprognostic (1.58e-1)" "unprognostic (1.20e-4)" "unprognostic (2.89e-2)" 0.1 1.3 1.0 0.1 2.8 0.0 0.3 1.5 22.7 0.9 0.0 0.0 0.1 0.1 0.2 10.2 0.1 0.3 1.0 8.3 0.0 0.1 0.0 0.7 0.0 0.0 3.2 0.0 0.4 5.6 1.6 0.1 0.0 1.8 0.1 5.1 1.1 2.0 0.0 0.8 0.1 0.1 0.0 0.3 0.0 0.5 8.0 0.5 0.6 0.1 1.4 0.8 1.1 16.6 6.3 0.6 0.1 0.0 0.1 0.0 0.0 5.5 5.8 2.6 2.1 0.0 1.0 0.0 0.2 3.1 8.4 22.3 0.0 0.4 3.5 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 7.2 0.9 6.6 0.9 0.0 0.0 0.0 5.5 2.1 0.7 0.0 0.9 0.0 13.9 0.0 0.2 0.0 0.3 2.8 0.1 1.2 1.1 0.2 0.6 0.0 0.0 0.0 0.0 1.1 6.1 0.0 18.6 0.0 0.0 0.0 12.9 0.0 1.8 0.0 0.0 0.0 2.4 0.0 0.0 0.0 2.1 2.7 0.0 0.0 0.4 2.7 0.0 6.4 0.0 0.0 5.9 0.8 1.0 2.8 1.5 22.7 8.3 0.0 0.0 3.2 0.0 0.0 8.0 16.6 0.0 0.0 0.0 15.3 0.2 0.5 3.7 0.6 0.0 13.5 0.3 0.3 2.6 1.5 0.1 3.7 2.1 0.0 2.8 0.0 0.0 0.2 0.5 0.3 0.2 0.2 0.0 0.0 112.7 0.0 0.0 0.9 0.0 0.6 0.0 0.1 0.0 0.0 0.1 18.5 23.4 0.0 0.0 0.3 1.1 0.3 0.0 0.4 0.0 6.5 0.0 2.7 0.0 113.6 195.5 0.9 0.0 0.0 1.9 1.2 0.0 0.7 0.1 5.3 0.0 0.8 0.8 0.1 0.7 0.0 0.4 0.0 3.9 0.2 0.0 6.0 ZNF37A "KOX21, ZNF37" ENSG00000075407 "Zinc finger protein 37A" P17032 10 38094334-38150293 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003172 Approved Approved Vesicles NA NA "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "HPA003172: AB_1080709" "unprognostic (8.64e-2)" "unprognostic (1.24e-1)" "unprognostic (3.22e-1)" "unprognostic (6.87e-2)" "unprognostic (1.17e-2)" "unprognostic (2.31e-2)" "prognostic unfavorable (2.83e-4)" "unprognostic (7.65e-3)" "unprognostic (2.47e-1)" "unprognostic (3.54e-2)" "unprognostic (1.02e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (2.31e-4)" "unprognostic (4.39e-2)" "unprognostic (1.29e-1)" "unprognostic (3.43e-2)" "unprognostic (3.09e-2)" 4.9 5.6 5.9 6.2 6.0 3.1 5.7 11.3 7.8 6.3 4.3 5.6 4.8 7.2 5.8 3.7 5.2 4.5 4.3 6.3 8.0 5.8 4.9 4.8 5.9 5.5 5.0 7.5 8.7 9.7 8.6 4.8 5.9 5.7 4.8 16.6 7.6 5.6 3.7 6.3 4.6 5.6 3.6 6.0 5.6 2.4 6.7 5.8 8.1 5.1 6.0 4.4 4.2 8.8 15.8 7.9 7.0 13.2 10.5 10.2 7.6 11.9 4.5 5.4 7.2 6.4 4.5 23.1 3.5 6.6 7.4 6.3 13.2 10.0 8.4 14.9 12.5 23.3 9.7 9.1 9.0 24.7 14.4 7.8 16.4 9.3 7.7 10.8 7.2 10.8 15.4 15.9 11.7 3.7 14.0 3.7 6.1 5.5 13.0 10.0 19.0 4.6 5.7 6.1 5.6 9.6 8.2 6.6 6.7 7.4 12.1 7.6 12.4 10.1 10.9 9.8 11.6 17.8 20.5 8.9 6.7 17.3 6.5 1.3 1.0 1.0 1.5 0.8 2.0 1.5 1.8 1.6 1.0 2.6 2.1 1.8 0.7 2.7 2.3 1.2 1.1 0.7 5.9 6.0 11.3 7.8 6.3 8.0 5.5 5.0 5.9 3.6 6.7 8.8 21.8 25.6 43.6 31.6 26.0 8.2 14.7 11.0 18.8 66.1 14.4 16.4 29.6 15.7 18.8 11.0 54.2 10.2 23.2 7.6 1.9 18.1 3.7 15.0 30.0 26.3 41.9 26.3 46.7 11.8 6.8 27.0 16.3 14.9 40.5 56.9 22.9 10.4 7.1 42.1 57.7 10.4 10.2 11.3 6.4 1.4 28.3 13.8 5.4 40.3 16.6 27.4 30.9 64.3 85.5 11.9 8.3 28.2 34.4 17.0 12.6 7.3 12.6 55.1 13.1 53.5 25.7 22.2 15.2 14.7 6.0 3.8 18.5 48.5 12.5 9.3 ZNF442 FLJ14356 ENSG00000198342 "Zinc finger protein 442" Q9H7R0 19 12345944-12365905 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 10.0" "Cell type enhanced" "Detected in many" "Adipocytes: 7.7;Granulosa cells: 7.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/84: 5.5" "HPA045738, HPA053407" Uncertain Approved "Nuclear membrane,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 40: Granulosa cells - Unknown function" "Nuclear membrane" Vesicles "HPA045738: AB_10968057, HPA053407: AB_2682138" "unprognostic (2.61e-2)" "unprognostic (3.32e-2)" "unprognostic (1.59e-1)" "unprognostic (7.36e-2)" "unprognostic (1.28e-1)" "unprognostic (5.53e-2)" "unprognostic (6.64e-2)" "unprognostic (2.07e-2)" "unprognostic (3.17e-3)" "unprognostic (1.35e-1)" "unprognostic (7.52e-3)" "unprognostic (1.78e-1)" "unprognostic (1.91e-3)" "unprognostic (1.38e-1)" "unprognostic (1.30e-1)" "unprognostic (5.80e-2)" "unprognostic (1.99e-2)" 1.6 1.0 2.5 1.0 4.3 0.5 1.7 3.4 2.3 1.8 5.7 1.1 0.6 1.9 1.1 0.9 2.1 0.6 1.2 2.0 4.5 2.1 2.0 1.2 1.3 10.0 6.0 4.9 1.7 1.3 0.9 1.0 7.7 1.7 1.3 1.2 0.9 2.1 0.8 1.3 0.8 1.6 3.9 1.7 0.9 1.3 6.1 1.2 2.0 1.5 1.0 1.8 1.5 5.3 0.2 0.0 1.7 2.2 1.0 0.5 0.1 2.3 0.6 2.0 1.6 1.6 0.5 2.0 0.7 1.2 0.8 0.4 1.4 1.1 1.9 0.0 0.2 0.1 3.2 1.5 0.8 0.0 1.9 0.9 1.2 0.8 0.3 0.1 0.2 1.4 2.9 0.2 1.8 1.5 2.4 0.3 1.4 0.3 1.0 0.1 2.5 0.1 0.8 1.3 0.1 0.4 0.0 0.0 0.0 1.9 2.2 1.5 0.0 2.6 1.3 3.3 1.4 2.0 5.5 0.0 0.1 0.0 1.0 0.5 0.3 2.2 0.8 0.5 0.5 2.5 0.5 0.5 0.5 0.4 1.3 0.8 0.6 0.4 0.4 0.5 0.0 0.3 2.5 4.3 3.4 2.3 2.0 4.5 10.0 6.0 7.7 3.9 6.1 5.3 7.7 0.0 2.6 1.0 2.4 0.4 1.1 2.2 1.8 1.6 1.9 1.9 2.8 1.5 0.6 1.8 6.2 0.4 1.6 0.7 1.9 0.9 1.0 0.9 1.6 3.2 1.2 0.4 0.9 0.9 0.4 2.5 0.0 1.2 2.5 7.0 3.6 1.6 1.5 0.0 1.5 0.7 2.0 2.4 0.6 0.5 0.6 1.5 3.6 1.9 1.6 2.2 3.1 0.5 1.3 0.2 0.1 0.4 2.7 0.8 0.3 3.7 1.8 1.7 0.0 4.8 3.9 2.4 2.5 1.2 0.6 0.4 1.3 0.6 0.5 0.6 ZNF511 "MGC30006, Zfp511" ENSG00000198546 "Zinc finger protein 511" Q8NB15 10 133308914-133313162 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035360 Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" "Intracellular and membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Nuclear bodies" "Nucleoplasm, Vesicles" "HPA035360: AB_10601931" "unprognostic (3.35e-2)" "unprognostic (2.19e-1)" "unprognostic (1.91e-1)" "unprognostic (8.84e-2)" "unprognostic (1.31e-1)" "unprognostic (1.16e-1)" "unprognostic (3.04e-1)" "unprognostic (1.68e-2)" "unprognostic (2.75e-1)" "unprognostic (1.64e-2)" "unprognostic (1.40e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.94e-2)" "unprognostic (3.91e-2)" "unprognostic (2.55e-1)" "unprognostic (4.52e-2)" 12.7 11.6 15.9 8.7 16.2 17.1 11.3 15.5 17.2 15.8 17.5 19.7 16.1 15.7 10.7 10.8 15.4 9.4 21.2 15.4 15.4 10.4 21.3 11.4 12.6 16.7 15.9 20.4 15.5 14.7 12.7 8.7 15.7 16.1 12.8 5.8 16.7 10.7 49.1 7.9 13.2 11.1 16.4 12.5 12.5 9.6 16.8 11.4 10.9 31.9 9.7 13.6 12.5 16.5 54.1 54.0 30.3 43.8 25.6 21.6 32.6 25.2 39.3 53.3 44.4 88.0 50.9 48.2 24.4 29.5 33.9 48.8 41.9 36.0 23.2 38.8 92.1 29.1 22.1 53.4 21.0 57.5 52.1 22.0 19.2 43.7 26.5 30.6 24.3 22.7 40.0 22.4 18.6 71.2 27.5 76.1 37.3 50.2 74.6 37.1 37.1 12.4 28.3 18.6 16.9 37.0 16.8 30.0 38.2 18.7 23.2 33.1 23.3 23.1 35.4 26.5 68.5 31.3 36.4 66.1 37.5 26.8 12.9 40.2 61.1 68.6 45.4 52.6 35.6 66.6 37.0 46.6 61.0 51.8 41.6 40.8 8.5 41.0 51.1 65.9 36.2 47.3 15.9 16.2 15.5 17.2 15.4 15.4 16.7 15.9 15.7 16.4 16.8 16.5 16.3 16.0 14.5 7.5 33.6 29.6 45.6 40.7 39.3 19.5 37.3 52.6 23.6 25.8 21.9 22.0 8.4 61.2 36.7 33.3 70.5 39.5 29.5 18.5 22.4 20.9 53.4 40.2 10.7 41.2 62.9 34.0 20.4 15.2 78.1 40.6 20.3 54.4 47.4 21.9 7.6 128.8 22.4 33.9 38.0 8.8 41.7 39.9 16.0 5.6 64.3 27.4 41.2 3.5 12.3 38.6 44.0 30.5 40.4 43.0 60.8 72.1 23.2 23.6 26.3 27.3 34.5 58.1 48.0 36.3 35.9 28.2 33.0 38.6 65.9 41.5 ZNF511-PRAP1 ENSG00000283496 "ZNF511-PRAP1 readthrough" 10 133309410-133352529 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "intestine: 9.2;kidney: 8.4;liver: 30.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 1.3;RPMI-8226: 1.0" "HPA035360, HPA038713, HPA052451" Supported Uncertain "Nucleoplasm,Nuclear bodies,Vesicles" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Nuclear bodies" "Nucleoplasm, Vesicles" "HPA035360: AB_10601931, HPA038713: AB_10673117, HPA052451: AB_2681839" 0.2 0.1 0.0 1.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 6.2 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 30.4 0.0 0.4 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.1 0.0 9.2 0.0 0.1 0.0 0.2 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.3 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.1 0.1 1.0 0.0 0.1 0.0 0.7 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZNF526 "KIAA1951, MGC4267" ENSG00000167625 "Zinc finger protein 526" Q8TF50 19 42220312-42228201 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 33.3;granulocytes: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023070, HPA056609" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA023070: AB_2671057, HPA056609: AB_2683189" "unprognostic (2.04e-1)" "unprognostic (3.15e-1)" "unprognostic (2.42e-1)" "unprognostic (3.95e-3)" "unprognostic (1.46e-1)" "unprognostic (5.86e-2)" "unprognostic (9.09e-3)" "unprognostic (1.79e-1)" "unprognostic (8.84e-2)" "unprognostic (8.62e-3)" "unprognostic (1.28e-2)" "unprognostic (2.14e-1)" "unprognostic (1.59e-1)" "unprognostic (1.98e-1)" "unprognostic (1.35e-1)" "unprognostic (2.81e-1)" "unprognostic (2.30e-1)" 3.4 2.5 2.1 2.8 2.3 3.8 3.1 4.3 2.6 3.9 2.0 3.3 3.3 3.6 2.3 3.1 3.5 1.9 2.8 2.0 2.1 2.3 2.8 2.6 4.0 2.4 2.2 4.5 3.5 3.9 3.0 3.0 2.3 3.3 2.1 2.0 4.6 3.3 5.1 5.2 3.1 2.4 1.6 3.6 3.1 3.5 2.4 4.2 2.8 4.0 3.6 3.5 3.4 3.4 7.8 24.8 7.1 6.4 8.0 7.7 6.2 8.9 8.2 9.2 10.1 13.0 5.5 12.6 6.3 9.5 4.2 5.7 7.7 9.7 5.7 7.5 9.2 12.6 12.0 12.5 7.5 8.1 7.8 7.6 7.7 9.2 9.6 5.7 5.8 6.7 12.3 7.8 5.9 10.8 8.2 5.2 4.7 6.8 8.7 9.4 8.7 5.7 4.2 14.0 7.3 6.4 10.2 10.1 7.2 5.4 4.1 14.4 7.8 11.3 7.7 4.8 11.2 9.3 5.9 8.5 7.5 7.8 9.5 1.8 3.6 1.4 4.5 3.6 6.9 4.7 3.5 4.1 2.8 4.4 4.2 5.3 0.7 3.4 5.3 4.2 3.9 3.3 2.1 2.3 4.3 2.6 2.0 2.1 2.4 2.2 2.3 1.6 2.4 3.4 3.0 22.4 33.3 2.0 6.9 5.5 4.4 2.8 4.0 7.4 3.1 2.4 3.2 0.0 17.1 3.7 14.6 8.0 3.2 5.7 3.9 4.1 5.8 1.7 4.0 7.1 13.8 9.5 1.4 3.0 8.3 7.4 4.6 2.3 25.2 4.9 3.6 2.6 4.6 6.7 1.5 4.2 2.0 6.8 1.8 6.3 7.2 7.0 0.0 1.9 5.8 4.1 11.3 1.0 1.4 2.9 2.8 3.0 6.1 4.6 7.8 2.8 9.2 9.6 0.0 5.7 3.6 9.9 10.1 1.9 5.1 10.3 6.7 3.7 5.7 2.6 ZNF530 KIAA1508 ENSG00000183647 "Zinc finger protein 530" Q6P9A1 19 57599885-57612722 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 8.6;Muller glia cells: 9.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "HEK 293: 75.0;U-266/84: 58.8" HPA045868 Uncertain Approved Vesicles NA NA "Cluster 37: B-cells - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" Vesicles "HPA045868: AB_2679478" "unprognostic (1.57e-1)" "unprognostic (3.02e-3)" "unprognostic (5.65e-2)" "unprognostic (2.90e-2)" "unprognostic (3.58e-2)" "unprognostic (1.06e-1)" "unprognostic (1.54e-2)" "unprognostic (6.80e-2)" "unprognostic (9.69e-3)" "unprognostic (4.98e-3)" "unprognostic (3.19e-2)" "unprognostic (7.84e-3)" "unprognostic (1.47e-1)" "unprognostic (1.70e-1)" "unprognostic (3.11e-1)" "unprognostic (1.86e-2)" "unprognostic (1.06e-1)" 1.5 1.4 4.5 1.2 4.2 3.2 1.6 6.8 5.4 0.7 5.6 1.1 1.0 1.0 1.9 0.9 0.7 0.7 4.0 4.6 4.2 1.1 0.8 0.9 2.0 4.3 3.7 0.9 1.5 0.8 0.7 1.2 4.0 1.4 0.8 2.6 1.2 1.4 6.3 2.2 1.0 0.7 3.8 2.2 1.8 1.2 4.0 2.3 1.0 2.7 2.3 1.0 0.7 4.8 6.7 5.8 4.3 3.7 0.3 1.9 6.8 4.1 1.7 6.8 3.8 4.1 1.0 0.8 3.3 1.5 4.1 2.2 3.6 3.0 7.2 0.2 75.0 13.4 11.6 2.6 0.5 4.9 6.1 1.3 1.7 6.4 1.8 1.9 1.5 4.7 1.7 3.0 2.3 2.6 7.0 3.8 6.4 0.5 14.2 0.9 13.6 6.3 1.3 11.3 4.9 4.5 4.8 1.2 1.4 3.8 3.1 7.6 2.0 8.5 5.3 1.9 8.5 14.6 58.8 9.3 5.2 5.2 6.0 1.0 1.5 1.0 3.0 0.9 2.2 3.5 2.0 3.1 1.8 2.5 2.7 2.2 1.7 3.1 1.1 1.7 2.9 1.6 4.5 4.2 6.8 5.4 4.6 4.2 4.3 3.7 4.0 3.8 4.0 4.8 2.7 6.4 1.5 1.6 2.3 1.8 0.7 1.7 1.8 3.3 1.8 1.0 8.6 1.5 0.9 0.0 0.0 2.0 3.1 0.6 1.9 1.9 0.3 0.9 0.8 2.7 0.0 4.0 1.4 2.9 1.5 1.4 1.1 0.8 2.5 2.2 2.9 0.7 2.0 0.0 1.0 0.2 2.0 0.8 2.0 0.3 0.9 0.6 5.4 0.0 1.5 9.1 2.1 0.5 0.9 1.4 1.7 1.5 2.5 1.3 0.9 0.8 0.7 4.2 6.6 1.5 1.7 2.1 2.9 1.6 1.7 1.4 2.3 1.1 1.0 0.9 ZNF540 DKFZp547B0714 ENSG00000171817 "Zinc finger protein 540" Q8NDQ6 19 37551406-37614179 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 25.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 23.3;Excitatory neurons: 47.7;Inhibitory neurons: 56.5;Oligodendrocyte precursor cells: 23.1;Oligodendrocytes: 27.7;Rod photoreceptor cells: 22.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 2.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 3.0" HPA003444 Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 32: T-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Vesicles, Cytosol" "HPA003444: AB_1080732" "unprognostic (2.51e-2)" "unprognostic (2.30e-4)" "unprognostic (4.92e-2)" "unprognostic (1.12e-1)" "unprognostic (2.80e-4)" "unprognostic (4.24e-4)" "unprognostic (3.44e-3)" "unprognostic (8.88e-4)" "unprognostic (2.65e-1)" "unprognostic (3.17e-1)" "unprognostic (3.38e-5)" "unprognostic (1.50e-1)" "unprognostic (1.09e-6)" "unprognostic (2.74e-1)" "unprognostic (4.75e-2)" "unprognostic (8.08e-2)" "unprognostic (8.33e-5)" 1.6 4.9 10.5 2.3 10.2 0.6 3.1 14.4 11.2 5.0 6.8 4.4 2.1 3.3 4.8 1.6 3.9 1.8 5.3 9.4 12.3 5.0 2.2 2.6 3.8 8.2 8.9 8.5 2.5 5.3 14.7 1.1 8.6 5.5 1.8 25.8 3.5 4.6 2.0 3.2 4.2 1.8 7.9 4.7 3.2 2.9 11.4 2.1 7.9 1.6 3.4 3.6 3.4 9.1 0.1 0.0 1.1 1.3 3.0 1.8 0.1 0.4 0.4 0.5 0.9 0.1 0.0 0.5 0.1 1.1 0.3 0.4 0.8 0.4 0.4 1.7 1.2 0.4 0.8 0.0 0.8 0.5 0.9 0.9 1.1 0.3 0.0 0.2 0.0 2.4 0.2 0.0 0.7 0.0 0.8 0.3 0.4 0.1 0.2 0.7 0.7 0.4 0.2 0.1 1.2 1.4 0.4 0.1 0.1 0.8 0.6 0.5 0.0 0.4 1.4 0.5 0.4 1.6 1.0 1.3 0.0 0.2 0.2 0.0 0.0 0.8 2.7 0.0 2.6 1.9 2.7 3.0 0.1 2.2 4.4 4.8 0.1 2.4 0.0 0.2 3.1 1.2 10.5 10.2 14.4 11.2 9.4 12.3 8.2 8.9 8.6 7.9 11.4 9.1 2.3 3.2 2.6 15.3 6.3 1.7 1.3 0.8 3.4 23.3 2.4 2.2 10.4 0.0 1.7 1.8 6.2 0.3 3.3 0.2 7.9 0.3 18.6 1.1 1.0 2.2 0.0 0.0 47.7 0.4 0.4 2.8 1.5 0.6 3.8 1.7 2.2 1.1 0.8 18.5 56.5 0.3 0.0 0.8 1.0 5.5 2.5 1.0 3.6 11.2 0.5 5.5 8.2 23.1 27.7 0.2 1.1 5.7 2.5 0.4 2.3 2.7 0.4 22.3 6.6 3.1 2.9 5.7 3.3 1.8 1.3 0.1 3.9 1.2 0.3 0.2 ZNF550 MGC41917 ENSG00000251369 "Zinc finger protein 550" Q7Z398 19 57535257-57559863 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003251 Uncertain Approved Vesicles,Microtubules NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 29: U-266 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Vesicles Microtubules "HPA003251: AB_1080736" "unprognostic (3.09e-1)" "unprognostic (1.92e-1)" "unprognostic (2.06e-1)" "unprognostic (2.38e-2)" "unprognostic (1.43e-1)" "unprognostic (2.15e-2)" "unprognostic (1.40e-2)" "unprognostic (3.61e-2)" "unprognostic (2.66e-3)" "unprognostic (3.46e-1)" "unprognostic (4.09e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (8.33e-2)" "unprognostic (1.59e-1)" "unprognostic (2.69e-2)" "unprognostic (6.68e-3)" "unprognostic (1.52e-1)" 2.8 3.7 1.8 5.1 2.0 5.2 6.0 5.8 2.7 5.5 3.2 2.8 2.2 4.6 3.9 3.1 4.6 3.1 5.6 1.7 2.9 2.9 3.0 3.4 6.7 1.5 1.8 9.1 2.4 7.8 2.5 6.5 2.3 6.0 2.9 7.3 4.2 4.4 2.2 4.0 3.6 3.3 1.1 7.7 3.5 2.8 1.7 7.4 4.8 3.3 5.4 3.6 1.3 2.9 4.3 3.0 8.4 8.0 2.8 6.9 0.0 5.7 4.8 5.0 2.1 3.7 3.9 1.2 3.9 4.2 4.0 3.6 4.4 5.0 6.3 0.1 23.2 11.5 10.9 4.9 4.1 10.1 4.3 5.8 3.0 3.9 11.2 6.9 4.2 10.6 1.8 0.1 5.4 1.0 15.5 4.4 9.2 1.3 5.8 12.3 8.7 12.1 2.7 7.6 7.8 11.0 7.2 4.8 3.5 5.9 5.5 6.6 4.8 6.9 4.2 2.6 5.6 24.0 24.0 10.0 2.8 5.8 6.1 0.4 1.4 2.0 3.6 1.9 4.5 1.8 4.5 2.5 2.0 2.6 5.8 3.4 0.4 5.2 0.6 0.7 4.5 2.3 1.8 2.0 5.8 2.7 1.7 2.9 1.5 1.8 2.3 1.1 1.7 2.9 4.5 0.0 1.1 4.2 8.9 5.1 3.9 2.6 5.7 4.5 4.7 3.6 7.2 2.8 3.4 0.0 6.2 4.2 4.9 0.5 1.9 2.8 1.0 3.4 4.7 5.8 3.6 5.0 4.8 1.2 4.4 3.9 0.5 2.9 5.1 8.3 5.0 3.2 2.3 11.8 5.3 2.8 4.1 1.9 2.2 0.6 4.7 1.4 3.6 2.8 2.5 3.0 12.3 4.0 3.7 2.2 0.8 0.7 3.4 6.7 1.2 0.9 6.5 5.1 0.0 3.3 4.4 3.2 5.0 4.4 6.8 5.2 6.2 4.4 2.7 4.3 ZNF563 FLJ34797 ENSG00000188868 "Zinc finger protein 563" Q8TA94 19 12317477-12333720 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 14.5" "Cell type enriched" "Detected in many" 6 "Early spermatids: 200.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 4.2;T-cells: 8.9" "Cell line enhanced" "Detected in many" "Hep G2: 9.0" HPA042136 Uncertain Approved Vesicles NA NA "Cluster 32: T-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA042136: AB_10795395" "unprognostic (1.40e-1)" "unprognostic (3.61e-1)" "unprognostic (1.02e-1)" "unprognostic (8.81e-2)" "unprognostic (9.88e-2)" "unprognostic (2.49e-1)" "unprognostic (1.20e-1)" "unprognostic (9.16e-4)" "unprognostic (1.02e-2)" "unprognostic (5.38e-2)" "unprognostic (3.36e-2)" "unprognostic (1.51e-1)" "unprognostic (2.29e-3)" "unprognostic (9.90e-2)" "unprognostic (2.12e-1)" "unprognostic (1.27e-3)" "unprognostic (1.18e-2)" 2.5 2.8 1.9 2.0 1.9 1.1 3.8 3.1 1.9 3.3 1.6 2.1 1.4 2.1 2.2 2.4 3.1 1.5 3.9 1.9 1.2 3.8 10.0 1.9 2.8 1.7 1.4 3.5 2.1 2.5 2.2 1.1 1.8 4.9 2.1 2.7 2.7 2.6 1.9 3.9 2.2 2.0 0.9 2.6 1.8 14.5 1.8 3.0 5.5 3.0 3.0 2.7 3.2 2.7 2.0 0.2 0.7 2.7 2.8 1.8 0.2 2.3 4.5 2.8 4.1 2.6 0.7 4.6 2.4 2.9 3.1 1.6 2.4 5.4 2.5 0.1 0.4 0.6 0.5 9.0 2.2 0.4 2.8 3.0 3.7 2.8 1.9 2.1 0.1 2.5 0.9 1.0 2.5 1.3 2.5 0.9 1.1 1.0 2.0 0.1 2.0 0.1 3.0 2.7 0.7 1.3 0.3 0.5 0.3 3.1 2.2 0.2 0.3 4.4 0.8 5.1 1.4 4.4 3.8 0.3 0.8 0.4 1.6 0.8 1.1 0.7 2.7 1.2 1.6 3.2 4.6 2.5 1.4 4.2 8.9 5.2 0.8 1.5 1.4 1.4 3.9 2.2 1.9 1.9 3.1 1.9 1.9 1.2 1.7 1.4 1.8 0.9 1.8 2.7 3.2 3.2 1.7 2.3 4.6 1.3 2.0 3.0 4.6 8.4 2.4 3.4 5.5 5.7 2.1 1.8 0.0 0.3 2.6 1.1 1.9 4.7 200.4 3.6 2.3 3.7 0.0 19.4 4.2 4.9 0.2 2.6 2.0 2.0 0.0 9.5 3.3 8.3 2.2 5.0 2.6 2.4 2.0 1.9 0.4 32.3 7.8 1.7 5.4 3.7 1.8 13.9 8.2 3.5 2.7 2.6 4.5 5.7 1.5 2.0 2.6 7.8 4.9 3.4 13.1 3.1 3.3 15.8 6.3 2.8 2.0 0.1 4.7 3.3 2.5 0.9 ZNF569 "FLJ32053, ZAP1, Zfp74" ENSG00000196437 "Zinc finger protein 569" Q5MCW4 19 37411155-37469275 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 137.7;Late spermatids: 41.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052994 Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Golgi apparatus, Vesicles" "HPA052994: AB_2682007" "unprognostic (1.40e-1)" "unprognostic (3.37e-1)" "unprognostic (4.95e-2)" "unprognostic (2.18e-2)" "unprognostic (5.44e-2)" "unprognostic (4.79e-2)" "unprognostic (2.95e-2)" "unprognostic (4.00e-1)" "unprognostic (5.08e-2)" "unprognostic (6.50e-3)" "unprognostic (4.01e-3)" "unprognostic (9.41e-2)" "unprognostic (9.70e-2)" "unprognostic (3.04e-2)" "unprognostic (5.77e-2)" "unprognostic (1.91e-2)" "unprognostic (1.37e-1)" 3.3 4.1 4.0 2.8 4.1 4.6 3.5 7.2 4.5 3.3 4.0 2.2 1.7 3.8 4.7 2.2 3.3 2.3 4.3 3.3 5.9 3.5 3.3 2.5 4.0 3.6 4.8 5.6 1.8 4.5 3.3 3.0 4.2 2.9 1.8 13.7 2.3 2.8 4.4 3.2 1.8 3.4 3.6 3.4 2.3 10.9 5.8 5.1 5.6 4.7 3.2 2.2 1.8 6.5 3.3 6.2 7.6 12.2 6.0 5.5 3.7 5.9 3.4 6.1 6.5 2.3 1.5 4.0 8.4 4.5 6.0 1.2 8.4 2.0 6.6 9.0 5.1 10.3 1.8 3.8 3.6 1.9 4.0 3.8 1.4 6.3 0.2 6.3 5.2 11.7 3.3 0.8 8.7 2.0 12.0 4.1 8.0 0.2 4.4 8.1 9.6 4.1 4.4 3.3 6.4 9.8 0.2 1.3 3.4 7.1 5.3 8.1 5.3 4.9 10.1 3.9 9.6 10.2 18.6 15.0 0.2 4.2 7.8 3.7 1.8 5.9 6.4 2.6 5.5 4.6 5.7 6.1 2.2 5.4 8.0 6.5 1.8 4.8 3.3 2.4 6.1 2.4 4.0 4.1 7.2 4.5 3.3 5.9 3.6 4.8 4.2 3.6 5.8 6.5 5.1 0.0 1.7 14.0 7.8 1.7 1.7 2.0 2.8 16.1 3.5 4.2 16.3 0.0 5.2 1.8 31.3 3.2 8.1 0.5 1.9 1.5 137.7 5.1 3.9 6.5 0.0 2.1 14.5 2.0 4.0 4.0 1.5 2.3 2.5 5.3 5.3 2.5 2.9 3.3 17.4 0.4 0.0 3.8 3.9 41.8 4.7 4.0 0.0 8.4 3.0 9.3 8.2 20.6 23.4 1.6 0.4 7.5 2.4 0.9 1.0 4.7 5.3 30.2 0.0 6.9 6.3 32.3 13.1 3.4 2.0 0.8 9.1 4.2 0.7 0.9 ZNF574 FLJ22059 ENSG00000105732 "Zinc finger protein 574" Q6ZN55 19 42068477-42081552 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 40.9;Spermatocytes: 35.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023196, HPA057274" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 71: Testis - DNA repair" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Transcription" Nucleoplasm Vesicles "HPA023196: AB_2671105, HPA057274: AB_2683392" "unprognostic (3.90e-1)" "unprognostic (3.68e-2)" "unprognostic (3.39e-2)" "unprognostic (7.84e-2)" "unprognostic (1.66e-1)" "unprognostic (2.11e-2)" "unprognostic (9.49e-2)" "unprognostic (2.84e-2)" "unprognostic (5.24e-2)" "unprognostic (1.55e-3)" "unprognostic (6.36e-3)" "unprognostic (2.11e-1)" "unprognostic (2.10e-2)" "unprognostic (6.48e-2)" "unprognostic (3.51e-2)" "unprognostic (2.97e-1)" "unprognostic (1.09e-3)" 8.1 5.4 6.8 4.6 6.1 11.1 7.9 9.5 7.7 8.4 4.3 9.5 6.7 10.3 2.7 9.6 8.8 5.1 6.8 6.2 6.2 5.5 5.4 5.6 6.5 6.9 5.8 9.6 7.9 6.1 6.5 5.0 5.8 7.5 2.8 4.1 8.1 6.7 9.3 12.8 7.5 3.7 5.6 8.4 7.2 27.1 6.3 6.3 6.0 6.4 4.2 8.2 7.5 6.3 15.0 41.1 9.0 11.4 8.1 8.0 9.7 11.0 9.6 14.2 13.6 16.2 10.1 21.4 9.7 9.1 7.5 8.9 10.4 14.1 5.6 11.4 17.6 20.5 10.1 14.0 8.6 12.6 13.5 9.5 13.9 13.2 11.1 8.7 7.9 11.8 17.1 13.3 10.1 31.2 15.2 10.9 16.1 13.5 16.2 20.7 8.6 9.3 7.4 19.7 14.9 12.8 11.3 24.0 7.3 6.2 11.0 20.5 9.5 19.2 14.9 5.8 16.4 14.3 9.3 15.7 10.6 11.9 11.0 12.3 10.5 16.7 16.2 7.8 17.6 17.3 12.1 17.8 12.5 12.8 12.6 11.9 13.3 10.9 11.2 11.1 10.3 12.9 6.8 6.1 9.5 7.7 6.2 6.2 6.9 5.8 5.8 5.6 6.3 6.3 6.0 0.0 3.3 1.3 11.3 29.3 15.1 6.1 40.9 7.5 11.0 7.6 4.3 4.3 6.0 1.8 2.1 7.9 6.3 5.8 1.9 6.9 25.3 6.1 5.7 7.6 3.5 8.6 1.4 5.1 6.7 6.6 7.7 5.7 12.7 5.4 6.8 3.1 5.1 3.3 1.7 7.6 6.1 2.5 11.0 15.7 5.6 3.0 8.8 1.0 7.5 3.9 4.1 1.5 0.9 4.3 8.5 8.6 8.1 10.6 6.4 4.3 5.2 9.8 6.6 8.8 8.0 35.5 20.5 22.1 22.7 4.8 10.6 3.8 7.9 9.6 ZNF586 FLJ20070 ENSG00000083828 "Zinc finger protein 586" Q9NXT0 19 57769655-57819939 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 4 "cerebellum: 18.9" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA030306, HPA060782" Approved Approved "Nucleoli fibrillar center,Vesicles" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 57: B-cells - Immune response" "Nucleoli fibrillar center" Vesicles "HPA030306: AB_2673423, HPA060782: AB_2684362" "prognostic favorable (9.83e-5)" "unprognostic (1.60e-2)" "unprognostic (2.93e-1)" "unprognostic (1.72e-3)" "unprognostic (2.52e-2)" "unprognostic (2.60e-1)" "unprognostic (1.10e-2)" "unprognostic (1.02e-3)" "unprognostic (3.22e-3)" "unprognostic (2.06e-2)" "unprognostic (1.88e-1)" "unprognostic (2.99e-2)" "unprognostic (1.72e-2)" "unprognostic (6.01e-2)" "unprognostic (1.47e-1)" "unprognostic (1.02e-1)" "prognostic favorable (5.36e-4)" 5.2 4.3 3.6 6.3 4.0 25.4 6.9 18.9 4.1 6.1 5.9 5.6 5.9 5.9 5.0 6.6 5.9 4.9 6.0 3.6 4.6 5.3 4.8 5.8 11.8 2.4 2.2 9.0 6.5 4.2 4.8 6.9 2.0 8.4 5.9 9.3 8.9 4.1 9.7 8.3 6.5 5.8 0.3 10.4 7.2 5.0 3.0 13.4 6.2 7.2 9.8 6.5 7.2 4.3 7.2 6.0 8.6 9.6 4.1 3.7 14.4 5.0 5.3 7.0 3.8 2.8 7.2 16.1 0.4 4.6 6.6 4.7 1.6 7.2 13.1 2.4 30.9 12.2 15.1 1.6 7.5 12.0 10.4 6.4 7.5 5.2 7.6 7.9 8.5 15.6 8.0 0.7 8.3 1.7 12.3 8.2 12.8 4.8 17.3 11.9 3.2 20.2 8.3 17.8 11.9 5.9 2.3 7.4 5.8 7.4 7.1 7.6 4.6 9.2 5.1 0.3 8.8 15.4 23.0 17.1 5.0 1.3 6.6 8.0 9.6 31.5 8.4 8.0 8.2 7.0 10.8 8.9 8.9 9.7 13.3 12.2 29.5 10.1 5.4 6.6 15.1 7.3 3.6 4.0 18.9 4.1 3.6 4.6 2.4 2.2 2.0 0.3 3.0 4.3 3.9 0.0 1.5 3.6 13.6 12.1 7.9 6.6 9.6 3.6 4.9 4.2 4.8 0.0 3.3 3.7 0.0 7.1 8.5 2.1 9.8 3.4 0.9 4.3 2.8 4.5 3.0 4.4 4.0 2.0 6.9 3.4 2.6 5.7 3.8 8.6 5.0 3.5 5.5 6.7 4.7 4.0 8.2 8.2 6.8 1.1 0.9 5.6 3.6 1.9 7.1 3.1 6.2 3.0 3.4 2.1 1.7 2.6 9.2 3.6 4.4 5.9 2.2 5.2 6.6 2.6 3.8 10.4 8.7 7.0 11.4 10.0 9.2 4.5 4.0 8.5 ZNF605 ENSG00000196458 "Zinc finger protein 605" Q86T29 12 132918306-132956306 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA061970, HPA062655" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm Vesicles "HPA061970: AB_2684649, HPA062655: AB_2684820" "unprognostic (2.38e-1)" "unprognostic (2.58e-1)" "unprognostic (3.44e-2)" "unprognostic (2.98e-2)" "unprognostic (6.38e-2)" "unprognostic (3.83e-2)" "unprognostic (1.16e-6)" "unprognostic (3.62e-1)" "unprognostic (1.15e-1)" "unprognostic (4.03e-1)" "unprognostic (2.13e-2)" "unprognostic (1.10e-2)" "unprognostic (2.89e-1)" "unprognostic (6.58e-2)" "unprognostic (1.10e-1)" "unprognostic (7.53e-2)" "unprognostic (9.06e-3)" 2.9 4.1 5.7 2.5 5.7 1.4 5.2 7.3 6.8 4.6 6.6 5.1 2.8 4.3 5.4 3.5 4.6 2.7 4.4 5.6 4.7 4.7 4.3 2.9 3.2 5.4 5.0 5.4 3.9 6.2 6.7 3.3 5.5 5.2 2.8 8.4 4.5 3.8 4.2 5.0 4.2 3.2 4.3 3.9 4.0 2.1 5.4 4.0 6.9 5.2 2.9 4.4 4.2 6.4 4.8 3.8 9.7 9.2 5.2 10.7 7.2 6.5 3.7 2.9 2.1 0.6 0.6 2.0 3.4 5.6 3.6 2.6 4.2 1.6 3.6 1.6 7.2 9.2 3.4 3.0 3.9 3.9 9.7 6.8 7.0 2.0 4.4 9.0 2.2 4.7 1.4 0.1 7.4 1.3 5.1 5.4 7.5 1.3 5.2 4.7 6.3 1.4 5.0 8.1 6.2 7.1 2.9 1.7 4.5 5.7 10.6 11.1 4.4 3.6 5.8 5.4 2.6 0.0 0.0 1.6 0.1 3.2 2.2 0.4 0.2 0.2 0.2 0.1 0.1 0.5 0.2 0.3 0.1 0.3 0.5 0.3 0.3 0.3 0.1 0.2 0.0 0.1 5.7 5.7 7.3 6.8 5.6 4.7 5.4 5.0 5.5 4.3 5.4 6.4 8.4 19.2 33.5 21.9 9.3 3.4 8.1 3.3 18.8 33.6 10.5 11.2 22.5 15.7 25.1 9.2 29.2 7.5 5.0 7.3 9.8 7.2 2.2 8.1 15.0 12.7 6.1 7.6 24.9 3.3 3.6 12.6 15.3 7.1 10.1 20.2 13.6 4.9 3.9 40.4 25.2 10.1 6.1 7.3 2.7 2.5 15.8 6.1 0.0 11.2 8.9 16.4 13.4 28.1 15.8 7.5 4.5 13.5 5.8 9.5 5.8 5.2 13.7 35.2 13.1 16.2 11.5 6.8 7.9 9.4 4.5 5.6 10.8 23.0 7.1 6.2 ZNF613 FLJ13590 ENSG00000176024 "Zinc finger protein 613" Q6PF04 19 51927147-51948759 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 19.4" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "prostate cancer: 10.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA026833 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 1: Thyroid gland - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm Vesicles "HPA026833: AB_1859377" "unprognostic (1.10e-1)" "unprognostic (2.57e-1)" "unprognostic (9.27e-2)" "unprognostic (2.84e-1)" "unprognostic (9.31e-3)" "unprognostic (1.79e-1)" "unprognostic (2.25e-2)" "unprognostic (1.08e-1)" "unprognostic (1.33e-2)" "unprognostic (1.91e-1)" "unprognostic (2.73e-1)" "unprognostic (5.30e-2)" "unprognostic (5.30e-3)" "unprognostic (1.12e-1)" "unprognostic (1.79e-1)" "unprognostic (4.78e-3)" "prognostic favorable (1.92e-6)" 3.2 3.2 3.4 2.6 3.8 1.4 7.0 4.6 4.2 3.1 3.2 5.2 2.2 3.5 3.8 3.4 3.2 2.8 3.5 3.5 5.1 4.9 2.9 3.8 4.2 4.0 4.2 3.8 2.5 6.0 3.2 6.6 3.9 19.4 5.0 7.2 2.9 4.0 2.7 3.6 2.9 4.1 3.5 4.3 2.8 2.8 4.0 5.6 4.3 3.5 4.2 3.6 2.8 4.2 2.9 3.8 6.2 6.3 5.5 5.7 1.5 5.0 7.8 6.4 8.1 1.3 3.5 2.7 2.6 6.1 5.8 3.2 6.3 6.1 6.9 0.1 8.2 5.4 2.8 3.7 5.5 0.3 7.2 4.6 7.1 6.2 5.0 7.7 7.1 6.2 2.5 0.0 6.6 0.5 8.9 4.1 4.5 1.3 5.9 4.7 7.0 2.8 6.5 9.9 4.2 4.0 8.0 5.8 4.6 9.8 6.3 6.4 4.6 2.7 5.3 2.2 5.3 5.5 0.0 4.9 0.1 0.0 8.5 5.7 5.2 10.5 7.1 5.3 6.5 6.0 7.4 8.3 7.0 9.0 7.6 9.9 5.4 7.7 9.4 3.5 7.7 5.4 3.4 3.8 4.6 4.2 3.5 5.1 4.0 4.2 3.9 3.5 4.0 4.2 2.0 3.2 2.6 2.0 0.9 0.5 0.6 0.8 0.6 2.4 1.6 1.0 4.6 1.5 2.7 3.7 0.0 6.1 1.5 1.9 3.9 2.5 2.3 1.2 1.2 3.0 1.2 0.0 2.4 2.2 1.7 1.2 1.5 1.6 1.3 4.9 3.3 1.5 3.2 0.0 2.0 3.7 6.1 1.6 1.5 1.2 1.2 1.2 0.0 4.7 3.0 2.3 3.1 4.5 4.6 1.8 2.1 1.5 0.5 1.6 1.0 1.4 0.5 4.0 0.0 1.6 1.5 1.9 2.1 1.5 0.6 7.1 1.4 2.3 2.1 0.7 ZNF614 FLJ21941 ENSG00000142556 "Zinc finger protein 614" Q8N883 19 52012765-52030240 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 47.9;Late spermatids: 34.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021197 Uncertain Approved Nucleoplasm,Vesicles,Cytosol No No "Cluster 40: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "Vesicles, Cytosol" "HPA021197: AB_1859380" "unprognostic (1.30e-1)" "unprognostic (2.37e-2)" "unprognostic (3.24e-2)" "unprognostic (1.30e-1)" "unprognostic (7.67e-3)" "unprognostic (2.68e-1)" "unprognostic (4.74e-3)" "unprognostic (5.07e-3)" "unprognostic (1.09e-1)" "unprognostic (1.32e-1)" "unprognostic (1.60e-1)" "unprognostic (1.74e-2)" "unprognostic (1.66e-2)" "unprognostic (3.06e-2)" "unprognostic (1.57e-1)" "unprognostic (2.30e-1)" "unprognostic (7.15e-3)" 4.1 3.6 4.0 3.3 4.6 6.3 5.6 8.2 5.3 4.2 2.4 3.0 2.5 5.3 3.9 3.4 4.2 3.3 4.0 3.7 4.8 3.8 2.3 3.5 4.3 4.5 4.6 7.5 1.8 5.0 3.3 6.9 4.3 8.9 3.0 8.7 3.0 4.7 4.0 4.3 2.9 4.9 4.1 4.5 3.2 6.9 5.2 5.9 8.0 5.0 4.4 3.9 2.1 6.4 4.8 3.5 8.8 11.5 6.2 6.9 1.1 6.4 4.5 5.8 7.0 4.4 2.7 12.1 3.4 5.5 5.4 2.0 13.3 8.5 8.6 3.2 18.8 18.2 6.6 9.0 5.1 3.8 8.8 5.4 4.6 5.9 8.2 5.8 6.9 10.5 9.9 2.6 7.9 1.9 16.0 7.6 10.2 0.7 6.3 10.5 17.0 10.0 6.0 12.0 11.6 7.1 3.8 4.7 3.9 10.8 6.3 9.6 7.1 5.7 7.9 3.2 7.6 5.2 8.7 18.3 5.5 5.2 7.6 2.3 2.4 1.6 3.2 3.2 3.9 3.0 2.9 3.1 3.0 2.8 4.1 2.6 1.7 5.7 2.8 1.7 3.2 1.8 4.0 4.6 8.2 5.3 3.7 4.8 4.5 4.6 4.3 4.1 5.2 6.4 5.2 0.0 2.2 3.6 4.8 3.2 5.3 2.4 4.6 6.8 4.2 4.2 5.8 4.3 4.9 5.5 4.2 6.1 6.5 1.7 0.0 2.9 47.9 2.8 6.1 5.8 5.4 7.4 6.6 0.9 7.1 3.7 5.6 3.7 7.0 5.0 8.2 1.6 2.3 16.8 6.7 2.4 2.0 4.1 2.3 34.9 4.1 3.2 1.8 4.7 2.2 5.1 10.3 6.0 9.2 1.4 0.7 7.2 5.4 4.6 1.8 2.0 0.9 5.6 0.0 7.1 5.7 2.2 5.0 4.4 2.7 14.4 4.1 2.7 2.2 5.1 ZNF624 KIAA1349 ENSG00000197566 "Zinc finger protein 624" Q9P2J8 17 16620734-16653856 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 16.6;Oligodendrocytes: 21.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SuSa: 12.1" "Low region specificity" "Detected in all" "HPA023157, HPA023244" Uncertain Approved Vesicles NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 23: Spermatids - Flagellum & Golgi organization" Vesicles "HPA023157: AB_2671094, HPA023244: AB_2671117" "unprognostic (2.47e-1)" "unprognostic (8.75e-2)" "unprognostic (3.51e-2)" "unprognostic (3.97e-3)" "unprognostic (1.64e-1)" "unprognostic (3.77e-2)" "unprognostic (1.24e-1)" "unprognostic (2.18e-1)" "unprognostic (1.10e-2)" "unprognostic (4.76e-2)" "unprognostic (1.40e-1)" "unprognostic (1.62e-1)" "unprognostic (1.75e-2)" "unprognostic (1.52e-1)" "unprognostic (7.88e-2)" "unprognostic (1.09e-1)" "unprognostic (2.97e-1)" 1.6 0.7 1.3 1.5 2.2 1.1 1.8 1.4 2.5 2.3 0.3 1.7 1.3 2.5 1.2 1.3 2.0 1.2 1.5 1.2 1.8 1.8 0.8 2.0 2.4 2.5 1.9 3.6 0.8 2.5 0.4 3.0 2.1 1.0 1.8 2.6 0.9 1.5 0.4 1.5 1.4 2.0 1.8 3.5 1.9 4.8 2.5 3.1 2.3 0.9 2.1 1.4 0.9 4.1 1.1 1.8 5.3 1.8 2.6 3.1 1.4 1.8 3.1 3.4 3.1 0.9 1.0 2.7 1.5 2.4 1.1 1.5 1.5 1.9 3.7 2.9 1.8 3.0 0.9 0.8 2.5 2.1 2.9 3.5 4.4 1.9 3.8 1.8 3.1 3.4 1.9 0.7 4.5 1.6 5.2 0.8 0.9 3.8 0.8 5.5 9.0 0.8 2.3 2.2 1.6 3.2 2.0 1.5 2.1 12.1 1.2 0.9 4.4 3.2 1.2 1.2 1.3 1.2 0.9 0.0 1.5 0.0 2.7 1.0 1.0 2.0 1.7 3.3 2.5 1.6 2.0 2.0 1.9 2.9 2.2 1.3 0.2 2.8 1.5 0.5 1.5 1.1 1.3 2.2 1.4 2.5 1.2 1.8 2.5 1.9 2.1 1.8 2.5 4.1 4.2 0.0 0.0 5.9 2.9 0.5 0.4 1.1 0.6 5.1 1.4 1.0 2.6 1.5 2.2 0.0 2.1 1.3 2.4 1.9 3.9 1.3 11.2 1.3 4.1 3.0 0.0 1.7 5.6 1.0 1.5 2.7 1.5 1.4 3.8 4.1 4.6 0.3 2.6 8.4 9.6 1.3 0.0 4.6 1.6 2.1 1.5 2.3 0.0 8.4 1.2 2.8 2.1 16.6 21.1 1.5 0.8 2.6 0.6 0.5 0.8 2.0 3.6 3.2 0.0 2.4 4.1 12.0 8.4 0.9 0.9 1.5 2.3 4.6 0.9 1.1 ZNF626 ENSG00000188171 "Zinc finger protein 626" Q68DY1 19 20619939-20661596 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-266/84: 19.8" HPA045631 Uncertain Approved "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 37: B-cells - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nuclear membrane, Vesicles" Nucleoplasm "HPA045631: AB_2679397" "unprognostic (1.75e-1)" "unprognostic (4.38e-2)" "unprognostic (3.58e-2)" "unprognostic (1.04e-1)" "unprognostic (2.53e-2)" "unprognostic (2.18e-2)" "unprognostic (6.24e-2)" "unprognostic (2.95e-2)" "unprognostic (1.23e-2)" "unprognostic (6.51e-3)" "unprognostic (1.92e-1)" "unprognostic (2.49e-1)" "unprognostic (5.10e-2)" "unprognostic (1.73e-2)" "unprognostic (1.05e-1)" "unprognostic (2.12e-2)" "unprognostic (2.31e-1)" 7.4 8.9 3.0 5.4 4.7 3.8 16.1 4.8 4.5 8.4 4.8 3.7 1.6 11.2 7.8 6.3 12.2 9.3 10.0 3.0 3.8 11.0 5.7 5.2 12.2 2.5 3.4 25.9 7.2 21.4 3.6 7.3 2.7 11.0 3.2 7.5 7.0 9.7 4.6 9.3 2.4 9.4 3.1 7.0 8.0 5.0 3.8 8.6 23.7 5.9 9.7 14.8 4.1 5.8 0.1 0.0 5.9 0.4 6.8 8.7 0.3 6.5 0.6 9.1 7.9 0.1 0.1 0.5 3.0 8.3 10.7 1.1 0.0 0.2 11.6 0.1 0.2 0.0 0.2 2.3 12.1 0.1 0.0 16.6 2.6 5.5 2.8 0.1 4.3 0.1 4.1 0.6 9.6 0.1 0.4 1.1 12.0 0.0 2.9 5.7 4.1 2.1 8.4 6.4 1.6 10.6 0.1 0.7 6.0 10.6 13.7 0.1 0.1 4.2 0.2 16.4 0.5 9.0 19.8 8.6 0.1 0.1 0.5 0.9 1.1 6.3 7.2 1.1 6.8 8.4 7.6 8.2 3.2 10.5 7.0 6.3 11.2 9.8 4.8 4.2 3.8 3.8 3.0 4.7 4.8 4.5 3.0 3.8 2.5 3.4 2.7 3.1 3.8 5.8 14.0 3.2 8.2 26.4 18.5 9.4 13.7 4.2 10.2 11.1 18.2 18.8 9.8 12.8 6.7 27.6 10.4 17.5 11.1 1.4 31.3 8.7 1.3 19.3 15.0 11.6 2.4 1.7 29.3 9.5 24.9 13.9 6.1 20.8 7.0 19.7 17.2 7.4 11.0 13.5 27.6 1.3 6.1 4.7 9.8 1.7 18.6 5.1 5.4 15.9 2.9 16.2 19.6 37.7 43.0 9.1 0.4 15.4 3.9 17.2 0.1 30.8 12.3 9.5 13.1 11.4 11.9 10.1 16.2 6.1 12.6 43.4 12.3 39.8 0.8 15.5 ZNF638 "MGC26130, NP220, ZFML, Zfp638" ENSG00000075292 "Zinc finger protein 638" Q14966 2 71276561-71435069 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 342.3;Oligodendrocytes: 619.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036784, HPA057395" Supported Enhanced Nucleoplasm,Vesicles NA NA "Cluster 46: Basophils - DNA binding" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 52: Non-specific - Transcription" Nucleoplasm Vesicles "HPA036784: AB_10672478, HPA057395: AB_2683426" "unprognostic (2.58e-2)" "unprognostic (3.15e-1)" "unprognostic (7.57e-2)" "unprognostic (1.26e-3)" "unprognostic (2.18e-2)" "unprognostic (1.29e-1)" "unprognostic (1.35e-2)" "unprognostic (5.68e-3)" "unprognostic (2.31e-2)" "unprognostic (1.11e-1)" "unprognostic (1.69e-1)" "unprognostic (1.32e-1)" "unprognostic (2.66e-3)" "unprognostic (3.28e-1)" "unprognostic (7.68e-2)" "unprognostic (1.93e-2)" "prognostic favorable (8.73e-5)" 21.1 22.1 35.7 21.6 48.9 28.2 24.6 77.6 52.3 23.0 37.7 22.0 15.6 29.2 18.4 19.8 22.1 19.1 41.0 35.7 41.3 24.2 30.9 21.2 25.0 41.9 36.8 37.3 21.9 27.9 24.9 23.2 41.9 22.2 19.5 48.6 21.0 19.5 51.5 16.8 19.0 22.9 34.8 23.1 21.8 29.7 38.9 30.9 29.8 33.7 22.6 21.3 17.1 82.5 36.2 51.0 77.0 36.1 44.4 48.3 59.2 40.4 46.6 33.6 30.0 49.2 34.6 59.2 36.6 37.1 52.3 29.9 72.1 41.4 48.7 60.5 40.1 77.8 54.8 45.4 38.3 72.0 50.6 30.8 39.5 36.1 66.7 47.8 52.5 39.2 79.4 33.8 49.6 36.1 50.9 52.9 66.7 54.1 32.4 43.0 116.5 41.7 36.0 54.3 59.0 38.7 49.8 34.7 52.8 76.3 32.3 43.7 54.3 41.4 60.0 31.1 41.2 27.6 45.7 57.4 34.8 46.3 45.8 64.1 17.0 33.5 18.1 16.3 17.2 25.4 17.1 17.2 14.0 26.0 22.5 16.7 29.1 21.5 24.1 17.7 16.0 10.8 35.7 48.9 77.6 52.3 35.7 41.3 41.9 36.8 41.9 34.8 38.9 82.5 63.1 67.3 112.4 227.9 63.9 31.7 56.8 40.8 46.1 111.5 36.8 35.4 107.0 27.1 59.0 40.5 123.0 42.5 46.7 39.2 19.6 43.0 15.7 54.2 63.7 65.9 38.4 57.2 286.9 40.9 29.0 83.5 50.0 59.2 79.1 112.8 38.6 48.6 32.5 67.3 268.4 34.2 32.6 41.9 33.3 15.8 75.2 49.6 23.2 225.8 71.6 56.4 56.7 342.3 619.5 39.6 35.7 63.9 50.5 60.0 38.1 21.6 74.7 104.0 32.9 98.3 73.1 110.1 78.3 37.4 30.3 50.2 56.1 74.0 36.8 58.9 ZNF644 "BM-005, KIAA1221, MGC60165, MGC70410" ENSG00000122482 "Zinc finger protein 644" Q9H582 1 90915298-91022272 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 262.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057795 Uncertain Uncertain Vesicles NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Vesicles "HPA057795: AB_2683529" "unprognostic (8.20e-2)" "unprognostic (5.86e-3)" "prognostic favorable (4.27e-4)" "prognostic unfavorable (8.39e-4)" "unprognostic (3.19e-3)" "unprognostic (4.62e-3)" "unprognostic (8.04e-2)" "unprognostic (7.01e-2)" "unprognostic (2.44e-2)" "unprognostic (6.32e-2)" "unprognostic (1.70e-1)" "unprognostic (1.16e-1)" "unprognostic (2.61e-2)" "unprognostic (3.03e-1)" "unprognostic (5.09e-2)" "unprognostic (1.03e-1)" "unprognostic (3.07e-1)" 12.4 9.8 17.4 11.7 23.4 17.3 17.1 24.5 22.3 15.7 13.3 13.3 8.5 17.2 11.4 10.3 10.9 10.2 10.0 15.3 18.0 11.0 19.8 10.3 15.9 19.0 20.8 14.7 9.6 12.6 7.9 13.2 19.4 11.6 13.4 11.2 15.4 10.4 14.5 10.4 10.5 12.2 18.8 13.2 10.5 13.1 18.6 19.7 18.7 17.4 15.3 13.5 12.1 28.4 24.1 11.2 32.0 17.1 14.9 17.1 19.4 21.0 21.1 22.1 24.1 15.4 8.3 29.0 23.2 15.6 29.3 19.1 31.6 23.7 33.4 21.5 19.8 38.3 21.8 21.1 20.6 34.6 11.9 16.3 27.0 22.4 30.1 20.8 23.8 21.6 26.8 32.0 23.6 9.5 27.9 30.0 30.3 12.5 22.7 28.7 52.3 16.6 23.5 21.5 25.8 20.6 24.5 19.1 55.2 21.7 12.4 33.7 19.0 24.5 21.3 20.4 31.9 24.5 17.8 39.7 10.3 25.8 12.9 5.4 3.5 4.0 4.6 3.6 5.3 6.8 5.0 5.3 4.4 5.2 6.4 5.5 1.1 9.9 3.8 5.4 4.4 2.6 17.4 23.4 24.5 22.3 15.3 18.0 19.0 20.8 19.4 18.8 18.6 28.4 72.6 70.5 30.0 98.9 85.9 54.2 98.9 45.0 48.3 37.3 49.8 45.0 51.2 28.6 47.0 11.0 25.0 25.6 85.2 34.3 31.3 31.1 11.4 87.3 68.7 44.9 55.0 30.9 96.0 22.6 19.6 51.8 43.8 107.9 43.2 51.9 27.1 26.1 22.5 55.5 106.2 30.4 36.7 29.2 38.6 13.3 46.6 49.7 35.6 124.6 30.7 40.2 38.1 144.3 262.3 29.6 29.2 34.6 79.6 58.8 22.2 29.2 41.7 36.8 52.6 83.5 67.4 51.5 49.2 39.8 47.5 12.0 72.9 44.5 34.0 75.2 ZNF691 Zfp691 ENSG00000164011 "Zinc finger protein 691" Q5VV52 1 42846573-42852477 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062527 Approved Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Nucleoli, Vesicles" "HPA062527: AB_2684791" "unprognostic (4.34e-2)" "unprognostic (4.05e-2)" "unprognostic (1.09e-1)" "unprognostic (4.32e-2)" "unprognostic (4.86e-2)" "unprognostic (5.50e-2)" "prognostic unfavorable (7.33e-6)" "unprognostic (1.40e-3)" "unprognostic (2.65e-3)" "unprognostic (5.12e-2)" "prognostic favorable (6.25e-5)" "unprognostic (1.24e-1)" "unprognostic (1.06e-2)" "unprognostic (1.41e-1)" "unprognostic (1.78e-1)" "unprognostic (1.00e-1)" "unprognostic (1.05e-1)" 5.9 9.8 11.0 8.8 11.9 2.3 11.2 11.4 14.4 11.1 11.7 9.7 6.5 9.9 15.1 6.1 9.9 6.1 9.1 10.6 11.7 11.6 18.2 7.3 13.0 12.3 11.5 13.0 8.9 13.6 9.2 9.3 12.1 10.5 7.2 11.3 9.8 11.0 8.0 9.5 7.5 9.5 11.1 12.1 7.7 6.7 12.3 15.5 12.1 9.9 12.7 9.0 7.0 12.6 6.6 9.1 18.1 15.0 16.0 12.2 2.3 7.7 9.3 12.4 12.3 6.5 9.5 16.2 11.8 7.3 6.2 11.5 17.6 10.3 10.6 29.3 17.8 17.0 27.2 11.7 11.9 6.6 3.5 10.6 12.3 15.6 12.7 15.1 12.8 15.8 16.8 6.9 12.3 5.3 19.8 8.7 27.1 7.2 6.8 13.2 22.8 11.2 11.6 6.2 13.0 12.9 7.9 14.2 13.3 26.9 7.8 22.2 6.7 12.3 12.8 7.0 8.6 16.5 14.0 4.7 8.6 7.8 10.6 24.5 12.7 19.2 12.9 11.5 17.0 17.2 17.4 17.8 12.7 23.4 16.8 16.6 6.9 21.3 12.4 14.1 23.1 14.8 11.0 11.9 11.4 14.4 10.6 11.7 12.3 11.5 12.1 11.1 12.3 12.6 3.6 6.4 2.7 2.6 4.1 1.8 2.7 4.1 2.8 2.5 4.5 5.6 6.5 10.0 2.7 5.5 4.2 6.5 1.4 1.4 7.9 5.5 6.8 1.2 3.3 5.1 3.0 3.0 2.0 3.8 5.3 4.3 3.1 1.2 5.1 5.3 5.0 7.6 6.8 1.7 2.3 2.8 6.1 4.1 1.2 3.2 7.2 3.0 1.8 3.7 3.1 6.4 5.2 5.0 4.1 2.3 3.2 7.2 2.3 3.2 3.5 9.6 3.2 4.2 0.0 2.3 3.2 10.4 7.4 3.1 0.9 3.3 3.3 5.3 2.4 1.2 ZNF768 FLJ23436 ENSG00000169957 "Zinc finger protein 768" Q9H5H4 16 30524004-30526821 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 50.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024630, HPA066512" Supported Approved Nucleoplasm,Vesicles NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm Vesicles "HPA024630: AB_1859446, HPA066512: AB_2685683" "unprognostic (2.33e-1)" "unprognostic (6.16e-2)" "unprognostic (2.28e-2)" "unprognostic (1.20e-1)" "unprognostic (4.86e-2)" "unprognostic (1.73e-1)" "unprognostic (7.94e-3)" "unprognostic (1.61e-1)" "unprognostic (1.63e-1)" "unprognostic (1.11e-1)" "unprognostic (3.26e-2)" "unprognostic (2.74e-1)" "prognostic favorable (9.30e-6)" "unprognostic (4.49e-2)" "unprognostic (1.94e-1)" "unprognostic (3.13e-1)" "prognostic favorable (6.46e-4)" 22.3 23.2 31.4 9.9 32.9 13.3 22.6 30.6 35.0 28.7 28.3 42.6 29.8 30.8 9.9 22.8 27.5 10.1 49.3 27.8 27.7 34.8 38.5 19.0 7.3 32.3 31.9 28.9 25.7 30.2 27.2 11.3 30.3 30.3 17.0 13.7 25.6 21.1 93.8 28.2 31.1 13.4 28.5 22.1 30.9 39.3 33.0 6.0 23.7 53.1 7.4 34.9 23.0 29.9 27.1 33.3 37.0 36.1 17.6 20.3 29.1 20.2 22.5 32.7 28.4 21.3 36.8 17.1 30.1 14.2 26.3 35.4 24.8 24.1 19.4 38.5 52.6 40.0 24.0 30.0 44.1 26.8 121.3 17.9 52.5 25.1 32.4 30.2 21.9 6.7 47.4 28.0 17.1 74.9 10.0 64.7 34.8 22.0 27.1 50.7 24.7 42.5 23.9 14.0 43.6 48.4 11.5 59.9 77.3 15.9 59.3 66.5 14.9 34.2 25.9 19.4 22.8 41.3 32.4 21.1 28.5 41.4 35.2 0.0 0.4 1.0 0.0 0.6 0.1 1.1 0.1 0.0 0.6 0.4 0.1 0.0 0.5 0.6 0.1 0.5 0.0 0.2 31.4 32.9 30.6 35.0 27.8 27.7 32.3 31.9 30.3 28.5 33.0 29.9 9.7 9.6 1.9 8.8 4.1 5.5 6.7 9.5 6.8 13.3 15.4 12.6 7.6 14.3 5.5 16.5 2.1 7.2 2.0 50.4 11.7 12.2 18.4 10.9 9.9 9.2 18.0 3.8 2.6 16.2 8.0 6.5 10.7 13.3 3.8 15.5 14.6 17.9 12.7 21.9 3.4 29.1 8.2 8.1 7.7 7.4 10.8 6.1 5.4 4.7 6.8 16.5 0.0 4.0 4.5 11.6 38.2 13.2 2.2 7.9 38.9 17.0 7.4 12.7 6.6 11.8 10.5 15.2 5.1 10.0 5.7 3.6 2.1 14.1 31.3 5.3 ZNF813 FLJ16542 ENSG00000198346 "Zinc finger protein 813" Q6ZN06 19 53467733-53496255 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 13.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RT4: 18.1" HPA056406 Uncertain Approved Vesicles NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 68: Epididymis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" Vesicles "HPA056406: AB_2683119" "unprognostic (1.20e-1)" "unprognostic (3.43e-2)" "unprognostic (1.17e-1)" "unprognostic (3.98e-3)" "unprognostic (2.28e-1)" "unprognostic (3.61e-3)" "unprognostic (1.48e-2)" "unprognostic (1.84e-3)" "unprognostic (3.39e-3)" "unprognostic (1.74e-1)" "unprognostic (3.75e-2)" "unprognostic (3.61e-2)" "unprognostic (1.25e-3)" "unprognostic (8.18e-2)" "unprognostic (1.97e-1)" "unprognostic (1.77e-2)" "unprognostic (6.56e-2)" 1.2 1.1 0.9 1.5 1.3 1.4 2.2 1.1 1.1 1.1 1.4 1.8 1.8 1.3 3.9 1.2 1.8 1.4 0.7 1.0 1.2 1.3 0.7 1.4 2.2 1.4 1.4 1.8 1.3 2.4 0.6 3.6 1.3 4.9 1.7 0.6 1.2 1.1 0.4 2.0 1.7 1.0 1.0 1.9 1.9 1.6 1.3 2.2 1.9 0.5 2.1 1.4 1.2 1.8 0.9 0.8 2.6 4.3 2.2 2.6 6.0 2.4 2.4 1.6 2.3 4.6 2.7 6.9 2.3 2.3 3.0 1.4 6.3 2.7 3.0 0.0 9.9 6.9 1.8 5.2 1.1 0.0 7.1 2.2 2.2 1.8 1.3 0.9 1.4 4.9 3.8 0.1 2.6 1.3 9.2 3.8 3.3 0.8 2.4 5.6 5.7 3.4 1.5 18.1 1.1 2.5 0.0 4.5 1.6 5.6 1.8 3.4 2.3 0.9 3.1 0.1 2.3 3.6 5.5 7.5 0.0 0.0 4.7 1.8 1.1 0.8 1.7 1.6 1.7 1.6 1.6 1.9 1.2 2.4 3.0 2.3 0.5 3.6 3.0 1.1 1.3 1.4 0.9 1.3 1.1 1.1 1.0 1.2 1.4 1.4 1.3 1.0 1.3 1.8 3.4 6.4 1.8 0.3 4.4 1.8 3.1 1.4 4.6 0.7 1.9 1.8 1.9 5.7 2.6 0.0 0.0 5.0 4.3 2.5 1.9 2.2 1.7 2.6 3.2 4.0 0.0 3.4 0.3 1.2 10.1 4.1 3.6 2.6 0.0 7.0 13.6 1.2 2.8 3.3 1.0 3.2 2.0 3.0 1.7 0.9 2.5 2.6 3.6 1.0 3.7 1.1 3.1 2.0 2.8 1.5 3.4 2.2 1.5 5.0 1.2 0.8 2.0 0.6 0.0 4.0 3.4 0.9 4.1 2.2 1.6 8.9 2.8 2.6 3.9 2.3 ZNF891 ENSG00000214029 "Zinc finger protein 891" A8MT65 12 133104779-133130274 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 31.4;Early spermatids: 70.4;Horizontal cells: 40.4;Rod photoreceptor cells: 32.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040301 Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 21: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm Vesicles "HPA040301: AB_10795380" "unprognostic (3.05e-1)" "unprognostic (9.12e-2)" "unprognostic (3.29e-1)" "unprognostic (3.72e-1)" "unprognostic (7.51e-3)" "unprognostic (5.98e-3)" "unprognostic (1.94e-2)" "unprognostic (7.90e-2)" "unprognostic (2.77e-2)" "unprognostic (1.47e-1)" "unprognostic (1.60e-2)" "unprognostic (6.09e-2)" "unprognostic (5.22e-2)" "unprognostic (1.14e-1)" "unprognostic (3.64e-1)" "unprognostic (2.07e-3)" "unprognostic (6.68e-2)" 0.9 1.7 1.4 1.0 1.6 1.3 2.0 3.8 1.7 1.3 1.1 0.9 0.8 2.1 1.4 1.2 1.3 0.9 0.8 1.6 1.1 1.2 0.8 0.9 1.3 1.4 1.3 2.3 0.9 1.3 1.4 1.0 1.2 1.1 1.1 4.7 1.1 1.1 1.0 1.7 0.9 1.5 1.0 1.2 1.0 4.2 1.4 1.3 1.8 1.4 1.3 0.8 0.9 2.8 1.1 1.4 4.1 0.1 1.4 1.9 3.5 0.8 1.2 2.2 1.7 0.9 0.6 0.1 1.1 1.2 2.6 1.6 3.0 1.8 1.6 0.0 2.3 3.7 3.7 1.2 1.4 2.3 1.9 1.4 0.9 2.0 2.0 2.0 1.4 3.0 2.4 0.3 2.2 0.8 3.4 2.6 3.5 2.2 2.0 3.4 3.8 2.4 1.0 2.2 3.5 1.5 3.0 0.6 1.0 3.0 2.9 1.3 0.8 2.0 2.4 1.5 1.5 0.2 0.1 3.4 0.5 0.9 1.5 0.5 0.3 0.6 0.9 0.3 0.7 1.1 0.7 0.9 0.3 1.3 1.3 1.3 0.4 1.0 0.3 0.6 0.9 0.4 1.4 1.6 3.8 1.7 1.6 1.1 1.4 1.3 1.2 1.0 1.4 2.8 6.4 3.2 5.3 2.0 14.3 1.8 5.9 2.3 2.8 31.4 3.2 3.9 5.7 5.7 6.7 11.0 29.2 3.4 5.2 1.1 0.0 3.9 70.4 6.6 11.9 5.9 6.7 4.0 2.8 1.9 2.3 6.2 3.6 5.6 1.3 16.7 6.8 2.0 2.0 40.4 3.4 2.4 0.0 2.8 0.8 10.0 5.3 4.3 1.8 1.9 2.7 10.6 10.3 3.5 3.6 1.8 2.1 6.0 2.7 3.7 2.4 2.2 9.5 32.4 19.7 11.2 8.4 14.2 14.1 3.0 1.7 2.3 6.5 8.9 3.2 2.4 ZNHIT6 "BCD1, C1orf181, FLJ20729, NY-BR-75" ENSG00000117174 "Zinc finger HIT-type containing 6" Q9NWK9 1 85649417-85708433 "Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018132 Uncertain Approved "Nuclear speckles,Vesicles" No No "Cluster 21: B-cells - Adaptive immune response" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles, Vesicles" "HPA018132: AB_1848789" "unprognostic (1.37e-1)" "unprognostic (4.01e-1)" "unprognostic (1.24e-1)" "unprognostic (2.27e-3)" "unprognostic (1.61e-2)" "unprognostic (1.11e-1)" "prognostic unfavorable (6.08e-6)" "unprognostic (1.11e-1)" "unprognostic (3.89e-2)" "unprognostic (8.48e-2)" "unprognostic (9.91e-3)" "unprognostic (2.92e-2)" "unprognostic (1.27e-3)" "unprognostic (5.91e-2)" "unprognostic (9.85e-2)" "unprognostic (1.15e-1)" "unprognostic (7.37e-2)" 10.3 6.6 7.2 5.2 8.2 5.2 10.1 6.8 7.7 14.6 5.3 9.7 2.9 11.0 4.4 11.8 9.6 3.6 7.7 6.8 7.9 9.0 6.7 6.9 6.4 7.7 7.4 10.4 7.2 4.2 7.5 4.7 7.6 8.9 4.2 3.3 9.5 4.4 7.8 11.1 7.9 5.5 8.1 8.1 6.9 6.1 7.6 5.5 8.5 3.9 6.0 11.6 11.3 9.1 13.5 9.1 8.9 8.1 19.2 17.4 11.3 17.0 16.3 11.5 11.0 9.2 6.8 10.4 19.7 10.4 24.7 11.2 15.9 10.9 18.6 14.3 13.7 21.6 10.3 10.7 16.2 35.4 8.3 17.2 10.0 15.3 13.4 11.4 13.7 16.4 20.2 13.3 17.6 5.1 20.9 9.2 13.5 11.0 16.5 16.6 19.7 12.0 18.7 25.2 8.6 5.6 13.3 20.3 19.3 9.3 9.0 8.9 15.6 14.8 10.0 12.5 24.7 8.5 9.3 28.2 3.4 22.0 13.1 0.6 0.7 0.1 1.8 0.7 2.0 1.9 1.6 2.0 1.2 2.4 2.0 2.0 0.1 1.8 0.7 2.1 1.8 0.8 7.2 8.2 6.8 7.7 6.8 7.9 7.7 7.4 7.6 8.1 7.6 9.1 22.0 16.0 22.5 22.5 20.3 16.2 14.4 12.5 13.1 31.8 10.6 9.9 17.6 11.5 38.0 31.3 33.3 9.0 21.0 25.6 3.9 11.9 4.2 15.5 47.4 20.9 9.5 8.4 40.4 8.8 13.7 22.2 6.1 16.1 27.8 22.4 14.3 10.6 7.5 15.2 30.0 20.9 16.2 13.5 7.4 3.8 13.4 9.1 7.2 22.5 11.0 17.6 27.8 34.2 45.3 12.2 11.6 12.8 11.1 11.1 15.5 6.3 18.0 38.8 19.7 22.4 20.7 35.8 21.6 14.0 16.3 2.7 20.1 25.8 20.5 10.8 ZNRF2 RNF202 ENSG00000180233 "Zinc and ring finger 2" Q8NHG8 7 30284597-30367689 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 119.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072244 Approved Uncertain "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Vesicles" "Nucleoli fibrillar center" "HPA072244: AB_2732197" "unprognostic (9.44e-2)" "unprognostic (2.38e-2)" "unprognostic (8.64e-2)" "prognostic unfavorable (7.68e-4)" "unprognostic (4.46e-2)" "unprognostic (1.24e-1)" "unprognostic (3.06e-1)" "unprognostic (6.10e-2)" "unprognostic (1.26e-1)" "unprognostic (1.67e-1)" "unprognostic (1.71e-1)" "unprognostic (5.93e-2)" "prognostic favorable (2.29e-4)" "unprognostic (1.51e-1)" "unprognostic (2.71e-1)" "prognostic favorable (8.71e-4)" "unprognostic (8.67e-2)" 7.4 6.5 4.8 11.5 5.3 13.0 9.6 5.5 4.2 5.1 14.5 18.9 13.2 8.4 10.7 10.4 4.4 9.4 5.1 4.3 4.0 22.0 21.5 7.4 15.3 7.4 6.6 3.7 10.3 9.1 5.0 9.3 6.0 5.7 16.2 4.7 9.2 5.3 5.7 10.0 15.2 9.5 7.5 10.8 15.0 24.0 7.9 8.9 11.7 6.2 13.2 11.2 4.2 8.4 13.2 4.7 3.8 3.4 4.4 3.0 19.8 4.9 5.1 5.4 7.2 2.4 21.5 13.8 12.6 4.1 14.0 12.5 12.7 8.5 5.7 13.4 11.5 8.6 9.7 6.4 2.3 6.7 15.6 4.6 14.0 3.7 9.1 5.6 4.6 10.5 10.7 26.6 5.9 5.1 13.6 17.5 8.9 13.2 5.9 11.7 8.2 23.8 16.4 28.0 13.0 12.3 9.9 41.2 8.5 22.2 11.1 26.5 5.1 5.2 8.9 5.0 10.5 44.9 41.5 18.1 5.7 14.3 7.8 0.2 0.3 0.4 0.3 0.3 0.5 0.4 0.4 0.5 0.3 0.2 0.2 0.4 0.5 0.3 0.4 2.2 1.0 0.2 4.8 5.3 5.5 4.2 4.3 4.0 7.4 6.6 6.0 7.5 7.9 8.4 11.3 9.6 8.4 19.9 13.9 15.9 7.4 4.8 8.6 11.3 26.5 10.4 3.6 14.3 5.0 16.5 41.7 10.1 40.8 60.0 7.9 4.9 5.2 32.7 7.6 6.6 31.3 6.1 54.4 10.3 11.4 5.1 14.3 43.7 3.8 4.7 8.2 41.6 10.7 1.7 32.3 14.0 0.0 23.3 16.2 10.1 2.8 23.1 12.4 119.9 13.1 5.1 4.1 41.7 39.7 7.4 19.5 2.2 11.5 8.5 22.6 32.3 5.8 5.8 6.6 7.7 9.8 18.3 7.0 7.9 18.9 11.5 17.6 7.6 23.4 14.3 ZPR1 ZNF259 ENSG00000109917 "ZPR1 zinc finger" O75312 11 116773799-116788039 "Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 228.5;Late spermatids: 418.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022596, HPA030979" Uncertain Approved Vesicles NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 23: Testis - Cell cycle regulation" "Cluster 3: HMC-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "CAB022596: , HPA030979: AB_2673684" "unprognostic (2.12e-2)" "unprognostic (3.55e-1)" "unprognostic (6.22e-2)" "unprognostic (1.44e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (8.01e-4)" "prognostic unfavorable (5.87e-6)" "unprognostic (1.04e-1)" "unprognostic (1.09e-1)" "unprognostic (9.42e-2)" "unprognostic (4.96e-3)" "unprognostic (4.79e-2)" "unprognostic (2.17e-2)" "unprognostic (1.48e-1)" "unprognostic (1.73e-1)" "unprognostic (1.71e-2)" "unprognostic (6.66e-2)" 21.2 12.3 12.2 14.3 12.7 35.2 16.5 10.9 13.4 13.4 8.3 13.9 10.6 14.0 13.0 16.5 13.5 11.6 14.3 13.7 13.6 16.3 24.5 14.4 15.6 12.4 12.2 15.2 21.1 9.6 11.8 12.8 12.6 13.3 12.6 5.6 12.3 12.3 28.4 15.3 14.2 15.6 13.6 14.1 16.1 27.3 14.0 13.9 14.1 14.3 18.7 20.3 13.6 14.2 23.3 33.3 19.4 36.9 29.0 30.1 25.7 39.0 30.6 34.4 36.6 84.0 41.1 53.2 67.4 39.1 61.9 31.0 53.9 35.7 48.5 34.7 26.5 112.6 18.1 45.6 57.4 51.4 45.2 28.7 49.3 65.6 105.6 23.0 38.7 33.8 54.4 35.3 50.7 28.9 42.3 64.0 35.5 63.9 49.7 32.9 29.6 58.9 33.1 40.0 25.3 43.7 32.0 42.2 28.1 33.1 28.5 34.9 33.3 44.3 22.0 26.2 55.6 24.6 19.8 64.3 24.2 89.9 43.5 12.7 20.7 16.5 15.9 22.2 18.5 28.1 21.6 20.5 22.5 22.6 21.2 19.3 3.0 24.5 18.5 16.2 23.7 20.3 12.2 12.7 10.9 13.4 13.7 13.6 12.4 12.2 12.6 13.6 14.0 14.2 23.8 9.6 15.9 0.7 37.0 0.0 66.3 0.0 32.5 8.8 21.6 20.1 11.7 20.0 9.9 20.2 0.0 34.5 36.3 13.6 45.0 45.8 228.5 18.9 20.1 22.0 23.4 14.7 1.1 40.2 58.0 21.3 18.8 24.2 28.0 29.9 13.9 19.9 36.3 5.0 1.4 19.2 0.0 19.5 0.0 418.8 19.0 25.1 0.0 1.9 36.6 7.9 26.8 1.0 2.4 62.5 20.3 12.4 29.4 83.1 42.5 28.8 2.9 6.2 6.6 29.3 23.3 75.2 33.2 30.4 0.0 45.8 34.3 27.1 25.4 84.2 ZSWIM3 "C20orf164, dJ337O18.7, PPP1R174" ENSG00000132801 "Zinc finger SWIM-type containing 3" Q96MP5 20 45857614-45879122 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 7.6;Inhibitory neurons: 9.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055692, HPA060508" Uncertain Approved "Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Transcription" Vesicles "Nucleoli fibrillar center, Cytosol" "HPA055692: AB_2682887, HPA060508: AB_2684297" "prognostic unfavorable (9.32e-5)" "unprognostic (8.53e-2)" "unprognostic (3.55e-1)" "prognostic unfavorable (4.21e-4)" "unprognostic (4.61e-2)" "unprognostic (1.09e-3)" "unprognostic (1.77e-3)" "unprognostic (4.49e-2)" "unprognostic (2.20e-1)" "unprognostic (1.36e-2)" "unprognostic (2.72e-3)" "unprognostic (9.28e-2)" "unprognostic (4.74e-2)" "unprognostic (5.55e-2)" "unprognostic (1.76e-1)" "unprognostic (4.69e-2)" "unprognostic (4.13e-2)" 1.3 2.9 2.3 2.0 2.2 0.7 1.8 2.8 2.5 1.8 1.4 2.3 2.4 1.9 2.8 1.8 2.1 1.5 2.0 2.1 2.3 1.8 2.3 1.9 3.4 2.0 2.1 2.7 1.5 2.2 1.9 1.7 2.1 1.9 2.3 3.3 1.8 1.6 1.4 2.2 2.4 1.7 2.0 3.2 1.8 3.2 2.2 3.5 1.9 2.4 3.9 1.6 1.4 2.1 1.7 1.4 4.1 2.4 4.9 3.5 2.4 2.6 3.1 4.7 4.6 5.9 2.6 5.3 8.8 2.2 2.3 2.8 5.9 2.8 3.5 3.3 2.5 5.1 2.6 3.8 5.9 2.9 6.7 3.2 3.1 3.6 2.2 5.0 4.1 4.6 4.8 2.5 3.6 8.5 4.0 5.8 1.6 3.9 5.6 3.9 3.8 4.0 1.3 1.0 5.4 2.7 4.2 4.8 3.3 3.1 2.3 7.6 4.1 4.7 1.5 1.8 1.6 5.4 3.0 3.4 4.0 3.4 1.5 1.0 1.1 1.6 1.3 1.5 2.8 2.1 1.5 2.0 1.9 1.8 1.4 1.9 0.8 1.7 4.8 1.1 2.4 1.1 2.3 2.2 2.8 2.5 2.1 2.3 2.0 2.1 2.1 2.0 2.2 2.1 1.6 3.2 1.1 4.6 4.1 0.4 0.3 0.7 0.6 4.4 1.1 1.0 1.3 0.0 0.5 1.8 0.0 1.3 1.4 2.8 0.0 1.2 0.5 0.6 1.2 1.8 2.4 0.8 7.6 1.4 0.6 1.4 1.5 1.0 0.0 5.2 2.2 0.8 1.0 0.0 9.2 1.1 0.0 1.3 1.4 0.7 0.3 1.1 0.0 6.5 0.6 2.8 0.0 7.1 7.0 0.6 0.3 1.2 2.6 0.2 2.0 1.2 0.5 4.3 0.0 1.3 1.2 2.4 4.3 1.3 0.3 0.8 3.1 4.7 0.9 0.4